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{"sheet":"Table S2","index":0,"n_rows":270,"n_cols":7,"rows_kept":270,"cut":false,"hidden":false,"merged":[[0,0,0,2],[0,4,0,6]]}
["Significant gradient serum metabolites before HFD",null,null,null,"Significant gradient serum metabolites after HFD"]
["Biochemical Name","Fold Change (log2) Evening/Morning","p-value (-log10)",null,"Biochemical Name","Fold Change (log2) Evening/Morning","p-value (-log10)"]
["N-(2-furoyl)glycine",2.7026575433909108,9.7731166716090829,null,"caprate (10:0)",2.8339020766691636,8.3351042901163535]
["prolylglycine",1.8073549220576042,8.862930869160591,null,"maleate",1.4222330006830479,7.8808431253096956]
["caffeic acid sulfate",3.0356239097307216,6.2669472561769419,null,"10-nonadecenoate (19:1n9)",1.4802651220544629,7.5760172703228239]
["N-acetylglutamate",1.0426443374084939,6.2480745556457764,null,"dihydroferulic acid",3.2125693388508059,7.5642033962989332]
["5-hydroxylysine",1.7180875839605168,6.2329109535936036,null,"beta-alanine",1.1890338243900169,7.5092271040944487]
["4-hydroxyphenylpyruvate",1.1110313123887441,6.1621717560316007,null,"ceramide (d18:1/14:0, d16:1/16:0)*",0.51601514700366469,7.4975455667561075]
["glycerophosphoglycerol",1.5058909297299574,5.9994791590638146,null,"N-methylalanine",1.0214797274104515,7.4602090336542588]
["methionine sulfoxide",0.90303827011291216,5.9649707177976321,null,"stearate (18:0)",1.2448870591235344,7.4482938926104003]
["1-linoleoyl-GPE (18:2)*",1.1309308698264486,5.7345453641568165,null,"caprylate (8:0)",3.1176950426697547,7.3255062827036497]
["N-palmitoyl-heptadecasphingosine (d17:1/16:0)*",0.70487196445635281,5.633614403046054,null,"15-methylpalmitate",1.7824085649273733,6.931443104927637]
["ceramide (d18:1/14:0, d16:1/16:0)*",0.41142624572646502,5.6288212681837129,null,"caffeic acid sulfate",3.1890338243900169,6.6966095258866112]
["N-ethylglycinexylidide",1.9068905956085187,5.6218383904450873,null,"laurate (12:0)",2.6158870739160567,6.5591381264224538]
["creatine",0.65076455911690234,5.3870466955676575,null,"lidocaine",4.3923174227787607,6.5228787452803374]
["tyrosine",0.41142624572646502,5.3682519256034302,null,"prolylglycine",1.4222330006830479,6.5223723637166255]
["proline",0.58496250072115619,5.1796671551005904,null,"methylsuccinate",0.62293035092017679,6.5213325174316514]
["serine",0.40053792958372886,5.0840517065581698,null,"dodecanedioate",2.4032677223393013,6.3627605122010698]
["pyrraline",1.5753123306874368,4.9684703541965769,null,"lanthionine",1.6040713236688608,6.2765689578398778]
["beta-alanine",0.87184364850931773,4.9338978032332266,null,"nonadecanoate (19:0)",1.1763227726404628,6.1971920796383717]
["N-stearoyl-sphingadienine (d18:2/18:0)*",0.66902676550963081,4.8591464186772777,null,"azelate (nonanedioate)",1.925999418556223,6.19114785246488]
["12,13-DiHOME",1.5607149544744789,4.8097803922889453,null,"12,13-DiHOME",1.8599695482210259,6.1569853585530314]
["N-palmitoyl-sphinganine (d18:0/16:0)",1.0071955014042038,4.7452344675838525,null,"myristate (14:0)",1.8875252707415877,5.858205436476343]
["isoleucine",0.40053792958372886,4.6604889342536922,null,"N-(2-furoyl)glycine",1.8032270364349277,5.8054301607713574]
["gamma-glutamylmethionine",0.77399632511117322,4.6126457730286337,null,"3-hydroxybutyrate (BHBA)",1.713695814843359,5.7553271215838899]
["2-keto-3-deoxy-gluconate",0.48542682717024171,4.5480294503705414,null,"acetoacetate",1.8559896973084806,5.7496043969428836]
["cytosine",1.8073549220576042,4.5105759330745911,null,"methionine sulfoxide",0.87970576628228825,5.748678187684412]
["taurocholate",2.639232163249277,4.5089886849518992,null,"arachidate (20:0)",0.67807190511263782,5.6457378554955167]
["tauroursodeoxycholate",1.4594316186372973,4.4643135461764425,null,"cortisone",-1.6438561897747248,5.6294869104014076]
["cortisone",-1.3959286763311392,4.4489893984264892,null,"N-ethylglycinexylidide",1.9030382701129123,5.6136794261059535]
["androstenediol (3alpha, 17alpha) monosulfate (2)",-0.97143084780322919,4.4238084323381655,null,"5-hydroxylysine",1.5801454844233804,5.5426480538893061]
["phenyllactate (PLA)",0.69599381310990016,4.381146850513197,null,"margarate (17:0)",1.2141248053528473,5.5232408082291133]
["glycodeoxycholate",2.5655971758542253,4.3782111510491584,null,"phytanate",1.9183862344463478,5.4604095794660843]
["mannose",-0.37706964907982332,4.3424374470856186,null,"13-methylmyristate",2.2418401835646709,5.2854606892341014]
["5-oxoproline",0.57531233068743692,4.3338565727084415,null,"cortisol",-1.6896598793878495,4.9805098370024927]
["asparagine",0.32192809488736235,4.3279945549770478,null,"citraconate/glutaconate",1.2265085298086797,4.9416499077893468]
["caprate (10:0)",1.7484612330040357,4.3211630730990782,null,"N-acetyl-1-methylhistidine*",-1.5994620704162712,4.8936730881780335]
["taurodeoxycholate",2.8135246892978105,4.2861735756194754,null,"tauroursodeoxycholate",1.5459683691052926,4.8604987252640903]
["taurochenodeoxycholate",2.7990873060740036,4.2105109505643643,null,"suberate (octanedioate)",1.5801454844233804,4.8520764610193936]
["glycocholate",2.4356285940520905,4.0987378910686161,null,"3-hydroxyoctanoate",0.98550043030488488,4.7920157532338434]
["spermidine",-1.3959286763311392,4.0791152383028368,null,"pentadecanoate (15:0)",1.2630344058337937,4.7619790013240513]
["chiro-inositol",2.3561438102252752,4.0444276921331879,null,"17-methylstearate",1.1890338243900169,4.7271377244110937]
["1-arachidonoyl-GPE (20:4n6)*",0.60407132366886085,4.041412228849647,null,"pristanate",1.7697717392494476,4.6545282456323696]
["N-methylalanine",0.65076455911690234,4.014919482444415,null,"3-hydroxyisobutyrate",1.0635029423061579,4.5864487868244499]
["cortisol",-1.4344028241457749,4.0145690347873568,null,"1-myristoylglycerol (14:0)",1.6135316529179271,4.5744331760347414]
["hydantoin-5-propionic acid",0.94110631094643149,4,null,"N-palmitoyl-sphinganine (d18:0/16:0)",0.97819562968165163,4.5298542241003039]
["phenylalanine",0.23878685958711648,4,null,"sebacate (decanedioate)",0.91838623444634793,4.5029735454757231]
["methionine",0.42223300068304781,4,null,"behenate (22:0)*",0.72246602447109098,4.3895634283814893]
["glucose",0.26303440583379378,4,null,"eicosenoate (20:1)",1.0071955014042038,4.3393336983199564]
["1-linoleoyl-GPC (18:2)",0.32192809488736235,4,null,"choline phosphate",0.54596836910529256,4.3160169043209775]
["N-palmitoyl-sphingosine (d18:1/16:0)",0.50589092972995731,4,null,"3-methyl catechol sulfate (1)",2.1953475983222193,4.3138554945764396]
["glycochenodeoxycholate",2.2203299548795559,4,null,"1-linoleoyl-GPE (18:2)*",0.91838623444634793,4.2927620584941186]
["glycolithocholate",2.5385381636298039,4,null,"palmitate (16:0)",0.83187724119167306,4.2890030850837775]
["pyridoxate",0.90303827011291216,4,null,"3-methyladipate",1.2570106182060239,4.2439423219792376]
["gamma-glutamylhistidine",0.35614381022527536,3.6989700043360187,null,"adipate",0.91073266190291258,4.2101444156707624]
["gamma-glutamyl-alpha-lysine",0.46466826700344421,3.6989700043360187,null,"creatine",0.5360529002402098,4.1435792720322491]
["3-hydroxy-3-methylglutarate",0.57531233068743692,3.6989700043360187,null,"N-palmitoyl-sphingosine (d18:1/16:0)",0.52606881166758768,4.077217470018546]
["N1-methylinosine",-0.30400618689009989,3.6989700043360187,null,"dopamine 3-O-sulfate",1.1176950426697545,4.0725988370260744]
["dimethylglycine",0.43295940727610632,3.5228787452803374,null,"N-acetylglutamate",0.76553474636297703,4.0159635141553247]
["leucine",0.3334237337251918,3.5228787452803374,null,"orotate",0.55581615506163962,4.0067269361480982]
["(N(1) + N(8))-acetylspermidine",-0.71311885221183846,3.5228787452803374,null,"deoxycarnitine",-0.18442457113742744,4]
["fructose",0.82374936030827284,3.5228787452803374,null,"2-hydroxynervonate*",0.72246602447109098,4]
["caprylate (8:0)",1.8718436485093179,3.5228787452803374,null,"androstenediol (3alpha, 17alpha) monosulfate (2)",-0.88896868761125614,4]
["N-palmitoyl-sphingadienine (d18:2/16:0)*",0.34482849699744117,3.5228787452803374,null,"glycochenodeoxycholate glucuronide (1)",1.3895668117627258,4]
["glycoursodeoxycholate",1.6507645591169022,3.5228787452803374,null,"cis-4-decenoylcarnitine (C10:1)",-0.97143084780322919,3.6989700043360187]
["N2,N2-dimethylguanosine",-0.32192809488736229,3.5228787452803374,null,"stearoyl ethanolamide",0.64154602908752378,3.6989700043360187]
["2-isopropylmalate",2.1890338243900169,3.5228787452803374,null,"1-palmitoyl-2-oleoyl-GPI (16:0/18:1)*",0.52606881166758768,3.6989700043360187]
["gamma-glutamyltyrosine",0.76553474636297703,3.3979400086720375,null,"pyrraline",1.304511041809953,3.6989700043360187]
["1,2-dilinoleoyl-GPC (18:2/18:2)",0.47508488294878265,3.3979400086720375,null,"phenylalanine",0.21412480535284734,3.5228787452803374]
["1-palmitoyl-GPE (16:0)",0.51601514700366469,3.3979400086720375,null,"acisoga",-0.97143084780322919,3.5228787452803374]
["valine",0.2509615735332188,3.3010299956639813,null,"5-dodecenoate (12:1n7)",0.97085365434048343,3.5228787452803374]
["sucrose",2.4356285940520905,3.3010299956639813,null,"dihomo-linoleate (20:2n6)",0.73984810269932755,3.5228787452803374]
["fumarate",0.37851162325372983,3.2218487496163566,null,"erucate (22:1n9)",0.73118324157220005,3.3979400086720375]
["1-palmitoyl-GPC (16:0)",0.27500704749986982,3.1549019599857431,null,"hexadecanedioate",0.81557542886257262,3.3979400086720375]
["1-oleoyl-GPE (18:1)",0.91073266190291258,3.1549019599857431,null,"carnitine",-0.21759143507262679,3.3979400086720375]
["gamma-glutamylvaline",0.35614381022527536,3.0969100130080562,null,"myristoylcarnitine (C14)",0.62293035092017679,3.3010299956639813]
["aconitate [cis or trans]",0.56559717585422509,3.0457574905606752,null,"9,10-DiHOME",1.1505596765753814,3.3010299956639813]
["myristoylcarnitine (C14)",0.5945485495503543,3.0457574905606752,null,"1-oleoyl-GPE (18:1)",0.93357263826102388,3.3010299956639813]
["dihomo-linoleoylcarnitine (C20:2)*",0.45417589318580209,3.0457574905606752,null,"3-hydroxydecanoate",0.75702324650745967,3.2218487496163566]
["alpha-ketoglutarate",0.34482849699744117,3,null,"16-hydroxypalmitate",0.79077203786200001,3.2218487496163566]
["glycohyocholate",1.4594316186372973,2.9586073148417751,null,"nicotinamide",-1,3.2218487496163566]
["methylmalonate (MMA)",0.36737106564852945,2.9208187539523753,null,"N-acetyltryptophan",-1.0892673380970874,3.1549019599857431]
["margaroylcarnitine*",0.57531233068743692,2.8860566476931631,null,"3-hydroxypyridine sulfate",1.875780063068488,3.1549019599857431]
["cysteine sulfinic acid",-0.49410907027004275,2.8538719643217618,null,"docosadienoate (22:2n6)",0.61353165291792711,3.0969100130080562]
["docosapentaenoylcarnitine (C22:5n3)*",0.63226821549951295,2.7695510786217259,null,"hydantoin-5-propionic acid",0.79077203786200001,3.0457574905606752]
["N1-methyladenosine",-0.2515387669959645,2.744727494896694,null,"indole-3-carboxylic acid",-0.81096617560998319,3.0457574905606752]
["glutamate",0.5360529002402098,2.7212463990471711,null,"2-hydroxybutyrate/2-hydroxyisobutyrate",0.63226821549951295,3.0457574905606752]
["ornithine",0.26303440583379378,2.6989700043360187,null,"1-methylnicotinamide",-1,3.0457574905606752]
["heme",-1.5994620704162712,2.6989700043360187,null,"taurochenodeoxycholate",2.2172307162206693,3]
["sphingomyelin (d17:2/16:0, d18:2/15:0)*",0.50589092972995731,2.6777807052660809,null,"N-acetyl-aspartyl-glutamate (NAAG)",0.60407132366886085,2.9586073148417751]
["anthranilate",-0.66657626627480826,2.6575773191777938,null,"10-undecenoate (11:1n1)",0.60407132366886085,2.9586073148417751]
["1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)*",0.31034012061215049,2.6382721639824069,null,"13-HODE + 9-HODE",1.5509006646475234,2.9586073148417751]
["glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH))*",0.48542682717024171,2.6197887582883941,null,"deoxycholate",1.3729520979118293,2.9586073148417751]
["glycochenodeoxycholate glucuronide (1)",1.0496307677246004,2.6197887582883941,null,"eicosapentaenoylcholine",-1.0291463456595165,2.8860566476931631]
["stachydrine",1.7865963618908067,2.6020599913279625,null,"S-methylmethionine",2.3561438102252752,2.8538719643217618]
["dihomo-linolenoylcarnitine (20:3n3 or 6)*",0.34482849699744117,2.5850266520291822,null,"1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)",0.46466826700344421,2.8538719643217618]
["4-acetylphenol sulfate",0.69599381310990016,2.5850266520291822,null,"glutamate",0.54596836910529256,2.8239087409443187]
["S-1-pyrroline-5-carboxylate",0.47508488294878265,2.5228787452803374,null,"ornithine",0.26303440583379378,2.8239087409443187]
["tyramine O-sulfate",2.0461417816447205,2.5228787452803374,null,"1,2-dipalmitoyl-GPE (16:0/16:0)*",1.3950627995175777,2.8239087409443187]
["arginine",0.26303440583379378,2.5228787452803374,null,"glycochenodeoxycholate",1.8114710305298358,2.8239087409443187]
