{"text_format":"2","workbook":"xlsx","n_sheets":3,"sheets":["Trp53WT","Trp53-null","Cdkn1a-null"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Trp53WT","index":0,"n_rows":180,"n_cols":6,"rows_kept":180,"cut":false,"hidden":false,"merged":[]}
["Upstream Regulator","Expr Fold Change","Molecule Type","Predicted Activation State","Activation z-score","p-value of overlap"]
["IL10RA"," ","transmembrane receptor","Inhibited",-3.9169999999999998,9.6199999999999994E-5]
["mir-21"," ","microrna","Inhibited",-3.4620000000000002,9.6899999999999997E-5]
["SCAP",1.3340000000000001,"other","Inhibited",-3.274,1.5100000000000001E-4]
["KDM5A"," ","transcription regulator","Inhibited",-3.1619999999999999,0.154]
["EGFR"," ","kinase","Inhibited",-3.145,0.11]
["TRIM24"," ","transcription regulator","Inhibited",-2.8849999999999998,1.7600000000000001E-3]
["GFI1"," ","transcription regulator","Inhibited",-2.8279999999999998,3.44E-2]
["NCSTN"," ","peptidase","Inhibited",-2.8130000000000002,5.9999999999999995E-4]
["SOCS1"," ","other","Inhibited",-2.778,4.7100000000000003E-2]
["CD3"," ","complex","Inhibited",-2.7360000000000002,4.53E-2]
["SMTNL1"," ","other","Inhibited",-2.6459999999999999,1.3500000000000001E-3]
["MYC"," ","transcription regulator","Inhibited",-2.6110000000000002,7.0900000000000005E-2]
["PTGER2"," ","g-protein coupled receptor","Inhibited",-2.5139999999999998,2.0200000000000001E-3]
["CHD4"," ","enzyme","Inhibited",-2.4489999999999998,7.22E-2]
["HSF1"," ","transcription regulator","Inhibited",-2.4,0.24399999999999999]
["INSR"," ","kinase","Inhibited",-2.3380000000000001,2.1199999999999999E-3]
["Alpha catenin"," ","group","Inhibited",-2.2589999999999999,0.125]
["HOXD10"," ","transcription regulator","Inhibited",-2.2360000000000002,0.13200000000000001]
["FOXA2"," ","transcription regulator","Inhibited",-2.2189999999999999,1]
["NPC1",1.2210000000000001,"transporter","Inhibited",-2.1819999999999999,1.2500000000000001E-5]
["KDM1A"," ","enzyme","Inhibited",-2.177,0.13200000000000001]
["APOE"," ","transporter","Inhibited",-2.1360000000000001,3.7399999999999999E-7]
["PSEN1"," ","peptidase","Inhibited",-2.016,0.433]
["RRM2B"," ","enzyme","Inhibited",-2,1.2999999999999999E-5]
["RPL22",-1.256,"other","Inhibited",-2,1.7699999999999999E-4]
["DBI"," ","other","Inhibited",-2,3.9300000000000001E-4]
["STAR"," ","transporter","Inhibited",-2,4.3600000000000002E-3]
["MYT1"," ","transcription regulator","Inhibited",-2,1.6500000000000001E-2]
["BCL3"," ","transcription regulator","Inhibited",-2,2.4400000000000002E-2]
["SOX2"," ","transcription regulator"," ",-1.992,1]
["TOPBP1"," ","other"," ",-1.9870000000000001,7.4899999999999999E-4]
["ATG7"," ","enzyme"," ",-1.9690000000000001,0.113]
["RBPJ"," ","transcription regulator"," ",-1.9690000000000001,0.33600000000000002]
["ATP7B"," ","transporter"," ",-1.897,7.6100000000000007E-5]
["APP"," ","other"," ",-1.8380000000000001,2.1899999999999999E-2]
["HOXA3"," ","transcription regulator"," ",-1.609,2.3699999999999999E-2]
["IL4"," ","cytokine"," ",-1.5649999999999999,8.2700000000000004E-4]
["PTPN11"," ","phosphatase"," ",-1.528,9.4599999999999992E-6]
["EP400"," ","other"," ",-1.3420000000000001,1.2800000000000001E-2]
["PTGER4"," ","g-protein coupled receptor"," ",-1.278,5.7800000000000004E-3]
["STAT5A"," ","transcription regulator"," ",-1.2110000000000001,2.1299999999999999E-2]
["ACTL6A"," ","other"," ",-1.1339999999999999,2.92E-4]
["JUN"," ","transcription regulator"," ",-1.103,3.13E-3]
["TGFB1"," ","growth factor"," ",-1.0920000000000001,2.69E-2]
["CREB1",-1.1830000000000001,"transcription regulator"," ",-1.0669999999999999,3.1900000000000001E-3]
["STAT5B"," ","transcription regulator"," ",-1.0660000000000001,2.9100000000000001E-2]
["OSBPL8"," ","transporter"," ",-1,2.0400000000000001E-3]
["PTCH1"," ","transmembrane receptor"," ",-1,1.06E-2]
["DCN"," ","other"," ",-1,1.6500000000000001E-2]
["Cyp2c44"," ","enzyme"," ",-0.95799999999999996,2.0199999999999999E-2]
["Il3"," ","cytokine"," ",-0.77500000000000002,4.5799999999999999E-3]
["CSF2"," ","cytokine"," ",-0.71499999999999997,1.8200000000000001E-4]
["NR1H2"," ","ligand-dependent nuclear receptor"," ",-0.627,1.5299999999999999E-2]
["Nr1h"," ","group"," ",-0.46100000000000002,2.8899999999999999E-2]
["PPARD",1.3779999999999999,"ligand-dependent nuclear receptor"," ",-0.439,1.8499999999999999E-2]
["RUNX1"," ","transcription regulator"," ",-0.41799999999999998,3.44E-2]
["Irgm1"," ","other"," ",-0.378,1.35E-2]
["HIPK2"," ","kinase"," ",-0.378,4.9700000000000001E-2]
["CBFB"," ","transcription regulator"," ",-0.33300000000000002,1.5299999999999999E-2]
["STAT3"," ","transcription regulator"," ",-0.3,5.3200000000000001E-3]
["LYN"," ","kinase"," ",-0.27700000000000002,2.6499999999999999E-2]
["NHLH2"," ","other"," ",-0.152,6.0000000000000001E-3]
["Cdc42"," ","enzyme"," ",-0.13700000000000001,3.5600000000000001E-8]
["HDAC2"," ","transcription regulator"," ",0,3.2699999999999999E-3]
["NQO1"," ","enzyme"," ",0,1.47E-2]
["mir-193"," ","microrna"," ",0,2.4400000000000002E-2]
["SPP1"," ","cytokine"," ",0,3.1099999999999999E-2]
["REL"," ","transcription regulator"," ",2.7E-2,1.0499999999999999E-3]
["ENG"," ","transmembrane receptor"," ",0.152,2.9100000000000001E-2]
["STAT6"," ","transcription regulator"," ",0.20399999999999999,1.7900000000000001E-5]
["HDAC1"," ","transcription regulator"," ",0.24299999999999999,2.0400000000000001E-3]
["CYLD"," ","transcription regulator"," ",0.29499999999999998,4.0599999999999997E-2]
["PPARG"," ","ligand-dependent nuclear receptor"," ",0.313,3.1E-2]
["TP63"," ","transcription regulator"," ",0.42599999999999999,1.26E-2]
["PPIF"," ","enzyme"," ",0.83199999999999996,4.4299999999999999E-3]
["BTK",1.7490000000000001,"kinase"," ",0.84599999999999997,3.85E-2]
["INSIG1"," ","other"," ",0.89200000000000002,2.2299999999999998E-6]
["MMP9"," ","peptidase"," ",0.89800000000000002,2.5900000000000002E-6]
["C3AR1",2.0499999999999998,"g-protein coupled receptor"," ",0.92800000000000005,1.6899999999999998E-2]
["LTBR",1.43,"transmembrane receptor"," ",0.94599999999999995,2.7799999999999998E-2]
["CD47"," ","transmembrane receptor"," ",0.97499999999999998,1.04E-2]
["ID2"," ","transcription regulator"," ",1,0.01]
["LEP"," ","growth factor"," ",1.0229999999999999,2.3300000000000001E-2]
["PPARA"," ","ligand-dependent nuclear receptor"," ",1.048,9.8999999999999994E-5]
["NR1H3",1.905,"ligand-dependent nuclear receptor"," ",1.0489999999999999,2.8700000000000002E-3]
["NLRP3"," ","other"," ",1.1339999999999999,4.7100000000000003E-2]
["UTS2R"," ","g-protein coupled receptor"," ",1.1719999999999999,3.7499999999999997E-5]
["PPARGC1A"," ","transcription regulator"," ",1.2,3.9899999999999998E-2]
["CSF1",2,"cytokine"," ",1.2310000000000001,1.35E-2]
["CCR2"," ","g-protein coupled receptor"," ",1.276,2.01E-2]
["LDLR"," ","transporter"," ",1.28,4.65E-2]
["MYB"," ","transcription regulator"," ",1.4079999999999999,1.6400000000000001E-2]
["EGR1"," ","transcription regulator"," ",1.4650000000000001,1E-3]
["AKT1"," ","kinase"," ",1.51,1.4599999999999999E-3]
["Gm15807/Hmgn5",-2.0110000000000001,"other"," ",1.633,2.49E-3]
["BAX",2.516,"transporter"," ",1.6639999999999999,3.8399999999999997E-2]
["TCF7L2"," ","transcription regulator"," ",1.8069999999999999,1]
["IKBKG"," ","kinase"," ",1.8240000000000001,1.9000000000000001E-4]
["NOD2"," ","other"," ",1.8420000000000001,6.1199999999999997E-2]
["RETNLB"," ","other"," ",1.89,0.156]
["CFTR"," ","ion channel"," ",1.897,2.9199999999999999E-3]
["PLG"," ","peptidase"," ",1.9119999999999999,1.7100000000000001E-2]
["VEGFA"," ","growth factor"," ",1.9370000000000001,1.7100000000000001E-2]
["INSIG2"," ","other"," ",1.964,8.0099999999999998E-3]
["TLR7",1.5009999999999999,"transmembrane receptor"," ",1.964,3.5099999999999999E-2]
["NR1I3"," ","ligand-dependent nuclear receptor"," ",1.9670000000000001,7.3099999999999998E-2]
["Ccl2"," ","cytokine"," ",1.9670000000000001,0.313]
["VIPR1"," ","g-protein coupled receptor"," ",1.9690000000000001,1.7699999999999999E-4]
["Fcer1"," ","complex"," ",1.9690000000000001,7.5899999999999995E-2]
["IRF1",1.3440000000000001,"transcription regulator"," ",1.9690000000000001,0.437]
["CEBPA"," ","transcription regulator"," ",1.9770000000000001,0.16900000000000001]
["TRPV4"," ","ion channel"," ",1.982,0.04]
["PRKCB"," ","kinase"," ",1.982,6.0100000000000001E-2]
["TBK1"," ","kinase"," ",1.982,0.54200000000000004]
["IgG"," ","complex","Activated",2,6.2000000000000003E-5]
["NPC1L1"," ","transporter","Activated",2,1.7699999999999999E-4]
["CYP51A1",-1.8859999999999999,"enzyme","Activated",2,6.0000000000000001E-3]
["COL6A1"," ","other","Activated",2,8.0099999999999998E-3]
["BID"," ","other","Activated",2,1.04E-2]
["IFNGR1"," ","transmembrane receptor","Activated",2,2.1899999999999999E-2]
["IRAK4"," ","kinase","Activated",2,9.4600000000000004E-2]
["ARHGAP21"," ","other","Activated",2,0.25800000000000001]
["DOCK8"," ","other","Activated",2,1]
["SASH1"," ","other","Activated",2,1]
["IL1B"," ","cytokine","Activated",2.0459999999999998,0.105]
["TLR9",1.611,"transmembrane receptor","Activated",2.0950000000000002,0.106]
["TNFRSF1A",1.375,"transmembrane receptor","Activated",2.1059999999999999,7.26E-3]
["CHEK2"," ","kinase","Activated",2.2000000000000002,4.4499999999999997E-6]
["PARP1"," ","enzyme","Activated",2.2010000000000001,1.1900000000000001E-2]
["IFNAR1"," ","transmembrane receptor","Activated",2.2090000000000001,3.5700000000000003E-2]
["TNFRSF1B",2.081,"transmembrane receptor","Activated",2.2130000000000001,0.38900000000000001]
["PEX5L"," ","ion channel","Activated",2.2160000000000002,6.6799999999999997E-4]
["IL12 (complex)"," ","complex","Activated",2.2189999999999999,0.254]
["FOXO1"," ","transcription regulator","Activated",2.2189999999999999,1]
["AR"," ","ligand-dependent nuclear receptor","Activated",2.2189999999999999,1]
["CCR1"," ","g-protein coupled receptor","Activated",2.2360000000000002,8.6999999999999994E-3]
["BNIP3L"," ","other","Activated",2.2360000000000002,0.21199999999999999]
["NFATC2"," ","transcription regulator","Activated",2.2360000000000002,0.53200000000000003]
["SAMSN1"," ","other","Activated",2.2360000000000002,1]
["RB1"," ","transcription regulator","Activated",2.242,4.58E-2]
["NFkB (complex)"," ","complex","Activated",2.2799999999999998,1.7600000000000001E-3]
["IRF8"," ","transcription regulator","Activated",2.3140000000000001,1.5900000000000001E-3]
["SRF"," ","transcription regulator","Activated",2.407,0.34499999999999997]
["SPI1",1.8049999999999999,"transcription regulator","Activated",2.4079999999999999,2.5399999999999999E-2]
["SPIB"," ","transcription regulator","Activated",2.4140000000000001,0.33900000000000002]
["FDFT1"," ","enzyme","Activated",2.4329999999999998,4.6299999999999998E-4]
["CASZ1"," ","enzyme","Activated",2.4329999999999998,1.0999999999999999E-2]
["MEF2C"," ","transcription regulator","Activated",2.4329999999999998,4.24E-2]
["CCR5"," ","g-protein coupled receptor","Activated",2.4350000000000001,1.2800000000000001E-2]
["ZBTB33"," ","other","Activated",2.4489999999999998,1.1799999999999999E-6]
["TFEB"," ","transcription regulator","Activated",2.4489999999999998,2.22E-4]
["TLR3"," ","transmembrane receptor","Activated",2.488,1.5599999999999999E-2]
["IFN alpha/beta"," ","group","Activated",2.5430000000000001,1.4599999999999999E-3]
["Interferon alpha"," ","group","Activated",2.5859999999999999,5.0200000000000002E-3]
["C5AR1"," ","g-protein coupled receptor","Activated",2.5880000000000001,1.35E-2]
["IL13"," ","cytokine","Activated",2.589,4.26E-4]
["RIPK2"," ","kinase","Activated",2.6339999999999999,5.7999999999999996E-3]
["mir-223"," ","microrna","Activated",2.6459999999999999,0.27100000000000002]
["MAPK14"," ","kinase","Activated",2.7440000000000002,2.0200000000000001E-3]
["P38 MAPK"," ","group","Activated",2.7719999999999998,2.8199999999999999E-2]
["MGEA5"," ","enzyme","Activated",2.8279999999999998,5.9100000000000005E-4]
["IL2"," ","cytokine","Activated",2.891,3.78E-2]
["TNF"," ","cytokine","Activated",2.8940000000000001,4.2999999999999997E-2]
["Ifnar"," ","group","Activated",2.9140000000000001,5.7499999999999999E-3]
["IRF7"," ","transcription regulator","Activated",2.9420000000000002,1.3899999999999999E-2]
["DMD"," ","other","Activated",2.9750000000000001,1.82E-3]
["POR"," ","enzyme","Activated",3.05,5.94E-3]
["RELA"," ","transcription regulator","Activated",3.1320000000000001,7.0000000000000007E-2]
["CDKN2A"," ","transcription regulator","Activated",3.2,3.7399999999999998E-3]
["IRF3"," ","transcription regulator","Activated",3.3260000000000001,1.67E-3]
["IFNB1"," ","cytokine","Activated",3.3570000000000002,1.4100000000000001E-6]
["STAT1"," ","transcription regulator","Activated",3.4079999999999999,2.1900000000000001E-4]
["CHUK"," ","kinase","Activated",3.5640000000000001,2.5100000000000001E-2]
["MYD88"," ","other","Activated",3.6179999999999999,1.2E-2]
["TICAM1"," ","other","Activated",3.633,2.6599999999999999E-5]
["TLR4"," ","transmembrane receptor","Activated",3.7810000000000001,1.2200000000000001E-2]
["TP53"," ","transcription regulator","Activated",4.4020000000000001,4.2899999999999999E-15]
["IKBKB"," ","kinase","Activated",4.5190000000000001,1.9499999999999999E-3]
["IFNG"," ","cytokine","Activated",5.5640000000000001,4.3899999999999999E-4]

{"sheet":"Trp53-null","index":1,"n_rows":59,"n_cols":6,"rows_kept":59,"cut":false,"hidden":false,"merged":[]}
["Upstream Regulator","Expr Fold Change","Molecule Type","Predicted Activation State","Activation z-score","p-value of overlap"]
["TRIM24"," ","transcription regulator","Inhibited",-4.3150000000000004,3.0799999999999998E-22]
["ACKR2"," ","g-protein coupled receptor","Inhibited",-4,3.6399999999999998E-25]
["PTGER4"," ","g-protein coupled receptor","Inhibited",-3.9550000000000001,2.4800000000000001E-15]
["SOCS1"," ","other","Inhibited",-3.5630000000000002,1.99E-15]
["STAT3"," ","transcription regulator","Inhibited",-3.032,1.9799999999999999E-13]
["mir-21"," ","microrna","Inhibited",-2.9609999999999999,2.0400000000000001E-8]
["IL10RA"," ","transmembrane receptor","Inhibited",-2.714,1.24E-5]
["Irgm1"," ","other","Inhibited",-2.6459999999999999,2.6700000000000001E-8]
["DNASE2"," ","enzyme","Inhibited",-2.407,3.9500000000000002E-14]
["GFI1"," ","transcription regulator","Inhibited",-2,1.2199999999999999E-3]
["NR3C1"," ","ligand-dependent nuclear receptor","Inhibited",-2,1.04E-2]
["STAT6"," ","transcription regulator"," ",-1.89,1.06E-4]
["Nr1h"," ","group"," ",-1.633,1.5100000000000001E-4]
["IL4"," ","cytokine"," ",-1.486,1.2899999999999999E-4]
["STAT5B"," ","transcription regulator"," ",-1.0669999999999999,5.6299999999999996E-3]
["TBK1"," ","kinase"," ",1,9.89E-10]
["IKBKE"," ","kinase"," ",1.633,1.5799999999999999E-8]
["PARP1"," ","enzyme"," ",1.974,5.8900000000000001E-4]
["NCOA2"," ","transcription regulator"," ",1.976,6.7600000000000003E-5]
["IKBKG"," ","kinase"," ",1.99,1.0800000000000001E-2]
["STAT2",2.6240000000000001,"transcription regulator"," ",2,1.77E-8]
["MAPKAP1"," ","other","Activated",2,9.8500000000000002E-8]
["PLK4"," ","kinase","Activated",2,3.2100000000000001E-5]
["PLK2"," ","kinase","Activated",2,3.7700000000000002E-5]
["BAK1"," ","other","Activated",2,5.8900000000000002E-5]
["BAX"," ","transporter","Activated",2,2.5799999999999998E-4]
["Creb"," ","group","Activated",2,2.3699999999999999E-2]
["RICTOR"," ","other","Activated",2.2000000000000002,4.2900000000000001E-2]
["Map3k7"," ","kinase","Activated",2.2189999999999999,1.1E-4]
["TNF"," ","cytokine","Activated",2.3860000000000001,7.2900000000000005E-4]
["MB21D1"," ","enzyme","Activated",2.4119999999999999,1.71E-12]
["TLR7"," ","transmembrane receptor","Activated",2.415,2.26E-6]
["FZD9"," ","g-protein coupled receptor","Activated",2.4249999999999998,4.19E-10]
["TNK1"," ","kinase","Activated",2.4489999999999998,6.9399999999999998E-10]
["ARHGAP21"," ","other","Activated",2.4489999999999998,7.1299999999999999E-7]
["TLR4"," ","transmembrane receptor","Activated",2.5430000000000001,5.7000000000000002E-17]
["MYD88"," ","other","Activated",2.5779999999999998,8.3799999999999999E-4]
["TMEM173"," ","other","Activated",2.621,5.6600000000000001E-10]
["IFN alpha/beta"," ","group","Activated",2.621,1.5599999999999999E-7]
["Interferon alpha"," ","group","Activated",2.7890000000000001,1.8500000000000001E-10]
["TLR9"," ","transmembrane receptor","Activated",2.9590000000000001,3.1300000000000001E-6]
["TLR3"," ","transmembrane receptor","Activated",2.9609999999999999,1.4100000000000001E-7]
["IFNAR1"," ","transmembrane receptor","Activated",3.0910000000000002,8.98E-16]
["IFNB1"," ","cytokine","Activated",3.097,3.1999999999999999E-18]
["FADD"," ","other","Activated",3.113,7.0800000000000004E-11]
["IRF5"," ","transcription regulator","Activated",3.2650000000000001,4.6200000000000001E-15]
["MAVS"," ","other","Activated",3.302,1.4999999999999999E-14]
["TICAM1"," ","other","Activated",3.411,7.93E-11]
["DDX58"," ","enzyme","Activated",3.556,2.3399999999999999E-18]
["DOCK8"," ","other","Activated",3.8730000000000002,1.9799999999999999E-18]
["NFATC2"," ","transcription regulator","Activated",3.8730000000000002,4.55E-16]
["SASH1"," ","other","Activated",4.1230000000000002,1.56E-21]
["SAMSN1"," ","other","Activated",4.1230000000000002,8.34E-20]
["IFNG"," ","cytokine","Activated",4.2229999999999999,4.4800000000000002E-9]
["STAT1",2.3220000000000001,"transcription regulator","Activated",4.2450000000000001,3.03E-19]
["Ifnar"," ","group","Activated",4.2770000000000001,4.04E-23]
["IRF7",3.5169999999999999,"transcription regulator","Activated",4.7060000000000004,1.5699999999999999E-33]
["IRF3"," ","transcription regulator","Activated",4.9729999999999999,7.7500000000000003E-33]

{"sheet":"Cdkn1a-null","index":2,"n_rows":347,"n_cols":6,"rows_kept":347,"cut":false,"hidden":false,"merged":[]}
["Upstream Regulator","Expr Fold Change","Molecule Type","Predicted Activation State","Activation z-score","p-value of overlap"]
["TRIM24"," ","transcription regulator","Inhibited",-7.1740000000000004,9.4899999999999999E-37]
["IL10RA",2.0859999999999999,"transmembrane receptor","Inhibited",-6.867,2.14E-16]
["mir-21"," ","microrna","Inhibited",-5.9470000000000001,3.7499999999999999E-23]
["PTGER4"," ","g-protein coupled receptor","Inhibited",-5.4379999999999997,1.9900000000000001E-25]
["SOCS1",2.266,"other","Inhibited",-5.2279999999999998,3.9799999999999998E-14]
["ACKR2"," ","g-protein coupled receptor","Inhibited",-5.1959999999999997,2.95E-22]
["Irgm1",2.544,"other","Inhibited",-4.1230000000000002,1.14E-8]
["CD3"," ","complex","Inhibited",-3.7469999999999999,5.4500000000000003E-5]
["APOE",2.036,"transporter","Inhibited",-3.6890000000000001,3.9999999999999998E-6]
["SCAP"," ","other","Inhibited",-3.4950000000000001,9.16E-7]
["Nr1h"," ","group","Inhibited",-3.4,2.6399999999999998E-7]
["DNASE2"," ","enzyme","Inhibited",-3.2650000000000001,2.6300000000000001E-15]
["ATP7B"," ","transporter","Inhibited",-3.0510000000000002,5.7799999999999997E-6]
["NR3C1"," ","ligand-dependent nuclear receptor","Inhibited",-3.0139999999999998,1.7899999999999999E-4]
["NCSTN"," ","peptidase","Inhibited",-3,8.5700000000000001E-4]
["STAT3"," ","transcription regulator","Inhibited",-2.9980000000000002,9.2400000000000003E-24]
["NR1H2"," ","ligand-dependent nuclear receptor","Inhibited",-2.9870000000000001,2.26E-5]
["KDM1A"," ","enzyme","Inhibited",-2.9159999999999999,8.2799999999999992E-3]
["RPSA"," ","translation regulator","Inhibited",-2.8279999999999998,5.1199999999999998E-4]
["ZNF106"," ","other","Inhibited",-2.8279999999999998,2.46E-2]
["TGFB1"," ","growth factor","Inhibited",-2.8130000000000002,2.26E-5]
["MYT1"," ","transcription regulator","Inhibited",-2.6459999999999999,1.94E-4]
["BCL3"," ","transcription regulator","Inhibited",-2.6459999999999999,4.37E-4]
["GFI1"," ","transcription regulator","Inhibited",-2.6459999999999999,0.23599999999999999]
["SREBF2",-1.5249999999999999,"transcription regulator","Inhibited",-2.621,7.4200000000000001E-5]
["SCD"," ","enzyme","Inhibited",-2.58,2.1700000000000001E-2]
["Alpha catenin"," ","group","Inhibited",-2.5470000000000002,0.38300000000000001]
["BCL6"," ","transcription regulator","Inhibited",-2.5339999999999998,2.1599999999999999E-4]
["THRB"," ","ligand-dependent nuclear receptor","Inhibited",-2.496,1.84E-2]
["DBI"," ","other","Inhibited",-2.4489999999999998,1.68E-6]
["USP18",5.0990000000000002,"peptidase","Inhibited",-2.4329999999999998,1.2300000000000001E-4]
["SRF",-1.2589999999999999,"transcription regulator","Inhibited",-2.4329999999999998,1]
["THRA"," ","ligand-dependent nuclear receptor","Inhibited",-2.4239999999999999,4.4999999999999999E-4]
["IGF1R"," ","transmembrane receptor","Inhibited",-2.343,1]
["Ptprd"," ","phosphatase","Inhibited",-2.2360000000000002,3.5100000000000001E-3]
["GPS2"," ","transcription regulator","Inhibited",-2.2360000000000002,0.11899999999999999]
["PRDM1"," ","transcription regulator","Inhibited",-2.2360000000000002,1]
["S100A8"," ","other","Inhibited",-2.2189999999999999,2.0600000000000002E-3]
["Ciap"," ","group","Inhibited",-2.2189999999999999,3.8300000000000001E-2]
["ARNT"," ","transcription regulator","Inhibited",-2.2189999999999999,0.40600000000000003]
["TRIM21",1.968,"enzyme","Inhibited",-2.214,3.1E-4]
["ZFP36"," ","transcription regulator","Inhibited",-2.1829999999999998,0.17799999999999999]
["PRKAA2"," ","kinase","Inhibited",-2.1579999999999999,0.38100000000000001]
["CASP8"," ","peptidase","Inhibited",-2.157,9.1100000000000003E-4]
["TSC2"," ","other","Inhibited",-2.1389999999999998,9.59E-5]
["IL2RG",1.982,"transmembrane receptor","Inhibited",-2.121,3.49E-2]
