Details for gene set KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM
Enrichment Score (ES) | 0.4673015
Normalized Enrichment Score (NES) | 1.4102306
Nominal p-value | 0.11529934
FDR q-value | 0.40268332
FWER p-Value | 0.733
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | DAO | na |  |  | 1401 | 0.155 | 0.0574 | Yes
2 | SARDH | na |  |  | 3079 | 0.131 | 0.0975 | Yes
3 | CHDH | na |  |  | 3238 | 0.129 | 0.1627 | Yes
4 | PIPOX | na |  |  | 3937 | 0.123 | 0.2155 | Yes
5 | GATM | na |  |  | 4109 | 0.122 | 0.2765 | Yes
6 | ALAS1 | na |  |  | 4578 | 0.118 | 0.3305 | Yes
7 | PSPH | na |  |  | 8769 | 0.094 | 0.3083 | Yes
8 | BHMT | na |  |  | 9765 | 0.090 | 0.3383 | Yes
9 | SDS | na |  |  | 11982 | 0.081 | 0.3429 | Yes
10 | AGXT | na |  |  | 13835 | 0.074 | 0.3500 | Yes
11 | GLYCTK | na |  |  | 14865 | 0.070 | 0.3694 | Yes
12 | GLDC | na |  |  | 15471 | 0.068 | 0.3949 | Yes
13 | AOC3 | na |  |  | 15775 | 0.067 | 0.4250 | Yes
14 | AGXT2 | na |  |  | 17011 | 0.062 | 0.4367 | Yes
15 | GNMT | na |  |  | 17536 | 0.061 | 0.4597 | Yes
16 | PHGDH | na |  |  | 18841 | 0.057 | 0.4673 | Yes
17 | SHMT2 | na |  |  | 20712 | 0.051 | 0.4622 | No
18 | SHMT1 | na |  |  | 22821 | 0.044 | 0.4493 | No
19 | DMGDH | na |  |  | 28428 | 0.027 | 0.3674 | No
20 | AOC2 | na |  |  | 29434 | 0.024 | 0.3628 | No
21 | PSAT1 | na |  |  | 29506 | 0.024 | 0.3741 | No
22 | MAOB | na |  |  | 29563 | 0.023 | 0.3854 | No
23 | DLD | na |  |  | 35596 | 0.003 | 0.2837 | No
24 | MAOA | na |  |  | 35758 | 0.002 | 0.2820 | No
25 | CBS | na |  |  | 41153 | -0.005 | 0.1922 | No
26 | AMT | na |  |  | 42257 | -0.010 | 0.1785 | No
27 | GAMT | na |  |  | 43569 | -0.015 | 0.1638 | No
28 | ALAS2 | na |  |  | 47792 | -0.031 | 0.1078 | No
29 | GCAT | na |  |  | 47899 | -0.032 | 0.1226 | No
30 | SRR | na |  |  | 50276 | -0.042 | 0.1042 | No
31 | CTH | na |  |  | 54326 | -0.068 | 0.0703 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM: Random ES distribution
Gene set null distribution of ES for KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM