Name SampleType AnimalID Treatment Time AnatomicalRegion Concentration PreAmp Actb Adamts13 ALDH2 ALDH7a1 ANG1 Arg1 Bambi BMP6 CASP3 CCL3 Cdkn1a CH25H Clcn3 Col14a1 Col3a1 Col4a1 COL4A2 Csf1 Csrp2 Cxcl12 CYP1A2 CYP27B1 CYP2E1 Ecm1 Erlin2 Fap Fn1 Gapdh GFAP Got1 HGFa.b HIF1A IGF1 IL1R1 IRF1 Itgad KLF6 Kras LAMA1 Lep Lrat Mapk1 MMP13 MMP14 MMP2 Mmp3 Mrc1 Nfkb2 Npy PDGFA Pklr Ppara Rara Rbp1 rbp2 RDH10 Serpine1 SMAD1 Smad4 SMAD7 Socs3 Spp1 STAT3 TGFb1 TgfbRII TIMP2 TLR9 Tnf TNFR1 UBQLN1 Vegfa Vim SH1-1L-1S-P4 1 Cell HSC 1 Control 0h Portal NA 1 4.591476338 NA NA NA 0.0571084400000004 1.808922315 -0.25814315 0.672453805 NA 1.391590755 -1.32754715 0.947236725 1.41999875 0 0.565157650000002 0.0423010449999994 0.357854261999999 NA -0.532843710000001 0.0930022499999996 NA NA NA NA 2.19502568 0.218434991999999 0.338160822500001 1.296102451 0.22859534 2.09791313 NA NA 1.081124998 NA NA -4.53938537 NA -0.777878590000002 NA 0 0.0307635040000003 0.0891985199999992 0 0.55052295 1.998376175 0.703301389999999 1.74050948 NA -1.3506030455 NA NA 1.95281218 1.80056014 NA NA NA -2.943596697 NA -0.383951475 NA NA 1.01287522 -0.314198190000001 NA 4.498708333 0.87033576 NA 0.0212748549999988 NA 0.458809729999999 NA 2.04524625 SH1-1L-1S-C2 1 Cell HSC 1 Control 0h Central NA 1 4.536463523 0.36091425 NA NA -3.62031968 3.847820897 6.29932388 0.947796745 NA -0.224854485 NA 0 4.16975059 NA 3.60768943 0.264074675000001 0.0131933850000001 0.0986294749999992 NA 0.872283829999999 NA NA NA NA 3.7287948 -0.89114182 -0.1748237975 1.183057034 -1.0414168 2.85155142 NA NA 1.300432755 NA NA NA NA 1.8329994 NA 5.48445113 -0.148794214 3.90077082 -0.22061869 0.72947069 1.352758615 0.933120089999998 0 NA -1.1030553155 NA NA 1.67592165 2.64312514 NA NA NA -2.88346099 NA -3.963049065 NA NA 0.469151490000001 0.7493701 NA 3.33475689 -0.236735100000001 NA 0.095353564999999 NA 1.60745748 NA 0.26369341 SH1-2L-1S-P1 1 Cell HSC 2 Ethanol 0h Portal NA 1 0.275786245 NA NA NA 2.1919613 -3.356721685 NA -1.445717725 NA -0.394925635000002 NA -0.29182834 -4.69436832 NA -1.23539019 0.420120435 -0.0131933850000001 NA -2.71000459 0.28257056 NA NA NA NA 0 -0.179245940000001 -5.8402975275 0.792524178 0 -4.7510088 NA NA -6.186980025 NA NA 0.25105582 NA -3.25521422 NA NA -0.500793254 NA 0.66900652 0.0227872899999992 2.410423605 0.864279939999999 -3.71059761 NA 0.605573904499999 NA NA -5.47879221 -2.21592554 NA NA NA -0.641186180000001 NA 0.122727565 NA NA -0.63393942 NA NA 1.39953569 0.840771589999999 NA 0.0238020549999982 NA -4.68367341 NA -1.27325831 SH1-2L-1S-P4 1 Cell HSC 2 Ethanol 0h Portal NA 1 NA NA NA NA NA 1.079396515 NA NA NA NA 0 NA 1.13091711 NA NA NA 0.0404330750000002 NA 0.532843710000001 NA NA NA NA NA -1.47871054 0.0662491000000003 0.809062922500001 -1.310405209 NA NA NA NA NA NA NA 0.468473609999999 NA -4.37875357 NA NA NA NA NA -0.0227872899999992 -0.796453934999997 -1.26630399 NA NA -1.2806280955 NA NA -3.86575545 -1.23263983 NA NA NA -0.659309169999999 NA NA NA NA -5.26498745 0.314198190000001 