Details for gene set KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG
Enrichment Score (ES) | 0.39872557
Normalized Enrichment Score (NES) | 1.1864432
Nominal p-value | 0.23908524
FDR q-value | 0.51675934
FWER p-Value | 0.911
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | BHLHA15 | na |  |  | 1641 | 0.150 | 0.0827 | Yes
2 | HNF1A | na |  |  | 2832 | 0.134 | 0.1608 | Yes
3 | HNF4G | na |  |  | 5723 | 0.110 | 0.1926 | Yes
4 | PAX4 | na |  |  | 7213 | 0.102 | 0.2421 | Yes
5 | PAX6 | na |  |  | 9405 | 0.091 | 0.2718 | Yes
6 | HNF4A | na |  |  | 12874 | 0.078 | 0.2696 | Yes
7 | NR5A2 | na |  |  | 13078 | 0.077 | 0.3228 | Yes
8 | NEUROG3 | na |  |  | 15545 | 0.068 | 0.3307 | Yes
9 | HHEX | na |  |  | 15903 | 0.067 | 0.3737 | Yes
10 | INS | na |  |  | 17121 | 0.062 | 0.3987 | Yes
11 | NEUROD1 | na |  |  | 21649 | 0.048 | 0.3567 | No
12 | ONECUT1 | na |  |  | 23729 | 0.041 | 0.3514 | No
13 | MAFA | na |  |  | 26789 | 0.033 | 0.3231 | No
14 | NKX2-2 | na |  |  | 30826 | 0.021 | 0.2694 | No
15 | HNF1B | na |  |  | 32574 | 0.015 | 0.2504 | No
16 | FOXA3 | na |  |  | 35599 | 0.003 | 0.2007 | No
17 | PKLR | na |  |  | 36105 | 0.001 | 0.1928 | No
18 | NKX6-1 | na |  |  | 41964 | -0.009 | 0.0987 | No
19 | GCK | na |  |  | 44273 | -0.018 | 0.0723 | No
20 | MNX1 | na |  |  | 44437 | -0.018 | 0.0830 | No
21 | IAPP | na |  |  | 48635 | -0.034 | 0.0364 | No
22 | FOXA2 | na |  |  | 48933 | -0.035 | 0.0574 | No
23 | HES1 | na |  |  | 49338 | -0.038 | 0.0785 | No
24 | SLC2A2 | na |  |  | 51476 | -0.049 | 0.0777 | No
25 | PDX1 | na |  |  | 52703 | -0.056 | 0.0981 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG: Random ES distribution
Gene set null distribution of ES for KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG