Details for gene set KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM
Enrichment Score (ES) | 0.42027244
Normalized Enrichment Score (NES) | 1.2132974
Nominal p-value | 0.2196162
FDR q-value | 0.51485837
FWER p-Value | 0.899
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | BST1 | na |  |  | 2934 | 0.132 | 0.0569 | Yes
2 | NMNAT3 | na |  |  | 5393 | 0.112 | 0.1058 | Yes
3 | AOX1 | na |  |  | 6868 | 0.103 | 0.1643 | Yes
4 | ENPP1 | na |  |  | 8045 | 0.098 | 0.2231 | Yes
5 | NT5C2 | na |  |  | 9139 | 0.092 | 0.2793 | Yes
6 | NT5C1B | na |  |  | 9799 | 0.089 | 0.3403 | Yes
7 | NAMPT | na |  |  | 11094 | 0.084 | 0.3863 | Yes
8 | CD38 | na |  |  | 12799 | 0.078 | 0.4203 | Yes
9 | QPRT | na |  |  | 19954 | 0.054 | 0.3411 | No
10 | NT5M | na |  |  | 20478 | 0.052 | 0.3741 | No
11 | PNP | na |  |  | 25590 | 0.036 | 0.3155 | No
12 | NADK | na |  |  | 32825 | 0.014 | 0.2029 | No
13 | NADSYN1 | na |  |  | 33685 | 0.011 | 0.1968 | No
14 | NT5C1A | na |  |  | 36104 | 0.001 | 0.1562 | No
15 | NUDT12 | na |  |  | 41390 | -0.006 | 0.0706 | No
16 | NMNAT1 | na |  |  | 42276 | -0.010 | 0.0633 | No
17 | ENPP3 | na |  |  | 43423 | -0.014 | 0.0553 | No
18 | NT5C | na |  |  | 45169 | -0.021 | 0.0425 | No
19 | NNT | na |  |  | 46044 | -0.023 | 0.0462 | No
20 | NMNAT2 | na |  |  | 47337 | -0.029 | 0.0472 | No
21 | NNMT | na |  |  | 50647 | -0.044 | 0.0265 | No
22 | NT5E | na |  |  | 58037 | -0.132 | 0.0068 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM: Random ES distribution
Gene set null distribution of ES for KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM