gene_id	gene_name	transcript_id	GO	KEGG	KO_ENTRY	EC	Description	FPKM.LN_D1	FPKM.LN_D2	FPKM.LN_D3	FPKM.LN_C1	FPKM.LN_C2	FPKM.LN_C3	fc	log2(fc)	pval	qval	regulation	significant
ENSG00000107968	MAP3K8	ENST00000263056;ENST00000542547;ENST00000415139;ENST00000375322;ENST00000413724;ENST00000375321;ENST00000430603	"GO:0000165(MAPK cascade);GO:0000186(activation of MAPKK activity);GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0023014(signal transduction by protein phosphorylation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0031295(T cell costimulation);GO:0032147(activation of protein kinase activity);GO:0042981(regulation of apoptotic process)"	04010(MAPK signaling pathway);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway)	NA	NA	mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:HGNC:6860]	1.59	0.7	1.49	0.09	0.11	0.41	2.27	1.18	0.01	0.2	up	yes
ENSG00000181690	PLAG1	ENST00000316981;ENST00000522009;ENST00000423799;ENST00000429357;ENST00000519027	GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0022612(gland morphogenesis);GO:0035264(multicellular organism growth);GO:0035265(organ growth);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0060252(positive regulation of glial cell proliferation);GO:0060736(prostate gland growth)	NA	NA	NA	pleiomorphic adenoma gene 1 [Source:HGNC Symbol;Acc:HGNC:9045]	1.43	1.8	1.47	0.11	0.29	0.03	2.13	1.09	0	0.19	up	yes
ENSG00000197937	ZNF347	ENST00000601804;ENST00000334197;ENST00000452676;ENST00000601469;ENST00000595967;ENST00000595710;ENST00000599096	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 347 [Source:HGNC Symbol;Acc:HGNC:16447]	0.06	0.32	0.18	1.43	1.29	0.61	0.48	-1.06	0.01	0.22	down	yes
ENSG00000248461	CTD-2207A17.1	ENST00000508853	NA	NA	NA	NA	NA	0.05	0.04	0.34	1.62	1.41	0.94	0.45	-1.14	0.02	0.25	down	yes
MSTRG.10023	GLYR1	MSTRG.10023.1;MSTRG.10023.2;MSTRG.10023.3;ENST00000589389;ENST00000588732;ENST00000436648;MSTRG.10023.4;ENST00000321919;MSTRG.10023.9;ENST00000587936;ENST00000591451;ENST00000591846;ENST00000588297;ENST00000586095;ENST00000587297;ENST00000586901;ENST00000587875;ENST00000591159	GO:0003677(DNA binding);GO:0004616(phosphogluconate dehydrogenase (decarboxylating) activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0035064(methylated histone binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process)	NA	NA	NA	glyoxylate reductase 1 homolog (Arabidopsis) [Source:HGNC Symbol;Acc:HGNC:24434]	4.77	6.29	8.03	14.82	13.56	9.54	0.45	-1.17	0.02	0.27	down	yes
MSTRG.10069	RMI2	ENST00000573910;ENST00000572173;ENST00000572992;ENST00000312499;ENST00000576027	GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006260(DNA replication)	NA	NA	NA	RecQ mediated genome instability 2 [Source:HGNC Symbol;Acc:HGNC:28349]	0.83	1.53	0.41	5.65	5.99	7.73	0.25	-2.03	0.01	0.24	down	yes
MSTRG.10199	TMC7	ENST00000569532;ENST00000304381;ENST00000568469;ENST00000421369;ENST00000561963	GO:0006811(ion transport);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane channel-like 7 [Source:HGNC Symbol;Acc:HGNC:23000]	2.73	2.34	2.59	0.52	0.49	0.57	2.43	1.28	0	0.08	up	yes
MSTRG.10233	TMEM159	ENST00000573487;ENST00000233047;MSTRG.10233.3;MSTRG.10233.4;ENST00000572258;ENST00000574092;ENST00000261388;ENST00000451578;ENST00000572599;ENST00000573688	GO:0005515(protein binding);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 159 [Source:HGNC Symbol;Acc:HGNC:30136]	13.16	12.85	11.89	1.77	0.8	2.15	5.54	2.47	0.01	0.2	up	yes
MSTRG.10235	SMG1P3	ENST00000542817;MSTRG.10235.2;MSTRG.10235.4;MSTRG.10235.3;ENST00000504841;ENST00000419180;ENST00000448012;ENST00000542953;MSTRG.10235.8;ENST00000519305;ENST00000521589;ENST00000534903;ENST00000545358;ENST00000535190;ENST00000537983;ENST00000543368;ENST00000544154;MSTRG.10235.19;ENST00000520823;ENST00000522480;ENST00000440195;MSTRG.10235.23;ENST00000522841;ENST00000437413	NA	NA	NA	NA	NA	3.6	3.04	3.4	1.12	1.01	0.74	2.22	1.15	0	0.18	up	yes
MSTRG.1026	NDC1	ENST00000371429;MSTRG.1026.2;ENST00000480952	GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0007129(synapsis);GO:0007283(spermatogenesis);GO:0015031(protein transport);GO:0016020(membrane);GO:0017056(structural constituent of nuclear pore);GO:0031081(nuclear pore distribution);GO:0031965(nuclear membrane);GO:0051028(mRNA transport);GO:0051292(nuclear pore complex assembly)	03013(RNA transport)	NA	NA	NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525]	7.28	10.23	7.65	25.08	22.18	11	0.36	-1.47	0.03	0.28	down	yes
MSTRG.10297	GTF3C1	ENST00000561623;ENST00000564747;ENST00000356183;ENST00000569653;ENST00000562609;ENST00000567843;ENST00000571886;ENST00000569394;ENST00000564664;ENST00000566779;ENST00000568569;ENST00000570129	"GO:0000127(transcription factor TFIIIC complex);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006383(transcription from RNA polymerase III promoter);GO:0009303(rRNA transcription);GO:0009304(tRNA transcription);GO:0010467(gene expression);GO:0016020(membrane);GO:0030529(ribonucleoprotein complex);GO:0042791(5S class rRNA transcription from RNA polymerase III type 1 promoter);GO:0042797(tRNA transcription from RNA polymerase III promoter)"	NA	NA	NA	"general transcription factor IIIC, polypeptide 1, alpha 220kDa [Source:HGNC Symbol;Acc:HGNC:4664]"	3.76	4.8	5.56	10.7	9.36	11.43	0.46	-1.12	0.01	0.23	down	yes
MSTRG.10313	NUPR1	ENST00000324873;ENST00000567646;ENST00000395641	"GO:0002526(acute inflammatory response);GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0006473(protein acetylation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0016049(cell growth);GO:0031401(positive regulation of protein modification process);GO:0035914(skeletal muscle cell differentiation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043065(positive regulation of apoptotic process);GO:0045786(negative regulation of cell cycle);GO:0048147(negative regulation of fibroblast proliferation);GO:2000194(regulation of female gonad development)"	NA	NA	NA	"nuclear protein, transcriptional regulator, 1 [Source:HGNC Symbol;Acc:HGNC:29990]"	7.62	6.83	8.39	0.05	0.01	0.03	8.52	3.09	0	0.08	up	yes
MSTRG.10323	ATXN2L	ENST00000563314;ENST00000340394;ENST00000325215;ENST00000336783;ENST00000382686;ENST00000395547;ENST00000564304;ENST00000570200;ENST00000562867;MSTRG.10323.10;MSTRG.10323.11;MSTRG.10323.12;MSTRG.10323.13;MSTRG.10323.14;MSTRG.10323.21;MSTRG.10323.22;MSTRG.10323.15;MSTRG.10323.16;MSTRG.10323.17;MSTRG.10323.18;MSTRG.10323.19;MSTRG.10323.20;MSTRG.10323.23;MSTRG.10323.24;MSTRG.10323.25;MSTRG.10323.26;MSTRG.10323.27;ENST00000568266;ENST00000564656;ENST00000561539;ENST00000566080;ENST00000565971;ENST00000570284;ENST00000564284;MSTRG.10323.35;ENST00000565845;ENST00000564035;ENST00000566946;ENST00000562583;ENST00000561732;ENST00000562686;ENST00000569318;ENST00000566007;ENST00000564162;ENST00000567024	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0010494(cytoplasmic stress granule);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0034063(stress granule assembly);GO:0044822(poly(A) RNA binding)	NA	NA	NA	ataxin 2-like [Source:HGNC Symbol;Acc:HGNC:31326]	58.82	53.29	43.44	15.96	16.89	12.71	3.25	1.7	0.01	0.2	up	yes
MSTRG.10328	NFATC2IP	ENST00000564978;ENST00000320805;ENST00000565919;MSTRG.10328.4;ENST00000565752;ENST00000562977;ENST00000568998;ENST00000568148	GO:0001816(cytokine production);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)	NA	NA	NA	"nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:25906]"	2.08	2.62	2.54	7.43	8.68	4.17	0.38	-1.38	0.03	0.28	down	yes
MSTRG.10331	ATP2A1-AS1	ENST00000561547;ENST00000566956;MSTRG.10331.1;MSTRG.10331.2	NA	NA	NA	NA	NA	1.74	1.59	1.76	5.15	5.67	3.98	0.45	-1.16	0.01	0.21	down	yes
MSTRG.10355	SLC7A5P1	ENST00000566127;MSTRG.10355.2;ENST00000623486;ENST00000568957	NA	NA	NA	NA	NA	5.24	5.44	4.7	1.78	2.01	1.47	2.16	1.11	0	0.17	up	yes
MSTRG.10358	KIF22	ENST00000561482;ENST00000160827;ENST00000569636;MSTRG.10358.4;ENST00000570173;ENST00000400751;ENST00000569382;ENST00000563666;ENST00000563263;ENST00000565736;ENST00000568312	GO:0000776(kinetochore);GO:0000785(chromatin);GO:0003677(DNA binding);GO:0003777(microtubule motor activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0006281(DNA repair);GO:0007018(microtubule-based movement);GO:0007062(sister chromatid cohesion);GO:0007067(mitotic nuclear division);GO:0007080(mitotic metaphase plate congression);GO:0007596(blood coagulation);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II)	NA	NA	NA	kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391]	7.49	6.8	4.66	34.17	39.42	23.64	0.21	-2.23	0.01	0.23	down	yes
MSTRG.10366	SEZ6L2	ENST00000346932;ENST00000350527;ENST00000308713;ENST00000537485;ENST00000617533;ENST00000563118;ENST00000568407;ENST00000562159	GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0008344(adult locomotory behavior);GO:0016021(integral component of membrane);GO:0021680(cerebellar Purkinje cell layer development);GO:0043025(neuronal cell body);GO:0060074(synapse maturation);GO:0090036(regulation of protein kinase C signaling)	NA	NA	NA	seizure related 6 homolog (mouse)-like 2 [Source:HGNC Symbol;Acc:HGNC:30844]	28.73	28.52	28.67	5.93	6.33	17.73	3.82	1.93	0.05	0.33	up	yes
MSTRG.10368	KCTD13	ENST00000308768;ENST00000568000;ENST00000566842;ENST00000568995;ENST00000563955;ENST00000563264;ENST00000566413;ENST00000561540;ENST00000568721	GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0016477(cell migration);GO:0016567(protein ubiquitination);GO:0017049(GTP-Rho binding);GO:0019904(protein domain specific binding);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0035024(negative regulation of Rho protein signal transduction);GO:0042802(identical protein binding);GO:0043149(stress fiber assembly);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0045740(positive regulation of DNA replication);GO:0051260(protein homooligomerization)	NA	NA	NA	potassium channel tetramerization domain containing 13 [Source:HGNC Symbol;Acc:HGNC:22234]	3.54	3.77	2.93	1.26	0.56	1.12	2.15	1.1	0.02	0.27	up	yes
MSTRG.10373	TMEM219	ENST00000414689;ENST00000602948;ENST00000279396;MSTRG.10373.4;ENST00000575829;ENST00000561899;ENST00000566848;ENST00000570255;ENST00000569445;ENST00000569481	GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 219 [Source:HGNC Symbol;Acc:HGNC:25201]	21.44	17.59	18.9	8.34	8.81	13.32	2.19	1.13	0.01	0.23	up	yes
MSTRG.10375	HIRIP3	ENST00000279392;MSTRG.10375.2;ENST00000564026;ENST00000563053;ENST00000563680;ENST00000565996;ENST00000568880	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006333(chromatin assembly or disassembly)	NA	NA	NA	HIRA interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:4917]	4.82	4.49	5.09	17.06	16.43	9.58	0.35	-1.52	0.02	0.26	down	yes
MSTRG.10389	CORO1A	ENST00000219150;ENST00000568763;ENST00000568982;ENST00000570045;ENST00000569469;ENST00000569203;ENST00000569970;ENST00000567034;ENST00000564768;ENST00000562129	GO:0001772(immunological synapse);GO:0001845(phagolysosome assembly);GO:0001891(phagocytic cup);GO:0003779(actin binding);GO:0003785(actin monomer binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0006816(calcium ion transport);GO:0006909(phagocytosis);GO:0006928(movement of cell or subcellular component);GO:0007015(actin filament organization);GO:0008022(protein C-terminus binding);GO:0008064(regulation of actin polymerization or depolymerization);GO:0008092(cytoskeletal protein binding);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016477(cell migration);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030335(positive regulation of cell migration);GO:0030424(axon);GO:0030595(leukocyte chemotaxis);GO:0030670(phagocytic vesicle membrane);GO:0030833(regulation of actin filament polymerization);GO:0030864(cortical actin cytoskeleton);GO:0031252(cell leading edge);GO:0031339(negative regulation of vesicle fusion);GO:0031589(cell-substrate adhesion);GO:0032036(myosin heavy chain binding);GO:0032796(uropod organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0034097(response to cytokine);GO:0038180(nerve growth factor signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043029(T cell homeostasis);GO:0043234(protein complex);GO:0043320(natural killer cell degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0045335(phagocytic vesicle);GO:0048873(homeostasis of number of cells within a tissue);GO:0050870(positive regulation of T cell activation);GO:0050918(positive chemotaxis);GO:0051015(actin filament binding);GO:0051126(negative regulation of actin nucleation);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0061502(early endosome to recycling endosome transport);GO:0070062(extracellular exosome);GO:0071353(cellular response to interleukin-4)	04145(Phagosome);05152(Tuberculosis)	NA	NA	"coronin, actin binding protein, 1A [Source:HGNC Symbol;Acc:HGNC:2252]"	0.16	0.22	0.14	2.03	2.42	1.87	0.35	-1.5	0	0.13	down	yes
MSTRG.10394	SMG1P5	ENST00000529428;ENST00000532983;MSTRG.10394.3;MSTRG.10394.4;MSTRG.10394.6;MSTRG.10394.5;MSTRG.10394.7;ENST00000411546	NA	NA	NA	NA	NA	5.22	4.65	4.48	1.13	2.28	1.8	2.42	1.28	0.01	0.22	up	yes
MSTRG.10405	DCTPP1	ENST00000319285;ENST00000568434;ENST00000568973;ENST00000565758	GO:0000287(magnesium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0009143(nucleoside triphosphate catabolic process);GO:0016462(pyrophosphatase activity);GO:0032556(pyrimidine deoxyribonucleotide binding);GO:0042802(identical protein binding);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0047840(dCTP diphosphatase activity);GO:0051289(protein homotetramerization)	NA	NA	NA	dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777]	12.1	10.05	10.05	25.16	31.16	24.37	0.45	-1.15	0.01	0.2	down	yes
MSTRG.10419	ZNF689	ENST00000287461;ENST00000563304;ENST00000566673;ENST00000565710	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0035914(skeletal muscle cell differentiation);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 689 [Source:HGNC Symbol;Acc:HGNC:25173]	0.29	0.64	1.94	4.64	5.92	4.53	0.28	-1.86	0.04	0.31	down	yes
MSTRG.10456	FUS	ENST00000254108;ENST00000566605;ENST00000487045;ENST00000380244;MSTRG.10456.5;ENST00000487509;ENST00000568685;ENST00000487974;ENST00000570090;ENST00000474990;ENST00000568901;ENST00000564766;ENST00000569760;ENST00000483853	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005844(polysome);GO:0008270(zinc ion binding);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030331(estrogen receptor binding);GO:0030425(dendrite);GO:0031489(myosin V binding);GO:0035255(ionotropic glutamate receptor binding);GO:0042802(identical protein binding);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043204(perikaryon);GO:0044327(dendritic spine head);GO:0044822(poly(A) RNA binding);GO:0046965(retinoid X receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0048471(perinuclear region of cytoplasm);GO:0071277(cellular response to calcium ion);GO:1903506(regulation of nucleic acid-templated transcription)"	NA	NA	NA	FUS RNA binding protein [Source:HGNC Symbol;Acc:HGNC:4010]	6.87	6.08	11.62	57.08	57.73	38.64	0.16	-2.63	0.01	0.22	down	yes
MSTRG.10466	C16orf58	ENST00000570164;MSTRG.10466.2;MSTRG.10466.3;ENST00000327237;ENST00000568491;ENST00000430477;ENST00000567994;ENST00000567673;ENST00000541442;ENST00000565128;ENST00000567578;ENST00000564807;ENST00000566148	GO:0016020(membrane);GO:0016021(integral component of membrane)	NA	NA	NA	chromosome 16 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:25848]	26.94	14.72	29.23	6	9.95	11.88	3.37	1.75	0.01	0.23	up	yes
MSTRG.10490	ORC6	ENST00000563599;ENST00000219097;ENST00000569239;ENST00000563306;ENST00000568364;ENST00000570260;ENST00000566860;ENST00000575571;ENST00000567000	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000808(origin recognition complex);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005664(nuclear origin of replication recognition complex);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0016020(membrane)	04110(Cell cycle)	NA	NA	"origin recognition complex, subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151]"	1.34	2.62	1.77	9.89	6.29	4.37	0.27	-1.88	0	0.16	down	yes
MSTRG.10563	IRX5	ENST00000394636;ENST00000320990;ENST00000558597	"GO:0002027(regulation of heart rate);GO:0003677(DNA binding);GO:0005499(vitamin D binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007601(visual perception);GO:0008406(gonad development);GO:0010468(regulation of gene expression);GO:0042551(neuron maturation);GO:0043565(sequence-specific DNA binding);GO:0048468(cell development);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0050896(response to stimulus);GO:0060040(retinal bipolar neuron differentiation)"	NA	NA	NA	iroquois homeobox 5 [Source:HGNC Symbol;Acc:HGNC:14361]	3	2.72	1.36	0.21	0.73	0.98	2.44	1.29	0.05	0.33	up	yes
MSTRG.10591	MT1X	ENST00000394485;ENST00000562939;ENST00000568370;ENST00000564974	GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0010038(response to metal ion);GO:0036018(cellular response to erythropoietin);GO:0045926(negative regulation of growth);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0071276(cellular response to cadmium ion);GO:0071294(cellular response to zinc ion)	04978(Mineral absorption)	NA	NA	metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405]	16.63	14.06	47.32	1.97	2.62	3.14	8.03	3.01	0.03	0.29	up	yes
MSTRG.10594	HERPUD1	MSTRG.10594.1;ENST00000439977;ENST00000562914;ENST00000568676;ENST00000569569;ENST00000565966;ENST00000300302;ENST00000344114;ENST00000570273;ENST00000379792;ENST00000569429;ENST00000563343;ENST00000566550;ENST00000563781;ENST00000564678;ENST00000563911;ENST00000567944;ENST00000568651;ENST00000568814	"GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0006986(response to unfolded protein);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030970(retrograde protein transport, ER to cytosol);GO:0031396(regulation of protein ubiquitination);GO:0032092(positive regulation of protein binding);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0034704(calcium channel complex);GO:0034976(response to endoplasmic reticulum stress);GO:0036499(PERK-mediated unfolded protein response);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0044267(cellular protein metabolic process);GO:0044325(ion channel binding);GO:1902235(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903069(regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:1990037(Lewy body core);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)"	04141(Protein processing in endoplasmic reticulum)	NA	NA	"homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 [Source:HGNC Symbol;Acc:HGNC:13744]"	42.42	39.37	52.02	3.96	3.71	5.29	9.2	3.2	0	0.13	up	yes
MSTRG.10595	RP11-325K4.3	ENST00000565861	NA	NA	NA	NA	NA	1.31	0.56	0.35	0.05	0.04	0.04	2.36	1.24	0.04	0.31	up	yes
MSTRG.10613	ADGRG1	ENST00000565587;ENST00000567553;ENST00000564912;ENST00000564907;ENST00000566778;ENST00000567835;ENST00000569372;ENST00000563548;ENST00000561833;ENST00000565013;ENST00000561696;ENST00000562414;ENST00000568487;MSTRG.10613.25;ENST00000562631;ENST00000563445;ENST00000565338;MSTRG.10613.30;ENST00000567702;MSTRG.10613.32;ENST00000456916;ENST00000567154;ENST00000388813;MSTRG.10613.37;ENST00000563007;ENST00000562558;ENST00000566271;ENST00000568645;ENST00000563374;ENST00000568234;ENST00000565770;ENST00000564338;ENST00000566164;ENST00000567397;ENST00000568979;ENST00000569992;ENST00000566123;ENST00000562682;ENST00000561782;ENST00000564783;ENST00000564729;ENST00000566508;ENST00000567915;ENST00000569132;ENST00000564103;ENST00000562467;ENST00000568700;ENST00000540164;ENST00000568531;ENST00000568074;ENST00000563414;ENST00000568618;ENST00000569494;ENST00000566169;ENST00000569154;ENST00000569101;ENST00000563862;ENST00000569158;ENST00000566187;ENST00000565505;ENST00000565391	GO:0001525(angiogenesis);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005518(collagen binding);GO:0005622(intracellular);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0007267(cell-cell signaling);GO:0007420(brain development);GO:0008285(negative regulation of cell proliferation);GO:0010573(vascular endothelial growth factor production);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0021796(cerebral cortex regionalization);GO:0021801(cerebral cortex radial glia guided migration);GO:0021819(layer formation in cerebral cortex);GO:0035025(positive regulation of Rho protein signal transduction);GO:0045785(positive regulation of cell adhesion);GO:0050840(extracellular matrix binding);GO:0070062(extracellular exosome);GO:0070528(protein kinase C signaling);GO:0097451(glial limiting end-foot);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2001223(negative regulation of neuron migration)	NA	NA	NA	adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]	26.58	21.51	17.33	2.71	2.33	2.13	7.04	2.82	0	0.15	up	yes
MSTRG.10632	GINS3	ENST00000564814;ENST00000426538;ENST00000328514;ENST00000318129;ENST00000567909;ENST00000567143	GO:0005654(nucleoplasm);GO:0006260(DNA replication)	NA	NA	NA	GINS complex subunit 3 (Psf3 homolog) [Source:HGNC Symbol;Acc:HGNC:25851]	0.15	1.45	1.1	4.66	4.15	3.43	0.23	-2.11	0	0.17	down	yes
MSTRG.10685	CBFB	ENST00000561924;ENST00000290858;ENST00000564034;ENST00000412916;ENST00000565389;ENST00000563939;ENST00000567947;ENST00000566281;ENST00000568858	GO:0000209(protein polyubiquitination);GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0016020(membrane);GO:0030098(lymphocyte differentiation);GO:0030099(myeloid cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048469(cell maturation);GO:0060216(definitive hemopoiesis);GO:1903506(regulation of nucleic acid-templated transcription)	NA	NA	NA	"core-binding factor, beta subunit [Source:HGNC Symbol;Acc:HGNC:1539]"	5.4	19.63	13.74	23.72	22.75	14.39	0.36	-1.49	0.02	0.25	down	yes
MSTRG.10689	NOL3	ENST00000565560;MSTRG.10689.2;ENST00000563439;ENST00000268605;ENST00000568086;ENST00000564992;ENST00000564053;ENST00000565645;ENST00000566871;ENST00000568503;ENST00000563258;ENST00000568146;ENST00000564860	GO:0001666(response to hypoxia);GO:0001974(blood vessel remodeling);GO:0002931(response to ischemia);GO:0003723(RNA binding);GO:0005102(receptor binding);GO:0005123(death receptor binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006376(mRNA splice site selection);GO:0008380(RNA splicing);GO:0010468(regulation of gene expression);GO:0010659(cardiac muscle cell apoptotic process);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0014736(negative regulation of muscle atrophy);GO:0014808(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0014876(response to injury involved in regulation of muscle adaptation);GO:0016528(sarcoplasm);GO:0016529(sarcoplasmic reticulum);GO:0035877(death effector domain binding);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0042802(identical protein binding);GO:0042981(regulation of apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051259(protein oligomerization);GO:0060547(negative regulation of necrotic cell death);GO:0089720(caspase binding);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097193(intrinsic apoptotic signaling pathway);GO:1902109(negative regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)	NA	NA	NA	nucleolar protein 3 (apoptosis repressor with CARD domain) [Source:HGNC Symbol;Acc:HGNC:7869]	7.94	5.97	7.23	2.63	3.22	1.58	2.38	1.25	0.03	0.3	up	yes
MSTRG.10720	CENPT	ENST00000569862;MSTRG.10720.1;ENST00000562787;ENST00000562513;ENST00000436104;ENST00000565157;MSTRG.10720.4;ENST00000626059;ENST00000568495;ENST00000574569;ENST00000563885;ENST00000566758;ENST00000564128;ENST00000562462;ENST00000565713;ENST00000566067;ENST00000562338;ENST00000568564;ENST00000561593;ENST00000565114;ENST00000569094;ENST00000568765;ENST00000565436	"GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0034080(CENP-A containing nucleosome assembly);GO:0046982(protein heterodimerization activity);GO:0051276(chromosome organization);GO:0051301(cell division);GO:0051382(kinetochore assembly)"	NA	NA	NA	centromere protein T [Source:HGNC Symbol;Acc:HGNC:25787]	1.17	0.89	1.43	3.65	4.02	2.41	0.48	-1.07	0.04	0.31	down	yes
MSTRG.10763	CHTF8	ENST00000306585;ENST00000448552;MSTRG.10763.3;ENST00000523421;MSTRG.10763.5;ENST00000518041;MSTRG.10763.7;ENST00000519534;ENST00000398235;ENST00000519520;ENST00000567763;ENST00000522497;ENST00000520529;ENST00000522091	GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006260(DNA replication);GO:0007049(cell cycle);GO:0070062(extracellular exosome)	NA	NA	NA	"CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:24353]"	1.65	1.41	3.78	14.33	17.53	9.78	0.2	-2.31	0.02	0.28	down	yes
MSTRG.10781	WWP2	MSTRG.10781.1;MSTRG.10781.2;ENST00000359154;ENST00000561780;ENST00000569620;ENST00000568845;ENST00000569658;ENST00000569174;ENST00000544162;ENST00000567986;ENST00000570104;ENST00000569297;ENST00000567579;ENST00000566463;MSTRG.10781.18;ENST00000568684;ENST00000568185;ENST00000568818;ENST00000567161;ENST00000567303	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000151(ubiquitin ligase complex);GO:0001085(RNA polymerase II transcription factor binding);GO:0001190(RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006464(cellular protein modification process);GO:0008134(transcription factor binding);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0032410(negative regulation of transporter activity);GO:0034765(regulation of ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046718(viral entry into host cell);GO:0051224(negative regulation of protein transport);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070534(protein K63-linked ubiquitination);GO:1901016(regulation of potassium ion transmembrane transporter activity)"	04120(Ubiquitin mediated proteolysis)	NA	NA	WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16804]	3.31	4.2	4.16	14.88	9.77	11.71	0.33	-1.62	0	0.17	down	yes
MSTRG.10793	AARS	ENST00000261772;ENST00000569825;ENST00000565361;ENST00000564359;ENST00000567490;ENST00000566969	"GO:0000166(nucleotide binding);GO:0001942(hair follicle development);GO:0002161(aminoacyl-tRNA editing activity);GO:0003676(nucleic acid binding);GO:0004813(alanine-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006400(tRNA modification);GO:0006418(tRNA aminoacylation for protein translation);GO:0006419(alanyl-tRNA aminoacylation);GO:0006450(regulation of translational fidelity);GO:0006457(protein folding);GO:0008033(tRNA processing);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016020(membrane);GO:0016876(ligase activity, forming aminoacyl-tRNA and related compounds);GO:0021680(cerebellar Purkinje cell layer development);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0034620(cellular response to unfolded protein);GO:0043039(tRNA aminoacylation);GO:0043200(response to amino acid);GO:0043524(negative regulation of neuron apoptotic process);GO:0043588(skin development);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0070062(extracellular exosome)"	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	alanyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:20]	153.92	162.32	158.37	52.45	42.75	50.23	3.11	1.64	0	0.13	up	yes
MSTRG.10797	ST3GAL2	MSTRG.10797.1;ENST00000393640;MSTRG.10797.2;MSTRG.10797.4;MSTRG.10797.5;ENST00000342907;ENST00000567822;ENST00000566097;ENST00000561708;ENST00000567586	"GO:0000139(Golgi membrane);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0005576(extracellular region);GO:0005975(carbohydrate metabolic process);GO:0006040(amino sugar metabolic process);GO:0006464(cellular protein modification process);GO:0006486(protein glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006493(protein O-linked glycosylation);GO:0008373(sialyltransferase activity);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030173(integral component of Golgi membrane);GO:0030203(glycosaminoglycan metabolic process);GO:0032580(Golgi cisterna membrane);GO:0042339(keratan sulfate metabolic process);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0097503(sialylation)"	00512(Mucin type O-Glycan biosynthesis);00533(Glycosaminoglycan biosynthesis - keratan sulfate);00603(Glycosphingolipid biosynthesis - globo series);00604(Glycosphingolipid biosynthesis - ganglio series);01100(Metabolic pathways)	NA	NA	"ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10863]"	1.09	1.37	2.25	4.3	4.79	5.42	0.43	-1.22	0.03	0.28	down	yes
MSTRG.10801	SF3B3	ENST00000302516;ENST00000566095;MSTRG.10801.2;MSTRG.10801.3;MSTRG.10801.5;ENST00000577085;ENST00000564899;ENST00000572365;ENST00000567635;ENST00000567250;ENST00000568291;ENST00000568539;ENST00000563739;ENST00000562722;ENST00000565990	"GO:0000375(RNA splicing, via transesterification reactions);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005689(U12-type spliceosomal complex);GO:0006397(mRNA processing);GO:0006461(protein complex assembly);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030532(small nuclear ribonucleoprotein complex);GO:0042177(negative regulation of protein catabolic process);GO:0071013(catalytic step 2 spliceosome)"	NA	NA	NA	"splicing factor 3b, subunit 3, 130kDa [Source:HGNC Symbol;Acc:HGNC:10770]"	11.85	13.6	15.87	27.48	27.56	28.52	0.49	-1.04	0.01	0.2	down	yes
MSTRG.1084	INADL	MSTRG.1084.2;MSTRG.1084.1;ENST00000316485;ENST00000484562;ENST00000371158;ENST00000484937;ENST00000488913;ENST00000494842;ENST00000490547;ENST00000307297;ENST00000465798;ENST00000472512	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005923(bicellular tight junction);GO:0016324(apical plasma membrane);GO:0034329(cell junction assembly);GO:0035556(intracellular signal transduction);GO:0045177(apical part of cell);GO:0045216(cell-cell junction organization);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0070830(bicellular tight junction assembly)	04530(Tight junction)	NA	NA	InaD-like (Drosophila) [Source:HGNC Symbol;Acc:HGNC:28881]	2.9	3.08	2.65	0.79	0.7	0.64	2.21	1.14	0	0.11	up	yes
MSTRG.10973	CDH13	ENST00000567109;ENST00000268613;ENST00000569144;ENST00000562601;MSTRG.10973.4;ENST00000568770;ENST00000565636;ENST00000431540;ENST00000428848;ENST00000539548;ENST00000566333;ENST00000569455;ENST00000567445;ENST00000566620;ENST00000622885;ENST00000569454;ENST00000562307;ENST00000615627	GO:0000278(mitotic cell cycle);GO:0001558(regulation of cell growth);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002040(sprouting angiogenesis);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0007266(Rho protein signal transduction);GO:0008285(negative regulation of cell proliferation);GO:0009897(external side of plasma membrane);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0016601(Rac protein signal transduction);GO:0030032(lamellipodium assembly);GO:0030100(regulation of endocytosis);GO:0030169(low-density lipoprotein particle binding);GO:0030335(positive regulation of cell migration);GO:0031225(anchored component of membrane);GO:0034329(cell junction assembly);GO:0034332(adherens junction organization);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0043542(endothelial cell migration);GO:0043616(keratinocyte proliferation);GO:0045216(cell-cell junction organization);GO:0045296(cadherin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048471(perinuclear region of cytoplasm);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050927(positive regulation of positive chemotaxis);GO:0051668(localization within membrane);GO:0055096(low-density lipoprotein particle mediated signaling);GO:0055100(adiponectin binding);GO:0070062(extracellular exosome);GO:0071813(lipoprotein particle binding)	NA	NA	NA	cadherin 13 [Source:HGNC Symbol;Acc:HGNC:1753]	30.81	34.68	29.58	15.73	13.83	9.52	2.04	1.03	0.02	0.26	up	yes
MSTRG.11020	RP11-118F19.1	ENST00000602862	NA	NA	NA	NA	NA	2.16	1.47	2.65	8.95	7.85	10.45	0.34	-1.57	0.01	0.21	down	yes
MSTRG.11023	GINS2	ENST00000253462;ENST00000595355;ENST00000596233	GO:0000278(mitotic cell cycle);GO:0000727(double-strand break repair via break-induced replication);GO:0000811(GINS complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0031298(replication fork protection complex);GO:0032508(DNA duplex unwinding);GO:0043138(3'-5' DNA helicase activity);GO:1902975(mitotic DNA replication initiation)	NA	NA	NA	GINS complex subunit 2 (Psf2 homolog) [Source:HGNC Symbol;Acc:HGNC:24575]	0.94	0.97	1.08	10.27	9.65	12.31	0.18	-2.51	0	0.11	down	yes
MSTRG.11032	RP11-514D23.3	MSTRG.11032.1;ENST00000602425	NA	NA	NA	NA	NA	3.96	4.62	6.2	0	0	0	5.55	2.47	0	0.14	up	yes
MSTRG.11083	.	MSTRG.11083.1	NA	NA	NA	NA	NA	0	0.4	0.28	1.23	1.4	1.33	0.47	-1.08	0.01	0.2	down	yes
MSTRG.11099	CDT1	ENST00000301019;ENST00000562747;ENST00000569140	GO:0000076(DNA replication checkpoint);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0030174(regulation of DNA-dependent DNA replication initiation);GO:0033262(regulation of nuclear cell cycle DNA replication)	NA	NA	NA	chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576]	4.04	3.68	2.98	10.89	12.75	6.9	0.39	-1.34	0.04	0.3	down	yes
MSTRG.11106	RP11-46C24.7	ENST00000570267	NA	NA	NA	NA	NA	0.14	0.09	0.36	1.38	1.47	1.52	0.49	-1.02	0.01	0.19	down	yes
MSTRG.11120	RPL13	ENST00000311528;ENST00000491523;ENST00000563749;ENST00000484610;ENST00000563270;ENST00000567815;ENST00000487034;ENST00000562879;ENST00000565571;ENST00000452368;ENST00000467736;ENST00000393099;ENST00000399461;ENST00000570149;ENST00000472354	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0022626(cytosolic ribosome);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:10303]	162.15	141.56	185.02	60.13	74.96	130.63	2.41	1.27	0.05	0.33	up	yes
MSTRG.11130	FANCA	MSTRG.11130.1;ENST00000389301;MSTRG.11130.3;ENST00000568369;ENST00000561722;ENST00000564475;ENST00000564870;ENST00000568626;ENST00000564969;ENST00000305699;ENST00000567988;ENST00000568983;ENST00000563510;ENST00000563318;ENST00000567205;ENST00000561667;ENST00000567284;ENST00000567510;ENST00000563767;ENST00000566133;ENST00000566409;ENST00000566889;ENST00000389302;ENST00000563673;ENST00000534992;ENST00000563513;ENST00000567883;ENST00000567943	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006461(protein complex assembly);GO:0007140(male meiosis);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0042127(regulation of cell proliferation);GO:0043240(Fanconi anaemia nuclear complex)	NA	NA	NA	"Fanconi anemia, complementation group A [Source:HGNC Symbol;Acc:HGNC:3582]"	0.63	0.73	0.69	4.91	4.5	3.24	0.29	-1.77	0	0.15	down	yes
MSTRG.11140	GAS8	ENST00000563980;ENST00000536122;ENST00000565957;ENST00000563936;ENST00000568705;ENST00000568664;ENST00000561675;MSTRG.11140.8;MSTRG.11140.9;ENST00000564392;ENST00000268699;ENST00000620723;ENST00000565062;ENST00000540721;ENST00000564853;ENST00000537797;ENST00000566266;ENST00000569558;ENST00000564802;ENST00000565000;ENST00000569399;ENST00000564789;ENST00000568284	GO:0003674(molecular_function);GO:0005794(Golgi apparatus);GO:0005874(microtubule);GO:0008285(negative regulation of cell proliferation);GO:0017137(Rab GTPase binding);GO:0030317(sperm motility);GO:0031514(motile cilium);GO:0034613(cellular protein localization);GO:0048870(cell motility)	NA	NA	NA	growth arrest-specific 8 [Source:HGNC Symbol;Acc:HGNC:4166]	2.94	2.3	2.66	6.8	6.76	8.39	0.49	-1.04	0	0.14	down	yes
MSTRG.11152	FAM101B	ENST00000329099	GO:0001837(epithelial to mesenchymal transition);GO:0005737(cytoplasm);GO:0015629(actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0031005(filamin binding);GO:0032432(actin filament bundle);GO:0048705(skeletal system morphogenesis);GO:0061182(negative regulation of chondrocyte development);GO:0061572(actin filament bundle organization);GO:1900158(negative regulation of bone mineralization involved in bone maturation)	NA	NA	NA	"family with sequence similarity 101, member B [Source:HGNC Symbol;Acc:HGNC:28705]"	1.63	2.13	1.72	4.88	4.95	5.18	0.45	-1.16	0	0.14	down	yes
MSTRG.11166	TIMM22	MSTRG.11166.1;ENST00000327158	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006626(protein targeting to mitochondrion);GO:0015266(protein channel activity);GO:0016021(integral component of membrane);GO:0044267(cellular protein metabolic process);GO:0045039(protein import into mitochondrial inner membrane)	NA	NA	NA	translocase of inner mitochondrial membrane 22 homolog (yeast) [Source:HGNC Symbol;Acc:HGNC:17317]	3.41	3.32	1.74	6.82	8.51	7.59	0.46	-1.12	0.04	0.33	down	yes
MSTRG.11187	TLCD2	ENST00000330676	GO:0016021(integral component of membrane)	NA	NA	NA	TLC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33522]	3.67	4.38	4.01	0.5	0.54	0.61	3.14	1.65	0	0.1	up	yes
MSTRG.11194	RPA1	ENST00000571058;ENST00000570451;ENST00000254719;ENST00000571725;ENST00000573924;ENST00000574049;ENST00000573994	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000718(nucleotide-excision repair, DNA damage removal);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0000724(double-strand break repair via homologous recombination);GO:0000730(DNA recombinase assembly);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0000800(lateral element);GO:0001673(male germ cell nucleus);GO:0001701(in utero embryonic development);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003684(damaged DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005662(DNA replication factor A complex);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006302(double-strand break repair);GO:0006310(DNA recombination);GO:0007126(meiotic nuclear division);GO:0008284(positive regulation of cell proliferation);GO:0016605(PML body);GO:0016925(protein sumoylation);GO:0019985(translesion synthesis);GO:0030097(hemopoiesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0034605(cellular response to heat);GO:0042276(error-prone translesion synthesis);GO:0042769(DNA damage response, detection of DNA damage);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding);GO:0048873(homeostasis of number of cells within a tissue);GO:0051276(chromosome organization);GO:0070987(error-free translesion synthesis);GO:1900034(regulation of cellular response to heat)"	03030(DNA replication);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination)	NA	NA	"replication protein A1, 70kDa [Source:HGNC Symbol;Acc:HGNC:10289]"	10.5	11.83	10.45	27.81	27.91	14.34	0.42	-1.24	0.04	0.33	down	yes
MSTRG.11266	MED11	ENST00000575284;ENST00000573708;ENST00000293777	"GO:0000151(ubiquitin ligase complex);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0005515(protein binding);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0061630(ubiquitin protein ligase activity)"	NA	NA	NA	mediator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:32687]	2.19	3.07	2.56	6.81	7.6	5.55	0.42	-1.26	0	0.17	down	yes
MSTRG.11283	CAMTA2	MSTRG.11283.1;ENST00000575142;MSTRG.11283.9;MSTRG.11283.6;MSTRG.11283.8;MSTRG.11283.10;MSTRG.11283.4;MSTRG.11283.2;MSTRG.11283.3;MSTRG.11283.5;MSTRG.11283.7;ENST00000206020;ENST00000573366;ENST00000575784;ENST00000572148;ENST00000573805;MSTRG.11283.17;ENST00000571023;MSTRG.11283.20;MSTRG.11283.19;ENST00000570341;ENST00000574951;ENST00000414043;ENST00000361571;ENST00000572543;ENST00000348066;ENST00000572192;ENST00000574442;ENST00000576872;ENST00000617935;ENST00000614295;ENST00000572326;ENST00000575192;ENST00000575365;ENST00000574606;ENST00000571831;ENST00000575580	"GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0042826(histone deacetylase binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	calmodulin binding transcription activator 2 [Source:HGNC Symbol;Acc:HGNC:18807]	16.27	14.69	12.41	5.34	5.64	5.89	2.47	1.31	0	0.17	up	yes
MSTRG.11305	DHX33	MSTRG.11305.1;ENST00000575890;ENST00000225698;ENST00000574444;ENST00000570805;ENST00000573204;ENST00000573421;ENST00000573406;ENST00000576122;ENST00000225296;ENST00000575153;ENST00000433302;ENST00000572490;ENST00000574023	GO:0000182(rDNA binding);GO:0003676(nucleic acid binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0008026(ATP-dependent helicase activity);GO:0033613(activating transcription factor binding);GO:0044822(poly(A) RNA binding);GO:0045943(positive regulation of transcription from RNA polymerase I promoter)	NA	NA	NA	DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Source:HGNC Symbol;Acc:HGNC:16718]	10.78	14.13	11.87	25.47	24.7	20.04	0.47	-1.08	0	0.14	down	yes
MSTRG.11309	FAM64A	ENST00000572447;ENST00000250056;ENST00000573557;ENST00000571373;ENST00000570337;ENST00000572595;ENST00000576056;ENST00000573385;ENST00000571572	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0007067(mitotic nuclear division);GO:0051301(cell division)	NA	NA	NA	"family with sequence similarity 64, member A [Source:HGNC Symbol;Acc:HGNC:25483]"	2.31	1.38	0.81	21.27	26.72	17.16	0.12	-3.07	0.01	0.19	down	yes
MSTRG.11315	MED31	ENST00000225728;ENST00000575197;ENST00000574128;ENST00000575519	"GO:0000151(ubiquitin ligase complex);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0010467(gene expression);GO:0016567(protein ubiquitination);GO:0016592(mediator complex);GO:0048147(negative regulation of fibroblast proliferation);GO:0060173(limb development);GO:0061630(ubiquitin protein ligase activity)"	NA	NA	NA	mediator complex subunit 31 [Source:HGNC Symbol;Acc:HGNC:24260]	2.49	4.13	3.46	7.25	8.01	6.05	0.45	-1.14	0.01	0.19	down	yes
MSTRG.11327	DLG4	ENST00000489885;ENST00000399506;ENST00000302955;ENST00000399510;MSTRG.11327.5;MSTRG.11327.6;MSTRG.11327.7;MSTRG.11327.8;ENST00000491753;ENST00000485100;ENST00000451807;ENST00000447163;ENST00000486626;ENST00000493294	GO:0002091(negative regulation of receptor internalization);GO:0004385(guanylate kinase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006461(protein complex assembly);GO:0007165(signal transduction);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007264(small GTPase mediated signal transduction);GO:0007268(synaptic transmission);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007612(learning);GO:0008021(synaptic vesicle);GO:0008022(protein C-terminus binding);GO:0008076(voltage-gated potassium channel complex);GO:0008328(ionotropic glutamate receptor complex);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0016188(synaptic vesicle maturation);GO:0019900(kinase binding);GO:0019903(protein phosphatase binding);GO:0030054(cell junction);GO:0030165(PDZ domain binding);GO:0030425(dendrite);GO:0030666(endocytic vesicle membrane);GO:0030863(cortical cytoskeleton);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0031697(beta-1 adrenergic receptor binding);GO:0031748(D1 dopamine receptor binding);GO:0031812(P2Y1 nucleotide receptor binding);GO:0032281(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex);GO:0032403(protein complex binding);GO:0032839(dendrite cytoplasm);GO:0033130(acetylcholine receptor binding);GO:0035176(social behavior);GO:0035255(ionotropic glutamate receptor binding);GO:0035418(protein localization to synapse);GO:0035641(locomotory exploration behavior);GO:0043197(dendritic spine);GO:0044224(juxtaparanode region of axon);GO:0044300(cerebellar mossy fiber);GO:0044306(neuron projection terminus);GO:0044309(neuron spine);GO:0045184(establishment of protein localization);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0046939(nucleotide phosphorylation);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050806(positive regulation of synaptic transmission);GO:0050885(neuromuscular process controlling balance);GO:0060076(excitatory synapse);GO:0060997(dendritic spine morphogenesis);GO:0071625(vocalization behavior);GO:0097060(synaptic membrane);GO:0097109(neuroligin family protein binding);GO:0097110(scaffold protein binding);GO:0097113(alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering);GO:0097120(receptor localization to synapse);GO:0097481(neuronal postsynaptic density);GO:2000310(regulation of N-methyl-D-aspartate selective glutamate receptor activity);GO:2000463(positive regulation of excitatory postsynaptic membrane potential);GO:2000821(regulation of grooming behavior)	04724(Glutamatergic synapse);05016(Huntington's disease)	NA	NA	"discs, large homolog 4 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:2903]"	10.76	9.38	7.78	3.24	3.57	7.11	2.33	1.22	0.04	0.33	up	yes
MSTRG.11336	EIF5A	MSTRG.11336.1;ENST00000336452;ENST00000355068;ENST00000336458;ENST00000576930;ENST00000572815;ENST00000573542;ENST00000575001;ENST00000419711;ENST00000573714;ENST00000416016	GO:0003723(RNA binding);GO:0003746(translation elongation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005642(annulate lamellae);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006406(mRNA export from nucleus);GO:0006452(translational frameshifting);GO:0006611(protein export from nucleus);GO:0006913(nucleocytoplasmic transport);GO:0006915(apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0016020(membrane);GO:0017070(U6 snRNA binding);GO:0043022(ribosome binding);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0045901(positive regulation of translational elongation);GO:0045905(positive regulation of translational termination);GO:0047485(protein N-terminus binding);GO:0070062(extracellular exosome)	NA	NA	NA	eukaryotic translation initiation factor 5A [Source:HGNC Symbol;Acc:HGNC:3300]	84.65	101.61	75.01	179.1	239.55	191.8	0.42	-1.25	0.02	0.25	down	yes
MSTRG.11358	SAT2	ENST00000576846;ENST00000269298;MSTRG.11358.1;MSTRG.11358.2;ENST00000570914;ENST00000380466;ENST00000576579;ENST00000571074;ENST00000575826;ENST00000571195;ENST00000573566;ENST00000570850;ENST00000576686;ENST00000572224;ENST00000575114;ENST00000573930	GO:0004145(diamine N-acetyltransferase activity);GO:0005737(cytoplasm);GO:0008080(N-acetyltransferase activity);GO:0008152(metabolic process);GO:0009447(putrescine catabolic process);GO:0032918(spermidine acetylation);GO:0032919(spermine acetylation);GO:0032920(putrescine acetylation);GO:0046204(nor-spermidine metabolic process);GO:0070062(extracellular exosome)	00330(Arginine and proline metabolism);01100(Metabolic pathways)	NA	NA	spermidine/spermine N1-acetyltransferase family member 2 [Source:HGNC Symbol;Acc:HGNC:23160]	36.19	31.72	20.91	9.5	11.42	10.58	2.86	1.51	0.02	0.26	up	yes
MSTRG.11362	WRAP53	ENST00000431639;ENST00000316024;ENST00000498311;ENST00000396463;ENST00000467699;ENST00000471973;ENST00000498114	GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005697(telomerase holoenzyme complex);GO:0005737(cytoplasm);GO:0015030(Cajal body);GO:0032203(telomere formation via telomerase);GO:0051973(positive regulation of telomerase activity)	NA	NA	NA	"WD repeat containing, antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522]"	1.3	1.03	0.84	4.28	4.83	3.36	0.4	-1.31	0.01	0.22	down	yes
MSTRG.11364	KDM6B	MSTRG.11364.1;MSTRG.11364.2;MSTRG.11364.4;ENST00000571047;ENST00000254846;ENST00000448097;ENST00000572030;MSTRG.11364.9;MSTRG.11364.10	NA	NA	NA	NA	NA	10.05	8.72	9.8	1.57	1.1	3.48	4.27	2.09	0.02	0.25	up	yes
MSTRG.11366	NAA38	MSTRG.11366.2;MSTRG.11366.1;ENST00000575071;ENST00000333775;ENST00000575771;ENST00000575208;ENST00000576861;ENST00000576384;ENST00000570555;MSTRG.11366.10	NA	NA	NA	NA	NA	4.29	4.75	3.52	9.29	8.57	9.79	0.5	-1	0.01	0.21	down	yes
MSTRG.11371	HES7	ENST00000541682;ENST00000577735	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0001756(somitogenesis);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007219(Notch signaling pathway);GO:0007498(mesoderm development);GO:0008134(transcription factor binding);GO:0014807(regulation of somitogenesis);GO:0036342(post-anal tail morphogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046983(protein dimerization activity);GO:0048511(rhythmic process)"	NA	NA	NA	hes family bHLH transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:15977]	2.46	1.35	2	0.02	0.21	0.51	2.96	1.56	0	0.11	up	yes
MSTRG.11374	CNTROB	ENST00000576538;ENST00000380262;ENST00000563694;MSTRG.11374.4;MSTRG.11374.5;MSTRG.11374.6;MSTRG.11374.8;ENST00000570784;ENST00000575408;ENST00000565740;ENST00000571540;ENST00000571632;ENST00000576587;ENST00000574430;ENST00000576723;ENST00000573862;ENST00000576536	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0007099(centriole replication);GO:0019904(protein domain specific binding);GO:0051299(centrosome separation);GO:1902410(mitotic cytokinetic process)	NA	NA	NA	"centrobin, centrosomal BRCA2 interacting protein [Source:HGNC Symbol;Acc:HGNC:29616]"	2.5	2.59	2.69	7.2	7.6	5.63	0.44	-1.19	0	0.18	down	yes
MSTRG.11375	VAMP2	ENST00000317276;MSTRG.11375.1;MSTRG.11375.2;ENST00000581082;ENST00000582719;ENST00000583677;ENST00000579098;ENST00000578089;ENST00000578950;MSTRG.11375.10;ENST00000354903;ENST00000581395;ENST00000585095;ENST00000577424;ENST00000579203;ENST00000578223;ENST00000579065;ENST00000581703;ENST00000577253;ENST00000584202;ENST00000316509;MSTRG.11375.25;ENST00000404970;ENST00000488857;ENST00000481878	GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005543(phospholipid binding);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006112(energy reserve metabolic process);GO:0006461(protein complex assembly);GO:0006887(exocytosis);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006906(vesicle fusion);GO:0007268(synaptic transmission);GO:0007269(neurotransmitter secretion);GO:0008021(synaptic vesicle);GO:0008022(protein C-terminus binding);GO:0008076(voltage-gated potassium channel complex);GO:0009749(response to glucose);GO:0014047(glutamate secretion);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016079(synaptic vesicle exocytosis);GO:0016192(vesicle-mediated transport);GO:0017022(myosin binding);GO:0017075(syntaxin-1 binding);GO:0017156(calcium ion-dependent exocytosis);GO:0017157(regulation of exocytosis);GO:0019905(syntaxin binding);GO:0030054(cell junction);GO:0030136(clathrin-coated vesicle);GO:0030141(secretory granule);GO:0030667(secretory granule membrane);GO:0030672(synaptic vesicle membrane);GO:0031201(SNARE complex);GO:0031410(cytoplasmic vesicle);GO:0032403(protein complex binding);GO:0032869(cellular response to insulin stimulus);GO:0042589(zymogen granule membrane);GO:0042802(identical protein binding);GO:0043001(Golgi to plasma membrane protein transport);GO:0043005(neuron projection);GO:0043195(terminal bouton);GO:0043229(intracellular organelle);GO:0043231(intracellular membrane-bounded organelle);GO:0043308(eosinophil degranulation);GO:0043621(protein self-association);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0044306(neuron projection terminus);GO:0045202(synapse);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0050796(regulation of insulin secretion);GO:0060203(clathrin-sculpted glutamate transport vesicle membrane);GO:0060291(long-term synaptic potentiation);GO:0060627(regulation of vesicle-mediated transport);GO:0061024(membrane organization);GO:0061025(membrane fusion);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0070032(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex);GO:0070033(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex);GO:0070044(synaptobrevin 2-SNAP-25-syntaxin-1a complex);GO:0070062(extracellular exosome);GO:0070083(clathrin-sculpted monoamine transport vesicle membrane);GO:0090316(positive regulation of intracellular protein transport);GO:1902259(regulation of delayed rectifier potassium channel activity)	04130(SNARE interactions in vesicular transport);04962(Vasopressin-regulated water reabsorption);04970(Salivary secretion)	NA	NA	vesicle-associated membrane protein 2 (synaptobrevin 2) [Source:HGNC Symbol;Acc:HGNC:12643]	11.35	9.75	8.18	1.67	1.74	3.7	3.97	1.99	0.01	0.22	up	yes
