Table S1: Differential expression gene analysis in hypoxia-induced and normoxia-cultured LX-2 cells.,,,,,,,,,,,,, ,,,,,,,,,,,,, Probe Set ID,Gene Symbol,Accession Number,Gene Description,Database Source,Mean Signal of experimental Group ,Mean Signal of control Group ,d Score,Fold Change,p-value,q-value,Gene Feature,Biotype,Rank TC0X000388.hg.1,OGT,NM_181672,"""Homo sapiens O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), transcript variant 1, mRNA.""",RefSeq,5.919128,5.58958,6.798295,1.25662,5.60E-05,0,up,coding,1 TC19001703.hg.1,GYS1,NM_001161587,"""Homo sapiens glycogen synthase 1 (muscle) (GYS1), transcript variant 2, mRNA.""",RefSeq,6.402041,6.111566,6.003345,1.223043,6.60E-05,0,up,coding,2 TC01002578.hg.1,SLC2A1,NM_006516,"""Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1), mRNA.""",RefSeq,7.082137,6.761705,5.823848,1.248704,7.50E-05,0,up,coding,3 TC10001398.hg.1,P4HA1,NM_000917,"""Homo sapiens prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), transcript variant 1, mRNA.""",RefSeq,5.721185,5.380221,5.679114,1.266603,9.00E-05,0,up,coding,4 TC06001421.hg.1,HIST1H2BL,NM_003519,"""Homo sapiens histone cluster 1, H2bl (HIST1H2BL), mRNA.""",RefSeq,4.108352,4.443182,-5.303038,-1.261228,0.000119,0.395935,down,coding,5 TC10001182.hg.1,NAMPTL,ENST00000543053,cdna:known chromosome:GRCh37:10:36811644:36812323:-1 gene:ENSG00000229644 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,3.551144,3.234827,5.248623,1.245148,0.000124,0.037916,up,coding,6 TC11000784.hg.1,PPME1,NM_016147,"""Homo sapiens protein phosphatase methylesterase 1 (PPME1), transcript variant 1, mRNA.""",RefSeq,5.080507,4.780653,5.03629,1.23102,0.000148,0.037916,up,coding,7 TC01003005.hg.1,RSBN1,NM_018364,"""Homo sapiens round spermatid basic protein 1 (RSBN1), mRNA.""",RefSeq,6.131836,5.740713,5.01646,1.311414,0.000173,0.037916,up,coding,8 TC08001062.hg.1,STC1,NM_003155,"""Homo sapiens stanniocalcin 1 (STC1), mRNA.""",RefSeq,6.246296,5.76931,4.886445,1.391833,0.000217,0.037916,up,coding,9 TC19000805.hg.1,ERVV-2,NM_001191055,"""Homo sapiens endogenous retrovirus group V, member 2 (ERVV-2), mRNA.""",RefSeq,4.12375,3.761974,4.761712,1.285007,0.000246,0.037916,up,coding,10 TC11001128.hg.1,OR4D5,NM_001001965,"""Homo sapiens olfactory receptor, family 4, subfamily D, member 5 (OR4D5), mRNA.""",RefSeq,3.326539,2.846014,4.598431,1.395251,0.000275,0.037916,up,coding,11 TC14001088.hg.1,RPL10L,NM_080746,"""Homo sapiens ribosomal protein L10-like (RPL10L), mRNA.""",RefSeq,3.675198,3.958254,-4.442544,-1.216769,0.000309,0.395935,down,coding,12 TC14001141.hg.1,ERO1L,NM_014584,"""Homo sapiens ERO1-like (S. cerevisiae) (ERO1L), mRNA.""",RefSeq,4.227567,3.95207,3.79212,1.210411,0.000771,0.129998,up,coding,13 TC07000874.hg.1,PP12708,ENST00000397584,cdna:known chromosome:GRCh37:7:139073926:139077714:1 gene:ENSG00000214117 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,1.963959,1.677259,3.667514,1.219846,0.000893,0.129998,up,coding,14 TC10001769.hg.1,BNIP3,NM_004052,"""Homo sapiens BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA.""",RefSeq,5.284746,4.986737,3.634845,1.229446,0.000932,0.129998,up,coding,15 TC01004094.hg.1,LYPD8,NM_001085474,"""Homo sapiens LY6/PLAUR domain containing 8 (LYPD8), mRNA.""",RefSeq,5.779471,5.495768,3.634534,1.217316,0.000937,0.129998,up,coding,16 TC01002039.hg.1,OR2T3,NM_001005495,"""Homo sapiens olfactory receptor, family 2, subfamily T, member 3 (OR2T3), mRNA.""",RefSeq,6.106509,5.837139,3.591767,1.205282,0.000995,0.132998,up,coding,17 TC03000036.hg.1,,BC171813,"""Homo sapiens cDNA clone MGC:198528 IMAGE:9054467, complete cds.""",GenBank,5.580974,5.307083,3.586947,1.209065,0.001014,0.132998,up,coding,18 TC06000314.hg.1,OR14J1,NM_030946,"""Homo sapiens olfactory receptor, family 14, subfamily J, member 1 (OR14J1), mRNA.""",RefSeq,2.48135,2.747079,-3.576602,-1.202243,0.001039,0.395935,down,coding,19 TC6_cox_hap2000011.hg.1,OR14J1,NM_030946,"""Homo sapiens olfactory receptor, family 14, subfamily J, member 1 (OR14J1), mRNA.""",RefSeq,2.48135,2.747079,-3.576602,-1.202243,0.001039,0.395935,down,coding,20 TC6_mcf_hap5000006.hg.1,OR14J1,NM_030946,"""Homo sapiens olfactory receptor, family 14, subfamily J, member 1 (OR14J1), mRNA.""",RefSeq,2.48135,2.747079,-3.576602,-1.202243,0.001039,0.395935,down,coding,21 TC21000365.hg.1,KRTAP25-1,NM_001128598,"""Homo sapiens keratin associated protein 25-1 (KRTAP25-1), mRNA.""",RefSeq,2.718859,2.343605,3.51661,1.297068,0.001117,0.132998,up,coding,22 TC01003968.hg.1,EGLN1,NM_022051,"""Homo sapiens egl nine homolog 1 (C. elegans) (EGLN1), mRNA.""",RefSeq,5.42605,5.091498,3.512967,1.260986,0.001126,0.132998,up,coding,23 TC03000482.hg.1,OR5AC2,NM_054106,"""Homo sapiens olfactory receptor, family 5, subfamily AC, member 2 (OR5AC2), mRNA.""",RefSeq,3.678184,3.211214,3.498672,1.382204,0.001156,0.132998,up,coding,24 TC0X000334.hg.1,FOXR2,NM_198451,"""Homo sapiens forkhead box R2 (FOXR2), mRNA.""",RefSeq,3.899233,4.217255,-3.470093,-1.24662,0.001219,0.395935,down,coding,25 TC01002527.hg.1,,ENST00000448796,cdna:novel chromosome:GRCh37:1:38292232:38293886:-1 gene:ENSG00000230610 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,3.647331,4.174369,-3.33936,-1.440967,0.001428,0.395935,down,coding,26 TC0X000689.hg.1,SPANXA1,NM_013453,"""Homo sapiens sperm protein associated with the nucleus, X-linked, family member A1 (SPANXA1), mRNA.""",RefSeq,4.867326,4.599699,3.330865,1.203826,0.001457,0.132998,up,coding,27 TC09000989.hg.1,,ENST00000443737,[retired] cdna:known chromosome:GRCh37:9:27374215:27378942:-1 gene:ENSG00000227975 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,3.471587,3.046609,3.314898,1.342552,0.001486,0.151664,up,coding,28 TC06001299.hg.1,,ENST00000398387,[retired] cdna:known chromosome:GRCh37:6:17878685:17882609:-1 gene:ENSG00000217340 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,2.715737,3.010035,-3.278408,-1.226288,0.001584,0.449671,down,coding,29 TC06001484.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,30 TC6_apd_hap1000059.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,31 TC6_cox_hap2000121.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,32 TC6_dbb_hap3000110.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,33 TC6_mann_hap4000099.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,34 TC6_mcf_hap5000103.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,35 TC6_qbl_hap6000111.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,36 TC6_ssto_hap7000103.hg.1,MAS1L,BC069345,"""Homo sapiens MAS1 oncogene-like, mRNA (cDNA clone MGC:97090 IMAGE:7262308), complete cds.""",GenBank,4.985277,4.717906,3.091568,1.203613,0.002058,0.164572,up,coding,37 TC6_ssto_hap7000009.hg.1,OR14J1,NM_030946,"""Homo sapiens olfactory receptor, family 14, subfamily J, member 1 (OR14J1), mRNA.""",RefSeq,2.63019,3.000646,-2.933032,-1.292761,0.002567,0.521054,down,coding,38 TC11001334.hg.1,OR51B4,BC148186,"""Homo sapiens olfactory receptor, family 51, subfamily B, member 4, mRNA (cDNA clone MGC:129870 IMAGE:40025615), complete cds.""",GenBank,3.94536,3.502938,2.641687,1.358883,0.004304,0.241424,up,coding,39 TC01002035.hg.1,OR2T4,NM_001004696,"""Homo sapiens olfactory receptor, family 2, subfamily T, member 4 (OR2T4), mRNA.""",RefSeq,3.692885,3.425188,2.554139,1.203885,0.005102,0.241424,up,coding,40 TC06000270.hg.1,HIST1H2BO,NM_003527,"""Homo sapiens histone cluster 1, H2bo (HIST1H2BO), mRNA.""",RefSeq,6.165679,6.54038,-2.394554,-1.296571,0.006829,0.611278,down,coding,41 TC14000089.hg.1,TRAV1-1,ENST00000542354,cdna:known chromosome:GRCh37:14:22089991:22090720:1 gene:ENSG00000255569 gene_biotype:TR_V_gene transcript_biotype:TR_V_gene,ENSEMBL,5.11064,4.847598,2.363507,1.200007,0.007306,0.278608,up,coding,42 TC11000118.hg.1,OR52N4,ENST00000317254,cdna:known chromosome:GRCh37:11:5775923:5776959:1 gene:ENSG00000181074 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,1.77049,2.099724,-2.250849,-1.256346,0.009165,0.63229,down,coding,43 TC06000176.hg.1,HIST1H2BH,BC096118,"""Homo sapiens histone cluster 1, H2bh, mRNA (cDNA clone MGC:116764 IMAGE:40002318), complete cds.""",GenBank,4.729625,5.068755,-2.177255,-1.264994,0.010542,0.63229,down,coding,44 TC05000767.hg.1,PCDHGB7,NM_032101,"""Homo sapiens protocadherin gamma subfamily B, 7 (PCDHGB7), transcript variant 2, mRNA.""",RefSeq,5.398327,5.665884,-2.094317,-1.203768,0.012614,0.63229,down,coding,45 TC14002240.hg.1,IGHD3-3,ENST00000390590,cdna:known chromosome:GRCh37:14:106380218:106380248:-1 gene:ENSG00000211930 gene_biotype:IG_D_gene transcript_biotype:IG_D_gene,ENSEMBL,2.496944,3.076456,-2.038446,-1.494344,0.014128,0.63229,down,coding,46 TC11000445.hg.1,OR8H2,NM_001005200,"""Homo sapiens olfactory receptor, family 8, subfamily H, member 2 (OR8H2), mRNA.""",RefSeq,2.696246,2.364396,1.840831,1.258626,0.021786,0.395935,up,coding,47 TC20000184.hg.1,DEFB118,NM_054112,"""Homo sapiens defensin, beta 118 (DEFB118), mRNA.""",RefSeq,4.176295,4.446238,-1.746506,-1.20576,0.02671,0.705156,down,coding,48 TC06000170.hg.1,HIST1H2BE,NM_003523,"""Homo sapiens histone cluster 1, H2be (HIST1H2BE), mRNA.""",RefSeq,2.145951,2.525029,-1.682174,-1.300511,0.030997,0.705156,down,coding,49 TC01002028.hg.1,OR2L3,NM_001004687,"""Homo sapiens olfactory receptor, family 2, subfamily L, member 3 (OR2L3), mRNA.""",RefSeq,3.814133,3.506981,1.660759,1.237263,0.032535,0.449671,up,coding,50 TC14001107.hg.1,,ENST00000358799,cdna:novel chromosome:GRCh37:14:50300810:50311552:-1 gene:ENSG00000197502 gene_biotype:protein_coding transcript_biotype:protein_coding,ENSEMBL,5.339718,5.645477,-1.637602,-1.236069,0.034184,0.705156,down,coding,51