Supporting information for West et al. (September 18, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.201162998.

Table 3. Complete listing of genes that provide estrogen receptor (ER) discrimination

ER rank

ER weight

Accession no.

Unigene cluster

Symbol

1

0.08

x52003

Trefoil factor 1 (pS2)

TFF1

2

0.079

x03635

Estrogen receptor 1

ESR1

3

0.067

m29874

Cytochrome P450, subfamily IIB

CYP2B

4

0.064

l08044

Trefoil factor 3

TFF3

5

0.061

s37730

(Insulin-like growth factor)

IGFBP2

6

0.057

u79293

Human clone 23948 mRNA sequence

N/A

7

0.056

j03778

Microtubule-associated protein t

MAPT

8

0.055

x07732

Hepsin

HPN

9

0.048

x58072

GATA-binding protein 3

GATA3

10

0.047

u22376

v-myb avian myeloblastosis viral oncogene homolog

MYB

11

-

 0.043

u04313

Serine proteinase inhibitor, clade B, member 5

SERPINB5

12

0.041

x17059

N

-acetyltransferase 1

NAT1

13

-

 0.041

m26311

S100 calcium-binding protein A9

S100A9

14

-

 0.041

u27185

Retinoic acid receptor responder 1

RARRES1

15

-

 0.039

u84487

Small inducible cytokine subfamily D, member 1

SCYD1

16

0.039

u39840

Hepatocyte nuclear factor 3a

HNF3A

17

0.038

u32907

37 kDa leucine-rich repeat (LRR) protein

P37NB

18

0.038

m35851

(Androgen receptor)

AR

19

-

 0.038

x87212

Cathepsin C

CTSC

20

0.037

u96922

Inositol polyphosphate-4-phosphatase, type II, 105 kDa

INPP4B

21

0.036

af000234

Purinergic receptor P2X, ligand-gated ion channel, 4

P2RX4

22

-

 0.036

d50915

KIAA0125 gene product

KIAA0125

23

0.036

l07615

(Neuropeptide Y receptor Y1)

NPY1R

24

0.035

u68385

Meis (mouse) homolog 3

MEIS3

25

0.035

u41060

LIV-1 protein, estrogen-regulated

LIV-1

26

0.034

hg3548-ht3749

(CCAAT displacement protein)

CUTL1

27

0.032

d38437

Postmeiotic segregation increased 2-like 3

PMS2L3

28

-

 0.031

x04470

Secretory leukocyte protease inhibitor

SLPI

29

0.029

m81057

Carboxypeptidase B1

CPB1

30

0.027

u95740

KIAA0430 gene product

KIAA0430

31

-

 0.027

m24485

Glutathione S-transferase p

GSTP1

32

0.025

x55037

GATA-binding protein 3

GATA3

33

0.023

m31627

X-box-binding protein 1

XBP1

34

-

 0.023

x13794

Lactate dehydrogenase B

LDHB

35

0.022

z29083

5T4 oncofetal trophoblast glycoprotein

5T4

36

0.022

u21931

(Fructose-1,6-biphosphatase)

FBP1

37

0.021

m23263

Androgen receptor

AR

38

0.021

u09770

Cysteine-rich protein 1

CRIP1

39

0.021

x13238

Cytochrome C oxidase subunit vic

COX6C

40

-

 0.02

u03057

Singed (Drosophila)-like

SNL

41

-

 0.019

u05340

CDC20

CDC20

42

-

 0.018

x01630

Argininosuccinate synthetase

ASS

43

-

 0.018

s45630

Crystallin, aB

CRYAB

44

-

 0.017

hg3494-ht3688

(Nuclear factor NF-IL6)

45

0.016

x83425

Lutheran blood group

LU

46

0.016

m14745

B-cell CLL/lymphoma 2

BCL2

47

-

 0.015

x87241

FAT tumor suppressor

FAT

48

0.015

m99701

Transcription elongation factor A (SII)-like 1

TCEAL1

49

0.015

hg3125-ht3301

(Estrogen receptor)

