Charts ID Symbol Description KEGG Pathways FC logFC P.Value adj.P.Val Links absFC dirFC FGF18 FGF18 fibroblast growth factor 18 MAPK signaling pathway Regulation of actin cytoskeleton 27.273 4.769 1.96E-10 5.58E-07   27.27343057 up IGDCC3 IGDCC3 "immunoglobulin superfamily, DCC subclass, member 3" - 25.081 4.649 2.40E-11 1.18E-07   25.08141649 up SCUBE1 SCUBE1 "signal peptide, CUB domain, EGF-like 1" - 23.998 4.585 1.74E-12 1.99E-08   23.99817681 up APOD APOD apolipoprotein D - 23.27 4.54 2.07E-09 2.63E-06   23.26963 up HBAP HBAP "hemoglobin alpha, subunit pi" - 15.614 3.965 2.51E-06 4.73E-04   15.61414125 up BPI BPI bactericidal/permeability-increasing protein - 14.503 3.858 4.10E-09 4.18E-06   14.50302147 up GBX2 GBX2 gastrulation brain homeobox 2 - 14.152 3.823 1.06E-08 6.99E-06   14.15242017 up SALL3 SALL3 spalt-like transcription factor 3 - 11.898 3.573 2.25E-07 8.15E-05   11.8981387 up GREM1 GREM1 "gremlin 1, DAN family BMP antagonist" - 11.432 3.515 6.99E-07 1.90E-04   11.43169044 up ZBTB16 ZBTB16 zinc finger and BTB domain containing 16 - 10.186 3.349 1.07E-06 2.51E-04   10.18646012 up DLX2 DLX2 distal-less homeobox 2 - 10.131 3.341 8.07E-10 1.42E-06   10.13128496 up PKIA PKIA "protein kinase (cAMP-dependent, catalytic) inhibitor alpha" - 9.16 3.195 2.59E-11 1.18E-07   9.160298017 up EGR1 EGR1 early growth response 1 - 8.74 3.128 9.00E-09 6.23E-06   8.740101938 up PHACTR1 PHACTR1 phosphatase and actin regulator 1 - 8.481 3.084 2.64E-06 4.85E-04   8.481328926 up LOC100859704 LOC100859704 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like - 8.322 3.057 1.35E-08 8.31E-06   8.322443356 up HGF HGF hepatocyte growth factor Cytokine-cytokine receptor interaction Focal adhesion 8.179 3.032 3.07E-07 1.03E-04   8.179105088 up ZNF687 ZNF687 zinc finger protein 687 - 7.957 2.992 6.41E-09 4.88E-06   7.957060781 up ACOT9 ACOT9 acyl-CoA thioesterase 9 - 7.655 2.936 3.76E-11 1.43E-07   7.655378112 up LONRF3 LONRF3 LON peptidase N-terminal domain and ring finger 3 - 7.326 2.873 1.82E-06 3.79E-04   7.326037056 up LOC107050935 LOC107050935 calmodulin-binding transcription activator 2-like - 6.996 2.807 5.14E-07 1.51E-04   6.996244559 up PLEK PLEK pleckstrin - 6.249 2.644 1.30E-11 9.90E-08   6.249200855 up PHLDA1 PHLDA1 pleckstrin homology like domain family A member 1 - 5.978 2.58 2.18E-08 1.13E-05   5.97847211 up NPY2R NPY2R neuropeptide Y receptor Y2 Neuroactive ligand-receptor interaction 5.432 2.442 3.56E-09 4.06E-06   5.43234837 up LOC107055618 LOC107055618 basic proline-rich protein-like - 5.217 2.383 1.55E-06 3.37E-04   5.21717387 up LOC107055593 LOC107055593 uncharacterized LOC107055593 - 5.131 2.359 1.08E-06 2.52E-04   5.130558056 up NPM3 NPM3 nucleophosmin/nucleoplasmin 3 - 4.895 2.291 2.95E-09 3.55E-06   4.895005357 up LIN28B LIN28B lin-28 homolog B (C. elegans) - 4.295 2.103 1.86E-09 2.50E-06   4.295022205 up SALL1 SALL1 sal-like 1 (Drosophila) - 3.854 1.946 1.34E-08 8.31E-06   3.8540825 up EPHA4 EPHA4 EPH receptor A4 - 3.514 1.813 1.75E-09 2.50E-06   3.514405198 up ENPP1 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 Purine metabolism Starch and sucrose metabolism Riboflavin metabolism Nicotinate and nicotinamide metablism Pantothenate and CoA biosynthesis 3.469 1.794 1.01E-06 2.42E-04   3.468951123 up PHLDA2 PHLDA2 pleckstrin homology like domain family A member 2 - 3.361 1.749 1.99E-08 1.06E-05   3.361273522 up KERA KERA keratocan - 3.296 1.721 1.53E-08 8.94E-06   3.295635377 up CAMKK1 CAMKK1 "calcium/calmodulin-dependent protein kinase kinase 1, alpha" Adipocytokine signaling pathway 3.236 1.694 6.12E-08 2.69E-05   3.235680489 up FGF13 FGF13 fibroblast growth factor 13 MAPK signaling pathway Regulation of actin cytoskeleton 3.12 1.642 2.86E-08 1.36E-05   3.120277239 up PRTG PRTG protogenin - 2.968 1.569 1.14E-06 2.62E-04   2.967911152 up SALL4 SALL4 spalt-like transcription factor 4 - 2.942 1.557 1.71E-08 9.52E-06   2.941745096 up PROM1 PROM1 prominin 1 - 2.873 1.522 4.70E-09 4.18E-06   2.872788275 up SMCO4 SMCO4 single-pass membrane protein with coiled-coil domains 4 - 2.868 1.52 2.23E-06 4.35E-04   2.868024597 up GREB1 GREB1 growth regulation by estrogen in breast cancer 1 - 2.839 1.505 2.32E-06 4.44E-04   2.83881827 up AGPAT5 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 Glycerolipid metabolism Glycerophospholipid metabolism 2.764 1.467 1.73E-07 6.69E-05   2.764323572 up TP53I11 TP53I11 tumor protein p53 inducible protein 11 - 2.668 1.416 6.38E-09 4.88E-06   2.668475451 up TBC1D7 TBC1D7 TBC1 domain family member 7 - 2.62 1.39 2.13E-07 7.85E-05   2.620129958 up RFTN1 RFTN1 "raftlin, lipid raft linker 1" - 2.605 1.382 2.53E-06 4.73E-04   2.605467708 up MAPK11 MAPK11 mitogen-activated protein kinase 11 MAPK signaling pathway FoxO signaling pathway Adrenergic signaling VEGF signaling pathway Toll-like receptor signaling pathway NOD-like receptor signaling pathway receptor signaling GnRH signaling pathway Progesterone-mediated oocyte maturation Salmonella infection Influenza A 2.588 1.372 1.63E-09 2.48E-06   2.588130988 up RHOU RHOU ras homolog family member U - 2.563 1.358 7.60E-09 5.60E-06   2.563215192 up TFRC TFRC "transferrin receptor (p90, CD71)" Endocytosis Phagosome 2.525 1.336 4.10E-07 1.27E-04   2.524960851 up WFDC1 WFDC1 WAP four-disulfide core domain 1 - 2.515 1.331 2.68E-08 1.30E-05   2.514903152 up KIF26A KIF26A kinesin family member 26A - 2.49 1.316 4.68E-09 4.18E-06   2.490198766 up NRP1 NRP1 neuropilin 1 - 2.481 1.311 4.08E-07 1.27E-04   2.481258568 up PGK1 PGK1 phosphoglycerate kinase 1 Glycolysis Gluconeogenesis 2.35 1.233 1.64E-10 5.34E-07   2.349965634 up HOXA10-AS HOXA10-AS HOXA10 antisense RNA - 2.213 1.146 1.86E-06 3.79E-04   2.212538306 up IL17RD IL17RD interleukin 17 receptor D - 2.183 1.126 8.64E-09 6.17E-06   2.182507428 up SLC25A22 SLC25A22 "solute carrier family 25 (mitochondrial carrier: glutamate), member 22" - 2.176 1.122 1.40E-06 3.11E-04   2.176064871 up TRIL TRIL TLR4 interactor with leucine-rich repeats - 2.081 1.058 6.69E-07 1.86E-04   2.081479948 up TSC22D1 TSC22D1 "TSC22 domain family, member 1" - -2.054 -1.039 1.54E-06 3.37E-04   2.054178307 down LMO7 LMO7 LIM domain 7 Adherens junction -2.058 -1.041 5.05E-07 1.50E-04   2.058027376 down PDGFRA PDGFRA "platelet-derived growth factor receptor, alpha polypeptide" MAPK signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interatction Endocytosis Focal adhesion Gap junction Regulation of actin cytoskeleton -2.088 -1.062 1.29E-06 2.91E-04   2.088013329 down LOC107051702 LOC107051702 uncharacterized LOC107051702 - -2.25 -1.17 2.10E-06 4.20E-04   2.249666265 down FGFR2 FGFR2 fibroblast growth factor receptor 2 MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton -2.267 -1.181 9.32E-08 3.94E-05   2.266943551 down ITGA2 ITGA2 "integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" Phagosome Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton -2.274 -1.185 3.22E-07 1.07E-04   2.273952871 down COL25A1 COL25A1 "collagen, type XXV, alpha 1" - -2.308 -1.207 8.23E-07 2.09E-04   2.308203701 down LOC107055688 LOC107055688 collagen alpha-1(I) chain-like - -2.333 -1.222 2.56E-06 4.76E-04   2.333414679 down NCKAP5 NCKAP5 NCK associated protein 5 - -2.344 -1.229 2.40E-06 4.57E-04   2.344195594 down FAM101A FAM101A family with sequence similarity 101 member A - -2.443 -1.288 1.47E-08 8.80E-06   2.442730112 down NEDD9 NEDD9 "neural precursor cell expressed, developmentally down-regulated 9" - -2.447 -1.291 1.07E-08 6.99E-06   2.447348713 down SESN3 SESN3 sestrin 3 p53 signaling pathway -2.47 -1.304 6.15E-09 4.88E-06   2.469588968 down FBLN1 FBLN1 fibulin 1 - -2.488 -1.315 7.85E-10 1.42E-06   2.488487247 down LAMA4 LAMA4 "laminin, alpha 4" Focal adhesion ECM-receptor interaction -2.504 -1.324 9.70E-07 2.36E-04   2.504355645 down CSRNP1 CSRNP1 cysteine-serine-rich nuclear protein 1 - -2.612 -1.385 2.15E-06 4.27E-04   2.611789353 down PTPRT PTPRT "protein tyrosine phosphatase, receptor type, T" - -2.707 -1.437 3.83E-07 1.23E-04   2.707445332 down SSBP2 SSBP2 single-stranded DNA binding protein 2 - -2.713 -1.44 5.01E-07 1.50E-04   2.712781847 down ARHGAP18 ARHGAP18 Rho GTPase activating protein 18 - -2.907 -1.539 5.75E-09 4.87E-06   2.906803866 down COL3A1 COL3A1 "collagen, type III, alpha 1" Focal adhesion ECM-receptor interaction -2.993 -1.582 1.76E-08 9.59E-06   2.993360047 down LOC422301 LOC422301 zinc finger protein 185-like - -3.005 -1.587 2.76E-07 9.55E-05   3.004681231 down LOC101750014 LOC101750014 uncharacterized LOC101750014 - -3.023 -1.596 1.05E-06 2.50E-04   3.023299354 down PCDH10 PCDH10 protocadherin 10 - -3.092 -1.629 3.65E-08 1.70E-05   3.092258185 down POSTN POSTN "periostin, osteoblast specific factor" - -3.093 -1.629 6.16E-07 1.78E-04   3.09287447 down MXRA5 MXRA5 matrix-remodelling associated 5 - -3.138 -1.65 2.91E-07 9.92E-05   3.137973827 down ARIH1 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 - -3.227 -1.69 4.05E-09 4.18E-06   3.227292091 down RELN RELN reelin Focal adhesion ECM-receptor interaction -3.252 -1.701 2.56E-07 8.98E-05   3.252233477 down PAPLN PAPLN "papilin, proteoglycan-like sulfated glycoprotein" - -3.848 -1.944 6.51E-08 2.81E-05   3.848389882 down HTR1B HTR1B "5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled" Neuroactive ligand-receptor interaction -3.999 -2 5.16E-08 2.31E-05   3.999139787 down COL17A1 COL17A1 "collagen, type XVII, alpha 1" - -4.174 -2.062 4.58E-10 9.52E-07   4.174418996 down BAMBI BAMBI BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) Wnt signaling pathway TGF-beta signaling pathway -4.47 -2.16 2.81E-10 7.13E-07   4.469503962 down LGR5 LGR5 leucine-rich repeat containing G protein-coupled receptor 5 - -4.495 -2.168 2.54E-08 1.26E-05   4.494646584 down ZEB2 ZEB2 zinc finger E-box binding homeobox 2 - -4.744 -2.246 4.91E-08 2.24E-05   4.743866829 down LOC107051213 LOC107051213 uncharacterized LOC107051213 - -5.447 -2.446 7.76E-07 1.99E-04   5.447278934 down SIRT4 SIRT4 sirtuin 4 - -5.708 -2.513 2.41E-08 1.22E-05   5.708112452 down LOC416696 LOC416696 "collagen, type VII, alpha 1-like" - -5.854 -2.549 1.59E-12 1.99E-08   5.854253728 down LOC107053920 LOC107053920 uncharacterized LOC107053920 - -6.011 -2.588 9.23E-10 1.51E-06   6.010750925 down HOXC13 HOXC13 homeobox C13 - -6.077 -2.603 1.71E-06 3.65E-04   6.077005385 down RDH10 RDH10 retinol dehydrogenase 10 (all-trans) Retinol metabolism -7.873 -2.977 7.63E-07 1.99E-04   7.872518909 down A4GALT A4GALT "alpha 1,4-galactosyltransferase" - -10.745 -3.426 8.43E-07 2.12E-04   10.74533171 down MAPK10 MAPK10 mitogen-activated protein kinase 10 MAPK signaling pathway ErbB signaling pathway FoxO signaling pathway Protein processing in endoplasmic reticulum Wnt signaling pathway Focal adhesion Toll-like receptor signaling NOD-like receptor signaling pathway Insulin signaling pathway GnRH signaling pathway Progesterone-mediated oocyte maturation Adipocytokine signaling pathway Salmonella infection Influenza A Herpes simplex infection -12.379 -3.63 1.67E-07 6.56E-05   12.37923417 down ADGRD1 ADGRD1 adhesion G protein-coupled receptor D1 - -14.786 -3.886 1.42E-07 5.77E-05   14.78628727 down LIMCH1 LIMCH1 LIM and calponin homology domains 1 - -15.868 -3.988 3.87E-10 8.83E-07   15.86843463 down GRID2 GRID2 "glutamate receptor, ionotropic, delta 2" Neuroactive ligand-receptor interaction -17.35 -4.117 9.35E-07 2.30E-04   17.35019517 down PDGFD PDGFD platelet derived growth factor D Focal adhesion Gap junction Regulation of actin cytoskeleton -17.545 -4.133 4.76E-09 4.18E-06   17.54496435 down LOC107057199 LOC107057199 borealin-like - -53.424 -5.739 4.34E-09 4.18E-06   53.42379605 down