Details for gene set KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION[GSEA]

Dataset | mRNA.symbol.cls#con_versus_treat
Phenotype | symbol.cls#con_versus_treat
Upregulated in class | con
GeneSet | KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION
Enrichment Score (ES) | 0.424497
Normalized Enrichment Score (NES) | 1.212324
Nominal p-value | 0.21784233
FDR q-value | 0.50731057
FWER p-Value | 0.899
Table: GSEA Results Summary

Fig 1: Enrichment plot: KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | ATP1A4 | na |  |  | 3232 | 0.129 | 0.0587 | Yes
2 | GLS2 | na |  |  | 3265 | 0.129 | 0.1720 | Yes
3 | PCK1 | na |  |  | 3708 | 0.125 | 0.2748 | Yes
4 | AQP1 | na |  |  | 4116 | 0.122 | 0.3751 | Yes
5 | PCK2 | na |  |  | 6626 | 0.105 | 0.4245 | Yes
6 | SLC25A10 | na |  |  | 18377 | 0.058 | 0.2746 | No
7 | FXYD2 | na |  |  | 21181 | 0.049 | 0.2702 | No
8 | MDH1 | na |  |  | 21404 | 0.049 | 0.3094 | No
9 | SLC9A3 | na |  |  | 22787 | 0.044 | 0.3249 | No
10 | SLC38A3 | na |  |  | 24839 | 0.038 | 0.3235 | No
11 | ATP1B2 | na |  |  | 25893 | 0.035 | 0.3361 | No
12 | SLC4A4 | na |  |  | 27215 | 0.031 | 0.3409 | No
13 | GLUD2 | na |  |  | 28463 | 0.027 | 0.3431 | No
14 | ATP1A1 | na |  |  | 30551 | 0.022 | 0.3264 | No
15 | ATP1A3 | na |  |  | 31204 | 0.019 | 0.3323 | No
16 | GLS | na |  |  | 32984 | 0.013 | 0.3135 | No
17 | CA4 | na |  |  | 35476 | 0.004 | 0.2740 | No
18 | ATP1B3 | na |  |  | 40588 | -0.002 | 0.1886 | No
19 | ATP1B1 | na |  |  | 41304 | -0.006 | 0.1813 | No
20 | GLUD1 | na |  |  | 41621 | -0.007 | 0.1820 | No
21 | ATP1B4 | na |  |  | 41942 | -0.008 | 0.1840 | No
22 | ATP1A2 | na |  |  | 45326 | -0.022 | 0.1453 | No
23 | CA2 | na |  |  | 56403 | -0.090 | 0.0348 | No
Table: GSEA details [plain text format]

Fig 2: KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION: Random ES distribution
Gene set null distribution of ES for KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION