{"text_format":"2","workbook":"xlsx","n_sheets":4,"sheets":["allele phasing summary","allele phasing details","H2 accessions","H1 accessions"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"allele phasing summary","index":0,"n_rows":36,"n_cols":10,"rows_kept":36,"cut":false,"hidden":false,"merged":[[0,0,0,6],[1,8,1,9],[35,0,35,7]]}
["Supplementary Table S4: Allele comparison of 30 phased CDS between Trichoplax sp. H2 and Trichoplax adhaerens"]
[{"$nulls":8},"Mean RNA-seq read coverage"]
["Gene\n(best SwissProt hit)","description","CDS length\n(bp)","SNPs","phased blocks","different alleles","shared alleles","substitutions btw closest alleles","H2","H1"]
["tubb4b","Beta Tubulin",1344,6,1,4,0,1,12936,44371]
["Trypsin Ovochymase","Serine Protease",1224,30,1,3,"2x1","-",15723,40861]
["slc25a43","Solute carrier family 25",1002,3,1,3,"2x1","-",15592,31558]
["RPS25","40S Ribosomal protein S25",330,1,1,2,"3x1","-",9382,21437]
["RPS15a","40S ribosomal protein S15a",393,2,1,2,"2x2","-",7381,18471]
["RpLP1","60S acidic ribosomal protein P1",333,1,1,2,"3x1","-",6450,13222]
["Pax6","paired box protein",1629,19,1,3,"2x1","-",562,1223]
["Irx6","Iroquois-class homeodomain",1161,9,2,4,0,1,1202,3034]
["FoxO","Forkhead Box",1776,14,1,2,"2x2","-",44,122]
["HHEX","Homeodomain NK class",711,9,1,3,"2x1","-",87,147]
["Cathepsin L","Papain family cysteine protease",978,4,2,3,"2x1","-",4898,14682]
["Cathepsin B","Thiol protease",1002,1,1,2,"3x1","-",5342,13038]
["h1f0","Histone H1.0",573,4,1,2,"3x1","-",1153,2774]
["BDS1","Alkyl/aryl-sulfatase",2094,20,2,3,"2x1","-",2585,11268]
["ANPEP","Aminopeptidase N",2976,28,3,4,0,3,3347,6630]
["smad6","Mothers against decapentaplegic homolog 6",1239,8,2,3,"2x1","-",94,294]
["Bmp7","TGF beta",1134,15,1,4,0,1,36,111]
["Tropomyosin","Interaction with actin",738,5,1,2,"2x2","-",260,750]
["Calmodulin","calcium-binding",474,1,1,2,"2x2","-",35,100]
["PRKAG2","AMP-activated protein kinase subunit gamma-2",1287,12,1,2,"2x2","-",90,206]
["DBX","Homeodomain NK class",855,8,2,4,0,1,41,228]
["Nkx-6.2","Homeodomain NK class",651,9,1,3,"2x1","-",9,23]
["PFY1","Profilin",387,5,1,2,"2x2","-",98,137]
["Myc-1","Transcriptional regulator Myc-1",966,5,1,2,"2x2","-",808,4725]
["Aldoc","Fructose-bisphosphate aldolase C",1086,11,1,4,0,1,1533,2732]
["Sox2","Transcription factor SOX-2",948,6,1,2,"2x2","-",188,668]
["PPIB","Peptidyl-prolyl cis-trans isomerase B",552,7,1,3,"2x1","-",1232,2054]
["RPII15","DNA-directed RNA polymerase II subunit RPB9",390,2,1,2,"2x2","-",156,363]
["Snapin","SNARE-associated protein Snapin",345,3,1,2,"2x2","-",184,297]
["Streptavidin-V1",null,576,6,1,2,"2x2","-",2144,3756]
[]
["SUM",null,29154,254,37,null,null,8]
["9x one allel shared, heterozygous in both haplotypes = 30%\n4x one allele shared, homozygous in one haplotype = 13.33%\n11x both alleles shared, heterozygous in both haplotypes = 36.66%\nat least one allele shared = 80%\n6x no allele shared = 20%"]

{"sheet":"allele phasing details","index":1,"n_rows":281,"n_cols":32,"rows_kept":281,"cut":false,"hidden":false,"merged":[[0,0,0,4]]}
["Supplementary Table S4: Details of the allele comparison"]
[]
["NOTE: shown are the SNP positions between the alleles of Trichoplax adhaerens (H1) and Trichoplax sp. H2. A continous color denotes a single phased block. Identical alleles are marked with either * or #. Genomic location is given below and above the respective alleles of the two lineages. The accessions for the de-novo assembled transcripts (in one case genomic prediction), from which the CDS are derived, are given in the next two tables sheets."]
[]
["Gene/Alleles","CDS length","SNPs"]
[]
["tubb4b","1344bp"]
["scaffold_2",null,69,540,870,1047,1053,1206]
["H1",null,"T","C","A","T","C","T"]
["H1",null,"G","T","T","G","T","T"]
[]
["H2",null,"T","T","T","G","T","T"]
["H2",null,"T","C","A","T","C","A"]
["scaffold_92"]
[]
["Trypsin Ovochymase","1224bp"]
["scaffold_4",null,54,146,176,182,190,287,446,460,465,487,488,489,504,505,506,578,581,620,621,624,665,667,674,676,722,908,919,931,1213,1215]
["H1",null,"T","A","T","A","T","G","T","T","G","G","C","A","A","G","G","G","A","C","C","C","G","A","A","G","C","A","A","G","C","G"]
["H1","*","C","G","C","G","G","C","T","T","C","G","C","A","G","A","C","A","C","G","A","T","C","T","G","A","T","C","G","A","A","C"]
[]
["H2","*","C","G","C","G","G","C","T","T","C","G","C","A","G","A","C","A","C","G","A","T","C","T","G","A","T","C","G","A","A","C"]
["H2",null,"T","A","T","A","T","G","C","G","G","T","T","T","G","G","C","G","G","C","C","C","G","A","A","G","T","C","G","G","C","G"]
["scaffold_25"]
[]
["slc25a43","1002bp"]
["scaffold_5",null,591,792,883]
["H1",null,"G","C","G"]
["H1","*","A","T","A"]
[]
["H2","*","A","T","A"]
["H2",null,"G","C","A"]
["scaffold_187"]
[]
["RPS25","330bp"]
["scaffold_1",null,237]
["H1",null,"A"]
["H1","*","T"]
[]
["H2","*","T"]
["H2","*","T"]
["scaffold_68"]
[]
["Rps15a","393bp"]
["scaffold_46",null,93,231]
["H1","#","T","C"]
["H1","*","A","T"]
[]
["H2","*","A","T"]
["H2","#","T","C"]
["scaffold_205"]
[]
["RpLP1","333bp"]
["scaffold_7",null,12]
["H1",null,"G"]
["H1","*","A"]
[]
["H2","*","A"]
["H2","*","A"]
["scaffold_300"]
[]
[]
["Pax6","1629bp"]
["scaffold_10",null,18,222,510,545,612,699,852,958,961,968,969,996,1001,1198,1261,1275,1303,1395,1410]
["H1",null,"T","T","A","T","C","C","T","C","C","G","C","T","C","G","A","C","A","G","A"]
["H1","*","C","A","G","C","T","T","C","T","A","A","T","C","T","A","G","T","C","A","T"]
[]
["H2","*","C","A","G","C","T","T","C","T","A","A","T","C","T","A","G","T","C","A","T"]
["H2",null,"T","T","A","T","C","C","T","C","A","G","C","T","C","G","A","C","A","G","A"]
["scaffold_8"]
[]
["Irx6","1161bp"]
["scaffold_4",null,68,129,157,600,825,853,963,1017,1043]
["H1",null,"C","A","T","T","A","T","A","C","T"]
["H1",null,"C","G","C","A","G","A","G","A","G"]
[]
["H2",null,"C","G","C","A","G","A","A","A","G"]
["H2",null,"G","A","T","T","A","T","A","C","T"]
["scaffold_44"]
[]
["FoxO","1776bp"]
["scaffold_5",null,231,273,609,738,788,832,929,936,974,1176,1179,1285,1440,1738]
["H1","#","T","T","G","G","G","A","A","A","G","C","G","G","G","G"]
["H1","*","G","C","A","A","A","T","G","C","A","T","A","T","A","A"]
[]
["H2","*","G","C","A","A","A","T","G","C","A","T","A","T","A","A"]
["H2","#","T","T","G","G","G","A","A","A","G","C","G","G","G","G"]
["scaffold_6"]
[]
["Hhex","711bp"]
["scaffold_17",null,138,246,262,273,331,419,422,618,621]
["H1",null,"G","T","C","G","G","T","G","G","C"]
["H1","*","G","C","T","A","A","T","A","A","T"]
[]
["H2","*","G","C","T","A","A","T","A","A","T"]
["H2",null,"A","T","C","G","G","G","G","G","C"]
["scaffold_37"]
[]
["Cathepsin L","978bp"]
["scaffold_3",null,207,280,825,932]
["H1",null,"T","G","G","A"]
["H1","*","C","T","A","G"]
[]
["H2","*","C","T","A","G"]
["H2",null,"C","G","G","A"]
["scaffold_9"]
[]
["H1f0","573bp"]
["scaffold_2",null,147,264,378,450]
["H1","*","C","T","G","C"]
["H1","*","C","T","G","C"]
[]
["H2","*","C","T","G","C"]
["H2",null,"T","G","A","T"]
["scaffold_14"]
[]
["Cathepsin B","1002bp"]
["scaffold_7",null,462]
["H1",null,"A"]
["H1","*","T"]
[]
["H2","*","T"]
["H2","*","T"]
["scaffold_22"]
[]
["BDS1","2094bp"]
["scaffold_4",null,147,148,160,216,330,423,432,725,1032,1188,1339,1476,1477,1682,1719,1742,1928,2039,2040,2068]
["H1",null,"C","T","A","G","C","T","G","G","T","A","G","A","G","G","G","C","T","C","A","A"]
["H1","*","T","A","G","G","T","C","T","C","C","A","T","C","C","A","T","T","C","C","A","A"]
[]
["H2","*","T","A","G","G","T","C","T","C","C","A","T","C","C","A","T","T","C","C","A","A"]
["H2",null,"C","T","A","A","C","T","G","C","T","G","G","C","G","G","G","C","C","G","C","G"]
["scaffold_90"]
[]
["ANPEP","2976bp"]
["scaffold_1",null,170,180,271,293,327,396,474,890,997,1050,1065,1089,1119,1120,1301,1601,1671,1699,1897,2019,2166,2181,2215,2307,2571,2686,2697,2958]
["H1",null,"G","G","C","T","A","T","C","A","G","T","A","T","G","T","G","A","A","A","G","T","T","C","A","T","A","A","T","C"]
["H1",null,"C","A","T","C","T","A","T","A","A","C","T","C","A","A","G","T","C","G","A","C","C","T","G","C","A","G","A","C"]
[]
["H2",null,"C","A","T","C","T","A","T","A","G","C","T","C","A","A","G","T","C","G","A","C","C","T","G","C","G","G","A","T"]
["H2",null,"G","G","C","T","A","T","C","T","G","T","A","T","G","T","T","T","A","A","G","T","T","C","A","T","A","A","T","C"]
["scaffold_171"]
[]
[]
["smad6","1239bp"]
["scaffold_1",null,102,177,211,243,476,529,882,1092]
["H1",null,"T","A","G","C","C","A","C","A"]
["H1","*","C","T","A","A","T","G","G","G"]
[]
["H2","*","C","T","A","A","T","G","G","G"]
["H2",null,"T","A","A","A","C","A","C","A"]
["scaffold_4"]
[]
[]
["Bmp7","1134bp"]
["scaffold_7",null,47,150,400,457,458,544,577,616,643,652,756,779,802,1043,1059]
["H1",null,"T","C","A","A","A","T","A","A","C","G","A","A","A","C","T"]
["H1",null,"C","T","A","T","C","C","C","G","A","G","G","G","G","G","C"]
[]
["H2",null,"C","T","A","T","C","C","C","G","A","G","G","G","G","C","C"]
["H2",null,"T","C","G","A","A","C","C","A","C","A","A","A","A","C","T"]
["scaffold_22"]
[]
["Tropomyosin","738bp"]
["scaffold_1",null,89,195,223,504,649]
["H1","#","C","G","A","G","G"]
["H1","*","T","A","G","A","A"]
[]
["H2","*","T","A","G","A","A"]
["H2","#","C","G","A","G","G"]
["scaffold_20"]
[]
["Calmodulin","474bp"]
["scaffold_4",null,47]
["H1","#","C"]
["H1","*","T"]
[]
["H2","*","T"]
["H2","#","C"]
["scaffold_126"]
[]
["PRKAG","1287bp"]
["scaffold_3",null,222,257,549,597,723,775,837,1063,1099,1163,1212,1283]
["H1","#","G","A","A","T","T","G","T","T","G","G","C","T"]
["H1","*","A","G","G","A","C","A","C","C","T","A","A","A"]
[]
["H2","*","A","G","G","A","C","A","C","C","T","A","A","A"]
["H2","#","G","A","A","T","T","G","T","T","G","G","C","T"]
["scaffold_13"]
[]
[]
["DBX","855bp"]
["scaffold_1",null,100,245,322,323,343,388,690,832]
["H1",null,"A","G","G","T","A","G","A","A"]
["H1",null,"G","A","A","C","A","A","G","G"]
[]
["H2",null,"G","A","A","C","C","A","G","G"]
["H2",null,"G","G","A","T","A","G","A","A"]
["scaffold_47"]
[]
["NK6","651bp"]
["scaffold_17",null,52,69,188,226,281,504,520,530,635]
["H1",null,"G","C","T","T","G","C","C","G","G"]
["H1","*","A","C","T","C","A","T","C","A","G"]
[]
["H2","*","A","C","T","C","A","T","C","A","G"]
["H2",null,"A","T","C","T","G","C","G","A","A"]
["scaffold_37"]
[]
["PFY1","387bp"]
["scaffold_1",null,12,18,214,218,355]
["H1","#","C","T","T","C","A"]
["H1","*","A","G","G","T","G"]
[]
["H2","*","A","G","G","T","G"]
["H2","#","C","T","T","C","A"]
["scaffold_176"]
[]
[]
["Myc-1","966bp"]
["scaffold_7",null,19,285,289,474,786]
["H1","#","G","T","C","G","A"]
["H1","*","A","C","T","A","G"]
[]
["H2","*","A","C","T","A","G"]
["H2","#","G","T","C","G","A"]
["scaffold_10"]
[]
["Aldoc","1086bp"]
["scaffold_15",null,114,198,199,201,206,255,261,267,525,955,1071]
["H1",null,"C","G","C","T","G","C","A","A","C","A","T"]
["H1",null,"A","T","A","G","A","C","A","A","T","G","C"]
[]
["H2",null,"A","T","A","G","A","C","A","A","T","G","T"]
["H2",null,"C","G","C","T","G","T","T","G","C","A","T"]
["scaffold_241"]
[]
["SOX2","948bp"]
["scaffold_4",null,27,288,336,372,702,837]
["H1","#","G","G","T","G","C","C"]
["H1","*","C","A","C","A","T","T"]
[]
["H2","*","C","A","C","A","T","T"]
