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{"sheet":"Table S6","index":0,"n_rows":79,"n_cols":7,"rows_kept":79,"cut":false,"hidden":false,"merged":[[0,0,0,2],[0,4,0,6]]}
["Significant gradient muscle metabolites before HFD",null,null,null,"Significant gradient muscle metabolites after HFD"]
["Biochemical Name","Fold Change (log2) Evening/Morning","p-value (-log10)",null,"Biochemical Name","Fold Change (log2) Evening/Morning","p-value (-log10)"]
["isovalerylcarnitine (C5)",2.176322772640463,4.9925082667046645,null,"3-hydroxybutyrate (BHBA)",1.5655971758542251,4.2765443279648139]
["sedoheptulose-7-phosphate",1.0635029423061579,4.9139962943816178,null,"cytidine",-3.8365012677171206,4.1525569082534171]
["isobutyrylcarnitine (C4)",2.22650852980868,4.6497907596900516,null,"3-hydroxyisobutyrate",1.3729520979118293,3.6989700043360187]
["2-hydroxyglutarate",0.73118324157220005,4.3569225580773505,null,"isovalerylcarnitine (C5)",1.6780719051126378,3.3979400086720375]
["3-hydroxyisobutyrate",1.5410191531335593,4.2855696431462054,null,"3-(4-hydroxyphenyl)lactate",0.74846123300403555,3.3010299956639813]
["cytidine 5'-diphosphocholine",-1.3219280948873622,3.5228787452803374,null,"lactosyl-N-palmitoyl-sphingosine (d18:1/16:0)",2.611172380044005,3.2218487496163566]
["1-stearoyl-2-linoleoyl-GPS (18:0/18:2)",2.2295879227406519,3.3979400086720375,null,"acisoga",-0.6438561897747247,3]
["1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)",0.78240856492737332,3.3979400086720375,null,"isobutyrylcarnitine (C4)",1.6088092426755241,2.8860566476931631]
["glycocholate",1.7355221772965377,3.3979400086720375,null,"lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)*",1.8032270364349277,2.7212463990471711]
["cytidine",-3.3219280948873622,3.3979400086720375,null,"caffeine",2.1890338243900169,2.2006594505464183]
["2-methylbutyrylcarnitine (C5)",0.99276843076892418,3.1549019599857431,null,"glycine",-0.32192809488736229,2.0132282657337552]
["glutamate",-0.62148837674627011,3.0457574905606752,null,"beta-citrylglutamate",-0.47393118833241243,1.9355420107730816]
["1-stearoyl-2-oleoyl-GPS (18:0/18:1)",3.3936907641874536,2.9586073148417751,null,"2-hydroxybutyrate/2-hydroxyisobutyrate",0.5360529002402098,1.9318141382538383]
["lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)*",1.9030382701129123,2.9586073148417751,null,"sulfate*",1.3673710656485296,1.8696662315049939]
["fructose",0.69599381310990016,2.8239087409443187,null,"glycochenodeoxycholate",1.4168397419128294,1.832682665251824]
["1-stearoyl-2-arachidonoyl-GPS (18:0/20:4)",2.7070829917717063,2.795880017344075,null,"oleoyl-linolenoyl-glycerol (18:1/18:3) [2]*",-0.86249647625006509,1.8210230527068305]
["glycosyl-N-stearoyl-sphingosine (d18:1/18:0)",2.3190398155625362,2.7695510786217259,null,"cytidine 5'-diphosphocholine",-0.83650126771712052,1.790484985457369]
["lactosyl-N-palmitoyl-sphingosine (d18:1/16:0)",2.3504972470841334,2.744727494896694,null,"stearoyl-linoleoyl-glycerol (18:0/18:2) [2]*",0.82374936030827284,1.7258421507363202]
["phenyllactate (PLA)",0.87184364850931773,2.7212463990471711,null,"1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)",0.52606881166758768,1.645891560852599]
["proline",0.3334237337251918,2.6777807052660809,null,"3-methylglutaconate",0.99276843076892418,1.6420651529995463]
["glycochenodeoxycholate",1.8114710305298358,2.6382721639824069,null,"pyrraline",0.67807190511263782,1.6143937264016879]
["nicotinamide",-0.23446525363702297,2.5086383061657274,null,"N-acetylasparagine",-0.30400618689009989,1.563837352959244]
["N-acetylasparagine",-0.41503749927884381,2.4559319556497243,null,"3-hydroxybutyrylcarnitine (1)",0.72246602447109098,1.5575202309355514]
["1-stearoyl-2-oleoyl-GPE (18:0/18:1)",0.70487196445635281,2.3767507096020997,null,"maltose",0.73984810269932755,1.5406075122407692]
["1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)",0.66902676550963081,2.3665315444204134,null,"1-palmitoleoylglycerol (16:1)*",-0.55639334852438527,1.5406075122407692]
["1-oleoyl-2-arachidonoyl-GPI (18:1/20:4) *",0.95605665241240301,2.3467874862246565,null,"1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)",0.15055967657538141,1.5272435506827877]