MSTRG.11381	AURKB	MSTRG.11381.1;ENST00000316199;ENST00000534871;ENST00000585124;ENST00000584972;ENST00000578549;ENST00000580998;ENST00000578753;ENST00000577833;ENST00000581511;ENST00000580390;ENST00000584561;ENST00000582368;ENST00000583915;ENST00000583124	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000779(condensed chromosome, centromeric region);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0002903(negative regulation of B cell apoptotic process);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0006468(protein phosphorylation);GO:0007052(mitotic spindle organization);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0008608(attachment of spindle microtubules to kinetochore);GO:0009838(abscission);GO:0009966(regulation of signal transduction);GO:0010369(chromocenter);GO:0016570(histone modification);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030496(midbody);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031577(spindle checkpoint);GO:0031616(spindle pole centrosome);GO:0032091(negative regulation of protein binding);GO:0032133(chromosome passenger complex);GO:0032466(negative regulation of cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0034501(protein localization to kinetochore);GO:0034644(cellular response to UV);GO:0035174(histone serine kinase activity);GO:0036089(cleavage furrow formation);GO:0043146(spindle stabilization);GO:0043988(histone H3-S28 phosphorylation);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0051233(spindle midzone);GO:0051256(mitotic spindle midzone assembly);GO:0051983(regulation of chromosome segregation)"	NA	NA	NA	aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390]	2.84	2.33	1.11	24.4	27.14	15.07	0.13	-2.96	0.01	0.23	down	yes
MSTRG.11383	PFAS	ENST00000585183;MSTRG.11383.2;ENST00000584044;ENST00000580356;ENST00000314666;ENST00000581242;ENST00000585319;ENST00000581288;ENST00000578979;ENST00000546020;ENST00000580251	GO:0003824(catalytic activity);GO:0004642(phosphoribosylformylglycinamidine synthase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006144(purine nucleobase metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0006189('de novo' IMP biosynthetic process);GO:0006541(glutamine metabolic process);GO:0009156(ribonucleoside monophosphate biosynthetic process);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0044281(small molecule metabolic process);GO:0046872(metal ion binding);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0070062(extracellular exosome)	00230(Purine metabolism);01100(Metabolic pathways)	NA	NA	phosphoribosylformylglycinamidine synthase [Source:HGNC Symbol;Acc:HGNC:8863]	2.07	2.06	3.29	6.16	6.99	8.56	0.45	-1.16	0.03	0.28	down	yes
MSTRG.11390	RPL26	ENST00000396267;ENST00000582471;ENST00000331336;ENST00000293842;MSTRG.11390.4;ENST00000584164;ENST00000578069;ENST00000584441;ENST00000582485;ENST00000582556;ENST00000584906;ENST00000583011;ENST00000585176;ENST00000584343;ENST00000578812;ENST00000583515;ENST00000578115	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006364(rRNA processing);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0015934(large ribosomal subunit);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0042273(ribosomal large subunit biogenesis);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome)"	03010(Ribosome)	NA	NA	ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327]	201.82	204.71	177.33	88.04	97.48	117.61	2.07	1.05	0.01	0.22	up	yes
MSTRG.11391	NDEL1	ENST00000580237;ENST00000582665;ENST00000579880;ENST00000334527;ENST00000585098;ENST00000380025;ENST00000402554;ENST00000584866;ENST00000582490;ENST00000580738;ENST00000583066;ENST00000580012;ENST00000581189;ENST00000582277;ENST00000581679;ENST00000583683;ENST00000578172	GO:0000132(establishment of mitotic spindle orientation);GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0001764(neuron migration);GO:0001833(inner cell mass cell proliferation);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005875(microtubule associated complex);GO:0006508(proteolysis);GO:0007020(microtubule nucleation);GO:0007059(chromosome segregation);GO:0007100(mitotic centrosome separation);GO:0007264(small GTPase mediated signal transduction);GO:0008017(microtubule binding);GO:0008090(retrograde axon cargo transport);GO:0010975(regulation of neuron projection development);GO:0016477(cell migration);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021955(central nervous system neuron axonogenesis);GO:0030424(axon);GO:0031175(neuron projection development);GO:0031252(cell leading edge);GO:0032403(protein complex binding);GO:0033157(regulation of intracellular protein transport);GO:0043014(alpha-tubulin binding);GO:0043203(axon hillock);GO:0043547(positive regulation of GTPase activity);GO:0044297(cell body);GO:0045773(positive regulation of axon extension);GO:0047496(vesicle transport along microtubule);GO:0048487(beta-tubulin binding);GO:0048680(positive regulation of axon regeneration);GO:0051081(nuclear envelope disassembly);GO:0051303(establishment of chromosome localization);GO:0051642(centrosome localization);GO:0060052(neurofilament cytoskeleton organization);GO:0060053(neurofilament cytoskeleton);GO:0070012(oligopeptidase activity);GO:0090630(activation of GTPase activity);GO:1990138(neuron projection extension)	NA	NA	NA	nudE neurodevelopment protein 1-like 1 [Source:HGNC Symbol;Acc:HGNC:17620]	8.51	8.38	7.59	2.74	2.98	1.99	2.5	1.32	0.01	0.19	up	yes
MSTRG.11392	MYH10	MSTRG.11392.1;ENST00000360416;ENST00000379980;ENST00000269243;ENST00000476737;ENST00000488329;ENST00000465458;ENST00000469865;MSTRG.11392.9;ENST00000584124;ENST00000472728;ENST00000411957	"GO:0000146(microfilament motor activity);GO:0000281(mitotic cytokinesis);GO:0001701(in utero embryonic development);GO:0001725(stress fiber);GO:0001764(neuron migration);GO:0001778(plasma membrane repair);GO:0003774(motor activity);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005819(spindle);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005903(brush border);GO:0005938(cell cortex);GO:0006887(exocytosis);GO:0006930(substrate-dependent cell migration, cell extension);GO:0007097(nuclear migration);GO:0007155(cell adhesion);GO:0007264(small GTPase mediated signal transduction);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007512(adult heart development);GO:0008152(metabolic process);GO:0008283(cell proliferation);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0016459(myosin complex);GO:0016460(myosin II complex);GO:0021592(fourth ventricle development);GO:0021670(lateral ventricle development);GO:0021678(third ventricle development);GO:0021680(cerebellar Purkinje cell layer development);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030048(actin filament-based movement);GO:0030239(myofibril assembly);GO:0030424(axon);GO:0030426(growth cone);GO:0030496(midbody);GO:0030898(actin-dependent ATPase activity);GO:0031032(actomyosin structure organization);GO:0031175(neuron projection development);GO:0031594(neuromuscular junction);GO:0032154(cleavage furrow);GO:0042641(actomyosin);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043531(ADP binding);GO:0048013(ephrin receptor signaling pathway);GO:0050885(neuromuscular process controlling balance);GO:0051015(actin filament binding);GO:0055003(cardiac myofibril assembly);GO:0055015(ventricular cardiac muscle cell development);GO:0060041(retina development in camera-type eye);GO:0070062(extracellular exosome);GO:0097513(myosin II filament)"	04530(Tight junction);04810(Regulation of actin cytoskeleton);05416(Viral myocarditis)	NA	NA	"myosin, heavy chain 10, non-muscle [Source:HGNC Symbol;Acc:HGNC:7568]"	4.06	4.26	3.21	28.4	20.12	21.34	0.18	-2.45	0	0.15	down	yes
MSTRG.11398	STX8	MSTRG.11398.1;MSTRG.11398.2;MSTRG.11398.4;ENST00000306357;MSTRG.11398.3;ENST00000575858;ENST00000570583;ENST00000570987;ENST00000574431;ENST00000575294;ENST00000574775;ENST00000573016;ENST00000573881;ENST00000574382;ENST00000573077	GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005783(endoplasmic reticulum);GO:0005802(trans-Golgi network);GO:0005887(integral component of plasma membrane);GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0006906(vesicle fusion);GO:0008333(endosome to lysosome transport);GO:0016192(vesicle-mediated transport);GO:0019869(chloride channel inhibitor activity);GO:0019905(syntaxin binding);GO:0031201(SNARE complex);GO:0031625(ubiquitin protein ligase binding);GO:0031902(late endosome membrane);GO:0031982(vesicle);GO:0045022(early endosome to late endosome transport);GO:0048471(perinuclear region of cytoplasm);GO:0055037(recycling endosome);GO:1903076(regulation of protein localization to plasma membrane)	NA	NA	NA	syntaxin 8 [Source:HGNC Symbol;Acc:HGNC:11443]	13.07	12.7	11.52	5.07	5.5	6.71	2.17	1.11	0	0.17	up	yes
MSTRG.11421	ADPRM	ENST00000379774;ENST00000468843;ENST00000527582;ENST00000609540	GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0047631(ADP-ribose diphosphatase activity);GO:0047734(CDP-glycerol diphosphatase activity)	NA	NA	NA	"ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent [Source:HGNC Symbol;Acc:HGNC:30925]"	9.77	8.47	10.48	1.99	2.72	3.38	3.32	1.73	0	0.16	up	yes
MSTRG.11446	ELAC2	ENST00000480891;ENST00000484122;ENST00000338034;ENST00000395962;ENST00000465825;ENST00000487229;ENST00000426905;ENST00000584650;ENST00000491478;ENST00000492559;ENST00000446899;ENST00000578991;ENST00000476042;ENST00000578104;ENST00000609345;ENST00000609101;ENST00000580504;ENST00000581499;ENST00000609757;ENST00000578071	"GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0008033(tRNA processing);GO:0034414(tRNA 3'-trailer cleavage, endonucleolytic);GO:0042781(3'-tRNA processing endoribonuclease activity);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0072684(mitochondrial tRNA 3'-trailer cleavage, endonucleolytic)"	NA	NA	NA	elaC ribonuclease Z 2 [Source:HGNC Symbol;Acc:HGNC:14198]	5.6	6.75	6.71	12.88	15.31	10.54	0.49	-1.04	0.01	0.24	down	yes
MSTRG.11465	TRIM16	MSTRG.11465.4;ENST00000354433;ENST00000395906;ENST00000475944;ENST00000261644;MSTRG.11465.12;MSTRG.11465.13;MSTRG.11465.14;ENST00000577886;ENST00000416464;ENST00000578237;ENST00000577446;MSTRG.11465.20;ENST00000579219;ENST00000577326;ENST00000580110;MSTRG.11465.23;ENST00000473368;ENST00000577372;ENST00000578744;ENST00000473540;ENST00000581224;ENST00000581200;ENST00000460728;ENST00000579272;ENST00000584142;ENST00000473659;ENST00000494759;ENST00000579535;ENST00000582182;ENST00000582708;ENST00000580388;ENST00000579843;ENST00000579630	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0019966(interleukin-1 binding);GO:0032089(NACHT domain binding);GO:0032526(response to retinoic acid);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046683(response to organophosphorus);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0060416(response to growth hormone)"	NA	NA	NA	tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241]	10.52	7.12	6.3	2.4	2.02	2.84	3.07	1.62	0.01	0.2	up	yes
MSTRG.11479	ZSWIM7	MSTRG.11479.1	NA	NA	NA	NA	NA	0.32	1.5	1.96	2.82	2.16	1.24	0.49	-1.02	0.05	0.34	down	yes
MSTRG.11490	LRRC75A-AS1	ENST00000584177;MSTRG.11490.3;MSTRG.11490.2;MSTRG.11490.4;MSTRG.11490.5;ENST00000487066;ENST00000580180;ENST00000475947;ENST00000481898;ENST00000497774;ENST00000582911;ENST00000584141;ENST00000584926;ENST00000581361;ENST00000581718;ENST00000580770;ENST00000578757;ENST00000492250;ENST00000579473;ENST00000475953;ENST00000583400;ENST00000578380;ENST00000477249;ENST00000470491;ENST00000581913;ENST00000481027;ENST00000460249;ENST00000491009;ENST00000480811;ENST00000483140;ENST00000478103;ENST00000472367;ENST00000483588;ENST00000484836	NA	NA	NA	NA	NA	261.29	252.5	240.5	58.53	71.89	107.74	3.82	1.93	0.01	0.2	up	yes
MSTRG.11493	ZNF287	ENST00000395824;ENST00000395825;ENST00000498796;ENST00000578303;ENST00000448349;ENST00000461555	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 287 [Source:HGNC Symbol;Acc:HGNC:13502]	0.19	0.25	0.61	2.01	2.7	2.18	0.41	-1.3	0.01	0.23	down	yes
MSTRG.11509	FLCN	ENST00000321560;MSTRG.11509.2;ENST00000427497;ENST00000285071;ENST00000577591;ENST00000466317;ENST00000389169;ENST00000480316;ENST00000417064;ENST00000389168;ENST00000389171;ENST00000473853	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0001932(regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007043(cell-cell junction assembly);GO:0010629(negative regulation of gene expression);GO:0010823(negative regulation of mitochondrion organization);GO:0030097(hemopoiesis);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030496(midbody);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031929(TOR signaling);GO:0032006(regulation of TOR signaling);GO:0032007(negative regulation of TOR signaling);GO:0032008(positive regulation of TOR signaling);GO:0032403(protein complex binding);GO:0032465(regulation of cytokinesis);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035065(regulation of histone acetylation);GO:0043065(positive regulation of apoptotic process);GO:0044291(cell-cell contact zone);GO:0045785(positive regulation of cell adhesion);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051898(negative regulation of protein kinase B signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:1900181(negative regulation of protein localization to nucleus);GO:1901723(negative regulation of cell proliferation involved in kidney development);GO:2000506(negative regulation of energy homeostasis);GO:2000973(regulation of pro-B cell differentiation);GO:2001170(negative regulation of ATP biosynthetic process)	05211(Renal cell carcinoma)	NA	NA	folliculin [Source:HGNC Symbol;Acc:HGNC:27310]	7.12	5.82	4.24	1.89	1.2	1.16	2.74	1.45	0.02	0.27	up	yes
MSTRG.1152	GADD45A	ENST00000370986;ENST00000617962;ENST00000370985;ENST00000460575;ENST00000484245	GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000185(activation of MAPKKK activity);GO:0001047(core promoter binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006469(negative regulation of protein kinase activity);GO:0006915(apoptotic process);GO:0006950(response to stress);GO:0007050(cell cycle arrest);GO:0007098(centrosome cycle);GO:0042770(signal transduction in response to DNA damage);GO:0043065(positive regulation of apoptotic process);GO:0046330(positive regulation of JNK cascade);GO:0051726(regulation of cell cycle);GO:0071260(cellular response to mechanical stimulus);GO:0071479(cellular response to ionizing radiation);GO:0071850(mitotic cell cycle arrest);GO:1900745(positive regulation of p38MAPK cascade);GO:2000379(positive regulation of reactive oxygen species metabolic process)	04010(MAPK signaling pathway);04110(Cell cycle);04115(p53 signaling pathway)	NA	NA	"growth arrest and DNA-damage-inducible, alpha [Source:HGNC Symbol;Acc:HGNC:4095]"	169.13	142.96	111.71	21.44	28.63	13.5	6.47	2.69	0.01	0.23	up	yes
MSTRG.11548	SHMT1	ENST00000352886;ENST00000395684;ENST00000316694;MSTRG.11548.2;ENST00000580002;ENST00000354098;ENST00000582352;ENST00000579558;ENST00000582653;ENST00000618902;ENST00000395682;ENST00000583780	GO:0004372(glycine hydroxymethyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006544(glycine metabolic process);GO:0006545(glycine biosynthetic process);GO:0006563(L-serine metabolic process);GO:0006565(L-serine catabolic process);GO:0006766(vitamin metabolic process);GO:0006767(water-soluble vitamin metabolic process);GO:0008242(omega peptidase activity);GO:0008732(L-allo-threonine aldolase activity);GO:0009113(purine nucleobase biosynthetic process);GO:0016597(amino acid binding);GO:0019264(glycine biosynthetic process from serine);GO:0030170(pyridoxal phosphate binding);GO:0034641(cellular nitrogen compound metabolic process);GO:0035999(tetrahydrofolate interconversion);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0044281(small molecule metabolic process);GO:0045329(carnitine biosynthetic process);GO:0046655(folic acid metabolic process);GO:0051262(protein tetramerization);GO:0051289(protein homotetramerization);GO:0070062(extracellular exosome)	"00260(Glycine, serine and threonine metabolism);00460(Cyanoamino acid metabolism);00670(One carbon pool by folate);01100(Metabolic pathways)"	NA	NA	serine hydroxymethyltransferase 1 (soluble) [Source:HGNC Symbol;Acc:HGNC:10850]	1.15	2.05	2.04	9.21	6.18	12.48	0.25	-1.99	0.02	0.26	down	yes
MSTRG.11556	TVP23B	ENST00000307767;ENST00000571018;ENST00000574226;ENST00000575261;ENST00000582288;ENST00000476139;ENST00000581733;ENST00000572845;ENST00000482741	GO:0009306(protein secretion);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0030173(integral component of Golgi membrane)	NA	NA	NA	trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:20399]	6.56	7.14	9.55	2.08	2.06	1.08	2.83	1.5	0.01	0.24	up	yes
MSTRG.11563	FAM83G	ENST00000388995;ENST00000345041;ENST00000399096;ENST00000580115	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0030509(BMP signaling pathway)	NA	NA	NA	"family with sequence similarity 83, member G [Source:HGNC Symbol;Acc:HGNC:32554]"	7.26	6.97	8.54	2.25	3.3	2.2	2.45	1.29	0.01	0.23	up	yes
MSTRG.11650	SGK494	ENST00000481916;ENST00000580377;MSTRG.11650.2;ENST00000582175;ENST00000321765;ENST00000582076;MSTRG.11650.6;ENST00000580676;ENST00000581133;ENST00000580682;ENST00000577259;ENST00000580406;ENST00000578230;ENST00000580083;ENST00000584206;ENST00000580567;ENST00000578479;ENST00000536674;ENST00000584196;ENST00000577790;ENST00000579457;ENST00000578956;ENST00000494272;ENST00000301037;ENST00000581199;ENST00000526073;ENST00000461399;ENST00000527918;ENST00000530121;ENST00000469832;ENST00000527863;ENST00000525510	"GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups)"	NA	NA	NA	uncharacterized serine/threonine-protein kinase SgK494 [Source:EntrezGene;Acc:124923]	1.82	1.36	0.81	25.57	25.11	8.36	0.1	-3.27	0.02	0.26	down	yes
MSTRG.11697	MYO18A	MSTRG.11697.1;MSTRG.11697.2;ENST00000529578;ENST00000533112;ENST00000531253;ENST00000628822;ENST00000527372;ENST00000359450;ENST00000530254;MSTRG.11697.10;ENST00000546105;ENST00000532867;ENST00000527312;ENST00000531438;ENST00000531892;ENST00000529889;ENST00000530557;ENST00000533652;ENST00000532143;ENST00000533399;ENST00000588791;ENST00000590242;ENST00000528564;ENST00000528322;ENST00000585573;ENST00000531267;ENST00000533420;ENST00000590565	GO:0000139(Golgi membrane);GO:0003677(DNA binding);GO:0003774(motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005802(trans-Golgi network);GO:0005856(cytoskeleton);GO:0006259(DNA metabolic process);GO:0007030(Golgi organization);GO:0008094(DNA-dependent ATPase activity);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016459(myosin complex);GO:0016477(cell migration);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0043066(negative regulation of apoptotic process);GO:0043531(ADP binding);GO:0044822(poly(A) RNA binding);GO:0048194(Golgi vesicle budding);GO:0050714(positive regulation of protein secretion);GO:0051015(actin filament binding);GO:0090161(Golgi ribbon formation);GO:0090164(asymmetric Golgi ribbon formation)	NA	NA	NA	myosin XVIIIA [Source:HGNC Symbol;Acc:HGNC:31104]	2.9	3.08	3.31	9.3	7.2	8.67	0.42	-1.26	0	0.17	down	yes
MSTRG.1176	CTH	ENST00000411986;ENST00000370938;ENST00000346806;ENST00000482383	GO:0000096(sulfur amino acid metabolic process);GO:0000098(sulfur amino acid catabolic process);GO:0004123(cystathionine gamma-lyase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006534(cysteine metabolic process);GO:0016846(carbon-sulfur lyase activity);GO:0018272(protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine);GO:0019344(cysteine biosynthetic process);GO:0019346(transsulfuration);GO:0030170(pyridoxal phosphate binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0034641(cellular nitrogen compound metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044281(small molecule metabolic process);GO:0044524(protein sulfhydration);GO:0044540(L-cystine L-cysteine-lyase (deaminating));GO:0047982(homocysteine desulfhydrase activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051289(protein homotetramerization);GO:0070062(extracellular exosome);GO:0070814(hydrogen sulfide biosynthetic process);GO:0080146(L-cysteine desulfhydrase activity);GO:2001234(negative regulation of apoptotic signaling pathway)	"00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism);00450(Selenocompound metabolism);00910(Nitrogen metabolism);01100(Metabolic pathways)"	NA	NA	cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]	3.87	4.65	6.61	1.16	1.03	2.16	2.52	1.33	0.04	0.33	up	yes
MSTRG.11840	SLFN5	ENST00000299977;ENST00000542451;MSTRG.11840.3;ENST00000592325	GO:0005524(ATP binding);GO:0005634(nucleus);GO:0030154(cell differentiation)	NA	NA	NA	schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286]	7.55	12.33	18	2.86	1.97	2.12	3.1	1.63	0.02	0.28	up	yes
MSTRG.11843	SLFN12	MSTRG.11843.1;ENST00000394562;ENST00000304905;ENST00000452764;ENST00000460530;ENST00000479326;ENST00000447040;ENST00000445092	GO:0005524(ATP binding)	NA	NA	NA	schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500]	0.21	0.27	0.37	1.84	1.77	0.77	0.45	-1.14	0.03	0.28	down	yes
MSTRG.11863	TAF15	ENST00000603067;ENST00000605844;MSTRG.11863.3;MSTRG.11863.4;MSTRG.11863.5;ENST00000604879;ENST00000604434;ENST00000603427;ENST00000604360;ENST00000605649;ENST00000603393;ENST00000603777;ENST00000604841;ENST00000605197;ENST00000603346;ENST00000604694;ENST00000603967;ENST00000604195	"GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0044822(poly(A) RNA binding);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	"TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa [Source:HGNC Symbol;Acc:HGNC:11547]"	14.83	15.94	14.43	37.75	39.97	23.72	0.42	-1.26	0.02	0.27	down	yes
MSTRG.1189	ZRANB2	MSTRG.1189.1;MSTRG.1189.2;ENST00000370920;ENST00000610633;ENST00000477096;ENST00000254821;ENST00000487510;ENST00000479947;ENST00000473260;ENST00000611683	"GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006397(mRNA processing);GO:0008270(zinc ion binding);GO:0008380(RNA splicing);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	"zinc finger, RAN-binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:13058]"	4.18	5.49	8.21	14.72	10.73	7.73	0.45	-1.15	0.05	0.34	down	yes
MSTRG.11915	SOCS7	MSTRG.11915.1;ENST00000613678;ENST00000612932;ENST00000617360;ENST00000617765	GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0008150(biological_process);GO:0008286(insulin receptor signaling pathway);GO:0009968(negative regulation of signal transduction);GO:0016567(protein ubiquitination);GO:0017124(SH3 domain binding);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021819(layer formation in cerebral cortex);GO:0021942(radial glia guided migration of Purkinje cell);GO:0035556(intracellular signal transduction);GO:0040008(regulation of growth);GO:0043231(intracellular membrane-bounded organelle);GO:0045444(fat cell differentiation)	NA	NA	NA	suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846]	6.49	7.83	5.72	2.1	3.79	2.91	2.02	1.02	0.05	0.33	up	yes
MSTRG.11944	CACNB1	ENST00000394303;ENST00000622445;ENST00000539338;ENST00000394310;ENST00000344140;ENST00000582544;ENST00000577582;ENST00000536613;ENST00000582877;ENST00000577926	GO:0005245(voltage-gated calcium channel activity);GO:0005515(protein binding);GO:0005891(voltage-gated calcium channel complex);GO:0006612(protein targeting to membrane);GO:0006810(transport);GO:0006816(calcium ion transport);GO:0007268(synaptic transmission);GO:0007411(axon guidance);GO:0007528(neuromuscular junction development);GO:0008331(high voltage-gated calcium channel activity);GO:0016529(sarcoplasmic reticulum);GO:0030315(T-tubule);GO:0070588(calcium ion transmembrane transport);GO:1901385(regulation of voltage-gated calcium channel activity)	04010(MAPK signaling pathway);04260(Cardiac muscle contraction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy)	NA	NA	"calcium channel, voltage-dependent, beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1401]"	3.74	2.86	2.96	0.64	0.64	0.89	2.7	1.43	0	0.1	up	yes
MSTRG.11966	NR1D1	ENST00000246672	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001222(transcription corepressor binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0003714(transcription corepressor activity);GO:0004879(ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005978(glycogen biosynthetic process);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0010498(proteasomal protein catabolic process);GO:0010871(negative regulation of receptor biosynthetic process);GO:0019216(regulation of lipid metabolic process);GO:0020037(heme binding);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0030522(intracellular receptor signaling pathway);GO:0032922(circadian regulation of gene expression);GO:0034144(negative regulation of toll-like receptor 4 signaling pathway);GO:0035947(regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter);GO:0042752(regulation of circadian rhythm);GO:0043197(dendritic spine);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044321(response to leptin);GO:0045598(regulation of fat cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060086(circadian temperature homeostasis);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0061469(regulation of type B pancreatic cell proliferation);GO:0070859(positive regulation of bile acid biosynthetic process);GO:0071222(cellular response to lipopolysaccharide);GO:2000188(regulation of cholesterol homeostasis)"	04710(Circadian rhythm - mammal)	NA	NA	"nuclear receptor subfamily 1, group D, member 1 [Source:HGNC Symbol;Acc:HGNC:7962]"	58.88	36.15	41.1	1.36	1.59	6.01	19.85	4.31	0	0.17	up	yes
MSTRG.11974	CDC6	ENST00000209728;ENST00000580824;ENST00000577249;ENST00000473555;ENST00000582402	GO:0000076(DNA replication checkpoint);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0007067(mitotic nuclear division);GO:0007089(traversing start control point of mitotic cell cycle);GO:0008156(negative regulation of DNA replication);GO:0008285(negative regulation of cell proliferation);GO:0019900(kinase binding);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0032467(positive regulation of cytokinesis);GO:0051233(spindle midzone);GO:0051301(cell division);GO:0051984(positive regulation of chromosome segregation)	04110(Cell cycle)	NA	NA	cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744]	3.37	4.89	2.51	17.94	15.6	9.28	0.24	-2.06	0.01	0.23	down	yes
MSTRG.11984	KRT10	MSTRG.11984.1;ENST00000269576	GO:0005198(structural molecule activity);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005882(intermediate filament);GO:0016020(membrane);GO:0030216(keratinocyte differentiation);GO:0030280(structural constituent of epidermis);GO:0030855(epithelial cell differentiation);GO:0045095(keratin filament);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion)	05150(Staphylococcus aureus infection)	NA	NA	"keratin 10, type I [Source:HGNC Symbol;Acc:HGNC:6413]"	30.02	28.37	23.51	9.99	12.93	9.58	2.47	1.3	0.01	0.23	up	yes
MSTRG.11990	KRT14	ENST00000167586;ENST00000476662	GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005882(intermediate filament);GO:0007568(aging);GO:0008544(epidermis development);GO:0010043(response to zinc ion);GO:0010212(response to ionizing radiation);GO:0030855(epithelial cell differentiation);GO:0031581(hemidesmosome assembly);GO:0034329(cell junction assembly);GO:0042633(hair cycle);GO:0045095(keratin filament);GO:0045110(intermediate filament bundle assembly);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:1990254(keratin filament binding)	NA	NA	NA	"keratin 14, type I [Source:HGNC Symbol;Acc:HGNC:6416]"	0.12	0.34	0.04	2.69	3.03	0.82	0.26	-1.94	0.03	0.29	down	yes
MSTRG.11991	KRT16	ENST00000301653;ENST00000593067;ENST00000588319;ENST00000590990	GO:0002009(morphogenesis of an epithelium);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005856(cytoskeleton);GO:0005882(intermediate filament);GO:0006954(inflammatory response);GO:0007010(cytoskeleton organization);GO:0007568(aging);GO:0008283(cell proliferation);GO:0008544(epidermis development);GO:0030216(keratinocyte differentiation);GO:0030336(negative regulation of cell migration);GO:0031424(keratinization);GO:0042633(hair cycle);GO:0045087(innate immune response);GO:0045104(intermediate filament cytoskeleton organization);GO:0051546(keratinocyte migration);GO:0061436(establishment of skin barrier);GO:0070062(extracellular exosome)	NA	NA	NA	"keratin 16, type I [Source:HGNC Symbol;Acc:HGNC:6423]"	2.43	3.44	1.93	0.25	0.14	0	2.75	1.46	0.01	0.2	up	yes
MSTRG.11993	EIF1	ENST00000462917;ENST00000591776;ENST00000469257;ENST00000482111;ENST00000310837;ENST00000469308;ENST00000586699	"GO:0003743(translation initiation factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0006950(response to stress);GO:0008135(translation factor activity, RNA binding);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249]	291.66	266.7	218.83	103.19	124.61	101.42	2.45	1.29	0.01	0.22	up	yes
MSTRG.12038	TUBG1	ENST00000251413;ENST00000588056;ENST00000591509;ENST00000589688;ENST00000589613	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000212(meiotic spindle organization);GO:0000226(microtubule cytoskeleton organization);GO:0000242(pericentriolar material);GO:0000278(mitotic cell cycle);GO:0000794(condensed nuclear chromosome);GO:0000930(gamma-tubulin complex);GO:0003924(GTPase activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005814(centriole);GO:0005827(polar microtubule);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0005881(cytoplasmic microtubule);GO:0005929(cilium);GO:0006996(organelle organization);GO:0007017(microtubule-based process);GO:0007020(microtubule nucleation);GO:0008152(metabolic process);GO:0031122(cytoplasmic microtubule organization);GO:0031252(cell leading edge);GO:0031513(nonmotile primary cilium);GO:0036064(ciliary basal body);GO:0043234(protein complex);GO:0045177(apical part of cell);GO:0051258(protein polymerization);GO:0055037(recycling endosome)	NA	NA	NA	"tubulin, gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417]"	14.04	13	13	37.97	40.39	28.02	0.38	-1.39	0.01	0.22	down	yes
MSTRG.12040	PLEKHH3	ENST00000591476;ENST00000591196;ENST00000591022;ENST00000456950;ENST00000591490;ENST00000293349;ENST00000592974;ENST00000587627	GO:0005615(extracellular space);GO:0005856(cytoskeleton);GO:0007165(signal transduction)	NA	NA	NA	"pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 [Source:HGNC Symbol;Acc:HGNC:26105]"	4.41	2.91	2.44	0.98	0.98	1.98	2.29	1.19	0.02	0.26	up	yes
MSTRG.12045	EZH1	ENST00000428826;ENST00000415827;MSTRG.12045.3;MSTRG.12045.4;MSTRG.12045.6;ENST00000586714;ENST00000592743;ENST00000588897;ENST00000585893;ENST00000590078;ENST00000586103;ENST00000585550;ENST00000591330;ENST00000590783;ENST00000589846;ENST00000588239;ENST00000585455;ENST00000586935;ENST00000586382;ENST00000586867;ENST00000587179;ENST00000593148;ENST00000586089;ENST00000592492;ENST00000590082	"GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0018024(histone-lysine N-methyltransferase activity);GO:0021766(hippocampus development);GO:0034968(histone lysine methylation);GO:0035098(ESC/E(Z) complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	enhancer of zeste 1 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3526]	8	7.66	6.91	2.23	1.87	2.45	2.75	1.46	0	0.15	up	yes
MSTRG.12052	WNK4	MSTRG.12052.1;ENST00000246914;ENST00000591448;ENST00000592669;ENST00000592072;MSTRG.12052.5	NA	NA	NA	NA	NA	0.32	0.36	1.41	4.48	4.56	4.65	0.29	-1.81	0.02	0.27	down	yes
MSTRG.12101	DUSP3	ENST00000226004;MSTRG.12101.2;ENST00000590753;ENST00000590935;ENST00000590342;ENST00000591618	GO:0000188(inactivation of MAPK activity);GO:0001772(immunological synapse);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0019901(protein kinase binding);GO:0033549(MAP kinase phosphatase activity);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0043409(negative regulation of MAPK cascade);GO:0045087(innate immune response);GO:0045931(positive regulation of mitotic cell cycle);GO:0046329(negative regulation of JNK cascade);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0050868(negative regulation of T cell activation);GO:0051403(stress-activated MAPK cascade);GO:0070062(extracellular exosome);GO:0070373(negative regulation of ERK1 and ERK2 cascade)	04010(MAPK signaling pathway)	NA	NA	dual specificity phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:3069]	12.68	13.16	15.84	6.21	5.55	6.8	2.06	1.04	0.01	0.22	up	yes
MSTRG.12117	UBTF	ENST00000343638;ENST00000302904;MSTRG.12117.3;ENST00000527034;ENST00000533177;ENST00000436088;ENST00000393606;ENST00000526094;ENST00000529383;ENST00000529947;ENST00000531368;ENST00000529373;ENST00000529042;ENST00000530828;ENST00000537550	"GO:0000183(chromatin silencing at rDNA);GO:0001650(fibrillar center);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006338(chromatin remodeling);GO:0006356(regulation of transcription from RNA polymerase I promoter);GO:0006360(transcription from RNA polymerase I promoter);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0010467(gene expression);GO:0040029(regulation of gene expression, epigenetic);GO:0044822(poly(A) RNA binding);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045943(positive regulation of transcription from RNA polymerase I promoter)"	NA	NA	NA	"upstream binding transcription factor, RNA polymerase I [Source:HGNC Symbol;Acc:HGNC:12511]"	7.65	7.77	7.73	17.53	18.97	14.04	0.47	-1.09	0.01	0.2	down	yes
MSTRG.12129	DBF4B	ENST00000393547;MSTRG.12129.2;ENST00000528766;ENST00000528353;ENST00000315005;ENST00000526924;ENST00000526915;ENST00000525140;ENST00000532789;ENST00000527862	GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0007049(cell cycle);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell proliferation);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0016235(aggresome);GO:0019901(protein kinase binding);GO:0030295(protein kinase activator activity);GO:0043231(intracellular membrane-bounded organelle);GO:0045860(positive regulation of protein kinase activity)	NA	NA	NA	DBF4 zinc finger B [Source:HGNC Symbol;Acc:HGNC:17883]	0.55	0.68	0.44	2.63	3.03	1.48	0.42	-1.25	0.02	0.27	down	yes
MSTRG.12135	EFTUD2	ENST00000426333;ENST00000586276;ENST00000592576;ENST00000590367;ENST00000591382;ENST00000590977;ENST00000590124;ENST00000402521;ENST00000589769;ENST00000588340;ENST00000585616;ENST00000587914;ENST00000586654;ENST00000591856;ENST00000587957;ENST00000588374;ENST00000589475;ENST00000586875;ENST00000589825;ENST00000592408;ENST00000592701;ENST00000589211;ENST00000590105	"GO:0000398(mRNA splicing, via spliceosome);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0015030(Cajal body);GO:0016020(membrane);GO:0016607(nuclear speck);GO:0044822(poly(A) RNA binding);GO:0071013(catalytic step 2 spliceosome)"	03040(Spliceosome)	NA	NA	elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858]	7.24	7.8	10.86	22.68	26.28	22.68	0.37	-1.43	0.01	0.23	down	yes
MSTRG.12141	KIF18B	MSTRG.12141.2;MSTRG.12141.1;ENST00000587309;ENST00000593135;ENST00000590129;ENST00000585687	"GO:0000070(mitotic sister chromatid segregation);GO:0000235(astral microtubule);GO:0000278(mitotic cell cycle);GO:0003774(motor activity);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0007018(microtubule-based movement);GO:0007019(microtubule depolymerization);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0019894(kinesin binding);GO:0035371(microtubule plus-end);GO:0051301(cell division);GO:0051302(regulation of cell division)"	NA	NA	NA	kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102]	0.77	0.66	0.43	12.08	13.94	5.3	0.13	-2.93	0.01	0.23	down	yes
MSTRG.12153	HEXIM1	ENST00000332499	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0007507(heart development);GO:0017069(snRNA binding);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901798(positive regulation of signal transduction by p53 class mediator)"	NA	NA	NA	hexamethylene bis-acetamide inducible 1 [Source:HGNC Symbol;Acc:HGNC:24953]	11.28	11.28	12.56	0	0	0	12.65	3.66	0	0.08	up	yes
MSTRG.12156	RP13-890H12.2	ENST00000589796;MSTRG.12156.2;ENST00000589451	NA	NA	NA	NA	NA	1.49	1.17	1.49	0.35	0	0.03	2.06	1.04	0.02	0.25	up	yes
MSTRG.12224	TBKBP1	MSTRG.12224.2;MSTRG.12224.1;ENST00000537587;ENST00000361722;ENST00000622396	GO:0005515(protein binding);GO:0045087(innate immune response)	04622(RIG-I-like receptor signaling pathway)	NA	NA	TBK1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:30140]	5.48	4.46	3.65	1.3	1.28	2.92	2.42	1.28	0.03	0.29	up	yes
MSTRG.12248	NFE2L1	MSTRG.12248.1;ENST00000579889;ENST00000584137;ENST00000362042;ENST00000585291;ENST00000357480;ENST00000585299;ENST00000583060;MSTRG.12248.11;MSTRG.12248.10;MSTRG.12248.12;MSTRG.12248.13;MSTRG.12248.14;MSTRG.12248.15;MSTRG.12248.16;ENST00000361665;ENST00000579481;ENST00000582574;ENST00000585062;ENST00000581441;ENST00000579537;ENST00000583210;ENST00000577411;ENST00000584634;ENST00000582155;ENST00000583378;ENST00000536222;ENST00000577431;ENST00000580037;ENST00000581319	"GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription);GO:0001205(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003712(transcription cofactor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005789(endoplasmic reticulum membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006783(heme biosynthetic process);GO:0006954(inflammatory response);GO:0009653(anatomical structure morphogenesis);GO:0016021(integral component of membrane);GO:0030218(erythrocyte differentiation);GO:0034599(cellular response to oxidative stress);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	"nuclear factor, erythroid 2-like 1 [Source:HGNC Symbol;Acc:HGNC:7781]"	124.61	143.48	132.92	25.01	24.68	44.85	4.67	2.22	0.01	0.23	up	yes
MSTRG.12257	HOXB9	ENST00000311177	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0009952(anterior/posterior pattern specification);GO:0030879(mammary gland development);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048706(embryonic skeletal system development);GO:0060070(canonical Wnt signaling pathway);GO:0060326(cell chemotaxis)"	NA	NA	NA	homeobox B9 [Source:HGNC Symbol;Acc:HGNC:5120]	21.67	26.06	28.11	2.33	1.88	8.49	6.89	2.78	0.04	0.3	up	yes
MSTRG.12289	MIR6165	ENST00000614803	NA	NA	NA	NA	NA	3.61	3.06	2.69	0	0	0	4.31	2.11	0	0.1	up	yes
MSTRG.12300	ITGA3	ENST00000506401;ENST00000505306;ENST00000320031;ENST00000007722;ENST00000508100;ENST00000570989;ENST00000512553;ENST00000505552;ENST00000510809;ENST00000505612;ENST00000506827;ENST00000507771;ENST00000515147;ENST00000504417;ENST00000506437;ENST00000514834	GO:0001764(neuron migration);GO:0001948(glycoprotein binding);GO:0001968(fibronectin binding);GO:0002020(protease binding);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007507(heart development);GO:0007596(blood coagulation);GO:0007613(memory);GO:0008305(integrin complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0010628(positive regulation of gene expression);GO:0010634(positive regulation of epithelial cell migration);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010976(positive regulation of neuron projection development);GO:0016021(integral component of membrane);GO:0016323(basolateral plasma membrane);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0019904(protein domain specific binding);GO:0030111(regulation of Wnt signaling pathway);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0030426(growth cone);GO:0030510(regulation of BMP signaling pathway);GO:0031345(negative regulation of cell projection organization);GO:0031527(filopodium membrane);GO:0034667(integrin alpha3-beta1 complex);GO:0034698(response to gonadotropin);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035640(exploration behavior);GO:0042493(response to drug);GO:0043235(receptor complex);GO:0043236(laminin binding);GO:0043588(skin development);GO:0044708(single-organism behavior);GO:0045202(synapse);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048333(mesodermal cell differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0050900(leukocyte migration);GO:0060076(excitatory synapse);GO:0060135(maternal process involved in female pregnancy);GO:0070062(extracellular exosome);GO:0071438(invadopodium membrane);GO:0071944(cell periphery);GO:0072006(nephron development);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0097060(synaptic membrane);GO:0097062(dendritic spine maintenance);GO:0097205(renal filtration)	04510(Focal adhesion);04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer);05222(Small cell lung cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy)	NA	NA	"integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) [Source:HGNC Symbol;Acc:HGNC:6139]"	170.08	141.33	155.34	70.4	71.99	44.03	2.42	1.28	0.03	0.3	up	yes
MSTRG.12303	.	MSTRG.12303.1	NA	NA	NA	NA	NA	0.75	1.3	2.79	5.76	5.93	7.04	0.32	-1.65	0.04	0.32	down	yes
MSTRG.12320	EME1	ENST00000393271;ENST00000338165;MSTRG.12320.3;MSTRG.12320.4;ENST00000511711;ENST00000511519;ENST00000510007;ENST00000510246;ENST00000513077;ENST00000514211;ENST00000507616	GO:0000790(nuclear chromatin);GO:0003677(DNA binding);GO:0004518(nuclease activity);GO:0004519(endonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005720(nuclear heterochromatin);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0046872(metal ion binding);GO:0072429(response to intra-S DNA damage checkpoint signaling);GO:0090305(nucleic acid phosphodiester bond hydrolysis)	03440(Homologous recombination)	NA	NA	essential meiotic structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:24965]	1.31	1.98	0.94	8.23	9.25	4.64	0.24	-2.04	0.01	0.24	down	yes
MSTRG.12333	ABCC3	MSTRG.12333.1;ENST00000515707;ENST00000513511;ENST00000427699;ENST00000285238;ENST00000502426;ENST00000505699;ENST00000515585;ENST00000513589;ENST00000571855;ENST00000515070;ENST00000503304;ENST00000510633;ENST00000506464;ENST00000513745;ENST00000510891;ENST00000503337;ENST00000508929;ENST00000504586	"GO:0005215(transporter activity);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006810(transport);GO:0008206(bile acid metabolic process);GO:0008514(organic anion transmembrane transporter activity);GO:0015721(bile acid and bile salt transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0044281(small molecule metabolic process);GO:0055085(transmembrane transport)"	02010(ABC transporters);04976(Bile secretion)	NA	NA	"ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:HGNC Symbol;Acc:HGNC:54]"	9.05	7.23	10.87	1.41	0.78	0.89	4.88	2.29	0	0.18	up	yes
MSTRG.12361	TRIM25	MSTRG.12361.1;ENST00000316881;ENST00000573108;ENST00000537230;ENST00000581261;ENST00000572021;ENST00000574234;ENST00000570473;ENST00000570749;ENST00000572550;ENST00000574997	GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0008270(zinc ion binding);GO:0016032(viral process);GO:0016567(protein ubiquitination);GO:0016881(acid-amino acid ligase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0046596(regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051607(defense response to virus);GO:0060333(interferon-gamma-mediated signaling pathway);GO:1902186(regulation of viral release from host cell);GO:1902187(negative regulation of viral release from host cell)	04622(RIG-I-like receptor signaling pathway);05164(Influenza A)	NA	NA	tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932]	17.41	28.25	16.08	3.43	3.85	4.46	3.9	1.96	0.01	0.23	up	yes
MSTRG.1239	FUBP1	MSTRG.1239.1;MSTRG.1239.2;MSTRG.1239.3;ENST00000483894;ENST00000480673;ENST00000474632;ENST00000489495;ENST00000488814;ENST00000492405;ENST00000492724;MSTRG.1239.11;ENST00000294623;ENST00000370768;ENST00000370767;ENST00000487684;ENST00000470287;ENST00000421641	GO:0001205(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003676(nucleic acid binding);GO:0003697(single-stranded DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0044822(poly(A) RNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)	NA	NA	NA	far upstream element (FUSE) binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4004]	7.56	8.93	8.94	28.18	31.44	13.4	0.32	-1.64	0.04	0.31	down	yes
MSTRG.12420	SKA2	ENST00000330137;ENST00000580541;ENST00000578105;ENST00000578519;ENST00000583927;ENST00000581068;ENST00000437036;ENST00000583380;ENST00000583976;MSTRG.12420.10;ENST00000584089	GO:0000278(mitotic cell cycle);GO:0000940(condensed chromosome outer kinetochore);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0008017(microtubule binding);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0051301(cell division)	NA	NA	NA	spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006]	1.37	1.78	1.39	10.65	9.64	2.86	0.23	-2.1	0.04	0.32	down	yes
MSTRG.12424	SMG8	ENST00000262293;MSTRG.12424.1;ENST00000578777;ENST00000577457;ENST00000582995;ENST00000578542;MSTRG.12424.5;ENST00000581182;ENST00000614081;ENST00000580177;MSTRG.12424.9;MSTRG.12424.12;ENST00000582004;ENST00000578922;ENST00000300917;ENST00000580798	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0010467(gene expression);GO:0045859(regulation of protein kinase activity)"	NA	NA	NA	SMG8 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:25551]	2.65	3.56	4.26	13.27	15.72	6.45	0.29	-1.78	0.03	0.29	down	yes
MSTRG.12464	BRIP1	ENST00000259008;ENST00000577598;ENST00000584322;ENST00000579028;ENST00000577913	"GO:0000077(DNA damage checkpoint);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006139(nucleobase-containing compound metabolic process);GO:0006302(double-strand break repair);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008026(ATP-dependent helicase activity);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0031965(nuclear membrane);GO:0032508(DNA duplex unwinding);GO:0044281(small molecule metabolic process);GO:0046872(metal ion binding);GO:0051539(4 iron, 4 sulfur cluster binding)"	NA	NA	NA	BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473]	0.29	0.32	0.19	1.96	1.39	0.54	0.47	-1.08	0.05	0.34	down	yes
MSTRG.125	TPRG1L	ENST00000378344;ENST00000344579	GO:0003674(molecular_function);GO:0008021(synaptic vesicle);GO:0008150(biological_process);GO:0030054(cell junction);GO:0042802(identical protein binding);GO:0070062(extracellular exosome)	NA	NA	NA	tumor protein p63 regulated 1-like [Source:HGNC Symbol;Acc:HGNC:27007]	27.76	25.93	30.08	9.43	10.32	13.24	2.67	1.42	0	0.17	up	yes
MSTRG.12525	ERN1	ENST00000433197;MSTRG.12525.3;MSTRG.12525.2;MSTRG.12525.4;ENST00000583077;ENST00000579249;ENST00000584041;ENST00000583028;ENST00000606895	"GO:0000287(magnesium ion binding);GO:0001935(endothelial cell proliferation);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0004540(ribonuclease activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005637(nuclear inner membrane);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006379(mRNA cleavage);GO:0006397(mRNA processing);GO:0006402(mRNA catabolic process);GO:0006468(protein phosphorylation);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0007050(cell cycle arrest);GO:0007257(activation of JUN kinase activity);GO:0016241(regulation of macroautophagy);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0019899(enzyme binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030969(UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response);GO:0033120(positive regulation of RNA splicing);GO:0034976(response to endoplasmic reticulum stress);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036289(peptidyl-serine autophosphorylation);GO:0036498(IRE1-mediated unfolded protein response);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043531(ADP binding);GO:0044267(cellular protein metabolic process);GO:0046777(protein autophosphorylation);GO:0051879(Hsp90 protein binding);GO:0070054(mRNA splicing, via endonucleolytic cleavage and ligation);GO:0070055(HAC1-type intron splice site recognition and cleavage);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071333(cellular response to glucose stimulus);GO:1900103(positive regulation of endoplasmic reticulum unfolded protein response);GO:1901142(insulin metabolic process);GO:1990332(Ire1 complex);GO:1990579(peptidyl-serine trans-autophosphorylation);GO:1990597(AIP1-IRE1 complex);GO:1990604(IRE1-TRAF2-ASK1 complex);GO:1990630(IRE1-RACK1-PP2A complex)"	04141(Protein processing in endoplasmic reticulum);05010(Alzheimer's disease)	NA	NA	endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449]	6.97	8.53	9.35	0.78	0.47	1.66	4.95	2.31	0.01	0.23	up	yes
MSTRG.12529	MILR1	MSTRG.12529.1;MSTRG.12529.2;MSTRG.12529.3;ENST00000615220;ENST00000619286;ENST00000617071;ENST00000612535;ENST00000616498;ENST00000620304;ENST00000605096	GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0033004(negative regulation of mast cell activation);GO:0042629(mast cell granule);GO:0043303(mast cell degranulation)	NA	NA	NA	mast cell immunoglobulin-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:27570]	7.38	8.95	8.39	2.49	1.92	3.7	2.54	1.34	0.02	0.27	up	yes
MSTRG.12539	FTSJ3	MSTRG.12539.1;ENST00000427159;ENST00000583202;ENST00000583901;ENST00000579831;ENST00000580376;ENST00000580129;ENST00000579569;ENST00000584193;ENST00000580272;ENST00000577263;ENST00000580290;ENST00000582476;ENST00000580295	"GO:0000453(enzyme-directed rRNA 2'-O-methylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0008168(methyltransferase activity);GO:0008649(rRNA methyltransferase activity);GO:0030688(preribosome, small subunit precursor);GO:0031167(rRNA methylation);GO:0032259(methylation);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	FtsJ homolog 3 (E. coli) [Source:HGNC Symbol;Acc:HGNC:17136]	11.34	15.46	23.33	44.97	50.27	40.07	0.32	-1.63	0.02	0.27	down	yes
MSTRG.12556	GNA13	ENST00000439174;ENST00000541118	GO:0001525(angiogenesis);GO:0001569(patterning of blood vessels);GO:0001701(in utero embryonic development);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005834(heterotrimeric G-protein complex);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006928(movement of cell or subcellular component);GO:0007165(signal transduction);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007266(Rho protein signal transduction);GO:0007596(blood coagulation);GO:0008152(metabolic process);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0019001(guanyl nucleotide binding);GO:0030154(cell differentiation);GO:0030168(platelet activation);GO:0030334(regulation of cell migration);GO:0031526(brush border membrane);GO:0031584(activation of phospholipase D activity);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0031702(type 1 angiotensin receptor binding);GO:0031752(D5 dopamine receptor binding);GO:0035556(intracellular signal transduction);GO:0042470(melanosome);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)	NA	NA	NA	"guanine nucleotide binding protein (G protein), alpha 13 [Source:HGNC Symbol;Acc:HGNC:4381]"	4.5	3.9	3.64	0.8	1.25	0.49	2.78	1.48	0.01	0.23	up	yes
MSTRG.12607	WIPI1	ENST00000592645;ENST00000262139;ENST00000589316;ENST00000546360;MSTRG.12607.7;ENST00000590402;ENST00000591744;ENST00000587731;ENST00000591494;ENST00000586815	"GO:0000045(autophagosome assembly);GO:0000139(Golgi membrane);GO:0000407(pre-autophagosomal structure);GO:0000421(autophagosome membrane);GO:0000422(mitochondrion degradation);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006497(protein lipidation);GO:0006914(autophagy);GO:0006995(cellular response to nitrogen starvation);GO:0010008(endosome membrane);GO:0019898(extrinsic component of membrane);GO:0030136(clathrin-coated vesicle);GO:0030331(estrogen receptor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0034045(pre-autophagosomal structure membrane);GO:0034497(protein localization to pre-autophagosomal structure);GO:0036498(IRE1-mediated unfolded protein response);GO:0044267(cellular protein metabolic process);GO:0044804(nucleophagy);GO:0048203(vesicle targeting, trans-Golgi to endosome);GO:0050681(androgen receptor binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding)"	NA	NA	NA	"WD repeat domain, phosphoinositide interacting 1 [Source:HGNC Symbol;Acc:HGNC:25471]"	30.07	29.07	35.31	3.72	2.93	12.28	6.54	2.71	0.03	0.3	up	yes
MSTRG.12640	MAP2K6	ENST00000590474;ENST00000359094;MSTRG.12640.4;ENST00000613873;ENST00000589647;ENST00000591445;ENST00000592348	"GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0001934(positive regulation of protein phosphorylation);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0002931(response to ischemia);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004708(MAP kinase kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006975(DNA damage induced protein phosphorylation);GO:0007050(cell cycle arrest);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019901(protein kinase binding);GO:0022602(ovulation cycle process);GO:0023014(signal transduction by protein phosphorylation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032308(positive regulation of prostaglandin secretion);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0042493(response to drug);GO:0042692(muscle cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0045087(innate immune response);GO:0051149(positive regulation of muscle cell differentiation);GO:0051403(stress-activated MAPK cascade);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0060048(cardiac muscle contraction);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0072709(cellular response to sorbitol)"	NA	NA	NA	mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]	0.3	0.37	0.49	2.04	1.19	1.71	0.49	-1.03	0.01	0.24	down	yes
MSTRG.12672	NUP85	ENST00000583569;ENST00000583948;ENST00000245544;ENST00000582833;ENST00000579324;ENST00000449421;ENST00000577208;ENST00000583548;ENST00000579298;ENST00000581104;ENST00000578830;ENST00000577561;ENST00000579557;ENST00000577645;ENST00000583070;ENST00000580879;ENST00000581335;ENST00000540768;ENST00000582681;ENST00000578294;ENST00000579900;ENST00000578987;ENST00000579838;ENST00000584155	GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005819(spindle);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006935(chemotaxis);GO:0007077(mitotic nuclear envelope disassembly);GO:0007264(small GTPase mediated signal transduction);GO:0008645(hexose transport);GO:0010467(gene expression);GO:0010827(regulation of glucose transport);GO:0015031(protein transport);GO:0015758(glucose transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019221(cytokine-mediated signaling pathway);GO:0030032(lamellipodium assembly);GO:0031080(nuclear pore outer ring);GO:0031965(nuclear membrane);GO:0034605(cellular response to heat);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0048246(macrophage chemotaxis);GO:0051028(mRNA transport);GO:0055085(transmembrane transport);GO:1900034(regulation of cellular response to heat)	03013(RNA transport)	NA	NA	nucleoporin 85kDa [Source:HGNC Symbol;Acc:HGNC:8734]	3.7	3.79	5.81	14.89	17.61	12.74	0.32	-1.64	0.01	0.23	down	yes
MSTRG.12699	WBP2	ENST00000254806;ENST00000626827;ENST00000585462;ENST00000591399;ENST00000587642;ENST00000591831;ENST00000590221;ENST00000586257;ENST00000588373;ENST00000433525;ENST00000589236;ENST00000416574;ENST00000589642;ENST00000587374;ENST00000593002;ENST00000589241;ENST00000590450;ENST00000589834;ENST00000592802	"GO:0000790(nuclear chromatin);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0005515(protein binding);GO:0031490(chromatin DNA binding);GO:0045184(establishment of protein localization);GO:0045815(positive regulation of gene expression, epigenetic);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071391(cellular response to estrogen stimulus);GO:0071442(positive regulation of histone H3-K14 acetylation)"	NA	NA	NA	WW domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:12738]	57.4	52.96	50.17	12.86	11.56	21.78	3.96	1.99	0.01	0.23	up	yes
MSTRG.12733	SNHG16	MSTRG.12733.1;MSTRG.12733.2;ENST00000591956;ENST00000586846;ENST00000587743;ENST00000586942;MSTRG.12733.7;ENST00000493536;ENST00000448136;ENST00000590435;ENST00000587838	NA	NA	NA	NA	NA	52.3	52.8	45.5	21.19	20.59	29.06	2.25	1.17	0.01	0.24	up	yes
MSTRG.12735	ST6GALNAC2	ENST00000589997;MSTRG.12735.2;ENST00000225276;ENST00000585390;ENST00000588920;ENST00000592979;ENST00000588120;ENST00000586520;ENST00000588005;ENST00000585736;ENST00000592508	GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006493(protein O-linked glycosylation);GO:0008373(sialyltransferase activity);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030173(integral component of Golgi membrane);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0097503(sialylation)	NA	NA	NA	"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10867]"	5.18	4.6	4.2	1.36	0.58	1.52	2.77	1.47	0.02	0.26	up	yes
MSTRG.12737	MGAT5B	ENST00000301618;ENST00000569840;ENST00000565675;ENST00000374998;ENST00000428789;ENST00000565043;ENST00000563627;ENST00000563153;ENST00000568598	"GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0006487(protein N-linked glycosylation);GO:0016021(integral component of membrane);GO:0030144(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity);GO:0046872(metal ion binding)"	00510(N-Glycan biosynthesis);00514(Other types of O-glycan biosynthesis);01100(Metabolic pathways)	NA	NA	"mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [Source:HGNC Symbol;Acc:HGNC:24140]"	1.06	1.17	1.29	4.67	4.26	3.19	0.39	-1.34	0	0.17	down	yes
MSTRG.12744	uc_338	ENST00000445478;ENST00000617192;ENST00000303996;ENST00000542934;ENST00000591460;ENST00000397625;ENST00000585429;ENST00000589982;ENST00000613268	NA	NA	NA	NA	NA	23.87	22.4	19.87	8.23	8.74	8.85	2.5	1.32	0	0.13	up	yes
MSTRG.12769	SYNGR2	ENST00000225777;ENST00000585591;ENST00000589183;ENST00000591770;ENST00000588282;ENST00000589168;ENST00000590201;ENST00000592456	GO:0005515(protein binding);GO:0008021(synaptic vesicle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030672(synaptic vesicle membrane);GO:0031594(neuromuscular junction);GO:0070062(extracellular exosome)	NA	NA	NA	synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499]	10.42	7.52	9.79	1.64	1.96	4.62	3.81	1.93	0.01	0.23	up	yes
MSTRG.12771	TK1	ENST00000301634;ENST00000588734;ENST00000590862;ENST00000590430;ENST00000586613;ENST00000592126	GO:0001889(liver development);GO:0004797(thymidine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006206(pyrimidine nucleobase metabolic process);GO:0008270(zinc ion binding);GO:0009157(deoxyribonucleoside monophosphate biosynthetic process);GO:0009165(nucleotide biosynthetic process);GO:0009636(response to toxic substance);GO:0014856(skeletal muscle cell proliferation);GO:0016310(phosphorylation);GO:0019206(nucleoside kinase activity);GO:0031667(response to nutrient levels);GO:0042802(identical protein binding);GO:0043097(pyrimidine nucleoside salvage);GO:0044281(small molecule metabolic process);GO:0046104(thymidine metabolic process);GO:0046688(response to copper ion);GO:0048565(digestive tract development);GO:0051289(protein homotetramerization);GO:0051414(response to cortisol);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0060138(fetal process involved in parturition);GO:0071897(DNA biosynthetic process)	00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);01100(Metabolic pathways)	NA	NA	"thymidine kinase 1, soluble [Source:HGNC Symbol;Acc:HGNC:11830]"	4.39	2.8	2.88	92.57	96.88	42.86	0.06	-4.17	0.01	0.19	down	yes
MSTRG.12775	BIRC5	ENST00000301633;ENST00000350051;ENST00000590925;ENST00000374948;ENST00000590449;ENST00000592734;ENST00000592115;ENST00000586192;ENST00000587746;ENST00000589892	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0000226(microtubule cytoskeleton organization);GO:0000228(nuclear chromosome);GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0000910(cytokinesis);GO:0004842(ubiquitin-protein transferase activity);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005819(spindle);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0005881(cytoplasmic microtubule);GO:0006351(transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0008017(microtubule binding);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell proliferation);GO:0008536(Ran GTPase binding);GO:0009966(regulation of signal transduction);GO:0015631(tubulin binding);GO:0016567(protein ubiquitination);GO:0019899(enzyme binding);GO:0030496(midbody);GO:0031021(interphase microtubule organizing center);GO:0031503(protein complex localization);GO:0031536(positive regulation of exit from mitosis);GO:0031577(spindle checkpoint);GO:0032133(chromosome passenger complex);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045931(positive regulation of mitotic cell cycle);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity);GO:0048037(cofactor binding);GO:0050897(cobalt ion binding);GO:0051087(chaperone binding);GO:0051301(cell division);GO:0051303(establishment of chromosome localization);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0061469(regulation of type B pancreatic cell proliferation);GO:0090307(mitotic spindle assembly);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)"	05200(Pathways in cancer);05210(Colorectal cancer)	NA	NA	baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593]	11.02	7.79	4.13	109.25	146.89	60.93	0.08	-3.6	0.02	0.25	down	yes
MSTRG.12795	USP36	MSTRG.12795.2;MSTRG.12795.4;MSTRG.12795.3;MSTRG.12795.1;ENST00000587010;ENST00000588130;MSTRG.12795.5;ENST00000591052;ENST00000589225;ENST00000587379;MSTRG.12795.11;MSTRG.12795.12;ENST00000592326;MSTRG.12795.14;MSTRG.12795.13;ENST00000592231;ENST00000542802;ENST00000312010;ENST00000588086;ENST00000588467;ENST00000586066;ENST00000590312;ENST00000589254;ENST00000589424;ENST00000590546;ENST00000586531;ENST00000591942;ENST00000586896;ENST00000592907;ENST00000592275;ENST00000587783;ENST00000588365	GO:0004197(cysteine-type endopeptidase activity);GO:0004843(ubiquitin-specific protease activity);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016579(protein deubiquitination);GO:0036459(ubiquitinyl hydrolase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0044822(poly(A) RNA binding);GO:0061136(regulation of proteasomal protein catabolic process);GO:1903146(regulation of mitochondrion degradation);GO:1903955(positive regulation of protein targeting to mitochondrion)	NA	NA	NA	ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]	14.24	17.27	24.35	5	6.45	6.85	2.71	1.44	0.03	0.28	up	yes
MSTRG.12808	CBX4	ENST00000269397;ENST00000448310;ENST00000495122;ENST00000494546	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0003727(single-stranded RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0016568(chromatin modification);GO:0016604(nuclear body);GO:0016607(nuclear speck);GO:0016874(ligase activity);GO:0016925(protein sumoylation);GO:0019789(SUMO transferase activity);GO:0019899(enzyme binding);GO:0031519(PcG protein complex);GO:0032183(SUMO binding);GO:0035064(methylated histone binding);GO:0035102(PRC1 complex);GO:0043066(negative regulation of apoptotic process);GO:0043687(post-translational protein modification);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051219(phosphoprotein binding)"	NA	NA	NA	chromobox homolog 4 [Source:HGNC Symbol;Acc:HGNC:1554]	64.56	40.47	36.48	14.54	15.48	18.05	3.43	1.78	0	0.18	up	yes
MSTRG.12841	CHMP6	ENST00000572525;ENST00000325167;MSTRG.12841.3;ENST00000572778;ENST00000571457	GO:0000815(ESCRT III complex);GO:0000920(cell separation after cytokinesis);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0006997(nucleus organization);GO:0007034(vacuolar transport);GO:0007080(mitotic metaphase plate congression);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0031902(late endosome membrane);GO:0039702(viral budding via host ESCRT complex);GO:0047485(protein N-terminus binding);GO:0061024(membrane organization);GO:0070062(extracellular exosome)	04144(Endocytosis)	NA	NA	charged multivesicular body protein 6 [Source:HGNC Symbol;Acc:HGNC:25675]	2.69	2.51	3.8	7.09	8.74	9.14	0.46	-1.13	0.02	0.25	down	yes
MSTRG.12874	CCDC137	ENST00000329214;ENST00000575223;ENST00000574107;ENST00000574200;ENST00000571916;ENST00000572531	GO:0005730(nucleolus);GO:0044822(poly(A) RNA binding)	NA	NA	NA	coiled-coil domain containing 137 [Source:HGNC Symbol;Acc:HGNC:33451]	12.53	15.67	11.1	23.65	35.63	24.5	0.47	-1.08	0.05	0.33	down	yes
MSTRG.12899	MYADML2	ENST00000329875;ENST00000337943;MSTRG.12899.1;ENST00000403172;ENST00000619204;ENST00000629768;ENST00000577756;ENST00000584848;ENST00000402252;ENST00000582198;ENST00000405481;ENST00000585215;ENST00000577624;ENST00000579698;ENST00000579366;ENST00000581271;ENST00000583564;ENST00000585244;ENST00000409745	GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)	NA	NA	NA	myeloid-associated differentiation marker-like 2 [Source:HGNC Symbol;Acc:HGNC:34548]	41.59	27.76	36.62	8.87	8.66	15.22	3.97	1.99	0	0.18	up	yes
MSTRG.12904	RAC3	ENST00000306688;MSTRG.12904.2;ENST00000583383;ENST00000577638;ENST00000583302;ENST00000581227;ENST00000582083;ENST00000306897;MSTRG.12904.9;MSTRG.12904.10;ENST00000580965;ENST00000584341;ENST00000585014	"GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0012505(endomembrane system);GO:0014041(regulation of neuron maturation);GO:0015031(protein transport);GO:0016020(membrane);GO:0021894(cerebral cortex GABAergic interneuron development);GO:0022604(regulation of cell morphogenesis);GO:0030027(lamellipodium);GO:0030031(cell projection assembly);GO:0030036(actin cytoskeleton organization);GO:0030426(growth cone);GO:0031175(neuron projection development);GO:0031941(filamentous actin);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0035556(intracellular signal transduction);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0048873(homeostasis of number of cells within a tissue);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051932(synaptic transmission, GABAergic);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)"	04010(MAPK signaling pathway);04310(Wnt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04510(Focal adhesion);04520(Adherens junction);04650(Natural killer cell mediated cytotoxicity);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05416(Viral myocarditis)	NA	NA	"ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) [Source:HGNC Symbol;Acc:HGNC:9803]"	4.85	4.09	2.69	8.68	10.72	9.47	0.49	-1.02	0.04	0.31	down	yes
MSTRG.12909	RFNG	ENST00000580793;ENST00000583784;MSTRG.12909.1;ENST00000310496;ENST00000582478;ENST00000580953;MSTRG.12909.7;ENST00000578676;ENST00000429557;ENST00000584838;ENST00000580928;ENST00000584515;ENST00000578356;ENST00000584463	"GO:0003674(molecular_function);GO:0005576(extracellular region);GO:0007389(pattern specification process);GO:0007399(nervous system development);GO:0008152(metabolic process);GO:0009887(organ morphogenesis);GO:0016020(membrane);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030154(cell differentiation);GO:0030173(integral component of Golgi membrane);GO:0032092(positive regulation of protein binding);GO:0033829(O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity);GO:0045746(negative regulation of Notch signaling pathway);GO:0045747(positive regulation of Notch signaling pathway);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)"	00514(Other types of O-glycan biosynthesis);04330(Notch signaling pathway)	NA	NA	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:9974]	21.72	15.3	16.38	3.12	6.02	6.88	4.09	2.03	0	0.17	up	yes
MSTRG.12928	RP13-20L14.6	MSTRG.12928.1;ENST00000579095;ENST00000578344	NA	NA	NA	NA	NA	0.31	0.34	0.38	2.09	1.78	1.06	0.46	-1.11	0.01	0.23	down	yes
MSTRG.12939	RP13-638C3.3	ENST00000575085	NA	NA	NA	NA	NA	2.71	3.11	2.24	0.51	0.8	1.11	2.17	1.12	0.02	0.25	up	yes
MSTRG.12947	METRNL	ENST00000320095;ENST00000570778;ENST00000571814;ENST00000571940;ENST00000574053	GO:0003674(molecular_function);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0009409(response to cold);GO:0014850(response to muscle activity);GO:0045444(fat cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0050873(brown fat cell differentiation);GO:0070062(extracellular exosome);GO:0090336(positive regulation of brown fat cell differentiation);GO:2000507(positive regulation of energy homeostasis)	NA	NA	NA	"meteorin, glial cell differentiation regulator-like [Source:HGNC Symbol;Acc:HGNC:27584]"	23.47	17.27	18.97	3.72	4.61	7.66	4.36	2.12	0	0.17	up	yes
MSTRG.12948	TBCD	ENST00000355528;MSTRG.12948.3;MSTRG.12948.2;ENST00000539345;ENST00000571712;ENST00000576996;ENST00000574801;ENST00000572984;ENST00000574975;ENST00000572953;ENST00000571796;ENST00000574422;ENST00000574818;ENST00000574886;ENST00000570679;ENST00000577051;ENST00000576677;ENST00000575132;ENST00000576603;ENST00000573364;ENST00000576432;ENST00000576691;ENST00000572389;ENST00000572794	GO:0000226(microtubule cytoskeleton organization);GO:0005096(GTPase activator activity);GO:0005488(binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005874(microtubule);GO:0005912(adherens junction);GO:0005923(bicellular tight junction);GO:0006457(protein folding);GO:0007023(post-chaperonin tubulin folding pathway);GO:0010812(negative regulation of cell-substrate adhesion);GO:0016328(lateral plasma membrane);GO:0031115(negative regulation of microtubule polymerization);GO:0034333(adherens junction assembly);GO:0043547(positive regulation of GTPase activity);GO:0044267(cellular protein metabolic process);GO:0048487(beta-tubulin binding);GO:0051084('de novo' posttranslational protein folding);GO:0051087(chaperone binding);GO:0070830(bicellular tight junction assembly);GO:0072668(tubulin complex biogenesis)	NA	NA	NA	tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581]	2.78	2.18	2.75	7.97	9.67	9.21	0.39	-1.35	0	0.12	down	yes
MSTRG.12966	TYMS	ENST00000323274;ENST00000579128;ENST00000323250;ENST00000323224;ENST00000584122;ENST00000581920	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0003729(mRNA binding);GO:0004799(thymidylate synthase activity);GO:0005542(folic acid binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006231(dTMP biosynthetic process);GO:0006235(dTTP biosynthetic process);GO:0007568(aging);GO:0007623(circadian rhythm);GO:0008144(drug binding);GO:0009157(deoxyribonucleoside monophosphate biosynthetic process);GO:0009636(response to toxic substance);GO:0014070(response to organic cyclic compound);GO:0019088(immortalization of host cell by virus);GO:0019860(uracil metabolic process);GO:0031100(organ regeneration);GO:0032259(methylation);GO:0032570(response to progesterone);GO:0033189(response to vitamin A);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0042803(protein homodimerization activity);GO:0044281(small molecule metabolic process);GO:0045471(response to ethanol);GO:0046078(dUMP metabolic process);GO:0046134(pyrimidine nucleoside biosynthetic process);GO:0046653(tetrahydrofolate metabolic process);GO:0046683(response to organophosphorus);GO:0048037(cofactor binding);GO:0048589(developmental growth);GO:0051216(cartilage development);GO:0051384(response to glucocorticoid);GO:0051593(response to folic acid);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0060574(intestinal epithelial cell maturation)	00240(Pyrimidine metabolism);00670(One carbon pool by folate);01100(Metabolic pathways)	NA	NA	thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]	4.28	3.75	2.47	51.88	58.55	39.41	0.09	-3.52	0	0.16	down	yes
MSTRG.13020	PTPRM	ENST00000580170;ENST00000332175;MSTRG.13020.5;ENST00000578916;MSTRG.13020.7;ENST00000578600;ENST00000578698;ENST00000583289;ENST00000577468;ENST00000577827;ENST00000578093;ENST00000580838;ENST00000580949	GO:0001937(negative regulation of endothelial cell proliferation);GO:0004725(protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0006470(protein dephosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007165(signal transduction);GO:0010596(negative regulation of endothelial cell migration);GO:0010842(retina layer formation);GO:0016020(membrane);GO:0016311(dephosphorylation);GO:0016525(negative regulation of angiogenesis);GO:0016791(phosphatase activity);GO:0030027(lamellipodium);GO:0031175(neuron projection development);GO:0031290(retinal ganglion cell axon guidance);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0045296(cadherin binding);GO:0045909(positive regulation of vasodilation);GO:0048471(perinuclear region of cytoplasm)	04514(Cell adhesion molecules (CAMs));04520(Adherens junction)	NA	NA	"protein tyrosine phosphatase, receptor type, M [Source:HGNC Symbol;Acc:HGNC:9675]"	3.76	4.04	3.75	1.1	0.85	1.29	2.35	1.23	0	0.17	up	yes
MSTRG.13075	SPIRE1	ENST00000626255;ENST00000409402;ENST00000410092;ENST00000309836;ENST00000440472;ENST00000453447;ENST00000498803;ENST00000464481;ENST00000588236;ENST00000449797;ENST00000497844;ENST00000462226	GO:0003779(actin binding);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030036(actin cytoskeleton organization);GO:0030659(cytoplasmic vesicle membrane);GO:0032154(cleavage furrow);GO:0036089(cleavage furrow formation);GO:0040038(polar body extrusion after meiotic divisions);GO:0045010(actin nucleation);GO:0046907(intracellular transport);GO:0048193(Golgi vesicle transport);GO:0048471(perinuclear region of cytoplasm);GO:0051295(establishment of meiotic spindle localization);GO:0070649(formin-nucleated actin cable assembly)	04320(Dorso-ventral axis formation)	NA	NA	spire-type actin nucleation factor 1 [Source:HGNC Symbol;Acc:HGNC:30622]	4.99	6.76	8.28	2.35	1	1.42	2.45	1.29	0.02	0.27	up	yes
MSTRG.13090	.	MSTRG.13090.1	NA	NA	NA	NA	NA	1.35	1.26	1.16	0	0.18	0	2.18	1.13	0	0.17	up	yes
MSTRG.13094	SNRPD1	ENST00000300413;ENST00000579618;ENST00000582475	"GO:0000245(spliceosomal complex assembly);GO:0000387(spliceosomal snRNP assembly);GO:0000398(mRNA splicing, via spliceosome);GO:0002230(positive regulation of defense response to virus by host);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005685(U1 snRNP);GO:0005687(U4 snRNP);GO:0005689(U12-type spliceosomal complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030532(small nuclear ribonucleoprotein complex);GO:0034660(ncRNA metabolic process);GO:0034709(methylosome);GO:0034715(pICln-Sm protein complex);GO:0034719(SMN-Sm protein complex);GO:0044822(poly(A) RNA binding);GO:0071013(catalytic step 2 spliceosome);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)"	03040(Spliceosome);05322(Systemic lupus erythematosus)	NA	NA	small nuclear ribonucleoprotein D1 polypeptide 16kDa [Source:HGNC Symbol;Acc:HGNC:11158]	9.75	9.67	9.99	23.93	28.25	14.81	0.43	-1.2	0.04	0.33	down	yes
MSTRG.13124	RIOK3	ENST00000339486;ENST00000584960;ENST00000581585;ENST00000584052;ENST00000581302;ENST00000577501;ENST00000584992;ENST00000584130;ENST00000581339;ENST00000577250;ENST00000581220	"GO:0003824(catalytic activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007059(chromosome segregation);GO:0016772(transferase activity, transferring phosphorus-containing groups)"	NA	NA	NA	RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451]	29.01	32.51	32.69	9.39	8.84	4.59	3.23	1.69	0.01	0.24	up	yes