["oleoylcarnitine (C18:1)",0.38956681176272562,2.5086383061657274,null,"pimelate (heptanedioate)",1.4646682670034441,2.795880017344075]
["1-methylnicotinamide",-0.88896868761125614,2.5086383061657274,null,"glycoursodeoxycholate",1.411426245726465,2.795880017344075]
["13-HODE + 9-HODE",1.3729520979118293,2.4948500216800942,null,"guanine",0.73984810269932755,2.744727494896694]
["1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*",1.1699250014423124,2.4948500216800942,null,"glycodeoxycholate",1.8599695482210259,2.7212463990471711]
["linoleoylcarnitine (C18:2)*",0.36737106564852945,2.4814860601221125,null,"acetylcarnitine (C2)",0.5945485495503543,2.6989700043360187]
["9,10-DiHOME",0.94860084749335571,2.4685210829577451,null,"proline",0.36737106564852945,2.6777807052660809]
["stearoylcarnitine (C18)",0.40053792958372886,2.4559319556497243,null,"docosatrienoate (22:3n3)",1.5008020530571577,2.6777807052660809]
["phenylpyruvate",0.48542682717024171,2.4436974992327127,null,"N-formylanthranilic acid",0.65076455911690234,2.6575773191777938]
["hexadecanedioate",0.65992455840237829,2.4436974992327127,null,"imidazole propionate",0.5360529002402098,2.6382721639824069]
["N-methylproline",1.5509006646475234,2.431798275933005,null,"gamma-glutamylphenylalanine",0.84799690655495008,2.6382721639824069]
["N-stearoyl-sphinganine (d18:0/18:0)*",0.71369581484335898,2.3979400086720375,null,"gamma-glutamylvaline",0.32192809488736235,2.6382721639824069]
["hydroquinone sulfate",1.0772429989324603,2.3665315444204134,null,"1-arachidonoyl-GPE (20:4n6)*",0.44360665147561484,2.6020599913279625]
["betaine",0.18903382439001684,2.3565473235138126,null,"glycerate",0.29865831556451516,2.5686362358410126]
["1-myristoylglycerol (14:0)",1.0214797274104515,2.3187587626244128,null,"nervonate (24:1n9)*",0.42223300068304781,2.5686362358410126]
["glycerate",0.27500704749986982,2.2676062401770314,null,"1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)*",0.89530262133330685,2.5686362358410126]
["ceramide (d18:1/17:0, d17:1/18:0)*",0.49569516262406882,2.2596373105057563,null,"1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*",1.1890338243900169,2.5528419686577806]
["N-acetylaspartate (NAA)",0.27500704749986982,2.2291479883578558,null,"taurodeoxycholate",1.9745293124838819,2.5376020021010439]
["4-vinylguaiacol sulfate",1.8278190246173196,2.2076083105017461,null,"indolelactate",-0.39592867633113921,2.5228787452803374]
["1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6)",0.23878685958711648,2.2006594505464183,null,"myristoleate (14:1n5)",1.0214797274104515,2.4814860601221125]
["dopamine 3-O-sulfate",0.73118324157220005,2.1938200260161129,null,"pregnenolone sulfate",-0.71311885221183846,2.4814860601221125]
["N-stearoyl-sphingosine (d18:1/18:0)*",0.38956681176272562,2.1804560644581312,null,"oleate/vaccenate (18:1)",0.64154602908752378,2.4685210829577451]
["imidazole lactate",0.17632277264046289,2.1249387366082999,null,"1,2-dilinoleoyl-GPC (18:2/18:2)",0.37851162325372983,2.4685210829577451]
["gluconate",0.32192809488736235,2.1191864077192086,null,"isobutyrylcarnitine (C4)",0.46466826700344421,2.431798275933005]
["palmitoloelycholine",-0.78587519464715272,2.1023729087095586,null,"4-guanidinobutanoate",0.94110631094643149,2.431798275933005]
["oleoylcholine",-0.6438561897747247,2.0915149811213505,null,"2-aminophenol sulfate",1.3103401206121505,2.431798275933005]
["lactate",0.38956681176272562,2.0809219076239263,null,"N-acetylneuraminate",0.57531233068743692,2.4202164033831899]
["4-methyl-2-oxopentanoate",0.41142624572646502,2.0757207139381184,null,"margaroylcarnitine*",0.51601514700366469,2.3979400086720375]
["2-hydroxy-3-methylvalerate",0.70487196445635281,2.0705810742857071,null,"taurocholate",1.7224660244710912,2.3979400086720375]
["eicosapentaenoylcholine",-0.81096617560998319,2.0604807473813813,null,"glycolithocholate",1.790772037862,2.3872161432802645]
["indole-3-carboxylic acid",-0.62148837674627011,2.0457574905606752,null,"1-stearoyl-2-linoleoyl-GPI (18:0/18:2)",0.34482849699744117,2.3767507096020997]
["histidine",0.21412480535284734,2.0177287669604316,null,"1-myristoyl-2-palmitoyl-GPC (14:0/16:0)",0.76553474636297703,2.3665315444204134]
["palmitoylcholine",-0.57776699931695219,1.9871627752948278,null,"L-urobilin",1.5509006646475234,2.3665315444204134]
["linoleoylcholine*",-0.53533173299655579,1.9871627752948278,null,"1-palmitoyl-2-oleoyl-GPE (16:0/18:1)",0.81557542886257262,2.3565473235138126]
["1,2-dipalmitoyl-GPC (16:0/16:0)",0.31034012061215049,1.9706162223147903,null,"N-palmitoyl-heptadecasphingosine (d17:1/16:0)*",0.38956681176272562,2.3565473235138126]
["sphingomyelin (d18:2/14:0, d18:1/14:1)*",0.40053792958372886,1.9393021596463884,null,"1-linolenoyl-GPC (18:3)*",0.64154602908752378,2.3279021420642825]
["N-acetylmethionine",0.32192809488736235,1.9244530386074692,null,"gamma-glutamylhistidine",0.26303440583379378,2.3187587626244128]
["arachidoylcarnitine (C20)*",0.60407132366886085,1.9244530386074692,null,"N-acetylarginine",-0.37706964907982332,2.3098039199714862]
["ethyl glucuronide",-1.0588936890535685,1.8996294548824371,null,"hexanoylglutamine",1.1634987322828796,2.3010299956639813]
["palmitoyl-linoleoyl-glycerol (16:0/18:2) [1]*",1.207892851641333,1.8927900303521317,null,"1-linoleoyl-GPI (18:2)*",0.78240856492737332,2.3010299956639813]
["ascorbate (Vitamin C)",0.74846123300403555,1.8794260687941502,null,"linoleoylcholine*",-0.57776699931695219,2.2924298239020637]
["1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)",0.18903382439001684,1.8664610916297826,null,"quinate",1.5410191531335593,2.2924298239020637]
["pyruvate",0.65076455911690234,1.8632794328435933,null,"octanoylcarnitine (C8)",-0.68965987938784945,2.2757241303992108]
["glycochenodeoxycholate sulfate",0.95605665241240301,1.8601209135987635,null,"2-oxoarginine*",0.73118324157220005,2.2676062401770314]
["pyridoxal",0.44360665147561484,1.8601209135987635,null,"1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)",0.80735492205760406,2.2596373105057563]
["2-aminophenol sulfate",1.0976107966264224,1.856985199745905,null,"palmitoyl-arachidonoyl-glycerol (16:0/20:4) [2]*",1.3161457422933565,2.2596373105057563]
["3-methyl-2-oxovalerate",0.41142624572646502,1.8416375079047504,null,"gamma-glutamyl-epsilon-lysine",0.51601514700366469,2.2518119729937998]
["citraconate/glutaconate",0.63226821549951295,1.8386319977650252,null,"trigonelline (N'-methylnicotinate)",1.4802651220544629,2.2441251443275085]
["palmitoyl-linoleoyl-glycerol (16:0/18:2) [2]*",0.64154602908752378,1.8386319977650252,null,"phenyllactate (PLA)",0.44360665147561484,2.2291479883578558]
["nicotinamide",-0.68965987938784945,1.8181564120552274,null,"5-methylthioadenosine (MTA)",0.38956681176272562,2.2146701649892329]
["cerotoylcarnitine (C26)*",0.41142624572646502,1.8124792791635369,null,"kynurenine",-0.2515387669959645,2.2006594505464183]
["1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)*",0.70487196445635281,1.8096683018297086,null,"1,2,3-benzenetriol sulfate (2)",2.0461417816447205,2.1870866433571443]
["sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)*",0.28688114778816154,1.8041003475907662,null,"N-palmitoyl-sphingadienine (d18:2/16:0)*",0.2509615735332188,2.1739251972991736]
["17alpha-hydroxypregnenolone 3-sulfate",-1.2175914350726269,1.7931741239681502,null,"4-imidazoleacetate",0.43295940727610632,2.1549019599857431]
["isovalerylcarnitine (C5)",0.44360665147561484,1.790484985457369,null,"glucose",0.17632277264046289,2.1487416512809245]
["behenate (22:0)*",0.40053792958372886,1.790484985457369,null,"isoleucine",0.23878685958711648,2.1426675035687315]
["sphingomyelin (d18:2/24:1, d18:1/24:2)*",0.18903382439001684,1.790484985457369,null,"2-methylbutyrylcarnitine (C5)",0.3334237337251918,2.1426675035687315]
["glycodeoxycholate sulfate",1.0356239097307214,1.7878123955960423,null,"N-acetylproline",0.75702324650745967,2.1426675035687315]
["erythronate*",0.18903382439001684,1.785156151952302,null,"N1-Methyl-2-pyridone-5-carboxamide",-0.83650126771712052,2.1426675035687315]
["bilirubin (E,Z or Z,E)*",0.36737106564852945,1.785156151952302,null,"4-hydroxyphenylpyruvate",0.5360529002402098,2.1366771398795441]
["3-hydroxypyridine sulfate",1.2750070474998698,1.7619538968712045,null,"1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)",0.32192809488736235,2.1366771398795441]
["ribonate",0.44360665147561484,1.7544873321858501,null,"3-(3-hydroxyphenyl)propionate",1.6040713236688608,2.1307682802690238]
