Details for gene set KEGG_DORSO_VENTRAL_AXIS_FORMATION[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_DORSO_VENTRAL_AXIS_FORMATION
Enrichment Score (ES) | 0.45142025
Normalized Enrichment Score (NES) | 1.218899
Nominal p-value | 0.2473573
FDR q-value | 0.52419156
FWER p-Value | 0.895
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_DORSO_VENTRAL_AXIS_FORMATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | SOS1 | na |  |  | 3101 | 0.131 | 0.0382 | Yes
2 | NOTCH3 | na |  |  | 3219 | 0.129 | 0.1266 | Yes
3 | NOTCH2 | na |  |  | 9411 | 0.091 | 0.0844 | Yes
4 | GRB2 | na |  |  | 10745 | 0.086 | 0.1213 | Yes
5 | ETV6 | na |  |  | 12281 | 0.080 | 0.1507 | Yes
6 | MAPK3 | na |  |  | 12749 | 0.078 | 0.1973 | Yes
7 | PIWIL3 | na |  |  | 13450 | 0.075 | 0.2380 | Yes
8 | NOTCH1 | na |  |  | 14999 | 0.070 | 0.2603 | Yes
9 | MAPK1 | na |  |  | 15269 | 0.069 | 0.3037 | Yes
10 | PIWIL1 | na |  |  | 16382 | 0.065 | 0.3301 | Yes
11 | NOTCH4 | na |  |  | 16769 | 0.063 | 0.3678 | Yes
12 | ETS1 | na |  |  | 17488 | 0.061 | 0.3982 | Yes
13 | CPEB1 | na |  |  | 17732 | 0.060 | 0.4361 | Yes
14 | PIWIL4 | na |  |  | 19473 | 0.055 | 0.4447 | Yes
15 | SPIRE1 | na |  |  | 21108 | 0.050 | 0.4514 | Yes
16 | PIWIL2 | na |  |  | 22903 | 0.044 | 0.4514 | No
17 | ETV7 | na |  |  | 27906 | 0.029 | 0.3858 | No
18 | MAP2K1 | na |  |  | 29560 | 0.024 | 0.3739 | No
19 | SPIRE2 | na |  |  | 29802 | 0.023 | 0.3856 | No
20 | SOS2 | na |  |  | 33423 | 0.012 | 0.3318 | No
21 | KRAS | na |  |  | 34496 | 0.008 | 0.3188 | No
22 | FMN2 | na |  |  | 42551 | -0.011 | 0.1885 | No
23 | EGFR | na |  |  | 44924 | -0.020 | 0.1621 | No
24 | ETS2 | na |  |  | 56957 | -0.099 | 0.0253 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_DORSO_VENTRAL_AXIS_FORMATION
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_DORSO_VENTRAL_AXIS_FORMATION: Random ES distribution
Gene set null distribution of ES for KEGG_DORSO_VENTRAL_AXIS_FORMATION