Details for gene set KEGG_ASCORBATE_AND_ALDARATE_METABOLISM[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_ASCORBATE_AND_ALDARATE_METABOLISM
Enrichment Score (ES) | 0.6125472
Normalized Enrichment Score (NES) | 1.6174452
Nominal p-value | 0.031620555
FDR q-value | 0.3999948
FWER p-Value | 0.446
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_ASCORBATE_AND_ALDARATE_METABOLISM
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | UGT1A9 | na |  |  | 1114 | 0.162 | 0.0641 | Yes
2 | UGT2A3 | na |  |  | 1120 | 0.162 | 0.1471 | Yes
3 | UGT2B10 | na |  |  | 2330 | 0.140 | 0.1983 | Yes
4 | UGT1A5 | na |  |  | 5371 | 0.113 | 0.2041 | Yes
5 | UGT2B28 | na |  |  | 6246 | 0.107 | 0.2442 | Yes
6 | UGT1A7 | na |  |  | 6888 | 0.103 | 0.2864 | Yes
7 | UGT1A8 | na |  |  | 7003 | 0.103 | 0.3373 | Yes
8 | UGT1A3 | na |  |  | 7738 | 0.099 | 0.3756 | Yes
9 | UGT2A1 | na |  |  | 7761 | 0.099 | 0.4262 | Yes
10 | UGT2B17 | na |  |  | 8872 | 0.094 | 0.4554 | Yes
11 | ALDH9A1 | na |  |  | 9195 | 0.092 | 0.4973 | Yes
12 | UGT1A1 | na |  |  | 10748 | 0.086 | 0.5148 | Yes
13 | UGT2B7 | na |  |  | 11436 | 0.083 | 0.5457 | Yes
14 | UGT2B11 | na |  |  | 12251 | 0.080 | 0.5727 | Yes
15 | UGT1A4 | na |  |  | 14525 | 0.072 | 0.5706 | Yes
16 | ALDH2 | na |  |  | 15965 | 0.066 | 0.5802 | Yes
17 | UGT2B15 | na |  |  | 16058 | 0.066 | 0.6125 | Yes
18 | UGT1A6 | na |  |  | 21071 | 0.050 | 0.5524 | No
19 | ALDH3A2 | na |  |  | 21342 | 0.049 | 0.5729 | No
20 | MIOX | na |  |  | 24343 | 0.039 | 0.5418 | No
21 | UGT2B4 | na |  |  | 27953 | 0.029 | 0.4947 | No
22 | UGT1A10 | na |  |  | 30927 | 0.020 | 0.4543 | No
23 | UGDH | na |  |  | 31653 | 0.018 | 0.4510 | No
24 | ALDH7A1 | na |  |  | 33991 | 0.010 | 0.4160 | No
25 | ALDH1B1 | na |  |  | 41118 | -0.005 | 0.2964 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_ASCORBATE_AND_ALDARATE_METABOLISM
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_ASCORBATE_AND_ALDARATE_METABOLISM: Random ES distribution
Gene set null distribution of ES for KEGG_ASCORBATE_AND_ALDARATE_METABOLISM