Details for gene set KEGG_MISMATCH_REPAIR[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | treat
GeneSet | KEGG_MISMATCH_REPAIR
Enrichment Score (ES) | -0.20605412
Normalized Enrichment Score (NES) | -0.46740472
Nominal p-value | 0.93190664
FDR q-value | 0.9636578
FWER p-Value | 0.998
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_MISMATCH_REPAIR
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | RFC5 | na |  |  | 8381 | 0.096 | -0.0620 | Yes
2 | MSH6 | na |  |  | 9077 | 0.093 | 0.0049 | Yes
3 | MSH3 | na |  |  | 9432 | 0.091 | 0.0761 | Yes
4 | MLH3 | na |  |  | 11392 | 0.083 | 0.1131 | Yes
5 | MSH2 | na |  |  | 11453 | 0.083 | 0.1823 | Yes
6 | LIG1 | na |  |  | 18413 | 0.058 | 0.1123 | No
7 | EXO1 | na |  |  | 18671 | 0.057 | 0.1567 | No
8 | RPA1 | na |  |  | 24126 | 0.040 | 0.0973 | No
9 | POLD1 | na |  |  | 26238 | 0.034 | 0.0898 | No
10 | POLD3 | na |  |  | 27318 | 0.031 | 0.0974 | No
11 | PCNA | na |  |  | 29177 | 0.025 | 0.0867 | No
12 | MLH1 | na |  |  | 29232 | 0.025 | 0.1066 | No
13 | RFC3 | na |  |  | 29657 | 0.023 | 0.1190 | No
14 | RPA2 | na |  |  | 30665 | 0.021 | 0.1199 | No
15 | PMS2 | na |  |  | 34097 | 0.009 | 0.0690 | No
16 | RPA4 | na |  |  | 35744 | 0.002 | 0.0426 | No
17 | POLD4 | na |  |  | 40928 | -0.004 | -0.0427 | No
18 | RFC4 | na |  |  | 42178 | -0.009 | -0.0562 | No
19 | RFC2 | na |  |  | 48838 | -0.035 | -0.1404 | No
20 | RFC1 | na |  |  | 52136 | -0.053 | -0.1521 | No
21 | POLD2 | na |  |  | 55290 | -0.076 | -0.1414 | No
22 | RPA3 | na |  |  | 56321 | -0.088 | -0.0840 | No
23 | SSBP1 | na |  |  | 58179 | -0.142 | 0.0043 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_MISMATCH_REPAIR
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_MISMATCH_REPAIR: Random ES distribution
Gene set null distribution of ES for KEGG_MISMATCH_REPAIR