{"text_format":"2","workbook":"xlsx","n_sheets":3,"sheets":["Saccone","DrugBank Pharmactive Only","DrugBank All"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Saccone","index":0,"n_rows":137,"n_cols":10,"rows_kept":137,"cut":false,"hidden":false,"merged":[[1,0,1,9]]}
["Method of Saccone et al, 2007."]
["The P-value for each gene is determined by selecting the strongest P-value, then discounting it based on the number of SNPs in the gene."]
["The gene set used is the same as the main analysis."]
[]
[]
[]
[]
["Drug","Gene count","Genes on chip","SNP count","Combined p","Log p","Expected log(P)","Stdev of expected log(P)","Z","Adjusted P"]
["palonosetron",5,4,11,1.50045228813357E-2,1.82377780985575,0.72649746206001697,0.552611567120465,1.9856268183335699,2.3537388172151501E-2]
["granisetron",5,4,11,1.50045228813357E-2,1.82377780985575,0.72649746206001697,0.552611567120465,1.9856268183335699,2.3537388172151501E-2]
["dolasetron",5,4,11,1.50045228813357E-2,1.82377780985575,0.72649746206001697,0.552611567120465,1.9856268183335699,2.3537388172151501E-2]
["alosetron",5,4,11,1.50045228813357E-2,1.82377780985575,0.72649746206001697,0.552611567120465,1.9856268183335699,2.3537388172151501E-2]
["ondansetron",5,4,11,1.50045228813357E-2,1.82377780985575,0.72649746206001697,0.552611567120465,1.9856268183335699,2.3537388172151501E-2]
["nifedipine",5,5,38,2.2765726355105001E-2,1.6427184886906601,0.61542799477110899,0.54306057927893903,1.89166832047275,2.9267593382922799E-2]
["prazosin",3,2,7,1.21922088569717E-2,1.9139176063183301,1.00841736356801,0.62914067549909503,1.4392651405537999,7.5037707737582504E-2]
["labetalol",5,4,14,3.1703833073202799E-2,1.4988882273120701,0.72649746206001697,0.552611567120465,1.3977100936862601,8.1100070975167901E-2]
["carvedilol",5,4,14,3.1703833073202799E-2,1.4988882273120701,0.72649746206001697,0.552611567120465,1.3977100936862601,8.1100070975167901E-2]
["memantine",6,2,17,1.6594947121278E-2,1.78002412710435,1.00841736356801,0.62914067549909503,1.2264455209865801,0.11001553234596601]
["sildenafil",1,1,3,1.4550680796E-2,1.83711668646987,1.0768608534178801,0.62500341669349102,1.2164026831629799,0.11191578117713499]
["tadalafil",1,1,3,1.4550680796E-2,1.83711668646987,1.0768608534178801,0.62500341669349102,1.2164026831629799,0.11191578117713499]
["gabapentin",7,5,9,6.9941273954974695E-2,1.1552664614380199,0.61542799477110899,0.54306057927893903,0.994066752890997,0.16009518510682799]
["clofibrate",1,1,4,2.48620640237006E-2,1.6044628195039501,1.0768608534178801,0.62500341669349102,0.84415853096817905,0.199290412022474]
["digoxin",8,5,13,0.103203963817634,0.98630362217521195,0.61542799477110899,0.54306057927893903,0.68293601405673898,0.24732363783222]
["agomelatine",3,2,4,3.8428219213762403E-2,1.4153497405305899,1.00841736356801,0.62914067549909503,0.64680665677793403,0.25887854177165198]
["mexiletine",1,1,12,4.6158127733852E-2,1.3357518153494401,1.0768608534178801,0.62500341669349102,0.41422327465215503,0.33935529899630101]
["glyburide",3,3,13,8.4295244654471704E-2,1.0741969245279701,0.86527001370372703,0.60187472042291801,0.34712690820016501,0.36424798954450299]
["trazodone",6,5,12,0.163808291376009,0.78566411962252003,0.61542799477110899,0.54306057927893903,0.31347538625883298,0.37695975896802902]
["metoclopramide",9,8,28,0.35748342832555702,0.44674408576101798,0.34199854200276603,0.40920211923493099,0.25597507645876899,0.39898504120880401]
["metformin",7,3,9,0.123631079235688,0.90787233957190705,0.86527001370372703,0.60187472042291801,7.0782713449477494E-2,0.47178534499049302]
["dipyridamole",13,9,38,0.54910186179787301,0.26034708375889498,0.26828294304596501,0.35134629858646699,-2.2587001254882E-2,0.509010143660097]
["omalizumab",4,3,10,0.15553001894621801,0.80818577509715195,0.86527001370372703,0.60187472042291801,-9.4844054201950301E-2,0.53778065281373499]
["amitriptyline",7,7,18,0.42815622643018703,0.36839773590096198,0.41789328841536799,0.44449027943458802,-0.111353509411647,0.54433198758784496]
["theophylline",29,21,104,0.99918843954859604,3.52599322968745E-4,1.77261680335206E-2,0.119091132408313,-0.145884654543255,0.55799377705972497]
["caffeine",27,21,104,0.99918843954859604,3.52599322968745E-4,1.77261680335206E-2,0.119091132408313,-0.145884654543255,0.55799377705972497]
["pentoxifylline",12,9,53,0.636471885143292,0.19622077566594601,0.26828294304596501,0.35134629858646699,-0.205102964425523,0.58125415980306605]
["carglumic acid",2,1,8,0.12062023900505101,0.91857981532392796,1.0768608534178801,0.62500341669349102,-0.25324827651554899,0.59996181859523701]
["acetaminophen",2,1,6,0.12962614706575701,0.88730738750068505,1.0768608534178801,0.62500341669349102,-0.303283887502583,0.61916323789477501]
["dextromethorphan",5,4,24,0.282738213309152,0.54861549074022897,0.72649746206001697,0.552611567120465,-0.32189331874953497,0.62623324254944102]
["bromocriptine",2,2,9,0.15816765288840001,0.80088232999435804,1.00841736356801,0.62914067549909503,-0.32987063411377598,0.62925114337819399]
["cabergoline",4,2,9,0.15816765288840001,0.80088232999435804,1.00841736356801,0.62914067549909503,-0.32987063411377598,0.62925114337819399]
["methadone",4,4,23,0.28667162047723899,0.54261529861327795,0.72649746206001697,0.552611567120465,-0.33275120244932199,0.63033895208294299]
["bisoprolol",2,2,7,0.19604837955179999,0.70763674303283597,1.00841736356801,0.62914067549909503,-0.47808166320921602,0.68370395866852696]
["propranolol",2,2,7,0.19604837955179999,0.70763674303283597,1.00841736356801,0.62914067549909503,-0.47808166320921602,0.68370395866852696]
["lidocaine",3,3,28,0.276717713038167,0.55796304025001298,0.86527001370372703,0.60187472042291801,-0.51058295526647102,0.69517844323361899]
["prochlorperazine",5,4,14,0.40421587979632201,0.39338662903830801,0.72649746206001697,0.552611567120465,-0.60279381185861702,0.72667706803944399]
["chlormethiazole",15,10,51,0.99786831073105198,9.2676902975282198E-4,0.217159196525128,0.344724446313174,-0.62726165726852201,0.73475613365168502]
["chloral hydrate",15,10,51,0.99786831073105198,9.2676902975282198E-4,0.217159196525128,0.344724446313174,-0.62726165726852201,0.73475613365168502]
["tranexamic acid",2,2,7,0.26141268267390599,0.58267334605280496,1.00841736356801,0.62914067549909503,-0.67670718822538001,0.750704122591902]
["sapropterin",7,5,15,0.57646859335992295,0.239224348563605,0.61542799477110899,0.54306057927893903,-0.69274710881613899,0.75576586508712895]
["lansoprazole",1,1,1,0.24349999999999999,0.61350103444934601,1.0768608534178801,0.62500341669349102,-0.741371657486114,0.77076593775881697]
["rabeprazole",1,1,1,0.24349999999999999,0.61350103444934601,1.0768608534178801,0.62500341669349102,-0.741371657486114,0.77076593775881697]
["omeprazole",1,1,1,0.24349999999999999,0.61350103444934601,1.0768608534178801,0.62500341669349102,-0.741371657486114,0.77076593775881697]
["pantoprazole",1,1,1,0.24349999999999999,0.61350103444934601,1.0768608534178801,0.62500341669349102,-0.741371657486114,0.77076593775881697]
["doxepin",13,9,19,0.99949364065247603,2.19964765798195E-4,0.26828294304596501,0.35134629858646699,-0.762959448722344,0.77725620988064104]
["isoprenaline",3,3,9,0.398743136651244,0.399306779145156,0.86527001370372703,0.60187472042291801,-0.77418641911252495,0.78058972085077505]
["hydralazine",2,1,2,0.31760379122462801,0.49811432205694101,1.0768608534178801,0.62500341669349102,-0.92598938806244502,0.82277425242070901]
["opium alkaloids",1,1,10,0.355104902875507,0.44964333142387197,1.0768608534178801,0.62500341669349102,-1.0035425491147401,0.84220042092319203]
["dihydrocodeine",1,1,10,0.355104902875507,0.44964333142387197,1.0768608534178801,0.62500341669349102,-1.0035425491147401,0.84220042092319203]
["methylnaltrexone",1,1,10,0.355104902875507,0.44964333142387197,1.0768608534178801,0.62500341669349102,-1.0035425491147401,0.84220042092319203]
["diphenoxylate",1,1,10,0.355104902875507,0.44964333142387197,1.0768608534178801,0.62500341669349102,-1.0035425491147401,0.84220042092319203]
["isosorbide dinitrate",4,3,9,0.58605348976166605,0.23206274362667001,0.86527001370372703,0.60187472042291801,-1.05205825829023,0.85361358919408004]
["methyldopa",4,2,8,0.45948313690715997,0.337730422651219,1.00841736356801,0.62914067549909503,-1.06603652733904,0.85679643492116797]
["alglucosidase alfa",2,1,7,0.39565718500188701,0.40268094322261,1.0768608534178801,0.62500341669349102,-1.0786819594714301,0.85963523468968195]
["benzhexol",1,1,2,0.41534168654845899,0.38159447792117801,1.0768608534178801,0.62500341669349102,-1.11242011951699,0.86702122100512502]
["mepolizumab",3,2,7,0.50115078319985895,0.30003158658901402,1.00841736356801,0.62914067549909503,-1.12595768254379,0.86990828412934396]
["insulin lispro",1,1,8,0.42758859646999098,0.36897388568074302,1.0768608534178801,0.62500341669349102,-1.1326129567133101,0.87131158742853798]
["insulin aspart",1,1,8,0.42758859646999098,0.36897388568074302,1.0768608534178801,0.62500341669349102,-1.1326129567133101,0.87131158742853798]
["insulin detemir",1,1,8,0.42758859646999098,0.36897388568074302,1.0768608534178801,0.62500341669349102,-1.1326129567133101,0.87131158742853798]
["isoniazid",5,3,10,0.659447082354637,0.180820048887056,0.86527001370372703,0.60187472042291801,-1.13719673146552,0.87227197347535301]
["desipramine",3,3,7,0.66168809919618199,0.17934667629777701,0.86527001370372703,0.60187472042291801,-1.13964470367516,0.87278282345587199]
["pizotifen",2,2,5,0.52044931429236796,0.28362155932344002,1.00841736356801,0.62914067549909503,-1.1520409225958801,0.87534787120653101]
["atropine",5,3,7,0.692853601448991,0.15935852123171301,0.86527001370372703,0.60187472042291801,-1.1728545302185001,0.87957292686510902]
["promethazine",3,3,10,0.70430916884052197,0.15223665783665399,0.86527001370372703,0.60187472042291801,-1.18468733055617,0.88192945321908001]
["nortriptyline",4,4,9,0.86581889170443405,6.2572942346517404E-2,0.72649746206001697,0.552611567120465,-1.2014307322104401,0.88520791956505296]
["ephedrine",1,1,3,0.47422998999999999,0.32401098498525899,1.0768608534178801,0.62500341669349102,-1.2045532045496501,0.88581208447711901]
["reboxetine",1,1,3,0.47422998999999999,0.32401098498525899,1.0768608534178801,0.62500341669349102,-1.2045532045496501,0.88581208447711901]
["cyproheptadine",3,3,7,0.73780490848167102,0.13205845981751901,0.86527001370372703,0.60187472042291801,-1.21821290877776,0.88842846229093897]
["lurasidone",5,3,9,0.73921984046096001,0.13122638528486599,0.86527001370372703,0.60187472042291801,-1.21959538008685,0.88869085068577203]