ESR1

50

0.015

x12876

Keratin 18

KRT18

51

0.015

u96113

(Nedd-4-like ubiquitin protein ligase)

WWP1

52

0.015

m27891

(Cystatin C)

CST3

53

-

 0.014

d63880

Chromosome condensation-related SMC-associated protein 1

KIAA0159

54

0.014

x68733

Serine proteinase inhibitor, clade A, member 3

SERPINA3

55

0.014

z23090

Heat-shock 27-kDa protein 1

HSPB1

56

0.014

x16665

Homeo box B2

HOXB2

57

0.014

m62403

Insulin-like growth factor-binding protein 4

IGFBP4

58

-

 0.014

u85193

Nuclear factor I/B

NFIB

59

0.013

z48633

Homo sapiens

 mRNA for RetroTransposon

N/A

60

0.013

d50840

UDP-glucose ceramide glucosyltransferase

UGCG

61

0.013

l15702

B-factor

BF

62

0.013

d78134

Cold inducible RNA-binding protein

CIRBP

63

0.013

u72649

BTG family, member 2

BTG2

64

0.012

x75861

Testis enhanced gene transcript

TEGT

65

0.012

u52100

Epithelial membrane protein 2

EMP2

66

0.011

x53002

Integrin, b5

ITGB5

67

0.011

u29656

Non-metastatic cells 3, protein expressed in

NME3

68

0.011

x59834

Glutamate-ammonia ligase

GLUL

69

0.011

l40401

Peroxisomal long-chain acyl-CoA thioesterase, putative protein

ZAP128

70

-

 0.011

m32313

Steroid-5-a-reductase, a polypeptide 1

SRD5A1

71

0.011

x57351

Interferon induced transmembrane protein 2

IFITM2

72

-

 0.011

d38550

Human mRNA for KIAA0075 gene

73

-

 0.01

d90209

Activating transcription factor 4

ATF4

74

0.01

u68142

RAB2, member of RAS oncogene family-like

RAB2L

75

0.01

s69272

Serine proteinase inhibitor, clade B, member 6

SERPINB6

76

-

 0.0099

m69066

Moesin

MSN

77

0.0091

hg1515-ht1515

(Transcription factor BTF3B)

BTF3

78

0.0091

u67963

Lysophospholipase-like

HU-K5

79

-

 0.0091

u65785

Oxygen regulated protein (150 kDa)

ORP150

80

0.0089

u09196

Polymerase (DNA-directed), d4

POLD4

81

0.0088

u11791

Cyclin H

CCNH

82

0.0086

m29877

Fucosidase, a-L-1, tissue

FUCA1

83

-

 0.0083

u96131

Thyroid hormone receptor interactor 13

TRIP13

84

0.0082

u14603

Protein tyrosine phosphatase type IVA, member 2

PTP4A2

85

-

 0.0079

m14328

Enolase 1

ENO1

86

0.0078

x74929

Keratin 8

KRT8

87

0.0078

x71973

Glutathione peroxidase 4

GPX4

88

0.0077

m74715

Iduronidase, a-L

IDUA

89

0.0076

u14394

Tissue inhibitor of metalloproteinase 3

TIMP3

90

0.0075

u30827

Splicing factor, arginine/serine-rich 5

SFRS5

91

0.0074

u79262

Deoxyhypusine synthase

DHPS

92

0.0071

u94831

Transmembrane 9 superfamily member 1

TM9SF1

93

-

 0.007

l20298

Core-binding factor, b subunit

CBFB

94

0.0069

u72066

Retinoblastoma-binding protein 8

RBBP8

95

-

 0.0068

l16862

G protein-coupled receptor kinase 6

GPRK6

96

-

 0.0066

m96982

U2(RNU2) small nuclear RNA auxilliary factor 1

U2AF1

97

-

 0.0066

u09564

SFRS protein kinase 1

SRPK1

98

0.0061

hg2238-ht2321

(Nuclear mitotic apparatus protein 1)

NUMA1

99

-

 0.0055

d86978

KIAA0225 protein

KIAA0225

100

0.0039

x91648

H. sapiens

 mRNA for pura extended 3' untranslated region

N/A