Details for gene set KEGG_GLYCOSAMINOGLYCAN_DEGRADATION[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION
Enrichment Score (ES) | 0.37658748
Normalized Enrichment Score (NES) | 1.008892
Nominal p-value | 0.46843177
FDR q-value | 0.56137323
FWER p-Value | 0.97
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_GLYCOSAMINOGLYCAN_DEGRADATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | ARSB | na |  |  | 3068 | 0.131 | 0.0464 | Yes
2 | HPSE2 | na |  |  | 4965 | 0.115 | 0.1009 | Yes
3 | HS3ST3B1 | na |  |  | 8127 | 0.097 | 0.1202 | Yes
4 | HEXB | na |  |  | 9060 | 0.093 | 0.1744 | Yes
5 | HYAL4 | na |  |  | 9074 | 0.093 | 0.2442 | Yes
6 | GNS | na |  |  | 10382 | 0.087 | 0.2875 | Yes
7 | HYAL3 | na |  |  | 10432 | 0.087 | 0.3522 | Yes
8 | HYAL2 | na |  |  | 15391 | 0.068 | 0.3189 | Yes
9 | GLB1 | na |  |  | 16981 | 0.063 | 0.3390 | Yes
10 | SPAM1 | na |  |  | 19212 | 0.056 | 0.3429 | Yes
11 | GUSB | na |  |  | 19650 | 0.055 | 0.3766 | Yes
12 | HGSNAT | na |  |  | 24561 | 0.039 | 0.3221 | No
13 | IDS | na |  |  | 27758 | 0.029 | 0.2894 | No
14 | HS3ST3A1 | na |  |  | 29527 | 0.024 | 0.2770 | No
15 | HPSE | na |  |  | 30728 | 0.021 | 0.2725 | No
16 | NAGLU | na |  |  | 34722 | 0.007 | 0.2092 | No
17 | HYAL1 | na |  |  | 49395 | -0.038 | -0.0131 | No
18 | SGSH | na |  |  | 50360 | -0.043 | 0.0027 | No
19 | GALNS | na |  |  | 50406 | -0.043 | 0.0344 | No
20 | HEXA | na |  |  | 53611 | -0.062 | 0.0264 | No
21 | IDUA | na |  |  | 55114 | -0.074 | 0.0568 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_GLYCOSAMINOGLYCAN_DEGRADATION
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_GLYCOSAMINOGLYCAN_DEGRADATION: Random ES distribution
Gene set null distribution of ES for KEGG_GLYCOSAMINOGLYCAN_DEGRADATION