Details for gene set KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | treat
GeneSet | KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS
Enrichment Score (ES) | -0.23518899
Normalized Enrichment Score (NES) | -0.54922307
Nominal p-value | 0.9052224
FDR q-value | 1.0
FWER p-Value | 0.998
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | IDI2 | na |  |  | 3185 | 0.130 | 0.1242 | Yes
2 | PDSS1 | na |  |  | 6886 | 0.103 | 0.2029 | Yes
3 | ACAT1 | na |  |  | 19310 | 0.055 | 0.0665 | No
4 | HMGCR | na |  |  | 20710 | 0.051 | 0.1129 | No
5 | PDSS2 | na |  |  | 28507 | 0.027 | 0.0160 | No
6 | ACAT2 | na |  |  | 30577 | 0.022 | 0.0101 | No
7 | DHDDS | na |  |  | 35547 | 0.003 | -0.0706 | No
8 | FDPS | na |  |  | 40745 | -0.003 | -0.1554 | No
9 | IDI1 | na |  |  | 42739 | -0.012 | -0.1735 | No
10 | HMGCS2 | na |  |  | 46341 | -0.024 | -0.2015 | No
11 | MVK | na |  |  | 47447 | -0.029 | -0.1803 | No
12 | HMGCS1 | na |  |  | 49470 | -0.039 | -0.1617 | No
13 | MVD | na |  |  | 51142 | -0.047 | -0.1257 | No
14 | PMVK | na |  |  | 54900 | -0.072 | -0.0905 | No
15 | GGPS1 | na |  |  | 57450 | -0.110 | 0.0168 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS: Random ES distribution
Gene set null distribution of ES for KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS