GO_ID GO_term GO_category Annotated Significant SymbolList Expected classic_fisher FDR GO:0006997 nucleus organization biological_process 142 47 AAAS,AGFG1,AHCTF1,ANKLE2,ASUN,ATXN7,CCNB2,CHMP3,CHMP5,CHMP6,CTDNEP1,DCTN1,DMPK,FAM118B,LPIN1,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PAFAH1B1,PITPNB,PPP2R1A,PPP2R2A,PSME4,RAE1,RANBP2,RPS19,RTN4,SEH1L,SRPK2,SUMO1,SYCP3,SYNE1,TBPL1,TOR1AIP1,TOR1AIP2,UBXN2B,USPL1,VPS4A 27.88 0.00010 0.00392928870292887 GO:0006406 mRNA export from nucleus biological_process 104 37 AAAS,AGFG1,CHTOP,DDX39B,EIF4E,ENY2,FIP1L1,HNRNPA2B1,NCBP2,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,POLDIP3,RAE1,RANBP2,RBMX2,RNPS1,SEH1L,SHFM1,SMG1,SMG6,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7 20.42 0.00010 0.00392928870292887 GO:0071427 mRNA-containing ribonucleoprotein comple... biological_process 104 37 AAAS,AGFG1,CHTOP,DDX39B,EIF4E,ENY2,FIP1L1,HNRNPA2B1,NCBP2,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,POLDIP3,RAE1,RANBP2,RBMX2,RNPS1,SEH1L,SHFM1,SMG1,SMG6,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7 20.42 0.00010 0.00392928870292887 GO:0034470 ncRNA processing biological_process 403 110 ADAT2,AGO1,AGO2,BMS1,C14orf166,C1D,CCDC59,CDKAL1,CHD7,CPSF3L,DCAF13,DDX1,DDX47,DDX56,DICER1,DIMT1,DROSHA,EIF6,ELAC2,ERI2,EXOSC8,FAM98B,FBL,GTF2H5,HEATR1,HNRNPA2B1,INTS10,INTS12,INTS6,INTS8,KRR1,LSM6,LTV1,METTL1,METTL15,METTL16,MPHOSPH10,MRPL1,MRPS11,MTO1,NAT10,NGDN,NOL8,NOP10,NOP2,NOP56,NOP58,NSA2,NSUN4,PDCL3,QTRT1,RCL1,RIOK3,RPF1,RPF2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RPUSD1,RPUSD4,RRNAD1,RRP1,RRP36,RRP8,SMAD2,SNU13,SSB,TARBP1,TARBP2,TFB1M,THUMPD1,THUMPD3,TPRKB,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,TRUB1,TSEN15,TSEN2,TYW5,UBA5,UBA52,UTP11,UTP14A,UTP4,WDR12,WDR43,WDR75,ZBTB8OS,ZCCHC11 79.12 0.00010 0.00392928870292887 GO:1901796 regulation of signal transduction by p53... biological_process 150 49 AKT1,ATR,AURKA,AURKB,BANP,BRCA1,BRD7,BRIP1,CD44,CD74,CDK5RAP3,CHD3,CSNK2A1,CSNK2A2,DNA2,DYRK2,EHMT1,EHMT2,HDAC1,HDAC2,HUS1,KAT6A,L3MBTL1,MAPKAPK5,MBD3,MDM2,MDM4,MEAF6,PHF20,PIN1,PLK3,PRMT5,PTTG1IP,RAD17,RBBP4,RBBP7,RBBP8,RFC2,RFC4,RMI1,RPA3,SENP2,SMYD2,TAF2,TOPBP1,TP63,UBA52,WRN,ZNF385A 29.45 0.00010 0.00392928870292887 GO:0000070 mitotic sister chromatid segregation biological_process 123 42 ANAPC10,ANAPC4,ANKRD53,BUB1B,CDC23,CDC27,CDC6,CENPA,CEP57,CEP57L1,CHMP3,CHMP5,CHMP6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,H2AFY,INO80,LCMT1,MAU2,NCAPG,NIPBL,NSMCE2,NUSAP1,PDS5B,PPP2R1A,PSMG2,SEH1L,SLF1,SMC1A,SMC2,SMC4,SPAG5,SPDL1,TEX14,TTK,VPS4A,WAPL,XRCC3,ZNF207 24.15 0.00011 0.00423364754098361 GO:0016458 gene silencing biological_process 210 64 AAAS,AGO1,AGO2,BAHCC1,BAZ2A,CNOT2,CNOT7,CNOT8,DICER1,DOT1L,DROSHA,EIF6,EXD1,FKBP6,FXR1,H2AFV,H2AFY,HAT1,HDAC1,HDAC2,HELLS,HIST2H2AC,HNRNPA2B1,IPO8,KMT2D,LIMD1,MBD3,MIER1,MORF4L1,NCBP2,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PABPC1,PIWIL4,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PUM2,RAE1,RANBP2,RBM4,RRP8,SEH1L,SIRT2,SIRT5,SMAD2,SMARCA5,SOX6,TARBP2,TGFB1,TNRC18,UBE2B,ZCCHC11 41.23 0.00011 0.00423364754098361 GO:0006409 tRNA export from nucleus biological_process 32 16 AAAS,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,XPOT 6.28 0.00011 0.00423364754098361 GO:0071431 tRNA-containing ribonucleoprotein comple... biological_process 32 16 AAAS,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,XPOT 6.28 0.00011 0.00423364754098361 GO:0018193 peptidyl-amino acid modification biological_process 1172 280 AAAS,ABI1,ABI3,ACE,ACTL6A,ADNP,ADORA1,AGBL1,AGTPBP1,AKT1,APBB1,ARHGEF2,ARID4A,ARL2BP,ASH1L,ATAT1,ATF2,ATP2B4,ATR,ATRX,AURKA,AURKB,BAG4,BAX,BAZ1A,BCL2,BLK,BRAF,BRCA1,BRD7,BTK,CALM1,CAMK2A,CD44,CD74,CD81,CDC42,CFAP20,CLK2,CNTN1,CSF1R,CSNK1G1,CTBP1,CTR9,CUX1,DAD1,DDOST,DDR1,DDR2,DMPK,DNAJC24,DOCK7,DOT1L,DPH1,DPH2,DPH3,DPH5,DPY19L1,DPY19L3,DPY19L4,DR1,DYRK2,DYRK4,EGF,EGFLAM,EGFR,EHMT1,EHMT2,EIF2AK2,ELP4,ENPP2,EPHA10,EPHA4,EPHB2,EZH2,FAM150A,FAM76B,FBXO11,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FKBP3,FKBP4,FKBP6,FKBP8,FUT8,GALNT11,GALNT2,GGCX,GOLGA7,GPRC5B,GSK3B,H2AFY,HAT1,HDAC1,HDAC2,HDAC6,HDAC7,HDAC9,HIPK3,HMGA2,HNRNPC,HNRNPK,HSPH1,IGF1R,IL15,IL1B,IL22RA2,INCENP,JADE1,JMJD6,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KDM6A,KMT2A,KMT2D,KMT2E,LIF,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP4K1,MAP6D1,MAPK8,MAPKAPK5,MASTL,MBD3,MCFD2,MDM2,MEAF6,MED24,MELK,METAP2,METTL21A,MKNK1,MORF4L1,MST1R,MTA1,MTF2,MTOR,MVP,MYB,NAA10,NAA16,NAA20,NAA25,NAA60,NCK1,NCOA1,NCOA2,NDC1,NDUFAF7,NKTR,NMT1,NOP58,NSMCE1,NSMCE2,NSMCE4A,NTRK2,NTRK3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OGFOD1,OGT,OSTC,P4HA1,PAK1,PAK2,PAQR3,PDCD10,PDCL3,PDE4D,PDGFRB,PDK3,PEAK1,PFN2,PHC3,PHF1,PHF20,PIAS1,PIK3CA,PIN1,PKDCC,POR,PPIE,PPIL2,PPP2R1A,PPWD1,PRDM16,PRKCZ,PRLR,PRMT1,PRMT3,PRMT5,PTK2,PTK2B,PTPN2,PTPN6,PWP1,RAD52,RAE1,RANBP2,RELN,RNF2,RNF212,RNF4,ROS1,RPN2,SAE1,SEH1L,SEMA4D,SENP2,SENP6,SGK1,SIRT2,SIRT5,SMAD4,SMC1A,SMC6,SMG1,SMYD2,SMYD3,SP3,SPOCK3,SPTBN4,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,STAP2,STK32B,SUMO1,SUMO2,TBK1,TGFA,TGFB1,TGFBR1,TLK2,TMX3,TNK2,TNKS,TOP2B,TPGS1,TPST2,TTC9,TTC9C,TTK,TTLL4,TYK2,UBA2,UBE2G2,UGGT2,USPL1,VEGFA,WDR75,WEE1,WHSC1,WHSC1L1,WRN,YEATS4,ZAP70,ZMYM2,ZNF451 230.11 0.00011 0.00423364754098361 GO:2000112 regulation of cellular macromolecule bio... biological_process 3858 838 ABCA2,ABLIM3,ACAD8,ACOD1,ACOT8,ACTL6A,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCL2,BCLAF1,BLZF1,BMPR1B,BOLL,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C12orf65,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CAPRIN1,CARF,CASK,CBX5,CCDC59,CCDC88A,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CD81,CDC123,CDC42,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB1,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTC1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK1,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DDX6,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNA2,DNAJC1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,EPRS,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FXR1,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GIGYF2,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRB7,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HHATL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,HUS1,ICE1,ICE2,IGF1R,IGF2BP3,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA2,ITGA6,ITGB1BP1,ITGB3BP,ITM2C,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIG3,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALSU1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K2,MAPK8,MAPKAPK5,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,METTL14,MGA,MIER1,MKNK1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTG1,MTIF2,MTOR,MTRF1,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NAT10,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NEK7,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NGDN,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NOX4,NPAS3,NPM2,NR2C1,NR3C1,NR3C2,NSUN4,NTRK3,NUCKS1,NUP107,NUP35,NVL,OGFOD1,OGT,ONECUT2,OTULIN,PABPC1,PAIP2,PAK3,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PDGFRB,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PIWIL4,PKNOX2,PLA2G10,PLCB1,PLK3,PNKP,PNRC2,POFUT1,POLA1,POLDIP3 757.48 0.00012 0.0045809756097561 GO:0051338 regulation of transferase activity biological_process 919 225 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AMBRA1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ATP2B4,AURKB,BAX,BCCIP,BIRC7,BRAF,BUB1B,CACUL1,CALM1,CCDC88A,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC23,CDC27,CDC42,CDC6,CDK12,CDK5RAP3,CDK7,CDKN3,CHAD,CHORDC1,CHRNA3,CHRNA7,CSF1R,CTC1,CUL1,DAB2IP,DCUN1D4,DDR2,DNAJA1,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF2AK2,EIF4A2,ELP4,EPHA4,EZH2,FAF1,FAM150A,FAM58A,FBXO7,FGFR1,FGFR1OP,FRS2,FZR1,GADD45G,GBAS,GEN1,GMFB,GMFG,GPRC5B,GRHL2,GSK3B,GSTP1,H2AFY,HACD3,HERC5,HGS,HIPK3,HMGN1,HSPH1,HTR2B,IGF1R,IL1B,IRAK1,ITGB1BP1,KAT2B,KRAS,LAMTOR3,LAT,LCMT1,LIMK1,LRP6,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MIDN,MNAT1,MST1R,MTOR,MVP,NCK1,NEK10,NEK7,NF1,NLRC5,NOX4,NTRK3,NVL,OSBPL8,PAK1,PAK2,PAK3,PAQR3,PDCD10,PDE5A,PDGFRB,PFKFB1,PIK3CA,PIK3CB,PIK3R2,PIK3R3,PIK3R5,PIN1,PNKP,PODN,POT1,PPP1R1B,PPP1R3F,PPP2R1A,PPP2R3C,PRKAR2A,PRKCZ,PRLR,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RANBP2,RAP1A,RAPGEF2,RBL1,RELN,RFC2,RFC4,RGN,RGS14,RGS3,RPS2,RTN4RL2,SASH1,SHC2,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPRY1,TAB2,TAB3,TARBP2,TCP1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TLR9,TNFRSF10B,TNKS,TOM1L1,TRAF4,TTK,UBA52,UBE2E1,UVRAG,VEGFA,WNT11,WWTR1,XRCC3,ZNF207,ZP4 180.44 0.00012 0.0045809756097561 GO:0033043 regulation of organelle organization biological_process 975 237 ACTR2,ACTR3C,ADPRHL1,AKT1,ALOX15,AMBRA1,ANAPC10,ANAPC4,ANKRD53,ANLN,ANXA2,ARF1,ARHGAP6,ARHGEF15,ARHGEF2,ARPC1A,ARPC1B,ATAT1,ATR,ATRX,ATXN2,AURKA,AURKB,BAG4,BAX,BBC3,BCAS3,BCL2,BLK,BOK,BORA,BRAF,BRCA1,BRD7,BUB1B,C16orf45,C1QBP,C2CD5,CALCOCO2,CAMSAP3,CAPZA1,CARMIL2,CASP8,CCDC88A,CCT3,CCT7,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDK13,CELSR1,CENPJ,CHMP3,CHMP5,CHORDC1,CHTOP,CLASP1,CLASP2,CLIP1,CLTC,CNOT2,CSF1R,CSNK2A1,CSNK2A2,CTBP1,CTR9,CUL3,CUL9,CXCL12,CYFIP1,CYLD,DAPK3,DCTN1,DNM1L,DYNC1LI1,ECT2,EGF,EML2,EVL,FCHSD1,FES,FHOD3,FKBP4,FMN1,FZR1,GEN1,GMFB,GMFG,GSK3B,GSN,H2AFY,HDAC6,HDAC8,HNRNPC,HNRNPU,HORMAD1,IL1B,ITGB1BP1,JAM3,KANK1,KMT2A,KNTC1,L3MBTL1,LCMT1,LCP1,LIF,LIG3,LIG4,LIMK1,LRPPRC,MALSU1,MAP1S,MAP2K7,MAP6D1,MAP9,MAPK8,MAPKAPK5,MARCH5,MDM1,MEF2C,MFF,MID1IP1,MIER1,MKI67,MSX2,MTBP,MTF2,MTG1,MTOR,MYB,MYOC,NAT10,NCK1,NEB,NEK7,NIPBL,NME6,NMT1,NOX4,NPM2,NPRL3,NSMCE2,NSUN4,NTRK3,NUSAP1,OGT,OMA1,OPA1,PAFAH1B1,PAK1,PAK3,PAN3,PARP10,PAX7,PAXBP1,PDCD5,PDGFRB,PFDN2,PFN2,PHF1,PHIP,PHLDB1,PICK1,PIN1,PLCB1,PLK4,PLXNB1,PNKP,POT1,PRMT5,PSMG2,PTK2,PTK2B,RAB3GAP2,RAB5A,RABGAP1L,RACGAP1,RALB,RNF4,RUNDC1,SEC24B,SENP6,SFPQ,SGSM1,SGSM3,SIRT2,SLAIN2,SLF1,SMAD4,SMG6,SORBS3,SPAG5,SPTB,SPTBN1,SPTBN4,STMN4,SYNPO,SYNPO2,SYT1,TAPT1,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TCP1,TEX14,TGFA,TGFB1,TGFBR1,TIGAR,TLK2,TMEFF2,TMEM67,TNKS,TOM1L1,TP63,TRAPPC12,TRIOBP,TRIP12,TTK,TWF1,UBE2B,USP6NL,VEGFA,VIL1,VPS11,WAPL,WNT11,XPO1,XRCC3,YWHAQ,YWHAZ,ZNF207,ZNF451 191.43 0.00013 0.00490293172690763 GO:0051347 positive regulation of transferase activ... biological_process 603 155 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AMBRA1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ATP2B4,AURKB,BAX,BIRC7,BRAF,BUB1B,CACUL1,CALM1,CCDC88A,CCNC,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC23,CDC27,CDC42,CDC6,CHRNA3,CHRNA7,CSF1R,CUL1,DAB2IP,DCUN1D4,DDR2,DUSP9,ECT2,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM150A,FAM58A,FGFR1,FRS2,FZR1,GADD45G,GPRC5B,GRHL2,HACD3,HMGN1,HSPH1,HTR2B,IGF1R,IL1B,IRAK1,ITGB1BP1,KRAS,LAMTOR3,LAT,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NEK7,NOX4,NTRK3,NVL,OSBPL8,PAK1,PAK2,PAK3,PDCD10,PDE5A,PDGFRB,PFKFB1,PIK3CA,PIK3CB,PIK3R5,PIN1,PNKP,POT1,PPP2R3C,PRKAR2A,PRKCZ,PRLR,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTK2,PTK2B,RALB,RAP1A,RAPGEF2,RELN,RFC2,RFC4,RPS2,SASH1,SHC2,SNX9,SPAG9,SPDYA,TAB2,TAB3,TCP1,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TNKS,TOM1L1,TRAF4,UBA52,UBE2E1,VEGFA,WNT11,ZP4 118.39 0.00013 0.00490293172690763 GO:0006325 chromatin organization biological_process 693 175 ACTL6A,ANP32A,APBB1,ARID1B,ARID2,ARID4A,ASH1L,ATF2,ATRX,ATXN7,AURKA,AURKB,BAHCC1,BANP,BAP1,BAZ1A,BAZ2A,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,CABIN1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CHD1,CHD2,CHD3,CHD6,CHD7,CHRAC1,CHTOP,CTBP1,CTR9,CUL4B,DAPK3,DDB1,DOT1L,DR1,EHMT1,EHMT2,ELP4,EMSY,ENY2,ESR1,EYA3,EYA4,EZH2,GATAD2B,H2AFY,HAT1,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELLS,HIST1H2BN,HLTF,HMGA2,HMGN1,HNRNPC,HSF4,IL1B,INO80,INO80C,ITGB3BP,JADE1,JMJD1C,JMJD6,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KDM1B,KDM5D,KDM6A,KDM7A,KMT2A,KMT2D,KMT2E,L3MBTL1,L3MBTL3,LEO1,LIF,MAP1S,MAP3K12,MAPK8,MBD3,MBTD1,MCM2,MEAF6,MED24,MIER1,MIS18BP1,MORF4L1,MTA1,MTA3,MTF2,MYB,MYSM1,NAA60,NAP1L1,NAP1L4,NASP,NCOA1,NCOA2,NCOR1,NEK11,NIPBL,NPM2,NR3C1,NUCKS1,OGT,PARP10,PAX7,PAXBP1,PHF1,PHF20,PHF21A,PRDM16,PRMT1,PRMT3,PRMT5,PSME4,PWP1,RBBP4,RBBP7,RBL1,RNF2,RNF8,RRP8,SAP18,SART3,SFPQ,SIRT2,SIRT6,SMAD4,SMARCA2,SMARCA5,SMARCAD1,SMARCD1,SMARCD2,SMARCE1,SMYD2,SMYD3,SUPT4H1,SYCP3,TBL1XR1,TGFB1,TLK2,TNRC18,TP63,TRIP12,TTF1,UBE2B,UBE2E1,USP15,USP3,USP34,VEGFA,WAC,WDR75,WHSC1,WHSC1L1,YEATS4,ZNF451 136.06 0.00013 0.00490293172690763 GO:0044281 small molecule metabolic process biological_process 3418 747 ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABHD3,ABR,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACIN1,ACOT8,ACOX3,ACOXL,ACSBG1,ACSF3,ACSL1,ACSM6,ADA,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADIPOR1,ADIPOR2,ADK,ADNP,ADPGK,ADPRHL1,AGFG1,AHSA2,AIPL1,AK2,AK6,AKAP12,AKR1A1,AKR1B1,AKT1,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALOX15,AMD1,AMDHD2,AMPD3,AMPH,AMT,ANGPTL3,APLP1,APOBEC3F,APRT,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ARPP19,ASNS,ASPG,ATAD1,ATF4,ATF7IP,ATIC,ATL2,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATRX,AZIN2,BAG4,BCAS3,BCHE,BCKDHB,BCKDK,BMS1,BNIP2,BPNT1,BPTF,BRCA1,BRIP1,CA1,CA12,CACNA1A,CACNA1H,CALM1,CAMK2A,CAMK2G,CARS,CASK,CCL25,CCZ1,CD74,CDC42,CDC42EP3,CDK7,CECR1,CES1,CHAC2,CHD1,CHD2,CHD3,CHD6,CHN1,CHST1,CHTOP,CKMT2,CLK2,CLN3,CLN8,CLU,CMPK1,CNDP2,COASY,COQ4,COX5A,COX6A1,COX7A2L,CPQ,CPS1,CPT1C,CPT2,CRBN,CREM,CROT,CRYM,CS,CTRB1,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP4F12,CYP4F8,CYTH4,DAB2IP,DALRD3,DARS,DARS2,DBI,DBT,DCTD,DCXR,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEGS1,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHCR7,DHFR,DHX15,DHX40,DHX57,DLAT,DLD,DLG2,DLG3,DMC1,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH9,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DNM3,DOCK4,DOCK7,DPAGT1,DPYS,DQX1,DTYMK,DUOXA1,DYRK2,ECT2,EGF,EGFLAM,EGFR,EIF2S3,EIF4A1,EIF4A2,EIF5B,EIF6,ELMOD3,ELOVL6,ELOVL7,ENO4,ENOPH1,ENOSF1,ENPP2,ENTPD4,ENTPD8,EPHA4,EPRS,EPS8L1,ERCC6L2,ERO1A,ESD,ETFA,EZH2,FABP5,FADS1,FAM13B,FAR1,FARP1,FARP2,FAXDC2,FDXR,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FLAD1,FNBP1,FNBP1L,FRS2,FTCD,FUOM,FUT1,FUT8,FUT9,GABBR1,GARS,GART,GBA2,GBAS,GBP5,GCAT,GCGR,GCLC,GCLM,GCSH,GDA,GDI2,GFRA2,GGCT,GGH,GGPS1,GGT1,GIF,GIPR,GLRX2,GLS,GLS2,GMIP,GMPS,GNA12,GNA14,GNGT1,GNL2,GNPAT,GNPDA2,GPC1,GPSM1,GRM7,GRM8,GSK3B,GSTA5,GSTM5,GSTP1,GTF2H2,GTF2H3,GTPBP10,GUK1,HACD1,HACD3,HARS,HDC,HDLBP,HELB,HEXB,HLTF,HMGCS1,HNRNPU,HPRT1,HS6ST2,HS6ST3,HSD17B3,HSD17B4,HSD17B7,HSPA8,HSPD1,HSPH1,HTR2B,HYAL1,IDO1,IL1B,IL2RA,IMPDH1,INO80,INPP1,INPP5A,INPP5B,IP6K2,ITGA6,ITGB1BP1,ITSN2,KALRN,KAT2B,KCNAB2,KDSR,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LBR,LCMT1,LDLRAP1,LLGL2,LONRF1,LPCAT3,LPCAT4,LPIN1,LRAT,LSS,LTA4H,LTF,LYPLA1,MACROD2,MADD,MAN2A1,MAN2C1,MAT2A,MBTPS2,MCF2,MCF2L,MDH1,METTL21A,MFN1,MID1IP1,MIDN,MMAA,MME,MNAT1,MSMO1,MSRA,MSTO1,MT-ATP6,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD1,MTHFD2L,MTIF2,MTMR7,MT-ND4,MT-ND4L,MTO1,MTOR,MTRR,MUTYH,MYH10,MYH9,MYO10,MYO18A,MYO1B,NADK,NADSYN1,NAGK,NARS,NCK1,NCOA2,NCOR1,NCOR2,NDUFA3,NDUFA7,NDUFA9,NDUFAF7,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NF1,NISCH,NIT2,NKX1-1,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NNT,NOS3,NOX1,NOX4,NPRL3,NSDHL,NT5C2,NT5C3B,NTRK2,NUDT9,OARD1,OAZ1,OAZ2,OCRL,OGT,OMA1,OPA1,OPRM1,OSBPL1A,OSBPL5,P2RY12,P4HA1,PAFAH1B1,PANK1,PANK3,PANK4,PCBD1,PCK2,PCYOX1,PCYT1A,PDCL3,PDE1B,PDE2A,PDE4D,PDE5A,PDE6B,PDE6D,PDE8A,PDE9A,PDGFRB,PDHB,PDK3,PDSS1,PDXK,PDZD3,PFKFB1,PFN2,PGM3,PHYKPL 671.09 0.00015 0.0056346 GO:0002474 antigen processing and presentation of p... biological_process 91 33 ABCB1,ABCB4,ACE,CYBB,ERAP2,FCGR1B,ITGAV,LNPEP,MR1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SEC24A,SEC24B,SEC24D,SEC31A 17.87 0.00016 0.0059155905511811 GO:0061136 regulation of proteasomal protein catabo... biological_process 176 55 AKT1,ANAPC10,ANAPC4,ANKIB1,ARIH1,AURKA,BUB1B,CDC23,CDC6,CHFR,CLU,CSNK2A1,CSNK2A2,CUL3,DAB2IP,DYNC1LI1,FBXO22,GCLC,GEN1,GNA12,GSK3B,KLHL40,LCMT1,MDM2,N4BP1,NSMCE2,NUB1,PBK,PIAS1,PLK3,PRICKLE1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSME3,PSMG2,RCHY1,RNF138,RNF14,RNF166,SDCBP,SIRT2,SUMO1,SUMO2,TEX14,TLK2,TTK,UCHL5,UFL1,WAC,WNT10B,XRCC3,ZNF207 34.56 0.00016 0.0059155905511811 GO:0009896 positive regulation of catabolic process biological_process 351 97 AGO2,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANKIB1,ARIH1,ATG4B,AURKA,BUB1B,CALCOCO2,CDC23,CDC27,CDK5RAP3,CHFR,CLU,CNOT7,CNOT8,CPEB3,CSNK2A1,CSNK2A3,CUL1,CUL3,CUL4B,DAB2IP,EGF,FBXO22,FZR1,GCLC,GGA1,GPC3,GSK3B,IL1B,MDM2,MTDH,NEDD4L,NKD1,NRDC,NSMCE2,NUB1,OAZ1,OAZ2,PABPC1,PIAS1,PIK3CB,PLK3,PNPT1,POLR2G,PRICKLE1,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,RAB3GAP2,RALB,RCHY1,RNF138,RNF14,RNF166,SCOC,SIRT2,SNX9,SORL1,STX5,SUMO1,SUMO2,TBC1D5,TFEB,TIPARP,TNFSF12,UBA52,UBE2E1,UVRAG,WAC,ZC3H12A 68.92 0.00016 0.0059155905511811 GO:0009987 cellular process biological_process 15447 3076 AAAS,AAK1,AATK,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABHD3,ABI1,ABI3,ABLIM2,ABLIM3,ABR,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAD2,ADAM10,ADAM22,ADAM23,ADAMDEC1,ADAMTSL1,ADAT2,ADCY10,ADCY4,ADCYAP1,ADD3,ADGRA3,ADGRD1,ADGRG2,ADGRG7,ADIPOR1,ADIPOR2,ADK,ADNP,ADORA1,ADPGK,ADPRHL1,AEBP1,AFF3,AGBL1,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AHSA2,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP2,AKAP3,AKAP7,AKIP1,AKNA,AKR1A1,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG9,ALKBH2,ALOX15,ALPK1,ALPL,ALPP,AMBRA1,AMD1,AMDHD2,AMER1,AMER3,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKH,ANKIB1,ANKLE2,ANKRD10,ANKRD49,ANKRD53,ANKRD6,ANLN,ANO10,ANO2,ANO6,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APLP1,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQP7,AQP8,AQR,ARAP2,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL5C,ARL6,ARL8A,ARMC4,ARPC1A,ARPC1B,ARPP19,ARPP21,ARSA,ART3,ASAH1,ASB15,ASH1L,ASIC2,ASNS,ASPG,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATG3,ATG4B,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN10,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZI2,AZIN2,B3GALNT2,BAG4,BAHCC1,BAIAP3,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCL7C,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLCAP,BLK,BLNK,BLZF1,BMP2K,BMPR1B,BMS1,BNIP2,BOC,BOK,BOLL,BORA,BPIFB1,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD2,BTBD9,BTF3,BTG3,BTK,BUB1B,BUD31,C11orf88,C12orf4,C12orf65,C14orf166,C16orf45,C16orf62,C16orf89,C19orf68,C1D,C1QBP,C1QTNF5,C2,C2CD5,C3orf33,C3orf38,C4A,C4B,C5AR2,C6orf120,C9orf142,CA1,CA12,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPRIN1,CAPS,CAPZA1,CARD16,CARF,CARMIL2,CARS,CASK,CASKIN1,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC114,CCDC126,CCDC14,CCDC59,CCDC6,CCDC66,CCDC78,CCDC80,CCDC88A,CCDC88B,CCDC88C,CCL25,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CD14,CD160,CD200,CD22,CD247,CD2BP2,CD3G,CD44,CD46,CD52,CD6,CD7,CD74,CD79B,CD81,CD82,CD9,CDC123,CDC14B,CDC20B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDH23,CDH26,CDH8,CDHR1,CDHR3,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDON,CDS2,CEACAM5,CECR1,CELSR1,CELSR2,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP135,CEP164,CEP192,CEP290,CEP350,CEP57,CEP57L1,CEP63,CEP70,CEP89,CERS2,CES1,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CFLAR,CHAC2,CHAD,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHL1,CHMP3,CHMP5,CHMP6,CHN1,CHODL,CHORDC1,CHRAC1,CHRD,CHRM2,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CKAP4,CKMT2,CLASP1 3032.86 0.00016 0.0059155905511811 GO:0030029 actin filament-based process biological_process 633 161 ABI1,ABLIM2,ABLIM3,ABR,ACTG1,ACTN1,ACTR2,ACTR3C,AKAP2,ALOX15,ANK2,ANTXR1,ARF1,ARHGAP26,ARHGAP6,ARHGEF15,ARHGEF2,ARPC1A,ARPC1B,ATP2C1,ATXN3,BAG4,BCAR1,BCAS3,BCL2,BRAF,CACNA1C,CACNA2D1,CAPZA1,CARMIL2,CATIP,CCDC88A,CDC42,CDC42EP3,CELSR1,CFLAR,CLASP1,CLASP2,COBL,CORO2B,CORO7,CSF1R,CTNNA1,CUL3,CXADR,CXCL12,CYFIP1,DAAM1,DAPK3,DES,EHD2,EPB41L3,EVL,FARP2,FAT1,FCHSD1,FES,FGD3,FGD4,FGD6,FGF12,FHOD3,FLII,FMN1,FMN2,FMNL2,FNBP1L,FOXJ1,FRMD3,FRMD6,FRY,FRYL,GMFB,GMFG,GSN,HSP90B1,ITGB1BP1,JAM3,KANK1,KIF23,KRAS,LCP1,LIMCH1,LIMK1,LLGL2,MEF2A,MEF2C,MINK1,MKLN1,MLPH,MOB2,MTOR,MYBPC1,MYH10,MYH9,MYO18A,MYO1B,MYOC,MYOZ3,NCK1,NEB,NEDD4L,NF1,NISCH,NOX4,NTRK3,NUP155,PAFAH1B1,PAK1,PAK3,PALLD,PARVG,PAWR,PDCD10,PDE4D,PDGFRB,PDLIM3,PDLIM7,PFN2,PICK1,PIP5K1A,PIP5K1C,PKP2,PLEK2,PRKCZ,PTK2B,RAC2,RACGAP1,RAP1GDS1,RHOF,RUFY3,RYR2,SCN3B,SDAD1,SDCBP,SHTN1,SORBS2,SORBS3,SPTB,SPTBN1,SPTBN4,SRI,SUMO1,SYNPO,SYNPO2,TGFB1,TGFBR1,TLN1,TMEFF2,TNNI3,TNNT1,TNNT2,TNXB,TRIOBP,TRIP10,TRPM7,TTC17,TWF1,VIL1,WNT11,ZYX 124.28 0.00017 0.00618786821705426 GO:0043085 positive regulation of catalytic activit... biological_process 1488 346 ABI1,ABR,ACAP1,ACAP2,ACE,ACSL1,ADCY4,ADCYAP1,ADGRD1,ADNP,ADORA1,ADPRHL1,AGFG1,AHSA2,AKT1,AMBRA1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ARL1,ATP1B1,ATP2B4,AURKB,AZIN2,BAX,BCAS3,BCL2,BIRC7,BNIP2,BOK,BRAF,BUB1B,CACUL1,CALM1,CAMK2A,CAMK2G,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCZ1,CD74,CD81,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CFLAR,CHN1,CHRNA3,CHRNA7,CHTOP,COL4A3,CR1,CSF1R,CUL1,CYTH4,DAB2IP,DAPK1,DBF4,DCUN1D4,DDR2,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DUSP9,ECT2,EGF,EGFR,EIF2AK2,ELMOD3,EPHA4,EPS8L1,ESR1,EZH2,FADD,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FAS,FCER2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FNTA,FRS2,FZR1,GADD45G,GCGR,GCLM,GDI2,GFRA2,GIPR,GMFB,GMFG,GMIP,GPIHBP1,GPRC5B,GRHL2,GSK3B,GSN,HACD3,HMGN1,HNRNPU,HSPD1,HSPH1,HTR2B,IGF1R,IL1B,IL2RA,INPP5B,IRAK1,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,KRAS,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MCF2,MCF2L,MEF2C,MID1IP1,MST1R,MTCH1,NCK1,NEK10,NEK7,NF1,NLRP12,NOS3,NOX4,NPM2,NPRL3,NSMAF,NTRK3,NVL,OCRL,OGT,OSBPL8,P2RY12,PAK1,PAK2,PAK3,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PFKFB1,PFN2,PIK3CA,PIK3CB,PIK3R2,PIK3R5,PIN1,PKP4,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,PNKP,POR,POT1,PPP1R12A,PPP1R12B,PPP2R3C,PREB,PRKAR2A,PRKCZ,PRLR,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTK2,PTK2B,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALB,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RELN,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,ROBO1,RP2,RPGR,RPS2,RUNDC1,RYR2,SAE1,SASH1,SBF1,SEMA4D,SFTPB,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPAG9,SPATA13,SPDYA,SPTB,SPTBN1,SPTBN4,SSBP1,ST5,SUMO1,TAB2,TAB3,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TCP1,TELO2,TGFA,TGFB1,TGFBR1,THY1,TLR9,TNFRSF10B,TNKS,TNNT2,TOM1L1,TOR1AIP1,TOR1AIP2,TRADD,TRAF4,TRIO,TRIP10,TSHR,UBA2,UBA52,UBE2E1,USP6NL,VAV1,VEGFA,WNT11,WRN,ZP4 292.15 0.00017 0.00618786821705426 GO:0006417 regulation of translation biological_process 292 83 AGO1,AGO2,AKT1,ATF4,ATXN2,BOLL,C12orf65,C1QBP,CAPRIN1,CDC123,CNOT2,CPEB1,CPEB3,DAPK1,DAPK3,DDX1,DDX39B,DDX6,DNAJC1,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,EPRS,FXR1,GIGYF2,GRB7,HAP1,HNRNPD,IGF2BP3,IMPACT,ITGA2,LRPPRC,MALSU1,MAPKAPK5,METTL14,MKNK1,MTG1,MTIF2,MTOR,MTRF1,NCBP2,NGDN,NSUN4,OGFOD1,PABPC1,PAIP2,PIWIL4,POLDIP3,POLR2G,PTCD3,PTK2B,PUM3,PURA,RBM4,RPS5,RPS6KA1,RPS6KB1,RPS6KB2,RXRA,SERP1,TARBP2,TIA1,TYMS,UNK,YBX3,YRDC,ZC3H12A,ZNF385A,ZNF706 57.33 0.00017 0.00618786821705426 GO:0051302 regulation of cell division biological_process 288 82 AKT1,ANAPC10,ANAPC4,ANLN,AURKA,AURKB,BIRC6,BORA,BUB1B,CALM1,CCNC,CCNL2,CCNT1,CCNT2,CDC23,CDC27,CDC42,CDC6,CDK13,CHMP3,CHMP5,CSNK2A1,CSNK2A2,CSPP1,CUL3,CUL9,DAPK3,DYNC1LI1,E2F7,ECT2,EGF,EGFR,FAM58A,FGF5,FZR1,GEN1,GKN1,H2AFY,HORMAD1,HTR2B,IL1B,ITGB1BP1,KIF23,KNTC1,L3MBTL1,LCMT1,LIF,MAP9,MKI67,MSX2,MTBP,NME6,NPM2,NSMCE2,NUSAP1,PDGFRB,PHIP,PIK3C3,PIN1,PKP4,PLCB1,PLK3,PRMT5,PRPF40A,PSMG2,RACGAP1,SDCCAG3,SIRT2,SLF1,SPDYA,TEX14,TGFA,TGFB1,TOM1L1,TP63,TTK,UBE2B,UVRAG,VEGFA,VPS4A,XRCC3,ZNF207 56.55 0.00017 0.00618786821705426 GO:0032774 RNA biosynthetic process biological_process 3779 819 AAAS,ABCA2,ABLIM2,ABLIM3,ACAD8,ACOD1,ACTL6A,ACTN1,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ARL2BP,ASH1L,ASUN,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CPSF3L,CRCP,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1,CSTF3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DRG1,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,EIF4A2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FIP1L1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FUS,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF2BP,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,INTS10,INTS12,INTS6,INTS8,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LIN9,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NDC1,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUDT21,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OGT,ONECUT2,OTULIN,PABPN1,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLDIP3,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R1B,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRIM1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1 741.97 0.00020 0.00722384615384615 GO:0051340 regulation of ligase activity biological_process 134 44 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CDC23,CDC27,CUL1,DCUN1D4,DYNC1LI1,FZR1,GCLM,GEN1,LCMT1,LIMK1,MID1IP1,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,TEX14,TTK,UBA52,UBE2E1,XRCC3,ZNF207 26.31 0.00020 0.00722384615384615 GO:1901991 negative regulation of mitotic cell cycl... biological_process 150 48 AURKA,BAX,BCL2,BRD7,BUB1B,CDC6,CDK5RAP3,CENPJ,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DNA2,DYNC1LI1,E2F7,EZH2,FANCI,FBXO7,FHL1,FOXN3,GEN1,GIGYF2,HMGA2,HUS1,JADE1,KANK2,LCMT1,MDM2,MDM4,MYO16,NAE1,PCBP4,PLK3,PRMT1,PSMG2,PTEN,RAD17,RFWD3,SLF1,TEX14,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 29.45 0.00021 0.00755597701149425 GO:0034248 regulation of cellular amide metabolic p... biological_process 311 87 AGO1,AGO2,AKT1,ATF4,ATXN2,BOLL,C12orf65,C1QBP,CAPRIN1,CDC123,CNOT2,CPEB1,CPEB3,DAPK1,DAPK3,DDX1,DDX39B,DDX6,DNAJC1,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,EPRS,FXR1,GIGYF2,GRB7,HAP1,HNRNPD,IGF2BP3,IMPACT,ITGA2,LRPPRC,MALSU1,MAPKAPK5,METTL14,MKNK1,MTG1,MTIF2,MTOR,MTRF1,NCBP2,NGDN,NSMAF,NSUN4,OGFOD1,ORMDL2,ORMDL3,PABPC1,PAIP2,PIWIL4,POLDIP3,POLR2G,PTCD3,PTK2B,PUM3,PURA,RBM4,RPS5,RPS6KA1,RPS6KB1,RPS6KB2,RXRA,SERP1,TARBP2,TIA1,TIGAR,TYMS,UNK,YBX3,YRDC,ZC3H12A,ZNF385A,ZNF706 61.06 0.00022 0.00785558935361217 GO:0051351 positive regulation of ligase activity biological_process 100 35 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CDC23,CDC27,CUL1,DCUN1D4,FZR1,GCLM,MID1IP1,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,UBA52,UBE2E1 19.63 0.00022 0.00785558935361217 GO:0051640 organelle localization biological_process 442 117 ABCE1,ACTR2,ANKRD53,AP1M2,AP3M2,AP3S1,ARF1,ARHGEF2,ARL6,ASUN,AURKA,BBS2,BET1,BRAF,BTBD9,BTK,C12orf4,CADPS2,CDC23,CDC42,CENPA,CENPQ,CHMP3,CHMP5,CHMP6,CLASP1,CLASP2,CLN3,CNIH1,CNIH2,CPLX2,CUL3,DCTN1,DCTN2,DCTN4,DNM1L,DOCK7,EEA1,EIF6,FES,FEZ1,FMN2,FNBP1L,GORASP1,HAP1,HDAC6,IL4R,KIF13A,KIF23,LAMTOR1,LAT,LLGL2,LRPPRC,LTV1,MAP1S,MAP4K2,MAP6,MCFD2,MEF2A,MLPH,MSTO1,MYH10,MYH9,NDE1,NLGN3,NUP98,NUSAP1,PAFAH1B1,PCM1,PDCD10,PFN2,PIK3CD,PIP5K1C,PPP6R3,PREB,PRKCZ,PTEN,PTK2,RAB1A,RAB27B,RAB5A,RAC2,RAP1A,RAP1B,RHOT1,RIMS1,SCFD1,SDAD1,SEC24A,SEC24B,SEC24D,SEC31A,SEH1L,SEPT5,SNAP23,SNAPIN,SPAG5,SPDL1,SPRY1,STK25,STX5,STXBP2,SYT1,SYT5,TERB2,TGFA,TMED2,TPGS1,TRAPPC12,UBE2B,UVRAG,VPS4A,WDR43,XPO1,YKT6,YWHAZ,ZAP70 86.78 0.00024 0.00853727272727273 GO:0051656 establishment of organelle localization biological_process 338 93 ABCE1,ACTR2,ANKRD53,AP1M2,AP3M2,AP3S1,ARF1,ARHGEF2,ARL6,BBS2,BET1,BRAF,BTBD9,CADPS2,CDC23,CDC42,CENPA,CENPQ,CHMP3,CHMP5,CHMP6,CLASP1,CLASP2,CLN3,CNIH1,CNIH2,CPLX2,CUL3,DCTN1,DCTN2,DCTN4,EEA1,EIF6,FEZ1,FMN2,FNBP1L,GORASP1,HAP1,KIF13A,KIF23,LLGL2,LRPPRC,LTV1,MAP1S,MAP4K2,MCFD2,MLPH,MYH10,MYH9,NDE1,NUSAP1,PAFAH1B1,PDCD10,PFN2,PIP5K1C,PPP6R3,PREB,PRKCZ,PTK2,RAB1A,RAB27B,RAB5A,RAP1A,RAP1B,RHOT1,RIMS1,SCFD1,SDAD1,SEC24A,SEC24B,SEC24D,SEC31A,SEH1L,SEPT5,SNAP23,SNAPIN,SPAG5,SPDL1,SPRY1,STK25,STX5,SYT1,SYT5,TERB2,TGFA,TMED2,TRAPPC12,UBE2B,VPS4A,WDR43,XPO1,YKT6,YWHAZ 66.36 0.00025 0.00885943396226415 GO:0045899 positive regulation of RNA polymerase II... biological_process 9 7 CAND1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,WNT10B 1.77 0.00028 0.00973881481481481 GO:0042451 purine nucleoside biosynthetic process biological_process 101 35 ACACA,ACAT1,ADA,ADK,AK2,AMD1,APRT,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CECR1,COASY,GBAS,GMPS,GUK1,HPRT1,IMPDH1,MAT2A,MT-ATP6,NME4,NME5,NME6,NME7,NME9,PANK1,PANK3,PANK4,PPCDC,SLC25A13,SURF1,TGFB1,TYW5 19.83 0.00028 0.00973881481481481 GO:0046129 purine ribonucleoside biosynthetic proce... biological_process 101 35 ACACA,ACAT1,ADA,ADK,AK2,AMD1,APRT,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CECR1,COASY,GBAS,GMPS,GUK1,HPRT1,IMPDH1,MAT2A,MT-ATP6,NME4,NME5,NME6,NME7,NME9,PANK1,PANK3,PANK4,PPCDC,SLC25A13,SURF1,TGFB1,TYW5 19.83 0.00028 0.00973881481481481 GO:0009163 nucleoside biosynthetic process biological_process 128 42 ACACA,ACAT1,ADA,ADK,AK2,AMD1,APRT,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CECR1,CMPK1,COASY,DCTD,GBAS,GMPS,GUK1,HPRT1,IMPDH1,MAT2A,MT-ATP6,NME4,NME5,NME6,NME7,NME9,PANK1,PANK3,PANK4,PDCL3,PPCDC,QTRT1,SLC25A13,SURF1,TGFB1,TK1,TYMS,TYW5,UPRT 25.13 0.00028 0.00973881481481481 GO:1901659 glycosyl compound biosynthetic process biological_process 128 42 ACACA,ACAT1,ADA,ADK,AK2,AMD1,APRT,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CECR1,CMPK1,COASY,DCTD,GBAS,GMPS,GUK1,HPRT1,IMPDH1,MAT2A,MT-ATP6,NME4,NME5,NME6,NME7,NME9,PANK1,PANK3,PANK4,PDCL3,PPCDC,QTRT1,SLC25A13,SURF1,TGFB1,TK1,TYMS,TYW5,UPRT 25.13 0.00028 0.00973881481481481 GO:0006363 termination of RNA polymerase I transcri... biological_process 31 15 CDK7,GTF2H2,GTF2H3,GTF2H5,MNAT1,POLR1D,POLR2E,POLR2H,POLR2K,TAF1A,TAF1B,TAF1C,TAF1D,TTF1,UBTF 6.09 0.00029 0.0100494095940959 GO:0010605 negative regulation of macromolecule met... biological_process 2264 506 AAAS,ABCE1,ACE,ACOD1,ACOT8,ADNP,AEBP1,AGO1,AGO2,AHR,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANXA2,ANXA4,ANXA7,APBB1,APOBEC3F,ARID4A,ARPP19,ASH1L,ATF2,ATF4,ATF7IP,ATOH8,ATR,ATRX,ATXN2,AURKB,AZIN2,BAG4,BAHCC1,BANP,BAX,BAZ2A,BBS2,BCLAF1,BIRC3,BIRC6,BIRC7,BPTF,BRCA1,BRD7,BUB1B,C1D,C1QBP,C3orf33,C4A,C4B,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CBX5,CCNT1,CD2BP2,CD44,CD46,CDC23,CDC27,CDC42,CDC6,CDK5RAP3,CEP192,CHAD,CHCHD3,CHORDC1,CIART,CIR1,CLN3,CLN8,CLTC,CNOT2,CNOT7,CNOT8,CNST,COL4A3,COPS2,CPEB1,CPEB3,CPNE1,CR1,CREM,CRYAB,CRYM,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTC1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAG1,DAPK1,DAPK3,DDX20,DEPDC1,DICER1,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DOT1L,DR1,DROSHA,DUSP16,DUSP9,DYNC1LI1,E2F7,EAPP,EGFR,EHMT1,EHMT2,EIF2AK2,EIF4A2,EIF4E,EIF6,ELF3,ELP2,EN1,EPRS,ERN2,ESR1,ETV6,ETV7,EXD1,EZH2,FARP1,FBXO7,FBXW11,FGFR1,FGFR1OP,FKBP6,FMN2,FOXJ1,FOXN3,FXR1,FZD6,FZR1,GATAD2A,GATAD2B,GCLC,GEN1,GFRA2,GIGYF2,GMFB,GMFG,GPC3,GRB7,GSK3B,GSTP1,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELB,HELLS,HESX1,HEYL,HHATL,HIPK3,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA7,HSF4,HSPA8,HUS1,IGF1R,IGF2BP3,IL1B,IL1R2,IMPACT,IPO8,IRAK1,IRF2,ITGAV,ITGB1BP1,ITGB8,ITM2C,JAZF1,JUND,KANK2,KAT2B,KAT6A,KLF16,KLHL40,KMT2D,L3MBTL1,LANCL2,LCMT1,LGR4,LHX9,LIF,LIG3,LIMD1,LIMK1,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,MAGED1,MALSU1,MAP2K5,MARVELD3,MASTL,MBD3,MDM2,MDM4,MEF2A,MEF2C,MEIS2,METTL14,MIER1,MLX,MORF4L1,MOSPD1,MPHOSPH10,MSX2,MTA3,MTDH,MTF2,MTOR,MVP,MXD3,MYB,MYF6,N4BP1,NAB1,NAT10,NCBP2,NCK1,NCOA2,NCOR1,NCOR2,NDC1,NDRG2,NEDD4L,NF1,NFE2L3,NFKBID,NIPBL,NKRF,NLRC5,NLRP12,NMI,NR2C1,NTRK3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OGT,OLFM1,OTULIN,OVOS2,PABPC1,PAFAH1B1,PAIP2,PAK2,PAQR3,PARP10,PARPBP,PAWR,PAX2,PAX4,PAXBP1,PBK,PCBP3,PDCD10,PDCL3,PDE2A,PDE4D,PELI1,PHF1,PHF12,PHF14,PIAS1,PIN1,PIWIL4,PLA2G10,PLCB1,PLK3,PODN,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PON1,POR,POT1,PPP1R1B,PPP2R1A,PRDM16,PRICKLE1,PRKAR2A,PRKCZ,PRMT3,PRR5L,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTBP2,PTEN,PTPN2,PTPN6,PTPRK,PTRH2,PUM2,PURA,RAD17,RAE1,RANBP2,RAP1A,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM4,RBMX,RBPJ,RECQL5,RFX5,RGN,RGS14,RGS3,RNF2,RNF4,RNF8,RNPS1,ROS1,RPS6KA1,RPS6KA6,RRP8,RTN4RL2,RUNX1T1,RXRA,SAP18,SDCBP,SEH1L,SEMA4D,SENP2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SF3B3,SFPQ,SIM2,SIRT2,SIRT5,SIRT6,SIX1,SIX3,SKIL,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCE1,SMC1A,SMYD2,SMYD3,SNAI3,SORBS3,SORL1,SOX6,SP3,SPINT2,SPOCK3,SPRY1,SRSF7,STAT6,STRAP,SUMO1,SUPT4H1,SYTL2,TARBP2,TAX1BP1,TBC1D10C,TBK1,TBL1XR1,TBPL2,TBX20,TBX3,TCERG1,TCF25,TCF7,TEX14,TFIP11,TFPI,TGFB1,TGIF1,THOC1,THY1,TIA1,TIGAR,TIPARP,TLK2,TLR9,TMBIM6,TMEFF2,TNRC18,TP63,TRA2B,TRIM29,TRIP12,TSC22D3,TTF1,TTK,UBA3,UBA52,UBE2B,UBE2E1,UCHL5,UFL1,UNK,USP3,USP4,USP7,USP9X,VEGFA,VIL1,WAC,WAPL,WFDC2,WHSC1,WNT10B,WNT11,WWC2,WWP1,WWTR1,XIAP,XPO1,XRCC3,XRCC5,YBX3,YWHAQ,ZBTB20,ZC3H12A,ZC3H8,ZCCHC11,ZEB1,ZNF148,ZNF207,ZNF219,ZNF224,ZNF253,ZNF254,ZNF280D,ZNF418 444.51 0.00030 0.0103577205882353 GO:0045930 negative regulation of mitotic cell cycl... biological_process 209 62 ANGEL2,ATF2,AURKA,BAX,BCL2,BRD7,BRINP1,BRINP2,BTG3,BUB1B,CDC6,CDK5RAP3,CENPJ,CHFR,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DNA2,DYNC1LI1,E2F7,EGFR,EZH2,FANCI,FBXO7,FHL1,FOXN3,GEN1,GIGYF2,HMGA2,HUS1,JADE1,KANK2,KNTC1,LCMT1,MDM2,MDM4,MTBP,MYO16,NAE1,NEK11,NME6,PCBP4,PLK3,PRMT1,PSMG2,PTEN,RAD17,RFWD3,SLF1,SMC1A,TEX14,TGFB1,TOM1L1,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 41.03 0.00031 0.0106637728937729 GO:0006260 DNA replication biological_process 349 95 ATR,ATRX,AURKB,BAZ1A,BRCA1,BRIP1,CCDC88A,CCNE2,CCT3,CCT7,CDC42,CDC6,CTC1,DBF4,DNA2,E2F7,EGF,EGFR,EHMT2,FAM111A,GLI1,GRHL2,HELB,HNRNPC,HNRNPU,HUS1,IGF1R,INO80,INO80E,KAT7,LIG3,LIG4,MAP2K4,MAP2K7,MAPKAPK5,MCM2,MCM8,MCMBP,MMS22L,NAP1L1,NASP,NAT10,NCOA6,NEK7,NOL8,NOP10,NPM2,NUCKS1,NUP98,NVL,ORC4,PARP2,PNKP,POLA1,POLA2,POLB,POLD3,POLD4,POLI,POLK,POT1,PPP2R1A,PRIM1,PURA,RAD17,RBBP4,RBBP6,RBBP7,RBBP8,RBMS1,RECQL5,REV1,RFC2,RFC4,RMI1,RPA3,RRM2B,SENP2,SLF1,SMC1A,SMG6,SSBP1,TBRG1,TCP1,TEFM,TGFB1,THOC1,TNKS,TOP2B,TOPBP1,TTF1,WAPL,WIZ,WRN,ZRANB3 68.52 0.00032 0.0109675912408759 GO:0043044 ATP-dependent chromatin remodeling biological_process 65 25 ACTL6A,ANP32A,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,GATAD2B,HDAC1,HDAC2,HNRNPC,ITGB3BP,MBD3,MIS18BP1,NASP,PSME4,RBBP4,RBBP7,RNF8,SMARCA5,SMARCAD1,SMARCD2,SMARCE1,SYCP3 12.76 0.00034 0.0115686231884058 GO:0051438 regulation of ubiquitin-protein transfer... biological_process 129 42 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CDC23,CDC27,CUL1,DCUN1D4,DYNC1LI1,FZR1,GEN1,LCMT1,LIMK1,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,TEX14,TTK,UBA52,UBE2E1,XRCC3,ZNF207 25.33 0.00034 0.0115686231884058 GO:0010948 negative regulation of cell cycle proces... biological_process 214 63 AURKA,AURKB,BAX,BCL2,BRCA1,BRD7,BUB1B,CDC6,CDK5RAP3,CENPJ,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DAB2IP,DDX39B,DNA2,DYNC1LI1,E2F7,EZH2,FANCI,FBXO7,FHL1,FOXN3,GEN1,GIGYF2,HMGA2,HORMAD1,HUS1,JADE1,KANK2,LCMT1,LIF,MDM1,MDM2,MDM4,MTBP,MYO16,NAE1,NME6,PCBP4,PLK3,PRMT1,PSMG2,PTEN,RAD17,RFWD3,SLF1,SMC1A,TEX14,THOC1,TMEM67,TOM1L1,TOPBP1,TP63,TTK,UBA52,VPS4A,WAPL,XRCC3,ZNF207,ZNF385A 42.02 0.00035 0.01173875 GO:0006446 regulation of translational initiation biological_process 76 28 AGO2,ATF4,BOLL,CDC123,DDX1,EIF1,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4G2,EIF4G3,EIF4H,EIF5B,IMPACT,MTIF2,NCBP2,PAIP2,POLR2G,RBM4,RPS6KB1,RPS6KB2,RXRA 14.92 0.00035 0.01173875 GO:0030036 actin cytoskeleton organization biological_process 557 142 ABI1,ABLIM2,ABLIM3,ABR,ACTG1,ACTN1,ACTR2,ACTR3C,AKAP2,ALOX15,ANTXR1,ARF1,ARHGAP26,ARHGAP6,ARHGEF15,ARHGEF2,ARPC1A,ARPC1B,ATP2C1,ATXN3,BAG4,BCAR1,BCAS3,BCL2,BRAF,CAPZA1,CARMIL2,CATIP,CCDC88A,CDC42,CDC42EP3,CELSR1,CFLAR,CLASP1,CLASP2,COBL,CORO2B,CORO7,CSF1R,CTNNA1,CUL3,CXADR,CXCL12,CYFIP1,DAAM1,DAPK3,EHD2,EPB41L3,EVL,FARP2,FAT1,FCHSD1,FES,FGD3,FGD4,FGD6,FHOD3,FLII,FMN1,FMN2,FMNL2,FOXJ1,FRMD3,FRMD6,FRY,FRYL,GMFB,GMFG,GSN,HSP90B1,ITGB1BP1,JAM3,KANK1,KIF23,KRAS,LCP1,LIMCH1,LIMK1,LLGL2,MEF2A,MEF2C,MINK1,MKLN1,MOB2,MTOR,MYH10,MYH9,MYO18A,MYO1B,MYOC,MYOZ3,NCK1,NEB,NF1,NISCH,NOX4,NTRK3,PAFAH1B1,PAK1,PAK3,PALLD,PARVG,PAWR,PDCD10,PDGFRB,PDLIM3,PDLIM7,PFN2,PICK1,PIP5K1A,PIP5K1C,PLEK2,PRKCZ,PTK2B,RAC2,RACGAP1,RAP1GDS1,RHOF,RUFY3,SDAD1,SDCBP,SORBS2,SORBS3,SPTB,SPTBN1,SPTBN4,SYNPO,SYNPO2,TGFB1,TGFBR1,TLN1,TMEFF2,TNNT2,TNXB,TRIOBP,TRIP10,TRPM7,TTC17,TWF1,VIL1,WNT11,ZYX 109.36 0.00035 0.01173875 GO:0043488 regulation of mRNA stability biological_process 141 45 AKT1,ANGEL2,ANP32A,BOLL,CPEB3,EXOSC8,HNRNPC,HNRNPD,HNRNPU,HSPA8,METTL14,MTOR,PABPC1,PARN,PCBP4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PUM2,SERBP1,THRAP3,TNPO1,UBA52,XPO1,XRN1,YBX3,YWHAZ,ZC3H12A 27.68 0.00035 0.01173875 GO:0032886 regulation of microtubule-based process biological_process 145 46 ANKRD53,ARHGEF2,ARMC4,ATAT1,AURKA,BBS2,BORA,BRCA1,C16orf45,CAMSAP3,CDC42,CENPJ,CFAP20,CHMP3,CHMP5,CHORDC1,CLASP1,CLASP2,CLIP1,CLTC,CYLD,DCTN1,DNAH11,ECT2,EML2,FES,FKBP4,GEN1,GSK3B,HDAC6,MAP6D1,MDM1,MID1IP1,PAFAH1B1,PHLDB1,PLK4,RACGAP1,RNF4,SENP6,SIRT2,SLAIN2,SPAG5,STMN4,TMEM67,XPO1,XRCC3 28.47 0.00036 0.011946148409894 GO:0016570 histone modification biological_process 424 112 ACTL6A,APBB1,ARID4A,ASH1L,ATF2,ATRX,ATXN7,AURKA,AURKB,BAP1,BAZ1A,BAZ2A,BRCA1,BRD7,CHD3,CHTOP,CTBP1,CTR9,CUL4B,DDB1,DOT1L,DR1,EHMT1,EHMT2,ELP4,ENY2,EYA3,EYA4,EZH2,H2AFY,HAT1,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HMGA2,HSF4,IL1B,JADE1,JMJD1C,JMJD6,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KDM1B,KDM5D,KDM6A,KDM7A,KMT2A,KMT2D,KMT2E,LEO1,LIF,MAP3K12,MAPK8,MBD3,MEAF6,MED24,MORF4L1,MTA1,MTA3,MTF2,MYB,MYSM1,NAA60,NCOA1,NCOA2,NEK11,NIPBL,OGT,PAX7,PAXBP1,PHF1,PHF20,PHF21A,PRDM16,PRMT1,PRMT3,PRMT5,PWP1,RBBP4,RBBP7,RNF2,RNF8,SAP18,SFPQ,SIRT2,SIRT6,SMAD4,SMARCAD1,SMYD2,SMYD3,TBL1XR1,TGFB1,TRIP12,UBE2B,UBE2E1,USP15,USP3,USP34,VEGFA,WAC,WDR75,WHSC1,WHSC1L1,YEATS4,ZNF451 83.25 0.00036 0.011946148409894 GO:1901988 negative regulation of cell cycle phase ... biological_process 153 48 AURKA,BAX,BCL2,BRD7,BUB1B,CDC6,CDK5RAP3,CENPJ,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DNA2,DYNC1LI1,E2F7,EZH2,FANCI,FBXO7,FHL1,FOXN3,GEN1,GIGYF2,HMGA2,HUS1,JADE1,KANK2,LCMT1,MDM2,MDM4,MYO16,NAE1,PCBP4,PLK3,PRMT1,PSMG2,PTEN,RAD17,RFWD3,SLF1,TEX14,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 30.04 0.00036 0.011946148409894 GO:0030397 membrane disassembly biological_process 48 20 AAAS,CCNB2,CTDNEP1,DCTN1,LPIN1,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAFAH1B1,RAE1,RANBP2,SEH1L 9.42 0.00038 0.0125213333333333 GO:0051081 nuclear envelope disassembly biological_process 48 20 AAAS,CCNB2,CTDNEP1,DCTN1,LPIN1,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAFAH1B1,RAE1,RANBP2,SEH1L 9.42 0.00038 0.0125213333333333 GO:0051443 positive regulation of ubiquitin-protein... biological_process 95 33 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CDC23,CDC27,CUL1,DCUN1D4,FZR1,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,UBA52,UBE2E1 18.65 0.00039 0.0128059090909091 GO:0070507 regulation of microtubule cytoskeleton o... biological_process 126 41 ANKRD53,ARHGEF2,ATAT1,AURKA,BORA,BRCA1,C16orf45,CAMSAP3,CDC42,CENPJ,CHMP3,CHMP5,CHORDC1,CLASP1,CLASP2,CLIP1,CLTC,CYLD,DCTN1,ECT2,EML2,FES,FKBP4,GEN1,HDAC6,MAP6D1,MDM1,MID1IP1,PAFAH1B1,PHLDB1,PLK4,RACGAP1,RNF4,SENP6,SIRT2,SLAIN2,SPAG5,STMN4,TMEM67,XPO1,XRCC3 24.74 0.00040 0.0130430555555556 GO:0009889 regulation of biosynthetic process biological_process 4190 898 ABCA2,ABLIM3,ACAD8,ACADVL,ACOD1,ACOT8,ACTL6A,ACTN1,ADCY4,ADCYAP1,ADGRD1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AKAP12,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,APLP1,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ARL2BP,ARPP19,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCL2,BCLAF1,BLZF1,BMPR1B,BOLL,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C12orf65,C14orf166,C1D,C1QBP,C3orf33,CACNA1A,CALM1,CAMK2A,CAMTA1,CAND1,CAPRIN1,CARF,CASK,CBX5,CCDC59,CCDC88A,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CD81,CDC123,CDC42,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLK2,CLTC,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB1,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYBB,CYLD,DAB2IP,DAPK1,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DDX6,DENND4A,DEPDC1,DHCR7,DHFR,DICER1,DLAT,DLD,DMRT2,DMRTA1,DMTF1,DNA2,DNAJC1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DTX1,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,EPRS,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FCER2,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FUS,FXR1,FZD6,GABBR1,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GIGYF2,GIPR,GLA,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRB7,GRHL1,GRHL2,GRM7,GRM8,GSK3B,GSTP1,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HHATL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,HTR2B,HUS1,ICE1,ICE2,IGF1R,IGF2BP3,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA2,ITGA6,ITGAV,ITGB1BP1,ITGB3BP,ITM2C,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIG3,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALSU1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K2,MAPK8,MAPKAPK5,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,METTL14,MGA,MID1IP1,MIER1,MKNK1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTG1,MTIF2,MTOR,MTRF1,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NAT10,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NEK7,NF1,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NGDN,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NOS3,NOX1,NOX4,NPAS3,NPM2,NR2C1,NR3C1,NR3C2,NSMAF,NSUN4,NTRK3,NUCKS1,NUP107,NUP35,NVL,OGFOD1,OGT,ONECUT2,OPRM1,ORMDL2,ORMDL3,OTULIN,PABPC1,PAIP2,PAK3,PARP10,PARP14,PAWR,PAX2 822.66 0.00040 0.0130430555555556 GO:0006283 transcription-coupled nucleotide-excisio... biological_process 73 27 AQR,CDK7,COPS2,COPS3,CUL4B,DDB1,GTF2H2,GTF2H3,GTF2H5,HMGN1,LIG3,MNAT1,POLD3,POLD4,POLK,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,RFC2,RFC4,RPA3,UBA52,USP7,UVSSA 14.33 0.00041 0.0133228719723183 GO:0034605 cellular response to heat biological_process 107 36 AAAS,ARPP21,ATR,ATXN3,BAG4,CAMK2A,CAMK2G,CHORDC1,CRYAB,FKBP4,GSK3B,HDAC2,HSPA8,HSPH1,IRAK1,MKI67,MTOR,NDC1,NF1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,RBBP7,RPA3,SEH1L,STAC,TFEC 21.01 0.00044 0.0141508219178082 GO:0006305 DNA alkylation biological_process 66 25 ATF7IP,ATRX,BAZ2A,BRCA1,EHMT1,EHMT2,EZH2,FKBP6,GATAD2A,GATAD2B,GRHL2,GSK3B,HELLS,KDM1B,KMT2A,KMT2E,MBD3,MTRR,PICK1,PIK3CA,PIWIL4,PRMT5,RLF,TDRD5,USP7 12.96 0.00044 0.0141508219178082 GO:0006306 DNA methylation biological_process 66 25 ATF7IP,ATRX,BAZ2A,BRCA1,EHMT1,EHMT2,EZH2,FKBP6,GATAD2A,GATAD2B,GRHL2,GSK3B,HELLS,KDM1B,KMT2A,KMT2E,MBD3,MTRR,PICK1,PIK3CA,PIWIL4,PRMT5,RLF,TDRD5,USP7 12.96 0.00044 0.0141508219178082 GO:0042558 pteridine-containing compound metabolic ... biological_process 32 15 ALDH1L1,ATIC,DHFR,FTCD,GART,GGH,MTHFD1,MTHFD2L,MTRR,PCBD1,PTS,QDPR,SHMT2,SLC25A32,TYMS 6.28 0.00045 0.0144230375426621 GO:0042455 ribonucleoside biosynthetic process biological_process 119 39 ACACA,ACAT1,ADA,ADK,AK2,AMD1,APRT,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CECR1,CMPK1,COASY,GBAS,GMPS,GUK1,HPRT1,IMPDH1,MAT2A,MT-ATP6,NME4,NME5,NME6,NME7,NME9,PANK1,PANK3,PANK4,PDCL3,PPCDC,QTRT1,SLC25A13,SURF1,TGFB1,TYW5,UPRT 23.36 0.00047 0.0150128231292517 GO:0009301 snRNA transcription biological_process 70 26 ASUN,CCNT1,CCNT2,CDK7,CPSF3L,ELL2,GTF2B,ICE1,ICE2,INTS10,INTS12,INTS6,INTS8,NCBP2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POU2F2,RPRD2,SNAPC3,SNAPC4,SP1,ZC3H8,ZNF143 13.74 0.00049 0.0155459121621622 GO:0042795 snRNA transcription from RNA polymerase ... biological_process 70 26 ASUN,CCNT1,CCNT2,CDK7,CPSF3L,ELL2,GTF2B,ICE1,ICE2,INTS10,INTS12,INTS6,INTS8,NCBP2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POU2F2,RPRD2,SNAPC3,SNAPC4,SP1,ZC3H8,ZNF143 13.74 0.00049 0.0155459121621622 GO:0043487 regulation of RNA stability biological_process 147 46 AKT1,ANGEL2,ANP32A,BOLL,CPEB3,EXOSC8,HNRNPC,HNRNPD,HNRNPU,HSPA8,METTL14,MTOR,PABPC1,PARN,PCBP4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PUM2,SERBP1,SMG6,THRAP3,TNPO1,UBA52,XPO1,XRN1,YBX3,YWHAZ,ZC3H12A 28.86 0.00050 0.015756711409396 GO:0006353 DNA-templated transcription, termination biological_process 100 34 CDK7,CHTOP,CSTF1,CSTF3,DDX39B,FIP1L1,GTF2H2,GTF2H3,GTF2H5,MNAT1,NCBP2,NUDT21,PABPN1,POLDIP3,POLR1D,POLR2E,POLR2H,POLR2K,PRMT5,RNPS1,SNRPE,SNRPF,SRSF11,SRSF5,SRSF7,TAF1A,TAF1B,TAF1C,TAF1D,THOC1,THOC2,THOC7,TTF1,UBTF 19.63 0.00050 0.015756711409396 GO:0045898 regulation of RNA polymerase II transcri... biological_process 12 8 ATF7IP,CAND1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,WNT10B 2.36 0.00051 0.0159647 GO:0009892 negative regulation of metabolic process biological_process 2519 556 AAAS,ABCE1,ACADVL,ACE,ACOD1,ACOT8,ADCYAP1,ADNP,ADORA1,AEBP1,AGO1,AGO2,AHR,AIP,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANKLE2,ANXA2,ANXA4,ANXA7,APBB1,APLP1,APOBEC3F,ARID4A,ARPP19,ASH1L,ATF2,ATF4,ATF7IP,ATOH8,ATP2B4,ATR,ATRX,ATXN2,ATXN7,AURKB,AZIN2,BAG4,BAHCC1,BANP,BAX,BAZ2A,BBS2,BCAS3,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BPTF,BRCA1,BRD7,BUB1B,C1D,C1QBP,C3orf33,C4A,C4B,CABIN1,CACNA1A,CALM1,CAMSAP3,CAND1,CAPRIN1,CARD16,CASP8,CBX5,CCNT1,CD2BP2,CD44,CD46,CDC23,CDC27,CDC42,CDC6,CDK5RAP3,CEP192,CHAD,CHCHD3,CHORDC1,CIART,CIR1,CLK2,CLN3,CLN8,CLTC,CNOT2,CNOT7,CNOT8,CNST,COL4A3,COPS2,CPEB1,CPEB3,CPNE1,CR1,CREM,CRYAB,CRYM,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTC1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAG1,DAPK1,DAPK3,DAPL1,DDX20,DEPDC1,DICER1,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DOT1L,DR1,DROSHA,DUSP16,DUSP9,DYNC1LI1,E2F7,EAPP,EGFR,EHMT1,EHMT2,EIF2AK2,EIF4A2,EIF4E,EIF6,ELF3,ELP2,EN1,EPRS,ERN2,ESR1,ETV6,ETV7,EXD1,EZH2,FARP1,FBXO7,FBXW11,FGFR1,FGFR1OP,FKBP6,FMN2,FOXJ1,FOXN3,FRY,FXR1,FZD6,FZR1,GABBR1,GATAD2A,GATAD2B,GBAS,GCLC,GEN1,GFRA2,GIGYF2,GLA,GMFB,GMFG,GMIP,GPC3,GRB10,GRB7,GRM7,GRM8,GSK3B,GSTP1,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELB,HELLS,HESX1,HEYL,HHATL,HIPK3,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA7,HSF4,HSPA8,HTR2B,HUS1,IGF1R,IGF2BP3,IL1B,IL1R2,IMPACT,IPO8,IRAK1,IRF2,ITGAV,ITGB1BP1,ITGB8,ITM2C,JAZF1,JUND,KANK2,KAT2B,KAT6A,KLF16,KLHL40,KMT2D,L3MBTL1,LANCL2,LCMT1,LGR4,LHX9,LIF,LIG3,LIMD1,LIMK1,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,LTF,MAGED1,MALSU1,MAP2K5,MARVELD3,MASTL,MBD3,MDM2,MDM4,MEF2A,MEF2C,MEIS2,METTL14,MIDN,MIER1,MLX,MORF4L1,MOSPD1,MPHOSPH10,MSX2,MTA3,MTDH,MTF2,MTOR,MVP,MXD3,MYB,MYF6,N4BP1,NAB1,NAT10,NCBP2,NCK1,NCOA2,NCOR1,NCOR2,NDC1,NDRG2,NEDD4L,NF1,NFE2L3,NFKBID,NIPBL,NKRF,NLRC5,NLRP12,NMI,NOS3,NR2C1,NTRK3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OAZ1,OAZ2,OGT,OLFM1,OPRM1,ORMDL2,ORMDL3,OTULIN,OVOS2,PABPC1,PAFAH1B1,PAIP2,PAK2,PAQR3,PARP10,PARPBP,PAWR,PAX2,PAX4,PAXBP1,PBK,PCBP3,PDCD10,PDCL3,PDE2A,PDE4D,PDE6D,PDZD3,PELI1,PHF1,PHF12,PHF14,PIAS1,PIN1,PIWIL4,PLA2G10,PLCB1,PLK3,PODN,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PON1,POR,POT1,PPP1R12A,PPP1R1B,PPP1R2P3,PPP1R8,PPP2R1A,PRDM16,PRICKLE1,PRKAR2A,PRKCZ,PRMT3,PRR5L,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTBP2,PTEN,PTPN2,PTPN6,PTPRK,PTRH2,PUM2,PURA,RAD17,RAE1,RANBP2,RAP1A,RAPGEF2,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM4,RBMX,RBPJ,RECQL5,RFX5,RGN,RGS14,RGS3,RNF2,RNF4,RNF8,RNH1,RNPS1,ROS1,RPS19,RPS6KA1,RPS6KA6,RRP8,RTN4RL2,RUNX1T1,RXRA,SAP18,SCAP,SDCBP,SEH1L,SEMA4D,SENP2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SF3B3,SFPQ,SIM2,SIRT2,SIRT5,SIRT6,SIX1,SIX3,SKIL,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCE1,SMC1A,SMYD2,SMYD3,SNAI3,SORBS3,SORL1,SOX6,SP3,SPINT2,SPOCK3,SPRY1,SRSF7,STAT6,STRAP,SUMO1,SUPT4H1,SYTL2,TAB2,TAB3,TARBP2,TAX1BP1,TBC1D10C,TBK1,TBL1XR1,TBPL2,TBX20,TBX3,TCERG1,TCF25,TCF7,TEX14,TFIP11,TFPI,TGFB1,TGIF1,THOC1,THY1,TIA1,TIGAR,TIPARP,TLK2,TLR9,TMBIM6,TMED2,TMEFF2,TNK2,TNNI3,TNNT2 494.58 0.00051 0.0159647 GO:0006998 nuclear envelope organization biological_process 85 30 AAAS,ANKLE2,ASUN,CCNB2,CTDNEP1,DCTN1,DMPK,LPIN1,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PAFAH1B1,PPP2R1A,PPP2R2A,RAE1,RANBP2,SEH1L,SUMO1,TOR1AIP1,TOR1AIP2,UBXN2B 16.69 0.00052 0.0161699337748344 GO:0006521 regulation of cellular amino acid metabo... biological_process 63 24 ATP2B4,DUOXA1,OAZ1,OAZ2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4 12.37 0.00052 0.0161699337748344 GO:0033045 regulation of sister chromatid segregati... biological_process 49 20 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,H2AFY,LCMT1,NSMCE2,PSMG2,SLF1,TEX14,TTK,XRCC3,ZNF207 9.62 0.00053 0.0163187868852459 GO:0033047 regulation of mitotic sister chromatid s... biological_process 49 20 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,H2AFY,LCMT1,NSMCE2,PSMG2,SLF1,TEX14,TTK,XRCC3,ZNF207 9.62 0.00053 0.0163187868852459 GO:0033365 protein localization to organelle biological_process 730 179 ACAP2,AIP,AKT1,ANK2,ARFRP1,ARL1,ARL2BP,ASUN,ATP9B,ATR,ATRX,AURKA,AURKB,BANP,BAX,BBS2,BCL2,BICD1,BUB1B,CASP8,CCDC14,CD81,CDH1,CDK5RAP3,CENPA,CEP57,CSE1L,CTDNEP1,CYLD,DAB2IP,DAG1,DCTN2,DNAJA1,DNM1L,DYRK2,ECT2,EGF,EGFR,ESR1,EZH2,FAF1,FBXO7,FBXW11,FYB,GAK,GCC2,GET4,GNPTG,GOLGA4,GSK3B,H2AFY,HDAC8,HGS,IL1B,IMMP2L,IPO11,IPO8,IPO9,KANK1,KAT7,KDELR2,KIAA0753,LIF,LITAF,LZTS2,MAPK8,MARCH5,MDM2,MFF,MTBP,MTOR,MTX1,MTX2,MTX3,NAGPA,NCKIPSD,NF1,NLRP12,NMT1,NOP58,NRAS,NUP107,NUP155,NUP205,NUP35,NUP50,NUP54,NUP58,NUP98,OSBPL8,PAQR3,PARP10,PCM1,PDE2A,PEX16,PEX3,PEX5L,PIK3R2,PIN1,PLRG1,POLA2,POT1,PPM1B,PRICKLE1,PTTG1IP,RAB3GAP2,RAE1,RANBP2,RANBP6,RBCK1,RBPMS,RGPD1,RGPD5,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RYR2,SEC61B,SEC63,SIX1,SIX3,SMAD4,SNX16,SORL1,SPAG5,SPDL1,SPRN,SPTBN1,SRI,SRP19,SSR3,SUMO1,SYNE1,TBC1D10C,TGFB1,TGFBR1,TIMM10B,TIMM23B,TIMM50,TLR7,TLR9,TNKS,TNPO1,TOMM20,TOR1AIP1,TOR1AIP2,TP63,TRAPPC8,TRIM29,TRIP6,UBA52,UBAC2,VPS13A,VPS13C,VPS36,WAPL,WWTR1,XPO1,YWHAQ,YWHAZ,ZC3H12A,ZFYVE16 143.33 0.00053 0.0163187868852459 GO:0038093 Fc receptor signaling pathway biological_process 213 62 ABI1,ACTG1,ACTR2,ARPC1A,ARPC1B,BTK,CALM1,CD247,CD3G,CDC42,CHUK,CLEC4E,CUL1,CYFIP1,FBXW11,FCGR1B,KRAS,LAT,LIMK1,MALT1,MAP2K4,MAP2K7,MAPK8,MYO10,MYO1G,NCK1,NCKIPSD,NFATC1,NRAS,PAK1,PAK2,PIGR,PIK3CA,PIK3CB,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTK2,SOS1,TAB2,TAB3,UBA52,UBE2V1,VAV1 41.82 0.00054 0.0165723529411765 GO:0006892 post-Golgi vesicle-mediated transport biological_process 89 31 ANK3,AP1G1,ARF1,ARFRP1,BBS1,BBS2,BLZF1,C16orf62,CNST,CORO7,EXOC1,GAK,GCC2,GOLGA4,GOLGA7,KIF13A,KLHL20,LYPLA1,MON2,MYO1B,OSBPL5,PKDCC,RP2,SCFD1,SNAP23,SORL1,SPTBN1,VAMP4,VPS13A,VPS13C,VPS54 17.47 0.00055 0.0168242671009772 GO:0031326 regulation of cellular biosynthetic proc... biological_process 4151 888 ABCA2,ABLIM3,ACAD8,ACADVL,ACOD1,ACOT8,ACTL6A,ACTN1,ADCY4,ADCYAP1,ADGRD1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AKAP12,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,APLP1,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ARL2BP,ARPP19,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCL2,BCLAF1,BLZF1,BMPR1B,BOLL,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C12orf65,C14orf166,C1D,C1QBP,C3orf33,CACNA1A,CALM1,CAMK2A,CAMTA1,CAND1,CAPRIN1,CARF,CASK,CBX5,CCDC59,CCDC88A,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CD81,CDC123,CDC42,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLK2,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB1,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYBB,CYLD,DAB2IP,DAPK1,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DDX6,DENND4A,DEPDC1,DHFR,DICER1,DLAT,DLD,DMRT2,DMRTA1,DMTF1,DNA2,DNAJC1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DTX1,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,EPRS,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FUS,FXR1,FZD6,GABBR1,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GIGYF2,GIPR,GLA,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRB7,GRHL1,GRHL2,GRM7,GRM8,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HHATL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,HTR2B,HUS1,ICE1,ICE2,IGF1R,IGF2BP3,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA2,ITGA6,ITGB1BP1,ITGB3BP,ITM2C,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIG3,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALSU1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K2,MAPK8,MAPKAPK5,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,METTL14,MGA,MID1IP1,MIER1,MKNK1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTG1,MTIF2,MTOR,MTRF1,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NAT10,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NEK7,NF1,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NGDN,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NOS3,NOX4,NPAS3,NPM2,NR2C1,NR3C1,NR3C2,NSMAF,NSUN4,NTRK3,NUCKS1,NUP107,NUP35,NVL,OGFOD1,OGT,ONECUT2,OPRM1,ORMDL2,ORMDL3,OTULIN,PABPC1,PAIP2,PAK3,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1 815.01 0.00057 0.0173794480519481 GO:0006354 DNA-templated transcription, elongation biological_process 124 40 BRD4,CCNT1,CCNT2,CDK7,CTR9,DDX39B,EAPP,ELL2,ELP2,ELP4,ENY2,EZH2,GTF2B,GTF2H2,GTF2H3,GTF2H5,HMGN1,LEO1,MNAT1,NCBP2,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,RECQL5,RNF8,SUPT4H1,TAF1A,TAF1B,TAF1C,TAF1D,TAF2,TCEA2,TCEB1,THOC1,THOC7,UBTF,ZNF326 24.35 0.00058 0.0176271197411003 GO:0009108 coenzyme biosynthetic process biological_process 132 42 ACACA,ACAT1,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,ATIC,COASY,COQ4,DHFR,DLAT,DLD,ELOVL6,ELOVL7,FLAD1,GART,HACD1,MAT2A,MOCS1,MTHFD1,MTHFD2L,NADK,NADSYN1,NDUFA9,NMNAT3,NMRK1,PANK1,PANK3,PANK4,PCBD1,PDHB,PDK3,PDSS1,PDXK,PPCDC,PPT2,PTS,QDPR,SCD5,TECR 25.92 0.00059 0.0178731935483871 GO:0007018 microtubule-based movement biological_process 223 64 ACTR2,ADCY10,AP3M2,AP3S1,ARMC4,BBS2,BICD1,CABYR,CCDC114,CDC42,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CLN3,CLTA,DCTN1,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DPCD,DYNC1I2,DYNC1LI1,FMN2,HAP1,HDAC6,HSPB11,HYDIN,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KTN1,LRPPRC,MAP1S,NDE1,NME5,OFD1,OPA1,PAFAH1B1,PCM1,PRKCZ,RAB1A,RACGAP1,RHOT1,ROPN1L,RPGR,RSPH9,SNAPIN,SPAG16,SPG7,SSX2IP,TTC21B,WDR43 43.78 0.00067 0.0202314147909968 GO:0006361 transcription initiation from RNA polyme... biological_process 33 15 CDK7,GTF2H2,GTF2H3,GTF2H5,MNAT1,POLR1D,POLR2E,POLR2H,POLR2K,TAF1A,TAF1B,TAF1C,TAF1D,TTF1,UBTF 6.48 0.00068 0.0202726349206349 GO:0006999 nuclear pore organization biological_process 15 9 AHCTF1,NDC1,NUP107,NUP205,NUP35,NUP54,NUP98,RTN4,SEH1L 2.95 0.00068 0.0202726349206349 GO:0070816 phosphorylation of RNA polymerase II C-t... biological_process 15 9 BRD4,CCNC,CCNL2,CCNT1,CCNT2,CDK12,CDK13,FAM58A,GTF2H3 2.95 0.00068 0.0202726349206349 GO:1900034 regulation of cellular response to heat biological_process 75 27 AAAS,ATR,BAG4,CAMK2A,CAMK2G,CHORDC1,CRYAB,FKBP4,GSK3B,HSPA8,HSPH1,MTOR,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,RPA3,SEH1L 14.73 0.00068 0.0202726349206349 GO:0051649 establishment of localization in cell biological_process 2551 561 AAAS,ABAT,ABCA2,ABCE1,ABR,ACACA,ACTN1,ACTR2,ADCYAP1,ADORA1,ADPRHL1,AGFG1,AIP,AKAP12,AKAP3,AKT1,AKTIP,ANK2,ANK3,ANKRD53,ANP32A,ANXA2,ANXA4,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,ARF1,ARFGAP2,ARFRP1,ARHGEF2,ARL1,ARL2BP,ARL6,ASPSCR1,ATG3,ATG4B,ATL2,ATP2C1,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0D1,ATP7B,ATP9B,BAIAP3,BAX,BBS1,BBS2,BCAS3,BCL2,BET1,BICD1,BLK,BLZF1,BOK,BRAF,BTBD9,BTK,C12orf4,C16orf62,C1QTNF5,C2CD5,C5AR2,CACNA1A,CACNA1C,CACNA1H,CACNA2D1,CACNB3,CADPS2,CALM1,CAMK2A,CAMK2G,CASK,CASP8,CD14,CD74,CD9,CDC23,CDC42,CDH1,CENPA,CENPQ,CEP290,CEP57,CES1,CHD7,CHMP3,CHMP5,CHMP6,CHRNA3,CHRNA6,CHRNA7,CHTOP,CLASP1,CLASP2,CLEC4E,CLEC5A,CLN3,CLTA,CLTC,CLU,CNIH1,CNIH2,CNST,COG2,COG5,COPA,COPB1,CORO7,CPLX2,CPT2,CRHBP,CRYAB,CSE1L,CSF1R,CTDSPL2,CUL3,CUX1,CXCL12,CYLD,DAB2IP,DAG1,DCTN1,DCTN2,DCTN4,DCTN6,DDX20,DDX39B,DENND1B,DNAJC1,DNAJC13,DNM1L,DPH3,DSCR3,DUSP16,DYNC1I2,DYRK2,ECT2,EEA1,EGF,EGFR,EHD2,EIF4E,EIF6,ENY2,EPG5,ERC1,ERO1A,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,EXPH5,FAF1,FAM21A,FBXO22,FBXO7,FBXW11,FES,FEZ1,FGFR1,FIP1L1,FMN2,FNBP1L,FYB,GAK,GBP5,GCC2,GCGR,GDF9,GGA1,GIPR,GLS,GLS2,GNPTG,GOLGA4,GOLGA7,GORASP1,GPIHBP1,GRM7,GSK3B,HAP1,HDAC1,HDAC6,HGS,HGSNAT,HNRNPA2B1,HOMER3,HOOK1,HSP90B1,HSPA8,HSPB11,HSPD1,HTR2B,ICA1,ICE1,IL1B,IL1R2,IL4R,IMMP2L,IPO11,IPO8,IPO9,ITGB1BP1,ITPR1,KANK1,KCNB1,KDELR2,KIF13A,KIF15,KIF1A,KIF1BP,KIF23,KLHL20,LAMP2,LAT,LCN2,LCP1,LDLRAP1,LGR4,LIF,LITAF,LLGL2,LRP6,LRPPRC,LTV1,LYPLA1,LYST,LZTS2,M6PR,MALT1,MAP1S,MAP4K2,MAPK8,MCFD2,MCUR1,MDM2,MEF2C,MFF,MGRN1,MIA3,MIDN,MLPH,MON2,MPPE1,MT-ATP6,MTOR,MTX1,MTX2,MTX3,MYH10,MYH9,MYO10,MYO18A,MYO1B,MYO1G,NAGPA,NAPB,NAPG,NCBP2,NCKIPSD,NDC1,NDE1,NF1,NISCH,NLRP12,NMT1,NOP58,NOX5,NPLOC4,NRXN1,NTRK2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NUSAP1,NXF3,OAZ1,OAZ2,OPA1,OPRK1,OPRM1,OSBPL5,P2RX5,P2RY12,PABPN1,PACS2,PAFAH1B1,PAK1,PAN3,PARP10,PCK2,PCM1,PCSK5,PDCD10,PDE2A,PDE4D,PDZK1,PECAM1,PEX16,PEX3,PEX5L,PFN2,PICK1,PIK3C3,PIK3CD,PIK3R2,PIP5K1A,PIP5K1C,PITPNB,PKDCC,PLCB1,PLCD4,PLK3,PNPT1,POLA2,POLDIP3,POU2F2,PPFIA2,PPFIA4,PPM1B,PPP1CC,PPP1R12A,PPP6R3,PPY,PREB,PRICKLE1,PRKCZ,PRR5L,PSIP1,PTK2,PTK2B,PTPN6,PTPRN,PTTG1IP,RAB11FIP2,RAB1A,RAB27B,RAB2A,RAB2B,RAB3GAP2,RAB3IP,RAB5A,RABGAP1L,RAC2,RACGAP1,RAE1,RALB,RANBP2,RANBP3,RANBP6,RAP1A,RAP1B,RAPGEF4,RASA3,RBCK1,RBM4,RBMX2,RBPJ,RBPMS,RGPD1,RGPD5,RGS14,RHOT1,RIC1,RIMS1,RNPS1,RP2,RPGR,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RSRC1,RUFY3,RUNDC1,RYR2,RYR3,SCAMP5,SCFD1,SCFD2,SCRN3,SCYL2,SDAD1,SDCBP,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC61B,SEC63,SEH1L,SEPP1,SEPT5,SERP1,SERPINA3,SGSM1,SGSM3,SHFM1,SIDT2,SIL1,SIX3,SLC1A3,SLC1A7,SLC22A2,SLC25A13,SLC25A30,SLC38A2,SLC8B1,SMAD2,SMAD4,SMG1,SMG6,SNAP23,SNAPIN,SNRPE,SNRPF,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SORL1,SPAG5,SPAG9,SPDL1,SPG7,SPRN,SPRY1,SPTB,SPTBN1,SPTBN4,SRI,SRP19,SRSF11,SRSF5,SRSF7,SSR1,SSR2,SSR3,SSX2IP,STAM,STAR,STARD4,STK25,STX5,STX8,STXBP2,STXBP4,SYN2,SYT1,SYT5,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TBRG1,TBX3,TERB2,TF,TFR2,TGFA,TGFB1,TGFBR1 500.86 0.00069 0.0204409779179811 GO:0009408 response to heat biological_process 153 47 AAAS,AKT1,ARPP21,ATR,ATXN3,BAG4,CAMK2A,CAMK2G,CD14,CHORDC1,CRYAB,CXCL12,DNAJA1,FKBP4,GCLC,GSK3B,HDAC2,HSPA8,HSPD1,HSPH1,IRAK1,MAP2K7,MKI67,MTOR,NDC1,NF1,NOS3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PSIP1,RAE1,RANBP2,RBBP7,RPA3,RPS6KB1,SEH1L,STAC,TFEC,TGFB1I1 30.04 0.00069 0.0204409779179811 GO:0044712 single-organism catabolic process biological_process 2411 532 ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABR,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOT8,ACOX3,ACOXL,ACSF3,ADA,ADCYAP1,ADORA1,ADPGK,ADPRHL1,AGFG1,AHSA2,AK6,AKR1A1,AKT1,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,AMBRA1,AMDHD2,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANGPTL3,APOBEC3F,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ASPG,ATAD1,ATF7IP,ATG16L2,ATG3,ATG4B,ATL2,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATRX,BAG4,BCAS3,BCKDHB,BCKDK,BMS1,BNIP2,BPTF,BRIP1,BUB1B,CALCOCO2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CD44,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDK7,CECR1,CHAC2,CHD1,CHD2,CHD3,CHD6,CHMP3,CHN1,CHTOP,CLN3,CLU,COL4A3,COL4A5,COL6A1,COL6A5,COL6A6,CPS1,CPT1C,CPT2,CRBN,CROT,CRYM,CSNK2A1,CSNK2A2,CUL3,CYP2A6,CYP4F12,CYTH4,DAB2IP,DBT,DCXR,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHX15,DHX40,DHX57,DLD,DMC1,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH9,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DNM3,DOCK4,DOCK7,DPYS,DQX1,DYNC1LI1,ECT2,EDEM3,EGF,EGFR,EI24,EIF2S3,EIF4A1,EIF4A2,EIF5B,EIF6,ELMOD3,ENO4,ENOSF1,ENPP2,ENTPD4,EPG5,EPHA4,EPS8L1,ERCC6L2,ESD,ETFA,EXOC1,EXOC4,EZH2,FABP5,FAM13B,FARP1,FARP2,FBXO7,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FNBP1,FNBP1L,FRS2,FTCD,FUT1,FUT8,FUT9,GALC,GBA2,GBP5,GCAT,GCGR,GCSH,GDA,GDI2,GEN1,GFRA2,GGT1,GLA,GLS,GLS2,GMIP,GNA12,GNA14,GNGT1,GNL2,GNPDA2,GPC1,GPSM1,GPX3,GSK3B,GTF2H2,GTF2H3,GTPBP10,HACD3,HDAC6,HDC,HELB,HEXB,HLTF,HMMR,HNRNPU,HPRT1,HSD17B4,HSD17B6,HSP90B1,HSPA8,HSPD1,HSPH1,HTR2B,HYAL1,HYAL3,IAH1,IDO1,IL1B,IL2RA,INO80,INPP1,INPP5A,INPP5B,ITGA6,ITGB1BP1,ITSN2,JKAMP,KALRN,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LCMT1,LDAH,LIPJ,LLGL2,LONRF1,LPIN1,LTF,MADD,MAN2C1,MAP1LC3B,MAPK8,MCF2,MCF2L,METTL21A,MFN1,MMAA,MMP19,MNAT1,MRC2,MSTO1,MT-ATP6,MTG1,MTIF2,MTMR7,MTOR,MTRR,MUTYH,MYH10,MYH9,MYO10,MYO18A,MYO1B,NAGK,NAPEPLD,NCK1,NCOR1,NEU4,NF1,NOS3,NPLOC4,NPRL3,NSMCE2,NT5C2,NTRK2,NUDT9,OCRL,OGT,OPA1,P2RY12,PACS2,PAFAH1B1,PCBD1,PCYOX1,PDE1B,PDE2A,PDE4D,PDE5A,PDE6D,PDE8A,PDE9A,PDGFRB,PFKFB1,PFN2,PHKA1,PHYKPL,PICK1,PIK3C3,PIK3R2,PIN1,PKP4,PLA2G10,PLA2G4B,PLA2G4C,PLA2G5,PLBD1,PLCB1,PLCB2,PLCB4,PLCD3,PLCD4,PLCH1,PLD1,PLEKHG2,PLEKHG6,PLXNB1,PMS1,PMS2,POMT2,PON1,POR,PPP1CB,PREB,PRSS2,PSD3,PSD4,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD6,PSMG2,PTEN,PTK2,PTPRA,PXDN,QDPR,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB30,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RABL2A,RAC2,RACGAP1,RAD17,RAD18,RAD51C,RAD54B,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RBBP4,RECQL5,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOF,RHOT1,RIC1,RIC8B,RIMS1,RIT1,RNF121,RP2,RPGR,RRAGB,RRAS2,RUNDC1,RYR2,SBF1,SCOC,SEC61B,SEMA4D,SEPT4,SEPT5,SEPT9,SGPL1,SGSH,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT2,SIRT6,SLC25A17,SMARCA2,SMARCA5,SNAPIN,SNX14,SNX9,SOS1,SPATA13,SPATA18,SPG7,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TBL1XR1,TEX14,TGFB1,THY1,TIGAR,TLR9,TMED2,TMEM67 473.37 0.00071 0.0209673270440252 GO:0050790 regulation of catalytic activity biological_process 2295 508 ABCE1,ABI1,ABR,ACAP1,ACAP2,ACE,ACSL1,ADCY4,ADCYAP1,ADGRD1,ADNP,ADORA1,ADPRHL1,AGFG1,AHSA2,AIP,AKT1,AMBRA1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANKLE2,ANXA2,ANXA4,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARPP19,ATP1B1,ATP2B4,AURKB,AZIN2,BAG4,BAX,BCAS3,BCCIP,BCL2,BICD1,BIRC3,BIRC6,BIRC7,BMP2K,BNIP2,BOK,BRAF,BUB1B,C4A,C4B,CABIN1,CACUL1,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAND1,CARD16,CASP8,CCDC88A,CCL25,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCZ1,CD2BP2,CD44,CD74,CD81,CDC20B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDK12,CDK5RAP3,CDK7,CDKN3,CEP192,CFAP100,CFAP73,CFLAR,CHAD,CHN1,CHORDC1,CHRNA3,CHRNA7,CHTOP,CLN3,CNST,COL4A3,CR1,CRYAB,CSF1R,CSNK2A1,CSRNP3,CSTL1,CTC1,CUL1,CYTH4,DAB2IP,DAPK1,DBF4,DCUN1D4,DDR2,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DLG2,DLG3,DMPK,DNAJA1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF2AK2,EIF4A2,ELMOD3,ELP4,EPHA4,EPS8L1,ESR1,EZH2,FADD,FAF1,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FAS,FBXO7,FCER2,FGD3,FGD4,FGD6,FGF5,FGFR1,FGFR1OP,FNBP1,FNBP1L,FNTA,FRS2,FRY,FZR1,GABBR1,GADD45G,GBAS,GCGR,GCLM,GDI2,GEN1,GFRA2,GIPR,GLA,GMFB,GMFG,GMIP,GPC3,GPIHBP1,GPRC5B,GPSM1,GRHL2,GRM7,GSK3B,GSN,GSTP1,H2AFY,HACD3,HDAC6,HERC5,HGS,HIPK3,HMGN1,HNRNPU,HSP90B1,HSPD1,HSPH1,HTR2B,IGF1R,IL1B,IL2RA,INPP5B,IRAK1,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,KAT2B,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LCMT1,LIMK1,LLGL2,LRP6,LRRTM1,LRRTM3,LTF,LYPLA1,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MASTL,MCF2,MCF2L,MDM2,MEF2C,METTL21A,MID1IP1,MIDN,MNAT1,MPHOSPH10,MST1R,MTCH1,MTMR9,MTOR,MVP,NCK1,NDE1,NEK10,NEK7,NF1,NLRC5,NLRP12,NOS3,NOX4,NPM2,NPRL3,NRDC,NSMAF,NTRK2,NTRK3,NVL,OAZ1,OAZ2,OCRL,OGT,OPRM1,OSBPL8,OVOS2,P2RY12,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PAX2,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDE6D,PDGFRB,PDZD3,PFKFB1,PFN2,PIK3CA,PIK3CB,PIK3R2,PIK3R3,PIK3R5,PIN1,PKP4,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,PNKP,PODN,POR,POT1,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R3F,PPP1R42,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R3C,PPP2R5C,PPP2R5E,PPP4R1,PPP6R3,PREB,PRKAR2A,PRKCZ,PRLR,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRA,PTS,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RAC2,RACGAP1,RALB,RALGAPB,RANBP2,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RBL1,RELN,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,RIMS1,RNH1,ROBO1,RP2,RPGR,RPS2,RPS6KA1,RTN4RL2,RUNDC1,RYR2,SAE1,SASH1,SBF1,SEMA4D,SEPT2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SFTPB,SGK1,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SMYD3,SNX9,SORL1,SOS1,SPAG9,SPATA13,SPDYA,SPINT2,SPOCK3,SPRY1,SPTB,SPTBN1,SPTBN4,SSBP1,ST5,SUMO1,SYTL2,SZT2,TAB2,TAB3,TANK,TARBP2,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TCP1,TEFM,TELO2,TEX14,TFPI,TGFA,TGFB1,TGFBR1,THY1,TLR9,TMBIM6,TMED2,TNFRSF10B,TNK2,TNKS,TNNI3,TNNT2,TOM1L1,TOR1AIP1,TOR1AIP2,TP63,TRADD,TRAF4,TRIO,TRIP10,TSHR,TTK,UBA2,UBA52,UBE2E1,UCHL5,UGT1A1,USP6NL,UVRAG,VAV1,VEGFA,VIL1,WDR43 450.6 0.00072 0.021195987460815 GO:0043603 cellular amide metabolic process biological_process 896 214 ABCE1,ABTB1,ACACA,ACE,AEBP1,AGK,AGO1,AGO2,AKT1,ALDH1L1,ASAH1,ASNS,ASPG,ATF4,ATIC,ATXN2,BOLL,C12orf65,C1QBP,CAPRIN1,CARS,CDC123,CERS2,CHAC2,CLN3,CLN8,CNDP2,CNOT2,COA1,CPEB1,CPEB3,CPQ,CPS1,DALRD3,DAP3,DAPK1,DAPK3,DARS,DARS2,DDX1,DDX39B,DDX6,DEGS1,DHFR,DLD,DNAJC1,EEF1B2,EEF1D,EGFR,EIF1,EIF2A,EIF2AK2,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,EPRS,ERAP2,FTCD,FXR1,GALC,GARS,GART,GBA2,GCLC,GCLM,GGCT,GGH,GGT1,GIGYF2,GLA,GLRX2,GRB7,GSTA5,GSTM5,GSTP1,GTF2H2,GTF2H3,HAP1,HARS,HEXB,HNRNPD,HRASLS5,IGF2BP3,IMMP2L,IMPACT,ITGA2,ITGB8,LNPEP,LRPPRC,LTA4H,MALSU1,MAPKAPK5,MCTS1,METTL14,MKNK1,MME,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTG1,MTHFD1,MTHFD2L,MTIF2,MTIF3,MTOR,MTRF1,MTRF1L,MTRR,NARS,NCBP2,NDUFA7,NEU4,NGDN,NIT2,NSMAF,NSUN4,OGFOD1,ORMDL2,ORMDL3,PABPC1,PAIP2,PCSK5,PCSK7,PGLYRP2,PIWIL4,POLDIP3,POLR2G,PPP2R1A,PTCD3,PTK2B,PUM3,PURA,RARS,RARS2,RBM4,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RPS6KA1,RPS6KB1,RPS6KB2,RSL24D1,RXRA,SEC11C,SERP1,SGMS1,SGPL1,SHMT2,SLC25A32,SNU13,SPPL2A,ST3GAL3,ST3GAL5,ST3GAL6,TARBP2,THOP1,TIA1,TIGAR,TYMS,UBA52,UNK,WARS,WARS2,YAE1D1,YBX3,YRDC,ZC3H12A,ZNF385A,ZNF706 175.92 0.00073 0.02142321875 GO:1901800 positive regulation of proteasomal prote... biological_process 83 29 AKT1,ANKIB1,ARIH1,AURKA,CHFR,CLU,CUL3,DAB2IP,FBXO22,GCLC,GSK3B,MDM2,NSMCE2,NUB1,PIAS1,PLK3,PRICKLE1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RCHY1,RNF138,RNF14,RNF166,SIRT2,SUMO1,SUMO2 16.3 0.00077 0.0225266978193146 GO:1901070 guanosine-containing compound biosynthet... biological_process 18 10 GMPS,GUK1,HPRT1,IMPDH1,NME4,NME5,NME6,NME7,NME9,TYW5 3.53 0.00078 0.0227483850931677 GO:0031023 microtubule organizing center organizati... biological_process 118 38 AURKA,BCAS3,BRCA1,CENPJ,CEP135,CEP192,CEP63,CHD3,CHMP3,CHMP5,CHORDC1,CLASP1,CLASP2,DCTN1,FES,GCC2,GEN1,HAUS3,KIAA0753,MDM1,NDC1,NDE1,OFD1,PAFAH1B1,PCM1,PLK4,PPP1R12A,SASS6,SDCCAG8,SGO1,SSX2IP,TMEM67,TUBGCP5,USP33,UVRAG,WDR43,XPO1,XRCC3 23.17 0.00081 0.0235501857585139 GO:1903311 regulation of mRNA metabolic process biological_process 122 39 AGO2,BAG4,C1QBP,CCNT1,CDK11A,CNOT7,CNOT8,CPEB3,CTR9,CWC22,HNRNPA2B1,HNRNPK,HNRNPL,HSPA8,JMJD6,LEO1,NCBP2,PABPC1,PABPN1,PNPT1,POLR2G,PRR5L,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,SAP18,SLTM,SON,SREK1,SRPK2,SRSF7,THRAP3,TIA1,TRA2B,WTAP,ZC3H12A 23.95 0.00082 0.0237673456790123 GO:0051306 mitotic sister chromatid separation biological_process 47 19 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PPP2R1A,PSMG2,TEX14,TTK,XRCC3,ZNF207 9.23 0.00083 0.0239831692307692 GO:0031331 positive regulation of cellular cataboli... biological_process 302 82 AGO2,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ARIH1,AURKA,BUB1B,CALCOCO2,CDC23,CDC27,CDK5RAP3,CHFR,CLU,CNOT7,CNOT8,CPEB3,CUL1,CUL3,DAB2IP,EGF,FBXO22,FZR1,GCLC,GSK3B,IL1B,MDM2,MTDH,NRDC,NSMCE2,NUB1,PABPC1,PIAS1,PIK3CB,PLK3,PNPT1,POLR2G,PRICKLE1,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,RAB3GAP2,RALB,RCHY1,RNF138,RNF14,RNF166,SCOC,SIRT2,SNX9,SUMO1,SUMO2,TBC1D5,TFEB,UBA52,UBE2E1,UVRAG,WAC,ZC3H12A 59.29 0.00087 0.0250618711656442 GO:0071702 organic substance transport biological_process 2485 546 AAAS,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ACACA,ACAP1,ACE,ACSL1,ADA,ADCYAP1,ADIPOR2,ADORA1,ADPRHL1,AGFG1,AHCTF1,AIP,AKAP12,AKT1,AKTIP,ANK2,ANK3,ANO6,ANXA2,ANXA4,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APOO,APPL1,AQP7,AQP8,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGEF2,ARL2BP,ARL6,ARPP19,ASPSCR1,ATG16L2,ATG3,ATG4B,ATP11B,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP9B,ATXN2,AZIN2,BBS1,BBS2,BCAS3,BET1,BLK,BLZF1,BRAF,BTF3,BTK,C14orf166,C16orf62,C1QTNF5,C2CD5,C5AR2,CA1,CA12,CACNA1A,CACNA1C,CADPS2,CAMK2G,CCDC91,CD14,CD3G,CD74,CDC42,CDH1,CEP290,CEP57,CES1,CHD7,CHMP3,CHMP5,CHMP6,CHRNA3,CHRNA6,CHRNA7,CHTOP,CLEC4E,CLEC5A,CLN3,CLN8,CLTA,CLTC,CLU,CNST,COG2,COG5,COPA,COPB1,CORO7,CPT2,CRHBP,CROT,CRYM,CSE1L,CSF1R,CTDSPL2,CXCL12,CYLD,DAB2IP,DAG1,DDX39B,DENND1B,DENND4C,DMBT1,DNAJA1,DNAJC1,DNAJC13,DNM1L,DPH3,DSCR3,DUOXA1,DUSP16,DYRK2,ECT2,EGF,EGFR,EIF4E,ENY2,ERC1,EXOC1,EXOC4,EXOC6,EXOC6B,EXPH5,FABP5,FAF1,FAM21A,FBXO7,FBXW11,FIP1L1,FMN2,FRAS1,FYB,GBP5,GCC2,GDF9,GDI2,GET4,GGA1,GIF,GIPR,GJB1,GLS,GLS2,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPC3,GPIHBP1,GPR89B,GRB10,GRM7,GSK3B,GUK1,HAP1,HDAC1,HDAC6,HDLBP,HGS,HNRNPA2B1,HNRNPA3,HNRNPK,HOMER3,HOOK1,HSP90B1,HSPD1,HTR2B,ICA1,ICE1,IGF2BP3,IL1B,IL1R2,IL4R,IMMP2L,IPO11,IPO8,IPO9,ITGAV,ITGB1BP1,ITPR1,KANK1,KCNB1,KDELR2,KIF13A,KLHL20,LAMP2,LAMTOR1,LCN12,LCP1,LDLRAP1,LGR4,LITAF,LLGL2,LRAT,LRP6,LRPPRC,LYPLA1,LYST,M6PR,MAGOHB,MCFD2,MDM2,MFF,MFSD2A,MIA3,MIDN,MIP,MLPH,MON2,MTOR,MTTP,MTX1,MTX2,MTX3,MVP,MYH9,MYO18A,NAGPA,NAPB,NAPG,NASP,NCBP2,NCBP3,NCKIPSD,NCOA1,NCOA2,NCOR1,NDC1,NF1,NFE2L2,NISCH,NLRP12,NME4,NOP58,NOX5,NPLOC4,NRXN1,NTRK2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,OAZ1,OAZ2,OPRK1,OPRM1,OSBPL10,OSBPL1A,OSBPL2,OSBPL3,OSBPL5,OSBPL8,OSBPL9,P2RY12,PABPN1,PACS2,PAFAH1B1,PAN3,PARP10,PCK2,PCM1,PCSK5,PDE2A,PDZK1,PEX16,PEX3,PEX5L,PGAP1,PICK1,PIK3C3,PIK3R2,PIK3R3,PIP5K1A,PITPNB,PKDCC,PLA2G10,PLA2G5,PLEKHM1,PLK3,PLSCR4,PNPT1,POLA2,POLDIP3,PON1,POU2F2,PPFIA2,PPFIA4,PPM1B,PPY,PREB,PRELID3A,PRICKLE1,PRKCZ,PRR5L,PTPRN,PTTG1IP,RAB11FIP2,RAB18,RAB1A,RAB22A,RAB2A,RAB2B,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RAE1,RANBP2,RANBP3,RANBP6,RAP1A,RAPGEF4,RBCK1,RBMX2,RBPJ,RBPMS,RGPD1,RGPD5,RIMS1,RNPS1,RP2,RPGR,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RPS6KB1,RUFY3,RUNDC1,RXRA,SCAMP4,SCAMP5,SCFD1,SCFD2,SDAD1,SDCBP,SDCCAG3,SEC14L1,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SEH1L,SELENBP1,SENP2,SEPT2,SERINC3,SERP1,SGSM1,SGSM3,SHFM1,SIDT1,SIDT2,SIL1,SIRT6,SIX3,SLC11A2,SLC16A3,SLC16A4,SLC16A5,SLC16A7,SLC1A3,SLC1A7,SLC22A11,SLC22A2,SLC22A31,SLC22A7,SLC25A13,SLC25A17,SLC25A19,SLC25A27,SLC25A32,SLC25A36,SLC26A11,SLC28A2,SLC28A3,SLC2A11,SLC2A5,SLC2A9,SLC35A1,SLC35B1,SLC36A2,SLC38A2,SLC38A9,SLC44A4,SLC45A1,SLC4A2,SLC4A3,SLC51A,SLC5A1,SLC6A13,SLC6A19,SLC6A6,SLC7A11,SLC7A13,SLC7A2,SLC8B1,SLCO1A2,SMAD2,SMAD4,SMG1,SMG6,SNAP23,SNAP91,SNAPIN,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SORL1,SPNS3,SPRN,SPTBN1,SRI,SRP19,SRSF11,SRSF5,SRSF7,SSR1,SSR2,SSR3,STAM,STAR,STARD4,STARD7,STX5,STX8,STXBP2,STXBP4,SYT1,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TCP1,TF,TFR2,TFRC,TGFB1,TGFBR1,THOC1,THOC2,THOC7,TIMM10B 487.9 0.00089 0.0255596024464832 GO:0002223 stimulatory C-type lectin receptor signa... biological_process 103 34 CHUK,CLEC4E,CUL1,FBXW11,KRAS,MALT1,NRAS,PAK1,PAK2,PAK3,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,TAB2,TAB3,UBA52,UBE2V1 20.22 0.00091 0.0259751063829787 GO:0050684 regulation of mRNA processing biological_process 103 34 AGO2,C1QBP,CCNT1,CDK11A,CNOT7,CPEB3,CTR9,CWC22,HNRNPA2B1,HNRNPK,HNRNPL,HSPA8,JMJD6,LEO1,NCBP2,PABPC1,PABPN1,POLR2G,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,SAP18,SLTM,SON,SREK1,SRPK2,SRSF7,THRAP3,TIA1,TRA2B,WTAP 20.22 0.00091 0.0259751063829787 GO:0006310 DNA recombination biological_process 251 70 ACTL6A,AP5Z1,APEX2,ATRX,BRCA1,BRIP1,DMC1,DNA2,FIGNL1,GEN1,HELB,HSPD1,HUS1,INO80,INO80C,INO80D,INO80E,LIG3,LIG4,MCM8,MMS22L,MORF4L1,MSH5,NCOA6,NSMCE1,NSMCE2,NSMCE4A,NUCKS1,PARPBP,POLA1,POLA2,POLB,POLD3,POLD4,PPP4C,PRIM1,RAD51AP1,RAD51C,RAD52,RAD54B,RAD54L,RBBP8,RBPJ,RECQL5,RFC2,RFC4,RMI1,RNF138,RNF212,RNF8,RPA3,SFPQ,SHFM1,SIRT6,SMARCAD1,SMC6,STAT6,TCF7,TEX11,TFRC,TGFB1,THOC1,TOP2B,UBE2B,UCHL5,WHSC1,WRN,XRCC3,XRCC5,ZRANB3 49.28 0.00092 0.0261809696969697 GO:0007077 mitotic nuclear envelope disassembly biological_process 44 18 AAAS,CCNB2,CTDNEP1,LPIN1,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L 