["H2","#","G","G","T","G","C","C"]
["scaffold_11"]
[]
["PPIB","552bp"]
["scaffold_3",null,122,246,281,333,369,480,482]
["H1",null,"G","T","A","C","G","T","A"]
["H1","*","A","C","G","C","C","C","G"]
[]
["H2","*","A","C","G","C","C","C","G"]
["H2",null,"A","T","A","T","G","C","G"]
["scaffold_94"]
[]
["RPII15","390bp"]
["scaffold_1",null,132,267]
["H1","#","A","C"]
["H1","*","G","T"]
[]
["H2","*","G","T"]
["H2","#","A","C"]
["scaffold_106"]
[]
["Snapin","345bp"]
["scaffold_2",null,153,221,244]
["H1","#","G","A","A"]
["H1","*","A","G","G"]
[]
["H2","*","A","G","G"]
["H2","#","G","A","A"]
["scaffold_32"]
[]
[]
["Streptavidin V1","576bp",88,147,178,249,285,397]
["scaffold_4"]
["H1","#","A","T","C","T","T","G"]
["H1","*","G","C","T","A","C","A"]
[]
["H2","*","G","C","T","A","C","A"]
["H2","#","A","T","C","T","T","G"]
["scaffold_29"]

{"sheet":"H2 accessions","index":2,"n_rows":35,"n_cols":4,"rows_kept":35,"cut":false,"hidden":false,"merged":[[0,0,0,2]]}
["Supplementary Table S4: Trichoplax sp. H2 accessions of CDS"]
[]
[]
[]
["CDS derived from","Transcriptome/genome accession","transcript name/locus_tag","product name"]
["transcriptome","GFSF00000000","TR22588_c0_g2_i1","tubb4b"]
["transcriptome","GFSF00000000","TR8434_c0_g1_i1","Trypsin Ovochymase"]
["transcriptome","GFSF00000000","TR6678_c0_g1_i1","slc25a43"]
["transcriptome","GFSF00000000","TR6179_c0_g1_i1","RPS25"]
["transcriptome","GFSF00000000","TR7997_c0_g1_i1","RPS15a"]
["transcriptome","GFSF00000000","TR17859_c0_g1_i1","RpLP1"]
["transcriptome","GFSF00000000","TR899_c1_g1_i1","Pax6"]
["transcriptome","GFSF00000000","TR10434_c0_g1_i1","Irx6"]
["transcriptome","GFSF00000000","TR16162_c1_g1_i1","FoxO"]
["transcriptome","GFSF00000000","TR6747_c1_g1_i1","HHEX"]
["transcriptome","GFSF00000000","TR12137_c0_g1_i1","Cathepsin L"]
["transcriptome","GFSF00000000","TR14537_c0_g1_i1","Cathepsin B"]
["transcriptome","GFSF00000000","TR15630_c0_g1_i1","h1f0"]
["transcriptome","GFSF00000000","TR5757_c0_g1_i1","BDS1"]
["transcriptome","GFSF00000000","TR11718_c0_g1_i1","ANPEP"]
["transcriptome","GFSF00000000","TR17709_c0_g1_i2","smad6"]
["transcriptome","GFSF00000000","TR53_c0_g1_i3","Bmp7"]
["transcriptome","GFSF00000000","TR13356_c0_g1_i1","Tropomyosin"]
["transcriptome","GFSF00000000","TR15836_c0_g1_i2","Calmodulin"]
["transcriptome","GFSF00000000","TR964_c0_g1_i4","PRKAG2"]
["transcriptome","GFSF00000000","TR14054_c0_g1_i1","DBX"]
["genome","NOWV00000000","TrispH2_005000","Nkx-6.2"]
["transcriptome","GFSF00000000","TR14613_c0_g1_i1","PFY1"]
