Control of Heterologous Simian Immunodeficiency Virus SIV_smE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques

Supplemental material

• Supplemental file 1 -

  Fig. S1 (Phenotypic analysis of PBMCs.)

  Fig. S2 (Induction of V2 antibody responses.)

  Fig. S3 (Linear peptide response analysis of plasma bAb.)

  Fig. S4 (Durability of vaccine-induced immune responses.)

  Fig. S5 (SIV_smE660 acquisition in TRIM-5α rhesus macaques.)

  Fig. S6 (Genetic analysis of T/F Env sequences.)

  Fig. S7 (Virus load measurements of SIV_smE660-infected animals.)

  Fig. S8 (Anamnestic SIV-specific T cell responses and association of cytotoxic SIV-specific effector memory T cells with control of viremia.)

  Table S1 (Macaque information.)

  Table S2 (Parameters measured by serum serology.)

  Table S3 (Association of humoral responses with virus acquisition and control of viremia.)

  Table S4 (Association of cellular immune responses and control of viremia.)

  PDF, 2.2M