Document S1. Revised gross pathology scoring system for macaques with M. tuberculosis infection. Fig. S1. Least squares means estimates of lung inflammation over time. Fig. S2. Comparison of total FDG lung activity of CCM versus rhesus at each time point. Fig. S3. Coronal view of necrotic and non-necrotic lymph nodes. Fig. S4. Fraction of CFU+ granulomas (or clusters) at time of necropsy. Fig. S5. Bacterial burden in individual lymph nodes is slightly higher in rhesus than in CCM. Table S1. List of animals with CFU dose, infection date, and necropsy date. Table S2. Output for mixed effects model comparing lung inflammation over time by species. Table S3. Output for analysis of covariance (ANCOVA) on total CFU.
PDF, 3.3M