["transcriptome","GFSF00000000","TR19201_c0_g1_i1","Myc-1"]
["transcriptome","GFSF00000000","TR16218_c0_g1_i1","Aldoc"]
["transcriptome","GFSF00000000","TR15588_c0_g1_i1","Sox2"]
["transcriptome","GFSF00000000","TR22600_c0_g1_i1","PPIB"]
["transcriptome","GFSF00000000","TR11867_c0_g1_i2","RPII15"]
["transcriptome","GFSF00000000","TR13389_c1_g1_i2","Snapin"]
["transcriptome","GFSF00000000","TR2337_c0_g1_i1","Streptavidin-V1"]

{"sheet":"H1 accessions","index":3,"n_rows":34,"n_cols":4,"rows_kept":34,"cut":false,"hidden":false,"merged":[[0,0,0,3]]}
["Supplementary Table S4: Trichoplax adhaerens accessions of CDS"]
[]
[]
["CDS derived from","Transcriptome/genome accession","transcript name","product name"]
["transcriptome","GFSG00000000","TR9225_c0_g1_i1","tubb4b"]
["transcriptome","GFSG00000000","TR12993_c0_g1_i1","Trypsin Ovochymase"]
["transcriptome","GFSG00000000","TR13655_c0_g1_i1","slc25a43"]
["transcriptome","GFSG00000000","TR14072_c0_g1_i1","RPS25"]
["transcriptome","GFSG00000000","TR24091_c0_g1_i1","RPS15a"]
["transcriptome","GFSG00000000","TR19669_c0_g1_i1","RpLP1"]
["transcriptome","GFSG00000000","TR22999_c0_g1_i1","Pax6"]
["transcriptome","GFSG00000000","TR17107_c0_g1_i1","Irx6"]
["transcriptome","GFSG00000000","TR12986_c1_g1_i1","FoxO"]
["transcriptome","GFSG00000000","TR1903_c0_g1_i1","HHEX"]
["transcriptome","GFSG00000000","TR19405_c0_g1_i1","Cathepsin L"]
["transcriptome","GFSG00000000","TR29835_c0_g1_i1","Cathepsin B"]
["transcriptome","GFSG00000000","TR11171_c0_g1_i1","h1f0"]
["transcriptome","GFSG00000000","TR3770_c0_g1_i1","BDS1"]
["transcriptome","GFSG00000000","TR5823_c0_g1_i1","ANPEP"]
["transcriptome","GFSG00000000","TR536_c0_g1_i1","smad6"]
["transcriptome","GFSG00000000","TR10859_c0_g1_i2","Bmp7"]
["transcriptome","GFSG00000000","TR16188_c0_g1_i1","Tropomyosin"]
["transcriptome","GFSG00000000","TR2602_c0_g1_i2","Calmodulin"]
["transcriptome","GFSG00000000","TR4482_c0_g1_i2","PRKAG2"]
["transcriptome","GFSG00000000","TR15681_c0_g1_i1","DBX"]
["transcriptome","GFSG00000000","TR12920_c1_g1_i1","Nkx-6.2"]
["transcriptome","GFSG00000000","TR17131_c0_g1_i1","PFY1"]
["transcriptome","GFSG00000000","TR6620_c0_g1_i1","Myc-1"]
["transcriptome","GFSG00000000","TR9144_c0_g1_i1","Aldoc"]
["transcriptome","GFSG00000000","TR24562_c2_g1_i1","Sox2"]
["transcriptome","GFSG00000000","TR2770_c0_g1_i1","PPIB"]
["transcriptome","GFSG00000000","TR23326_c0_g1_i2","RPII15"]
["transcriptome","GFSG00000000","TR27499_c0_g1_i2","Snapin"]
["transcriptome","GFSG00000000","TR7432_c4_g1_i1","Streptavidin-V1"]