NA -3.15029553 0 NA 0.00770480500000037 NA 0 NA NA SH1-2L-1S-P5 1 Cell HSC 2 Ethanol 0h Portal NA 1 -1.289864815 NA NA NA 0.536166390000002 -7.700275825 NA NA NA 2.357404275 NA 0.308414689999999 -2.53028193 NA NA -0.273128424999999 -0.403282065 NA 4.18023062 -0.6101844 NA NA NA NA NA 0 NA 0 0.931194380000001 NA NA NA NA NA NA NA NA -3.24314772 NA NA 2.630117245 NA -2.38554232 -0.85487042 0.235564425 0.561693339999999 NA NA 2.3758273865 NA NA NA 0.14936045 NA NA NA 1.726605153 NA NA NA NA 2.58081948 NA NA 2.98114387 -0.22856234 NA -0.315260275000001 NA NA NA 0 SH1-2L-1S-C1 1 Cell HSC 2 Ethanol 0h Central NA 1 -1.659909515 0 NA NA -4.32353188 NA 6.96229775 0.752925485 NA 0.703752735 3.90507438 -0.23169497 3.4034627 NA -3.06333077 -0.0423010449999994 0.0404330750000002 -0.0986294749999992 -8.30526232 -0.30839829 NA NA NA NA -3.66369433 0.35098092 NA 0.0379722250000007 -1.09947122 NA NA NA NA NA NA NA NA 2.08215948 NA 6.04926737 -0.0307635040000003 NA 0.49233839 0.673612000000001 -1.009103055 0.130312709999999 NA NA 0.133256905500001 NA NA -7.60452594 1.65323615 NA NA NA -0.546395806999999 NA NA NA NA 0.24595939 -3.88027399 NA -7.13102075 0.702663620000001 NA 1.144964185 NA NA NA NA SH1-2L-1S-C2 1 Cell HSC 2 Ethanol 0h Central NA 1 NA NA NA NA NA NA NA 0.360712484999999 NA NA NA -0.77703767 NA NA 0 -2.028741885 -0.942752415 NA 1.26631294 -0.0549120900000002 NA NA NA NA NA 0 NA -0.0868722680000005 -3.22901413 NA NA NA -0.758193615000001 NA NA NA NA NA NA -0.767522139999999 -1.122304284 NA 0.432673340000001 -1.43608309 -0.917388984999999 0.63657384 NA NA 1.2530116045 NA NA -0.542101630000001 NA NA NA NA -0.17602631 NA NA NA NA 1.05352095 NA NA NA NA NA -1.039787435 NA NA NA NA SH1-2L-1S-C3 1 Cell HSC 2 Ethanol 0h Central NA 1 2.064996775 NA NA NA -1.11796516 NA NA -0.360712484999999 NA 0.224854485 NA 0.56969207 NA NA 0.0785830300000026 -0.634024435 -1.565751925 NA 2.83785073 0.0549120900000002 NA NA NA NA -2.42576251 -0.49304152 NA 0.674044895 0.94525149 0 NA NA NA NA NA NA NA 0.217025529999999 NA NA 2.067942576 NA -0.303653429999999 0.0565845700000009 2.526899625 1.1692717 NA NA 2.6396042945 NA NA 1.31846838 -0.77791131 NA NA NA 1.624781547 NA -0.0139579049999998 NA NA 1.01287522 NA NA 2.71605167 1.43965336 NA -0.00770480500000037 NA 1.92971394 NA NA SH1-2L-1S-C4 1 Cell HSC 2 Ethanol 0h Central NA 1 1.970611725 -5.76367514 NA NA -0.124540159999999 NA 0 -1.362225995 NA -1.385496475 2.79853607 -0.54777801 -1.13091711 2.2583717 0.882534340000003 0.157047045 0.0404330750000002 NA -2.39789878 0.98083666 NA NA NA NA -2.24084203 -1.08812792 -6.1056613075 -0.241836730999999 -1.39979363 NA NA NA -8.228729365 NA NA -1.75681944 NA -1.31199607 NA -2.17656456 1.081168986 NA -0.11441574 -1.18072631 -2.616629885 -0.906008050000001 NA NA 1.9386988465 NA NA 0 -0.14936045 NA NA NA 2.396082822 NA 0.527794374999999 NA NA 0.13076613 NA NA -0.813060610000001 -0.15021709 NA -0.602770375000001 NA -0.879734540000001 NA 1.71120582 SH1-2L-1S-C5 1 Cell HSC 2 Ethanol 0h