["doxylamine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["nortryptiline",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["triprolidine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["cetirizine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["clemastine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["brompheniramine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["meclizine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["hydroxyzine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["fexofenadine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["chlorpheniramine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["loratadine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["diphenhydramine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["pheniramine",1,1,2,0.51252000104209405,0.290289181642511,1.0768608534178801,0.62500341669349102,-1.25850779494397,0.895895915032623]
["chloroquine",7,4,8,0.933071317783286,3.0085160394946301E-2,0.72649746206001697,0.552611567120465,-1.26022027605017,0.89620504481259999]
["duloxetine",2,2,4,0.61071105287251604,0.214164219912264,1.00841736356801,0.62914067549909503,-1.2624412545344801,0.896604973830047]
["venlafaxine",2,2,4,0.61071105287251604,0.214164219912264,1.00841736356801,0.62914067549909503,-1.2624412545344801,0.896604973830047]
["imipramine",2,2,4,0.61071105287251604,0.214164219912264,1.00841736356801,0.62914067549909503,-1.2624412545344801,0.896604973830047]
["mirtazapine",5,3,6,0.79888497622516597,9.7515746076168197E-2,0.86527001370372703,0.60187472042291801,-1.2756047755055699,0.89895236743574802]
["buspirone",2,2,6,0.63755384959730599,0.19548312760728301,1.00841736356801,0.62914067549909503,-1.2921342835063601,0.90184467749213004]
["oxybutynin",3,2,5,0.67061623135530102,0.173525939271749,1.00841736356801,0.62914067549909503,-1.3270345676409301,0.90775137594087196]
["procyclidine",4,2,5,0.67061623135530102,0.173525939271749,1.00841736356801,0.62914067549909503,-1.3270345676409301,0.90775137594087196]
["evolocumab",1,1,6,0.56622655744925199,0.247009764990028,1.0768608534178801,0.62500341669349102,-1.3277544830364001,0.907870385886834]
["codeine",3,2,12,0.67377121033938803,0.17148754998573901,1.00841736356801,0.62914067549909503,-1.3302745255158399,0.90828608134919897]
["naloxone",3,2,12,0.67377121033938803,0.17148754998573901,1.00841736356801,0.62914067549909503,-1.3302745255158399,0.90828608134919897]
["oxycodone",3,2,12,0.67377121033938803,0.17148754998573901,1.00841736356801,0.62914067549909503,-1.3302745255158399,0.90828608134919897]
["triamcinolone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["cortisone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["betamethasone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["methylprednisolone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["hydrocortisone",2,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["prednisolone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["prednisone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["dexamethasone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["beclomethasone",1,1,2,0.62155601845451403,0.20651972396629401,1.0768608534178801,0.62500341669349102,-1.3925381945206401,0.91812025799327202]
["calcium carbimide",3,2,8,0.75525282758975198,0.121907640097279,1.00841736356801,0.62914067549909503,-1.40908028680146,0.920594285404152]
["ticlopidine",1,1,4,0.65225083759484703,0.185585354523507,1.0768608534178801,0.62500341669349102,-1.4260330025227099,0.92307059200131403]
["prasugrel",1,1,4,0.65225083759484703,0.185585354523507,1.0768608534178801,0.62500341669349102,-1.4260330025227099,0.92307059200131403]
["epoprostenol",3,1,4,0.65225083759484703,0.185585354523507,1.0768608534178801,0.62500341669349102,-1.4260330025227099,0.92307059200131403]
["clopidogrel",1,1,4,0.65225083759484703,0.185585354523507,1.0768608534178801,0.62500341669349102,-1.4260330025227099,0.92307059200131403]
["galantamine",4,3,6,0.98869117484273294,4.9393423829587699E-3,0.86527001370372703,0.60187472042291801,-1.42941818642298,0.92355796282970204]
["anakinra",2,2,6,0.83097419679150597,8.0412461613059205E-2,1.00841736356801,0.62914067549909503,-1.4750356130109801,0.92989851543162205]
["bupropion",2,2,5,0.83995927162108597,7.5741771722698401E-2,1.00841736356801,0.62914067549909503,-1.48245953276733,0.93089096824230599]
["sumatriptan",4,2,4,0.847422948820305,7.1899779170203501E-2,1.00841736356801,0.62914067549909503,-1.4885662632683401,0.93169918950380404]
["clonidine",3,1,2,0.73410310198311801,0.13424294079531701,1.0768608534178801,0.62500341669349102,-1.5081804154117699,0.93424582085486396]
["eletriptan",4,2,4,0.92047613890185898,3.5987465038910503E-2,1.00841736356801,0.62914067549909503,-1.5456477961112201,0.938905174339282]
["rizatriptan",4,2,4,0.92047613890185898,3.5987465038910503E-2,1.00841736356801,0.62914067549909503,-1.5456477961112201,0.938905174339282]
["maraviroc",1,1,5,0.811571832163,9.0673034763957799E-2,1.0768608534178801,0.62500341669349102,-1.5778918839695899,0.94270477507705597]
["tirofiban",2,2,3,0.96779811215339695,1.4215229388132499E-2,1.00841736356801,0.62914067549909503,-1.58025410356941,0.942975657000376]
["corticotrophin",1,0,0,"N/A"]
["ranitidine",1,0,0,"N/A"]
["zafirlukast",1,0,0,"N/A"]
["erythromycin",1,0,0,"N/A"]
["dimethyl fumarate",2,0,0,"N/A"]
["cimetidine",1,0,0,"N/A"]
["nizatidine",1,0,0,"N/A"]
["aprepitant",1,0,0,"N/A"]
["famotidine",1,0,0,"N/A"]
["meperidine",1,0,0,"N/A"]
["montelukast",1,0,0,"N/A"]

{"sheet":"DrugBank Pharmactive Only","index":1,"n_rows":119,"n_cols":10,"rows_kept":119,"cut":false,"hidden":false,"merged":[[1,0,1,9],[2,0,2,9],[3,0,3,9]]}
["DrugBank Pharmactive Only"]
["The statistical analysis is the same as used for the main analysis."]