["INSR"," ","kinase","Inhibited",-2.0209999999999999,0.10299999999999999]
["PTPN11"," ","phosphatase","Inhibited",-2.008,9.1500000000000001E-3]
["RNASEH2B"," ","enzyme","Inhibited",-2,1.0299999999999999E-11]
["RRM2B"," ","enzyme","Inhibited",-2,4.0599999999999998E-5]
["RPL22"," ","other","Inhibited",-2,5.3399999999999997E-4]
["mir-135"," ","microrna","Inhibited",-2,3.6800000000000001E-3]
["RXRB"," ","ligand-dependent nuclear receptor","Inhibited",-2,1.61E-2]
["IDO1"," ","enzyme","Inhibited",-2,1.61E-2]
["PTPN6",1.423,"phosphatase","Inhibited",-2,3.2399999999999998E-2]
["Brd4"," ","kinase","Inhibited",-2,0.34200000000000003]
["BACH2",-1.395,"transcription regulator","Inhibited",-2,0.41699999999999998]
["UBA7",2.0390000000000001,"enzyme"," ",-1.998,4.0599999999999998E-5]
["NOS3"," ","enzyme"," ",-1.9970000000000001,0.13400000000000001]
["TOPBP1"," ","other"," ",-1.9870000000000001,2.1800000000000001E-3]
["PLA2G2D",4.093,"enzyme"," ",-1.982,1.61E-2]
["ITGB3",-1.972,"transmembrane receptor"," ",-1.9810000000000001,9.3600000000000003E-2]
["NBEAL2"," ","other"," ",-1.98,1.61E-2]
["SOX2"," ","transcription regulator"," ",-1.9730000000000001,0.28199999999999997]
["PTPN22"," ","phosphatase"," ",-1.964,5.9799999999999999E-2]
["PTX3"," ","other"," ",-1.944,4.3800000000000002E-3]
["PSEN2"," ","peptidase"," ",-1.9350000000000001,1.5100000000000001E-3]
["mir-155"," ","microrna"," ",-1.9330000000000001,1.3600000000000001E-3]
["PSEN1"," ","peptidase"," ",-1.925,5.7000000000000002E-3]
["ABCG1"," ","transporter"," ",-1.925,0.19800000000000001]
["ERN1"," ","kinase"," ",-1.9119999999999999,0.379]
["NPC1"," ","transporter"," ",-1.901,1.6799999999999999E-4]
["TRAF2"," ","enzyme"," ",-1.89,5.8200000000000002E-2]
["FOXA2"," ","transcription regulator"," ",-1.8859999999999999,1.5800000000000002E-2]
["IL10"," ","cytokine"," ",-1.861,5.0499999999999999E-6]
["CD40",1.829,"transmembrane receptor"," ",-1.66,1.1599999999999999E-2]
["IRF9",1.831,"transcription regulator"," ",-1.633,3.4400000000000003E-5]
["NODAL"," ","growth factor"," ",-1.633,1.47E-3]
["KDM2B"," ","enzyme"," ",-1.633,9.8899999999999995E-3]
["Cyp2c44"," ","enzyme"," ",-1.5840000000000001,2.0600000000000002E-3]
["HMOX1"," ","enzyme"," ",-1.506,4.48E-2]
["DUSP1"," ","phosphatase"," ",-1.444,1.97E-3]
["ALOX5",2.8450000000000002,"enzyme"," ",-1.4,8.8599999999999998E-3]
["PPARD"," ","ligand-dependent nuclear receptor"," ",-1.36,1.8400000000000001E-3]
["TNFRSF4"," ","transmembrane receptor"," ",-1.3420000000000001,1.46E-2]
["STAT6"," ","transcription regulator"," ",-1.3,8.8699999999999996E-20]
["STAT5A"," ","transcription regulator"," ",-1.2370000000000001,1.6199999999999999E-6]
["CXCR2"," ","g-protein coupled receptor"," ",-1.1950000000000001,5.7899999999999998E-4]
["SLC4A1",-18.062000000000001,"transporter"," ",-1.1919999999999999,2.1800000000000001E-3]
["miR-155-5p (miRNAs w/seed UAAUGCU)"," ","mature microrna"," ",-1.1879999999999999,4.1700000000000001E-2]
["GPX1"," ","enzyme"," ",-1.131,2.23E-2]
["NR1H3",1.7030000000000001,"ligand-dependent nuclear receptor"," ",-1.1180000000000001,4.71E-5]
["IL1R1"," ","transmembrane receptor"," ",-1.109,1.2500000000000001E-2]
["STAT5B"," ","transcription regulator"," ",-1.105,4.1599999999999998E-2]
["TRAF3"," ","enzyme"," ",-1.093,2.0899999999999998E-2]
["CBFB"," ","transcription regulator"," ",-1.069,1.46E-4]
["CREB1"," ","transcription regulator"," ",-1.0669999999999999,1.1599999999999999E-2]
["NQO1"," ","enzyme"," ",-1.0660000000000001,1.08E-3]
["LEPR"," ","transmembrane receptor"," ",-1.0620000000000001,3.3999999999999998E-3]
["CTSE"," ","peptidase"," ",-1,1.17E-3]
["OSBPL8"," ","transporter"," ",-1,5.7600000000000004E-3]
["BRD2"," ","kinase"," ",-1,5.7600000000000004E-3]
["SCAVENGER receptor CLASS A"," ","group"," ",-1,1.61E-2]
["HIPK2"," ","kinase"," ",-1,3.2300000000000002E-2]
["CAMP"," ","other"," ",-1,3.39E-2]
["DCN"," ","other"," ",-1,4.1700000000000001E-2]
["N-cor"," ","group"," ",-0.98099999999999998,2.7700000000000001E-4]
["CREBBP"," ","transcription regulator"," ",-0.91300000000000003,6.1499999999999999E-4]
["RHO"," ","g-protein coupled receptor"," ",-0.90500000000000003,3.6800000000000001E-3]
["CD28"," ","transmembrane receptor"," ",-0.879,1.0200000000000001E-3]
["DMP1"," ","other"," ",-0.86699999999999999,3.8699999999999998E-2]
["SLC13A1"," ","transporter"," ",-0.83199999999999996,3.0800000000000001E-2]
["IL15RA"," ","transmembrane receptor"," ",-0.82,7.4200000000000001E-5]
["ACTL6A"," ","other"," ",-0.70699999999999996,2.6800000000000001E-4]
["CYP1B1"," ","enzyme"," ",-0.63200000000000001,2.0600000000000002E-3]
["CYP1A2"," ","enzyme"," ",-0.63200000000000001,2.4599999999999999E-3]
["CYP1A1"," ","enzyme"," ",-0.63200000000000001,1.55E-2]
["LYN"," ","kinase"," ",-0.57799999999999996,2.13E-4]
["CD70"," ","cytokine"," ",-0.51400000000000001,3.5100000000000001E-3]
["FUT8"," ","enzyme"," ",-0.44700000000000001,6.6899999999999998E-3]
["DICER1"," ","enzyme"," ",-0.38900000000000001,3.2599999999999997E-2]
["PPARG"," ","ligand-dependent nuclear receptor"," ",-0.37,2.66E-3]
["IL27RA"," ","transmembrane receptor"," ",-0.34200000000000003,8.5700000000000001E-4]
["MAPK1"," ","kinase"," ",-0.32,0.02]
["C5"," ","cytokine"," ",-0.23899999999999999,2.1999999999999999E-2]
["JUN"," ","transcription regulator"," ",-0.218,1.5299999999999999E-2]
["Pka"," ","complex"," ",-0.14599999999999999,1.08E-3]
["ABCA4"," ","transporter"," ",-0.13,8.3599999999999999E-5]
["IRF2"," ","transcription regulator"," ",-0.128,4.8999999999999998E-3]
["PRKCB",1.6639999999999999,"kinase"," ",-0.128,1.2200000000000001E-2]
["MMP9"," ","peptidase"," ",-0.115,1.1199999999999999E-5]
["IL4"," ","cytokine"," ",-0.08,1.67E-18]
["INSIG1",-1.7889999999999999,"other"," ",-0.04,1.39E-11]
["NHLH2"," ","other"," ",0,1.61E-2]
["SHARPIN"," ","other"," ",0,1.61E-2]
["CHADL"," ","other"," ",0,2.4799999999999999E-2]
["PTH1R"," ","g-protein coupled receptor"," ",3.7999999999999999E-2,2.7099999999999999E-2]
["MOG"," ","other"," ",0.114,4.37E-4]
["Cdc42"," ","enzyme"," ",0.13200000000000001,1.39E-8]
["RBPJ"," ","transcription regulator"," ",0.14000000000000001,3.5900000000000001E-2]
["HOXC8"," ","transcription regulator"," ",0.186,1.77E-2]
["SOCS3"," ","phosphatase"," ",0.218,4.4200000000000003E-2]
["CFTR"," ","ion channel"," ",0.28499999999999998,2.23E-2]
["RORA"," ","ligand-dependent nuclear receptor"," ",0.35499999999999998,1.8499999999999999E-2]
["ADIPOQ"," ","other"," ",0.376,9.6400000000000001E-4]
["C3AR1",2.4870000000000001,"g-protein coupled receptor"," ",0.38800000000000001,1.9E-2]
["ZBTB16"," ","transcription regulator"," ",0.435,5.3400000000000002E-10]
["IL6"," ","cytokine"," ",0.45200000000000001,4.96E-3]
["FLI1"," ","transcription regulator"," ",0.48499999999999999,5.4400000000000004E-3]
["IRAK4"," ","kinase"," ",0.56299999999999994,1.46E-4]
["RXRA"," ","ligand-dependent nuclear receptor"," ",0.59399999999999997,3.5299999999999998E-2]
["SATB1"," ","transcription regulator"," ",0.60699999999999998,8.2799999999999996E-4]
["PI3K (complex)"," ","complex"," ",0.60799999999999998,4.1700000000000001E-2]
["REL"," ","transcription regulator"," ",0.61799999999999999,7.4400000000000006E-5]
["PPARA"," ","ligand-dependent nuclear receptor"," ",0.624,2.7699999999999999E-2]
["LTBR"," ","transmembrane receptor"," ",0.63300000000000001,3.2899999999999999E-2]
["IKBKE"," ","kinase"," ",0.65300000000000002,3.0199999999999999E-9]
["TP73"," ","transcription regulator"," ",0.754,2.0299999999999999E-2]
["IFNL3"," ","cytokine"," ",0.86499999999999999,8.4799999999999997E-3]
["CD38",1.891,"enzyme"," ",0.94599999999999995,1.14E-2]
["IL5"," ","cytokine"," ",0.95099999999999996,4.8199999999999996E-3]
["CD47",1.7569999999999999,"transmembrane receptor"," ",0.97499999999999998,2.7099999999999999E-2]
["AGER"," ","transmembrane receptor"," ",0.99,1.6299999999999999E-2]
["KLF6"," ","transcription regulator"," ",1.0669999999999999,2.0600000000000002E-3]
["EBF1"," ","transcription regulator"," ",1.115,3.0599999999999998E-3]
["ABCA1"," ","transporter"," ",1.202,1.0699999999999999E-2]
["NFKBIA"," ","transcription regulator"," ",1.2110000000000001,1.9000000000000001E-5]
["SIRT6"," ","enzyme"," ",1.2130000000000001,1.6299999999999999E-2]
["KRT17"," ","other"," ",1.2649999999999999,6.9800000000000003E-5]
["MAPK9"," ","kinase"," ",1.2809999999999999,7.8700000000000005E-4]
["Traj18"," ","other"," ",1.3420000000000001,9.9099999999999991E-4]
["JINK1/2"," ","group"," ",1.387,1.5900000000000001E-3]
["CCR1",2.2519999999999998,"g-protein coupled receptor"," ",1.387,2.7E-2]
["NCOA2"," ","transcription regulator"," ",1.4890000000000001,1.6899999999999999E-7]
["IL17A"," ","cytokine"," ",1.5389999999999999,3.5799999999999998E-2]
["BCR (complex)"," ","complex"," ",1.6160000000000001,5.1700000000000001E-3]
["THBS4"," ","other"," ",1.633,1.47E-3]
["Ccl2",2.8929999999999998,"cytokine"," ",1.6539999999999999,9.6599999999999995E-4]
["LCN2"," ","transporter"," ",1.6559999999999999,3.7399999999999998E-4]
["TCR"," ","complex"," ",1.6679999999999999,3.7599999999999999E-3]
["DMD"," ","other"," ",1.698,3.7600000000000001E-2]
["PLAU"," ","peptidase"," ",1.718,4.3600000000000002E-3]
["STAT4",2.778,"transcription regulator"," ",1.8320000000000001,5.7000000000000005E-7]
["FOXO1"," ","transcription regulator"," ",1.883,0.126]
["OSM"," ","cytokine"," ",1.8919999999999999,8.5199999999999998E-2]
["IFNGR1"," ","transmembrane receptor"," ",1.9119999999999999,2.0699999999999998E-3]
["TLR5"," ","transmembrane receptor"," ",1.964,2.81E-3]
["JAK2"," ","kinase"," ",1.9690000000000001,7.0199999999999999E-2]
["OLR1"," ","transmembrane receptor"," ",1.9690000000000001,0.19800000000000001]
["Ige"," ","complex"," ",1.9690000000000001,0.215]
["SCARB1"," ","transporter"," ",1.9770000000000001,7.0199999999999999E-2]
["CARM1",-1.4810000000000001,"transcription regulator"," ",1.98,1.1900000000000001E-2]
["PEX5L"," ","ion channel"," ",1.98,1.61E-2]
["SAA1"," ","transporter"," ",1.982,1.9000000000000001E-4]
["ACACB"," ","enzyme"," ",1.982,2.7099999999999999E-2]
["TNFSF15"," ","cytokine"," ",1.982,5.9799999999999999E-2]
["IL23A"," ","cytokine"," ",1.982,8.1500000000000003E-2]
["CD5L"," ","transmembrane receptor","Activated",2,4.0599999999999998E-5]
["TNFRSF17"," ","transmembrane receptor","Activated",2,1.9000000000000001E-4]
["NSD2"," ","enzyme","Activated",2,5.3399999999999997E-4]
["TSLP"," ","cytokine","Activated",2,2.1800000000000001E-3]
["MAP3K5"," ","kinase","Activated",2,2.1800000000000001E-3]
["ZBP1",4.7069999999999999,"other","Activated",2,8.4799999999999997E-3]
["CEACAM1"," ","transporter","Activated",2,8.4799999999999997E-3]
["MED13"," ","transcription regulator","Activated",2,9.1500000000000001E-3]
["IRAK3"," ","kinase","Activated",2,2.7099999999999999E-2]
["RGS1",2.915,"other","Activated",2,2.7099999999999999E-2]
["ZC3H14"," ","other","Activated",2,4.1700000000000001E-2]
["PAX5"," ","transcription regulator","Activated",2,5.9799999999999999E-2]
["PTGES"," ","enzyme","Activated",2,5.9799999999999999E-2]
["IL17RA"," ","transmembrane receptor","Activated",2,0.13400000000000001]
["HES3"," ","other","Activated",2,0.45300000000000001]
["PIK3R1"," ","kinase","Activated",2.0179999999999998,0.16700000000000001]
["PTGER2"," ","g-protein coupled receptor","Activated",2.121,0.39300000000000002]
["IL15"," ","cytokine","Activated",2.1360000000000001,4.2599999999999999E-3]
["IL11RA"," ","transmembrane receptor","Activated",2.157,2.05E-5]
["Hbb-b1"," ","transporter","Activated",2.1589999999999998,3.3700000000000001E-9]
["Klra7 (includes others)",4.8970000000000002,"transmembrane receptor","Activated",2.1840000000000002,3.1599999999999998E-6]
["VIPR1"," ","g-protein coupled receptor","Activated",2.2000000000000002,1.8099999999999999E-5]
["CHEK2"," ","kinase","Activated",2.2000000000000002,1.8099999999999999E-5]
["INSIG2"," ","other","Activated",2.2000000000000002,3.5100000000000001E-3]
["NR1I3"," ","ligand-dependent nuclear receptor","Activated",2.2029999999999998,8.0299999999999996E-2]
["VEGFA"," ","growth factor","Activated",2.2090000000000001,8.2799999999999992E-3]
["CSF1",1.4119999999999999,"cytokine","Activated",2.2130000000000001,5.2400000000000002E-2]
["PTPRC"," ","phosphatase","Activated",2.2189999999999999,1.8799999999999999E-4]
["SYK"," ","kinase","Activated",2.2189999999999999,1.47E-3]
["IFI16",6.7549999999999999,"transcription regulator","Activated",2.2189999999999999,2.4099999999999998E-3]
["FDFT1"," ","enzyme","Activated",2.2189999999999999,1.15E-2]
["CXCL3"," ","cytokine","Activated",2.2240000000000002,1.5900000000000001E-3]
["IgG"," ","complex","Activated",2.2360000000000002,3.23E-6]
["MAPKAP1"," ","other","Activated",2.2360000000000002,5.9200000000000002E-5]
["CYP51A1",-1.5049999999999999,"enzyme","Activated",2.2360000000000002,2.4099999999999998E-3]
["LGALS3"," ","other","Activated",2.2360000000000002,0.11899999999999999]
["RARA"," ","ligand-dependent nuclear receptor","Activated",2.2360000000000002,0.35399999999999998]
["NOD2"," ","other","Activated",2.3199999999999998,1.0999999999999999E-2]
["IL2"," ","cytokine","Activated",2.3239999999999998,4.6400000000000003E-5]
["ID3"," ","transcription regulator","Activated",2.3330000000000002,4.1899999999999999E-4]
["STAT2",2.8759999999999999,"transcription regulator","Activated",2.347,3.7100000000000001E-10]
["LEP"," ","growth factor","Activated",2.351,1.6900000000000001E-3]
["MIF"," ","cytokine","Activated",2.3730000000000002,7.8299999999999995E-2]
["TNFRSF1A"," ","transmembrane receptor","Activated",2.3730000000000002,0.111]
["PTGS2"," ","enzyme","Activated",2.4119999999999999,0.33900000000000002]
["KDM6B"," ","enzyme","Activated",2.4249999999999998,1.79E-7]
["F2RL1"," ","g-protein coupled receptor","Activated",2.4279999999999999,7.9399999999999991E-3]
["IFNA4"," ","cytokine","Activated",2.4329999999999998,8.3599999999999999E-5]
["FAS",4.3810000000000002,"transmembrane receptor","Activated",2.4329999999999998,1.1900000000000001E-2]
["Tlr"," ","group","Activated",2.4329999999999998,3.8699999999999998E-2]
["CXCL2"," ","cytokine","Activated",2.4340000000000002,4.4099999999999999E-4]
["TNNI3"," ","transporter","Activated",2.4489999999999998,5.0699999999999997E-6]
["ZBTB33"," ","other","Activated",2.4489999999999998,6.2600000000000002E-6]
["MARK2"," ","kinase","Activated",2.4489999999999998,3.3599999999999998E-2]
["NLRP3"," ","other","Activated",2.484,1.6500000000000001E-2]
["MAPK14"," ","kinase","Activated",2.5209999999999999,1.4899999999999999E-4]
["ID2"," ","transcription regulator","Activated",2.5299999999999998,4.1899999999999999E-4]
["CEBPB"," ","transcription regulator","Activated",2.5369999999999999,0.21199999999999999]
["NFKB1"," ","transcription regulator","Activated",2.5590000000000002,4.2400000000000001E-6]
["IRF8",1.7869999999999999,"transcription regulator","Activated",2.5979999999999999,2.0899999999999999E-6]
["ERK1/2"," ","group","Activated",2.621,0.28599999999999998]
["PROCR",1.5089999999999999,"other","Activated",2.6230000000000002,6.3900000000000004E-7]
["CRKL"," ","kinase","Activated",2.63,7.4200000000000001E-5]
["SQSTM1"," ","transcription regulator","Activated",2.6459999999999999,2.8899999999999999E-2]
["BTNL2"," ","transmembrane receptor","Activated",2.6459999999999999,0.39200000000000002]
["CSF2"," ","cytokine","Activated",2.6629999999999998,2.5399999999999999E-2]
["IL12A"," ","cytokine","Activated",2.7290000000000001,1.2999999999999999E-4]
["IL18"," ","cytokine","Activated",2.75,1.2500000000000001E-2]
["C5AR1",2.2599999999999998,"g-protein coupled receptor","Activated",2.7589999999999999,1.9099999999999999E-2]
["IFIH1",2.5489999999999999,"enzyme","Activated",2.76,4.8899999999999998E-6]
["Fcer1"," ","complex","Activated",2.7770000000000001,9.1100000000000003E-4]
["SPI1",2.2400000000000002,"transcription regulator","Activated",2.7789999999999999,7.4000000000000003E-3]
["MAPKAPK2"," ","kinase","Activated",2.7890000000000001,1.66E-2]
["MGEA5"," ","enzyme","Activated",2.7949999999999999,1.95E-12]
["TBK1"," ","kinase","Activated",2.8039999999999998,1.13E-8]
["BAK1"," ","other","Activated",2.8039999999999998,1.5299999999999999E-3]
["TNK1"," ","kinase","Activated",2.8279999999999998,6.2899999999999999E-6]
["LAMA5"," ","other","Activated",2.8279999999999998,1.17E-5]
["TFEB"," ","transcription regulator","Activated",2.8279999999999998,1.17E-5]
["LIF",1.9710000000000001,"cytokine","Activated",2.8279999999999998,0.16900000000000001]
["PLK4"," ","kinase","Activated",2.887,1.2599999999999999E-7]
["PLK2",1.345,"kinase","Activated",2.887,2.17E-7]
["EGR1"," ","transcription regulator","Activated",2.895,4.2399999999999999E-7]
["CCR2"," ","g-protein coupled receptor","Activated",2.895,1.28E-6]
["TLR2"," ","transmembrane receptor","Activated",2.9239999999999999,2.7E-4]
["MB21D1"," ","enzyme","Activated",2.9580000000000002,5.4800000000000001E-11]
["CCR5",2.5649999999999999,"g-protein coupled receptor","Activated",2.9660000000000002,8.5700000000000001E-4]
["POR"," ","enzyme","Activated",2.9740000000000002,9.0799999999999995E-3]
["mir-223"," ","microrna","Activated",2.9820000000000002,1.4300000000000001E-4]
["PPIF"," ","enzyme","Activated",2.9849999999999999,4.2899999999999996E-6]
["TRPV4"," ","ion channel","Activated",2.9849999999999999,2.4700000000000001E-5]
["BID"," ","other","Activated",3,4.1600000000000002E-7]
["MET"," ","kinase","Activated",3,2.3400000000000001E-2]
["ETS1"," ","transcription regulator","Activated",3.0270000000000001,3.77E-8]
["IL12 (complex)"," ","complex","Activated",3.032,3.4100000000000002E-15]
["IL12B"," ","cytokine","Activated",3.0539999999999998,1.2800000000000001E-7]
["BAX",2.5739999999999998,"transporter","Activated",3.0649999999999999,1.45E-5]
["RELA"," ","transcription regulator","Activated",3.1240000000000001,5.3900000000000005E-7]
["PTPRJ"," ","phosphatase","Activated",3.1619999999999999,2.4599999999999999E-3]
["IKBKG"," ","kinase","Activated",3.1669999999999998,1.1599999999999999E-6]
["ITK",3.6669999999999998,"kinase","Activated",3.1869999999999998,4.7199999999999997E-14]
["Hbb-b2"," ","other","Activated",3.2069999999999999,2.5200000000000001E-8]
["IRF1",1.5009999999999999,"transcription regulator","Activated",3.2360000000000002,1.32E-3]
["FZD9"," ","g-protein coupled receptor","Activated",3.2829999999999999,2.3700000000000001E-10]
["SPIB"," ","transcription regulator","Activated",3.3050000000000002,3.9400000000000002E-5]
["Map3k7"," ","kinase","Activated",3.3570000000000002,1.13E-8]
["RETNLB"," ","other","Activated",3.3570000000000002,6.5099999999999999E-4]
["NOS2"," ","enzyme","Activated",3.4340000000000002,1.08E-9]
["P38 MAPK"," ","group","Activated",3.44,1.49E-3]
["CD44"," ","other","Activated",3.456,4.0200000000000001E-4]
["IL13"," ","cytokine","Activated",3.6309999999999998,5.7299999999999997E-5]
["IL1B"," ","cytokine","Activated",3.657,3.1099999999999999E-3]
["TP53"," ","transcription regulator","Activated",3.7040000000000002,3.6800000000000002E-10]
["ARHGAP21"," ","other","Activated",3.742,3.4800000000000001E-6]
["RIPK2"," ","kinase","Activated",3.766,1.75E-4]
["TNFSF12"," ","cytokine","Activated",3.7839999999999998,1E-3]
["TLR7",2.78,"transmembrane receptor","Activated",3.79,4.88E-8]
["NFkB (complex)"," ","complex","Activated",3.8170000000000002,4.3899999999999999E-9]
["TMEM173"," ","other","Activated",3.843,3.8199999999999998E-8]
["PARP1"," ","enzyme","Activated",3.9319999999999999,7.4000000000000001E-9]
["FADD"," ","other","Activated",3.96,1.15E-9]
["Interferon alpha"," ","group","Activated",4.04,1.3499999999999999E-14]
["CDKN2A"," ","transcription regulator","Activated",4.1980000000000004,6.3299999999999994E-5]
["CHUK"," ","kinase","Activated",4.2060000000000004,1.4799999999999999E-4]
["IRF5",2.036,"transcription regulator","Activated",4.2759999999999998,3.2300000000000001E-11]
["TNF"," ","cytokine","Activated",4.3659999999999997,4.2200000000000003E-6]
["MAVS"," ","other","Activated",4.41,2.6200000000000001E-12]
["TLR9"," ","transmembrane receptor","Activated",4.5140000000000002,9.1199999999999995E-10]
["PLA2G10"," ","enzyme","Activated",4.6580000000000004,2.5299999999999999E-11]
["DDX58",2.032,"enzyme","Activated",4.6820000000000004,1.12E-18]
["IKBKB"," ","kinase","Activated",4.8310000000000004,3.1199999999999999E-4]
["NFATC2"," ","transcription regulator","Activated",4.8869999999999996,8.3600000000000007E-12]
["IFN alpha/beta"," ","group","Activated",4.9409999999999998,8.83E-14]
["DOCK8"," ","other","Activated",5.1959999999999997,7.6699999999999996E-13]
["IFNB1"," ","cytokine","Activated",5.218,9.8799999999999997E-29]
["IFNAR1"," ","transmembrane receptor","Activated",5.2469999999999999,4.3199999999999998E-26]
["SASH1"," ","other","Activated",5.2919999999999998,2.2899999999999998E-13]
["TLR3",1.5620000000000001,"transmembrane receptor","Activated",5.4480000000000004,1.03E-15]
["SAMSN1",2.6389999999999998,"other","Activated",5.5679999999999996,4.39E-13]
["MYD88",1.2509999999999999,"other","Activated",5.7140000000000004,1.13E-9]
["TLR4"," ","transmembrane receptor","Activated",5.774,9.1899999999999999E-17]
["TICAM1"," ","other","Activated",6.2569999999999997,4.3599999999999999E-18]
["IRF7",6.3449999999999998,"transcription regulator","Activated",6.5049999999999999,4.2399999999999998E-35]
["STAT1",3.0979999999999999,"transcription regulator","Activated",7.2569999999999997,4.43E-35]
["IRF3"," ","transcription regulator","Activated",7.3760000000000003,5.1599999999999995E-47]
["Ifnar"," ","group","Activated",7.4,1.2700000000000001E-45]
["IFNG"," ","cytokine","Activated",9.7840000000000007,2.1400000000000001E-27]
[]
["adapted from QIAGEN IPA"]