Central NA 1 -2.319777465 NA NA NA -1.54498732 NA -1.0168158 -0.779931305 NA -0.788820135000002 -0.873063669999999 0.89231451 -4.27328284 NA NA 0.0900772850000022 -1.285270465 NA 0.87120658 -0.220077059999999 NA NA NA NA -1.31783662 0 NA 0.422682788000001 0.0727062700000012 -2.27281581 NA NA NA NA NA -0.985089389999998 NA 0.155761479999999 NA NA 0.432074256000001 NA 0.669506770000002 0.605565810000001 -0.235564425 -0.130312709999999 NA NA 0.161715994500001 NA NA 0.72147565 0.33246536 NA NA NA 1.042181426 NA NA NA NA -0.211697719999999 NA NA 0 0.1925519 NA 0.953111765 NA NA NA NA SH1-2l-1S-P-5 1 Cell HSC 2 Ethanol 0h Portal NA 2 -0.844755853000001 2.87985802175 -1.663818 -1.4444036965 NA -10.451552675 0.63976619 0.419148269999997 NA NA NA -0.700900795000002 -0.192386425000002 NA NA 0.136965742499999 0.431949529999999 1.58779297 0.13145104 -0.8664235175 -0.943181737000002 0.0586286749999996 0.799275655249998 NA NA -0.4223962875 NA 0.488076394999998 -0.12237993 NA NA NA NA NA NA NA NA NA 1.09586904 0.826892462499999 0.946210274999999 0.286451304999998 0.397645699999998 -0.504860315000001 1.43107618 -1.72320972 3.55240603675 NA 1.3613949 -3.00774187 -0.0351415325 NA -0.233762950000003 NA NA 1.5850434675 1.032569085 0.492556627499998 NA 0.195105839999998 -0.0763070400000014 -0.0353137600000011 0.172236102499999 NA 0.824308389249999 -0.0609170325000017 -0.925991455 NA NA -0.640691510000002 NA NA SH1-2l-1S-P-6 1 Cell HSC 2 Ethanol 0h Portal NA 2 -3.453630188 -2.37287863325 -1.561470825 -3.0389961915 -2.44580346 -2.41960566 0.642084325000001 0.354728535 -0.863711801999999 -3.23571627 NA 0.69068812 0 NA NA -0.247744122499999 0.235497945000001 -1.811072255 NA 0.284454567500002 -1.427481972 0.863879130000001 -0.0965935437499996 NA NA -0.322359552499998 NA -0.198520332 -0.636761164999998 -1.632865205 -2.93179394 NA NA NA -1.9045271775 -3.34530088 NA -6.790723025 0.0711483950000016 -0.7886780225 -0.23987913 -5.9131437 -0.102355514999999 -0.76251442 -1.243439915 -0.0748547849999994 -0.45676352825 -4.088265236 0.180752755 -2.555536585 2.0635065625 NA -0.135175655000001 NA NA -6.7579182575 -0.745368300000001 -0.342876707499999 1.217154825 -0.155653125000001 0.123257195000001 -0.0624407949999988 NA NA -2.37958290575 -0.0304350074999986 -0.137277279999999 NA NA -0.934526974999999 0.87749406 NA SH1-2l-1S-C-4 1 Cell HSC 2 Ethanol 0h Central NA 2 -1.536517523 2.33729007175 0.0930728300000014 0.6039443835 -0.393243925 -0.333059894999998 0.153228560000001 0.185443659999999 NA -1.290283365 NA 0.887498605 0.836468365 1.4955655875 NA 0.0126992025000003 -0.0994812399999994 -1.50409549 NA 0.240172312500001 -0.870332887 -1.217448485 -1.55486295475 -0.24983121 NA -0.0558222474999983 -4.06816171 0 0.571268930000001 -0.0960411099999998 -1.071748615 -0.215834219999998 NA -0.777423680000002 NA NA -3.82593666175 NA 0.83537508 0.245288402500001 0.433575755 0.909160575 0.46646531 0.307528835 -1.05022898 0.43810723 0.100642776750001 NA -0.266300409999999 -0.67498198 2.7511507075 0.310086194999998 -1.47787388 NA NA 0.5136431975 0.148923654999999 0.0735396375000006 0.793807179999999 -0.42945939 0.229743899999999 -0.1685231 -1.4518967775 NA 0.720261019250001 0.5271286175 -1.092273755 NA NA -0.94529545 0.0229252849999995 0.324983250000001 SH1-2l-1S-C-6 1 Cell HSC 2 Ethanol 0h Central NA 2 -3.012518323 1.40258231175 -0.07698099 -0.2239455965 NA NA 0.207583349999998 -0.441896950000002 NA -1.213008505 -0.1051587635 0.361501694999999 0.574295634999999 NA NA -0.636690977500001 -1.12753192 -0.204218840000001 3.83452957 -2.2874076075 -1.534863827 -0.702694145000001 NA NA NA -0.457710047499999 NA -0.964771039000001 -0.700134510000001 0.005416069999999 1.149970655 NA NA 0.578894189999998 NA NA NA -3.09715515 0 0.562829412499998 1.951795015 NA 0.112168539999999 -1.169943385 0.0721272500000012 -0.29728274 NA -2.569870221 7.994281207 0 2.4672016175 -0.186197155000002 NA NA NA NA 7.805438218 0.7313319675 NA -1.09745072 -1.02087852 2.03175966 -3.3589172975 NA -1.22304836075 -2.3525971425 0.169835585 NA NA NA -1.419657295 NA SH1-2p-1S-P-3 1 Cell HSC 2 Ethanol 24h Portal NA 2 0.879447526999999 NA -2.57562552 0.8436711635 NA 1.242802725 -1.8150377 -0.650254810000002 NA 0.757483565000001 2.2410183665 1.215192375 NA -3.9427773925 NA -0.3688551675 -0.92039479 NA 0.615576050000001 0.119130772500001 0.546225013000001 0.390557015000001 -0.49135309475 -2.96695421 0.587168950000001 -1.1082867575 0 -0.209958071 -0.177259689999999 NA -0.354723205 0.167009090000002 -0.179719434999999 NA -0.0347898224999996 NA -0.685249321749998 NA -5.7828773 NA 0.455280844999999 NA 1.05068706 -0.342652465 -2.58910967 0.976217160000001 NA NA 0.817888140000001 NA NA -0.944010345000001 -0.402469160000003 NA NA 0.188246947500001 1.233479785 -1.6114053925 -0.0315903300000011 -1.35184436 -2.71494751 -0.61557105 -0.312324967499999 NA NA -0.769491012500001 0.396594035000001 NA NA 0.8155684 -1.614086945 NA SH1-2p-1S-P-4 1 Cell HSC 2 Ethanol 24h Portal NA 2 0.00545008300000038 -3.98191738825 -1.36773834 -0.683329836499999 -2.416625695 1.13005347 -0.302174559999999 -0.29837275 NA -1.704202025 0.510872816500001 -0.152314934999999 -0.646732755 NA NA -0.357353987499998 -0.203852629999998 -1.8297822 -0.596205469999997 0.292464672500002 0.200003780000001 0.250320425000002 -1.21921157775 -4.08377609 -0.922925859999998 -0.427008957499998 -0.405132099999999 -0.499640756999999 -0.644721429999998 -2.72768601 -0.398224234999998 -0.624469909999997 NA NA 0.487906027500002 NA 1.26666717825 -0.84670088 -0.0489566599999982 0.253300442500001 -0.267874145 NA 0.389109100000001 0.202958345 -0.278314029999997 0.205826380000001 NA -1.707366501 -0.389449549999998 NA -1.8280220225 -1.796254705 0.0860590099999996 NA NA NA -0.751097775 0.592145017500001 -2.25012108 -0.419721189999999 0.19802404 0.191459970000002 -0.761622297499997 NA -0.704385000749999 -0.258590382499999 0.0462890450000017 NA NA -1.27794232 -0.0229252849999995 -2.5194985 SH1-2p-1S-P-5 1 Cell HSC 2 Ethanol 24h Portal NA 2 -0.482066293000002 -3.24340861825 -0.30096561 -1.0680827265 NA 0.0659295950000001 -1.46271539 0.127662649999998 NA NA -0.130987023500001 -1.045644155 -2.917362705 NA NA 0.178852022499999 -0.479128769999999 -2.71904168 -0.701335650000001 0.0201995525000003 0.786728003 0.549686935 0.71511166225 NA NA -0.1185626975 -1.39568622 -0.600620937000001 -0.809352589999999 -1.74723654 0.0787231149999998 0 -0.0318929350000001 NA NA NA NA NA 0.43689296 -2.2409684675 -0.599842115000001 NA -0.136243590000001 -0.0973971250000014 -1.23153683 0.0456261799999993 NA NA 0.458761389999999 NA -2.0070591125 NA -0.724707760000003 NA NA 1.6898661275 0.626687644999999 -0.119363062500001 NA -0.0073313300000013 -0.049224360000002 -0.736189450000001 -0.211890707499998 NA -1.91551536075 -1.4961449125 0.427318955 NA NA NA -2.438769325 NA SH1-2p-1S-C-4 1 Cell HSC 2 Ethanol 24h Central NA 2 1.1551658475 0.0206247182500006 0.936392266500001 0 -2.9400109785 0.9828708405 0.189429846499999 0.499296176499998 -0.6207502505 0.856079291499999 0.544858082999999 -0.517620248500001 0.409505021499999 -0.458974906000002 2.341457318 1.559509037 0.5380204725 -0.392911813500001 -0.6228552835 -0.186569590999999 0.9981792695 0.4774041315 0.0965935437499996 0.634746606499998 -0.4933209135 -0.164547803 -0.137885863500001 0.9789695515 0.0385079465000002 -0.0902595734999991 0.431727081499999 0.0339793865000004 0.510113071499999 NA -0.288938536000001 NA -0.0899822252500009 3.6223710665 0.322304969499999 0.307058478999999 0.0149412224999992 0.2837467815 0.3178460045 0.311781701499998 0.129251826500003 0.4499178005 -0.100642776750001 0.286175625499999 -0.273813023500001 -5.7316990835 -1.875375956 -0.0714097785000014 0.356277186499998 -0.561299462500001 NA -0.793443926 -1.6442703685 0.813350343999999 -0.669858993500001 0.415040256499999 0.536420607499998 -0.414420983500001 -0.539439620999998 0.3068980965 0.31619679575 0.30100214 0.1453646785 NA NA 0.4680352465 0.0379962114999994 1.5430957365 SH1-2p-1S-C-5 1 Cell HSC 2 Ethanol 24h Central NA 2 0.852973751999998 0.288648846750001 -0.0454099650000002 -0.178462661500001 -1.94647866 -0.207033770000001 0.156097644999999 0.0836706949999986 -1.059666012 -0.11588944 0.766197451499998 -0.428717590000001 0.555188049999998 -2.4895678575 -1.1450730625 -0.0126992025000003 -0.137508085 -0.915713855000002 0.266551065 -0.0201995525000003 2.012154629 0.498767449999999 0.130478029249999 0.994721654999998 -1.738732125 0.0181131575000002 -0.509486225000002 0.635392745999998 0.973626394999999 -0.684642025 -0.570311780000002 -1.164793575 -0.99149813 NA 0.326622742499999 NA -1.17719766675 0.0174169849999988 0.231510184999999 -0.0185142525000002 -0.662862300000002 -2.65402045 0.257164614999999 0.423866629999998 -0.0642078650000002 -0.0217937450000001 -3.05814148825 0.815908233999999 0.266067345 -2.682556515 -1.8575216575 -1.72225948 0.120335974999996 -2.882381454 NA 0.827584542499999 -0.756221285000002 0.708101172499998 -0.332035755000002 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