8.64 0.00096 0.0269920958083832 GO:0070925 organelle assembly biological_process 556 139 ABLIM3,ACTG1,ACTR2,AGFG1,AMBRA1,ANLN,ARL6,ARMC4,ATG16L2,ATG3,ATG4B,ATP6V0D1,ATXN10,ATXN2,AURKA,AURKB,BBS1,BBS2,BICD1,BIN2,BIRC3,BIRC7,BLK,BMS1,BRCA1,C1QBP,CCDC114,CENPA,CENPC,CENPJ,CEP135,CEP164,CEP192,CEP290,CEP63,CEP89,CFAP100,CFAP46,CFAP73,CFLAR,CHMP3,CHMP5,CHMP6,CLASP1,CNOT2,CNOT7,DDX6,DNAI1,DNAI2,DRC1,EDC3,EIF2A,EIF6,FAM161A,FAM175B,FARP2,FBF1,FHOD3,FNBP1L,FOXJ1,GRB7,GSN,HAUS3,HGS,HSPB11,INO80,IQCB1,IQCG,KIAA0753,KIF23,LCP1,LIMD1,LZTS2,MAP1LC3B,MAP9,MDM1,MEF2A,MEF2C,MKS1,MRPS11,MYH10,MYOZ3,NCOR1,NEK7,NME5,NPRL3,NSUN4,OCRL,OFD1,OGFOD1,ONECUT2,PACS2,PAFAH1B1,PAN3,PCM1,PDGFRB,PLK4,POC1B,PUM2,RAB1A,RAB3GAP2,RAB5A,RACGAP1,RALB,RFX2,RNF4,RPF1,RPF2,RPGR,RPL5,RPL6,RPS19,RPS5,RSL24D1,RSPH9,SASS6,SENP6,SEPT2,SPAG16,SSX2IP,STAM,TAPT1,TBPL1,TMEM175,TMEM237,TMEM67,TNKS,TPGS1,TRAPPC12,TRAPPC8,TUBB8,TUBGCP5,UBE2B,VPS36,VPS4A,VTA1,WDR45B,XIAP,ZNF207 109.16 0.00096 0.0269920958083832 GO:0042254 ribosome biogenesis biological_process 316 85 ABCE1,BMS1,C1D,C1QBP,CCDC59,CHD7,DCAF13,DDX47,DDX56,DIMT1,DROSHA,EIF2A,EIF6,ERI2,EXOSC8,FBL,GNL2,GTF2H5,GTPBP10,HEATR1,KRR1,LSM6,LTV1,MALSU1,METTL15,METTL16,MPHOSPH10,MRPL1,MRPS11,MTG1,NAT10,NGDN,NOL8,NOM1,NOP10,NOP2,NOP56,NOP58,NSA2,NSUN4,NVL,PTEN,RCL1,RIOK3,RPF1,RPF2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RRNAD1,RRP1,RRP36,RRP8,RSL24D1,SDAD1,SNU13,TFB1M,THUMPD1,UBA52,UTP11,UTP14A,UTP4,WDR12,WDR43,WDR75,XPO1,YAE1D1 62.04 0.00096 0.0269920958083832 GO:0003341 cilium movement biological_process 51 20 ADCY10,ARMC4,BBS2,CABYR,CCDC114,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,DNAH11,DNAI1,DNAI2,DPCD,HYDIN,NME5,OFD1,ROPN1L,RSPH9,SPAG16 10.01 0.00096 0.0269920958083832 GO:0016032 viral process biological_process 684 167 AAAS,ABCE1,ABI1,ACOT8,AP1G2,APOBEC3F,ATF7IP,BAX,BCL2,BICD1,BRD4,C14orf166,C1QBP,CALCOCO2,CASP8,CBX5,CCNT1,CCNT2,CD247,CD46,CD81,CDHR3,CDK13,CENPA,CENPU,CFLAR,CHD1,CHMP3,CHMP5,CHMP6,CLEC5A,COPB1,CR1,CTBP1,CUL1,CXADR,DAG1,DDB1,DDX39B,DDX6,DYNC1I2,DYNC1LI1,EIF2AK2,EIF4A1,EIF4A2,EIF4E,EIF4G3,EIF4H,FAM111A,FKBP6,FKBP8,GSN,GTF2B,HACD3,HDAC1,HMGA2,HNRNPK,HSPA8,HSPD1,ITGA2,ITGAV,ITGB6,KAT2B,KRT7,LIG4,LTF,MDM2,MFGE8,MPDZ,NDC1,NECTIN1,NEDD4L,NTRK3,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAAF1,PABPC1,PABPN1,PACS2,PAK2,PARP10,PCSK5,PDCL3,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,PSIP1,PSMA3,PSMA4,PSMB4,PSMB9,PSMC2,RAB1A,RAE1,RANBP2,RBCK1,RBL1,RNF216,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RTN3,RXRA,SEH1L,SF3B2,SNAPIN,SP1,SRPK2,SUMO1,SUPT4H1,TARBP2,TCEB1,TFRC,TGFB1,THOC1,THOC2,THOC7,TLN1,TNPO1,TRAM1,TRIM38,TRIM5,TSPAN7,TYMS,UBA52,UBE3A,UBR4,USP6NL,USP7,UVRAG,VPS4A,VTA1,WAPL,WWP1,XPO1,XRCC5,ZYX 134.3 0.00099 0.0277525074626866 GO:0016072 rRNA metabolic process biological_process 265 73 BMS1,C1D,CCDC59,CHD7,DCAF13,DDX47,DDX56,DIMT1,DROSHA,EIF6,ERI2,ERN2,EXOSC8,FBL,GTF2H5,HEATR1,KRR1,LSM6,LTV1,METTL15,METTL16,MPHOSPH10,MRPL1,MRPS11,NAT10,NGDN,NOL8,NOP10,NOP2,NOP56,NOP58,NSA2,NSUN4,RCL1,RIOK3,RPF1,RPF2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RRNAD1,RRP1,RRP36,RRP8,SNU13,TFB1M,THUMPD1,UBA52,UTP11,UTP14A,UTP4,WDR12,WDR43,WDR75,XRN1 52.03 0.00106 0.029626369047619 GO:0002478 antigen processing and presentation of e... biological_process 160 48 ABCB1,ABCB4,AP1G1,AP1M2,AP1S2,ARF1,CD74,CLTA,CLTC,CYBB,DCTN1,DCTN2,DCTN4,DCTN6,DYNC1I2,FCGR1B,HLA-DMB,HLA-DPB1,ITGAV,KIF15,KIF23,LNPEP,OSBPL1A,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RACGAP1,SEC24A,SEC24B,SEC24D,SEC31A 31.41 0.00107 0.0298171216617211 GO:0006362 transcription elongation from RNA polyme... biological_process 31 14 CDK7,GTF2H2,GTF2H3,GTF2H5,MNAT1,POLR1D,POLR2E,POLR2H,POLR2K,TAF1A,TAF1B,TAF1C,TAF1D,UBTF 6.09 0.00110 0.0304795614035088 GO:0090435 protein localization to nuclear envelope biological_process 8 6 ASUN,NUP155,NUP54,OSBPL8,SUMO1,TOR1AIP2 1.57 0.00111 0.0304795614035088 GO:0000082 G1/S transition of mitotic cell cycle biological_process 227 64 AKT1,AURKA,BAX,BCL2,BRD4,BRD7,CACUL1,CAMK2A,CAMK2G,CCNA1,CCNE2,CDC6,CDK7,CDKN3,CENPJ,CNOT2,CNOT7,CNOT8,CUL1,CUL3,CUL4B,DBF4,DHFR,E2F7,EGFR,EIF4E,EZH2,FBXO7,FHL1,GIGYF2,INO80,JADE1,KANK2,MCM2,MCM8,MDM2,MDM4,MNAT1,MTBP,MYO16,ORC4,PCBP4,PIAS1,PLCB1,PLK3,PLRG1,POLA1,POLA2,PRIM1,PRMT1,PSME3,PTEN,PTPN6,RBBP8,RFWD3,RPA3,RPS6KB1,SENP2,SPDYA,TP63,TYMS,UBA52,UBE2E2,ZNF385A 44.57 0.00111 0.0304795614035088 GO:0044843 cell cycle G1/S phase transition biological_process 227 64 AKT1,AURKA,BAX,BCL2,BRD4,BRD7,CACUL1,CAMK2A,CAMK2G,CCNA1,CCNE2,CDC6,CDK7,CDKN3,CENPJ,CNOT2,CNOT7,CNOT8,CUL1,CUL3,CUL4B,DBF4,DHFR,E2F7,EGFR,EIF4E,EZH2,FBXO7,FHL1,GIGYF2,INO80,JADE1,KANK2,MCM2,MCM8,MDM2,MDM4,MNAT1,MTBP,MYO16,ORC4,PCBP4,PIAS1,PLCB1,PLK3,PLRG1,POLA1,POLA2,PRIM1,PRMT1,PSME3,PTEN,PTPN6,RBBP8,RFWD3,RPA3,RPS6KB1,SENP2,SPDYA,TP63,TYMS,UBA52,UBE2E2,ZNF385A 44.57 0.00111 0.0304795614035088 GO:0051168 nuclear export biological_process 185 54 AAAS,ABCE1,AGFG1,CHTOP,CSE1L,CTDSPL2,DDX39B,DUSP16,EIF4E,EIF6,ENY2,FIP1L1,GSK3B,HNRNPA2B1,IL1B,LTV1,LZTS2,MALT1,MDM2,NCBP2,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,POLDIP3,RAE1,RANBP2,RANBP3,RBMX2,RNPS1,SDAD1,SEH1L,SHFM1,SMG1,SMG6,SRSF11,SRSF5,SRSF7,TGFB1,THOC1,THOC2,THOC7,XPO1,XPO7,XPOT 36.32 0.00111 0.0304795614035088 GO:0072657 protein localization to membrane biological_process 450 115 ADORA1,AKT1,ANK2,ANK3,ANXA2,APPL1,ARFRP1,ARHGEF16,ARL6,ATG3,ATG4B,ATP1B1,BAG4,BAX,BBS1,BBS2,BCL2,BLZF1,BRAF,C2CD5,CACNA1A,CACNB3,CASP8,CDH1,CLASP2,CNST,DENND4C,DLG2,DLG3,DPP10,EFR3A,EGFR,EHD2,EPB41L3,ETV5,FCHO2,FNTA,FYB,GAK,GCC2,GET4,GOLGA4,GOLGA7,HGS,ITGAL,ITGB1BP1,KCNB1,KCNIP4,KIF13A,LDLRAP1,LRP6,LYPLA1,MAPK8,MFF,NMT1,NRXN1,NUP155,NUP54,OSBPL8,PACS2,PDZK1,PEX16,PEX3,PICK1,PIGR,PIP5K1A,PKDCC,PKP2,PPIL2,PRKCZ,RAB3GAP2,RAB3IP,RAPGEF2,RAPSN,REEP1,RELN,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SCN3B,SDCBP,SEC63,SPTBN1,SPTBN4,SRP19,SSR1,SSR2,SSR3,SUMO1,SYTL2,TMED2,TP63,TRAM1,UBA52,VAMP4,VIL1,YWHAQ,YWHAZ 88.35 0.00112 0.0305753488372093 GO:0042590 antigen processing and presentation of e... biological_process 66 24 CYBB,FCGR1B,ITGAV,LNPEP,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4 12.96 0.00112 0.0305753488372093 GO:0006289 nucleotide-excision repair biological_process 116 37 AQR,ATXN3,CDK7,COPS2,COPS3,CUL4B,DDB1,GTF2H2,GTF2H3,GTF2H5,HMGN1,HUS1,LIG3,LIG4,MNAT1,PNKP,POLB,POLD3,POLD4,POLK,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,RAD52,RBBP8,RFC2,RFC4,RPA3,SLC30A9,SUMO1,SUMO2,UBA52,USP7,UVSSA 22.78 0.00114 0.0309414450867052 GO:0032200 telomere organization biological_process 116 37 ATR,ATRX,AURKB,CCT3,CCT7,CTC1,DNA2,DOT1L,HDAC8,HNRNPC,HNRNPU,MAP2K7,MAPKAPK5,NAT10,NEK7,NOP10,NSMCE2,PNKP,POLA1,POLA2,POLD3,POLD4,POT1,PRIM1,RAD51C,RFC2,RFC4,RPA3,SMC6,SMG1,SMG6,TCP1,TFIP11,TNKS,WRN,XRCC3,XRCC5 22.78 0.00114 0.0309414450867052 GO:0006405 RNA export from nucleus biological_process 120 38 AAAS,AGFG1,CHTOP,DDX39B,EIF4E,ENY2,FIP1L1,HNRNPA2B1,NCBP2,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,POLDIP3,RAE1,RANBP2,RBMX2,RNPS1,SEH1L,SHFM1,SMG1,SMG6,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7,XPOT 23.56 0.00115 0.0311229106628242 GO:0065009 regulation of molecular function biological_process 2761 601 ABCE1,ABI1,ABR,ACAP1,ACAP2,ACE,ACOD1,ACSL1,ADCY4,ADCYAP1,ADGRD1,ADNP,ADORA1,ADPRHL1,AGFG1,AHNAK,AHSA2,AIP,AKT1,AKTIP,AMBRA1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANK2,ANK3,ANKLE2,ANXA2,ANXA4,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARPP19,ATF2,ATP1B1,ATP2B4,AURKA,AURKB,AZIN2,BAG4,BAX,BCAS3,BCCIP,BCL2,BICD1,BIRC3,BIRC6,BIRC7,BMP2K,BNIP2,BOK,BRAF,BTK,BUB1B,BUD31,C3orf33,C4A,C4B,CABIN1,CACNA2D1,CACNB3,CACNB4,CACUL1,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAND1,CARD16,CASP8,CCDC88A,CCL25,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCZ1,CD2BP2,CD44,CD74,CD81,CDC20B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDK12,CDK5RAP3,CDK7,CDKN3,CDON,CEP192,CFAP100,CFAP73,CFLAR,CHAD,CHN1,CHORDC1,CHRNA3,CHRNA7,CHTOP,CHUK,CLN3,CLU,CNIH2,CNST,COL4A3,CPNE1,CR1,CRACR2A,CRBN,CRHBP,CRTAC1,CRYAB,CSF1R,CSNK2A1,CSRNP3,CSTL1,CTC1,CTTNBP2NL,CUL1,CYLD,CYTH4,DAB2IP,DAPK1,DBF4,DCUN1D4,DDR2,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DLG2,DLG3,DMPK,DNAJA1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,DOT1L,DPH3,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF2AK2,EIF4A2,ELMOD3,ELP4,EPHA4,EPS8L1,ERC1,ESR1,EZH2,FADD,FAF1,FAM13B,FAM150A,FAM58A,FANCA,FANCD2,FARP1,FARP2,FAS,FBXO7,FCER2,FGD3,FGD4,FGD6,FGF12,FGF5,FGFR1,FGFR1OP,FHL1,FNBP1,FNBP1L,FNTA,FOXJ1,FRS2,FRY,FXYD1,FZD6,FZR1,GABBR1,GADD45G,GBAS,GCGR,GCLM,GDI2,GEN1,GFRA2,GIPR,GLA,GMFB,GMFG,GMIP,GPC3,GPIHBP1,GPR35,GPRC5B,GPSM1,GRHL2,GRM7,GSK3B,GSN,GSTP1,H2AFY,HACD3,HAP1,HAVCR2,HDAC2,HDAC6,HERC5,HEYL,HGS,HIPK3,HMGA2,HMGN1,HNRNPU,HSP90B1,HSPD1,HSPH1,HTR2B,IGF1R,IL18BP,IL1B,IL2RA,INPP5B,IRAK1,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,KAT2B,KLHL24,KMT2A,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LCMT1,LDLRAP1,LFNG,LIMK1,LLGL2,LRP6,LRRTM1,LRRTM3,LTF,LYNX1,LYPLA1,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MASTL,MBTPS2,MCF2,MCF2L,MDM2,MED16,MEF2C,METTL21A,MFNG,MID1IP1,MIDN,MINK1,MITD1,MNAT1,MPHOSPH10,MST1R,MSX2,MTCH1,MTDH,MTMR9,MTOR,MVP,NCK1,NCOA2,NDE1,NEDD4L,NEK10,NEK7,NF1,NFKBID,NLGN3,NLRC5,NLRP12,NOS3,NOX4,NPM2,NPRL3,NRDC,NSMAF,NTRK2,NTRK3,NVL,OAZ1,OAZ2,OCRL,OGT,OPRM1,OSBPL8,OTULIN,OVOS2,P2RY12,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PARP10,PAX2,PAX7,PCBD1,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE4D,PDE5A,PDE6D,PDGFRB,PDZD3,PELI1,PFKFB1,PFN2,PIK3CA,PIK3CB,PIK3R2,PIK3R3,PIK3R5,PIN1,PKP4,PLA2G10,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,PLXND1,PNKP,PODN,PON1,POR,POT1,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R3F,PPP1R42,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R3C,PPP2R5C,PPP2R5E,PPP4R1,PPP6R3,PREB,PRKAR2A,PRKCZ,PRLR,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRA,PTS,PXDN,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RAC2,RACGAP1,RALB,RALGAPB,RANBP2,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RBCK1,RBL1,RELN,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,RIMS1,RNF2,RNF25,RNH1,ROBO1,RP2,RPGR,RPS2,RPS6KA1,RTN4RL2,RUNDC1,RYR2,SAE1,SASH1,SBF1,SCN3B,SEMA4D,SENP2,SEPT2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SFTPB 542.09 0.00118 0.0318430459770115 GO:0061640 cytoskeleton-dependent cytokinesis biological_process 38 16 ACTR2,ANK3,ANLN,AURKB,CENPA,FMN2,KIF23,MITD1,MYH10,NUSAP1,RACGAP1,SNX9,SON,SPTBN1,STAMBP,USP8 7.46 0.00125 0.0336353868194842 GO:0000724 double-strand break repair via homologou... biological_process 93 31 AP5Z1,BRCA1,DMC1,FIGNL1,GEN1,HELB,HUS1,INO80,LIG3,MCM8,MMS22L,MORF4L1,NSMCE1,NSMCE2,NUCKS1,PARPBP,PPP4C,RAD51AP1,RAD51C,RAD52,RAD54B,RAD54L,RBBP8,RECQL5,RNF138,RPA3,SFPQ,SHFM1,SIRT6,SMC6,XRCC3 18.26 0.00126 0.0338076 GO:0006302 double-strand break repair biological_process 186 54 AP5Z1,APBB1,ATP23,BRCA1,BRIP1,C9orf142,DDX1,DMC1,DNA2,EYA3,FIGNL1,GEN1,HELB,HMGA2,HUS1,INO80,LIG3,LIG4,MCM8,MMS22L,MORF4L1,MTA1,NSMCE1,NSMCE2,NUCKS1,PARPBP,POLA1,PPP4C,RAD51AP1,RAD51C,RAD52,RAD54B,RAD54L,RBBP8,RECQL5,RIF1,RNF138,RNF8,RPA3,SFPQ,SHFM1,SIRT6,SLF1,SMARCA5,SMARCAD1,SMC6,SUMO1,TDP1,TFIP11,TRIP12,WHSC1,WRN,XRCC3,XRCC5 36.52 0.00127 0.0338823011363636 GO:0015031 protein transport biological_process 1687 379 AAAS,ABAT,ACAP1,ADORA1,ADPRHL1,AHCTF1,AIP,AKAP12,AKT1,AKTIP,ANK2,ANK3,ANXA2,ANXA4,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGEF2,ARL2BP,ARL6,ASPSCR1,ATG16L2,ATG3,ATG4B,ATP6V0A4,ATP6V0D1,ATP6V1C2,BBS1,BBS2,BCAS3,BET1,BLK,BLZF1,BTF3,C16orf62,C1QTNF5,C2CD5,C5AR2,CACNA1A,CACNA1C,CADPS2,CAMK2G,CCDC91,CD14,CD3G,CD74,CDC42,CDH1,CEP290,CEP57,CHMP3,CHMP5,CHMP6,CLEC4E,CLEC5A,CLTA,CLTC,CLU,CNST,COG2,COG5,COPA,COPB1,CORO7,CSE1L,CSF1R,CTDSPL2,CYLD,DAB2IP,DAG1,DENND1B,DENND4C,DMBT1,DNAJA1,DNAJC1,DNAJC13,DNM1L,DPH3,DSCR3,DUOXA1,DUSP16,DYRK2,ECT2,EGF,EGFR,ENY2,ERC1,EXOC1,EXOC4,EXOC6,EXOC6B,EXPH5,FAF1,FAM21A,FBXO7,FBXW11,FMN2,FRAS1,FYB,GBP5,GCC2,GDI2,GET4,GGA1,GIPR,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPIHBP1,GPR89B,GSK3B,GUK1,HAP1,HDAC1,HDAC6,HGS,HOMER3,HOOK1,HSP90B1,HSPD1,HTR2B,ICA1,ICE1,IL1B,IL1R2,IL4R,IMMP2L,IPO11,IPO8,IPO9,ITGB1BP1,ITPR1,KANK1,KCNB1,KDELR2,KIF13A,KLHL20,LAMP2,LCP1,LGR4,LITAF,LLGL2,LYPLA1,LYST,M6PR,MCFD2,MDM2,MFF,MIA3,MIDN,MLPH,MON2,MTOR,MTX1,MTX2,MTX3,MVP,MYH9,MYO18A,NAGPA,NAPB,NAPG,NASP,NCKIPSD,NDC1,NF1,NLRP12,NOP58,NOX5,NPLOC4,NRXN1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OAZ1,OAZ2,OPRM1,PACS2,PAFAH1B1,PAN3,PARP10,PCK2,PCM1,PCSK5,PDE2A,PDZK1,PEX16,PEX3,PEX5L,PGAP1,PIK3C3,PIK3R2,PIP5K1A,PKDCC,PLEKHM1,PLK3,POLA2,POU2F2,PPM1B,PPY,PREB,PRICKLE1,PRKCZ,PRR5L,PTPRN,PTTG1IP,RAB11FIP2,RAB18,RAB1A,RAB22A,RAB2A,RAB2B,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RAE1,RANBP2,RANBP3,RANBP6,RAP1A,RAPGEF4,RBCK1,RBPJ,RBPMS,RGPD1,RGPD5,RIMS1,RP2,RPGR,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RUFY3,RUNDC1,SCAMP4,SCAMP5,SCFD1,SCFD2,SDAD1,SDCBP,SDCCAG3,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SEH1L,SELENBP1,SENP2,SERP1,SGSM1,SGSM3,SIDT2,SIL1,SIX3,SLC11A2,SLC8B1,SMAD2,SMAD4,SNAP23,SNAP91,SNAPIN,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SORL1,SPRN,SPTBN1,SRI,SRP19,SSR1,SSR2,SSR3,STAM,STX5,STX8,STXBP2,STXBP4,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TCP1,TF,TFR2,TFRC,TGFB1,TGFBR1,TIMM10B,TIMM23B,TIMM50,TLR1,TLR7,TLR9,TMBIM6,TMED2,TNKS,TNPO1,TOM1L1,TOMM20,TRAK1,TRAM1,TRAPPC8,TRIP6,UBA52,UEVLD,UNC93B1,USP6NL,UTS2,VAMP4,VPS11,VPS13A,VPS13B,VPS13C,VPS29,VPS36,VPS45,VPS4A,VPS54,VPS8,VTA1,VTCN1,WWTR1,XPO1,XPO7,XPOT,YKT6,YWHAQ,YWHAZ,ZC3H12A,ZDHHC17,ZFYVE16 331.22 0.00127 0.0338823011363636 GO:0007091 metaphase/anaphase transition of mitotic... biological_process 45 18 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PSMG2,TEX14,TTK,XRCC3,ZNF207 8.84 0.00130 0.0343895774647887 GO:0010965 regulation of mitotic sister chromatid s... biological_process 45 18 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PSMG2,TEX14,TTK,XRCC3,ZNF207 8.84 0.00130 0.0343895774647887 GO:0044784 metaphase/anaphase transition of cell cy... biological_process 45 18 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PSMG2,TEX14,TTK,XRCC3,ZNF207 8.84 0.00130 0.0343895774647887 GO:0002479 antigen processing and presentation of e... biological_process 63 23 CYBB,FCGR1B,ITGAV,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4 12.37 0.00132 0.0348205617977528 GO:0045185 maintenance of protein location biological_process 141 43 AKT1,ANK3,ARL2BP,AURKB,BICD1,CAMSAP3,CDC42,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,DAG1,DCTN1,ECT2,EPB41L3,FAF1,FAM175B,FBN1,FGFR1OP,GCC2,GET4,GSN,KDELR2,LTBP1,NLRP12,PCM1,RACGAP1,SEH1L,SGO1,SIRT2,SORL1,SPAG5,SPTBN4,SRI,SYNE1,TEX14,TLN1,TRIP6,TWF1,VPS13A,VPS13C,ZNF207 27.68 0.00133 0.0348883519553073 GO:0002220 innate immune response activating cell s... biological_process 105 34 CHUK,CLEC4E,CUL1,FBXW11,KRAS,MALT1,NRAS,PAK1,PAK2,PAK3,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,TAB2,TAB3,UBA52,UBE2V1 20.62 0.00133 0.0348883519553073 GO:0000723 telomere maintenance biological_process 113 36 ATR,ATRX,AURKB,CCT3,CCT7,CTC1,DNA2,HDAC8,HNRNPC,HNRNPU,MAP2K7,MAPKAPK5,NAT10,NEK7,NOP10,NSMCE2,PNKP,POLA1,POLA2,POLD3,POLD4,POT1,PRIM1,RAD51C,RFC2,RFC4,RPA3,SMC6,SMG1,SMG6,TCP1,TFIP11,TNKS,WRN,XRCC3,XRCC5 22.19 0.00136 0.0355759331476323 GO:0051252 regulation of RNA metabolic process biological_process 3646 780 ABCA2,ABCE1,ABLIM3,ACAD8,ACOD1,ACTL6A,ACTN1,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHNAK,AHR,AIP,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,APOBEC3F,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ARL2BP,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAG4,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLK2,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CWC22,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DROSHA,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,EIF4A2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FASTK,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FUS,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPH1,HNRNPK,HNRNPL,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBNL1,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUP107,NUP35,OGT,ONECUT2,OTULIN,PABPC1,PABPN1,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNPT1,PNRC2,POFUT1,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRR5L,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTBP2,PTEN,PTOV1,PTPRK,PTPRN,PURA,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM11,RBM25,RBM39,RBM4,RBM7,RBMX,RBPJ,RBPMS,RECQL5,RELN 715.85 0.00141 0.0367814166666667 GO:0043414 macromolecule methylation biological_process 272 74 ARID4A,ASH1L,ATF7IP,ATRX,BAZ2A,BRCA1,CHTOP,CMTR2,CTR9,DIMT1,DOT1L,EHMT1,EHMT2,EZH2,FBL,FBXO11,FKBP6,GATAD2A,GATAD2B,GRHL2,GSK3B,H2AFY,HELLS,KDM1B,KDM6A,KMT2A,KMT2D,KMT2E,LCMT1,MBD3,METTL1,METTL14,METTL15,METTL16,METTL21A,MTF2,MTO1,MTRR,MYB,NDUFAF7,NOP2,NSUN4,OGT,PAX7,PAXBP1,PCMT1,PCMTD1,PHF1,PICK1,PIK3CA,PIWIL4,PRDM16,PRMT1,PRMT3,PRMT5,PWP1,RLF,RRNAD1,SMAD4,SMYD2,SMYD3,TARBP1,TDRD5,TFB1M,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,USP7,WHSC1,WHSC1L1,WTAP 53.4 0.00142 0.0369396675900277 GO:0002758 innate immune response-activating signal... biological_process 242 67 ACOD1,BIRC3,BPIFB1,BTK,C1QBP,CASP8,CD14,CHUK,CLEC4E,CUL1,CYLD,DAB2IP,DMBT1,ESR1,FADD,FBXW11,HAVCR2,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LGR4,LTF,MALT1,NRAS,OTULIN,PAK1,PAK2,PAK3,PELI1,PGLYRP2,PIK3C3,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PUM2,SEC14L1,TAB2,TAB3,TANK,TBK1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,XIAP 47.51 0.00144 0.0373564640883978 GO:1903431 positive regulation of cell maturation biological_process 6 5 AURKA,BCL2,MTOR,OPA1,SIRT2 1.18 0.00146 0.0377709641873278 GO:0090168 Golgi reassembly biological_process 4 4 PDCD10,STK25,VCPIP1,YWHAZ 0.79 0.00148 0.0381831868131868 GO:0097659 nucleic acid-templated transcription biological_process 3648 780 ABCA2,ABLIM2,ABLIM3,ACAD8,ACOD1,ACTL6A,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ASH1L,ASUN,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CPSF3L,CRCP,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1,CSTF3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DRG1,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,EIF4A2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FIP1L1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF2BP,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,INTS10,INTS12,INTS6,INTS8,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LIN9,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUDT21,NUP107,NUP35,OGT,ONECUT2,OTULIN,PABPN1,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLDIP3,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R1B,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1,PTPRK,PTPRN,PURA,PWP1,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM39,RBMX,RBPJ,RBPMS,RECQL5,RELN,RFX2 716.25 0.00150 0.0384877049180328 GO:0044764 multi-organism cellular process biological_process 704 170 AAAS,ABCE1,ABI1,ACOT8,AP1G2,APOBEC3F,ATF7IP,BAX,BCL2,BICD1,BIRC3,BRD4,C14orf166,C1QBP,CALCOCO2,CASP8,CBX5,CCNT1,CCNT2,CD247,CD46,CD81,CDHR3,CDK13,CENPA,CENPU,CFLAR,CHD1,CHMP3,CHMP5,CHMP6,CLEC5A,COPB1,CR1,CTBP1,CUL1,CXADR,DAG1,DDB1,DDX39B,DDX6,DYNC1I2,DYNC1LI1,EIF2AK2,EIF4A1,EIF4A2,EIF4E,EIF4G3,EIF4H,FAM111A,FKBP6,FKBP8,GSN,GTF2B,HACD3,HDAC1,HMGA2,HNRNPK,HSPA8,HSPD1,ITGA2,ITGAV,ITGB6,KAT2B,KRT7,LIG4,LTF,MDM2,MFGE8,MPDZ,NDC1,NECTIN1,NEDD4L,NTRK3,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAAF1,PABPC1,PABPN1,PACS2,PAK2,PARP10,PCSK5,PDCL3,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,PSIP1,PSMA3,PSMA4,PSMB4,PSMB9,PSMC2,PUM2,RAB1A,RAE1,RANBP2,RBCK1,RBL1,RNF216,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RTN3,RXRA,SEC14L1,SEH1L,SF3B2,SNAPIN,SP1,SRPK2,SUMO1,SUPT4H1,TARBP2,TCEB1,TFRC,TGFB1,THOC1,THOC2,THOC7,TLN1,TNPO1,TRAM1,TRIM38,TRIM5,TSPAN7,TYMS,UBA52,UBE3A,UBR4,USP6NL,USP7,UVRAG,VPS4A,VTA1,WAPL,WWP1,XPO1,XRCC5,ZYX 138.22 0.00150 0.0384877049180328 GO:0009893 positive regulation of metabolic process biological_process 3510 752 ABAT,ABI1,ABLIM3,ABR,ACACA,ACAP1,ACAP2,ACE,ACOD1,ACSL1,ADCY4,ADCYAP1,ADGRD1,ADNP,ADORA1,ADPRHL1,AGFG1,AGO1,AGO2,AHR,AHSA2,AKAP12,AKNA,AKT1,AKTIP,ALOX15,AMBRA1,AMER1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD49,ANKRD6,ANXA2,APBB1,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ARID1B,ARID4A,ARIH1,ARL1,ARL2BP,ARPP19,ASH1L,ATAD1,ATF2,ATF4,ATF7IP,ATG4B,ATMIN,ATOH8,ATP1B1,ATP2B4,ATR,ATRX,ATXN7,AURKA,AURKB,AZIN2,BAG4,BANP,BAX,BCAS3,BCL2,BCLAF1,BIRC3,BIRC7,BMPR1B,BNIP2,BOK,BOLL,BPTF,BRAF,BRCA1,BRD4,BRD7,BTBD10,BTK,BUB1B,BUD31,C14orf166,C1QBP,C5AR2,CACUL1,CALCOCO2,CALM1,CAMK2A,CAMK2G,CAMTA1,CAND1,CARF,CASK,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CD44,CD46,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDK5RAP3,CDK7,CDON,CEP290,CFLAR,CHD1,CHD6,CHD7,CHFR,CHN1,CHRNA3,CHRNA7,CHTOP,CHUK,CLU,CNOT7,CNOT8,CNTN1,COL4A3,CPEB3,CR1,CREB5,CREM,CSF1R,CSNK2A1,CSNK2A3,CSRNP3,CTBP1,CTC1,CTDNEP1,CTR9,CUL1,CUL3,CUL4B,CYBB,CYTH4,DAB2IP,DAPK1,DBF4,DCAF6,DCUN1D4,DDR2,DDX39B,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DMRT2,DNA2,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,DOT1L,DROSHA,DUOXA1,DUSP9,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,ECT2,EGF,EGFR,EIF2A,EIF2AK2,EIF6,ELF1,ELF3,ELMOD3,EN1,ENPP2,ENY2,EPHA4,EPS8L1,ERC1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,EYA3,EYA4,EZH2,FADD,FAM13B,FAM150A,FAM58A,FANCI,FARP1,FARP2,FAS,FBXO22,FBXW11,FCER2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FNTA,FOXJ1,FOXN3,FOXN4,FRS2,FUBP1,FZR1,GABPB1,GADD45G,GCGR,GCLC,GCLM,GDF9,GDI2,GFRA2,GGA1,GIPR,GLI1,GMFB,GMFG,GMIP,GPBP1,GPBP1L1,GPC3,GPIHBP1,GPRC5B,GRHL1,GRHL2,GSK3B,GSN,GSTP1,GTF2B,H2AFY,HACD3,HAVCR2,HDAC1,HDAC2,HDAC6,HEATR1,HEXB,HEYL,HGS,HIVEP3,HLTF,HMGA2,HMGN1,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA7,HOXB1,HPRT1,HSF4,HSPA8,HSPD1,HSPH1,HTR2B,ICE1,ICE2,IGF1R,IL15,IL1B,IL2RA,IMPACT,INO80,INPP5B,IRAK1,IRF2,IRF5,ITGA2,ITGA6,ITGB1BP1,ITGB8,ITSN2,JADE1,JUND,KALRN,KAT2B,KAT6A,KDM6A,KDM7A,KLF6,KMT2A,KMT2D,KMT2E,KRAS,LAMTOR1,LAMTOR3,LAT,LDLRAP1,LEO1,LGR4,LIF,LLGL2,LMO2,LPIN1,LRP6,LTF,LYL1,MADD,MAFK,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MBTPS2,MCF2,MCF2L,MDM2,MED12L,MED13,MED14,MED16,MED21,MED24,MED30,MEF2A,MEF2C,MEIS2,MID1IP1,MINK1,MNAT1,MOB2,MOSPD1,MST1R,MTCH1,MTDH,MTF2,MTOR,MYB,MYF6,MYSM1,NAA16,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NEDD4L,NEK10,NEK7,NF1,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFYA,NIF3L1,NIPBL,NKD1,NLRC5,NLRP12,NOS3,NOX1,NOX4,NPAS3,NPM2,NPRL3,NR3C1,NRDC,NSMAF,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,NUCKS1,NVL,OAZ1,OAZ2,OCRL,OGT,OLFM1,OMA1,ONECUT2,OPRK1,OPRM1,OSBPL8,P2RY12,PABPC1,PAK1,PAK2,PAK3,PAWR,PAX2,PAX3,PAX7,PAXBP1,PBX1,PCBD1,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PELI1,PFKFB1,PFN2,PHF1,PHIP,PIAS1,PICK1,PIGA,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R5,PIN1,PKP4,PLA2G10,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLK3,PLXNB1,PNKP,PNPT1,POLDIP3,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POR,POT1,POU2F2,PPP1R12A,PPP1R12B,PPP1R7,PPP2R3C,PPP4R3B,PRDM16,PREB,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRR5L 689.15 0.00151 0.038638719346049 GO:0000725 recombinational repair biological_process 94 31 AP5Z1,BRCA1,DMC1,FIGNL1,GEN1,HELB,HUS1,INO80,LIG3,MCM8,MMS22L,MORF4L1,NSMCE1,NSMCE2,NUCKS1,PARPBP,PPP4C,RAD51AP1,RAD51C,RAD52,RAD54B,RAD54L,RBBP8,RECQL5,RNF138,RPA3,SFPQ,SHFM1,SIRT6,SMC6,XRCC3 18.46 0.00153 0.0390441032608696 GO:0043484 regulation of RNA splicing biological_process 98 32 AHNAK,C1QBP,CDK12,CLK2,CWC22,ESRP1,FASTK,HNRNPA2B1,HNRNPH1,HNRNPK,HNRNPL,HSPA8,JMJD6,MBNL1,PTBP2,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,SAP18,SON,SREK1,SRPK2,SRSF5,SRSF7,THRAP3,TIA1,TRA2B,WTAP,ZNF326 19.24 0.00156 0.0395944864864865 GO:0098781 ncRNA transcription biological_process 98 32 ASUN,CCNT1,CCNT2,CDK7,CPSF3L,ELL2,GTF2B,GTF3C2,GTF3C3,GTF3C5,H2AFY,ICE1,ICE2,INTS10,INTS12,INTS6,INTS8,MTOR,NCBP2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POU2F2,RPRD2,SNAPC3,SNAPC4,SP1,TAF1B,ZC3H8,ZNF143 19.24 0.00156 0.0395944864864865 GO:0010827 regulation of glucose transport biological_process 102 33 AAAS,ADIPOR2,AKT1,APPL1,ARPP19,ASPSCR1,C2CD5,GPC3,GRB10,IL1B,NDC1,NFE2L2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PIK3R2,PIK3R3,PRKCZ,RAE1,RANBP2,RAP1A,RPS6KB1,SEH1L,SIRT6,SLC25A27 20.03 0.00158 0.0398865053763441 GO:0032507 maintenance of protein location in cell biological_process 134 41 AKT1,ANK3,ARL2BP,AURKB,BICD1,CAMSAP3,CDC42,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,DAG1,DCTN1,ECT2,EPB41L3,FAF1,FAM175B,FGFR1OP,GCC2,GET4,GSN,KDELR2,NLRP12,PCM1,RACGAP1,SEH1L,SGO1,SIRT2,SORL1,SPAG5,SPTBN4,SRI,SYNE1,TEX14,TLN1,TRIP6,TWF1,VPS13A,VPS13C,ZNF207 26.31 0.00158 0.0398865053763441 GO:0001736 establishment of planar polarity biological_process 118 37 ANKRD6,CDC42,CELSR1,CELSR2,CLTC,DAAM1,DLG3,FZD6,GPC3,MKS1,NKD1,PAFAH1B1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SEC24B,TP63,UBA52,WNT11 23.17 0.00161 0.0404264973262032 GO:0007164 establishment of tissue polarity biological_process 118 37 ANKRD6,CDC42,CELSR1,CELSR2,CLTC,DAAM1,DLG3,FZD6,GPC3,MKS1,NKD1,PAFAH1B1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SEC24B,TP63,UBA52,WNT11 23.17 0.00161 0.0404264973262032 GO:0019884 antigen processing and presentation of e... biological_process 167 49 ABCB1,ABCB4,AP1G1,AP1M2,AP1S2,ARF1,CD1B,CD74,CLTA,CLTC,CYBB,DCTN1,DCTN2,DCTN4,DCTN6,DYNC1I2,FCGR1B,HLA-DMB,HLA-DPB1,ITGAV,KIF15,KIF23,LNPEP,OSBPL1A,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RACGAP1,SEC24A,SEC24B,SEC24D,SEC31A 32.79 0.00162 0.04056912 GO:0006351 transcription, DNA-templated biological_process 3646 779 ABCA2,ABLIM2,ABLIM3,ACAD8,ACOD1,ACTL6A,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ASH1L,ASUN,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CPSF3L,CRCP,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1,CSTF3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DRG1,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FIP1L1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF2BP,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,INTS10,INTS12,INTS6,INTS8,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LIN9,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUDT21,NUP107,NUP35,OGT,ONECUT2,OTULIN,PABPN1,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLDIP3,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R1B,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1,PTPRK,PTPRN,PURA,PWP1,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM39,RBMX,RBPJ,RBPMS,RECQL5,RELN,RFX2,RFX5 715.85 0.00164 0.0409607446808511 GO:0033121 regulation of purine nucleotide cataboli... biological_process 710 171 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AHSA2,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ATP1B1,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GSK3B,HACD3,HNRNPU,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MCF2,MCF2L,METTL21A,MTOR,NCK1,NF1,NPRL3,NTRK2,OCRL,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PFN2,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TLR9,TMED2,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,USP6NL,VAV1,WNT11 139.4 0.00165 0.0411011936339523 GO:0071985 multivesicular body sorting pathway biological_process 11 7 CHMP3,CHMP5,EXPH5,MITD1,RAB27B,UVRAG,VTA1 2.16 0.00175 0.0433621372031662 GO:0006312 mitotic recombination biological_process 46 18 DMC1,DNA2,GEN1,NSMCE2,POLA1,POLA2,POLD3,POLD4,PRIM1,RAD51C,RAD54B,RFC2,RFC4,RPA3,SMC6,TOP2B,WRN,XRCC3 9.03 0.00175 0.0433621372031662 GO:0000281 mitotic cytokinesis biological_process 29 13 ANK3,ANLN,CENPA,KIF23,MITD1,MYH10,NUSAP1,RACGAP1,SNX9,SON,SPTBN1,STAMBP,USP8 5.69 0.00179 0.0442365526315789 GO:0051304 chromosome separation biological_process 68 24 ANAPC10,ANAPC4,BUB1B,CDC23,CDC27,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PPP2R1A,PSMG2,RECQL5,SMARCAD1,SMC6,TEX11,TEX14,TOP2B,TTK,XRCC3,ZNF207 13.35 0.00180 0.0443669291338583 GO:0044033 multi-organism metabolic process biological_process 193 55 AAAS,APOBEC3F,CCNT1,CCNT2,CHD1,GTF2B,HDAC1,HMGA2,MAP2K3,MAP2K4,MAP2K7,NDC1,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,RAE1,RANBP2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SEH1L,SP1,SUPT4H1,TARBP2,UBA52 37.89 0.00183 0.0448708355091384 GO:0051169 nuclear transport biological_process 456 115 AAAS,ABCE1,AGFG1,AKT1,ANP32A,CDH1,CEP57,CHTOP,CSE1L,CTDSPL2,CYLD,DAB2IP,DAG1,DDX20,DDX39B,DUSP16,DYRK2,ECT2,EGF,EGFR,EIF4E,EIF6,ENY2,FAF1,FBXO22,FBXW11,FIP1L1,FYB,GSK3B,HNRNPA2B1,IL1B,IPO11,IPO8,IPO9,KANK1,LITAF,LTV1,LZTS2,MALT1,MDM2,MTOR,NCBP2,NCKIPSD,NDC1,NF1,NLRP12,NOP58,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,PARP10,PDE2A,PIK3R2,POLA2,POLDIP3,PPM1B,PPP1CC,PPP1R12A,PRICKLE1,PSIP1,PTTG1IP,RAE1,RANBP2,RANBP3,RANBP6,RBCK1,RBM4,RBMX2,RBPMS,RGS14,RNPS1,RPL23,RSRC1,SDAD1,SEC61B,SEH1L,SHFM1,SIX3,SMAD4,SMG1,SMG6,SNRPE,SNRPF,SPRN,SPTBN1,SRI,SRSF11,SRSF5,SRSF7,TBC1D10C,TBRG1,TGFB1,TGFBR1,THOC1,THOC2,THOC7,TLR7,TLR9,TNPO1,TRIP6,WRN,WWTR1,XPO1,XPO7,XPOT,ZC3H12A 89.53 0.00183 0.0448708355091384 GO:0009266 response to temperature stimulus biological_process 210 59 AAAS,ADORA1,AKT1,ARPP21,ATP2B1,ATR,ATXN3,BAG4,CAMK2A,CAMK2G,CASP8,CD14,CDH8,CHORDC1,CRYAB,CXCL12,DNAJA1,ERO1A,FKBP4,GCLC,GLRX2,GSK3B,HDAC2,HSPA8,HSPD1,HSPH1,HTR2B,IRAK1,MAP2K7,MKI67,MT-CO2,MTOR,NDC1,NF1,NOS3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PSIP1,RAE1,RANBP2,RBBP7,RPA3,RPS6KB1,SEH1L,SLC12A5,STAC,TFEC,TGFB1I1,TRPA1,TRPM3,YBX3 41.23 0.00185 0.0452430989583333 GO:0045184 establishment of protein localization biological_process 1827 406 AAAS,ABAT,ACAP1,ADORA1,ADPRHL1,AHCTF1,AIP,AKAP12,AKT1,AKTIP,ANK2,ANK3,ANXA2,ANXA4,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APPL1,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGEF16,ARHGEF2,ARL2BP,ARL6,ASPSCR1,ATG16L2,ATG3,ATG4B,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP9B,BAX,BBS1,BBS2,BCAS3,BCL2,BET1,BLK,BLZF1,BRAF,BTF3,C16orf62,C1QTNF5,C2CD5,C5AR2,CACNA1A,CACNA1C,CADPS2,CAMK2G,CASP8,CCDC91,CD14,CD3G,CD74,CDC42,CDH1,CEP290,CEP57,CHMP3,CHMP5,CHMP6,CLASP2,CLEC4E,CLEC5A,CLTA,CLTC,CLU,CNST,COG2,COG5,COPA,COPB1,CORO7,CSE1L,CSF1R,CTDSPL2,CYLD,DAB2IP,DAG1,DENND1B,DENND4C,DMBT1,DNAJA1,DNAJC1,DNAJC13,DNM1L,DPH3,DPP10,DSCR3,DUOXA1,DUSP16,DYRK2,ECT2,EFR3A,EGF,EGFR,ENY2,ERC1,EXOC1,EXOC4,EXOC6,EXOC6B,EXPH5,FAF1,FAM21A,FBXO7,FBXW11,FMN2,FRAS1,FYB,GAK,GBP5,GCC2,GDI2,GET4,GGA1,GIPR,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPIHBP1,GPR89B,GSK3B,GUK1,H2AFY,HAP1,HDAC1,HDAC6,HGS,HOMER3,HOOK1,HSP90B1,HSPD1,HTR2B,ICA1,ICE1,IL1B,IL1R2,IL4R,IMMP2L,IPO11,IPO8,IPO9,ITGA2,ITGB1BP1,ITPR1,KANK1,KCNB1,KDELR2,KIF13A,KLHL20,LAMP2,LCP1,LDLRAP1,LGR4,LITAF,LLGL2,LYPLA1,LYST,M6PR,MAPK8,MCFD2,MDM2,MFF,MIA3,MIDN,MLPH,MON2,MTOR,MTX1,MTX2,MTX3,MVP,MYH9,MYO18A,NAGPA,NAPB,NAPG,NASP,NCKIPSD,NDC1,NF1,NLRP12,NMT1,NOP58,NOX5,NPLOC4,NRAS,NRXN1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OAZ1,OAZ2,OPRM1,PACS2,PAFAH1B1,PAN3,PARP10,PCK2,PCM1,PCSK5,PDE2A,PDZK1,PEX16,PEX3,PEX5L,PGAP1,PIK3C3,PIK3R2,PIP5K1A,PKDCC,PKP2,PLEKHM1,PLK3,POLA2,POT1,POU2F2,PPM1B,PPY,PREB,PRICKLE1,PRKCZ,PRR5L,PTPRN,PTTG1IP,RAB11FIP2,RAB18,RAB1A,RAB22A,RAB2A,RAB2B,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RAE1,RANBP2,RANBP3,RANBP6,RAP1A,RAPGEF4,RBCK1,RBPJ,RBPMS,REEP1,RGPD1,RGPD5,RIMS1,RP2,RPGR,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RUFY3,RUNDC1,RYR2,SCAMP4,SCAMP5,SCFD1,SCFD2,SDAD1,SDCBP,SDCCAG3,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SEH1L,SELENBP1,SENP2,SERP1,SGSM1,SGSM3,SIDT2,SIL1,SIX3,SLC11A2,SLC8B1,SMAD2,SMAD4,SMYD3,SNAP23,SNAP91,SNAPIN,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SORL1,SPRN,SPTBN1,SPTBN4,SRI,SRP19,SSR1,SSR2,SSR3,STAM,STX5,STX8,STXBP2,STXBP4,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TCP1,TF,TFR2,TFRC,TGFB1,TGFBR1,TIMM10B,TIMM23B,TIMM50,TLR1,TLR7,TLR9,TMBIM6,TMED2,TNKS,TNPO1,TOM1L1,TOMM20,TP63,TRAK1,TRAM1,TRAPPC8,TRIP6,UBA52,UEVLD,UNC93B1,USH2A,USP6NL,UTS2,VAMP4,VIL1,VPS11,VPS13A,VPS13B,VPS13C,VPS29,VPS36,VPS45,VPS4A,VPS54,VPS8,VTA1,VTCN1,WHSC1,WWTR1,XPO1,XPO7,XPOT,YKT6,YWHAQ,YWHAZ,ZC3H12A,ZDHHC17,ZFYVE16 358.71 0.00194 0.0473208831168831 GO:0006760 folic acid-containing compound metabolic... biological_process 26 12 ALDH1L1,ATIC,DHFR,FTCD,GART,GGH,MTHFD1,MTHFD2L,MTRR,SHMT2,SLC25A32,TYMS 5.1 0.00197 0.0479281606217617 GO:0042769 DNA damage response, detection of DNA da... biological_process 36 15 CUL4B,DDB1,DNAJA1,HMGA2,MRPS11,MRPS35,PNKP,POLD3,POLD4,RAD18,RFC2,RFC4,RPA3,UBA52,UBE2B 7.07 0.00200 0.0485322997416021 GO:0032990 cell part morphogenesis biological_process 792 188 ABI1,ABLIM3,ACTR2,ADNP,ANK3,APBB1,APBB2,ARHGAP4,ARHGEF1,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BAX,BBS1,BBS2,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAPRIN1,CCDC114,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CHL1,CHN1,CHRNA3,COBL,CRTAC1,CSF1R,CTNNA1,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DCC,DHFR,DICER1,DNAI1,DNAI2,DNM1L,DNM3,DOCK7,DRC1,EGFR,ENPP2,EPB41L3,EPHA4,EPHB2,ETV1,EVL,FAM161A,FARP1,FBF1,FEZ1,FEZ2,FMN1,FNBP1L,FOXJ1,GALNT11,GOLGA4,GORASP1,GPC1,GPM6A,GSK3B,GSN,HDAC6,HPRT1,HSPB11,IFRD1,IQCB1,IQCG,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP1S,MAP2,MAP6,MAPK8IP3,MEF2A,METRN,MFF,MINK1,MKS1,MYH10,NECTIN1,NLGN3,NME5,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,ONECUT2,PAFAH1B1,PAK1,PAK3,PAX2,PCM1,PLA2G10,PLXNA1,PLXNB1,PLXNC1,PLXND1,PNPT1,POC1B,PRRX1,PTEN,PTK2,PTPRA,RAB1A,RAPGEF2,RAPH1,RELN,RFX2,RGMA,RNF6,ROBO1,ROBO3,RPGR,RSPH9,RTN4,RTN4RL2,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SGK1,SHTN1,SKIL,SLC11A2,SMAD4,SNX2,SOS1,SPAG16,SPTB,SPTBN1,SPTBN4,SSBP1,SSX2IP,STK25,SZT2,TAPT1,THY1,TLR9,TMEM237,TMEM67,TOP2B,TPGS1,TROVE2,TTC21B,UBE2B,ULK2,USP33,USP9X,VEGFA,VIL1,WEE1,WWTR1,ZNF280D 155.5 0.00201 0.0486492525773196 GO:0048002 antigen processing and presentation of p... biological_process 177 51 ABCB1,ABCB4,ACE,AP1G1,AP1M2,AP1S2,ARF1,CD74,CLTA,CLTC,CYBB,DCTN1,DCTN2,DCTN4,DCTN6,DYNC1I2,ERAP2,FCGR1B,HLA-DMB,HLA-DPB1,ITGAV,KIF15,KIF23,LNPEP,MR1,OSBPL1A,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RACGAP1,SEC24A,SEC24B,SEC24D,SEC31A 34.75 0.00203 0.0490070179948586 GO:0030071 regulation of mitotic metaphase/anaphase... biological_process 43 17 ANAPC10,ANAPC4,BUB1B,CDC23,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PSMG2,TEX14,TTK,XRCC3,ZNF207 8.44 0.00205 0.0492367007672634 GO:1902099 regulation of metaphase/anaphase transit... biological_process 43 17 ANAPC10,ANAPC4,BUB1B,CDC23,CDC6,CSNK2A1,CSNK2A2,CUL3,DYNC1LI1,GEN1,LCMT1,NSMCE2,PSMG2,TEX14,TTK,XRCC3,ZNF207 8.44 0.00205 0.0492367007672634 GO:1901068 guanosine-containing compound metabolic ... biological_process 928 217 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPD3,AMPH,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ATL2,BCAS3,BMS1,BNIP2,CALM1,CAMK2A,CAMK2G,CASK,CCL25,CCZ1,CDC42,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DLG2,DLG3,DNM1L,DNM3,DOCK4,DOCK7,ECT2,EGF,EGFR,EIF2S3,EIF5B,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GBP5,GCGR,GDI2,GFRA2,GMIP,GMPS,GNA12,GNA14,GNGT1,GNL2,GPSM1,GSK3B,GTPBP10,GUK1,HACD3,HPRT1,HTR2B,IL2RA,IMPDH1,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,MFN1,MMAA,MSTO1,MTG1,MTIF2,MTOR,NCK1,NF1,NME4,NME5,NME6,NME7,NME9,NPRL3,NTRK2,OCRL,OPA1,P2RY12,PAFAH1B1,PDE6B,PDE6D,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB30,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RABL2A,RAC2,RACGAP1,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOF,RHOT1,RIC1,RIC8B,RIMS1,RIT1,RP2,RPGR,RRAGB,RRAS2,RUNDC1,SBF1,SEMA4D,SEPT4,SEPT5,SEPT9,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TMED2,TNK2,TRIO,TRIP10,TUBB8,TYW5,USP6NL,VAV1,WNT11 182.2 0.00208 0.0498297959183673 GO:2000310 regulation of N-methyl-D-aspartate selec... biological_process 14 8 CNIH2,CRHBP,DAPK1,MEF2C,NLGN3,OPRM1,PTK2B,RELN 2.75 0.00211 0.0502919035532995 GO:0016073 snRNA metabolic process biological_process 84 28 ASUN,CCNT1,CCNT2,CDK7,CPSF3L,ELL2,EXOSC8,GTF2B,ICE1,ICE2,INTS10,INTS12,INTS6,INTS8,NCBP2,NOP10,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POU2F2,RPRD2,SNAPC3,SNAPC4,SP1,ZC3H8,ZNF143 16.49 0.00211 0.0502919035532995 GO:0006518 peptide metabolic process biological_process 728 174 ABCE1,ABTB1,ACE,AEBP1,AGO1,AGO2,AKT1,ATF4,ATXN2,BOLL,C12orf65,C1QBP,CAPRIN1,CARS,CDC123,CHAC2,CNDP2,CNOT2,COA1,CPEB1,CPEB3,CPQ,DALRD3,DAP3,DAPK1,DAPK3,DARS,DARS2,DDX1,DDX39B,DDX6,DNAJC1,EEF1B2,EEF1D,EGFR,EIF1,EIF2A,EIF2AK2,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,EPRS,ERAP2,FXR1,GARS,GCLC,GCLM,GGCT,GGT1,GIGYF2,GLRX2,GRB7,GSTA5,GSTM5,GSTP1,GTF2H2,GTF2H3,HAP1,HARS,HNRNPD,IGF2BP3,IMMP2L,IMPACT,ITGA2,LNPEP,LRPPRC,LTA4H,MALSU1,MAPKAPK5,MCTS1,METTL14,MKNK1,MME,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTG1,MTIF2,MTIF3,MTOR,MTRF1,MTRF1L,NARS,NCBP2,NDUFA7,NGDN,NSUN4,OGFOD1,PABPC1,PAIP2,PCSK5,PCSK7,PGLYRP2,PIWIL4,POLDIP3,POLR2G,PTCD3,PTK2B,PUM3,PURA,RARS,RARS2,RBM4,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RPS6KA1,RPS6KB1,RPS6KB2,RSL24D1,RXRA,SEC11C,SERP1,SNU13,SPPL2A,TARBP2,THOP1,TIA1,TYMS,UBA52,UNK,WARS,WARS2,YAE1D1,YBX3,YRDC,ZC3H12A,ZNF385A,ZNF706 142.94 0.00214 0.0508778227848101 GO:0006301 postreplication repair biological_process 54 20 BRCA1,HLTF,NPLOC4,NSMCE1,POLD3,POLD4,POLI,POLK,RAD18,RCHY1,REV1,RFC2,RFC4,RPA3,SPRTN,UBA52,UBE2B,UBE2F,UBE2V1,WDR33 10.6 0.00219 0.0519350757575758 GO:0006364 rRNA processing biological_process 259 70 BMS1,C1D,CCDC59,CHD7,DCAF13,DDX47,DDX56,DIMT1,EIF6,ERI2,EXOSC8,FBL,GTF2H5,HEATR1,KRR1,LSM6,LTV1,METTL15,METTL16,MPHOSPH10,MRPL1,MRPS11,NAT10,NGDN,NOL8,NOP10,NOP2,NOP56,NOP58,NSA2,NSUN4,RCL1,RIOK3,RPF1,RPF2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RRNAD1,RRP1,RRP36,RRP8,SNU13,TFB1M,THUMPD1,UBA52,UTP11,UTP14A,UTP4,WDR12,WDR43,WDR75 50.85 0.00225 0.0532235516372796 GO:0000956 nuclear-transcribed mRNA catabolic proce... biological_process 199 56 AGO1,AGO2,CNOT2,CNOT7,CNOT8,CPEB3,CSDE1,DDX6,EDC3,EIF4A1,EIF4A2,EIF4B,EIF4E,EXOSC8,LSM5,LSM6,MAGOHB,NCBP2,NT5C3B,PABPC1,PAN3,PAPD4,PARN,PNRC2,POLR2G,PPP2R1A,PPP2R2A,PRPF18,RNPS1,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SMG1,SMG6,THRAP3,UBA52,XRN1,ZC3H12A,ZCCHC11 39.07 0.00228 0.053797688442211 GO:0000722 telomere maintenance via recombination biological_process 33 14 DNA2,NSMCE2,POLA1,POLA2,POLD3,POLD4,PRIM1,RAD51C,RFC2,RFC4,RPA3,SMC6,WRN,XRCC3 6.48 0.00229 0.0538982205513784 GO:0019083 viral transcription biological_process 178 51 AAAS,CCNT1,CCNT2,CHD1,GTF2B,HDAC1,HMGA2,NDC1,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,RAE1,RANBP2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SEH1L,SP1,SUPT4H1,TARBP2,UBA52 34.95 0.00231 0.054233025 GO:1901566 organonitrogen compound biosynthetic pro... biological_process 1318 299 ABAT,ABCE1,ABHD3,ABTB1,ACACA,ACAT1,ADA,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADK,ADNP,AGK,AGO1,AGO2,AK2,AKAP12,AKR1A1,AKT1,ALDH18A1,ALDH3A2,ALDH3B2,ALDH7A1,AMD1,AMPD3,APLP1,APRT,ASNS,ASPG,ATF4,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATXN2,AZIN2,BOLL,C12orf65,C1QBP,CALM1,CAPRIN1,CARS,CDC123,CECR1,CERS2,CHAC2,CHST1,CLN8,CLTC,CMPK1,CNDP2,CNOT2,COA1,COASY,CPEB1,CPEB3,CPOX,CPS1,DALRD3,DAP3,DAPK1,DAPK3,DARS,DARS2,DCTD,DDX1,DDX39B,DDX6,DEGS1,DHFR,DNAJC1,DTYMK,EEF1B2,EEF1D,EGF,EGFR,EIF1,EIF2A,EIF2AK2,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELOVL6,ELOVL7,ENOPH1,EPRS,ESD,FABP5,FLAD1,FXR1,GABBR1,GARS,GART,GBAS,GCLC,GCLM,GGCT,GGT1,GIGYF2,GIPR,GLS,GLS2,GMPS,GPC1,GPC3,GRB7,GRM7,GRM8,GSTM5,GSTP1,GTF2H2,GTF2H3,GUK1,HACD3,HAP1,HARS,HDC,HNRNPD,HPRT1,HS6ST2,HTR2B,HYAL1,IDO1,IGF2BP3,IL1B,IMPACT,IMPDH1,ITGA2,KDSR,LPIN1,LRPPRC,MALSU1,MAPKAPK5,MAT2A,MCTS1,METTL14,MKNK1,MMAA,MOCS1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MT-ATP6,MTG1,MTHFD1,MTHFD2L,MTIF2,MTIF3,MTOR,MTRF1,MTRF1L,MTRR,NADK,NADSYN1,NARS,NCBP2,NDUFA7,NF1,NFE2L1,NGDN,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NOS3,NSMAF,NSUN4,OAZ1,OAZ2,OGFOD1,OPRM1,ORMDL2,ORMDL3,PABPC1,PAIP2,PANK1,PANK3,PANK4,PCBD1,PCSK5,PCYT1A,PDCL3,PDE2A,PDGFRB,PDXK,PDZD3,PIWIL4,PLA2G5,PNMT,POLDIP3,POLR2G,PPCDC,PSAT1,PTCD3,PTDSS1,PTK2B,PTS,PUM3,PURA,PXYLP1,PYCR1,QDPR,QTRT1,RARS,RARS2,RBM4,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RPS6KA1,RPS6KB1,RPS6KB2,RSL24D1,RXRA,SERP1,SGMS1,SGPL1,SHMT2,SLC11A2,SLC1A3,SLC25A13,SLC44A4,SNU13,ST3GAL3,ST3GAL5,ST3GAL6,SURF1,TARBP2,TBPL1,TGFB1,TIA1,TK1,TSHR,TYMS,TYW5,UBA52,UGDH,UNK,UPRT,WARS,WARS2,YAE1D1,YBX3,YRDC,ZC3H12A,ZNF385A,ZNF706 258.78 0.00232 0.0542953598014888 GO:0070936 protein K48-linked ubiquitination biological_process 47 18 HACE1,KLHL3,MARCH6,NEDD4L,PELI1,RNF216,RNF4,RNF6,RNF8,TRIM38,TTC3,UBE2B,UBE2E1,UBE2E2,UBE2G1,UBE2G2,UBE2T,UBE3A 9.23 0.00233 0.0542953598014888 GO:0006401 RNA catabolic process biological_process 242 66 AGO1,AGO2,CNOT2,CNOT7,CNOT8,CPEB3,CSDE1,DDX6,DNA2,DROSHA,EDC3,EIF4A1,EIF4A2,EIF4B,EIF4E,ERN2,EXOSC8,HNRNPD,LRPPRC,LSM5,LSM6,MAGOHB,NCBP2,NT5C3B,PABPC1,PAN3,PAPD4,PARN,PNPT1,PNRC2,POLR2G,PPP1R8,PPP2R1A,PPP2R2A,PRPF18,PRR5L,RNASET2,RNH1,RNPS1,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SMG1,SMG6,THRAP3,UBA52,XRN1,ZC3H12A,ZCCHC11 47.51 0.00233 0.0542953598014888 GO:0038095 Fc-epsilon receptor signaling pathway biological_process 149 44 BTK,CALM1,CHUK,CUL1,FBXW11,KRAS,LAT,MALT1,MAP2K4,MAP2K7,MAPK8,NFATC1,NRAS,PAK1,PAK2,PIK3CA,PIK3CB,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SOS1,TAB2,TAB3,UBA52,UBE2V1,VAV1 29.25 0.00238 0.0553232178217822 GO:0030030 cell projection organization biological_process 1176 269 ABI1,ABLIM3,ACTR2,ADCYAP1,ADNP,AKT1,ANK3,ANO6,APBB1,APBB2,ARF1,ARHGAP4,ARHGEF1,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BAG4,BBS1,BBS2,BCAS3,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAMSAP3,CAPRIN1,CARMIL2,CCDC114,CCDC78,CCDC88A,CDC42,CDC42EP3,CDH1,CDH13,CDH23,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CHL1,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CRTAC1,CSF1R,CTNNA1,CUL3,CUL4B,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DCC,DDX56,DHFR,DICER1,DNAH9,DNAI1,DNAI2,DNM3,DOCK7,DRC1,E2F5,EGFR,ENPP2,EPB41L3,EPHA4,EPHB2,EPS8L1,ETV1,EVL,EZH2,FAM110C,FAM150A,FAM161A,FARP1,FBF1,FBXO7,FES,FEZ1,FEZ2,FGD3,FGD4,FGD6,FGFR1,FKBP4,FMN1,FNBP1L,FOXJ1,FRY,FRYL,GAK,GALNT11,GOLGA4,GORASP1,GPC1,GPM6A,GPRC5B,GSK3B,GSN,HAP1,HDAC2,HDAC6,HPRT1,HSPB11,IFRD1,IQCB1,IQCG,ITGA2,ITGA6,ITM2C,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP1S,MAP2,MAP6,MAPK8IP3,MCF2,MDM2,MEF2A,MEF2C,METRN,MINK1,MKS1,MOB2,MTOR,MYH10,MYH9,MYLK,MYO10,MYOC,NCK1,NCKIPSD,NECTIN1,NFE2L2,NLGN3,NME5,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,ONECUT2,OPA1,P2RY12,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PAX2,PCM1,PFN2,PICK1,PIP5K1A,PLA2G10,PLD1,PLXNA1,PLXNB1,PLXNC1,PLXND1,POC1B,PRMT1,PRRX1,PTEN,PTK2,PTK2B,PTPRA,PTPRK,RAB1A,RAB5A,RAC2,RAP1A,RAP1B,RAP1GAP2,RAPGEF2,RAPH1,RELN,RFX2,RGMA,RNF6,ROBO1,ROBO3,RPGR,RSPH9,RTN4,RTN4RL2,RUFY3,SDCBP,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SGK1,SH3YL1,SHTN1,SKIL,SLC11A2,SLC12A5,SMAD4,SNAPIN,SNX2,SOS1,SPAG16,SPATA13,SPTB,SPTBN1,SPTBN4,SSX2IP,STK25,STMN4,STRC,STRN,SZT2,TAPT1,TEKT4,TGFBR1,THY1,TLR9,TMEM237,TMEM67,TOP2B,TPGS1,TROVE2,TTC21B,TTYH1,UBA6,UBE2B,ULK2,USH1C,USP33,USP9X,VEGFA,VIL1,WEE1,WWTR1,ZNF280D 230.9 0.00239 0.0554184938271605 GO:0009314 response to radiation biological_process 419 106 AIPL1,AKT1,ANGPT2,ASIC2,ASNS,ATF4,ATR,AURKB,BAX,BCL2,BRAF,BRCA1,CACNA2D4,CALM1,CCDC66,CLK2,CNGA1,COPS3,CRYAB,CUL4B,CXCL12,DDB1,DMC1,ECT2,EEF1D,EGFR,EYA3,FANCD2,FBXL3,FIGNL1,FNTA,GNGT1,GTF2H2,GTF2H5,HMGA2,HMGCS1,HMGN1,HUS1,HYAL1,HYAL3,IMPACT,INO80,JUND,KMT2A,KRAS,KRT13,LIG4,MAP2K7,MAPK8,MDM2,MEIS2,METAP2,MME,MTA1,MTOR,N4BP1,NF1,NIPBL,NLGN3,NMT1,NOX4,NUCKS1,OPRK1,OPRM1,PBK,PDE1B,PDE6B,PIAS1,PLK3,PNKP,POLB,PPP1CB,PPP1CC,PPP1R1B,PTPRK,RAD18,RAD51AP1,RAD51C,RAD54L,RBM4,RDH13,REV1,RFWD3,RGS14,RHBDD1,RNF8,RRH,SLC1A3,SLC24A1,SMC1A,SPRTN,STAR,TANK,TGFB1,TIGAR,TLK2,TOPBP1,TP63,TROVE2,UBE2B,UVSSA,WRN,XRCC3,XRCC5,XRRA1,ZRANB3 82.27 0.00242 0.0559759113300493 GO:0048858 cell projection morphogenesis biological_process 772 183 ABI1,ABLIM3,ACTR2,ADNP,ANK3,APBB1,APBB2,ARHGAP4,ARHGEF1,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BBS1,BBS2,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAPRIN1,CCDC114,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CHL1,CHN1,CHRNA3,COBL,CRTAC1,CSF1R,CTNNA1,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DCC,DHFR,DICER1,DNAI1,DNAI2,DNM3,DOCK7,DRC1,EGFR,ENPP2,EPB41L3,EPHA4,EPHB2,ETV1,EVL,FAM161A,FARP1,FBF1,FEZ1,FEZ2,FMN1,FNBP1L,FOXJ1,GALNT11,GOLGA4,GORASP1,GPC1,GPM6A,GSK3B,GSN,HDAC6,HPRT1,HSPB11,IFRD1,IQCB1,IQCG,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP1S,MAP2,MAP6,MAPK8IP3,MEF2A,METRN,MINK1,MKS1,MYH10,NECTIN1,NLGN3,NME5,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,ONECUT2,PAFAH1B1,PAK1,PAK3,PAX2,PCM1,PLA2G10,PLXNA1,PLXNB1,PLXNC1,PLXND1,POC1B,PRRX1,PTEN,PTK2,PTPRA,RAB1A,RAPGEF2,RAPH1,RELN,RFX2,RGMA,RNF6,ROBO1,ROBO3,RPGR,RSPH9,RTN4,RTN4RL2,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SGK1,SHTN1,SKIL,SLC11A2,SMAD4,SNX2,SOS1,SPAG16,SPTB,SPTBN1,SPTBN4,SSX2IP,STK25,SZT2,TAPT1,THY1,TLR9,TMEM237,TMEM67,TOP2B,TPGS1,TROVE2,TTC21B,UBE2B,ULK2,USP33,USP9X,VEGFA,VIL1,WEE1,WWTR1,ZNF280D 151.57 0.00244 0.0562998525798526 GO:0007051 spindle organization biological_process 141 42 ANKRD53,ASUN,AURKA,AURKB,BIRC3,BIRC7,BORA,CEP192,CEP63,CHD3,CHMP3,CHMP5,CLASP1,CLASP2,CLTC,DCTN2,FAM175B,HAUS3,INO80,KIF23,KIZ,LZTS2,MAP9,MYH9,NCOR1,NEK7,OFD1,PPP2R1A,PRC1,RACGAP1,RGS14,RNF4,SENP6,SMC1A,SPAG5,TNKS,TTK,TUBB8,TUBGCP5,UVRAG,XIAP,ZNF207 27.68 0.00246 0.0566222058823529 GO:0051052 regulation of DNA metabolic process biological_process 344 89 AKT1,APBB1,APOBEC3F,ATR,ATRX,AURKB,BRCA1,CCDC88A,CCT3,CCT7,CDC42,CDC6,CTC1,DDX39B,DNA2,E2F7,EGFR,EHMT2,EYA3,EYA4,FIGNL1,GLI1,GRHL2,GSK3B,HDAC8,HELB,HMGA2,HNRNPC,HNRNPU,HUS1,IGF1R,INO80,KDM1B,LIG3,MAP2K4,MAP2K7,MAPKAPK5,MBD3,NAT10,NEK7,NOX4,NPM2,NUCKS1,NVL,PAK3,PARP10,PARPBP,PDGFRB,PIK3CA,PNKP,POT1,PPP2R1A,PPP4C,PRMT5,PTK2B,RAD17,RAD51AP1,RAD52,RBBP6,RFC2,RFC4,RGN,RIF1,RLF,RNF8,SENP2,SIRT6,SLF1,SMARCAD1,SMC1A,SMG6,STAT6,TCP1,TFIP11,TFRC,TGFB1,THOC1,TIGAR,TNKS,TOM1L1,TRIP12,TTF1,UBE2B,UBE2V1,WAPL,WHSC1,WIZ,ZNF91,ZRANB3 67.54 0.00262 0.0601575061124694 GO:0090175 regulation of establishment of planar po... biological_process 109 34 ANKRD6,CDC42,CELSR1,CELSR2,CLTC,DAAM1,FZD6,GPC3,MKS1,NKD1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SEC24B,UBA52,WNT11 21.4 0.00268 0.0613850731707317 GO:0032781 positive regulation of ATPase activity biological_process 37 15 AHSA2,ATP1B1,CHTOP,DNAJB11,DNAJC1,DNAJC10,DNAJC24,HNRNPU,PFN2,RGN,RYR2,SUMO1,TNNT2,TOR1AIP1,TOR1AIP2 7.26 0.00277 0.0631385194174757 GO:2000425 regulation of apoptotic cell clearance biological_process 9 6 ALOX15,C2,C4A,C4B,ITGAV,MFGE8 1.77 0.00277 0.0631385194174757 GO:0010638 positive regulation of organelle organiz... biological_process 475 118 ACTR2,ACTR3C,ALOX15,ANKRD53,ANXA2,ARF1,ARHGEF15,ARPC1A,ARPC1B,ATR,ATRX,AURKA,AURKB,BAG4,BAX,BBC3,BCAS3,BCL2,BOK,BRAF,BRCA1,BRD7,C1QBP,C2CD5,CALCOCO2,CASP8,CCT3,CCT7,CDC42EP3,CHTOP,CLASP1,CLIP1,CNOT2,CTBP1,CTR9,CUL3,CYFIP1,DCTN1,DNM1L,EGF,EVL,FES,FMN1,GMFB,GMFG,GSK3B,GSN,H2AFY,IL1B,ITGB1BP1,KMT2A,LCP1,LIF,LIG4,LIMK1,MAP2K7,MAPK8,MAPKAPK5,MARCH5,MFF,MIER1,MSX2,MTF2,MTOR,MYB,MYOC,NCK1,NEK7,NIPBL,NMT1,NOX4,NPM2,NSMCE2,NSUN4,NTRK3,NUSAP1,OGT,OPA1,PAK1,PAN3,PAX7,PAXBP1,PDCD5,PDGFRB,PFDN2,PFN2,PHF1,PHIP,PICK1,PLCB1,PLK4,PNKP,POT1,PTK2B,RAB3GAP2,RALB,SFPQ,SIRT2,SLAIN2,SLF1,SMAD4,SORBS3,SYNPO,SYNPO2,SYT1,TAPT1,TCP1,TGFA,TGFB1,TGFBR1,TNKS,TP63,UBE2B,VEGFA,VIL1,WNT11,YWHAQ,YWHAZ 93.26 0.00279 0.063440411622276 GO:0006913 nucleocytoplasmic transport biological_process 448 112 AAAS,ABCE1,AGFG1,AKT1,ANP32A,CDH1,CEP57,CHTOP,CSE1L,CTDSPL2,CYLD,DAB2IP,DAG1,DDX20,DDX39B,DUSP16,DYRK2,ECT2,EGF,EGFR,EIF4E,EIF6,ENY2,FAF1,FBXO22,FBXW11,FIP1L1,FYB,GSK3B,HNRNPA2B1,IL1B,IPO11,IPO8,IPO9,KANK1,LITAF,LTV1,LZTS2,MALT1,MDM2,MTOR,NCBP2,NCKIPSD,NDC1,NF1,NLRP12,NOP58,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,NXF3,PABPN1,PARP10,PDE2A,PIK3R2,POLA2,POLDIP3,PPM1B,PPP1CC,PPP1R12A,PRICKLE1,PTTG1IP,RAE1,RANBP2,RANBP3,RANBP6,RBCK1,RBM4,RBMX2,RBPMS,RGS14,RNPS1,RPL23,RSRC1,SDAD1,SEC61B,SEH1L,SHFM1,SIX3,SMAD4,SMG1,SMG6,SNRPE,SNRPF,SPRN,SPTBN1,SRI,SRSF11,SRSF5,SRSF7,TBC1D10C,TGFB1,TGFBR1,THOC1,THOC2,THOC7,TLR7,TLR9,TNPO1,TRIP6,WWTR1,XPO1,XPO7,XPOT,ZC3H12A 87.96 0.00283 0.0641116346153846 GO:0006468 protein phosphorylation biological_process 1827 404 AAK1,AATK,ABI1,ABI3,ACE,ACSL1,ADAM10,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AKTIP,ALOX15,ALPK1,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARL2BP,ASH1L,ATP23,ATP2B4,ATR,AURKA,AURKB,BAG4,BAX,BCCIP,BCKDK,BCL2,BIRC6,BIRC7,BLK,BMP2K,BMPR1B,BRAF,BRD4,BTK,BUB1B,C3orf33,C5AR2,CACUL1,CALM1,CAMK2A,CAMK2G,CASK,CCDC88A,CCDC88C,CCL25,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD44,CD74,CD81,CDC42,CDC6,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CDON,CHAD,CHORDC1,CHRNA3,CHRNA7,CHUK,CLK2,CNTN1,CPNE3,CRYAB,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CTBP1,CUL1,CUL3,CUX1,DAB2IP,DAG1,DAPK1,DAPK3,DDR1,DDR2,DMPK,DNAJA1,DNAJC10,DOCK7,DOK4,DUSP16,DUSP9,DYRK2,DYRK4,ECT2,EGF,EGFR,EIF2A,EIF2AK2,ELP4,ENPP2,EPHA10,EPHA4,EPHB2,ERC1,ERN2,EZH2,FAF1,FAM150A,FAM58A,FAS,FASTK,FBXO7,FBXW11,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FRS2,FYB,GADD45G,GAK,GDF9,GFRA2,GMFB,GMFG,GPRC5B,GRK6,GSK3B,GSTP1,GTF2H2,GTF2H3,H2AFY,HACD3,HAVCR2,HDAC1,HDAC2,HERC5,HGS,HIPK3,HMGA2,HSPH1,HTR2B,HUS1,IGF1R,IGF2R,IL15,IL1B,IL22RA2,IL2RA,IMPACT,IRAK1,IRAK4,ITGAV,ITGB1BP1,KALRN,KAT2B,KRAS,KSR2,LAMTOR1,LAMTOR3,LAT,LIF,LIMK1,LMO3,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MARVELD3,MASTL,MEF2A,MEF2C,MELK,MINK1,MKNK1,MNAT1,MOB2,MST1R,MTOR,MVP,MYLK,MYO3B,MYOC,NCK1,NCOR1,NDRG2,NEK10,NEK11,NEK7,NF1,NLRP12,NOX1,NOX4,NRAS,NRP2,NTRK2,NTRK3,OPRK1,OPRM1,OSBPL8,PABPN1,PAFAH1B1,PAK1,PAK2,PAK3,PAN3,PAQR3,PBK,PDCD10,PDCL3,PDE4D,PDE5A,PDGFRB,PDIK1L,PDK3,PEAK1,PFN2,PHIP,PHKA1,PICK1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R5,PIN1,PKDCC,PLA2G5,PLCB1,PLK3,PLK4,PODN,PPP1R1B,PPP2R1A,PPP2R3C,PPP4C,PPP4R1,PRDX4,PRKAR2A,PRKCZ,PRLR,PRMT1,PRMT5,PRPF4B,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRA,RAC2,RALB,RAP1A,RAP1B,RAPGEF2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP4,RBM4,RBPMS,RELN,RELT,RGN,RGS14,RGS3,RIOK3,ROS1,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RPS6KC1,RPS6KL1,RSRC1,RTN4RL2,SASH1,SCYL2,SDCBP,SEMA4D,SEMA7A,SENP2,SGK1,SH2D3C,SHC2,SIRT2,SMAD2,SMAD4,SMAD9,SMG1,SMYD3,SNX9,SORBS3,SORL1,SOS1,SPAG9,SPDYA,SPEG,SPRY1,SPTB,SPTBN1,SPTBN4,SRPK2,SRPK3,STAP2,STK10,STK17A,STK25,STK32B,STRAP,TAB2,TAB3,TARBP2,TBC1D10C,TBCK,TBK1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TLK2,TLR7,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNK2,TNKS,TOM1L1,TRAF4,TRIM5,TRIO,TRPM6,TRPM7,TTK,TWF1,TYK2,UBA52,UBE2B,ULK2,USP15,UVRAG,VEGFA,WEE1,WNT11,WWTR1,ZAP70,ZC3H12A,ZMYM2,ZP4 358.71 0.00284 0.0641116346153846 GO:0051246 regulation of protein metabolic process biological_process 2459 534 ABI1,ABTB1,ACE,ACOT8,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AGO1,AGO2,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ANKLE2,ANKRD6,ANXA2,APBB1,ARHGAP8,ARHGEF2,ARIH1,ARL2BP,ARPP19,ASH1L,ATF4,ATG4B,ATP2B4,ATRX,ATXN2,AURKA,AZIN2,BAG4,BANP,BAX,BCCIP,BCL2,BIRC3,BIRC6,BIRC7,BOK,BOLL,BRAF,BRCA1,BRD4,BRD7,BTBD2,BTBD9,BUB1B,C12orf65,C1QBP,C2,C3orf33,C4A,C4B,C5AR2,CACUL1,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CCDC88A,CCDC88C,CCL25,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD44,CD46,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK12,CDK5RAP3,CDK7,CDKN3,CDON,CEP192,CHAD,CHFR,CHORDC1,CHRNA3,CHRNA7,CHTOP,CLN3,CLN8,CLU,CNOT2,CNST,CNTN1,COL4A3,CPEB1,CPEB3,CR1,CRYAB,CSF1R,CSNK2A1,CSNK2A2,CSNK2A3,CSRNP3,CSTL1,CTBP1,CTR9,CUL1,CUL3,CUL4B,CYBB,DAB2IP,DAG1,DAPK1,DAPK3,DCUN1D4,DDR2,DDX1,DDX39B,DDX6,DIABLO,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DOCK7,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELP4,ENPP2,EPHA4,EPRS,EZH2,FADD,FAF1,FAM150A,FAM58A,FANCI,FARP1,FAS,FBXO22,FBXO7,FBXW11,FGFR1,FGFR1OP,FMN2,FNTA,FOXJ1,FRS2,FXR1,FZR1,GADD45G,GCLC,GDF9,GEN1,GFRA2,GGA1,GIGYF2,GMFB,GMFG,GNA12,GPC3,GPRC5B,GRB7,GSAP,GSK3B,GSN,GSTP1,H2AFY,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC8,HERC5,HGS,HHATL,HIPK3,HNRNPD,HNRNPK,HSP90B1,HSPD1,HSPH1,HTR2B,HUS1,IGF1R,IGF2BP3,IL15,IL1B,IL1R2,IL22RA2,IMPACT,INPP5B,IRAK1,ITGA2,ITGAV,ITGB1BP1,ITM2C,KAT2B,KLHL40,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LCMT1,LDLRAD3,LIF,LIMK1,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALSU1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARVELD3,MASTL,MDM2,MDM4,MEF2C,METTL14,MINK1,MKNK1,MME,MNAT1,MOB2,MPHOSPH10,MST1R,MTCH1,MTF2,MTG1,MTIF2,MTOR,MTRF1,MVP,MYB,MYOC,N4BP1,NCBP2,NCK1,NCOR1,NDRG2,NEDD4L,NEK10,NF1,NGDN,NIPBL,NKD1,NLRP12,NMI,NOX1,NOX4,NRDC,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,OAZ1,OAZ2,OGFOD1,OGT,OPRK1,OPRM1,OSBPL8,OVOS2,PABPC1,PAFAH1B1,PAIP2,PAK1,PAK2,PAK3,PAQR3,PARP10,PAWR,PAX2,PAX7,PAXBP1,PBK,PCOLCE2,PDCD10,PDCD2,PDCD5,PDCL3,PDE4D,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PHIP,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PIWIL4,PLA2G10,PLA2G5,PLCB1,PLK3,PODN,POLDIP3,POLR2G,PON1,POR,PPP1R12A,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R3C,PPP2R5C,PPP2R5E,PPP6R3,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRMT3,PRMT5,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTCD3,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTTG1IP,PUM3,PURA,PXYLP1,RAC2,RALB,RAP1A,RAP1B,RAPGEF2,RBM4,RBPMS,RCHY1,RELN,RELT,RGN,RGS14,RGS3,RHBDD1,RNF138,RNF14,RNF166,RNF4,ROBO1,ROS1,RPS5,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RTN4RL2,RXRA,SASH1,SCAP,SDCBP,SEC24A,SEMA4D,SEMA7A,SENP2,SEPT4,SERP1,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SF3B3,SHC2,SIRT2,SMAD4,SMYD3,SNX9,SORBS3,SORL1,SPAG9,SPDYA,SPINT2,SPOCK3,SPRTN,SPRY1,SPTBN4,STAP2,STK25,STRAP,STX5,SUMO1,SUMO2,SUSD4,SYTL2,TAB2,TAB3,TANK,TARBP2,TBC1D10C,TBK1,TELO2,TEX14,TFPI,TGFA,TGFB1,TGFBR1,THY1,TIA1,TIPARP,TLK2,TLR1,TLR7,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNFSF12,TNK2,TOM1L1,TP63 482.8 0.00284 0.0641116346153846 GO:0070979 protein K11-linked ubiquitination biological_process 27 12 ANAPC10,ANAPC4,ANAPC5,ANAPC7,CDC23,CDC27,FZR1,RNF4,UBE2B,UBE2E2,UBE2T,UBE2W 5.3 0.00292 0.065759520383693 GO:0000075 cell cycle checkpoint biological_process 214 59 ATF2,ATR,AURKA,AURKB,BAX,BRCA1,BRIP1,BUB1B,CCNE2,CDC14B,CDC6,CDK5RAP3,CENPJ,CEP63,CHFR,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DDX39B,DNA2,DOT1L,DYNC1LI1,E2F7,FANCI,FOXN3,FZR1,GEN1,GIGYF2,HMGA2,HORMAD1,HUS1,KNTC1,LCMT1,MDM2,MDM4,NAE1,NEK11,PCBP4,PLK3,PRMT1,PSMG2,RAD17,RBBP8,RFWD3,SLF1,SMC1A,SPDL1,TEX14,TGFB1,THOC1,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 42.02 0.00295 0.0661180190930788 GO:0006402 mRNA catabolic process biological_process 214 59 AGO1,AGO2,CNOT2,CNOT7,CNOT8,CPEB3,CSDE1,DDX6,EDC3,EIF4A1,EIF4A2,EIF4B,EIF4E,EXOSC8,LSM5,LSM6,MAGOHB,NCBP2,NT5C3B,PABPC1,PAN3,PAPD4,PARN,PNPT1,PNRC2,POLR2G,PPP2R1A,PPP2R2A,PRPF18,PRR5L,RNH1,RNPS1,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SMG1,SMG6,THRAP3,UBA52,XRN1,ZC3H12A,ZCCHC11 42.02 0.00295 0.0661180190930788 GO:0019080 viral gene expression biological_process 180 51 AAAS,CCNT1,CCNT2,CHD1,GTF2B,HDAC1,HMGA2,NDC1,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,RAE1,RANBP2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SEH1L,SP1,SUPT4H1,TARBP2,UBA52 35.34 0.00298 0.066631380952381 GO:0030811 regulation of nucleotide catabolic proce... biological_process 743 176 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AHSA2,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ATP1B1,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,EIF6,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GSK3B,HACD3,HNRNPU,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MCF2,MCF2L,METTL21A,MTOR,NCK1,NCOR1,NF1,NPRL3,NTRK2,OCRL,OGT,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PFN2,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT6,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TIGAR,TLR9,TMED2,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,USP6NL,VAV1,WNT11 145.88 0.00302 0.0673653681710214 GO:0016575 histone deacetylation biological_process 82 27 ARID4A,BAZ2A,CHD3,CTBP1,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MORF4L1,MTA1,MTA3,NIPBL,PHF21A,RBBP4,RBBP7,SAP18,SFPQ,SIRT2,SIRT6,SMARCAD1,TBL1XR1,TGFB1,VEGFA 16.1 0.00305 0.0677128841607565 GO:0044728 DNA methylation or demethylation biological_process 82 27 ALKBH2,APOBEC3F,ATF7IP,ATRX,BAZ2A,BRCA1,EHMT1,EHMT2,EZH2,FKBP6,GATAD2A,GATAD2B,GRHL2,GSK3B,HELLS,KDM1B,KMT2A,KMT2E,MBD3,MTRR,PICK1,PIK3CA,PIWIL4,PRMT5,RLF,TDRD5,USP7 16.1 0.00305 0.0677128841607565 GO:0043254 regulation of protein complex assembly biological_process 377 96 ACTR2,ACTR3C,ALOX15,ANKRD53,ARF1,ARPC1A,ARPC1B,ATAT1,ATF7IP,BAG4,BAX,BCLAF1,BLK,CAND1,CAPZA1,CARMIL2,CDC42,CDC42EP3,CHMP3,CHMP5,CLASP1,CLDN7,CLIP1,CLU,CRBN,CUL4B,CYFIP1,DAB2IP,DCTN1,DDB1,DNM1L,EIF2AK2,EML2,EVL,FAF1,FARP2,FAS,FBLIM1,FCHSD1,FES,FHOD3,FKBP4,FMN1,GBP5,GMFB,GMFG,GSK3B,GSN,GTF2H2,GTF2H3,GTF2H5,HDAC6,HSPA8,ICE1,IMPACT,KANK1,LCMT1,LCP1,MTOR,NCK1,PAK3,PFN2,PICK1,PRKCZ,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTK2B,RALB,RNF4,RPA3,SEC24B,SENP6,SIRT2,SLAIN2,SLF1,SNX9,SORL1,SPTB,SPTBN1,SPTBN4,SUMO1,TBX20,TFIP11,TGFB1,TMC8,TRAPPC12,TRIOBP,TWF1,VEGFA,VIL1,VPS11,WNT10B,ZNF451 74.02 0.00307 0.0679961556603774 GO:0002218 activation of innate immune response biological_process 249 67 ACOD1,BIRC3,BPIFB1,BTK,C1QBP,CASP8,CD14,CHUK,CLEC4E,CUL1,CYLD,DAB2IP,DMBT1,ESR1,FADD,FBXW11,HAVCR2,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LGR4,LTF,MALT1,NRAS,OTULIN,PAK1,PAK2,PAK3,PELI1,PGLYRP2,PIK3C3,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PUM2,SEC14L1,TAB2,TAB3,TANK,TBK1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,XIAP 48.89 0.00310 0.0684990588235294 GO:0031124 mRNA 3-end processing biological_process 114 35 AGO2,CCNT1,CHTOP,CNOT2,CNOT7,CNOT8,CPEB3,CPSF6,CSTF1,CSTF3,CTR9,DDX39B,EIF4A1,EIF4A2,EIF4B,EIF4E,FIP1L1,LEO1,NCBP2,NUDT21,PABPC1,PABPN1,PAN3,PAPOLG,PARN,PNPT1,POLDIP3,POLR2G,RNPS1,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7 22.38 0.00314 0.0692200469483568 GO:0007030 Golgi organization biological_process 94 30 ARL1,ATL2,BCAS3,BLZF1,CDC42,CLASP1,CLASP2,COG2,GAK,GCC2,GORASP1,HACE1,KIFC3,MYO18A,NPLOC4,PDCD10,PLK3,PRMT5,RAB1A,RAB2A,RAB30,STK25,STX5,SYNE1,TMED2,UBXN2B,USP6NL,VAMP4,VCPIP1,YWHAZ 18.46 0.00317 0.0697177283372365 GO:0048024 regulation of mRNA splicing, via spliceo... biological_process 63 22 C1QBP,CWC22,HNRNPA2B1,HNRNPK,HNRNPL,HSPA8,JMJD6,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,SAP18,SON,SREK1,SRPK2,SRSF7,THRAP3,TIA1,TRA2B,WTAP 12.37 0.00319 0.0698305128205128 GO:0080135 regulation of cellular response to stres... biological_process 559 136 AAAS,AKT1,AMBRA1,ANKRD6,APBB1,ATP6V0D1,ATP6V1C2,ATR,BAG4,BAX,BCLAF1,BIRC7,BRAF,BRCA1,CALCOCO2,CAMK2A,CAMK2G,CD44,CD74,CDC42,CERS2,CHORDC1,CLN3,CRYAB,DAB2IP,DDX39B,DHFR,DNAJA1,EGFR,EIF2AK2,EPHA4,EXOC1,EXOC4,EYA3,EYA4,FBLN5,FIGNL1,FKBP4,FUT8,GADD45G,GSK3B,GSTP1,HACD3,HDAC6,HELB,HIPK3,HMGA2,HSPA8,HSPH1,IGF1R,IL1B,IMPACT,KLK8,KRAS,MAP2K4,MAP2K7,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MARVELD3,MDM2,MINK1,MTOR,NCOR1,NDC1,NFE2L2,NOX1,NPRL3,NSMCE1,NSMCE4A,NTRK3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OPRK1,PAFAH1B1,PAK1,PARPBP,PAWR,PBK,PDCD10,PLCB1,PNPT1,PPP4C,PRMT1,PRRX1,PTEN,PTK2B,PTTG1IP,RAB3GAP2,RAB5A,RAD51AP1,RAD52,RAE1,RALB,RANBP2,RFWD3,RGMA,RGN,RIF1,RNF8,RPA3,SASH1,SCOC,SDCBP,SEH1L,SENP2,SIRT6,SLF1,SMYD2,SPAG9,STK25,SZT2,TFIP11,THOC1,TIGAR,TLR9,TNFRSF19,TRAF4,TRIP12,UBE2V1,VEGFA,WAC,WHSC1,ZC3H12A,ZNF277 109.75 0.00319 0.0698305128205128 GO:0043001 Golgi to plasma membrane protein transpo... biological_process 34 14 ANK3,ARFRP1,BBS1,BBS2,BLZF1,CNST,GCC2,GOLGA4,GOLGA7,KIF13A,LYPLA1,PKDCC,SPTBN1,VAMP4 6.68 0.00320 0.069886511627907 GO:0080134 regulation of response to stress biological_process 1225 278 AAAS,ABAT,ABR,ACOD1,ADA,ADCYAP1,ADORA1,AKT1,AMBRA1,ANKRD6,ANO6,ANXA2,AP1G1,AP1M2,AP1S2,APBB1,APOBEC3F,ARF1,ASH1L,ASIC2,ATP6V0D1,ATP6V1C2,ATR,BAG4,BAX,BCLAF1,BIRC3,BIRC7,BPIFB1,BRAF,BRCA1,BRD4,BTK,C1QBP,C2,C4A,C4B,C5AR2,CALCOCO2,CAMK2A,CAMK2G,CASK,CASP4,CASP8,CD14,CD247,CD44,CD46,CD6,CD74,CDC42,CERS2,CHID1,CHORDC1,CHRNA7,CHUK,CLEC4E,CLN3,CR1,CRYAB,CUL1,CYLD,CYP19A1,DAB2IP,DDX39B,DHFR,DMBT1,DNAJA1,DROSHA,DUOXA1,EGFR,EIF2AK2,EPHA4,ESR1,EXOC1,EXOC4,EYA3,EYA4,FADD,FANCA,FANCD2,FBLN5,FBXW11,FIGNL1,FKBP4,FUT8,GADD45G,GBP5,GGT1,GPRC5B,GSK3B,GSTP1,HACD3,HAVCR2,HDAC6,HELB,HERC5,HIPK3,HMGA2,HSP90B1,HSPA8,HSPD1,HSPH1,IDO1,IGF1R,IL15,IL1B,IL1R2,IL22RA2,IL2RA,IMPACT,IRAK1,IRAK4,ITGA2,KANK1,KLK8,KRAS,LGR4,LTA,LTF,MALT1,MAP2K4,MAP2K7,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MARVELD3,MDM2,MEF2C,MINK1,MTA1,MTOR,MYLK,NCOR1,NCR1,NDC1,NFE2L2,NLRC5,NLRP12,NMI,NOS3,NOX1,NPRL3,NRAS,NSMCE1,NSMCE4A,NTRK3,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OPRK1,OSMR,OTULIN,PAFAH1B1,PAK1,PAK2,PAK3,PARPBP,PAWR,PBK,PCBP2,PDCD10,PDE2A,PELI1,PGLYRP2,PIAS1,PIK3C3,PLCB1,PNPT1,POLR3C,POLR3F,PPM1B,PPP4C,PRMT1,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2B,PTPN2,PTPN6,PTTG1IP,PUM2,RAB3GAP2,RAB5A,RAD51AP1,RAD52,RAE1,RALB,RANBP2,RFWD3,RGMA,RGN,RIF1,RNF216,RNF8,RPA3,RPS19,SASH1,SCOC,SDCBP,SEC14L1,SEH1L,SEMA7A,SENP2,SERPINB4,SESN1,SIRT2,SIRT6,SLC7A2,SLF1,SMYD2,SPAG9,STK25,SUMO1,SUSD4,SZT2,TAB2,TAB3,TANK,TARBP2,TBK1,TFIP11,TGFB1,THOC1,TIGAR,TLR1,TLR7,TLR9,TNFRSF19,TRAF4,TRIM38,TRIM5,TRIP12,TSPAN32,TSPAN8,TYK2,UBA52,UBE2V1,UNC93B1,VAV1,VEGFA,VIL1,WAC,WHSC1,XIAP,ZAP70,ZC3H12A,ZNF277,ZYX 240.52 0.00321 0.0699422505800464 GO:0051130 positive regulation of cellular componen... biological_process 1017 234 ABCB4,ABR,ACTR2,ACTR3C,ADCYAP1,ADNP,AKT1,ALOX15,ANK3,ANKRD53,ANO6,ANXA2,APBB1,ARF1,ARHGEF15,ARHGEF16,ARPC1A,ARPC1B,ASIC2,ATAD1,ATAT1,ATR,ATRX,AURKA,AURKB,BAG4,BAX,BBC3,BCAS3,BCL2,BCLAF1,BICD1,BOK,BRAF,BRCA1,BRD7,C1QBP,C2,C2CD5,C4A,C4B,CALCOCO2,CAND1,CAPRIN1,CARMIL2,CASP8,CCT3,CCT7,CD14,CDC42,CDC42EP3,CHTOP,CLASP1,CLASP2,CLIP1,CNOT2,CNST,CNTN1,COBL,CPEB3,CTBP1,CTR9,CUL3,CUL4B,CUX1,CXCL12,CYFIP1,DAB2IP,DCTN1,DDB1,DDR2,DDX56,DNM1L,DNM3,DPP10,EGF,EHD2,ENPP2,EPHA4,EPHB2,EPS8L1,EVL,EZH2,FAF1,FAM150A,FAS,FES,FEZ1,FGFR1,FMN1,FNBP1L,GBP5,GMFB,GMFG,GOLGA4,GPC3,GPM6A,GPRC5B,GSK3B,GSN,GTF2H2,GTF2H3,GTF2H5,H2AFY,HDAC2,HDAC6,HNRNPK,HYAL1,ICE1,IL1B,IL4R,ITGA2,ITGAV,ITGB1BP1,KALRN,KCNB1,KMT2A,LCP1,LDLRAP1,LIF,LIG4,LIMK1,LRRTM1,LRRTM3,MAP2K7,MAPK8,MAPKAPK5,MARCH5,METRN,MFF,MFGE8,MIER1,MOB2,MSX2,MTF2,MTOR,MYB,MYF6,MYOC,NCK1,NCKIPSD,NEDD4L,NEK7,NFE2L2,NIPBL,NLGN3,NMT1,NOX1,NOX4,NPM2,NRXN1,NSMCE2,NSUN4,NTRK2,NTRK3,NUSAP1,OGT,OLFM1,OPA1,PAFAH1B1,PAK1,PAK3,PAN3,PAX2,PAX7,PAXBP1,PDCD5,PDGFRB,PDZK1,PFDN2,PFN2,PHF1,PHIP,PICK1,PLCB1,PLK4,PLXNB1,PNKP,POT1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTK2B,RAB3GAP2,RAC2,RALB,RAP1A,RAPGEF2,RELN,ROBO1,RPA3,RUFY3,SCYL2,SDCBP,SEMA4D,SEMA7A,SFPQ,SGIP1,SHTN1,SIRT2,SKIL,SLAIN2,SLF1,SMAD2,SMAD4,SNX9,SORBS3,STK25,SUMO1,SYNPO,SYNPO2,SYT1,TAPT1,TBC1D5,TCP1,TF,TFR2,TGFA,TGFB1,TGFB1I1,TGFBR1,TNKS,TP63,TRIOBP,UBE2B,VEGFA,VIL1,WNT10B,WNT11,WWTR1,YWHAQ,YWHAZ 199.68 0.00334 0.0726063425925926 GO:0015937 coenzyme A biosynthetic process biological_process 12 7 ACACA,ACAT1,COASY,PANK1,PANK3,PANK4,PPCDC 2.36 0.00348 0.0753011059907834 GO:0070734 histone H3-K27 methylation biological_process 12 7 EHMT1,EHMT2,EZH2,H2AFY,MTF2,OGT,PHF1 2.36 0.00348 0.0753011059907834 GO:0051188 cofactor biosynthetic process biological_process 156 45 ACACA,ACAT1,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,ATIC,COASY,COQ4,CPOX,DHFR,DLAT,DLD,ELOVL6,ELOVL7,FLAD1,GART,HACD1,MAT2A,MOCS1,MTHFD1,MTHFD2L,NADK,NADSYN1,NDUFA9,NFE2L1,NMNAT3,NMRK1,PANK1,PANK3,PANK4,PCBD1,PDHB,PDK3,PDSS1,PDXK,PPCDC,PPT2,PTS,QDPR,SCD5,SLC11A2,TECR 30.63 0.00351 0.0756018577981651 GO:0070932 histone H3 deacetylation biological_process 21 10 HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,SFPQ,SIRT2,SIRT6,SMARCAD1 4.12 0.00351 0.0756018577981651 GO:0000154 rRNA modification biological_process 31 13 DIMT1,FBL,METTL15,METTL16,NAT10,NOP10,NOP2,NOP56,NOP58,NSUN4,RRNAD1,TFB1M,THUMPD1 6.09 0.00368 0.0787218223234624 GO:0033209 tumor necrosis factor-mediated signaling... biological_process 148 43 BAG4,BIRC3,CASP8,CHUK,CYLD,FAS,GSTP1,LTA,MADD,OTULIN,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTK2B,PTPN2,RBCK1,RELT,TAX1BP1,TNFRSF10B,TNFRSF13B,TNFRSF19,TNFRSF25,TNFSF12,TRADD,TXNDC17,UBA52 29.06 0.00368 0.0787218223234624 GO:0071897 DNA biosynthetic process biological_process 169 48 AURKB,BRCA1,BRIP1,CHRAC1,CTC1,DDX39B,DNA2,GRHL2,LIG3,LIG4,LIN9,MAP2K7,MAPKAPK5,NEK7,NOX4,NPLOC4,NVL,PAK3,PDGFRB,PNKP,POLA1,POLA2,POLB,POLD3,POLD4,POLI,POLK,POT1,PTK2B,RAD51AP1,RAD51C,RBBP8,RCHY1,REV1,RFC2,RFC4,RGN,RMI1,RPA3,SPRTN,TCP1,TK1,TNKS,TOM1L1,TYMS,UBA52,WRN,XRCC3 33.18 0.00368 0.0787218223234624 GO:0046112 nucleobase biosynthetic process biological_process 18 9 ADA,APRT,CECR1,CMPK1,CPS1,GART,GMPS,HPRT1,MTOR 3.53 0.00371 0.0790036507936508 GO:0046653 tetrahydrofolate metabolic process biological_process 18 9 ALDH1L1,ATIC,DHFR,FTCD,GART,MTHFD1,MTHFD2L,SHMT2,TYMS 3.53 0.00371 0.0790036507936508 GO:0006336 DNA replication-independent nucleosome a... biological_process 38 15 ATRX,CABIN1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,HAT1,ITGB3BP,MIS18BP1,NASP,RBBP4,RBBP7,SMARCA5 7.46 0.00375 0.0796747737556561 GO:0044403 symbiosis, encompassing mutualism throug... biological_process 719 170 AAAS,ABCE1,ABI1,ACOT8,AP1G2,APOBEC3F,ATF7IP,BAX,BCL2,BICD1,BRD4,C14orf166,C1QBP,CALCOCO2,CASP8,CBX5,CCNT1,CCNT2,CD247,CD46,CD81,CDHR3,CDK13,CENPA,CENPU,CFLAR,CHD1,CHMP3,CHMP5,CHMP6,CLEC5A,COPB1,CR1,CTBP1,CUL1,CXADR,DAG1,DDB1,DDX39B,DDX6,DYNC1I2,DYNC1LI1,EIF2AK2,EIF4A1,EIF4A2,EIF4E,EIF4G3,EIF4H,FAM111A,FKBP6,FKBP8,GSN,GTF2B,HACD3,HDAC1,HMGA2,HNRNPK,HSPA8,HSPD1,ITGA2,ITGAV,ITGB6,KAT2B,KRT7,LIG4,LTA,LTF,MDM2,MFGE8,MPDZ,NDC1,NECTIN1,NEDD4L,NTRK3,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAAF1,PABPC1,PABPN1,PACS2,PAK2,PARP10,PCSK5,PDCL3,PGLYRP2,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,PSIP1,PSMA3,PSMA4,PSMB4,PSMB9,PSMC2,RAB1A,RAE1,RANBP2,RBCK1,RBL1,RNF216,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RTN3,RXRA,SEH1L,SF3B2,SNAPIN,SP1,SRPK2,SUMO1,SUPT4H1,TARBP2,TCEB1,TCP1,TFRC,TGFB1,THOC1,THOC2,THOC7,TLN1,TNPO1,TRAM1,TRIM38,TRIM5,TSPAN7,TYMS,UBA52,UBE3A,UBR4,USP6NL,USP7,UVRAG,VPS4A,VTA1,WAPL,WWP1,XPO1,XRCC5,ZYX 141.17 0.00381 0.0805849324324324 GO:0044419 interspecies interaction between organis... biological_process 719 170 AAAS,ABCE1,ABI1,ACOT8,AP1G2,APOBEC3F,ATF7IP,BAX,BCL2,BICD1,BRD4,C14orf166,C1QBP,CALCOCO2,CASP8,CBX5,CCNT1,CCNT2,CD247,CD46,CD81,CDHR3,CDK13,CENPA,CENPU,CFLAR,CHD1,CHMP3,CHMP5,CHMP6,CLEC5A,COPB1,CR1,CTBP1,CUL1,CXADR,DAG1,DDB1,DDX39B,DDX6,DYNC1I2,DYNC1LI1,EIF2AK2,EIF4A1,EIF4A2,EIF4E,EIF4G3,EIF4H,FAM111A,FKBP6,FKBP8,GSN,GTF2B,HACD3,HDAC1,HMGA2,HNRNPK,HSPA8,HSPD1,ITGA2,ITGAV,ITGB6,KAT2B,KRT7,LIG4,LTA,LTF,MDM2,MFGE8,MPDZ,NDC1,NECTIN1,NEDD4L,NTRK3,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PAAF1,PABPC1,PABPN1,PACS2,PAK2,PARP10,PCSK5,PDCL3,PGLYRP2,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,PSIP1,PSMA3,PSMA4,PSMB4,PSMB9,PSMC2,RAB1A,RAE1,RANBP2,RBCK1,RBL1,RNF216,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RTN3,RXRA,SEH1L,SF3B2,SNAPIN,SP1,SRPK2,SUMO1,SUPT4H1,TARBP2,TCEB1,TCP1,TFRC,TGFB1,THOC1,THOC2,THOC7,TLN1,TNPO1,TRAM1,TRIM38,TRIM5,TSPAN7,TYMS,UBA52,UBE3A,UBR4,USP6NL,USP7,UVRAG,VPS4A,VTA1,WAPL,WWP1,XPO1,XRCC5,ZYX 141.17 0.00381 0.0805849324324324 GO:0006605 protein targeting biological_process 585 141 ADORA1,AIP,AKAP12,AKT1,ANK2,ANK3,ANXA2,AP1M2,ARL6,ATG3,ATG4B,C2CD5,CDH1,CEP57,CSE1L,CYLD,DAB2IP,DAG1,DYRK2,ECT2,EGF,EGFR,FAF1,FBXO7,FBXW11,FYB,GCC2,GNPTG,GOLGA4,GOLGA7,GSK3B,HGS,HOMER3,IL1B,IMMP2L,IPO11,IPO8,IPO9,ITGB1BP1,KANK1,KCNB1,LITAF,MFF,MTOR,MTX1,MTX2,MTX3,NAGPA,NCKIPSD,NF1,NLRP12,NOP58,NUP107,NUP155,NUP205,NUP35,NUP50,NUP54,NUP58,NUP98,PACS2,PAN3,PARP10,PDE2A,PDZK1,PEX16,PEX3,PEX5L,PIK3R2,PIP5K1A,POLA2,PPM1B,PRICKLE1,PTTG1IP,RAB3IP,RAE1,RANBP2,RANBP6,RBCK1,RBPMS,RGPD1,RGPD5,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SDCBP,SEC61B,SEC63,SIX3,SMAD4,SNX16,SORL1,SPRN,SPTBN1,SRI,SRP19,SSR1,SSR2,SSR3,STXBP4,TBC1D10C,TGFB1,TGFBR1,TIMM10B,TIMM23B,TIMM50,TLR7,TLR9,TMED2,TNPO1,TOMM20,TRAK1,TRAM1,TRAPPC8,TRIP6,UBA52,VPS13A,VPS13C,VPS36,WWTR1,YWHAQ,YWHAZ,ZC3H12A,ZFYVE16 114.86 0.00390 0.0823031460674157 GO:0043547 positive regulation of GTPase activity biological_process 599 144 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DOCK4,ECT2,EGF,EGFR,ELMOD3,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GSK3B,HACD3,HTR2B,IL2RA,INPP5B,ITGA6,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,NCK1,NF1,NPRL3,OCRL,P2RY12,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TRIO,TRIP10,USP6NL,VAV1,WNT11 117.61 0.00394 0.0829608520179372 GO:0016192 vesicle-mediated transport biological_process 1445 323 AAK1,ABI1,ABR,ACTG1,ACTN1,ACTR2,ADORA1,ADPRHL1,AKAP3,AKTIP,ALOX15,AMPH,ANK2,ANK3,ANO6,ANXA2,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,APLP1,ARF1,ARFGAP2,ARFRP1,ARL1,ARPC1A,ARPC1B,ATAD1,ATG3,ATL2,ATP9B,ATXN2,BBS1,BBS2,BCAS3,BET1,BICD1,BIN2,BLK,BLZF1,BRAF,BTBD9,BTK,C12orf4,C16orf62,C2,C2CD5,C3orf49,C4A,C4B,CACNA1A,CACNA1H,CADPS2,CALM1,CCZ1B,CD14,CD163,CD247,CD3G,CD6,CD81,CD9,CDC42,CDH13,CES1,CHMP3,CHMP5,CHRNA7,CLASP1,CLASP2,CLN3,CLTA,CLTC,CLU,CNIH1,CNIH2,CNST,COG2,COG5,COLEC11,COPA,COPB1,CORO7,CPLX2,CPNE1,CPNE3,CRHBP,CSNK1G1,CUL3,CUX1,CXCR2,CYFIP1,DCTN1,DCTN2,DCTN4,DCTN6,DENND1B,DMBT1,DNAJC13,DNM1L,DNM3,DYNC1I2,DYSF,EEA1,EGF,EHD2,ENPP2,EPG5,ERC1,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,EXPH5,FAM21A,FCGR1B,FCHO1,FCHO2,FES,FMN2,FNBP1,FNBP1L,GAK,GCC2,GCGR,GDI2,GGA1,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPC3,GPIHBP1,GSN,GTF2H2,HAP1,HMP19,HNRNPK,HOOK1,HSP90B1,HSPA8,HSPH1,HTR2B,IGF2R,IL1B,IL4R,ITGA2,ITGAL,ITGAV,ITSN2,JMJD6,KALRN,KCNB1,KDELR2,KIF13A,KIF15,KIF23,KLHL20,LAMP2,LAT,LDLRAD3,LDLRAP1,LIMK1,LLGL2,LMBR1L,LOXL4,LRP6,LRRTM1,LYPLA1,LYST,M6PR,MAL2,MAP4K2,MAPK8IP3,MCFD2,MEGF10,MFGE8,MFSD2A,MIA3,MITD1,MON2,MPPE1,MRC2,MYH10,MYH9,MYO10,MYO18A,MYO1B,MYO1G,NAPB,NAPG,NCK1,NCKIPSD,NEDD4L,NLGN3,OSBPL1A,OSBPL5,PAK1,PDLIM7,PEAR1,PECAM1,PFN2,PICK1,PIGR,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIP5K1A,PIP5K1C,PITPNB,PKDCC,PLCB1,PLCD4,PPP6R3,PREB,PSTPIP1,PTEN,PTK2,RAB11FIP2,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB5A,RABEP1,RABGAP1L,RAC2,RACGAP1,RALB,RAP1A,RAP1B,RAPGEF4,RGPD1,RGPD5,RIC1,RIMS1,RP2,RTN3,RUNDC1,SCAMP5,SCFD1,SCFD2,SCRN3,SCYL2,SDCBP,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEPP1,SEPT5,SERPINA3,SGIP1,SGSM1,SGSM3,SH3GL1,SNAP23,SNAP91,SNAPIN,SNX16,SNX19,SNX2,SNX4,SNX9,SORL1,SPAG9,SPTB,SPTBN1,SPTBN4,STX5,STX8,STXBP2,SYT1,SYT5,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TF,TFR2,TFRC,TGFA,TGFB1,TLN1,TMED2,TMEM175,TMX3,TNK2,TRAPPC12,TRAPPC2B,TRAPPC8,TRIP10,UBE3A,USP33,USP6NL,UVRAG,VAMP4,VAV1,VEGFA,VPS11,VPS13A,VPS13C,VPS29,VPS45,VPS4A,VPS54,VPS8,VTA1,YKT6,ZAP70,ZFYVE16,ZP4 283.71 0.00395 0.0829853467561521 GO:0034330 cell junction organization biological_process 234 63 ACTG1,ACTN1,ANK2,ARHGAP6,BCAS3,BCL2,CAMSAP3,CD9,CDC42,CDH1,CDH13,CDH8,CLASP1,CLASP2,COL17A1,CSF1R,CTNNA1,CTNND1,CXADR,DAPK3,DSG2,ECT2,EPB41L3,FBF1,FBLIM1,FMN1,FRMPD2,GJB1,GNPAT,GRHL2,HDAC7,ITGA2,ITGA6,ITGB1BP1,ITGB4,KIFC3,KRT5,LAMC2,LIMS2,MARVELD3,MTDH,MYOC,NECTIN1,PIP5K1A,PIP5K1C,PKP2,PKP4,PTEN,PTK2,PTK2B,PTPRK,RAP1A,RAP1B,RAPGEF2,RHOC,STRN,TGFB1,THY1,TLN1,TNS1,TRIP6,VEGFA,WNT11 45.94 0.00398 0.0834289732142857 GO:0009118 regulation of nucleoside metabolic proce... biological_process 748 176 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AHSA2,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ATP1B1,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,EIF6,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GSK3B,HACD3,HNRNPU,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MCF2,MCF2L,METTL21A,MTOR,NCK1,NCOR1,NF1,NPRL3,NTRK2,OCRL,OGT,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PFN2,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT6,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TIGAR,TLR9,TMED2,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,USP6NL,VAV1,WNT11 146.86 0.00404 0.0844980846325167 GO:0032436 positive regulation of proteasomal ubiqu... biological_process 68 23 AKT1,ANKIB1,ARIH1,AURKA,CHFR,CLU,CUL3,FBXO22,GCLC,GSK3B,MDM2,NSMCE2,NUB1,PIAS1,PLK3,PRICKLE1,RCHY1,RNF138,RNF14,RNF166,SIRT2,SUMO1,SUMO2 13.35 0.00412 0.0859798222222222 GO:0007093 mitotic cell cycle checkpoint biological_process 149 43 ATF2,AURKA,BAX,BUB1B,CDK5RAP3,CENPJ,CHFR,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DYNC1LI1,E2F7,FANCI,FOXN3,GEN1,GIGYF2,HMGA2,HUS1,KNTC1,LCMT1,MDM2,MDM4,NAE1,NEK11,PCBP4,PLK3,PRMT1,PSMG2,RAD17,RFWD3,SLF1,SMC1A,TEX14,TGFB1,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 29.25 0.00421 0.0876632150776053 GO:0043497 regulation of protein heterodimerization... biological_process 7 5 BAX,BCL2,CDC42,CDON,DAB2IP 1.37 0.00428 0.0887273289183223 GO:0097049 motor neuron apoptotic process biological_process 7 5 FADD,FAS,KCNB1,MAP2K4,MAP3K12 1.37 0.00428 0.0887273289183223 GO:0034329 cell junction assembly biological_process 183 51 ACTG1,ACTN1,ANK2,ARHGAP6,BCAS3,BCL2,CD9,CLASP1,CLASP2,COL17A1,CTNNA1,DAPK3,ECT2,EPB41L3,FBF1,FBLIM1,FMN1,FRMPD2,GJB1,GNPAT,GRHL2,HDAC7,ITGA2,ITGA6,ITGB1BP1,ITGB4,KRT5,LAMC2,LIMS2,MARVELD3,MTDH,MYOC,PIP5K1A,PIP5K1C,PKP2,PKP4,PTEN,PTK2,PTK2B,PTPRK,RAP1A,RAP1B,RAPGEF2,RHOC,STRN,THY1,TLN1,TNS1,TRIP6,VEGFA,WNT11 35.93 0.00430 0.0889455947136564 GO:0060071 Wnt signaling pathway, planar cell polar... biological_process 108 33 ANKRD6,CDC42,CELSR1,CELSR2,CLTC,DAAM1,FZD6,GPC3,MKS1,NKD1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,UBA52,WNT11 21.2 0.00440 0.0908140659340659 GO:0035601 protein deacylation biological_process 96 30 ARID4A,BAZ2A,CHD3,CTBP1,FNTA,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,LYPLA1,MAPK8,MBD3,MORF4L1,MTA1,MTA3,NIPBL,PHF21A,RBBP4,RBBP7,SAP18,SFPQ,SIRT2,SIRT5,SIRT6,SMARCAD1,TBL1XR1,TGFB1,VEGFA 18.85 0.00448 0.0918640305010893 GO:0098732 macromolecule deacylation biological_process 96 30 ARID4A,BAZ2A,CHD3,CTBP1,FNTA,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,LYPLA1,MAPK8,MBD3,MORF4L1,MTA1,MTA3,NIPBL,PHF21A,RBBP4,RBBP7,SAP18,SFPQ,SIRT2,SIRT5,SIRT6,SMARCAD1,TBL1XR1,TGFB1,VEGFA 18.85 0.00448 0.0918640305010893 GO:0006476 protein deacetylation biological_process 92 29 ARID4A,BAZ2A,CHD3,CTBP1,FNTA,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MORF4L1,MTA1,MTA3,NIPBL,PHF21A,RBBP4,RBBP7,SAP18,SFPQ,SIRT2,SIRT5,SIRT6,SMARCAD1,TBL1XR1,TGFB1,VEGFA 18.06 0.00449 0.0918640305010893 GO:0032465 regulation of cytokinesis biological_process 92 29 AKT1,AURKA,AURKB,BIRC6,CALM1,CCNC,CCNL2,CCNT1,CCNT2,CDC42,CDC6,CSPP1,CUL3,E2F7,ECT2,EGFR,FAM58A,KIF23,PIK3C3,PIN1,PKP4,PLK3,PRPF40A,RACGAP1,SDCCAG3,SPDYA,TEX14,UVRAG,VPS4A 18.06 0.00449 0.0918640305010893 GO:0031400 negative regulation of protein modificat... biological_process 615 147 AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ARPP19,ASH1L,BAG4,BAX,BRCA1,BUB1B,C3orf33,CALM1,CAMSAP3,CD2BP2,CDC23,CDC27,CDK5RAP3,CEP192,CHAD,CHORDC1,CNST,CSRNP3,CTBP1,DAB2IP,DAG1,DLG2,DLG3,DNAJA1,DNAJC10,DUSP16,DUSP9,DYNC1LI1,FARP1,FBXO7,FGFR1OP,FZR1,GCLC,GEN1,GFRA2,GMFB,GMFG,GSTP1,H2AFY,HDAC1,HDAC2,HDAC8,HHATL,HIPK3,IGF1R,IL1B,IMPACT,ITGB1BP1,KAT2B,KLHL40,LCMT1,LIF,LIMK1,LMO3,LRP6,LRRTM1,LRRTM3,MARVELD3,MASTL,MPHOSPH10,MTF2,MTOR,MVP,N4BP1,NCK1,NCOR1,NDRG2,NF1,NLRP12,NTRK3,OGT,PAFAH1B1,PAK2,PAQR3,PARP10,PBK,PDCL3,PDE4D,PHF1,PIN1,PODN,PPP1R1B,PPP2R1A,PRKAR2A,PRKCZ,PRMT3,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTEN,PTPN2,PTPN6,RGN,RGS14,RGS3,RNF4,RPS6KA6,RTN4RL2,SEMA4D,SENP2,SIRT2,SMAD4,SMYD3,SORL1,SPRY1,STRAP,SYTL2,TARBP2,TBC1D10C,TEX14,TGFB1,THY1,TRIP12,TTK,UBA52,UBE2B,UBE2E1,UFL1,USP4,WWTR1,XRCC3,ZC3H12A,ZNF207,ZNF451 120.75 0.00451 0.0920726304347826 GO:0044093 positive regulation of molecular functio... biological_process 1753 386 ABI1,ABR,ACAP1,ACAP2,ACE,ACSL1,ADCY4,ADCYAP1,ADGRD1,ADNP,ADORA1,ADPRHL1,AGFG1,AHSA2,AKT1,AKTIP,AMBRA1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANK2,ANK3,ANXA2,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ARL1,ATF2,ATP1B1,ATP2B4,AURKB,AZIN2,BAX,BCAS3,BCL2,BIRC7,BNIP2,BOK,BRAF,BTK,BUB1B,BUD31,CACNA2D1,CACUL1,CALM1,CAMK2A,CAMK2G,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCZ1,CD74,CD81,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CFLAR,CHN1,CHRNA3,CHRNA7,CHTOP,CHUK,CLU,COL4A3,CR1,CRACR2A,CRBN,CSF1R,CUL1,CYTH4,DAB2IP,DAPK1,DBF4,DCUN1D4,DDR2,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DPH3,DUSP9,ECT2,EGF,EGFR,EIF2AK2,ELMOD3,EPHA4,EPS8L1,ERC1,ESR1,EZH2,FADD,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FAS,FCER2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FNTA,FRS2,FZR1,GADD45G,GCGR,GCLM,GDI2,GFRA2,GIPR,GMFB,GMFG,GMIP,GPIHBP1,GPRC5B,GRHL2,GSK3B,GSN,HACD3,HAP1,HMGA2,HMGN1,HNRNPU,HSPD1,HSPH1,HTR2B,IGF1R,IL1B,IL2RA,INPP5B,IRAK1,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,KMT2A,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LFNG,LLGL2,LRP6,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MBTPS2,MCF2,MCF2L,MED16,MEF2C,MFNG,MID1IP1,MST1R,MTCH1,MTDH,NCK1,NCOA2,NEK10,NEK7,NF1,NLGN3,NLRP12,NOS3,NOX4,NPM2,NPRL3,NSMAF,NTRK3,NVL,OCRL,OGT,OSBPL8,P2RY12,PAK1,PAK2,PAK3,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PFKFB1,PFN2,PIK3CA,PIK3CB,PIK3R2,PIK3R5,PIN1,PKP4,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,PLXND1,PNKP,PON1,POR,POT1,PPP1R12A,PPP1R12B,PPP2R3C,PREB,PRKAR2A,PRKCZ,PRLR,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALB,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RBCK1,RELN,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,RNF25,ROBO1,RP2,RPGR,RPS2,RUNDC1,RYR2,SAE1,SASH1,SBF1,SEMA4D,SFTPB,SGK1,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT2,SNX9,SOS1,SPAG8,SPAG9,SPATA13,SPDYA,SPTB,SPTBN1,SPTBN4,SSBP1,ST5,STIM2,SUMO1,TAB2,TAB3,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TCP1,TELO2,TGFA,TGFB1,TGFBR1,THY1,TLR9,TNFRSF10B,TNKS,TNNT2,TOM1L1,TOR1AIP1,TOR1AIP2,TRADD,TRAF4,TRIM38,TRIM5,TRIO,TRIP10,TSHR,UBA2,UBA52,UBE2E1,UBE2V1,USP33,USP6NL,VAV1,VEGFA,WNT10B,WNT11,WRN,ZP4 344.18 0.00466 0.094928546637744 GO:0033044 regulation of chromosome organization biological_process 262 69 ANAPC10,ANAPC4,ATR,ATRX,AURKB,BRCA1,BRD7,BUB1B,CCT3,CCT7,CDC23,CDC27,CDC6,CHTOP,CSNK2A1,CSNK2A2,CTBP1,CTR9,CUL3,DYNC1LI1,GEN1,H2AFY,HDAC8,HNRNPC,HNRNPU,IL1B,KMT2A,LCMT1,LIF,LIG4,MAP1S,MAP2K7,MAPK8,MAPKAPK5,MIER1,MTF2,MYB,NAT10,NEK7,NIPBL,NSMCE2,OGT,PARP10,PAX7,PAXBP1,PHF1,PNKP,POT1,PSMG2,RNF4,SENP6,SFPQ,SLF1,SMAD4,SMG6,TCP1,TEX14,TGFB1,TLK2,TNKS,TRAPPC12,TRIP12,TTK,UBE2B,VEGFA,WAPL,XRCC3,ZNF207,ZNF451 51.44 0.00475 0.096541099137931 GO:0006471 protein ADP-ribosylation biological_process 25 11 ADNP,ART3,KAT2B,PARP10,PARP2,PUM3,SIRT2,SIRT5,SIRT6,TIPARP,TNKS 4.91 0.00476 0.096541099137931 GO:0046039 GTP metabolic process biological_process 906 209 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPD3,AMPH,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ATL2,BCAS3,BMS1,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DNM3,DOCK4,DOCK7,ECT2,EGF,EGFR,EIF2S3,EIF5B,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GBP5,GCGR,GDI2,GFRA2,GMIP,GNA12,GNA14,GNGT1,GNL2,GPSM1,GSK3B,GTPBP10,HACD3,HTR2B,IL2RA,IMPDH1,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,MFN1,MMAA,MSTO1,MTG1,MTIF2,MTOR,NCK1,NF1,NME4,NME5,NME6,NME7,NME9,NPRL3,NTRK2,OCRL,OPA1,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB30,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RABL2A,RAC2,RACGAP1,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOF,RHOT1,RIC1,RIC8B,RIMS1,RIT1,RP2,RPGR,RRAGB,RRAS2,RUNDC1,SBF1,SEMA4D,SEPT4,SEPT5,SEPT9,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TMED2,TNK2,TRIO,TRIP10,TUBB8,USP6NL,VAV1,WNT11 177.88 0.00477 0.096541099137931 GO:0034508 centromere complex assembly biological_process 39 15 CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,HELLS,ITGB3BP,MIS18BP1,RBBP4,RBBP7,RNF4,SENP6,SMARCA5,TRAPPC12 7.66 0.00501 0.100963326180258 GO:0034724 DNA replication-independent nucleosome o... biological_process 39 15 ATRX,CABIN1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,HAT1,ITGB3BP,MIS18BP1,NASP,RBBP4,RBBP7,SMARCA5 7.66 0.00501 0.100963326180258 GO:2001141 regulation of RNA biosynthetic process biological_process 3532 748 ABCA2,ABLIM3,ACAD8,ACOD1,ACTL6A,ACTN1,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ARL2BP,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,EIF4A2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FUS,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUP107,NUP35,OGT,ONECUT2,OTULIN,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1,PTPRK,PTPRN,PURA,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM39,RBMX,RBPJ,RBPMS,RECQL5,RELN,RFX2,RFX5,RFX7,RGMA,RGS14,RLF,RNF14,RNF2,RNF25,RNF4,RNF44,RNF6,RNF8,RORC,RPL6,RPS6KA1,RRP8,RUNX1T1,RXRA,RYR2,SAP18,SAP25 693.47 0.00512 0.102959143468951 GO:0045862 positive regulation of proteolysis biological_process 343 87 AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ARIH1,AURKA,BAX,BOK,BUB1B,CASP8,CDC23,CDC27,CDK5RAP3,CHFR,CLU,COL4A3,CR1,CUL1,CUL3,DAB2IP,DAPK1,DIABLO,EGF,FADD,FAS,FBXO22,FBXW11,FZR1,GCLC,GSK3B,GSN,HDAC2,HSPD1,IL1B,MDM2,MTCH1,NLRP12,NRDC,NSMCE2,NUB1,OGT,PCOLCE2,PDCD2,PDCD5,PIAS1,PLK3,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,RCHY1,RHBDD1,RNF138,RNF14,RNF166,ROBO1,SIRT2,SNX9,SUMO1,SUMO2,TANK,TNFRSF10B,TRADD,UBA52,UBE2E1 67.34 0.00520 0.104344444444444 GO:0071824 protein-DNA complex subunit organization biological_process 228 61 ANP32A,ARID2,ATF7IP,ATRX,BRD2,CABIN1,CAND1,CDK7,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CUL4B,DDB1,DMC1,GTF2H2,GTF2H3,GTF2H5,H2AFY,HAT1,HELLS,HIST1H2BN,ITGB3BP,KAT6A,MCM2,MIS18BP1,MNAT1,NAA60,NAP1L1,NAP1L4,NASP,PIAS1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSME4,RAD51C,RAD52,RBBP4,RBBP7,RNF4,RNF8,RPA3,SART3,SENP6,SMARCA5,SMARCD1,SMARCD2,SMARCE1,SMYD3,SYCP3,TAF1B,TAF2,TRAPPC12,UBA52,WNT10B,XRCC3 44.77 0.00527 0.105523603411514 GO:0006383 transcription from RNA polymerase III pr... biological_process 54 19 BRCA1,CRCP,GTF3C2,GTF3C3,GTF3C5,ICE1,ICE2,MTOR,POLR1D,POLR2E,POLR2H,POLR2K,POLR3C,POLR3F,SNAPC3,SNAPC4,TROVE2,ZC3H8,ZNF143 10.6 0.00538 0.107496978723404 GO:0050851 antigen receptor-mediated signaling path... biological_process 220 59 ADA,BCAR1,BCL2,BLK,BTK,CACNB3,CD247,CD3G,CD79B,CHUK,CUL1,DENND1B,ELF1,FBXW11,FYB,GCSAM,HLA-DPB1,LAT,MALT1,MEF2C,NCK1,PAK1,PAK2,PAK3,PAWR,PDE4D,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTPN2,PTPN6,RBCK1,TAB2,THY1,UBA52,UBE2V1,ZAP70 43.19 0.00567 0.113010338983051 GO:0007160 cell-matrix adhesion biological_process 194 53 ACTN1,ANGPTL3,ARHGAP6,BCAS3,BCL2,CASK,CCL25,CD44,CDH13,CLASP1,CLASP2,COL17A1,DAG1,DAPK3,DDR1,FBLN5,FMN1,GSK3B,HOXA7,ITGA2,ITGA6,ITGA7,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,JAM3,MINK1,MKLN1,MUC4,MYOC,NF1,ONECUT2,PARVG,PIK3CB,PIP5K1A,PPFIA2,PRKCZ,PTEN,PTK2,PTK2B,PTPRK,PXN,SNED1,STRC,THY1,TIMM10B,TRIP6,TRPM7,VEGFA,ZYX 38.09 0.00568 0.113010338983051 GO:1901407 regulation of phosphorylation of RNA pol... biological_process 10 6 BRD4,CCNC,CCNL2,CCNT1,CCNT2,FAM58A 1.96 0.00577 0.114230861344538 GO:2000765 regulation of cytoplasmic translation biological_process 10 6 CPEB1,CPEB3,HAP1,UNK,YBX3,ZNF385A 1.96 0.00577 0.114230861344538 GO:0031123 RNA 3-end processing biological_process 143 41 AGO2,CCNT1,CHTOP,CNOT2,CNOT7,CNOT8,CPEB3,CPSF6,CSTF1,CSTF3,CTR9,DDX39B,EIF4A1,EIF4A2,EIF4B,EIF4E,ELAC2,ERI2,EXOSC8,FBL,FIP1L1,LEO1,NCBP2,NUDT21,PABPC1,PABPN1,PAN3,PAPD4,PAPOLG,PARN,PNPT1,POLDIP3,POLR2G,RNPS1,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7,ZCCHC11 28.08 0.00578 0.114230861344538 GO:0090263 positive regulation of canonical Wnt sig... biological_process 118 35 AMER1,CTDNEP1,DAPK3,GPRC5B,LGR4,LGR5,LRP6,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RBPJ,RNF220,TNKS,UBA52,USP34,WNT10B,XIAP 23.17 0.00579 0.114230861344538 GO:2001021 negative regulation of response to DNA d... biological_process 29 12 CD44,CD74,DDX39B,HELB,HMGA2,MDM2,PARPBP,PTTG1IP,SENP2,TFIP11,THOC1,TRIP12 5.69 0.00591 0.116353899371069 GO:0006893 Golgi to plasma membrane transport biological_process 47 17 ANK3,ARFRP1,BBS1,BBS2,BLZF1,C16orf62,CNST,EXOC1,GCC2,GOLGA4,GOLGA7,KIF13A,LYPLA1,OSBPL5,PKDCC,SPTBN1,VAMP4 9.23 0.00602 0.117778791666667 GO:0032233 positive regulation of actin filament bu... biological_process 47 17 ARHGEF15,BAG4,BRAF,EVL,ITGB1BP1,LIMK1,MTOR,MYOC,NOX4,PAK1,PFN2,SORBS3,SYNPO,SYNPO2,TGFBR1,VIL1,WNT11 9.23 0.00602 0.117778791666667 GO:2000573 positive regulation of DNA biosynthetic ... biological_process 47 17 AURKB,DDX39B,GRHL2,MAP2K7,MAPKAPK5,NEK7,NOX4,NVL,PAK3,PDGFRB,PNKP,POT1,PTK2B,RFC2,RFC4,TCP1,TNKS 9.23 0.00602 0.117778791666667 GO:0030010 establishment of cell polarity biological_process 106 32 ARHGEF2,BCAS3,CENPA,CLASP1,DOCK7,FBF1,FERMT1,FOXJ1,FRMD4A,JAM3,KANK1,KRIT1,LLGL2,MARK1,MARK3,MYH9,MYO18A,NDE1,PAFAH1B1,PRKCZ,PTK2,PTK2B,RAB11FIP2,RAP1B,RUFY3,SDCCAG8,SHTN1,SPAG5,SPDL1,SPRY1,WDR43,WEE1 20.81 0.00608 0.118705363825364 GO:0051179 localization biological_process 5597 1160 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABI1,ABI3,ABR,ACACA,ACAP1,ACAP2,ACE,ACSL1,ACTG1,ACTN1,ACTR2,ADA,ADAM10,ADCYAP1,ADD3,ADIPOR1,ADIPOR2,ADORA1,ADPRHL1,AGFG1,AHCTF1,AHNAK,AIP,AKAP12,AKAP2,AKAP3,AKAP7,AKT1,AKTIP,ALOX15,AMPH,ANGPT2,ANGPTL3,ANK2,ANK3,ANKH,ANKRD53,ANKS1B,ANLN,ANO10,ANO2,ANO6,ANP32A,ANXA2,ANXA4,ANXA6,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APLP1,APOO,APPL1,APRT,AQP7,AQP8,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGAP4,ARHGEF16,ARHGEF2,ARID2,ARL1,ARL2BP,ARL6,ARMC1,ARMC4,ARPC1A,ARPC1B,ARPP19,ASIC2,ASPSCR1,ASUN,ATAD1,ATF4,ATG16L2,ATG3,ATG4B,ATL2,ATOH8,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATR,ATRX,ATXN2,AURKA,AURKB,AVL9,AZIN2,BAG4,BAIAP3,BANP,BAX,BBS1,BBS2,BCAR1,BCAS3,BCL2,BET1,BICD1,BIN2,BLK,BLZF1,BOK,BORA,BRAF,BSN,BTBD9,BTF3,BTK,BUB1B,C12orf4,C14orf166,C16orf45,C16orf62,C1QBP,C1QTNF5,C2,C2CD5,C3orf49,C4A,C4B,C5AR2,CA1,CA12,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CADPS2,CALM1,CAMK2A,CAMK2G,CAMSAP3,CARMIL2,CASK,CASP8,CATSPER4,CCDC14,CCDC88A,CCDC91,CCL25,CCZ1B,CD14,CD163,CD247,CD3G,CD44,CD6,CD74,CD81,CD9,CDC23,CDC42,CDH1,CDH13,CDH23,CDK5RAP3,CELSR1,CENPA,CENPQ,CEP290,CEP350,CEP57,CEP57L1,CERS2,CES1,CFAP20,CFAP46,CHD7,CHL1,CHMP3,CHMP5,CHMP6,CHRD,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHTOP,CLASP1,CLASP2,CLCC1,CLCN1,CLCN3,CLCNKA,CLDN7,CLEC4E,CLEC5A,CLN3,CLN8,CLTA,CLTC,CLU,CNGA1,CNIH1,CNIH2,CNNM1,CNST,CNTN1,COG2,COG5,COLEC11,COPA,COPB1,CORO7,COX17,COX5A,COX6A1,COX6B2,COX7A2L,CPLX2,CPNE1,CPNE3,CPT2,CRACR2A,CRBN,CRHBP,CROT,CRYAB,CRYM,CSE1L,CSF1R,CSF3R,CSNK1G1,CTDNEP1,CTDSPL2,CTNNA1,CTTNBP2NL,CUL3,CUX1,CXADR,CXCL12,CXCR2,CYB561,CYBB,CYFIP1,CYLD,CYP19A1,DAB2IP,DAG1,DAPK1,DAPK3,DBI,DCC,DCTN1,DCTN2,DCTN4,DCTN6,DDR1,DDR2,DDX20,DDX39B,DDX42,DENND1B,DENND4C,DGKZ,DLG2,DLG3,DMBT1,DMPK,DNAH11,DNAH17,DNAH2,DNAH3,DNAI1,DNAJA1,DNAJC1,DNAJC13,DNM1L,DNM3,DOCK4,DOCK7,DPCD,DPH3,DPP10,DRC1,DSCR3,DUOXA1,DUSP16,DYNC1I2,DYNC1LI1,DYRK2,DYSF,ECT2,EEA1,EFR3A,EGF,EGFR,EHD2,EIF2S3,EIF4E,EIF6,ELP5,ELP6,ENPP2,ENY2,EPB41L3,EPG5,EPHA4,ERC1,ERO1A,ESR1,ETV5,EVL,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,EXPH5,EZH2,FABP5,FADD,FAF1,FAM110C,FAM175B,FAM21A,FAT1,FBL,FBLN5,FBN1,FBXO22,FBXO7,FBXW11,FCGR1B,FCHO1,FCHO2,FERMT1,FES,FEZ1,FGF12,FGFR1,FGFR1OP,FHL1,FIP1L1,FKBP4,FMN2,FNBP1,FNBP1L,FNTA,FOXJ1,FRAS1,FRMD6,FUT8,FXYD1,FYB,GABRA5,GABRE,GABRG3,GABRP,GAK,GBP5,GCC2,GCGR,GCNT3,GCSAM,GDF9,GDI2,GET4,GGA1,GIF,GIPR,GJB1,GJC2,GLRA3,GLS,GLS2,GNA12,GNGT1,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPC3,GPIHBP1,GPM6A,GPR35,GPR89B,GRB10,GRB7,GRIA4,GRID1,GRM7,GSK3B,GSN,GSTP1,GTF2H2,GUK1,H2AFY,HACE1,HAP1,HDAC1,HDAC6,HDAC7,HDAC8,HDAC9,HDLBP,HEXB,HGS,HGSNAT,HMP19,HNRNPA2B1,HNRNPA3,HNRNPK,HOMER3,HOOK1,HOXA7,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HTR2B,HVCN1,HYAL1,ICA1,ICE1,IGF1R,IGF2BP3,IGF2R,IL1B,IL1R2,IL4R,IMMP2L,INPP5B,IP6K2,IPO11,IPO8,IPO9,ITGA2,ITGA6,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITPR1,ITSN2,JAM3,JMJD6,KALRN,KANK1,KAT7,KCNA6,KCNAB2,KCNB1,KCNIP4,KCNK6,KCNMA1,KCNN2,KDELR2,KEL,KIAA0753,KIF13A,KIF15,KIF1A,KIF1BP,KIF23,KLHL20,KLHL24 1098.91 0.00615 0.119822925311203 GO:0042559 pteridine-containing compound biosynthet... biological_process 16 8 ATIC,DHFR,GART,MTHFD1,MTHFD2L,PCBD1,PTS,QDPR 3.14 0.00621 0.120243525773196 GO:0043981 histone H4-K5 acetylation biological_process 16 8 JADE1,KANSL1,KANSL1L,KANSL2,KAT7,MEAF6,OGT,PHF20 3.14 0.00621 0.120243525773196 GO:0043982 histone H4-K8 acetylation biological_process 16 8 JADE1,KANSL1,KANSL1L,KANSL2,KAT7,MEAF6,OGT,PHF20 3.14 0.00621 0.120243525773196 GO:0009451 RNA modification biological_process 131 38 ADAT2,APOBEC3F,BAG4,CDKAL1,CMTR2,DIMT1,FBL,METTL1,METTL14,METTL15,METTL16,MTO1,NAT10,NOP10,NOP2,NOP56,NOP58,NSUN4,PARN,PDCL3,QTRT1,RPUSD1,RPUSD4,RRNAD1,SSB,TARBP1,TFB1M,THUMPD1,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,TRUB1,TYW5,UBA5,WTAP 25.72 0.00624 0.120274077868852 GO:0046654 tetrahydrofolate biosynthetic process biological_process 5 4 ATIC,DHFR,GART,MTHFD1 0.98 0.00625 0.120274077868852 GO:0051534 negative regulation of NFAT protein impo... biological_process 5 4 DYRK2,GSK3B,MTOR,TBC1D10C 0.98 0.00625 0.120274077868852 GO:0032367 intracellular cholesterol transport biological_process 13 7 ABCA2,CES1,LDLRAP1,LRP6,STAR,STARD4,VPS4A 2.55 0.00628 0.120604253578732 GO:0033238 regulation of cellular amine metabolic p... biological_process 86 27 ABAT,ATP2B4,DUOXA1,HPRT1,OAZ1,OAZ2,PDE1B,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4 16.89 0.00633 0.121316387755102 GO:0048193 Golgi vesicle transport biological_process 332 84 ANK2,ANK3,AP1G1,ARF1,ARFGAP2,ARFRP1,ARL1,ATL2,ATP9B,BBS1,BBS2,BET1,BLZF1,C16orf62,CNIH1,CNIH2,CNST,COG2,COG5,COPA,COPB1,CORO7,CUL3,CUX1,DCTN1,DCTN2,DCTN4,DCTN6,DYNC1I2,EXOC1,GAK,GCC2,GOLGA4,GOLGA7,GORASP1,KDELR2,KIF13A,KIF15,KIF23,KLHL20,LYPLA1,MCFD2,MIA3,MON2,MPPE1,MYO18A,MYO1B,NAPG,OSBPL5,PICK1,PITPNB,PKDCC,PPP6R3,PREB,RAB1A,RAB2A,RACGAP1,RGPD1,RGPD5,RP2,SCFD1,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SNAP23,SNX2,SORL1,SPTB,SPTBN1,SPTBN4,STX5,TGFA,TMED2,TRAPPC2B,TRAPPC8,UVRAG,VAMP4,VPS13A,VPS13C,VPS54,YKT6 65.18 0.00637 0.121834358452138 GO:0006275 regulation of DNA replication biological_process 165 46 ATR,ATRX,AURKB,CCDC88A,CCT3,CCT7,CDC42,CDC6,CTC1,DNA2,E2F7,EGFR,EHMT2,GLI1,GRHL2,HNRNPC,HNRNPU,HUS1,IGF1R,INO80,LIG3,MAP2K4,MAP2K7,MAPKAPK5,NAT10,NEK7,NPM2,NUCKS1,NVL,PNKP,POT1,PPP2R1A,RAD17,RBBP6,RFC2,RFC4,SENP2,SMC1A,SMG6,TCP1,TGFB1,TNKS,TTF1,WAPL,WIZ,ZRANB3 32.4 0.00640 0.122102048681542 GO:0000245 spliceosomal complex assembly biological_process 51 18 CRNKL1,DDX1,DDX23,DDX39B,LUC7L,LUC7L3,PRPF39,PSIP1,PTBP2,SART3,SCAF11,SF1,SF3B1,SNRPE,SRPK2,SRSF5,TXNL4B,USP39 10.01 0.00641 0.122102048681542 GO:0010977 negative regulation of neuron projection... biological_process 123 36 ARHGAP4,ARHGEF1,CERS2,DCC,DNM3,EPHA4,EPHB2,FKBP4,GAK,GORASP1,GSK3B,HDAC2,IFRD1,ITM2C,KANK1,KLK8,MDM2,NLGN3,PAFAH1B1,PAQR3,PTEN,PTK2,RAP1GAP2,RAPGEF2,RGMA,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SNAPIN,THY1,ULK2 24.15 0.00654 0.124326194331984 GO:0051348 negative regulation of transferase activ... biological_process 355 89 AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CDC23,CDC27,CDK5RAP3,CHAD,CHORDC1,CTC1,DAB2IP,DNAJA1,DUSP16,DUSP9,DYNC1LI1,EIF4A2,FBXO7,FGFR1OP,FZR1,GBAS,GEN1,GMFB,GMFG,GSK3B,GSTP1,H2AFY,HIPK3,IGF1R,IL1B,ITGB1BP1,KAT2B,LCMT1,LIMK1,LRP6,LRRTM1,LRRTM3,MIDN,MVP,NCK1,NF1,PAK2,PAQR3,PODN,POT1,PPP1R1B,PPP2R1A,PRKAR2A,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTEN,PTPN2,PTPN6,RANBP2,RGN,RGS14,RGS3,RTN4RL2,SMYD3,SORL1,SPRY1,TARBP2,TEX14,THY1,TTK,UBA52,UBE2E1,WWTR1,XRCC3,ZNF207 69.7 0.00663 0.125782484848485 GO:0008608 attachment of spindle microtubules to ki... biological_process 26 11 AURKB,CDC42,ECT2,FAM175B,RACGAP1,SEH1L,SGO1,SIRT2,SPAG5,TEX14,ZNF207 5.1 0.00681 0.128936915322581 GO:0000289 nuclear-transcribed mRNA poly(A) tail sh... biological_process 33 13 AGO2,CNOT2,CNOT7,CNOT8,CPEB3,EIF4A1,EIF4A2,EIF4B,EIF4E,PABPC1,PAN3,PARN,POLR2G 6.48 0.00692 0.130493413654618 GO:0006370 7-methylguanosine mRNA capping biological_process 33 13 CDK7,CMTR2,GTF2H2,GTF2H3,GTF2H5,MNAT1,NCBP2,NCBP3,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K 6.48 0.00692 0.130493413654618 GO:0051298 centrosome duplication biological_process 59 20 BRCA1,CENPJ,CEP135,CEP192,CEP63,CHMP3,CHMP5,CHORDC1,GEN1,KIAA0753,MDM1,NDE1,OFD1,PLK4,SASS6,TMEM67,TUBGCP5,USP33,XPO1,XRCC3 11.58 0.00699 0.131549278557114 GO:0000902 cell morphogenesis biological_process 1176 264 ABI1,ABLIM3,ACTN1,ACTR2,ADIPOR1,ADNP,AKIP1,ANK3,ANTXR1,ANXA7,APBB1,APBB2,ARHGAP4,ARHGEF1,ARHGEF2,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BBS1,BBS2,BCL2,BMPR1B,BOC,BRAF,BRWD3,C1QBP,CACNA1A,CAMK2A,CAPRIN1,CCDC114,CDC42,CDC42EP3,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CHL1,CHN1,CHRNA3,CLASP1,CLASP2,CLU,COBL,CRTAC1,CSF1R,CSNK1G1,CTNNA1,CUL3,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DAPK3,DCC,DHFR,DICER1,DNAI1,DNAI2,DNM3,DOCK7,DRC1,ECT2,EGFR,ENPP2,EPB41L3,EPHA4,EPHB2,ETV1,EVL,EZH2,FAM161A,FARP1,FBF1,FBLIM1,FES,FEZ1,FEZ2,FGD3,FGD4,FGD6,FMN1,FMNL2,FNBP1L,FOXJ1,FRMD6,FRY,FRYL,GALNT11,GNA12,GOLGA4,GORASP1,GPC1,GPM6A,GRHL2,GSK3B,GSN,HDAC2,HDAC6,HEXB,HEYL,HMGA2,HPRT1,HSPB11,IFRD1,IQCB1,IQCG,ITGA7,ITGAV,ITGB1BP1,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LARP4,LGI1,LHX9,LIF,LIMD1,LIMK1,LINGO3,LRP6,MAP1S,MAP2,MAP6,MAPK8IP3,MEF2A,MEF2C,METRN,MINK1,MKLN1,MKS1,MSX2,MYH10,MYH9,MYO10,MYOC,NECTIN1,NLGN3,NME5,NOX4,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,ONECUT2,PAFAH1B1,PAK1,PAK3,PALLD,PAX2,PAX3,PCM1,PEAK1,PHIP,PHLDB1,PLA2G10,PLOD3,PLXNA1,PLXNB1,PLXNC1,PLXND1,POC1B,PRPF40A,PRRX1,PTEN,PTK2,PTK2B,PTPN6,PTPRA,RAB1A,RADIL,RAPGEF2,RAPH1,RBPJ,RELN,RFX2,RGMA,RNF6,ROBO1,ROBO3,RP2,RPGR,RSPH9,RTN4,RTN4RL2,RUFY3,SART3,SCFD1,SDCBP,SDHAF2,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SGK1,SHTN1,SIDT2,SKIL,SLC11A2,SLC1A3,SMAD2,SMAD4,SNX2,SOS1,SOX6,SPAG16,SPINT2,SPTB,SPTBN1,SPTBN4,SS18,SSX2IP,STK25,STRAP,STRC,SZT2,TAPT1,TGFB1,TGFB1I1,TGFBR1,THY1,TLR9,TMEM237,TMEM67,TOP2B,TPGS1,TRIOBP,TROVE2,TTC21B,UBE2B,ULK2,UNK,USP33,USP9X,VEGFA,VIL1,WEE1,WNT11,WWTR1,ZMYM2,ZNF135,ZNF280D,ZNF385A 230.9 0.00710 0.1333522 GO:0043486 histone exchange biological_process 44 16 ANP32A,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,ITGB3BP,MIS18BP1,NASP,PSME4,RBBP4,RBBP7,RNF8,SMARCA5,SYCP3 8.64 0.00716 0.134210698602794 GO:0030521 androgen receptor signaling pathway biological_process 63 21 BRCA1,BUD31,CDK7,DNAJA1,FKBP4,HDAC1,HDAC6,HEYL,MED13,MED14,MED16,MED24,MED30,NCOA1,PIAS1,RNF14,RNF4,RNF6,TGFB1I1,THRAP3,UBE3A 12.37 0.00719 0.134504561752988 GO:0006368 transcription elongation from RNA polyme... biological_process 95 29 BRD4,CCNT1,CCNT2,CDK7,CTR9,EAPP,ELL2,ELP2,ELP4,ENY2,EZH2,GTF2B,GTF2H2,GTF2H3,GTF2H5,LEO1,MNAT1,NCBP2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,RECQL5,RNF8,SUPT4H1,TAF2,TCEB1,THOC7 18.65 0.00738 0.137511071428571 GO:0007034 vacuolar transport biological_process 95 29 AKTIP,AP1G1,ATP6V0D1,CHMP5,CLN3,FGFR1,GAK,GCC2,GNPTG,HGS,HGSNAT,HOOK1,KIF13A,M6PR,MGRN1,NAGPA,SCYL2,SNAPIN,SNX16,SORL1,STX8,TRAK1,TRAPPC8,VPS11,VPS13A,VPS13C,VPS36,VPS54,ZFYVE16 18.65 0.00738 0.137511071428571 GO:0044766 multi-organism transport biological_process 75 24 AAAS,CHMP5,DDX39B,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,TCP1,THOC1,THOC2,THOC7,UBA52,VTA1,XPO1 14.73 0.00750 0.139194664031621 GO:1902579 multi-organism localization biological_process 75 24 AAAS,CHMP5,DDX39B,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,TCP1,THOC1,THOC2,THOC7,UBA52,VTA1,XPO1 14.73 0.00750 0.139194664031621 GO:0006420 arginyl-tRNA aminoacylation biological_process 3 3 DALRD3,RARS,RARS2 0.59 0.00756 0.139207764705882 GO:0070627 ferrous iron import biological_process 3 3 SLC11A2,TF,TFR2 0.59 0.00756 0.139207764705882 GO:0090234 regulation of kinetochore assembly biological_process 3 3 RNF4,SENP6,TRAPPC12 0.59 0.00756 0.139207764705882 GO:2001038 regulation of cellular response to drug biological_process 3 3 HMGA2,KMT2A,NCOA1 0.59 0.00756 0.139207764705882 GO:0065004 protein-DNA complex assembly biological_process 201 54 ANP32A,ATF7IP,ATRX,BRD2,CABIN1,CAND1,CDK7,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CUL4B,DDB1,DMC1,GTF2H2,GTF2H3,GTF2H5,H2AFY,HAT1,HELLS,HIST1H2BN,ITGB3BP,KAT6A,MCM2,MIS18BP1,MNAT1,NAA60,NAP1L1,NAP1L4,NASP,PIAS1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RAD51C,RAD52,RBBP4,RBBP7,RNF4,RPA3,SART3,SENP6,SMARCA5,SMYD3,TAF1B,TAF2,TRAPPC12,UBA52,WNT10B,XRCC3 39.46 0.00758 0.1393028962818 GO:0034047 regulation of protein phosphatase type 2... biological_process 23 10 ANKLE2,ARPP19,EIF2AK2,MASTL,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E 4.52 0.00778 0.1426991796875 GO:0031103 axon regeneration biological_process 37 14 BCL2,BRAF,CERS2,CHL1,CTNNA1,DHFR,EPHA4,JAM3,KLK8,NREP,NTRK3,PTEN,RGMA,RTN4RL2 7.26 0.00780 0.142787134502924 GO:1902806 regulation of cell cycle G1/S phase tran... biological_process 133 38 AKT1,AURKA,BAX,BCL2,BRD7,CDC6,CENPJ,CNOT2,CNOT7,CNOT8,CUL4B,E2F7,EGFR,EZH2,FBXO7,FHL1,GIGYF2,INO80,JADE1,KANK2,MDM2,MDM4,MTBP,MYO16,PCBP4,PLCB1,PLK3,PLRG1,PRMT1,PSME3,PTEN,PTPN6,RFWD3,SENP2,TP63,UBA52,UBE2E2,ZNF385A 26.11 0.00815 0.148614854368932 GO:2000045 regulation of G1/S transition of mitotic... biological_process 133 38 AKT1,AURKA,BAX,BCL2,BRD7,CDC6,CENPJ,CNOT2,CNOT7,CNOT8,CUL4B,E2F7,EGFR,EZH2,FBXO7,FHL1,GIGYF2,INO80,JADE1,KANK2,MDM2,MDM4,MTBP,MYO16,PCBP4,PLCB1,PLK3,PLRG1,PRMT1,PSME3,PTEN,PTPN6,RFWD3,SENP2,TP63,UBA52,UBE2E2,ZNF385A 26.11 0.00815 0.148614854368932 GO:1903506 regulation of nucleic acid-templated tra... biological_process 3495 737 ABCA2,ABLIM3,ACAD8,ACOD1,ACTL6A,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,EIF4A2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUP107,NUP35,OGT,ONECUT2,OTULIN,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1,PTPRK,PTPRN,PURA,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM39,RBMX,RBPJ,RBPMS,RECQL5,RELN,RFX2,RFX5,RFX7,RGMA,RGS14,RLF,RNF14,RNF2,RNF25,RNF4,RNF44,RNF6,RNF8,RORC,RPL6,RPS6KA1,RRP8,RUNX1T1,RXRA,RYR2,SAP18,SAP25,SAP30BP,SBNO1,SCAI,SCAP,SEMA4D,SENP2,SF1,SFPQ,SGK1,SIM1 686.21 0.00819 0.149054825581395 GO:0043087 regulation of GTPase activity biological_process 653 153 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DOCK4,ECT2,EGF,EGFR,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GSK3B,HACD3,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,MTOR,NCK1,NF1,NPRL3,NTRK2,OCRL,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TMED2,TNK2,TRIO,TRIP10,USP6NL,VAV1,WNT11 128.21 0.00821 0.149129806576402 GO:0006810 transport biological_process 4452 929 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABI1,ABR,ACACA,ACAP1,ACE,ACSL1,ACTG1,ACTN1,ACTR2,ADA,ADCYAP1,ADD3,ADIPOR2,ADORA1,ADPRHL1,AGFG1,AHCTF1,AHNAK,AIP,AKAP12,AKAP3,AKT1,AKTIP,ALOX15,AMPH,ANK2,ANK3,ANKH,ANO10,ANO2,ANO6,ANP32A,ANXA2,ANXA4,ANXA6,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APLP1,APOO,APPL1,APRT,AQP7,AQP8,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGEF2,ARL1,ARL2BP,ARL6,ARMC1,ARPC1A,ARPC1B,ARPP19,ASIC2,ASPSCR1,ATAD1,ATF4,ATG16L2,ATG3,ATG4B,ATL2,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATXN2,AZIN2,BAIAP3,BAX,BBS1,BBS2,BCAS3,BCL2,BET1,BICD1,BIN2,BLK,BLZF1,BOK,BRAF,BTBD9,BTF3,BTK,C12orf4,C14orf166,C16orf62,C1QTNF5,C2,C2CD5,C3orf49,C4A,C4B,C5AR2,CA1,CA12,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CADPS2,CALM1,CAMK2A,CAMK2G,CASK,CASP8,CATSPER4,CCDC91,CCZ1B,CD14,CD163,CD247,CD3G,CD6,CD74,CD81,CD9,CDC42,CDH1,CDH13,CDH23,CEP290,CEP57,CES1,CHD7,CHMP3,CHMP5,CHMP6,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHTOP,CLASP1,CLASP2,CLCC1,CLCN1,CLCN3,CLCNKA,CLEC4E,CLEC5A,CLN3,CLN8,CLTA,CLTC,CLU,CNGA1,CNIH1,CNIH2,CNNM1,CNST,CNTN1,COG2,COG5,COLEC11,COPA,COPB1,CORO7,COX17,COX5A,COX6A1,COX6B2,COX7A2L,CPLX2,CPNE1,CPNE3,CPT2,CRACR2A,CRBN,CRHBP,CROT,CRYAB,CRYM,CSE1L,CSF1R,CSNK1G1,CTDSPL2,CTTNBP2NL,CUL3,CUX1,CXADR,CXCL12,CXCR2,CYB561,CYBB,CYFIP1,CYLD,DAB2IP,DAG1,DAPK1,DBI,DCTN1,DCTN2,DCTN4,DCTN6,DDR1,DDX20,DDX39B,DENND1B,DENND4C,DLG3,DMBT1,DMPK,DNAJA1,DNAJC1,DNAJC13,DNM1L,DNM3,DPH3,DPP10,DSCR3,DUOXA1,DUSP16,DYNC1I2,DYNC1LI1,DYRK2,DYSF,ECT2,EEA1,EGF,EGFR,EHD2,EIF2S3,EIF4E,EIF6,ENPP2,ENY2,EPG5,ERC1,ERO1A,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,EXPH5,FABP5,FAF1,FAM21A,FBLN5,FBXO22,FBXO7,FBXW11,FCGR1B,FCHO1,FCHO2,FES,FEZ1,FGF12,FGFR1,FHL1,FIP1L1,FKBP4,FMN2,FNBP1,FNBP1L,FRAS1,FXYD1,FYB,GABRA5,GABRE,GABRG3,GABRP,GAK,GBP5,GCC2,GCGR,GCNT3,GDF9,GDI2,GET4,GGA1,GIF,GIPR,GJB1,GJC2,GLRA3,GLS,GLS2,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPC3,GPIHBP1,GPM6A,GPR35,GPR89B,GRB10,GRIA4,GRID1,GRM7,GSK3B,GSN,GTF2H2,GUK1,HAP1,HDAC1,HDAC6,HDLBP,HGS,HGSNAT,HMP19,HNRNPA2B1,HNRNPA3,HNRNPK,HOMER3,HOOK1,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HTR2B,HVCN1,ICA1,ICE1,IGF2BP3,IGF2R,IL1B,IL1R2,IL4R,IMMP2L,IP6K2,IPO11,IPO8,IPO9,ITGA2,ITGAL,ITGAV,ITGB1BP1,ITPR1,ITSN2,JMJD6,KALRN,KANK1,KCNA6,KCNAB2,KCNB1,KCNIP4,KCNK6,KCNMA1,KCNN2,KDELR2,KEL,KIF13A,KIF15,KIF1A,KIF1BP,KIF23,KLHL20,KLHL24,KLHL3,KMT2A,LAMP2,LAMTOR1,LAPTM4B,LAT,LCN10,LCN12,LCN2,LCP1,LDLRAD3,LDLRAP1,LGR4,LIF,LIMK1,LITAF,LLGL2,LMBR1L,LOXL4,LRAT,LRP6,LRPPRC,LRRTM1,LTF,LTV1,LYNX1,LYPLA1,LYST,LZTS2,M6PR,MAGOHB,MAL2,MALT1,MAP1S,MAP4K2,MAP6,MAPK8,MAPK8IP3,MCFD2,MCUR1,MDM2,MEF2C,MEGF10,MFF,MFGE8,MFSD14A,MFSD2A,MGRN1,MIA3,MIDN,MINK1,MIP,MITD1,MLPH,MON2,MPPE1,MRC2,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTOR,MTTP,MTX1,MTX2,MTX3,MVP,MYH10,MYH9,MYLK,MYO10,MYO18A,MYO1B,MYO1G,NAGPA,NAPB,NAPG,NASP,NCBP2,NCBP3,NCK1,NCKIPSD,NCOA1,NCOA2,NCOR1,NDC1,NDE1,NDUFA9,NDUFAF6,NECTIN1,NEDD4L,NF1,NFE2L2,NIPAL1,NISCH,NKAIN4,NLGN3,NLRP12,NME4,NMT1,NNT,NOP58,NOS3,NOX1,NOX5,NPLOC4,NPTX1,NRXN1,NTRK2 874.1 0.00834 0.151198725868726 GO:0032259 methylation biological_process 340 85 AMT,ARID4A,ASH1L,ATF7IP,ATRX,BAZ2A,BRCA1,CHTOP,CMTR2,CTR9,DIMT1,DOT1L,DPH5,EHMT1,EHMT2,EZH2,FBL,FBXO11,FKBP6,GATAD2A,GATAD2B,GCSH,GRHL2,GSK3B,H2AFY,HELLS,KDM1B,KDM6A,KMT2A,KMT2D,KMT2E,LCMT1,MAT2A,MBD3,METTL1,METTL14,METTL15,METTL16,METTL21A,METTL22,METTL23,METTL5,MTF2,MTO1,MTRR,MYB,NDUFAF7,NOP2,NSUN4,NSUN7,OGT,PAX7,PAXBP1,PCMT1,PCMTD1,PHF1,PICK1,PIK3CA,PIWIL4,PNMT,PRDM16,PRMT1,PRMT3,PRMT5,PWP1,RLF,RRNAD1,RRP8,SMAD4,SMYD2,SMYD3,TARBP1,TDRD5,TFB1M,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,TYMS,USP7,WHSC1,WHSC1L1,WTAP 66.76 0.00844 0.152423153846154 GO:0051056 regulation of small GTPase mediated sign... biological_process 295 75 ABR,ARAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CDC42,CDON,CHN1,CUL3,CYTH4,DAB2IP,ECT2,EPS8L1,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,GDI2,GMIP,GPR35,INPP5B,ITSN2,KALRN,KANK1,KRAS,MADD,MCF2,MCF2L,MYOC,NF1,OCRL,OGT,P2RY8,PDCD10,PDGFRB,PIK3R2,PLEKHG2,PLEKHG6,PSD3,PSD4,RAC2,RACGAP1,RALGAPB,RAP1GAP2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP4,RELN,RHOC,RHOF,RHOT1,ROBO1,SCAI,SGSM3,SIPA1,SOS1,SPATA13,SPRY1,SSX2IP,STAMBP,TRIO,TRIP10,VAV1 57.92 0.00844 0.152423153846154 GO:0046777 protein autophosphorylation biological_process 224 59 AAK1,ACE,AKT1,ATR,AURKA,AURKB,BLK,BTK,CALM1,CAMK2A,CAMK2G,CDK12,CLK2,CSF1R,DAPK1,DAPK3,DDR1,DDR2,EGFR,EIF2AK2,EPHA4,FES,FGFR1,GFRA2,GSK3B,IGF1R,IMPACT,IRAK1,MAP3K12,MAP3K3,MAP4K1,MAPKAPK5,MELK,MINK1,MKNK1,MTOR,MVP,NEK10,NLRP12,NTRK2,NTRK3,PAK1,PAK2,PDGFRB,PEAK1,PTK2,PTK2B,ROS1,SMG1,STK10,STK25,THY1,TNK2,TOM1L1,TRPM7,TYK2,ULK2,VEGFA,ZAP70 43.98 0.00849 0.153031842610365 GO:0035556 intracellular signal transduction biological_process 2528 541 ABR,ADA,ADCY10,ADCY4,ADCYAP1,ADIPOR1,ADORA1,AGO1,AGO2,AIP,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKR1B1,AKT1,ALOX15,ANK2,ANKRD6,ANP32A,APBB2,ARAP2,ARF1,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL5C,ARL6,ARL8A,ASB15,ASH1L,ATF4,ATP1B1,ATP2B4,ATP2C1,ATR,ATRX,AURKA,AURKB,AZI2,BAG4,BANP,BAX,BBC3,BCL2,BCLAF1,BIRC3,BIRC7,BLK,BLNK,BOK,BRAF,BRCA1,BRD4,BRD7,BRIP1,BTK,C1QBP,C3orf33,C5AR2,CACNA1C,CALM1,CAMK2A,CAMK2G,CAPS,CASP4,CASP8,CCDC88A,CCDC88C,CCL25,CD14,CD44,CD74,CD81,CDC42,CDC42EP3,CDH13,CDK12,CDK5RAP3,CDON,CELSR1,CENPJ,CEP63,CFLAR,CHAD,CHD3,CHN1,CHRNA7,CHUK,CNOT2,CNOT7,CNOT8,CPNE1,CRYAB,CSF1R,CSNK2A1,CSNK2A2,CTR9,CUL1,CUL3,CYFIP1,CYLD,CYTH4,DAB2IP,DAG1,DAPK1,DAPK3,DCDC1,DEPDC1,DEPDC4,DGKA,DGKG,DGKZ,DIABLO,DMPK,DNA2,DNAJA1,DNAJC10,DNM1L,DOCK4,DOCK7,DOK4,DOT1L,DUSP16,DUSP9,DYRK2,E2F7,ECT2,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2AK2,ELP2,EPHA4,EPS8L1,ERC1,ERO1A,ESR1,EXOC1,EZH2,FADD,FAF1,FAM110C,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FAS,FBXW11,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FKBP8,FMN2,FRS2,FYB,GADD45G,GDF9,GDI2,GFRA2,GMIP,GNA12,GPR35,GPRC5B,GRAP,GSK3B,GSTP1,HACD3,HACE1,HAP1,HAVCR2,HDAC1,HDAC2,HDAC7,HGS,HIPK3,HTR2B,HUS1,IFNL2,IGF1R,IL15,IL1B,IL22RA2,IL2RA,INPP5A,INPP5B,IRAK1,IRAK4,ITGAV,ITGB1BP1,ITPR1,ITSN2,KALRN,KANK1,KAT6A,KRAS,KRIT1,KSR2,L3MBTL1,LAMTOR1,LAMTOR3,LAT,LCP1,LIF,LIMD1,LIMK1,LITAF,LMO3,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MARVELD3,MASTL,MBD3,MCF2,MCF2L,MCTP1,MDM2,MDM4,MEAF6,MEF2A,MEF2C,MELK,MGRN1,MIER1,MINK1,MKNK1,MOB1A,MST1R,MTDH,MTOR,MYOC,NCOR1,NDRG2,NEK10,NEK11,NF1,NFATC1,NFKBID,NISCH,NLRP12,NMI,NOS3,NOX1,NOX4,NPRL3,NRAS,NSMCE1,NTRK2,NTRK3,OCRL,OGT,OPRK1,OPRM1,OSBPL8,OTULIN,P2RX5,P2RY12,P2RY8,PABPN1,PAFAH1B1,PAK1,PAK3,PAQR3,PAX2,PBK,PCBP4,PDCD10,PDE2A,PDE4D,PDE5A,PDE9A,PDGFRB,PDZD3,PELI1,PEX5L,PHF20,PIAS1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R5,PIN1,PIP5K1A,PIP5K1C,PLA2G4B,PLA2G4C,PLA2G5,PLCB1,PLCB2,PLCB4,PLCD3,PLCD4,PLCH1,PLD1,PLEK2,PLEKHG2,PLEKHG6,PLEKHM1,PLK3,PLXNB1,PODN,POLB,PPM1B,PPP1R1B,PPP2R1A,PPP2R5C,PPP4C,PRDX4,PRKAR2A,PRKCZ,PRLR,PRMT1,PRMT5,PRR5L,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPN13,PTPN2,PTPN6,PTPRA,PTTG1IP,PUM2,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB30,RAB40B,RAB5A,RABL2A,RABL6,RAC2,RACGAP1,RAD17,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RBBP4,RBBP7,RBBP8,RBCK1,RBM4,RELN,RELT,RFC2,RFC4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RHOF,RHOT1,RIT1,RMI1,ROBO1,ROS1,RPA3,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RRAGB,RRAS2,RRP8,RTN4RL2,RYR2,SASH1,SCAI,SDCBP,SEC14L1,SEH1L,SEMA4D,SEMA7A,SENP2,SEPT4,SERPINA12,SGK1,SGSM3,SH2B3,SH2D3C,SH2D6,SHC2,SHTN1,SIPA1,SIRT2,SLC38A9,SMAD2,SMAD4,SMC1A,SMYD2,SORBS3,SORL1,SOS1,SPAG9,SPATA13,SPRY1,SPSB4,SPTB,SPTBN1,SPTBN4,SRPK2,SS18,SSX2IP,STAC,STAMBP,STAP2,STK17A,STK25,STK32B,TAB2,TAB3,TAF2,TANK,TBC1D10C,TBK1,TEAD1,TELO2,TGFA,TGFB1,TGFBR1,TIFA,TLK2 496.35 0.00852 0.153278390804598 GO:0048583 regulation of response to stimulus biological_process 3497 737 AAAS,AAK1,ABAT,ABI1,ABR,ACOD1,ACTG1,ACTR2,ADA,ADAM10,ADCYAP1,ADIPOR1,ADORA1,AGO1,AIP,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKR1B1,AKT1,ALOX15,AMBRA1,AMER1,AMER3,ANGPT2,ANKRD10,ANKRD6,ANO6,ANXA2,AP1G1,AP1M2,AP1S2,APBB1,APOBEC3F,ARAP2,ARF1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL2BP,ARL6,ARPC1A,ARPC1B,ASH1L,ASIC2,ATP2B4,ATP2C1,ATP6V0D1,ATP6V1C2,ATR,ATXN7,AURKA,AURKB,BAG4,BANP,BAX,BBC3,BBS2,BCAR1,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLK,BLNK,BOK,BPIFB1,BRAF,BRCA1,BRD4,BRD7,BRIP1,BTK,BUD31,C12orf4,C1QBP,C1RL,C1S,C2,C2CD5,C3orf33,C4A,C4B,C5AR2,CACNB3,CALCOCO2,CALM1,CAMK2A,CAMK2G,CASK,CASP4,CASP8,CCL25,CD14,CD160,CD1B,CD200,CD247,CD3G,CD44,CD46,CD6,CD74,CD79B,CD81,CDC42,CDH13,CDK12,CDK5RAP3,CDON,CERS2,CFAP20,CFLAR,CHAD,CHD3,CHID1,CHN1,CHORDC1,CHRD,CHRNA7,CHUK,CLEC2B,CLEC2D,CLEC4E,CLN3,CLTA,CLU,CNGA1,CNIH2,CNOT2,COL17A1,COLEC11,CPNE1,CR1,CRHBP,CRYAB,CSF1R,CSNK2A1,CSNK2A2,CTDNEP1,CTDSPL2,CTNNA1,CTNND1,CUL1,CUL3,CXADR,CXCL12,CXCR2,CXXC4,CYFIP1,CYLD,CYP19A1,CYTH4,DAB2IP,DAG1,DAPK1,DAPK3,DDIT4L,DDX39B,DENND1B,DHFR,DMBT1,DNA2,DNAJA1,DNM1L,DOT1L,DROSHA,DTX1,DUOXA1,DUSP16,DUSP9,DYRK2,ECT2,EEF1D,EGF,EGFL7,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,ELF1,ELP2,ENY2,EPHA4,EPS8L1,ESR1,EXOC1,EXOC4,EYA3,EYA4,EZH2,FADD,FAF1,FAM110C,FAM13B,FAM150A,FAM58A,FANCA,FANCD2,FARP1,FARP2,FAS,FBLN5,FBN1,FBXW11,FCER2,FCGR1B,FES,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FKBP4,FKBP8,FNTA,FOXJ1,FRS2,FUT8,FYB,FZD6,GADD45G,GALNT11,GBP5,GCLC,GCLM,GCSAM,GDF9,GDI2,GGT1,GIPR,GLI1,GLRX2,GMIP,GNA12,GNG4,GNG7,GNGT1,GPC1,GPC3,GPR35,GPRC5B,GPSM1,GRAP,GRB10,GRB7,GRK6,GSK3B,GSN,GSTP1,GTF2H2,GTF2I,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HELB,HERC5,HEYL,HGS,HIPK3,HLA-DMB,HLA-DPB1,HMGA2,HSP90B1,HSPA8,HSPD1,HSPH1,HTR2B,HUS1,IDO1,IFNL2,IGF1R,IGFBP2,IL15,IL18BP,IL1B,IL1R2,IL22RA2,IL2RA,IL4R,IMPACT,INPP5B,IRAK1,IRAK4,ITGA2,ITGA6,ITGAL,ITGAV,ITGB1BP1,ITM2C,ITPR1,ITSN2,JADE1,JAM3,KALRN,KANK1,KANK2,KAT6A,KLHL24,KLK8,KLRD1,KMT2A,KMT2D,KRAS,L3MBTL1,LAMTOR1,LAMTOR3,LANCL2,LAT,LDLRAP1,LFNG,LGR4,LGR5,LIF,LIMD1,LIMK1,LIMS2,LITAF,LLGL2,LMO3,LRP6,LRRTM1,LRRTM3,LTA,LTBP1,LTF,LYNX1,LZTS2,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARVELD3,MBD3,MBD5,MCF2,MCF2L,MDM2,MDM4,MEAF6,MED16,MEF2A,MEF2C,METAP2,MFF,MFNG,MGRN1,MIER1,MINK1,MKS1,MMP28,MMRN2,MST1R,MSX2,MTA1,MTCH1,MTDH,MTOR,MYB,MYLK,MYO10,MYO1G,MYOC,NCK1,NCKIPSD,NCOA1,NCOA2,NCOR1,NCR1,NDC1,NDRG2,NEK10,NEPRO,NF1,NFATC1,NFE2L2,NFKBID,NKD1,NLGN3,NLRC5,NLRP12,NMI,NMT1,NOS3,NOX1,NOX4,NPRL3,NR2C1,NRAS,NREP,NRXN1,NSMCE1,NSMCE4A,NTRK2,NTRK3,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OCRL,OGT,ONECUT2,OPA1,OPRK1,OPRM1,OSBPL8,OSCAR,OSMR,OTULIN,P2RX5,P2RY8,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PARPBP,PAWR,PBK,PCBP2,PDCD10,PDCD5,PDE2A,PDE4D,PDE5A,PDE6B,PDE9A,PDGFRB,PEAR1,PELI1,PEX5L,PGLYRP2,PHF14,PHF20,PHIP,PIAS1,PIGR,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIN1,PIP5K1A,PIP5K1C,PLA2G5,PLCB1,PLEKHG2,PLEKHG6,PLK3,PLXNA1,PLXNB1,PLXNC1,PLXND1,PNPT1,PODN,POGLUT1,POLR3C,POLR3F,POR,PPM1B 686.6 0.00862 0.154780917782027 GO:0006612 protein targeting to membrane biological_process 185 50 ADORA1,ANK2,ANK3,ANXA2,ARL6,ATG3,ATG4B,C2CD5,GOLGA7,ITGB1BP1,KCNB1,MFF,NUP155,NUP54,PACS2,PDZK1,PEX16,PEX3,PIP5K1A,RAB3IP,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SDCBP,SEC63,SPTBN1,SRP19,SSR1,SSR2,SSR3,TMED2,TRAM1,UBA52 36.32 0.00878 0.156635464895636 GO:0047496 vesicle transport along microtubule biological_process 20 9 CLN3,HAP1,KIF13A,KIF23,NDE1,PAFAH1B1,PRKCZ,RAB1A,WDR43 3.93 0.00878 0.156635464895636 GO:0051984 positive regulation of chromosome segreg... biological_process 20 9 CDC6,CUL3,H2AFY,NSMCE2,RAD18,SFPQ,SIRT2,SLF1,SMC6 3.93 0.00878 0.156635464895636 GO:0045089 positive regulation of innate immune res... biological_process 291 74 ACOD1,AP1G1,BIRC3,BPIFB1,BTK,C1QBP,CASP8,CD14,CHUK,CLEC4E,CUL1,CYLD,DAB2IP,DMBT1,ESR1,FADD,FBXW11,GBP5,HAVCR2,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LGR4,LTF,MALT1,NLRC5,NRAS,OTULIN,PAK1,PAK2,PAK3,PELI1,PGLYRP2,PIK3C3,POLR3C,POLR3F,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PUM2,RPS19,SEC14L1,TAB2,TAB3,TANK,TBK1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,VAV1,XIAP 57.13 0.00879 0.156635464895636 GO:0006487 protein N-linked glycosylation biological_process 88 27 CCDC126,DAD1,DDOST,DPAGT1,EDEM3,ENGASE,FUT8,FUT9,GNPTG,GORASP1,MAN1C1,MAN2A1,MCFD2,MGAT4A,MGAT4B,MGAT4C,OSTC,PGM3,RPN2,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,TMEM165,UBE2G2,UGGT2 17.28 0.00884 0.157228106060606 GO:0006355 regulation of transcription, DNA-templat... biological_process 3494 736 ABCA2,ABLIM3,ACAD8,ACOD1,ACTL6A,ADCYAP1,ADNP,AEBP1,AFF3,AGO1,AGO2,AHCTF1,AHR,AKNA,AKT1,ANKRD49,ANP32A,ANXA4,APBB1,APBB2,ARGLU1,ARHGEF2,ARID1B,ARID2,ARID4A,ASH1L,ASXL3,ATF2,ATF4,ATF7IP,ATF7IP2,ATMIN,ATOH8,ATP2B4,ATRX,ATXN3,ATXN7,AURKB,BAHCC1,BANP,BATF2,BAZ1A,BAZ2A,BBX,BCAS3,BCLAF1,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BTK,BUD31,C14orf166,C1D,C1QBP,C3orf33,CAMK2A,CAMTA1,CAND1,CARF,CASK,CBX5,CCDC59,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH1,CDH13,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CELSR2,CENPU,CEP290,CFLAR,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIART,CIR1,CLU,CNOT2,CNOT7,CNOT8,COMMD2,COMMD4,COPS2,CPEB3,CPNE1,CREB5,CREM,CRYM,CSDE1,CSNK2A1,CSNK2A2,CSRNP3,CTBP1,CTDSPL2,CTNND1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK3,DCAF6,DDR2,DDX1,DDX20,DDX39B,DENND4A,DEPDC1,DHFR,DICER1,DMRT2,DMRTA1,DMTF1,DNTTIP2,DOT1L,DPF1,DPPA4,DR1,E2F5,E2F7,EAF2,EAPP,EBF4,EDRF1,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,ELP6,EMSY,EMX1,EN1,ENY2,ERC1,ERN2,ESF1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EYA3,EYA4,EZH2,FADD,FADS1,FAM200B,FAM208A,FAM58A,FANCA,FANCD2,FBN1,FBXW11,FGFR1,FKBP8,FLII,FOXJ1,FOXN3,FOXN4,FOXR1,FRYL,FUBP1,FZD6,GABPB1,GATAD2A,GATAD2B,GCLC,GDF9,GLI1,GLRX2,GPBP1,GPBP1L1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFV,H2AFY,HACE1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELLS,HESX1,HEXB,HEYL,HIPK3,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPD,HNRNPK,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSPA8,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INO80C,INO80D,INO80E,IRAK1,IRF2,IRF5,IRX4,ITGA6,ITGB1BP1,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANK1,KANK2,KAT2B,KAT6A,KAT7,KDM1B,KDM7A,KHDRBS3,KLF16,KLF6,KMT2A,KMT2D,KMT2E,KRAS,KRBOX4,L3MBTL1,L3MBTL3,LANCL2,LBX1,LCORL,LEO1,LGR4,LHX6,LHX9,LIF,LIMD1,LIN54,LITAF,LMO2,LMO3,LPIN1,LRP6,LRPPRC,LRRFIP2,LTF,LYL1,MAFK,MAGED1,MALT1,MAP2K3,MAP2K5,MAP3K2,MAPK8,MBD3,MBTD1,MBTPS2,MCTS1,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MGA,MIER1,MLF1,MLX,MLXIP,MNAT1,MORF4L1,MOSPD1,MSX2,MTA1,MTA3,MTDH,MTF2,MTOR,MXD3,MYB,MYF6,MYNN,MYSM1,NAA16,NAB1,NACA,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIF3L1,NIPBL,NKRF,NKX1-1,NLRC5,NLRP12,NPAS3,NR2C1,NR3C1,NR3C2,NTRK3,NUCKS1,NUP107,NUP35,OGT,ONECUT2,OTULIN,PARP10,PARP14,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBD1,PCBP3,PCGF3,PDE2A,PDE8A,PELI1,PFDN1,PHF1,PHF11,PHF12,PHF14,PHF20,PHF20L1,PHF21A,PHF21B,PHF6,PHIP,PHTF2,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLA2G10,PLCB1,PLK3,PNRC2,POFUT1,POLA1,POLR2K,POLR3C,POLR3F,POU2F2,PPHLN1,PPIE,PPP1R12A,PPP1R8,PPP2R1A,PRDM16,PREB,PRICKLE1,PRKCZ,PRMT1,PRMT3,PRMT5,PRRX1,PSIP1,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTOV1,PTPRK,PTPRN,PURA,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM39,RBMX,RBPJ,RBPMS,RECQL5,RELN,RFX2,RFX5,RFX7,RGMA,RGS14,RLF,RNF14,RNF2,RNF25,RNF4,RNF44,RNF6,RNF8,RORC,RPL6,RPS6KA1,RRP8,RUNX1T1,RXRA,RYR2,SAP18,SAP25,SAP30BP,SBNO1,SCAI,SCAP,SEMA4D,SENP2,SF1,SFPQ,SGK1,SIM1,SIM2 686.01 0.00907 0.16101393194707 GO:0034067 protein localization to Golgi apparatus biological_process 34 13 ARFRP1,ARL1,ATP9B,GAK,GCC2,GOLGA4,NRAS,PAQR3,RGPD1,RGPD5,SORL1,VPS13A,VPS13C 6.68 0.00923 0.163237156308851 GO:0051293 establishment of spindle localization biological_process 34 13 ARHGEF2,CENPA,CLASP1,FMN2,LLGL2,MYH9,NDE1,NUSAP1,PAFAH1B1,SPAG5,SPDL1,SPRY1,WDR43 6.68 0.00923 0.163237156308851 GO:0051651 maintenance of location in cell biological_process 151 42 AKT1,ANK3,ARL2BP,AURKB,BICD1,CAMSAP3,CDC42,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,DAG1,DCTN1,ECT2,EPB41L3,FAF1,FAM175B,FGFR1OP,GCC2,GET4,GSN,KDELR2,NLRP12,PCM1,RACGAP1,SEH1L,SGO1,SIRT2,SORL1,SPAG5,SPTBN4,SRI,SYNE1,TEX14,TLN1,TRIP6,TWF1,UVRAG,VPS13A,VPS13C,ZNF207 29.65 0.00925 0.163283364661654 GO:0051648 vesicle localization biological_process 225 59 AP1M2,AP3M2,AP3S1,ARF1,ARL6,BBS2,BET1,BRAF,BTBD9,CADPS2,CLASP1,CLASP2,CLN3,CNIH1,CNIH2,CPLX2,CUL3,DCTN1,DCTN2,EEA1,FNBP1L,GORASP1,HAP1,KIF13A,KIF23,MAP4K2,MCFD2,MLPH,NDE1,NLGN3,PAFAH1B1,PFN2,PIP5K1C,PPP6R3,PREB,PRKCZ,PTEN,RAB1A,RAB27B,RAB5A,RAP1A,RAP1B,RIMS1,SCFD1,SEC24A,SEC24B,SEC24D,SEC31A,SEPT5,SNAP23,SNAPIN,STX5,SYT1,SYT5,TGFA,TMED2,TPGS1,WDR43,YKT6 44.18 0.00936 0.16491512195122 GO:2001236 regulation of extrinsic apoptotic signal... biological_process 109 32 AKT1,BAX,BCL2,BIRC6,CFLAR,CTNNA1,CYLD,DAPK3,EYA3,EYA4,FADD,FAS,FGFR1,GCLC,GCLM,GSTP1,IL1B,ITGA6,ITGAV,ITM2C,MADD,MAP2K5,NF1,PAK2,PHIP,PPP2R1A,PSME3,RBCK1,RPS6KB1,TGFBR1,TNFSF12,WWOX 21.4 0.00948 0.165509889502762 GO:0070266 necroptotic process biological_process 27 11 ARHGEF2,BIRC3,CD14,CFLAR,CYLD,DNM1L,FADD,RBCK1,SIRT2,TRPM7,YBX3 5.3 0.00949 0.165509889502762 GO:0007288 sperm axoneme assembly biological_process 8 5 BBS2,IQCG,SPAG16,TPGS1,UBE2B 1.57 0.00957 0.165509889502762 GO:0017182 peptidyl-diphthamide metabolic process biological_process 8 5 DNAJC24,DPH1,DPH2,DPH3,DPH5 1.57 0.00957 0.165509889502762 GO:0017183 peptidyl-diphthamide biosynthetic proces... biological_process 8 5 DNAJC24,DPH1,DPH2,DPH3,DPH5 1.57 0.00957 0.165509889502762 GO:0032261 purine nucleotide salvage biological_process 8 5 ADA,ADK,AMPD3,APRT,HPRT1 1.57 0.00957 0.165509889502762 GO:0048681 negative regulation of axon regeneration biological_process 8 5 CERS2,EPHA4,KLK8,PTEN,RGMA 1.57 0.00957 0.165509889502762 GO:0060546 negative regulation of necroptotic proce... biological_process 8 5 ARHGEF2,BIRC3,FADD,RBCK1,YBX3 1.57 0.00957 0.165509889502762 GO:0070571 negative regulation of neuron projection... biological_process 8 5 CERS2,EPHA4,KLK8,PTEN,RGMA 1.57 0.00957 0.165509889502762 GO:2000574 regulation of microtubule motor activity biological_process 8 5 CFAP100,CFAP73,NDE1,PAFAH1B1,WDR43 1.57 0.00957 0.165509889502762 GO:0046931 pore complex assembly biological_process 17 8 AHCTF1,ANO6,CCT3,NDC1,NUP107,NUP205,NUP98,RTN4 3.34 0.00973 0.167967702205882 GO:0061008 hepaticobiliary system development biological_process 126 36 ACAT1,ADA,ASNS,AURKA,COBL,CPS1,CUL3,DDX39B,E2F7,EGFR,EZH2,GLI1,HMGCS1,HNRNPD,IGF2R,ITGA2,KRAS,LIMS2,MAN2A1,MKS1,NF1,NIPBL,ONECUT2,PIK3CA,PRMT5,QDPR,RAP1A,RGN,RPL32,RPS6KA1,SEC63,SP3,SRSF5,TGFB1,TYMS,UGT1A1 24.74 0.00981 0.169038 GO:0090407 organophosphate biosynthetic process biological_process 610 143 ABHD3,ACACA,ACAT1,ADA,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADK,ADNP,AK2,AK6,AKAP12,AKR1A1,ALOX15,AMDHD2,AMPD3,APLP1,APRT,ARF1,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CALM1,CDS2,CMPK1,COASY,CPNE1,CPNE3,CPS1,CRLS1,DCTD,DCXR,DGKA,DHFR,DTYMK,ENTPD8,ETNK1,FABP5,FADS1,FAR1,FGF5,FGFR1,FLAD1,FRS2,GABBR1,GARS,GART,GBAS,GGPS1,GIPR,GMPS,GNPAT,GNPDA2,GRM7,GRM8,GUK1,HEXB,HPRT1,HTR2B,IMPDH1,LPCAT3,LPCAT4,LPGAT1,LPIN1,MOCS1,MPPE1,MT-ATP6,MTHFD1,MTHFD2L,MTMR1,MTMR7,NADK,NADSYN1,NAGK,NF1,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NOS3,OCRL,OPRM1,PANK1,PANK3,PANK4,PCYT1A,PDE2A,PDXK,PDZD3,PGAP1,PGAP3,PGM3,PIGA,PIGN,PIGQ,PIGT,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIP5K1A,PIP5K1C,PLA2G10,PLA2G4B,PLA2G5,PLD1,PPCDC,PPIP5K1,PPIP5K2,PTDSS1,PTEN,PTH1R,PTK2B,RRM2B,SACM1L,SGMS1,SH3YL1,SLC25A13,SLC44A4,SUCLG1,SURF1,TAZ,TBPL1,TGFB1,TK1,TLR9,TPI1,TSHR,TYMS,UGDH,UGP2,UPRT 119.77 0.01015 0.173477381818182 GO:1901069 guanosine-containing compound catabolic ... biological_process 893 203 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPH,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ATL2,BCAS3,BMS1,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DNM3,DOCK4,DOCK7,ECT2,EGF,EGFR,EIF2S3,EIF5B,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GBP5,GCGR,GDI2,GFRA2,GMIP,GNA12,GNA14,GNGT1,GNL2,GPSM1,GSK3B,GTPBP10,HACD3,HPRT1,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,MFN1,MMAA,MSTO1,MTG1,MTIF2,MTOR,NCK1,NF1,NPRL3,NTRK2,OCRL,OPA1,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB30,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RABL2A,RAC2,RACGAP1,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOF,RHOT1,RIC1,RIC8B,RIMS1,RIT1,RP2,RPGR,RRAGB,RRAS2,RUNDC1,SBF1,SEMA4D,SEPT4,SEPT5,SEPT9,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TMED2,TNK2,TRIO,TRIP10,TUBB8,USP6NL,VAV1,WNT11 175.33 0.01015 0.173477381818182 GO:0009452 7-methylguanosine RNA capping biological_process 38 14 CDK7,CMTR2,GTF2H2,GTF2H3,GTF2H5,METTL1,MNAT1,NCBP2,NCBP3,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K 7.46 0.01016 0.173477381818182 GO:0036260 RNA capping biological_process 38 14 CDK7,CMTR2,GTF2H2,GTF2H3,GTF2H5,METTL1,MNAT1,NCBP2,NCBP3,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K 7.46 0.01016 0.173477381818182 GO:0045839 negative regulation of mitotic nuclear d... biological_process 38 14 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,MTBP,NME6,PSMG2,TEX14,TOM1L1,TTK,XRCC3,ZNF207 7.46 0.01016 0.173477381818182 GO:0006360 transcription from RNA polymerase I prom... biological_process 57 19 ATF4,CDK7,GTF2H2,GTF2H3,GTF2H5,H2AFY,HEATR1,MNAT1,MTOR,POLR1D,POLR2E,POLR2H,POLR2K,TAF1A,TAF1B,TAF1C,TAF1D,TTF1,UBTF 11.19 0.01027 0.174720235507246 GO:0043462 regulation of ATPase activity biological_process 57 19 AHSA2,ATP1B1,CHTOP,DNAJB11,DNAJC1,DNAJC10,DNAJC24,HNRNPU,LTF,METTL21A,PFN2,RGN,RYR2,SUMO1,TLR9,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2 11.19 0.01027 0.174720235507246 GO:0032989 cellular component morphogenesis biological_process 1257 279 ABI1,ABLIM3,ACTG1,ACTN1,ACTR2,ADIPOR1,ADNP,AGFG1,AKIP1,ANK2,ANK3,ANTXR1,ANXA7,APBB1,APBB2,ARHGAP4,ARHGEF1,ARHGEF2,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BAX,BBS1,BBS2,BCL2,BMPR1B,BOC,BRAF,BRWD3,C1QBP,CACNA1A,CAMK2A,CAPRIN1,CCDC114,CD9,CDC42,CDC42EP3,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CFLAR,CHL1,CHN1,CHRNA3,CLASP1,CLASP2,CLU,COBL,CRTAC1,CSF1R,CSNK1G1,CTNNA1,CUL3,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DAPK3,DCC,DHFR,DICER1,DNAI1,DNAI2,DNM1L,DNM3,DOCK7,DRC1,ECT2,EGFR,ENPP2,EPB41L3,EPHA4,EPHB2,ETV1,EVL,EZH2,FAM161A,FARP1,FBF1,FBLIM1,FES,FEZ1,FEZ2,FGD3,FGD4,FGD6,FHOD3,FMN1,FMNL2,FNBP1L,FOXJ1,FRMD6,FRY,FRYL,GALNT11,GNA12,GNPAT,GOLGA4,GORASP1,GPC1,GPM6A,GRHL2,GSK3B,GSN,HDAC2,HDAC6,HEXB,HEYL,HMGA2,HPRT1,HSPB11,IFRD1,IQCB1,IQCG,ITGA7,ITGAV,ITGB1BP1,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LARP4,LGI1,LHX9,LIF,LIMD1,LIMK1,LINGO3,LRP6,MAP1S,MAP2,MAP6,MAPK8IP3,MEF2A,MEF2C,METRN,MFF,MINK1,MKLN1,MKS1,MSX2,MYH10,MYH9,MYO10,MYOC,MYOZ3,NECTIN1,NLGN3,NME5,NOX4,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,ONECUT2,PAFAH1B1,PAK1,PAK3,PALLD,PAX2,PAX3,PCM1,PDGFRB,PEAK1,PHIP,PHLDB1,PLA2G10,PLOD3,PLXNA1,PLXNB1,PLXNC1,PLXND1,PNPT1,POC1B,PRPF40A,PRRX1,PTEN,PTK2,PTK2B,PTPN6,PTPRA,RAB1A,RADIL,RAPGEF2,RAPH1,RBPJ,RELN,RFX2,RGMA,RNF6,ROBO1,ROBO3,RP2,RPGR,RSPH9,RTN4,RTN4RL2,RUFY3,SART3,SCFD1,SDCBP,SDHAF2,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SGK1,SHTN1,SIDT2,SKIL,SLC11A2,SLC1A3,SMAD2,SMAD4,SNX2,SOS1,SOX6,SPAG16,SPINT2,SPTB,SPTBN1,SPTBN4,SS18,SSBP1,SSX2IP,STK25,STRAP,STRC,SZT2,TAPT1,TBPL1,TGFB1,TGFB1I1,TGFBR1,THY1,TLR9,TMEM237,TMEM67,TOP2B,TPGS1,TRIOBP,TROVE2,TTC21B,UBE2B,ULK2,UNK,USP33,USP9X,VEGFA,VIL1,WEE1,WNT11,WWTR1,ZMYM2,ZNF135,ZNF280D,ZNF385A 246.8 0.01029 0.174743924050633 GO:0006508 proteolysis biological_process 1654 361 ABTB1,ACE,ADAM10,ADAM22,ADAM23,ADAM28,ADAM33,ADAMDEC1,ADAMTS10,ADAMTS6,ADAMTSL1,ADAMTSL3,ADGB,AEBP1,AGBL1,AGTPBP1,AKT1,ALG13,AMER1,AMZ2,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,APH1A,ARIH1,ATG4B,ATP23,ATXN3,ATXN7,AURKA,AURKB,BAP1,BAX,BIRC3,BIRC6,BIRC7,BOK,BTBD2,BTBD9,BUB1B,C19orf68,C1QBP,C1RL,C1S,C2,C4A,C4B,C5AR2,CACUL1,CAPN13,CAPN8,CARD16,CASP4,CASP8,CD44,CD46,CDC23,CDC27,CDC6,CDK5RAP3,CFLAR,CHFR,CLN3,CLN8,CLU,CNDP2,COL4A3,COLEC11,COPS2,COPS3,CPA2,CPA5,CPA6,CPNE1,CPQ,CPS1,CR1,CRBN,CRYAB,CSNK2A1,CSNK2A2,CSTL1,CTRB1,CUL1,CUL3,CUL4B,CUL9,CYLD,DAB2IP,DAG1,DAPK1,DDB1,DESI2,DIABLO,DLD,DMWD,DNAJC1,DNAJC10,DPEP2,DPEP3,DPP10,DPP3,DYNC1LI1,EDEM3,EGF,EIF3F,ENY2,ERAP2,FADD,FAF1,FAM175B,FAM76B,FAS,FBXL3,FBXL4,FBXO11,FBXO22,FBXO7,FBXW11,FZR1,GCLC,GEN1,GGH,GGT1,GNA12,GPC3,GSAP,GSK3B,GSN,GZMK,HACE1,HDAC2,HDAC6,HERC5,HSP90B1,HSPD1,IL1B,IL1R2,IMMP2L,INPP5B,JKAMP,KCTD10,KEL,KLHL20,KLHL3,KLHL40,KLHL7,KLK11,KLK12,KLK8,LCMT1,LDLRAD3,LMLN,LNPEP,LNX1,LONRF1,LTA4H,LTF,MAEA,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MARCH6,MBTPS2,MDM2,METAP2,MME,MMP19,MMP28,MTA1,MTCH1,MYH9,MYSM1,N4BP1,NEDD4L,NFE2L2,NLRP12,NPLOC4,NRDC,NSMCE2,NUB1,OGT,OMA1,OTUD4,OVOS2,PAK2,PAX2,PBK,PCBP2,PCNP,PCOLCE2,PCSK5,PCSK7,PCYOX1,PDCD2,PDCD5,PDCL3,PGPEP1,PIAS1,PIK3C3,PLK3,PMPCB,POMT2,POR,PPP2R5C,PREP,PREPL,PRICKLE1,PRSS2,PRSS36,PRSS50,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTEN,PTK2,PTK2B,RBBP6,RBCK1,RBMX,RCHY1,RELN,RHBDD1,RHBDD2,RHBDL3,RNF121,RNF138,RNF14,RNF166,RNF216,RNF4,RNF43,RNF44,RNF6,RNF8,ROBO1,RPS6KA1,SCRN3,SDCBP,SEC11C,SEC61B,SENP2,SENP3-EIF4A1,SENP6,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SHFM1,SHMT2,SIRT2,SNX9,SPG7,SPINT2,SPOCK3,SPPL2A,SRI,STAMBP,SUMO1,SUMO2,SUSD4,TAF2,TANK,TASP1,TBL1XR1,TCEB1,TEX14,TFPI,TGFB1,TGFB1I1,THOP1,TLK2,TMEM67,TNFRSF10B,TOM1L1,TP63,TRADD,TRAPPC12,TRIM38,TRIP12,TRPC4AP,TTC3,TTK,UBA3,UBA52,UBA6,UBE2B,UBE2E1,UBE2G1,UBE2G2,UBE2J2,UBE2W,UBE2Z,UBE3A,UBE3C,UBE4A,UBR4,UBXN11,UBXN2B,UBXN4,UCHL5,UFL1,UGGT2,UQCRC2,USP12,USP15,USP17L17,USP17L3,USP24,USP25,USP3,USP32,USP33,USP34,USP36,USP39,USP4,USP7,USP8,USP9X,USPL1,VCPIP1,VEGFA,VIL1,VPS36,VPS4A,WAC,WDR20,WFDC2,WNT10B,WWP1,WWTR1,XIAP,XPNPEP3,XRCC3,ZC3H12A,ZNF207 324.75 0.01040 0.17601802513465 GO:0035567 non-canonical Wnt signaling pathway biological_process 152 42 AGO1,AGO2,ANKRD6,CALM1,CAMK2A,CDC42,CELSR1,CELSR2,CLTC,DAAM1,FZD6,GPC3,MKS1,MYOC,NFATC1,NKD1,PDE6B,PLCB1,PLCB2,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,UBA52,WNT11 29.84 0.01041 0.17601802513465 GO:0032366 intracellular sterol transport biological_process 14 7 ABCA2,CES1,LDLRAP1,LRP6,STAR,STARD4,VPS4A 2.75 0.01044 0.17601802513465 GO:2001241 positive regulation of extrinsic apoptot... biological_process 14 7 BAX,CTNNA1,DAPK3,FAS,NF1,PPP2R1A,WWOX 2.75 0.01044 0.17601802513465 GO:0007044 cell-substrate junction assembly biological_process 85 26 ACTN1,ARHGAP6,BCAS3,BCL2,CLASP1,CLASP2,COL17A1,DAPK3,FMN1,ITGA2,ITGA6,ITGB1BP1,ITGB4,KRT5,LAMC2,MYOC,PIP5K1A,PTEN,PTK2,PTK2B,PTPRK,THY1,TLN1,TNS1,TRIP6,VEGFA 16.69 0.01050 0.176497517730496 GO:0031345 negative regulation of cell projection o... biological_process 135 38 ARHGAP4,ARHGEF1,CERS2,DCC,DNM3,EPHA4,EPHB2,EVL,FKBP4,GAK,GORASP1,GSK3B,HDAC2,IFRD1,ITM2C,KANK1,KLK8,MDM2,NLGN3,PAFAH1B1,PAQR3,PFN2,PTEN,PTK2,RAP1GAP2,RAPGEF2,RGMA,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SNAPIN,THY1,ULK2 26.51 0.01051 0.176497517730496 GO:0051650 establishment of vesicle localization biological_process 213 56 AP1M2,AP3M2,AP3S1,ARF1,ARL6,BBS2,BET1,BRAF,BTBD9,CADPS2,CLASP1,CLASP2,CLN3,CNIH1,CNIH2,CPLX2,CUL3,DCTN1,DCTN2,EEA1,FNBP1L,GORASP1,HAP1,KIF13A,KIF23,MAP4K2,MCFD2,MLPH,NDE1,PAFAH1B1,PFN2,PIP5K1C,PPP6R3,PREB,PRKCZ,RAB1A,RAB27B,RAB5A,RAP1A,RAP1B,RIMS1,SCFD1,SEC24A,SEC24B,SEC24D,SEC31A,SEPT5,SNAP23,SNAPIN,STX5,SYT1,SYT5,TGFA,TMED2,WDR43,YKT6 41.82 0.01053 0.176497517730496 GO:0072331 signal transduction by p53 class mediato... biological_process 244 63 AKT1,ATR,ATRX,AURKA,AURKB,BANP,BAX,BOK,BRCA1,BRD7,BRIP1,CD44,CD74,CDK5RAP3,CENPJ,CHD3,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DNA2,DYRK2,E2F7,EHMT1,EHMT2,HDAC1,HDAC2,HUS1,KAT6A,L3MBTL1,MAPKAPK5,MBD3,MDM2,MDM4,MEAF6,PCBP4,PHF20,PIN1,PLK3,PRMT1,PRMT5,PTTG1IP,RAD17,RBBP4,RBBP7,RBBP8,RFC2,RFC4,RMI1,RPA3,RPS6KA6,RRP8,SENP2,SMYD2,TAF2,TOPBP1,TP63,UBA52,WRN,WWOX,ZMAT4,ZNF385A 47.91 0.01056 0.176497517730496 GO:0016311 dephosphorylation biological_process 462 111 ACP1,ADORA1,ALPL,ALPP,ANKLE2,ARPP19,BAG4,BCL2,BMP2K,BPNT1,CABIN1,CALM1,CAMK2G,CAMSAP3,CD2BP2,CDC14B,CDCA2,CDK5RAP3,CDKN3,CEP192,CNST,CSRNP3,CTDNEP1,CTDSPL2,CTTNBP2NL,DLG2,DLG3,DMPK,DUSP13,DUSP16,DUSP9,EIF2AK2,ENOPH1,EYA3,EYA4,FARP1,FBXW11,FRS2,HDHD2,HSP90B1,INPP1,INPP5A,INPP5B,ITGA2,LPIN1,MASTL,MEF2C,MPHOSPH10,MTMR1,MTMR7,NCK1,NT5C2,NT5C3B,NT5DC1,NTPCR,OCRL,PDGFRB,PFKFB1,PIN1,PLPP5,PLPPR2,PNKP,POLB,PON1,PPIP5K1,PPIP5K2,PPM1B,PPM1M,PPP1CB,PPP1CC,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP4R3B,PPP6R3,PPTC7,PTEN,PTP4A2,PTPN13,PTPN2,PTPN20,PTPN6,PTPRA,PTPRK,PTPRN,PTPRT,PXYLP1,RGN,SACM1L,SBF1,SDHAF2,SEMA4D,SMG6,SYTL2,TGFB1,TIGAR,TIMM50,TNS2,UBLCP1 90.71 0.01058 0.176497517730496 GO:0010763 positive regulation of fibroblast migrat... biological_process 11 6 AKT1,BAG4,DDR2,PAK3,TGFB1,UTS2 2.16 0.01060 0.176497517730496 GO:0051292 nuclear pore complex assembly biological_process 11 6 AHCTF1,NDC1,NUP107,NUP205,NUP98,RTN4 2.16 0.01060 0.176497517730496 GO:0006903 vesicle targeting biological_process 77 24 AP1M2,BET1,CLASP1,CLASP2,CNIH1,CNIH2,CUL3,GORASP1,MAP4K2,MCFD2,PPP6R3,PREB,RAB1A,SCFD1,SEC24A,SEC24B,SEC24D,SEC31A,SEPT5,SNAP23,STX5,TGFA,TMED2,YKT6 15.12 0.01066 0.177035282685512 GO:0007041 lysosomal transport biological_process 69 22 AKTIP,AP1G1,CHMP5,GAK,GCC2,GNPTG,HGS,HGSNAT,HOOK1,KIF13A,M6PR,MGRN1,NAGPA,SCYL2,SNAPIN,SNX16,SORL1,STX8,TRAK1,VPS11,VPS54,ZFYVE16 13.55 0.01067 0.177035282685512 GO:0001738 morphogenesis of a polarized epithelium biological_process 131 37 ANKRD6,CDC42,CELSR1,CELSR2,CLTC,DAAM1,DLG3,FZD6,GPC3,MKS1,NKD1,PAFAH1B1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SEC24B,TP63,UBA52,WNT11 25.72 0.01084 0.179538694885362 GO:0022616 DNA strand elongation biological_process 31 12 DNA2,LIG3,LIG4,NUCKS1,PARP2,POLA1,POLA2,POLD3,POLD4,POT1,PRIM1,RFC4 6.09 0.01092 0.179911789473684 GO:0031055 chromatin remodeling at centromere biological_process 31 12 CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,HELLS,ITGB3BP,MIS18BP1,RBBP4,RBBP7,SMARCA5 6.09 0.01092 0.179911789473684 GO:0051985 negative regulation of chromosome segreg... biological_process 31 12 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,WAPL,XRCC3,ZNF207 6.09 0.01092 0.179911789473684 GO:0006271 DNA strand elongation involved in DNA re... biological_process 24 10 DNA2,LIG3,LIG4,PARP2,POLA1,POLA2,POLD3,POLD4,PRIM1,RFC4 4.71 0.01103 0.181088688811189 GO:0006297 nucleotide-excision repair, DNA gap fill... biological_process 24 10 LIG3,LIG4,POLB,POLD3,POLD4,POLK,RFC2,RFC4,RPA3,UBA52 4.71 0.01103 0.181088688811189 GO:0072594 establishment of protein localization to... biological_process 542 128 AIP,AKT1,ATP9B,BAX,BCL2,CASP8,CDH1,CEP57,CSE1L,CYLD,DAB2IP,DAG1,DYRK2,ECT2,EGF,EGFR,FAF1,FBXO7,FBXW11,FYB,GAK,GCC2,GNPTG,GOLGA4,GSK3B,H2AFY,HGS,IL1B,IMMP2L,IPO11,IPO8,IPO9,KANK1,LITAF,MAPK8,MFF,MTOR,MTX1,MTX2,MTX3,NAGPA,NCKIPSD,NF1,NLRP12,NMT1,NOP58,NRAS,NUP107,NUP155,NUP205,NUP35,NUP50,NUP54,NUP58,NUP98,PARP10,PDE2A,PEX16,PEX3,PEX5L,PIK3R2,POLA2,POT1,PPM1B,PRICKLE1,PTTG1IP,RAB3GAP2,RAE1,RANBP2,RANBP6,RBCK1,RBPMS,RGPD1,RGPD5,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,RYR2,SEC61B,SEC63,SIX3,SMAD4,SNX16,SORL1,SPRN,SPTBN1,SRI,SRP19,SSR3,TBC1D10C,TGFB1,TGFBR1,TIMM10B,TIMM23B,TIMM50,TLR7,TLR9,TNPO1,TOMM20,TP63,TRAPPC8,TRIP6,UBA52,VPS13A,VPS13C,VPS36,WWTR1,YWHAQ,YWHAZ,ZC3H12A,ZFYVE16 106.42 0.01139 0.186672757417103 GO:0007009 plasma membrane organization biological_process 236 61 AKT1,ANK2,ANK3,ANO6,ANXA2,APPL1,ARFRP1,ARHGEF16,ATP1B1,BAG4,BBS1,BBS2,BIN2,BLZF1,C2CD5,CACNB3,CDH1,CLASP2,CLU,CNST,DENND4C,DPP10,DYSF,EFR3A,EHD2,EPB41L3,FCHO2,FNBP1L,FYB,GAK,GCC2,GOLGA4,GOLGA7,KCNB1,KCNIP4,KIF13A,LDLRAP1,LRP6,LYPLA1,MYH10,NOX1,PACS2,PIP5K1A,PKDCC,PKP2,PLSCR4,PPIL2,PRKCZ,PTEN,RAPGEF2,SCN3B,SERP1,SGIP1,SNX9,SPTBN1,SPTBN4,SYTL2,TMED2,TMEFF2,VAMP4,VIL1 46.34 0.01144 0.187165574912892 GO:0006352 DNA-templated transcription, initiation biological_process 214 56 ATF7IP,BCLAF1,CAND1,CCNC,CDK7,CRCP,ESR1,ESRRB,ESRRG,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,KAT2B,MED13,MED14,MED16,MED23,MED24,MED30,MED31,MNAT1,NCOA6,NR2C1,NR3C1,NR3C2,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RBPJ,RORC,RXRA,SMARCA5,TAF1A,TAF1B,TAF1C,TAF1D,TAF2,TBPL1,TBPL2,TEAD1,THRAP3,TTF1,UBTF,WNT10B,WWTR1,ZNF451 42.02 0.01159 0.189289895652174 GO:0002764 immune response-regulating signaling pat... biological_process 496 118 ABI1,ACOD1,ACTG1,ACTR2,ADA,ARPC1A,ARPC1B,BCAR1,BCL2,BIRC3,BLK,BPIFB1,BTK,C1QBP,C5AR2,CACNB3,CALM1,CASP8,CD14,CD247,CD3G,CD79B,CDC42,CHUK,CLEC4E,CR1,CUL1,CYFIP1,CYLD,DAB2IP,DENND1B,DMBT1,ELF1,ESR1,FADD,FBXW11,FCGR1B,FYB,GCSAM,HAVCR2,HLA-DPB1,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LAT,LGR4,LIMK1,LTF,MALT1,MAP2K4,MAP2K7,MAPK8,MEF2C,MYO10,MYO1G,NCK1,NCKIPSD,NFATC1,NRAS,OTULIN,PAK1,PAK2,PAK3,PAWR,PDE4D,PELI1,PGLYRP2,PIGR,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTPN2,PTPN6,PUM2,RBCK1,SEC14L1,SOS1,TAB2,TAB3,TANK,TBK1,THY1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,VAV1,XIAP,ZAP70 97.38 0.01172 0.191080763888889 GO:0071900 regulation of protein serine/threonine k... biological_process 459 110 ACSL1,ADORA1,AKT1,ATP2B4,BCCIP,BIRC7,BRAF,CALM1,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC6,CDK12,CDK5RAP3,CDK7,CDKN3,CHORDC1,CHRNA7,CSF1R,DAB2IP,DNAJA1,DUSP16,DUSP9,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM58A,FBXO7,FGFR1,FRS2,GADD45G,GSTP1,H2AFY,HACD3,HERC5,HGS,HIPK3,HTR2B,IGF1R,IL1B,IRAK1,KAT2B,KRAS,LAMTOR3,LRP6,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MNAT1,MST1R,NEK10,NF1,NOX4,NTRK3,PAK1,PAK3,PAQR3,PDCD10,PDE5A,PDGFRB,PIK3CB,PIK3R5,PPP1R1B,PPP2R1A,PRKAR2A,PTEN,PTK2B,PTPN6,RALB,RAP1A,RAPGEF2,RGS14,RGS3,SASH1,SHC2,SORL1,SPAG9,SPDYA,SPRY1,TAB2,TAB3,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TRAF4,UBA52,UVRAG,VEGFA 90.12 0.01175 0.191237868284229 GO:0032268 regulation of cellular protein metabolic... biological_process 2299 492 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AGO1,AGO2,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ANKLE2,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARIH1,ARL2BP,ARPP19,ASH1L,ATF4,ATP2B4,ATRX,ATXN2,AURKA,BAG4,BAX,BCCIP,BCL2,BIRC3,BIRC6,BIRC7,BOK,BOLL,BRAF,BRCA1,BRD4,BRD7,BUB1B,C12orf65,C1QBP,C3orf33,C4A,C4B,C5AR2,CACUL1,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CCDC88A,CCDC88C,CCL25,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD44,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK12,CDK5RAP3,CDK7,CDKN3,CDON,CEP192,CHAD,CHFR,CHORDC1,CHRNA3,CHRNA7,CHTOP,CLN3,CLN8,CLU,CNOT2,CNST,CNTN1,COL4A3,CPEB1,CPEB3,CR1,CRYAB,CSF1R,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTR9,CUL1,CUL3,DAB2IP,DAG1,DAPK1,DAPK3,DCUN1D4,DDR2,DDX1,DDX39B,DDX6,DIABLO,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DOCK7,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF1,EIF2A,EIF2AK2,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELP4,ENPP2,EPHA4,EPRS,EZH2,FADD,FAF1,FAM150A,FAM58A,FANCI,FARP1,FAS,FBXO22,FBXO7,FBXW11,FGFR1,FGFR1OP,FNTA,FRS2,FXR1,FZR1,GADD45G,GCLC,GDF9,GEN1,GFRA2,GIGYF2,GMFB,GMFG,GNA12,GPC3,GPRC5B,GRB7,GSK3B,GSN,GSTP1,H2AFY,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC8,HERC5,HGS,HHATL,HIPK3,HNRNPD,HSP90B1,HSPD1,HSPH1,HTR2B,HUS1,IGF1R,IGF2BP3,IL15,IL1B,IL1R2,IL22RA2,IMPACT,IRAK1,ITGA2,ITGB1BP1,KAT2B,KLHL40,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LCMT1,LIF,LIMK1,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALSU1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARVELD3,MASTL,MDM2,MEF2C,METTL14,MINK1,MKNK1,MNAT1,MOB2,MPHOSPH10,MST1R,MTCH1,MTF2,MTG1,MTIF2,MTOR,MTRF1,MVP,MYB,MYOC,N4BP1,NCBP2,NCK1,NCOR1,NDRG2,NEK10,NF1,NGDN,NIPBL,NLRP12,NOX1,NOX4,NRDC,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,OGFOD1,OGT,OPRK1,OPRM1,OSBPL8,OVOS2,PABPC1,PAFAH1B1,PAIP2,PAK1,PAK2,PAK3,PAQR3,PARP10,PAX2,PAX7,PAXBP1,PBK,PCOLCE2,PDCD10,PDCD2,PDCD5,PDCL3,PDE4D,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PHIP,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PIWIL4,PLA2G10,PLA2G5,PLCB1,PLK3,PODN,POLDIP3,POLR2G,POR,PPP1R12A,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R3C,PPP2R5C,PPP2R5E,PPP6R3,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRMT3,PRMT5,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTCD3,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTTG1IP,PUM3,PURA,RAC2,RALB,RAP1A,RAP1B,RAPGEF2,RBM4,RBPMS,RCHY1,RELN,RELT,RGN,RGS14,RGS3,RHBDD1,RNF138,RNF14,RNF166,RNF4,ROBO1,ROS1,RPS5,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RTN4RL2,RXRA,SASH1,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SERP1,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SHC2,SIRT2,SMAD4,SMYD3,SNX9,SORBS3,SORL1,SPAG9,SPDYA,SPINT2,SPOCK3,SPRTN,SPRY1,SPTBN4,STAP2,STK25,STRAP,SUMO1,SUMO2,SYTL2,TAB2,TAB3,TANK,TARBP2,TBC1D10C,TBK1,TELO2,TEX14,TFPI,TGFA,TGFB1,TGFBR1,THY1,TIA1,TLK2,TLR7,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNK2,TOM1L1,TRADD,TRAF4,TRIM5,TRIP12,TTK,TWF1,TYMS,UBA52,UBE2B,UBE2E1,UBE3A,UCHL5,UFL1,UNK,USP4,UVRAG,VEGFA,VIL1,WAC,WFDC2,WNT10B,WNT11,WWTR1,XIAP,XRCC3,YBX3,YRDC,ZC3H12A,ZNF207,ZNF385A,ZNF451,ZNF706,ZP4 451.38 0.01208 0.196077603448276 GO:0031577 spindle checkpoint biological_process 35 13 AURKB,BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,SPDL1,TEX14,TTK,XRCC3,ZNF207 6.87 0.01210 0.196077603448276 GO:0030177 positive regulation of Wnt signaling pat... biological_process 149 41 AMER1,ANKRD6,ATP6V1C2,CSNK2A1,CTDNEP1,DAPK3,GPC3,GPRC5B,KANK1,LGR4,LGR5,LRP6,NKD1,PIN1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RBPJ,RNF220,TNKS,UBA52,USP34,WNT10B,XIAP 29.25 0.01211 0.196077603448276 GO:0048519 negative regulation of biological proces... biological_process 4419 919 AAAS,ABAT,ABCA5,ABCE1,ABI1,ABR,ACADVL,ACE,ACOD1,ACOT8,ACTN1,ADA,ADAM10,ADAM22,ADAMDEC1,ADCYAP1,ADIPOR1,ADIPOR2,ADNP,ADORA1,AEBP1,AGO1,AGO2,AHR,AIP,AIPL1,AKT1,ALOX15,AMBRA1,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANKLE2,ANKRD6,ANTXR1,ANXA2,ANXA4,ANXA7,APBB1,APBB2,APLP1,APOBEC3B,APOBEC3F,ARF1,ARHGAP4,ARHGAP6,ARHGEF1,ARHGEF15,ARHGEF2,ARID2,ARID4A,ARPP19,ASH1L,ASIC2,ASNS,ATAD1,ATF2,ATF4,ATF7IP,ATG3,ATOH8,ATP2B4,ATP5B,ATR,ATRAID,ATRX,ATXN2,ATXN7,AURKA,AURKB,AZIN2,BAG4,BAHCC1,BANP,BAP1,BAX,BAZ2A,BBS2,BCAS3,BCHE,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLK,BNIP2,BPIFB1,BPTF,BRAF,BRCA1,BRD7,BRINP1,BRINP2,BRIP1,BTBD10,BTG3,BTK,BUB1B,C16orf45,C1D,C1QBP,C3orf33,C4A,C4B,C5AR2,CABIN1,CACNA1A,CACNA1C,CALM1,CAMSAP3,CAND1,CAPRIN1,CAPZA1,CARD16,CARMIL2,CASK,CASP8,CBX5,CCNE2,CCNT1,CD14,CD200,CD2BP2,CD44,CD46,CD74,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC6,CDH1,CDH13,CDK5RAP3,CDK7,CDKN3,CEACAM5,CENPJ,CEP192,CEP63,CERS2,CFLAR,CHAD,CHCHD3,CHD7,CHFR,CHID1,CHL1,CHORDC1,CHRD,CHRNA7,CIART,CIR1,CLASP1,CLASP2,CLDN7,CLEC5A,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CNOT2,CNOT7,CNOT8,CNST,COL4A3,COPS2,CPEB1,CPEB3,CPNE1,CR1,CRBN,CREM,CRHBP,CRYAB,CRYM,CSF1R,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTC1,CTDSPL2,CTNNA1,CTNND1,CTR9,CTTNBP2NL,CUL1,CUL3,CUX1,CXCL12,CXCR2,CXXC4,CYLD,CYP19A1,DAB2IP,DAD1,DAG1,DAPK1,DAPK3,DAPL1,DCBLD2,DCC,DDB1,DDIAS,DDIT4L,DDR1,DDX20,DDX39B,DDX6,DEPDC1,DHRS2,DICER1,DLG2,DLG3,DNA2,DNAJA1,DNAJC1,DNAJC10,DNM3,DOT1L,DPH3,DPPA4,DR1,DROSHA,DTX1,DUSP16,DUSP9,DYNC1LI1,DYRK2,E2F7,EAF2,EAPP,EGF,EGFL7,EGFR,EHMT1,EHMT2,EI24,EIF2AK2,EIF4A2,EIF4E,EIF4G2,EIF6,ELF1,ELF3,ELP2,EML2,EN1,ENY2,EPHA4,EPHB2,EPRS,ERN2,ERO1A,ESR1,ETV6,ETV7,EVL,EXD1,EYA3,EYA4,EZH2,FADD,FAF1,FAM111A,FANCD2,FANCI,FARP1,FAS,FBN1,FBXO7,FBXW11,FGF12,FGFR1,FGFR1OP,FHL1,FHOD3,FIGNL1,FKBP4,FKBP6,FKBP8,FMN2,FOXJ1,FOXN3,FRY,FUOM,FXR1,FZD6,FZR1,GABBR1,GABRA5,GABRE,GAK,GATAD2A,GATAD2B,GBAS,GCLC,GCLM,GCSAM,GDF9,GEN1,GET4,GFRA2,GIGYF2,GIPR,GLA,GLI1,GMFB,GMFG,GMIP,GNG4,GORASP1,GPC1,GPC3,GPR35,GRB10,GRB7,GRHL2,GRID2IP,GRM7,GRM8,GSK3B,GSN,GSTP1,GTF2H2,GTF2I,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELB,HELLS,HERC5,HESX1,HEYL,HGS,HHATL,HIPK3,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HORMAD1,HOXA7,HOXA9,HSF4,HSP90B1,HSPA8,HSPD1,HTR2B,HUS1,HYAL1,IDO1,IFRD1,IGF1R,IGF2BP3,IGFBP2,IL15,IL18BP,IL1B,IL1R2,IL22RA2,IL2RA,IL4R,IMPACT,IP6K2,IPO8,IQCB1,IRAK1,IRF2,ITGA6,ITGAV,ITGB1BP1,ITGB8,ITM2C,ITPR1,JADE1,JAZF1,JUND,KANK1,KANK2,KAT2B,KAT6A,KCNB1,KEL,KLF16,KLHL20,KLHL40,KLK8,KMT2A,KMT2D,KMT2E,KNTC1,KRAS,KRIT1,KRT16,L3MBTL1,LAMTOR1,LAMTOR3,LANCL2,LBX1,LCMT1,LEO1,LGR4,LHX9,LIF,LIG3,LIG4,LIMD1,LIMK1,LIMS2,LITAF,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,LTA,LTBP1,LTF,LUC7L,LYPLA1,LZTS2,MAEA,MAGED1,MALSU1,MALT1,MAP2K4,MAP2K5,MAP3K12,MAP6D1,MAPK8,MAPKAPK5,MARCH5,MARVELD3,MASTL,MBD3,MDM1,MDM2,MDM4,MED14,MED21,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,METTL14,MGRN1,MIA3,MID1IP1,MIDN,MIER1,MLF1,MLX,MMP28,MMRN2,MNAT1,MORF4L1,MOSPD1,MPHOSPH10,MSX2,MTA3,MTBP,MTDH,MTF2,MTOR,MVP,MXD3,MYB,MYF6,MYO16,MYO18A,MYOC 867.62 0.01239 0.200265903614458 GO:0046794 transport of virus biological_process 74 23 AAAS,CHMP5,DDX39B,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,THOC1,THOC2,THOC7,UBA52,VTA1,XPO1 14.53 0.01269 0.204762525773196 GO:0006491 N-glycan processing biological_process 21 9 EDEM3,ENGASE,FUT8,GNPTG,MAN1C1,MAN2A1,MGAT4A,MGAT4B,MGAT4C 4.12 0.01273 0.204865308219178 GO:0032088 negative regulation of NF-kappaB transcr... biological_process 66 21 ACOD1,ANXA4,CDK5RAP3,CYLD,DAB2IP,FOXJ1,HAVCR2,IRAK1,MAP2K5,NFKBID,NLRC5,NLRP12,OTULIN,PARP10,PELI1,RBCK1,TAX1BP1,TLR9,UFL1,USP7,ZC3H12A 12.96 0.01274 0.204865308219178 GO:0031365 N-terminal protein amino acid modificati... biological_process 28 11 HHATL,KAT2B,MAP6D1,METAP2,NAA10,NAA16,NAA20,NAA25,NAA60,NMT1,PPM1B 5.5 0.01290 0.205996129032258 GO:0034080 CENP-A containing nucleosome assembly biological_process 28 11 CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,ITGB3BP,MIS18BP1,RBBP4,RBBP7,SMARCA5 5.5 0.01290 0.205996129032258 GO:0061641 CENP-A containing chromatin organization biological_process 28 11 CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,ITGB3BP,MIS18BP1,RBBP4,RBBP7,SMARCA5 5.5 0.01290 0.205996129032258 GO:0097421 liver regeneration biological_process 28 11 AURKA,EGFR,EZH2,GLI1,PRMT5,RAP1A,RGN,RPL32,SRSF5,TGFB1,TYMS 5.5 0.01290 0.205996129032258 GO:0022411 cellular component disassembly biological_process 442 106 AAAS,ABCE1,ACIN1,ADAM10,ARHGEF2,ARID2,ATG3,ATG4B,BLCAP,BOK,C12orf65,C16orf45,CAPZA1,CARMIL2,CASP8,CCNB2,CD44,CDH1,CDK5RAP3,CLASP1,CLASP2,CTDNEP1,CTRB1,DAP3,DCTN1,DDR1,DDR2,DICER1,DNM1L,ELN,ERN2,FBN1,FBXO7,FNTA,GAK,GSN,HDAC6,HSPA8,LAMC2,LCP1,LPIN1,MAP1S,MAP6D1,MCTS1,MID1IP1,MMP19,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTIF2,MTIF3,MTRF1,MTRF1L,NAPB,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OGFOD1,PAFAH1B1,PLK3,PRSS2,PTCD3,PTK2,RAE1,RANBP2,SEH1L,SMARCD1,SMARCD2,SMARCE1,SPATA18,SPTB,SPTBN1,SPTBN4,STMN4,STX5,TFIP11,TGFB1,TIGAR,TRIOBP,TWF1,VIL1,VPS4A,WDR45B 86.78 0.01292 0.205996129032258 GO:0010761 fibroblast migration biological_process 39 14 AKT1,ARHGAP4,BAG4,BRAF,DDR2,GNA12,ITGB1BP1,PAK3,PIP5K1A,PRR5L,SGPL1,TGFB1,TNS1,UTS2 7.66 0.01304 0.206855810810811 GO:0051496 positive regulation of stress fiber asse... biological_process 39 14 ARHGEF15,BAG4,BRAF,EVL,ITGB1BP1,LIMK1,MTOR,MYOC,NOX4,PAK1,PFN2,SORBS3,TGFBR1,WNT11 7.66 0.01304 0.206855810810811 GO:0051653 spindle localization biological_process 39 14 ACTR2,ARHGEF2,CENPA,CLASP1,FMN2,LLGL2,MYH9,NDE1,NUSAP1,PAFAH1B1,SPAG5,SPDL1,SPRY1,WDR43 7.66 0.01304 0.206855810810811 GO:0032543 mitochondrial translation biological_process 120 34 C12orf65,C1QBP,DAP3,DARS2,HARS,LRPPRC,MALSU1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTG1,MTIF2,MTIF3,MTRF1,MTRF1L,NDUFA7,NSUN4,PTCD3,RARS2 23.56 0.01348 0.213115622895623 GO:0006900 membrane budding biological_process 99 29 ANXA2,ARF1,BET1,CHMP5,CNIH1,CNIH2,CUL3,FCHO1,FCHO2,FNBP1L,GORASP1,HMP19,MCFD2,MIA3,MYO18A,PPP6R3,PREB,RAB1A,SCFD1,SEC24A,SEC24B,SEC24D,SEC31A,SNAP91,STX5,TGFA,TMED2,VPS4A,VTA1 19.44 0.01348 0.213115622895623 GO:0008645 hexose transport biological_process 150 41 AAAS,ADIPOR2,AKT1,APPL1,ARPP19,ASPSCR1,BRAF,C2CD5,FABP5,GPC3,GRB10,IL1B,M6PR,NDC1,NFE2L2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PIK3R2,PIK3R3,PRKCZ,RAE1,RANBP2,RAP1A,RPS6KB1,SEH1L,SIRT6,SLC25A27,SLC2A5,SLC2A9,SLC5A1,STXBP4,VIL1 29.45 0.01358 0.214335764705882 GO:0044763 single-organism cellular process biological_process 13212 2639 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABHD3,ABI1,ABI3,ABLIM2,ABLIM3,ABR,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOX3,ACOXL,ACSBG1,ACSF3,ACSL1,ACSM6,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ADA,ADAM10,ADAM22,ADAM23,ADAMDEC1,ADAMTSL1,ADCY10,ADCY4,ADCYAP1,ADD3,ADGRA3,ADGRD1,ADGRG2,ADGRG7,ADIPOR1,ADIPOR2,ADK,ADNP,ADORA1,ADPGK,ADPRHL1,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AHSA2,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP2,AKAP3,AKAP7,AKIP1,AKR1A1,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG9,ALKBH2,ALOX15,ALPL,AMBRA1,AMD1,AMDHD2,AMER1,AMER3,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKH,ANKLE2,ANKRD10,ANKRD49,ANKRD53,ANKRD6,ANLN,ANO10,ANO2,ANO6,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APLP1,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQP7,AQP8,AQR,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID2,ARID4A,ARL1,ARL2BP,ARL5C,ARL6,ARL8A,ARMC4,ARPC1A,ARPC1B,ARPP19,ARPP21,ARSA,ART3,ASAH1,ASB15,ASH1L,ASIC2,ASNS,ASPG,ASPSCR1,ASUN,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATG16L2,ATG3,ATG4B,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN10,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZI2,AZIN2,B3GALNT2,BAG4,BAHCC1,BAIAP3,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBS1,BBS2,BCAR1,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCL7C,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLCAP,BLK,BLNK,BLZF1,BMPR1B,BMS1,BNIP2,BOC,BOK,BOLL,BORA,BPIFB1,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD9,BTG3,BTK,BUB1B,BUD31,C11orf88,C12orf4,C12orf65,C16orf45,C16orf62,C16orf89,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,C3orf33,C3orf38,C5AR2,C6orf120,C9orf142,CA1,CA12,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAND1,CAPRIN1,CAPS,CAPZA1,CARD16,CARF,CARMIL2,CARS,CASK,CASKIN1,CASP4,CASP8,CATIP,CATSPER4,CCDC114,CCDC126,CCDC14,CCDC6,CCDC66,CCDC78,CCDC80,CCDC88A,CCDC88B,CCDC88C,CCL25,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CD14,CD160,CD200,CD22,CD247,CD3G,CD44,CD46,CD52,CD6,CD7,CD74,CD79B,CD81,CD82,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDH23,CDH26,CDH8,CDHR1,CDHR3,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CDON,CDS2,CEACAM5,CECR1,CELSR1,CELSR2,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP135,CEP164,CEP192,CEP290,CEP350,CEP57,CEP57L1,CEP63,CEP70,CEP89,CERS2,CES1,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CFLAR,CHAC2,CHAD,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHL1,CHMP3,CHMP5,CHMP6,CHN1,CHODL,CHORDC1,CHRAC1,CHRD,CHRM2,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHST1,CHTOP,CHUK,CIB2,CKMT2,CLASP1,CLASP2,CLCC1,CLCN1,CLCN3,CLCNKA,CLDN11,CLDN4,CLDN7,CLEC2D,CLEC4E,CLEC5A,CLIP1,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CMPK1,CMTM7,CNDP2,CNGA1,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,CNTN1,CNTN5,CNTNAP3,CNTNAP3B,COA1,COASY,COBL,COG2 2594.04 0.01362 0.214359782608696 GO:0051247 positive regulation of protein metabolic... biological_process 1419 311 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ANKLE2,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARIH1,ARL2BP,ATG4B,ATP2B4,AURKA,BAG4,BAX,BCL2,BIRC3,BIRC7,BOK,BOLL,BRAF,BRCA1,BRD7,BUB1B,C1QBP,C5AR2,CACUL1,CALM1,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CD44,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK5RAP3,CDON,CHFR,CHRNA3,CHRNA7,CHTOP,CLU,CNTN1,COL4A3,CPEB3,CR1,CSF1R,CSNK2A1,CSNK2A3,CTBP1,CTR9,CUL1,CUL3,CUL4B,CYBB,DAB2IP,DAPK1,DCUN1D4,DDR2,DDX39B,DIABLO,DOCK7,DUSP9,ECT2,EGF,EGFR,EIF2AK2,EIF6,ENPP2,EPHA4,EZH2,FADD,FAM150A,FAM58A,FANCI,FAS,FBXO22,FBXW11,FGFR1,FNTA,FRS2,FZR1,GADD45G,GCLC,GDF9,GGA1,GPC3,GPRC5B,GSK3B,GSN,HACD3,HAVCR2,HDAC1,HDAC2,HNRNPD,HNRNPK,HSPD1,HSPH1,HTR2B,IGF1R,IL15,IL1B,IMPACT,IRAK1,ITGA2,ITGB1BP1,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LIF,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MDM2,MEF2C,MINK1,MOB2,MST1R,MTCH1,MTF2,MTOR,MYB,NEDD4L,NEK10,NIPBL,NKD1,NLRP12,NOX1,NOX4,NRDC,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,OAZ1,OAZ2,OGT,OPRK1,OPRM1,OSBPL8,PABPC1,PAK1,PAK2,PAK3,PAWR,PAX7,PAXBP1,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PLA2G10,PLA2G5,PLCB1,PLK3,POLDIP3,POLR2G,PPP1R12A,PPP1R7,PPP2R3C,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTTG1IP,PXYLP1,RALB,RAP1A,RAP1B,RAPGEF2,RBPMS,RCHY1,RELN,RELT,RGN,RHBDD1,RNF138,RNF14,RNF166,ROBO1,RPS6KB1,RPS6KB2,RXRA,SASH1,SCAP,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SERP1,SHC2,SIRT2,SMAD4,SMYD3,SNX9,SORBS3,SORL1,SPAG9,SPDYA,SPRTN,STAP2,STK25,STX5,SUMO1,SUMO2,TAB2,TAB3,TANK,TARBP2,TBK1,TELO2,TGFA,TGFB1,TGFBR1,TIPARP,TLR1,TLR7,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNFSF12,TNK2,TOM1L1,TRADD,TRAF4,TRIM5,TTK,UBA52,UBE2E1,UBE3A,VEGFA,WNT11,XIAP,YBX3,ZC3H12A,ZP4 278.61 0.01363 0.214359782608696 GO:0016055 Wnt signaling pathway biological_process 466 111 AGO1,AGO2,AMER1,AMER3,ANKRD10,ANKRD6,ARL6,ATP6V1C2,BRD7,CALM1,CAMK2A,CCDC88C,CDC42,CELSR1,CELSR2,CLTC,CSNK1G1,CSNK2A1,CSNK2A2,CTDNEP1,CTNND1,CTR9,CUL1,CUL3,CXXC4,CYLD,DAAM1,DAB2IP,DAPK3,DDB1,EGF,FBXW11,FZD6,GLI1,GPC3,GPRC5B,GRB10,GRK6,GSK3B,HDAC1,IGFBP2,JADE1,KANK1,KDM6A,LEO1,LGR4,LGR5,LIMD1,LRP6,LRRFIP2,LZTS2,MARK1,MKS1,MYOC,NDRG2,NFATC1,NKD1,OTULIN,PDE6B,PIN1,PLCB1,PLCB2,PPP2R1A,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,RAB5A,RBPJ,RNF138,RNF220,RNF43,RYR2,SCYL2,SDHAF2,SENP2,SIX3,STRN,TBL1XR1,TCF7,TGFB1I1,TMEM237,TNKS,UBA52,UBE2B,USP34,VPS29,WNT10A,WNT10B,WNT11,WWOX,WWTR1,XIAP 91.49 0.01365 0.214359782608696 GO:0051345 positive regulation of hydrolase activit... biological_process 871 197 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AHSA2,AKT1,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ARL1,ATP1B1,BAX,BCAS3,BNIP2,BOK,CALM1,CAMK2A,CAMK2G,CASP8,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,COL4A3,CR1,CYTH4,DAB2IP,DAPK1,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DIABLO,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,ELMOD3,EPS8L1,ESR1,EZH2,FADD,FAM13B,FARP1,FARP2,FAS,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FNTA,FRS2,GCGR,GDI2,GFRA2,GMIP,GPIHBP1,GSK3B,GSN,HACD3,HNRNPU,HSPD1,HTR2B,IL2RA,INPP5B,ITGA2,ITGA6,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MAPK8,MCF2,MCF2L,MEF2C,MTCH1,NCK1,NF1,NLRP12,NPRL3,OCRL,P2RY12,PCOLCE2,PDCD2,PDCD5,PDGFRB,PFN2,PIK3R2,PIN1,PKP4,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,POT1,PPP1R12A,PREB,PRKCZ,PSD3,PSD4,PSME3,PSME4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,ROBO1,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,SSBP1,ST5,SUMO1,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TNFRSF10B,TNNT2,TOR1AIP1,TOR1AIP2,TRADD,TRIO,TRIP10,USP6NL,VAV1,VEGFA,WNT11,WRN 171.01 0.01374 0.215412921535893 GO:0051234 establishment of localization biological_process 4579 950 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABI1,ABR,ACACA,ACAP1,ACE,ACSL1,ACTG1,ACTN1,ACTR2,ADA,ADCYAP1,ADD3,ADIPOR2,ADORA1,ADPRHL1,AGFG1,AHCTF1,AHNAK,AIP,AKAP12,AKAP3,AKT1,AKTIP,ALOX15,AMPH,ANK2,ANK3,ANKH,ANKRD53,ANO10,ANO2,ANO6,ANP32A,ANXA2,ANXA4,ANXA6,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APLP1,APOO,APPL1,APRT,AQP7,AQP8,ARF1,ARFGAP2,ARFRP1,ARHGAP33,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL6,ARMC1,ARPC1A,ARPC1B,ARPP19,ASIC2,ASPSCR1,ATAD1,ATF4,ATG16L2,ATG3,ATG4B,ATL2,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATXN2,AZIN2,BAIAP3,BAX,BBS1,BBS2,BCAS3,BCL2,BET1,BICD1,BIN2,BLK,BLZF1,BOK,BRAF,BTBD9,BTF3,BTK,C12orf4,C14orf166,C16orf62,C1QTNF5,C2,C2CD5,C3orf49,C4A,C4B,C5AR2,CA1,CA12,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CADPS2,CALM1,CAMK2A,CAMK2G,CASK,CASP8,CATSPER4,CCDC91,CCZ1B,CD14,CD163,CD247,CD3G,CD6,CD74,CD81,CD9,CDC23,CDC42,CDH1,CDH13,CDH23,CENPA,CENPQ,CEP290,CEP57,CES1,CHD7,CHMP3,CHMP5,CHMP6,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHTOP,CLASP1,CLASP2,CLCC1,CLCN1,CLCN3,CLCNKA,CLEC4E,CLEC5A,CLN3,CLN8,CLTA,CLTC,CLU,CNGA1,CNIH1,CNIH2,CNNM1,CNST,CNTN1,COG2,COG5,COLEC11,COPA,COPB1,CORO7,COX17,COX5A,COX6A1,COX6B2,COX7A2L,CPLX2,CPNE1,CPNE3,CPT2,CRACR2A,CRBN,CRHBP,CROT,CRYAB,CRYM,CSE1L,CSF1R,CSNK1G1,CTDSPL2,CTTNBP2NL,CUL3,CUX1,CXADR,CXCL12,CXCR2,CYB561,CYBB,CYFIP1,CYLD,DAB2IP,DAG1,DAPK1,DBI,DCTN1,DCTN2,DCTN4,DCTN6,DDR1,DDX20,DDX39B,DENND1B,DENND4C,DLG3,DMBT1,DMPK,DNAJA1,DNAJC1,DNAJC13,DNM1L,DNM3,DPH3,DPP10,DSCR3,DUOXA1,DUSP16,DYNC1I2,DYNC1LI1,DYRK2,DYSF,ECT2,EEA1,EFR3A,EGF,EGFR,EHD2,EIF2S3,EIF4E,EIF6,ENPP2,ENY2,EPG5,ERC1,ERO1A,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,EXPH5,FABP5,FAF1,FAM21A,FBLN5,FBXO22,FBXO7,FBXW11,FCGR1B,FCHO1,FCHO2,FES,FEZ1,FGF12,FGFR1,FHL1,FIP1L1,FKBP4,FMN2,FNBP1,FNBP1L,FRAS1,FXYD1,FYB,GABRA5,GABRE,GABRG3,GABRP,GAK,GBP5,GCC2,GCGR,GCNT3,GDF9,GDI2,GET4,GGA1,GIF,GIPR,GJB1,GJC2,GLRA3,GLS,GLS2,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GPC3,GPIHBP1,GPM6A,GPR35,GPR89B,GRB10,GRIA4,GRID1,GRM7,GSK3B,GSN,GTF2H2,GUK1,H2AFY,HAP1,HDAC1,HDAC6,HDLBP,HGS,HGSNAT,HMP19,HNRNPA2B1,HNRNPA3,HNRNPK,HOMER3,HOOK1,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HTR2B,HVCN1,ICA1,ICE1,IGF2BP3,IGF2R,IL1B,IL1R2,IL4R,IMMP2L,IP6K2,IPO11,IPO8,IPO9,ITGA2,ITGAL,ITGAV,ITGB1BP1,ITPR1,ITSN2,JMJD6,KALRN,KANK1,KCNA6,KCNAB2,KCNB1,KCNIP4,KCNK6,KCNMA1,KCNN2,KDELR2,KEL,KIF13A,KIF15,KIF1A,KIF1BP,KIF23,KLHL20,KLHL24,KLHL3,KMT2A,LAMP2,LAMTOR1,LAPTM4B,LAT,LCN10,LCN12,LCN2,LCP1,LDLRAD3,LDLRAP1,LGR4,LIF,LIMK1,LITAF,LLGL2,LMBR1L,LOXL4,LRAT,LRP6,LRPPRC,LRRTM1,LTF,LTV1,LYNX1,LYPLA1,LYST,LZTS2,M6PR,MAGOHB,MAL2,MALT1,MAP1S,MAP4K2,MAP6,MAPK8,MAPK8IP3,MCFD2,MCUR1,MDM2,MEF2C,MEGF10,MFF,MFGE8,MFSD14A,MFSD2A,MGRN1,MIA3,MIDN,MINK1,MIP,MITD1,MLPH,MON2,MPPE1,MRC2,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTOR,MTTP,MTX1,MTX2,MTX3,MVP,MYH10,MYH9,MYLK,MYO10,MYO18A,MYO1B,MYO1G,NAGPA,NAPB,NAPG,NASP,NCBP2,NCBP3,NCK1,NCKIPSD,NCOA1,NCOA2,NCOR1,NDC1,NDE1,NDUFA9,NDUFAF6,NECTIN1,NEDD4L,NF1,NFE2L2,NIPAL1,NISCH,NKAIN4,NLGN3,NLRP12,NME4,NMT1,NNT,NOP58 899.04 0.01381 0.216149516666667 GO:0000380 alternative mRNA splicing, via spliceoso... biological_process 47 16 CDK13,HNRNPL,HNRNPM,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,RSRC1,SAP18,SFPQ,SREK1,THRAP3,TRA2B,WTAP 9.23 0.01433 0.223915191347754 GO:0002832 negative regulation of response to bioti... biological_process 32 12 ACOD1,C1QBP,EIF2AK2,HAVCR2,IL2RA,LTF,PCBP2,PPM1B,SEC14L1,SIRT2,TARBP2,TRIM38 6.28 0.01441 0.224791212624585 GO:0006366 transcription from RNA polymerase II pro... biological_process 1991 428 ABCA2,ABLIM3,ACTL6A,ADCYAP1,AEBP1,AGO1,AGO2,AHR,AKNA,AKT1,ANXA4,APBB1,ARHGEF2,ARID4A,ASH1L,ASUN,ATF2,ATF4,ATF7IP,ATP2B4,ATRX,ATXN7,AURKB,BATF2,BCAS3,BLZF1,BMPR1B,BPTF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BTF3,BUD31,C14orf166,C1QBP,CAMTA1,CAND1,CARF,CASK,CCNA1,CCNC,CCNL2,CCNT1,CCNT2,CD81,CDC6,CDH13,CDK12,CDK13,CDK5RAP3,CDK7,CDON,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHRD,CHTOP,CHUK,CIR1,CNOT2,CNOT7,COPS2,CPEB3,CPSF3L,CREB5,CREM,CRYM,CSRNP3,CSTF1,CSTF3,CTBP1,CTDSPL2,CTR9,CUL3,CUX1,DAB2IP,DCAF6,DDX20,DDX39B,DHFR,DICER1,DMRT2,DMTF1,DOT1L,DR1,DTX1,E2F5,E2F7,EAF2,EAPP,EBF4,EGFR,EHMT1,EHMT2,EIF2A,ELF1,ELF3,ELL2,ELP2,ELP4,ELP6,EN1,ENY2,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EZH2,FADD,FAM200B,FAM58A,FBN1,FGFR1,FIP1L1,FKBP8,FOXJ1,FOXR1,FUBP1,GABPB1,GATAD2A,GATAD2B,GDF9,GLI1,GPC3,GRHL1,GRHL2,GSK3B,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GZF1,H2AFY,HDAC1,HDAC2,HDAC7,HDAC8,HDAC9,HEXB,HEYL,HIVEP3,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPK,HOXA10,HOXA7,HOXB1,HSF2BP,HSF4,HSPH1,ICE1,ICE2,IL1B,IMPACT,INO80,INTS10,INTS12,INTS6,INTS8,IRF2,IRF5,ITGA6,ITGB1BP1,JADE1,JAZF1,JUND,KANK2,KAT2B,KLF16,KMT2A,KMT2D,LBX1,LCORL,LEO1,LIF,LITAF,LMO2,LPIN1,LRP6,LYL1,MAFK,MAGED1,MAP2K5,MBD3,MDM2,MDM4,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,MLX,MLXIP,MNAT1,MOSPD1,MSX2,MTDH,MTF2,MYB,MYF6,MYSM1,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NEDD4L,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFKBID,NFYA,NIPBL,NLRC5,NMI,NPAS3,NR2C1,NR3C1,NR3C2,NUCKS1,NUDT21,OGT,ONECUT2,PABPN1,PAWR,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBP3,PDE2A,PHF12,PHF14,PHIP,PIAS1,PIK3R2,PIN1,PIR,PKNOX2,PLK3,POLA1,POLDIP3,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POU2F2,PPP1R12A,PRDM16,PRRX1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTPRN,PURA,RBBP7,RBBP8,RBL1,RBMX,RBPJ,RECQL5,RFX2,RFX5,RFX7,RGMA,RLF,RNF14,RNF2,RNF4,RNF8,RNPS1,RORC,RPRD2,RPS6KA1,RXRA,RYR2,SAP18,SCAF1,SCAP,SEMA4D,SENP2,SFPQ,SIM1,SIM2,SIRT2,SIX1,SIX3,SKIL,SLC30A9,SLTM,SMAD2,SMAD4,SMAD9,SMARCA2,SMARCA5,SMARCD1,SMARCD2,SMARCE1,SMYD2,SMYD3,SNAI3,SNAPC3,SNAPC4,SNRPE,SNRPF,SORBS3,SOX6,SP1,SP3,SPAG8,SRSF11,SRSF5,SRSF7,SS18,STAT6,STRAP,SUB1,SUMO2,SUPT20H,SUPT4H1,TAF1A,TAF1C,TAF2,TARBP1,TBK1,TBL1XR1,TBPL1,TBX20,TBX3,TCEA2,TCEB1,TCERG1,TCF12,TCF20,TCF25,TCF7,TCFL5,TEAD1,TFEB,TFR2,TGFB1,TGFB1I1,TGIF1,THOC1,THOC2,THOC7,THRAP3,TIAL1,TLR9,TNKS,TP63,TRAK1,TRIM29,TSC22D3,TTC21B,TTF1,TWSG1,TYMS,UBA52,UBE3A,USP15,USP3,USP9X,VEGFA,WDR75,WHSC1,WNT10B,WWC2,WWOX,WWTR1,XIAP,XPO1,YBX3,ZBED4,ZBED5,ZBTB20,ZC3H12A,ZC3H8,ZEB1,ZFYVE16,ZMYM1,ZMYM2,ZMYM5,ZNF143,ZNF148,ZNF18,ZNF219,ZNF254,ZNF280D,ZNF292,ZNF431,ZNF444,ZNF451,ZNF518A,ZNF518B,ZNF613,ZNF667,ZSCAN21,ZSCAN5A 390.91 0.01445 0.225041376451078 GO:0015936 coenzyme A metabolic process biological_process 18 8 ACACA,ACAT1,COASY,CROT,PANK1,PANK3,PANK4,PPCDC 3.53 0.01454 0.22532201320132 GO:0032607 interferon-alpha production biological_process 18 8 AZI2,HAVCR2,HSPD1,IRF5,NMI,TBK1,TLR7,TLR9 3.53 0.01454 0.22532201320132 GO:0050687 negative regulation of defense response ... biological_process 18 8 C1QBP,EIF2AK2,IL2RA,PCBP2,PPM1B,SEC14L1,TARBP2,TRIM38 3.53 0.01454 0.22532201320132 GO:0051297 centrosome organization biological_process 108 31 AURKA,BRCA1,CENPJ,CEP135,CEP192,CEP63,CHD3,CHMP3,CHMP5,CHORDC1,DCTN1,FES,GEN1,HAUS3,KIAA0753,MDM1,NDE1,OFD1,PCM1,PLK4,PPP1R12A,SASS6,SDCCAG8,SGO1,SSX2IP,TMEM67,TUBGCP5,USP33,UVRAG,XPO1,XRCC3 21.2 0.01470 0.226769557377049 GO:0010565 regulation of cellular ketone metabolic ... biological_process 190 50 ACADVL,AKT1,ARPP19,ATP2B4,BRCA1,CLK2,DLAT,DLD,DUOXA1,EIF6,KAT2B,MID1IP1,MTOR,NCOR2,OAZ1,OAZ2,OGT,PDHB,PDK3,PPP4R3B,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTPN2,PXYLP1,RANBP2,RGN,SCAP,SERPINA12,SIRT5,STAR,STARD4,SUPT20H 37.3 0.01471 0.226769557377049 GO:0032435 negative regulation of proteasomal ubiqu... biological_process 51 17 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,KLHL40,LCMT1,N4BP1,PBK,PSMG2,SDCBP,TEX14,TLK2,TTK,WAC,XRCC3,ZNF207 10.01 0.01473 0.226769557377049 GO:0051785 positive regulation of nuclear division biological_process 51 17 AURKA,CUL3,EGF,H2AFY,IL1B,MSX2,NPM2,NSMCE2,NUSAP1,PDGFRB,PHIP,PLCB1,SIRT2,SLF1,TGFA,TGFB1,UBE2B 10.01 0.01473 0.226769557377049 GO:0051129 negative regulation of cellular componen... biological_process 542 127 ADIPOR1,AKT1,ANTXR1,ANXA2,ARHGAP4,ARHGAP6,ARHGEF1,ARHGEF15,ARHGEF2,ATG3,ATXN2,BCAS3,BRCA1,BUB1B,C16orf45,CAPZA1,CARMIL2,CDC42,CERS2,CFLAR,CLASP1,CLASP2,CLDN7,CLU,CRBN,CSNK2A1,CSNK2A2,CTBP1,DAB2IP,DCC,DNM3,DYNC1LI1,EML2,EPHA4,EPHB2,EVL,FHOD3,FKBP4,GAK,GEN1,GMFB,GMFG,GORASP1,GSK3B,GSN,H2AFY,HDAC2,HDAC6,HNRNPC,HNRNPU,HORMAD1,IFRD1,IMPACT,ITGB1BP1,ITM2C,KANK1,KLK8,LCMT1,LIF,LIG3,LRRTM1,LYPLA1,MALSU1,MAP6D1,MDM1,MDM2,MID1IP1,MTBP,MTF2,MYOC,NAT10,NLGN3,NME6,OMA1,OPA1,PAFAH1B1,PAQR3,PFN2,PHF1,PICK1,PKDCC,PRKCZ,PSMG2,PTEN,PTK2,RAP1GAP2,RAPGEF2,RGMA,RNF6,RTN4,RUFY3,SCAMP5,SDCBP,SDHAF2,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SIRT2,SNAPIN,SORL1,SPTB,SPTBN1,SPTBN4,STRAP,TBX20,TEX14,TFIP11,TGFB1,THY1,TIGAR,TMC8,TMEFF2,TMEM67,TOM1L1,TRIOBP,TRIP12,TTK,TWF1,UBE2B,ULK2,VIL1,WAPL,XRCC3,ZNF207,ZNF451 106.42 0.01494 0.229626088379705 GO:0009142 nucleoside triphosphate biosynthetic pro... biological_process 75 23 ADK,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CMPK1,DTYMK,GBAS,IMPDH1,MT-ATP6,NME4,NME5,NME6,NME7,NME9,SLC25A13,SUCLG1,SURF1,TBPL1,TGFB1,TYMS 14.73 0.01499 0.230018120915033 GO:1901293 nucleoside phosphate biosynthetic proces... biological_process 325 80 ACACA,ACAT1,ADA,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADK,ADNP,AK2,AK6,AKAP12,AMDHD2,AMPD3,APLP1,APRT,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CALM1,CMPK1,COASY,DCTD,DHFR,DTYMK,ENTPD8,FLAD1,GABBR1,GARS,GART,GBAS,GIPR,GMPS,GNPDA2,GRM7,GRM8,GUK1,HPRT1,HTR2B,IMPDH1,MT-ATP6,MTHFD1,MTHFD2L,NADK,NADSYN1,NAGK,NF1,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NOS3,OPRM1,PANK1,PANK3,PANK4,PDE2A,PDZD3,PGM3,PPCDC,PTK2B,RRM2B,SLC25A13,SUCLG1,SURF1,TBPL1,TGFB1,TK1,TSHR,TYMS,UGDH,UGP2,UPRT 63.81 0.01517 0.231502609400324 GO:0050771 negative regulation of axonogenesis biological_process 67 21 ARHGAP4,ARHGEF1,CERS2,DCC,EPHA4,EPHB2,IFRD1,KLK8,PTEN,PTK2,RGMA,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,THY1,ULK2 13.15 0.01520 0.231502609400324 GO:0075733 intracellular transport of virus biological_process 67 21 AAAS,DDX39B,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,THOC1,THOC2,THOC7,UBA52,XPO1 13.15 0.01520 0.231502609400324 GO:1902583 multi-organism intracellular transport biological_process 67 21 AAAS,DDX39B,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,THOC1,THOC2,THOC7,UBA52,XPO1 13.15 0.01520 0.231502609400324 GO:0043984 histone H4-K16 acetylation biological_process 25 10 BRCA1,JADE1,KANSL1,KANSL1L,KANSL2,KAT7,KMT2A,MEAF6,OGT,PHF20 4.91 0.01521 0.231502609400324 GO:0045860 positive regulation of protein kinase ac... biological_process 454 108 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,ATP2B4,BAX,BIRC7,BRAF,CACUL1,CALM1,CCDC88A,CCNC,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC6,CHRNA3,CHRNA7,CSF1R,DAB2IP,DDR2,DUSP9,ECT2,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM150A,FAM58A,FGFR1,FRS2,GADD45G,GPRC5B,HACD3,HSPH1,HTR2B,IGF1R,IL1B,IRAK1,ITGB1BP1,KRAS,LAMTOR3,LAT,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NOX4,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PDCD10,PDE5A,PDGFRB,PIK3CA,PIK3CB,PIK3R5,PPP2R3C,PRKAR2A,PRKCZ,PRLR,PTK2,PTK2B,RALB,RAP1A,RAPGEF2,RELN,SASH1,SHC2,SNX9,SPAG9,SPDYA,TAB2,TAB3,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TOM1L1,TRAF4,UBA52,VEGFA,WNT11,ZP4 89.14 0.01537 0.233559336569579 GO:0090068 positive regulation of cell cycle proces... biological_process 226 58 ATRX,AURKA,AURKB,BAX,BRCA1,BRD4,CDC42,CDC6,CENPJ,CNOT2,CNOT7,CNOT8,CSPP1,CUL3,CUL4B,DAB2IP,DYNC1LI1,E2F7,ECT2,EGF,GEN1,H2AFY,HMGA2,IL1B,INO80,KIF23,MDM2,MDM4,MSX2,MTBP,NPM2,NSMCE2,NUSAP1,PBX1,PCBP4,PDGFRB,PHIP,PKP4,PLCB1,PLK3,PLK4,PLRG1,PRMT1,RACGAP1,RAD51C,RRP8,SFPQ,SIRT2,SLF1,TGFA,TGFB1,UBA52,UBE2B,UBE2E2,WIZ,WNT10B,XRCC3,ZNF385A 44.37 0.01548 0.234257385826772 GO:0045787 positive regulation of cell cycle biological_process 298 74 AKT1,ASNS,ATRX,AURKA,AURKB,BAX,BRCA1,BRD4,CCNC,CCNL2,CCNT1,CCNT2,CDC42,CDC6,CENPJ,CNOT2,CNOT7,CNOT8,CSPP1,CUL3,CUL4B,DAB2IP,DYNC1LI1,E2F7,ECT2,EGF,EGFR,EIF4E,FAM58A,FGFR1,GEN1,H2AFY,HMGA2,IL1B,INO80,KIF23,LRP6,MDM2,MDM4,MSX2,MTBP,NPM2,NSMCE2,NUSAP1,PAFAH1B1,PBX1,PCBP4,PDGFRB,PHIP,PKP4,PLCB1,PLK3,PLK4,PLRG1,PRMT1,RACGAP1,RAD51C,RPS6KB1,RRP8,SFPQ,SIRT2,SLF1,SPDYA,SRPK2,TBX3,TGFA,TGFB1,UBA52,UBE2B,UBE2E2,WIZ,WNT10B,XRCC3,ZNF385A 58.51 0.01549 0.234257385826772 GO:1902531 regulation of intracellular signal trans... biological_process 1583 344 ABR,ADA,ADCYAP1,ADIPOR1,ADORA1,AGO1,AIP,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKR1B1,AKT1,ALOX15,ANKRD6,ARAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL2BP,ASH1L,ATP2B4,ATP2C1,ATR,AURKA,AURKB,BAG4,BANP,BAX,BCL2,BCLAF1,BIRC3,BIRC7,BOK,BRAF,BRCA1,BRD4,BRD7,BRIP1,C1QBP,C3orf33,C5AR2,CASP8,CCL25,CD44,CD74,CD81,CDC42,CDH13,CDK12,CDK5RAP3,CDON,CFLAR,CHAD,CHD3,CHN1,CHRNA7,CHUK,CPNE1,CSF1R,CSNK2A1,CSNK2A2,CUL3,CYLD,CYTH4,DAB2IP,DAG1,DNA2,DNAJA1,DNM1L,DOT1L,DUSP16,DUSP9,DYRK2,ECT2,EEF1D,EGF,EGFR,EHMT1,EHMT2,EIF2AK2,ELP2,EPHA4,EPS8L1,ESR1,EZH2,FADD,FAF1,FAM110C,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FAS,FBXW11,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FRS2,GADD45G,GDF9,GDI2,GMIP,GNA12,GPR35,GPRC5B,GSTP1,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC7,HGS,HIPK3,HTR2B,HUS1,IGF1R,IL15,IL1B,IL22RA2,INPP5B,IRAK1,IRAK4,ITGB1BP1,ITPR1,ITSN2,KALRN,KANK1,KAT6A,KRAS,L3MBTL1,LAMTOR1,LAMTOR3,LIF,LIMD1,LITAF,LMO3,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MARVELD3,MBD3,MCF2,MCF2L,MDM2,MDM4,MEAF6,MGRN1,MIER1,MINK1,MST1R,MTDH,MTOR,MYOC,NCOR1,NDRG2,NEK10,NF1,NFKBID,NLRP12,NOX1,NOX4,NPRL3,NTRK2,NTRK3,OCRL,OGT,OPRK1,OPRM1,OSBPL8,P2RX5,P2RY8,PAFAH1B1,PAK1,PAK3,PAQR3,PBK,PDCD10,PDE5A,PDGFRB,PELI1,PEX5L,PHF20,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R5,PIN1,PIP5K1A,PIP5K1C,PLA2G5,PLCB1,PLEKHG2,PLEKHG6,PLK3,PLXNB1,PODN,PPM1B,PPP2R1A,PPP2R5C,PRKCZ,PRLR,PRMT1,PRMT5,PRR5L,PSD3,PSD4,PTEN,PTK2,PTK2B,PTPN13,PTPN2,PTPN6,PTTG1IP,PUM2,RAC2,RACGAP1,RAD17,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAPGEF2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP4,RBBP4,RBBP7,RBBP8,RBCK1,RELN,RELT,RFC2,RFC4,RGN,RGS14,RGS3,RHOC,RHOF,RHOT1,RMI1,ROBO1,ROS1,RPA3,RPS6KA6,RRAGB,RTN4RL2,SASH1,SCAI,SDCBP,SEC14L1,SEH1L,SEMA4D,SEMA7A,SENP2,SEPT4,SERPINA12,SGSM3,SHC2,SIPA1,SLC38A9,SMAD4,SMYD2,SORBS3,SORL1,SOS1,SPAG9,SPATA13,SPRY1,SSX2IP,STAMBP,STAP2,STK25,TAB2,TAB3,TAF2,TANK,TBC1D10C,TBK1,TELO2,TGFA,TGFB1,TGFBR1,TLR7,TLR9,TMBIM4,TNFRSF10B,TNFRSF19,TNFRSF25,TOPBP1,TP63,TRADD,TRAF4,TRIM38,TRIM5,TRIO,TRIP10,TRIP6,UBA52,UBE2B,UBE2V1,UBE3A,VAV1,VEGFA,WNT11,WRN,WWC2,XIAP,ZAP70,ZC3H12A,ZDHHC17,ZNF385A 310.81 0.01551 0.234257385826772 GO:0006904 vesicle docking involved in exocytosis biological_process 36 13 CPLX2,EXOC4,EXOC6,EXOC6B,KCNB1,RALB,SCFD1,SCFD2,STXBP2,SYTL2,VPS11,VPS45,YKT6 7.07 0.01561 0.234257385826772 GO:0010604 positive regulation of macromolecule met... biological_process 2762 584 ABI1,ABLIM3,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AGO1,AGO2,AHR,AKNA,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD49,ANKRD6,ANXA2,APBB1,ARHGAP8,ARHGEF2,ARID1B,ARID4A,ARIH1,ARL2BP,ASH1L,ATAD1,ATF2,ATF4,ATF7IP,ATG4B,ATMIN,ATOH8,ATP2B4,ATR,ATRX,ATXN7,AURKA,AURKB,BAG4,BANP,BAX,BCAS3,BCL2,BCLAF1,BIRC3,BIRC7,BMPR1B,BOK,BOLL,BPTF,BRAF,BRCA1,BRD4,BRD7,BTK,BUB1B,BUD31,C14orf166,C1QBP,C5AR2,CACUL1,CALM1,CAMK2A,CAMTA1,CAND1,CARF,CASK,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CD44,CD46,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC6,CDCA2,CDH1,CDH13,CDK5RAP3,CDK7,CDON,CEP290,CFLAR,CHD1,CHD6,CHD7,CHFR,CHRNA3,CHRNA7,CHTOP,CHUK,CLU,CNOT7,CNOT8,CNTN1,COL4A3,CPEB3,CR1,CREB5,CREM,CSF1R,CSNK2A1,CSNK2A3,CSRNP3,CTBP1,CTC1,CTR9,CUL1,CUL3,CUL4B,CYBB,DAB2IP,DAPK1,DCAF6,DCUN1D4,DDR2,DDX39B,DIABLO,DMRT2,DNA2,DOCK7,DOT1L,DROSHA,DUSP9,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,ECT2,EGF,EGFR,EIF2A,EIF2AK2,EIF6,ELF1,ELF3,EN1,ENPP2,ENY2,EPHA4,ERC1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,EYA3,EYA4,EZH2,FADD,FAM150A,FAM58A,FANCI,FAS,FBXO22,FBXW11,FCER2,FGFR1,FNTA,FOXJ1,FOXN3,FOXN4,FRS2,FUBP1,FZR1,GABPB1,GADD45G,GCLC,GDF9,GGA1,GLI1,GPBP1,GPBP1L1,GPC3,GPRC5B,GRHL1,GRHL2,GSK3B,GSN,GTF2B,H2AFY,HACD3,HAVCR2,HDAC1,HDAC2,HDAC6,HEATR1,HEXB,HEYL,HGS,HIVEP3,HLTF,HMGA2,HMGN1,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA7,HOXB1,HSF4,HSPA8,HSPD1,HSPH1,HTR2B,ICE1,ICE2,IGF1R,IL15,IL1B,IMPACT,INO80,IRAK1,IRF2,IRF5,ITGA2,ITGA6,ITGB1BP1,ITGB8,JADE1,JUND,KAT2B,KAT6A,KDM6A,KDM7A,KLF6,KMT2A,KMT2D,KMT2E,KRAS,LAMTOR1,LAMTOR3,LAT,LEO1,LGR4,LIF,LMO2,LPIN1,LRP6,LTF,LYL1,MADD,MAFK,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MBTPS2,MDM2,MED12L,MED13,MED14,MED16,MED21,MED24,MED30,MEF2A,MEF2C,MEIS2,MINK1,MNAT1,MOB2,MOSPD1,MST1R,MTCH1,MTDH,MTF2,MTOR,MYB,MYF6,MYSM1,NAA16,NCBP2,NCK1,NCOA1,NCOA2,NCOA6,NEDD4L,NEK10,NEK7,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFYA,NIF3L1,NIPBL,NKD1,NLRC5,NLRP12,NOX1,NOX4,NPAS3,NPM2,NR3C1,NRDC,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,NUCKS1,NVL,OAZ1,OAZ2,OGT,OLFM1,ONECUT2,OPRK1,OPRM1,OSBPL8,PABPC1,PAK1,PAK2,PAK3,PAWR,PAX2,PAX3,PAX7,PAXBP1,PBX1,PCBD1,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PHIP,PIAS1,PICK1,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R5,PIN1,PLA2G10,PLA2G5,PLCB1,PLK3,PNKP,PNPT1,POLDIP3,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POT1,POU2F2,PPP1R12A,PPP1R7,PPP2R3C,PRDM16,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRR5L,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPRN,PTTG1IP,PXYLP1,RALB,RAP1A,RAP1B,RAPGEF2,RBCK1,RBL1,RBMX,RBPJ,RBPMS,RCHY1,RELN,RELT,RFC2,RFC4,RGMA,RGN,RHBDD1,RIF1,RIMS1,RLF,RNF138,RNF14,RNF166,RNF25,RNF4,RNF6,RNF8,ROBO1,RORC,RPS6KA1,RPS6KB1,RPS6KB2,RXRA,SASH1,SCAP,SCYL2,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SERP1,SF3B1,SHC2,SIRT2,SIX1,SIX3,SLC30A9,SLF1,SMAD2,SMAD4,SMAD9,SMARCA2,SMARCA5,SMARCAD1,SMARCD1,SMYD3,SNX9,SORBS3,SORL1,SOX6,SP1,SP3,SPAG8,SPAG9,SPDYA,SPRTN,SRPK2,SRSF5,SS18,STAP2,STAR,STAT6,STK25,STX5 542.29 0.01571 0.234257385826772 GO:0051493 regulation of cytoskeleton organization biological_process 422 101 ACTR2,ACTR3C,ALOX15,ANKRD53,ARF1,ARHGAP6,ARHGEF15,ARHGEF2,ARPC1A,ARPC1B,ATAT1,AURKA,BAG4,BCAS3,BORA,BRAF,BRCA1,C16orf45,CAMSAP3,CAPZA1,CARMIL2,CCDC88A,CDC42,CDC42EP3,CELSR1,CENPJ,CHMP3,CHMP5,CHORDC1,CLASP1,CLASP2,CLIP1,CLTC,CSF1R,CXCL12,CYFIP1,CYLD,DAPK3,DCTN1,ECT2,EML2,EVL,FCHSD1,FES,FHOD3,FKBP4,FMN1,GEN1,GMFB,GMFG,GSN,HDAC6,ITGB1BP1,JAM3,KANK1,LIMK1,MAP6D1,MDM1,MEF2C,MID1IP1,MTOR,MYOC,NCK1,NEB,NOX4,NTRK3,PAFAH1B1,PAK1,PAK3,PDGFRB,PFDN2,PFN2,PHLDB1,PICK1,PLK4,PLXNB1,PTK2,PTK2B,RACGAP1,RNF4,SENP6,SIRT2,SLAIN2,SORBS3,SPAG5,SPTB,SPTBN1,SPTBN4,STMN4,SYNPO,SYNPO2,TGFB1,TGFBR1,TMEFF2,TMEM67,TRIOBP,TWF1,VIL1,WNT11,XPO1,XRCC3 82.86 0.01578 0.234257385826772 GO:0090150 establishment of protein localization to... biological_process 353 86 ADORA1,AKT1,ANK2,ANK3,ANXA2,APPL1,ARFRP1,ARHGEF16,ARL6,ATG3,ATG4B,BAX,BBS1,BBS2,BCL2,BLZF1,BRAF,C2CD5,CASP8,CDH1,CLASP2,CNST,DPP10,EFR3A,EGFR,GAK,GCC2,GET4,GOLGA4,GOLGA7,ITGB1BP1,KCNB1,KIF13A,LDLRAP1,LYPLA1,MAPK8,MFF,NMT1,NUP155,NUP54,PACS2,PDZK1,PEX16,PEX3,PIP5K1A,PKDCC,PKP2,RAB3GAP2,RAB3IP,REEP1,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SDCBP,SEC63,SPTBN1,SPTBN4,SRP19,SSR1,SSR2,SSR3,TMED2,TP63,TRAM1,UBA52,VAMP4,VIL1,YWHAQ,YWHAZ 69.31 0.01583 0.234257385826772 GO:0000972 transcription-dependent tethering of RNA... biological_process 6 4 NUP107,NUP155,NUP98,RAE1 1.18 0.01584 0.234257385826772 GO:0006498 N-terminal protein lipidation biological_process 6 4 HHATL,MAP6D1,NMT1,PPM1B 1.18 0.01584 0.234257385826772 GO:0009202 deoxyribonucleoside triphosphate biosynt... biological_process 6 4 ADK,DTYMK,TBPL1,TYMS 1.18 0.01584 0.234257385826772 GO:0017196 N-terminal peptidyl-methionine acetylati... biological_process 6 4 NAA16,NAA20,NAA25,NAA60 1.18 0.01584 0.234257385826772 GO:0035733 hepatic stellate cell activation biological_process 6 4 GCLC,GCLM,PDGFRB,RPS6KA1 1.18 0.01584 0.234257385826772 GO:0042796 snRNA transcription from RNA polymerase ... biological_process 6 4 ICE1,ICE2,SNAPC4,ZC3H8 1.18 0.01584 0.234257385826772 GO:0043096 purine nucleobase salvage biological_process 6 4 ADA,APRT,CECR1,HPRT1 1.18 0.01584 0.234257385826772 GO:0051026 chiasma assembly biological_process 6 4 MSH5,RNF212,TEX11,UBE2B 1.18 0.01584 0.234257385826772 GO:0060179 male mating behavior biological_process 6 4 DMRTA1,HEXB,NCOA1,PTEN 1.18 0.01584 0.234257385826772 GO:0061196 fungiform papilla development biological_process 6 4 HDAC1,HDAC2,SIX1,WNT10B 1.18 0.01584 0.234257385826772 GO:0072659 protein localization to plasma membrane biological_process 182 48 AKT1,ANK2,ANK3,ANXA2,APPL1,ARFRP1,ARHGEF16,ATP1B1,BAG4,BBS1,BBS2,BLZF1,C2CD5,CACNB3,CDH1,CLASP2,CNST,DENND4C,DPP10,EFR3A,EHD2,EPB41L3,FCHO2,FYB,GAK,GCC2,GOLGA4,GOLGA7,KCNB1,KCNIP4,KIF13A,LDLRAP1,LRP6,LYPLA1,PACS2,PIP5K1A,PKDCC,PKP2,PPIL2,PRKCZ,RAPGEF2,SCN3B,SPTBN1,SPTBN4,SYTL2,TMED2,VAMP4,VIL1 35.73 0.01592 0.235070314465409 GO:0031175 neuron projection development biological_process 770 175 ABI1,ADCYAP1,ADNP,AKT1,ANK3,APBB1,APBB2,ARF1,ARHGAP4,ARHGEF1,ATXN10,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAMSAP3,CAPRIN1,CCDC88A,CDH1,CELSR2,CERS2,CHL1,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CRTAC1,CSF1R,CTNNA1,CUL4B,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DCC,DDX56,DHFR,DICER1,DNM3,DOCK7,EGFR,EPB41L3,EPHA4,EPHB2,ETV1,EVL,EZH2,FAM150A,FARP1,FBXO7,FES,FEZ1,FEZ2,FGFR1,FKBP4,FMN1,FRY,FRYL,GAK,GOLGA4,GORASP1,GPC1,GPM6A,GPRC5B,GSK3B,HDAC2,HDAC6,HPRT1,IFRD1,ITM2C,JAM3,KALRN,KANK1,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP1S,MAP2,MAP6,MAPK8IP3,MCF2,MDM2,MEF2A,MEF2C,METRN,MINK1,MOB2,MTOR,MYH10,MYOC,NCK1,NCKIPSD,NECTIN1,NFE2L2,NLGN3,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OLFM1,OPA1,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PAX2,PLA2G10,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRMT1,PRRX1,PTEN,PTK2,PTK2B,PTPRA,PTPRK,RAP1A,RAP1GAP2,RAPGEF2,RAPH1,RELN,RGMA,RNF6,ROBO1,ROBO3,RTN4,RTN4RL2,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SGK1,SHTN1,SKIL,SLC11A2,SLC12A5,SMAD4,SNAPIN,SOS1,SPTB,SPTBN1,SPTBN4,STK25,STMN4,STRN,SZT2,THY1,TLR9,TOP2B,UBA6,ULK2,USP33,USP9X,VEGFA,WEE1,ZNF280D 151.18 0.01627 0.239861177394035 GO:0006622 protein targeting to lysosome biological_process 15 7 GCC2,GNPTG,HGS,NAGPA,SNX16,SORL1,ZFYVE16 2.95 0.01631 0.239992222222222 GO:0010975 regulation of neuron projection developm... biological_process 381 92 ADCYAP1,ADNP,AKT1,APBB1,ARF1,ARHGAP4,ARHGEF1,BRAF,CACNA1A,CAPRIN1,CCDC88A,CERS2,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CUX1,CXCL12,DAB2IP,DCC,DDX56,DNM3,EPHA4,EPHB2,EZH2,FAM150A,FBXO7,FES,FEZ1,FGFR1,FKBP4,GAK,GOLGA4,GORASP1,GPRC5B,GSK3B,HDAC2,IFRD1,ITM2C,KALRN,KANK1,KEL,KLK8,LIMK1,MDM2,MEF2C,METRN,MOB2,MTOR,NCK1,NCKIPSD,NFE2L2,NLGN3,NTRK2,NTRK3,OLFM1,OPA1,PAFAH1B1,PAK3,PAQR3,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRRX1,PTEN,PTK2,PTK2B,RAP1A,RAP1GAP2,RAPGEF2,RELN,RGMA,RNF6,ROBO1,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SKIL,SNAPIN,STK25,THY1,ULK2,VEGFA 74.81 0.01633 0.239992222222222 GO:0042992 negative regulation of transcription fac... biological_process 40 14 CYLD,DYRK2,FAF1,FBXW11,GSK3B,LITAF,MTOR,NF1,NLRP12,PPM1B,SRI,TBC1D10C,TRIP6,ZC3H12A 7.85 0.01652 0.242027020280811 GO:0072384 organelle transport along microtubule biological_process 40 14 BICD1,CDC42,CLN3,HAP1,KIF13A,KIF23,LRPPRC,MAP1S,NDE1,PAFAH1B1,PRKCZ,RAB1A,RHOT1,WDR43 7.85 0.01652 0.242027020280811 GO:0015749 monosaccharide transport biological_process 152 41 AAAS,ADIPOR2,AKT1,APPL1,ARPP19,ASPSCR1,BRAF,C2CD5,FABP5,GPC3,GRB10,IL1B,M6PR,NDC1,NFE2L2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PIK3R2,PIK3R3,PRKCZ,RAE1,RANBP2,RAP1A,RPS6KB1,SEH1L,SIRT6,SLC25A27,SLC2A5,SLC2A9,SLC5A1,STXBP4,VIL1 29.84 0.01695 0.247214839203675 GO:0071902 positive regulation of protein serine/th... biological_process 322 79 ACSL1,ADORA1,AKT1,ATP2B4,BIRC7,BRAF,CALM1,CCNC,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC6,CHRNA7,CSF1R,DAB2IP,DUSP9,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM58A,FGFR1,FRS2,GADD45G,HACD3,HTR2B,IGF1R,IL1B,IRAK1,KRAS,LAMTOR3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NOX4,NTRK3,PAK1,PAK3,PDCD10,PDE5A,PDGFRB,PIK3CB,PIK3R5,PTK2B,RALB,RAP1A,RAPGEF2,SASH1,SHC2,SPAG9,SPDYA,TAB2,TAB3,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TRAF4,UBA52,VEGFA 63.22 0.01702 0.247214839203675 GO:0002757 immune response-activating signal transd... biological_process 465 110 ABI1,ACOD1,ACTG1,ACTR2,ADA,ARPC1A,ARPC1B,BCAR1,BCL2,BIRC3,BLK,BPIFB1,BTK,C1QBP,C5AR2,CACNB3,CASP8,CD14,CD247,CD3G,CD79B,CDC42,CHUK,CLEC4E,CR1,CUL1,CYFIP1,CYLD,DAB2IP,DENND1B,DMBT1,ELF1,ESR1,FADD,FBXW11,FYB,GCSAM,HAVCR2,HLA-DPB1,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LAT,LGR4,LIMK1,LTF,MALT1,MEF2C,MYO10,MYO1G,NCK1,NCKIPSD,NRAS,OTULIN,PAK1,PAK2,PAK3,PAWR,PDE4D,PELI1,PGLYRP2,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTPN2,PTPN6,PUM2,RBCK1,SEC14L1,TAB2,TAB3,TANK,TBK1,THY1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,VAV1,XIAP,ZAP70 91.3 0.01707 0.247214839203675 GO:0010762 regulation of fibroblast migration biological_process 29 11 AKT1,ARHGAP4,BAG4,BRAF,DDR2,GNA12,ITGB1BP1,PAK3,PRR5L,TGFB1,UTS2 5.69 0.01717 0.247214839203675 GO:0033046 negative regulation of sister chromatid ... biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:0033048 negative regulation of mitotic sister ch... biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:0045841 negative regulation of mitotic metaphase... biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:0071174 mitotic spindle checkpoint biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:1902100 negative regulation of metaphase/anaphas... biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:2000816 negative regulation of mitotic sister ch... biological_process 29 11 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,LCMT1,PSMG2,TEX14,TTK,XRCC3,ZNF207 5.69 0.01717 0.247214839203675 GO:0032210 regulation of telomere maintenance via t... biological_process 44 15 ATR,AURKB,CCT3,CCT7,HNRNPC,HNRNPU,MAP2K7,MAPKAPK5,NAT10,NEK7,PNKP,POT1,SMG6,TCP1,TNKS 8.64 0.01719 0.247214839203675 GO:1904356 regulation of telomere maintenance via t... biological_process 44 15 ATR,AURKB,CCT3,CCT7,HNRNPC,HNRNPU,MAP2K7,MAPKAPK5,NAT10,NEK7,PNKP,POT1,SMG6,TCP1,TNKS 8.64 0.01719 0.247214839203675 GO:0022900 electron transport chain biological_process 105 30 COX5A,COX6A1,COX7A2L,CYB561,DLD,ETFA,IMMP2L,LYRM5,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHAF2,SDHC,SLC25A13,TAZ,UQCRB,UQCRC2,UQCRH 20.62 0.01728 0.248129174311927 GO:0032508 DNA duplex unwinding biological_process 80 24 ATRX,BRIP1,CHD1,CHD2,CHD3,CUL4B,DDB1,DDX1,DNA2,GTF2H2,GTF2H3,GTF2H5,HELB,INO80,MCM2,POT1,PURA,RAD54B,RECQL5,TOP2B,UBA52,WRN,XRCC5,ZRANB3 15.71 0.01731 0.248180473282443 GO:1990778 protein localization to cell periphery biological_process 183 48 AKT1,ANK2,ANK3,ANXA2,APPL1,ARFRP1,ARHGEF16,ATP1B1,BAG4,BBS1,BBS2,BLZF1,C2CD5,CACNB3,CDH1,CLASP2,CNST,DENND4C,DPP10,EFR3A,EHD2,EPB41L3,FCHO2,FYB,GAK,GCC2,GOLGA4,GOLGA7,KCNB1,KCNIP4,KIF13A,LDLRAP1,LRP6,LYPLA1,PACS2,PIP5K1A,PKDCC,PKP2,PPIL2,PRKCZ,RAPGEF2,SCN3B,SPTBN1,SPTBN4,SYTL2,TMED2,VAMP4,VIL1 35.93 0.01757 0.250426666666667 GO:0015758 glucose transport biological_process 148 40 AAAS,ADIPOR2,AKT1,APPL1,ARPP19,ASPSCR1,BRAF,C2CD5,FABP5,GPC3,GRB10,IL1B,NDC1,NFE2L2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PIK3R2,PIK3R3,PRKCZ,RAE1,RANBP2,RAP1A,RPS6KB1,SEH1L,SIRT6,SLC25A27,SLC2A5,SLC2A9,SLC5A1,STXBP4,VIL1 29.06 0.01760 0.250426666666667 GO:0035195 gene silencing by miRNA biological_process 48 16 AGO1,AGO2,CNOT7,CNOT8,DICER1,DROSHA,EIF6,FXR1,HNRNPA2B1,LIMD1,PUM2,RBM4,SMAD2,TARBP2,TGFB1,ZCCHC11 9.42 0.01767 0.250426666666667 GO:0006183 GTP biosynthetic process biological_process 12 6 IMPDH1,NME4,NME5,NME6,NME7,NME9 2.36 0.01772 0.250426666666667 GO:0007252 I-kappaB phosphorylation biological_process 12 6 CHUK,DAB2IP,ERC1,PRDX4,TLR7,TLR9 2.36 0.01772 0.250426666666667 GO:0009113 purine nucleobase biosynthetic process biological_process 12 6 ADA,APRT,CECR1,GART,GMPS,HPRT1 2.36 0.01772 0.250426666666667 GO:0009263 deoxyribonucleotide biosynthetic process biological_process 12 6 ADK,DTYMK,GUK1,RRM2B,TBPL1,TYMS 2.36 0.01772 0.250426666666667 GO:0060544 regulation of necroptotic process biological_process 12 6 ARHGEF2,BIRC3,CFLAR,FADD,RBCK1,YBX3 2.36 0.01772 0.250426666666667 GO:0097286 iron ion import biological_process 12 6 SLC11A2,STEAP1B,STEAP4,TF,TFR2,TFRC 2.36 0.01772 0.250426666666667 GO:0051248 negative regulation of protein metabolic... biological_process 1035 230 ACOT8,AGO1,AGO2,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANXA2,APBB1,ARPP19,ASH1L,ATF4,AZIN2,BAG4,BANP,BAX,BIRC3,BIRC6,BIRC7,BRCA1,BUB1B,C3orf33,C4A,C4B,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CD2BP2,CD44,CDC23,CDC27,CDK5RAP3,CEP192,CHAD,CHORDC1,CLN3,CLN8,CNOT2,CNST,COL4A3,CPEB1,CPEB3,CR1,CRYAB,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,DAB2IP,DAG1,DAPK1,DAPK3,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DUSP16,DUSP9,DYNC1LI1,EGFR,EIF2AK2,EIF4E,EIF6,EPRS,FARP1,FBXO7,FGFR1OP,FMN2,FOXJ1,FXR1,FZR1,GCLC,GEN1,GFRA2,GIGYF2,GMFB,GMFG,GPC3,GRB7,GSTP1,H2AFY,HAP1,HDAC1,HDAC2,HDAC6,HDAC8,HHATL,HIPK3,HNRNPD,IGF1R,IGF2BP3,IL1B,IL1R2,IMPACT,ITGAV,ITGB1BP1,ITM2C,KAT2B,KLHL40,LCMT1,LIF,LIMK1,LMO3,LRP6,LRRTM1,LRRTM3,MALSU1,MAP2K5,MARVELD3,MASTL,MDM2,MDM4,METTL14,MPHOSPH10,MTF2,MTOR,MVP,N4BP1,NCK1,NCOR1,NDRG2,NF1,NLRP12,NMI,NTRK3,OGT,OVOS2,PAFAH1B1,PAIP2,PAK2,PAQR3,PARP10,PAX2,PBK,PDCL3,PDE4D,PHF1,PIN1,PODN,PON1,POR,PPP1R1B,PPP2R1A,PRKAR2A,PRKCZ,PRMT3,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTEN,PTPN2,PTPN6,PURA,RBM4,RGN,RGS14,RGS3,RNF4,RPS6KA1,RPS6KA6,RTN4RL2,SDCBP,SEMA4D,SENP2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SF3B3,SIRT2,SMAD4,SMYD3,SORL1,SPINT2,SPOCK3,SPRY1,STRAP,SYTL2,TARBP2,TBC1D10C,TEX14,TFPI,TGFB1,THY1,TIA1,TLK2,TRIP12,TTK,UBA52,UBE2B,UBE2E1,UCHL5,UFL1,UNK,USP4,VEGFA,VIL1,WAC,WFDC2,WWTR1,XIAP,XRCC3,ZC3H12A,ZNF207,ZNF451 203.21 0.01780 0.250426666666667 GO:0060285 cilium-dependent cell motility biological_process 22 9 BBS2,CFAP20,CFAP46,DNAH17,DNAH2,DNAH3,DRC1,RSPH9,SPAG16 4.32 0.01787 0.250426666666667 GO:0002183 cytoplasmic translational initiation biological_process 9 5 CDC123,EIF3D,EIF3M,MCTS1,RBM4 1.77 0.01808 0.250426666666667 GO:0002923 regulation of humoral immune response me... biological_process 9 5 CR1,FCER2,FOXJ1,LTA,PTPN6 1.77 0.01808 0.250426666666667 GO:0006930 substrate-dependent cell migration, cell... biological_process 9 5 MYH10,NCK1,P2RY12,SDCBP,SHTN1 1.77 0.01808 0.250426666666667 GO:0007097 nuclear migration biological_process 9 5 CDC42,DCTN4,MYH10,PAFAH1B1,WDR43 1.77 0.01808 0.250426666666667 GO:0009265 2-deoxyribonucleotide biosynthetic proc... biological_process 9 5 ADK,DTYMK,GUK1,TBPL1,TYMS 1.77 0.01808 0.250426666666667 GO:0034063 stress granule assembly biological_process 9 5 ATXN2,BICD1,GRB7,OGFOD1,PUM2 1.77 0.01808 0.250426666666667 GO:0034086 maintenance of sister chromatid cohesion biological_process 9 5 H2AFY,MAU2,NIPBL,NSMCE2,SLF1 1.77 0.01808 0.250426666666667 GO:0034088 maintenance of mitotic sister chromatid ... biological_process 9 5 H2AFY,MAU2,NIPBL,NSMCE2,SLF1 1.77 0.01808 0.250426666666667 GO:0046385 deoxyribose phosphate biosynthetic proce... biological_process 9 5 ADK,DTYMK,GUK1,TBPL1,TYMS 1.77 0.01808 0.250426666666667 GO:0051639 actin filament network formation biological_process 9 5 ACTN1,CARMIL2,COBL,FHOD3,LCP1 1.77 0.01808 0.250426666666667 GO:0070933 histone H4 deacetylation biological_process 9 5 HDAC1,HDAC2,HDAC9,SIRT2,SMARCAD1 1.77 0.01808 0.250426666666667 GO:1901409 positive regulation of phosphorylation o... biological_process 9 5 CCNC,CCNL2,CCNT1,CCNT2,FAM58A 1.77 0.01808 0.250426666666667 GO:0071103 DNA conformation change biological_process 255 64 ACIN1,ANP32A,ASH1L,ATRX,BAHCC1,BRD2,BRIP1,CABIN1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CHD1,CHD2,CHD3,CUL4B,DDB1,DDX1,DNA2,ERN2,GTF2H2,GTF2H3,GTF2H5,H2AFY,HAT1,HELB,HELLS,HIST1H2BN,HMGA2,INO80,ITGB3BP,KAT6A,MCM2,MIS18BP1,NAA10,NAA60,NAP1L1,NAP1L4,NASP,NCAPG,NUSAP1,PARP10,POT1,PSME4,PURA,RAD54B,RBBP4,RBBP7,RECQL5,SART3,SMARCA5,SMC2,SMC4,SMYD3,SYCP3,TNRC18,TOP2B,UBA52,WAPL,WRN,XRCC5,ZRANB3 50.07 0.01850 0.255866715758468 GO:0048856 anatomical structure development biological_process 4974 1026 ABAT,ABI1,ABLIM3,ABR,ACADVL,ACAT1,ACE,ACIN1,ACOD1,ACSBG1,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ADA,ADAM10,ADAM22,ADAM23,ADAMTS6,ADCYAP1,ADIPOR1,ADIPOR2,ADNP,ADORA1,AEBP1,AFF3,AGFG1,AGTPBP1,AHR,AKIP1,AKR1B1,AKT1,ALDH1A3,ALDH3A2,ALOX15,ALPL,AMBRA1,AMER1,AMER3,ANGPT2,ANGPTL3,ANK2,ANK3,ANKH,ANKLE2,ANKRD11,ANKRD6,ANLN,ANO6,ANTXR1,ANXA2,ANXA4,ANXA7,APBB1,APBB2,APH1A,APLP1,APRT,ARF1,ARFRP1,ARHGAP26,ARHGAP4,ARHGAP5,ARHGEF1,ARHGEF15,ARHGEF2,ARID1B,ARID4A,ARL6,ARMC4,ASIC2,ASNS,ATAT1,ATF2,ATIC,ATMIN,ATOH8,ATP11C,ATP2B1,ATP2B4,ATP2C1,ATP5B,ATP6V0D1,ATP7B,ATRAID,ATRX,ATXN10,ATXN3,AURKA,AZI2,BATF2,BAX,BBS1,BBS2,BBX,BCAS3,BCCIP,BCHE,BCL2,BICD1,BIRC6,BLNK,BMP2K,BMPR1B,BNIP2,BOC,BOK,BPNT1,BPTF,BRAF,BRCA1,BRINP1,BRINP2,BRWD3,BSN,BTBD7,BTF3,BTK,C11orf88,C16orf45,C16orf89,C1QBP,C1QTNF5,CABYR,CACNA1A,CACNA1C,CACNA1H,CACNB3,CACNB4,CALB1,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAPRIN1,CARMIL2,CASP8,CATSPER4,CCDC114,CCDC14,CCDC66,CCDC88A,CCNB2,CCNT2,CD44,CD46,CD74,CD79B,CD9,CDC42,CDC42EP3,CDH1,CDH13,CDH23,CDK13,CDK5RAP3,CDON,CEACAM5,CELSR1,CELSR2,CENPU,CEP164,CEP290,CEP57,CEP89,CERS2,CES1,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CFLAR,CHAD,CHD2,CHD7,CHL1,CHN1,CHODL,CHRD,CHRM2,CHRNA3,CHRNA7,CHUK,CLASP1,CLASP2,CLDN11,CLDN4,CLEC3A,CLEC4E,CLEC5A,CLIP1,CLN8,CLTC,CLU,CMTM7,CNOT2,CNTN1,COBL,COL17A1,COL4A3,COL4A5,COL6A1,COL9A3,COPS2,COPS3,COX17,CPEB3,CPLX2,CPNE1,CPQ,CPS1,CRTAC1,CRYAB,CSDE1,CSF1R,CSF3R,CSNK1G1,CTC1,CTDNEP1,CTNNA1,CTNNBL1,CTNND1,CTR9,CTTNBP2,CUL1,CUL3,CUL4B,CUX1,CXADR,CXCL12,CXCL17,CXCR2,CXXC4,CYBB,CYFIP1,CYP19A1,DAAM1,DAB2IP,DAD1,DAG1,DAPK3,DCC,DCTN1,DDR1,DDR2,DDX20,DDX39B,DDX56,DDX6,DGKG,DHCR7,DHFR,DHRS2,DICER1,DKKL1,DLD,DLG2,DLG3,DMBT1,DMC1,DMPK,DMRT2,DMRTA1,DNAH11,DNAI1,DNAI2,DNM1L,DNM3,DOCK7,DOK4,DPCD,DPF1,DPPA4,DRC1,DROSHA,DSG2,DTX1,DTYMK,DUOXA1,E2F5,E2F7,EAF2,ECT2,EGF,EGFL7,EGFR,EHD2,EHMT1,EIF2AK2,EIF4E,EIF6,ELF3,ELN,EMX1,EN1,ENPP2,EPB41L3,EPHA4,EPHB2,ERO1A,ESR1,ESRRB,ETV1,ETV5,ETV6,ETV7,EVL,EXOC4,EXPH5,EYA3,EYA4,EZH2,FABP5,FADD,FAM150A,FAM161A,FAM65B,FANCA,FANCD2,FARP1,FARP2,FAS,FAT1,FBF1,FBLIM1,FBN1,FBXO22,FBXO7,FER1L5,FES,FEZ1,FEZ2,FGD3,FGD4,FGD6,FGF12,FGF5,FGFR1,FHL1,FHOD3,FKBP4,FKBP8,FMN1,FMN2,FMNL2,FNBP1L,FNDC3A,FNTA,FOXJ1,FOXN3,FOXN4,FRAS1,FRMD6,FRS2,FRY,FRYL,FUOM,FUT8,FUT9,FXR1,FZD6,FZR1,GABRA5,GAK,GALNT11,GART,GBA2,GCNT3,GDA,GDF9,GFRA2,GIGYF2,GIPR,GJB1,GLCCI1,GLI1,GMFB,GNA12,GNGT1,GNPAT,GOLGA4,GORASP1,GPC1,GPC3,GPM6A,GPRC5B,GPSM1,GRHL1,GRHL2,GSK3B,GSN,GSTP1,GTF2I,GTF3C5,GYS1,GZF1,H2AFY,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC9,HEATR9,HESX1,HEXB,HEYL,HIVEP3,HMGA2,HMGCS1,HMGN1,HNRNPD,HNRNPH3,HNRNPU,HOOK1,HORMAD1,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HPRT1,HSD17B3,HSD17B4,HSF4,HSPB11,HSPD1,HTR2B,HUS1,HYAL1,HYAL3,HYDIN,IDO1,IFRD1,IGF2BP3,IGF2R,IL15,IL1B,IL1RAPL2,IL2RA,IL4R,IMMP2L,IMPACT,INPP5B,IQCB1,IQCG,IRX4,ITGA2,ITGA6,ITGA7,ITGAV,ITGB1BP1,ITGB4,ITGB8,ITM2C,JAM3,JMJD6,JUND,KALRN,KANK1,KAT6A,KCNAB2,KDM6A,KDM7A,KEL,KIAA1217,KIF1BP,KLF6,KLHL3,KLHL40,KLK8,KMT2A,KMT2D,KMT2E,KRAS,KRIT1,KRT13,KRT16,KRT5,L3MBTL1,L3MBTL3,LAMA1,LAMC2,LARP4,LBX1,LCE1B,LCE1C,LCP1,LEO1,LFNG,LGI1,LGR4,LGR5,LHX6 976.59 0.01855 0.256180955882353 GO:0007163 establishment or maintenance of cell pol... biological_process 166 44 ACTR2,ARHGEF2,BCAS3,CARMIL2,CD3G,CDC42,CENPA,CLASP1,CLASP2,CTNNA1,DLG2,DLG3,DOCK7,FAT1,FBF1,FERMT1,FOXJ1,FRMD4A,JAM3,KANK1,KRIT1,LLGL2,MARK1,MARK3,MYH9,MYO18A,NDE1,PAFAH1B1,PRKCZ,PTK2,PTK2B,RAB11FIP2,RAP1B,RUFY3,SDCCAG8,SHTN1,SPAG5,SPDL1,SPINT2,SPRY1,STK25,WDR43,WEE1,WNT11 32.59 0.01864 0.256806671554252 GO:0090305 nucleic acid phosphodiester bond hydroly... biological_process 305 75 ABCE1,AGO1,AGO2,AKT1,APEX2,BAX,BMS1,BRCA1,CNOT2,CNOT7,CNOT8,CSTF1,CSTF3,CUL4B,DAB2IP,DDB1,DDX1,DICER1,DMC1,DNA2,DNASE1,DROSHA,EDC3,ELAC2,ENPP2,ERI2,ERN2,EXD1,EXD3,EXOSC8,GEN1,GTF2H2,GTF2H3,GTF2H5,HORMAD1,MAP1S,PAN3,PARN,PGAP1,PMS2,PNKP,PNPT1,PNRC2,POLA1,POLD3,POLD4,POLK,PPP1R8,RAD51C,RAD52,RBBP8,RCL1,REXO2,RFC2,RFC4,RNASET2,RNF138,RNH1,RPA3,RRP36,SMARCAD1,SMG6,TATDN1,TDP1,TEFM,TMBIM6,TSEN15,TSEN2,UBA52,WDR33,WRN,XRCC3,XRN1,ZC3H12A,ZRANB3 59.88 0.01865 0.256806671554252 GO:0070646 protein modification by small protein re... biological_process 140 38 ATXN3,ATXN7,BAP1,COPS2,COPS3,CYLD,DMWD,EIF3F,ENY2,FAM175B,FAM76B,MYSM1,OTUD4,SENP2,SENP6,SHMT2,STAMBP,UCHL5,USP12,USP15,USP17L17,USP17L3,USP24,USP25,USP3,USP32,USP33,USP34,USP36,USP39,USP4,USP7,USP8,USP9X,USPL1,VCPIP1,WDR20,ZC3H12A 27.49 0.01896 0.260693060029283 GO:0009636 response to toxic substance biological_process 175 46 AHR,AKR1B1,ALPL,ASNS,BAX,BCL2,CASP8,CDH1,CES1,CHUK,CPOX,CPS1,CYP2F1,DHFR,DHRS2,DHX15,EHMT1,EIF2AK2,EZH2,FAS,FBLN5,GJC2,HDAC6,HYAL1,HYAL3,MDM2,MEF2C,NFE2L2,NOS3,PDGFRB,PDZD3,PON1,PON2,RGN,RPS6KB1,RSRC1,SCFD1,SLC1A3,SLC7A11,SOD3,STAR,SZT2,TRPM6,TYMS,WAPL,ZC3H8 34.36 0.01903 0.261272997076023 GO:0032606 type I interferon production biological_process 110 31 ACOD1,AZI2,CD14,CRCP,CYLD,HAVCR2,HERC5,HSPD1,IRAK1,IRF5,NLRC5,NMI,PCBP2,PIN1,POLR1D,POLR2E,POLR2H,POLR2K,POLR3C,POLR3F,PPM1B,RNF216,STAT6,TAX1BP1,TBK1,TLR7,TLR9,TRIM38,UBA52,XRCC5,ZBTB20 21.6 0.01908 0.26157705109489 GO:0009791 post-embryonic development biological_process 89 26 AGO2,ATRX,BAX,BCL2,CCDC66,DHCR7,EMX1,FBN1,GIGYF2,HMGN1,IGF2R,ITPR1,KMT2A,MAPK8IP3,MTOR,SCUBE1,SEPP1,SERP1,SGPL1,SMAD2,SOX6,SZT2,TAPT1,TGFBR1,TIPARP,VEGFA 17.47 0.01924 0.263386064139942 GO:0001889 liver development biological_process 123 34 ACAT1,ADA,ASNS,AURKA,COBL,CPS1,CUL3,DDX39B,E2F7,EGFR,EZH2,GLI1,HMGCS1,HNRNPD,IGF2R,ITGA2,KRAS,LIMS2,MAN2A1,NF1,ONECUT2,PIK3CA,PRMT5,QDPR,RAP1A,RGN,RPL32,RPS6KA1,SEC63,SP3,SRSF5,TGFB1,TYMS,UGT1A1 24.15 0.01952 0.266830160116448 GO:2001238 positive regulation of extrinsic apoptot... biological_process 37 13 BAX,CTNNA1,CYLD,DAPK3,FADD,FAS,ITM2C,NF1,PAK2,PPP2R1A,RBCK1,TNFSF12,WWOX 7.26 0.01984 0.27081023255814 GO:0031324 negative regulation of cellular metaboli... biological_process 2238 476 ABCE1,ACADVL,ACOD1,ACOT8,AEBP1,AGO1,AGO2,AHR,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKLE2,ANXA2,ANXA4,APLP1,APOBEC3F,ARID4A,ARPP19,ASH1L,ATF2,ATF4,ATF7IP,ATOH8,ATP2B4,ATR,ATRX,ATXN2,ATXN7,AURKB,BAG4,BAHCC1,BAX,BAZ2A,BCL2,BCLAF1,BIRC3,BIRC6,BIRC7,BPTF,BRCA1,BRD7,BUB1B,C1D,C1QBP,C3orf33,C4A,C4B,CACNA1A,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CBX5,CCNT1,CD2BP2,CD44,CDC23,CDC27,CDC6,CDK5RAP3,CEP192,CHAD,CHCHD3,CHORDC1,CIART,CIR1,CLK2,CLN3,CLN8,CNOT2,CNST,COL4A3,COPS2,CPEB1,CPEB3,CR1,CREM,CRYAB,CRYM,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTC1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAG1,DAPK1,DAPK3,DAPL1,DDX20,DEPDC1,DICER1,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DOT1L,DR1,DUSP16,DUSP9,DYNC1LI1,E2F7,EAPP,EHMT1,EHMT2,EIF2AK2,EIF4A2,EIF4E,EIF6,ELF3,ELP2,EN1,EPRS,ERN2,ESR1,ETV6,ETV7,EZH2,FARP1,FBXO7,FBXW11,FGFR1,FGFR1OP,FOXJ1,FOXN3,FXR1,FZD6,FZR1,GABBR1,GATAD2A,GATAD2B,GCLC,GEN1,GFRA2,GIGYF2,GLA,GMFB,GMFG,GPC3,GRB10,GRB7,GRM7,GRM8,GSK3B,GSTP1,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELB,HELLS,HESX1,HEYL,HHATL,HIPK3,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HOXA7,HSF4,HSPA8,HTR2B,HUS1,IGF1R,IGF2BP3,IL1B,IL1R2,IMPACT,IRAK1,IRF2,ITGAV,ITGB1BP1,ITM2C,JAZF1,JUND,KANK2,KAT2B,KAT6A,KLF16,KLHL40,KMT2D,L3MBTL1,LANCL2,LCMT1,LGR4,LHX9,LIF,LIG3,LIMD1,LIMK1,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,MAGED1,MALSU1,MAP2K5,MARVELD3,MASTL,MBD3,MDM2,MDM4,MEF2A,MEF2C,MEIS2,METTL14,MIDN,MIER1,MLX,MORF4L1,MOSPD1,MPHOSPH10,MSX2,MTA3,MTDH,MTF2,MTOR,MVP,MXD3,MYB,MYF6,N4BP1,NAB1,NAT10,NCK1,NCOA2,NCOR1,NCOR2,NDRG2,NEDD4L,NF1,NFE2L3,NFKBID,NIPBL,NKRF,NLRC5,NLRP12,NMI,NR2C1,NTRK3,OGT,OPRM1,ORMDL2,ORMDL3,OTULIN,OVOS2,PABPC1,PAFAH1B1,PAIP2,PAK2,PAQR3,PARP10,PARPBP,PAWR,PAX2,PAX4,PAXBP1,PBK,PCBP3,PDCL3,PDE2A,PDE4D,PDZD3,PELI1,PHF1,PHF12,PHF14,PIAS1,PIN1,PLA2G10,PLCB1,PLK3,PODN,PON1,POR,POT1,PPP1R1B,PPP2R1A,PRDM16,PRICKLE1,PRKAR2A,PRKCZ,PRMT3,PRR5L,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTBP2,PTEN,PTPN2,PTPN6,PTPRK,PURA,RAD17,RANBP2,RAPGEF2,RBBP7,RBBP8,RBCK1,RBL1,RBM4,RBMX,RBPJ,RECQL5,RFX5,RGN,RGS14,RGS3,RNF2,RNF4,RNF8,RNPS1,RPS6KA1,RPS6KA6,RRP8,RTN4RL2,RUNX1T1,RXRA,SAP18,SDCBP,SEMA4D,SENP2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SFPQ,SIM2,SIRT2,SIRT5,SIRT6,SIX1,SIX3,SKIL,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCE1,SMC1A,SMYD2,SMYD3,SNAI3,SORBS3,SORL1,SOX6,SP3,SPINT2,SPOCK3,SPRY1,SRSF7,STAT6,STRAP,SUMO1,SUPT4H1,SYTL2,TAB2,TAB3,TARBP2,TAX1BP1,TBC1D10C,TBL1XR1,TBPL2,TBX20,TBX3,TCERG1,TCF25,TCF7,TEX14,TFIP11,TFPI,TGFB1,TGIF1,THOC1,THY1,TIA1,TIGAR,TLK2,TLR9,TMBIM6,TNRC18,TP63,TRA2B,TRIM29,TRIP12,TSC22D3,TTF1,TTK,UBA3,UBA52,UBE2B,UBE2E1,UCHL5,UFL1,UNK,USP3,USP4,USP7,USP9X,VEGFA,VIL1,WAC,WAPL,WFDC2,WHSC1,WNT10B,WNT11,WWC2,WWP1,WWTR1,XIAP,XPO1,XRCC3,XRCC5,YBX3,YWHAQ,ZBTB20,ZC3H12A,ZC3H8,ZEB1,ZNF148,ZNF207,ZNF219,ZNF224,ZNF253,ZNF254,ZNF280D,ZNF418,ZNF431,ZNF451,ZNF613,ZNF706,ZNF91,ZRANB3 439.41 0.02003 0.273006865021771 GO:0006520 cellular amino acid metabolic process biological_process 496 116 ABAT,ACAD8,ACAT1,ALDH18A1,ALDH1L1,ALDH7A1,AMD1,AMT,ASNS,ASPG,ATF4,ATIC,ATP2B4,AZIN2,BCKDHB,BCKDK,CACNA1A,CARS,CHAC2,CKMT2,CLN3,CNDP2,CPQ,CPS1,CRYM,DALRD3,DARS,DARS2,DBT,DHFR,DLD,DPYS,DUOXA1,ENOPH1,ENOSF1,EPRS,ERO1A,FTCD,GARS,GART,GCAT,GCLC,GCLM,GCSH,GGCT,GGH,GGT1,GLRX2,GLS,GLS2,GMPS,GSTA5,GSTM5,GSTP1,HARS,HDC,IDO1,LPCAT3,LPCAT4,MAT2A,MSRA,MTHFD1,MTHFD2L,MTRR,NARS,NIT2,NMNAT3,NOS3,NOX4,OAZ1,OAZ2,P4HA1,PCBD1,PCYOX1,PHYKPL,PLA2G10,PLA2G4B,PLA2G5,PRDX4,PSAT1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTDSS1,PTS,PYCR1,QDPR,RARS,RARS2,SERINC3,SHMT2,SLC1A3,SLC25A32,SLC5A5,SLC6A6,SLC7A2,TYMS,WARS,WARS2 97.38 0.02036 0.277102550724638 GO:0021591 ventricular system development biological_process 26 10 ARMC4,DPCD,HYDIN,MNAT1,MYH10,NME5,RAPGEF2,SEMA6D,TTC21B,UCHL5 5.1 0.02046 0.277658757225434 GO:0051294 establishment of spindle orientation biological_process 26 10 ARHGEF2,CENPA,CLASP1,LLGL2,NDE1,PAFAH1B1,SPAG5,SPDL1,SPRY1,WDR43 5.1 0.02046 0.277658757225434 GO:0072528 pyrimidine-containing compound biosynthe... biological_process 41 14 CMPK1,CPS1,DCTD,DTYMK,MTOR,NME4,NME5,NME6,NME7,NME9,TBPL1,TK1,TYMS,UPRT 8.05 0.02066 0.279968340548341 GO:0044030 regulation of DNA methylation biological_process 19 8 BRCA1,GRHL2,GSK3B,KDM1B,MBD3,PIK3CA,PRMT5,RLF 3.73 0.02087 0.281864734576758 GO:0048025 negative regulation of mRNA splicing, vi... biological_process 19 8 C1QBP,HNRNPA2B1,HNRNPK,RBMX,RNPS1,SAP18,SRSF7,TRA2B 3.73 0.02087 0.281864734576758 GO:0031589 cell-substrate adhesion biological_process 302 74 ACTN1,AKIP1,ALOX15,ANGPT2,ANGPTL3,ANTXR1,ARHGAP6,ATXN3,BCAS3,BCL2,BRAF,C1QBP,CASK,CCDC80,CCL25,CD44,CDC42,CDH13,CLASP1,CLASP2,COL17A1,DAG1,DAPK3,DDR1,EGFLAM,FBLN2,FBLN5,FMN1,GSK3B,HOXA7,ITGA2,ITGA6,ITGA7,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,JAM3,KANK1,MINK1,MKLN1,MUC4,MYO1G,MYOC,NF1,ONECUT2,PARVG,PEAK1,PIK3CB,PIP5K1A,PPFIA2,PRKCZ,PTEN,PTK2,PTK2B,PTPRK,PXN,RAB1A,RAC2,RADIL,RELL2,SNED1,SORBS3,STRC,THY1,TIMM10B,TRIOBP,TRIP6,TRPM7,TTYH1,VEGFA,ZYX 59.29 0.02092 0.281864734576758 GO:0001578 microtubule bundle formation biological_process 73 22 ARMC4,BBS2,CCDC114,CFAP100,CFAP46,CFAP73,CLASP1,CLIP1,DNAI1,DNAI2,DRC1,FES,IQCG,MAP1S,MAP2,PRC1,RSPH9,SPAG16,TPGS1,TPPP3,UBE2B,ZNF207 14.33 0.02092 0.281864734576758 GO:0090090 negative regulation of canonical Wnt sig... biological_process 163 43 AMER1,ANKRD6,CTNND1,CUL3,CYLD,DAB2IP,FZD6,GLI1,GPC3,GSK3B,HDAC1,IGFBP2,JADE1,LIMD1,LRP6,LZTS2,NKD1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SCYL2,SDHAF2,UBA52,WNT11,WWTR1 32 0.02146 0.288726160458453 GO:0051784 negative regulation of nuclear division biological_process 49 16 BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,HORMAD1,LCMT1,LIF,MTBP,NME6,PSMG2,TEX14,TOM1L1,TTK,XRCC3,ZNF207 9.62 0.02157 0.289779428571429 GO:0048523 negative regulation of cellular process biological_process 4089 848 ABAT,ABCA5,ABCE1,ABI1,ABR,ACADVL,ACOD1,ACOT8,ACTN1,ADA,ADAM10,ADAM22,ADAMDEC1,ADCYAP1,ADIPOR1,ADIPOR2,ADNP,ADORA1,AEBP1,AGO1,AGO2,AHR,AIPL1,AKT1,AMBRA1,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANK2,ANKLE2,ANKRD6,ANTXR1,ANXA2,ANXA4,APBB1,APBB2,APLP1,APOBEC3B,APOBEC3F,ARF1,ARHGAP4,ARHGAP6,ARHGEF1,ARHGEF15,ARHGEF2,ARID2,ARID4A,ARPP19,ASH1L,ASIC2,ASNS,ATAD1,ATF2,ATF4,ATF7IP,ATG3,ATOH8,ATP2B4,ATP5B,ATR,ATRAID,ATRX,ATXN2,ATXN7,AURKA,AURKB,BAG4,BAHCC1,BAP1,BAX,BAZ2A,BCAS3,BCHE,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLK,BNIP2,BPIFB1,BPTF,BRAF,BRCA1,BRD7,BRINP1,BRINP2,BRIP1,BTBD10,BTG3,BUB1B,C16orf45,C1D,C1QBP,C3orf33,C4A,C4B,C5AR2,CACNA1A,CACNA1C,CALM1,CAMSAP3,CAPRIN1,CAPZA1,CARD16,CARMIL2,CASK,CASP8,CBX5,CCNE2,CCNT1,CD14,CD200,CD2BP2,CD44,CD46,CD74,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC6,CDH1,CDH13,CDK5RAP3,CDK7,CDKN3,CEACAM5,CENPJ,CEP192,CEP63,CERS2,CFLAR,CHAD,CHCHD3,CHD7,CHFR,CHL1,CHORDC1,CHRD,CIART,CIR1,CLASP1,CLASP2,CLDN7,CLEC5A,CLK2,CLN3,CLN8,CLTA,CLU,CNOT2,CNOT7,CNOT8,CNST,COL4A3,COPS2,CPEB1,CPEB3,CPNE1,CR1,CRBN,CREM,CRHBP,CRYAB,CRYM,CSF1R,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,CTC1,CTDSPL2,CTNNA1,CTNND1,CTR9,CTTNBP2NL,CUL1,CUL3,CUX1,CXCL12,CXCR2,CXXC4,CYLD,CYP19A1,DAB2IP,DAD1,DAG1,DAPK1,DAPK3,DAPL1,DCBLD2,DCC,DDB1,DDIAS,DDIT4L,DDR1,DDX20,DDX39B,DDX6,DEPDC1,DHRS2,DICER1,DLG2,DLG3,DNA2,DNAJA1,DNAJC1,DNAJC10,DNM3,DOT1L,DPH3,DPPA4,DR1,DTX1,DUSP16,DUSP9,DYNC1LI1,DYRK2,E2F7,EAF2,EAPP,EGF,EGFL7,EGFR,EHMT1,EHMT2,EI24,EIF2AK2,EIF4A2,EIF4E,EIF4G2,EIF6,ELF1,ELF3,ELP2,EML2,EN1,ENY2,EPHA4,EPHB2,EPRS,ERN2,ERO1A,ESR1,ETV6,ETV7,EVL,EYA3,EYA4,EZH2,FADD,FAF1,FAM111A,FANCD2,FANCI,FARP1,FAS,FBN1,FBXO7,FBXW11,FGF12,FGFR1,FGFR1OP,FHL1,FHOD3,FIGNL1,FKBP4,FKBP8,FMN2,FOXJ1,FOXN3,FUOM,FXR1,FZD6,FZR1,GABBR1,GABRA5,GAK,GATAD2A,GATAD2B,GCLC,GCLM,GCSAM,GDF9,GEN1,GFRA2,GIGYF2,GIPR,GLA,GLI1,GMFB,GMFG,GNG4,GORASP1,GPC1,GPC3,GPR35,GRB10,GRB7,GRHL2,GRID2IP,GRM7,GRM8,GSK3B,GSN,GSTP1,GTF2H2,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELB,HELLS,HESX1,HEYL,HGS,HHATL,HIPK3,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPU,HORMAD1,HOXA7,HOXA9,HSF4,HSP90B1,HSPA8,HSPD1,HTR2B,HUS1,HYAL1,IDO1,IFRD1,IGF1R,IGF2BP3,IGFBP2,IL15,IL18BP,IL1B,IL1R2,IL2RA,IL4R,IMPACT,IP6K2,IQCB1,IRAK1,IRF2,ITGA6,ITGAV,ITGB1BP1,ITM2C,ITPR1,JADE1,JAZF1,JUND,KANK1,KANK2,KAT2B,KAT6A,KCNB1,KEL,KLF16,KLHL20,KLHL40,KLK8,KMT2A,KMT2D,KMT2E,KNTC1,KRAS,KRIT1,KRT16,L3MBTL1,LAMTOR1,LAMTOR3,LANCL2,LBX1,LCMT1,LEO1,LGR4,LHX9,LIF,LIG3,LIG4,LIMD1,LIMK1,LIMS2,LITAF,LMO3,LRP6,LRPPRC,LRRTM1,LRRTM3,LTA,LTBP1,LTF,LYPLA1,LZTS2,MAEA,MAGED1,MALSU1,MALT1,MAP2K4,MAP2K5,MAP3K12,MAP6D1,MAPK8,MAPKAPK5,MARCH5,MARVELD3,MASTL,MBD3,MDM1,MDM2,MDM4,MED14,MED21,MED24,MED30,MED31,MEF2A,MEF2C,MEIS2,METTL14,MGRN1,MIA3,MID1IP1,MIDN,MIER1,MLF1,MLX,MMP28,MMRN2,MNAT1,MORF4L1,MOSPD1,MPHOSPH10,MSX2,MTA3,MTBP,MTDH,MTF2,MTOR,MVP,MXD3,MYB,MYF6,MYO16,MYO18A,MYOC,N4BP1,NAA16,NAB1,NAE1,NAT10,NCK1,NCOA2,NCOR1,NCOR2,NDRG2,NEDD4L,NEK11,NEPRO,NF1,NFATC1,NFE2L2,NFE2L3,NFKBID,NIPBL,NISCH,NKD1,NKRF,NLGN3,NLRC5,NLRP12,NME6,NMI,NOS3,NOX4 802.83 0.02160 0.289779428571429 GO:0009060 aerobic respiration biological_process 57 18 COX20,CS,DLAT,DLD,MDH1,MT-CO1,MT-CO3,MTFR1,NNT,PDHB,PMPCB,SDHC,SDHD,SUCLG1,SURF1,UQCRB,UQCRC2,UQCRH 11.19 0.02178 0.291777432239658 GO:0006261 DNA-dependent DNA replication biological_process 137 37 ATRX,BAZ1A,CCNE2,CDC6,DNA2,E2F7,HELB,INO80,LIG3,LIG4,MCM2,MCMBP,MMS22L,NUCKS1,ORC4,PARP2,PNKP,POLA1,POLA2,POLB,POLD3,POLD4,PRIM1,PURA,RFC2,RFC4,RRM2B,SENP2,SLF1,SMC1A,TEFM,THOC1,TOP2B,TOPBP1,WIZ,WRN,ZRANB3 26.9 0.02200 0.294304843304843 GO:0051225 spindle assembly biological_process 90 26 AURKA,AURKB,BIRC3,BIRC7,CEP192,CEP63,CHMP3,CHMP5,CLASP1,FAM175B,HAUS3,INO80,KIF23,LZTS2,MAP9,NCOR1,NEK7,OFD1,RACGAP1,RNF4,SENP6,TNKS,TUBB8,TUBGCP5,XIAP,ZNF207 17.67 0.02214 0.295756386913229 GO:0006732 coenzyme metabolic process biological_process 280 69 ACACA,ACAT1,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,ADPGK,AGK,ALDH1L1,AMD1,ATIC,COASY,COQ4,CROT,DCXR,DHFR,DLAT,DLD,EIF6,ELOVL6,ELOVL7,ENO4,FAR1,FLAD1,FTCD,GART,GGH,HACD1,HSD17B4,KCNAB2,MAT2A,MDH1,MOCS1,MTHFD1,MTHFD2L,MTRR,NADK,NADSYN1,NCOR1,NDUFA9,NMNAT3,NMRK1,NNT,NOX1,OGT,PANK1,PANK3,PANK4,PCBD1,PCK2,PDHB,PDK3,PDSS1,PDXK,PFKFB1,PPCDC,PPT2,PTS,QDPR,SCD5,SHMT2,SIRT6,SLC25A32,SUCLG1,TECR,TIGAR,TPI1,TYMS 54.98 0.02220 0.296136647727273 GO:0031099 regeneration biological_process 159 42 ANGPT2,ATIC,AURKA,BCL2,BRAF,CERS2,CFLAR,CHL1,CPQ,CTNNA1,CXCL12,DHFR,EGFR,EPHA4,EZH2,GLI1,GSTP1,IFRD1,IGF2R,JAM3,KLK8,LCP1,LPIN1,MKI67,MYF6,NREP,NTRK3,PAX7,PFKFB1,PRMT5,PRRX1,PTEN,RAP1A,RGMA,RGN,RPL32,RTN4RL2,SRSF5,TGFB1,TYMS,UGT1A1,WNT10B 31.22 0.02234 0.297581475177305 GO:0042775 mitochondrial ATP synthesis coupled elec... biological_process 86 25 COX5A,COX6A1,COX7A2L,DLD,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHAF2,SDHC,TAZ,UQCRB,UQCRC2,UQCRH 16.89 0.02274 0.302480651558074 GO:0031344 regulation of cell projection organizati... biological_process 484 113 ADCYAP1,ADNP,AKT1,APBB1,ARF1,ARHGAP4,ARHGEF1,BCAS3,BRAF,CACNA1A,CAPRIN1,CARMIL2,CCDC88A,CDC42,CDC42EP3,CERS2,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CUX1,CXCL12,DAB2IP,DCC,DDX56,DNM3,ENPP2,EPHA4,EPHB2,EPS8L1,EVL,EZH2,FAM110C,FAM150A,FBXO7,FES,FEZ1,FGFR1,FKBP4,FNBP1L,GAK,GOLGA4,GORASP1,GPM6A,GPRC5B,GSK3B,HDAC2,IFRD1,ITGA2,ITM2C,KALRN,KANK1,KEL,KLK8,LIMK1,MDM2,MEF2C,METRN,MOB2,MTOR,MYO10,NCK1,NCKIPSD,NFE2L2,NLGN3,NTRK2,NTRK3,OLFM1,OPA1,PAFAH1B1,PAK3,PAQR3,PFN2,PLD1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRRX1,PTEN,PTK2,PTK2B,RAB5A,RAC2,RAP1A,RAP1GAP2,RAPGEF2,RELN,RGMA,RNF6,ROBO1,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SH3YL1,SHTN1,SKIL,SNAPIN,STK25,TAPT1,TGFBR1,THY1,ULK2,USH1C,VEGFA,VIL1 95.03 0.02286 0.30364676096181 GO:0007005 mitochondrion organization biological_process 531 123 AGTPBP1,AIP,AKT1,APOO,ATG3,ATG4B,ATP5B,ATPAF1,BAX,BBC3,BCL2,BOK,C12orf65,C1QBP,CASP8,CEP89,CHCHD3,CLU,COA1,COX17,COX20,CXADR,DAP3,DARS2,DNA2,DNM1L,DNM3,ELAC2,FBXO7,GABPB1,GCLC,GCLM,GGCT,GSK3B,HARS,HSPD1,IMMP2L,LIG3,LRPPRC,MALSU1,MAN2A1,MAPK8,MARCH5,MEF2A,MFF,MFN1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MSTO1,MTFR1,MTG1,MTIF2,MTIF3,MT-ND4,MTO1,MTRF1,MTRF1L,MTX1,MTX2,MTX3,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFAF7,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NMT1,NOS3,NSUN4,OMA1,OPA1,PDCD5,PDE2A,PNPT1,PTCD3,RARS2,RHOT1,RRM2B,SEPT4,SLC25A36,SLC25A46,SPATA18,SPG7,SSBP1,SURF1,TAZ,TEFM,TFB1M,TIGAR,TIMM10B,TIMM23B,TIMM50,TMEM70,TOMM20,TP63,TRMT10C,TTC19,UQCRB,VPS13C,WDR45B,YWHAQ,YWHAZ 104.26 0.02295 0.304411652542373 GO:0022904 respiratory electron transport chain biological_process 103 29 COX5A,COX6A1,COX7A2L,DLD,ETFA,IMMP2L,LYRM5,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHAF2,SDHC,SLC25A13,TAZ,UQCRB,UQCRC2,UQCRH 20.22 0.02311 0.306101565585331 GO:0009165 nucleotide biosynthetic process biological_process 322 78 ACACA,ACAT1,ADA,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADK,ADNP,AK2,AK6,AKAP12,AMDHD2,AMPD3,APLP1,APRT,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CALM1,CMPK1,COASY,DCTD,DHFR,DTYMK,FLAD1,GABBR1,GARS,GART,GBAS,GIPR,GMPS,GNPDA2,GRM7,GRM8,GUK1,HPRT1,HTR2B,IMPDH1,MT-ATP6,MTHFD1,MTHFD2L,NADK,NADSYN1,NAGK,NF1,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NOS3,OPRM1,PANK1,PANK3,PANK4,PDE2A,PDZD3,PGM3,PPCDC,PTK2B,RRM2B,SLC25A13,SURF1,TBPL1,TGFB1,TK1,TSHR,TYMS,UGDH,UGP2,UPRT 63.22 0.02357 0.311580436005626 GO:0010212 response to ionizing radiation biological_process 142 38 ATR,BAX,BCL2,BRCA1,CLK2,CRYAB,DMC1,ECT2,EEF1D,EYA3,FANCD2,FIGNL1,GTF2H5,HMGA2,HUS1,INO80,LIG4,MTA1,NIPBL,NOX4,NUCKS1,POLB,RAD51AP1,RAD51C,RAD54L,RFWD3,RNF8,STAR,TANK,TGFB1,TIGAR,TLK2,TOPBP1,TP63,WRN,XRCC3,XRCC5,XRRA1 27.88 0.02359 0.311580436005626 GO:0007266 Rho protein signal transduction biological_process 164 43 ABR,ARHGAP4,ARHGAP5,ARHGAP6,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CDC42EP3,CDH13,CELSR1,CHUK,CUL3,ECT2,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,GNA12,GPR35,HACD3,ITSN2,KALRN,KANK1,LIMK1,MCF2,MCF2L,MYOC,P2RY8,PDCD10,PDGFRB,PLEKHG2,PLEKHG6,ROBO1,SCAI,SHTN1,SOS1,SPATA13,TRIO,VAV1 32.2 0.02371 0.312725575842697 GO:0010972 negative regulation of G2/M transition o... biological_process 34 12 CDC6,CDK5RAP3,DNA2,FANCI,FHL1,FOXN3,HMGA2,HUS1,NAE1,RAD17,SLF1,TOPBP1 6.68 0.02386 0.313208212290503 GO:1902750 negative regulation of cell cycle G2/M p... biological_process 34 12 CDC6,CDK5RAP3,DNA2,FANCI,FHL1,FOXN3,HMGA2,HUS1,NAE1,RAD17,SLF1,TOPBP1 6.68 0.02386 0.313208212290503 GO:1903312 negative regulation of mRNA metabolic pr... biological_process 34 12 BAG4,C1QBP,CCNT1,CTR9,HNRNPA2B1,HNRNPK,PABPC1,RBMX,RNPS1,SAP18,SRSF7,TRA2B 6.68 0.02386 0.313208212290503 GO:0043149 stress fiber assembly biological_process 78 23 ARHGAP6,ARHGEF15,BAG4,BRAF,CLASP1,CLASP2,CUL3,EVL,ITGB1BP1,LIMK1,MTOR,MYOC,NOX4,PAK1,PDCD10,PFN2,PTK2B,SORBS3,SYNPO,TGFBR1,TMEFF2,WNT11,ZYX 15.31 0.02388 0.313208212290503 GO:0044087 regulation of cellular component biogene... biological_process 707 160 ACTR2,ACTR3C,ADNP,ALOX15,AMBRA1,ANKRD53,ANTXR1,ARF1,ARHGAP6,ARHGEF15,ARPC1A,ARPC1B,ASIC2,ATAT1,ATF7IP,ATXN2,BAG4,BAX,BCAS3,BCLAF1,BLK,BRAF,BRCA1,CAND1,CAPZA1,CARMIL2,CDC42,CDC42EP3,CENPJ,CHMP3,CHMP5,CLASP1,CLASP2,CLDN7,CLIP1,CLU,CNOT2,COBL,CRBN,CUL4B,CYFIP1,DAB2IP,DAPK3,DCTN1,DDB1,DNM1L,DNM3,EIF2AK2,EML2,EPHB2,EPS8L1,EVL,FAF1,FAM110C,FARP2,FAS,FBLIM1,FCHSD1,FES,FHOD3,FKBP4,FMN1,FNBP1L,GBP5,GMFB,GMFG,GPM6A,GSK3B,GSN,GTF2H2,GTF2H3,GTF2H5,HDAC6,HSPA8,HYAL1,ICE1,IMPACT,ITGB1BP1,KANK1,LCMT1,LCP1,LIMK1,LRRTM1,LRRTM3,MALSU1,MDM1,MEF2C,MTOR,MYO10,MYOC,NCK1,NECTIN1,NLGN3,NOX4,NPRL3,NRXN1,NSMAF,NTRK2,NTRK3,ORMDL2,ORMDL3,PAK1,PAK3,PAN3,PARP10,PFN2,PICK1,PKP2,PLD1,PLK4,PRKCZ,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTEN,PTK2,PTK2B,RAB3GAP2,RAB5A,RAC2,RALB,RAP1A,RAP1B,RAPGEF2,RNF4,RPA3,SEC24B,SENP6,SH3YL1,SIRT2,SIX1,SLAIN2,SLF1,SNX9,SORBS3,SORL1,SPTB,SPTBN1,SPTBN4,SUMO1,SYNPO,SYNPO2,TAPT1,TBX20,TFIP11,TGFB1,TGFBR1,TMC8,TMEFF2,TRAPPC12,TRIOBP,TWF1,VEGFA,VIL1,VPS11,WNT10B,WNT11,ZNF451 138.81 0.02401 0.314377382271468 GO:0006544 glycine metabolic process biological_process 16 7 AMT,DHFR,GART,GCAT,GCSH,SHMT2,SLC25A32 3.14 0.02417 0.314377382271468 GO:0007026 negative regulation of microtubule depol... biological_process 16 7 ARHGEF2,C16orf45,CLASP1,CLASP2,HDAC6,MAP6D1,MID1IP1 3.14 0.02417 0.314377382271468 GO:0009200 deoxyribonucleoside triphosphate metabol... biological_process 16 7 ADA,ADK,DTYMK,GUK1,RRM2B,TBPL1,TYMS 3.14 0.02417 0.314377382271468 GO:0051383 kinetochore organization biological_process 16 7 CENPA,CENPC,RNF4,SENP6,SMC2,SMC4,TRAPPC12 3.14 0.02417 0.314377382271468 GO:1900745 positive regulation of p38MAPK cascade biological_process 16 7 GADD45G,MAP3K3,OPRK1,PRMT1,SASH1,VEGFA,ZC3H12A 3.14 0.02417 0.314377382271468 GO:0001539 cilium or flagellum-dependent cell motil... biological_process 23 9 BBS2,CFAP20,CFAP46,DNAH17,DNAH2,DNAH3,DRC1,RSPH9,SPAG16 4.52 0.02435 0.315408068965517 GO:0032786 positive regulation of DNA-templated tra... biological_process 23 9 BRD4,CTR9,DDX39B,EAPP,HMGN1,LEO1,SUPT4H1,TCEB1,THOC1 4.52 0.02435 0.315408068965517 GO:0033119 negative regulation of RNA splicing biological_process 23 9 C1QBP,HNRNPA2B1,HNRNPK,PTBP2,RBMX,RNPS1,SAP18,SRSF7,TRA2B 4.52 0.02435 0.315408068965517 GO:2001252 positive regulation of chromosome organi... biological_process 138 37 ATR,ATRX,AURKB,BRCA1,BRD7,CCT3,CCT7,CHTOP,CTBP1,CTR9,CUL3,H2AFY,IL1B,KMT2A,LIF,LIG4,MAP2K7,MAPKAPK5,MIER1,MTF2,MYB,NEK7,NIPBL,NSMCE2,OGT,PAX7,PAXBP1,PHF1,PNKP,POT1,SFPQ,SLF1,SMAD4,TCP1,TGFB1,TNKS,VEGFA 27.09 0.02453 0.31730196969697 GO:0001510 RNA methylation biological_process 66 20 CMTR2,DIMT1,FBL,METTL1,METTL14,METTL15,METTL16,MTO1,NOP2,NSUN4,RRNAD1,TARBP1,TFB1M,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,WTAP 12.96 0.02532 0.322620239680426 GO:0009966 regulation of signal transduction biological_process 2553 538 AAK1,ABR,ACOD1,ADA,ADCYAP1,ADIPOR1,ADORA1,AGO1,AIP,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKR1B1,AKT1,ALOX15,AMER1,AMER3,ANKRD10,ANKRD6,ANXA2,ARAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL2BP,ARL6,ASH1L,ATP2B4,ATP2C1,ATP6V1C2,ATR,ATXN7,AURKA,AURKB,BAG4,BANP,BAX,BBC3,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLNK,BOK,BPIFB1,BRAF,BRCA1,BRD4,BRD7,BRIP1,BUD31,C1QBP,C3orf33,C5AR2,CALM1,CASP8,CCL25,CD14,CD44,CD46,CD74,CD81,CDC42,CDH13,CDK12,CDK5RAP3,CDON,CFLAR,CHAD,CHD3,CHN1,CHRD,CHRNA7,CHUK,CLTA,CNGA1,CNIH2,CNOT2,CPNE1,CRHBP,CSF1R,CSNK2A1,CSNK2A2,CTDNEP1,CTDSPL2,CTNNA1,CTNND1,CUL3,CXXC4,CYLD,CYTH4,DAB2IP,DAG1,DAPK1,DAPK3,DDIT4L,DNA2,DNAJA1,DNM1L,DOT1L,DTX1,DUSP16,DUSP9,DYRK2,ECT2,EEF1D,EGF,EGFL7,EGFR,EHMT1,EHMT2,EIF2A,EIF2AK2,ELF1,ELP2,EPHA4,EPS8L1,ESR1,EYA3,EYA4,EZH2,FADD,FAF1,FAM110C,FAM13B,FAM150A,FAM58A,FANCA,FANCD2,FARP1,FARP2,FAS,FBN1,FBXW11,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FKBP8,FNTA,FRS2,FZD6,GADD45G,GALNT11,GCLC,GCLM,GCSAM,GDF9,GDI2,GIPR,GLI1,GLRX2,GMIP,GNA12,GNG4,GNG7,GNGT1,GPC1,GPC3,GPR35,GPRC5B,GPSM1,GRAP,GRB10,GRB7,GRK6,GSK3B,GSN,GSTP1,GTF2H2,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HEYL,HGS,HIPK3,HTR2B,HUS1,IGF1R,IGFBP2,IL15,IL18BP,IL1B,IL1R2,IL22RA2,INPP5B,IRAK1,IRAK4,ITGA6,ITGAV,ITGB1BP1,ITM2C,ITPR1,ITSN2,JADE1,KALRN,KANK1,KANK2,KAT6A,KLHL24,KMT2D,KRAS,L3MBTL1,LAMTOR1,LAMTOR3,LANCL2,LAT,LDLRAP1,LFNG,LGR4,LGR5,LIF,LIMD1,LIMS2,LITAF,LLGL2,LMO3,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,LYNX1,LZTS2,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARVELD3,MBD3,MBD5,MCF2,MCF2L,MDM2,MDM4,MEAF6,MED16,MEF2C,METAP2,MFF,MFNG,MGRN1,MIER1,MINK1,MKS1,MMRN2,MST1R,MSX2,MTCH1,MTDH,MTOR,MYOC,NCK1,NCOA1,NCOA2,NCOR1,NDRG2,NEK10,NEPRO,NF1,NFATC1,NFKBID,NKD1,NLGN3,NLRC5,NLRP12,NMT1,NOX1,NOX4,NPRL3,NR2C1,NREP,NTRK2,NTRK3,NUCKS1,OCRL,OGT,ONECUT2,OPA1,OPRK1,OPRM1,OSBPL8,OTULIN,P2RX5,P2RY8,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PAWR,PBK,PDCD10,PDCD5,PDE4D,PDE5A,PDE6B,PDGFRB,PEAR1,PELI1,PEX5L,PHF14,PHF20,PHIP,PIAS1,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R5,PIN1,PIP5K1A,PIP5K1C,PLA2G5,PLCB1,PLEKHG2,PLEKHG6,PLK3,PLXNB1,PODN,POGLUT1,POR,PPM1B,PPP1R2P3,PPP2R1A,PPP2R5C,PRDM16,PRICKLE1,PRKCZ,PRLR,PRMT1,PRMT5,PRR5L,PRRX1,PSD3,PSD4,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPN13,PTPN2,PTPN6,PTTG1IP,PUM2,PXDN,PXN,RAC2,RACGAP1,RAD17,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAPGEF2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP4,RBBP4,RBBP7,RBBP8,RBCK1,RBPJ,RBPMS,RELN,RELT,RFC2,RFC4,RGN,RGS14,RGS3,RGS6,RHOC,RHOF,RHOT1,RIC8B,RMI1,RNF14,RNF220,RNF43,RNF6,ROBO1,ROS1,RPA3,RPS6KA6,RPS6KB1,RRAGB,RTN4RL2,SASH1,SCAI,SCYL2,SDCBP,SDHAF2,SEC14L1,SEH1L,SEMA4D,SEMA7A,SENP2,SEPT4,SERPINA12,SGSM3,SH2B3,SH2D3C,SHC2,SHE,SIPA1,SIX3,SKIL,SLC38A9,SMAD2,SMAD4,SMYD2,SORBS3,SORL1,SOS1,SPAG9,SPATA13,SPRY1,SSX2IP,STAM,STAMBP,STAP2,STK25,STRAP,SUMO1,TAB2,TAB3,TAF2,TANK,TAX1BP1,TBC1D10C,TBK1,TBX20,TELO2,TGFA,TGFB1,TGFB1I1,TGFBR1,THY1,TLR7,TLR9,TMBIM4,TMBIM6,TMEM237,TNFRSF10B,TNFRSF19,TNFRSF25,TNFSF12,TNKS 501.25 0.02533 0.322620239680426 GO:0048863 stem cell differentiation biological_process 374 89 ACE,ADIPOR1,AMER1,BCHE,BCL2,BRAF,CDON,CHD2,CLASP1,CLASP2,CNOT2,CTR9,DAB2IP,DAG1,DDX6,DPPA4,EIF4E,EZH2,FANCD2,FGFR1,GPM6A,GSK3B,HDAC2,HEYL,HMGA2,HOXA7,HTR2B,LEO1,LIF,LIG4,LRP6,LTBP3,MED14,MED21,MED24,MED30,MEF2C,MEGF10,METTL14,MSI2,MSX2,MTF2,NIPBL,OLFM1,PAX2,PAX3,PAX7,PBX1,PCM1,PHLDB1,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PRDM16,PRICKLE1,PRRX1,PSMD11,PWP1,RBPJ,RDH10,RIF1,RTN4,SDCBP,SDHAF2,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SIX3,SMAD2,SMAD4,SMC1A,SOX6,SS18,STRAP,TAPT1,TBX3,TGFB1,TGFB1I1,TGFBR1,TP63,WNT10A,WNT11,WWTR1,XRCC5,ZCCHC11 73.43 0.02555 0.322620239680426 GO:0043967 histone H4 acetylation biological_process 62 19 ACTL6A,APBB1,BRCA1,CTBP1,ELP4,HAT1,JADE1,KANSL1,KANSL1L,KANSL2,KAT7,KMT2A,MEAF6,MORF4L1,NAA60,NCOA1,OGT,PHF20,YEATS4 12.17 0.02567 0.322620239680426 GO:0000080 mitotic G1 phase biological_process 4 3 CDC6,MDM2,MTBP 0.79 0.02580 0.322620239680426 GO:0006235 dTTP biosynthetic process biological_process 4 3 DTYMK,TBPL1,TYMS 0.79 0.02580 0.322620239680426 GO:0007089 traversing start control point of mitoti... biological_process 4 3 CDC6,MDM2,MTBP 0.79 0.02580 0.322620239680426 GO:0009212 pyrimidine deoxyribonucleoside triphosph... biological_process 4 3 DTYMK,TBPL1,TYMS 0.79 0.02580 0.322620239680426 GO:0009256 10-formyltetrahydrofolate metabolic proc... biological_process 4 3 ALDH1L1,MTHFD1,MTHFD2L 0.79 0.02580 0.322620239680426 GO:0014042 positive regulation of neuron maturation biological_process 4 3 BCL2,MTOR,OPA1 0.79 0.02580 0.322620239680426 GO:0034316 negative regulation of Arp2/3 complex-me... biological_process 4 3 GMFB,GMFG,PICK1 0.79 0.02580 0.322620239680426 GO:0035087 siRNA loading onto RISC involved in RNA ... biological_process 4 3 AGO2,DICER1,TARBP2 0.79 0.02580 0.322620239680426 GO:0038065 collagen-activated signaling pathway biological_process 4 3 DDR1,DDR2,ITGA2 0.79 0.02580 0.322620239680426 GO:0043103 hypoxanthine salvage biological_process 4 3 ADA,CECR1,HPRT1 0.79 0.02580 0.322620239680426 GO:0046075 dTTP metabolic process biological_process 4 3 DTYMK,TBPL1,TYMS 0.79 0.02580 0.322620239680426 GO:0048296 regulation of isotype switching to IgA i... biological_process 4 3 TGFB1,THOC1,WHSC1 0.79 0.02580 0.322620239680426 GO:0048496 maintenance of organ identity biological_process 4 3 IQCB1,PKP2,USH2A 0.79 0.02580 0.322620239680426 GO:0051318 G1 phase biological_process 4 3 CDC6,MDM2,MTBP 0.79 0.02580 0.322620239680426 GO:0055118 negative regulation of cardiac muscle co... biological_process 4 3 ADORA1,PDE5A,ZC3H12A 0.79 0.02580 0.322620239680426 GO:0060282 positive regulation of oocyte developmen... biological_process 4 3 AURKA,PDE5A,SIRT2 0.79 0.02580 0.322620239680426 GO:0061086 negative regulation of histone H3-K27 me... biological_process 4 3 H2AFY,MTF2,PHF1 0.79 0.02580 0.322620239680426 GO:0071139 resolution of recombination intermediate... biological_process 4 3 GEN1,SMC6,XRCC3 0.79 0.02580 0.322620239680426 GO:1901896 positive regulation of calcium-transport... biological_process 4 3 RGN,RYR2,SUMO1 0.79 0.02580 0.322620239680426 GO:2000301 negative regulation of synaptic vesicle ... biological_process 4 3 BRAF,RAP1A,RAP1B 0.79 0.02580 0.322620239680426 GO:2001013 epithelial cell proliferation involved i... biological_process 4 3 LGR4,LGR5,MEF2C 0.79 0.02580 0.322620239680426 GO:0031334 positive regulation of protein complex a... biological_process 214 54 ACTR2,ACTR3C,ALOX15,ANKRD53,ARF1,ARPC1A,ARPC1B,ATAT1,BAG4,BAX,BCLAF1,CAND1,CDC42EP3,CLASP1,CLIP1,CUL4B,CYFIP1,DCTN1,DDB1,EVL,FAF1,FAS,FES,FMN1,GBP5,GMFB,GMFG,GSK3B,GSN,GTF2H2,GTF2H3,GTF2H5,HDAC6,ICE1,LCP1,MTOR,NCK1,PFN2,PICK1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTK2B,RPA3,SLAIN2,SLF1,SNX9,SUMO1,TGFB1,VEGFA,VIL1,WNT10B 42.02 0.02588 0.322652370860927 GO:0031102 neuron projection regeneration biological_process 46 15 BCL2,BRAF,CERS2,CHL1,CTNNA1,DHFR,EPHA4,JAM3,KLK8,NREP,NTRK3,PRRX1,PTEN,RGMA,RTN4RL2 9.03 0.02593 0.322652370860927 GO:0009145 purine nucleoside triphosphate biosynthe... biological_process 58 18 ADK,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,GBAS,IMPDH1,MT-ATP6,NME4,NME5,NME6,NME7,NME9,SLC25A13,SURF1,TGFB1 11.39 0.02594 0.322652370860927 GO:0071479 cellular response to ionizing radiation biological_process 58 18 ATR,CRYAB,ECT2,EEF1D,FIGNL1,GTF2H5,HMGA2,HUS1,INO80,NIPBL,NOX4,NUCKS1,RAD51AP1,TANK,TGFB1,TLK2,WRN,XRCC5 11.39 0.02594 0.322652370860927 GO:0032269 negative regulation of cellular protein ... biological_process 982 217 AGO1,AGO2,AKT1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANXA2,ARPP19,ASH1L,ATF4,BAG4,BAX,BIRC3,BIRC6,BIRC7,BRCA1,BUB1B,C3orf33,C4A,C4B,CALM1,CAMSAP3,CAPRIN1,CARD16,CASP8,CD2BP2,CD44,CDC23,CDC27,CDK5RAP3,CEP192,CHAD,CHORDC1,CLN3,CLN8,CNOT2,CNST,COL4A3,CPEB1,CPEB3,CR1,CRYAB,CSNK2A1,CSNK2A2,CSRNP3,CSTL1,CTBP1,DAB2IP,DAG1,DAPK1,DAPK3,DLG2,DLG3,DNAJA1,DNAJC1,DNAJC10,DUSP16,DUSP9,DYNC1LI1,EIF2AK2,EIF4E,EIF6,EPRS,FARP1,FBXO7,FGFR1OP,FXR1,FZR1,GCLC,GEN1,GFRA2,GIGYF2,GMFB,GMFG,GPC3,GRB7,GSTP1,H2AFY,HAP1,HDAC1,HDAC2,HDAC6,HDAC8,HHATL,HIPK3,HNRNPD,IGF1R,IGF2BP3,IL1B,IL1R2,IMPACT,ITGB1BP1,KAT2B,KLHL40,LCMT1,LIF,LIMK1,LMO3,LRP6,LRRTM1,LRRTM3,MALSU1,MAP2K5,MARVELD3,MASTL,MDM2,METTL14,MPHOSPH10,MTF2,MTOR,MVP,N4BP1,NCK1,NCOR1,NDRG2,NF1,NLRP12,NTRK3,OGT,OVOS2,PAFAH1B1,PAIP2,PAK2,PAQR3,PARP10,PAX2,PBK,PDCL3,PDE4D,PHF1,PIN1,PODN,POR,PPP1R1B,PPP2R1A,PRKAR2A,PRKCZ,PRMT3,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,PTEN,PTPN2,PTPN6,PURA,RBM4,RGN,RGS14,RGS3,RNF4,RPS6KA1,RPS6KA6,RTN4RL2,SDCBP,SEMA4D,SENP2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SIRT2,SMAD4,SMYD3,SORL1,SPINT2,SPOCK3,SPRY1,STRAP,SYTL2,TARBP2,TBC1D10C,TEX14,TFPI,TGFB1,THY1,TIA1,TLK2,TRIP12,TTK,UBA52,UBE2B,UBE2E1,UCHL5,UFL1,UNK,USP4,VEGFA,VIL1,WAC,WFDC2,WWTR1,XIAP,XRCC3,ZC3H12A,ZNF207,ZNF451 192.81 0.02599 0.32284667989418 GO:0042773 ATP synthesis coupled electron transport biological_process 87 25 COX5A,COX6A1,COX7A2L,DLD,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHAF2,SDHC,TAZ,UQCRB,UQCRC2,UQCRH 17.08 0.02613 0.324156974900925 GO:0048812 neuron projection morphogenesis biological_process 548 126 ABI1,ADNP,ANK3,APBB1,APBB2,ARHGAP4,ARHGEF1,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAPRIN1,CELSR2,CERS2,CHL1,CHN1,CHRNA3,COBL,CRTAC1,CSF1R,CTNNA1,CUX1,CXCL12,CYFIP1,DAB2IP,DAG1,DCC,DHFR,DICER1,DNM3,DOCK7,EGFR,EPB41L3,EPHA4,EPHB2,ETV1,EVL,FARP1,FEZ1,FEZ2,FMN1,GOLGA4,GORASP1,GPC1,GPM6A,GSK3B,HDAC6,HPRT1,IFRD1,JAM3,KALRN,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP1S,MAP2,MAP6,MAPK8IP3,MEF2A,METRN,MINK1,MYH10,NECTIN1,NLGN3,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OLFM1,PAFAH1B1,PAK1,PAK3,PAX2,PLA2G10,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRRX1,PTEN,PTK2,PTPRA,RAPGEF2,RAPH1,RELN,RGMA,RNF6,ROBO1,ROBO3,RTN4,RTN4RL2,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SGK1,SHTN1,SKIL,SLC11A2,SMAD4,SOS1,SPTB,SPTBN1,SPTBN4,STK25,SZT2,THY1,TLR9,TOP2B,ULK2,USP33,USP9X,VEGFA,WEE1,ZNF280D 107.59 0.02670 0.330791160949868 GO:1901522 positive regulation of transcription fro... biological_process 27 10 ATF4,CARF,CHD6,NCOA1,NFE2L2,RBPJ,RXRA,SMAD4,SMAD9,VEGFA 5.3 0.02691 0.332953636363636 GO:0034504 protein localization to nucleus biological_process 338 81 AKT1,ARL2BP,ASUN,BANP,CDH1,CDK5RAP3,CEP57,CSE1L,CTDNEP1,CYLD,DAB2IP,DAG1,DYRK2,ECT2,EGF,EGFR,FAF1,FBXW11,FYB,GSK3B,IL1B,IPO11,IPO8,IPO9,KANK1,KAT7,LIF,LITAF,LZTS2,MDM2,MTOR,NCKIPSD,NF1,NLRP12,NOP58,NUP107,NUP155,NUP205,NUP35,NUP50,NUP54,NUP58,NUP98,OSBPL8,PARP10,PDE2A,PIK3R2,PIN1,PLRG1,POLA2,PPM1B,PRICKLE1,PTTG1IP,RAE1,RANBP2,RANBP6,RBCK1,RBPMS,RPL23,SEC61B,SIX1,SIX3,SMAD4,SPRN,SPTBN1,SRI,SUMO1,SYNE1,TBC1D10C,TGFB1,TGFBR1,TLR7,TLR9,TNPO1,TOR1AIP1,TOR1AIP2,TRIM29,TRIP6,WWTR1,XPO1,ZC3H12A 66.36 0.02730 0.337311902887139 GO:0010629 negative regulation of gene expression biological_process 1459 315 AAAS,ACE,ACOD1,ADNP,AEBP1,AGO1,AGO2,AHR,AKT1,ANXA4,ANXA7,ARID4A,ATF2,ATF4,ATF7IP,ATOH8,ATRX,AURKB,BAHCC1,BAZ2A,BBS2,BCLAF1,BIRC3,BIRC7,BPTF,BRCA1,BRD7,C1D,C1QBP,CAPRIN1,CBX5,CCNT1,CD46,CDC42,CDK5RAP3,CHCHD3,CIART,CIR1,CNOT2,CNOT7,CNOT8,COPS2,CPEB1,CPEB3,CPNE1,CR1,CREM,CRYAB,CRYM,CTBP1,CTR9,CUL3,CUX1,CYLD,DAB2IP,DAPK1,DAPK3,DDX20,DEPDC1,DICER1,DOT1L,DR1,DROSHA,E2F7,EAPP,EHMT1,EHMT2,EIF2AK2,EIF4E,EIF6,ELF3,ELP2,EN1,EPRS,ERN2,ESR1,ETV6,ETV7,EXD1,EZH2,FBXW11,FGFR1,FKBP6,FOXJ1,FOXN3,FXR1,FZD6,GATAD2A,GATAD2B,GCLC,GIGYF2,GRB7,GZF1,H2AFV,H2AFY,HAP1,HAT1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HELLS,HESX1,HEYL,HIST2H2AC,HMGA2,HNRNPA2B1,HNRNPD,HNRNPK,HOXA7,HSF4,HSPA8,IGF2BP3,IL1R2,IMPACT,IPO8,IRAK1,IRF2,ITGB8,JAZF1,JUND,KANK2,KAT6A,KLF16,KMT2D,L3MBTL1,LANCL2,LGR4,LHX9,LIMD1,MAGED1,MALSU1,MAP2K5,MBD3,MDM2,MDM4,MEF2A,MEF2C,MEIS2,METTL14,MIER1,MLX,MORF4L1,MOSPD1,MSX2,MTA3,MTDH,MTF2,MXD3,MYB,MYF6,NAB1,NCBP2,NCOA2,NCOR1,NCOR2,NDC1,NEDD4L,NFE2L3,NFKBID,NIPBL,NKRF,NLRC5,NLRP12,NR2C1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OLFM1,OTULIN,PABPC1,PAIP2,PARP10,PAWR,PAX2,PAX4,PAXBP1,PCBP3,PDCD10,PDE2A,PELI1,PHF1,PHF12,PHF14,PIAS1,PIWIL4,PLA2G10,PLCB1,PLK3,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PRDM16,PRICKLE1,PRRX1,PSMC5,PTBP2,PTPRK,PTRH2,PUM2,PURA,RAE1,RANBP2,RBBP4,RBBP7,RBBP8,RBCK1,RBL1,RBM4,RBMX,RBPJ,RECQL5,RFX5,RNF2,RNF8,RNPS1,ROS1,RRP8,RUNX1T1,RXRA,SAP18,SEH1L,SEMA4D,SFPQ,SIM2,SIRT2,SIRT5,SIRT6,SIX1,SIX3,SKIL,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCE1,SMYD2,SNAI3,SORBS3,SOX6,SP3,SRSF7,STAT6,STRAP,SUMO1,SUPT4H1,TARBP2,TAX1BP1,TBK1,TBL1XR1,TBPL2,TBX20,TBX3,TCERG1,TCF25,TCF7,TGFB1,TGIF1,TIA1,TIPARP,TLR9,TNRC18,TP63,TRA2B,TRIM29,TSC22D3,UBA3,UBA52,UBE2B,UFL1,UNK,USP3,USP7,USP9X,VEGFA,WHSC1,WNT10B,WNT11,WWC2,WWP1,WWTR1,XIAP,XPO1,XRCC5,YBX3,YWHAQ,ZBTB20,ZC3H12A,ZC3H8,ZCCHC11,ZEB1,ZNF148,ZNF219,ZNF224,ZNF253,ZNF254,ZNF280D,ZNF418,ZNF431,ZNF451,ZNF613,ZNF706,ZNF91 