["cytidine 5'-monophospho-N-acetylneuraminic acid",-0.68965987938784945,2.3098039199714862,null,"methionine sulfoxide",0.22650852980867975,1.5199930570428493]
["acisoga",-0.53533173299655579,2.2365720064370627,null,"lidocaine",-1.6438561897747248,1.4723700991286615]
["1-oleoylglycerol (18:1)",-0.5994620704162712,2.1191864077192086,null,"pseudouridine",-0.18442457113742744,1.4647058799572295]
["1-palmitoyl-2-oleoyl-GPG (16:0/18:1)",1.6690267655096309,2.0757207139381184,null,"sphingadienine",-0.43440282414577491,1.4225082001627747]
["1-(1-enyl-stearoyl)-GPE (P-18:0)*",0.55581615506163962,2.0604807473813813,null,"6-phosphogluconate",0.87970576628228825,1.4168012260313771]
["glycodeoxycholate",1.8073549220576042,2.0177287669604316,null,"N1-Methyl-4-pyridone-3-carboxamide",-0.55639334852438527,1.4034029043735399]
["1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)*",1.0496307677246004,2.0132282657337552,null,"4-methyl-2-oxopentanoate",0.63226821549951295,1.3957739469155299]
["sphingadienine",-0.53533173299655579,1.9913998282380825,null,"2-methylbutyrylcarnitine (C5)",0.56559717585422509,1.3615107430453628]
["2-hydroxybutyrate/2-hydroxyisobutyrate",0.54596836910529256,1.9746941347352298,null,"choline phosphate",-0.45403163089470749,1.3605135107314139]
["acetyl CoA",-0.68965987938784945,1.9393021596463884,null,"propionylcarnitine (C3)",0.37851162325372983,1.3575354797578787]
["galactonate",-0.5994620704162712,1.9281179926938745,null,"S-adenosylmethionine (SAM)",0.71369581484335898,1.344861565188618]
["methylmalonate (MMA)",-0.78587519464715272,1.8996294548824371]
["tiglylcarnitine (C5:1-DC)",0.82374936030827284,1.7721132953863266]
["sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)",0.27500704749986982,1.7471469690201069]
["ceramide (d18:1/20:0, d16:1/22:0, d20:1/18:0)*",-0.34007544159762171,1.744727494896694]
["1,2-dipalmitoyl-GPE (16:0/16:0)*",0.97819562968165163,1.7304870557820837]
["N-methylproline",1.1176950426697545,1.7258421507363202]
["butyrylcarnitine (C4)",-0.57776699931695219,1.7212463990471711]
["coenzyme A",-1.3959286763311392,1.7033348097384688]
["1-palmitoyl-2-stearoyl-GPC (16:0/18:0)",0.44360665147561484,1.6968039425795112]
["dimethylglycine",0.21412480535284734,1.645891560852599]
["maleate",-0.34007544159762171,1.645891560852599]
["palmitoleate (16:1n7)",-0.35845397091247633,1.6439741428068773]
["1-(1-enyl-oleoyl)-GPE (P-18:1)*",0.50589092972995731,1.6363880201078558]
["1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*",0.69599381310990016,1.6108339156354676]
["cytidine-5'-diphosphoethanolamine",-0.68965987938784945,1.6055483191737838]
["succinate",-0.30400618689009989,1.6038006529042637]
["ethylmalonate",-0.43440282414577491,1.5951662833800619]
["valylglycine",-0.47393118833241243,1.5800442515102422]
["linolenate [alpha or gamma; (18:3n3 or 6)]",-0.47393118833241243,1.5734887386354248]
["alanylleucine",1.0840642647884746,1.5686362358410126]
["pyruvate",0.42223300068304781,1.5361070110140926]
["10-heptadecenoate (17:1n7)",-0.35845397091247633,1.5331323796458904]
["thioproline",0.87970576628228825,1.5331323796458904]
["3-hydroxybutyrylcarnitine (2)",-0.53533173299655579,1.5171264163912463]
["3-(4-hydroxyphenyl)lactate",0.44360665147561484,1.5072396109731625]
["glycylvaline",0.63226821549951295,1.5044556624535514]
["UDP-glucuronate",0.87970576628228825,1.5030703519267852]
["N-palmitoyl-sphinganine (d18:0/16:0)",1.1890338243900169,1.494850021680094]
["1-stearoyl-GPE (18:0)",0.47508488294878265,1.4762535331884354]
["cysteine",0.52606881166758768,1.4634415574284698]
["1-(1-enyl-palmitoyl)-GPE (P-16:0)*",0.42223300068304781,1.4111682744057927]
["N-stearoyl-sphingosine (d18:1/18:0)*",-0.39592867633113921,1.3809066693732572]
["stearate (18:0)",0.21412480535284734,1.3746875490383261]
["pyrraline",0.61353165291792711,1.3746875490383261]
["maltose",0.68706068833989242,1.3635121036466347]
["6-phosphogluconate",0.85598969730848073,1.3545777306509081]
["1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1)*",0.29865831556451516,1.3506651412878581]
["1-arachidonoyl-GPI (20:4)*",0.61353165291792711,1.3467874862246563]
["S-adenosylmethionine (SAM)",0.71369581484335898,1.3400837999301498]
["hexadecadienoate (16:2n6)",-0.45403163089470749,1.3169529617611504]