["etiocholanolone glucuronide",-0.51457317282975834,1.7495799976911059,null,"alpha-ketoglutarate",0.27500704749986982,2.1249387366082999]
["stearoylcholine*",-0.53533173299655579,1.7423214251308154,null,"decanoylcarnitine (C10)",-0.68965987938784945,2.1023729087095586]
["1-myristoyl-2-palmitoyl-GPC (14:0/16:0)",0.62293035092017679,1.7399286120149251,null,"dihomo-linolenoyl-choline",-0.78587519464715272,2.1023729087095586]
["lanthionine",0.65992455840237829,1.7189666327522726,null,"N-stearoyl-sphingadienine (d18:2/18:0)*",0.37851162325372983,2.1023729087095586]
["palmitoylcarnitine (C16)",0.35614381022527536,1.7055337738384071,null,"valine",0.18903382439001684,2.0915149811213505]
["propyl 4-hydroxybenzoate sulfate",0.45417589318580209,1.7011469235902934,null,"N1-methylinosine",-0.21759143507262679,2.0757207139381184]
["orotate",0.31034012061215049,1.6989700043360187,null,"gamma-glutamylmethionine",0.45417589318580209,2.0705810742857071]
["1-stearoyl-2-linoleoyl-GPC (18:0/18:2)*",0.18903382439001684,1.6946486305533763,null,"3-hydroxybutyrylcarnitine (2)",0.76553474636297703,2.0655015487564321]
["sphingomyelin (d18:1/18:1, d18:2/18:0)",0.17632277264046289,1.6903698325741012,null,"paraxanthine",2.0107798387532427,2.0655015487564321]
["gamma-glutamylglutamate",0.83995958748953181,1.6882461389442456,null,"linoleoylcarnitine (C18:2)*",-0.32192809488736229,2.0362121726544449]
["dihomo-linolenoyl-choline",-0.66657626627480826,1.6840296545430822,null,"tyramine O-sulfate",1.7612852733616193,2.0177287669604316]
["threonine",0.20163386116965043,1.6777807052660807,null,"diacylglycerol (14:0/18:1, 16:0/16:1) [2]*",1.3617683594191534,2.0132282657337552]
["1-stearoyl-GPE (18:0)",0.41142624572646502,1.6757175447023074,null,"3-hydroxy-2-ethylpropionate",0.91073266190291258,2]
["N-acetylasparagine",0.44360665147561484,1.6716203965612624,null,"N-trimethyl 5-aminovalerate",-0.15200309344504997,1.9871627752948278]
["lidocaine",1.7268312170324931,1.6716203965612624,null,"stearoylcholine*",-0.5994620704162712,1.9871627752948278]
["choline phosphate",0.28688114778816154,1.6556077263148892,null,"3-hydroxylaurate",0.61353165291792711,1.9829666607012197]
["vanillic alcohol sulfate",1.3950627995175777,1.6382721639824072,null,"1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*",0.79077203786200001,1.9665762445130504]
["1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)",0.32192809488736235,1.6363880201078558,null,"linolenate [alpha or gamma; (18:3n3 or 6)]",0.93357263826102388,1.9625735020593764]
["5-(galactosylhydroxy)-L-lysine",-0.91593573521152549,1.6270879970298935,null,"N-acetyl-3-methylhistidine*",-0.9434164716336324,1.9586073148417751]
["ectoine",1.1110313123887441,1.6252516539898962,null,"palmitoloelycholine",-0.73696559416620622,1.9244530386074692]
["N-behenoyl-sphingadienine (d18:2/22:0)*",0.27500704749986982,1.6216020990518623,null,"palmitoylcholine",-0.57776699931695219,1.9172146296835499]
["dodecanedioate",0.94110631094643149,1.6143937264016879,null,"tyrosine",0.20163386116965043,1.9136401693252518]
["1,2-dipalmitoyl-GPE (16:0/16:0)*",0.96347412397488608,1.6108339156354676,null,"glucuronate",0.2509615735332188,1.9065783148377649]
["xylose",0.96347412397488608,1.6055483191737838,null,"oleoylcholine",-0.5994620704162712,1.9065783148377649]
["eugenol sulfate",2.1731274334806563,1.5951662833800619,null,"asparagine",0.18903382439001684,1.8927900303521317]
["1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*",0.67807190511263782,1.5702477199975919,null,"1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)*",0.2509615735332188,1.8927900303521317]
["kynurenine",-0.20091269392599642,1.5686362358410126,null,"alpha-ketobutyrate",0.54596836910529256,1.8696662315049939]
["mannitol/sorbitol",0.86393845042397166,1.5451551399914898,null,"cytidine",-0.68965987938784945,1.8507808873446201]
["gamma-glutamylisoleucine*",0.5360529002402098,1.5406075122407692,null,"3-hydroxyhexanoate",0.75702324650745967,1.8356471442155629]
["3-hydroxyisobutyrate",0.50589092972995731,1.5391021572434522,null,"1-arachidonoyl-GPI (20:4)*",0.60407132366886085,1.8297382846050425]
["sphingomyelin (d18:1/24:1, d18:2/24:0)*",0.22650852980867975,1.518557371497695,null,"gluconate",0.28688114778816154,1.8297382846050425]