286.46 0.02737 0.337311902887139 GO:0034612 response to tumor necrosis factor biological_process 260 64 ACOD1,ADAM10,AFF3,ARHGEF2,BAG4,BIRC3,BRCA1,CASP8,CCL25,CD14,CHUK,CRHBP,CYLD,DAB2IP,FAS,GSTP1,HDAC1,HYAL1,HYAL3,IL18BP,LTA,MADD,MAP2K7,NFE2L2,NUB1,OTULIN,PCK2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTK2B,PTPN2,RBCK1,RELT,RPS6KB1,TANK,TAX1BP1,TNFRSF10B,TNFRSF13B,TNFRSF19,TNFRSF25,TNFSF12,TRADD,TXNDC17,UBA52,YBX3,ZC3H12A 51.05 0.02737 0.337311902887139 GO:0040023 establishment of nucleus localization biological_process 13 6 CDC42,DCTN4,MYH10,PAFAH1B1,PTK2,WDR43 2.55 0.02753 0.338395589005236 GO:0097296 activation of cysteine-type endopeptidas... biological_process 13 6 BAX,CASP8,FADD,FAS,TNFRSF10B,TRADD 2.55 0.02753 0.338395589005236 GO:0048518 positive regulation of biological proces... biological_process 5331 1093 AAK1,ABAT,ABCB1,ABCB4,ABI1,ABLIM3,ABR,ACACA,ACAP1,ACAP2,ACE,ACIN1,ACOD1,ACSL1,ACTG1,ACTR2,ACTR3C,ADA,ADAM10,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADIPOR1,ADIPOR2,ADNP,ADORA1,ADPRHL1,AGFG1,AGO1,AGO2,AHR,AHSA2,AKAP12,AKNA,AKR1B1,AKT1,AKTIP,ALDH1A3,ALOX15,AMBRA1,AMER1,AMPH,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPT2,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD49,ANKRD53,ANKRD6,ANO6,ANXA2,AP1G1,APBB1,APBB2,APH1A,ARAP2,ARF1,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID4A,ARIH1,ARL1,ARL2BP,ARPC1A,ARPC1B,ARPP19,ASH1L,ASIC2,ASNS,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATG4B,ATMIN,ATOH8,ATP11C,ATP1B1,ATP2B4,ATP2C1,ATP6V1C2,ATR,ATRAID,ATRX,ATXN7,AURKA,AURKB,AZIN2,BAG4,BANP,BAX,BBC3,BBS2,BCAR1,BCAS3,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLK,BLNK,BMPR1B,BNIP2,BOC,BOK,BOLL,BPIFB1,BPTF,BRAF,BRCA1,BRD4,BRD7,BRINP1,BRINP2,BTBD10,BTK,BUB1B,BUD31,C12orf4,C14orf166,C1QBP,C1RL,C1S,C2,C2CD5,C4A,C4B,C5AR2,CACNA1H,CACNA2D1,CACNB3,CACUL1,CADPS2,CALCOCO2,CALM1,CAMK2A,CAMK2G,CAMTA1,CAND1,CAPRIN1,CARF,CARMIL2,CASK,CASP8,CCDC80,CCDC88A,CCDC88B,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CD14,CD247,CD3G,CD44,CD46,CD6,CD74,CD79B,CD81,CDC123,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDK13,CDK5RAP3,CDK7,CDON,CENPJ,CEP290,CFAP20,CFLAR,CHD1,CHD6,CHD7,CHFR,CHN1,CHRD,CHRNA3,CHRNA7,CHTOP,CHUK,CLASP1,CLASP2,CLDN7,CLEC4E,CLEC5A,CLIP1,CLU,CNOT2,CNOT7,CNOT8,CNST,CNTN1,COBL,COL4A3,COLEC11,CPEB3,CPNE1,CPNE3,CPS1,CR1,CRACR2A,CRCP,CREB5,CREM,CSF1R,CSNK2A1,CSNK2A3,CSPP1,CSRNP3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNA1,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CXCL12,CXCR2,CYBB,CYFIP1,CYLD,CYTH4,DAB2IP,DAPK1,DAPK3,DBF4,DCAF6,DCTN1,DCUN1D4,DDB1,DDR2,DDX20,DDX39B,DDX56,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DHFR,DIABLO,DICER1,DKKL1,DMBT1,DMRT2,DNA2,DNAJA1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DNM3,DOCK4,DOCK7,DOT1L,DPP10,DROSHA,DUOXA1,DUSP9,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,ECT2,EEF1D,EGF,EGFL7,EGFLAM,EGFR,EHD2,EIF2A,EIF2AK2,EIF4E,EIF6,ELF1,ELF3,ELMOD3,ELP5,ELP6,EN1,ENPP2,ENY2,EPHA4,EPHB2,EPS8L1,ERC1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,EVL,EXOC1,EXPH5,EYA3,EYA4,EZH2,FADD,FAF1,FAM110C,FAM13B,FAM150A,FAM58A,FANCI,FARP1,FARP2,FAS,FBLN2,FBXO22,FBXW11,FCER2,FES,FEZ1,FGD3,FGD4,FGD6,FGF12,FGF5,FGFR1,FGFR1OP,FHL1,FKBP6,FKBP8,FMN1,FNBP1,FNBP1L,FNTA,FOXJ1,FOXN3,FOXN4,FRS2,FUBP1,FXR1,FYB,FZR1,GABPB1,GADD45G,GBP5,GCGR,GCLC,GCLM,GCSAM,GDF9,GDI2,GEN1,GFRA2,GGA1,GIPR,GKN1,GLI1,GMFB,GMFG,GMIP,GOLGA4,GPBP1,GPBP1L1,GPC1,GPC3,GPIHBP1,GPM6A,GPR35,GPRC5B,GRAP,GRB10,GRB7,GRHL1,GRHL2,GSK3B,GSN,GSTP1,GTF2B,GTF2H2,GTF2H3,GTF2H5,H2AFY,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC9,HEATR1,HEXB,HEYL,HGS,HIVEP3,HLA-DMB,HLA-DPB1,HLTF,HMGA2,HMGN1,HNRNPD,HNRNPK,HNRNPU,HOXA10,HOXA7,HOXB1,HPRT1,HSF4,HSP90B1,HSPA8,HSPD1,HSPH1,HTR2B,HYAL1,ICE1,ICE2,IDO1,IFNL2,IGF1R,IGF2R,IGFBP2,IL15,IL1B,IL2RA,IL4R,IMPACT,INO80,INPP5B,IP6K2,IRAK1,IRAK4,IRF2,IRF5,ITGA2,ITGA6,ITGAV,ITGB1BP1,ITGB3BP,ITGB8,ITM2C,ITSN2,JADE1,JUND,KALRN,KANK1,KAT2B,KAT6A,KAT7,KCNB1,KCNMA1,KDM6A,KDM7A,KIAA1524,KIF23,KLF6,KMT2A,KMT2D,KMT2E,KRAS,LAMC2,LAMTOR1,LAMTOR3,LANCL2,LAT,LCP1,LDLRAP1 1046.69 0.02758 0.338567032679739 GO:0048667 cell morphogenesis involved in neuron di... biological_process 530 122 ABI1,ADNP,ANK3,APBB1,APBB2,ARHGAP4,ARHGEF1,BCL2,BMPR1B,BOC,BRAF,CACNA1A,CAMK2A,CAPRIN1,CELSR2,CERS2,CHL1,CHN1,CHRNA3,COBL,CRTAC1,CSF1R,CTNNA1,CUX1,CXCL12,CYFIP1,DAG1,DCC,DHFR,DNM3,DOCK7,EPHA4,EPHB2,ETV1,EVL,FARP1,FEZ1,FEZ2,FMN1,GOLGA4,GORASP1,GPC1,GSK3B,HDAC6,HPRT1,IFRD1,JAM3,KALRN,KEL,KLK8,KRAS,LGI1,LHX9,LIMK1,LINGO3,MAP2,MAP6,MAPK8IP3,MEF2A,MEF2C,METRN,MINK1,MYH10,NECTIN1,NLGN3,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OLFM1,PAFAH1B1,PAK1,PAK3,PAX2,PLA2G10,PLXNA1,PLXNB1,PLXNC1,PLXND1,PTEN,PTK2,PTPRA,RAPGEF2,RAPH1,RELN,RGMA,RNF6,ROBO1,ROBO3,RTN4,RTN4RL2,RUFY3,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SKIL,SLC11A2,SLC1A3,SMAD4,SOS1,SPTB,SPTBN1,SPTBN4,STK25,STRC,SZT2,THY1,TLR9,TOP2B,ULK2,UNK,USP33,USP9X,VEGFA,ZNF280D 104.06 0.02794 0.342538563968668 GO:0007265 Ras protein signal transduction biological_process 320 77 ABR,ARHGAP4,ARHGAP5,ARHGAP6,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CDC42EP3,CDH13,CELSR1,CHUK,CUL3,CYFIP1,CYTH4,DAB2IP,ECT2,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,GNA12,GPR35,GRAP,HACD3,HACE1,ITSN2,KALRN,KANK1,KRAS,LAT,LIMK1,MADD,MAPKAPK5,MCF2,MCF2L,MYOC,NF1,NISCH,NRAS,OGT,P2RY8,PDCD10,PDGFRB,PLD1,PLEKHG2,PLEKHG6,PSD3,PSD4,RALB,RAP1A,RAP1B,RAPGEF2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RIT1,ROBO1,RRAS2,SCAI,SDCBP,SGSM3,SHC2,SHTN1,SOS1,SPATA13,SPRY1,SSX2IP,STAMBP,TRIO,VAV1 62.83 0.02815 0.344336666666667 GO:0045216 cell-cell junction organization biological_process 206 52 ACTN1,ANK2,ARHGAP6,BCAS3,BCL2,CAMSAP3,CD9,CDC42,CDH1,CDH13,CDH8,CLASP1,CLASP2,CSF1R,CTNNA1,CTNND1,CXADR,DAPK3,DSG2,ECT2,EPB41L3,FBF1,FMN1,FRMPD2,GJB1,GNPAT,GRHL2,HDAC7,ITGA2,ITGB1BP1,KIFC3,LIMS2,MARVELD3,MTDH,MYOC,NECTIN1,PIP5K1A,PIP5K1C,PKP2,PKP4,PTEN,PTK2,PTK2B,PTPRK,RHOC,STRN,TGFB1,THY1,TLN1,TRIP6,VEGFA,WNT11 40.45 0.02816 0.344336666666667 GO:0045859 regulation of protein kinase activity biological_process 706 159 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,ATP2B4,BAX,BCCIP,BIRC7,BRAF,CACUL1,CALM1,CCDC88A,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CDK12,CDK5RAP3,CDK7,CDKN3,CHAD,CHORDC1,CHRNA3,CHRNA7,CSF1R,DAB2IP,DDR2,DNAJA1,DUSP16,DUSP9,ECT2,EGF,EGFR,EIF2AK2,ELP4,EPHA4,EZH2,FAF1,FAM150A,FAM58A,FBXO7,FGFR1,FGFR1OP,FRS2,GADD45G,GMFB,GMFG,GPRC5B,GSTP1,H2AFY,HACD3,HERC5,HGS,HIPK3,HSPH1,HTR2B,IGF1R,IL1B,IRAK1,ITGB1BP1,KAT2B,KRAS,LAMTOR3,LAT,LRP6,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MNAT1,MST1R,MTOR,MVP,NCK1,NEK10,NF1,NOX4,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PAQR3,PDCD10,PDE5A,PDGFRB,PIK3CA,PIK3CB,PIK3R5,PODN,PPP1R1B,PPP2R1A,PPP2R3C,PRKAR2A,PRKCZ,PRLR,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RAP1A,RAPGEF2,RELN,RGN,RGS14,RGS3,RTN4RL2,SASH1,SHC2,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPRY1,TAB2,TAB3,TARBP2,TELO2,TGFA,TGFB1,TGFBR1,THY1,TLR9,TNFRSF10B,TOM1L1,TRAF4,UBA52,UVRAG,VEGFA,WNT11,WWTR1,ZP4 138.62 0.02851 0.346367798982188 GO:0032479 regulation of type I interferon producti... biological_process 109 30 ACOD1,CD14,CRCP,CYLD,HAVCR2,HERC5,HSPD1,IRAK1,IRF5,NLRC5,NMI,PCBP2,PIN1,POLR1D,POLR2E,POLR2H,POLR2K,POLR3C,POLR3F,PPM1B,RNF216,STAT6,TAX1BP1,TBK1,TLR7,TLR9,TRIM38,UBA52,XRCC5,ZBTB20 21.4 0.02855 0.346367798982188 GO:0050685 positive regulation of mRNA processing biological_process 31 11 AGO2,CNOT7,CPEB3,HSPA8,LEO1,NCBP2,PABPC1,POLR2G,RBMX,THRAP3,TRA2B 6.09 0.02874 0.346367798982188 GO:0070059 intrinsic apoptotic signaling pathway in... biological_process 31 11 ATF4,BAX,BCL2,CASP4,DAB2IP,DNAJC10,ERO1A,GSK3B,ITPR1,TMBIM6,TNFRSF10B 6.09 0.02874 0.346367798982188 GO:0097300 programmed necrotic cell death biological_process 31 11 ARHGEF2,BIRC3,CD14,CFLAR,CYLD,DNM1L,FADD,RBCK1,SIRT2,TRPM7,YBX3 6.09 0.02874 0.346367798982188 GO:0009148 pyrimidine nucleoside triphosphate biosy... biological_process 20 8 DTYMK,NME4,NME5,NME6,NME7,NME9,TBPL1,TYMS 3.93 0.02893 0.346367798982188 GO:0032878 regulation of establishment or maintenan... biological_process 20 8 BCAS3,KANK1,KRIT1,LLGL2,PTK2B,RAP1B,RUFY3,SHTN1 3.93 0.02893 0.346367798982188 GO:0035418 protein localization to synapse biological_process 20 8 ANKS1B,ASIC2,BSN,DLG2,DLG3,LRRTM1,NRXN1,RELN 3.93 0.02893 0.346367798982188 GO:0043586 tongue development biological_process 20 8 EGFR,HDAC1,HDAC2,KRT13,PRDM16,SIX1,WNT10A,WNT10B 3.93 0.02893 0.346367798982188 GO:0046037 GMP metabolic process biological_process 20 8 CASK,DLG2,DLG3,GMPS,GUK1,HPRT1,IMPDH1,PDE6B 3.93 0.02893 0.346367798982188 GO:0051647 nucleus localization biological_process 20 8 CDC42,DCTN4,DOCK7,MYH10,PAFAH1B1,PCM1,PTK2,WDR43 3.93 0.02893 0.346367798982188 GO:0061462 protein localization to lysosome biological_process 20 8 CD81,GCC2,GNPTG,HGS,NAGPA,SNX16,SORL1,ZFYVE16 3.93 0.02893 0.346367798982188 GO:0070570 regulation of neuron projection regenera... biological_process 20 8 BRAF,CERS2,EPHA4,KLK8,NTRK3,PRRX1,PTEN,RGMA 3.93 0.02893 0.346367798982188 GO:0009124 nucleoside monophosphate biosynthetic pr... biological_process 92 26 ADA,ADK,AK2,AMPD3,APRT,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,CMPK1,ENTPD8,GART,GBAS,GMPS,HPRT1,IMPDH1,MT-ATP6,SLC25A13,SURF1,TGFB1,TK1,TYMS,UPRT 18.06 0.02895 0.346367798982188 GO:1902807 negative regulation of cell cycle G1/S p... biological_process 92 26 AURKA,BAX,BCL2,BRD7,CENPJ,CNOT2,CNOT7,CNOT8,E2F7,EZH2,FBXO7,FHL1,GIGYF2,JADE1,KANK2,MDM2,MDM4,MYO16,PCBP4,PLK3,PRMT1,PTEN,RFWD3,TP63,UBA52,ZNF385A 18.06 0.02895 0.346367798982188 GO:2000134 negative regulation of G1/S transition o... biological_process 92 26 AURKA,BAX,BCL2,BRD7,CENPJ,CNOT2,CNOT7,CNOT8,E2F7,EZH2,FBXO7,FHL1,GIGYF2,JADE1,KANK2,MDM2,MDM4,MYO16,PCBP4,PLK3,PRMT1,PTEN,RFWD3,TP63,UBA52,ZNF385A 18.06 0.02895 0.346367798982188 GO:0009127 purine nucleoside monophosphate biosynth... biological_process 71 21 ADA,ADK,AK2,AMPD3,APRT,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,GART,GBAS,GMPS,HPRT1,IMPDH1,MT-ATP6,SLC25A13,SURF1,TGFB1 13.94 0.02899 0.346367798982188 GO:0009168 purine ribonucleoside monophosphate bios... biological_process 71 21 ADA,ADK,AK2,AMPD3,APRT,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,GART,GBAS,GMPS,HPRT1,IMPDH1,MT-ATP6,SLC25A13,SURF1,TGFB1 13.94 0.02899 0.346367798982188 GO:0035304 regulation of protein dephosphorylation biological_process 144 38 ADORA1,ANKLE2,ARPP19,BAG4,CALM1,CAMSAP3,CD2BP2,CDCA2,CDK5RAP3,CEP192,CNST,CSRNP3,DLG2,DLG3,EIF2AK2,FARP1,HSP90B1,ITGA2,MASTL,MEF2C,MPHOSPH10,PDGFRB,PIN1,PPP1R12A,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP6R3,RGN,SEMA4D,SYTL2,TGFB1 28.27 0.02906 0.346762973316391 GO:0042274 ribosomal small subunit biogenesis biological_process 67 20 BMS1,CCDC59,DCAF13,HEATR1,KRR1,LSM6,LTV1,MPHOSPH10,MRPS11,NAT10,NGDN,NOM1,RCL1,RPS19,RPS5,RRP36,SNU13,UTP11,UTP14A,UTP4 13.15 0.02962 0.35238716507177 GO:0007399 nervous system development biological_process 2075 440 ABAT,ABI1,ABR,ACAT1,ACSBG1,ACTL6A,ADAM22,ADAM23,ADCYAP1,ADNP,ADORA1,AGTPBP1,AKT1,ALDH1A3,ALDH3A2,AMBRA1,ANK2,ANK3,ANKLE2,APBB1,APBB2,APLP1,ARF1,ARHGAP26,ARHGAP4,ARHGEF1,ARHGEF15,ARHGEF2,ARID1B,ARL6,ARMC4,ASIC2,ATAT1,ATIC,ATOH8,ATP2B1,ATP2B4,ATP6V0D1,ATRX,ATXN10,ATXN3,BAX,BBS2,BCHE,BCL2,BMPR1B,BOC,BOK,BPNT1,BPTF,BRAF,BRINP1,BRINP2,BSN,C16orf45,CACNA1A,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAPRIN1,CCDC14,CCDC66,CCDC88A,CD9,CDC42,CDH1,CDH23,CDK5RAP3,CDON,CELSR1,CELSR2,CEP290,CERS2,CHD7,CHL1,CHN1,CHODL,CHRD,CHRM2,CHRNA3,CLDN11,CLIP1,CLN8,CLU,CNTN1,COBL,COPS2,COX17,CPEB3,CPLX2,CPNE1,CRTAC1,CSF1R,CTNNA1,CTNND1,CTTNBP2,CUL4B,CUX1,CXCL12,CXCR2,CYFIP1,DAB2IP,DAG1,DAPK3,DCC,DCTN1,DDX56,DDX6,DGKG,DHFR,DICER1,DLG2,DLG3,DNM3,DOCK7,DOK4,DPCD,DPF1,DTX1,DUOXA1,ECT2,EGF,EGFR,EIF4E,EMX1,EN1,EPB41L3,EPHA4,EPHB2,ETV1,ETV5,ETV6,EVL,EZH2,FAM150A,FANCD2,FARP1,FARP2,FAS,FBXO7,FES,FEZ1,FEZ2,FGF12,FGF5,FGFR1,FKBP4,FKBP8,FMN1,FOXJ1,FOXN4,FRS2,FRY,FRYL,FUOM,FUT9,FZD6,GABRA5,GAK,GART,GBA2,GDA,GFRA2,GIGYF2,GJB1,GLI1,GMFB,GNGT1,GNPAT,GOLGA4,GORASP1,GPC1,GPM6A,GPRC5B,GPSM1,GRHL2,GSK3B,GSTP1,HAP1,HDAC1,HDAC2,HDAC6,HDAC9,HESX1,HEXB,HEYL,HMGCS1,HNRNPD,HOXB1,HPRT1,HYDIN,IFRD1,IL1RAPL2,IMMP2L,IMPACT,ITM2C,JAM3,KALRN,KANK1,KDM6A,KDM7A,KEL,KIF1BP,KLK8,KRAS,LBX1,LGI1,LHX6,LHX9,LIF,LIG4,LIMK1,LINGO3,LLGL2,LRCH4,LRP6,LRRTM1,LRRTM3,LSAMP,LTA,MACROD2,MAFK,MAN2A1,MAP1S,MAP2,MAP6,MAPK8IP3,MARK1,MBD3,MBD5,MBNL1,MCF2,MDM2,MEF2A,MEF2C,METRN,MFSD2A,MINK1,MKS1,MNAT1,MOB2,MSI1,MTCH1,MT-CO1,MTHFD1,MT-ND4,MTOR,MYH10,MYO16,MYOC,NAB1,NCK1,NCKIPSD,NCOA1,NCOA6,NDE1,NDRG2,NECTIN1,NEPRO,NF1,NFE2L2,NIF3L1,NIPBL,NKD1,NLGN3,NME5,NOM1,NPTX1,NRAS,NREP,NRP2,NRSN1,NRXN1,NTRK2,NTRK3,OLFM1,ONECUT2,OPA1,OPRM1,P2RX5,P2RY12,PAFAH1B1,PAK1,PAK2,PAK3,PAPD4,PAQR3,PAX2,PAX3,PAX7,PBX1,PCDH19,PCDHAC2,PCDHB12,PCM1,PGAP1,PICK1,PIGT,PIN1,PLA2G10,PLCB1,PLOD3,PLXNA1,PLXNB1,PLXNC1,PLXND1,POFUT1,PPP1CC,PRDM16,PRICKLE1,PRMT1,PRMT5,PROM1,PRRX1,PSMG1,PTBP2,PTEN,PTK2,PTK2B,PTPRA,PTPRK,PTS,PURA,RAB18,RACGAP1,RAP1A,RAP1GAP2,RAPGEF2,RAPH1,RBM45,RBPJ,RDH13,RELN,RGMA,RGS14,RNF6,ROBO1,ROBO3,ROGDI,RPS6KA6,RTN4,RTN4RL2,RUFY3,S1PR5,SCN3B,SDCCAG8,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPP1,SEPT2,SEPT4,SGK1,SH3GL1,SHANK2,SHTN1,SIM1,SIM2,SIRT2,SIX1,SIX3,SKIL,SLC11A2,SLC12A5,SLC1A3,SLC38A2,SLC7A11,SMAD4,SMAD9,SMARCA2,SMARCD1,SMARCE1,SNAPIN,SNTG2,SORL1,SOS1,SOX6,SPAG9,SPATA5,SPG7,SPINT2,SPTB,SPTBN1,SPTBN4,STAR,STK25,STMN4,STRC,STRN,SYPL2,SYT1,SZT2,TACC1,TACC2,TBX20,TBX3,TCF12,TCF7,TGFB1,TGFBR1,THOC2,THY1,TLR9,TMED2,TMEM57,TOP2B,TP63,TRA2B,TSHR,TTC21B,TWSG1,UBA6,UBE3A,UCHL5,UFL1,ULK2,UNK,USH2A,USP33,USP9X,UTP11,VEGFA,VPS13A,WEE1,WNT10A,WNT10B,WNT11,WRN,WWP1,XRCC5,YWHAQ,ZC3H12A,ZC4H2,ZEB1,ZNF148,ZNF280D 407.4 0.02962 0.35238716507177 GO:0086004 regulation of cardiac muscle cell contra... biological_process 35 12 ANK2,CACNA1C,CACNA2D1,FGF12,NEDD4L,NUP155,PDE4D,PKP2,RYR2,SCN3B,SRI,SUMO1 6.87 0.02999 0.35238716507177 GO:0000165 MAPK cascade biological_process 851 189 ADCYAP1,ADORA1,AKT1,ALOX15,ANKRD6,ARHGAP8,ASH1L,BIRC7,BRAF,C3orf33,C5AR2,CALM1,CAMK2A,CAMK2G,CCL25,CD44,CD74,CD81,CDC42,CDK12,CDK5RAP3,CDON,CHRNA7,CHUK,CRYAB,CSF1R,CUL1,CUL3,DAB2IP,DAG1,DNAJA1,DOK4,DUSP16,DUSP9,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM150A,FAM58A,FAS,FBXW11,FGF5,FGFR1,FRS2,GADD45G,GDF9,GFRA2,GSTP1,HACD3,HAVCR2,HGS,HIPK3,HTR2B,IGF1R,IL1B,IL2RA,IRAK1,IRAK4,ITGAV,ITGB1BP1,KRAS,LAMTOR1,LAMTOR3,LAT,LIF,LMO3,MADD,MAGED1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK3,MARVELD3,MEF2A,MEF2C,MINK1,MST1R,MYOC,NCOR1,NDRG2,NEK10,NF1,NLRP12,NOX1,NOX4,NRAS,NTRK2,NTRK3,OPRK1,OPRM1,PABPN1,PAFAH1B1,PAK1,PAK3,PAQR3,PBK,PDCD10,PDE5A,PDGFRB,PIK3CB,PIK3R5,PIN1,PLA2G5,PLCB1,PPP2R1A,PRKCZ,PRMT1,PRMT5,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRA,RAP1A,RAP1B,RAPGEF2,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP4,RBM4,RELT,RGS14,RGS3,ROS1,RPS6KA6,SASH1,SDCBP,SEMA7A,SH2D3C,SHC2,SMAD4,SORBS3,SORL1,SOS1,SPAG9,SPRY1,SPTB,SPTBN1,SPTBN4,STK25,TAB2,TAB3,TBC1D10C,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF19,TNFRSF25,TRAF4,TRIM5,UBA52,VEGFA,ZC3H12A 167.08 0.03017 0.35238716507177 GO:0051782 negative regulation of cell division biological_process 63 19 AURKB,BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,E2F7,GEN1,HORMAD1,LCMT1,LIF,MTBP,NME6,PSMG2,TEX14,TOM1L1,TTK,VPS4A,XRCC3,ZNF207 12.37 0.03019 0.35238716507177 GO:0050770 regulation of axonogenesis biological_process 171 44 ADNP,ARHGAP4,ARHGEF1,BRAF,CACNA1A,CERS2,CHN1,CXCL12,DCC,EPHA4,EPHB2,GOLGA4,GSK3B,IFRD1,KEL,KLK8,LIMK1,METRN,NTRK2,NTRK3,OLFM1,PAFAH1B1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PTEN,PTK2,RGMA,RNF6,ROBO1,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SKIL,STK25,THY1,ULK2,VEGFA 33.57 0.03029 0.35238716507177 GO:0000054 ribosomal subunit export from nucleus biological_process 10 5 ABCE1,EIF6,LTV1,SDAD1,XPO1 1.96 0.03039 0.35238716507177 GO:0006273 lagging strand elongation biological_process 10 5 DNA2,LIG3,LIG4,PARP2,POLA1 1.96 0.03039 0.35238716507177 GO:0006924 activation-induced cell death of T cells biological_process 10 5 AKT1,FADD,FAS,IL2RA,TSC22D3 1.96 0.03039 0.35238716507177 GO:0007016 cytoskeletal anchoring at plasma membran... biological_process 10 5 ANK3,DAG1,EPB41L3,SPTBN4,TLN1 1.96 0.03039 0.35238716507177 GO:0018202 peptidyl-histidine modification biological_process 10 5 DNAJC24,DPH1,DPH2,DPH3,DPH5 1.96 0.03039 0.35238716507177 GO:0033523 histone H2B ubiquitination biological_process 10 5 CTR9,LEO1,RNF8,UBE2E1,WAC 1.96 0.03039 0.35238716507177 GO:0033750 ribosome localization biological_process 10 5 ABCE1,EIF6,LTV1,SDAD1,XPO1 1.96 0.03039 0.35238716507177 GO:0033753 establishment of ribosome localization biological_process 10 5 ABCE1,EIF6,LTV1,SDAD1,XPO1 1.96 0.03039 0.35238716507177 GO:0035459 cargo loading into vesicle biological_process 10 5 KIF13A,MIA3,RAB1A,SEC24B,TMED2 1.96 0.03039 0.35238716507177 GO:0035999 tetrahydrofolate interconversion biological_process 10 5 FTCD,MTHFD1,MTHFD2L,SHMT2,TYMS 1.96 0.03039 0.35238716507177 GO:0048149 behavioral response to ethanol biological_process 10 5 CHRNA7,CRHBP,HDAC2,OPRM1,UNC79 1.96 0.03039 0.35238716507177 GO:0051085 chaperone mediated protein folding requi... biological_process 10 5 CD74,ERO1A,HSPA8,HSPD1,HSPH1 1.96 0.03039 0.35238716507177 GO:0051231 spindle elongation biological_process 10 5 AURKB,KIF23,PPP2R1A,PRC1,RACGAP1 1.96 0.03039 0.35238716507177 GO:0051988 regulation of attachment of spindle micr... biological_process 10 5 CDC42,ECT2,RACGAP1,SIRT2,SPAG5 1.96 0.03039 0.35238716507177 GO:0071372 cellular response to follicle-stimulatin... biological_process 10 5 GCLC,GCLM,HMGCS1,POR,STAR 1.96 0.03039 0.35238716507177 GO:2000121 regulation of removal of superoxide radi... biological_process 10 5 DHFR,FBLN5,NFE2L2,RGN,SZT2 1.96 0.03039 0.35238716507177 GO:0002768 immune response-regulating cell surface ... biological_process 363 86 ABI1,ACTG1,ACTR2,ADA,ARPC1A,ARPC1B,BCAR1,BCL2,BLK,BTK,C5AR2,CACNB3,CALM1,CD247,CD3G,CD79B,CDC42,CHUK,CLEC4E,CR1,CUL1,CYFIP1,DENND1B,ELF1,FBXW11,FCGR1B,FYB,GCSAM,HLA-DPB1,KRAS,LAT,LIMK1,MALT1,MAP2K4,MAP2K7,MAPK8,MEF2C,MYO10,MYO1G,NCK1,NCKIPSD,NFATC1,NRAS,PAK1,PAK2,PAK3,PAWR,PDE4D,PIGR,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTPN2,PTPN6,RBCK1,SOS1,TAB2,TAB3,THY1,UBA52,UBE2V1,VAV1,ZAP70 71.27 0.03069 0.35238716507177 GO:1903115 regulation of actin filament-based movem... biological_process 39 13 ANK2,CACNA1C,CACNA2D1,FGF12,NEDD4L,NUP155,PDE4D,PKP2,RYR2,SCN3B,SRI,SUMO1,TNNT2 7.66 0.03078 0.35238716507177 GO:0032392 DNA geometric change biological_process 84 24 ATRX,BRIP1,CHD1,CHD2,CHD3,CUL4B,DDB1,DDX1,DNA2,GTF2H2,GTF2H3,GTF2H5,HELB,INO80,MCM2,POT1,PURA,RAD54B,RECQL5,TOP2B,UBA52,WRN,XRCC5,ZRANB3 16.49 0.03083 0.35238716507177 GO:0060249 anatomical structure homeostasis biological_process 326 78 ACACA,ACTG1,AIPL1,AKR1B1,ANKRD11,ATR,ATRX,AURKB,BAX,BBS1,BBS2,BCL2,CCT3,CCT7,CD7,CDH23,CDHR1,CIB2,CSF1R,CTC1,CXADR,DNA2,DRAM2,EGFR,GIGYF2,HDAC8,HNRNPC,HNRNPU,IQCB1,KMT2A,KRAS,LAMP2,LTF,MAP2K7,MAPKAPK5,MKS1,MUC4,NAT10,NEK7,NF1,NOP10,NOX4,NSMCE2,PIGR,PNKP,POC1B,POLA1,POLA2,POLD3,POLD4,POT1,PRIM1,PROM1,PTH1R,PTK2B,RAC2,RAD51C,RFC2,RFC4,RPA3,SERPINA3,SMC6,SMG1,SMG6,STRAP,TCP1,TF,TFIP11,TFRC,TLR9,TNKS,USH1C,USH2A,VEGFA,VPS54,WRN,XRCC3,XRCC5 64.01 0.03086 0.35238716507177 GO:0050999 regulation of nitric-oxide synthase acti... biological_process 43 14 AKT1,ATP2B4,CALM1,DHFR,EGFR,FCER2,GLA,HTR2B,IL1B,KRAS,LYPLA1,NOS3,PTK2B,PTS 8.44 0.03122 0.35238716507177 GO:0001821 histamine secretion biological_process 7 4 ADA,ADCYAP1,BTK,SNAP23 1.37 0.03126 0.35238716507177 GO:0002091 negative regulation of receptor internal... biological_process 7 4 ANXA2,ATXN2,LRRTM1,SDCBP 1.37 0.03126 0.35238716507177 GO:0006729 tetrahydrobiopterin biosynthetic process biological_process 7 4 DHFR,PCBD1,PTS,QDPR 1.37 0.03126 0.35238716507177 GO:0030913 paranodal junction assembly biological_process 7 4 ANK2,CD9,EPB41L3,GNPAT 1.37 0.03126 0.35238716507177 GO:0032466 negative regulation of cytokinesis biological_process 7 4 AURKB,E2F7,TEX14,VPS4A 1.37 0.03126 0.35238716507177 GO:0035280 miRNA loading onto RISC involved in gene... biological_process 7 4 AGO1,AGO2,DICER1,TARBP2 1.37 0.03126 0.35238716507177 GO:0036302 atrioventricular canal development biological_process 7 4 CHD7,FOXN4,RBPJ,SMAD4 1.37 0.03126 0.35238716507177 GO:0045617 negative regulation of keratinocyte diff... biological_process 7 4 GRHL2,HOXA7,MSX2,TP63 1.37 0.03126 0.35238716507177 GO:0046069 cGMP catabolic process biological_process 7 4 PDE1B,PDE2A,PDE5A,PDE9A 1.37 0.03126 0.35238716507177 GO:0046146 tetrahydrobiopterin metabolic process biological_process 7 4 DHFR,PCBD1,PTS,QDPR 1.37 0.03126 0.35238716507177 GO:0051683 establishment of Golgi localization biological_process 7 4 CDC42,PDCD10,STK25,YWHAZ 1.37 0.03126 0.35238716507177 GO:0090091 positive regulation of extracellular mat... biological_process 7 4 CARMIL2,CLASP1,CLASP2,DDR2 1.37 0.03126 0.35238716507177 GO:1901894 regulation of calcium-transporting ATPas... biological_process 7 4 RGN,RYR2,SUMO1,TLR9 1.37 0.03126 0.35238716507177 GO:2000427 positive regulation of apoptotic cell cl... biological_process 7 4 C2,C4A,C4B,MFGE8 1.37 0.03126 0.35238716507177 GO:2000766 negative regulation of cytoplasmic trans... biological_process 7 4 CPEB1,CPEB3,HAP1,UNK 1.37 0.03126 0.35238716507177 GO:2001032 regulation of double-strand break repair... biological_process 7 4 HMGA2,RIF1,TFIP11,WHSC1 1.37 0.03126 0.35238716507177 GO:0048588 developmental cell growth biological_process 158 41 ADNP,ARHGAP4,COBL,CXCL12,CYFIP1,DCC,DDX39B,GDF9,GOLGA4,GSK3B,HDAC6,IFRD1,KMT2D,LIMK1,MAP2K4,MTOR,NLGN3,NRP2,NTRK3,OLFM1,PAFAH1B1,PIN1,PLXNA1,PLXNB1,PLXNC1,PLXND1,RAPH1,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SIRT6,SORBS2,ULK2,USP9X,VEGFA 31.02 0.03128 0.35238716507177 GO:0071478 cellular response to radiation biological_process 158 41 ATF4,ATR,AURKB,BAX,CALM1,CNGA1,CRYAB,CUL4B,DDB1,ECT2,EEF1D,FIGNL1,FNTA,GNGT1,GTF2H5,HMGA2,HUS1,HYAL1,HYAL3,IMPACT,INO80,MDM2,METAP2,MME,N4BP1,NIPBL,NMT1,NOX4,NUCKS1,PBK,PDE6B,PTPRK,RAD51AP1,RHBDD1,RRH,TANK,TGFB1,TLK2,TP63,WRN,XRCC5 31.02 0.03128 0.35238716507177 GO:0006513 protein monoubiquitination biological_process 51 16 CTR9,CUL1,CUL3,CUL4B,DDB1,FANCL,LEO1,MGRN1,NEDD4L,RAD18,RNF2,UBE2B,UBE2E1,UBE2T,UBE2W,WAC 10.01 0.03130 0.35238716507177 GO:0030490 maturation of SSU-rRNA biological_process 47 15 BMS1,CCDC59,DCAF13,HEATR1,KRR1,LSM6,MPHOSPH10,MRPS11,NGDN,RCL1,RPS19,RRP36,SNU13,UTP14A,UTP4 9.23 0.03137 0.35238716507177 GO:0031110 regulation of microtubule polymerization... biological_process 47 15 ANKRD53,ARHGEF2,C16orf45,CLASP1,CLASP2,CLIP1,DCTN1,EML2,FES,FKBP4,HDAC6,MAP6D1,MID1IP1,SLAIN2,STMN4 9.23 0.03137 0.35238716507177 GO:1903313 positive regulation of mRNA metabolic pr... biological_process 47 15 AGO2,CNOT7,CNOT8,CPEB3,HSPA8,LEO1,NCBP2,PABPC1,PNPT1,POLR2G,PRR5L,RBMX,THRAP3,TRA2B,ZC3H12A 9.23 0.03137 0.35238716507177 GO:0019058 viral life cycle biological_process 410 96 AAAS,APOBEC3F,BCL2,CCNT1,CCNT2,CD46,CD81,CDHR3,CHD1,CHMP3,CHMP5,CHMP6,CLEC5A,CR1,CTBP1,CXADR,DAG1,DDB1,DDX39B,DDX6,EIF2AK2,FAM111A,FKBP6,GSN,GTF2B,HACD3,HDAC1,HMGA2,ITGA2,ITGAV,ITGB6,LTF,NDC1,NECTIN1,NEDD4L,NUCKS1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,PABPC1,PARP10,PCSK5,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PPIE,RAB1A,RAE1,RANBP2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SEH1L,SP1,SRPK2,SUPT4H1,TARBP2,TFRC,THOC1,THOC2,THOC7,TRIM38,TRIM5,UBA52,USP6NL,UVRAG,VPS4A,VTA1,WWP1,XPO1 80.5 0.03141 0.352414946236559 GO:0032270 positive regulation of cellular protein ... biological_process 1337 289 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ANKLE2,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARIH1,ARL2BP,ATP2B4,AURKA,BAG4,BAX,BCL2,BIRC3,BIRC7,BOK,BOLL,BRAF,BRCA1,BRD7,BUB1B,C1QBP,C5AR2,CACUL1,CALM1,CASP8,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CD44,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK5RAP3,CDON,CHFR,CHRNA3,CHRNA7,CHTOP,CLU,CNTN1,COL4A3,CPEB3,CR1,CSF1R,CTBP1,CTR9,CUL1,CUL3,DAB2IP,DAPK1,DCUN1D4,DDR2,DDX39B,DIABLO,DOCK7,DUSP9,ECT2,EGF,EGFR,EIF2AK2,EIF6,ENPP2,EPHA4,EZH2,FADD,FAM150A,FAM58A,FANCI,FAS,FBXO22,FBXW11,FGFR1,FNTA,FRS2,FZR1,GADD45G,GCLC,GDF9,GPRC5B,GSK3B,GSN,HACD3,HAVCR2,HDAC1,HDAC2,HNRNPD,HSPD1,HSPH1,HTR2B,IGF1R,IL15,IL1B,IMPACT,IRAK1,ITGA2,ITGB1BP1,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LIF,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MDM2,MEF2C,MINK1,MOB2,MST1R,MTCH1,MTF2,MTOR,MYB,NEK10,NIPBL,NLRP12,NOX1,NOX4,NRDC,NSMCE2,NSUN4,NTRK2,NTRK3,NUB1,OGT,OPRK1,OPRM1,OSBPL8,PABPC1,PAK1,PAK2,PAK3,PAX7,PAXBP1,PCOLCE2,PDCD10,PDCD2,PDCD5,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PLA2G10,PLA2G5,PLCB1,PLK3,POLDIP3,POLR2G,PPP1R12A,PPP1R7,PPP2R3C,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTTG1IP,RALB,RAP1A,RAP1B,RAPGEF2,RBPMS,RCHY1,RELN,RELT,RGN,RHBDD1,RNF138,RNF14,RNF166,ROBO1,RPS6KB1,RPS6KB2,RXRA,SASH1,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SERP1,SHC2,SIRT2,SMAD4,SMYD3,SNX9,SORBS3,SPAG9,SPDYA,SPRTN,STAP2,STK25,SUMO1,SUMO2,TAB2,TAB3,TANK,TARBP2,TBK1,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNK2,TOM1L1,TRADD,TRAF4,TRIM5,TTK,UBA52,UBE2E1,UBE3A,VEGFA,WNT11,XIAP,YBX3,ZC3H12A,ZP4 262.51 0.03195 0.357731060786651 GO:0044106 cellular amine metabolic process biological_process 203 51 ABAT,ABHD3,ALDH7A1,AMD1,ATP2B4,AZIN2,BCHE,CLN3,DBI,DUOXA1,ENPP2,FABP5,HDC,HPRT1,IDO1,LPCAT3,LPCAT4,LPIN1,OAZ1,OAZ2,PAFAH1B1,PCYT1A,PDE1B,PLA2G10,PLA2G4B,PLA2G4C,PLA2G5,PLBD1,PON1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SGMS1,SLC44A4 39.86 0.03196 0.357731060786651 GO:0001731 formation of translation preinitiation c... biological_process 24 9 EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4B,EIF4H,MCTS1 4.71 0.03234 0.358989290780142 GO:0007099 centriole replication biological_process 24 9 BRCA1,CENPJ,CEP135,CEP63,KIAA0753,MDM1,OFD1,PLK4,SASS6 4.71 0.03234 0.358989290780142 GO:0031111 negative regulation of microtubule polym... biological_process 24 9 ARHGEF2,C16orf45,CLASP1,CLASP2,EML2,FKBP4,HDAC6,MAP6D1,MID1IP1 4.71 0.03234 0.358989290780142 GO:0032770 positive regulation of monooxygenase act... biological_process 24 9 AKT1,CALM1,DHFR,FCER2,HTR2B,IL1B,KRAS,POR,PTK2B 4.71 0.03234 0.358989290780142 GO:0040001 establishment of mitotic spindle localiz... biological_process 24 9 ARHGEF2,CENPA,CLASP1,NDE1,NUSAP1,PAFAH1B1,SPDL1,SPRY1,WDR43 4.71 0.03234 0.358989290780142 GO:0060260 regulation of transcription initiation f... biological_process 24 9 ATF7IP,CAND1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,WNT10B,ZNF451 4.71 0.03234 0.358989290780142 GO:0098534 centriole assembly biological_process 24 9 BRCA1,CENPJ,CEP135,CEP63,KIAA0753,MDM1,OFD1,PLK4,SASS6 4.71 0.03234 0.358989290780142 GO:0009653 anatomical structure morphogenesis biological_process 2578 541 ABI1,ABLIM3,ABR,ACTG1,ACTN1,ACTR2,ADA,ADIPOR1,ADIPOR2,ADNP,AFF3,AGFG1,AGTPBP1,AKIP1,ALDH1A3,ALOX15,ALPL,ANGPT2,ANGPTL3,ANK2,ANK3,ANKRD11,ANKRD6,ANTXR1,ANXA2,ANXA7,APBB1,APBB2,APLP1,ARFRP1,ARHGAP4,ARHGEF1,ARHGEF15,ARHGEF2,ARL6,ARMC4,ATF2,ATIC,ATMIN,ATOH8,ATP5B,ATP6V0D1,ATRX,ATXN10,AURKA,BAX,BBS1,BBS2,BCAS3,BCL2,BICD1,BMPR1B,BOC,BRAF,BRCA1,BRWD3,BTBD7,C16orf45,C1QBP,CACNA1A,CACNA1C,CACNA1H,CALB1,CAMK2A,CAPRIN1,CARMIL2,CCDC114,CCDC66,CD44,CD9,CDC42,CDC42EP3,CDH13,CDON,CELSR1,CELSR2,CEP164,CEP290,CEP89,CERS2,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,CFLAR,CHAD,CHD7,CHL1,CHN1,CHRD,CHRNA3,CHRNA7,CHUK,CLASP1,CLASP2,CLTC,CLU,CNOT2,COBL,COL4A3,COL6A1,CPQ,CRTAC1,CRYAB,CSF1R,CSF3R,CSNK1G1,CTNNA1,CTR9,CUL1,CUL3,CUX1,CXCL12,CXCL17,CXCR2,CYBB,CYFIP1,DAAM1,DAB2IP,DAG1,DAPK3,DCC,DDR1,DDR2,DHFR,DICER1,DKKL1,DLD,DLG3,DMRT2,DNAI1,DNAI2,DNM1L,DNM3,DOCK7,DRC1,E2F5,E2F7,ECT2,EGF,EGFL7,EGFR,EHD2,ELF3,ELN,EMX1,EN1,ENPP2,EPB41L3,EPHA4,EPHB2,ESR1,ETV1,ETV5,ETV7,EVL,EXOC4,EYA3,EYA4,EZH2,FAM161A,FANCD2,FARP1,FAT1,FBF1,FBLIM1,FBN1,FER1L5,FES,FEZ1,FEZ2,FGD3,FGD4,FGD6,FGFR1,FHL1,FHOD3,FMN1,FMNL2,FNBP1L,FOXJ1,FOXN3,FOXN4,FRAS1,FRMD6,FRS2,FRY,FRYL,FZD6,GALNT11,GCNT3,GLI1,GNA12,GNGT1,GNPAT,GOLGA4,GORASP1,GPC1,GPC3,GPM6A,GRHL2,GSK3B,GSN,GSTP1,GTF2I,GZF1,HDAC1,HDAC2,HDAC6,HDAC7,HDAC9,HESX1,HEXB,HEYL,HMGA2,HMGN1,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HPRT1,HSPB11,HTR2B,HYAL1,IFRD1,IGF2BP3,IGF2R,IL1B,IL4R,IQCB1,IQCG,IRX4,ITGA2,ITGA6,ITGA7,ITGAV,ITGB1BP1,ITGB4,JAM3,JMJD6,KALRN,KANK1,KDM6A,KEL,KLHL3,KLK8,KRAS,KRIT1,KRT13,KRT16,LARP4,LBX1,LCP1,LEO1,LFNG,LGI1,LGR4,LGR5,LHX9,LIF,LIMD1,LIMK1,LIMS2,LINGO3,LPIN1,LRIG3,LRP6,LTF,MAGED1,MAN2A1,MAP1S,MAP2,MAP2K5,MAP6,MAPK8IP3,MARCH5,MBNL1,MCAM,MDM2,MEF2A,MEF2C,MEGF11,METRN,MFF,MFGE8,MINK1,MKI67,MKLN1,MKS1,MMP19,MMRN2,MSX2,MTDH,MTHFD1,MTOR,MYF6,MYH10,MYH9,MYLK,MYO10,MYOC,MYOZ3,NAB1,NCOA1,NECTIN1,NF1,NFE2L1,NFE2L2,NIPBL,NKD1,NLGN3,NME5,NOS3,NOX1,NOX4,NOX5,NPRL3,NPTX1,NRAS,NREP,NRP2,NRXN1,NTRK2,NTRK3,OCRL,OFD1,OLFM1,OMA1,ONECUT2,OPA1,OTULIN,PAFAH1B1,PAK1,PAK3,PALLD,PAX2,PAX3,PAX4,PAX7,PBX1,PCM1,PCSK5,PDCD10,PDCL3,PDGFRB,PEAK1,PFKFB1,PHIP,PHLDB1,PIK3CA,PIK3CB,PKDCC,PKP2,PLA2G10,PLCD3,PLOD3,PLXNA1,PLXNB1,PLXNC1,PLXND1,PNPT1,POC1B,POFUT1,POGLUT1,POLB,POR,PRICKLE1,PRMT5,PROM1,PRPF40A,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTPN6,PTPRA,RAB1A,RADIL,RAP1A,RAPGEF2,RAPH1,RBPJ,RDH10,RDH13,RELN,RFX2,RGMA,RGN,RHOC,RNF2,RNF6,RNH1,ROBO1,ROBO3,ROGDI,RP2,RPGR,RPL32,RPL7L1,RPS6KA1,RSPH9,RTN4,RTN4RL2,RUFY3,RXRA,RYR2,SART3,SASH1,SCFD1,SDCBP,SDCCAG8,SDHAF2,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT2,SEPT7,SERP1,SF3B6,SFTPB,SGK1,SGPL1,SHTN1,SIDT2,SIRT6,SIX1,SIX3,SKIL,SLC11A2,SLC1A3,SLC34A1,SMAD2,SMAD4,SNX2,SOS1,SOX6,SP3,SP9,SPAG16,SPINT2,SPRY1,SPTB,SPTBN1,SPTBN4,SRPK2,SRSF5,SS18,SSBP1,SSX2IP,STAT6,STK25,STRAP,STRC,SUPT20H,SZT2,TAPT1,TBPL1,TBX20,TBX3,TCF7,TGFB1,TGFB1I1,TGFBR1,THSD7A,THY1,TIPARP,TLR9,TMED2,TMEFF2,TMEM237,TMEM67,TNFSF12 506.16 0.03251 0.360450306965761 GO:0002253 activation of immune response biological_process 519 119 ABI1,ACOD1,ACTG1,ACTR2,ADA,ARPC1A,ARPC1B,BCAR1,BCL2,BIRC3,BLK,BPIFB1,BTK,C1QBP,C1RL,C1S,C2,C4A,C4B,C5AR2,CACNB3,CASP8,CD14,CD247,CD3G,CD46,CD79B,CDC42,CHUK,CLEC4E,CLU,COLEC11,CR1,CUL1,CYFIP1,CYLD,DAB2IP,DENND1B,DMBT1,ELF1,ESR1,FADD,FBXW11,FYB,GCSAM,HAVCR2,HLA-DPB1,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LAT,LGR4,LIMK1,LTF,MALT1,MEF2C,MYO10,MYO1G,NCK1,NCKIPSD,NRAS,OTULIN,PAK1,PAK2,PAK3,PAWR,PDE4D,PELI1,PGLYRP2,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTPN2,PTPN6,PUM2,RBCK1,SEC14L1,SUSD4,TAB2,TAB3,TANK,TBK1,THY1,TLR1,TLR7,TLR9,TRIM5,UBA52,UBE2V1,UNC93B1,VAV1,XIAP,ZAP70 101.9 0.03290 0.364344221698113 GO:0006470 protein dephosphorylation biological_process 327 78 ACP1,ADORA1,ANKLE2,ARPP19,BAG4,BCL2,CALM1,CAMK2G,CAMSAP3,CD2BP2,CDC14B,CDCA2,CDK5RAP3,CDKN3,CEP192,CNST,CSRNP3,CTDNEP1,CTDSPL2,CTTNBP2NL,DLG2,DLG3,DUSP13,DUSP16,DUSP9,EIF2AK2,EYA3,EYA4,FARP1,FBXW11,HSP90B1,ITGA2,MASTL,MEF2C,MPHOSPH10,MTMR1,MTMR7,NCK1,PDGFRB,PIN1,PPM1B,PPM1M,PPP1CB,PPP1CC,PPP1R12A,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP4R3B,PPP6R3,PPTC7,PTEN,PTP4A2,PTPN13,PTPN2,PTPN20,PTPN6,PTPRA,PTPRK,PTPRN,PTPRT,RGN,SBF1,SDHAF2,SEMA4D,SYTL2,TGFB1,TIMM50,TNS2,UBLCP1 64.2 0.03294 0.364357526501767 GO:0006367 transcription initiation from RNA polyme... biological_process 172 44 ATF7IP,CAND1,CCNC,CDK7,ESR1,ESRRB,ESRRG,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,KAT2B,MED13,MED14,MED16,MED23,MED24,MED30,MED31,MNAT1,NCOA6,NR2C1,NR3C1,NR3C2,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RBPJ,RORC,RXRA,TAF2,TEAD1,THRAP3,WNT10B,WWTR1,ZNF451 33.77 0.03319 0.366690929411765 GO:0006400 tRNA modification biological_process 72 21 ADAT2,CDKAL1,METTL1,MTO1,NAT10,PDCL3,QTRT1,RPUSD1,RPUSD4,SSB,TARBP1,THUMPD1,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,TRUB1,TYW5,UBA5 14.14 0.03359 0.370674136310223 GO:0035303 regulation of dephosphorylation biological_process 150 39 ADORA1,ANKLE2,ARPP19,BAG4,CALM1,CAMSAP3,CD2BP2,CDCA2,CDK5RAP3,CEP192,CNST,CSRNP3,DLG2,DLG3,EIF2AK2,FARP1,HSP90B1,ITGA2,MASTL,MEF2C,MPHOSPH10,PDGFRB,PIN1,PPP1R12A,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP6R3,RGN,SEMA4D,SMG6,SYTL2,TGFB1 29.45 0.03401 0.374220430232558 GO:2001020 regulation of response to DNA damage sti... biological_process 128 34 APBB1,ATR,BCLAF1,BRCA1,CD44,CD74,DDX39B,EGFR,EYA3,EYA4,FIGNL1,HELB,HMGA2,MDM2,NSMCE1,NSMCE4A,PARPBP,PPP4C,PTTG1IP,RAD51AP1,RAD52,RFWD3,RIF1,RNF8,SENP2,SIRT6,SLF1,SMYD2,TFIP11,THOC1,TIGAR,TRIP12,UBE2V1,WHSC1 25.13 0.03419 0.374220430232558 GO:0000076 DNA replication checkpoint biological_process 17 7 CDC6,DNA2,HUS1,NAE1,RAD17,SLF1,TOPBP1 3.34 0.03427 0.374220430232558 GO:0031442 positive regulation of mRNA 3-end proce... biological_process 17 7 AGO2,CNOT7,CPEB3,LEO1,NCBP2,PABPC1,POLR2G 3.34 0.03427 0.374220430232558 GO:0032647 regulation of interferon-alpha productio... biological_process 17 7 HAVCR2,HSPD1,IRF5,NMI,TBK1,TLR7,TLR9 3.34 0.03427 0.374220430232558 GO:0046655 folic acid metabolic process biological_process 17 7 ALDH1L1,DHFR,MTHFD1,MTHFD2L,MTRR,SHMT2,SLC25A32 3.34 0.03427 0.374220430232558 GO:0060261 positive regulation of transcription ini... biological_process 17 7 CAND1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,WNT10B 3.34 0.03427 0.374220430232558 GO:2000114 regulation of establishment of cell pola... biological_process 17 7 BCAS3,KANK1,KRIT1,PTK2B,RAP1B,RUFY3,SHTN1 3.34 0.03427 0.374220430232558 GO:2001269 positive regulation of cysteine-type end... biological_process 17 7 BAX,CASP8,FADD,FAS,GSN,TNFRSF10B,TRADD 3.34 0.03427 0.374220430232558 GO:1900542 regulation of purine nucleotide metaboli... biological_process 888 196 ABR,ACAP1,ACAP2,ADCY4,ADCYAP1,ADGRD1,ADNP,ADPRHL1,AGFG1,AHSA2,AIPL1,AKAP12,AMPH,APLP1,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ATP1B1,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,EIF6,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GABBR1,GCGR,GDI2,GFRA2,GIPR,GMIP,GRM7,GRM8,GSK3B,HACD3,HNRNPU,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MCF2,MCF2L,METTL21A,MTOR,NCK1,NCOR1,NF1,NOS3,NPRL3,NTRK2,OCRL,OGT,OPRM1,P2RY12,PAFAH1B1,PDE2A,PDE4D,PDE5A,PDE6D,PDGFRB,PDZD3,PFN2,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTK2B,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT6,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TBL1XR1,THY1,TIGAR,TLR9,TMED2,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,TSHR,USP6NL,VAV1,VEGFA,WNT11 174.35 0.03441 0.375312787456446 GO:0006304 DNA modification biological_process 102 28 ALKBH2,APOBEC3F,ATF7IP,ATRX,BAZ2A,BRCA1,EHMT1,EHMT2,EZH2,FKBP6,GATAD2A,GATAD2B,GRHL2,GSK3B,HELLS,KDM1B,KMT2A,KMT2E,MBD3,MTRR,MUTYH,PICK1,PIK3CA,PIWIL4,PRMT5,RLF,TDRD5,USP7 20.03 0.03460 0.376617098265896 GO:0045088 regulation of innate immune response biological_process 351 83 ACOD1,AP1G1,BIRC3,BPIFB1,BTK,C1QBP,CASP8,CD14,CHUK,CLEC4E,CR1,CUL1,CYLD,DAB2IP,DMBT1,ESR1,FADD,FBXW11,GBP5,HAVCR2,HSP90B1,HSPD1,IRAK1,IRAK4,KRAS,LGR4,LTF,MALT1,NCR1,NLRC5,NMI,NRAS,OTULIN,PAK1,PAK2,PAK3,PELI1,PGLYRP2,PIAS1,PIK3C3,POLR3C,POLR3F,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTPN2,PTPN6,PUM2,RPS19,SEC14L1,SERPINB4,SUMO1,TAB2,TAB3,TANK,TBK1,TLR1,TLR7,TLR9,TRIM5,TYK2,UBA52,UBE2V1,UNC93B1,VAV1,XIAP 68.92 0.03463 0.376617098265896 GO:0051973 positive regulation of telomerase activi... biological_process 28 10 AURKB,GRHL2,MAP2K7,MAPKAPK5,NEK7,NVL,PNKP,POT1,TCP1,TNKS 5.5 0.03469 0.376617098265896 GO:0070897 DNA-templated transcriptional preinitiat... biological_process 28 10 ATF7IP,CAND1,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,TAF1B,TAF2,WNT10B 5.5 0.03469 0.376617098265896 GO:0060828 regulation of canonical Wnt signaling pa... biological_process 236 58 AMER1,AMER3,ANKRD10,ANKRD6,CTDNEP1,CTNND1,CUL3,CYLD,DAB2IP,DAPK3,FZD6,GLI1,GPC3,GPRC5B,GSK3B,HDAC1,IGFBP2,JADE1,LGR4,LGR5,LIMD1,LRP6,LZTS2,MKS1,NKD1,PIN1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RBPJ,RNF220,SCYL2,SDHAF2,TNKS,UBA52,USP34,WNT10B,WNT11,WWTR1,XIAP 46.34 0.03527 0.380978042105263 GO:0009411 response to UV biological_process 124 33 AKT1,ATF4,ATR,AURKB,BAX,BCL2,CUL4B,DDB1,EGFR,GTF2H2,HMGN1,HUS1,HYAL1,HYAL3,IMPACT,INO80,MAP2K7,MAPK8,MDM2,MME,N4BP1,PBK,PTPRK,RAD18,REV1,RHBDD1,SPRTN,TP63,TROVE2,UBE2B,UVSSA,WRN,ZRANB3 24.35 0.03560 0.380978042105263 GO:0010921 regulation of phosphatase activity biological_process 124 33 ANKLE2,ARPP19,BAG4,CALM1,CAMSAP3,CD2BP2,CDK5RAP3,CEP192,CNST,CSRNP3,DLG2,DLG3,EIF2AK2,FARP1,HSP90B1,ITGA2,MASTL,MEF2C,MPHOSPH10,PDGFRB,PPP1R12A,PPP1R2P3,PPP1R42,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP6R3,RGN,SEMA4D,SYTL2 24.35 0.03560 0.380978042105263 GO:0031032 actomyosin structure organization biological_process 155 40 ACTG1,ARHGAP6,ARHGEF15,BAG4,BRAF,CFLAR,CLASP1,CLASP2,CUL3,EPB41L3,EVL,FHOD3,FRMD3,FRMD6,ITGB1BP1,KIF23,LIMCH1,LIMK1,MEF2A,MEF2C,MTOR,MYH10,MYH9,MYO18A,MYOC,MYOZ3,NOX4,PAK1,PDCD10,PDGFRB,PFN2,PTK2B,RACGAP1,SORBS3,SYNPO,TGFBR1,TMEFF2,TRPM7,WNT11,ZYX 30.43 0.03587 0.380978042105263 GO:0002260 lymphocyte homeostasis biological_process 60 18 ADA,AKT1,BAX,BCL2,CCNB2,CD74,FADD,FAS,IL2RA,LAT,MEF2C,PPP2R3C,SKIL,SOS1,TGFB1,TNFRSF13B,TSC22D3,ZC3H8 11.78 0.03603 0.380978042105263 GO:0051336 regulation of hydrolase activity biological_process 1297 280 ABCE1,ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AHSA2,AIP,AKT1,AMPH,ANGPTL3,ANKLE2,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ARL1,ARPP19,ATP1B1,BAG4,BAX,BCAS3,BICD1,BIRC3,BIRC6,BIRC7,BNIP2,BOK,C4A,C4B,CALM1,CAMK2A,CAMK2G,CAMSAP3,CARD16,CASP8,CCL25,CCZ1,CD2BP2,CD44,CDC42EP3,CDK5RAP3,CEP192,CFAP100,CFAP73,CHN1,CHTOP,CNST,COL4A3,CR1,CRYAB,CSNK2A1,CSRNP3,CSTL1,CYTH4,DAB2IP,DAPK1,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DIABLO,DLG2,DLG3,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,EIF2AK2,ELMOD3,EPHA4,EPS8L1,ESR1,EZH2,FADD,FAM13B,FARP1,FARP2,FAS,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FNTA,FRS2,GCGR,GDI2,GFRA2,GMIP,GPC3,GPIHBP1,GSK3B,GSN,HACD3,HNRNPU,HSP90B1,HSPD1,HTR2B,IL2RA,INPP5B,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MAP2K5,MAPK8,MASTL,MCF2,MCF2L,MDM2,MEF2C,METTL21A,MPHOSPH10,MTCH1,MTOR,NCK1,NDE1,NF1,NLRP12,NOS3,NPRL3,NRDC,NTRK2,OCRL,OVOS2,P2RY12,PAFAH1B1,PAK2,PAX2,PCOLCE2,PDCD2,PDCD5,PDE6D,PDGFRB,PFN2,PIK3R2,PIN1,PKP4,PLA2G5,PLCB1,PLCB2,PLEKHG2,PLEKHG6,PLXNB1,POR,POT1,PPP1R12A,PPP1R2P3,PPP1R42,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP6R3,PREB,PRKCZ,PSD3,PSD4,PSMA3,PSMB9,PSME3,PSME4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOC,RIC1,RIC8B,ROBO1,RP2,RPGR,RPS6KA1,RUNDC1,RYR2,SBF1,SEMA4D,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPINT2,SPOCK3,SPRY1,SPTB,SPTBN1,SPTBN4,SSBP1,ST5,SUMO1,SYTL2,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TFPI,THY1,TLR9,TMBIM6,TMED2,TNFRSF10B,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TP63,TRADD,TRIO,TRIP10,UCHL5,USP6NL,VAV1,VEGFA,VIL1,WDR43,WFDC2,WNT11,WRN,XIAP 254.65 0.03622 0.380978042105263 GO:0006623 protein targeting to vacuole biological_process 32 11 GCC2,GNPTG,HGS,NAGPA,SNX16,SORL1,TRAPPC8,VPS13A,VPS13C,VPS36,ZFYVE16 6.28 0.03625 0.380978042105263 GO:0031062 positive regulation of histone methylati... biological_process 32 11 BRCA1,CHTOP,CTR9,KMT2A,MTF2,MYB,OGT,PAX7,PAXBP1,PHF1,SMAD4 6.28 0.03625 0.380978042105263 GO:0032212 positive regulation of telomere maintena... biological_process 32 11 ATR,AURKB,CCT3,CCT7,MAP2K7,MAPKAPK5,NEK7,PNKP,POT1,TCP1,TNKS 6.28 0.03625 0.380978042105263 GO:0072583 clathrin-mediated endocytosis biological_process 32 11 AAK1,CLTA,FCHO1,FCHO2,FNBP1L,GAK,PIK3CB,PIP5K1C,SCYL2,SNAP91,TNK2 6.28 0.03625 0.380978042105263 GO:1904358 positive regulation of telomere maintena... biological_process 32 11 ATR,AURKB,CCT3,CCT7,MAP2K7,MAPKAPK5,NEK7,PNKP,POT1,TCP1,TNKS 6.28 0.03625 0.380978042105263 GO:0008643 carbohydrate transport biological_process 191 48 AAAS,ADIPOR2,AKT1,APPL1,AQP7,AQP8,ARPP19,ASPSCR1,BRAF,C2CD5,FABP5,GPC3,GRB10,IL1B,M6PR,MIP,NDC1,NFE2L2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OSBPL8,PIK3R2,PIK3R3,PRKCZ,RAE1,RANBP2,RAP1A,RPS6KB1,SEH1L,SIRT6,SLC25A27,SLC2A11,SLC2A5,SLC2A9,SLC35A1,SLC35B1,SLC45A1,SLC5A1,STXBP4,VIL1 37.5 0.03633 0.380978042105263 GO:0032922 circadian regulation of gene expression biological_process 56 17 AHR,ATF4,CIART,CREM,HDAC1,HDAC2,HNRNPU,KMT2A,LGR4,MAGED1,MTA1,NCOA2,OGT,PPP1CB,PPP1CC,PRMT5,RORC 11 0.03669 0.380978042105263 GO:0032984 macromolecular complex disassembly biological_process 223 55 ABCE1,ARHGEF2,ARID2,C12orf65,C16orf45,CAPZA1,CARMIL2,CLASP1,CLASP2,DAP3,GAK,GSN,HDAC6,HSPA8,MAP1S,MAP6D1,MCTS1,MID1IP1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTIF2,MTIF3,MTRF1,MTRF1L,NAPB,OGFOD1,PTCD3,SMARCD1,SMARCD2,SMARCE1,SPTB,SPTBN1,SPTBN4,STMN4,TFIP11,TRIOBP,TWF1,VIL1,VPS4A 43.78 0.03713 0.380978042105263 GO:0000381 regulation of alternative mRNA splicing,... biological_process 36 12 HNRNPL,RBM11,RBM25,RBM4,RBM7,RBMX,RNPS1,SAP18,SREK1,THRAP3,TRA2B,WTAP 7.07 0.03718 0.380978042105263 GO:0030212 hyaluronan metabolic process biological_process 36 12 AKT1,CD44,CLTC,EGF,HEXB,HMMR,HYAL1,HYAL3,IL15,IL1B,MKI67,TGFB1 7.07 0.03718 0.380978042105263 GO:0016441 posttranscriptional gene silencing biological_process 52 16 AGO1,AGO2,CNOT7,CNOT8,DICER1,DROSHA,EIF6,FXR1,HNRNPA2B1,LIMD1,PUM2,RBM4,SMAD2,TARBP2,TGFB1,ZCCHC11 10.21 0.03722 0.380978042105263 GO:0035194 posttranscriptional gene silencing by RN... biological_process 52 16 AGO1,AGO2,CNOT7,CNOT8,DICER1,DROSHA,EIF6,FXR1,HNRNPA2B1,LIMD1,PUM2,RBM4,SMAD2,TARBP2,TGFB1,ZCCHC11 10.21 0.03722 0.380978042105263 GO:0048522 positive regulation of cellular process biological_process 4512 927 AAK1,ABAT,ABCB4,ABI1,ABLIM3,ABR,ACACA,ACE,ACIN1,ACOD1,ACSL1,ACTR2,ACTR3C,ADA,ADAM10,ADCY10,ADCY4,ADCYAP1,ADGRD1,ADIPOR1,ADNP,ADORA1,AGO1,AGO2,AHR,AKAP12,AKNA,AKR1B1,AKT1,AKTIP,ALDH1A3,ALOX15,AMBRA1,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD49,ANKRD53,ANKRD6,ANO6,ANXA2,AP1G1,APBB1,APBB2,APH1A,ARF1,ARHGAP4,ARHGAP6,ARHGAP8,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID4A,ARIH1,ARL2BP,ARPC1A,ARPC1B,ARPP19,ASH1L,ASIC2,ASNS,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATMIN,ATOH8,ATP11C,ATP1B1,ATP2B4,ATP2C1,ATP6V1C2,ATR,ATRAID,ATRX,ATXN7,AURKA,AURKB,BAG4,BANP,BAX,BBC3,BCAR1,BCAS3,BCL2,BCLAF1,BICD1,BIRC3,BIRC6,BIRC7,BLK,BLNK,BMPR1B,BNIP2,BOC,BOK,BOLL,BPTF,BRAF,BRCA1,BRD4,BRD7,BRINP1,BRINP2,BTBD10,BTK,BUB1B,BUD31,C14orf166,C1QBP,C2,C2CD5,C4A,C4B,C5AR2,CACNA1H,CACNA2D1,CACUL1,CADPS2,CALCOCO2,CALM1,CAMK2A,CAMTA1,CAND1,CAPRIN1,CARF,CARMIL2,CASK,CASP8,CCDC80,CCDC88A,CCDC88B,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CD14,CD247,CD3G,CD44,CD46,CD6,CD74,CD81,CDC123,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDK13,CDK5RAP3,CDK7,CDON,CENPJ,CEP290,CFAP20,CFLAR,CHD1,CHD6,CHD7,CHFR,CHN1,CHRD,CHRNA3,CHRNA7,CHTOP,CHUK,CLASP1,CLASP2,CLDN7,CLEC4E,CLEC5A,CLIP1,CLU,CNOT2,CNOT7,CNOT8,CNST,CNTN1,COBL,COL4A3,CPEB3,CPNE1,CPNE3,CR1,CRACR2A,CREB5,CREM,CSF1R,CSNK2A1,CSNK2A3,CSPP1,CSRNP3,CTBP1,CTC1,CTDNEP1,CTNNA1,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CXCL12,CXCR2,CYBB,CYFIP1,CYLD,DAB2IP,DAPK1,DAPK3,DCAF6,DCTN1,DCUN1D4,DDB1,DDR2,DDX20,DDX39B,DDX56,DIABLO,DICER1,DKKL1,DMRT2,DNA2,DNAJA1,DNM1L,DNM3,DOCK7,DOT1L,DPP10,DUOXA1,DUSP9,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EAPP,EBF4,ECT2,EEF1D,EGF,EGFL7,EGFLAM,EGFR,EHD2,EIF2A,EIF2AK2,EIF4E,EIF6,ELF1,ELF3,ELP5,ELP6,EN1,ENPP2,ENY2,EPHA4,EPHB2,EPS8L1,ERC1,ESR1,ESRRB,ESRRG,ETV1,ETV5,ETV6,EVL,EXOC1,EXPH5,EYA3,EYA4,EZH2,FADD,FAF1,FAM110C,FAM150A,FAM58A,FANCI,FAS,FBLN2,FBXO22,FBXW11,FES,FEZ1,FGD3,FGD4,FGF5,FGFR1,FGFR1OP,FKBP6,FKBP8,FMN1,FNBP1L,FNTA,FOXJ1,FOXN3,FOXN4,FRS2,FXR1,FZR1,GABPB1,GADD45G,GBP5,GCLC,GDF9,GEN1,GIPR,GKN1,GLI1,GMFB,GMFG,GOLGA4,GPBP1,GPBP1L1,GPC1,GPC3,GPM6A,GPR35,GPRC5B,GRAP,GRB10,GRB7,GRHL1,GRHL2,GSK3B,GSN,GSTP1,GTF2B,GTF2H2,GTF2H3,GTF2H5,H2AFY,HACD3,HAP1,HAVCR2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC9,HEATR1,HEXB,HEYL,HIVEP3,HLA-DMB,HLA-DPB1,HLTF,HMGA2,HMGN1,HNRNPD,HNRNPK,HOXA10,HOXA7,HOXB1,HPRT1,HSF4,HSPA8,HSPD1,HSPH1,HTR2B,HYAL1,ICE1,ICE2,IDO1,IGF1R,IGF2R,IGFBP2,IL15,IL1B,IL2RA,IL4R,IMPACT,INO80,IP6K2,IRAK1,IRAK4,IRF2,IRF5,ITGA2,ITGA6,ITGAV,ITGB1BP1,ITGB3BP,ITM2C,ITSN2,JADE1,JUND,KALRN,KANK1,KAT2B,KAT6A,KAT7,KCNB1,KCNMA1,KDM7A,KIAA1524,KIF23,KLF6,KMT2A,KMT2D,KMT2E,KRAS,LAMC2,LAMTOR1,LAMTOR3,LANCL2,LAT,LCP1,LDLRAP1,LEO1,LFNG,LGI1,LGR4,LGR5,LIF,LIG4,LIMD1,LIMK1,LIMS2,LITAF,LMO2,LMO3,LPIN1,LRP6,LRRTM1,LRRTM3,LTA,LTBP3,LTF,LYL1,MADD,MAFK,MAGED1,MALT1,MAN2A1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARCH5,MBD5,MBTPS2,MCAM,MCF2,MCF2L,MCTS1,MDM2,MDM4,MED12L,MED13,MED14,MED16,MED21,MED24,MED30,MEF2A,MEF2C,MEIS2,MELK,METRN,MFF,MFGE8,MFNG,MIA3,MID1IP1,MIER1,MINK1,MIP,MNAT1,MOB2,MOSPD1,MST1R,MSX2,MTBP 885.88 0.03732 0.380978042105263 GO:0060271 cilium morphogenesis biological_process 214 53 ABLIM3,ACTR2,ARL6,ARMC4,ATMIN,ATP6V0D1,ATXN10,BBS1,BBS2,CCDC114,CEP164,CEP290,CEP89,CFAP100,CFAP20,CFAP221,CFAP46,CFAP73,DNAI1,DNAI2,DRC1,FAM161A,FBF1,FNBP1L,FOXJ1,GALNT11,GSN,HSPB11,IQCB1,IQCG,MKS1,NME5,OCRL,OFD1,ONECUT2,PCM1,POC1B,RAB1A,RFX2,RPGR,RSPH9,SEPT2,SEPT7,SPAG16,SSX2IP,TAPT1,TMEM237,TMEM67,TPGS1,TROVE2,TTC21B,UBE2B,WWTR1 42.02 0.03741 0.380978042105263 GO:0009112 nucleobase metabolic process biological_process 40 13 ADA,APRT,CECR1,CMPK1,CPS1,DPYS,GART,GDA,GMPS,HPRT1,MTOR,TYMS,UPRT 7.85 0.03765 0.380978042105263 GO:0018279 protein N-linked glycosylation via aspar... biological_process 40 13 DAD1,DDOST,FUT8,MCFD2,OSTC,RPN2,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,UBE2G2,UGGT2 7.85 0.03765 0.380978042105263 GO:0032480 negative regulation of type I interferon... biological_process 40 13 ACOD1,CYLD,HAVCR2,HERC5,NLRC5,NMI,PCBP2,PIN1,PPM1B,RNF216,TAX1BP1,TBK1,UBA52 7.85 0.03765 0.380978042105263 GO:0010501 RNA secondary structure unwinding biological_process 44 14 AGO1,AGO2,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,EIF4A1,EIF4A2 8.64 0.03776 0.380978042105263 GO:0070265 necrotic cell death biological_process 44 14 ARHGEF2,BIRC3,CASP8,CD14,CFLAR,CYLD,DNM1L,FADD,RBCK1,SIRT2,TRADD,TRPM7,UBA52,YBX3 8.64 0.03776 0.380978042105263 GO:0030307 positive regulation of cell growth biological_process 129 34 ADAM10,ADNP,AKT1,BCL2,CDC42,CSNK2A1,CSNK2A3,CXCL12,DDX39B,EGFR,FGFR1OP,GOLGA4,GSK3B,HYAL1,INO80,LGI1,LIMK1,MAP2K5,MTOR,NOL8,NTRK3,PAFAH1B1,PIN1,PRSS2,PTK2B,RPS6KA1,RUFY3,SDCBP,SEMA4D,SEMA7A,SHTN1,SLC44A4,TGFBR1,VEGFA 25.33 0.03793 0.380978042105263 GO:0050767 regulation of neurogenesis biological_process 636 143 ADCYAP1,ADNP,AKT1,APBB1,ARF1,ARHGAP4,ARHGEF1,ARHGEF2,BCL2,BRAF,BRINP1,BRINP2,C16orf45,CACNA1A,CAPRIN1,CCDC88A,CDK5RAP3,CDON,CERS2,CHD7,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CPNE1,CTNNA1,CUX1,CXCL12,DAB2IP,DCC,DDX56,DDX6,DICER1,DNM3,DOCK7,DTX1,DUOXA1,ECT2,EIF4E,EMX1,EPHA4,EPHB2,ETV5,EZH2,FAM150A,FBXO7,FES,FEZ1,FGFR1,FKBP4,FUOM,GAK,GOLGA4,GORASP1,GPRC5B,GSK3B,HAP1,HDAC1,HDAC2,HEYL,IFRD1,IMPACT,ITM2C,KALRN,KANK1,KEL,KLK8,LBX1,LIF,LIG4,LIMK1,LTA,MAN2A1,MAPK8IP3,MDM2,MEF2C,METRN,MOB2,MTOR,NCK1,NCKIPSD,NCOA1,NEPRO,NF1,NFE2L2,NLGN3,NREP,NTRK2,NTRK3,OLFM1,OPA1,OPRM1,PAFAH1B1,PAK3,PAQR3,PBX1,PCM1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRMT5,PRRX1,PTEN,PTK2,PTK2B,RAP1A,RAP1GAP2,RAPGEF2,RELN,RGMA,RGS14,RNF6,ROBO1,RTN4,RUFY3,S1PR5,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SIRT2,SIX1,SIX3,SKIL,SNAPIN,SORL1,SPAG9,STAR,STK25,TCF12,TGFB1,THY1,UFL1,ULK2,VEGFA,XRCC5,ZEB1 124.87 0.03793 0.380978042105263 GO:0033674 positive regulation of kinase activity biological_process 484 111 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AMBRA1,ATP2B4,BAX,BIRC7,BRAF,CACUL1,CALM1,CCDC88A,CCNC,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CHRNA3,CHRNA7,CSF1R,DAB2IP,DDR2,DUSP9,ECT2,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FAM150A,FAM58A,FGFR1,FRS2,GADD45G,GPRC5B,HACD3,HSPH1,HTR2B,IGF1R,IL1B,IRAK1,ITGB1BP1,KRAS,LAMTOR3,LAT,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NOX4,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PDCD10,PDE5A,PDGFRB,PFKFB1,PIK3CA,PIK3CB,PIK3R5,PPP2R3C,PRKAR2A,PRKCZ,PRLR,PTK2,PTK2B,RALB,RAP1A,RAPGEF2,RELN,SASH1,SHC2,SNX9,SPAG9,SPDYA,TAB2,TAB3,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TOM1L1,TRAF4,UBA52,VEGFA,WNT11,ZP4 95.03 0.03799 0.380978042105263 GO:0031399 regulation of protein modification proce... biological_process 1666 355 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKLE2,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARL2BP,ARPP19,ASH1L,ATP2B4,ATRX,BAG4,BAX,BCCIP,BCL2,BIRC3,BIRC7,BRAF,BRCA1,BRD4,BRD7,BUB1B,C3orf33,C5AR2,CACUL1,CALM1,CAMSAP3,CCDC88A,CCDC88C,CCL25,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD44,CD74,CD81,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK12,CDK5RAP3,CDK7,CDKN3,CDON,CEP192,CHAD,CHFR,CHORDC1,CHRNA3,CHRNA7,CHTOP,CLU,CNST,CNTN1,CSF1R,CSRNP3,CTBP1,CTR9,CUL1,DAB2IP,DAG1,DCUN1D4,DDR2,DLG2,DLG3,DNAJA1,DNAJC10,DOCK7,DUSP16,DUSP9,DYNC1LI1,ECT2,EGF,EGFR,EIF2AK2,ELP4,ENPP2,EPHA4,EZH2,FAF1,FAM150A,FAM58A,FANCI,FARP1,FAS,FBXO22,FBXO7,FGFR1,FGFR1OP,FNTA,FRS2,FZR1,GADD45G,GCLC,GDF9,GEN1,GFRA2,GMFB,GMFG,GPRC5B,GSK3B,GSTP1,H2AFY,HACD3,HAVCR2,HDAC1,HDAC2,HDAC8,HERC5,HGS,HHATL,HIPK3,HSP90B1,HSPH1,HTR2B,HUS1,IGF1R,IL15,IL1B,IL22RA2,IMPACT,IRAK1,ITGA2,ITGB1BP1,KAT2B,KLHL40,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LCMT1,LIF,LIMK1,LMO3,LRP6,LRRTM1,LRRTM3,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8,MAPK8IP3,MAPKAPK5,MARVELD3,MASTL,MEF2C,MINK1,MNAT1,MOB2,MPHOSPH10,MST1R,MTF2,MTOR,MVP,MYB,MYOC,N4BP1,NCK1,NCOR1,NDRG2,NEK10,NF1,NIPBL,NLRP12,NOX1,NOX4,NTRK2,NTRK3,OGT,OPRK1,OPRM1,OSBPL8,PAFAH1B1,PAK1,PAK2,PAK3,PAQR3,PARP10,PAX7,PAXBP1,PBK,PDCD10,PDCL3,PDE4D,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PHIP,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PLA2G5,PLCB1,PODN,PPP1R12A,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R3C,PPP2R5C,PPP2R5E,PPP6R3,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRMT3,PRMT5,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PSMG2,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTTG1IP,PUM3,RAC2,RALB,RAP1A,RAP1B,RAPGEF2,RBPMS,RCHY1,RELN,RELT,RGN,RGS14,RGS3,RNF4,ROS1,RPS6KA6,RTN4RL2,SASH1,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SHC2,SIRT2,SMAD4,SMYD3,SNX9,SORBS3,SORL1,SPAG9,SPDYA,SPRTN,SPRY1,SPTBN4,STAP2,STK25,STRAP,SYTL2,TAB2,TAB3,TARBP2,TBC1D10C,TBK1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TLR7,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNK2,TOM1L1,TRAF4,TRIM5,TRIP12,TTK,TWF1,UBA52,UBE2B,UBE2E1,UBE3A,UFL1,USP4,UVRAG,VEGFA,WNT11,WWTR1,XIAP,XRCC3,ZC3H12A,ZNF207,ZNF451,ZP4 327.1 0.03823 0.380978042105263 GO:0045664 regulation of neuron differentiation biological_process 522 119 ADCYAP1,ADNP,AKT1,APBB1,ARF1,ARHGAP4,ARHGEF1,BCL2,BRAF,BRINP1,BRINP2,CACNA1A,CAPRIN1,CCDC88A,CDK5RAP3,CDON,CERS2,CHN1,CHODL,CHRNA3,CLIP1,CNTN1,COBL,CPEB3,CPNE1,CUX1,CXCL12,DAB2IP,DCC,DDX56,DDX6,DNM3,DTX1,DUOXA1,ECT2,EIF4E,EPHA4,EPHB2,ETV5,EZH2,FAM150A,FBXO7,FES,FEZ1,FGFR1,FKBP4,FUOM,GAK,GOLGA4,GORASP1,GPRC5B,GSK3B,HDAC2,HEYL,IFRD1,IMPACT,ITM2C,KALRN,KANK1,KEL,KLK8,LBX1,LIMK1,MAPK8IP3,MDM2,MEF2C,METRN,MOB2,MTOR,NCK1,NCKIPSD,NCOA1,NEPRO,NFE2L2,NLGN3,NREP,NTRK2,NTRK3,OLFM1,OPA1,PAFAH1B1,PAK3,PAQR3,PBX1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PRRX1,PTEN,PTK2,PTK2B,RAP1A,RAP1GAP2,RAPGEF2,RELN,RGMA,RNF6,ROBO1,RTN4,RUFY3,S1PR5,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SIX1,SIX3,SKIL,SNAPIN,SPAG9,STK25,TCF12,THY1,ULK2,VEGFA,ZEB1 102.49 0.03826 0.380978042105263 GO:0000105 histidine biosynthetic process biological_process 2 2 MTHFD1,MTHFD2L 0.39 0.03854 0.380978042105263 GO:0000912 assembly of actomyosin apparatus involve... biological_process 2 2 KIF23,RACGAP1 0.39 0.03854 0.380978042105263 GO:0000915 actomyosin contractile ring assembly biological_process 2 2 KIF23,RACGAP1 0.39 0.03854 0.380978042105263 GO:0000964 mitochondrial RNA 5-end processing biological_process 2 2 PNPT1,TRMT10C 0.39 0.03854 0.380978042105263 GO:0000973 posttranscriptional tethering of RNA pol... biological_process 2 2 NUP107,NUP98 0.39 0.03854 0.380978042105263 GO:0002368 B cell cytokine production biological_process 2 2 BTK,HSPD1 0.39 0.03854 0.380978042105263 GO:0003220 left ventricular cardiac muscle tissue m... biological_process 2 2 RYR2,SMAD4 0.39 0.03854 0.380978042105263 GO:0006436 tryptophanyl-tRNA aminoacylation biological_process 2 2 WARS,WARS2 0.39 0.03854 0.380978042105263 GO:0006500 N-terminal protein palmitoylation biological_process 2 2 HHATL,MAP6D1 0.39 0.03854 0.380978042105263 GO:0007525 somatic muscle development biological_process 2 2 NEB,NKD1 0.39 0.03854 0.380978042105263 GO:0010968 regulation of microtubule nucleation biological_process 2 2 DCTN1,EML2 0.39 0.03854 0.380978042105263 GO:0016340 calcium-dependent cell-matrix adhesion biological_process 2 2 DAG1,TRPM7 0.39 0.03854 0.380978042105263 GO:0018931 naphthalene metabolic process biological_process 2 2 AKR1B1,CYP2F1 0.39 0.03854 0.380978042105263 GO:0019255 glucose 1-phosphate metabolic process biological_process 2 2 PGM3,UGP2 0.39 0.03854 0.380978042105263 GO:0019853 L-ascorbic acid biosynthetic process biological_process 2 2 AKR1A1,RGN 0.39 0.03854 0.380978042105263 GO:0021896 forebrain astrocyte differentiation biological_process 2 2 KRAS,NF1 0.39 0.03854 0.380978042105263 GO:0021897 forebrain astrocyte development biological_process 2 2 KRAS,NF1 0.39 0.03854 0.380978042105263 GO:0031635 adenylate cyclase-inhibiting opioid rece... biological_process 2 2 OPRK1,OPRM1 0.39 0.03854 0.380978042105263 GO:0032472 Golgi calcium ion transport biological_process 2 2 ATP2C1,TMEM165 0.39 0.03854 0.380978042105263 GO:0032915 positive regulation of transforming grow... biological_process 2 2 ATF2,WNT11 0.39 0.03854 0.380978042105263 GO:0035261 external genitalia morphogenesis biological_process 2 2 LRP6,NIPBL 0.39 0.03854 0.380978042105263 GO:0035262 gonad morphogenesis biological_process 2 2 LHX9,SMAD4 0.39 0.03854 0.380978042105263 GO:0035983 response to trichostatin A biological_process 2 2 EZH2,MEF2C 0.39 0.03854 0.380978042105263 GO:0035984 cellular response to trichostatin A biological_process 2 2 EZH2,MEF2C 0.39 0.03854 0.380978042105263 GO:0036228 protein targeting to nuclear inner membr... biological_process 2 2 NUP155,NUP54 0.39 0.03854 0.380978042105263 GO:0038063 collagen-activated tyrosine kinase recep... biological_process 2 2 DDR1,DDR2 0.39 0.03854 0.380978042105263 GO:0042323 negative regulation of circadian sleep/w... biological_process 2 2 ADA,ADORA1 0.39 0.03854 0.380978042105263 GO:0044209 AMP salvage biological_process 2 2 ADK,APRT 0.39 0.03854 0.380978042105263 GO:0044565 dendritic cell proliferation biological_process 2 2 AZI2,TBK1 0.39 0.03854 0.380978042105263 GO:0044837 actomyosin contractile ring organization biological_process 2 2 KIF23,RACGAP1 0.39 0.03854 0.380978042105263 GO:0051977 lysophospholipid transport biological_process 2 2 MFSD2A,PLA2G10 0.39 0.03854 0.380978042105263 GO:0060327 cytoplasmic actin-based contraction invo... biological_process 2 2 SHTN1,VIL1 0.39 0.03854 0.380978042105263 GO:0060382 regulation of DNA strand elongation biological_process 2 2 NUCKS1,POT1 0.39 0.03854 0.380978042105263 GO:0060701 negative regulation of ribonuclease acti... biological_process 2 2 ABCE1,TMBIM6 0.39 0.03854 0.380978042105263 GO:0060702 negative regulation of endoribonuclease ... biological_process 2 2 ABCE1,TMBIM6 0.39 0.03854 0.380978042105263 GO:0070124 mitochondrial translational initiation biological_process 2 2 MTIF2,MTIF3 0.39 0.03854 0.380978042105263 GO:0070256 negative regulation of mucus secretion biological_process 2 2 ADA,ADORA1 0.39 0.03854 0.380978042105263 GO:0071140 resolution of mitotic recombination inte... biological_process 2 2 GEN1,XRCC3 0.39 0.03854 0.380978042105263 GO:0090118 receptor-mediated endocytosis of low-den... biological_process 2 2 LDLRAP1,LRP6 0.39 0.03854 0.380978042105263 GO:0090149 mitochondrial membrane fission biological_process 2 2 DNM1L,SLC25A46 0.39 0.03854 0.380978042105263 GO:0090420 naphthalene-containing compound metaboli... biological_process 2 2 AKR1B1,CYP2F1 0.39 0.03854 0.380978042105263 GO:0097010 eukaryotic translation initiation factor... biological_process 2 2 EIF4B,EIF4H 0.39 0.03854 0.380978042105263 GO:0097069 cellular response to thyroxine stimulus biological_process 2 2 GCLC,GCLM 0.39 0.03854 0.380978042105263 GO:0097460 ferrous iron import into cell biological_process 2 2 TF,TFR2 0.39 0.03854 0.380978042105263 GO:1900195 positive regulation of oocyte maturation biological_process 2 2 AURKA,SIRT2 0.39 0.03854 0.380978042105263 GO:1900220 semaphorin-plexin signaling pathway invo... biological_process 2 2 PLXNB1,SEMA4D 0.39 0.03854 0.380978042105263 GO:1901664 regulation of NAD+ ADP-ribosyltransferas... biological_process 2 2 HMGN1,TGFB1 0.39 0.03854 0.380978042105263 GO:1901666 positive regulation of NAD+ ADP-ribosylt... biological_process 2 2 HMGN1,TGFB1 0.39 0.03854 0.380978042105263 GO:1903975 regulation of glial cell migration biological_process 2 2 C16orf45,CERS2 0.39 0.03854 0.380978042105263 GO:1903976 negative regulation of glial cell migrat... biological_process 2 2 C16orf45,CERS2 0.39 0.03854 0.380978042105263 GO:1904387 cellular response to L-phenylalanine der... biological_process 2 2 GCLC,GCLM 0.39 0.03854 0.380978042105263 GO:2000625 regulation of miRNA catabolic process biological_process 2 2 PNPT1,ZC3H12A 0.39 0.03854 0.380978042105263 GO:2000627 positive regulation of miRNA catabolic p... biological_process 2 2 PNPT1,ZC3H12A 0.39 0.03854 0.380978042105263 GO:2000777 positive regulation of proteasomal ubiqu... biological_process 2 2 PLK3,SIRT2 0.39 0.03854 0.380978042105263 GO:2001033 negative regulation of double-strand bre... biological_process 2 2 HMGA2,TFIP11 0.39 0.03854 0.380978042105263 GO:0045740 positive regulation of DNA replication biological_process 90 25 ATR,ATRX,AURKB,CCT3,CCT7,CDC42,CTC1,DNA2,E2F7,EGFR,GLI1,GRHL2,IGF1R,INO80,MAP2K4,MAP2K7,MAPKAPK5,NEK7,NPM2,NVL,PNKP,POT1,TCP1,TNKS,WIZ 17.67 0.03862 0.381325574112735 GO:0031100 organ regeneration biological_process 73 21 ANGPT2,ATIC,AURKA,CXCL12,EGFR,EZH2,GLI1,GSTP1,IGF2R,LCP1,LPIN1,MKI67,PFKFB1,PRMT5,RAP1A,RGN,RPL32,SRSF5,TGFB1,TYMS,UGT1A1 14.33 0.03870 0.381325574112735 GO:0006119 oxidative phosphorylation biological_process 103 28 COX5A,COX6A1,COX7A2L,DLD,GBAS,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHAF2,SDHC,SURF1,TAZ,TEFM,UQCRB,UQCRC2,UQCRH 20.22 0.03889 0.381325574112735 GO:0007020 microtubule nucleation biological_process 21 8 CENPJ,CLASP1,CLASP2,DCTN1,EML2,NDE1,SLAIN2,TUBGCP5 4.12 0.03890 0.381325574112735 GO:0007064 mitotic sister chromatid cohesion biological_process 21 8 H2AFY,MAU2,NIPBL,NSMCE2,PDS5B,SLF1,SMC1A,WAPL 4.12 0.03890 0.381325574112735 GO:0042347 negative regulation of NF-kappaB import ... biological_process 21 8 CYLD,FAF1,FBXW11,LITAF,NLRP12,PPM1B,TRIP6,ZC3H12A 4.12 0.03890 0.381325574112735 GO:0044818 mitotic G2/M transition checkpoint biological_process 21 8 CDK5RAP3,FANCI,FOXN3,HMGA2,HUS1,NAE1,SLF1,TOPBP1 4.12 0.03890 0.381325574112735 GO:0072600 establishment of protein localization to... biological_process 21 8 ATP9B,GAK,GCC2,GOLGA4,NRAS,RGPD1,RGPD5,SORL1 4.12 0.03890 0.381325574112735 GO:0007015 actin filament organization biological_process 325 77 ABI1,ACTN1,ACTR2,ACTR3C,AKAP2,ALOX15,ARF1,ARHGAP6,ARHGEF15,ARHGEF2,ARPC1A,ARPC1B,BAG4,BCAR1,BCL2,BRAF,CAPZA1,CARMIL2,CATIP,CDC42,CDC42EP3,CLASP1,CLASP2,COBL,CORO7,CTNNA1,CUL3,CXCL12,CYFIP1,EVL,FAT1,FCHSD1,FHOD3,FMN1,FMN2,FRY,FRYL,GMFB,GMFG,GSN,HSP90B1,ITGB1BP1,KANK1,LCP1,LIMK1,MTOR,MYO1B,MYOC,NCK1,NOX4,PAK1,PAK3,PAWR,PDCD10,PDLIM3,PFN2,PICK1,PTK2B,RAC2,RHOF,RUFY3,SORBS2,SORBS3,SPTB,SPTBN1,SPTBN4,SYNPO,SYNPO2,TGFBR1,TMEFF2,TNNT2,TRIOBP,TTC17,TWF1,VIL1,WNT11,ZYX 63.81 0.03898 0.381711345151199 GO:0031570 DNA integrity checkpoint biological_process 156 40 ATF2,ATR,AURKA,BAX,BRCA1,BRIP1,CDC14B,CDC6,CDK5RAP3,CENPJ,CEP63,CNOT2,CNOT7,CNOT8,DDX39B,DNA2,DOT1L,E2F7,FANCI,FOXN3,FZR1,GIGYF2,HMGA2,HUS1,MDM2,MDM4,NAE1,NEK11,PCBP4,PLK3,PRMT1,RAD17,RBBP8,RFWD3,SLF1,THOC1,TOPBP1,TP63,UBA52,ZNF385A 30.63 0.03937 0.385128822916667 GO:0045333 cellular respiration biological_process 165 42 COX20,COX5A,COX6A1,COX7A2L,CS,DLAT,DLD,ETFA,IMMP2L,LYRM5,MDH1,MT-CO1,MT-CO2,MT-CO3,MTFR1,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NNT,PDHB,PIK3CA,PMPCB,PNPT1,PRDM16,SDHAF2,SDHC,SDHD,SLC25A13,SUCLG1,SURF1,TAZ,UQCRB,UQCRC2,UQCRH 32.4 0.03955 0.386487044745057 GO:0030031 cell projection assembly biological_process 358 84 ABLIM3,ACTR2,ANO6,ARL6,ARMC4,ATP6V0D1,ATXN10,BAG4,BBS1,BBS2,BCAS3,CARMIL2,CCDC114,CCDC88A,CDC42,CDC42EP3,CDH13,CEP164,CEP290,CEP89,CFAP100,CFAP46,CFAP73,COBL,CYFIP1,DNAI1,DNAI2,DNM3,DRC1,EPS8L1,EVL,FAM110C,FAM161A,FBF1,FGD3,FGD4,FGD6,FNBP1L,FOXJ1,GPM6A,HSPB11,IQCB1,IQCG,ITGA6,KANK1,MINK1,MKS1,MTOR,MYH10,MYLK,MYO10,NCK1,NME5,OCRL,ONECUT2,P2RY12,PCM1,PFN2,PIP5K1A,PLD1,POC1B,RAB1A,RAB5A,RAC2,RAP1A,RAP1B,RAPGEF2,RFX2,RPGR,RSPH9,SDCBP,SEPT2,SH3YL1,SHTN1,SPAG16,SPATA13,SSX2IP,TAPT1,TGFBR1,TMEM237,TMEM67,TPGS1,TTYH1,UBE2B 70.29 0.03991 0.389599594594595 GO:0006140 regulation of nucleotide metabolic proce... biological_process 892 196 ABR,ACAP1,ACAP2,ADCY4,ADCYAP1,ADGRD1,ADNP,ADPRHL1,AGFG1,AHSA2,AIPL1,AKAP12,AMPH,APLP1,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF2,ATP1B1,BCAS3,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42EP3,CHN1,CHTOP,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,EGFR,EIF6,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GABBR1,GCGR,GDI2,GFRA2,GIPR,GMIP,GRM7,GRM8,GSK3B,HACD3,HNRNPU,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,LLGL2,LTF,MADD,MCF2,MCF2L,METTL21A,MTOR,NCK1,NCOR1,NF1,NOS3,NPRL3,NTRK2,OCRL,OGT,OPRM1,P2RY12,PAFAH1B1,PDE2A,PDE4D,PDE5A,PDE6D,PDGFRB,PDZD3,PFN2,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTK2B,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RP2,RPGR,RUNDC1,RYR2,SBF1,SEMA4D,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SIRT6,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,SUMO1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TBL1XR1,THY1,TIGAR,TLR9,TMED2,TNK2,TNNI3,TNNT2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,TSHR,USP6NL,VAV1,VEGFA,WNT11 175.13 0.04009 0.390950353063344 GO:0031054 pre-miRNA processing biological_process 14 6 AGO1,AGO2,DICER1,DROSHA,TARBP2,ZCCHC11 2.75 0.04034 0.392166604554865 GO:0031116 positive regulation of microtubule polym... biological_process 14 6 ANKRD53,CLASP1,CLIP1,DCTN1,FES,SLAIN2 2.75 0.04034 0.392166604554865 GO:0048313 Golgi inheritance biological_process 14 6 PDCD10,PLK3,STK25,STX5,VCPIP1,YWHAZ 2.75 0.04034 0.392166604554865 GO:0030433 ER-associated ubiquitin-dependent protei... biological_process 65 19 DNAJC10,EDEM3,HSP90B1,JKAMP,NPLOC4,POMT2,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RNF121,SEC61B,TMEM67,UBE2G2,UBE2J2,UBE4A,UBXN4,UGGT2 12.76 0.04096 0.397371239669422 GO:0051492 regulation of stress fiber assembly biological_process 65 19 ARHGAP6,ARHGEF15,BAG4,BRAF,CLASP1,CLASP2,EVL,ITGB1BP1,LIMK1,MTOR,MYOC,NOX4,PAK1,PFN2,SORBS3,SYNPO,TGFBR1,TMEFF2,WNT11 12.76 0.04096 0.397371239669422 GO:0010770 positive regulation of cell morphogenesi... biological_process 161 41 ADNP,BRAF,C1QBP,CAPRIN1,CDC42,CUX1,CXCL12,EPHA4,EZH2,GOLGA4,GSK3B,HDAC2,KALRN,LIF,LIMK1,METRN,MYOC,NTRK2,NTRK3,OLFM1,PAFAH1B1,PAK3,PAX2,PLXNB1,RELN,ROBO1,RUFY3,SDCBP,SEMA4D,SEMA7A,SHTN1,SKIL,SMAD2,SMAD4,STK25,TGFB1,TGFB1I1,TGFBR1,TRIOBP,VEGFA,WWTR1 31.61 0.04130 0.400256243550052 GO:1903046 meiotic cell cycle process biological_process 179 45 ACTR2,AURKA,BOLL,CCNA1,DMC1,DPEP3,DUSP13,FANCA,FANCD2,FKBP6,FMN2,FZR1,HORMAD1,LFNG,LIF,MASTL,MKI67,MSH5,MSX2,MYH9,NDC1,NPM2,PLCB1,PPP2R1A,RAD51C,RAD54B,RAD54L,RNF212,SGO1,SIRT2,SMC1A,SMC2,SMC4,SPDYA,STAG3,SYCP3,TERB2,TEX11,TEX14,TOP2B,TUBB8,TUBGCP5,UBE2B,WAPL,XRCC3 35.14 0.04135 0.400327680412371 GO:0006650 glycerophospholipid metabolic process biological_process 340 80 ABHD3,ALOX15,AMBRA1,ARF1,BPNT1,CD81,CDC42,CDS2,CPNE1,CPNE3,CRLS1,CSF1R,DAB2IP,DBI,DGKA,EFR3A,EGF,EGFR,ENPP2,ETNK1,FABP5,FAR1,FGF5,FGFR1,FRS2,GNPAT,HRASLS5,HTR2B,INPP1,INPP5A,INPP5B,IP6K2,LPCAT3,LPCAT4,LPGAT1,LPIN1,MPPE1,MTMR1,MTMR7,OCRL,PAFAH1B1,PCYT1A,PDGFRB,PGAP1,PGAP3,PIGA,PIGN,PIGQ,PIGT,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIP5K1A,PIP5K1C,PLA2G10,PLA2G4B,PLA2G4C,PLA2G5,PLBD1,PLCB1,PLCD4,PLD1,PON1,PTDSS1,PTEN,PTK2,PTK2B,SACM1L,SERINC3,SH3YL1,SLC44A4,SMG1,TAZ,TGFB1,TLR9,VAV1 66.76 0.04155 0.401849691040165 GO:0071156 regulation of cell cycle arrest biological_process 252 61 ATF2,ATR,AURKA,AURKB,BAX,BRCA1,BRIP1,BUB1B,CCNE2,CDC14B,CDC6,CDK5RAP3,CENPJ,CEP63,CHFR,CNOT2,CNOT7,CNOT8,CSNK2A1,CSNK2A2,DAB2IP,DDX39B,DNA2,DOT1L,DYNC1LI1,E2F7,FANCI,FOXN3,FZR1,GEN1,GIGYF2,HMGA2,HORMAD1,HUS1,KNTC1,LCMT1,MDM2,MDM4,NAE1,NEK11,PCBP4,PLK3,PRMT1,PSMG2,RAD17,RBBP8,RFWD3,RRP8,SLF1,SMC1A,SPDL1,TEX14,TGFB1,THOC1,TOPBP1,TP63,TTK,UBA52,XRCC3,ZNF207,ZNF385A 49.48 0.04161 0.402015956790123 GO:0034249 negative regulation of cellular amide me... biological_process 108 29 AGO1,AGO2,ATF4,CAPRIN1,CNOT2,CPEB1,CPEB3,DAPK1,DAPK3,EIF2AK2,EIF4E,EIF6,EPRS,FXR1,GIGYF2,GRB7,HAP1,HNRNPD,IGF2BP3,MALSU1,METTL14,ORMDL2,ORMDL3,PAIP2,PURA,RBM4,TIA1,UNK,ZC3H12A 21.2 0.04185 0.40358254601227 GO:0000470 maturation of LSU-rRNA biological_process 25 9 EIF6,MRPL1,NOP2,NSA2,RPF1,RPF2,RPL7L1,SNU13,WDR12 4.91 0.04198 0.40358254601227 GO:0032365 intracellular lipid transport biological_process 25 9 ABCA2,ACACA,CES1,CPT2,LDLRAP1,LRP6,STAR,STARD4,VPS4A 4.91 0.04198 0.40358254601227 GO:0034243 regulation of transcription elongation f... biological_process 25 9 BRD4,CTR9,EAPP,EZH2,LEO1,RECQL5,RNF8,SUPT4H1,TCEB1 4.91 0.04198 0.40358254601227 GO:0035384 thioester biosynthetic process biological_process 61 18 ACACA,ACAT1,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,DLAT,DLD,ELOVL6,ELOVL7,HACD1,PDHB,PDK3,PPT2,SCD5,TECR 11.98 0.04203 0.40358254601227 GO:0071616 acyl-CoA biosynthetic process biological_process 61 18 ACACA,ACAT1,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,DLAT,DLD,ELOVL6,ELOVL7,HACD1,PDHB,PDK3,PPT2,SCD5,TECR 11.98 0.04203 0.40358254601227 GO:0012501 programmed cell death biological_process 1724 366 ABR,ACIN1,ACTN1,ADA,ADCY10,ADCYAP1,ADNP,ADORA1,AHR,AIFM3,AIPL1,AKT1,AKTIP,ALDH1A3,AMBRA1,ANKLE2,ANO6,ANP32A,ANXA4,ANXA6,APBB1,APBB2,APH1A,APLP1,APPL1,ARHGAP4,ARHGEF12,ARHGEF16,ARHGEF2,ASIC2,ASNS,ATF2,ATF4,ATG3,AURKA,AURKB,BAG4,BAX,BBC3,BCAR1,BCL2,BCL2L14,BCL7C,BCLAF1,BIRC3,BIRC6,BIRC7,BLCAP,BLK,BNIP2,BOK,BRAF,BRCA1,BTK,BUB1B,C19orf68,C1D,C1QBP,C3orf38,C6orf120,CACNA1A,CAMK2A,CARD16,CASP4,CASP8,CD14,CD3G,CD44,CD74,CDC42,CDK11A,CDK5RAP3,CEACAM5,CFLAR,CHL1,CHMP3,CLDN7,CLEC5A,CLN3,CLU,COL4A3,CRYAB,CSE1L,CSF1R,CSNK2A1,CSNK2A2,CSRNP3,CTNNA1,CTNNBL1,CUL1,CUL3,CXCL12,CXCR2,CYLD,DAB2IP,DAD1,DAP3,DAPK1,DAPK3,DAPL1,DCC,DDB1,DDIAS,DDX20,DDX47,DHRS2,DIABLO,DICER1,DMPK,DNAJA1,DNAJC10,DNASE1,DNM1L,DPF1,DRAM2,DYRK2,EAF2,ECT2,EGFR,EI24,EIF2AK2,EN1,EPB41L3,ERN2,ERO1A,ESR1,ETV6,EVA1A,EYA3,EYA4,FADD,FAF1,FAS,FASTK,FGD3,FGD4,FGFR1,FIGNL1,FKBP8,FMN2,FNTA,FRS2,FXR1,G2E3,GABRA5,GADD45G,GCLC,GCLM,GDF9,GGCT,GLRX2,GLS2,GNGT1,GSK3B,GSN,GSTP1,HAP1,HDAC1,HDAC2,HDAC6,HIPK3,HMGA2,HNRNPK,HSP90B1,HSPD1,HTR2B,IDO1,IGF1R,IGF2R,IL1B,IL2RA,IP6K2,IRAK1,IRF5,ITGA6,ITGAV,ITGB3BP,ITM2C,ITPR1,JADE1,KALRN,KANK2,KCNB1,KCNMA1,KLHL20,KMT2A,KRAS,KRIT1,LCMT1,LCN2,LIG4,LIMS2,LITAF,LRP6,LTA,LTF,MADD,MAEA,MAGED1,MALT1,MAP1S,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAPK8,MCF2,MCF2L,MDM2,MDM4,MEF2A,MEF2C,MELK,MFF,MNAT1,MRPL41,MRPS30,MSX2,MTCH1,MTDH,MYO18A,NAA16,NAE1,NCOA1,NF1,NFE2L2,NFKBID,NISCH,NLRP12,NME4,NME6,NMT1,NOX4,NOX5,NR3C1,NSMAF,NTRK2,NTRK3,OGT,OPA1,PACS2,PAK1,PAK2,PAK3,PARP2,PAWR,PAX2,PAX3,PAX4,PAX7,PDCD10,PDCD2,PDCD5,PDCL3,PDE1B,PDGFRB,PHIP,PIAS1,PIGT,PIK3CA,PIN1,PKM,PLEKHG2,PLK3,POLB,POLR2G,POR,PPP2R1A,PRKCZ,PRLR,PSMC5,PSME3,PSMG2,PTEN,PTK2,PTK2B,PTPN6,PTRH2,RABEP1,RABGGTB,RALB,RAPGEF2,RAPSN,RASSF6,RBCK1,RBM25,RELT,RGN,RHBDD1,RHOT1,RNF216,RNPS1,ROBO1,RPS6KA1,RPS6KB1,RRP8,RTN3,RTN4,RYR2,SAP18,SAP30BP,SEMA4D,SEPT4,SERBP1,SGK1,SGMS1,SGPL1,SIRT2,SIRT5,SIX1,SLC25A27,SLTM,SON,SOS1,SRPK2,STAMBP,STAR,STK17A,TAX1BP1,TBX3,TCF7,TCP1,TEX11,TGFB1,TGFBR1,THOC1,TIA1,TIAL1,TIGAR,TIMM50,TMBIM4,TMBIM6,TMEM214,TNFRSF10B,TNFRSF19,TNFRSF25,TNFSF12,TP63,TRADD,TRAF4,TRIM2,TRIM69,TRIO,TRPM7,TSC22D3,UBA52,UBE2B,UBE2Z,USP17L3,UTP11,VAV1,VEGFA,VIL1,WNT10B,WNT11,WRN,WWOX,XIAP,YBX3,YWHAQ,YWHAZ,ZC3H12A,ZC3H8,ZDHHC16,ZMAT4,ZNF385A 338.49 0.04261 0.408733922369765 GO:0009308 amine metabolic process biological_process 234 57 ABAT,ABHD3,ALDH7A1,AMD1,ATP2B4,AZIN2,BCHE,CLN3,DBI,DUOXA1,ENOPH1,ENPP2,FABP5,HDC,HPRT1,IDO1,LPCAT3,LPCAT4,LPIN1,MSRA,MTHFD1,MTHFD2L,MTRR,OAZ1,OAZ2,PAFAH1B1,PCYT1A,PDE1B,PLA2G10,PLA2G4B,PLA2G4C,PLA2G5,PLBD1,PON1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,SGMS1,SLC1A3,SLC44A4 45.94 0.04271 0.409275112244898 GO:0009206 purine ribonucleoside triphosphate biosy... biological_process 57 17 ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,GBAS,IMPDH1,MT-ATP6,NME4,NME5,NME6,NME7,NME9,SLC25A13,SURF1,TGFB1 11.19 0.04302 0.410987609359105 GO:0032204 regulation of telomere maintenance biological_process 57 17 ATR,ATRX,AURKB,CCT3,CCT7,HDAC8,HNRNPC,HNRNPU,MAP2K7,MAPKAPK5,NAT10,NEK7,PNKP,POT1,SMG6,TCP1,TNKS 11.19 0.04302 0.410987609359105 GO:0043666 regulation of phosphoprotein phosphatase... biological_process 57 17 ANKLE2,ARPP19,CALM1,EIF2AK2,HSP90B1,MASTL,PDGFRB,PPP1R12A,PPP1R2P3,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP6R3,RGN 11.19 0.04302 0.410987609359105 GO:0007126 meiotic nuclear division biological_process 175 44 ACTR2,AURKA,BOLL,CCNA1,DMC1,DPEP3,DUSP13,FANCA,FANCD2,FKBP6,FMN2,FZR1,HORMAD1,LFNG,LIF,MASTL,MKI67,MSH5,MSX2,NDC1,NPM2,PLCB1,PPP2R1A,RAD51C,RAD54B,RAD54L,RNF212,SGO1,SIRT2,SMC1A,SMC2,SMC4,SPDYA,STAG3,SYCP3,TERB2,TEX11,TEX14,TOP2B,TUBB8,TUBGCP5,UBE2B,WAPL,XRCC3 34.36 0.04318 0.411261034482759 GO:0051327 meiotic M phase biological_process 175 44 ACTR2,AURKA,BOLL,CCNA1,DMC1,DPEP3,DUSP13,FANCA,FANCD2,FKBP6,FMN2,FZR1,HORMAD1,LFNG,LIF,MASTL,MKI67,MSH5,MSX2,NDC1,NPM2,PLCB1,PPP2R1A,RAD51C,RAD54B,RAD54L,RNF212,SGO1,SIRT2,SMC1A,SMC2,SMC4,SPDYA,STAG3,SYCP3,TERB2,TEX11,TEX14,TOP2B,TUBB8,TUBGCP5,UBE2B,WAPL,XRCC3 34.36 0.04318 0.411261034482759 GO:0098762 meiotic cell cycle phase biological_process 175 44 ACTR2,AURKA,BOLL,CCNA1,DMC1,DPEP3,DUSP13,FANCA,FANCD2,FKBP6,FMN2,FZR1,HORMAD1,LFNG,LIF,MASTL,MKI67,MSH5,MSX2,NDC1,NPM2,PLCB1,PPP2R1A,RAD51C,RAD54B,RAD54L,RNF212,SGO1,SIRT2,SMC1A,SMC2,SMC4,SPDYA,STAG3,SYCP3,TERB2,TEX11,TEX14,TOP2B,TUBB8,TUBGCP5,UBE2B,WAPL,XRCC3 34.36 0.04318 0.411261034482759 GO:0050686 negative regulation of mRNA processing biological_process 29 10 C1QBP,CCNT1,CTR9,HNRNPA2B1,HNRNPK,RBMX,RNPS1,SAP18,SRSF7,TRA2B 5.69 0.04392 0.417462267206478 GO:1900449 regulation of glutamate receptor signali... biological_process 29 10 CNIH2,CRHBP,DAPK1,KLHL24,MEF2C,MINK1,NLGN3,OPRM1,PTK2B,RELN 5.69 0.04392 0.417462267206478 GO:0007098 centrosome cycle biological_process 74 21 AURKA,BRCA1,CENPJ,CEP135,CEP192,CEP63,CHMP3,CHMP5,CHORDC1,GEN1,KIAA0753,MDM1,NDE1,OFD1,PLK4,SASS6,TMEM67,TUBGCP5,USP33,XPO1,XRCC3 14.53 0.04436 0.421218159757331 GO:0030178 negative regulation of Wnt signaling pat... biological_process 198 49 AMER1,ANKRD6,CTNND1,CUL3,CXXC4,CYLD,DAB2IP,FZD6,GLI1,GPC3,GRB10,GSK3B,HDAC1,IGFBP2,JADE1,LIMD1,LRP6,LZTS2,NFATC1,NKD1,PRICKLE1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RNF43,SCYL2,SDHAF2,SIX3,UBA52,WNT11,WWOX,WWTR1 38.88 0.04445 0.421646414141414 GO:0051494 negative regulation of cytoskeleton orga... biological_process 113 30 ARHGAP6,ARHGEF2,BRCA1,C16orf45,CAPZA1,CARMIL2,CLASP1,CLASP2,EML2,FHOD3,FKBP4,GMFB,GMFG,GSN,HDAC6,KANK1,MAP6D1,MDM1,MID1IP1,MYOC,PFN2,PICK1,SPTB,SPTBN1,SPTBN4,TMEFF2,TMEM67,TRIOBP,TWF1,VIL1 22.19 0.04478 0.424348113017154 GO:0072666 establishment of protein localization to... biological_process 33 11 GCC2,GNPTG,HGS,NAGPA,SNX16,SORL1,TRAPPC8,VPS13A,VPS13C,VPS36,ZFYVE16 6.48 0.04502 0.426192358870968 GO:0032784 regulation of DNA-templated transcriptio... biological_process 45 14 BRD4,CTR9,DDX39B,EAPP,EZH2,HMGN1,LEO1,RECQL5,RNF8,SUPT4H1,TCEA2,TCEB1,THOC1,ZNF326 8.84 0.04523 0.426889376884422 GO:0034502 protein localization to chromosome biological_process 45 14 ATR,ATRX,AURKB,BUB1B,CENPA,ESR1,EZH2,H2AFY,HDAC8,MTBP,POT1,SPDL1,TNKS,WAPL 8.84 0.04523 0.426889376884422 GO:0035336 long-chain fatty-acyl-CoA metabolic proc... biological_process 45 14 ACACA,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,ELOVL6,ELOVL7,FAR1,HACD1,PPT2,SCD5,TECR 8.84 0.04523 0.426889376884422 GO:0006613 cotranslational protein targeting to mem... biological_process 100 27 RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS19,RPS2,RPS5,SEC63,SRP19,SSR1,SSR2,SSR3,TRAM1,UBA52 19.63 0.04536 0.427238901098901 GO:0006296 nucleotide-excision repair, DNA incision... biological_process 37 12 CUL4B,DDB1,GTF2H2,GTF2H3,GTF2H5,POLD3,POLD4,POLK,RFC2,RFC4,RPA3,UBA52 7.26 0.04551 0.427238901098901 GO:0086003 cardiac muscle cell contraction biological_process 37 12 ANK2,CACNA1C,CACNA2D1,FGF12,NEDD4L,NUP155,PDE4D,PKP2,RYR2,SCN3B,SRI,SUMO1 7.26 0.04551 0.427238901098901 GO:0009069 serine family amino acid metabolic proce... biological_process 41 13 AMT,DHFR,GART,GCAT,GCLC,GCLM,GCSH,GGT1,MTHFD1,MTRR,PSAT1,SHMT2,SLC25A32 8.05 0.04554 0.427238901098901 GO:0018196 peptidyl-asparagine modification biological_process 41 13 DAD1,DDOST,FUT8,MCFD2,OSTC,RPN2,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,UBE2G2,UGGT2 8.05 0.04554 0.427238901098901 GO:0035338 long-chain fatty-acyl-CoA biosynthetic p... biological_process 41 13 ACACA,ACOT8,ACOT9,ACSBG1,ACSF3,ACSL1,AGK,ELOVL6,ELOVL7,HACD1,PPT2,SCD5,TECR 8.05 0.04554 0.427238901098901 GO:2000146 negative regulation of cell motility biological_process 212 52 ABR,ADA,ADIPOR1,ADORA1,ANGPT2,ARHGAP4,ARID2,BCL2,BRAF,C16orf45,C5AR2,CERS2,CHRD,CTNNA1,CYP19A1,DAB2IP,DAG1,EVL,GCSAM,GSTP1,HOXA7,ITGB1BP1,KANK1,KRIT1,KRT16,MAP2K5,MARVELD3,MIA3,MMP28,MMRN2,NF1,NISCH,OSBPL8,PDCD10,PFN2,PIN1,PKP2,PLCB1,PODN,PTEN,PTPRK,RGN,ROBO1,SCAI,SEMA6D,SPINT2,SPOCK3,STRAP,TGFB1,THY1,TMEFF2,WNT11 41.62 0.04559 0.427281127744511 GO:0010769 regulation of cell morphogenesis involve... biological_process 337 79 ADIPOR1,ADNP,ARHGAP4,ARHGEF1,BRAF,C1QBP,CACNA1A,CAPRIN1,CDC42,CERS2,CHN1,CHRNA3,CLASP1,CLASP2,CUX1,CXCL12,DAB2IP,DAG1,DCC,DNM3,EPHA4,EPHB2,EZH2,GOLGA4,GORASP1,GSK3B,HDAC2,IFRD1,ITGB1BP1,KALRN,KANK1,KEL,KLK8,LIF,LIMK1,METRN,MYOC,NLGN3,NTRK2,NTRK3,OLFM1,PAFAH1B1,PAK3,PAX2,PHLDB1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PTEN,PTK2,RAPGEF2,RELN,RGMA,RNF6,ROBO1,RTN4,RUFY3,SDCBP,SDHAF2,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,SKIL,SMAD2,SMAD4,STK25,STRAP,TGFB1,TGFB1I1,TGFBR1,THY1,TRIOBP,ULK2,VEGFA,WWTR1 66.17 0.04593 0.429603892682927 GO:0010035 response to inorganic substance biological_process 450 103 ABAT,ADA,ADCY10,ADNP,AKR1B1,ALOX15,ANK3,ANXA7,APBB1,ATF2,ATIC,ATP2B4,ATP7B,ATRX,BCL2,BRAF,CACNA1H,CALM1,CARF,CASP8,CD14,CD9,CDH1,CPNE1,CPNE3,CPOX,CPS1,CRHBP,CRYAB,CYBB,DHFR,DTYMK,ECT2,EGFR,ENTPD6,EZH2,FAS,FBLN5,FUS,GART,GCLC,GGH,GIPR,GLRX2,GPX3,HDAC2,HDAC6,HMGCS1,HNRNPD,HSPD1,HVCN1,IGFBP2,IL18BP,IMPACT,JUND,KCNMA1,KMT2A,LIG4,MDM2,MEF2A,MEF2C,MNAT1,MT-CO1,NEDD4L,NFE2L2,NOS3,PAWR,PAX2,PDCD10,PDGFRB,PTEN,PTK2B,PXDN,QDPR,RASGRP2,RGN,RPLP0,RYR2,RYR3,SEC31A,SIPA1,SLC11A2,SLC25A13,SLC30A3,SLC30A5,SLC34A1,SOD3,SPAG16,STAR,STAT6,STK25,SYT1,SZT2,TESMIN,TF,TFR2,TIGAR,TNNT2,TRPA1,TRPC1,WNT10B,ZNF277,ZNF580 88.35 0.04625 0.429603892682927 GO:0043406 positive regulation of MAP kinase activi... biological_process 249 60 ADORA1,BIRC7,BRAF,CD74,CD81,CHRNA7,DAB2IP,DUSP9,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FGFR1,FRS2,GADD45G,HACD3,HTR2B,IGF1R,IL1B,IRAK1,KRAS,LAMTOR3,MADD,MAGED1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NOX4,NTRK3,PAK1,PAK3,PDCD10,PDE5A,PDGFRB,PIK3CB,PIK3R5,PTK2B,RAP1A,SASH1,SHC2,SPAG9,TAB2,TAB3,TGFA,TGFB1,TGFBR1,TLR9,UBA52,VEGFA 48.89 0.04656 0.429603892682927 GO:0051054 positive regulation of DNA metabolic pro... biological_process 185 46 AKT1,APBB1,ATR,ATRX,AURKB,BRCA1,CCT3,CCT7,CDC42,CTC1,DDX39B,DNA2,E2F7,EGFR,EYA3,EYA4,GLI1,GRHL2,IGF1R,INO80,MAP2K4,MAP2K7,MAPKAPK5,NEK7,NOX4,NPM2,NVL,PAK3,PDGFRB,PNKP,POT1,PTK2B,RFC2,RFC4,RIF1,RNF8,SLF1,STAT6,TCP1,TFRC,TGFB1,TIGAR,TNKS,UBE2B,WHSC1,WIZ 36.32 0.04673 0.429603892682927 GO:0031114 regulation of microtubule depolymerizati... biological_process 18 7 ARHGEF2,C16orf45,CLASP1,CLASP2,HDAC6,MAP6D1,MID1IP1 3.53 0.04683 0.429603892682927 GO:0033866 nucleoside bisphosphate biosynthetic pro... biological_process 18 7 ACACA,ACAT1,COASY,PANK1,PANK3,PANK4,PPCDC 3.53 0.04683 0.429603892682927 GO:0034030 ribonucleoside bisphosphate biosynthetic... biological_process 18 7 ACACA,ACAT1,COASY,PANK1,PANK3,PANK4,PPCDC 3.53 0.04683 0.429603892682927 GO:0034033 purine nucleoside bisphosphate biosynthe... biological_process 18 7 ACACA,ACAT1,COASY,PANK1,PANK3,PANK4,PPCDC 3.53 0.04683 0.429603892682927 GO:0034162 toll-like receptor 9 signaling pathway biological_process 18 7 HAVCR2,IRAK1,IRAK4,PIK3C3,TLR7,TLR9,UNC93B1 3.53 0.04683 0.429603892682927 GO:0034755 iron ion transmembrane transport biological_process 18 7 SLC11A2,STEAP1B,STEAP4,TF,TFR2,TFRC,TTYH1 3.53 0.04683 0.429603892682927 GO:0048679 regulation of axon regeneration biological_process 18 7 BRAF,CERS2,EPHA4,KLK8,NTRK3,PTEN,RGMA 3.53 0.04683 0.429603892682927 GO:0051000 positive regulation of nitric-oxide synt... biological_process 18 7 AKT1,CALM1,DHFR,FCER2,HTR2B,KRAS,PTK2B 3.53 0.04683 0.429603892682927 GO:0006228 UTP biosynthetic process biological_process 11 5 NME4,NME5,NME6,NME7,NME9 2.16 0.04689 0.429603892682927 GO:0009396 folic acid-containing compound biosynthe... biological_process 11 5 ATIC,DHFR,GART,MTHFD1,MTHFD2L 2.16 0.04689 0.429603892682927 GO:0010870 positive regulation of receptor biosynth... biological_process 11 5 HDAC1,HDAC2,HDAC6,HNRNPK,SCAP 2.16 0.04689 0.429603892682927 GO:0031581 hemidesmosome assembly biological_process 11 5 COL17A1,ITGA6,ITGB4,KRT5,LAMC2 2.16 0.04689 0.429603892682927 GO:0034244 negative regulation of transcription elo... biological_process 11 5 EAPP,EZH2,RECQL5,RNF8,SUPT4H1 2.16 0.04689 0.429603892682927 GO:0035246 peptidyl-arginine N-methylation biological_process 11 5 FBXO11,NDUFAF7,PRMT1,PRMT3,PRMT5 2.16 0.04689 0.429603892682927 GO:0045836 positive regulation of meiotic nuclear d... biological_process 11 5 MSX2,NPM2,PLCB1,SIRT2,UBE2B 2.16 0.04689 0.429603892682927 GO:0060211 regulation of nuclear-transcribed mRNA p... biological_process 11 5 AGO2,CNOT7,CPEB3,PABPC1,POLR2G 2.16 0.04689 0.429603892682927 GO:0060213 positive regulation of nuclear-transcrib... biological_process 11 5 AGO2,CNOT7,CPEB3,PABPC1,POLR2G 2.16 0.04689 0.429603892682927 GO:0060547 negative regulation of necrotic cell dea... biological_process 11 5 ARHGEF2,BIRC3,FADD,RBCK1,YBX3 2.16 0.04689 0.429603892682927 GO:0016049 cell growth biological_process 455 104 ADAM10,ADIPOR1,ADIPOR2,ADNP,AKT1,APBB1,APBB2,ARHGAP4,BAP1,BCAR1,BCL2,BLZF1,CACNA1A,CDC42,CDK11A,COBL,CRYAB,CSNK2A1,CSNK2A3,CXCL12,CYFIP1,DCBLD2,DCC,DDR1,DDX39B,EAF2,EGFR,EI24,EPB41L3,FAM107A,FBLN5,FGFR1OP,FHL1,GDF9,GNG4,GOLGA4,GSK3B,H2AFY,HDAC6,HYAL1,IFRD1,IGFBP2,INO80,IP6K2,ITGAV,JADE1,KMT2D,LAMTOR1,LGI1,LIMK1,MAP2K4,MAP2K5,MTOR,NLGN3,NME6,NOL8,NOP58,NRP2,NTRK3,OLFM1,PAFAH1B1,PIN1,PLXNA1,PLXNB1,PLXNC1,PLXND1,PPP2R1A,PRSS2,PTK2B,RAPH1,RASGRP2,RASGRP4,RBBP7,RNF6,ROS1,RPS6KA1,RTN4,RUFY3,SDCBP,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SGK1,SGMS1,SHTN1,SIPA1,SIRT6,SLC44A4,SMAD4,SMARCA2,SORBS2,ST7L,TFRC,TGFB1,TGFBR1,TMC8,TYMS,ULK2,USP9X,VEGFA,WISP2,WNT11 89.33 0.04689 0.429603892682927 GO:0006399 tRNA metabolic process biological_process 176 44 ADAT2,C14orf166,CARS,CDKAL1,DALRD3,DARS,DARS2,DDX1,ELAC2,EPRS,EXOSC8,FAM98B,FBL,GARS,HARS,LSM6,METTL1,MTO1,NARS,NAT10,PDCL3,QTRT1,RARS,RARS2,RPUSD1,RPUSD4,SSB,TARBP1,THUMPD1,THUMPD3,TPRKB,TRMT10A,TRMT10C,TRMT13,TRMT1L,TRMT6,TRUB1,TSEN15,TSEN2,TYW5,UBA5,WARS,WARS2,ZBTB8OS 34.56 0.04697 0.429681684518014 GO:0006915 apoptotic process biological_process 1703 361 ABR,ACIN1,ACTN1,ADA,ADCY10,ADCYAP1,ADNP,ADORA1,AHR,AIFM3,AIPL1,AKT1,AKTIP,ALDH1A3,AMBRA1,ANKLE2,ANO6,ANP32A,ANXA4,ANXA6,APBB1,APBB2,APH1A,APLP1,APPL1,ARHGAP4,ARHGEF12,ARHGEF16,ARHGEF2,ASIC2,ASNS,ATF2,ATF4,ATG3,AURKA,AURKB,BAG4,BAX,BBC3,BCAR1,BCL2,BCL2L14,BCL7C,BCLAF1,BIRC3,BIRC6,BIRC7,BLCAP,BLK,BNIP2,BOK,BRAF,BRCA1,BTK,BUB1B,C19orf68,C1D,C1QBP,C3orf38,C6orf120,CACNA1A,CAMK2A,CARD16,CASP4,CASP8,CD14,CD3G,CD44,CD74,CDC42,CDK11A,CDK5RAP3,CEACAM5,CFLAR,CHL1,CHMP3,CLDN7,CLEC5A,CLN3,CLU,COL4A3,CRYAB,CSE1L,CSF1R,CSNK2A1,CSNK2A2,CSRNP3,CTNNA1,CTNNBL1,CUL1,CUL3,CXCL12,CXCR2,CYLD,DAB2IP,DAD1,DAP3,DAPK1,DAPK3,DAPL1,DCC,DDB1,DDIAS,DDX20,DDX47,DHRS2,DIABLO,DICER1,DMPK,DNAJA1,DNAJC10,DNASE1,DNM1L,DPF1,DRAM2,DYRK2,EAF2,ECT2,EGFR,EI24,EIF2AK2,EN1,EPB41L3,ERN2,ERO1A,ESR1,ETV6,EVA1A,EYA3,EYA4,FADD,FAF1,FAS,FASTK,FGD3,FGD4,FGFR1,FIGNL1,FKBP8,FMN2,FNTA,FRS2,FXR1,G2E3,GABRA5,GADD45G,GCLC,GCLM,GDF9,GGCT,GLRX2,GLS2,GNGT1,GSK3B,GSN,GSTP1,HAP1,HDAC1,HDAC2,HIPK3,HMGA2,HNRNPK,HSP90B1,HSPD1,HTR2B,IDO1,IGF1R,IGF2R,IL1B,IL2RA,IP6K2,IRAK1,IRF5,ITGA6,ITGAV,ITGB3BP,ITM2C,ITPR1,JADE1,KALRN,KANK2,KCNB1,KCNMA1,KLHL20,KMT2A,KRAS,KRIT1,LCMT1,LCN2,LIG4,LIMS2,LITAF,LRP6,LTA,LTF,MADD,MAEA,MAGED1,MALT1,MAP1S,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAPK8,MCF2,MCF2L,MDM2,MDM4,MEF2A,MEF2C,MELK,MFF,MNAT1,MRPL41,MRPS30,MSX2,MTCH1,MTDH,MYO18A,NAA16,NAE1,NCOA1,NF1,NFE2L2,NFKBID,NISCH,NLRP12,NME4,NME6,NMT1,NOX4,NOX5,NR3C1,NSMAF,NTRK2,NTRK3,OGT,OPA1,PACS2,PAK1,PAK2,PAK3,PARP2,PAWR,PAX2,PAX3,PAX4,PAX7,PDCD10,PDCD2,PDCD5,PDCL3,PDE1B,PDGFRB,PHIP,PIAS1,PIGT,PIK3CA,PIN1,PLEKHG2,PLK3,POLB,POLR2G,POR,PPP2R1A,PRKCZ,PRLR,PSME3,PSMG2,PTEN,PTK2,PTK2B,PTPN6,PTRH2,RABEP1,RABGGTB,RALB,RAPGEF2,RAPSN,RASSF6,RBCK1,RBM25,RELT,RGN,RHBDD1,RHOT1,RNF216,RNPS1,ROBO1,RPS6KA1,RPS6KB1,RRP8,RTN3,RTN4,RYR2,SAP18,SAP30BP,SEMA4D,SEPT4,SERBP1,SGK1,SGMS1,SGPL1,SIRT2,SIRT5,SIX1,SLC25A27,SLTM,SON,SOS1,SRPK2,STAMBP,STAR,STK17A,TAX1BP1,TBX3,TCF7,TCP1,TEX11,TGFB1,TGFBR1,THOC1,TIA1,TIAL1,TIGAR,TIMM50,TMBIM4,TMBIM6,TMEM214,TNFRSF10B,TNFRSF19,TNFRSF25,TNFSF12,TP63,TRADD,TRAF4,TRIM2,TRIM69,TRIO,TSC22D3,UBA52,UBE2B,UBE2Z,USP17L3,UTP11,VAV1,VEGFA,VIL1,WNT10B,WNT11,WRN,WWOX,XIAP,YWHAQ,YWHAZ,ZC3H12A,ZC3H8,ZDHHC16,ZMAT4,ZNF385A 334.37 0.04699 0.429681684518014 GO:0036503 ERAD pathway biological_process 66 19 DNAJC10,EDEM3,HSP90B1,JKAMP,NPLOC4,POMT2,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,RNF121,SEC61B,TMEM67,UBE2G2,UBE2J2,UBE4A,UBXN4,UGGT2 12.96 0.04729 0.431584441205053 GO:1903363 negative regulation of cellular protein ... biological_process 66 19 ANXA2,BUB1B,CSNK2A1,CSNK2A2,DYNC1LI1,GEN1,KLHL40,LCMT1,N4BP1,PBK,PDCL3,PSMG2,SDCBP,TEX14,TLK2,TTK,WAC,XRCC3,ZNF207 12.96 0.04729 0.431584441205053 GO:0002429 immune response-activating cell surface ... biological_process 333 78 ABI1,ACTG1,ACTR2,ADA,ARPC1A,ARPC1B,BCAR1,BCL2,BLK,BTK,C5AR2,CACNB3,CD247,CD3G,CD79B,CDC42,CHUK,CLEC4E,CR1,CUL1,CYFIP1,DENND1B,ELF1,FBXW11,FYB,GCSAM,HLA-DPB1,KRAS,LAT,LIMK1,MALT1,MEF2C,MYO10,MYO1G,NCK1,NCKIPSD,NRAS,PAK1,PAK2,PAK3,PAWR,PDE4D,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTPN2,PTPN6,RBCK1,TAB2,TAB3,THY1,UBA52,UBE2V1,VAV1,ZAP70 65.38 0.04781 0.435906514563107 GO:0022603 regulation of anatomical structure morph... biological_process 960 209 ABR,ADA,ADIPOR1,ADNP,ALOX15,ANGPT2,ANGPTL3,ANKRD6,ANXA7,ARHGAP4,ARHGEF1,BAX,BCL2,BRAF,BRCA1,BRWD3,BTBD7,C1QBP,CACNA1A,CAPRIN1,CD44,CDC42,CDC42EP3,CELSR1,CELSR2,CERS2,CFLAR,CHAD,CHN1,CHRNA3,CHRNA7,CLASP1,CLASP2,CLTC,COL4A3,CSF1R,CSNK1G1,CUX1,CXCL12,CXCR2,CYBB,CYFIP1,DAAM1,DAB2IP,DAG1,DAPK3,DCC,DMRT2,DNM1L,DNM3,EHD2,ENPP2,EPB41L3,EPHA4,EPHB2,ESR1,ETV5,EZH2,FBLIM1,FES,FGD3,FGD4,FGD6,FGFR1,FMNL2,FOXJ1,FRS2,FZD6,GLI1,GNA12,GOLGA4,GORASP1,GPC3,GSK3B,GTF2I,HDAC2,HDAC7,HDAC9,HEXB,HYAL1,IFRD1,IL1B,IL4R,ITGA7,ITGB1BP1,KALRN,KANK1,KEL,KLK8,KRIT1,LARP4,LFNG,LGR4,LIF,LIMD1,LIMK1,LIMS2,MAGED1,MAP2K5,MARCH5,MEF2C,METRN,MFF,MKLN1,MKS1,MMRN2,MTDH,MYF6,MYH10,MYH9,MYO10,MYOC,NF1,NFE2L2,NKD1,NLGN3,NOS3,NTRK2,NTRK3,OLFM1,OMA1,OPA1,PAFAH1B1,PAK3,PAX2,PDCD10,PDCL3,PHIP,PHLDB1,PLXNA1,PLXNB1,PLXNC1,PLXND1,POR,PRICKLE1,PRPF40A,PRRX1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,RAP1A,RAPGEF2,RBPJ,RELN,RGMA,RNF6,RNH1,ROBO1,RTN4,RUFY3,RXRA,SASH1,SDCBP,SDHAF2,SEC24B,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SEPT7,SHTN1,SIX1,SKIL,SMAD2,SMAD4,SPRY1,STK25,STRAP,TAPT1,TGFB1,TGFB1I1,TGFBR1,THY1,TNFSF12,TRIOBP,UBA52,ULK2,UTS2,VASH2,VEGFA,VIL1,WARS,WNT10A,WNT11,WWTR1,ZC3H12A,ZMYM2,ZNF135 188.49 0.04815 0.43858064985451 GO:0006369 termination of RNA polymerase II transcr... biological_process 62 18 CHTOP,CSTF1,CSTF3,DDX39B,FIP1L1,NCBP2,NUDT21,PABPN1,POLDIP3,RNPS1,SNRPE,SNRPF,SRSF11,SRSF5,SRSF7,THOC1,THOC2,THOC7 12.17 0.04872 0.442057507246377 GO:0042273 ribosomal large subunit biogenesis biological_process 62 18 EIF6,MALSU1,MRPL1,NOP2,NSA2,RPF1,RPF2,RPL14,RPL26,RPL35A,RPL5,RPL6,RPL7L1,RSL24D1,SDAD1,SNU13,WDR12,YAE1D1 12.17 0.04872 0.442057507246377 GO:0042308 negative regulation of protein import in... biological_process 62 18 CYLD,DAB2IP,DYRK2,FAF1,FBXW11,GSK3B,LITAF,MTOR,NF1,NLRP12,PARP10,PDE2A,PPM1B,SRI,TBC1D10C,TRIP6,WWTR1,ZC3H12A 12.17 0.04872 0.442057507246377 GO:1904590 negative regulation of protein import biological_process 62 18 CYLD,DAB2IP,DYRK2,FAF1,FBXW11,GSK3B,LITAF,MTOR,NF1,NLRP12,PARP10,PDE2A,PPM1B,SRI,TBC1D10C,TRIP6,WWTR1,ZC3H12A 12.17 0.04872 0.442057507246377 GO:0031401 positive regulation of protein modificat... biological_process 1087 235 ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,AKTIP,ALOX15,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKLE2,ANKRD6,ANXA2,ARHGAP8,ARHGEF2,ARL2BP,ATP2B4,BAG4,BAX,BCL2,BIRC3,BIRC7,BRAF,BRCA1,BRD7,BUB1B,C5AR2,CACUL1,CALM1,CCDC88A,CCL25,CCNC,CCNL2,CCNT1,CCNT2,CD44,CD74,CD81,CDC23,CDC27,CDC42,CDC6,CDCA2,CDK5RAP3,CDON,CHFR,CHRNA3,CHRNA7,CHTOP,CLU,CNTN1,CSF1R,CTBP1,CTR9,CUL1,DAB2IP,DCUN1D4,DDR2,DOCK7,DUSP9,ECT2,EGF,EGFR,EIF2AK2,ENPP2,EPHA4,EZH2,FAM150A,FAM58A,FANCI,FAS,FBXO22,FGFR1,FNTA,FRS2,FZR1,GADD45G,GDF9,GPRC5B,GSK3B,HACD3,HAVCR2,HDAC1,HDAC2,HSPH1,HTR2B,IGF1R,IL15,IL1B,IRAK1,ITGA2,ITGB1BP1,KMT2A,KRAS,LAMTOR1,LAMTOR3,LAT,LIF,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK8IP3,MAPKAPK5,MEF2C,MINK1,MOB2,MST1R,MTF2,MTOR,MYB,NEK10,NIPBL,NOX1,NOX4,NTRK2,NTRK3,OGT,OPRK1,OPRM1,OSBPL8,PAK1,PAK2,PAK3,PAX7,PAXBP1,PDCD10,PDE5A,PDGFRB,PELI1,PFN2,PHF1,PIAS1,PIK3CA,PIK3CB,PIK3R5,PIN1,PLA2G5,PLCB1,PPP1R12A,PPP1R7,PPP2R3C,PRICKLE1,PRKAR2A,PRKCZ,PRLR,PRMT1,PRR5L,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,PTEN,PTK2,PTK2B,PTTG1IP,RALB,RAP1A,RAP1B,RAPGEF2,RBPMS,RCHY1,RELN,RELT,RGN,SASH1,SDCBP,SEMA4D,SEMA7A,SENP2,SEPT4,SHC2,SMAD4,SMYD3,SNX9,SORBS3,SPAG9,SPDYA,SPRTN,STAP2,STK25,TAB2,TAB3,TBK1,TELO2,TGFA,TGFB1,TGFBR1,TLR9,TNFRSF10B,TNFRSF19,TNFRSF25,TNK2,TOM1L1,TRAF4,TRIM5,TTK,UBA52,UBE2E1,UBE3A,VEGFA,WNT11,XIAP,ZC3H12A,ZP4 213.42 0.04908 0.44482730954677 GO:0007052 mitotic spindle organization biological_process 92 25 ANKRD53,ASUN,AURKA,AURKB,BIRC3,BIRC7,BORA,CHMP3,CHMP5,CLASP1,CLASP2,CLTC,DCTN2,FAM175B,KIF23,MAP9,OFD1,PRC1,RACGAP1,SMC1A,TNKS,TTK,TUBGCP5,XIAP,ZNF207 18.06 0.04912 0.44482730954677 GO:0045931 positive regulation of mitotic cell cycl... biological_process 114 30 ASNS,AURKA,BRD4,CDC6,CUL3,CUL4B,DYNC1LI1,EGF,EIF4E,GEN1,H2AFY,IL1B,MDM2,MTBP,NSMCE2,NUSAP1,PAFAH1B1,PBX1,PDGFRB,PHIP,PLCB1,PLRG1,RAD51C,RPS6KB1,SLF1,TGFA,TGFB1,UBE2E2,WNT10B,XRCC3 22.38 0.04973 0.449052336538462 GO:0048675 axon extension biological_process 114 30 ADNP,ARHGAP4,CXCL12,CYFIP1,GOLGA4,GSK3B,IFRD1,LIMK1,NLGN3,NRP2,NTRK3,OLFM1,PAFAH1B1,PLXNA1,PLXNB1,PLXNC1,PLXND1,RAPH1,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,ULK2,USP9X,VEGFA 22.38 0.04973 0.449052336538462 GO:1990138 neuron projection extension biological_process 114 30 ADNP,ARHGAP4,CXCL12,CYFIP1,GOLGA4,GSK3B,IFRD1,LIMK1,NLGN3,NRP2,NTRK3,OLFM1,PAFAH1B1,PLXNA1,PLXNB1,PLXNC1,PLXND1,RAPH1,RNF6,RTN4,RUFY3,SEMA4B,SEMA4D,SEMA6C,SEMA6D,SEMA7A,SHTN1,ULK2,USP9X,VEGFA 22.38 0.04973 0.449052336538462 GO:0044424 intracellular part cellular_component 13617 2950 AAAS,AAK1,AATK,ABAT,ABCA2,ABCA5,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABI3,ABLIM2,ABLIM3,ABR,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADCY4,ADD3,ADGB,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGBL1,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP14,AKAP3,AKAP7,AKIP1,AKNA,AKR1A1,AKR1B1,AKR1E2,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG13,ALG9,ALKBH2,ALOX15,ALPK1,AMBRA1,AMD1,AMDHD2,AMER1,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD26,ANKRD49,ANKRD53,ANKRD6,ANKS1B,ANLN,ANO2,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APLP1,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQP7,AQR,ARAP2,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARPP21,ARSA,ASAH1,ASB15,ASH1L,ASNS,ASPG,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATG3,ATG4B,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN10,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZI2,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLK,BLNK,BLZF1,BMP2K,BMS1,BNIP2,BOK,BOLL,BORA,BPIFB3,BPIFB4,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD2,BTBD7,BTBD9,BTF3,BTG3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C11orf21,C12orf4,C12orf65,C14orf159,C14orf166,C15orf39,C16orf45,C16orf62,C16orf89,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,C2orf88,C8orf44,C9orf142,CA1,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACNB3,CACNB4,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPN13,CAPN8,CAPRIN1,CAPS,CAPSL,CAPZA1,CARF,CARMIL2,CARS,CASC4,CASK,CASKIN1,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC6,CCDC61,CCDC78,CCDC88A,CCDC88C,CCDC89,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD247,CD2BP2,CD44,CD46,CD74,CD79B,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDH23,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CECR1,CELSR1,CELSR2,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP52,CFAP73,CFAP77,CFLAR,CHAC2,CHAD,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHMP3,CHMP5,CHMP6,CHN1,CHODL,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNGA1,CNIH1 2636.22 0 0 GO:0005622 intracellular cellular_component 13957 2995 AAAS,AAK1,AATK,ABAT,ABCA2,ABCA5,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABI3,ABLIM2,ABLIM3,ABR,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADCY4,ADCYAP1,ADD3,ADGB,ADK,ADNP,ADORA1,ADPGK,ADPRHL1,AEBP1,AFF3,AGBL1,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP14,AKAP3,AKAP7,AKIP1,AKNA,AKR1A1,AKR1B1,AKR1E2,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG13,ALG9,ALKBH2,ALOX15,ALPK1,AMBRA1,AMD1,AMDHD2,AMER1,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD26,ANKRD49,ANKRD53,ANKRD6,ANKS1B,ANLN,ANO10,ANO2,ANO6,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APLP1,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQP7,AQR,ARAP2,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL5C,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARPP21,ARSA,ASAH1,ASB15,ASH1L,ASNS,ASPG,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATG3,ATG4B,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN10,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZI2,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLK,BLNK,BLZF1,BMP2K,BMS1,BNIP2,BOK,BOLL,BORA,BPIFB3,BPIFB4,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD2,BTBD7,BTBD9,BTF3,BTG3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C11orf21,C12orf4,C12orf65,C14orf159,C14orf166,C15orf39,C16orf45,C16orf62,C16orf89,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,C2orf88,C8orf44,C9orf142,CA1,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACNB3,CACNB4,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPN13,CAPN8,CAPRIN1,CAPS,CAPSL,CAPZA1,CARF,CARMIL2,CARS,CASC4,CASK,CASKIN1,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC6,CCDC61,CCDC78,CCDC88A,CCDC88C,CCDC89,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD247,CD2BP2,CD44,CD46,CD74,CD79B,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDH23,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CECR1,CELSR1,CELSR2,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP52,CFAP73,CFAP77,CFLAR,CHAC2,CHAD,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHMP3,CHMP5,CHMP6,CHN1,CHODL,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CMC2 2702.04 0 0 GO:0044428 nuclear part cellular_component 3909 1079 AAAS,ABCB8,ABTB1,ACACA,ACADVL,ACIN1,ACTL6A,ADAT2,ADD3,ADK,AFF3,AGFG1,AGO1,AGO2,AHCTF1,AHR,AIP,AK6,AKIP1,AKR1B1,AKT1,AKTIP,ALKBH2,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,ANXA4,ANXA7,AP5Z1,APBB1,APEX2,APOBEC3F,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARMC4,ARPP19,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATOH8,ATP11B,ATP23,ATP2A3,ATP5H,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BAHCC1,BANP,BAP1,BAX,BAZ1A,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCL2,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BNIP2,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,BTN3A3,BUB1B,BUD31,C14orf166,C1D,C1QBP,C2orf88,C8orf44,C9orf142,CABIN1,CACUL1,CADPS2,CALM1,CAMK2A,CAMK2G,CAND1,CARF,CASK,CASP8,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK5RAP3,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP170,CEP350,CEP57,CEP70,CERS2,CFAP20,CHD2,CHD3,CHD6,CHD7,CHFR,CHRAC1,CHTOP,CHUK,CIART,CIR1,CLIP1,CLK2,CNDP2,CNOT7,COASY,COG5,COPS2,COPS3,CPEB1,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRBN,CRCP,CREM,CRNKL1,CRYAB,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,CYBB,DAG1,DAP3,DAPK3,DBF4,DCAF11,DCAF13,DCAF17,DCTN1,DDB1,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEPDC1,DGKZ,DHCR7,DHFR,DHRS2,DHX15,DHX40,DICER1,DIMT1,DLD,DMC1,DMPK,DMTF1,DNA2,DNAJC1,DNAJC8,DNASE1,DNTTIP2,DOCK7,DOT1L,DPF1,DPH3,DPP3,DPPA4,DPY19L1,DPY19L3,DPY19L4,DQX1,DR1,DROSHA,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EEF1D,EGFR,EHMT1,EHMT2,EI24,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EPN3,ERCC6L,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETNK1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAF1,FAM110C,FAM118B,FAM156A,FAM175B,FAM193B,FAM200B,FAM206A,FAM208B,FAM21A,FAM222B,FAM64A,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FBL,FBXL4,FBXO11,FIGNL1,FIP1L1,FKBP4,FKBP6,FLII,FMN2,FNBP4,FUBP1,FUS,FXR1,FZR1,G2E3,GABPB1,GARS,GATAD2A,GATAD2B,GCAT,GEN1,GGA1,GLI1,GLRX2,GNL2,GOLGA4,GPATCH1,GPBP1,GPRC5B,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GTPBP10,GZF1,H2AFV,H2AFY,HACD3,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HEYL,HIPK3,HIST1H2BN,HIST2H2AC,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HORMAD1,HOXA10,HOXA9,HOXD11,HS6ST2,HSF4,HSPA8,HSPD1,HSPH1,HUS1,HYPK,ICE1,ICE2,IGF2R,IL15,IMPDH1,INCENP,INO80,INO80C,INO80E,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO11,IPO8,IPO9,IQCB1,IRF2,ITGB3BP,ITPR1,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KATNBL1,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRI1,KRR1,L3MBTL1,LARP7,LAT,LBR,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMNTD1,LMO2,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTV1,LUC7L,LUC7L3,MAEA,MAFK,MAGI1,MAGOHB,MALT1,MAP1S,MAP2,MAP2K3,MAP3K2,MAPK4,MAPK8,MAPKAPK5,MASTL,MAU2,MBD3,MBNL1,MCM2,MCM8,MCMBP,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,METTL1,METTL14 756.77 0 0 GO:0044422 organelle part cellular_component 8314 1985 AAAS,ABAT,ABCA2,ABCA5,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABLIM3,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACIN1,ACOT8,ACOT9,ACOX3,ACOXL,ACSF3,ACSL1,ACTG1,ACTL6A,ACTN1,ACTR2,ACTR3C,ADA,ADAM10,ADAMTSL1,ADAT2,ADD3,ADK,ADORA1,AFF3,AGFG1,AGK,AGO1,AGO2,AHCTF1,AHNAK,AHR,AIFM3,AIP,AK2,AK6,AKAP1,AKAP11,AKAP3,AKIP1,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH3A2,ALDH7A1,ALG13,ALG9,ALKBH2,AMBRA1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANK2,ANK3,ANKLE2,ANKRD11,ANKRD12,ANKRD26,ANKRD53,ANKS1B,ANLN,ANO2,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APEX2,APH1A,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP4,ARHGAP6,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC4,ARPC1A,ARPC1B,ARPP19,ARSA,ASAH1,ASH1L,ASPSCR1,ASUN,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATL2,ATOH8,ATP11B,ATP11C,ATP23,ATP2A3,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AZIN2,B3GALNT2,BAHCC1,BANP,BAP1,BAX,BAZ1A,BAZ2A,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BPTF,BRCA1,BRD4,BRD7,BRIP1,BSN,BTBD10,BTN3A3,BUB1B,BUD31,C12orf65,C14orf166,C1D,C1QBP,C2CD5,C2orf88,C8orf44,C9orf142,CABIN1,CABYR,CACNA1C,CACNA1S,CACUL1,CADPS2,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAND1,CAPZA1,CARF,CASK,CASP4,CASP8,CATSPER4,CBX5,CCDC110,CCDC114,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC61,CCDC78,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD2BP2,CD46,CD74,CD79B,CD9,CDC14B,CDC23,CDC27,CDC42,CDC6,CDCA2,CDH1,CDH23,CDHR1,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDS2,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP126,CFAP20,CFAP221,CFAP46,CHCHD3,CHCHD7,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHMP3,CHMP5,CHMP6,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CKAP4,CKMT2,CLASP1,CLASP2,CLCN3,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CNDP2,CNGA1,CNIH1,CNIH2,CNOT7,CNST,COA1,COASY,COBL,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPA,COPB1,COPS2,COPS3,COQ4,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPEB1,CPOX,CPS1,CPSF3L,CPSF6,CPT1C,CPT2,CRACR2A,CRBN,CRCP,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK2A1,CSNK2A2,CSPP1,CSTF1,CSTF3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,CYBB,CYLD,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAAM1,DAD1,DAG1,DAP3,DAPK3,DARS2,DBF4,DBT,DCAF11,DCAF13,DCAF17,DCTN1,DCTN2,DCTN4,DCTN6,DCXR,DDB1,DDOST,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEGS1,DENND4C,DEPDC1,DES,DGKZ,DHCR7,DHFR,DHRS2,DHX15,DHX40,DIABLO,DICER1,DIMT1,DLAT,DLD,DLG2,DLG3,DLGAP1,DMBT1,DMC1,DMPK,DMTF1,DMXL2,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNAJB11,DNAJB13,DNAJB14,DNAJC1,DNAJC10,DNAJC13,DNAJC8,DNALI1,DNASE1,DNM1L,DNM3,DNTTIP2,DOCK4,DOCK7,DOT1L,DPAGT1,DPF1,DPH3,DPP3,DPPA4,DPY19L1,DPY19L3,DPY19L4 1609.57 0 0 GO:0044446 intracellular organelle part cellular_component 8188 1955 AAAS,ABAT,ABCA2,ABCA5,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABLIM3,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACIN1,ACOT8,ACOT9,ACOX3,ACOXL,ACSF3,ACSL1,ACTG1,ACTL6A,ACTN1,ACTR2,ACTR3C,ADA,ADAM10,ADAMTSL1,ADAT2,ADD3,ADK,ADORA1,AFF3,AGFG1,AGK,AGO1,AGO2,AHCTF1,AHNAK,AHR,AIFM3,AIP,AK2,AK6,AKAP1,AKAP11,AKAP3,AKIP1,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH3A2,ALDH7A1,ALG13,ALG9,ALKBH2,AMBRA1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKLE2,ANKRD11,ANKRD12,ANKRD26,ANKRD53,ANKS1B,ANLN,ANO2,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APEX2,APH1A,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP4,ARHGAP6,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC4,ARPC1A,ARPC1B,ARPP19,ARSA,ASAH1,ASH1L,ASPSCR1,ASUN,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATL2,ATOH8,ATP11B,ATP11C,ATP23,ATP2A3,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AZIN2,B3GALNT2,BAHCC1,BANP,BAP1,BAX,BAZ1A,BAZ2A,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BPTF,BRCA1,BRD4,BRD7,BRIP1,BSN,BTBD10,BTN3A3,BUB1B,BUD31,C12orf65,C14orf166,C1D,C1QBP,C2CD5,C2orf88,C8orf44,C9orf142,CABIN1,CABYR,CACNA1C,CACUL1,CADPS2,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAND1,CAPZA1,CARF,CASK,CASP4,CASP8,CATSPER4,CBX5,CCDC110,CCDC114,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC61,CCDC78,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD2BP2,CD46,CD74,CD79B,CD9,CDC14B,CDC23,CDC27,CDC42,CDC6,CDCA2,CDH1,CDHR1,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDS2,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP126,CFAP20,CHCHD3,CHCHD7,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHMP3,CHMP5,CHMP6,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIR1,CKAP4,CKMT2,CLASP1,CLASP2,CLCN3,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CNDP2,CNGA1,CNIH1,CNIH2,CNOT7,CNST,COA1,COASY,COBL,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPA,COPB1,COPS2,COPS3,COQ4,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPEB1,CPOX,CPS1,CPSF3L,CPSF6,CPT1C,CPT2,CRACR2A,CRBN,CRCP,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK2A1,CSNK2A2,CSPP1,CSTF1,CSTF3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,CYBB,CYLD,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAAM1,DAD1,DAG1,DAP3,DAPK3,DARS2,DBF4,DBT,DCAF11,DCAF13,DCAF17,DCTN1,DCTN2,DCTN4,DCTN6,DCXR,DDB1,DDOST,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEGS1,DENND4C,DEPDC1,DES,DGKZ,DHCR7,DHFR,DHRS2,DHX15,DHX40,DIABLO,DICER1,DIMT1,DLAT,DLD,DLG2,DLG3,DLGAP1,DMBT1,DMC1,DMPK,DMTF1,DMXL2,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNAJB11,DNAJB14,DNAJC1,DNAJC10,DNAJC13,DNAJC8,DNALI1,DNASE1,DNM1L,DNM3,DNTTIP2,DOCK7,DOT1L,DPAGT1,DPF1,DPH3,DPP3,DPPA4,DPY19L1,DPY19L3,DPY19L4,DQX1,DR1,DRAM2,DROSHA,DTYMK,DUOXA1,DUSP16,DYNC1I2,DYNC1LI1 1585.18 0 0 GO:0043229 intracellular organelle cellular_component 11958 2637 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABLIM2,ABLIM3,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADD3,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKNA,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG13,ALG9,ALKBH2,ALOX15,AMBRA1,AMDHD2,AMER1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD26,ANKRD49,ANKRD53,ANKRD6,ANKS1B,ANLN,ANO2,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP4,ARHGAP5,ARHGAP6,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARSA,ASAH1,ASB15,ASH1L,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD2,BTBD7,BTF3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C12orf65,C14orf159,C14orf166,C16orf45,C16orf62,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,C2orf88,C8orf44,C9orf142,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPN8,CAPRIN1,CAPS,CAPZA1,CARF,CARMIL2,CASC4,CASK,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC6,CCDC61,CCDC78,CCDC88A,CCDC89,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD2BP2,CD44,CD46,CD74,CD79B,CD9,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH23,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP73,CFAP77,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHMP3,CHMP5,CHMP6,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNGA1,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,COA1,COASY,COBL,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COMMD4,COPA,COPB1,COPS2,COPS3,COQ4,CORO2B,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPA2,CPEB1,CPEB3,CPLX2,CPNE1,CPNE3,CPOX,CPQ,CPS1,CPSF3L,CPSF6,CPT1C,CPT2,CRACR2A,CRAMP1,CRBN,CRCP,CREB5,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK1G1,CSNK2A1,CSNK2A2,CSPP1,CSRNP3 2315.04 0 0 GO:0031981 nuclear lumen cellular_component 3540 969 AAAS,ABCB8,ABTB1,ACACA,ACADVL,ACIN1,ACTL6A,ADAT2,ADD3,ADK,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AK6,AKIP1,AKR1B1,AKT1,AKTIP,ALKBH2,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,AP5Z1,APBB1,APEX2,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARMC4,ARPP19,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATOH8,ATP5H,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BANP,BAP1,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,BTN3A3,BUB1B,BUD31,C14orf166,C1D,C1QBP,C2orf88,C8orf44,CABIN1,CADPS2,CALM1,CAMK2A,CAMK2G,CAND1,CARF,CASK,CASP8,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK5RAP3,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP350,CEP57,CEP70,CFAP20,CHD2,CHD3,CHD6,CHD7,CHFR,CHRAC1,CHTOP,CHUK,CIART,CIR1,CLK2,CNDP2,CNOT7,COASY,COG5,COPS2,COPS3,CPEB1,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRBN,CRCP,CREM,CRNKL1,CRYAB,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTC1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,DAG1,DAP3,DAPK3,DBF4,DCAF11,DCAF13,DCAF17,DDB1,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEPDC1,DGKZ,DHFR,DHX15,DHX40,DIMT1,DLD,DMC1,DMTF1,DNA2,DNAJC8,DNTTIP2,DOT1L,DPH3,DPP3,DPPA4,DR1,DROSHA,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EEF1D,EHMT1,EHMT2,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EPN3,ERCC6L,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETNK1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAM110C,FAM118B,FAM193B,FAM200B,FAM206A,FAM208B,FAM21A,FAM222B,FAM64A,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FBL,FBXL4,FBXO11,FIGNL1,FIP1L1,FKBP4,FKBP6,FLII,FMN2,FNBP4,FUBP1,FUS,FXR1,FZR1,G2E3,GABPB1,GARS,GATAD2A,GATAD2B,GCAT,GEN1,GGA1,GLI1,GLRX2,GNL2,GOLGA4,GPBP1,GPRC5B,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GTPBP10,GZF1,H2AFV,H2AFY,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HEYL,HIPK3,HIST1H2BN,HIST2H2AC,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HORMAD1,HOXA10,HOXA9,HOXD11,HS6ST2,HSF4,HSPA8,HSPH1,HUS1,HYPK,ICE1,ICE2,IL15,IMPDH1,INCENP,INO80,INO80C,INO80E,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO8,IQCB1,IRF2,ITGB3BP,ITPR1,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KATNBL1,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRI1,KRR1,L3MBTL1,LARP7,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMO2,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTV1,LUC7L3,MAEA,MAFK,MAGI1,MALT1,MAP1S,MAP2,MAP2K3,MAP3K2,MAPK4,MAPK8,MAPKAPK5,MASTL,MAU2,MBD3,MBNL1,MCM2,MCM8,MCMBP,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,METTL1,METTL14,MGA,MIDN,MIER1,MIS18BP1,MKI67,MKNK1,MMS22L,MNAT1,MOB2,MORF4L1,MPHOSPH10,MPPE1,MSH5,MSRA,MTA1,MTA3,MTDH,MTF2,MTIF2,MTOR,MTRR,MUTYH,MYB,MYF6,MYO10,MYO16,MYO18A,N4BP1,NAA10,NAA16,NAA25,NARF,NASP,NAT10,NCBP2,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NDRG2,NDUFA9,NDUFB4,NDUFB5,NEDD4L,NEK11,NEK7,NEPRO,NF1,NFATC1,NFU1 685.34 0 0 GO:0043226 organelle cellular_component 12834 2778 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABLIM2,ABLIM3,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTL8,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADD3,ADGRG2,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP12,AKAP3,AKAP7,AKIP1,AKNA,AKR1A1,AKR1B1,AKR1E2,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG13,ALG9,ALKBH2,ALOX15,ALPL,AMBRA1,AMDHD2,AMER1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK2,ANK3,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD26,ANKRD49,ANKRD53,ANKRD6,ANKS1B,ANLN,ANO2,ANO6,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP4,ARHGAP5,ARHGAP6,ARHGEF12,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARSA,ART3,ASAH1,ASB15,ASH1L,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BOLA2,BPIFB1,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BROX,BRWD3,BSN,BTBD10,BTBD2,BTBD7,BTF3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C12orf65,C14orf159,C14orf166,C16orf45,C16orf62,C16orf89,C17orf80,C19orf68,C1D,C1QBP,C1QTNF5,C1RL,C1S,C2,C2CD5,C2orf88,C4A,C4B,C6orf120,C8orf44,C9orf142,CA1,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPN8,CAPRIN1,CAPS,CAPZA1,CARF,CARMIL2,CASC4,CASK,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC14,CCDC146,CCDC174,CCDC181,CCDC59,CCDC6,CCDC61,CCDC78,CCDC88A,CCDC89,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD22,CD2BP2,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDH23,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CEACAM5,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP73,CFAP77,CFHR3,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHL1,CHMP3,CHMP5,CHMP6,CHRAC1,CHRNA3,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLDN11,CLEC18A,CLEC2D,CLIP1,CLIP2,CLK2,CLN3,CLN8,CLRN3,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNGA1,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,CNTN1,COA1,COASY,COBL,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COMMD4,COPA,COPB1,COPS2,COPS3,COQ4,CORO2B,CORO7,COX17,COX20,COX5A,COX6A1 2484.63 0 0 GO:0043231 intracellular membrane-bounded organelle cellular_component 11007 2436 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTN1,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADD3,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP3,AKAP7,AKIP1,AKNA,AKR1B1,AKT1,AKTIP,ALDH18A1,ALDH1L1,ALDH3A2,ALDH7A1,ALG13,ALG9,ALKBH2,AMBRA1,AMDHD2,AMER1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK3,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD49,ANKRD6,ANKS1B,ANLN,ANO2,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP4,ARHGAP5,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPP19,ARSA,ASAH1,ASB15,ASH1L,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCLAF1,BET1,BICD1,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BRWD3,BSN,BTBD10,BTBD7,BTF3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C12orf65,C14orf159,C14orf166,C16orf62,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,C2orf88,C8orf44,C9orf142,CABIN1,CABYR,CACNA1A,CACNA2D1,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMTA1,CAND1,CAPN8,CAPS,CARF,CARMIL2,CASC4,CASK,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC174,CCDC181,CCDC59,CCDC78,CCDC88A,CCDC89,CCDC90B,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD2BP2,CD44,CD46,CD74,CD79B,CD9,CDC14B,CDC23,CDC27,CDC42,CDC6,CDCA2,CDH1,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP170,CEP290,CEP350,CEP57,CEP70,CEP89,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP73,CFAP77,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHMP3,CHMP5,CHMP6,CHRAC1,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLK2,CLN3,CLN8,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNGA1,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,COA1,COASY,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COMMD4,COPA,COPB1,COPS2,COPS3,COQ4,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPA2,CPEB1,CPEB3,CPLX2,CPNE1,CPNE3,CPOX,CPQ,CPS1,CPSF3L,CPSF6,CPT1C,CPT2,CRACR2A,CRAMP1,CRBN,CRCP,CREB5,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK1G1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1,CSTF3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNA1,CTNNBL1,CTNND1,CTR9,CTTNBP2,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,CXCR2,CXorf23,CYBB,CYLD,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAAM1,DAB2IP,DAD1,DAG1,DAP3,DAPK3,DARS2,DBF4,DBI,DBT,DCAF11,DCAF13 2130.93 0 0 GO:0005654 nucleoplasm cellular_component 2992 824 AAAS,ACIN1,ACTL6A,ADAT2,ADD3,ADK,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AK6,AKIP1,AKR1B1,AKT1,ALKBH2,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,AP5Z1,APBB1,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARMC4,ARPP19,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATG16L2,ATOH8,ATP5H,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BANP,BAP1,BAZ2A,BBX,BCAS2,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,C14orf166,C1D,C2orf88,C8orf44,CABIN1,CADPS2,CALM1,CAMK2A,CAMK2G,CAND1,CARF,CASP8,CBX5,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP350,CEP57,CEP70,CFAP20,CHD2,CHD3,CHD6,CHFR,CHTOP,CHUK,CIART,CIR1,CLK2,CNDP2,CNOT7,COASY,COG5,COPS2,COPS3,CPEB1,CPSF3L,CPSF6,CPT2,CRCP,CREM,CRNKL1,CRYAB,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,DAG1,DAP3,DAPK3,DBF4,DCAF11,DCAF13,DDB1,DDX1,DDX20,DDX23,DDX39B,DDX42,DDX47,DEPDC1,DGKZ,DHFR,DIMT1,DLD,DMC1,DMTF1,DNA2,DNAJC8,DOT1L,DPH3,DPP3,DPPA4,DR1,DROSHA,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EHMT1,EHMT2,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EPN3,ERCC6L,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETNK1,ETV5,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAM110C,FAM118B,FAM193B,FAM200B,FAM206A,FAM208B,FAM222B,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FBL,FBXL4,FIP1L1,FKBP4,FLII,FNBP4,FUBP1,FUS,FZR1,GABPB1,GARS,GATAD2A,GATAD2B,GCAT,GEN1,GGA1,GLI1,GLRX2,GOLGA4,GPBP1,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GZF1,H2AFY,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HEYL,HIPK3,HIST1H2BN,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HOXA10,HOXA9,HOXD11,HS6ST2,HSF4,HSPA8,HSPH1,HUS1,HYPK,ICE1,ICE2,IL15,IMPDH1,INCENP,INO80C,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO8,IQCB1,IRF2,ITGB3BP,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRR1,L3MBTL1,LARP7,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMO2,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTV1,LUC7L3,MAFK,MAGI1,MAP2K3,MAP3K2,MAPK4,MAPK8,MAPKAPK5,MASTL,MAU2,MBD3,MBNL1,MCM2,MCM8,MCMBP,MDM2,MDM4,MEAF6,MED12L,MED13,MED13L,MED14,MED16,MED21,MED23,MED24,MED30,MED31,MEF2A,MEF2C,METTL1,METTL14,MGA,MIER1,MIS18BP1,MKNK1,MMS22L,MNAT1,MORF4L1,MPHOSPH10,MPPE1,MSRA,MTA1,MTA3,MTDH,MTF2,MTIF2,MTOR,MTRR,MUTYH,MYF6,MYO16,MYO18A,N4BP1,NAA16,NAA25,NASP,NAT10,NCBP2,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NDRG2,NDUFA9,NDUFB4,NDUFB5,NEDD4L,NEK11,NEK7,NFATC1,NFU1,NFYA,NIPBL,NKRF,NMI,NOC3L,NOP10,NOP56,NOP58,NPAS3,NPLOC4,NR2C1,NR3C1,NR3C2,NSMCE1,NSMCE2,NSMCE4A,NUDT21,NUP107,NUP205,NUP35,NUP37,NUP50,NUP98,NUPL2,NVL,NXF3,OGT,ONECUT2,OPA1,ORC4,OSBPL1A,PABPN1,PAK2,PAPOLG,PARP10,PARP2,PARPBP,PAX3,PAX4,PBX1,PCBD1,PCBP2,PDHB,PDIK1L,PDS5B,PDXK,PEAK1,PEX3,PFDN2,PHC3,PHF1,PHF12,PHF20,PHF21A,PHF6,PIAS1,PIN1,PIP5K1A,PKP2,PLA2G4C,PLCB1,PLK3,PLRG1,PMS2,PNISR,PNKP 579.24 0 0 GO:0070013 intracellular organelle lumen cellular_component 4249 1097 AAAS,ABAT,ABCB8,ABCE1,ABHD10,ABTB1,ACACA,ACAD8,ACADVL,ACAT1,ACIN1,ACOT8,ACOT9,ACOX3,ACOXL,ACSF3,ACTL6A,ADAMTSL1,ADAT2,ADD3,ADK,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AK6,AKIP1,AKR1B1,AKT1,AKTIP,ALDH7A1,ALKBH2,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,AP5Z1,APBB1,APEX2,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARL2BP,ARMC4,ARPP19,ARSA,ASAH1,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATOH8,ATP5B,ATP5E,ATP5H,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BANP,BAP1,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCHE,BCKDHB,BCKDK,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,BTN3A3,BUB1B,BUD31,C12orf65,C14orf166,C1D,C1QBP,C2orf88,C8orf44,CABIN1,CADPS2,CALM1,CALU,CAMK2A,CAMK2G,CAND1,CARF,CASK,CASP8,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD74,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK5RAP3,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP350,CEP57,CEP70,CES1,CFAP20,CHD2,CHD3,CHD6,CHD7,CHFR,CHRAC1,CHTOP,CHUK,CIART,CIR1,CLK2,CNDP2,CNOT7,COASY,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPS2,COPS3,CPEB1,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRBN,CRCP,CREM,CRNKL1,CROT,CRYAB,CRYM,CS,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTC1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,DAG1,DAP3,DAPK3,DARS2,DBF4,DBT,DCAF11,DCAF13,DCAF17,DDB1,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEPDC1,DGKZ,DHFR,DHRS2,DHX15,DHX40,DIMT1,DLAT,DLD,DMC1,DMTF1,DNA2,DNAJB11,DNAJC10,DNAJC8,DNTTIP2,DOT1L,DPH3,DPP3,DPPA4,DR1,DROSHA,DTYMK,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EDEM3,EEF1D,EHMT1,EHMT2,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EOGT,EPN3,ERAP2,ERCC6L,ERLEC1,ERO1A,ESD,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETFA,ETNK1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAM110C,FAM118B,FAM193B,FAM200B,FAM206A,FAM208B,FAM21A,FAM222B,FAM64A,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FAR1,FASTK,FBL,FBXL4,FBXO11,FDXR,FIGNL1,FIP1L1,FKBP4,FKBP6,FLAD1,FLII,FMN2,FNBP4,FUBP1,FUS,FXR1,FZR1,G2E3,GABPB1,GALC,GARS,GATAD2A,GATAD2B,GCAT,GCSH,GEN1,GGA1,GIF,GLA,GLI1,GLRX2,GLS,GLS2,GNL2,GNPAT,GOLGA4,GPBP1,GPC1,GPC3,GPRC5B,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GTPBP10,GZF1,H2AFV,H2AFY,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HEXB,HEYL,HIPK3,HIST1H2BN,HIST2H2AC,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HORMAD1,HOXA10,HOXA9,HOXD11,HS6ST2,HSD17B4,HSF4,HSP90B1,HSPA8,HSPD1,HSPH1,HUS1,HYAL1,HYPK,ICE1,ICE2,IL15,IMPDH1,INCENP,INO80,INO80C,INO80E,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO8,IQCB1,IRF2,ITGB3BP,ITPR1,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KATNBL1,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRI1,KRR1,L3MBTL1,LAMP2,LARP7,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMO2,LNPEP,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTV1,LUC7L3,MAEA,MAFK,MAGI1,MALSU1,MALT1,MAP1S,MAP2,MAP2K3,MAP3K2,MAPK4,MAPK8,MAPKAPK5,MASTL,MAU2,MBD3,MBNL1,MCM2,MCM8 822.6 0 0 GO:0031974 membrane-enclosed lumen cellular_component 4376 1121 AAAS,ABAT,ABCB8,ABCE1,ABHD10,ABTB1,ACACA,ACAD8,ACADVL,ACAT1,ACIN1,ACOT8,ACOT9,ACOX3,ACOXL,ACSF3,ACTL6A,ACTN1,ADA,ADAMTSL1,ADAT2,ADD3,ADK,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AK2,AK6,AKIP1,AKR1B1,AKT1,AKTIP,ALDH7A1,ALKBH2,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,AP5Z1,APBB1,APEX2,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARL2BP,ARMC4,ARPP19,ARSA,ASAH1,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATOH8,ATP5B,ATP5E,ATP5H,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BANP,BAP1,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCHE,BCKDHB,BCKDK,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,BTN3A3,BUB1B,BUD31,C12orf65,C14orf166,C1D,C1QBP,C2orf88,C8orf44,CABIN1,CADPS2,CALM1,CALU,CAMK2A,CAMK2G,CAND1,CARF,CASK,CASP8,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD74,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK5RAP3,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP350,CEP57,CEP70,CEP89,CES1,CFAP20,CHCHD7,CHD2,CHD3,CHD6,CHD7,CHFR,CHRAC1,CHTOP,CHUK,CIART,CIR1,CLK2,CLU,CNDP2,CNOT7,COASY,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPS2,COPS3,COX17,COX6B2,CPEB1,CPOX,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRBN,CRCP,CREM,CRNKL1,CROT,CRYAB,CRYM,CS,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTC1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,DAG1,DAP3,DAPK3,DARS2,DBF4,DBT,DCAF11,DCAF13,DCAF17,DDB1,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEPDC1,DGKZ,DHFR,DHRS2,DHX15,DHX40,DIABLO,DIMT1,DLAT,DLD,DMC1,DMTF1,DNA2,DNAJB11,DNAJC10,DNAJC8,DNTTIP2,DOT1L,DPH3,DPP3,DPPA4,DR1,DROSHA,DTYMK,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EDEM3,EEF1D,EGF,EHMT1,EHMT2,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EOGT,EPN3,ERAP2,ERCC6L,ERLEC1,ERO1A,ESD,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETFA,ETNK1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAM110C,FAM118B,FAM193B,FAM200B,FAM206A,FAM208B,FAM21A,FAM222B,FAM64A,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FAR1,FASTK,FBL,FBXL4,FBXO11,FDXR,FIGNL1,FIP1L1,FKBP4,FKBP6,FLAD1,FLII,FMN2,FNBP4,FUBP1,FUS,FXR1,FZR1,G2E3,GABPB1,GALC,GARS,GATAD2A,GATAD2B,GCAT,GCSH,GEN1,GGA1,GIF,GLA,GLI1,GLRX2,GLS,GLS2,GNL2,GNPAT,GOLGA4,GPBP1,GPC1,GPC3,GPRC5B,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GTPBP10,GZF1,H2AFV,H2AFY,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HEXB,HEYL,HIPK3,HIST1H2BN,HIST2H2AC,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HORMAD1,HOXA10,HOXA9,HOXD11,HS6ST2,HSD17B4,HSF4,HSP90B1,HSPA8,HSPD1,HSPH1,HUS1,HYAL1,HYPK,ICE1,ICE2,IGF2R,IL15,IMPDH1,INCENP,INO80,INO80C,INO80E,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO8,IQCB1,IRF2,ITGB3BP,ITPR1,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KATNBL1,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRI1,KRR1,L3MBTL1,LAMP2,LARP7,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMO2,LNPEP,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTF,LTV1,LUC7L3,MAEA,MAFK,MAGI1,MALSU1,MALT1 847.18 0 0 GO:0043233 organelle lumen cellular_component 4320 1106 AAAS,ABAT,ABCB8,ABCE1,ABHD10,ABTB1,ACACA,ACAD8,ACADVL,ACAT1,ACIN1,ACOT8,ACOT9,ACOX3,ACOXL,ACSF3,ACTL6A,ACTN1,ADA,ADAMTSL1,ADAT2,ADD3,ADK,AFF3,AGO1,AGO2,AHCTF1,AHR,AIP,AK6,AKIP1,AKR1B1,AKT1,AKTIP,ALDH7A1,ALKBH2,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANKRD11,ANKRD12,ANKS1B,ANLN,ANO2,ANP32A,AP5Z1,APBB1,APEX2,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARL2BP,ARMC4,ARPP19,ARSA,ASAH1,ASH1L,ASPSCR1,ASUN,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATOH8,ATP5B,ATP5E,ATP5H,ATR,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,BANP,BAP1,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCHE,BCKDHB,BCKDK,BCLAF1,BIRC3,BLZF1,BMP2K,BMS1,BPTF,BRCA1,BRD4,BRD7,BRIP1,BTBD10,BTN3A3,BUB1B,BUD31,C12orf65,C14orf166,C1D,C1QBP,C2orf88,C8orf44,CABIN1,CADPS2,CALM1,CALU,CAMK2A,CAMK2G,CAND1,CARF,CASK,CASP8,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD2BP2,CD74,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK12,CDK13,CDK5RAP3,CDK7,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP350,CEP57,CEP70,CES1,CFAP20,CHD2,CHD3,CHD6,CHD7,CHFR,CHRAC1,CHTOP,CHUK,CIART,CIR1,CLK2,CLU,CNDP2,CNOT7,COASY,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPS2,COPS3,CPEB1,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRBN,CRCP,CREM,CRNKL1,CROT,CRYAB,CRYM,CS,CSE1L,CSNK2A1,CSNK2A2,CSTF1,CSTF3,CTBP1,CTC1,CTDSPL2,CTNNBL1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,DAG1,DAP3,DAPK3,DARS2,DBF4,DBT,DCAF11,DCAF13,DCAF17,DDB1,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DEPDC1,DGKZ,DHFR,DHRS2,DHX15,DHX40,DIMT1,DLAT,DLD,DMC1,DMTF1,DNA2,DNAJB11,DNAJC10,DNAJC8,DNTTIP2,DOT1L,DPH3,DPP3,DPPA4,DR1,DROSHA,DTYMK,DUSP16,DYNC1LI1,DYRK2,E2F5,E2F7,EAF2,EDEM3,EEF1D,EGF,EHMT1,EHMT2,EIF3B,EIF6,ELAC2,ELF1,ELL2,ELP2,ELP4,EMSY,ENY2,EOGT,EPN3,ERAP2,ERCC6L,ERLEC1,ERO1A,ESD,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETFA,ETNK1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EZH2,FABP5,FAM110C,FAM118B,FAM193B,FAM200B,FAM206A,FAM208B,FAM21A,FAM222B,FAM64A,FAM76B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FAR1,FASTK,FBL,FBXL4,FBXO11,FDXR,FIGNL1,FIP1L1,FKBP4,FKBP6,FLAD1,FLII,FMN2,FNBP4,FUBP1,FUS,FXR1,FZR1,G2E3,GABPB1,GALC,GARS,GATAD2A,GATAD2B,GCAT,GCSH,GEN1,GGA1,GIF,GLA,GLI1,GLRX2,GLS,GLS2,GNL2,GNPAT,GOLGA4,GPBP1,GPC1,GPC3,GPRC5B,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GTPBP10,GZF1,H2AFV,H2AFY,HAT1,HAUS3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HEATR1,HELB,HEXB,HEYL,HIPK3,HIST1H2BN,HIST2H2AC,HLTF,HMGA2,HMGCS1,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HORMAD1,HOXA10,HOXA9,HOXD11,HS6ST2,HSD17B4,HSF4,HSP90B1,HSPA8,HSPD1,HSPH1,HUS1,HYAL1,HYPK,ICE1,ICE2,IL15,IMPDH1,INCENP,INO80,INO80C,INO80E,INTS10,INTS12,INTS6,INTS8,IP6K2,IPO8,IQCB1,IRF2,ITGB3BP,ITPR1,JADE1,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,KATNBL1,KCTD10,KDM1B,KDM5D,KDM6A,KDM7A,KHDRBS3,KIF23,KLHL20,KLHL7,KMT2A,KMT2D,KMT2E,KRI1,KRR1,L3MBTL1,LAMP2,LARP7,LBX1,LEO1,LIG3,LIG4,LIMD1,LIMK1,LIN37,LIN54,LIN9,LITAF,LLGL2,LMO2,LNPEP,LPIN1,LRCH4,LRPPRC,LRRCC1,LSM5,LSM6,LSM8,LTA4H,LTF,LTV1,LUC7L3,MAEA,MAFK,MAGI1,MALSU1,MALT1,MAP1S,MAP2,MAP2K3,MAP3K2,MAPK4,MAPK8,MAPKAPK5,MASTL 836.34 0 0 GO:0005737 cytoplasm cellular_component 10542 2338 AAAS,AAK1,AATK,ABAT,ABCA2,ABCA5,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABI3,ABLIM2,ABLIM3,ABR,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL8,ACTN1,ACTR2,ACYP2,ADA,ADAM10,ADAMTSL1,ADCY10,ADCY4,ADD3,ADGB,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGBL1,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AKAP1,AKAP11,AKAP12,AKAP14,AKAP3,AKAP7,AKR1A1,AKR1B1,AKR1E2,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH3B2,ALDH7A1,ALG13,ALG9,ALOX15,ALPK1,AMBRA1,AMD1,AMDHD2,AMER1,AMPD3,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPTL3,ANK2,ANK3,ANKIB1,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD53,ANKRD6,ANKS1B,ANLN,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APLP1,APOBEC3F,APOO,APPL1,APPL2,APRT,AQP7,ARAP2,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID1B,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARPP21,ARSA,ASAH1,ASB15,ASH1L,ASNS,ASPG,ASPSCR1,ASUN,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATG3,ATG4B,ATIC,ATL2,ATOH8,ATP11B,ATP11C,ATP2A3,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATXN10,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZI2,AZIN2,B3GALNT2,BAG4,BAP1,BAX,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS3,BCHE,BCKDHB,BCKDK,BCL2,BCL2L14,BCLAF1,BET1,BICD1,BIN2,BIRC3,BIRC6,BIRC7,BLNK,BLZF1,BNIP2,BOK,BOLL,BORA,BPIFB3,BPIFB4,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BSN,BTBD10,BTBD2,BTBD9,BTF3,BTG3,BTK,BTN3A3,BUB1B,C10orf67,C11orf21,C12orf4,C12orf65,C14orf159,C14orf166,C15orf39,C16orf62,C16orf89,C19orf68,C1D,C1QBP,C1QTNF5,C2CD5,CA1,CABIN1,CABYR,CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACNB3,CACNB4,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMSAP3,CAMTA1,CAND1,CAPN13,CAPN8,CAPRIN1,CAPS,CAPSL,CAPZA1,CARMIL2,CARS,CASC4,CASK,CASKIN1,CASP4,CASP8,CATIP,CATSPER4,CCDC110,CCDC114,CCDC120,CCDC14,CCDC146,CCDC6,CCDC78,CCDC88A,CCDC88C,CCDC89,CCDC90B,CCDC91,CCDC92,CCNA1,CCNB2,CCNE2,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD247,CD2BP2,CD44,CD46,CD74,CD79B,CD9,CDC123,CDC14B,CDC23,CDC27,CDC42,CDC42EP3,CDC6,CDCA2,CDH1,CDH13,CDK11A,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CECR1,CELSR2,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP350,CEP44,CEP57,CEP57L1,CEP63,CEP70,CEP89,CEP95,CERS2,CES1,CFAP100,CFAP126,CFAP20,CFAP221,CFAP36,CFAP46,CFAP52,CFAP73,CFLAR,CHAC2,CHAD,CHCHD3,CHCHD7,CHD1,CHD3,CHID1,CHIT1,CHMP3,CHMP5,CHMP6,CHN1,CHODL,CHST1,CHUK,CIB2,CIR1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLIP2,CLN3,CLN8,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,CNTN5,COA1,COASY,COBL,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COMMD2,COMMD4,COPA,COPB1,COPS2,COPS3,COQ4,CORO2B,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPA2,CPEB1,CPEB3,CPLX2,CPNE1,CPNE3,CPOX,CPQ,CPS1,CPSF3L,CPT1C,CPT2,CRACR2A,CRBN,CRCP,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK1G1,CSNK2A1,CSNK2A2,CSPP1,CTBP1,CTDNEP1,CTNNA1,CTNNA3,CTNNBL1 2040.91 0 0 GO:0043227 membrane-bounded organelle cellular_component 12061 2611 AAAS,AAK1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABI1,ABTB1,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACE,ACIN1,ACOD1,ACOT8,ACOT9,ACOX3,ACOXL,ACP1,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTL6A,ACTN1,ACTR2,ACTR3C,ACYP2,ADA,ADAM10,ADAMTSL1,ADAT2,ADCY10,ADD3,ADGRG2,ADK,ADNP,ADORA1,ADPGK,AEBP1,AFF3,AGFG1,AGK,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK2,AK6,AKAP1,AKAP11,AKAP3,AKAP7,AKIP1,AKNA,AKR1A1,AKR1B1,AKR1E2,AKT1,AKTIP,ALDH18A1,ALDH1A3,ALDH1L1,ALDH3A2,ALDH7A1,ALG13,ALG9,ALKBH2,ALPL,AMBRA1,AMDHD2,AMER1,AMPH,AMT,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANGPTL3,ANK3,ANKLE2,ANKRD11,ANKRD12,ANKRD13B,ANKRD49,ANKRD6,ANKS1B,ANLN,ANO2,ANO6,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APBB1,APBB2,APEX2,APH1A,APOBEC3B,APOBEC3F,APOO,APPL1,APPL2,APRT,AQR,ARF1,ARFGAP2,ARFRP1,ARGLU1,ARHGAP4,ARHGAP5,ARHGEF12,ARHGEF2,ARID1B,ARID2,ARID4A,ARIH1,ARL1,ARL2BP,ARL6,ARL8A,ARMC1,ARMC3,ARMC4,ARPC1A,ARPC1B,ARPP19,ARSA,ART3,ASAH1,ASB15,ASH1L,ASPSCR1,ASUN,ASXL3,ATAD1,ATAT1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATIC,ATL2,ATMIN,ATOH8,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATPAF1,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AVL9,AZIN2,B3GALNT2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBC3,BBOF1,BBS1,BBS2,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCKDHB,BCKDK,BCL2,BCLAF1,BET1,BICD1,BIRC3,BIRC6,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BOLA2,BPIFB1,BPNT1,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRINP1,BRINP2,BRIP1,BROX,BRWD3,BSN,BTBD10,BTBD7,BTF3,BTK,BTN3A3,BUB1B,BUD31,C10orf67,C12orf65,C14orf159,C14orf166,C16orf62,C16orf89,C17orf80,C19orf68,C1D,C1QBP,C1QTNF5,C1RL,C1S,C2,C2CD5,C2orf88,C4A,C4B,C6orf120,C8orf44,C9orf142,CA1,CABIN1,CABYR,CACNA1A,CACNA2D1,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CALU,CAMK2A,CAMK2G,CAMTA1,CAND1,CAPN8,CAPS,CAPZA1,CARF,CARMIL2,CASC4,CASK,CASP4,CASP8,CATIP,CATSPER4,CBX5,CCDC110,CCDC114,CCDC120,CCDC174,CCDC181,CCDC59,CCDC78,CCDC88A,CCDC89,CCDC90B,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CCT3,CCT7,CCZ1,CCZ1B,CD14,CD163,CD1B,CD22,CD2BP2,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC14B,CDC23,CDC27,CDC42,CDC6,CDCA2,CDH1,CDH13,CDHR1,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKAL1,CDKN3,CDS2,CEACAM5,CELSR1,CENPA,CENPC,CENPJ,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP170,CEP290,CEP350,CEP57,CEP70,CEP89,CERS2,CES1,CFAP100,CFAP126,CFAP157,CFAP20,CFAP221,CFAP36,CFAP46,CFAP73,CFAP77,CFHR3,CHCHD3,CHCHD7,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHIT1,CHL1,CHMP3,CHMP5,CHMP6,CHRAC1,CHST1,CHTOP,CHUK,CIART,CIB2,CIR1,CIZ1,CKAP4,CKMT2,CLASP1,CLASP2,CLCC1,CLCN3,CLDN11,CLEC18A,CLEC2D,CLIP1,CLK2,CLN3,CLN8,CLRN3,CLTA,CLTC,CLU,CMC2,CMIP,CMPK1,CMTR2,CNDP2,CNGA1,CNIH1,CNIH2,CNOT2,CNOT7,CNOT8,CNST,CNTN1,COA1,COASY,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COMMD4,COPA,COPB1,COPS2,COPS3,COQ4,CORO7,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPA2,CPEB1,CPEB3,CPLX2,CPNE1,CPNE3,CPOX,CPQ,CPS1,CPSF3L,CPSF6,CPT1C,CPT2,CR1,CRACR2A,CRAMP1,CRBN,CRCP,CREB5,CREM,CRHBP,CRLS1,CRNKL1,CROT,CRTAC1,CRYAB,CRYM,CS,CSDE1,CSE1L,CSNK1G1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1 2334.98 0 0 GO:0005634 nucleus cellular_component 6835 1620 AAAS,ABCB8,ABCC6,ABI1,ABTB1,ACACA,ACAD11,ACADVL,ACIN1,ACTG1,ACTL6A,ADAM10,ADAT2,ADCY10,ADD3,ADK,ADNP,AEBP1,AFF3,AGFG1,AGO1,AGO2,AGTPBP1,AHCTF1,AHNAK,AHR,AIFM3,AIP,AIPL1,AK6,AKAP3,AKAP7,AKIP1,AKNA,AKR1B1,AKT1,AKTIP,ALDH7A1,ALKBH2,AMDHD2,AMER1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANGEL2,ANGPT2,ANKRD11,ANKRD12,ANKRD49,ANKRD6,ANKS1B,ANLN,ANO2,ANP32A,ANXA2,ANXA4,ANXA7,AP5Z1,APBB1,APBB2,APEX2,APOBEC3B,APOBEC3F,APPL1,APPL2,APRT,AQR,ARGLU1,ARID1B,ARID2,ARID4A,ARIH1,ARL2BP,ARMC1,ARMC3,ARMC4,ARPP19,ASB15,ASH1L,ASPSCR1,ASUN,ASXL3,ATAD1,ATF2,ATF4,ATF7IP,ATF7IP2,ATG16L2,ATMIN,ATOH8,ATP11B,ATP23,ATP2A3,ATP2B1,ATP5B,ATP5H,ATP5J2,ATR,ATRAID,ATRX,ATXN2,ATXN3,ATXN7,AURKA,AURKB,AZIN2,BAG4,BAHCC1,BANP,BAP1,BATF2,BAX,BAZ1A,BAZ2A,BBX,BCAR1,BCAS2,BCAS3,BCCIP,BCHE,BCL2,BCLAF1,BIRC3,BIRC7,BLZF1,BMP2K,BMS1,BNIP2,BOK,BPTF,BRAF,BRCA1,BRD2,BRD3,BRD4,BRD7,BRIP1,BRWD3,BSN,BTBD10,BTBD7,BTF3,BTK,BTN3A3,BUB1B,BUD31,C14orf166,C19orf68,C1D,C1QBP,C2orf88,C8orf44,C9orf142,CABIN1,CABYR,CACNA1A,CACUL1,CADPS2,CALB1,CALCOCO2,CALM1,CAMK2A,CAMK2G,CAMTA1,CAND1,CAPS,CARF,CASK,CASP8,CATIP,CBX5,CCDC110,CCDC174,CCDC181,CCDC59,CCDC89,CCDC91,CCNA1,CCNB2,CCNC,CCNE2,CCNG1,CCNJ,CCNL2,CCNT1,CCNT2,CD2BP2,CD79B,CDC14B,CDC23,CDC27,CDC6,CDCA2,CDK11A,CDK12,CDK13,CDK5RAP3,CDK7,CDKN3,CELSR1,CENPA,CENPC,CENPL,CENPN,CENPQ,CENPU,CEP164,CEP170,CEP290,CEP350,CEP57,CEP70,CERS2,CFAP20,CFAP36,CHCHD3,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHID1,CHMP5,CHRAC1,CHTOP,CHUK,CIART,CIR1,CIZ1,CLCC1,CLIP1,CLK2,CLN3,CLU,CMIP,CMPK1,CMTR2,CNDP2,CNOT2,CNOT7,CNOT8,COASY,COG5,COMMD4,COPS2,COPS3,CPEB1,CPEB3,CPNE1,CPNE3,CPS1,CPSF3L,CPSF6,CPT2,CRACR2A,CRAMP1,CRBN,CRCP,CREB5,CREM,CRHBP,CRNKL1,CRYAB,CRYM,CS,CSE1L,CSNK1G1,CSNK2A1,CSNK2A2,CSRNP3,CSTF1,CSTF3,CTBP1,CTC1,CTDNEP1,CTDSPL2,CTNNBL1,CTNND1,CTR9,CUL1,CUL3,CUL4B,CUX1,CWC22,CWC25,CXADR,CYBB,DAG1,DAP3,DAPK3,DARS2,DBF4,DCAF11,DCAF13,DCAF17,DCAF6,DCAF8,DCTN1,DCTN4,DCUN1D4,DCXR,DDB1,DDIAS,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DENND4A,DEPDC1,DGKZ,DHCR7,DHFR,DHRS2,DHX15,DHX40,DHX57,DICER1,DIMT1,DLD,DMC1,DMPK,DMRT2,DMRTA1,DMTF1,DNA2,DNAJA1,DNAJC1,DNAJC8,DNASE1,DNTTIP2,DOCK7,DOT1L,DPCD,DPF1,DPH1,DPH3,DPP3,DPPA4,DPY19L1,DPY19L3,DPY19L4,DQX1,DR1,DROSHA,DSCR3,DTX1,DTYMK,DUSP16,DUSP9,DYNC1LI1,DYRK2,DYRK4,E2F5,E2F7,EAF2,EAPP,EBF4,ECT2,EDRF1,EEF1B2,EEF1D,EGFR,EHD2,EHMT1,EHMT2,EI24,EIF1,EIF2AK2,EIF2S3,EIF3B,EIF4A1,EIF5B,EIF6,ELAC2,ELF1,ELF3,ELL2,ELP2,ELP4,ELP5,EMC2,EMSY,EMX1,EN1,ENOPH1,ENY2,EPN3,ERCC6L,ERCC6L2,ESF1,ESR1,ESRP1,ESRRB,ESRRG,ETNK1,ETV1,ETV5,ETV6,ETV7,EXOSC8,EYA3,EYA4,EZH2,FABP5,FAF1,FAM107A,FAM110C,FAM111A,FAM118B,FAM156A,FAM175B,FAM193B,FAM200B,FAM206A,FAM208A,FAM208B,FAM21A,FAM222B,FAM58A,FAM64A,FAM76B,FAM81B,FAM96A,FAM98B,FANCA,FANCD2,FANCI,FANCL,FAS,FAT1,FBL,FBXL3,FBXL4,FBXO11,FBXO22,FBXO7,FBXW11,FGF12,FGFR1,FGFR1OP,FHL1,FIGNL1,FILIP1L,FIP1L1,FKBP3,FKBP4,FKBP6,FLII,FMN1,FMN2,FNBP4,FOXJ1,FOXN3,FOXN4,FOXR1,FRA10AC1,FUBP1,FUS,FXR1,FYB,FZR1,G2E3,GABPB1,GADD45G,GARS,GATAD2A,GATAD2B,GCAT,GEN1,GGA1,GGH,GLI1,GLRX2,GNL2,GNPDA2,GOLGA4,GPATCH1,GPBP1,GPBP1L1,GPRC5B,GRHL1,GRHL2,GSK3B,GSN,GSTP1,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3 1323.24 0 0 GO:0012505 endomembrane system cellular_component 3834 823 AAAS,AAK1,ABCA2,ABCA5,ABCC6,ABI1,ACAP1,ACAP2,ACE,ACSBG1,ACSL1,ACTN1,ADAM10,ADAMTSL1,ADORA1,ADPGK,ADPRHL1,ADTRP,AGFG1,AHCTF1,AIFM3,AKAP3,AKTIP,ALDH3A2,ALG13,ALG9,AMPH,ANGPTL3,ANK3,ANKLE2,ANKRD13B,ANP32A,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,APH1A,APOO,APPL1,APPL2,ARF1,ARFGAP2,ARFRP1,ARHGAP4,ARHGAP5,ARHGEF2,ARL1,ARL8A,ARSA,ASH1L,ASPSCR1,ATAT1,ATL2,ATP11B,ATP11C,ATP2A3,ATP2C1,ATP2C2,ATP6V0A4,ATP6V0D1,ATP7B,ATP9B,ATR,ATRAID,ATXN2,ATXN3,AVL9,AZIN2,B3GALNT2,BAX,BCHE,BCL2,BCL2L14,BET1,BICD1,BIRC6,BIRC7,BLZF1,BNIP2,BOK,BRINP1,BRINP2,BRIP1,BTN3A3,C16orf62,C1QTNF5,C2CD5,CACNA2D1,CADPS2,CALU,CAMK2A,CAMK2G,CAND1,CAPN8,CARMIL2,CASC4,CASP4,CATSPER4,CBX5,CCDC110,CCDC120,CCDC78,CCDC88A,CCDC91,CD14,CD163,CD1B,CD44,CD46,CD74,CD79B,CD9,CDC14B,CDC42,CDC42EP3,CDC6,CDH1,CDK13,CDK5RAP3,CDKAL1,CDS2,CEP170,CEP57,CEP70,CERS2,CES1,CHID1,CHMP3,CHMP5,CHMP6,CHST1,CKAP4,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLEC2D,CLIP1,CLN3,CLN8,CLTA,CLTC,CLU,CNIH1,CNIH2,CNST,COG2,COG5,COL17A1,COL23A1,COL4A3,COL4A5,COL6A1,COL9A3,COPA,COPB1,CORO7,CPQ,CPT1C,CRACR2A,CRCP,CRHBP,CRYAB,CSDE1,CSE1L,CTDNEP1,CTNNA1,CUL3,CUX1,CWC22,CXADR,CYBB,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAD1,DBI,DCTN1,DDOST,DEGS1,DENND4C,DHCR7,DHRS2,DLD,DMBT1,DMPK,DMXL2,DNAJB11,DNAJB14,DNAJC1,DNAJC10,DNAJC13,DNASE1,DNM1L,DNM3,DPAGT1,DPY19L1,DPY19L3,DPY19L4,DRAM2,DSCR3,DUOXA1,DYSF,EAPP,EDEM3,EEA1,EEF1B2,EEF1D,EGF,EGFR,EHD2,EI24,ELOVL6,ELOVL7,EMC10,EMC2,ENTPD4,ENTPD6,ENY2,EOGT,EPHA4,EPN3,ERAP2,ERC1,ERLEC1,ERO1A,ESD,ESR1,EVA1A,EXPH5,FADS1,FAF1,FAM156A,FAM21A,FAM76B,FANCL,FAXDC2,FCGR1B,FCHO1,FCHO2,FCHSD1,FES,FEZ1,FGD3,FGD4,FGD6,FKBP3,FKBP4,FKBP6,FKBP8,FMN2,FNBP1,FNBP1L,FNDC3A,FRS2,FTCD,FUT1,FUT8,FUT9,FZD6,FZR1,GAK,GALNT11,GALNT14,GALNT16,GALNT2,GARS,GBA2,GBP5,GCC2,GCGR,GCNT3,GDI2,GGA1,GGCX,GIF,GJB1,GLA,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GORASP2,GPC1,GPC3,GPR89B,GPRC5B,GPSM1,GRHL1,GRIA4,GRINA,GSAP,GTF3C3,GZF1,HACD1,HACD3,HACE1,HAP1,HAVCR2,HDAC6,HEXB,HGS,HHATL,HLA-DMB,HLA-DPB1,HS6ST2,HSD17B3,HSD17B6,HSD17B7,HSP90B1,HSPA8,HSPD1,ICA1,IGF2R,IL15,IL1B,INPP5B,IPO11,IPO8,IPO9,IRAK1,IRAK4,ITM2C,ITPR1,JAM3,JKAMP,KAT6A,KCNIP4,KCNN2,KDELR2,KDSR,KIF13A,KIFC3,KLHL20,KLK11,KTN1,LAMP2,LAMTOR1,LAMTOR3,LAPTM4B,LARP7,LBR,LDAH,LDLRAP1,LFNG,LGR5,LITAF,LMF2,LMNTD1,LNPEP,LPCAT3,LPCAT4,LPGAT1,LPIN1,LRAT,LRBA,LRIG3,LRP6,LRPPRC,LRRC8B,LRRTM1,LSS,LTF,LTV1,M6PR,MAL2,MAN1C1,MAN2A1,MANEA,MANEAL,MAP1LC3B,MAP4K2,MAP6,MAP6D1,MAPK8IP3,MARCH5,MARCH6,MBTPS2,MCF2L,MCFD2,MCTP1,MDM2,MEST,METTL22,MFNG,MFSD2A,MGAT4A,MGAT4B,MGAT4C,MGRN1,MIA3,MINK1,MIP,MITD1,MOXD1,MPHOSPH9,MPPE1,MR1,MRPL19,MRPS23,MSMO1,MTA1,MTDH,MTOR,MTTP,MTUS1,MUC15,MUC4,MVP,MYO18A,MYO1B,MYOC,NAA25,NAA60,NAGPA,NCK1,NDC1,NDRG2,NDUFB4,NEMP2,NFE2L1,NISCH,NKRF,NOS3,NOX1,NOX4,NOX5,NPLOC4,NPTX1,NR3C2,NRAS,NRSN1,NRSN2,NRXN1,NSDHL,NSMAF,NTRK2,NUCB1,NUCB2,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,OCIAD2,OCRL,OLFM1,OPRM1,ORMDL2,ORMDL3,OSBPL1A,OSBPL3,OSBPL5,OSBPL8,OSBPL9,OSTC,P2RX5,P4HA1,PACS2,PAFAH1B1,PAK1,PAK3,PANK1,PAQR3,PARP10,PAX2,PCM1,PCSK5,PCSK7,PCYT1A,PDCD10,PDE2A,PDE6D,PDE9A,PECAM1,PEX16,PEX3,PGAP1,PGAP3 742.25 0.00012 0.00311234042553192 GO:0071013 catalytic step 2 spliceosome cellular_component 88 32 AQR,BCAS2,CRNKL1,CWC22,DDX23,GPATCH1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPH1,HNRNPK,HNRNPM,HNRNPU,MAGOHB,PABPC1,PLRG1,PPIE,PPWD1,PRPF4B,RBMX,RBMX2,SF3B1,SF3B2,SF3B3,SF3B6,SNRNP40,SNRPB2,SNRPE,SNRPF,SRRM2,TFIP11,ZCCHC8 17.04 0.00014 0.00355541666666667 GO:0000118 histone deacetylase complex cellular_component 60 24 APPL1,APPL2,CBX5,CHD3,CIR1,CSNK2A1,GATAD2A,GATAD2B,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MBD3,MORF4L1,NCOR1,NCOR2,PHF12,PHF21A,RBBP4,RBBP7,SAP18,TBL1XR1 11.62 0.00018 0.00447795918367347 GO:0090568 nuclear transcriptional repressor comple... cellular_component 19 11 APPL1,APPL2,CHD3,CSNK2A1,GATAD2A,GATAD2B,HDAC1,HDAC2,MBD3,RBBP4,RBBP7 3.68 0.00023 0.0056074 GO:0097525 spliceosomal snRNP complex cellular_component 54 22 CD2BP2,DDX23,DDX39B,LSM5,LSM6,LSM8,LUC7L,LUC7L3,PRPF18,PRPF39,PRPF40A,RBMX2,SART3,SF3B1,SF3B2,SF3B6,SNRNP40,SNRPB2,SNRPE,SNRPF,SNU13,TXNL4B 10.45 0.00024 0.00573647058823529 GO:0000777 condensed chromosome kinetochore cellular_component 98 34 AHCTF1,BUB1B,CENPA,CENPC,CENPN,CENPU,CLASP1,CLASP2,DCTN6,DYNC1LI1,ERCC6L,FBXO28,INCENP,ITGB3BP,KANSL1,KNTC1,MEAF6,MIS18BP1,NDE1,NSL1,NUP107,NUP37,PHF6,PPP1CC,SEH1L,SEPT2,SEPT7,SGO1,SMC1A,SPAG5,SPDL1,TEX14,ZNF207,ZNF276 18.97 0.00025 0.00575 GO:0016281 eukaryotic translation initiation factor... cellular_component 9 7 EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H 1.74 0.00025 0.00575 GO:0031252 cell leading edge cellular_component 344 93 AAK1,ABI1,ABI3,ABLIM3,ACTN1,ADORA1,AMPH,ANGPTL3,ANTXR1,ANXA2,APBB1,APBB2,ARF1,ARHGEF2,ATF4,ATP2B1,BCAR1,BCAS3,C2CD5,CARMIL2,CCDC88A,CDC42,CDH1,CHRNA7,CLASP2,CLIP1,COBL,CTNNA1,CTNNA3,CTNND1,CYFIP1,DAG1,DCTN1,DGKZ,DYSF,EPB41L3,EPS8L1,EVL,FAT1,FERMT1,FGD3,FGD4,FGD6,HDAC6,ITGAV,ITGB1BP1,ITGB4,KANK1,LCP1,MAPK8IP3,MKLN1,MYH10,MYH9,MYLK,MYO10,MYO1G,OPRM1,PAFAH1B1,PAK1,PALLD,PDE9A,PDLIM7,PIK3CA,PIP5K1A,PIP5K1C,PLEK2,PLXND1,PRKCZ,PSTPIP1,PTK2,PTK2B,PTPN13,PTPRK,PXN,RAB22A,RAB3IP,RAB5A,RAC2,RAPH1,RASGRP2,RUFY3,SH3YL1,SHTN1,SNX2,SNX9,SORBS2,SPATA13,SPTBN1,SSX2IP,TLN1,TRPM7,TWF1,VIL1 66.6 0.00030 0.00677222222222222 GO:0000502 proteasome complex cellular_component 73 27 GET4,MARCH6,PAAF1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSMG2,SHFM1,UBE3A,UBE3C,UCHL5 14.13 0.00033 0.00718339285714286 GO:0000779 condensed chromosome, centromeric region cellular_component 107 36 AHCTF1,AURKA,AURKB,BUB1B,CENPA,CENPC,CENPN,CENPU,CLASP1,CLASP2,DCTN6,DYNC1LI1,ERCC6L,FBXO28,INCENP,ITGB3BP,KANSL1,KNTC1,MEAF6,MIS18BP1,NDE1,NSL1,NUP107,NUP37,PHF6,PPP1CC,SEH1L,SEPT2,SEPT7,SGO1,SMC1A,SPAG5,SPDL1,TEX14,ZNF207,ZNF276 20.71 0.00033 0.00718339285714286 GO:0005739 mitochondrion cellular_component 1648 372 ABAT,ABCB7,ABCB8,ABCE1,ABHD10,ACACA,ACAD11,ACAD8,ACADVL,ACAT1,ACOD1,ACOT8,ACOT9,ACOX3,ACSF3,ACSL1,ACSM6,ACSS3,ACYP2,ADCY10,AGK,AGTPBP1,AIFM3,AK2,AKAP1,AKT1,ALDH18A1,ALDH1L1,ALDH3A2,ALDH7A1,AMBRA1,AMT,ANXA6,APEX2,APOO,ARGLU1,ARL2BP,ARMC1,ATAD1,ATF2,ATIC,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP7B,ATPAF1,ATXN3,AZIN2,BAX,BBC3,BCKDHB,BCKDK,BCL2,BOK,BRAF,C10orf67,C12orf65,C14orf159,C1QBP,CAMK2A,CASP4,CASP8,CCDC90B,CCT7,CDK7,CDS2,CEP89,CHCHD3,CHCHD7,CKMT2,CLN3,CLU,CMC2,COA1,COASY,COQ4,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT1C,CPT2,CRLS1,CROT,CRYAB,CRYM,CS,CSDE1,CXorf23,CYBB,DAP3,DARS2,DBT,DDX6,DEGS1,DHRS2,DHX57,DIABLO,DIMT1,DLAT,DLD,DMPK,DNA2,DNAJA1,DNM1L,DNM3,DTYMK,ELAC2,EMC2,ENOSF1,EPHA4,ERCC6L2,ETFA,FADS1,FAM65B,FASTK,FBXL4,FBXO7,FDXR,FEZ1,FKBP4,FKBP8,FLAD1,GARS,GBAS,GCAT,GCSH,GLRX2,GLS,GLS2,GNPAT,GSK3B,GSTP1,GTPBP10,HACD3,HAP1,HARS,HAUS3,HEATR1,HSD17B4,HSPD1,IMMP2L,KANK2,KIAA1683,KIF1BP,KRAS,KRT5,LACE1,LETM2,LETMD1,LIG3,LPIN1,LRPPRC,LYPLA1,LYRM5,MAATS1,MALSU1,MAP1LC3B,MAPK8,MARCH5,MCUR1,MDH1,MFF,MFN1,MLXIP,MMAA,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MSRA,MSTO1,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTFR1,MTG1,MTHFD1,MTHFD2L,MTIF2,MTIF3,MT-ND4,MT-ND4L,MTO1,MTOR,MTRF1,MTRF1L,MTUS1,MTX1,MTX2,MTX3,MUTYH,MYH10,MYOC,MYOM2,NAPG,NARS,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFAF7,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NEU4,NFU1,NIF3L1,NIT2,NME4,NME6,NMNAT3,NMT1,NNT,NOX4,NR3C1,NSUN4,NUDT6,NUDT9,NVL,OCIAD2,OGT,OMA1,OPA1,OXNAD1,P2RY12,P4HA1,PACS2,PALLD,PCK2,PDE2A,PDHB,PDK3,PDSS1,PFDN2,PHYKPL,PIN1,PKM,PLA2G4B,PMPCB,PNKP,PNPT1,POLD3,PON2,POR,PPP1CC,PPP2R1A,PPTC7,PRDX4,PRELID3A,PROSC,PRR5L,PTCD3,PTEN,PTRH2,PTS,PYCR1,QDPR,QTRT1,RAD51C,RAI14,RANBP2,RAP1GDS1,RARS,RARS2,RDH13,REEP1,REXO2,RHBDD1,RHBDL3,RHOT1,RMDN1,RPL35A,RPS6KA6,RPS6KB1,RPUSD1,RPUSD4,RRM2B,RUNX1T1,SDHAF2,SDHC,SDHD,SEPT4,SGK1,SHMT2,SIRT5,SLC11A2,SLC25A13,SLC25A17,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A46,SLC25A48,SLC8B1,SPATA18,SPATA5,SPG7,SRI,SRP19,SSBP1,STAR,STARD4,STARD7,SUCLG1,SURF1,TAZ,TBC1D15,TEFM,TFB1M,THOP1,TIGAR,TIMM10B,TIMM23B,TIMM50,TMBIM6,TMEM70,TNRC18,TOMM20,TP63,TRAK1,TRMT10C,TRMT1L,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH,VDAC3,VPS13C,WARS2,WWOX,XPNPEP3,XRCC3,YKT6,YRDC,YWHAQ,YWHAZ,ZDHHC8 319.05 0.00036 0.00769894736842105 GO:0031597 cytosolic proteasome complex cellular_component 12 8 PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD2,UCHL5 2.32 0.00046 0.00966793103448276 GO:0030496 midbody cellular_component 133 42 ANXA2,ARL2BP,ARL8A,AURKA,AURKB,BIRC6,CDC42,CEP44,CTNND1,CYLD,ECT2,FAM175B,HSP90B1,INCENP,KIF13A,KIF23,KLHL13,LZTS2,MITD1,MYH10,PIK3C3,PIN1,PKP4,PPP1CC,PRC1,RACGAP1,RALB,RNF8,SDCCAG3,SEPT1,SEPT2,SEPT7,SIRT2,SPAG5,TACC1,TEX14,TRIOBP,TTC19,USP8,UVRAG,VPS4A,ZNF330 25.75 0.00052 0.0107437288135593 GO:0044463 cell projection part cellular_component 929 219 AAK1,ABI1,ADA,ADAM10,ADCY10,ADCYAP1,ADORA1,AK2,AKAP3,AKR1B1,AKT1,AMBRA1,ANK3,ANKS1B,ANTXR1,APBB1,APBB2,ARF1,ARHGAP4,ARHGEF2,ARL6,ARMC4,ARPC1A,ASIC2,ATF4,ATP2B1,ATP2B4,ATP6V0A4,ATP6V0D1,AURKA,BBOF1,BBS1,BBS2,BOC,BSN,C2CD5,CABYR,CACNA1C,CALB1,CALM1,CASK,CATSPER4,CCDC114,CCDC120,CDH8,CDHR1,CENPJ,CEP290,CFAP126,CFAP20,CFAP221,CFAP46,CHRM2,CHRNA3,CHRNA7,CLASP2,CNGA1,CNIH2,COBL,CPEB1,CPLX2,CRHBP,CRTAC1,CRYAB,CTNND1,CTTNBP2,CXADR,CYLD,DAAM1,DAB2IP,DAG1,DCTN2,DDX6,DICER1,DLG2,DLG3,DLGAP1,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNAJB13,DNALI1,DNM3,DOCK7,DRC1,EEA1,EPB41L3,EPHA4,EPS8L1,ERC2,EXOC4,FAM161A,FAM65B,FARP1,FERMT1,FKBP4,FUS,FXR1,GLI1,GNA12,GNGT1,GPM6A,GRID2IP,GRM5,GRM7,GSK3B,HOMER3,HSPB11,ITGA2,ITGAV,ITPR1,JADE1,KANK1,KCNA6,KCNAB2,KCNN2,KNCN,LCP1,LDLRAP1,LRRTM1,MAP1LC3B,MAP2K4,MAP3K12,MAPK8IP3,MINK1,MKS1,MME,MOB2,MPDZ,MYH10,MYO10,MYOC,NAPEPLD,NDRG2,NECTIN1,NOX1,NRSN1,NTRK2,OFD1,OLFM1,OPRK1,OPRM1,OSBPL3,PAFAH1B1,PAK1,PALLD,PCM1,PDE6B,PDE9A,PDZK1,PFN2,PICK1,PIK3C3,PIP5K1A,PIP5K1C,PKP4,PLCB4,PLEK2,POC1B,PPP1CC,PRKCZ,PROM1,PSD3,PTBP2,PTEN,PTH1R,PTK2B,PTPRN,RAB5A,RASGRP2,RGS14,RP2,RPGR,RSPH9,RTTN,RUFY3,SEPT2,SEPT4,SEPT5,SEPT7,SEPT9,SH3YL1,SHANK2,SHTN1,SIRT2,SLC11A2,SLC12A5,SLC34A1,SLC5A1,SLC6A19,SOS1,SPAG16,SPATA13,SPTBN1,SPTBN4,SRI,SSX2IP,STMN4,STRN,SYNPO,SYT1,TAPT1,TAS2R4,TBC1D10C,THY1,TLN1,TMEM237,TMEM57,TMEM67,TRPM6,TTC21B,TTYH1,TWF1,USH2A,USP9X,VIL1 179.85 0.00062 0.0125963333333333 GO:0030532 small nuclear ribonucleoprotein complex cellular_component 61 23 CD2BP2,DDX23,DDX39B,LSM5,LSM6,LSM8,LUC7L,LUC7L3,PRPF18,PRPF39,PRPF40A,RBMX2,SART3,SF3B1,SF3B2,SF3B3,SF3B6,SNRNP40,SNRPB2,SNRPE,SNRPF,SNU13,TXNL4B 11.81 0.00065 0.0129893442622951 GO:0022624 proteasome accessory complex cellular_component 24 12 PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,SHFM1 4.65 0.00071 0.0139314285714286 GO:0005838 proteasome regulatory particle cellular_component 21 11 PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,SHFM1 4.07 0.00072 0.0139314285714286 GO:0048471 perinuclear region of cytoplasm cellular_component 620 152 AATK,ADAM10,ADCY10,AKR1B1,AMBRA1,ANP32A,ANXA2,ANXA4,ANXA6,APBB1,APLP1,ARF1,ASPSCR1,ATP7B,ATP9B,ATRAID,ATXN10,ATXN2,AURKA,AZIN2,BICD1,BNIP2,BPTF,BTK,BUB1B,C14orf166,CALCOCO2,CCDC78,CCNT2,CDH1,CDH13,CDK7,CDKN3,CHODL,CKAP4,CLU,COBL,CYBB,CYFIP1,CYLD,DNAJA1,DNM1L,DNM3,EGFR,EHD2,EIF2AK2,EIF4A2,EIF4E,EIF4H,EPN3,FAF1,FAT1,FGFR1OP,FKBP4,FMN2,FUS,FXR1,GAK,GALNT2,GSK3B,HDAC1,HDAC6,HERC5,HHATL,HSP90B1,IGF2R,ITGA2,ITGB1BP1,ITM2C,KLHL20,LAMC2,LNPEP,LRAT,LRPPRC,M6PR,MAL2,MALT1,MAP1S,MAP6,MEIS2,MLPH,MOB2,MOSPD1,MTDH,MVP,MYO16,MYO1B,NDRG2,NOX4,OSBPL3,PAFAH1B1,PAK2,PDE2A,PDE9A,PICK1,PKP4,PLA2G5,PLD1,PRKCZ,PSTPIP1,PTK2B,PTOV1,PUM2,RAB40B,RAD51C,RAP1A,RAP1GAP2,RAPGEF2,RASA2,RHBDD2,ROS1,RPS6KB1,RYR3,SCYL2,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEPT2,SEPT9,SERBP1,SERINC3,SHTN1,SIPA1,SIRT2,SLC11A2,SLC34A1,SLC39A13,SNAPIN,SORBS2,SPAG9,STX8,SYT5,TARBP2,TF,TFRC,TGFA,TLK2,TNFSF12,TPD52,TRAF4,TRAPPC2B,TRIP10,TWF1,USP33,VPS4A,VPS54,WDR44,XRCC3,YBX3,ZNF35 120.03 0.00076 0.014475625 GO:0030427 site of polarized growth cellular_component 136 42 ABI1,ADCY10,APBB1,APBB2,ARHGAP4,BOC,CALM1,CCDC120,COBL,CRTAC1,CTNND1,CXADR,DCTN2,DICER1,DLG3,DOCK7,EPHA4,ERC2,EXOC4,FKBP4,FRY,FRYL,GPM6A,GSK3B,LRRTM1,MAP3K12,MYH10,NDRG2,NECTIN1,NRSN1,OLFM1,PAFAH1B1,PALLD,PTBP2,PTK2B,RUFY3,SHANK2,SHTN1,SIRT2,STMN4,THY1,USP9X 26.33 0.00086 0.0161283076923077 GO:0005802 trans-Golgi network cellular_component 190 55 AMPH,AP1G1,AP1M2,AP1S2,ARF1,ARFRP1,ARL1,ATP2C1,ATP7B,ATP9B,ATXN2,AZIN2,BICD1,BIRC6,BOK,CD74,CDH1,CHID1,CLASP2,CLN3,CLTA,CLTC,CNST,COG2,COG5,CORO7,FNBP1,FNBP1L,GCC2,GOLGA4,GSAP,HLA-DPB1,IGF2R,KIF13A,KLHL20,LGR5,M6PR,MYO18A,MYO1B,NCK1,NUCB1,OCRL,RAB30,RIC1,SCAMP5,SCOC,SNX9,SOD3,SORL1,STX8,TMEM165,TRIP10,USP6NL,VAMP4,VPS54 36.78 0.00089 0.0164380303030303 GO:0005740 mitochondrial envelope cellular_component 706 170 ABCB7,ABCB8,ACAD11,ACADVL,ACAT1,ACSL1,AGK,AIFM3,AK2,AKAP1,ALDH18A1,ALDH3A2,AMBRA1,APOO,ARL2BP,ATF2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATXN3,BAX,BCL2,BOK,CASP8,CCDC90B,CDS2,CEP89,CHCHD3,CHCHD7,CKMT2,CLU,COA1,COASY,COQ4,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT1C,CPT2,CRLS1,CSDE1,DAP3,DIABLO,DMPK,DNM1L,DNM3,DTYMK,EPHA4,FBXL4,FKBP8,GCAT,HSPD1,IMMP2L,LETM2,LETMD1,LPIN1,MARCH5,MCUR1,MFF,MFN1,MLXIP,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MSTO1,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD2L,MT-ND4,MT-ND4L,MTOR,MTX1,MTX2,MTX3,MYOC,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NME4,NNT,OCIAD2,OMA1,OPA1,PLA2G4B,PMPCB,PNPT1,PPP1CC,PRELID3A,PTCD3,QTRT1,RDH13,REEP1,REXO2,RHBDL3,RHOT1,RPS6KB1,SDHC,SDHD,SHMT2,SIRT5,SLC11A2,SLC25A13,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A46,SLC25A48,SLC8B1,SPATA18,SPG7,STAR,SUCLG1,SURF1,TAZ,THOP1,TIGAR,TIMM10B,TIMM23B,TIMM50,TMBIM6,TMEM70,TOMM20,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH,VDAC3,VPS13C 136.68 0.00092 0.0167385074626866 GO:0019773 proteasome core complex, alpha-subunit c... cellular_component 8 6 PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6 1.55 0.00102 0.0179367142857143 GO:0031595 nuclear proteasome complex cellular_component 8 6 PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD12 1.55 0.00102 0.0179367142857143 GO:0035770 ribonucleoprotein granule cellular_component 129 40 AGO1,AGO2,APOBEC3F,ATXN2,BTBD2,CAPRIN1,CNOT2,CNOT7,CPEB1,DDX1,DDX6,EDC3,EIF4E,EXD1,FXR1,GRB7,HNRNPA3,HNRNPL,LIMD1,LSM6,MBNL1,OGFOD1,PABPC1,PAN3,PIWIL4,PNRC2,POLR2G,PSMA2,PSMA4,PSMA6,PSMC2,PUM2,RBM4,RBPMS,TDRD5,TDRD6,TIA1,TIAL1,TRIM5,ZC3H12A 24.97 0.00103 0.0179367142857143 GO:0019866 organelle inner membrane cellular_component 533 132 ABCB7,ABCB8,ACAD11,ACADVL,ACAT1,AIFM3,AK2,ALDH18A1,ALDH3A2,APOO,ATP11B,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,BOK,CDS2,CHCHD3,CKMT2,COA1,COQ4,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT2,CRLS1,CSDE1,DAP3,DPY19L1,DPY19L3,DPY19L4,GCAT,HSPD1,IMMP2L,ITPR1,LBR,LETM2,LETMD1,LRPPRC,MCUR1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD2L,MT-ND4,MT-ND4L,MYOC,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NEMP2,NEU4,NME4,NNT,OCIAD2,OMA1,OPA1,P2RX5,PLA2G4B,PMPCB,PTCD3,RDH13,RHBDL3,RNF13,SDHC,SDHD,SHMT2,SIRT5,SLC25A13,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A48,SLC8B1,SPG7,STAR,SUCLG1,SURF1,TAZ,TERB2,TIMM10B,TIMM23B,TIMM50,TMEM70,TMPO,TOR1AIP1,TRA2B,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH 103.19 0.00108 0.0185425352112676 GO:0000228 nuclear chromosome cellular_component 502 125 ACTL6A,ADD3,ATR,ATRX,AURKA,AURKB,BCAS2,BRCA1,BRD4,BUB1B,BUD31,CBX5,CENPA,CENPC,CHRAC1,CSNK2A1,CTC1,DDB1,DMC1,DNA2,EHMT2,ESR1,EZH2,FIGNL1,FKBP6,GATAD2B,H2AFV,H2AFY,HAT1,HDAC1,HDAC2,HDAC8,HELB,HIST1H2BN,HIST2H2AC,HMGA2,HNRNPC,HNRNPK,HORMAD1,HUS1,INCENP,INO80,INO80C,INO80E,JUND,LIG4,LRPPRC,MBD3,MCM2,MCMBP,MEF2A,MIS18BP1,MMS22L,MORF4L1,MSH5,NASP,NAT10,NCOA1,NCOR1,NCOR2,NFATC1,NPM2,NUCKS1,ORC4,PAWR,PHF12,PLCB1,PLRG1,PMS1,POLA1,POLA2,POLD3,POLD4,POT1,PPP1CB,PPP1CC,PURA,RAD51AP1,RAD51C,RBBP4,RBMX,RNF2,RNF212,RPA3,RXRA,SGO1,SIRT2,SIRT6,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCAD1,SMARCD2,SMARCE1,SMC1A,SMC2,SMCHD1,SP1,SSB,STAG3,STAT6,SYCP3,TCF12,TCF7,TCP1,TERB2,TEX11,TFIP11,THOC1,THOC2,THOC7,TNKS,TOPBP1,TP63,TTC21B,UBE2B,UCHL5,USP3,WAPL,WRN,XRCC3,XRCC5,ZNF385A,ZRANB3 97.19 0.00116 0.0196394444444444 GO:0030061 mitochondrial crista cellular_component 6 5 COX6B2,HSPD1,OPA1,SLC8B1,STAR 1.16 0.00137 0.022567972972973 GO:0031265 CD95 death-inducing signaling complex cellular_component 6 5 CASP8,CFLAR,FADD,FAF1,FAS 1.16 0.00137 0.022567972972973 GO:0030426 growth cone cellular_component 131 40 ABI1,ADCY10,APBB1,APBB2,ARHGAP4,BOC,CALM1,CCDC120,COBL,CRTAC1,CTNND1,CXADR,DCTN2,DICER1,DLG3,DOCK7,EPHA4,ERC2,EXOC4,FKBP4,GPM6A,GSK3B,LRRTM1,MAP3K12,MYH10,NDRG2,NECTIN1,NRSN1,OLFM1,PAFAH1B1,PALLD,PTBP2,PTK2B,RUFY3,SHANK2,SHTN1,SIRT2,STMN4,THY1,USP9X 25.36 0.00143 0.0232422666666667 GO:0016605 PML body cellular_component 95 31 ATR,ATRX,CBX5,CHFR,CIART,DAPK3,HIPK3,KAT6A,KLHL20,LRCH4,MTOR,N4BP1,NR2C1,NSMCE2,PIAS1,PTEN,RDM1,RFWD3,RGS14,RNF4,RNF6,SENP2,SMC6,SP3,SPTBN4,SUMO1,SUMO2,TOPBP1,USP7,ZMYM2,ZNF451 18.39 0.00147 0.0235780263157895 GO:0005844 polysome cellular_component 39 16 AGO1,AGO2,ATXN2,DRG1,EIF4B,EIF4H,FUS,FXR1,IMPACT,MSI1,MSI2,PSMA1,PSMA6,UNK,VBP1,YBX3 7.55 0.00149 0.0235884415584416 GO:0098796 membrane protein complex cellular_component 1087 249 AAAS,ABCA2,ABCB8,AGFG1,AHCTF1,AKTIP,ANO2,ANO6,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,APH1A,ARL6,ATP1B1,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,BAX,BCL2,BET1,C1orf101,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CACNB3,CACNB4,CACNG6,CALM1,CASP8,CATSPER4,CD14,CD247,CD3G,CD6,CD74,CD79B,CDH1,CFLAR,CHMP3,CHMP6,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHUK,CLCC1,CLCN1,CLCNKA,CLTA,CLTC,CNIH2,COPA,COPB1,COX5A,COX6A1,CPLX2,CPT1C,CTDNEP1,CTNNA1,CYBB,DAD1,DAG1,DCTN1,DDOST,DIABLO,DLG2,DLG3,EGFR,EMC10,EMC2,ENY2,FADD,FAF1,FAS,FXYD1,GABBR1,GABRA5,GABRE,GABRG3,GABRP,GGA1,GJB1,GJC2,GLRA3,GNA12,GNA14,GNG4,GNG7,GNGT1,GRIA4,HLA-DMB,HLA-DPB1,HOOK1,HSPD1,IGF1R,IGF2R,IMMP2L,IRAK1,ITGA2,ITGA6,ITGA7,ITGAL,ITGAV,ITGB4,ITGB6,ITGB8,KCNA6,KCNAB2,KCNB1,KCNIP4,KCNK6,KCNMA1,LAMTOR1,LAMTOR3,LDLRAP1,LTV1,M6PR,MARCH6,MR1,MT-ATP6,MT-CO1,MT-CO2,MT-CO3,MT-ND4,MT-ND4L,MTOR,MVP,MYH9,NAPB,NAPG,NDC1,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NECTIN1,NOX1,NOX4,NPLOC4,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,ORMDL2,ORMDL3,OSMR,OSTC,PANK1,PDE4D,PIGT,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PMPCB,PTK2B,PTPN6,RAE1,RANBP2,RGS6,RP9,RPN2,RRAGB,RYR2,RYR3,SACM1L,SCAMP5,SCFD1,SCN11A,SCN3B,SCNN1B,SDCBP,SDCCAG3,SDHC,SDHD,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEH1L,SENP2,SGIP1,SHANK2,SLC38A9,SNAP23,SNTG2,SNX2,SNX4,SPG7,STX5,STX8,STXBP2,SUMO1,SYT1,TBC1D5,TGFBR1,TIMM23B,TIMM50,TLR1,TNK2,TNKS,TOMM20,TRADD,TRIP6,TSPAN32,TTYH1,UQCRB,UQCRC2,UVRAG,VAMP4,VDAC3,VPS11,VPS29,VPS36,VPS4A,XPO7,XPOT,YKT6,ZAP70 210.44 0.00152 0.0237548717948718 GO:0016442 RISC complex cellular_component 11 7 AGO1,AGO2,DDX6,DICER1,EIF4E,LIMD1,TARBP2 2.13 0.00160 0.02438 GO:0031332 RNAi effector complex cellular_component 11 7 AGO1,AGO2,DDX6,DICER1,EIF4E,LIMD1,TARBP2 2.13 0.00160 0.02438 GO:0036464 cytoplasmic ribonucleoprotein granule cellular_component 120 37 AGO1,AGO2,APOBEC3F,ATXN2,BTBD2,CAPRIN1,CNOT2,CNOT7,CPEB1,DDX1,DDX6,EDC3,EIF4E,EXD1,GRB7,LIMD1,LSM6,MBNL1,OGFOD1,PABPC1,PAN3,PIWIL4,PNRC2,POLR2G,PSMA2,PSMA4,PSMA6,PSMC2,PUM2,RBM4,RBPMS,TDRD5,TDRD6,TIA1,TIAL1,TRIM5,ZC3H12A 23.23 0.00174 0.026015243902439 GO:0030286 dynein complex cellular_component 43 17 CCDC114,DCTN1,DCTN2,DCTN4,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNALI1,DYNC1I2,DYNC1LI1,HDAC6,SNX4 8.32 0.00175 0.026015243902439 GO:0031966 mitochondrial membrane cellular_component 665 159 ABCB7,ABCB8,ACAD11,ACADVL,ACAT1,ACSL1,AGK,AIFM3,AK2,AKAP1,ALDH18A1,ALDH3A2,AMBRA1,APOO,ATF2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATXN3,BAX,BCL2,BOK,CASP8,CCDC90B,CDS2,CHCHD3,CKMT2,CLU,COA1,COASY,COQ4,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT1C,CPT2,CRLS1,CSDE1,DAP3,DMPK,DNM1L,DNM3,EPHA4,FKBP8,GCAT,HSPD1,IMMP2L,LETM2,LETMD1,LPIN1,MARCH5,MCUR1,MFF,MFN1,MLXIP,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MSTO1,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD2L,MT-ND4,MT-ND4L,MTOR,MTX1,MTX2,MTX3,MYOC,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NME4,NNT,OCIAD2,OMA1,OPA1,PLA2G4B,PMPCB,PPP1CC,PTCD3,QTRT1,RDH13,REEP1,RHBDL3,RHOT1,RPS6KB1,SDHC,SDHD,SHMT2,SIRT5,SLC11A2,SLC25A13,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A46,SLC25A48,SLC8B1,SPATA18,SPG7,STAR,SUCLG1,SURF1,TAZ,TIGAR,TIMM10B,TIMM23B,TIMM50,TMBIM6,TMEM70,TOMM20,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH,VDAC3,VPS13C 128.74 0.00180 0.0263877647058824 GO:0032153 cell division site cellular_component 54 20 ANLN,ECT2,MAEA,MASTL,MYH10,MYH9,MYLK,NDE1,PLCD3,PLEKHG6,PLK4,PPP1CC,PSTPIP1,RACGAP1,RHOC,SEPT2,SEPT7,STAMBP,TUBGCP5,WDR73 10.45 0.00184 0.0263877647058824 GO:0032155 cell division site part cellular_component 54 20 ANLN,ECT2,MAEA,MASTL,MYH10,MYH9,MYLK,NDE1,PLCD3,PLEKHG6,PLK4,PPP1CC,PSTPIP1,RACGAP1,RHOC,SEPT2,SEPT7,STAMBP,TUBGCP5,WDR73 10.45 0.00184 0.0263877647058824 GO:0090544 BAF-type complex cellular_component 23 11 ACTL6A,ARID1B,ARID2,BRD7,DPF1,NCR1,SMARCA2,SMARCD1,SMARCD2,SMARCE1,SS18 4.45 0.00189 0.0267896511627907 GO:0010494 cytoplasmic stress granule cellular_component 33 14 ATXN2,CAPRIN1,DDX1,DDX6,EIF4E,GRB7,MBNL1,OGFOD1,PABPC1,PUM2,RBM4,RBPMS,TIA1,TIAL1 6.39 0.00199 0.0277045454545455 GO:0097458 neuron part cellular_component 1193 270 AAK1,ABAT,ABI1,ADA,ADAM10,ADAM22,ADCY10,ADCY4,ADCYAP1,ADNP,ADORA1,AGFG1,AGO2,AIPL1,AMPH,ANK2,ANK3,ANKS1B,APBB1,APBB2,ARF1,ARHGAP4,ARHGEF15,ARHGEF2,ARID1B,ARIH1,ASIC2,ATAT1,ATF4,ATP2B1,ATP2B4,ATP6V0D1,ATXN10,AURKA,AZIN2,BMPR1B,BOC,BPTF,BRAF,BRINP1,BRINP2,BSN,C4A,C4B,CACNA1A,CACNA1C,CADPS2,CALB1,CALM1,CAMK2A,CAPRIN1,CASK,CASP8,CCDC120,CDC42,CDH13,CDH8,CDHR1,CHL1,CHRM2,CHRNA3,CHRNA7,CIB2,CLCN3,CLN3,CLU,CNGA1,CNIH2,COBL,CPEB1,CPEB3,CPLX2,CPT1C,CRHBP,CRTAC1,CRYAB,CTNND1,CTTNBP2,CXADR,CYBB,CYFIP1,DAB2IP,DAG1,DCC,DCTN2,DICER1,DLG2,DLG3,DLGAP1,DMXL2,DNM1L,DNM3,DOCK7,DPF1,DRAM2,DTNA,EEA1,EPB41L3,EPHA4,EPHB2,ERC1,ERC2,ERO1A,EXOC4,FADD,FAM107A,FAM206A,FARP1,FAS,FBXO7,FEZ1,FEZ2,FKBP4,FUS,FXR1,GABBR1,GABRA5,GARS,GLRA3,GLRX2,GNGT1,GPM6A,GRIA4,GRID2IP,GRM5,GRM7,GRM8,GSK3B,GTF2I,HAP1,HDAC1,HDAC6,HNRNPA3,HOMER3,HTR2B,ICA1,IQCB1,ITGA2,ITPR1,KCNA6,KCNAB2,KCNB1,KCNN2,KLHL20,KLHL24,KNCN,LDLRAP1,LIMK1,LRP6,LRRTM1,LYNX1,MAGOHB,MAP1S,MAP2,MAP2K4,MAP3K12,MAPK8IP3,MFF,MINK1,MLPH,MME,MOB2,MPDZ,MTOR,MYH10,MYOC,NAPEPLD,NCOA1,NDRG2,NECTIN1,NF1,NGDN,NRSN1,NRSN2,NRXN1,NTRK2,OCRL,OLFM1,OPA1,OPRK1,OPRM1,PAFAH1B1,PAK1,PALLD,PDE1B,PDE2A,PDE6B,PDE9A,PFN2,PICK1,PIN1,PKP4,PLCB4,PLK3,PPFIA2,PPFIA4,PPP1CC,PPP1R1B,PRKCZ,PROM1,PSD3,PTBP2,PTEN,PTK2B,PTPN13,PTPRK,PTPRN,PURA,QDPR,RAB5A,RAP1A,RAP1GAP2,RAPGEF2,RASGRP2,RELN,RGS14,RIMS1,RNF6,ROBO1,ROBO3,RPGR,RPLP0,RPS6KB1,RUFY3,SCAMP5,SCN11A,SEPT5,SHANK2,SHTN1,SIRT2,SLC12A5,SLC1A3,SLC25A27,SLC30A3,SLC38A2,SLC6A13,SMARCA2,SMARCD1,SMARCE1,SNAP23,SNAPIN,SNX14,SOS1,SPTBN1,SPTBN4,SRI,STAR,STMN4,STRN,SUMO1,SYN2,SYNPO,SYNPR,SYPL2,SYT1,SYT5,TGFB1,THY1,TMEM57,TP63,TPGS1,UFL1,USH1C,USH2A,USP9X,WRN,YKT6,ZDHHC17,ZNF385A,ZNRF2 230.96 0.00200 0.0277045454545455 GO:0044429 mitochondrial part cellular_component 966 222 ABAT,ABCB7,ABCB8,ABCE1,ABHD10,ACAD11,ACAD8,ACADVL,ACAT1,ACOT9,ACSF3,ACSL1,AGK,AIFM3,AK2,AKAP1,ALDH18A1,ALDH3A2,ALDH7A1,AMBRA1,AMT,APOO,ARL2BP,ATF2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATXN3,BAX,BCKDHB,BCKDK,BCL2,BOK,C12orf65,C1QBP,CASP8,CCDC90B,CDS2,CEP89,CHCHD3,CHCHD7,CKMT2,CLU,COA1,COASY,COQ4,COX17,COX20,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT1C,CPT2,CRLS1,CS,CSDE1,DAP3,DARS2,DBT,DHRS2,DIABLO,DIMT1,DLAT,DLD,DMPK,DNA2,DNM1L,DNM3,DTYMK,ELAC2,EPHA4,ETFA,FASTK,FBXL4,FDXR,FKBP8,FLAD1,GARS,GCAT,GCSH,GLRX2,GLS,GLS2,HSPD1,IMMP2L,LETM2,LETMD1,LPIN1,LRPPRC,MALSU1,MARCH5,MCUR1,MFF,MFN1,MLXIP,MMAA,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MSTO1,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD2L,MT-ND4,MT-ND4L,MTOR,MTRF1L,MTX1,MTX2,MTX3,MYOC,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFAF7,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NME4,NNT,NR3C1,NSUN4,NUDT9,OCIAD2,OMA1,OPA1,PCK2,PDE2A,PDHB,PDK3,PDSS1,PHYKPL,PLA2G4B,PMPCB,PNPT1,PPP1CC,PRELID3A,PTCD3,PYCR1,QTRT1,RARS2,RDH13,REEP1,REXO2,RHBDL3,RHOT1,RPS6KB1,SDHAF2,SDHC,SDHD,SHMT2,SIRT5,SLC11A2,SLC25A13,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A46,SLC25A48,SLC8B1,SPATA18,SPG7,SSBP1,STAR,SUCLG1,SURF1,TAZ,TEFM,TFB1M,THOP1,TIGAR,TIMM10B,TIMM23B,TIMM50,TMBIM6,TMEM70,TOMM20,TRMT10C,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH,VDAC3,VPS13C,WARS2 187.02 0.00228 0.0312283146067416 GO:0030027 lamellipodium cellular_component 168 48 ABI1,ABI3,ABLIM3,ANGPTL3,ANTXR1,APBB1,APBB2,BCAR1,CARMIL2,CCDC88A,CDH1,CTNNA1,CTNNA3,CTNND1,CYFIP1,DAG1,DGKZ,DYSF,EVL,FAT1,FGD3,FGD4,FGD6,ITGAV,ITGB1BP1,MYH10,MYLK,MYO10,MYO1G,PALLD,PIK3CA,PIP5K1A,PLEK2,PLXND1,PSTPIP1,PTK2,PTK2B,PTPN13,PXN,RAB3IP,RAC2,RAPH1,RUFY3,SHTN1,SNX2,SORBS2,SPATA13,VIL1 32.52 0.00243 0.032913 GO:0005677 chromatin silencing complex cellular_component 9 6 BAHCC1,BAZ2A,RRP8,SIRT2,SMARCA5,TNRC18 1.74 0.00257 0.0337170212765957 GO:0031264 death-inducing signaling complex cellular_component 9 6 CASP8,CFLAR,FADD,FAF1,FAS,TRADD 1.74 0.00257 0.0337170212765957 GO:0008287 protein serine/threonine phosphatase com... cellular_component 48 18 CTDNEP1,ITPR1,NCK1,NKD1,PPP1CB,PPP1CC,PPP1R12A,PPP1R2P3,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP4R3B,STRN 9.29 0.00260 0.0337170212765957 GO:1903293 phosphatase complex cellular_component 48 18 CTDNEP1,ITPR1,NCK1,NKD1,PPP1CB,PPP1CC,PPP1R12A,PPP1R2P3,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP4R3B,STRN 9.29 0.00260 0.0337170212765957 GO:0032432 actin filament bundle cellular_component 56 20 ABLIM3,ACTN1,CRYAB,DAAM1,FBLIM1,LCP1,MST1R,MYH10,MYH9,MYLK,NOX4,PDLIM2,PDLIM7,PTK2,PXN,SEPT7,SEPT9,SYNPO,VIL1,ZYX 10.84 0.00302 0.0380475757575758 GO:0034708 methyltransferase complex cellular_component 87 28 CBX5,EZH2,H2AFY,HDAC2,HDAC9,INO80C,KANSL1,KDM6A,KMT2A,KMT2D,KMT2E,METTL1,MGA,MTF2,NCOA6,OGT,PHF1,PHF20,PPP1CB,PPP1CC,PRMT1,PRMT5,RBBP4,RBBP7,RNF2,SNRPE,SNRPF,TRMT6 16.84 0.00304 0.0380475757575758 GO:0005743 mitochondrial inner membrane cellular_component 478 117 ABCB7,ABCB8,ACAD11,ACADVL,ACAT1,AIFM3,AK2,ALDH18A1,ALDH3A2,APOO,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,BOK,CDS2,CHCHD3,CKMT2,COA1,COQ4,COX5A,COX6A1,COX6B2,COX7A2L,CPOX,CPS1,CPT2,CRLS1,CSDE1,DAP3,GCAT,HSPD1,IMMP2L,LETM2,LETMD1,MCUR1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MT-ATP6,MTCH1,MT-CO1,MT-CO2,MT-CO3,MTG1,MTHFD2L,MT-ND4,MT-ND4L,MYOC,NDUFA3,NDUFA7,NDUFA9,NDUFAF6,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NME4,NNT,OCIAD2,OMA1,OPA1,PLA2G4B,PMPCB,PTCD3,RDH13,RHBDL3,SDHC,SDHD,SHMT2,SIRT5,SLC25A13,SLC25A18,SLC25A19,SLC25A27,SLC25A30,SLC25A31,SLC25A32,SLC25A36,SLC25A40,SLC25A44,SLC25A45,SLC25A48,SLC8B1,SPG7,STAR,SUCLG1,SURF1,TAZ,TIMM10B,TIMM23B,TIMM50,TMEM70,TST,TTC19,TYMS,UQCRB,UQCRC2,UQCRH 92.54 0.00305 0.0380475757575758 GO:0032154 cleavage furrow cellular_component 45 17 ECT2,MASTL,MYH10,MYH9,MYLK,NDE1,PLCD3,PLEKHG6,PLK4,PPP1CC,PSTPIP1,RACGAP1,RHOC,SEPT2,SEPT7,STAMBP,WDR73 8.71 0.00309 0.0380475757575758 GO:0097610 cell surface furrow cellular_component 45 17 ECT2,MASTL,MYH10,MYH9,MYLK,NDE1,PLCD3,PLEKHG6,PLK4,PPP1CC,PSTPIP1,RACGAP1,RHOC,SEPT2,SEPT7,STAMBP,WDR73 8.71 0.00309 0.0380475757575758 GO:0008540 proteasome regulatory particle, base sub... cellular_component 12 7 PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD2 2.32 0.00320 0.039008 GO:0044454 nuclear chromosome part cellular_component 467 114 ACTL6A,ATR,ATRX,AURKA,AURKB,BCAS2,BRCA1,BUB1B,BUD31,CBX5,CENPA,CENPC,CHRAC1,CSNK2A1,CTC1,DDB1,DNA2,EHMT2,ESR1,EZH2,FKBP6,GATAD2B,H2AFV,H2AFY,HAT1,HDAC1,HDAC2,HELB,HIST1H2BN,HIST2H2AC,HNRNPC,HNRNPK,HORMAD1,HUS1,INCENP,INO80,INO80C,INO80E,JUND,LIG4,MBD3,MCM2,MCMBP,MEF2A,MIS18BP1,MMS22L,MORF4L1,MSH5,NASP,NAT10,NCOA1,NCOR1,NCOR2,NFATC1,NPM2,NUCKS1,ORC4,PAWR,PHF12,PLCB1,PLRG1,PMS1,POLA1,POLA2,POLD3,POLD4,POT1,PPP1CB,PPP1CC,PURA,RAD51AP1,RBBP4,RBMX,RNF2,RNF212,RPA3,RXRA,SGO1,SIRT2,SIRT6,SMAD2,SMAD4,SMARCA2,SMARCA5,SMARCAD1,SMARCD2,SMARCE1,SMCHD1,SP1,SSB,STAG3,STAT6,SYCP3,TCF12,TCF7,TCP1,TERB2,TEX11,TFIP11,THOC1,THOC2,THOC7,TNKS,TP63,TTC21B,UBE2B,UCHL5,USP3,WAPL,WRN,XRCC3,XRCC5,ZNF385A,ZRANB3 90.41 0.00374 0.0451392079207921 GO:0043005 neuron projection cellular_component 952 217 AAK1,ABAT,ABI1,ADA,ADAM10,ADAM22,ADCY10,ADCY4,ADCYAP1,ADNP,ADORA1,AGO2,ANK2,ANK3,ANKS1B,APBB1,APBB2,ARF1,ARHGAP4,ARHGEF15,ARHGEF2,ASIC2,ATAT1,ATF4,ATP2B1,ATP2B4,ATP6V0D1,ATXN10,AURKA,AZIN2,BMPR1B,BOC,BPTF,BRAF,BRINP1,BRINP2,BSN,C4A,C4B,CACNA1A,CACNA1C,CALB1,CALM1,CAPRIN1,CASP8,CCDC120,CDC42,CDH13,CDH8,CHL1,CHRM2,CHRNA3,CHRNA7,CLN3,CLU,CNIH2,COBL,CPEB1,CPEB3,CPLX2,CPT1C,CRHBP,CRTAC1,CRYAB,CTNND1,CTTNBP2,CXADR,CYBB,CYFIP1,DAB2IP,DAG1,DCC,DCTN2,DICER1,DLG2,DLG3,DLGAP1,DNM3,DOCK7,DTNA,EEA1,EPB41L3,EPHA4,EPHB2,ERC2,ERO1A,EXOC4,FADD,FAM107A,FAM206A,FARP1,FAS,FBXO7,FEZ1,FEZ2,FKBP4,FUS,FXR1,GABBR1,GABRA5,GARS,GLRA3,GLRX2,GPM6A,GRIA4,GRID2IP,GRM5,GRM7,GSK3B,HDAC1,HDAC6,HNRNPA3,HOMER3,HTR2B,ITGA2,ITPR1,KCNA6,KCNAB2,KCNB1,KCNN2,KLHL20,KLHL24,LDLRAP1,LIMK1,LRRTM1,LYNX1,MAP1S,MAP2,MAP2K4,MAP3K12,MAPK8IP3,MINK1,MLPH,MME,MOB2,MPDZ,MTOR,MYH10,MYOC,NCOA1,NDRG2,NECTIN1,NF1,NGDN,NRSN1,NTRK2,OLFM1,OPA1,OPRK1,OPRM1,PAFAH1B1,PAK1,PALLD,PFN2,PICK1,PIN1,PKP4,PLCB4,PLK3,PPP1CC,PRKCZ,PSD3,PTBP2,PTEN,PTK2B,PTPN13,PTPRK,PTPRN,PURA,QDPR,RAB5A,RAP1A,RAP1GAP2,RAPGEF2,RASGRP2,RELN,RGS14,RNF6,ROBO1,ROBO3,RPLP0,RPS6KB1,RUFY3,SCN11A,SEPT5,SHANK2,SHTN1,SIRT2,SLC12A5,SLC1A3,SLC30A3,SLC38A2,SLC6A13,SNAP23,SNX14,SOS1,SPTBN1,SPTBN4,SRI,STAR,STMN4,STRN,SUMO1,SYNPO,SYNPR,SYT1,SYT5,TGFB1,THY1,TMEM57,TP63,TPGS1,UFL1,USP9X,WRN,YKT6,ZNF385A 184.3 0.00379 0.0452095145631068 GO:0098791 Golgi subcompartment cellular_component 290 75 AMPH,AP1G1,AP1M2,AP1S2,APH1A,ARF1,ARFRP1,ARL1,ATP2C1,ATP7B,ATP9B,ATXN2,AZIN2,BET1,BICD1,BIRC6,BOK,CD74,CDH1,CHID1,CLASP2,CLN3,CLTA,CLTC,CNST,COG2,COG5,CORO7,FNBP1,FNBP1L,FUT1,FUT8,FUT9,GALNT2,GCC2,GOLGA4,GOLGA7,GSAP,HACE1,HLA-DPB1,IGF2R,KIF13A,KLHL20,LGR5,M6PR,MYO18A,MYO1B,NAGPA,NCK1,NUCB1,OCRL,PLK3,RAB27B,RAB30,RIC1,SCAMP5,SCFD1,SCOC,SGMS1,SNX9,SOD3,SORL1,ST3GAL3,ST6GAL1,ST6GAL2,STX8,TMBIM4,TMED2,TMEM165,TOM1L1,TRIP10,USP6NL,VAMP4,VCPIP1,VPS54 56.14 0.00382 0.0452095145631068 GO:0000781 chromosome, telomeric region cellular_component 138 40 ATR,ATRX,CBX5,CTC1,DDB1,DMC1,DNA2,DOT1L,H2AFY,HAT1,LIG4,MCM2,NAT10,NSMCE1,NSMCE2,NSMCE4A,ORC4,POT1,PPP1CB,PPP1CC,PURA,RAD17,RIF1,RNF8,SIRT2,SIRT6,SMC6,SMCHD1,SMG6,SSB,TELO2,TERB2,TFIP11,THOC1,THOC2,THOC7,TNKS,WRN,XRCC3,XRCC5 26.72 0.00405 0.0474706730769231 GO:0071011 precatalytic spliceosome cellular_component 25 11 BCAS2,CRNKL1,PLRG1,PRPF38B,RBMX2,SF3B2,SF3B6,SNRNP40,SNRPE,SNU13,SON 4.84 0.00425 0.0493404761904762 GO:0001725 stress fiber cellular_component 50 18 ABLIM3,ACTN1,DAAM1,FBLIM1,LCP1,MST1R,MYH10,MYH9,MYLK,NOX4,PDLIM2,PDLIM7,PTK2,PXN,SEPT7,SEPT9,SYNPO,ZYX 9.68 0.00434 0.04991 GO:0005876 spindle microtubule cellular_component 54 19 AURKA,AURKB,BIRC3,BIRC7,CALM1,CDC27,CLASP1,CLASP2,CUL3,KNTC1,MAP9,NCOR1,NUSAP1,PAFAH1B1,POLB,PRC1,SPAG5,TBL1XR1,XIAP 10.45 0.00459 0.0522916822429907 GO:0098588 bounding membrane of organelle cellular_component 2354 503 ABCA2,ABCA5,ABCC6,ACAP1,ACAP2,ACSL1,AGK,AHNAK,AKAP1,AKTIP,ALDH3A2,ALG13,ALG9,AMBRA1,AMPH,ANKLE2,ANTXR1,ANXA2,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,APH1A,APOO,APPL1,APPL2,ARF1,ARFGAP2,ARFRP1,ARL1,ARL6,ARL8A,ASPSCR1,ATAD1,ATF2,ATG16L2,ATL2,ATP11B,ATP11C,ATP2A3,ATP2C1,ATP2C2,ATP5G3,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATRAID,ATXN3,AZIN2,B3GALNT2,BAX,BBS1,BBS2,BCL2,BET1,BLZF1,BOK,CALCOCO2,CALU,CAMK2A,CAMK2G,CASK,CASP4,CASP8,CCZ1,CCZ1B,CD14,CD163,CD1B,CD46,CD74,CD9,CDC42,CDHR1,CDKAL1,CDS2,CERS2,CHMP3,CHMP5,CHMP6,CHST1,CKAP4,CLCN3,CLN3,CLN8,CLTA,CLTC,CNGA1,CNIH1,CNIH2,COASY,COG2,COG5,COL6A1,COPA,COPB1,CORO7,CPT1C,CTDNEP1,CUL3,CUX1,CYBB,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAD1,DDOST,DEGS1,DHCR7,DMBT1,DMPK,DMXL2,DNAJB14,DNAJC1,DNAJC13,DNM1L,DPAGT1,DRAM2,DUOXA1,EEA1,EGF,EGFR,EHD2,EI24,ELOVL6,ELOVL7,EMC10,EMC2,ENTPD4,ENTPD6,EPHA4,ERAP2,ERC1,ERO1A,EVA1A,FADS1,FAF1,FAM21A,FAR1,FAXDC2,FCGR1B,FKBP3,FKBP4,FKBP6,FKBP8,FMN2,FNDC3A,FTCD,FUT1,FUT8,FUT9,GALNT11,GALNT14,GALNT16,GALNT2,GBA2,GBP5,GCNT3,GDAP2,GGA1,GGCX,GJB1,GNGT1,GNPAT,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GORASP2,GPR137B,GPR89B,GPSM1,GRIA4,HACD1,HACD3,HACE1,HGS,HGSNAT,HHATL,HLA-DMB,HLA-DPB1,HOOK1,HS6ST2,HSD17B3,HSD17B4,HSD17B6,HSD17B7,HSP90B1,HSPA8,ICA1,IGF2R,INPP5B,IRAK1,IRAK4,ITM2C,ITPR1,JKAMP,KDELR2,KDSR,KIF13A,KTN1,LAMP2,LAMTOR1,LAMTOR3,LBR,LDLRAP1,LETMD1,LFNG,LGR5,LITAF,LMF2,LNPEP,LPCAT3,LPCAT4,LPGAT1,LPIN1,LRAT,LRP6,LRPPRC,LRRC8B,LSS,LTV1,M6PR,MAN1C1,MAN2A1,MANEA,MANEAL,MAP1LC3B,MAP4K2,MAPK8IP3,MARCH5,MARCH6,MBTPS2,MCFD2,MDM2,MEST,MFF,MFN1,MFNG,MFSD2A,MGAT4A,MGAT4B,MGAT4C,MIA3,MITD1,MLXIP,MOXD1,MPHOSPH9,MPPE1,MR1,MSMO1,MSTO1,MTDH,MTOR,MTX1,MTX2,MTX3,MYO18A,MYO1B,MYOC,NAA60,NAGPA,NAPB,NAPEPLD,NAPG,NFE2L1,NOS3,NOX4,NOX5,NPLOC4,NR3C2,NRAS,NSDHL,NTRK2,NUCB1,OCRL,OPA1,ORMDL2,ORMDL3,OSBPL1A,OSBPL3,OSBPL5,OSBPL8,OSBPL9,OSTC,PAQR3,PCSK7,PCYOX1,PCYT1A,PDCD10,PDE6B,PECAM1,PEX11G,PEX16,PEX3,PEX5L,PGAP1,PGAP3,PICK1,PIGA,PIGN,PIGQ,PIGT,PIK3C3,PITPNB,PLA2G4B,PLA2G4C,PLD1,PLEKHM1,PLOD3,PLP2,POMT2,POR,PPP1CC,PPP6R3,PREB,PROM1,PTDSS1,PTPRN,PXYLP1,QTRT1,RAB11FIP2,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB30,RAB3GAP2,RAB5A,RAC2,RDH10,RHBDD1,RHBDD2,RHOT1,RIC1,RNF121,RNF13,RNF43,RP9,RPN2,RPS6KB1,RRAGB,RTN3,RTN4,RYR2,RYR3,SACM1L,SC5D,SCAMP5,SCAP,SCD5,SCFD1,SCOC,SCYL2,SDCBP,SEC11C,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SEPT2,SERINC3,SERP1,SFTPB,SGIP1,SGK1,SGMS1,SGPL1,SH3GL1,SHANK2,SIDT2,SLC11A2,SLC25A17,SLC25A46,SLC26A11,SLC28A3,SLC30A3,SLC30A5,SLC35A1,SLC35B1,SLC38A9,SLC39A13,SLC51A,SLC9A9,SNAPIN,SNX14,SNX16,SNX19,SNX2,SNX4,SPATA18,SPNS3,SPPL2A,SRI,SSR1,SSR2,SSR3,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,STAM,STEAP4,STIM2,STK25,STX5,STX8,STXBP2,SYN2,SYNE1,SYNPR,SYPL2,SYT1,SYT5,TAB2,TAB3,TAS2R4,TBC1D5,TBK1,TECR,TF,TGFA,TIGAR,TLR1,TLR7,TLR9,TM9SF2,TMBIM4,TMBIM6,TMC8,TMCO1,TMED2,TMEM106C,TMEM130,TMEM165,TMEM175,TMEM189,TMEM214,TMEM67,TMEM9,TMPO,TMX3,TNKS,TOM1L1,TOMM20,TOR1AIP2,TPST2,TRAM1,TRIQK,TTC9,TTC9C,TTYH1,UBA52,UBAC2,UBE2J2,UBXN4,UFL1,UGT1A1,UGT1A6,ULK2,UNC93B1,USP6NL,USP8,UVRAG,VAMP4,VDAC3,VPS11,VPS13C,VPS29,VPS36,VPS45,VPS4A,VPS54,VTA1,WDR11,WDR41,WDR44,WDR45B,YKT6,ZC3H12A,ZDHHC16 455.73 0.00470 0.0530490740740741 GO:0000922 spindle pole cellular_component 127 37 ANKRD53,AURKA,AURKB,BIRC6,CALM1,CDC6,CEP128,CEP44,CEP63,CEP89,CEP95,CSPP1,CUL3,DCTN1,DYNC1LI1,FAM110C,FAM175B,FBF1,FRY,KNTC1,NDC1,NDE1,NEK7,PKP4,PLEKHG6,POC1B,PRC1,RGS14,RMDN1,SGO1,SPAG5,SPDL1,TNKS,TOPBP1,TUBGCP5,VPS4A,WDR73 24.59 0.00506 0.0561848181818182 GO:0022625 cytosolic large ribosomal subunit cellular_component 66 22 COA1,MRPL1,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RSL24D1,SNU13 12.78 0.00507 0.0561848181818182 GO:0016580 Sin3 complex cellular_component 13 7 CSNK2A1,HDAC1,HDAC2,MORF4L1,NCOR1,PHF12,RBBP4 2.52 0.00579 0.0635856756756757 GO:0000120 RNA polymerase I transcription factor co... cellular_component 5 4 TAF1A,TAF1B,TAF1C,TAF1D 0.97 0.00593 0.0645416964285714 GO:0080008 Cul4-RING E3 ubiquitin ligase complex cellular_component 26 11 ARIH1,CRBN,CUL4B,DCAF11,DCAF13,DCAF17,DCAF6,DCAF8,DDB1,PLRG1,TRPC4AP 5.03 0.00610 0.0655479824561404 GO:0030175 filopodium cellular_component 91 28 ABI1,ANTXR1,CDC42,CXADR,DAG1,DNALI1,EPHA4,FAM65B,FARP1,FAT1,FGD4,GPM6A,ITGA6,ITGAV,LCP1,MYO10,MYO1B,MYO1G,NGDN,OSBPL3,RAPH1,RUFY3,SHTN1,SPATA13,TBC1D10C,TTYH1,TWF1,VIL1 17.62 0.00613 0.0655479824561404 GO:0035097 histone methyltransferase complex cellular_component 71 23 CBX5,EZH2,H2AFY,HDAC2,HDAC9,INO80C,KANSL1,KDM6A,KMT2A,KMT2D,KMT2E,MGA,MTF2,NCOA6,OGT,PHF1,PHF20,PPP1CB,PPP1CC,PRMT5,RBBP4,RBBP7,RNF2 13.75 0.00625 0.06625 GO:0005794 Golgi apparatus cellular_component 1444 316 ABCA5,ADAM10,AKTIP,AMPH,ANGPTL3,ANK3,AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,APH1A,APOO,ARF1,ARFGAP2,ARFRP1,ARHGAP4,ARHGEF2,ARL1,ASH1L,ATAT1,ATP11B,ATP2C1,ATP2C2,ATP7B,ATP9B,ATR,ATXN2,AZIN2,B3GALNT2,BET1,BICD1,BIRC6,BIRC7,BLZF1,BOK,BTN3A3,CALU,CAND1,CAPN8,CASC4,CCDC110,CCDC88A,CCDC91,CD14,CD44,CD74,CD79B,CDC42,CDC6,CDH1,CDK13,CEP57,CHID1,CHST1,CLASP1,CLASP2,CLCC1,CLCN3,CLEC18A,CLN3,CLTA,CLTC,CLU,CNIH1,CNIH2,CNST,COG2,COG5,COPA,COPB1,CORO7,CPQ,CRACR2A,CRHBP,CRYAB,CSDE1,CTNNA1,CUL3,CUX1,CWC22,CYBB,CYTH4,DBI,DNM1L,DNM3,DRAM2,EAPP,EGFR,EI24,ENTPD4,ENTPD6,EPHA4,ERC1,ESR1,FES,FEZ1,FGD3,FGD4,FGD6,FNBP1,FNBP1L,FNDC3A,FTCD,FUT1,FUT8,FUT9,GAK,GALNT11,GALNT14,GALNT16,GALNT2,GBA2,GBP5,GCC2,GCNT3,GDI2,GGA1,GLA,GNPTG,GOLGA4,GOLGA7,GOLT1A,GORASP1,GORASP2,GPC1,GPC3,GPR89B,GPSM1,GRHL1,GRINA,GSAP,GZF1,HACE1,HLA-DPB1,HS6ST2,HSPD1,ICA1,IGF2R,IL15,INPP5B,ITM2C,JAM3,KAT6A,KDELR2,KIF13A,KIFC3,KLHL20,KLK11,LAMTOR1,LARP7,LDLRAP1,LFNG,LGR5,LITAF,LRBA,LRP6,M6PR,MAN1C1,MAN2A1,MANEA,MANEAL,MAP4K2,MAP6,MAP6D1,MAPK8IP3,MBTPS2,MCFD2,METTL22,MFNG,MGAT4A,MGAT4B,MGAT4C,MIA3,MINK1,MPHOSPH9,MPPE1,MTOR,MTUS1,MUC15,MUC4,MYO18A,MYO1B,MYOC,NAA25,NAA60,NAGPA,NCK1,NDRG2,NOS3,NRAS,NUCB1,NUCB2,OCRL,OPRM1,OSBPL9,PAK1,PAQR3,PARP10,PAX2,PCSK5,PCSK7,PDCD10,PDE2A,PDE9A,PGAP3,PICK1,PITPNB,PKDCC,PLA2G5,PLD1,PLK3,PPHLN1,PPIL2,PPP6R3,PREB,PREPL,PRMT5,PSMG1,PTPRN,PWP1,PXYLP1,RAB1A,RAB27B,RAB2A,RAB2B,RAB30,RABGAP1L,RAPSN,RHBDD2,RIC1,RNF121,RNF13,RP2,RPGR,RRAGB,RTN3,SACM1L,SCAMP5,SCAP,SCFD1,SCOC,SCYL2,SEC14L1,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SERINC3,SGMS1,SGSM1,SLC26A11,SLC30A5,SLC35A1,SLC35B1,SLC39A13,SNAPIN,SNX9,SOD3,SORL1,SP3,SPPL2A,SPRY1,ST3GAL3,ST3GAL5,ST3GAL6,ST6GAL1,ST6GAL2,STEAP4,STK25,STMN4,STX5,STX8,SYNE1,SYT1,TCP1,TGFA,TGFB1,TLR1,TLR7,TLR9,TMBIM4,TMC8,TMCO1,TMED2,TMEM130,TMEM165,TMEM214,TNKS,TOM1L1,TOPBP1,TPST2,TRAPPC2B,TRIP10,UBAC1,UBXN2B,UNC93B1,USP32,USP33,USP6NL,USP8,VAMP4,VCPIP1,VPS45,VPS54,WDR44,WWOX,XRN1,YKT6,ZDHHC16,ZDHHC17,ZDHHC4,ZDHHC8,ZNF148 279.56 0.00677 0.0709520512820513 GO:0031902 late endosome membrane cellular_component 104 31 ABCA5,ANXA2,ANXA6,ARL8A,CHMP3,CHMP6,CLCN3,HGS,HLA-DMB,LAMP2,LAMTOR1,LAMTOR3,LTV1,MITD1,OSBPL9,PLD1,RAB27B,RNF13,SLC11A2,SLC30A3,SLC38A9,SLC9A9,SNX14,SNX16,SPPL2A,STX8,TMEM165,TMEM9,VPS11,VPS36,VPS4A 20.13 0.00681 0.0709520512820513 GO:0015934 large ribosomal subunit cellular_component 100 30 C12orf65,COA1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL41,MRPL51,MRPL52,NSUN4,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RSL24D1,SNU13 19.36 0.00695 0.0717970338983051 GO:0031984 organelle subcompartment cellular_component 306 77 AMPH,AP1G1,AP1M2,AP1S2,APH1A,ARF1,ARFRP1,ARL1,ATP2C1,ATP7B,ATP9B,ATXN2,AZIN2,BET1,BICD1,BIRC6,BOK,CD74,CDH1,CHID1,CLASP2,CLN3,CLTA,CLTC,CNST,COG2,COG5,CORO7,FNBP1,FNBP1L,FUT1,FUT8,FUT9,GALNT2,GCC2,GOLGA4,GOLGA7,GSAP,HACE1,HLA-DPB1,IGF2R,KIF13A,KLHL20,LGR5,M6PR,MYO18A,MYO1B,NAGPA,NCK1,NUCB1,OCRL,PLK3,RAB18,RAB27B,RAB30,REEP1,RIC1,SCAMP5,SCFD1,SCOC,SGMS1,SNX9,SOD3,SORL1,ST3GAL3,ST6GAL1,ST6GAL2,STX8,TMBIM4,TMED2,TMEM165,TOM1L1,TRIP10,USP6NL,VAMP4,VCPIP1,VPS54 59.24 0.00710 0.0724405737704918 GO:0000151 ubiquitin ligase complex cellular_component 288 73 ABTB1,ANAPC10,ANAPC4,ANAPC5,ANAPC7,ANKIB1,ARIH1,ASB15,ATG3,BRCA1,BTBD2,BTBD9,BUB1B,CACUL1,CAND1,CDC23,CDC27,CRBN,CUL1,CUL3,CUL4B,CUL9,DCAF11,DCAF13,DCAF17,DCAF6,DCAF8,DCUN1D4,DDB1,DNAJA1,DYRK2,FBXL3,FBXL4,FBXO11,FBXO24,FBXO7,FBXW11,FZR1,HSPA8,IPP,KBTBD6,KCTD10,KLHL13,KLHL20,KLHL24,KLHL3,KLHL40,KLHL5,KLHL7,MARCH6,MED21,MED24,MED30,MED31,OTULIN,PHC3,PLRG1,RBCK1,RCHY1,RNF14,RNF2,RNF216,RNF4,RNF8,TCEB1,TRPC4AP,UBE2B,UBE2E1,UBE2J2,UBE2V1,UBE4A,USP33,WWP1 55.76 0.00717 0.0724405737704918 GO:0044545 NSL complex cellular_component 3 3 KANSL1,KANSL1L,KANSL2 0.58 0.00725 0.0724405737704918 GO:0097149 centralspindlin complex cellular_component 3 3 ECT2,KIF23,RACGAP1 0.58 0.00725 0.0724405737704918 GO:0042641 actomyosin cellular_component 60 20 ABLIM3,ACTN1,DAAM1,FBLIM1,KAT2B,LCP1,MST1R,MYH10,MYH9,MYLK,MYO18A,NOX4,PDLIM2,PDLIM7,PTK2,PXN,SEPT7,SEPT9,SYNPO,ZYX 11.62 0.00734 0.0727435772357723 GO:0005732 small nucleolar ribonucleoprotein comple... cellular_component 20 9 FBL,LSM6,MPHOSPH10,NOP10,NOP56,NOP58,SNRNP40,SNRPF,SNU13 3.87 0.00799 0.0785468548387097 GO:0044450 microtubule organizing center part cellular_component 152 42 AURKA,BRCA1,CCDC14,CCDC146,CCDC78,CCDC92,CENPJ,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP63,CEP89,CFAP20,CLASP1,DCTN1,FBF1,FTCD,HAP1,IQCB1,KIAA0753,LRRCC1,MDM1,MKS1,MPHOSPH9,OFD1,PAX2,PCM1,PLK4,POC1B,POC5,RP2,SASS6,SDCCAG8,SIRT2,SPAG5,SSX2IP,TCP1,TNKS,TUBGCP5 29.43 0.00819 0.07986888 GO:0061695 transferase complex, transferring phosph... cellular_component 236 61 BCCIP,CCNC,CCNL2,CCNT1,CCNT2,CDK12,CDK13,CDK7,CHD6,CHRAC1,CHUK,CPSF3L,CRCP,CTR9,DNA2,ERC1,FAM58A,GTF2H2,GTF2H3,GTF2H5,HELB,HSPD1,INTS10,INTS12,INTS6,INTS8,LEO1,MED14,MED31,MNAT1,MTOR,PAPD4,PFKFB1,PHKA1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,POLA1,POLA2,POLD3,POLD4,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POLR3C,POLR3F,PRKAR2A,RECQL5,RPRD2,SHFM1,TAF2,TBPL1,TGFBR1,UVRAG 45.69 0.00853 0.0824504724409449 GO:0030424 axon cellular_component 377 92 AAK1,ADAM22,ADCY10,ADCYAP1,ADNP,ADORA1,ANK3,APBB1,ATAT1,ATP6V0D1,AURKA,AZIN2,BOC,BSN,C4A,C4B,CALB1,CDH8,CHRM2,CHRNA7,COBL,CPLX2,CPT1C,CRHBP,CRYAB,DAB2IP,DAG1,DCC,DICER1,DLG2,DNM3,DOCK7,DTNA,EEA1,EPB41L3,EPHA4,EPHB2,FEZ1,FEZ2,FKBP4,FXR1,GARS,GPM6A,GRM7,HDAC6,ITGA2,KCNA6,KCNAB2,KCNB1,KLHL20,KLHL24,LDLRAP1,LRRTM1,MAP2K4,MAP3K12,MAPK8IP3,MINK1,MME,MYH10,MYOC,NECTIN1,NF1,NGDN,NTRK2,OLFM1,OPRK1,PAK1,PALLD,PFN2,PRKCZ,PTK2B,PTPRK,PTPRN,RAB5A,RNF6,ROBO1,ROBO3,RUFY3,SCN11A,SEPT5,SHANK2,SHTN1,SIRT2,SLC38A2,SPTBN1,SPTBN4,SRI,STMN4,SYT1,TGFB1,TMEM57,TPGS1 72.99 0.00859 0.0824504724409449 GO:0005814 centriole cellular_component 110 32 AURKA,CCDC146,CCDC78,CCDC92,CENPJ,CEP128,CEP135,CEP164,CEP170,CEP192,CEP290,CEP63,CEP89,CFAP20,DCTN1,FBF1,FTCD,HAP1,IQCB1,LRRCC1,MDM1,MKS1,MPHOSPH9,OFD1,PCM1,PLK4,POC1B,POC5,RP2,SASS6,SDCCAG8,SIRT2 21.3 0.00890 0.084111 GO:0010008 endosome membrane cellular_component 396 96 ABCA2,ABCA5,ACAP1,ACAP2,ANTXR1,ANXA2,ANXA6,AP1G2,APPL1,APPL2,ARL8A,ATP11B,ATP6V0A4,ATP6V0D1,BOK,CD14,CD1B,CHMP3,CHMP5,CHMP6,CLCN3,CLTA,CLTC,DNAJC13,EEA1,EGFR,EHD2,EPHA4,FAM21A,FCGR1B,GGA1,HGS,HLA-DMB,HLA-DPB1,HSD17B6,INPP5B,IRAK1,IRAK4,KIF13A,LAMP2,LAMTOR1,LAMTOR3,LRP6,LTV1,MITD1,MYO1B,NTRK2,OCRL,OSBPL9,PLA2G4B,PLD1,PLEKHM1,RAB11FIP2,RAB22A,RAB27B,RAB5A,RNF13,SCAMP5,SCYL2,SH3GL1,SLC11A2,SLC30A3,SLC38A9,SLC9A9,SNX14,SNX16,SNX19,SNX2,SNX4,SPPL2A,STAM,STX8,SYT5,TAB2,TAB3,TBC1D5,TBK1,TF,TLR7,TLR9,TM9SF2,TMEM165,TMEM175,TMEM9,TOM1L1,UBA52,USP8,VPS11,VPS29,VPS36,VPS45,VPS4A,VTA1,WDR44,ZFYVE16,ZNRF2 76.66 0.00893 0.084111 GO:0005657 replication fork cellular_component 61 20 BCAS2,CHRAC1,HELB,MMS22L,PLRG1,POLA1,POLA2,POLD3,POLD4,PURA,RAD18,RAD51C,RFC2,RFC4,RPA3,SMARCA5,SMARCAD1,UBE2B,XRCC3,ZRANB3 11.81 0.00897 0.084111 GO:0005858 axonemal dynein complex cellular_component 14 7 CCDC114,DNAH17,DNAH2,DNAH3,DNAI1,DNAI2,DNALI1 2.71 0.00965 0.0897965648854962 GO:0035861 site of double-strand break cellular_component 31 12 ATF2,C9orf142,HELB,HUS1,PHF1,RAD18,RFWD3,RNF138,RNF8,SLF1,SMARCAD1,SMC6 6 0.00976 0.0901321212121212 GO:0043220 Schmidt-Lanterman incisure cellular_component 11 6 AKR1B1,ANXA2,JAM3,MPDZ,PTEN,SIRT2 2.13 0.00988 0.0905542857142857 GO:0045178 basal part of cell cellular_component 46 16 ADCY10,ANK3,C5AR2,CLASP1,CLASP2,CLDN11,CLDN4,DOCK7,HOMER3,ITGA2,ITGA6,LDLRAP1,P2RY12,PHLDB1,SLC11A2,TF 8.91 0.01006 0.0915159701492537 GO:0005770 late endosome cellular_component 203 53 ABCA5,ANKRD13B,ANXA2,ANXA6,ARF1,ARL8A,ATP7B,CD74,CHID1,CHMP3,CHMP6,CLCN3,CLN3,CRHBP,DYSF,HDAC6,HGS,HLA-DMB,HSPA8,IGF2R,LAMP2,LAMTOR1,LAMTOR3,LRAT,LTV1,M6PR,MITD1,OSBPL1A,OSBPL9,PIK3C3,PLD1,RAB22A,RAB27B,RAP1A,RAPGEF2,RNF13,SFTPB,SLC11A2,SLC30A3,SLC38A9,SLC9A9,SNX14,SNX16,SPPL2A,STX8,TF,TMEM165,TMEM9,UVRAG,VPS11,VPS29,VPS36,VPS4A 39.3 0.01104 0.0996871111111111 GO:0000794 condensed nuclear chromosome cellular_component 87 26 ADD3,AURKA,AURKB,BRCA1,BRD4,BUB1B,CENPA,CENPC,DMC1,FKBP6,HORMAD1,HUS1,INCENP,LRPPRC,MIS18BP1,MSH5,PMS1,RAD51C,RNF212,SGO1,SMC1A,STAG3,SYCP3,TEX11,TOPBP1,WAPL 16.84 0.01204 0.107752481751825 GO:0044440 endosomal part cellular_component 419 100 ABCA2,ABCA5,ACAP1,ACAP2,ANTXR1,ANXA2,ANXA6,AP1G2,APPL1,APPL2,ARL8A,ATP11B,ATP6V0A4,ATP6V0D1,BOK,CD14,CD1B,CHMP3,CHMP5,CHMP6,CLCN3,CLTA,CLTC,DNAJC13,EEA1,EGFR,EHD2,EPHA4,FAM21A,FCGR1B,GGA1,HGS,HLA-DMB,HLA-DPB1,HSD17B6,INPP5B,IRAK1,IRAK4,KIF13A,LAMP2,LAMTOR1,LAMTOR3,LNPEP,LRP6,LTV1,MITD1,MYO1B,NTRK2,OCRL,OSBPL9,PLA2G4B,PLD1,PLEKHM1,PRLR,RAB11FIP2,RAB22A,RAB27B,RAB5A,RNF13,RRAGB,SCAMP5,SCYL2,SH3GL1,SLC11A2,SLC30A3,SLC38A9,SLC9A9,SNX14,SNX16,SNX19,SNX2,SNX4,SPPL2A,STAM,STX8,SYT5,TAB2,TAB3,TBC1D5,TBK1,TF,TLR7,TLR9,TM9SF2,TMEM165,TMEM175,TMEM9,TOM1L1,UBA52,USP8,VPS11,VPS29,VPS36,VPS45,VPS4A,VPS8,VTA1,WDR44,ZFYVE16,ZNRF2 81.12 0.01211 0.107752481751825 GO:0032588 trans-Golgi network membrane cellular_component 79 24 AP1G1,AP1M2,AP1S2,ARFRP1,ARL1,ATP7B,BOK,CD74,CLTA,CLTC,COG2,COG5,HLA-DPB1,IGF2R,KIF13A,LGR5,M6PR,MYO1B,RIC1,SCAMP5,TMEM165,USP6NL,VAMP4,VPS54 15.29 0.01254 0.11077 GO:0098805 whole membrane cellular_component 1989 423 AAK1,ABCA2,ABCA5,ABCB1,ABCB4,ABCC6,ABI1,ACAP1,ACAP2,ACSL1,ADGRG2,ADORA1,AGK,AHNAK,AKAP1,AKR1A1,AKTIP,ALDH3A2,AMBRA1,AMPH,ANK2,ANK3,ANKS1B,ANTXR1,ANXA2,ANXA6,ANXA7,AP1G1,AP1G2,AP1M2,AP1S2,APBB1,APPL1,APPL2,ARF1,ARHGEF2,ARL6,ARL8A,ARPC1A,ATAD1,ATAT1,ATF2,ATF4,ATG16L2,ATP11B,ATP11C,ATP1B1,ATP2B1,ATP2B4,ATP5G3,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATRAID,BAX,BBS1,BBS2,BCL2,BIRC3,BOK,BTK,C1QTNF5,C2CD5,C5AR2,CACNB3,CADPS2,CALCOCO2,CAMK2A,CAMK2G,CASK,CASP8,CCZ1,CCZ1B,CD14,CD163,CD1B,CD46,CD74,CD9,CDH1,CDH13,CDHR1,CEACAM5,CFAP126,CFLAR,CHMP3,CHMP5,CHMP6,CHRM2,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CLASP2,CLCN3,CLDN4,CLDN7,CLN3,CLTA,CLTC,CNGA1,CNIH1,CNIH2,CNTN1,COASY,COL6A1,COPA,COPB1,CPEB1,CPT1C,CRYAB,CTNNA1,CXADR,CYBB,CYP4F12,DAG1,DAPK3,DDR2,DHCR7,DLG2,DLG3,DLGAP1,DMBT1,DMPK,DMXL2,DNAJC13,DNM1L,DRAM2,DSG2,EEA1,EGF,EGFR,EHD2,EPB41L3,EPHA4,EPN3,EPS8L1,ERC1,ERC2,EVA1A,FADD,FAM21A,FAM65B,FAR1,FAS,FCGR1B,FCHO1,FCHO2,FERMT1,FNBP1,FRMPD2,FZD6,GABBR1,GABRA5,GABRE,GABRG3,GABRP,GDAP2,GGA1,GIF,GLRA3,GNA12,GNGT1,GNPAT,GPC1,GPIHBP1,GPR137B,GPRC5B,GRIA4,GRID1,GRID2IP,GRM7,GRM8,HDAC6,HGS,HGSNAT,HLA-DMB,HLA-DPB1,HOMER3,HOOK1,HSD17B4,HSD17B6,HSPA8,HSPD1,ICA1,IGF2R,IGFBP2,INPP5B,IRAK1,IRAK4,ITGA6,ITGAV,ITM2C,ITPR1,KANK1,KCNB1,KCNMA1,KIF13A,KNCN,KRAS,LAMP2,LAMTOR1,LAMTOR3,LAT,LCP1,LDLRAP1,LETMD1,LITAF,LNPEP,LPIN1,LRP6,LRPPRC,LRRTM1,LRRTM3,LTV1,M6PR,MAL2,MAP1LC3B,MAP4K2,MAPK8IP3,MARCH5,MCFD2,MDM2,MEGF10,MEGF11,MFF,MFN1,MINK1,MIP,MITD1,MLXIP,MPDZ,MSTO1,MTDH,MTOR,MTX1,MTX2,MTX3,MYO10,MYO1B,MYOC,NAPB,NAPEPLD,NAPG,NECTIN1,NOS3,NOX1,NOX4,NRXN1,NTRK2,OCRL,OPA1,OPRM1,OSBPL1A,OSBPL9,OSMR,P2RY12,PAK1,PCYOX1,PDE2A,PDE4D,PDE6B,PDE9A,PDGFRB,PDZK1,PECAM1,PEX11G,PEX16,PEX3,PEX5L,PICK1,PIK3C3,PIP5K1A,PIP5K1C,PLA2G4B,PLD1,PLEK2,PLEKHM1,PPP1CC,PRKCZ,PROM1,PSD3,PTEN,PTH1R,PTK2,PTK2B,PTPRN,QTRT1,RAB11FIP2,RAB22A,RAB27B,RAB2A,RAB5A,RAC2,RAP1B,RAPGEF2,RAPSN,RASGRP2,REPS1,RGS14,RHOT1,RIMS1,RNF13,RPN2,RPS6KB1,RRAGB,RTN4RL2,SCAMP5,SCAP,SCNN1B,SCYL2,SDCBP,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEPT2,SEPT7,SGIP1,SH3GL1,SH3YL1,SHANK2,SIDT2,SLC11A2,SLC22A11,SLC22A7,SLC25A17,SLC25A46,SLC26A11,SLC2A5,SLC2A9,SLC30A3,SLC30A5,SLC34A1,SLC38A9,SLC4A2,SLC5A1,SLC6A19,SLC9A9,SNAP91,SNAPIN,SNX14,SNX16,SNX19,SNX2,SNX4,SORBS2,SPATA13,SPATA18,SPNS3,SPPL2A,SPTBN1,SRI,STAM,STAT6,STRN,STX5,STX8,STXBP2,SYN2,SYNE1,SYNPO,SYNPR,SYPL2,SYT1,SYT5,TAB2,TAB3,TAS2R4,TBC1D10C,TBC1D5,TBK1,TF,TFRC,TGFA,TGFBR1,THY1,TIGAR,TLN1,TLR1,TLR7,TLR9,TM9SF2,TMED2,TMEM165,TMEM175,TMEM67,TMEM9,TMX3,TNK2,TOM1L1,TOMM20,TRADD,TRPM6,TTYH1,TWF1,UBA52,ULK2,UPK1B,USH2A,USP8,UVRAG,VDAC3,VPS11,VPS13C,VPS29,VPS36,VPS45,VPS4A,VTA1,WDR11,WDR41,WDR44,WDR45B,XPO1,ZAP70,ZC4H2,ZDHHC17,ZFYVE16,ZNRF2 385.07 0.01266 0.110929 GO:0000932 cytoplasmic mRNA processing body cellular_component 75 23 AGO1,AGO2,APOBEC3F,BTBD2,CAPRIN1,CNOT2,CNOT7,CPEB1,DDX6,EDC3,EIF4E,LIMD1,LSM6,PAN3,PNRC2,POLR2G,PSMA2,PSMA4,PSMA6,PSMC2,RBPMS,TRIM5,ZC3H12A 14.52 0.01274 0.110929 GO:0030425 dendrite cellular_component 520 121 ABI1,ADA,ADAM10,ADCY10,ADCY4,ADNP,ADORA1,AGO2,ANK3,ANKS1B,APBB1,ARF1,ARHGEF15,ARHGEF2,ASIC2,ATP2B1,ATXN10,AZIN2,BMPR1B,BPTF,BRINP1,BRINP2,BSN,C4A,C4B,CACNA1A,CACNA1C,CALB1,CAPRIN1,CHL1,CHRM2,CHRNA3,CLU,CNIH2,COBL,CPEB1,CPEB3,CPLX2,CPT1C,CRHBP,CRYAB,CTNND1,CTTNBP2,CYBB,DAB2IP,DICER1,DLG2,DLG3,DLGAP1,DNM3,EPHA4,EPHB2,ERO1A,FAM206A,FARP1,FEZ1,FUS,FXR1,GABBR1,GABRA5,GLRA3,GLRX2,GPM6A,GRIA4,GRID2IP,GRM5,GRM7,GSK3B,HDAC6,HOMER3,HTR2B,ITPR1,KCNAB2,KCNB1,KCNN2,KLHL20,LYNX1,MAP1S,MAP2K4,MAPK8IP3,MINK1,MLPH,MME,MPDZ,MTOR,MYH10,NF1,NGDN,OPA1,OPRK1,OPRM1,PAK1,PICK1,PKP4,PLCB4,PLK3,PPP1CC,PSD3,PTEN,PTK2B,PTPRK,PURA,RAB5A,RELN,RGS14,RPLP0,RUFY3,SHANK2,SLC12A5,SLC38A2,SNX14,SOS1,SRI,STRN,SUMO1,SYNPO,THY1,TP63,TPGS1,YKT6,ZNF385A 100.67 0.01409 0.121813546099291 GO:0043596 nuclear replication fork cellular_component 40 14 BCAS2,CHRAC1,HELB,MMS22L,PLRG1,POLA1,POLA2,POLD3,POLD4,PURA,RPA3,SMARCA5,SMARCAD1,ZRANB3 7.74 0.01467 0.124535675675676 GO:0005643 nuclear pore cellular_component 80 24 AAAS,AGFG1,AHCTF1,ENY2,MVP,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,SENP2,SUMO1,TNKS,XPO7,XPOT 15.49 0.01470 0.124535675675676 GO:0043235 receptor complex cellular_component 297 73 AHR,AIP,BMPR1B,CD14,CD247,CD3G,CD44,CD6,CD74,CD79B,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHUK,CNIH2,CPT1C,DDR1,DIABLO,DLG2,DLG3,EGF,EGFR,FGFR1,GABBR1,GPR160,GRIA4,GRM7,HSPD1,IGF1R,IL4R,IRAK1,ITGA2,ITGA6,ITGA7,ITGAL,ITGAV,ITGB4,ITGB6,ITGB8,KLRD1,LOXL4,LRP6,MTTP,MYH9,NR3C2,NRP2,NTRK2,NTRK3,OSMR,PEX5L,PIGR,PLXNA1,PLXNB1,PLXNC1,PLXND1,PTH1R,PTK2B,PTPN6,PTPRA,RXRA,SACM1L,SDCBP,SHANK2,TGFBR1,TLR1,TLR7,TRADD,TRIP6,TRPC1,TSHR,TSPAN32,ZAP70 57.5 0.01496 0.124535675675676 GO:0031428 box C/D snoRNP complex cellular_component 6 4 FBL,NOP56,NOP58,SNU13 1.16 0.01505 0.124535675675676 GO:0033588 Elongator holoenzyme complex cellular_component 6 4 ELP2,ELP4,ELP5,ELP6 1.16 0.01505 0.124535675675676 GO:0042382 paraspeckles cellular_component 6 4 CPSF6,HNRNPM,NUDT21,SFPQ 1.16 0.01505 0.124535675675676 GO:0016514 SWI/SNF complex cellular_component 15 7 ACTL6A,ARID1B,NCR1,SMARCA2,SMARCD1,SMARCD2,SMARCE1 2.9 0.01512 0.124535675675676 GO:0005768 endosome cellular_component 784 176 ABCA2,ABCA5,ACAP1,ACAP2,ACE,ANGPTL3,ANKRD13B,ANTXR1,ANXA2,ANXA6,AP1G1,AP1G2,APPL1,APPL2,ARF1,ARL8A,ATP11B,ATP11C,ATP6V0A4,ATP6V0D1,ATP7B,ATP9B,AVL9,BIRC6,BOK,C16orf62,CARMIL2,CCDC120,CD14,CD1B,CD74,CDH1,CHID1,CHMP3,CHMP5,CHMP6,CLCN3,CLEC18A,CLIP1,CLN3,CLTA,CLTC,CRHBP,DNAJC13,DSCR3,DYSF,EEA1,EGFR,EHD2,EPHA4,EXPH5,FAM21A,FCGR1B,FCHSD1,FRS2,GCGR,GGA1,GIF,GPC1,HAVCR2,HDAC6,HGS,HLA-DMB,HLA-DPB1,HSD17B6,HSPA8,HSPD1,IGF2R,IL15,INPP5B,IRAK1,IRAK4,KIF13A,LAMP2,LAMTOR1,LAMTOR3,LDLRAP1,LNPEP,LRAT,LRP6,LTV1,M6PR,MGRN1,MITD1,MYO1B,NISCH,NOX1,NTRK2,NUCB1,OCIAD2,OCRL,OSBPL1A,OSBPL9,PAK3,PANK1,PIK3C3,PLA2G4B,PLD1,PLEKHM1,PRKCZ,PRLR,PTP4A2,PTPRN,RAB11FIP2,RAB1A,RAB22A,RAB27B,RAB5A,RABEP1,RABGAP1L,RAP1A,RAPGEF2,RNF13,RNF32,RPS6KC1,RRAGB,SCAMP5,SCOC,SCYL2,SDCCAG3,SFTPB,SH3GL1,SLC11A2,SLC30A3,SLC34A1,SLC38A9,SLC9A9,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SORL1,SPPL2A,STAM,STAMBP,STEAP1B,STEAP4,STX8,SYT5,TAB2,TAB3,TBC1D5,TBK1,TF,TFRC,TGFBR1,TLR7,TLR9,TM9SF2,TMEM165,TMEM175,TMEM9,TNK2,TOM1L1,TRAK1,UBA52,UNC93B1,USP8,UVRAG,VAMP4,VPS11,VPS29,VPS36,VPS45,VPS4A,VPS8,VTA1,WDR44,WDR72,YKT6,ZFYVE16,ZFYVE21,ZNRF2 151.78 0.01528 0.125008859060403 GO:0005868 cytoplasmic dynein complex cellular_component 29 11 CCDC114,DCTN4,DNAH17,DNAH2,DNAH3,DNAI1,DNAI2,DNALI1,DYNC1I2,DYNC1LI1,SNX4 5.61 0.01552 0.126125866666667 GO:0005938 cell cortex cellular_component 234 59 ACTR2,ADD3,AKAP12,ANLN,ANXA2,BIN2,BSN,C2CD5,CDH1,CLASP1,CLASP2,COBL,CTTNBP2,EXOC1,EXOC3L2,EXOC4,EXOC6,EXOC6B,FAM110C,FBLIM1,FMN2,FNBP1,FNBP1L,FRY,FRYL,GRM7,GSN,KNCN,LAMC2,LANCL2,LLGL2,MAEA,MELK,MKLN1,MLPH,MYH10,MYH9,MYO10,PAFAH1B1,PDLIM2,PHLDB1,PLA2G4C,PRKCZ,PTK2,PTK2B,PXN,RAI14,RALB,RASAL3,RIC8B,SEPT2,SEPT5,SEPT7,SEPT9,SPTB,SPTBN1,SPTBN4,TRIP10,WDR43 45.3 0.01605 0.129419805194805 GO:0005680 anaphase-promoting complex cellular_component 22 9 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BUB1B,CACUL1,CDC23,CDC27,FZR1 4.26 0.01635 0.129419805194805 GO:0046540 U4/U6 x U5 tri-snRNP complex cellular_component 22 9 CD2BP2,LSM5,LSM6,LSM8,PRPF18,SART3,SNRPE,SNU13,TXNL4B 4.26 0.01635 0.129419805194805 GO:0097526 spliceosomal tri-snRNP complex cellular_component 22 9 CD2BP2,LSM5,LSM6,LSM8,PRPF18,SART3,SNRPE,SNU13,TXNL4B 4.26 0.01635 0.129419805194805 GO:0042405 nuclear inclusion body cellular_component 12 6 ATXN3,NUP98,PABPN1,RAD18,RANBP2,SLF1 2.32 0.01656 0.130236387096774 GO:0030127 COPII vesicle coat cellular_component 9 5 SEC23B,SEC24A,SEC24B,SEC24D,SEC31A 1.74 0.01704 0.133152307692308 GO:0005875 microtubule associated complex cellular_component 146 39 AURKA,AURKB,CCDC114,CLIP2,DCTN1,DCTN2,DCTN4,DCTN6,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNALI1,DYNC1I2,DYNC1LI1,EML2,FNTA,HAUS3,HDAC6,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,MAP2,NDE1,PAFAH1B1,PXN,RANBP2,SHTN1,SNX4,WDR43 28.27 0.01839 0.142786050955414 GO:0043601 nuclear replisome cellular_component 26 10 BCAS2,CHRAC1,HELB,PLRG1,POLA1,POLA2,POLD3,POLD4,PURA,RPA3 5.03 0.01862 0.143656835443038 GO:0044452 nucleolar part cellular_component 61 19 FBL,HEATR1,MPHOSPH10,NOP10,NOP56,NOP58,POLR1D,POLR2E,POLR2H,POLR2K,SNU13,SUMO1,TAF1A,TAF1B,TAF1C,TAF1D,UTP4,WDR12,WDR43 11.81 0.01888 0.144746666666667 GO:0005774 vacuolar membrane cellular_component 328 79 ABCA2,ABCA5,AHNAK,AKTIP,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ATG16L2,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,CALCOCO2,CCZ1,CCZ1B,CD1B,CD74,CLN3,CLTA,CLTC,COL6A1,DNAJC13,DRAM2,EGF,EVA1A,GDAP2,GPR137B,HGSNAT,HLA-DMB,HLA-DPB1,HOOK1,HSPA8,IGF2R,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LITAF,LNPEP,LTV1,M6PR,MAP1LC3B,MTOR,NAPB,NAPG,OSBPL1A,PCYOX1,PLD1,PLEKHM1,RAB2A,RNF13,RPN2,RRAGB,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAPIN,SNX14,SPNS3,SPPL2A,STX8,TLR7,TLR9,TMEM165,TMEM175,TMEM9,UBA52,UVRAG,VPS11,VPS4A,WDR11,WDR41,ZNRF2 63.5 0.01909 0.1454419375 GO:0000159 protein phosphatase type 2A complex cellular_component 19 8 NKD1,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,STRN 3.68 0.01925 0.14575 GO:0005905 coated pit cellular_component 70 21 AAK1,AP1S2,ATAT1,CLTA,CLTC,DNM1L,EGFR,EPN3,FCHO1,FCHO2,FNBP1,HSPD1,LDLRAP1,OCRL,REPS1,SGIP1,SNAP91,TBC1D5,TF,TFRC,TNK2 13.55 0.02154 0.162081851851852 GO:0035098 ESC/E(Z) complex cellular_component 16 7 EZH2,H2AFY,HDAC2,MTF2,PHF1,RBBP4,RBBP7 3.1 0.02246 0.165931757575758 GO:0044295 axonal growth cone cellular_component 16 7 BOC,COBL,EPHA4,FKBP4,GPM6A,OLFM1,SHTN1 3.1 0.02246 0.165931757575758 GO:0070822 Sin3-type complex cellular_component 16 7 CSNK2A1,HDAC1,HDAC2,MORF4L1,NCOR1,PHF12,RBBP4 3.1 0.02246 0.165931757575758 GO:0031248 protein acetyltransferase complex cellular_component 100 28 ACTL6A,ATXN7,DR1,ELP2,ELP4,ENY2,JADE1,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,MEAF6,MORF4L1,NAA10,NAA16,NAA20,NAA25,OGT,PHF20,SUPT20H,TAF2,UBAP2L,USP34,WDR75,YEATS4,ZZZ3 19.36 0.02288 0.167010299401198 GO:1902493 acetyltransferase complex cellular_component 100 28 ACTL6A,ATXN7,DR1,ELP2,ELP4,ENY2,JADE1,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,MEAF6,MORF4L1,NAA10,NAA16,NAA20,NAA25,OGT,PHF20,SUPT20H,TAF2,UBAP2L,USP34,WDR75,YEATS4,ZZZ3 19.36 0.02288 0.167010299401198 GO:0005840 ribosome cellular_component 234 58 C12orf65,COA1,DAP3,DNAJC21,EIF2AK2,HSPA14,MCTS1,MRPL1,MRPL13,MRPL19,MRPL32,MRPL35,MRPL41,MRPL42,MRPL48,MRPL50,MRPL51,MRPL52,MRPS10,MRPS11,MRPS18C,MRPS23,MRPS30,MRPS35,MRPS6,MTG1,NAA10,NCK1,NDUFA7,NSUN4,PRMT3,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RPS6KL1,RSL24D1,SERP1,SF1,SNU13,UBA52 45.3 0.02349 0.170442321428571 GO:0046930 pore complex cellular_component 96 27 AAAS,AGFG1,AHCTF1,BAX,BCL2,ENY2,MVP,NDC1,NUP107,NUP155,NUP205,NUP35,NUP37,NUP50,NUP54,NUP58,NUP98,NUPL2,RAE1,RANBP2,SEH1L,SENP2,SUMO1,TNKS,VDAC3,XPO7,XPOT 18.59 0.02376 0.171381301775148 GO:0005789 endoplasmic reticulum membrane cellular_component 984 215 ABCC6,ACSL1,ALDH3A2,ALG13,ALG9,ANKLE2,ANXA7,APH1A,APOO,ATL2,ATP11C,ATP2A3,ATXN3,BAX,BCL2,BET1,BOK,CALU,CAMK2G,CASP4,CD74,CDC42,CDKAL1,CDS2,CERS2,CKAP4,CLN3,CLN8,CNIH1,CNIH2,COPA,COPB1,CPT1C,CTDNEP1,CYBB,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,DAD1,DDOST,DEGS1,DHCR7,DMPK,DNAJB14,DNAJC1,DNM1L,DPAGT1,DUOXA1,EGFR,EI24,ELOVL6,ELOVL7,EMC10,EMC2,ERAP2,ERO1A,EVA1A,FADS1,FAF1,FAXDC2,FKBP3,FKBP4,FKBP6,FKBP8,FMN2,FTCD,GALNT2,GBA2,GGCX,GJB1,GPSM1,HACD1,HACD3,HHATL,HLA-DPB1,HSD17B3,HSD17B7,HSP90B1,ITPR1,JKAMP,KDELR2,KDSR,KTN1,LBR,LMF2,LPCAT3,LPCAT4,LPGAT1,LPIN1,LRAT,LRRC8B,LSS,MARCH5,MARCH6,MCFD2,MEST,MFSD2A,MIA3,MOXD1,MR1,MSMO1,MTDH,MTOR,NFE2L1,NOX4,NOX5,NPLOC4,NR3C2,NSDHL,ORMDL2,ORMDL3,OSBPL3,OSBPL5,OSBPL8,OSTC,PCYT1A,PEX16,PGAP1,PGAP3,PIGA,PIGN,PIGQ,PIGT,PITPNB,PLA2G4C,PLD1,PLOD3,PLP2,POMT2,POR,PREB,PTDSS1,RAB18,RAB1A,RAB2A,RAB2B,RAB3GAP2,RDH10,RHBDD1,RNF121,RNF13,RNF43,RP9,RPN2,RTN3,RTN4,RYR2,RYR3,SACM1L,SC5D,SCAP,SCD5,SCFD1,SDCBP,SEC11C,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SERP1,SFTPB,SGK1,SGMS1,SGPL1,SLC28A3,SLC35B1,SLC51A,SPPL2A,SRI,SSR1,SSR2,SSR3,STIM2,STX5,TECR,TGFA,TLR7,TLR9,TMBIM6,TMC8,TMCO1,TMED2,TMEM106C,TMEM189,TMEM214,TMEM67,TMPO,TMX3,TOMM20,TOR1AIP2,TRAM1,TRIQK,TTC9,TTC9C,TTYH1,UBAC2,UBE2J2,UBXN4,UFL1,UGT1A1,UGT1A6,UNC93B1,ZC3H12A,ZDHHC16 190.5 0.02433 0.171768181818182 GO:0030894 replisome cellular_component 27 10 BCAS2,CHRAC1,HELB,PLRG1,POLA1,POLA2,POLD3,POLD4,PURA,RPA3 5.23 0.02456 0.171768181818182 GO:0019898 extrinsic component of membrane cellular_component 253 62 AAK1,ALOX15,ANXA2,ASPSCR1,BLK,BTK,CARMIL2,CDH1,CTNNA1,CYLD,DMBT1,DTNA,EEA1,EHD2,EPB41L3,EPN3,FARP1,FARP2,FES,FRMD3,GFRA2,GNA12,GNA14,GNG4,GNG7,GNGT1,KCNAB2,KRAS,MFGE8,MITD1,MTOR,NECTIN1,NMT1,NSMAF,NUCB1,OPA1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PTK2,PTK2B,RACGAP1,RGS6,SCUBE1,SNX16,SNX2,SNX4,SNX9,SYTL2,TF,TNK2,TYK2,USP8,VPS13A,VPS13C,WDR45B,ZAP70,ZC3H12A 48.98 0.02475 0.171768181818182 GO:0005658 alpha DNA polymerase:primase complex cellular_component 4 3 HELB,POLA1,POLA2 0.77 0.02480 0.171768181818182 GO:0005826 actomyosin contractile ring cellular_component 4 3 ANLN,MAEA,MYH9 0.77 0.02480 0.171768181818182 GO:0030289 protein phosphatase 4 complex cellular_component 4 3 PPP4C,PPP4R1,PPP4R3B 0.77 0.02480 0.171768181818182 GO:0035363 histone locus body cellular_component 4 3 ICE1,ICE2,ZC3H8 0.77 0.02480 0.171768181818182 GO:0000346 transcription export complex cellular_component 13 6 CHTOP,DDX39B,POLDIP3,THOC1,THOC2,THOC7 2.52 0.02579 0.175198829787234 GO:0032039 integrator complex cellular_component 13 6 CPSF3L,INTS10,INTS12,INTS6,INTS8,SHFM1 2.52 0.02579 0.175198829787234 GO:1990204 oxidoreductase complex cellular_component 101 28 BCKDHB,BCKDK,CYBB,DBT,DLAT,DLD,GCSH,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NOX1,NOX4,P4HA1,PDHB,PMPCB,RRM2B,SDHC,SDHD,UQCRB,UQCRC2 19.55 0.02597 0.175198829787234 GO:0005684 U2-type spliceosomal complex cellular_component 31 11 CWC22,DHX15,LUC7L,LUC7L3,PRPF18,PRPF39,PRPF40A,SF3B1,SF3B2,SF3B6,TFIP11 6 0.02611 0.175198829787234 GO:0070062 extracellular exosome cellular_component 2710 562 ABAT,ABCB1,ABCB4,ABI1,ACACA,ACAT1,ACE,ACP1,ACTG1,ACTN1,ACTR2,ACTR3C,ADAM10,ADGRG2,AEBP1,AHCTF1,AHNAK,AK2,AKR1A1,AKR1B1,AKR1E2,ALDH1A3,ALDH1L1,ALDH3A2,ALDH7A1,ALPL,ANO6,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,APPL1,APPL2,APRT,ARF1,ARHGEF12,ARL1,ARL6,ARL8A,ARMC3,ARPC1A,ARPC1B,ARSA,ART3,ASAH1,ASH1L,ATIC,ATP1B1,ATP2B1,ATP5B,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,BAX,BOLA2,BPIFB1,BPNT1,BPTF,BROX,C16orf89,C17orf80,C1QTNF5,C1RL,C1S,C2,C4A,C4B,C6orf120,C9orf142,CA1,CACNA2D1,CALB1,CALM1,CAND1,CAPS,CAPZA1,CCT3,CCT7,CD14,CD22,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC42,CDH1,CDH13,CEACAM5,CFAP20,CFHR3,CHCHD3,CHD2,CHID1,CHL1,CHMP3,CHMP5,CHMP6,CKAP4,CLASP1,CLDN11,CLRN3,CLTC,CLU,CMPK1,CNDP2,CNTN1,COASY,COL6A1,COPA,COX5A,CPNE1,CPNE3,CPQ,CR1,CREB5,CRTAC1,CRYAB,CRYM,CS,CSE1L,CTNND1,CUL3,CUL4B,CXCL12,CYFIP1,DAB2IP,DAD1,DAG1,DARS,DBI,DCTD,DCTN2,DCXR,DDB1,DDR1,DDR2,DDT,DDX23,DES,DHRS2,DMBT1,DMKN,DNAJA1,DNAJC13,DNASE1,DNM3,DPP3,DPYS,DSG2,DYSF,ECHDC1,EEA1,EFR3A,EGF,EHD2,EIF2S3,EIF3B,EIF4A1,EIF4E,EIF6,EML5,ENOPH1,ENTPD6,EPHA10,EPN3,EPS8L1,ERV3-1,ESD,ETFA,FABP5,FAM234A,FAM49B,FAS,FAT1,FBL,FBLN2,FBLN5,FBN1,FCER2,FIGNL1,FKBP4,FNBP1L,FTCD,FUT8,GALC,GALNT16,GALNT2,GARS,GART,GCNT3,GDA,GDI2,GEN1,GGCT,GGH,GGT1,GLA,GNA14,GNG4,GNG7,GNPTG,GOLGA4,GOLGA7,GP2,GPC1,GPC3,GPM6A,GPRC5B,GPX3,GRID1,GRM5,GSN,GSTA5,GSTCD,GSTP1,H2AFV,H2AFY,HAVCR2,HDHD2,HEXB,HGS,HIST1H2BN,HIST2H2AC,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPL,HNRNPM,HPRT1,HS6ST2,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HYAL1,IAH1,IGF2R,IGFBP2,IGSF11,IL18BP,IL1B,INPP5A,IQCB1,IQCG,ITFG1,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,ITM2C,ITSN2,JMJD8,KALRN,KCNMA1,KDELR2,KIFC3,KLK11,KLK12,KRT13,KRT16,KRT5,KRT7,KRT79,LAMP2,LAMTOR1,LAMTOR3,LCN2,LCP1,LOXL4,LSM6,LSP1,LTA4H,LTBP3,LTF,LYNX1,LYPD2,LYPLA1,MAL2,MAN1C1,MAN2A1,MARK3,MBD5,MCF2,MDH1,MEST,MFGE8,MGAT4A,MGRN1,MINK1,MITD1,MLPH,MME,MMRN2,MOB1A,MON2,MSRA,MT-ATP6,MT-CO2,MTHFD1,MUC4,MVP,MYH10,MYH9,MYL12A,MYLK,MYO1B,MYO1G,MYOC,NAA16,NAGK,NAPB,NAPEPLD,NAPG,NARS,NDRG2,NDUFB10,NDUFB3,NDUFB4,NDUFB9,NEB,NEDD4L,NIPBL,NIT2,NRAS,NTPCR,NUCB1,NUCB2,NUDT9,OCRL,OSBPL1A,OSCAR,PABPC1,PAFAH1B1,PCBD1,PCBP2,PCBP3,PCK2,PCMT1,PCOLCE2,PCYOX1,PDCD10,PDCD2,PDCD5,PDE8A,PDGFRB,PDHB,PDLIM2,PDXK,PDZK1,PDZK1IP1,PECAM1,PFDN2,PFN2,PGLYRP2,PHIP,PIGR,PITPNB,PKM,PLCB1,PLOD3,PLP2,PLSCR4,PLXDC2,PLXNA1,POGLUT1,PON1,PPFIA2,PPP1CB,PPP1R7,PPP2R1A,PPT2,PRDX4,PRKAR2A,PRKCZ,PROM1,PROSC,PRRC2A,PSAT1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PTGR2,PTH1R,PTP4A2,PTPN13,PTPN6,PTPRA,PTTG1IP,PXDN,QDPR,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB5A,RAC2,RACGAP1,RALB,RAP1A,RAP1B,RAP1GDS1,RARS,RASAL3,RBMX,RELT,RGMA,RHOC,RHOF,RNASET2,RNH1,RP2,RPL14,RPL22,RPL23,RPL26,RPL31,RPL35A,RPL4,RPL5,RPLP0,RPS19,RPS2,RPS5,RRAS2,RRM2B,RTN3,RTN4,RTN4RL2,RYR2,SAA2,SCN11A,SCNN1B,SDCBP,SELENBP1,SEPP1,SEPT2,SEPT7,SERBP1,SERPINA3,SERPINB4,SGSH,SHMT2,SLC22A11,SLC22A2,SLC26A11,SLC2A5,SLC36A2,SLC44A4,SLC5A1,SLC5A5,SLC6A13,SLC6A19,SMC2,SNAP23,SNED1,SNRPE,SNX2,SNX9,SOD3,SORL1,SPAG9,SPPL2A,SPTBN1,SPTBN4,SRI,SRSF7,SSBP1,ST3GAL6,ST6GAL1,STAMBP,STEAP4,STK10,STK25,STXBP2,STXBP4 524.65 0.02638 0.175198829787234 GO:1903561 extracellular vesicle cellular_component 2710 562 ABAT,ABCB1,ABCB4,ABI1,ACACA,ACAT1,ACE,ACP1,ACTG1,ACTN1,ACTR2,ACTR3C,ADAM10,ADGRG2,AEBP1,AHCTF1,AHNAK,AK2,AKR1A1,AKR1B1,AKR1E2,ALDH1A3,ALDH1L1,ALDH3A2,ALDH7A1,ALPL,ANO6,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,APPL1,APPL2,APRT,ARF1,ARHGEF12,ARL1,ARL6,ARL8A,ARMC3,ARPC1A,ARPC1B,ARSA,ART3,ASAH1,ASH1L,ATIC,ATP1B1,ATP2B1,ATP5B,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,BAX,BOLA2,BPIFB1,BPNT1,BPTF,BROX,C16orf89,C17orf80,C1QTNF5,C1RL,C1S,C2,C4A,C4B,C6orf120,C9orf142,CA1,CACNA2D1,CALB1,CALM1,CAND1,CAPS,CAPZA1,CCT3,CCT7,CD14,CD22,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC42,CDH1,CDH13,CEACAM5,CFAP20,CFHR3,CHCHD3,CHD2,CHID1,CHL1,CHMP3,CHMP5,CHMP6,CKAP4,CLASP1,CLDN11,CLRN3,CLTC,CLU,CMPK1,CNDP2,CNTN1,COASY,COL6A1,COPA,COX5A,CPNE1,CPNE3,CPQ,CR1,CREB5,CRTAC1,CRYAB,CRYM,CS,CSE1L,CTNND1,CUL3,CUL4B,CXCL12,CYFIP1,DAB2IP,DAD1,DAG1,DARS,DBI,DCTD,DCTN2,DCXR,DDB1,DDR1,DDR2,DDT,DDX23,DES,DHRS2,DMBT1,DMKN,DNAJA1,DNAJC13,DNASE1,DNM3,DPP3,DPYS,DSG2,DYSF,ECHDC1,EEA1,EFR3A,EGF,EHD2,EIF2S3,EIF3B,EIF4A1,EIF4E,EIF6,EML5,ENOPH1,ENTPD6,EPHA10,EPN3,EPS8L1,ERV3-1,ESD,ETFA,FABP5,FAM234A,FAM49B,FAS,FAT1,FBL,FBLN2,FBLN5,FBN1,FCER2,FIGNL1,FKBP4,FNBP1L,FTCD,FUT8,GALC,GALNT16,GALNT2,GARS,GART,GCNT3,GDA,GDI2,GEN1,GGCT,GGH,GGT1,GLA,GNA14,GNG4,GNG7,GNPTG,GOLGA4,GOLGA7,GP2,GPC1,GPC3,GPM6A,GPRC5B,GPX3,GRID1,GRM5,GSN,GSTA5,GSTCD,GSTP1,H2AFV,H2AFY,HAVCR2,HDHD2,HEXB,HGS,HIST1H2BN,HIST2H2AC,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPL,HNRNPM,HPRT1,HS6ST2,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HYAL1,IAH1,IGF2R,IGFBP2,IGSF11,IL18BP,IL1B,INPP5A,IQCB1,IQCG,ITFG1,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,ITM2C,ITSN2,JMJD8,KALRN,KCNMA1,KDELR2,KIFC3,KLK11,KLK12,KRT13,KRT16,KRT5,KRT7,KRT79,LAMP2,LAMTOR1,LAMTOR3,LCN2,LCP1,LOXL4,LSM6,LSP1,LTA4H,LTBP3,LTF,LYNX1,LYPD2,LYPLA1,MAL2,MAN1C1,MAN2A1,MARK3,MBD5,MCF2,MDH1,MEST,MFGE8,MGAT4A,MGRN1,MINK1,MITD1,MLPH,MME,MMRN2,MOB1A,MON2,MSRA,MT-ATP6,MT-CO2,MTHFD1,MUC4,MVP,MYH10,MYH9,MYL12A,MYLK,MYO1B,MYO1G,MYOC,NAA16,NAGK,NAPB,NAPEPLD,NAPG,NARS,NDRG2,NDUFB10,NDUFB3,NDUFB4,NDUFB9,NEB,NEDD4L,NIPBL,NIT2,NRAS,NTPCR,NUCB1,NUCB2,NUDT9,OCRL,OSBPL1A,OSCAR,PABPC1,PAFAH1B1,PCBD1,PCBP2,PCBP3,PCK2,PCMT1,PCOLCE2,PCYOX1,PDCD10,PDCD2,PDCD5,PDE8A,PDGFRB,PDHB,PDLIM2,PDXK,PDZK1,PDZK1IP1,PECAM1,PFDN2,PFN2,PGLYRP2,PHIP,PIGR,PITPNB,PKM,PLCB1,PLOD3,PLP2,PLSCR4,PLXDC2,PLXNA1,POGLUT1,PON1,PPFIA2,PPP1CB,PPP1R7,PPP2R1A,PPT2,PRDX4,PRKAR2A,PRKCZ,PROM1,PROSC,PRRC2A,PSAT1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PTGR2,PTH1R,PTP4A2,PTPN13,PTPN6,PTPRA,PTTG1IP,PXDN,QDPR,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB5A,RAC2,RACGAP1,RALB,RAP1A,RAP1B,RAP1GDS1,RARS,RASAL3,RBMX,RELT,RGMA,RHOC,RHOF,RNASET2,RNH1,RP2,RPL14,RPL22,RPL23,RPL26,RPL31,RPL35A,RPL4,RPL5,RPLP0,RPS19,RPS2,RPS5,RRAS2,RRM2B,RTN3,RTN4,RTN4RL2,RYR2,SAA2,SCN11A,SCNN1B,SDCBP,SELENBP1,SEPP1,SEPT2,SEPT7,SERBP1,SERPINA3,SERPINB4,SGSH,SHMT2,SLC22A11,SLC22A2,SLC26A11,SLC2A5,SLC36A2,SLC44A4,SLC5A1,SLC5A5,SLC6A13,SLC6A19,SMC2,SNAP23,SNED1,SNRPE,SNX2,SNX9,SOD3,SORL1,SPAG9,SPPL2A,SPTBN1,SPTBN4,SRI,SRSF7,SSBP1,ST3GAL6,ST6GAL1,STAMBP,STEAP4,STK10,STK25,STXBP2,STXBP4 524.65 0.02638 0.175198829787234 GO:0098798 mitochondrial protein complex cellular_component 145 38 ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,BAX,BCKDHB,BCKDK,COX5A,COX6A1,DBT,DLAT,DNA2,IMMP2L,MT-ATP6,MT-CO1,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,PNPT1,SDHC,SDHD,SPG7,TIMM10B,TIMM23B,TIMM50,TOMM20,UQCRB,UQCRC2 28.07 0.02639 0.175198829787234 GO:0031970 organelle envelope lumen cellular_component 84 24 AK2,ARL2BP,BCHE,CEP89,CHCHD7,COX17,COX6B2,CPOX,DIABLO,DTYMK,FBXL4,IGF2R,MYOC,NME4,OPA1,PNPT1,PRELID3A,REXO2,SHMT2,SIRT5,SORL1,STAR,THOP1,TIMM10B 16.26 0.02647 0.175198829787234 GO:0005839 proteasome core complex cellular_component 20 8 PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9 3.87 0.02675 0.175198829787234 GO:0005942 phosphatidylinositol 3-kinase complex cellular_component 20 8 MTOR,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5 3.87 0.02675 0.175198829787234 GO:0043230 extracellular organelle cellular_component 2711 562 ABAT,ABCB1,ABCB4,ABI1,ACACA,ACAT1,ACE,ACP1,ACTG1,ACTN1,ACTR2,ACTR3C,ADAM10,ADGRG2,AEBP1,AHCTF1,AHNAK,AK2,AKR1A1,AKR1B1,AKR1E2,ALDH1A3,ALDH1L1,ALDH3A2,ALDH7A1,ALPL,ANO6,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,APPL1,APPL2,APRT,ARF1,ARHGEF12,ARL1,ARL6,ARL8A,ARMC3,ARPC1A,ARPC1B,ARSA,ART3,ASAH1,ASH1L,ATIC,ATP1B1,ATP2B1,ATP5B,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,BAX,BOLA2,BPIFB1,BPNT1,BPTF,BROX,C16orf89,C17orf80,C1QTNF5,C1RL,C1S,C2,C4A,C4B,C6orf120,C9orf142,CA1,CACNA2D1,CALB1,CALM1,CAND1,CAPS,CAPZA1,CCT3,CCT7,CD14,CD22,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC42,CDH1,CDH13,CEACAM5,CFAP20,CFHR3,CHCHD3,CHD2,CHID1,CHL1,CHMP3,CHMP5,CHMP6,CKAP4,CLASP1,CLDN11,CLRN3,CLTC,CLU,CMPK1,CNDP2,CNTN1,COASY,COL6A1,COPA,COX5A,CPNE1,CPNE3,CPQ,CR1,CREB5,CRTAC1,CRYAB,CRYM,CS,CSE1L,CTNND1,CUL3,CUL4B,CXCL12,CYFIP1,DAB2IP,DAD1,DAG1,DARS,DBI,DCTD,DCTN2,DCXR,DDB1,DDR1,DDR2,DDT,DDX23,DES,DHRS2,DMBT1,DMKN,DNAJA1,DNAJC13,DNASE1,DNM3,DPP3,DPYS,DSG2,DYSF,ECHDC1,EEA1,EFR3A,EGF,EHD2,EIF2S3,EIF3B,EIF4A1,EIF4E,EIF6,EML5,ENOPH1,ENTPD6,EPHA10,EPN3,EPS8L1,ERV3-1,ESD,ETFA,FABP5,FAM234A,FAM49B,FAS,FAT1,FBL,FBLN2,FBLN5,FBN1,FCER2,FIGNL1,FKBP4,FNBP1L,FTCD,FUT8,GALC,GALNT16,GALNT2,GARS,GART,GCNT3,GDA,GDI2,GEN1,GGCT,GGH,GGT1,GLA,GNA14,GNG4,GNG7,GNPTG,GOLGA4,GOLGA7,GP2,GPC1,GPC3,GPM6A,GPRC5B,GPX3,GRID1,GRM5,GSN,GSTA5,GSTCD,GSTP1,H2AFV,H2AFY,HAVCR2,HDHD2,HEXB,HGS,HIST1H2BN,HIST2H2AC,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPL,HNRNPM,HPRT1,HS6ST2,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HYAL1,IAH1,IGF2R,IGFBP2,IGSF11,IL18BP,IL1B,INPP5A,IQCB1,IQCG,ITFG1,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,ITM2C,ITSN2,JMJD8,KALRN,KCNMA1,KDELR2,KIFC3,KLK11,KLK12,KRT13,KRT16,KRT5,KRT7,KRT79,LAMP2,LAMTOR1,LAMTOR3,LCN2,LCP1,LOXL4,LSM6,LSP1,LTA4H,LTBP3,LTF,LYNX1,LYPD2,LYPLA1,MAL2,MAN1C1,MAN2A1,MARK3,MBD5,MCF2,MDH1,MEST,MFGE8,MGAT4A,MGRN1,MINK1,MITD1,MLPH,MME,MMRN2,MOB1A,MON2,MSRA,MT-ATP6,MT-CO2,MTHFD1,MUC4,MVP,MYH10,MYH9,MYL12A,MYLK,MYO1B,MYO1G,MYOC,NAA16,NAGK,NAPB,NAPEPLD,NAPG,NARS,NDRG2,NDUFB10,NDUFB3,NDUFB4,NDUFB9,NEB,NEDD4L,NIPBL,NIT2,NRAS,NTPCR,NUCB1,NUCB2,NUDT9,OCRL,OSBPL1A,OSCAR,PABPC1,PAFAH1B1,PCBD1,PCBP2,PCBP3,PCK2,PCMT1,PCOLCE2,PCYOX1,PDCD10,PDCD2,PDCD5,PDE8A,PDGFRB,PDHB,PDLIM2,PDXK,PDZK1,PDZK1IP1,PECAM1,PFDN2,PFN2,PGLYRP2,PHIP,PIGR,PITPNB,PKM,PLCB1,PLOD3,PLP2,PLSCR4,PLXDC2,PLXNA1,POGLUT1,PON1,PPFIA2,PPP1CB,PPP1R7,PPP2R1A,PPT2,PRDX4,PRKAR2A,PRKCZ,PROM1,PROSC,PRRC2A,PSAT1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PTGR2,PTH1R,PTP4A2,PTPN13,PTPN6,PTPRA,PTTG1IP,PXDN,QDPR,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB5A,RAC2,RACGAP1,RALB,RAP1A,RAP1B,RAP1GDS1,RARS,RASAL3,RBMX,RELT,RGMA,RHOC,RHOF,RNASET2,RNH1,RP2,RPL14,RPL22,RPL23,RPL26,RPL31,RPL35A,RPL4,RPL5,RPLP0,RPS19,RPS2,RPS5,RRAS2,RRM2B,RTN3,RTN4,RTN4RL2,RYR2,SAA2,SCN11A,SCNN1B,SDCBP,SELENBP1,SEPP1,SEPT2,SEPT7,SERBP1,SERPINA3,SERPINB4,SGSH,SHMT2,SLC22A11,SLC22A2,SLC26A11,SLC2A5,SLC36A2,SLC44A4,SLC5A1,SLC5A5,SLC6A13,SLC6A19,SMC2,SNAP23,SNED1,SNRPE,SNX2,SNX9,SOD3,SORL1,SPAG9,SPPL2A,SPTBN1,SPTBN4,SRI,SRSF7,SSBP1,ST3GAL6,ST6GAL1,STAMBP,STEAP4,STK10,STK25,STXBP2,STXBP4 524.84 0.02702 0.175198829787234 GO:0065010 extracellular membrane-bounded organelle cellular_component 2711 562 ABAT,ABCB1,ABCB4,ABI1,ACACA,ACAT1,ACE,ACP1,ACTG1,ACTN1,ACTR2,ACTR3C,ADAM10,ADGRG2,AEBP1,AHCTF1,AHNAK,AK2,AKR1A1,AKR1B1,AKR1E2,ALDH1A3,ALDH1L1,ALDH3A2,ALDH7A1,ALPL,ANO6,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,APPL1,APPL2,APRT,ARF1,ARHGEF12,ARL1,ARL6,ARL8A,ARMC3,ARPC1A,ARPC1B,ARSA,ART3,ASAH1,ASH1L,ATIC,ATP1B1,ATP2B1,ATP5B,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,BAX,BOLA2,BPIFB1,BPNT1,BPTF,BROX,C16orf89,C17orf80,C1QTNF5,C1RL,C1S,C2,C4A,C4B,C6orf120,C9orf142,CA1,CACNA2D1,CALB1,CALM1,CAND1,CAPS,CAPZA1,CCT3,CCT7,CD14,CD22,CD44,CD46,CD7,CD74,CD79B,CD81,CD82,CD9,CDC42,CDH1,CDH13,CEACAM5,CFAP20,CFHR3,CHCHD3,CHD2,CHID1,CHL1,CHMP3,CHMP5,CHMP6,CKAP4,CLASP1,CLDN11,CLRN3,CLTC,CLU,CMPK1,CNDP2,CNTN1,COASY,COL6A1,COPA,COX5A,CPNE1,CPNE3,CPQ,CR1,CREB5,CRTAC1,CRYAB,CRYM,CS,CSE1L,CTNND1,CUL3,CUL4B,CXCL12,CYFIP1,DAB2IP,DAD1,DAG1,DARS,DBI,DCTD,DCTN2,DCXR,DDB1,DDR1,DDR2,DDT,DDX23,DES,DHRS2,DMBT1,DMKN,DNAJA1,DNAJC13,DNASE1,DNM3,DPP3,DPYS,DSG2,DYSF,ECHDC1,EEA1,EFR3A,EGF,EHD2,EIF2S3,EIF3B,EIF4A1,EIF4E,EIF6,EML5,ENOPH1,ENTPD6,EPHA10,EPN3,EPS8L1,ERV3-1,ESD,ETFA,FABP5,FAM234A,FAM49B,FAS,FAT1,FBL,FBLN2,FBLN5,FBN1,FCER2,FIGNL1,FKBP4,FNBP1L,FTCD,FUT8,GALC,GALNT16,GALNT2,GARS,GART,GCNT3,GDA,GDI2,GEN1,GGCT,GGH,GGT1,GLA,GNA14,GNG4,GNG7,GNPTG,GOLGA4,GOLGA7,GP2,GPC1,GPC3,GPM6A,GPRC5B,GPX3,GRID1,GRM5,GSN,GSTA5,GSTCD,GSTP1,H2AFV,H2AFY,HAVCR2,HDHD2,HEXB,HGS,HIST1H2BN,HIST2H2AC,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPK,HNRNPL,HNRNPM,HPRT1,HS6ST2,HSP90B1,HSPA8,HSPB11,HSPD1,HSPH1,HYAL1,IAH1,IGF2R,IGFBP2,IGSF11,IL18BP,IL1B,INPP5A,IQCB1,IQCG,ITFG1,ITGAL,ITGAV,ITGB1BP1,ITGB4,ITGB6,ITGB8,ITM2C,ITSN2,JMJD8,KALRN,KCNMA1,KDELR2,KIFC3,KLK11,KLK12,KRT13,KRT16,KRT5,KRT7,KRT79,LAMP2,LAMTOR1,LAMTOR3,LCN2,LCP1,LOXL4,LSM6,LSP1,LTA4H,LTBP3,LTF,LYNX1,LYPD2,LYPLA1,MAL2,MAN1C1,MAN2A1,MARK3,MBD5,MCF2,MDH1,MEST,MFGE8,MGAT4A,MGRN1,MINK1,MITD1,MLPH,MME,MMRN2,MOB1A,MON2,MSRA,MT-ATP6,MT-CO2,MTHFD1,MUC4,MVP,MYH10,MYH9,MYL12A,MYLK,MYO1B,MYO1G,MYOC,NAA16,NAGK,NAPB,NAPEPLD,NAPG,NARS,NDRG2,NDUFB10,NDUFB3,NDUFB4,NDUFB9,NEB,NEDD4L,NIPBL,NIT2,NRAS,NTPCR,NUCB1,NUCB2,NUDT9,OCRL,OSBPL1A,OSCAR,PABPC1,PAFAH1B1,PCBD1,PCBP2,PCBP3,PCK2,PCMT1,PCOLCE2,PCYOX1,PDCD10,PDCD2,PDCD5,PDE8A,PDGFRB,PDHB,PDLIM2,PDXK,PDZK1,PDZK1IP1,PECAM1,PFDN2,PFN2,PGLYRP2,PHIP,PIGR,PITPNB,PKM,PLCB1,PLOD3,PLP2,PLSCR4,PLXDC2,PLXNA1,POGLUT1,PON1,PPFIA2,PPP1CB,PPP1R7,PPP2R1A,PPT2,PRDX4,PRKAR2A,PRKCZ,PROM1,PROSC,PRRC2A,PSAT1,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PTGR2,PTH1R,PTP4A2,PTPN13,PTPN6,PTPRA,PTTG1IP,PXDN,QDPR,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB2B,RAB5A,RAC2,RACGAP1,RALB,RAP1A,RAP1B,RAP1GDS1,RARS,RASAL3,RBMX,RELT,RGMA,RHOC,RHOF,RNASET2,RNH1,RP2,RPL14,RPL22,RPL23,RPL26,RPL31,RPL35A,RPL4,RPL5,RPLP0,RPS19,RPS2,RPS5,RRAS2,RRM2B,RTN3,RTN4,RTN4RL2,RYR2,SAA2,SCN11A,SCNN1B,SDCBP,SELENBP1,SEPP1,SEPT2,SEPT7,SERBP1,SERPINA3,SERPINB4,SGSH,SHMT2,SLC22A11,SLC22A2,SLC26A11,SLC2A5,SLC36A2,SLC44A4,SLC5A1,SLC5A5,SLC6A13,SLC6A19,SMC2,SNAP23,SNED1,SNRPE,SNX2,SNX9,SOD3,SORL1,SPAG9,SPPL2A,SPTBN1,SPTBN4,SRI,SRSF7,SSBP1,ST3GAL6,ST6GAL1,STAMBP,STEAP4,STK10,STK25,STXBP2,STXBP4 524.84 0.02702 0.175198829787234 GO:0005765 lysosomal membrane cellular_component 282 68 ABCA2,ABCA5,AHNAK,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,CCZ1,CCZ1B,CD1B,CD74,CLN3,CLTA,CLTC,COL6A1,DNAJC13,DRAM2,EGF,EVA1A,GDAP2,GPR137B,HGSNAT,HLA-DMB,HLA-DPB1,HSPA8,IGF2R,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LITAF,LNPEP,M6PR,MTOR,NAPG,OSBPL1A,PLD1,PLEKHM1,RAB2A,RNF13,RRAGB,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAPIN,SNX14,SPNS3,SPPL2A,STX8,TLR7,TLR9,TMEM165,TMEM175,TMEM9,UBA52,VPS11,WDR11,WDR41,ZNRF2 54.59 0.02725 0.175686804123711 GO:0042175 nuclear outer membrane-endoplasmic retic... cellular_component 1002 218 ABCC6,ACSL1,ALDH3A2,ALG13,ALG9,ANKLE2,ANXA7,APH1A,APOO,ATL2,ATP11C,ATP2A3,ATXN3,BAX,BCL2,BET1,BOK,CALU,CAMK2G,CASP4,CD74,CDC42,CDKAL1,CDS2,CERS2,CKAP4,CLN3,CLN8,CNIH1,CNIH2,COPA,COPB1,CPT1C,CTDNEP1,CYBB,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,DAD1,DDOST,DEGS1,DHCR7,DMPK,DNAJB14,DNAJC1,DNM1L,DPAGT1,DUOXA1,EGFR,EI24,ELOVL6,ELOVL7,EMC10,EMC2,ERAP2,ERO1A,EVA1A,FADS1,FAF1,FAXDC2,FKBP3,FKBP4,FKBP6,FKBP8,FMN2,FTCD,GALNT2,GBA2,GGCX,GJB1,GPSM1,HACD1,HACD3,HHATL,HLA-DPB1,HSD17B3,HSD17B7,HSP90B1,ITPR1,JKAMP,KDELR2,KDSR,KTN1,LBR,LMF2,LPCAT3,LPCAT4,LPGAT1,LPIN1,LRAT,LRPPRC,LRRC8B,LSS,MARCH5,MARCH6,MCFD2,MEST,MFSD2A,MIA3,MOXD1,MR1,MSMO1,MTDH,MTOR,NFE2L1,NOX4,NOX5,NPLOC4,NR3C2,NSDHL,ORMDL2,ORMDL3,OSBPL3,OSBPL5,OSBPL8,OSTC,PCYT1A,PEX16,PGAP1,PGAP3,PIGA,PIGN,PIGQ,PIGT,PITPNB,PLA2G4C,PLD1,PLOD3,PLP2,POMT2,POR,PREB,PTDSS1,RAB18,RAB1A,RAB2A,RAB2B,RAB3GAP2,RDH10,RHBDD1,RNF121,RNF13,RNF43,RP9,RPN2,RTN3,RTN4,RYR2,RYR3,SACM1L,SC5D,SCAP,SCD5,SCFD1,SDCBP,SEC11C,SEC22C,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SEC61B,SEC63,SERP1,SFTPB,SGK1,SGMS1,SGPL1,SLC28A3,SLC35B1,SLC51A,SPPL2A,SRI,SSR1,SSR2,SSR3,STIM2,STX5,SYNE1,TECR,TGFA,TLR7,TLR9,TMBIM6,TMC8,TMCO1,TMED2,TMEM106C,TMEM189,TMEM214,TMEM67,TMPO,TMX3,TOMM20,TOR1AIP2,TRAM1,TRIQK,TTC9,TTC9C,TTYH1,UBAC2,UBE2J2,UBXN4,UFL1,UGT1A1,UGT1A6,UNC93B1,XPO1,ZC3H12A,ZDHHC16 193.98 0.02765 0.175686804123711 GO:0015030 Cajal body cellular_component 51 16 AK6,ANGEL2,ANKS1B,DDX42,FAM118B,FBL,ICE1,ICE2,NOP10,NOP58,RDM1,SART3,SRRM2,USPL1,XPO1,ZC3H8 9.87 0.02777 0.175686804123711 GO:0000785 chromatin cellular_component 423 98 ACTL6A,AHCTF1,ATRX,BAHCC1,BAZ2A,BCAS3,BUD31,CBX5,CENPA,CENPC,CSNK2A1,CTR9,DDX6,EHMT2,ESR1,EZH2,FAM111A,GATAD2B,H2AFV,H2AFY,HAT1,HDAC1,HDAC2,HELLS,HIST1H2BN,HIST2H2AC,HMGA2,HMGN1,HNRNPC,HNRNPK,ICE1,ICE2,INCENP,INO80,INO80C,INO80E,JMJD1C,JUND,KAT6A,L3MBTL1,MAGED1,MAU2,MBD3,MCM2,MCMBP,MEF2A,MORF4L1,MTBP,NASP,NCOA1,NCOR1,NCOR2,NFATC1,NFE2L2,NIPBL,NPM2,NUCKS1,PARPBP,PAWR,PDS5B,PHF12,PLCB1,POLA1,PSIP1,RAD51AP1,RBBP4,RBMX,RNF2,RRP8,RXRA,SFPQ,SIRT2,SIRT6,SLF1,SMAD2,SMAD4,SMARCA2,SMARCAD1,SMARCD2,SMARCE1,SP1,STAT6,SUMO1,TCF12,TCF7,TCP1,TMPO,TNRC18,TOP2B,TP63,TTC21B,TTC37,UBE2B,UCHL5,USP3,WAPL,ZC3H8,ZNF385A 81.89 0.02784 0.175686804123711 GO:0034399 nuclear periphery cellular_component 119 32 AHCTF1,ATF4,ATXN3,ATXN7,CASK,DDX39B,HAT1,HNRNPM,MAEA,MYB,NARF,NCOR2,NUP107,NUP205,NUP35,NUP98,POLA1,PRKCZ,PRPF40A,PSMA6,RANBP6,RUNX1T1,SFPQ,SMARCAD1,SPTBN4,TELO2,TGFB1I1,THOC1,TNPO1,XPOT,YEATS4,ZNF326 23.04 0.02784 0.175686804123711 GO:0030120 vesicle coat cellular_component 47 15 AP1G2,CLTA,CLTC,COPA,COPB1,EGFR,LDLRAP1,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SGIP1,TBC1D5 9.1 0.02796 0.175686804123711 GO:0031010 ISWI-type complex cellular_component 10 5 BAZ1A,BPTF,CHRAC1,RBBP4,SMARCA5 1.94 0.02871 0.177652233502538 GO:0031080 nuclear pore outer ring cellular_component 10 5 AHCTF1,NUP107,NUP37,NUP98,SEH1L 1.94 0.02871 0.177652233502538 GO:0070938 contractile ring cellular_component 10 5 ANLN,DAG1,MAEA,MYH9,PRC1 1.94 0.02871 0.177652233502538 GO:0030915 Smc5-Smc6 complex cellular_component 7 4 NSMCE1,NSMCE2,NSMCE4A,SMC6 1.36 0.02978 0.1815091 GO:0070578 RISC-loading complex cellular_component 7 4 AGO1,AGO2,DICER1,TARBP2 1.36 0.02978 0.1815091 GO:0071541 eukaryotic translation initiation factor... cellular_component 7 4 EIF3B,EIF3D,EIF3F,EIF3M 1.36 0.02978 0.1815091 GO:0000323 lytic vacuole cellular_component 535 121 ABCA2,ABCA5,ACE,ADA,AHNAK,AKR1B1,ANK3,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ARSA,ASAH1,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,BBC3,BTK,CCZ1,CCZ1B,CD1B,CD74,CHID1,CHIT1,CLN3,CLTA,CLTC,COL6A1,CPLX2,CPQ,CRHBP,CXCR2,DNAJC13,DRAM2,EGF,ENGASE,EVA1A,FNBP1,GALC,GDAP2,GGH,GIF,GLA,GPC1,GPC3,GPR137B,HAP1,HEXB,HGSNAT,HLA-DMB,HLA-DPB1,HSPA8,HYAL1,HYAL3,IGF2R,IL1B,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LAT,LITAF,LNPEP,LRBA,M6PR,MTOR,NAPG,NEU4,OSBPL1A,PAX2,PCYOX1,PDGFRB,PIK3C3,PIK3CD,PLBD1,PLD1,PLEKHM1,PON2,PPT2,RAB2A,RNASET2,RNF13,RRAGB,SFTPB,SGSH,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAP23,SNAPIN,SNX14,SNX16,SPNS3,SPPL2A,STX8,STXBP2,TIAL1,TLR7,TLR9,TMEM165,TMEM175,TMEM9,TOM1L1,TRIP10,UBA52,UNC93B1,USP4,UVRAG,VAMP4,VPS11,VPS36,VPS4A,WDR11,WDR41,ZNRF2 103.57 0.03174 0.19071645320197 GO:0005764 lysosome cellular_component 535 121 ABCA2,ABCA5,ACE,ADA,AHNAK,AKR1B1,ANK3,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ARSA,ASAH1,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,BBC3,BTK,CCZ1,CCZ1B,CD1B,CD74,CHID1,CHIT1,CLN3,CLTA,CLTC,COL6A1,CPLX2,CPQ,CRHBP,CXCR2,DNAJC13,DRAM2,EGF,ENGASE,EVA1A,FNBP1,GALC,GDAP2,GGH,GIF,GLA,GPC1,GPC3,GPR137B,HAP1,HEXB,HGSNAT,HLA-DMB,HLA-DPB1,HSPA8,HYAL1,HYAL3,IGF2R,IL1B,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LAT,LITAF,LNPEP,LRBA,M6PR,MTOR,NAPG,NEU4,OSBPL1A,PAX2,PCYOX1,PDGFRB,PIK3C3,PIK3CD,PLBD1,PLD1,PLEKHM1,PON2,PPT2,RAB2A,RNASET2,RNF13,RRAGB,SFTPB,SGSH,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAP23,SNAPIN,SNX14,SNX16,SPNS3,SPPL2A,STX8,STXBP2,TIAL1,TLR7,TLR9,TMEM165,TMEM175,TMEM9,TOM1L1,TRIP10,UBA52,UNC93B1,USP4,UVRAG,VAMP4,VPS11,VPS36,VPS4A,WDR11,WDR41,ZNRF2 103.57 0.03174 0.19071645320197 GO:0042734 presynaptic membrane cellular_component 60 18 ADORA1,APBB1,CADPS2,CAMK2A,CASK,ERC1,ERC2,GABBR1,GRM7,GRM8,NECTIN1,NRXN1,PDE2A,PICK1,RIMS1,SYT1,ZDHHC17,ZNRF2 11.62 0.03176 0.19071645320197 GO:0005913 cell-cell adherens junction cellular_component 317 75 ABI1,ACTN1,AHNAK,ANLN,ANXA2,ARGLU1,ARHGEF16,ATIC,CAMSAP3,CAPZA1,CCNB2,CD200,CDH1,CHMP5,CTNNA1,CTNNA3,CTNND1,DAB2IP,DAG1,DDX6,DES,EEF1D,EGFR,EIF2A,EIF2S3,EIF4G2,EIF4H,EPS8L1,ERC1,FMNL2,FNBP1L,GIGYF2,HDLBP,HNRNPK,HSPA8,ITGA6,KIAA1524,KIFC3,KTN1,MYH9,MYO1B,NCK1,NECTIN1,NOP56,PAK2,PCMT1,PKM,PKP2,PPFIBP1,RAB1A,RARS,RPL14,RPL6,RPS2,RTN4,SDCBP,SEPT2,SEPT7,SEPT9,SERBP1,SH3GL1,SHTN1,SNX2,SNX9,SPTBN1,SSX2IP,STX5,TLN1,TMPO,TRIM29,TWF1,USP8,YKT6,YWHAZ,ZYX 61.37 0.03208 0.191693725490196 GO:0005881 cytoplasmic microtubule cellular_component 56 17 ARL6,BCAS3,BICD1,CLASP1,CLASP2,CLIP1,CLIP2,CYLD,CYP2A6,DCXR,HDAC6,MAP9,ODF3L2,PAFAH1B1,SERP1,SS18,TMEM214 10.84 0.03249 0.193196634146341 GO:0008023 transcription elongation factor complex cellular_component 52 16 CCNT1,CCNT2,CTR9,EAF2,ELL2,ELP2,ELP4,ICE1,ICE2,LEO1,MMS22L,SUPT4H1,TCEA2,TCEB1,THOC7,ZC3H8 10.07 0.03312 0.194629759615385 GO:0030117 membrane coat cellular_component 90 25 AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,ARL6,CLTA,CLTC,COPA,COPB1,EGFR,GGA1,IGF2R,LDLRAP1,PANK1,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SGIP1,TBC1D5 17.42 0.03321 0.194629759615385 GO:0048475 coated membrane cellular_component 90 25 AP1G1,AP1G2,AP1M2,AP1S2,AP3M2,AP3S1,AP5Z1,ARL6,CLTA,CLTC,COPA,COPB1,EGFR,GGA1,IGF2R,LDLRAP1,PANK1,SEC23B,SEC24A,SEC24B,SEC24D,SEC31A,SEC31B,SGIP1,TBC1D5 17.42 0.03321 0.194629759615385 GO:0031519 PcG protein complex cellular_component 44 14 BAP1,CSNK2A1,CSNK2A2,EZH2,H2AFY,HDAC2,MTF2,PCGF3,PHC3,PHF1,RBBP4,RBBP7,RNF2,UBAP2L 8.52 0.03391 0.197187761904762 GO:0032421 stereocilium bundle cellular_component 40 13 BBS2,CDH23,CIB2,DOCK4,ELMOD3,FAM65B,GRXCR2,IDO1,KNCN,STRC,TRPA1,USH1C,USH2A 7.74 0.03397 0.197187761904762 GO:0044445 cytosolic part cellular_component 253 61 AHR,CASP4,CASP8,CCT3,CCT7,CFLAR,CHUK,COA1,ENO4,ERC1,FADD,GET4,MCTS1,MRPL1,MRPS18C,MTOR,NAA10,PFDN1,PFDN2,PFKFB1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD2,RPL13,RPL14,RPL17,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL32,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL7L1,RPL8,RPLP0,RPS19,RPS2,RPS5,RSL24D1,SNAPIN,SNU13,TCP1,UCHL5,VBP1 48.98 0.03496 0.201972701421801 GO:0035327 transcriptionally active chromatin cellular_component 21 8 BCAS3,CTR9,ESR1,ICE1,ICE2,PSIP1,TTC37,ZC3H8 4.07 0.03606 0.203910401785714 GO:0009898 cytoplasmic side of plasma membrane cellular_component 153 39 ACP1,ALOX15,ASPSCR1,ATP2B1,BLK,BTK,CACNB4,CARMIL2,CDH1,CHUK,CYLD,DAB2IP,DIABLO,DTNA,FARP1,FES,GNA12,GNA14,GNG4,GNG7,GNGT1,KCNAB2,KRAS,LDLRAP1,NF1,PKP4,PTEN,PTK2,PTK2B,RACGAP1,RASA2,RASA3,RASAL3,RGS6,SNX9,SPTB,TNK2,TYK2,ZAP70 29.62 0.03724 0.203910401785714 GO:0001651 dense fibrillar component cellular_component 2 2 FBL,SNU13 0.39 0.03747 0.203910401785714 GO:0005668 RNA polymerase transcription factor SL1 ... cellular_component 2 2 TAF1B,TAF1D 0.39 0.03747 0.203910401785714 GO:0008623 CHRAC cellular_component 2 2 BAZ1A,CHRAC1 0.39 0.03747 0.203910401785714 GO:0017109 glutamate-cysteine ligase complex cellular_component 2 2 GCLC,GCLM 0.39 0.03747 0.203910401785714 GO:0031416 NatB complex cellular_component 2 2 NAA20,NAA25 0.39 0.03747 0.203910401785714 GO:0031510 SUMO activating enzyme complex cellular_component 2 2 SAE1,UBA2 0.39 0.03747 0.203910401785714 GO:0032116 SMC loading complex cellular_component 2 2 MAU2,NIPBL 0.39 0.03747 0.203910401785714 GO:0033065 Rad51C-XRCC3 complex cellular_component 2 2 RAD51C,XRCC3 0.39 0.03747 0.203910401785714 GO:0034515 proteasome storage granule cellular_component 2 2 PSMD1,PSMD2 0.39 0.03747 0.203910401785714 GO:0034686 integrin alphav-beta8 complex cellular_component 2 2 ITGAV,ITGB8 0.39 0.03747 0.203910401785714 GO:0035692 macrophage migration inhibitory factor r... cellular_component 2 2 CD44,CD74 0.39 0.03747 0.203910401785714 GO:0016234 inclusion body cellular_component 70 20 ARIH1,ATF4,ATXN3,CABIN1,CCZ1,CCZ1B,CDH1,CLU,FBXO7,GYS1,HAP1,HDAC6,NUP98,PABPN1,PSMC4,PSMC5,RAD18,RANBP2,RNF32,SLF1 13.55 0.04027 0.218173911111111 GO:0005746 mitochondrial respiratory chain cellular_component 83 23 COX5A,COX6A1,COX7A2L,MT-CO1,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,NNT,PMPCB,SDHC,SDHD,SURF1,UQCRB,UQCRC2,UQCRH 16.07 0.04091 0.220225506607929 GO:0005773 vacuole cellular_component 632 140 ABCA2,ABCA5,ACE,ADA,AHNAK,AKR1B1,AKTIP,AMBRA1,ANK3,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ARSA,ASAH1,ATG16L2,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,BBC3,BTK,CALCOCO2,CCZ1,CCZ1B,CD1B,CD74,CDC42,CHID1,CHIT1,CLN3,CLTA,CLTC,COL6A1,CPA2,CPLX2,CPQ,CRHBP,CXCR2,DLD,DNAJC13,DRAM2,EGF,ENGASE,EVA1A,FNBP1,GALC,GDAP2,GGH,GIF,GLA,GLB1L3,GPC1,GPC3,GPR137B,HAP1,HEXB,HGSNAT,HLA-DMB,HLA-DPB1,HOOK1,HSPA8,HYAL1,HYAL3,IGF2R,IL1B,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LAT,LITAF,LNPEP,LRBA,LTV1,M6PR,MAN2C1,MAP1LC3B,MST1R,MTOR,NAPB,NAPG,NEU4,NPRL3,OSBPL1A,PAX2,PCYOX1,PDGFRB,PIK3C3,PIK3CD,PLBD1,PLD1,PLEKHM1,PON2,PPT2,RAB2A,RALB,RNASET2,RNF13,RPN2,RRAGB,SFTPB,SGSH,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAP23,SNAPIN,SNX14,SNX16,SPNS3,SPPL2A,STX8,STXBP2,TBC1D5,TIAL1,TLR7,TLR9,TMEM165,TMEM175,TMEM9,TOM1L1,TRIP10,UBA52,UNC93B1,USP33,USP4,UVRAG,VAMP4,VPS11,VPS36,VPS4A,WDR11,WDR41,ZNRF2 122.35 0.04101 0.220225506607929 GO:0044437 vacuolar part cellular_component 411 94 ABCA2,ABCA5,AHNAK,AKTIP,ANXA2,ANXA6,AP1G1,AP1M2,AP1S2,ARL8A,ARSA,ASAH1,ATG16L2,ATP11C,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATRAID,CALCOCO2,CCZ1,CCZ1B,CD1B,CD74,CLN3,CLTA,CLTC,COL6A1,DLD,DNAJC13,DRAM2,EGF,EVA1A,GALC,GDAP2,GIF,GLA,GPC1,GPC3,GPR137B,HEXB,HGSNAT,HLA-DMB,HLA-DPB1,HOOK1,HSPA8,HYAL1,IGF2R,ITM2C,LAMP2,LAMTOR1,LAMTOR3,LITAF,LNPEP,LTV1,M6PR,MAP1LC3B,MTOR,NAPB,NAPG,NEU4,OSBPL1A,PCYOX1,PDGFRB,PLD1,PLEKHM1,PPT2,RAB2A,RNASET2,RNF13,RPN2,RRAGB,SGSH,SIDT2,SLC11A2,SLC26A11,SLC30A3,SLC38A9,SNAPIN,SNX14,SPNS3,SPPL2A,STX8,TLR7,TLR9,TMEM165,TMEM175,TMEM9,UBA52,UVRAG,VPS11,VPS4A,WDR11,WDR41,ZNRF2 79.57 0.04126 0.220596228070175 GO:0030880 RNA polymerase complex cellular_component 123 32 CDK7,CHD6,CPSF3L,CRCP,CTR9,GTF2H2,GTF2H3,HELB,INTS10,INTS12,INTS6,INTS8,LEO1,MED14,MED31,MNAT1,PAPD4,POLA1,POLA2,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2K,POLR3C,POLR3F,RECQL5,RPRD2,SHFM1,TAF2,TBPL1 23.81 0.04276 0.227617641921397 GO:0005666 DNA-directed RNA polymerase III complex cellular_component 18 7 CRCP,POLR1D,POLR2E,POLR2H,POLR2K,POLR3C,POLR3F 3.48 0.04375 0.231875 GO:0030684 preribosome cellular_component 75 21 BMS1,DCAF13,EIF6,FBL,HEATR1,KRR1,LTV1,MPHOSPH10,NGDN,NOP56,NOP58,NSA2,RPF1,RPLP0,RRP1,RRP36,SNU13,UTP11,UTP14A,UTP4,WDR12 14.52 0.04439 0.233291379310345 GO:0002116 semaphorin receptor complex cellular_component 11 5 NRP2,PLXNA1,PLXNB1,PLXNC1,PLXND1 2.13 0.04440 0.233291379310345 GO:0019897 extrinsic component of plasma membrane cellular_component 137 35 AAK1,ALOX15,ANXA2,BLK,BTK,CARMIL2,CDH1,CTNNA1,CYLD,DTNA,EEA1,EPN3,FARP1,FES,GNA12,GNA14,GNG4,GNG7,GNGT1,KCNAB2,KRAS,MFGE8,NECTIN1,PTK2,PTK2B,RACGAP1,RGS6,SCUBE1,SNX9,SYTL2,TF,TNK2,TYK2,USP8,ZAP70 26.52 0.04509 0.235900042918455 GO:0098800 inner mitochondrial membrane protein com... cellular_component 111 29 ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,COX5A,COX6A1,IMMP2L,MT-ATP6,MT-CO1,MT-ND4,MT-ND4L,NDUFA3,NDUFA7,NDUFA9,NDUFB10,NDUFB3,NDUFB4,NDUFB5,NDUFB9,NDUFS8,PMPCB,SDHC,SDHD,SPG7,TIMM23B,TIMM50,UQCRB,UQCRC2 21.49 0.04931 0.245693143939394 GO:0034451 centriolar satellite cellular_component 26 9 CCDC14,CEP290,KIAA0753,OFD1,PAX2,PCM1,SDCCAG8,SPAG5,SSX2IP 5.03 0.04935 0.245693143939394 GO:0000152 nuclear ubiquitin ligase complex cellular_component 42 13 ANAPC10,ANAPC4,ANAPC5,ANAPC7,BRCA1,BUB1B,CACUL1,CDC23,CDC27,FZR1,PHC3,RNF2,RNF4 8.13 0.04944 0.245693143939394 GO:0000123 histone acetyltransferase complex cellular_component 89 24 ACTL6A,ATXN7,DR1,ELP2,ELP4,ENY2,JADE1,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,MEAF6,MORF4L1,OGT,PHF20,SUPT20H,TAF2,UBAP2L,USP34,WDR75,YEATS4,ZZZ3 17.23 0.04999 0.245693143939394 GO:0004842 ubiquitin-protein transferase activity molecular_function 422 114 