Details for gene set KEGG_RENIN_ANGIOTENSIN_SYSTEM[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_RENIN_ANGIOTENSIN_SYSTEM
Enrichment Score (ES) | 0.47685748
Normalized Enrichment Score (NES) | 1.2015109
Nominal p-value | 0.25523013
FDR q-value | 0.5165904
FWER p-Value | 0.904
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_RENIN_ANGIOTENSIN_SYSTEM
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | ACE | na |  |  | 763 | 0.173 | 0.1273 | Yes
2 | ANPEP | na |  |  | 2489 | 0.138 | 0.2097 | Yes
3 | CPA3 | na |  |  | 2610 | 0.136 | 0.3186 | Yes
4 | MAS1 | na |  |  | 2987 | 0.132 | 0.4194 | Yes
5 | REN | na |  |  | 6097 | 0.108 | 0.4540 | Yes
6 | LNPEP | na |  |  | 9151 | 0.092 | 0.4769 | Yes
7 | NLN | na |  |  | 19840 | 0.054 | 0.3377 | No
8 | CMA1 | na |  |  | 20891 | 0.050 | 0.3608 | No
9 | CTSG | na |  |  | 23648 | 0.041 | 0.3473 | No
10 | ENPEP | na |  |  | 26183 | 0.034 | 0.3315 | No
11 | ACE2 | na |  |  | 27666 | 0.030 | 0.3302 | No
12 | AGTR2 | na |  |  | 32869 | 0.014 | 0.2522 | No
13 | AGTR1 | na |  |  | 37447 | 0.000 | 0.1740 | No
14 | AGT | na |  |  | 44341 | -0.018 | 0.0707 | No
15 | THOP1 | na |  |  | 51684 | -0.050 | -0.0146 | No
16 | MME | na |  |  | 54262 | -0.067 | -0.0041 | No
17 | CTSA | na |  |  | 56600 | -0.093 | 0.0314 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_RENIN_ANGIOTENSIN_SYSTEM
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_RENIN_ANGIOTENSIN_SYSTEM: Random ES distribution
Gene set null distribution of ES for KEGG_RENIN_ANGIOTENSIN_SYSTEM