["suberate (octanedioate)",0.72246602447109098,1.5171264163912463,null,"glycocholate",1.4005379295837288,1.8041003475907662]
["1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)",0.62293035092017679,1.5128616245228135,null,"1,3,7-trimethylurate",1.4594316186372973,1.8013429130455774]
["2-hydroxybutyrate/2-hydroxyisobutyrate",0.40053792958372886,1.5044556624535514,null,"sucrose",1.6276068381296498,1.7878123955960423]
["1-palmitoyl-2-oleoyl-GPE (16:0/18:1)",0.60407132366886085,1.4975728800155672,null,"xylose",1.0356239097307214,1.785156151952302]
["13-methylmyristate",0.94860084749335571,1.4828041020500258,null,"ursodeoxycholate",1.8519988371124465,1.7825160557860937]
["S-methylmethionine",1.5058909297299574,1.4685210829577449,null,"2-hydroxyphenylacetate",0.51601514700366469,1.779891911959945]
["3-hydroxyoctanoate",0.44360665147561484,1.4672456210075022,null,"N-stearoyl-sphinganine (d18:0/18:0)*",0.58496250072115619,1.779891911959945]
["alpha-hydroxyisovalerate",-0.26881675842780001,1.4571745730408201,null,"N1-Methyl-4-pyridone-3-carboxamide",-0.62148837674627011,1.7721132953863266]
["hexanoylglutamine",0.85598969730848073,1.4559319556497243,null,"glycochenodeoxycholate sulfate",0.91073266190291258,1.7423214251308154]
["docosahexaenoylcholine",-0.55639334852438527,1.4485500020271249,null,"3-hydroxy-3-methylglutarate",0.35614381022527536,1.7375489102695705]
["xanthine",-0.37706964907982332,1.4436974992327127,null,"ceramide (d18:1/17:0, d17:1/18:0)*",0.42223300068304781,1.7328282715969863]
["arachidonoylcholine",-0.53533173299655579,1.4412914294668342,null,"1-stearoyl-2-oleoyl-GPE (18:0/18:1)",1.1890338243900169,1.7235381958267559]
["thioproline",0.15055967657538141,1.4294570601181025,null,"glycodeoxycholate sulfate",1.0071955014042038,1.712198270069774]
["alpha-ketobutyrate",0.45417589318580209,1.4225082001627747,null,"gamma-glutamylleucine",0.5360529002402098,1.6989700043360187]
["N-acetylleucine",0.73118324157220005,1.4134126953282451,null,"adipoylcarnitine (C6-DC)",0.68706068833989242,1.6968039425795112]
["taurine",0.18903382439001684,1.4122890349810886,null,"phosphoethanolamine",0.46466826700344421,1.6968039425795112]
["myristate (14:0)",0.71369581484335898,1.4111682744057927,null,"cystathionine",0.95605665241240301,1.6925039620867872]
["adipate",0.43295940727610632,1.4111682744057927,null,"docosahexaenoylcholine",-0.62148837674627011,1.6861327796308465]
["indolelactate",-0.26881675842780001,1.3904055907747799,null,"gamma-glutamyltyrosine",0.47508488294878265,1.6840296545430822]
["pentadecanoate (15:0)",0.54596836910529256,1.38933983691012,null,"3-hydroxyhippurate",1.5459683691052926,1.6777807052660807]
["stearoyl ethanolamide",0.32192809488736235,1.3840499483435988,null,"arachidonoylcarnitine (C20:4)",-0.30400618689009989,1.6675615400843946]
["octadecanedioate",0.5360529002402098,1.3829996588791011,null,"hippurate",1,1.6675615400843946]
["3-hydroxyhexanoate",0.62293035092017679,1.3809066693732572,null,"etiocholanolone glucuronide",-0.51457317282975834,1.6635402661514704]
["1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)*",0.34482849699744117,1.3777859770337046,null,"citrulline",-0.18442457113742744,1.6516951369518393]
["sebacate (decanedioate)",0.41142624572646502,1.3746875490383261,null,"palmitoyl-arachidonoyl-glycerol (16:0/20:4) [1]*",1.0976107966264224,1.6420651529995463]
["pregnenolone sulfate",-0.47393118833241243,1.3716110699496884,null,"uridine",-0.43440282414577491,1.6420651529995463]
["nervonoylcarnitine (C24:1)*",0.60407132366886085,1.3675427078152758,null,"beta-citrylglutamate",0.38956681176272562,1.6363880201078558]
["ceramide (d18:1/20:0, d16:1/22:0, d20:1/18:0)*",0.27500704749986982,1.3635121036466347,null,"salicylate",0.84799690655495008,1.6090648928966209]
["15-methylpalmitate",0.58496250072115619,1.3575354797578787,null,"10-heptadecenoate (17:1n7)",0.83187724119167306,1.6003262785189618]
["1-palmitoyl-2-stearoyl-GPC (16:0/18:0)",0.28688114778816154,1.3565473235138126,null,"2,3-dihydroxyisovalerate",1.207892851641333,1.5867002359187481]
["arabonate/xylonate",0.60407132366886085,1.3545777306509081,null,"linoleoyl-linoleoyl-glycerol (18:2/18:2) [1]*",-0.66657626627480826,1.5816987086802545]
["laurylcarnitine (C12)",-0.39592867633113921,1.3467874862246563,null,"methylphosphate",0.38956681176272562,1.5783960731301689]
["gamma-glutamylphenylalanine",0.54596836910529256,1.3458234581220394,null,"chenodeoxycholate",1.5058909297299574,1.575118363368933]
["malate",0.46466826700344421,1.342944147142896,null,"glycerophosphoglycerol",0.60407132366886085,1.5686362358410126]
["lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)*",0.28688114778816154,1.3400837999301498,null,"caffeine",1.5210507369009634,1.5686362358410126]
["gamma-glutamyltryptophan",0.56559717585422509,1.3391345219961308,null,"dimethylglycine",0.2509615735332188,1.5622494371796121]
["sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)*",0.23878685958711648,1.3269790928711038,null,"2-hydroxydecanoate",0.46466826700344421,1.5622494371796121]
["maleate",0.41142624572646502,1.3233063903751334,null,"isovalerylcarnitine (C5)",0.40053792958372886,1.5606673061697374]
["chenodeoxycholate",1.3334237337251917,1.3178549236261683,null,"glutarate (pentanedioate)",0.58496250072115619,1.5482135644757098]
["gamma-glutamylglutamine",0.11103131238874395,1.3160528692484879,null,"ethylmalonate",0.2509615735332188,1.5466816599529623]
["imidazole propionate",0.3334237337251918,1.3133637307377066,null,"1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)",0.97085365434048343,1.5287082889410615]
["palmitoyl sphingomyelin (d18:1/16:0)",0.15055967657538141,1.3053948010664314,null,"leucine",0.18903382439001684,1.5272435506827877]
["gamma-glutamylalanine",0.54596836910529256,1.3045183235098026,null,"sulfate*",0.32192809488736235,1.5257837359237447]
["alpha-hydroxyisocaproate",0.48542682717024171,1.3027706572402824,null,"myristoleoylcarnitine (C14:1)*",-0.51457317282975834,1.5214335044061567]
["methionine sulfone",0.12432813500220179,1.3010299956639813,null,"arachidonoylcholine",-0.55639334852438527,1.5128616245228135]
[{"$nulls":4},"choline",-0.21759143507262679,1.5114492834995557]
[{"$nulls":4},"malonate",0.29865831556451516,1.5100415205751654]
[{"$nulls":4},"imidazole lactate",0.13750352374993502,1.5016894462103996]
[{"$nulls":4},"1-palmitoyl-GPI (16:0)",0.82374936030827284,1.4989407377822486]
[{"$nulls":4},"1-methylhistidine",-0.23446525363702297,1.4921441283041692]
[{"$nulls":4},"4-ethylphenylsulfate",0.88752527074158749,1.485452247339714]
[{"$nulls":4},"N-acetylaspartate (NAA)",0.20163386116965043,1.4841261562883208]
[{"$nulls":4},"erythronate*",0.17632277264046289,1.4814860601221125]
[{"$nulls":4},"phenylacetylcarnitine",1.1699250014423124,1.4736607226101559]
[{"$nulls":4},"serine",0.17632277264046289,1.4659738939438649]
[{"$nulls":4},"propionylcarnitine (C3)",0.44360665147561484,1.4522252946121774]
[{"$nulls":4},"1-palmitoleoyl-2-linolenoyl-GPC (16:1/18:3)*",0.64154602908752378,1.4461169733561257]
[{"$nulls":4},"5-bromotryptophan",-0.26881675842780001,1.4306260903849541]
[{"$nulls":4},"(N(1) + N(8))-acetylspermidine",-0.39592867633113921,1.4294570601181025]
[{"$nulls":4},"2-hydroxyhippurate (salicylurate)",1,1.4248121550723389]
[{"$nulls":4},"docosatrienoate (22:3n6)*",0.78240856492737332,1.4202164033831899]
[{"$nulls":4},"urate",-0.21759143507262679,1.4156687756324693]
[{"$nulls":4},"adrenate (22:4n6)",0.5945485495503543,1.4067139329795428]
[{"$nulls":4},"aconitate [cis or trans]",0.3334237337251918,1.3990271043132518]
[{"$nulls":4},"pyridoxal",0.36737106564852945,1.3968556273798178]
[{"$nulls":4},"octadecanedioate",0.5360529002402098,1.3957739469155299]
[{"$nulls":4},"O-sulfo-L-tyrosine",-0.45403163089470749,1.3872161432802645]
[{"$nulls":4},"indolin-2-one",0.73118324157220005,1.3851027839668655]
[{"$nulls":4},"arabonate/xylonate",0.61353165291792711,1.3757179041643317]
[{"$nulls":4},"2-aminoadipate",0.27500704749986982,1.3746875490383261]
[{"$nulls":4},"dihydroorotate",0.17632277264046289,1.3746875490383261]
[{"$nulls":4},"N6,N6,N6-trimethyllysine",-0.39592867633113921,1.3716110699496884]
[{"$nulls":4},"2-isopropylmalate",1.1505596765753814,1.3625102704874892]
[{"$nulls":4},"cytosine",0.80735492205760406,1.3595185630295781]
[{"$nulls":4},"bilirubin (Z,Z)",-0.30400618689009989,1.344861565188618]
[{"$nulls":4},"palmitoyl-oleoyl-glycerol (16:0/18:1) [2]*",0.64154602908752378,1.342944147142896]
[{"$nulls":4},"3-hydroxybutyrylcarnitine (1)",1.7865963618908067,1.3381873144627388]
[{"$nulls":4},"4-vinylguaiacol sulfate",1.2986583155645153,1.332547047110046]