MSTRG.13127	NPC1	ENST00000591107;ENST00000590723;ENST00000593280;ENST00000586150;MSTRG.13127.5;MSTRG.13127.6;ENST00000269228;ENST00000588867;ENST00000591051;ENST00000587163;ENST00000591955;ENST00000591075;ENST00000540608;ENST00000586718;ENST00000590301	GO:0004872(receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005635(nuclear envelope);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006486(protein glycosylation);GO:0006897(endocytosis);GO:0006914(autophagy);GO:0007041(lysosomal transport);GO:0007165(signal transduction);GO:0007628(adult walking behavior);GO:0008158(hedgehog receptor activity);GO:0008203(cholesterol metabolic process);GO:0008206(bile acid metabolic process);GO:0015248(sterol transporter activity);GO:0015485(cholesterol binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016242(negative regulation of macroautophagy);GO:0030301(cholesterol transport);GO:0031579(membrane raft organization);GO:0031902(late endosome membrane);GO:0031982(vesicle);GO:0033344(cholesterol efflux);GO:0042493(response to drug);GO:0042632(cholesterol homeostasis);GO:0045121(membrane raft);GO:0046686(response to cadmium ion);GO:0046718(viral entry into host cell);GO:0048471(perinuclear region of cytoplasm);GO:0060548(negative regulation of cell death);GO:0070062(extracellular exosome);GO:0071383(cellular response to steroid hormone stimulus);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090150(establishment of protein localization to membrane);GO:2000189(positive regulation of cholesterol homeostasis)	04142(Lysosome)	NA	NA	"Niemann-Pick disease, type C1 [Source:HGNC Symbol;Acc:HGNC:7897]"	14.31	16.92	18.58	4.83	4.23	5.62	2.89	1.53	0	0.18	up	yes
MSTRG.1320	CDC7	ENST00000234626;ENST00000428239;ENST00000497611;ENST00000486509	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000727(double-strand break repair via break-induced replication);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006468(protein phosphorylation);GO:0006909(phagocytosis);GO:0008284(positive regulation of cell proliferation);GO:0008360(regulation of cell shape);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0015630(microtubule cytoskeleton);GO:0016301(kinase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018105(peptidyl-serine phosphorylation);GO:0044770(cell cycle phase transition);GO:0045171(intercellular bridge);GO:0046872(metal ion binding);GO:0051301(cell division)"	04110(Cell cycle)	NA	NA	cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745]	1.61	2.08	1.53	12.48	9.84	2.89	0.23	-2.11	0.05	0.33	down	yes
MSTRG.13294	DYM	MSTRG.13294.1;ENST00000269445;MSTRG.13294.3;ENST00000442713;ENST00000577734;ENST00000583270;ENST00000582399;ENST00000584983;ENST00000418472;ENST00000580615;ENST00000578396;ENST00000578596;ENST00000579058;ENST00000583353;ENST00000577481;ENST00000584977;ENST00000581409;ENST00000582095;ENST00000577836	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0007030(Golgi organization);GO:0019899(enzyme binding);GO:0060348(bone development)	NA	NA	NA	dymeclin [Source:HGNC Symbol;Acc:HGNC:21317]	17.13	18.01	15.37	7.12	6.29	6.01	2.27	1.18	0	0.15	up	yes
MSTRG.13349	RP11-126O1.5	ENST00000588144;MSTRG.13349.2	NA	NA	NA	NA	NA	0.03	0.11	0.01	1.32	0.87	0.6	0.49	-1.04	0.01	0.2	down	yes
MSTRG.13368	TNFRSF11A	ENST00000269485;ENST00000616710;ENST00000617039;ENST00000586569;ENST00000592013;ENST00000587697	GO:0001503(ossification);GO:0002250(adaptive immune response);GO:0002548(monocyte chemotaxis);GO:0004872(receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007275(multicellular organismal development);GO:0008284(positive regulation of cell proliferation);GO:0009314(response to radiation);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016021(integral component of membrane);GO:0019955(cytokine binding);GO:0030316(osteoclast differentiation);GO:0032496(response to lipopolysaccharide);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0034097(response to cytokine);GO:0034612(response to tumor necrosis factor);GO:0043507(positive regulation of JUN kinase activity);GO:0046872(metal ion binding);GO:0048535(lymph node development);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060086(circadian temperature homeostasis);GO:0060749(mammary gland alveolus development);GO:0070555(response to interleukin-1);GO:0071812(positive regulation of fever generation by positive regulation of prostaglandin secretion);GO:0071847(TNFSF11-mediated signaling pathway);GO:0071848(positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling)	04060(Cytokine-cytokine receptor interaction);04380(Osteoclast differentiation);05323(Rheumatoid arthritis)	NA	NA	"tumor necrosis factor receptor superfamily, member 11a, NFKB activator [Source:HGNC Symbol;Acc:HGNC:11908]"	0.18	0.11	0.26	2.51	2.12	1.29	0.37	-1.44	0.01	0.23	down	yes
MSTRG.13376	KDSR	MSTRG.13376.1;MSTRG.13376.2;MSTRG.13376.3;ENST00000406396;ENST00000586791;ENST00000591902;MSTRG.13376.6;ENST00000588089;ENST00000589592;ENST00000326575;ENST00000585750;MSTRG.13376.12;ENST00000592327;ENST00000589530;ENST00000585456;ENST00000587292	GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006665(sphingolipid metabolic process);GO:0006666(3-keto-sphinganine metabolic process);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0030148(sphingolipid biosynthetic process);GO:0044281(small molecule metabolic process);GO:0047560(3-dehydrosphinganine reductase activity);GO:0055114(oxidation-reduction process)	00600(Sphingolipid metabolism);01100(Metabolic pathways)	NA	NA	3-ketodihydrosphingosine reductase [Source:HGNC Symbol;Acc:HGNC:4021]	10.33	6.06	6.39	3.34	3.09	5.67	2.23	1.16	0.02	0.26	up	yes
MSTRG.13412	RTTN	MSTRG.13412.1;ENST00000255674;ENST00000578780;ENST00000583043;ENST00000581161;ENST00000580034;ENST00000579986;ENST00000579021;ENST00000583765;ENST00000581709;ENST00000584659;ENST00000581583	GO:0005488(binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0007368(determination of left/right symmetry);GO:0036064(ciliary basal body);GO:0044782(cilium organization)	NA	NA	NA	rotatin [Source:HGNC Symbol;Acc:HGNC:18654]	1.35	2.05	2.04	6.04	4.88	2.97	0.4	-1.31	0.01	0.22	down	yes
MSTRG.13423	RP11-169F17.1	MSTRG.13423.1;MSTRG.13423.2;MSTRG.13423.3;ENST00000584544;MSTRG.13423.5;MSTRG.13423.6;ENST00000581011;ENST00000581862;ENST00000583405;ENST00000582571;ENST00000584671	NA	NA	NA	NA	NA	6.55	5.45	6.03	1.62	1.73	0.83	2.88	1.53	0.01	0.23	up	yes
MSTRG.13432	TSHZ1	ENST00000322038;MSTRG.13432.2;ENST00000580243;ENST00000560661;ENST00000584217	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0042474(middle ear morphogenesis);GO:0046872(metal ion binding);GO:0060023(soft palate development)"	NA	NA	NA	teashirt zinc finger homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10669]	0.03	2.67	1.38	3.48	2.07	2.12	0.34	-1.54	0.02	0.25	down	yes
MSTRG.13455	RP11-196B3.3	ENST00000621571	NA	NA	NA	NA	NA	0	0.32	0.18	1.62	1.88	1	0.4	-1.32	0.01	0.19	down	yes
MSTRG.13484	SHC2	MSTRG.13484.1;ENST00000264554;ENST00000587423;ENST00000588376;ENST00000590170;ENST00000590222;ENST00000590113	GO:0000187(activation of MAPK activity);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007265(Ras protein signal transduction);GO:0008286(insulin receptor signaling pathway);GO:0019901(protein kinase binding);GO:0030971(receptor tyrosine kinase binding);GO:0035556(intracellular signal transduction);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway)	04012(ErbB signaling pathway);04062(Chemokine signaling pathway);04370(VEGF signaling pathway);04510(Focal adhesion);04650(Natural killer cell mediated cytotoxicity);04722(Neurotrophin signaling pathway);04910(Insulin signaling pathway);05100(Bacterial invasion of epithelial cells);05214(Glioma);05220(Chronic myeloid leukemia)	NA	NA	SHC (Src homology 2 domain containing) transforming protein 2 [Source:HGNC Symbol;Acc:HGNC:29869]	2.4	2.37	2.69	0.45	0.51	1.22	2.28	1.19	0.02	0.26	up	yes
MSTRG.13503	R3HDM4	MSTRG.13503.1;ENST00000361574;ENST00000589428;ENST00000587975;ENST00000591829;ENST00000586080;ENST00000590454;ENST00000589445	GO:0003676(nucleic acid binding);GO:0005634(nucleus)	NA	NA	NA	R3H domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28270]	23.35	19.66	23.67	9.5	10.17	12.39	2.23	1.16	0	0.15	up	yes
MSTRG.13507	ARID3A	MSTRG.13507.1	NA	NA	NA	NA	NA	1.67	0.72	1.28	0	0.13	0.35	2.38	1.25	0	0.12	up	yes
MSTRG.13559	KLF16	MSTRG.13559.1;ENST00000541015;ENST00000250916;ENST00000617223;ENST00000592313	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007212(dopamine receptor signaling pathway);GO:0046872(metal ion binding)"	NA	NA	NA	Kruppel-like factor 16 [Source:HGNC Symbol;Acc:HGNC:16857]	16.79	13.89	13.38	4.77	8.1	7.21	2.45	1.29	0.01	0.22	up	yes
MSTRG.13571	MKNK2	ENST00000589441;ENST00000591601;ENST00000309340;MSTRG.13571.1;MSTRG.13571.6;MSTRG.13571.7;ENST00000587416;ENST00000250896;ENST00000588014;ENST00000586828;ENST00000591588;ENST00000585667;ENST00000586620;ENST00000589509;ENST00000589534	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0007166(cell surface receptor signaling pathway);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0016605(PML body);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018105(peptidyl-serine phosphorylation);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0046777(protein autophosphorylation);GO:0046872(metal ion binding);GO:0071243(cellular response to arsenic-containing substance)"	04010(MAPK signaling pathway);04910(Insulin signaling pathway)	NA	NA	MAP kinase interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:7111]	72.04	47.72	37.91	4.93	4.92	5.54	10.1	3.34	0	0.15	up	yes
MSTRG.13585	GADD45B	ENST00000586759;ENST00000215631;ENST00000592937;ENST00000585359;ENST00000587345;ENST00000587887;ENST00000593043	GO:0000185(activation of MAPKKK activity);GO:0000186(activation of MAPKK activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006469(negative regulation of protein kinase activity);GO:0006915(apoptotic process);GO:0006950(response to stress);GO:0007275(multicellular organismal development);GO:0030154(cell differentiation);GO:0043065(positive regulation of apoptotic process);GO:0046330(positive regulation of JNK cascade);GO:0051726(regulation of cell cycle);GO:1900745(positive regulation of p38MAPK cascade)	04010(MAPK signaling pathway);04110(Cell cycle);04115(p53 signaling pathway)	NA	NA	"growth arrest and DNA-damage-inducible, beta [Source:HGNC Symbol;Acc:HGNC:4096]"	149.14	69.57	73.54	6.15	9.65	5.88	15.19	3.92	0	0.17	up	yes
MSTRG.13597	THOP1	ENST00000307741;ENST00000585673;ENST00000585338;ENST00000586780;ENST00000586677;ENST00000589087;ENST00000591149;ENST00000590533;ENST00000590970;ENST00000587401;ENST00000395212;ENST00000592639;ENST00000587468	GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0042277(peptide binding);GO:0046872(metal ion binding)	04614(Renin-angiotensin system);05143(African trypanosomiasis)	NA	NA	thimet oligopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:11793]	2.3	2.15	3.08	10.43	12.46	7.98	0.3	-1.73	0.01	0.22	down	yes
MSTRG.13600	LMNB2	MSTRG.13600.1;ENST00000215570;ENST00000591871;ENST00000325327;ENST00000490554;ENST00000614319;ENST00000534495	GO:0005198(structural molecule activity);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005637(nuclear inner membrane);GO:0005638(lamin filament);GO:0005882(intermediate filament)	NA	NA	NA	lamin B2 [Source:HGNC Symbol;Acc:HGNC:6638]	17.97	15.82	12.95	63.6	30.58	42.11	0.34	-1.55	0.04	0.33	down	yes
MSTRG.13622	MFSD12	ENST00000615073;MSTRG.13622.2;MSTRG.13622.3;MSTRG.13622.4;MSTRG.13622.5;MSTRG.13622.6;ENST00000585788;MSTRG.13622.7;ENST00000398558;MSTRG.13622.9;MSTRG.13622.8;MSTRG.13622.13;MSTRG.13622.12;ENST00000589157;ENST00000615613;MSTRG.13622.16;MSTRG.13622.17;ENST00000588918;ENST00000355415;ENST00000389395;ENST00000589063;ENST00000589995;ENST00000585814;ENST00000592652;ENST00000591878;ENST00000588626;ENST00000586402	GO:0005765(lysosomal membrane);GO:0006810(transport);GO:0016021(integral component of membrane)	NA	NA	NA	major facilitator superfamily domain containing 12 [Source:HGNC Symbol;Acc:HGNC:28299]	82.32	74.49	63.4	29.91	19.47	41.66	2.71	1.44	0.05	0.34	up	yes
MSTRG.13647	STAP2	ENST00000601956;ENST00000600324;ENST00000594605;ENST00000599736;MSTRG.13647.6;MSTRG.13647.7;ENST00000597593;ENST00000596242;ENST00000602007;ENST00000601179;ENST00000601482	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane)	NA	NA	NA	signal transducing adaptor family member 2 [Source:HGNC Symbol;Acc:HGNC:30430]	2.98	2.72	2.81	0.58	0.72	2	2.28	1.19	0.04	0.32	up	yes
MSTRG.13656	CHAF1A	MSTRG.13656.1;ENST00000301280;ENST00000587580;ENST00000585854;ENST00000585371;ENST00000587368;ENST00000589648	GO:0000790(nuclear chromatin);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006461(protein complex assembly);GO:0007049(cell cycle);GO:0031497(chromatin assembly);GO:0033186(CAF-1 complex);GO:0042802(identical protein binding);GO:0043234(protein complex);GO:0051082(unfolded protein binding);GO:0070087(chromo shadow domain binding)	NA	NA	NA	"chromatin assembly factor 1, subunit A (p150) [Source:HGNC Symbol;Acc:HGNC:1910]"	1.53	2.16	1.49	14.54	15.99	8.84	0.17	-2.59	0	0.17	down	yes
MSTRG.13664	PLIN4	ENST00000301286;ENST00000633942	GO:0005737(cytoplasm);GO:0005811(lipid particle);GO:0005886(plasma membrane)	NA	NA	NA	perilipin 4 [Source:HGNC Symbol;Acc:HGNC:29393]	1.21	1.22	1.8	0.01	0.02	0.18	2.3	1.2	0.01	0.21	up	yes
MSTRG.13666	TNFAIP8L1	ENST00000327473;ENST00000598107;ENST00000536716	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0032007(negative regulation of TOR signaling)	NA	NA	NA	"tumor necrosis factor, alpha-induced protein 8-like 1 [Source:HGNC Symbol;Acc:HGNC:28279]"	1.88	1.42	1.87	4.54	6.23	4.77	0.48	-1.06	0.01	0.22	down	yes
MSTRG.13674	PLIN3	MSTRG.13674.1;ENST00000221957;ENST00000592528;ENST00000589163;ENST00000585479;ENST00000589034;ENST00000589494;ENST00000587462	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005811(lipid particle);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle)	NA	NA	NA	perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893]	7.94	14.62	10.44	24.32	19.87	17.45	0.42	-1.26	0	0.11	down	yes
MSTRG.13677	UHRF1	ENST00000620565;ENST00000624301;ENST00000615884;ENST00000622802;ENST00000616255	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0000791(euchromatin);GO:0000792(heterochromatin);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005657(replication fork);GO:0005720(nuclear heterochromatin);GO:0006281(DNA repair);GO:0006351(transcription, DNA-templated);GO:0007049(cell cycle);GO:0008270(zinc ion binding);GO:0008283(cell proliferation);GO:0008327(methyl-CpG binding);GO:0010216(maintenance of DNA methylation);GO:0010390(histone monoubiquitination);GO:0010467(gene expression);GO:0016363(nuclear matrix);GO:0016574(histone ubiquitination);GO:0016874(ligase activity);GO:0031493(nucleosomal histone binding);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032776(DNA methylation on cytosine);GO:0035064(methylated histone binding);GO:0040029(regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042802(identical protein binding);GO:0044729(hemi-methylated DNA-binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)"	NA	NA	NA	ubiquitin-like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556]	0.75	0.9	0.53	13.91	13.81	7.06	0.11	-3.14	0	0.18	down	yes
MSTRG.13689	RPL36	MSTRG.13689.1;ENST00000579649;ENST00000577257;ENST00000577917;ENST00000581893;ENST00000582346;ENST00000301382;ENST00000581773;ENST00000423665;ENST00000584904;ENST00000583928;ENST00000579562;ENST00000342970;ENST00000422535;ENST00000578167;ENST00000577701;ENST00000581521;ENST00000339423;ENST00000578832;ENST00000577920;ENST00000577222;ENST00000578046;ENST00000581423;ENST00000347512;ENST00000582463;ENST00000590786;ENST00000579446;ENST00000394580	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding)"	03010(Ribosome)	NA	NA	ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:13631]	89.19	80.03	81.62	31.42	52.35	70.3	2.17	1.12	0.05	0.33	up	yes
MSTRG.13714	ALKBH7	ENST00000245812;MSTRG.13714.2;ENST00000596657;ENST00000599849	GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006631(fatty acid metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0010883(regulation of lipid storage);GO:0046872(metal ion binding);GO:0051213(dioxygenase activity);GO:0055114(oxidation-reduction process);GO:1902445(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)	NA	NA	NA	"alkB, alkylation repair homolog 7 (E. coli) [Source:HGNC Symbol;Acc:HGNC:21306]"	11.25	7.95	9.61	2.85	3.97	7.64	2.61	1.38	0.02	0.27	up	yes
MSTRG.13719	KHSRP	MSTRG.13719.2;MSTRG.13719.3;MSTRG.13719.4;MSTRG.13719.5;MSTRG.13719.6;MSTRG.13719.7;ENST00000398148;ENST00000594745;ENST00000597656;ENST00000595223;ENST00000594496;ENST00000600480;ENST00000599642;ENST00000579148;ENST00000595112;ENST00000599395;ENST00000595548;ENST00000595258;ENST00000597704	"GO:0000375(RNA splicing, via transesterification reactions);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006397(mRNA processing);GO:0006402(mRNA catabolic process);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0010494(cytoplasmic stress granule);GO:0016020(membrane);GO:0044822(poly(A) RNA binding);GO:0051028(mRNA transport);GO:2000628(regulation of miRNA metabolic process)"	NA	NA	NA	KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:HGNC:6316]	21.45	21.02	22.51	45.03	51.25	43.15	0.48	-1.06	0	0.17	down	yes
MSTRG.13720	TNFSF9	MSTRG.13720.1;ENST00000245817	GO:0005102(receptor binding);GO:0005125(cytokine activity);GO:0005164(tumor necrosis factor receptor binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0008283(cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032729(positive regulation of interferon-gamma production);GO:0032735(positive regulation of interleukin-12 production);GO:0032755(positive regulation of interleukin-6 production);GO:0032813(tumor necrosis factor receptor superfamily binding);GO:0042104(positive regulation of activated T cell proliferation);GO:0042127(regulation of cell proliferation);GO:0043011(myeloid dendritic cell differentiation);GO:0045585(positive regulation of cytotoxic T cell differentiation)	04060(Cytokine-cytokine receptor interaction)	NA	NA	"tumor necrosis factor (ligand) superfamily, member 9 [Source:HGNC Symbol;Acc:HGNC:11939]"	7.32	2.69	7.57	0.35	0.45	0.03	6.2	2.63	0.02	0.25	up	yes
MSTRG.13728	TRIP10	ENST00000600428;ENST00000596543;ENST00000313285;ENST00000600677;ENST00000313244;ENST00000595305;ENST00000596758;ENST00000600491;ENST00000596078;ENST00000596673;ENST00000595319;ENST00000601303;ENST00000598843	GO:0001891(phagocytic cup);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005938(cell cortex);GO:0006897(endocytosis);GO:0007154(cell communication);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008289(lipid binding);GO:0030036(actin cytoskeleton organization);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle);GO:0048471(perinuclear region of cytoplasm);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0070062(extracellular exosome)	04910(Insulin signaling pathway)	NA	NA	thyroid hormone receptor interactor 10 [Source:HGNC Symbol;Acc:HGNC:12304]	33.49	32.12	34.73	8.81	10.37	15.67	3.23	1.69	0.01	0.21	up	yes
MSTRG.13732	GPR108	ENST00000264080;ENST00000537722;ENST00000594500;ENST00000598626;ENST00000595908;ENST00000430424;ENST00000597706;ENST00000598955;ENST00000600773;ENST00000597298;ENST00000598052;ENST00000601716;ENST00000595108;ENST00000595620;ENST00000601402;ENST00000597043	GO:0016021(integral component of membrane)	NA	NA	NA	G protein-coupled receptor 108 [Source:HGNC Symbol;Acc:HGNC:17829]	23.73	22.41	24.16	10.76	11.02	17.23	2.01	1.01	0.03	0.28	up	yes
MSTRG.13759	SNAPC2	ENST00000221573;ENST00000595637;ENST00000593598;ENST00000595035;ENST00000597584;ENST00000596520	"GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006383(transcription from RNA polymerase III promoter);GO:0009301(snRNA transcription);GO:0010467(gene expression)"	NA	NA	NA	"small nuclear RNA activating complex, polypeptide 2, 45kDa [Source:HGNC Symbol;Acc:HGNC:11135]"	34.4	26.91	24.83	9.87	11.67	14.31	2.74	1.45	0	0.16	up	yes
MSTRG.13782	HNRNPM	ENST00000348943;MSTRG.13782.2;ENST00000597813;MSTRG.13782.3;MSTRG.13782.5;ENST00000325495;ENST00000600092;ENST00000600806;MSTRG.13782.9;ENST00000620401;ENST00000594907;ENST00000601645;ENST00000593293;ENST00000597270;ENST00000597081;ENST00000598603;ENST00000596295;ENST00000598999;ENST00000602219	"GO:0000166(nucleotide binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005730(nucleolus);GO:0005887(integral component of plasma membrane);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0019904(protein domain specific binding);GO:0031012(extracellular matrix);GO:0042382(paraspeckles);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome);GO:0071013(catalytic step 2 spliceosome)"	03040(Spliceosome)	NA	NA	heterogeneous nuclear ribonucleoprotein M [Source:HGNC Symbol;Acc:HGNC:5046]	11.01	11.94	17.85	62.92	61.81	38.63	0.23	-2.14	0.01	0.23	down	yes
MSTRG.13822	S1PR2	ENST00000586588;MSTRG.13822.1;ENST00000592705;ENST00000340748;MSTRG.13822.4;ENST00000591798;ENST00000588913;ENST00000359526;ENST00000589294;ENST00000587197;ENST00000589538;ENST00000589351;ENST00000593049;ENST00000587604;ENST00000589091;ENST00000591239;ENST00000586667;ENST00000586799;ENST00000585843;ENST00000589349;ENST00000591764;ENST00000585920;ENST00000586988;ENST00000588952;ENST00000588118;ENST00000592342;ENST00000592054;ENST00000590619;ENST00000586086;ENST00000590320	GO:0000187(activation of MAPK activity);GO:0001664(G-protein coupled receptor binding);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0004930(G-protein coupled receptor activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0008289(lipid binding);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0016021(integral component of membrane);GO:0031532(actin cytoskeleton reorganization);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0046847(filopodium assembly);GO:0090394(negative regulation of excitatory postsynaptic membrane potential);GO:1903142(positive regulation of establishment of endothelial barrier)	NA	NA	NA	sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169]	6.19	6.98	7.99	28.63	27.98	17.64	0.27	-1.87	0.01	0.2	down	yes
MSTRG.13841	KRI1	MSTRG.13841.1;ENST00000312962;ENST00000536689;ENST00000537363;ENST00000618579;ENST00000478863;ENST00000612875;ENST00000537433;ENST00000543842;ENST00000539027;MSTRG.13841.10;ENST00000536714;ENST00000432197;ENST00000546063;ENST00000544397	GO:0005730(nucleolus);GO:0044822(poly(A) RNA binding)	NA	NA	NA	KRI1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:25769]	3.74	4.16	6.62	11.42	11.52	9.69	0.45	-1.17	0.03	0.29	down	yes
MSTRG.13855	YIPF2	MSTRG.13855.1;MSTRG.13855.2;ENST00000253031;ENST00000586748;ENST00000592646;ENST00000589971;ENST00000591872;ENST00000590329;ENST00000586575;ENST00000587943;ENST00000588347;ENST00000585858;ENST00000588962;ENST00000592505	GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030133(transport vesicle)	NA	NA	NA	"Yip1 domain family, member 2 [Source:HGNC Symbol;Acc:HGNC:28476]"	19.45	21.3	20.96	4.19	5.06	6.42	3.72	1.9	0	0.17	up	yes
MSTRG.13861	SPC24	ENST00000585567;ENST00000592540;ENST00000591396;ENST00000592967;ENST00000423327;ENST00000586708;ENST00000585486	GO:0000278(mitotic cell cycle);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0031262(Ndc80 complex);GO:0051301(cell division)	NA	NA	NA	"SPC24, NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:26913]"	0.79	1.07	0.47	12.89	13.97	5.26	0.13	-2.95	0.01	0.23	down	yes
MSTRG.13863	DOCK6	MSTRG.13863.1;ENST00000586702;ENST00000294618;ENST00000587656;ENST00000588666;ENST00000592463;ENST00000588429;ENST00000592403;ENST00000590680;ENST00000591750;ENST00000585609;ENST00000586482;ENST00000587572	GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007264(small GTPase mediated signal transduction);GO:0007596(blood coagulation);GO:0043547(positive regulation of GTPase activity);GO:0048471(perinuclear region of cytoplasm)	NA	NA	NA	dedicator of cytokinesis 6 [Source:HGNC Symbol;Acc:HGNC:19189]	2.75	2.65	2.42	0.35	0.34	1.19	2.59	1.37	0.02	0.26	up	yes
MSTRG.13933	C19orf43	ENST00000591254;ENST00000592273;ENST00000242784;ENST00000588213;ENST00000589590	NA	NA	NA	NA	chromosome 19 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:28424]	31.83	26.05	24.8	64.9	75.05	80.89	0.43	-1.2	0	0.13	down	yes
MSTRG.13943	RNASEH2A	ENST00000221486;ENST00000593017;ENST00000590121;ENST00000590279	"GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0004540(ribonuclease activity);GO:0005634(nucleus);GO:0006260(DNA replication);GO:0006298(mismatch repair);GO:0006401(RNA catabolic process);GO:0016070(RNA metabolic process);GO:0032299(ribonuclease H2 complex);GO:0043137(DNA replication, removal of RNA primer);GO:0046872(metal ion binding);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)"	03030(DNA replication)	NA	NA	"ribonuclease H2, subunit A [Source:HGNC Symbol;Acc:HGNC:18518]"	5	4.9	4.5	26.09	37.44	15.7	0.21	-2.29	0.02	0.26	down	yes
MSTRG.13951	SYCE2	ENST00000293695;ENST00000592819;ENST00000591229	GO:0000801(central element);GO:0005515(protein binding);GO:0007130(synaptonemal complex assembly);GO:0051301(cell division)	NA	NA	NA	synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411]	0.22	0.57	0.19	1.36	1.86	1.01	0.49	-1.01	0.02	0.27	down	yes
MSTRG.13966	NACC1	MSTRG.13966.1;ENST00000292431	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0008284(positive regulation of cell proliferation);GO:0016604(nuclear body);GO:0030054(cell junction);GO:0043231(intracellular membrane-bounded organelle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051260(protein homooligomerization)"	NA	NA	NA	"nucleus accumbens associated 1, BEN and BTB (POZ) domain containing [Source:HGNC Symbol;Acc:HGNC:20967]"	10.1	10.54	9.87	25.57	23.96	23.36	0.43	-1.23	0	0.08	down	yes
MSTRG.13996	ASF1B	ENST00000263382;ENST00000592798;ENST00000590835;ENST00000589468;ENST00000474890	"GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006333(chromatin assembly or disassembly);GO:0006334(nucleosome assembly);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007275(multicellular organismal development);GO:0007283(spermatogenesis);GO:0016568(chromatin modification);GO:0030154(cell differentiation);GO:0042393(histone binding);GO:0043234(protein complex)"	NA	NA	NA	anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996]	1.48	1.02	0.77	28.62	29.85	17.17	0.08	-3.67	0	0.17	down	yes
MSTRG.14001	ADGRE5	MSTRG.14001.2;ENST00000358600;MSTRG.14001.4;ENST00000587535;ENST00000587606;ENST00000591080;ENST00000357355;ENST00000592261;ENST00000242786;ENST00000591737;ENST00000593028;ENST00000590567;ENST00000592341;ENST00000591565	GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006928(movement of cell or subcellular component);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	NA	NA	NA	adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]	25.28	22.19	23.15	10.21	12.64	14.36	2.09	1.07	0	0.16	up	yes
MSTRG.14002	DDX39A	ENST00000590626;MSTRG.14002.2;ENST00000587730;ENST00000324340;ENST00000589318;ENST00000588692;ENST00000242776;ENST00000592927;ENST00000592391;ENST00000588542;ENST00000454233;ENST00000589675;ENST00000593026;ENST00000590315;ENST00000590556;ENST00000590260;ENST00000586558;ENST00000590239;ENST00000586993;ENST00000592632;ENST00000593008;ENST00000591275;ENST00000590696	"GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006406(mRNA export from nucleus);GO:0006974(cellular response to DNA damage stimulus);GO:0010468(regulation of gene expression);GO:0010501(RNA secondary structure unwinding);GO:0016020(membrane);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A [Source:HGNC Symbol;Acc:HGNC:17821]	7.68	5.3	11.84	42.32	52.72	22.84	0.22	-2.16	0.05	0.33	down	yes
MSTRG.14003	PKN1	MSTRG.14003.1;ENST00000585619;ENST00000585839;ENST00000242783;ENST00000586557;ENST00000587429;ENST00000590097;ENST00000342216;ENST00000592794;ENST00000588200;ENST00000586900;ENST00000586237;ENST00000587215;ENST00000591461;ENST00000586039;ENST00000592960	"GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001933(negative regulation of protein phosphorylation);GO:0002634(regulation of germinal center formation);GO:0002637(regulation of immunoglobulin production);GO:0003014(renal system process);GO:0003682(chromatin binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004697(protein kinase C activity);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:0006972(hyperosmotic response);GO:0007165(signal transduction);GO:0007257(activation of JUN kinase activity);GO:0007264(small GTPase mediated signal transduction);GO:0010631(epithelial cell migration);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0017049(GTP-Rho binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0030496(midbody);GO:0030889(negative regulation of B cell proliferation);GO:0032154(cleavage furrow);GO:0035402(histone kinase activity (H3-T11 specific));GO:0035407(histone H3-T11 phosphorylation);GO:0042393(histone binding);GO:0042826(histone deacetylase binding);GO:0043234(protein complex);GO:0048365(Rac GTPase binding);GO:0048536(spleen development);GO:0050681(androgen receptor binding);GO:2000145(regulation of cell motility)"	NA	NA	NA	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405]	30.65	26.1	34.59	8.47	9.62	13.02	3.22	1.69	0	0.18	up	yes
MSTRG.14013	ADGRE3	MSTRG.14013.1	NA	NA	NA	NA	NA	1.41	1.6	0.85	0	0	0	2.23	1.16	0.01	0.23	up	yes
MSTRG.14020	BRD4	MSTRG.14020.4;MSTRG.14020.3;MSTRG.14020.2;ENST00000594066;MSTRG.14020.6;MSTRG.14020.7;MSTRG.14020.10;MSTRG.14020.9;ENST00000360016;ENST00000595926;ENST00000594841;ENST00000602230;ENST00000594842;MSTRG.14020.16;ENST00000597315;ENST00000601071;ENST00000630599	"GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0000794(condensed nuclear chromosome);GO:0001833(inner cell mass cell proliferation);GO:0002039(p53 binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006974(cellular response to DNA damage stimulus);GO:0007059(chromosome segregation);GO:0008024(positive transcription elongation factor complex b);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0016032(viral process);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043388(positive regulation of DNA binding);GO:0043983(histone H4-K12 acetylation);GO:0044154(histone H3-K14 acetylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050727(regulation of inflammatory response);GO:0070577(lysine-acetylated histone binding);GO:1901407(regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:2000002(negative regulation of DNA damage checkpoint)"	NA	NA	NA	bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]	12.3	10.16	9.38	3.94	4.22	4.14	2.45	1.29	0	0.14	up	yes
MSTRG.14033	HSH2D	ENST00000300935;ENST00000590899;ENST00000588105;ENST00000587156;ENST00000586682;ENST00000589697;ENST00000592971;ENST00000616070	GO:0002903(negative regulation of B cell apoptotic process);GO:0005070(SH3/SH2 adaptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0009967(positive regulation of signal transduction);GO:0042110(T cell activation);GO:0051902(negative regulation of mitochondrial depolarization)	NA	NA	NA	hematopoietic SH2 domain containing [Source:HGNC Symbol;Acc:HGNC:24920]	2.71	3.24	3.8	9.3	9.23	4.98	0.41	-1.3	0.03	0.28	down	yes
MSTRG.14059	SIN3B	ENST00000248054;ENST00000596802;ENST00000379803;ENST00000596638;ENST00000599880;ENST00000595541;ENST00000594372;ENST00000595900;ENST00000602204;ENST00000595049;ENST00000601141	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000785(chromatin);GO:0000805(X chromosome);GO:0000806(Y chromosome);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0001741(XY body);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0004407(histone deacetylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007519(skeletal muscle tissue development);GO:0016575(histone deacetylation);GO:0016580(Sin3 complex);GO:0030849(autosome);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048738(cardiac muscle tissue development)"	NA	NA	NA	SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]	8.29	7.61	9.16	3.51	3.73	4.8	2.03	1.02	0.01	0.2	up	yes
MSTRG.1406	RTCA	MSTRG.1406.1;MSTRG.1406.2;ENST00000370128;ENST00000498617;MSTRG.1406.5;ENST00000483474;ENST00000260563;ENST00000370126	GO:0003723(RNA binding);GO:0003824(catalytic activity);GO:0003963(RNA-3'-phosphate cyclase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006396(RNA processing);GO:0044822(poly(A) RNA binding)	NA	NA	NA	RNA 3'-terminal phosphate cyclase [Source:HGNC Symbol;Acc:HGNC:17981]	27.63	27.08	20.89	11.52	10.98	6.54	2.25	1.17	0.05	0.33	up	yes
MSTRG.14061	HAUS8	ENST00000253669;ENST00000597917;ENST00000448593;ENST00000593360;ENST00000598517;ENST00000597479;ENST00000601564;ENST00000595958	GO:0000922(spindle pole);GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005874(microtubule);GO:0007067(mitotic nuclear division);GO:0051225(spindle assembly);GO:0051297(centrosome organization);GO:0051301(cell division);GO:0070652(HAUS complex)	NA	NA	NA	"HAUS augmin-like complex, subunit 8 [Source:HGNC Symbol;Acc:HGNC:30532]"	0.44	0.54	0.6	3.57	4.26	1.84	0.33	-1.61	0.02	0.26	down	yes
MSTRG.14068	USE1	ENST00000601662;ENST00000263897;ENST00000600970;ENST00000595101;ENST00000596136;ENST00000601592;ENST00000594724;ENST00000445667;ENST00000593597;ENST00000594399	GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007029(endoplasmic reticulum organization);GO:0007041(lysosomal transport);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0030163(protein catabolic process);GO:0032940(secretion by cell);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0071786(endoplasmic reticulum tubular network organization)	04130(SNARE interactions in vesicular transport)	NA	NA	unconventional SNARE in the ER 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:30882]	10.68	10.49	11.67	4.36	5.78	6.7	2.02	1.01	0.01	0.23	up	yes
MSTRG.14077	ANO8	ENST00000597643;ENST00000159087;MSTRG.14077.1;MSTRG.14077.4;ENST00000600711	GO:0005229(intracellular calcium activated chloride channel activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0006821(chloride transport);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport);GO:1902476(chloride transmembrane transport)	NA	NA	NA	anoctamin 8 [Source:HGNC Symbol;Acc:HGNC:29329]	5.37	5.77	3.82	1.62	1.35	2.01	2.28	1.19	0.02	0.26	up	yes
MSTRG.14112	PGPEP1	MSTRG.14112.1;ENST00000269919;ENST00000604499;ENST00000595066;MSTRG.14112.5;ENST00000252813;ENST00000596962;ENST00000600283;ENST00000597431;ENST00000597663;ENST00000595552	GO:0005829(cytosol);GO:0006508(proteolysis);GO:0008234(cysteine-type peptidase activity);GO:0016920(pyroglutamyl-peptidase activity)	NA	NA	NA	pyroglutamyl-peptidase I [Source:HGNC Symbol;Acc:HGNC:13568]	6.51	6.53	7.48	1.09	1.57	2.18	3.37	1.75	0	0.18	up	yes
MSTRG.14127	AC005253.2	ENST00000597411	NA	NA	NA	NA	NA	5.57	4.65	4.64	1.53	1.34	2.56	2.45	1.29	0.01	0.23	up	yes
MSTRG.1420	COL11A1	ENST00000370096;ENST00000358392;ENST00000353414;ENST00000470170;ENST00000512756;ENST00000465209;ENST00000461720;ENST00000475980;ENST00000427239;ENST00000447608	"GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0002063(chondrocyte development);GO:0003007(heart morphogenesis);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005581(collagen trimer);GO:0005592(collagen type XI trimer);GO:0005788(endoplasmic reticulum lumen);GO:0006029(proteoglycan metabolic process);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0030574(collagen catabolic process);GO:0030674(protein binding, bridging);GO:0031012(extracellular matrix);GO:0035987(endodermal cell differentiation);GO:0035989(tendon development);GO:0042472(inner ear morphogenesis);GO:0046872(metal ion binding);GO:0048704(embryonic skeletal system morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0050840(extracellular matrix binding);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0051216(cartilage development);GO:0055010(ventricular cardiac muscle tissue morphogenesis)"	04510(Focal adhesion);04512(ECM-receptor interaction);04974(Protein digestion and absorption);05146(Amoebiasis)	NA	NA	"collagen, type XI, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2186]"	19.28	22.36	8.6	66.45	49.97	54.67	0.27	-1.91	0.05	0.34	down	yes
MSTRG.14260	LINC00662	ENST00000588027;MSTRG.14260.2;ENST00000590677;MSTRG.14260.4;MSTRG.14260.5;ENST00000588150;MSTRG.14260.7;MSTRG.14260.10;MSTRG.14260.9;MSTRG.14260.8;MSTRG.14260.11;ENST00000561521;ENST00000586248;ENST00000586954;ENST00000591338;ENST00000590523;ENST00000591458	NA	NA	NA	NA	NA	2.78	4.03	2.29	0.59	0.51	0.44	2.35	1.23	0.01	0.23	up	yes
MSTRG.14277	CCNE1	ENST00000262643;ENST00000575243;ENST00000444983;ENST00000357943;ENST00000586912;ENST00000576532;ENST00000574121	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0001547(antral ovarian follicle growth);GO:0001889(liver development);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006270(DNA replication initiation);GO:0006468(protein phosphorylation);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0014074(response to purine-containing compound);GO:0016055(Wnt signaling pathway);GO:0016301(kinase activity);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0019901(protein kinase binding);GO:0030521(androgen receptor signaling pathway);GO:0031100(organ regeneration);GO:0031670(cellular response to nutrient);GO:0032355(response to estradiol);GO:0032403(protein complex binding);GO:0032570(response to progesterone);GO:0033197(response to vitamin E);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0045471(response to ethanol);GO:0045597(positive regulation of cell differentiation);GO:0045859(regulation of protein kinase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048545(response to steroid hormone);GO:0050681(androgen receptor binding);GO:0051301(cell division);GO:0051412(response to corticosterone);GO:0051597(response to methylmercury);GO:0051726(regulation of cell cycle)"	04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);05162(Measles);05200(Pathways in cancer);05215(Prostate cancer);05222(Small cell lung cancer)	NA	NA	cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589]	1.74	2.88	1.54	4.9	4.91	5.36	0.45	-1.15	0.02	0.26	down	yes
MSTRG.14308	CEBPG	ENST00000284000;ENST00000585933	"GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001889(liver development);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0016071(mRNA metabolic process);GO:0030183(B cell differentiation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0043353(enucleate erythrocyte differentiation);GO:0043388(positive regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043565(sequence-specific DNA binding);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0045739(positive regulation of DNA repair);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity)"	05152(Tuberculosis)	NA	NA	"CCAAT/enhancer binding protein (C/EBP), gamma [Source:HGNC Symbol;Acc:HGNC:1837]"	30.85	34.49	32.42	0.31	7.54	3.23	12.96	3.7	0.04	0.31	up	yes
MSTRG.14344	LSR	ENST00000602122;ENST00000621372;ENST00000602044;MSTRG.14344.13;ENST00000602262;ENST00000597446	GO:0001889(liver development);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0016021(integral component of membrane);GO:0019216(regulation of lipid metabolic process);GO:0034361(very-low-density lipoprotein particle);GO:0034362(low-density lipoprotein particle);GO:0042627(chylomicron);GO:0070062(extracellular exosome)	NA	NA	NA	lipolysis stimulated lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:29572]	0.21	0.22	0.25	2.01	1.54	1.96	0.42	-1.25	0	0.15	down	yes
MSTRG.14459	NFKBIB	ENST00000392079;ENST00000572515;MSTRG.14459.4;ENST00000575359;ENST00000509705;ENST00000313582	"GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0003713(transcription coactivator activity);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0007165(signal transduction);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0032481(positive regulation of type I interferon production);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0045087(innate immune response);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0071222(cellular response to lipopolysaccharide)"	04062(Chemokine signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04722(Neurotrophin signaling pathway);04920(Adipocytokine signaling pathway);05131(Shigellosis);05140(Leishmaniasis);05145(Toxoplasmosis);05162(Measles);05164(Influenza A)	NA	NA	"nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta [Source:HGNC Symbol;Acc:HGNC:7798]"	13.34	11.16	12.22	5.05	4.34	4.45	2.42	1.27	0	0.15	up	yes
MSTRG.14470	SAMD4B	ENST00000602243;MSTRG.14470.1;ENST00000598913;MSTRG.14470.6;MSTRG.14470.5;MSTRG.14470.4;MSTRG.14470.8;MSTRG.14470.11;MSTRG.14470.7;MSTRG.14470.9;MSTRG.14470.12;MSTRG.14470.13;ENST00000314471;ENST00000614559;ENST00000601613;ENST00000599712;ENST00000611159;ENST00000594204;ENST00000596319;ENST00000595476;ENST00000598605	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:HGNC:25492]	17.42	22.19	16.75	6.67	7.77	6.63	2.29	1.2	0.01	0.2	up	yes
MSTRG.14475	ZFP36	ENST00000597629;ENST00000594045;ENST00000600033	"GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0035278(negative regulation of translation involved in gene silencing by miRNA);GO:0035556(intracellular signal transduction);GO:0043488(regulation of mRNA stability);GO:0045638(negative regulation of myeloid cell differentiation);GO:0046872(metal ion binding);GO:0050728(negative regulation of inflammatory response);GO:0050779(RNA destabilization);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)"	NA	NA	NA	ZFP36 ring finger protein [Source:HGNC Symbol;Acc:HGNC:12862]	47.45	28.12	53.2	2.78	2.55	3.98	13.05	3.71	0	0.15	up	yes
MSTRG.1449	TMEM167B	ENST00000338272;MSTRG.1449.2;ENST00000479160;ENST00000473828	GO:0000139(Golgi membrane);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 167B [Source:HGNC Symbol;Acc:HGNC:30187]	27.68	32.78	21.97	11.06	9.15	7.18	2.43	1.28	0.02	0.25	up	yes
MSTRG.14493	MAP3K10	MSTRG.14493.1;ENST00000253055;ENST00000593906;ENST00000594951;ENST00000593502;ENST00000597986;ENST00000601702;ENST00000594569;ENST00000594791	"GO:0000165(MAPK cascade);GO:0000186(activation of MAPKK activity);GO:0003714(transcription corepressor activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004706(JUN kinase kinase kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007224(smoothened signaling pathway);GO:0007254(JNK cascade);GO:0007256(activation of JNKK activity);GO:0007257(activation of JUN kinase activity);GO:0008219(cell death);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043425(bHLH transcription factor binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043507(positive regulation of JUN kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046330(positive regulation of JNK cascade);GO:0046777(protein autophosphorylation)"	NA	NA	NA	mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849]	5.85	6.23	4.82	1.82	2.12	2.63	2.19	1.13	0.01	0.22	up	yes
MSTRG.1450	SARS	MSTRG.1450.1;ENST00000234677;ENST00000482384;ENST00000477544;ENST00000369923;ENST00000471705;ENST00000468588	GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004828(serine-tRNA ligase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0006434(seryl-tRNA aminoacylation);GO:0008033(tRNA processing);GO:0010467(gene expression);GO:0070062(extracellular exosome);GO:0097056(selenocysteinyl-tRNA(Sec) biosynthetic process)	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	seryl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:10537]	94.23	107.08	112.74	31.62	36.4	37.72	2.91	1.54	0	0.16	up	yes
MSTRG.14504	PLD3	ENST00000599685;ENST00000600479;ENST00000392032;MSTRG.14504.4;MSTRG.14504.5;MSTRG.14504.6;MSTRG.14504.7;MSTRG.14504.8;ENST00000598962;ENST00000409419;ENST00000409587;ENST00000602131;ENST00000409735;ENST00000600948;ENST00000356508;ENST00000596682;ENST00000594908;ENST00000622968;ENST00000493006;ENST00000359274;ENST00000464586;ENST00000485448;ENST00000599353;ENST00000480030;ENST00000475983;ENST00000596470;ENST00000488311	GO:0003824(catalytic activity);GO:0004630(phospholipase D activity);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0006644(phospholipid metabolic process);GO:0006655(phosphatidylglycerol biosynthetic process);GO:0008152(metabolic process);GO:0016021(integral component of membrane);GO:0016042(lipid catabolic process);GO:0044281(small molecule metabolic process);GO:0046474(glycerophospholipid biosynthetic process);GO:0070062(extracellular exosome);GO:0070290(N-acylphosphatidylethanolamine-specific phospholipase D activity)	NA	NA	NA	"phospholipase D family, member 3 [Source:HGNC Symbol;Acc:HGNC:17158]"	20.09	19.39	16.7	5.55	5.59	13.12	2.82	1.5	0.05	0.34	up	yes
MSTRG.14512	BLVRB	ENST00000595483;ENST00000263368;ENST00000601346;ENST00000597870	GO:0004074(biliverdin reductase activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006778(porphyrin-containing compound metabolic process);GO:0042167(heme catabolic process);GO:0042602(riboflavin reductase (NADPH) activity);GO:0044281(small molecule metabolic process);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)	00740(Riboflavin metabolism);00860(Porphyrin and chlorophyll metabolism)	NA	NA	biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063]	28.9	40.16	29.33	10.43	11.46	14.22	2.5	1.32	0.02	0.25	up	yes
MSTRG.14515	LTBP4	ENST00000600026;ENST00000308370;ENST00000594537;ENST00000593738;ENST00000396819;ENST00000595529;MSTRG.14515.10;ENST00000243562;MSTRG.14515.11;MSTRG.14515.13;MSTRG.14515.14;ENST00000546155;ENST00000598256;ENST00000598055;ENST00000601032;ENST00000612121;ENST00000600499;ENST00000610893;ENST00000612845;ENST00000599724;ENST00000597071;ENST00000602251;ENST00000595118;ENST00000622565;ENST00000618486;ENST00000593463;ENST00000318809;ENST00000596351;ENST00000617753;ENST00000594448;ENST00000595665;ENST00000622457;ENST00000594116;ENST00000598178;ENST00000597151;ENST00000599225;ENST00000598166	GO:0001558(regulation of cell growth);GO:0005024(transforming growth factor beta-activated receptor activity);GO:0005178(integrin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005623(cell);GO:0006457(protein folding);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007275(multicellular organismal development);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0030162(regulation of proteolysis);GO:0030198(extracellular matrix organization);GO:0030252(growth hormone secretion);GO:0031012(extracellular matrix);GO:0045595(regulation of cell differentiation);GO:0046879(hormone secretion);GO:0050431(transforming growth factor beta binding);GO:0070062(extracellular exosome)	NA	NA	NA	latent transforming growth factor beta binding protein 4 [Source:HGNC Symbol;Acc:HGNC:6717]	11.01	8.48	9.15	3.42	3.62	5.58	2.46	1.3	0	0.19	up	yes
MSTRG.14519	ITPKC	ENST00000263370;ENST00000597003	"GO:0002230(positive regulation of defense response to virus by host);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008440(inositol-1,4,5-trisphosphate 3-kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0043647(inositol phosphate metabolic process);GO:0044281(small molecule metabolic process);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)"	NA	NA	NA	inositol-trisphosphate 3-kinase C [Source:HGNC Symbol;Acc:HGNC:14897]	7.46	5.22	6.11	2.82	3.37	3.16	2	1	0	0.14	up	yes
MSTRG.14521	SNRPA	ENST00000601545;ENST00000243563;ENST00000601253;ENST00000597353;ENST00000599362;ENST00000599570;ENST00000601393;ENST00000600456;ENST00000598452;ENST00000596860	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005685(U1 snRNP);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0017069(snRNA binding);GO:0044822(poly(A) RNA binding)"	03040(Spliceosome)	NA	NA	small nuclear ribonucleoprotein polypeptide A [Source:HGNC Symbol;Acc:HGNC:11151]	13.57	13.72	8.99	39.02	36.84	34.06	0.33	-1.58	0.01	0.23	down	yes
MSTRG.1454	PSRC1	MSTRG.1454.1;MSTRG.1454.2;MSTRG.1454.3;MSTRG.1454.4;MSTRG.1454.5;MSTRG.1454.6;ENST00000369904;ENST00000409267;ENST00000369907;ENST00000369909;ENST00000409138;ENST00000492431;MSTRG.1454.12;ENST00000369903;MSTRG.1454.15;ENST00000474126;ENST00000429031;ENST00000418914;ENST00000459765;ENST00000471740	"GO:0000922(spindle pole);GO:0001578(microtubule bundle formation);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0007080(mitotic metaphase plate congression);GO:0008017(microtubule binding);GO:0009987(cellular process);GO:0015630(microtubule cytoskeleton);GO:0030308(negative regulation of cell growth);GO:0030496(midbody);GO:0031116(positive regulation of microtubule polymerization);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0060236(regulation of mitotic spindle organization)"	NA	NA	NA	proline/serine-rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472]	3.71	2.02	0.67	14.41	19.01	10.57	0.21	-2.23	0.05	0.34	down	yes
MSTRG.14557	DEDD2	ENST00000336034;MSTRG.14557.1;ENST00000595337;ENST00000593804;ENST00000596251;ENST00000601135;ENST00000602075;ENST00000600559;ENST00000598090;ENST00000598727;ENST00000593561;ENST00000602201;ENST00000598200	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006396(RNA processing);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0016075(rRNA catabolic process);GO:0019725(cellular homeostasis);GO:0030159(receptor signaling complex scaffold activity);GO:0030262(apoptotic nuclear changes);GO:0035556(intracellular signal transduction);GO:0042981(regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)"	NA	NA	NA	death effector domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24450]	4.97	4.12	4.21	1.93	1.09	1.73	2.16	1.11	0.02	0.26	up	yes
MSTRG.14562	PAFAH1B3	ENST00000262890;ENST00000538771;ENST00000594989;ENST00000595530;ENST00000596265;ENST00000597333;ENST00000601865;ENST00000599778	GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0007283(spermatogenesis);GO:0007399(nervous system development);GO:0007420(brain development);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016042(lipid catabolic process);GO:0042802(identical protein binding);GO:0046982(protein heterodimerization activity);GO:0047179(platelet-activating factor acetyltransferase activity);GO:0070062(extracellular exosome)	00565(Ether lipid metabolism);01100(Metabolic pathways)	NA	NA	"platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) [Source:HGNC Symbol;Acc:HGNC:8576]"	7.14	4.44	4.1	16.16	16.21	12.08	0.42	-1.24	0.04	0.3	down	yes
