Details for gene set KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS
Enrichment Score (ES) | 0.61815757
Normalized Enrichment Score (NES) | 1.6745479
Nominal p-value | 0.014675053
FDR q-value | 0.36582664
FWER p-Value | 0.355
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | CYP27A1 | na |  |  | 686 | 0.176 | 0.1243 | Yes
2 | AKR1D1 | na |  |  | 2006 | 0.145 | 0.2137 | Yes
3 | CYP7B1 | na |  |  | 2063 | 0.144 | 0.3239 | Yes
4 | HSD17B4 | na |  |  | 3788 | 0.124 | 0.3908 | Yes
5 | BAAT | na |  |  | 4376 | 0.119 | 0.4732 | Yes
6 | ACOX2 | na |  |  | 6563 | 0.105 | 0.5171 | Yes
7 | CYP8B1 | na |  |  | 6848 | 0.104 | 0.5924 | Yes
8 | AKR1C4 | na |  |  | 9460 | 0.091 | 0.6182 | Yes
9 | SLC27A5 | na |  |  | 15125 | 0.069 | 0.5748 | No
10 | CYP7A1 | na |  |  | 21707 | 0.048 | 0.4993 | No
11 | CH25H | na |  |  | 23529 | 0.042 | 0.5005 | No
12 | HSD3B7 | na |  |  | 23943 | 0.041 | 0.5248 | No
13 | AMACR | na |  |  | 36247 | 0.001 | 0.3148 | No
14 | CYP46A1 | na |  |  | 40376 | -0.001 | 0.2452 | No
15 | SCP2 | na |  |  | 44721 | -0.020 | 0.1859 | No
16 | CYP39A1 | na |  |  | 53738 | -0.063 | 0.0804 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS: Random ES distribution
Gene set null distribution of ES for KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS