Supplemental Data

• Supplementary information - Description of supplementary data files
• Supplementary Table 1 - Protein identifications in the experiments for sensitivity evaluation using rat cortex tissue with diameters of 50 µm, 100 µm, and 200 µm. The DMSO evaluation experiments were also included in the table.
• Supplementary Table 2 - Protein identifications for WHIM2 patient derived xenograft tissues with side lengths of 200 µm.
• Supplementary Table 3 - 1. Quantifiable proteins with log2-transformed LFQ intensities in spatially-resolved analysis of three different rat brain regions (cerebral cortex (CTX), corpus callosum (CC), and caudoputamen (CP)). 2. ANOVA significant proteins (q-value, 0.05, and fold change > 4). 3. The protein abundance difference of the average values between each region and all regions.