["The gene sets are those defined by the DrugBank \"Pharmacologically Active\" dataset."]
["Note that 5-HT3 antagonists are no longer ranked as their only targeted gene in this set (HTR3A) is not represented on our genotyping chip."]
[]
[]
[]
[]
["Drug","Gene count","Genes on chip","SNP count","Combined p","Log p","Expected log(P)","Stdev of expected log(P)","Z","Adjusted P"]
["nifedipine",5,5,38,2.9256161151429799E-5,4.53378266044332,1.4233947391639501,0.86030645440318498,3.6154418060679498,1.4991791338814201E-4]
["memantine",3,2,17,7.2829538434457505E-4,3.1376924424280301,0.97786358739417001,0.65537118444544396,3.29558104825961,4.9109183789475199E-4]
["carvedilol",2,2,7,9.9462012586776401E-4,3.0023427571841399,0.97786358739417001,0.65537118444544396,3.0890573431345301,1.00396339647024E-3]
["dextromethorphan",2,1,10,2.5040000000000001E-3,2.6013656754615999,0.80941592308412103,0.58641420982642201,3.0557747789022698,1.12239903393152E-3]
["prazosin",3,2,7,2.4327252150715098E-3,2.6139069433986899,0.97786358739417001,0.65537118444544396,2.4963614434602999,6.2737338515370597E-3]
["pentoxifylline",5,3,15,1.03356717058855E-3,2.9856612937168898,1.1427850331257201,0.74354699752386699,2.4784933120949302,6.5969292294040197E-3]
["gabapentin",3,2,3,2.7372541713372601E-3,2.5626848737319601,0.97786358739417001,0.65537118444544396,2.4182041016631302,7.7986626883458296E-3]
["theophylline",8,4,25,6.97586713319199E-4,3.1564017998459901,1.27372904713085,0.79800268107877603,2.3592311120685099,9.1564234076465505E-3]
["labetalol",5,4,14,7.2136176254055404E-4,3.1418468821975201,1.27372904713085,0.79800268107877603,2.3409919281740499,9.6162914577376801E-3]
["mexiletine",1,1,12,7.2439999999999996E-3,2.14002155835797,0.80941592308412103,0.58641420982642201,2.2690542162470999,1.1632514542888399E-2]
["sildenafil",1,1,3,7.3019999999999899E-3,2.13655817138629,0.80941592308412103,0.58641420982642201,2.2631481742145998,1.18132783674467E-2]
["tadalafil",1,1,3,7.3019999999999899E-3,2.13655817138629,0.80941592308412103,0.58641420982642201,2.2631481742145998,1.18132783674467E-2]
["clofibrate",1,1,4,1.0019999999999999E-2,1.99913227846877,0.80941592308412103,0.58641420982642201,2.0287986468417998,2.1239401594929E-2]
["dipyridamole",4,4,19,1.5890571136228601E-3,2.7988604931730499,1.27372904713085,0.79800268107877603,1.9111858671708299,2.7990349712825501E-2]
["omalizumab",2,2,6,8.0635950373935603E-3,2.09347129109715,0.97786358739417001,0.65537118444544396,1.70225321189087,4.43539557813524E-2]
["glyburide",1,1,6,2.1409999999999998E-2,1.6693833327055601,0.80941592308412103,0.58641420982642201,1.4664846028816201,7.1258156413857895E-2]
["agomelatine",3,2,4,1.43621898850976E-2,1.8427793356853699,0.97786358739417001,0.65537118444544396,1.31973417327322,9.3461893106876498E-2]
["carglumic acid",1,1,8,2.8160000000000001E-2,1.5503673495299199,0.80941592308412103,0.58641420982642201,1.26352911309077,0.10319954537786]
["lidocaine",3,3,28,9.2982513108805596E-3,2.03159871998841,1.1427850331257201,0.74354699752386699,1.1953698822301499,0.11597127370735701]
["bromocriptine",2,2,9,2.0194574133760301E-2,1.6947653008652701,0.97786358739417001,0.65537118444544396,1.0938865340527899,0.13700237268918]
["acetaminophen",2,1,6,3.8890000000000001E-2,1.4101620568525399,0.80941592308412103,0.58641420982642201,1.0244399329038001,0.15281376430641699]
["methadone",4,4,23,9.9839457854728007E-3,2.0006977859482999,1.27372904713085,0.79800268107877603,0.91098533382706703,0.18115155063594399]
["diphenoxylate",1,1,10,7.6660000000000006E-2,1.1154311850816601,0.80941592308412103,0.58641420982642201,0.521841484857819,0.30089035138397702]
["methylnaltrexone",1,1,10,7.6660000000000006E-2,1.1154311850816601,0.80941592308412103,0.58641420982642201,0.521841484857819,0.30089035138397702]
["digoxin",1,1,1,0.10580000000000001,0.97551433230083295,0.80941592308412103,0.58641420982642201,0.28324417524922602,0.38849483364243498]
["insulin aspart",1,1,8,0.116599999999999,0.93330144957700401,0.80941592308412103,0.58641420982642201,0.21125942110023799,0.41634242277969802]
["insulin detemir",1,1,8,0.116599999999999,0.93330144957700401,0.80941592308412103,0.58641420982642201,0.21125942110023799,0.41634242277969802]
["insulin lispro",1,1,8,0.116599999999999,0.93330144957700401,0.80941592308412103,0.58641420982642201,0.21125942110023799,0.41634242277969802]
["mirtazapine",3,1,3,0.11799999999999999,0.92811799269387396,0.80941592308412103,0.58641420982642201,0.20242017949204999,0.41979412698323099]
["isoprenaline",3,3,9,5.4376349915243698E-2,1.2645899483644001,1.1427850331257201,0.74354699752386699,0.16381602729122299,0.43493798708736298]
["lurasidone",2,2,8,8.6522978274529996E-2,1.06286853978851,0.97786358739417001,0.65537118444544396,0.129705050224737,0.44839989341166497]
["cabergoline",1,1,5,0.14459999999999901,0.83983170704148802,0.80941592308412103,0.58641420982642201,5.1867406088897103E-2,0.47931717273809199]
["prochlorperazine",1,1,5,0.14459999999999901,0.83983170704148802,0.80941592308412103,0.58641420982642201,5.1867406088897103E-2,0.47931717273809199]
["codeine",3,2,12,0.101998483280084,0.99140628615952797,0.97786358739417001,0.65537118444544396,2.0664165722844199E-2,0.49175677726143502]
["naloxone",3,2,12,0.101998483280084,0.99140628615952797,0.97786358739417001,0.65537118444544396,2.0664165722844199E-2,0.49175677726143502]
["oxycodone",3,2,12,0.101998483280084,0.99140628615952797,0.97786358739417001,0.65537118444544396,2.0664165722844199E-2,0.49175677726143502]
["bisoprolol",1,1,2,0.15809999999999899,0.80106813006779098,0.80941592308412103,0.58641420982642201,-1.42353184429161E-2,0.50567887860248795]
["propranolol",1,1,2,0.15809999999999899,0.80106813006779098,0.80941592308412103,0.58641420982642201,-1.42353184429161E-2,0.50567887860248795]
["hydralazine",1,1,2,0.22489999999999999,0.64801054456436702,0.80941592308412103,0.58641420982642201,-0.27524124725341997,0.60843455022972903]
["anakinra",1,1,2,0.2364,0.62635252779078199,0.80941592308412103,0.58641420982642201,-0.31217421444736998,0.62254593626894394]
["isosorbide dinitrate",1,1,3,0.2379,0.62360555796273298,0.80941592308412103,0.58641420982642201,-0.316858565170832,0.624324538305573]
["lansoprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412103,0.58641420982642201,-0.33408959972638602,0.63084402607310897]
["omeprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412103,0.58641420982642201,-0.33408959972638602,0.63084402607310897]
["pantoprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412103,0.58641420982642201,-0.33408959972638602,0.63084402607310897]
["rabeprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412103,0.58641420982642201,-0.33408959972638602,0.63084402607310897]
["metoclopramide",2,2,7,0.17985871043853599,0.74506852474128205,0.97786358739417001,0.65537118444544396,-0.35521101351117901,0.63878424277260903]
["reboxetine",1,1,3,0.27489999999999998,0.560825260156531,0.80941592308412103,0.58641420982642201,-0.423916506049831,0.66418664702904795]
["atropine",5,3,7,0.18078227174196501,0.742844160487523,1.1427850331257201,0.74354699752386699,-0.537882439133057,0.70467089359500701]
["clopidogrel",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412103,0.58641420982642201,-0.59127352370735098,0.72283141674535001]
["epoprostenol",3,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412103,0.58641420982642201,-0.59127352370735098,0.72283141674535001]
["prasugrel",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412103,0.58641420982642201,-0.59127352370735098,0.72283141674535001]
["ticlopidine",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412103,0.58641420982642201,-0.59127352370735098,0.72283141674535001]
["amitriptyline",3,3,7,0.21283470680834199,0.67195755050146699,1.1427850331257201,0.74354699752386699,-0.63321818821431197,0.73670441505255402]
["desipramine",3,3,7,0.21283470680834199,0.67195755050146699,1.1427850331257201,0.74354699752386699,-0.63321818821431197,0.73670441505255402]
["nortriptyline",3,3,7,0.21283470680834199,0.67195755050146699,1.1427850331257201,0.74354699752386699,-0.63321818821431197,0.73670441505255402]
["oxybutynin",3,2,5,0.28549784398245498,0.54439716710309904,0.97786358739417001,0.65537118444544396,-0.66140597966304704,0.74582400391624204]
["procyclidine",4,2,5,0.28549784398245498,0.54439716710309904,0.97786358739417001,0.65537118444544396,-0.66140597966304704,0.74582400391624204]
["brompheniramine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["clemastine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["diphenhydramine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["doxylamine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["fexofenadine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["hydroxyzine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["loratadine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["meclizine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["pheniramine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["promethazine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["triprolidine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412103,0.58641420982642201,-0.66486231148888497,0.746930718288909]
["sapropterin",4,2,4,0.29129857612527998,0.53566163820942403,0.97786358739417001,0.65537118444544396,-0.67473511146042198,0.75007796360944901]
["buspirone",2,2,6,0.322016350815584,0.4921220758548,0.97786358739417001,0.65537118444544396,-0.74117007745830299,0.77070483807572598]
["maraviroc",1,1,5,0.42670000000000002,0.36987735714068698,0.80941592308412103,0.58641420982642201,-0.74953600812902499,0.77323289799298001]
["eletriptan",3,1,3,0.42699999999999999,0.36957212497497499,0.80941592308412103,0.58641420982642201,-0.75005651421601505,0.773389665808347]
["rizatriptan",3,1,3,0.42699999999999999,0.36957212497497499,0.80941592308412103,0.58641420982642201,-0.75005651421601505,0.773389665808347]
["cyproheptadine",3,3,7,0.27925394930540698,0.55400067622697302,1.1427850331257201,0.74354699752386699,-0.79185896635921704,0.78577854232997302]
["betamethasone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["dexamethasone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["hydrocortisone",2,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["methylprednisolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["prednisolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["prednisone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["triamcinolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412103,0.58641420982642201,-0.83175366770303105,0.79722599948149198]
["duloxetine",2,2,4,0.39438719709938702,0.40407719190358798,0.97786358739417001,0.65537118444544396,-0.87551361596116395,0.80935274753682296]
["imipramine",2,2,4,0.39438719709938702,0.40407719190358798,0.97786358739417001,0.65537118444544396,-0.87551361596116395,0.80935274753682296]
["venlafaxine",2,2,4,0.39438719709938702,0.40407719190358798,0.97786358739417001,0.65537118444544396,-0.87551361596116395,0.80935274753682296]
["tranexamic acid",1,1,4,0.56840000000000002,0.24534593074456701,0.80941592308412103,0.58641420982642201,-0.96189686894953796,0.83194929423459796]
["clonidine",3,1,2,0.58650000000000002,0.23173198354845101,0.80941592308412103,0.58641420982642201,-0.98511245098692801,0.83771558095231402]
["bupropion",2,2,5,0.48635659849032398,0.31304518759461197,0.97786358739417001,0.65537118444544396,-1.0144150606226401,0.84480762957045097]
["galantamine",1,1,2,0.73040000000000005,0.136439235473757,0.80941592308412103,0.58641420982642201,-1.1476131995668399,0.874435860858367]
["trazodone",4,4,7,0.44769515947593502,0.34901760122579101,1.27372904713085,0.79800268107877603,-1.15878237984739,0.87672754925011998]
["sumatriptan",4,2,4,0.64251101829243196,0.19211942030394599,0.97786358739417001,0.65537118444544396,-1.1989299892016101,0.88472241518827599]
["doxepin",13,9,19,0.267258191992718,0.573068973929447,1.9234778359462099,0.995029657393528,-1.3571543842764899,0.91263391934974103]
["tirofiban",2,2,3,0.85430192553261297,6.8388614768670697E-2,0.97786358739417001,0.65537118444544396,-1.38772499342501,0.91738959882802595]
["alglucosidase alfa",1,0,0,"N/A"]
["alosetron",1,0,0,"N/A"]
["aprepitant",1,0,0,"N/A"]
["caffeine",2,0,0,"N/A"]
["cimetidine",1,0,0,"N/A"]
["dimethyl fumarate",1,0,0,"N/A"]
["dolasetron",1,0,0,"N/A"]
["famotidine",1,0,0,"N/A"]
["granisetron",1,0,0,"N/A"]
["mepolizumab",1,0,0,"N/A"]
["metformin",1,0,0,"N/A"]
["methyldopa",1,0,0,"N/A"]
["montelukast",1,0,0,"N/A"]
["nizatidine",1,0,0,"N/A"]
["ondansetron",1,0,0,"N/A"]
["palonosetron",1,0,0,"N/A"]
["ranitidine",1,0,0,"N/A"]
["zafirlukast",1,0,0,"N/A"]

{"sheet":"DrugBank All","index":2,"n_rows":140,"n_cols":10,"rows_kept":140,"cut":false,"hidden":false,"merged":[]}
["DrugBank All"]
["The statistical analysis is the same as used for the main analysis."]
["The gene sets are defined in DrugBank, including those not directly linked to drug mechanism of action."]
[]
[]
[]
[]
["Drug","Gene count","Genes on chip","SNP count","Combined p","Log p","Expected log(P)","Stdev of expected log(P)","Z","Adjusted P"]
["gabapentin",11,5,31,2.3111455985866801E-5,4.6361726937805399,1.4233947391639401,0.86030645440318698,3.7344575740110599,9.4060099502413203E-5]
["pentoxifylline",6,4,19,1.13928561571685E-4,3.9433673858593798,1.27372904713086,0.79800268107877703,3.3454002123395998,4.10819593469891E-4]
["caffeine",32,27,148,3.2549574914246799E-9,8.4874546787886391,4.0176543293862199,1.5473400187786399,2.8886995069968799,1.9341927342060299E-3]
["tadalafil",2,2,13,1.9494038891327799E-3,2.7100981718369699,0.97786358739417201,0.65537118444544296,2.6431351050451899,4.1071125599467699E-3]
["nifedipine",8,7,52,1.2375292598344401E-4,3.9074445239221398,1.6548982762948301,0.91844158471812498,2.4525743227519698,7.0919037450953796E-3]
["theophylline",8,4,25,6.97586713319199E-4,3.1564017998459901,1.27372904713086,0.79800268107877703,2.3592311120685001,9.1564234076467708E-3]
["labetalol",5,4,14,7.2136176254055404E-4,3.1418468821975201,1.27372904713086,0.79800268107877703,2.3409919281740401,9.6162914577377894E-3]
["sildenafil",3,1,3,7.3019999999999899E-3,2.13655817138629,0.80941592308412302,0.58641420982642201,2.2631481742145998,1.1813278367446899E-2]
["clofibrate",1,1,4,1.0019999999999999E-2,1.99913227846877,0.80941592308412302,0.58641420982642201,2.0287986468417998,2.1239401594929298E-2]
["dipyridamole",4,4,19,1.5890571136228601E-3,2.7988604931730499,1.27372904713086,0.79800268107877703,1.91118586717082,2.7990349712826101E-2]
["omalizumab",2,2,6,8.0635950373935603E-3,2.09347129109715,0.97786358739417201,0.65537118444544296,1.70225321189087,4.4353955781352497E-2]
["mexiletine",2,2,16,8.91102384534136E-3,2.05007239418571,0.97786358739417201,0.65537118444544296,1.6360328806626001,5.0916353010594398E-2]
["memantine",7,4,24,2.8406931488812702E-3,2.5465756761485601,1.27372904713086,0.79800268107877703,1.5950405420906599,5.53515850132257E-2]
["lidocaine",4,4,34,3.3784170887359898E-3,2.4712867348258101,1.27372904713086,0.79800268107877703,1.50069381480778,6.6717386794389502E-2]
["ephedrine",4,3,10,6.2303200457746498E-3,2.2054896434622,1.1427850331257099,0.74354699752386699,1.4292366371937,7.6468115374979398E-2]
["carvedilol",16,8,29,7.29622984433548E-4,3.1369014934084798,1.7966974637203299,0.97329023361563904,1.37698292184591,8.4258763998893801E-2]
["clonidine",6,3,9,7.45408697992245E-3,2.1276055438762498,1.1427850331257099,0.74354699752386699,1.32448993006514,9.2670192615774902E-2]
["agomelatine",3,2,4,1.43621898850976E-2,1.8427793356853699,0.97786358739417201,0.65537118444544296,1.31973417327322,9.3461893106876803E-2]
["chloroquine",4,3,6,7.8064777160847098E-3,2.1075448756641202,1.1427850331257099,0.74354699752386699,1.29751023909882,9.7227842203410506E-2]
["carglumic acid",1,1,8,2.8160000000000001E-2,1.5503673495299199,0.80941592308412302,0.58641420982642201,1.26352911309076,0.103199545377861]
["glyburide",10,8,45,9.8459555509530609E-4,3.00674212915836,1.7966974637203299,0.97329023361563904,1.2432516259234201,0.106887561966473]
["folic acid",2,1,4,3.3410000000000002E-2,1.47612352436186,0.80941592308412302,0.58641420982642201,1.13692265655549,0.12778530990624301]
["promethazine",10,7,22,2.2524857333570498E-3,2.64733795104542,1.6548982762948301,0.91844158471812498,1.0805691850888699,0.13994439798820299]
["acetaminophen",2,1,6,3.8890000000000001E-2,1.4101620568525399,0.80941592308412302,0.58641420982642201,1.0244399329038001,0.15281376430641799]
["prazosin",8,6,21,3.4684132761144499E-3,2.4598691600878402,1.5454408008517999,0.89726299970338497,1.0191308005995201,0.154070436693346]
["methadone",5,4,23,9.9839457854728197E-3,2.0006977859482999,1.27372904713086,0.79800268107877703,0.91098533382705904,0.18115155063594601]
["methyldopa",2,1,6,5.4429999999999999E-2,1.26416166568292,0.80941592308412302,0.58641420982642201,0.77546849134745,0.21903143851437601]
["bisoprolol",2,2,7,3.3293214082831597E-2,1.4776442766048501,0.97786358739417201,0.65537118444544296,0.762591796942651,0.222853439121935]
["cabergoline",20,11,34,1.1829344698628199E-3,2.9270393129927199,2.1808035867448599,1.09640096607057,0.68062301050528495,0.248055031533255]
["mirtazapine",22,12,36,1.0492149118589301E-3,2.97913554567219,2.2949561095837301,1.13915581201622,0.60060215544835405,0.27405250099496498]
["methylnaltrexone",2,1,10,7.6660000000000006E-2,1.1154311850816601,0.80941592308412302,0.58641420982642201,0.52184148485781601,0.30089035138397902]
["naloxone",6,4,28,2.5132679779694599E-2,1.5997612021560901,1.27372904713086,0.79800268107877703,0.40856022511664503,0.34143121251145803]
["bromocriptine",18,9,27,4.8598219296944502E-3,2.3133796435706002,1.9234778359461999,0.995029657393527,0.39184943355934398,0.34758473360807302]
["isoprenaline",8,6,17,1.51871651869416E-2,1.8185232833171301,1.5454408008517999,0.89726299970338497,0.30435054443970699,0.38043042072185101]
["digoxin",1,1,1,0.10580000000000001,0.97551433230083295,0.80941592308412302,0.58641420982642201,0.28324417524922302,0.38849483364243698]
["dextromethorphan",21,12,52,2.5659163893833898E-3,2.5907574992553299,2.2949561095837301,1.13915581201622,0.25966719087185203,0.397560251295345]
["trazodone",7,6,14,1.6957377127699E-2,1.7706413211274801,1.5454408008517999,0.89726299970338497,0.25098607693634001,0.40091243685997802]
["insulin detemir",1,1,8,0.116599999999999,0.93330144957700401,0.80941592308412302,0.58641420982642201,0.21125942110023499,0.41634242277969902]
["insulin aspart",1,1,8,0.116599999999999,0.93330144957700401,0.80941592308412302,0.58641420982642201,0.21125942110023499,0.41634242277969902]
["prochlorperazine",1,1,5,0.14459999999999901,0.83983170704148802,0.80941592308412302,0.58641420982642201,5.1867406088894001E-2,0.47931717273809399]
["oxycodone",5,2,12,0.101998483280084,0.99140628615952797,0.97786358739417201,0.65537118444544296,2.0664165722841701E-2,0.49175677726143602]
["codeine",3,2,12,0.101998483280084,0.99140628615952797,0.97786358739417201,0.65537118444544296,2.0664165722841701E-2,0.49175677726143602]
["diphenoxylate",2,2,12,0.101998483280084,0.99140628615952797,0.97786358739417201,0.65537118444544296,2.0664165722841701E-2,0.49175677726143602]
["imipramine",23,16,43,3.12461295057258E-3,2.5052037715490498,2.7976595055933302,1.2601457624749299,-0.232080877270817,0.59176240142181002]
["hydralazine",2,1,2,0.22489999999999999,0.64801054456436702,0.80941592308412302,0.58641420982642201,-0.27524124725342303,0.60843455022973003]
["erythromycin",3,2,6,0.16603991666539999,0.77978749326367902,0.97786358739417201,0.65537118444544296,-0.302234975890951,0.61876352835466197]
["anakinra",1,1,2,0.2364,0.62635252779078199,0.80941592308412302,0.58641420982642201,-0.31217421444737298,0.62254593626894505]
["metoclopramide",4,3,13,0.123118257468085,0.90967753984121702,1.1427850331257099,0.74354699752386699,-0.31350740983527298,0.62305240399398598]
["isosorbide dinitrate",1,1,3,0.2379,0.62360555796273298,0.80941592308412302,0.58641420982642201,-0.31685856517083399,0.62432453830557399]
["lansoprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412302,0.58641420982642201,-0.33408959972638802,0.63084402607310996]
["rabeprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412302,0.58641420982642201,-0.33408959972638802,0.63084402607310996]
["omeprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412302,0.58641420982642201,-0.33408959972638802,0.63084402607310996]
["pantoprazole",1,1,1,0.24349999999999999,0.61350103444934601,0.80941592308412302,0.58641420982642201,-0.33408959972638802,0.63084402607310996]
["reboxetine",1,1,3,0.27489999999999998,0.560825260156531,0.80941592308412302,0.58641420982642201,-0.423916506049834,0.66418664702904895]
["insulin lispro",2,2,14,0.207915823946524,0.68211245635811302,0.97786358739417201,0.65537118444544296,-0.45127271087805798,0.67410349480501397]
["desipramine",21,16,44,6.0207187095779697E-3,2.2203516627333602,2.7976595055933302,1.2601457624749299,-0.45812782937597801,0.67656969687792601]
["nortriptyline",25,16,42,6.8979879577944396E-3,2.1612775681402701,2.7976595055933302,1.2601457624749299,-0.50500660828570398,0.69322290271742004]
["lurasidone",6,3,9,0.176316142631851,0.75370792403081899,1.1427850331257099,0.74354699752386699,-0.523271710316349,0.69960740764388796]
["atropine",5,3,7,0.18078227174196501,0.742844160487523,1.1427850331257099,0.74354699752386699,-0.537882439133053,0.70467089359500501]
["doxepin",23,15,41,1.08559834489009E-2,1.96433082747584,2.63109387719452,1.22265967885486,-0.54533821737145804,0.70723953799889405]
["prasugrel",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412302,0.58641420982642201,-0.59127352370735398,0.72283141674535001]
["epoprostenol",3,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412302,0.58641420982642201,-0.59127352370735398,0.72283141674535001]
["clopidogrel",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412302,0.58641420982642201,-0.59127352370735398,0.72283141674535001]
["ticlopidine",1,1,4,0.34460000000000002,0.46268472688799001,0.80941592308412302,0.58641420982642201,-0.59127352370735398,0.72283141674535001]
["bupropion",3,3,11,0.20699704398961999,0.68403585641826403,1.1427850331257099,0.74354699752386699,-0.61697401540879604,0.73137406747366995]
["propranolol",5,5,13,0.136752838486048,0.86406365054455703,1.4233947391639401,0.86030645440318698,-0.65015330962199003,0.74220340149729203]
["ondansetron",5,4,20,0.17927192393890301,0.74648772066181202,1.27372904713086,0.79800268107877703,-0.66070119683846296,0.74559802194179803]
["oxybutynin",3,2,5,0.28549784398245498,0.54439716710309904,0.97786358739417201,0.65537118444544296,-0.66140597966305004,0.74582400391624304]
["procyclidine",4,2,5,0.28549784398245498,0.54439716710309904,0.97786358739417201,0.65537118444544296,-0.66140597966305004,0.74582400391624304]
["pheniramine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["fexofenadine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["cetirizine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["meclizine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["diphenhydramine",2,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["hydroxyzine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["loratadine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["triprolidine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["clemastine",1,1,2,0.38059999999999999,0.41953121604899801,0.80941592308412302,0.58641420982642201,-0.66486231148888697,0.746930718288909]
["sapropterin",4,2,4,0.29129857612527998,0.53566163820942403,0.97786358739417201,0.65537118444544296,-0.67473511146042497,0.750077963609451]
["amitriptyline",35,25,71,1.80824346314825E-3,2.7427430962149502,3.7711021469052901,1.4671566857147,-0.70091971818905396,0.75832344093297099]
["dexamethasone",4,2,7,0.31371920928448099,0.50345888828077601,0.97786358739417201,0.65537118444544296,-0.72387176972820899,0.76542776862766404]
["buspirone",2,2,6,0.322016350815584,0.4921220758548,0.97786358739417201,0.65537118444544296,-0.74117007745830599,0.77070483807572598]
["maraviroc",1,1,5,0.42670000000000002,0.36987735714068698,0.80941592308412302,0.58641420982642201,-0.74953600812902799,0.77323289799298101]
["rizatriptan",3,1,3,0.42699999999999999,0.36957212497497499,0.80941592308412302,0.58641420982642201,-0.75005651421601705,0.773389665808348]
["brompheniramine",6,4,9,0.21292785452698801,0.671767521858608,1.27372904713086,0.79800268107877703,-0.75433521659162095,0.77467601948145604]
["galantamine",18,13,36,3.0102242198898101E-2,1.52140115429514,2.3986186986932601,1.1266707935907001,-0.77859260166176902,0.78189013070731295]
["doxylamine",2,2,4,0.36260852651804698,0.44056198795093299,0.97786358739417201,0.65537118444544296,-0.81984318535134804,0.79384724566403198]
["hydrocortisone",2,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["triamcinolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["methylprednisolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["prednisolone",1,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["prednisone",2,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["betamethasone",1,1,2,0.4768,0.32166375326781899,0.80941592308412302,0.58641420982642201,-0.83175366770303305,0.79722599948149298]
["cyproheptadine",6,5,12,0.25352373403627199,0.595981377243891,1.4233947391639401,0.86030645440318698,-0.96176584249161801,0.83191638014043701]
["tranexamic acid",1,1,4,0.56840000000000002,0.24534593074456701,0.80941592308412302,0.58641420982642201,-0.96189686894953996,0.83194929423459896]
["isoniazid",7,3,12,0.50155242223756502,0.29968366783064998,1.1427850331257099,0.74354699752386699,-1.1338911569850101,0.87157989653648804]
["venlafaxine",3,3,6,0.55041381079912399,0.25931067746404102,1.1427850331257099,0.74354699752386699,-1.1881889895377,0.88262051971539901]
["duloxetine",3,3,6,0.55041381079912399,0.25931067746404102,1.1427850331257099,0.74354699752386699,-1.1881889895377,0.88262051971539901]
["sumatriptan",4,2,4,0.64251101829243196,0.19211942030394599,0.97786358739417201,0.65537118444544296,-1.1989299892016101,0.88472241518827699]
["eletriptan",7,2,4,0.64251101829243196,0.19211942030394599,0.97786358739417201,0.65537118444544296,-1.1989299892016101,0.88472241518827699]
["tirofiban",2,2,3,0.85430192553261297,6.8388614768670697E-2,0.97786358739417201,0.65537118444544296,-1.38772499342502,0.91738959882802695]
["chlormethiazole",1,0,0,"N/A"]
["evolocumab",1,0,0,"N/A"]
["chloral hydrate",1,0,0,"N/A"]
["dimethyl fumarate",1,0,0,"N/A"]
["ranitidine",1,0,0,"N/A"]
["pholcodine",1,0,0,"N/A"]
["alosetron",1,0,0,"N/A"]
["metformin",1,0,0,"N/A"]
["aprepitant",1,0,0,"N/A"]
["granisetron",1,0,0,"N/A"]
["meperidine",1,0,0,"N/A"]
["nicotinyl alcohol",1,0,0,"N/A"]
["opium",1,0,0,"N/A"]
["chlorpheniramine",1,0,0,"N/A"]
["cimetidine",1,0,0,"N/A"]
["famotidine",1,0,0,"N/A"]
["nizatidine",1,0,0,"N/A"]
["cortisone",1,0,0,"N/A"]
["zafirlukast",1,0,0,"N/A"]
["dolasetron",1,0,0,"N/A"]
["calcium carbimide",1,0,0,"N/A"]
["benzhexol",1,0,0,"N/A"]
["beclomethasone",1,0,0,"N/A"]
["montelukast",2,0,0,"N/A"]
["corticotrophin",1,0,0,"N/A"]
["palonosetron",1,0,0,"N/A"]
["pizotifen",1,0,0,"N/A"]
["alglucosidase alfa",1,0,0,"N/A"]
["iron polymaltose",1,0,0,"N/A"]
["mepolizumab",1,0,0,"N/A"]
["dihydrocodeine",1,0,0,"N/A"]