ANAPC10,ANAPC4,ANAPC5,ANAPC7,ARIH1,ASB15,BIRC3,BIRC6,BIRC7,BRCA1,BUB1B,CDC20B,CDC23,CDC27,CHFR,CUL1,CUL3,DCUN1D4,FANCL,FBXL3,FBXL4,FBXO11,FBXO22,FBXO24,FBXO7,FBXW11,FZR1,G2E3,HACE1,HERC5,IPP,KBTBD6,KCTD10,KLHL13,KLHL20,KLHL24,KLHL3,KLHL40,KLHL5,KLHL7,LIMK1,LNX1,LONRF1,MAEA,MALT1,MARCH5,MARCH6,MDM2,MGRN1,MKRN1,NEDD4L,NSMCE1,PELI1,PIN1,PPIL2,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PSMD1,PSMD11,PSMD12,PSMD2,PSMD6,PSME3,PSME4,RBBP6,RBCK1,RCHY1,RFWD3,RNF13,RNF2,RNF208,RNF216,RNF220,RNF25,RNF4,RNF43,RNF6,RNF8,TCEB1,TRAF4,TRIM17,TRIM2,TRIM5,TRIM69,TRIP12,TTC3,UBA52,UBE2B,UBE2E1,UBE2E2,UBE2G1,UBE2G2,UBE2T,UBE2W,UBE3A,UBE3C,UBE4A,UBR4,WDSUB1,WSB1,WWP1,XIAP,ZNRF2 82.96 0.00013 0.007761 GO:0016787 hydrolase activity molecular_function 3691 803 ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABHD10,ABHD12B,ABHD3,ABR,ACAP1,ACAP2,ACE,ACIN1,ACOT8,ACOT9,ACP1,ACYP2,ADA,ADAD2,ADAM10,ADAM22,ADAM23,ADAM28,ADAM33,ADAMDEC1,ADAMTS10,ADAMTS6,ADAMTSL1,ADAMTSL3,ADAT2,ADCYAP1,ADGB,ADORA1,ADPRHL1,AEBP1,AGBL1,AGFG1,AGO1,AGO2,AGTPBP1,AHSA2,AIP,AK6,AKT1,ALKBH2,ALOX15,ALPL,ALPP,AMDHD2,AMPD3,AMPH,AMZ2,ANGPTL3,ANKLE2,ANXA2,ANXA4,APEX2,APH1A,APOBEC3B,APOBEC3F,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID4A,ARL1,ARL2BP,ARL8A,ARPP19,ARSA,ASAH1,ASPG,ATAD1,ATF7IP,ATG4B,ATIC,ATL2,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP5J2,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATRX,ATXN3,BAG4,BAP1,BAX,BCAS3,BCHE,BICD1,BIRC3,BIRC6,BIRC7,BMP2K,BMS1,BNIP2,BOK,BPNT1,BPTF,BRIP1,C12orf65,C1RL,C1S,C2,C4A,C4B,CA1,CABIN1,CALM1,CAMK2A,CAMK2G,CAMSAP3,CAPN13,CAPN8,CARD16,CASP4,CASP8,CCL25,CCZ1,CD2BP2,CD44,CDC14B,CDC42,CDC42EP3,CDK5RAP3,CDK7,CDKN3,CECR1,CEP192,CES1,CES4A,CFAP100,CFAP73,CFLAR,CHD1,CHD2,CHD3,CHD6,CHD7,CHID1,CHIT1,CHN1,CHTOP,CLU,CNDP2,CNOT2,CNOT7,CNOT8,CNST,COL4A3,COLEC11,CPA2,CPA5,CPA6,CPNE1,CPQ,CPS1,CPSF3L,CR1,CRBN,CRYAB,CSNK2A1,CSRNP3,CSTL1,CTDNEP1,CTDSPL2,CTRB1,CYLD,CYTH4,DAB2IP,DAPK1,DARS,DCTD,DCTN1,DCTN2,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DDX60L,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DESI2,DHX15,DHX40,DHX57,DIABLO,DICER1,DLG2,DLG3,DMC1,DMPK,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAI1,DNAI2,DNAJB11,DNAJC1,DNAJC10,DNAJC24,DNALI1,DNASE1,DNM1L,DNM3,DOCK4,DOCK7,DPEP2,DPEP3,DPP10,DPP3,DPYS,DQX1,DROSHA,DUSP13,DUSP16,DUSP9,DYNC1I2,DYNC1LI1,ECT2,EDEM3,EGF,EGFR,EHD2,EIF2AK2,EIF2S3,EIF3F,EIF4A1,EIF4A2,EIF4B,EIF4H,EIF5B,ELAC2,ELMOD3,ENGASE,ENOPH1,ENPP2,ENTPD4,ENTPD6,ENTPD8,EPHA4,EPS8L1,ERAP2,ERCC6L,ERCC6L2,ERI2,ERN2,ESD,ESR1,EXD1,EXD3,EXOSC8,EYA3,EYA4,EZH2,FADD,FAM135A,FAM13B,FAM76B,FARP1,FARP2,FAS,FGD3,FGD4,FGD6,FGF5,FGFR1,FIGNL1,FNBP1,FNBP1L,FNTA,FRS2,GALC,GARS,GBA2,GBP5,GCGR,GDA,GDI2,GDPD1,GEN1,GFRA2,GGH,GLA,GLB1L3,GLS,GLS2,GMIP,GMPS,GNA12,GNA14,GNGT1,GNL2,GNPAT,GNPDA2,GPC3,GPIHBP1,GPSM1,GSK3B,GSN,GTF2H2,GTF2H3,GTPBP10,GZMK,HACD3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,HDHD2,HELB,HELLS,HEXB,HLTF,HMGA2,HNRNPU,HSP90B1,HSPA8,HSPD1,HSPH1,HTR2B,HYAL1,HYAL3,IAH1,IL2RA,IMMP2L,INO80,INPP1,INPP5A,INPP5B,ITGA2,ITGA6,ITGB1BP1,ITSN2,KALRN,KEL,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KLK11,KLK12,KLK8,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LDAH,LIPJ,LLGL2,LMLN,LNPEP,LONRF1,LPIN1,LTA4H,LTF,LYG2,LYPLA1,MACROD2,MADD,MALT1,MAN1C1,MAN2A1,MAN2C1,MANEA,MANEAL,MAP1S,MAP2K5,MAPK8,MASTL,MBD3,MBTPS2,MCF2,MCF2L,MCM2,MCM8,MDM2,MEF2C,MEST,METAP2,METTL21A,MFN1,MGEA5,MMAA,MME,MMP19,MMP28,MNAT1,MPHOSPH10,MPPE1,MSTO1,MTA1,MTA3,MT-ATP6,MTCH1,MTG1,MTHFD1,MTHFD2L,MTIF2,MTMR1,MTMR7,MTOR,MUTYH,MYH10,MYH9,MYO10,MYO15B,MYO16,MYO18A,MYO1B,MYO1F,MYO1G,MYO3B,MYSM1,NADSYN1,NAGPA,NAPEPLD,NCK1,NDE1,NEU4,NF1,NIT2,NLGN3,NLRP12,NOS3,NPRL3,NRDC,NSMAF,NT5C2,NT5C3B,NT5DC1,NTAN1,NTPCR,NTRK2,NUDT21,NUDT6,NUDT9,OARD1,OCRL,OMA1,OPA1,OTUD4,OTULIN,OVOS2,P2RY12,PAFAH1B1,PAK2,PAN3,PARN,PAX2,PCOLCE2,PCSK5 725.57 0.00015 0.00873658536585366 GO:0008092 cytoskeletal protein binding molecular_function 836 206 ABI1,ABLIM2,ABLIM3,ACTN1,ACTR2,ACTR3C,ADD3,ADNP,AGBL1,AGTPBP1,ANK2,ANK3,ANLN,ANTXR1,ANXA2,AP1G1,APBB1,ARHGEF2,ARL8A,ARPC1A,ARPC1B,BCAS3,BICD1,BRCA1,CACNA1C,CALM1,CAMSAP3,CAPZA1,CCDC88A,CDC42EP3,CDH1,CENPJ,CEP290,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,CLIP1,CLIP2,COBL,CORO2B,CORO7,CRYAB,CTNNA1,CTNNA3,CYFIP1,DAAM1,DAG1,DCTN1,DCTN2,DES,DNASE1,DNM1L,DNM3,EGFR,EML2,EML4,EPB41L3,EPS8L1,EVL,FAM110C,FAM175B,FARP1,FARP2,FBLIM1,FES,FEZ1,FGD4,FHOD3,FKBP4,FLII,FMN1,FMN2,FMNL2,FNTA,FRMD3,FTCD,FUS,GCSAM,GLI1,GMFB,GMFG,GSN,HDAC6,HOOK1,HSPH1,IMPACT,INO80,IPP,KCNMA1,KCNN2,KIF13A,KIF15,KIF1A,KIF1BP,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KLHL20,KLHL3,KLHL5,KRIT1,KTN1,LCP1,LIMCH1,LRPPRC,LSP1,MAEA,MAGI1,MAP1LC3B,MAP1S,MAP2,MAP6,MAP6D1,MAPK8IP3,MDM1,MLPH,MYBPC1,MYH10,MYH9,MYLK,MYO10,MYO16,MYO18A,MYO1B,MYO1F,MYO1G,MYO3B,MYOC,MYOZ3,NCK1,NCKIPSD,NDE1,NEB,NOS3,NUSAP1,OFD1,OPA1,OPRM1,PAFAH1B1,PALLD,PARVG,PAWR,PDCD5,PDLIM2,PDLIM3,PFN2,PHF6,PICK1,PKNOX2,POLB,PPP1R42,PPP2R2A,PRC1,PROM1,PTK2,PTPRN,PXN,RAB27B,RACGAP1,RAE1,REEP1,RGS14,RP2,SDCBP,SGIP1,SHTN1,SIRT2,SMTN,SNTG2,SORBS2,SORBS3,SPAG8,SPAG9,SPTB,SPTBN1,SPTBN4,SSFA2,STMN4,SYNE1,SYNPO,SYNPO2,TLN1,TMEM67,TNNI3,TNNT1,TNNT2,TNS1,TOR1AIP1,TPGS1,TPPP3,TRIOBP,TRPM7,TTLL4,TUBGCP5,TWF1,USH1C,USH2A,VBP1,VEZT,VIL1,WDR43,ZNF207 164.34 0.00016 0.00909714285714286 GO:0016772 transferase activity, transferring phosp... molecular_function 1581 365 AAK1,AATK,ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADK,ADNP,ADORA1,ADPGK,AGK,AK2,AK6,AKT1,ALDH18A1,ALPK1,AMBRA1,ATP23,ATP2B4,ATR,AURKA,AURKB,BAX,BCCIP,BCKDK,BIRC7,BLK,BMP2K,BMPR1B,BRAF,BTK,BUB1B,CACUL1,CALM1,CAMK2A,CAMK2G,CASK,CCDC88A,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CDS2,CHAD,CHORDC1,CHRAC1,CHRNA3,CHRNA7,CHUK,CKMT2,CLK2,CMPK1,COASY,CPNE3,CRCP,CRLS1,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CTC1,CUX1,DAB2IP,DAPK1,DAPK3,DDR1,DDR2,DGKA,DGKG,DGKZ,DLG2,DLG3,DMPK,DNAJA1,DPAGT1,DTYMK,DUSP16,DUSP9,DYRK2,DYRK4,ECT2,EGF,EGFR,EIF2AK2,EIF4A2,ELP4,EPHA10,EPHA4,EPHB2,ERN2,ETNK1,EZH2,FAF1,FAM150A,FAM58A,FASTK,FBXO7,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FLAD1,FRS2,GADD45G,GAK,GMFB,GMFG,GNPTG,GPRC5B,GRHL2,GRK6,GSK3B,GSTP1,GTF2H2,GTF2H3,GUK1,H2AFY,HACD3,HERC5,HGS,HIPK3,HMGA2,HSPH1,HTR2B,IGF1R,IGF2R,IL1B,IP6K2,IRAK1,IRAK4,ITGB1BP1,KALRN,KAT2B,KRAS,KSR2,LAMTOR3,LAT,LIMK1,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MASTL,MED21,MELK,MIDN,MINK1,MKNK1,MNAT1,MST1R,MTOR,MVP,MYLK,MYO3B,NADK,NAGK,NCK1,NEK10,NEK11,NEK7,NF1,NLRC5,NME4,NME5,NME6,NME7,NME9,NMNAT3,NMRK1,NOX4,NRP2,NT5C2,NTRK2,NTRK3,NVL,OSBPL8,PAK1,PAK2,PAK3,PAN3,PANK1,PANK3,PANK4,PAPD4,PAPOLG,PAQR3,PBK,PCYT1A,PDCD10,PDE5A,PDGFRB,PDIK1L,PDK3,PDXK,PEAK1,PFKFB1,PHKA1,PIGN,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIP5K1A,PIP5K1C,PKDCC,PKM,PLK3,PLK4,PNKP,PNPT1,PODN,POLA1,POLA2,POLB,POLD3,POLD4,POLI,POLK,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,POT1,PPIP5K1,PPIP5K2,PPP1R1B,PPP2R1A,PPP2R3C,PPP4C,PRIM1,PRKAR2A,PRKCZ,PRLR,PRPF4B,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RANBP2,RAP1A,RAPGEF2,RBL1,RELN,REV1,RFC2,RFC4,RGN,RGS14,RGS3,RIOK3,ROS1,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RPS6KC1,RPS6KL1,RTN4RL2,SASH1,SCYL2,SGK1,SGMS1,SHC2,SMG1,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPEG,SPRY1,SRPK2,SRPK3,STK10,STK17A,STK25,STK32B,TAB2,TAB3,TARBP2,TBCK,TBK1,TCP1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TK1,TLK2,TLR9,TNFRSF10B,TNK2,TNKS,TOM1L1,TRAF4,TRIO,TRPM6,TRPM7,TTK,TWF1,TYK2,UBA52,UGP2,ULK2,UPRT,UVRAG,VAV1,VEGFA,WEE1,WNT11,WWTR1,YRDC,ZAP70,ZCCHC11,ZMYM2,ZP4 310.79 0.00021 0.0116623255813953 GO:0043167 ion binding molecular_function 6302 1324 AAK1,AATK,AATK-AS1,ABAT,ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ABCE1,ABLIM2,ABLIM3,ABR,ACACA,ACAD11,ACAD8,ACADVL,ACAP1,ACAP2,ACAT1,ACBD4,ACE,ACOX3,ACOXL,ACSBG1,ACSF3,ACSL1,ACSM6,ACSS3,ACTG1,ACTN1,ACTR2,ACTR3C,ADA,ADAM10,ADAM28,ADAM33,ADAMDEC1,ADAMTS10,ADAMTS6,ADAMTSL1,ADAMTSL3,ADAT2,ADCY10,ADCY4,ADIPOR1,ADIPOR2,ADK,ADNP,ADPGK,ADPRHL1,AEBP1,AGBL1,AGFG1,AGK,AGO2,AGTPBP1,AIFM3,AK2,AK6,AKT1,ALDH18A1,ALDH1A3,ALKBH2,ALOX15,ALPK1,ALPL,ALPP,AMD1,AMDHD2,AMER1,AMER3,AMPD3,AMPH,AMZ2,ANGPT2,ANGPTL3,ANKIB1,ANTXR1,ANXA2,ANXA4,ANXA6,ANXA7,APEX2,APLP1,APOBEC3B,APOBEC3F,APRT,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARID2,ARIH1,ARL1,ARL5C,ARL6,ARL8A,ARMC1,ARSA,ASH1L,ASNS,ASXL3,ATAD1,ATF2,ATL2,ATMIN,ATP11B,ATP11C,ATP1B1,ATP23,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP7B,ATP9B,ATR,ATRX,AURKA,AURKB,BAZ1A,BAZ2A,BCHE,BCKDK,BIN2,BIRC3,BIRC7,BLK,BMP2K,BMPR1B,BMS1,BNIP2,BPNT1,BPTF,BRAF,BRCA1,BRIP1,BSN,BTK,BUB1B,C1S,C2,C2CD5,CA1,CA12,CABYR,CACNA1A,CACNA1C,CACNA1H,CACNA1S,CACNA2D1,CACNA2D4,CADPS2,CALB1,CALM1,CALU,CAMK2A,CAMK2G,CAPN13,CAPN8,CAPS,CAPSL,CARMIL2,CARS,CASK,CBWD1,CBWD2,CCDC80,CCDC88A,CCT3,CCT7,CCZ1,CDC42,CDC6,CDH1,CDH13,CDH23,CDH26,CDH8,CDHR1,CDHR3,CDK11A,CDK12,CDK13,CDK17,CDK7,CDKAL1,CEACAM5,CECR1,CELSR1,CELSR2,CHD1,CHD2,CHD3,CHD6,CHD7,CHFR,CHMP3,CHN1,CHORDC1,CHRD,CHRNA3,CHRNA5,CHRNA6,CHRNA7,CHUK,CIB2,CIZ1,CKMT2,CLCN1,CLCN3,CLCNKA,CLIP1,CLK2,CMPK1,CNDP2,CNGA1,CNOT7,CNOT8,COASY,COX17,COX5A,CPA2,CPA5,CPA6,CPEB1,CPNE1,CPNE3,CPQ,CPS1,CPXCR1,CRACR2A,CRBN,CREB5,CRTAC1,CRYAB,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CUL9,CXXC4,CYB561,CYBB,CYLD,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP3A7-CYP3A51P,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,CYTH4,DAB2IP,DAG1,DALRD3,DAPK1,DAPK3,DARS,DARS2,DBF4,DBI,DCTD,DDR1,DDR2,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DDX60L,DENND1B,DENND1C,DENND4A,DENND4C,DGKA,DGKG,DGKZ,DHFR,DHX15,DHX40,DHX57,DICER1,DLD,DMC1,DMPK,DMRT2,DMRTA1,DNA2,DNAH10,DNAH11,DNAH17,DNAH2,DNAH3,DNAH9,DNAJA1,DNAJC21,DNAJC24,DNM1L,DNM3,DOCK4,DOCK7,DPEP2,DPEP3,DPF1,DPH3,DPP3,DPYS,DQX1,DRG1,DROSHA,DSG2,DTNA,DTX1,DTYMK,DYNC1LI1,DYRK2,DYRK4,DYSF,EBF4,ECT2,EDEM3,EEA1,EFCAB1,EFCAB14,EFCAB7,EFCC1,EFHB,EGF,EGFL7,EGFLAM,EGFR,EHD2,EHMT1,EHMT2,EIF2AK2,EIF2S3,EIF4A1,EIF4A2,EIF5B,ELAC2,ENO4,ENOPH1,ENOSF1,ENPP2,ENTPD8,EPHA10,EPHA4,EPHB2,EPRS,EPS8L1,ERAP2,ERCC6L,ERCC6L2,ERI2,ERN2,ESR1,ESRRB,ESRRG,ETFA,ETNK1,EXD3,EXOC1,EYA3,EYA4,FABP5,FAM96A,FANCL,FARP1,FARP2,FASTK,FAT1,FAXDC2,FBLIM1,FBLN2,FBLN5,FBN1,FBXO11,FCER2,FCHO2,FES,FGD3,FGD4,FGD6,FGF5,FGFR1,FHL1,FIGNL1,FKBP4,FKBP8,FLAD1,FNBP1,FNBP1L,FRAS1,FRMPD2,FRS2,FTCD,FUS,G2E3,GAK,GALNT11,GALNT14,GALNT16,GALNT2,GARS,GART,GATAD2A,GATAD2B,GBP5,GCAT,GCGR,GCLC,GDA,GDI2,GDPD1,GEN1,GFRA2,GGPS1,GLI1,GLRA3,GLRX2,GMIP,GMPS,GNA12,GNA14,GNL2,GPC1,GPC3,GPSM1,GRB7,GRK6,GRM7,GSK3B,GSN,GSTP1,GTF2B,GTF2H2,GTF2H3,GTPBP10,GUK1,GZF1,HARS,HAVCR2,HDAC6,HDAC7,HDAC8,HDAC9,HDC,HDHD2,HELB,HELLS,HGS,HIPK3,HIVEP3,HKR1,HLTF,HNRNPU,HPRT1,HSP90B1,HSPA14,HSPA8,HSPB11,HSPD1,HSPH1,HTR2B,IDO1,IGF1R,IGF2R,IL2RA,IMPDH1,INO80,INPP1,INPP5B,INTS12,IP6K2,IRAK1,IRAK4 1238.83 0.00028 0.0151963636363636 GO:0060589 nucleoside-triphosphatase regulator acti... molecular_function 604 153 ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,AHSA2,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL2BP,ATP1B1,BAG4,BNIP2,CALM1,CAMK2A,CAMK2G,CCZ1,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,ECT2,EGF,EGFR,ELMOD3,EPHA4,EPS8L1,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GPSM1,HACD3,HSPH1,HTR2B,IL2RA,INPP5B,ITGB1BP1,ITSN2,KALRN,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,NCK1,NF1,NPRL3,OCRL,P2RY12,PDE6D,PDGFRB,PFN2,PIK3R2,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGS14,RGS3,RGS6,RIC1,RIC8B,RIMS1,RP2,RPGR,RUNDC1,SBF1,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TNK2,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,USP6NL,VAV1,WNT11 118.73 0.00030 0.0155739130434783 GO:0043175 RNA polymerase core enzyme binding molecular_function 25 13 AGO1,AGO2,BRD4,C14orf166,CTR9,ELP2,ELP4,RECQL5,SMYD2,SMYD3,UVSSA,WAC,ZNF326 4.91 0.00030 0.0155739130434783 GO:0004712 protein serine/threonine/tyrosine kinase... molecular_function 98 34 ADORA1,AKT1,AURKA,AURKB,BRAF,CLK2,DAB2IP,DYRK2,DYRK4,EGF,EGFR,EIF2AK2,FRS2,GADD45G,IGF1R,LAMTOR3,MAP2K3,MAP2K4,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPKAPK5,PAK3,RAP1A,RELN,RPS6KA1,RPS6KB1,SGK1,TGFBR1,TNK2,TTK 19.26 0.00034 0.0165697959183673 GO:0003743 translation initiation factor activity molecular_function 51 21 AGO2,EIF1,EIF2A,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,MCTS1,MTIF2,MTIF3 10.03 0.00034 0.0165697959183673 GO:0019213 deacetylase activity molecular_function 65 25 AMDHD2,ARID4A,CES1,CHD3,ESD,FNTA,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MACROD2,MAPK8,MBD3,MTA1,MTA3,OARD1,PHF21A,RBBP4,RBBP7,SAP18,SIRT2,SIRT6,VEGFA 12.78 0.00034 0.0165697959183673 GO:0003729 mRNA binding molecular_function 169 52 AGO2,ANGEL2,BOLL,C1QBP,CPEB1,CPEB3,CPSF6,CSTF3,DDX1,DHFR,EDC3,EIF4A1,ESRP1,FXR1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,IGF2BP3,LUC7L,LUC7L3,METTL14,MRPL13,MRPS11,NCBP2,NCBP3,NUDT21,NXF3,PABPC1,PAIP2,PARN,PCBP4,PTBP2,PUM2,PUM3,RBM25,RBM4,RBMX,RBPMS,RNPS1,RPS2,RPS5,SERBP1,SF3B1,SSB,THOC2,TIA1,TRA2B,TYMS,YBX3,ZC3H12A,ZNF385A 33.22 0.00036 0.0168564705882353 GO:0044822 poly(A) RNA binding molecular_function 169 52 AGO2,ANGEL2,BOLL,C1QBP,CPEB1,CPEB3,CPSF6,CSTF3,DDX1,DHFR,EDC3,EIF4A1,ESRP1,FXR1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,IGF2BP3,LUC7L,LUC7L3,METTL14,MRPL13,MRPS11,NCBP2,NCBP3,NUDT21,NXF3,PABPC1,PAIP2,PARN,PCBP4,PTBP2,PUM2,PUM3,RBM25,RBM4,RBMX,RBPMS,RNPS1,RPS2,RPS5,SERBP1,SF3B1,SSB,THOC2,TIA1,TRA2B,TYMS,YBX3,ZC3H12A,ZNF385A 33.22 0.00036 0.0168564705882353 GO:0003950 NAD+ ADP-ribosyltransferase activity molecular_function 29 14 ART3,HMGN1,PARP10,PARP12,PARP14,PARP2,PARP6,PARP8,SIRT2,SIRT5,SIRT6,TGFB1,TIPARP,TNKS 5.7 0.00048 0.0220430769230769 GO:0008270 zinc ion binding molecular_function 1131 265 ABLIM2,ABLIM3,ACE,ADA,ADAM33,ADAMDEC1,ADAMTS10,ADAMTS6,ADAMTSL1,ADAMTSL3,ADAT2,AEBP1,AGBL1,AGTPBP1,ALPP,AMZ2,ANKIB1,APEX2,APOBEC3B,APOBEC3F,ARHGEF2,ARIH1,ASH1L,BAZ1A,BAZ2A,BIRC3,BIRC7,BPTF,BRCA1,CA1,CA12,CALB1,CECR1,CHD3,CHFR,CHORDC1,CIZ1,CLIP1,CNDP2,CPA2,CPA5,CPA6,CUL9,CXXC4,CYLD,DBF4,DCTD,DNAJC21,DNAJC24,DPF1,DPP3,DPYS,DTNA,DTX1,EEA1,EHMT1,EHMT2,ENPP2,ERAP2,ERI2,ESR1,ESRRB,ESRRG,FBLIM1,FBXO11,FHL1,FUS,G2E3,GATAD2A,GATAD2B,GDA,GTF2B,GTF2H2,HDAC6,HLTF,INTS12,JADE1,KAT6A,KAT7,KDM1B,KDM5D,KDM7A,KMT2A,KMT2D,KMT2E,L3MBTL1,LHX6,LHX9,LIG3,LIMCH1,LIMD1,LIMD2,LIMK1,LIMS2,LIMS3,LMO2,LMO3,LNPEP,LNX1,LONRF1,LPP,LTA4H,LTN1,MAN2A1,MAN2C1,MARCH5,MARCH6,MBTD1,MDM2,MDM4,MGRN1,MKRN1,MKRN3,MME,MMP19,MMP28,MNAT1,MTA1,MTA3,MTF2,MYNN,NAPEPLD,NPLOC4,NR2C1,NR3C1,NR3C2,NRDC,NSMCE1,NSMCE2,PCGF3,PDLIM2,PDLIM3,PDLIM7,PDXK,PGLYRP2,PHC3,PHF1,PHF11,PHF12,PHF14,PHF20,PHF21A,PHF21B,PHF6,PIAS1,PMPCB,POLR2I,POLR2K,PRICKLE1,PTGR2,PXN,RABGGTB,RAD18,RANBP2,RAPSN,RBBP6,RBCK1,RBM4,RCHY1,RFWD3,RGN,RLF,RNF121,RNF13,RNF138,RNF14,RNF150,RNF166,RNF183,RNF2,RNF208,RNF212,RNF219,RNF220,RNF25,RNF32,RNF4,RNF43,RNF44,RNF6,RNF8,RNFT1,RORC,RXRA,SCAF11,SEC23B,SEC24A,SEC24B,SEC24D,SF1,SIRT2,SIRT5,SIRT6,SLC30A5,SOD3,SPG7,SREK1IP1,SRSF7,ST18,SUPT4H1,TAB2,TAB3,TAF15,TAF2,TCEA2,TCF20,TGFB1I1,TK1,TNKS,TRAF4,TRIM17,TRIM2,TRIM29,TRIM38,TRIM41,TRIM43,TRIM5,TRIM69,TRIM73,TRIP6,TTC3,UBR4,UQCRC2,USP3,USP33,USP39,VPS11,VPS8,WHSC1,WHSC1L1,XIAP,ZCCHC11,ZCCHC13,ZCCHC17,ZCCHC8,ZDHHC16,ZDHHC17,ZDHHC4,ZDHHC8,ZEB1,ZFR,ZGRF1,ZMAT4,ZMYM1,ZMYM2,ZMYM5,ZNF195,ZNF2,ZNF207,ZNF208,ZNF253,ZNF257,ZNF276,ZNF330,ZNF385A,ZNF638,ZNF84,ZNF91,ZNF92,ZNRF2,ZRANB2,ZRANB3,ZSWIM8,ZYX,ZZZ3 222.33 0.00065 0.0291866666666667 GO:0044389 ubiquitin-like protein ligase binding molecular_function 282 78 ABTB1,ACTG1,AKTIP,AMBRA1,ARIH1,ASB15,ATXN3,AURKA,BAG4,BCL2,BLZF1,BRCA1,BTBD2,BTBD9,CACUL1,CASP8,CDK5RAP3,CLU,CUL1,CUL3,CUL4B,CUL9,DBT,DLG3,DNAJA1,DNM1L,DTX1,EGFR,FAF1,FANCL,FBXO7,FZD6,GSK3B,HDAC6,HLTF,HSPA8,HSPD1,JKAMP,LRPPRC,MAP1LC3B,MDM2,NAE1,NPLOC4,PCBP2,PIAS1,PRKAR2A,PRR5L,PTPRN,RAD18,RALB,RNF8,SLF1,SMAD2,SMC6,SNX9,STX8,SUMO1,SUMO2,TANK,TCP1,TMBIM6,TMEM189,TPI1,TRAF4,TRIOBP,UBE2B,UBE2F,UBE2G1,UBE2G2,UBE2J2,UBE2T,UBE2V1,UBE2W,UBE2Z,USP25,USP7,XRCC5,YWHAZ 55.43 0.00066 0.0291866666666667 GO:0008135 translation factor activity, RNA binding molecular_function 90 31 ABTB1,AGO2,C12orf65,CPEB1,CPEB3,EEF1B2,EEF1D,EIF1,EIF2A,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,GTF2H2,GTF2H3,MCTS1,MTIF2,MTIF3,MTRF1,MTRF1L 17.69 0.00069 0.0299585454545455 GO:0003676 nucleic acid binding molecular_function 3362 727 ABTB1,ACIN1,ACTL6A,ACTN1,ADAD2,ADNP,AEBP1,AFF3,AGFG1,AGO1,AGO2,AHCTF1,AHR,AKAP1,AKNA,ANGEL2,APEX2,APOBEC3F,ARID1B,ARID2,ARID4A,ARPP21,ASH1L,ASXL3,ATF2,ATF4,ATMIN,ATOH8,ATR,ATRX,ATXN2,BAHCC1,BANP,BATF2,BAZ2A,BBX,BCL2,BCLAF1,BLZF1,BMS1,BOLL,BPTF,BRCA1,BRD7,BRIP1,C12orf65,C14orf166,C1D,C1QBP,CALM1,CAMTA1,CAPRIN1,CARF,CARS,CCNT1,CCNT2,CENPA,CENPC,CERS2,CHD1,CHD2,CHD3,CHD6,CHD7,CHRAC1,CHTOP,CIART,CIZ1,CLTC,CNOT7,CNOT8,COA1,CPEB1,CPEB3,CPNE1,CPSF6,CRAMP1,CREB5,CREM,CRNKL1,CSDE1,CSRNP3,CSTF1,CSTF3,CTC1,CUL4B,CUX1,CWC22,CXXC4,DARS2,DBF4,DDB1,DDX1,DDX20,DDX39B,DDX60L,DENND4A,DHFR,DHX15,DICER1,DMC1,DMRT2,DMRTA1,DMTF1,DNA2,DNAJC1,DOT1L,DR1,DROSHA,E2F5,E2F7,EAF2,EBF4,EDC3,EEF1B2,EEF1D,EGF,EGFR,EHD2,EIF1,EIF2A,EIF2AK2,EIF2S3,EIF3B,EIF3D,EIF3F,EIF3J,EIF3M,EIF4A1,EIF4A2,EIF4B,EIF4E,EIF4G2,EIF4G3,EIF4H,EIF5B,EIF6,ELF1,ELF3,EMX1,EN1,ENOX1,ENPP2,EPRS,ERCC6L,ERCC6L2,ERI2,ESR1,ESRP1,ESRRB,ESRRG,ETV1,ETV5,ETV6,ETV7,EXD1,EXD3,EXOSC8,EZH2,FAM200B,FANCI,FASTK,FBL,FOXJ1,FOXN3,FOXN4,FOXR1,FUBP1,FUS,FXR1,GABPB1,GATAD2A,GATAD2B,GEN1,GLI1,GPATCH1,GPBP1,GPBP1L1,GRB7,GRHL1,GRHL2,GTF2B,GTF2H2,GTF2H3,GTF2H5,GTF2I,GTF3C2,GTF3C3,GTF3C5,GZF1,H2AFV,H2AFY,HDAC1,HDAC2,HDAC6,HEATR1,HESX1,HEYL,HIST1H2BN,HIST2H2AC,HIVEP3,HKR1,HLTF,HMGA2,HMGN1,HNRNPA2B1,HNRNPA3,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPM,HNRNPU,HOXA10,HOXA13,HOXA7,HOXA9,HOXB1,HOXC4,HOXC9,HOXD11,HSF4,HSP90B1,HSPD1,IGF2BP3,IMPDH1,INO80,IRF2,IRF5,IRX4,ITGA2,JAZF1,JMJD1C,JMJD6,JUND,KANSL1,KANSL1L,KAT2B,KAT6A,KDM1B,KDM5D,KDM6A,KHDRBS3,KIF15,KLF16,KLF6,KMT2A,KMT2D,KRBOX4,LBR,LBX1,LCORL,LHX6,LHX9,LIG3,LIG4,LIN54,LMO2,LRPPRC,LSM5,LSM6,LSM8,LTF,LUC7L,LUC7L3,LYL1,MAFK,MAP1S,MBD3,MBD5,MBNL1,MCM2,MCM8,MCTS1,MEF2A,MEF2C,MEIS2,METTL1,METTL14,METTL5,MGA,MIER1,MIS18BP1,MKI67,MLF1,MLX,MLXIP,MRPL1,MRPL13,MRPS11,MRPS6,MSH5,MSI1,MSI2,MSX2,MTA1,MTA3,MTDH,MTF2,MTIF2,MTIF3,MTOR,MTRF1,MTRF1L,MUTYH,MXD3,MYB,MYF6,MYNN,MYO18A,MYSM1,NACA,NARS,NCBP2,NCBP3,NCOA1,NCOA2,NCOR1,NCOR2,NFATC1,NFE2L1,NFE2L2,NFE2L3,NFYA,NKRF,NKX1-1,NLRC5,NOL4,NOM1,NOP10,NOP56,NOP58,NPAS3,NR2C1,NR3C1,NR3C2,NSUN4,NSUN7,NUCB1,NUCB2,NUCKS1,NUDT21,NUP35,NUP98,NUSAP1,NXF3,ONECUT2,ORC4,PABPC1,PABPN1,PAIP2,PAPOLG,PARN,PARP2,PARPBP,PAX2,PAX3,PAX4,PAX7,PAXBP1,PBX1,PCBP2,PCBP3,PCBP4,PDCD2,PDCD5,PDS5B,PHC3,PHF12,PHF20,PHF21A,PHF21B,PHF6,PHTF2,PIAS1,PIWIL4,PKNOX2,PMS1,PMS2,PNKP,PNLDC1,PNPT1,POLA1,POLA2,POLB,POLI,POLK,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POT1,POU2F2,PPIE,PPP1R8,PRDM16,PREB,PRMT1,PRMT5,PRPF39,PRPF40A,PRRX1,PSIP1,PSMA1,PSMA6,PTBP2,PTCD3,PUM2,PUM3,PURA,PURG,RAD17,RAD18,RAD51AP1,RAD51C,RAD52,RAD54B,RAD54L,RAD54L2,RAE1,RANBP2,RARS,RBBP4,RBBP7,RBBP8,RBM11,RBM23,RBM25,RBM4,RBM41,RBM45,RBM48,RBM7,RBMS1,RBMS2,RBMX,RBMX2,RBMXL1,RBPJ,RBPMS,RCL1,RDM1,RECQL5,REV1,REXO2,RFC2,RFC4,RFX2,RFX5,RFX7,RLF,RNASET2,RNF138,RNF4,RNF6,RNPS1,RORC,RPA3,RPF1,RPF2,RPL13,RPL14,RPL18A,RPL22,RPL23,RPL26,RPL27A,RPL31,RPL35A,RPL37,RPL4,RPL5,RPL6,RPL8,RPLP0,RPS2,RPS5,RPUSD1,RUNX1T1,RXRA,SART3,SCAF1,SERBP1,SERPINA3,SF1,SF3B1,SF3B3,SFPQ,SIDT2,SIM1,SIM2,SIRT2,SIX1,SIX3 660.9 0.00073 0.0311292857142857 GO:0031625 ubiquitin protein ligase binding molecular_function 276 76 ABTB1,ACTG1,AKTIP,AMBRA1,ARIH1,ASB15,ATXN3,AURKA,BAG4,BCL2,BLZF1,BRCA1,BTBD2,BTBD9,CACUL1,CASP8,CLU,CUL1,CUL3,CUL4B,CUL9,DBT,DLG3,DNAJA1,DNM1L,DTX1,EGFR,FAF1,FANCL,FBXO7,FZD6,GSK3B,HDAC6,HLTF,HSPA8,HSPD1,JKAMP,LRPPRC,MAP1LC3B,MDM2,NAE1,NPLOC4,PCBP2,PIAS1,PRKAR2A,PRR5L,RAD18,RALB,RNF8,SLF1,SMAD2,SMC6,SNX9,STX8,SUMO1,SUMO2,TANK,TCP1,TMBIM6,TMEM189,TPI1,TRAF4,TRIOBP,UBE2B,UBE2F,UBE2G1,UBE2G2,UBE2J2,UBE2T,UBE2V1,UBE2W,UBE2Z,USP25,USP7,XRCC5,YWHAZ 54.26 0.00088 0.0368673684210526 GO:0004386 helicase activity molecular_function 163 49 ATRX,BRIP1,CHD1,CHD2,CHD3,CHD6,CHD7,CHTOP,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DDX60L,DHX15,DHX40,DHX57,DICER1,DNA2,DQX1,EIF4A1,EIF4A2,EIF4B,EIF4H,ERCC6L,ERCC6L2,HELB,HELLS,HLTF,INO80,MCM2,MCM8,POT1,RAD54B,RAD54L,RAD54L2,RECQL5,SMARCA2,SMARCA5,SMARCAD1,SSBP1,WRN,XRCC5,ZRANB3 32.04 0.00094 0.0387020689655172 GO:0030695 GTPase regulator activity molecular_function 574 143 ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,AMPH,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL2BP,BNIP2,CALM1,CAMK2A,CAMK2G,CCZ1,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DOCK4,DOCK7,ECT2,EGF,EGFR,ELMOD3,EPHA4,EPS8L1,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GMIP,GPSM1,HACD3,HTR2B,IL2RA,INPP5B,ITGB1BP1,ITSN2,KALRN,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,NCK1,NF1,NPRL3,OCRL,P2RY12,PDE6D,PDGFRB,PIK3R2,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGS14,RGS3,RGS6,RIC1,RIC8B,RIMS1,RP2,RPGR,RUNDC1,SBF1,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TNK2,TRIO,TRIP10,USP6NL,VAV1,WNT11 112.84 0.00099 0.0400698305084746 GO:0016773 phosphotransferase activity, alcohol gro... molecular_function 1304 299 AAK1,AATK,ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADK,ADNP,ADORA1,ADPGK,AGK,AKT1,ALPK1,ATP23,ATP2B4,ATR,AURKA,AURKB,BAX,BCCIP,BCKDK,BIRC7,BLK,BMP2K,BMPR1B,BRAF,BTK,BUB1B,CACUL1,CALM1,CAMK2A,CAMK2G,CASK,CCDC88A,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CHAD,CHORDC1,CHRNA3,CHRNA7,CHUK,CLK2,COASY,CPNE3,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CUX1,DAB2IP,DAPK1,DAPK3,DDR1,DDR2,DGKA,DGKG,DGKZ,DMPK,DNAJA1,DUSP16,DUSP9,DYRK2,DYRK4,ECT2,EGF,EGFR,EIF2AK2,ELP4,EPHA10,EPHA4,EPHB2,ERN2,ETNK1,EZH2,FAF1,FAM150A,FAM58A,FASTK,FBXO7,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FRS2,GADD45G,GAK,GMFB,GMFG,GPRC5B,GRK6,GSK3B,GSTP1,GTF2H2,GTF2H3,H2AFY,HACD3,HERC5,HGS,HIPK3,HMGA2,HSPH1,HTR2B,IGF1R,IGF2R,IL1B,IP6K2,IRAK1,IRAK4,ITGB1BP1,KALRN,KAT2B,KRAS,KSR2,LAMTOR3,LAT,LIMK1,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MASTL,MELK,MIDN,MINK1,MKNK1,MNAT1,MST1R,MTOR,MVP,MYLK,MYO3B,NADK,NAGK,NCK1,NEK10,NEK11,NEK7,NF1,NMRK1,NOX4,NRP2,NT5C2,NTRK2,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PAN3,PANK1,PANK3,PANK4,PAQR3,PBK,PDCD10,PDE5A,PDGFRB,PDIK1L,PDK3,PDXK,PEAK1,PFKFB1,PHKA1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIP5K1A,PIP5K1C,PKDCC,PKM,PLK3,PLK4,PNKP,PODN,PPP1R1B,PPP2R1A,PPP2R3C,PPP4C,PRKAR2A,PRKCZ,PRLR,PRPF4B,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RANBP2,RAP1A,RAPGEF2,RELN,RGN,RGS14,RGS3,RIOK3,ROS1,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RPS6KC1,RPS6KL1,RTN4RL2,SASH1,SCYL2,SGK1,SHC2,SMG1,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPEG,SPRY1,SRPK2,SRPK3,STK10,STK17A,STK25,STK32B,TAB2,TAB3,TARBP2,TBCK,TBK1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TLK2,TLR9,TNFRSF10B,TNK2,TOM1L1,TRAF4,TRIO,TRPM6,TRPM7,TTK,TWF1,TYK2,UBA52,ULK2,UVRAG,VAV1,VEGFA,WEE1,WNT11,WWTR1,ZAP70,ZMYM2,ZP4 256.34 0.00126 0.050148 GO:0005388 calcium-transporting ATPase activity molecular_function 16 9 ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,RGN,RYR2,SUMO1,TLR9 3.15 0.00129 0.0504561290322581 GO:0043021 ribonucleoprotein complex binding molecular_function 97 32 ABCE1,C12orf65,C1QBP,CD2BP2,CPEB1,CPEB3,EIF2A,EIF4B,EIF4H,EIF6,EZH2,HNRNPU,IMPACT,LETM2,LETMD1,MALSU1,MTIF2,MTIF3,MTOR,MTRF1,MTRF1L,NAA10,NAA16,PHF6,PRMT5,PTCD3,RPN2,SMG6,SNRPB2,TIMM50,WDR12,ZC3H12A 19.07 0.00131 0.0504561290322581 GO:0016301 kinase activity molecular_function 1411 321 AAK1,AATK,ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADK,ADNP,ADORA1,ADPGK,AGK,AK2,AK6,AKT1,ALDH18A1,ALPK1,AMBRA1,ATP23,ATP2B4,ATR,AURKA,AURKB,BAX,BCCIP,BCKDK,BIRC7,BLK,BMP2K,BMPR1B,BRAF,BTK,BUB1B,CACUL1,CALM1,CAMK2A,CAMK2G,CASK,CCDC88A,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CHAD,CHORDC1,CHRNA3,CHRNA7,CHUK,CKMT2,CLK2,CMPK1,COASY,CPNE3,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CUX1,DAB2IP,DAPK1,DAPK3,DDR1,DDR2,DGKA,DGKG,DGKZ,DLG2,DLG3,DMPK,DNAJA1,DTYMK,DUSP16,DUSP9,DYRK2,DYRK4,ECT2,EGF,EGFR,EIF2AK2,ELP4,EPHA10,EPHA4,EPHB2,ERN2,ETNK1,EZH2,FAF1,FAM150A,FAM58A,FASTK,FBXO7,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FRS2,GADD45G,GAK,GMFB,GMFG,GPRC5B,GRK6,GSK3B,GSTP1,GTF2H2,GTF2H3,GUK1,H2AFY,HACD3,HERC5,HGS,HIPK3,HMGA2,HSPH1,HTR2B,IGF1R,IGF2R,IL1B,IP6K2,IRAK1,IRAK4,ITGB1BP1,KALRN,KAT2B,KRAS,KSR2,LAMTOR3,LAT,LIMK1,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MASTL,MELK,MIDN,MINK1,MKNK1,MNAT1,MST1R,MTOR,MVP,MYLK,MYO3B,NADK,NAGK,NCK1,NEK10,NEK11,NEK7,NF1,NLRC5,NME4,NME5,NME6,NME7,NME9,NMRK1,NOX4,NRP2,NT5C2,NTRK2,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PAN3,PANK1,PANK3,PANK4,PAQR3,PBK,PDCD10,PDE5A,PDGFRB,PDIK1L,PDK3,PDXK,PEAK1,PFKFB1,PHKA1,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R5,PIP5K1A,PIP5K1C,PKDCC,PKM,PLK3,PLK4,PNKP,PODN,PPIP5K1,PPIP5K2,PPP1R1B,PPP2R1A,PPP2R3C,PPP4C,PRKAR2A,PRKCZ,PRLR,PRPF4B,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RANBP2,RAP1A,RAPGEF2,RBL1,RELN,RGN,RGS14,RGS3,RIOK3,ROS1,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RPS6KC1,RPS6KL1,RTN4RL2,SASH1,SCYL2,SGK1,SGMS1,SHC2,SMG1,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPEG,SPRY1,SRPK2,SRPK3,STK10,STK17A,STK25,STK32B,TAB2,TAB3,TARBP2,TBCK,TBK1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TK1,TLK2,TLR9,TNFRSF10B,TNK2,TOM1L1,TRAF4,TRIO,TRPM6,TRPM7,TTK,TWF1,TYK2,UBA52,ULK2,UPRT,UVRAG,VAV1,VEGFA,WEE1,WNT11,WWTR1,ZAP70,ZMYM2,ZP4 277.37 0.00142 0.0538247619047619 GO:0016811 hydrolase activity, acting on carbon-nit... molecular_function 94 31 AMDHD2,ARID4A,ASAH1,ASPG,CHD3,DARS,GLS,GLS2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MTA1,MTA3,NADSYN1,NIT2,NTAN1,PGLYRP2,PHF21A,RBBP4,RBBP7,SAP18,SIRT2,SIRT5,SIRT6,VEGFA,WDYHV1 18.48 0.00156 0.0576793846153846 GO:0015631 tubulin binding molecular_function 290 78 ADNP,AGBL1,AGTPBP1,ARHGEF2,ARL8A,BCAS3,BRCA1,CAMSAP3,CCDC88A,CENPJ,CEP290,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,CLIP1,CLIP2,CRYAB,DAG1,DCTN1,DNM1L,DNM3,EML2,EML4,FAM110C,FAM175B,FES,FEZ1,FMN1,FNTA,FTCD,GLI1,HDAC6,HOOK1,HSPH1,INO80,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KRIT1,LRPPRC,MAP1LC3B,MAP1S,MAP2,MAP6,MAP6D1,MDM1,NDE1,NUSAP1,OFD1,OPA1,PAFAH1B1,PDCD5,PHF6,POLB,PPP1R42,PRC1,RACGAP1,RAE1,REEP1,RGS14,SGIP1,SIRT2,SPAG8,STMN4,TPGS1,TPPP3,TTLL4,TUBGCP5,VBP1,WDR43,ZNF207 57.01 0.00157 0.0576793846153846 GO:0008094 DNA-dependent ATPase activity molecular_function 83 28 ATRX,BPTF,BRIP1,CDK7,CHD1,CHD2,CHD3,CHD6,DMC1,DNA2,GTF2H2,GTF2H3,HELB,HNRNPU,MNAT1,RAD17,RAD18,RAD51C,RAD54B,RBBP4,RECQL5,RFC2,RFC4,SMARCA2,TOP2B,WRN,XRCC3,XRCC5 16.32 0.00176 0.06368 GO:0004672 protein kinase activity molecular_function 1179 271 AAK1,AATK,ABI1,ACE,ACSL1,ADCY4,ADCYAP1,ADNP,ADORA1,AKT1,ALPK1,ATP23,ATP2B4,ATR,AURKA,AURKB,BAX,BCCIP,BCKDK,BIRC7,BLK,BMP2K,BMPR1B,BRAF,BTK,BUB1B,CACUL1,CALM1,CAMK2A,CAMK2G,CASK,CCDC88A,CCNB2,CCNC,CCNE2,CCNG1,CCNL2,CCNT1,CCNT2,CD74,CD81,CDC42,CDC6,CDK11A,CDK12,CDK13,CDK17,CDK5RAP3,CDK7,CDKN3,CHAD,CHORDC1,CHRNA3,CHRNA7,CHUK,CLK2,CPNE3,CSF1R,CSNK1G1,CSNK2A1,CSNK2A2,CSNK2A3,CUX1,DAB2IP,DAPK1,DAPK3,DDR1,DDR2,DMPK,DNAJA1,DUSP16,DUSP9,DYRK2,DYRK4,ECT2,EGF,EGFR,EIF2AK2,ELP4,EPHA10,EPHA4,EPHB2,ERN2,EZH2,FAF1,FAM150A,FAM58A,FASTK,FBXO7,FES,FGF5,FGFR1,FGFR1OP,FGFR1OP2,FRS2,GADD45G,GAK,GMFB,GMFG,GPRC5B,GRK6,GSK3B,GSTP1,GTF2H2,GTF2H3,H2AFY,HACD3,HERC5,HGS,HIPK3,HMGA2,HSPH1,HTR2B,IGF1R,IGF2R,IL1B,IRAK1,IRAK4,ITGB1BP1,KALRN,KAT2B,KRAS,KSR2,LAMTOR3,LAT,LIMK1,LRP6,LRRTM1,LRRTM3,LTBP1,LTF,MADD,MAGED1,MALT1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MARK1,MARK3,MASTL,MELK,MINK1,MKNK1,MNAT1,MST1R,MTOR,MVP,MYLK,MYO3B,NCK1,NEK10,NEK11,NEK7,NF1,NOX4,NRP2,NTRK2,NTRK3,OSBPL8,PAK1,PAK2,PAK3,PAN3,PAQR3,PBK,PDCD10,PDE5A,PDGFRB,PDIK1L,PDK3,PEAK1,PHKA1,PIK3C3,PIK3CA,PIK3CB,PIK3R5,PKDCC,PLK3,PLK4,PODN,PPP1R1B,PPP2R1A,PPP2R3C,PPP4C,PRKAR2A,PRKCZ,PRLR,PRPF4B,PTEN,PTK2,PTK2B,PTPN2,PTPN6,RAC2,RALB,RAP1A,RAPGEF2,RELN,RGN,RGS14,RGS3,RIOK3,ROS1,RPS6KA1,RPS6KA6,RPS6KB1,RPS6KB2,RPS6KC1,RPS6KL1,RTN4RL2,SASH1,SCYL2,SGK1,SHC2,SMG1,SMYD3,SNX9,SORL1,SPAG9,SPDYA,SPEG,SPRY1,SRPK2,SRPK3,STK10,STK17A,STK25,STK32B,TAB2,TAB3,TARBP2,TBCK,TBK1,TELO2,TEX14,TGFA,TGFB1,TGFBR1,THY1,TLK2,TLR9,TNFRSF10B,TNK2,TOM1L1,TRAF4,TRIO,TRPM6,TRPM7,TTK,TWF1,TYK2,UBA52,ULK2,UVRAG,VEGFA,WEE1,WNT11,WWTR1,ZAP70,ZMYM2,ZP4 231.77 0.00184 0.0655808955223881 GO:0008134 transcription factor binding molecular_function 497 124 AHR,AIP,ANXA4,APBB1,APBB2,ARHGEF2,ATF2,ATF4,ATOH8,BBS1,BBS2,BCAS3,BCL2,BPTF,BRD7,C1QBP,CAND1,CBX5,CCNT1,CCNT2,CDK5RAP3,CHD6,CNOT2,CPNE1,CREM,CTBP1,DAPK3,DDX20,DNAJA1,DR1,DRG1,E2F5,EIF4E,ENPP2,ESR1,ESRRB,FAF1,FBL,FUS,GPX3,GSK3B,GTF2B,HDAC1,HDAC2,HDAC7,HDAC8,HDAC9,HEYL,HMGA2,HNRNPD,HOXA7,HYAL1,JMJD1C,JUND,KAT2B,KAT6A,LMO2,MAFK,MED13,MED14,MED16,MED24,MED30,MEF2A,MEF2C,MEIS2,MLX,MSX2,MTA1,MTDH,MTOR,NAB1,NCOA1,NCOA2,NCOA6,NCOR1,NCOR2,NFATC1,NFE2L2,NFKBID,NIF3L1,NOP58,NUCKS1,PAX2,PAXBP1,PHF12,PIAS1,PRDM16,PSMA6,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,PTPRN,PURA,RBBP8,RBL1,RBPJ,RNF25,RNF4,RXRA,SIRT2,SIX3,SKIL,SMAD2,SMAD4,SORBS3,SP1,SRI,SUMO1,TAF1B,TBX20,TBX3,TCERG1,TCF12,THRAP3,TRIP12,TRIP6,TSC22D3,UBA2,USP7,YWHAZ,ZEB1 97.7 0.00196 0.0688305882352941 GO:0042623 ATPase activity, coupled molecular_function 323 85 ABCA2,ABCA5,ABCB1,ABCB4,ABCB7,ABCB8,ABCC6,ATAD1,ATP11B,ATP11C,ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP5B,ATP5E,ATP5G3,ATP5H,ATP6V0A4,ATP6V0D1,ATP6V1C2,ATP7B,ATP9B,ATRX,BPTF,BRIP1,CDK7,CHD1,CHD2,CHD3,CHD6,CRBN,DDX1,DDX18,DDX20,DDX23,DDX24,DDX39B,DDX42,DDX47,DDX56,DDX6,DHX15,DHX40,DHX57,DMC1,DNA2,DQX1,EIF4A1,EIF4A2,ERCC6L2,FIGNL1,GTF2H2,GTF2H3,HELB,HNRNPU,HSPA8,LONRF1,MNAT1,MYH10,MYH9,MYO10,MYO1B,PCYOX1,RAD17,RAD18,RAD51C,RAD54B,RBBP4,RECQL5,RFC2,RFC4,RGN,RYR2,SMARCA2,SPG7,SUMO1,TLR9,TOP2B,VPS4A,WRN,XRCC3,XRCC5 63.49 0.00199 0.0688713043478261 GO:0016922 ligand-dependent nuclear receptor bindin... molecular_function 20 10 BAZ2A,C1D,JUND,NCOA1,NCOA2,NCOR1,NCOR2,SLC30A9,SMARCE1,UBA3 3.93 0.00225 0.0763487323943662 GO:0035091 phosphatidylinositol binding molecular_function 203 57 AKT1,ALOX15,AMER1,AMER3,ANXA2,ARAP2,ARHGAP33,BTK,CCDC88A,CEACAM5,DAB2IP,EEA1,EXOC1,FCHO2,FES,FRMPD2,GRB7,ITPR1,KRIT1,LANCL2,LDLRAP1,MARK1,MCF2L,MITD1,MPPE1,MYO10,MYO1B,MYO1G,NISCH,OGT,OSBPL5,OSBPL8,PFN2,PHF12,PLCB1,PLD1,PLEKHA4,RACGAP1,RPS6KC1,SH3YL1,SNAP91,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SYT1,SYT5,SYTL2,THY1,TWF1,VIL1,VPS36,WDR45B,ZFYVE16 39.91 0.00227 0.0763487323943662 GO:0046914 transition metal ion binding molecular_function 1374 311 ABCE1,ABLIM2,ABLIM3,ACE,ADA,ADAM33,ADAMDEC1,ADAMTS10,ADAMTS6,ADAMTSL1,ADAMTSL3,ADAT2,ADCY10,ADNP,AEBP1,AGBL1,AGTPBP1,ALKBH2,ALOX15,ALPP,AMZ2,ANKIB1,APEX2,APLP1,APOBEC3B,APOBEC3F,ARHGEF2,ARIH1,ASH1L,ATP7B,BAZ1A,BAZ2A,BIRC3,BIRC7,BPTF,BRCA1,CA1,CA12,CALB1,CECR1,CHD3,CHFR,CHORDC1,CIZ1,CLIP1,CNDP2,COX17,CPA2,CPA5,CPA6,CUL9,CXXC4,CYLD,CYP19A1,CYP2A6,CYP2B6,CYP2F1,CYP3A5,CYP3A7-CYP3A51P,CYP4A22,CYP4F12,CYP4F8,CYP4Z1,DBF4,DCTD,DNAJC21,DNAJC24,DPF1,DPP3,DPYS,DTNA,DTX1,DYRK2,EEA1,EHMT1,EHMT2,ENPP2,ERAP2,ERI2,ESR1,ESRRB,ESRRG,FAXDC2,FBLIM1,FBXO11,FHL1,FUS,G2E3,GALNT2,GATAD2A,GATAD2B,GDA,GPC1,GTF2B,GTF2H2,HDAC6,HLTF,INTS12,JADE1,JMJD6,KAT6A,KAT7,KDM1B,KDM5D,KDM7A,KMT2A,KMT2D,KMT2E,L3MBTL1,LCN2,LHX6,LHX9,LIG3,LIMCH1,LIMD1,LIMD2,LIMK1,LIMS2,LIMS3,LMO2,LMO3,LNPEP,LNX1,LONRF1,LOXL4,LPP,LTA4H,LTF,LTN1,MAN2A1,MAN2C1,MARCH5,MARCH6,MBTD1,MDM2,MDM4,MGRN1,MKRN1,MKRN3,MME,MMP19,MMP28,MNAT1,MOXD1,MPPE1,MSMO1,MTA1,MTA3,MT-CO1,MT-CO2,MTF2,MYNN,NAPEPLD,NFU1,NOS3,NPLOC4,NR2C1,NR3C1,NR3C2,NRDC,NSMCE1,NSMCE2,OGFOD1,P4HA1,PCGF3,PDLIM2,PDLIM3,PDLIM7,PDXK,PGLYRP2,PHC3,PHF1,PHF11,PHF12,PHF14,PHF20,PHF21A,PHF21B,PHF6,PIAS1,PLOD3,PMPCB,POLR2I,POLR2K,PPM1B,PPM1M,PRICKLE1,PTGR2,PXN,RABGGTB,RAD18,RANBP2,RAPSN,RBBP6,RBCK1,RBM4,RCHY1,RFWD3,RGN,RLF,RNF121,RNF13,RNF138,RNF14,RNF150,RNF166,RNF183,RNF2,RNF208,RNF212,RNF219,RNF220,RNF25,RNF32,RNF4,RNF43,RNF44,RNF6,RNF8,RNFT1,RORC,RXRA,SC5D,SCAF11,SCD5,SEC23B,SEC24A,SEC24B,SEC24D,SF1,SIRT2,SIRT5,SIRT6,SLC11A2,SLC30A5,SNAI3,SOD3,SPG7,SREK1IP1,SRSF7,ST18,SUPT4H1,TAB2,TAB3,TAF15,TAF2,TCEA2,TCF20,TF,TGFB1I1,TK1,TNKS,TRAF4,TRIM17,TRIM2,TRIM29,TRIM38,TRIM41,TRIM43,TRIM5,TRIM69,TRIM73,TRIP6,TTC3,TYW5,UBR4,UQCRC2,USP3,USP33,USP39,VPS11,VPS8,WHSC1,WHSC1L1,WRN,XIAP,XPNPEP3,ZCCHC11,ZCCHC13,ZCCHC17,ZCCHC8,ZDHHC16,ZDHHC17,ZDHHC4,ZDHHC8,ZEB1,ZFR,ZGRF1,ZMAT4,ZMYM1,ZMYM2,ZMYM5,ZNF195,ZNF2,ZNF207,ZNF208,ZNF253,ZNF257,ZNF276,ZNF330,ZNF385A,ZNF638,ZNF84,ZNF91,ZNF92,ZNRF2,ZRANB2,ZRANB3,ZSWIM8,ZYX,ZZZ3 270.1 0.00232 0.0769466666666667 GO:0070063 RNA polymerase binding molecular_function 40 16 AGO1,AGO2,BRD4,C14orf166,CCNT1,CCNT2,CTR9,ELP2,ELP4,PABPN1,RECQL5,SMYD2,SMYD3,UVSSA,WAC,ZNF326 7.86 0.00241 0.0788367123287671 GO:0019904 protein domain specific binding molecular_function 583 142 ADAM10,AIP,ARHGAP5,ARHGAP6,ARHGEF16,ARL1,ATF4,ATP2B1,ATP2B4,ATRX,BAX,BCAR1,BCL2,BOK,CABYR,CALM1,CASP8,CCDC6,CCDC88C,CENPJ,CLCN3,CTBP1,CTR9,CTTNBP2,CUL3,CXADR,CXXC4,DAB2IP,DAG1,DAPK3,DAPL1,DDX20,DDX6,DICER1,DLG3,DNAJA1,DOCK4,DTNA,DTX1,EHD2,EHMT1,EHMT2,EPHA4,ERC1,ESRRG,ETV6,EVL,EXOC4,FADD,FAF1,FAM189B,FMN1,FUT8,GSN,HEYL,HGS,HMGA2,HNRNPM,HOMER3,HOXB1,HOXC4,HSPA8,ICA1,IL1B,INPP5A,KCNN2,KHDRBS3,KRAS,L3MBTL1,LAMP2,LBR,LITAF,LLGL2,LNX1,LRRFIP2,LUC7L,MAFK,MEF2C,MITD1,MLF1,MTOR,MYH9,NCK1,NCKIPSD,NDE1,NFE2L2,NIPBL,NKD1,OPRM1,PAK3,PAWR,PAX3,PDE2A,PDZK1,PIAS1,PICK1,PLSCR4,PLXND1,POU2F2,PPP1CC,PRKCZ,PRRX1,PTEN,PTK2,PTPN6,RAB27B,RAPGEF2,REPS1,RNF2,ROBO1,RPS6KB1,SCAF1,SCNN1B,SENP2,SGIP1,SHANK2,SLC34A1,SNTG2,SON,SOS1,SP1,SRRM2,SRSF5,SSX2IP,STAMBP,STRN,TCF12,TLN1,TNK2,TNNI3,TOM1L1,TP63,TRADD,TRAF4,USP8,UVRAG,VPS11,VPS4A,WIZ,XPO1,YWHAQ,YWHAZ 114.6 0.00262 0.0823231578947368 GO:0003730 mRNA 3-UTR binding molecular_function 51 19 ANGEL2,BOLL,CPEB1,CPEB3,FXR1,HNRNPA2B1,HNRNPC,HNRNPD,IGF2BP3,PABPC1,PARN,PCBP4,PUM2,RBM4,RNPS1,SERBP1,YBX3,ZC3H12A,ZNF385A 10.03 0.00262 0.0823231578947368 GO:0004407 histone deacetylase activity molecular_function 51 19 ARID4A,CHD3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MTA1,MTA3,PHF21A,RBBP4,RBBP7,SAP18,SIRT2,SIRT6,VEGFA 10.03 0.00262 0.0823231578947368 GO:0016810 hydrolase activity, acting on carbon-nit... molecular_function 154 45 ADA,ADAD2,ADAT2,AMDHD2,AMPD3,APOBEC3B,APOBEC3F,ARID4A,ASAH1,ASPG,ATIC,CECR1,CHD3,CPS1,DARS,DCTD,DPYS,GDA,GLS,GLS2,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MTA1,MTA3,MTHFD1,MTHFD2L,NADSYN1,NIT2,NTAN1,PGLYRP2,PHF21A,RBBP4,RBBP7,SAP18,SIRT2,SIRT5,SIRT6,VEGFA,WDYHV1 30.27 0.00274 0.0849755844155844 GO:0046966 thyroid hormone receptor binding molecular_function 27 12 FUS,GTF2B,JMJD1C,MED13,MED16,MED24,MED30,NCOA6,NCOR1,THRAP3,TRIP12,TRIP6 5.31 0.00295 0.0903153846153846 GO:0003725 double-stranded RNA binding molecular_function 63 22 ACTN1,AGO1,AGO2,CLTC,DDX1,DHX15,DICER1,DROSHA,EIF2AK2,EIF4A1,EIF4B,EIF4H,FXR1,HSPD1,MBNL1,MTDH,SIDT2,STAU2,TARBP2,TFRC,TLR7,YRDC 12.38 0.00323 0.0976359493670886 GO:0033558 protein deacetylase activity molecular_function 52 19 ARID4A,CHD3,HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,MAPK8,MBD3,MTA1,MTA3,PHF21A,RBBP4,RBBP7,SAP18,SIRT2,SIRT6,VEGFA 10.22 0.00338 0.100893 GO:0004298 threonine-type endopeptidase activity molecular_function 21 10 PRSS50,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,TASP1 4.13 0.00355 0.103382926829268 GO:0070003 threonine-type peptidase activity molecular_function 21 10 PRSS50,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMB4,PSMB9,TASP1 4.13 0.00355 0.103382926829268 GO:0016776 phosphotransferase activity, phosphate g... molecular_function 42 16 AK2,AK6,CASK,CMPK1,DLG2,DLG3,DTYMK,GUK1,IP6K2,NME4,NME5,NME6,NME7,NME9,PPIP5K1,PPIP5K2 8.26 0.00430 0.123715662650602 GO:0005085 guanyl-nucleotide exchange factor activi... molecular_function 306 79 ABR,AMPH,ARHGAP4,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CALM1,CAMK2A,CAMK2G,CCZ1,CYTH4,DENND1B,DENND1C,DENND4A,DENND4C,DOCK4,DOCK7,ECT2,EGF,EGFR,EPHA4,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GFRA2,IL2RA,ITSN2,KALRN,LAMTOR1,LAMTOR3,LAT,MADD,MCF2,MCF2L,NCK1,P2RY12,PDGFRB,PLEKHG2,PLEKHG6,PREB,PSD3,PSD4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RAP1A,RAPGEF2,RAPGEF4,RASGEF1A,RASGRP2,RASGRP4,RGL4,RIC1,RIC8B,RPGR,SBF1,SH2D3C,SHC2,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TRIO,TRIP10,VAV1 60.15 0.00479 0.136172857142857 GO:0019205 nucleobase-containing compound kinase ac... molecular_function 50 18 ADK,AK2,AK6,CASK,CMPK1,DLG2,DLG3,DTYMK,GUK1,NME4,NME5,NME6,NME7,NME9,NT5C2,PNKP,TK1,UPRT 9.83 0.00512 0.143841882352941 GO:0008641 small protein activating enzyme activity molecular_function 10 6 NAE1,SAE1,UBA2,UBA3,UBA5,UBA6 1.97 0.00581 0.159474482758621 GO:0017166 vinculin binding molecular_function 10 6 ACTN1,CTNNA1,DAG1,PXN,SORBS3,TLN1 1.97 0.00581 0.159474482758621 GO:0043022 ribosome binding molecular_function 47 17 C12orf65,C1QBP,CPEB1,CPEB3,EIF2A,EIF6,IMPACT,LETM2,LETMD1,MTIF3,MTOR,MTRF1,MTRF1L,NAA10,NAA16,RPN2,ZC3H12A 9.24 0.00609 0.16326652173913 GO:0017136 NAD-dependent histone deacetylase activi... molecular_function 16 8 HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,SIRT2,SIRT6 3.15 0.00625 0.16326652173913 GO:0035198 miRNA binding molecular_function 16 8 AGO1,AGO2,HNRNPA2B1,MEF2C,PNPT1,RBM4,TARBP2,ZC3H12A 3.15 0.00625 0.16326652173913 GO:0016433 rRNA (adenine) methyltransferase activit... molecular_function 5 4 DIMT1,METTL16,RRNAD1,TFB1M 0.98 0.00628 0.16326652173913 GO:0019003 GDP binding molecular_function 372 93 ABR,AMPH,ARF1,ARHGAP4,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CALM1,CAMK2A,CAMK2G,CCZ1,CYTH4,DENND1B,DENND1C,DENND4A,DENND4C,DOCK4,DOCK7,DYNC1LI1,ECT2,EGF,EGFR,EPHA4,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GCGR,GDI2,GFRA2,GPSM1,IL2RA,ITGB1BP1,ITSN2,KALRN,KRAS,LAMTOR1,LAMTOR3,LAT,MADD,MCF2,MCF2L,NCK1,P2RY12,PDGFRB,PLEKHG2,PLEKHG6,PREB,PSD3,PSD4,PTK2,PTPRA,RAB18,RAB22A,RAB27B,RAB2A,RAB3GAP2,RAB3IP,RAB5A,RALB,RAP1A,RAP1B,RAPGEF2,RAPGEF4,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGS14,RIC1,RIC8B,RPGR,SBF1,SH2D3C,SHC2,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TRIO,TRIP10,VAV1 73.13 0.00629 0.16326652173913 GO:0030234 enzyme regulator activity molecular_function 1216 273 ABCE1,ABI1,ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,AHSA2,AKT1,AMPH,ANGPTL3,ANKLE2,ANXA2,ANXA4,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARPP19,ATP1B1,AZIN2,BAG4,BCAS3,BCCIP,BIRC3,BIRC6,BIRC7,BMP2K,BNIP2,C4A,C4B,CABIN1,CALM1,CAMK2A,CAMK2G,CARD16,CCNC,CCNE2,CCNL2,CCNT1,CCNT2,CCZ1,CDC20B,CDC42EP3,CFLAR,CHAD,CHN1,COL4A3,CSTL1,CTC1,CYTH4,DAB2IP,DBF4,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DMPK,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,ECT2,EGF,EGFR,EIF2AK2,ELMOD3,ELP4,EPHA4,EPS8L1,ESR1,FAF1,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FGFR1OP,FNBP1,FNBP1L,FRS2,FRY,FZR1,GCGR,GCLM,GDI2,GFRA2,GMFB,GMFG,GMIP,GPC3,GPRC5B,GPSM1,GRM7,GSTP1,H2AFY,HACD3,HSPH1,HTR2B,IL2RA,INPP5B,ITGB1BP1,ITSN2,KALRN,KAT2B,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,LRP6,LRRTM1,LRRTM3,LTF,MADD,MALT1,MAPK8,MCF2,MCF2L,MTMR9,NCK1,NF1,NLRP12,NPRL3,NSMAF,OAZ1,OAZ2,OCRL,OGT,OVOS2,P2RY12,PAK2,PCOLCE2,PDCD5,PDE6D,PDGFRB,PDZD3,PFN2,PIK3CA,PIK3R2,PIK3R3,PIK3R5,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PODN,POT1,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4R1,PREB,PRKAR2A,PRLR,PSD3,PSD4,PSMD1,PSMD2,PSME3,PSME4,PTK2,PTPRA,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RAC2,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RIMS1,RNH1,RP2,RPGR,RPS6KA1,RTN4RL2,RUNDC1,SAE1,SBF1,SEPT2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SFTPB,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SOS1,SPATA13,SPINT2,SPOCK3,SPTB,SPTBN1,SPTBN4,ST5,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TEFM,TFPI,TGFB1,THY1,TMBIM6,TNK2,TOM1L1,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,UBA2,UCHL5,UGT1A1,USP6NL,VAV1,VIL1,WFDC2,WNT11,XIAP 239.04 0.00654 0.166905957446809 GO:0005096 GTPase activator activity molecular_function 274 71 ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,BNIP2,CDC42EP3,CHN1,DAB2IP,DEPDC1,DNM1L,DOCK4,ECT2,ELMOD3,FAM13B,GDI2,GMIP,HACD3,HTR2B,INPP5B,KALRN,LLGL2,NF1,NPRL3,OCRL,PIK3R2,PLCB1,PLEKHG6,PLXNB1,RAB3GAP2,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1GAP2,RAP1GDS1,RAPGEF2,RASA2,RASA3,RASAL3,RGS14,RGS3,RGS6,RIC8B,RP2,RUNDC1,SGSM1,SGSM3,SIPA1,SOS1,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TRIP10,USP6NL,WNT11 53.86 0.00657 0.166905957446809 GO:0019239 deaminase activity molecular_function 33 13 ADA,ADAD2,ADAT2,AMPD3,APOBEC3B,APOBEC3F,CECR1,DCTD,FTCD,GDA,GNPDA2,RPUSD1,RPUSD4 6.49 0.00700 0.169391775700935 GO:0098772 molecular function regulator molecular_function 1358 302 ABCE1,ABI1,ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,AHSA2,AKT1,AMPH,ANGPTL3,ANKLE2,ANXA2,ANXA4,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARPP19,ATP1B1,ATP2B4,AZIN2,BAG4,BCAS3,BCCIP,BCL2,BIRC3,BIRC6,BIRC7,BMP2K,BNIP2,C4A,C4B,CABIN1,CACNA2D4,CALM1,CAMK2A,CAMK2G,CARD16,CCNC,CCNE2,CCNL2,CCNT1,CCNT2,CCZ1,CDC20B,CDC42EP3,CFLAR,CHAD,CHN1,CHRNA7,COL4A3,CSTL1,CTC1,CYTH4,DAB2IP,DBF4,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DMPK,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,DOCK7,DPP10,ECT2,EGF,EGFR,EIF2AK2,ELMOD3,ELP4,EPHA4,EPS8L1,ESR1,FAF1,FAM13B,FAM150A,FAM58A,FARP1,FARP2,FGD3,FGD4,FGD6,FGF12,FGF5,FGFR1,FGFR1OP,FNBP1,FNBP1L,FNTA,FRS2,FRY,FXYD1,FZR1,GCGR,GCLM,GDI2,GFRA2,GMFB,GMFG,GMIP,GPC3,GPRC5B,GPSM1,GRM7,GSTP1,H2AFY,HACD3,HSPH1,HTR2B,IL18BP,IL2RA,INPP5B,ITGB1BP1,ITPR1,ITSN2,KALRN,KAT2B,KCNAB2,KCNIP4,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,LRP6,LRRTM1,LRRTM3,LTF,LYNX1,MADD,MALT1,MAPK8,MCF2,MCF2L,MED16,MTMR9,NCK1,NCOA2,NEDD4L,NF1,NLRP12,NPRL3,NRXN1,NSMAF,OAZ1,OAZ2,OCRL,OGT,OVOS2,P2RY12,PAK2,PCOLCE2,PDCD5,PDE6D,PDGFRB,PDZD3,PFN2,PIK3CA,PIK3R2,PIK3R3,PIK3R5,PKP2,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PODN,POT1,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4R1,PREB,PRKAR2A,PRKCZ,PRLR,PSD3,PSD4,PSMD1,PSMD2,PSME3,PSME4,PTK2,PTPRA,PXDN,RAB3GAP2,RAB3IP,RABEP1,RABGAP1L,RAC2,RACGAP1,RALGAPB,RAP1A,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RIC1,RIC8B,RIMS1,RNH1,RP2,RPGR,RPS6KA1,RTN4RL2,RUNDC1,SAE1,SBF1,SCN3B,SEPT2,SERPINA12,SERPINA3,SERPINB10,SERPINB11,SERPINB4,SERPINE3,SFTPB,SGK1,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SOS1,SPATA13,SPINT2,SPOCK3,SPTB,SPTBN1,SPTBN4,SRI,ST5,STIM2,STX8,SUMO1,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TEFM,TFPI,TGFB1,THY1,TMBIM6,TNK2,TNNI3,TOM1L1,TOR1AIP1,TOR1AIP2,TRIO,TRIP10,UBA2,UCHL5,UGT1A1,USP6NL,VAV1,VEGFA,VIL1,WFDC2,WNT10B,WNT11,XIAP 266.95 0.00736 0.169391775700935 GO:0004359 glutaminase activity molecular_function 3 3 GLS,GLS2,NADSYN1 0.59 0.00759 0.169391775700935 GO:0004814 arginine-tRNA ligase activity molecular_function 3 3 DALRD3,RARS,RARS2 0.59 0.00759 0.169391775700935 GO:0008428 ribonuclease inhibitor activity molecular_function 3 3 ABCE1,RNH1,TMBIM6 0.59 0.00759 0.169391775700935 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-... molecular_function 3 3 MGAT4A,MGAT4B,MGAT4C 0.59 0.00759 0.169391775700935 GO:0015091 ferric iron transmembrane transporter ac... molecular_function 3 3 SLC11A2,TF,TFRC 0.59 0.00759 0.169391775700935 GO:0017099 very-long-chain-acyl-CoA dehydrogenase a... molecular_function 3 3 ACAD11,ACADVL,TECR 0.59 0.00759 0.169391775700935 GO:0046976 histone methyltransferase activity (H3-K... molecular_function 3 3 EHMT1,EHMT2,EZH2 0.59 0.00759 0.169391775700935 GO:0051032 nucleic acid transmembrane transporter a... molecular_function 3 3 HNRNPA3,SIDT1,SIDT2 0.59 0.00759 0.169391775700935 GO:0051033 RNA transmembrane transporter activity molecular_function 3 3 HNRNPA3,SIDT1,SIDT2 0.59 0.00759 0.169391775700935 GO:0055100 adiponectin binding molecular_function 3 3 ADIPOR1,ADIPOR2,CDH13 0.59 0.00759 0.169391775700935 GO:0072510 trivalent inorganic cation transmembrane... molecular_function 3 3 SLC11A2,TF,TFRC 0.59 0.00759 0.169391775700935 GO:0016407 acetyltransferase activity molecular_function 108 32 ACAT1,ATAT1,ATF2,BAZ1A,BCAS3,DLAT,ELP4,GCAT,GNPAT,HAT1,HGSNAT,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,LPCAT4,MED24,NAA10,NAA16,NAA20,NAA25,NAA60,NAT1,NAT10,NCOA1,NCOA2,OGT,PDCD5,PHF20,SMARCE1 21.23 0.00834 0.184406666666667 GO:0016763 transferase activity, transferring pento... molecular_function 56 19 APRT,ART3,HMGN1,HPRT1,PARP10,PARP12,PARP14,PARP2,PARP6,PARP8,PDCL3,POGLUT1,QTRT1,SIRT2,SIRT5,SIRT6,TGFB1,TIPARP,TNKS 11.01 0.00846 0.184527272727273 GO:0008017 microtubule binding molecular_function 215 57 ARHGEF2,CAMSAP3,CCDC88A,CEP290,CEP350,CEP57,CEP57L1,CLASP1,CLASP2,CLIP1,CLIP2,CRYAB,DCTN1,DNM1L,DNM3,EML2,EML4,FAM175B,FES,FMN1,FNTA,FTCD,GLI1,HDAC6,HOOK1,KIF13A,KIF15,KIF1A,KIF21B,KIF23,KIF6,KIFC2,KIFC3,KRIT1,LRPPRC,MAP1LC3B,MAP1S,MAP2,MAP6,MAP6D1,MDM1,NDE1,NUSAP1,OPA1,PAFAH1B1,POLB,PRC1,RACGAP1,RAE1,REEP1,RGS14,SGIP1,SPAG8,TPGS1,TUBGCP5,WDR43,ZNF207 42.26 0.00850 0.184527272727273 GO:0008601 protein phosphatase type 2A regulator ac... molecular_function 20 9 ANKLE2,ARPP19,EIF2AK2,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E 3.93 0.00885 0.188694642857143 GO:0017025 TBP-class protein binding molecular_function 20 9 CAND1,DR1,GTF2B,PSMC1,PSMC2,PSMC4,PSMC5,PSMC6,TAF1B 3.93 0.00885 0.188694642857143 GO:0005089 Rho guanyl-nucleotide exchange factor ac... molecular_function 80 25 ABR,ARHGAP4,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ECT2,EPHA4,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,ITSN2,KALRN,MCF2,MCF2L,PLEKHG2,PLEKHG6,SOS1,SPATA13,TRIO,VAV1 15.73 0.00909 0.192096637168142 GO:0031492 nucleosomal DNA binding molecular_function 34 13 ACTL6A,CENPA,GATAD2B,H2AFY,HDAC1,HDAC2,HMGA2,HMGN1,HNRNPC,MBD3,RBBP4,SMARCD2,SMARCE1 6.68 0.00932 0.195229473684211 GO:0001135 transcription factor activity, RNA polym... molecular_function 8 5 DMTF1,LIF,MYB,SNAPC4,TTF1 1.57 0.00963 0.196550769230769 GO:0016742 hydroxymethyl-, formyl- and related tran... molecular_function 8 5 ALDH1L1,ATIC,FTCD,GART,SHMT2 1.57 0.00963 0.196550769230769 GO:0035197 siRNA binding molecular_function 8 5 AGO2,DICER1,TARBP2,TLR7,TLR9 1.57 0.00963 0.196550769230769 GO:0034979 NAD-dependent protein deacetylase activi... molecular_function 17 8 HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9,SIRT2,SIRT6 3.34 0.00980 0.196658823529412 GO:0070577 lysine-acetylated histone binding molecular_function 17 8 BAZ2A,BRD2,BRD3,BRD4,BRD7,KMT2A,PHIP,PSME4 3.34 0.00980 0.196658823529412 GO:0047485 protein N-terminus binding molecular_function 97 29 CALM1,CHMP6,CSNK2A1,CSNK2A2,DCTN4,EXOC4,FEZ1,GTF2H2,GTF2H3,HDAC1,HESX1,MAU2,MNAT1,MORF4L1,NCOA1,NCOR2,NIPBL,PDCD10,PPP1CC,RBPJ,SCFD1,SDCBP,SMARCE1,SRRM2,STX5,TARBP2,TBL1XR1,TGFB1,YWHAQ 19.07 0.01022 0.203378 GO:0001134 transcription factor activity, transcrip... molecular_function 11 6 DMTF1,LIF,MYB,SNAPC4,TAF1B,TTF1 2.16 0.01066 0.208852131147541 GO:0051020 GTPase binding molecular_function 302 76 ACAP2,ADPRHL1,ANXA2,AP1G1,ARHGAP4,ARHGEF16,ARHGEF2,BICD1,BICDL2,BRAF,CDC42EP3,CSE1L,CYFIP1,DAAM1,DAPK3,DENND1B,DMXL2,DNM1L,DOCK4,DOCK7,ECT2,EPRS,ERC1,EXOC1,EXOC4,EXPH5,FGD3,FGD4,FGD6,FMNL2,GDI2,GOLGA4,HACE1,IPO11,IPO8,IPO9,LCP1,LLGL2,MARCH5,MLPH,NOX1,NUP50,OCRL,PAK3,PDE6D,PEX5L,PTPRN,RAB11FIP2,RAB3GAP2,RABGAP1L,RABGGTB,RANBP2,RAP1A,RAPGEF4,RIC1,RIMS1,RUNDC1,SGSM1,SGSM3,SH3GL1,SORL1,SPTBN1,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TNPO1,TRIOBP,USP33,USP6NL,XPO1,XPO7,XPOT,YBX3 59.37 0.01067 0.208852131147541 GO:0003924 GTPase activity molecular_function 890 202 ABR,ACAP1,ACAP2,ADCYAP1,ADPRHL1,AGFG1,AMPH,ARAP2,ARF1,ARFGAP2,ARFRP1,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,ARL1,ARL2BP,ARL8A,ATL2,BCAS3,BMS1,BNIP2,CALM1,CAMK2A,CAMK2G,CCL25,CCZ1,CDC42,CDC42EP3,CHN1,CYTH4,DAB2IP,DENND1B,DENND1C,DENND4A,DENND4C,DEPDC1,DNM1L,DNM3,DOCK4,DOCK7,ECT2,EGF,EGFR,EIF2S3,EIF5B,ELMOD3,EPHA4,EPS8L1,EZH2,FAM13B,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FNBP1,FNBP1L,FRS2,GBP5,GCGR,GDI2,GFRA2,GMIP,GNA12,GNA14,GNGT1,GNL2,GPSM1,GSK3B,GTPBP10,HACD3,HTR2B,IL2RA,INPP5B,ITGA6,ITGB1BP1,ITSN2,KALRN,KRAS,KRIT1,LAMTOR1,LAMTOR3,LAT,LLGL2,MADD,MCF2,MCF2L,MFN1,MMAA,MSTO1,MTG1,MTIF2,MTOR,NCK1,NF1,NPRL3,NTRK2,OCRL,OPA1,P2RY12,PAFAH1B1,PDE6D,PDGFRB,PIK3R2,PIN1,PKP4,PLCB1,PLEKHG2,PLEKHG6,PLXNB1,PREB,PSD3,PSD4,PTK2,PTPRA,RAB18,RAB1A,RAB22A,RAB27B,RAB2A,RAB30,RAB3GAP2,RAB3IP,RAB5A,RABEP1,RABGAP1L,RABL2A,RAC2,RACGAP1,RALB,RALGAPB,RAP1A,RAP1B,RAP1GAP2,RAP1GDS1,RAPGEF2,RAPGEF4,RASA2,RASA3,RASAL3,RASGEF1A,RASGRP2,RASGRP4,RGL4,RGN,RGS14,RGS3,RGS6,RHOF,RHOT1,RIC1,RIC8B,RIMS1,RIT1,RP2,RPGR,RRAGB,RRAS2,RUNDC1,SBF1,SEMA4D,SEPT4,SEPT5,SEPT9,SGSM1,SGSM3,SH2D3C,SHC2,SIPA1,SNX9,SOS1,SPATA13,SPRY1,SPTB,SPTBN1,SPTBN4,ST5,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,THY1,TMED2,TNK2,TRIO,TRIP10,TUBB8,USP6NL,VAV1,WNT11 174.95 0.01149 0.22179744 GO:0016779 nucleotidyltransferase activity molecular_function 170 46 AURKB,CDS2,CHRAC1,COASY,CRCP,CTC1,EIF4A2,FLAD1,GRHL2,MAP2K7,MAPKAPK5,MED21,NEK7,NMNAT3,NVL,PAPD4,PAPOLG,PCYT1A,PNKP,PNPT1,POLA1,POLA2,POLB,POLD3,POLD4,POLI,POLK,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,POT1,PRIM1,REV1,RFC2,RFC4,TCP1,TNKS,UGP2,YRDC,ZCCHC11 33.42 0.01156 0.22179744 GO:0005543 phospholipid binding molecular_function 362 89 AKT1,ALOX15,AMER1,AMER3,AMPH,ANXA2,ANXA4,ANXA6,ANXA7,ARAP2,ARHGAP26,ARHGAP33,ARL6,BIN2,BTK,C2CD5,CARMIL2,CCDC88A,CEACAM5,CHMP3,CPNE1,CPNE3,CPS1,DAB2IP,DGKA,DYSF,EEA1,EXOC1,FCHO2,FES,FRMPD2,GRB7,HSPA8,ITPR1,KRIT1,LANCL2,LDLRAP1,MARK1,MCF2L,MCTP1,MFGE8,MITD1,MPPE1,MYO10,MYO1B,MYO1G,NF1,NISCH,NSMAF,NUP35,OGT,OSBPL10,OSBPL1A,OSBPL5,OSBPL8,PCYT1A,PFN2,PHF12,PLA2G4B,PLA2G4C,PLCB1,PLD1,PLEKHA4,PON1,PSD4,RACGAP1,RAPGEF2,RPS6KC1,SGIP1,SH3YL1,SNAP91,SNX14,SNX16,SNX19,SNX2,SNX31,SNX4,SNX9,SPTBN1,SPTBN4,SYT1,SYT5,SYTL2,THY1,TWF1,VIL1,VPS36,WDR45B,ZFYVE16 71.16 0.01161 0.22179744 GO:0019783 ubiquitin-like protein-specific protease... molecular_function 94 28 ATXN3,BAP1,CYLD,EIF3F,FAM76B,MYSM1,OTUD4,OTULIN,SENP2,SENP6,STAMBP,TANK,UCHL5,USP12,USP15,USP25,USP3,USP32,USP33,USP34,USP36,USP4,USP7,USP8,USP9X,USPL1,VCPIP1,ZC3H12A 18.48 0.01208 0.228944761904762 GO:0008170 N-methyltransferase activity molecular_function 86 26 ASH1L,DIMT1,DOT1L,EHMT1,EHMT2,EZH2,FBXO11,KMT2A,KMT2D,KMT2E,METTL15,METTL16,METTL21A,NDUFAF7,PNMT,PRDM16,PRMT1,PRMT3,PRMT5,RRNAD1,SMYD2,SMYD3,TFB1M,TRMT1L,WHSC1,WHSC1L1 16.91 0.01248 0.234663307086614 GO:0002039 p53 binding molecular_function 66 21 BANP,BRD4,BRD7,EHMT1,EHMT2,GSK3B,HSPD1,MAPKAPK5,MDM2,NTRK3,PLK3,PSME3,PTTG1IP,RCHY1,RFWD3,SMYD2,TP63,TRIM29,USP7,ZMAT4,ZNF385A 12.97 0.01290 0.240665625 GO:0051059 NF-kappaB binding molecular_function 28 11 ANXA4,CDK5RAP3,CPNE1,FAF1,GSK3B,HDAC1,HDAC2,MTDH,NFKBID,PSMA6,RNF25 5.5 0.01302 0.241021395348837 GO:0031491 nucleosome binding molecular_function 51 17 ACTL6A,CABIN1,CENPA,GATAD2B,H2AFY,HDAC1,HDAC2,HMGA2,HMGN1,HNRNPC,L3MBTL1,MBD3,RBBP4,RNF4,SMARCA5,SMARCD2,SMARCE1 10.03 0.01489 0.273517846153846 GO:0004708 MAP kinase kinase activity molecular_function 71 22 ADORA1,BRAF,DAB2IP,EGF,EGFR,EIF2AK2,FRS2,GADD45G,IGF1R,LAMTOR3,MAP2K3,MAP2K4,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPKAPK5,PAK3,RAP1A,TGFBR1 13.96 0.01532 0.279268396946565 GO:0008047 enzyme activator activity molecular_function 477 113 ABI1,ABR,ACAP1,ACAP2,ADPRHL1,AGFG1,AHSA2,ARAP2,ARFGAP2,ARHGAP26,ARHGAP33,ARHGAP4,ARHGAP5,ARHGAP6,ARHGAP8,ARHGEF1,ARHGEF12,ARHGEF15,ARL1,ATP1B1,AZIN2,BCAS3,BNIP2,CALM1,CDC42EP3,CFLAR,CHN1,DAB2IP,DBF4,DEPDC1,DNAJC1,DNAJC10,DNAJC24,DNM1L,DOCK4,ECT2,EGF,ELMOD3,FAM13B,FAM150A,FAM58A,FRS2,GDI2,GMFB,GMFG,GMIP,GPRC5B,HACD3,HTR2B,INPP5B,KALRN,LAMTOR3,LLGL2,LTF,MADD,MALT1,NF1,NLRP12,NPRL3,NSMAF,OCRL,OGT,PAK2,PCOLCE2,PDCD5,PIK3CA,PIK3R2,PLCB1,PLEKHG6,PLXNB1,PPP1R12B,PRLR,PSME3,PSME4,RAB3GAP2,RABEP1,RABGAP1L,RACGAP1,RALGAPB,RAP1GAP2,RAP1GDS1,RAPGEF2,RASA2,RASA3,RASAL3,RGS14,RGS3,RGS6,RIC8B,RP2,RUNDC1,SAE1,SFTPB,SGSM1,SGSM3,SIPA1,SOS1,TANK,TBC1D10C,TBC1D15,TBC1D19,TBC1D2B,TBC1D5,TBCK,TGFB1,THY1,TOM1L1,TOR1AIP1,TOR1AIP2,TRIP10,UBA2,USP6NL,WNT11 93.77 0.01565 0.283122727272727 GO:0030235 nitric-oxide synthase regulator activity molecular_function 6 4 AKT1,CALM1,EGFR,ESR1 1.18 0.01591 0.283530447761194 GO:0042979 ornithine decarboxylase regulator activi... molecular_function 6 4 AZIN2,OAZ1,OAZ2,PRLR 1.18 0.01591 0.283530447761194 GO:0005521 lamin binding molecular_function 15 7 LBR,NARF,PLCB1,PPP1CC,SYNE1,TMPO,TOR1AIP1 2.95 0.01641 0.283964347826087 GO:0008266 poly(U) RNA binding molecular_function 15 7 HNRNPC,HNRNPH1,MSI1,MSI2,PABPC1,PNPT1,RBM11 2.95 0.01641 0.283964347826087 GO:0008649 rRNA methyltransferase activity molecular_function 15 7 DIMT1,FBL,METTL15,METTL16,NOP2,RRNAD1,TFB1M 2.95 0.01641 0.283964347826087 GO:0042809 vitamin D receptor binding molecular_function 15 7 MED13,MED14,MED16,MED24,MED30,RXRA,THRAP3 2.95 0.01641 0.283964347826087 GO:0008757 S-adenosylmethionine-dependent methyltra... molecular_function 143 39 ASH1L,CMTR2,DIMT1,DOT1L,DPH5,EHMT1,EHMT2,EZH2,FBL,FBXO11,KMT2A,KMT2D,KMT2E,LCMT1,METTL1,METTL14,METTL15,METTL16,METTL21A,NDUFAF7,NOP2,PCMT1,PCMTD1,PNMT,PRDM16,PRMT1,PRMT3,PRMT5,RRNAD1,RRP8,SMYD2,SMYD3,TARBP1,TFB1M,THUMPD3,TRMT10C,TRMT1L,WHSC1,WHSC1L1 28.11 0.01663 0.285701007194245 GO:0031078 histone deacetylase activity (H3-K14 spe... molecular_function 12 6 HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9 2.36 0.01782 0.301802553191489 GO:0032041 NAD-dependent histone deacetylase activi... molecular_function 12 6 HDAC1,HDAC2,HDAC6,HDAC7,HDAC8,HDAC9 2.36 0.01782 0.301802553191489 GO:0005088 Ras guanyl-nucleotide exchange factor ac... molecular_function 228 58 ABR,ARHGAP4,ARHGEF1,ARHGEF12,ARHGEF15,ARHGEF16,ARHGEF2,CALM1,CAMK2A,CAMK2G,DENND1B,DENND1C,DENND4A,DENND4C,ECT2,EGF,EGFR,EPHA4,EPS8L1,FARP1,FARP2,FGD3,FGD4,FGD6,FGF5,FGFR1,FRS2,GFRA2,IL2RA,ITSN2,KALRN,LAT,MADD,MCF2,MCF2L,PDGFRB,PLEKHG2,PLEKHG6,PTK2,PTPRA,RAB3GAP2,RAB3IP,RAP1A,RAPGEF2,RAPGEF4,RASGEF1A,RASGRP4,RIC1,SBF1,SHC2,SOS1,SPATA13,SPTB,SPTBN1,SPTBN4,ST5,TRIO,VAV1 44.82 0.01886 0.31716676056338 GO:0051721 protein phosphatase 2A binding molecular_function 26 10 AKT1,ANKLE2,ARPP19,BCL2,CTTNBP2NL,DAB2IP,MASTL,PPP2R2A,RPS6KB1,STRN 5.11 0.02062 0.343542620689655 GO:0015662 ATPase activity, coupled to transmembran... molecular_function 41 14 ATP1B1,ATP2A3,ATP2B1,ATP2B4,ATP2C1,ATP2C2,ATP6V0D1,ATP6V1C2,ATP7B,PCYOX1,RGN,RYR2,SUMO1,TLR9 8.06 0.02086 0.343542620689655 GO:0016831 carboxy-lyase activity molecular_function 41 14 ACOD1,AMD1,AZIN2,BCKDHB,DDT,ECHDC1,GGCX,HDC,OAZ1,OAZ2,PCK2,PPCDC,PRLR,SGPL1 8.06 0.02086 0.343542620689655 GO:0005546 phosphatidylinositol-4,5-bisphosphate bi... molecular_function 57 18 ALOX15,AMER1,AMER3,ANXA2,EXOC1,FCHO2,KRIT1,LDLRAP1,MARK1,MYO1B,MYO1G,PFN2,PLCB1,SYT1,SYT5,SYTL2,TWF1,VIL1 11.2 0.02202 0.360162739726027 GO:0031267 small GTPase binding molecular_function 280 69 ACAP2,ADPRHL1,ANXA2,AP1G1,ARHGAP4,ARHGEF16,ARHGEF2,BICD1,BICDL2,BRAF,CDC42EP3,CSE1L,CYFIP1,DAAM1,DAPK3,DENND1B,DMXL2,DNM1L,DOCK4,DOCK7,ECT2,ERC1,EXOC1,EXOC4,EXPH5,FGD3,FGD4,FGD6,FMNL2,GDI2,HACE1,IPO11,IPO8,IPO9,LLGL2,MLPH,NOX1,NUP50,OCRL,PAK3,PDE6D,PEX5L,RAB11FIP2,RAB3GAP2,RABGAP1L,RABGGTB,RANBP2,RAP1A,RAPGEF4,RIC1,RIMS1,RUNDC1,SGSM1,SGSM3,SORL1,SYTL2,TBC1D10C,TBC1D15,TBC1D2B,TBC1D5,TBCK,TNPO1,TRIOBP,USP33,USP6NL,XPO1,XPO7,XPOT,YBX3 55.04 0.02272 0.369084081632653 GO:1901981 phosphatidylinositol phosphate binding molecular_function 120 33 AKT1,ALOX15,AMER1,AMER3,ANXA2,ARAP2,BTK,DAB2IP,EXOC1,FCHO2,KRIT1,LANCL2,LDLRAP1,MARK1,MYO10,MYO1B,MYO1G,OGT,OSBPL5,OSBPL8,PFN2,PLCB1,RACGAP1,SNX14,SNX19,SYT1,SYT5,SYTL2,TWF1,VIL1,VPS36,WDR45B,ZFYVE16 23.59 0.02312 0.373044324324324 GO:0004843 ubiquitin-specific protease activity molecular_function 82 24 ATXN3,BAP1,CYLD,EIF3F,MYSM1,OTUD4,OTULIN,STAMBP,TANK,UCHL5,USP12,USP15,USP25,USP3,USP32,USP33,USP34,USP36,USP4,USP7,USP8,USP9X,VCPIP1,ZC3H12A 16.12 0.02363 0.3761896 GO:0036459 ubiquitinyl hydrolase activity molecular_function 82 24 ATXN3,BAP1,CYLD,EIF3F,MYSM1,OTUD4,OTULIN,STAMBP,TANK,UCHL5,USP12,USP15,USP25,USP3,USP32,USP33,USP34,USP36,USP4,USP7,USP8,USP9X,VCPIP1,ZC3H12A 16.12 0.02363 0.3761896 GO:0003727 single-stranded RNA binding molecular_function 70 21 AGO1,AGO2,DDX1,EIF4B,EIF4H,FXR1,HNRNPC,HNRNPH1,HNRNPU,JMJD6,MSI1,MSI2,PABPC1,PNPT1,POLR2G,RBM11,RBM7,RBPMS,TIA1,TLR7,TRA2B 13.76 0.02519 0.376983658536585 GO:0034212 peptide N-acetyltransferase activity molecular_function 70 21 ATAT1,ATF2,BAZ1A,ELP4,HAT1,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,MED24,NAA10,NAA16,NAA20,NAA25,NAA60,NCOA1,NCOA2,OGT,PHF20 13.76 0.02519 0.376983658536585 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferas... molecular_function 4 3 DIMT1,RRNAD1,TFB1M 0.79 0.02589 0.376983658536585 GO:0000340 RNA 7-methylguanosine cap binding molecular_function 4 3 AGO2,NCBP2,NCBP3 0.79 0.02589 0.376983658536585 GO:0001847 opsonin receptor activity molecular_function 4 3 C5AR2,CD14,CR1 0.79 0.02589 0.376983658536585 GO:0004466 long-chain-acyl-CoA dehydrogenase activi... molecular_function 4 3 ACAD11,ACADVL,TECR 0.79 0.02589 0.376983658536585 GO:0004594 pantothenate kinase activity molecular_function 4 3 PANK1,PANK3,PANK4 0.79 0.02589 0.376983658536585 GO:0016149 translation release factor activity, cod... molecular_function 4 3 C12orf65,MTRF1,MTRF1L 0.79 0.02589 0.376983658536585 GO:0032407 MutSalpha complex binding molecular_function 4 3 ATR,MUTYH,PMS2 0.79 0.02589 0.376983658536585 GO:0033592 RNA strand annealing activity molecular_function 4 3 EIF4B,EIF4H,FXR1 0.79 0.02589 0.376983658536585 GO:0038064 collagen receptor activity molecular_function 4 3 DDR1,DDR2,ITGA2 0.79 0.02589 0.376983658536585 GO:0042296 ISG15 transferase activity molecular_function 4 3 HERC5,UBE2E1,UBE2E2 0.79 0.02589 0.376983658536585 GO:0048408 epidermal growth factor binding molecular_function 4 3 EGFR,NRDC,SEC61B 0.79 0.02589 0.376983658536585 GO:0097371 MDM2/MDM4 family protein binding molecular_function 4 3 CDK5RAP3,PSME3,RFWD3 0.79 0.02589 0.376983658536585 GO:0001047 core promoter binding molecular_function 156 41 AGO1,AGO2,ATF4,BAZ2A,CHD2,CIART,CREM,E2F7,ESR1,EZH2,GTF2B,H2AFY,HDAC1,HDAC2,HDAC6,HEYL,HMGA2,HNRNPU,KANSL1,KANSL1L,KMT2A,MEF2C,MTA1,NFYA,NLRC5,PRMT5,RBMX,RBPJ,SFPQ,SMYD3,SP1,SP3,STAT6,TAF1B,TAF1C,TCF7,THRAP3,UBTF,USP3,ZNF277,ZNF431 30.67 0.02617 0.378751272727273 GO:0005178 integrin binding molecular_function 104 29 ACTN1,ADAM10,ADAM22,ADAM23,ANGPTL3,ANXA7,CD9,CIB2,COL4A3,CXADR,EGFR,FBLN5,FBN1,FCER2,ITGA2,ITGA6,ITGB1BP1,ITGB6,JAM3,MFGE8,NISCH,PTPN2,PXN,SEMA7A,THY1,TLN1,TNXB,TSPAN8,WISP2 20.44 0.02658 0.382367710843373 GO:0000339 RNA cap binding molecular_function 13 6 AGO2,EIF4A1,EIF4E,EIF4G3,NCBP2,NCBP3 2.56 0.02768 0.388822588235294 GO:0019789 SUMO transferase activity molecular_function 13 6 HDAC7,MDM2,NSMCE2,PIAS1,RANBP2,SUMO2 2.56 0.02768 0.388822588235294 GO:0030676 Rac guanyl-nucleotide exchange factor ac... molecular_function 13 6 ARHGEF2,EPS8L1,FARP1,FARP2,SPATA13,VAV1 2.56 0.02768 0.388822588235294 GO:0043024 ribosomal small subunit binding molecular_function 13 6 ABCE1,EIF4B,EIF4H,MTIF2,MTIF3,PTCD3 2.56 0.02768 0.388822588235294 GO:0003779 actin binding molecular_function 394 93 ABLIM2,ABLIM3,ACTN1,ACTR2,ACTR3C,ADD3,ANLN,ANTXR1,ARPC1A,ARPC1B,CAPZA1,CCDC88A,COBL,CORO2B,CORO7,CTNNA1,CTNNA3,CYFIP1,DAAM1,DAG1,DNASE1,EGFR,EPB41L3,EPS8L1,EVL,FGD4,FHOD3,FLII,FMN1,FMN2,FMNL2,GCSAM,GMFB,GMFG,GSN,HDAC6,HOOK1,IMPACT,INO80,IPP,KCNMA1,KLHL20,KLHL3,KLHL5,LCP1,LIMCH1,LRPPRC,LSP1,MAEA,MAP1S,MLPH,MYBPC1,MYH10,MYH9,MYLK,MYO10,MYO16,MYO18A,MYO1B,MYO1F,MYO1G,MYO3B,MYOZ3,NEB,NOS3,PALLD,PARVG,PAWR,PFN2,PICK1,PKNOX2,PPP1R42,PTK2,RP2,SHTN1,SMTN,SNTG2,SPTB,SPTBN1,SPTBN4,SSFA2,SYNE1,SYNPO,SYNPO2,TLN1,TNNI3,TNNT2,TNS1,TRIOBP,TRPM7,TWF1,USH1C,VIL1 77.45 0.02862 0.399675789473684 GO:0016814 hydrolase activity, acting on carbon-nit... molecular_function 35 12 ADA,ADAD2,ADAT2,AMPD3,APOBEC3B,APOBEC3F,ATIC,CECR1,DCTD,GDA,MTHFD1,MTHFD2L 6.88 0.03025 0.409613770491803 GO:0004596 peptide alpha-N-acetyltransferase activi... molecular_function 10 5 NAA10,NAA16,NAA20,NAA25,NAA60 1.97 0.03054 0.409613770491803 GO:0016423 tRNA (guanine) methyltransferase activit... molecular_function 10 5 METTL1,TARBP1,THUMPD3,TRMT10C,TRMT1L 1.97 0.03054 0.409613770491803 GO:0043995 histone acetyltransferase activity (H4-K... molecular_function 10 5 KANSL1,KANSL1L,KANSL2,OGT,PHF20 1.97 0.03054 0.409613770491803 GO:0043996 histone acetyltransferase activity (H4-K... molecular_function 10 5 KANSL1,KANSL1L,KANSL2,OGT,PHF20 1.97 0.03054 0.409613770491803 GO:0046972 histone acetyltransferase activity (H4-K... molecular_function 10 5 KANSL1,KANSL1L,KANSL2,OGT,PHF20 1.97 0.03054 0.409613770491803 GO:0019900 kinase binding molecular_function 588 134 ACE,ADAM10,ADIPOR1,AKAP7,AKT1,ANGPT2,ANK2,APPL1,ARHGEF16,ATF2,AURKA,BCAR1,BCL2L14,BLNK,BORA,BRAF,C1QBP,CACNB3,CACUL1,CALM1,CCDC88A,CCNE2,CCNL2,CDC42,CDC6,CDK5RAP3,CENPJ,CLTC,CPNE3,CTNND1,CYLD,DAB2IP,DLG2,DLG3,DOCK4,EGFR,ELP2,FAF1,FAM150A,FAM83E,FAS,FBXO7,FEZ1,FGFR1OP,FNTA,FRS2,GCSAM,GPRC5B,GRB7,GSK3B,GSTP1,GTF2I,GYS1,H2AFY,HDAC7,HDAC9,ITGAV,ITGB1BP1,KAT2B,KIZ,LAT,MAP2K3,MAP2K4,MAP2K7,MAP3K12,MAP3K2,MAP4K2,MAPK4,MAPK8IP3,MARVELD3,MEF2A,MIDN,MTOR,MVP,MYOC,NCK1,NFATC1,PAK1,PAK2,PARN,PDCD10,PDGFRB,PFKFB1,PICK1,PIK3R2,PIN1,PIP5K1A,PKP2,POLA1,PPP1CB,PPP1CC,PPP1R12A,PPP1R12B,PRC1,PRKAR2A,PRKCZ,PRMT1,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRK,PXN,RAB11FIP2,RACGAP1,RGS14,RNF138,RPS19,RYR2,SASH1,SGO1,SHC2,SNAP91,SPAG16,SPAG9,SPDYA,SRSF5,TAX1BP1,TELO2,TEX14,THY1,TNNI3,TNS2,TOM1L1,TOP2B,TPRKB,TRADD,TRAF4,TRIM5,TRIP6,WDCP,WWC2,YWHAZ 115.59 0.03069 0.409613770491803 GO:0001076 transcription factor activity, RNA polym... molecular_function 140 37 ATF2,ATF4,CNOT2,CTBP1,DMTF1,ELP2,HDAC1,HEYL,JADE1,LIF,LMO2,MED12L,MED13,MED13L,MED14,MED21,MED24,MED30,MED31,MEF2A,MYB,NCOA1,NFE2L1,NR3C1,PHF12,PRRX1,RBBP8,SMAD4,SMARCA2,SNAPC4,TAF2,TBX20,TCERG1,THRAP3,TTF1,WWOX,ZNF451 27.52 0.03075 0.409613770491803 GO:0019901 protein kinase binding molecular_function 522 120 ACE,ADAM10,ADIPOR1,AKAP7,AKT1,ANGPT2,ANK2,APPL1,ARHGEF16,ATF2,AURKA,BCAR1,BCL2L14,BLNK,BORA,BRAF,C1QBP,CACNB3,CACUL1,CALM1,CCDC88A,CCNE2,CCNL2,CDC42,CDK5RAP3,CENPJ,CLTC,CPNE3,CTNND1,CYLD,DAB2IP,DOCK4,EGFR,ELP2,FAF1,FAM150A,FAM83E,FBXO7,FEZ1,FGFR1OP,FNTA,FRS2,GCSAM,GPRC5B,GRB7,GSK3B,GSTP1,GTF2I,GYS1,H2AFY,HDAC7,HDAC9,ITGAV,ITGB1BP1,KAT2B,KIZ,LAT,MAP2K3,MAP2K4,MAP2K7,MAP3K12,MAP3K2,MAP4K2,MAPK4,MAPK8IP3,MARVELD3,MEF2A,MTOR,MVP,MYOC,NCK1,NFATC1,PAK1,PAK2,PARN,PDCD10,PDGFRB,PICK1,PIK3R2,PIN1,PKP2,POLA1,PPP1CB,PPP1CC,PPP1R12A,PPP1R12B,PRC1,PRKAR2A,PRKCZ,PRMT1,PTEN,PTK2,PTK2B,PTPN2,PTPN6,PTPRK,PXN,RAB11FIP2,RACGAP1,RGS14,RNF138,RPS19,RYR2,SASH1,SHC2,SNAP91,SPAG16,SPAG9,SPDYA,SRSF5,TELO2,TEX14,THY1,TNNI3,TOM1L1,TOP2B,TPRKB,TRAF4,TRIM5,YWHAZ 102.61 0.03100 0.409613770491803 GO:0004586 ornithine decarboxylase activity molecular_function 7 4 AZIN2,OAZ1,OAZ2,PRLR 1.38 0.03139 0.409613770491803 GO:0008432 JUN kinase binding molecular_function 7 4 GSTP1,MAPK8IP3,PTK2,SPAG9 1.38 0.03139 0.409613770491803 GO:0071933 Arp2/3 complex binding molecular_function 7 4 GMFB,GMFG,PICK1,SNX9 1.38 0.03139 0.409613770491803 GO:0004517 nitric-oxide synthase activity molecular_function 47 15 AKT1,ATP2B4,CALM1,DHFR,EGFR,ESR1,FCER2,GLA,HTR2B,IL1B,KRAS,LYPLA1,NOS3,PTK2B,PTS 9.24 0.03167 0.41102152173913 GO:0016741 transferase activity, transferring one-c... molecular_function 221 55 ALDH1L1,AMT,ASH1L,ATIC,CMTR2,CPS1,DIMT1,DOT1L,DPH5,EHMT1,EHMT2,EZH2,FBL,FBXO11,FTCD,GART,GCSH,KMT2A,KMT2D,KMT2E,LCMT1,METTL1,METTL14,METTL15,METTL16,METTL21A,METTL22,METTL23,METTL5,NDUFAF7,NOP2,NSUN4,NSUN7,PCMT1,PCMTD1,PNMT,PRDM16,PRMT1,PRMT3,PRMT5,RRNAD1,RRP8,SHMT2,SMYD2,SMYD3,TARBP1,TFB1M,THUMPD3,TRMT10A,TRMT10C,TRMT13,TRMT1L,TYMS,WHSC1,WHSC1L1 43.44 0.03236 0.411823392857143 GO:0001671 ATPase activator activity molecular_function 17 7 AHSA2,ATP1B1,DNAJC1,DNAJC10,DNAJC24,TOR1AIP1,TOR1AIP2 3.34 0.03448 0.411823392857143 GO:0003995 acyl-CoA dehydrogenase activity molecular_function 17 7 ACAD11,ACAD8,ACADVL,ACOX3,ACOXL,ETFA,TECR 3.34 0.03448 0.411823392857143 GO:0008187 poly-pyrimidine tract binding molecular_function 17 7 HNRNPC,HNRNPH1,MSI1,MSI2,PABPC1,PNPT1,RBM11 3.34 0.03448 0.411823392857143 GO:0008331 high voltage-gated calcium channel activ... molecular_function 17 7 CACNA1A,CACNA1C,CACNA1S,CACNA2D1,CACNB3,CALM1,SRI 3.34 0.03448 0.411823392857143 GO:0010485 H4 histone acetyltransferase activity molecular_function 17 7 HAT1,KANSL1,KANSL1L,KANSL2,NAA60,OGT,PHF20 3.34 0.03448 0.411823392857143 GO:0016646 oxidoreductase activity, acting on the C... molecular_function 17 7 ALDH1L1,CRYM,DHFR,MTHFD1,MTHFD2L,PYCR1,QDPR 3.34 0.03448 0.411823392857143 GO:0030275 LRR domain binding molecular_function 17 7 ATF4,DAPK3,ERC1,KRAS,LRRFIP2,PAWR,ROBO1 3.34 0.03448 0.411823392857143 GO:0031435 mitogen-activated protein kinase kinase ... molecular_function 17 7 CDC42,DAB2IP,MAP2K4,MAP4K2,MAPK8IP3,MARVELD3,SASH1 3.34 0.03448 0.411823392857143 GO:0042578 phosphoric ester hydrolase activity molecular_function 562 128 ACP1,ADORA1,AIP,ALPL,ALPP,ANKLE2,ARPP19,BAG4,BICD1,BMP2K,BPNT1,CABIN1,CALM1,CAMK2G,CAMSAP3,CD2BP2,CDC14B,CDK5RAP3,CDKN3,CEP192,CNST,CSRNP3,CTDNEP1,CTDSPL2,DLG2,DLG3,DMPK,DUSP13,DUSP16,DUSP9,EGFR,EIF2AK2,ENOPH1,ENPP2,ESR1,EYA3,EYA4,FARP1,FGFR1,FRS2,GDPD1,HDHD2,HSP90B1,HTR2B,INPP1,INPP5A,INPP5B,ITGA2,LPIN1,MASTL,MEF2C,MPHOSPH10,MPPE1,MTMR1,MTMR7,NAPEPLD,NSMAF,NT5C2,NT5C3B,NT5DC1,OCRL,PDE1B,PDE2A,PDE4D,PDE5A,PDE6B,PDE6D,PDE8A,PDE9A,PDGFRB,PFKFB1,PGAP1,PLCB1,PLCB2,PLCB4,PLCD3,PLCD4,PLCH1,PLD1,PLPP5,PLPPR2,PNKP,PON1,PPIP5K1,PPIP5K2,PPM1B,PPM1M,PPP1CB,PPP1CC,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP6R3,PPTC7,PTEN,PTP4A2,PTPN13,PTPN2,PTPN20,PTPN6,PTPRA,PTPRK,PTPRN,PTPRT,PXYLP1,RASGRP4,RGN,SACM1L,SBF1,SEMA4D,SYTL2,TDP1,TIGAR,TIMM50,TNS2,UBLCP1 110.48 0.03456 0.411823392857143 GO:0000980 RNA polymerase II distal enhancer sequen... molecular_function 64 19 ACTL6A,ATF2,ESRRB,GATAD2B,GZF1,HDAC1,HDAC2,HNRNPC,MBD3,MEF2C,NFATC1,NFE2L1,NFE2L2,PAX4,RBBP4,SFPQ,SIX3,SMARCD2,SMARCE1 12.58 0.03566 0.411823392857143 GO:0050839 cell adhesion molecule binding molecular_function 182 46 ACTN1,ADAM10,ADAM22,ADAM23,ANGPTL3,ANK3,ANXA7,CD200,CD46,CD9,CDH1,CDH13,CIB2,CLDN7,COL4A3,CTNNA1,CTNNA3,CTNND1,CXADR,DSG2,EGFR,FBLN5,FBN1,FCER2,ITGA2,ITGA6,ITGAL,ITGB1BP1,ITGB6,JAM3,MFGE8,NECTIN1,NISCH,NLGN3,NRXN1,PROM1,PTPN2,PTPN6,PTPRT,PXN,SEMA7A,THY1,TLN1,TNXB,TSPAN8,WISP2 35.78 0.03700 0.411823392857143 GO:0000248 C-5 sterol desaturase activity molecular_function 2 2 FADS1,SC5D 0.39 0.03863 0.411823392857143 GO:0001224 RNA polymerase II transcription cofactor... molecular_function 2 2 CNOT2,NFATC1 0.39 0.03863 0.411823392857143 GO:0003835 beta-galactoside alpha-2,6-sialyltransfe... molecular_function 2 2 ST6GAL1,ST6GAL2 0.39 0.03863 0.411823392857143 GO:0004047 aminomethyltransferase activity molecular_function 2 2 AMT,GCSH 0.39 0.03863 0.411823392857143 GO:0004357 glutamate-cysteine ligase activity molecular_function 2 2 GCLC,GCLM 0.39 0.03863 0.411823392857143 GO:0004530 deoxyribonuclease I activity molecular_function 2 2 DICER1,DNASE1 0.39 0.03863 0.411823392857143 GO:0004569 glycoprotein endo-alpha-1,2-mannosidase ... molecular_function 2 2 EDEM3,MANEA 0.39 0.03863 0.411823392857143 GO:0004815 aspartate-tRNA ligase activity molecular_function 2 2 DARS,DARS2 0.39 0.03863 0.411823392857143 GO:0004830 tryptophan-tRNA ligase activity molecular_function 2 2 WARS,WARS2 0.39 0.03863 0.411823392857143 GO:0004910 interleukin-1, Type II, blocking recepto... molecular_function 2 2 IL1R2,IL1RAPL2 0.39 0.03863 0.411823392857143 GO:0004991 parathyroid hormone receptor activity molecular_function 2 2 PTH1R,PTH2R 0.39 0.03863 0.411823392857143 GO:0004998 transferrin receptor activity molecular_function 2 2 TFR2,TFRC 0.39 0.03863 0.411823392857143 GO:0005011 macrophage colony-stimulating factor rec... molecular_function 2 2 CSF1R,MST1R 0.39 0.03863 0.411823392857143 GO:0008988 rRNA (adenine-N6-)-methyltransferase act... molecular_function 2 2 DIMT1,METTL16 0.39 0.03863 0.411823392857143 GO:0010698 acetyltransferase activator activity molecular_function 2 2 BCAS3,PDCD5 0.39 0.03863 0.411823392857143 GO:0019781 NEDD8 activating enzyme activity molecular_function 2 2 NAE1,UBA3 0.39 0.03863 0.411823392857143 GO:0019948 SUMO activating enzyme activity molecular_function 2 2 SAE1,UBA2 0.39 0.03863 0.411823392857143 GO:0030171 voltage-gated proton channel activity molecular_function 2 2 HVCN1,NOX1 0.39 0.03863 0.411823392857143 GO:0030586 [methionine synthase] reductase activity molecular_function 2 2 MTRR,POR 0.39 0.03863 0.411823392857143 GO:0033570 transferrin transmembrane transporter ac... molecular_function 2 2 SLC11A2,TFRC 0.39 0.03863 0.411823392857143 GO:0033857 diphosphoinositol-pentakisphosphate kina... molecular_function 2 2 PPIP5K1,PPIP5K2 0.39 0.03863 0.411823392857143 GO:0034057 RNA strand-exchange activity molecular_function 2 2 EIF4B,EIF4H 0.39 0.03863 0.411823392857143 GO:0038062 protein tyrosine kinase collagen recepto... molecular_function 2 2 DDR1,DDR2 0.39 0.03863 0.411823392857143 GO:0042903 tubulin deacetylase activity molecular_function 2 2 HDAC6,SIRT2 0.39 0.03863 0.411823392857143 GO:0060698 endoribonuclease inhibitor activity molecular_function 2 2 ABCE1,TMBIM6 0.39 0.03863 0.411823392857143 GO:0070704 sterol desaturase activity molecular_function 2 2 FADS1,SC5D 0.39 0.03863 0.411823392857143 GO:0072320 volume-sensitive chloride channel activi... molecular_function 2 2 CLCN3,TTYH1 0.39 0.03863 0.411823392857143 GO:0097003 adipokinetic hormone receptor activity molecular_function 2 2 ADIPOR1,ADIPOR2 0.39 0.03863 0.411823392857143 GO:0008080 N-acetyltransferase activity molecular_function 90 25 ATAT1,ATF2,BAZ1A,ELP4,HAT1,HGSNAT,KANSL1,KANSL1L,KANSL2,KAT2B,KAT6A,KAT7,MED24,NAA10,NAA16,NAA20,NAA25,NAA60,NAT1,NAT10,NCOA1,NCOA2,OGT,PHF20,SMARCE1 17.69 0.03911 0.413673451327434 GO:0004972 NMDA glutamate receptor activity molecular_function 21 8 CNIH2,CRHBP,DAPK1,MEF2C,NLGN3,OPRM1,PTK2B,RELN 4.13 0.03915 0.413673451327434 GO:0008022 protein C-terminus binding molecular_function 174 44 AGO2,ATF4,ATP1B1,ATXN2,BAIAP3,CDK7,CEP135,CTBP1,DAPK3,DLG3,EML2,FBLN5,FOXN3,HESX1,HOMER3,ITGB3BP,LIG4,MAGI1,MID1IP1,MKI67,MPDZ,NIPBL,OPRM1,PABPC1,PDZD3,PEX16,PIAS1,PICK1,PPP1CC,SAE1,SASH1,SDCBP,SIPA1,SP1,SYT1,TOP2B,TOPBP1,USP7,VPS36,VPS4A,VTA1,XRCC5,YEATS4,YWHAQ 34.2 0.04030 0.423948898678414 GO:0019201 nucleotide kinase activity molecular_function 25 9 AK2,AK6,CASK,CMPK1,DLG2,DLG3,DTYMK,GUK1,PNKP 4.91 0.04227 0.440789344978166 GO:0022884 macromolecule transmembrane transporter ... molecular_function 25 9 AZIN2,GPIHBP1,HNRNPA3,SIDT1,SIDT2,SLC11A2,TFRC,TIMM23B,TOMM20 4.91 0.04227 0.440789344978166 GO:0008536 Ran GTPase binding molecular_function 29 10 CSE1L,IPO11,IPO8,IPO9,NUP50,RANBP2,TNPO1,XPO1,XPO7,XPOT 5.7 0.04424 0.459326608695652 GO:0004112 cyclic-nucleotide phosphodiesterase acti... molecular_function 33 11 AIP,CALM1,PDE1B,PDE2A,PDE4D,PDE5A,PDE6B,PDE6D,PDE8A,PDE9A,RGN 6.49 0.04537 0.46901974025974 GO:0034062 RNA polymerase activity molecular_function 45 14 CRCP,EIF4A2,MED21,POLA1,POLR1D,POLR2E,POLR2G,POLR2H,POLR2I,POLR2J3,POLR2K,POLR3C,POLR3F,PRIM1 8.85 0.04563 0.469674310344828 GO:0001056 RNA polymerase III activity molecular_function 18 7 CRCP,POLR1D,POLR2E,POLR2H,POLR2K,POLR3C,POLR3F 3.54 0.04710 0.474577215189873 GO:0016273 arginine N-methyltransferase activity molecular_function 11 5 FBXO11,NDUFAF7,PRMT1,PRMT3,PRMT5 2.16 0.04710 0.474577215189873 GO:0016274 protein-arginine N-methyltransferase act... molecular_function 11 5 FBXO11,NDUFAF7,PRMT1,PRMT3,PRMT5 2.16 0.04710 0.474577215189873 GO:0016723 oxidoreductase activity, oxidizing metal... molecular_function 11 5 CYB561,MTRR,POR,STEAP1B,STEAP4 2.16 0.04710 0.474577215189873 GO:0017154 semaphorin receptor activity molecular_function 11 5 NRP2,PLXNA1,PLXNB1,PLXNC1,PLXND1 2.16 0.04710 0.474577215189873 GO:0032947 protein complex scaffold molecular_function 66 19 C9orf142,CD3G,CHCHD3,EIF3B,LAMTOR1,LAMTOR3,LDLRAP1,MAGI1,MAPK8IP3,NCK1,PKP2,RGS14,SASH1,SEPT2,SHANK2,SMARCD1,SPAG9,TELO2,WWC2 12.97 0.04778 0.4787989958159 GO:0004707 MAP kinase activity molecular_function 328 77 ADORA1,BIRC7,BRAF,CD74,CD81,CDK12,CDK5RAP3,CHRNA7,DAB2IP,DNAJA1,DUSP16,DUSP9,EGF,EGFR,EIF2AK2,EPHA4,EZH2,FGFR1,FRS2,GADD45G,GSTP1,HACD3,HGS,HIPK3,HTR2B,IGF1R,IL1B,IRAK1,KRAS,LAMTOR3,MADD,MAGED1,MAP2K3,MAP2K4,MAP2K5,MAP2K7,MAP3K12,MAP3K2,MAP3K3,MAP4K1,MAP4K2,MAPK4,MAPK8,MAPK8IP3,MAPKAPK5,MST1R,NEK10,NF1,NOX4,NTRK3,PAK1,PAK3,PAQR3,PDCD10,PDE5A,PDGFRB,PIK3CB,PIK3R5,PPP2R1A,PTK2B,PTPN6,RAP1A,RGS14,RGS3,SASH1,SHC2,SORL1,SPAG9,SPRY1,TAB2,TAB3,TGFA,TGFB1,TGFBR1,TLR9,UBA52,VEGFA 64.48 0.04792 0.4787989958159 GO:0016791 phosphatase activity molecular_function 427 98 ACP1,ALPL,ALPP,ANKLE2,ARPP19,BAG4,BMP2K,BPNT1,CABIN1,CALM1,CAMK2G,CAMSAP3,CD2BP2,CDC14B,CDK5RAP3,CDKN3,CEP192,CNST,CSRNP3,CTDNEP1,CTDSPL2,DLG2,DLG3,DMPK,DUSP13,DUSP16,DUSP9,EIF2AK2,ENOPH1,EYA3,EYA4,FARP1,FRS2,HDHD2,HSP90B1,INPP1,INPP5A,INPP5B,ITGA2,LPIN1,MASTL,MEF2C,MPHOSPH10,MTMR1,MTMR7,NT5C2,NT5C3B,NT5DC1,OCRL,PDGFRB,PFKFB1,PLPP5,PLPPR2,PNKP,PON1,PPIP5K1,PPIP5K2,PPM1B,PPM1M,PPP1CB,PPP1CC,PPP1R12A,PPP1R12B,PPP1R1B,PPP1R2P3,PPP1R42,PPP1R7,PPP1R8,PPP2R1A,PPP2R2A,PPP2R2C,PPP2R3B,PPP2R5C,PPP2R5E,PPP4C,PPP4R1,PPP6R3,PPTC7,PTEN,PTP4A2,PTPN13,PTPN2,PTPN20,PTPN6,PTPRA,PTPRK,PTPRN,PTPRT,PXYLP1,RGN,SACM1L,SBF1,SEMA4D,SYTL2,TIGAR,TIMM50,TNS2,UBLCP1 83.94 0.04899 0.483723076923077