MSTRG.14591	PLAUR	ENST00000339082;ENST00000593447;ENST00000601723;ENST00000340093;ENST00000221264;ENST00000595038;ENST00000594364;ENST00000593714;ENST00000599892;ENST00000597107;ENST00000602141;ENST00000593939;ENST00000593396;ENST00000598875;ENST00000599546;ENST00000601876	GO:0001934(positive regulation of protein phosphorylation);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006501(C-terminal protein lipidation);GO:0006928(movement of cell or subcellular component);GO:0006935(chemotaxis);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0016021(integral component of membrane);GO:0016255(attachment of GPI anchor to protein);GO:0019898(extrinsic component of membrane);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0030162(regulation of proteolysis);GO:0030377(urokinase plasminogen activator receptor activity);GO:0031225(anchored component of membrane);GO:0038195(urokinase plasminogen activator signaling pathway);GO:0042730(fibrinolysis);GO:0043066(negative regulation of apoptotic process);GO:0043388(positive regulation of DNA binding);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0070062(extracellular exosome);GO:0071438(invadopodium membrane);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)	04610(Complement and coagulation cascades)	NA	NA	"plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053]"	13.58	12.17	10.01	4.24	5.32	6.37	2.35	1.23	0.01	0.21	up	yes
MSTRG.14618	ZNF227	ENST00000590871;ENST00000391961;ENST00000621083;ENST00000588567;ENST00000586228;ENST00000588219;ENST00000313040;ENST00000589707;ENST00000591019;ENST00000588394;ENST00000589005;ENST00000586048;ENST00000589237	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 227 [Source:HGNC Symbol;Acc:HGNC:13020]	2.92	7.44	6.12	1.22	0.93	1.02	2.23	1.16	0.02	0.27	up	yes
MSTRG.14630	CEACAM19	ENST00000344956;ENST00000425690;MSTRG.14630.3;ENST00000403059;ENST00000187830;ENST00000406449;ENST00000587785;ENST00000622237;ENST00000618372;ENST00000358777;ENST00000480278;ENST00000459648	GO:0016021(integral component of membrane)	NA	NA	NA	carcinoembryonic antigen-related cell adhesion molecule 19 [Source:HGNC Symbol;Acc:HGNC:31951]	5.3	5.46	4.74	1.95	2.17	1.82	2.04	1.03	0	0.16	up	yes
MSTRG.14633	BCL3	MSTRG.14633.1;MSTRG.14633.2;ENST00000403534;ENST00000487394;ENST00000164227;ENST00000444487;ENST00000473468;ENST00000464319;ENST00000474300;ENST00000477832;ENST00000473473	"GO:0000060(protein import into nucleus, translocation);GO:0002268(follicular dendritic cell differentiation);GO:0002315(marginal zone B cell differentiation);GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0002467(germinal center formation);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0008134(transcription factor binding);GO:0009615(response to virus);GO:0010225(response to UV-C);GO:0019730(antimicrobial humoral response);GO:0030198(extracellular matrix organization);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0030674(protein binding, bridging);GO:0032729(positive regulation of interferon-gamma production);GO:0032996(Bcl3-Bcl10 complex);GO:0033257(Bcl3/NF-kappaB2 complex);GO:0042088(T-helper 1 type immune response);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0042742(defense response to bacterium);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0042832(defense response to protozoan);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043234(protein complex);GO:0045064(T-helper 2 cell differentiation);GO:0045082(positive regulation of interleukin-10 biosynthetic process);GO:0045171(intercellular bridge);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0045727(positive regulation of translation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048471(perinuclear region of cytoplasm);GO:0048536(spleen development);GO:0051101(regulation of DNA binding);GO:0051457(maintenance of protein location in nucleus)"	NA	NA	NA	B-cell CLL/lymphoma 3 [Source:HGNC Symbol;Acc:HGNC:998]	15.9	7.43	13.59	4.16	3.61	6.99	3.08	1.62	0.02	0.25	up	yes
MSTRG.14641	RELB	ENST00000221452;ENST00000625761;ENST00000509480;ENST00000505236;MSTRG.14641.5;ENST00000510184;ENST00000509229	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0001047(core promoter binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0010628(positive regulation of gene expression);GO:0019882(antigen processing and presentation);GO:0032688(negative regulation of interferon-beta production);GO:0032922(circadian regulation of gene expression);GO:0033256(I-kappaB/NF-kappaB complex);GO:0034097(response to cytokine);GO:0038061(NIK/NF-kappaB signaling);GO:0042088(T-helper 1 type immune response);GO:0043011(myeloid dendritic cell differentiation);GO:0045063(T-helper 1 cell differentiation);GO:0045087(innate immune response);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071470(cellular response to osmotic stress)"	04010(MAPK signaling pathway);04380(Osteoclast differentiation)	NA	NA	v-rel avian reticuloendotheliosis viral oncogene homolog B [Source:HGNC Symbol;Acc:HGNC:9956]	16.39	14.77	21.11	1.95	2.25	7.19	5.56	2.47	0.03	0.28	up	yes
MSTRG.14665	EML2	ENST00000589876;ENST00000588308;ENST00000586195;ENST00000245925;ENST00000592433;ENST00000586405;ENST00000587484;ENST00000592482;ENST00000590819;ENST00000399594;ENST00000590575;ENST00000588272;ENST00000588000;ENST00000588496;ENST00000586902;ENST00000590580;ENST00000592853;ENST00000586770;ENST00000587804;ENST00000591721;ENST00000593255;ENST00000590043;ENST00000590018;ENST00000588420	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005874(microtubule);GO:0005875(microtubule associated complex);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0008017(microtubule binding);GO:0010968(regulation of microtubule nucleation);GO:0015631(tubulin binding);GO:0031115(negative regulation of microtubule polymerization);GO:0072686(mitotic spindle)	NA	NA	NA	echinoderm microtubule associated protein like 2 [Source:HGNC Symbol;Acc:HGNC:18035]	12.25	13.02	10.12	2.04	2.04	3.92	4.01	2	0.01	0.23	up	yes
MSTRG.14686	PPP5C	ENST00000012443;MSTRG.14686.2;ENST00000478046;ENST00000391919;ENST00000467902;ENST00000527193;ENST00000487483;ENST00000532058;ENST00000486994;ENST00000467502;ENST00000493347;ENST00000595055;ENST00000491003;ENST00000492109;ENST00000525507;ENST00000527623	"GO:0001933(negative regulation of protein phosphorylation);GO:0001965(G-protein alpha-subunit binding);GO:0003723(RNA binding);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006351(transcription, DNA-templated);GO:0006470(protein dephosphorylation);GO:0007067(mitotic nuclear division);GO:0007165(signal transduction);GO:0008017(microtubule binding);GO:0008289(lipid binding);GO:0010288(response to lead ion);GO:0016020(membrane);GO:0016576(histone dephosphorylation);GO:0016787(hydrolase activity);GO:0031072(heat shock protein binding);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043204(perikaryon);GO:0043231(intracellular membrane-bounded organelle);GO:0043278(response to morphine);GO:0046872(metal ion binding);GO:0051259(protein oligomerization);GO:0051291(protein heterooligomerization);GO:0060548(negative regulation of cell death);GO:0070301(cellular response to hydrogen peroxide);GO:0071276(cellular response to cadmium ion);GO:0071944(cell periphery);GO:1901215(negative regulation of neuron death);GO:1990635(proximal dendrite);GO:2000324(positive regulation of glucocorticoid receptor signaling pathway)"	04010(MAPK signaling pathway)	NA	NA	"protein phosphatase 5, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9322]"	6.78	5.68	6.42	16.11	18.52	14.44	0.44	-1.2	0.01	0.19	down	yes
MSTRG.14694	CALM3	ENST00000391918;ENST00000291295;ENST00000597743;ENST00000477244;ENST00000598871;ENST00000602169;ENST00000594523;ENST00000597868;ENST00000599839;ENST00000596362;ENST00000482455;ENST00000486500;ENST00000595072	"GO:0000922(spindle pole);GO:0002027(regulation of heart rate);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002576(platelet degranulation);GO:0005509(calcium ion binding);GO:0005513(detection of calcium ion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0005980(glycogen catabolic process);GO:0006006(glucose metabolic process);GO:0006936(muscle contraction);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0007264(small GTPase mediated signal transduction);GO:0007268(synaptic transmission);GO:0007596(blood coagulation);GO:0007603(phototransduction, visible light);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0016056(rhodopsin mediated signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0021762(substantia nigra development);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0030017(sarcomere);GO:0030168(platelet activation);GO:0030801(positive regulation of cyclic nucleotide metabolic process);GO:0031432(titin binding);GO:0031954(positive regulation of protein autophosphorylation);GO:0031982(vesicle);GO:0031996(thioesterase binding);GO:0031997(N-terminal myristoylation domain binding);GO:0032465(regulation of cytokinesis);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0034704(calcium channel complex);GO:0035307(positive regulation of protein dephosphorylation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043274(phospholipase binding);GO:0043539(protein serine/threonine kinase activator activity);GO:0043647(inositol phosphate metabolic process);GO:0044281(small molecule metabolic process);GO:0044325(ion channel binding);GO:0045087(innate immune response);GO:0046209(nitric oxide metabolic process);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050999(regulation of nitric-oxide synthase activity);GO:0051343(positive regulation of cyclic-nucleotide phosphodiesterase activity);GO:0051592(response to calcium ion);GO:0055117(regulation of cardiac muscle contraction);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity);GO:0060316(positive regulation of ryanodine-sensitive calcium-release channel activity);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0072542(protein phosphatase activator activity);GO:1901844(regulation of cell communication by electrical coupling involved in cardiac conduction)"	04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04114(Oocyte meiosis);04270(Vascular smooth muscle contraction);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04740(Olfactory transduction);04744(Phototransduction);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04916(Melanogenesis);04970(Salivary secretion);04971(Gastric acid secretion);05010(Alzheimer's disease);05152(Tuberculosis);05214(Glioma)	NA	NA	"calmodulin 3 (phosphorylase kinase, delta) [Source:HGNC Symbol;Acc:HGNC:1449]"	20.73	16.98	13.6	55.8	60.56	52.09	0.33	-1.58	0.01	0.2	down	yes
MSTRG.147	ICMT	MSTRG.147.3;ENST00000343813;MSTRG.147.4;MSTRG.147.1;MSTRG.147.2;MSTRG.147.6;MSTRG.147.7;ENST00000495791;ENST00000489498;ENST00000474756	GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0003880(protein C-terminal carboxyl O-methyltransferase activity);GO:0004671(protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006464(cellular protein modification process);GO:0006479(protein methylation);GO:0006481(C-terminal protein methylation);GO:0006612(protein targeting to membrane);GO:0008104(protein localization);GO:0008140(cAMP response element binding protein binding);GO:0008284(positive regulation of cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0035264(multicellular organism growth);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046499(S-adenosylmethioninamine metabolic process);GO:0046578(regulation of Ras protein signal transduction)	NA	NA	NA	isoprenylcysteine carboxyl methyltransferase [Source:HGNC Symbol;Acc:HGNC:5350]	11.03	14.45	14.18	31.62	21.83	23.83	0.45	-1.15	0	0.18	down	yes
MSTRG.14713	ZC3H4	MSTRG.14713.2;MSTRG.14713.1;ENST00000253048;MSTRG.14713.4;ENST00000594019;MSTRG.14713.7;ENST00000597069	GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding)	NA	NA	NA	zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:HGNC:17808]	0.52	0.64	1.91	6.68	7.49	5.74	0.23	-2.1	0.02	0.26	down	yes
MSTRG.14715	BBC3	ENST00000601438;MSTRG.14715.1;ENST00000300880;ENST00000341983;ENST00000449228;MSTRG.14715.3;ENST00000439096;MSTRG.14715.8;ENST00000598636	GO:0001836(release of cytochrome c from mitochondria);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0008340(determination of adult lifespan);GO:0012501(programmed cell death);GO:0032464(positive regulation of protein homooligomerization);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0034976(response to endoplasmic reticulum stress);GO:0043525(positive regulation of neuron apoptotic process);GO:0045926(negative regulation of growth);GO:0051209(release of sequestered calcium ion into cytosol);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070245(positive regulation of thymocyte apoptotic process);GO:0071456(cellular response to hypoxia);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097190(apoptotic signaling pathway);GO:0097193(intrinsic apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2001056(positive regulation of cysteine-type endopeptidase activity);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)	04115(p53 signaling pathway);05016(Huntington's disease);05162(Measles)	NA	NA	BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868]	4.16	4.97	6.86	0.05	0.54	0.52	4.81	2.27	0.01	0.21	up	yes
MSTRG.14719	INAFM1	ENST00000601154;ENST00000221922;MSTRG.14719.2;MSTRG.14719.4;MSTRG.14719.5;MSTRG.14719.6;MSTRG.14719.8;MSTRG.14719.7;ENST00000599398;ENST00000595659;ENST00000596938;ENST00000600117;ENST00000552360	GO:0016021(integral component of membrane)	NA	NA	NA	InaF-motif containing 1 [Source:HGNC Symbol;Acc:HGNC:27406]	11.26	10.84	10.74	3.44	3.74	4.19	2.63	1.4	0	0.1	up	yes
MSTRG.14723	KPTN	ENST00000338134;ENST00000600551;MSTRG.14723.3;ENST00000594208;ENST00000595554;ENST00000594139;ENST00000595484;ENST00000598699	GO:0003779(actin binding);GO:0005634(nucleus);GO:0005815(microtubule organizing center);GO:0006928(movement of cell or subcellular component);GO:0007015(actin filament organization);GO:0007605(sensory perception of sound);GO:0015629(actin cytoskeleton);GO:0030426(growth cone);GO:0032420(stereocilium);GO:0048471(perinuclear region of cytoplasm)	NA	NA	NA	kaptin (actin binding protein) [Source:HGNC Symbol;Acc:HGNC:6404]	1.81	2.17	1.98	5.59	5.8	4.61	0.44	-1.19	0	0.14	down	yes
MSTRG.14737	LIG1	MSTRG.14737.1;ENST00000263274;ENST00000597146;ENST00000536218;ENST00000599322;ENST00000594759;ENST00000427526;ENST00000594067;ENST00000613670;ENST00000601091;ENST00000596672;ENST00000596332;ENST00000596457;ENST00000597901;ENST00000542460;ENST00000595758;ENST00000596104;ENST00000599165;ENST00000593425;ENST00000600055;ENST00000598938	"GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0000724(double-strand break repair via homologous recombination);GO:0003677(DNA binding);GO:0003909(DNA ligase activity);GO:0003910(DNA ligase (ATP) activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005794(Golgi apparatus);GO:0006259(DNA metabolic process);GO:0006260(DNA replication);GO:0006266(DNA ligation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006273(lagging strand elongation);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006310(DNA recombination);GO:0009653(anatomical structure morphogenesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0042542(response to hydrogen peroxide);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0051103(DNA ligation involved in DNA repair);GO:0051301(cell division);GO:0071897(DNA biosynthetic process);GO:1903461(Okazaki fragment processing involved in mitotic DNA replication);GO:1903469(removal of RNA primer involved in mitotic DNA replication)"	03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair)	NA	NA	"ligase I, DNA, ATP-dependent [Source:HGNC Symbol;Acc:HGNC:6598]"	1.24	0.93	1.34	8.92	8	6.26	0.24	-2.04	0	0.17	down	yes
MSTRG.14766	PPP1R15A	ENST00000200453;ENST00000600406	GO:0000164(protein phosphatase type 1 complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008157(protein phosphatase 1 binding);GO:0008599(protein phosphatase type 1 regulator activity);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0019888(protein phosphatase regulator activity);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032058(positive regulation of translational initiation in response to stress);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034976(response to endoplasmic reticulum stress);GO:0035308(negative regulation of protein dephosphorylation);GO:0036496(regulation of translational initiation by eIF2 alpha dephosphorylation);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0060734(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070262(peptidyl-serine dephosphorylation);GO:0070972(protein localization to endoplasmic reticulum);GO:0071862(protein phosphatase type 1 activator activity);GO:1902310(positive regulation of peptidyl-serine dephosphorylation);GO:1903573(negative regulation of response to endoplasmic reticulum stress);GO:1903898(negative regulation of PERK-mediated unfolded protein response);GO:1903912(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:1903917(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)	04141(Protein processing in endoplasmic reticulum)	NA	NA	"protein phosphatase 1, regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375]"	475.04	359	347.93	26.81	31.44	16.08	15.65	3.97	0	0.17	up	yes
MSTRG.14768	PPP1R15A	MSTRG.14768.1;MSTRG.14768.2;MSTRG.14768.3	NA	NA	NA	NA	NA	4.39	2.4	1.4	0	0	0	4.22	2.08	0.02	0.25	up	yes
MSTRG.14776	GYS1	ENST00000323798;ENST00000263276;ENST00000594220;ENST00000472004;ENST00000496048;ENST00000484289;ENST00000457974	"GO:0004373(glycogen (starch) synthase activity);GO:0005515(protein binding);GO:0005536(glucose binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0006006(glucose metabolic process);GO:0007507(heart development);GO:0016020(membrane);GO:0016234(inclusion body);GO:0019901(protein kinase binding);GO:0044281(small molecule metabolic process);GO:0061547(glycogen synthase activity, transferring glucose-1-phosphate)"	00500(Starch and sucrose metabolism);04910(Insulin signaling pathway)	NA	NA	glycogen synthase 1 (muscle) [Source:HGNC Symbol;Acc:HGNC:4706]	3	3.04	4.69	10.49	9.89	12.28	0.39	-1.37	0.01	0.24	down	yes
MSTRG.14781	LIN7B	ENST00000391864;MSTRG.14781.2;ENST00000221459;ENST00000595200;ENST00000486217;ENST00000469137;ENST00000474252;ENST00000465141	GO:0005515(protein binding);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0006887(exocytosis);GO:0007264(small GTPase mediated signal transduction);GO:0007268(synaptic transmission);GO:0007269(neurotransmitter secretion);GO:0008105(asymmetric protein localization);GO:0014069(postsynaptic density);GO:0015031(protein transport);GO:0016323(basolateral plasma membrane);GO:0019904(protein domain specific binding);GO:0030165(PDZ domain binding);GO:0043005(neuron projection);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0097016(L27 domain binding);GO:0097025(MPP7-DLG1-LIN7 complex);GO:1903361(protein localization to basolateral plasma membrane)	NA	NA	NA	lin-7 homolog B (C. elegans) [Source:HGNC Symbol;Acc:HGNC:17788]	2.68	2.24	1.82	0.36	0.33	0.63	2.47	1.31	0	0.18	up	yes
MSTRG.14784	TRPM4	ENST00000252826;ENST00000599628;ENST00000595519;ENST00000427978;ENST00000596338;ENST00000598502;ENST00000594568;ENST00000595071;ENST00000597316	GO:0002407(dendritic cell chemotaxis);GO:0002724(regulation of T cell cytokine production);GO:0005216(ion channel activity);GO:0005227(calcium activated cation channel activity);GO:0005262(calcium channel activity);GO:0005516(calmodulin binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0008284(positive regulation of cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016925(protein sumoylation);GO:0034220(ion transmembrane transport);GO:0042310(vasoconstriction);GO:0042391(regulation of membrane potential);GO:0055085(transmembrane transport);GO:0061337(cardiac conduction);GO:0070588(calcium ion transmembrane transport);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0098655(cation transmembrane transport)	NA	NA	NA	"transient receptor potential cation channel, subfamily M, member 4 [Source:HGNC Symbol;Acc:HGNC:17993]"	5.51	4.9	2.96	0.49	0.29	0.74	3.89	1.96	0.01	0.23	up	yes
MSTRG.14795	RCN3	ENST00000270645;MSTRG.14795.2;ENST00000597801;ENST00000593644;ENST00000598833;ENST00000593483	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen)	NA	NA	NA	"reticulocalbin 3, EF-hand calcium binding domain [Source:HGNC Symbol;Acc:HGNC:21145]"	20.14	20.25	18.57	7.05	8.25	13.1	2.33	1.22	0.03	0.28	up	yes
MSTRG.1480	SLC16A4	ENST00000369779;ENST00000437429;ENST00000541986;ENST00000472422;ENST00000369781;ENST00000461647;ENST00000528649;ENST00000492412;ENST00000467986;ENST00000497687	GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 16, member 4 [Source:HGNC Symbol;Acc:HGNC:10925]"	6.98	7.04	6.19	0.85	0.78	2.93	3.93	1.97	0.03	0.28	up	yes
MSTRG.1482	DRAM2	MSTRG.1482.2;MSTRG.1482.1;MSTRG.1482.3;MSTRG.1482.4;MSTRG.1482.5;ENST00000286692;ENST00000484310;ENST00000539140;ENST00000461449;ENST00000496430;ENST00000477588;MSTRG.1482.12;ENST00000480600;ENST00000462092;ENST00000490780;ENST00000463682	GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0005794(Golgi apparatus);GO:0006915(apoptotic process);GO:0010506(regulation of autophagy);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle)	NA	NA	NA	DNA-damage regulated autophagy modulator 2 [Source:HGNC Symbol;Acc:HGNC:28769]	17.67	18.14	14.01	6.67	4.17	7.49	2.53	1.34	0.03	0.3	up	yes
MSTRG.14820	TBC1D17	ENST00000221543;ENST00000622860;MSTRG.14820.3;MSTRG.14820.4;ENST00000535102;ENST00000594996;ENST00000598789;ENST00000599049;ENST00000596243;ENST00000594984;ENST00000600354	"GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005776(autophagosome);GO:0005829(cytosol);GO:0006914(autophagy);GO:0015031(protein transport);GO:0031410(cytoplasmic vesicle);GO:0042147(retrograde transport, endosome to Golgi);GO:0043547(positive regulation of GTPase activity)"	NA	NA	NA	"TBC1 domain family, member 17 [Source:HGNC Symbol;Acc:HGNC:25699]"	7.75	6.21	7.9	2.82	2.75	3.81	2.26	1.17	0	0.18	up	yes
MSTRG.14825	ZNF473	ENST00000391821;ENST00000270617;ENST00000445728;ENST00000601364;ENST00000594968;ENST00000599155;ENST00000598802	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006398(histone mRNA 3'-end processing);GO:0008334(histone mRNA metabolic process);GO:0010467(gene expression);GO:0015030(Cajal body);GO:0031124(mRNA 3'-end processing);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 473 [Source:HGNC Symbol;Acc:HGNC:23239]	0.32	3.64	0.67	3.85	3.64	2.53	0.31	-1.7	0.04	0.31	down	yes
MSTRG.14837	SPIB	ENST00000600859;MSTRG.14837.2;ENST00000613923;ENST00000440232;ENST00000601098;ENST00000599857;ENST00000600746;ENST00000593887;ENST00000595904;ENST00000596425;ENST00000593407;ENST00000593981;ENST00000596648;ENST00000597963;ENST00000596221;ENST00000595883	"GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding)"	NA	NA	NA	Spi-B transcription factor (Spi-1/PU.1 related) [Source:HGNC Symbol;Acc:HGNC:11242]	1.47	1.77	1.92	4.84	5.37	5.01	0.43	-1.23	0	0.15	down	yes
MSTRG.14927	ZNF818P	MSTRG.14927.1	NA	NA	NA	NA	NA	0.1	0.37	0.25	1.61	1.53	1.09	0.45	-1.14	0	0.12	down	yes
MSTRG.14943	OSCAR	MSTRG.14943.1;ENST00000391761;MSTRG.14943.2;ENST00000356532;ENST00000616447;ENST00000359649;ENST00000358375;ENST00000351806;ENST00000611261;ENST00000616215	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	04380(Osteoclast differentiation)	NA	NA	"osteoclast associated, immunoglobulin-like receptor [Source:HGNC Symbol;Acc:HGNC:29960]"	6.85	5.23	10.55	0.06	0.01	0.02	8.45	3.08	0	0.17	up	yes
MSTRG.14975	PTPRH	MSTRG.14975.2;MSTRG.14975.3;MSTRG.14975.1;MSTRG.14975.4;MSTRG.14975.6;MSTRG.14975.5;ENST00000263434;ENST00000588559;ENST00000586852;ENST00000586310;ENST00000588370;ENST00000587662	GO:0004725(protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0006470(protein dephosphorylation);GO:0006915(apoptotic process);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation)	NA	NA	NA	"protein tyrosine phosphatase, receptor type, H [Source:HGNC Symbol;Acc:HGNC:9672]"	10.01	11.19	17.71	1.12	1.04	2.85	5.79	2.53	0.02	0.25	up	yes
MSTRG.14990	UBE2S	ENST00000264552;ENST00000587845;ENST00000589978;ENST00000592570	GO:0004842(ubiquitin-protein transferase activity);GO:0005524(ATP binding);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0006464(cellular protein modification process);GO:0010458(exit from mitosis);GO:0010994(free ubiquitin chain polymerization);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0035519(protein K29-linked ubiquitination);GO:0044314(protein K27-linked ubiquitination);GO:0051301(cell division);GO:0051488(activation of anaphase-promoting complex activity);GO:0061630(ubiquitin protein ligase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070534(protein K63-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0085020(protein K6-linked ubiquitination)	04120(Ubiquitin mediated proteolysis)	NA	NA	ubiquitin-conjugating enzyme E2S [Source:HGNC Symbol;Acc:HGNC:17895]	24.67	17.59	18.46	75.37	108.46	47.45	0.29	-1.78	0.04	0.33	down	yes
MSTRG.14994	ZNF579	ENST00000325421;MSTRG.14994.2;ENST00000592239	"GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 579 [Source:HGNC Symbol;Acc:HGNC:26646]	7.34	6.29	6.29	2.26	2.53	2.78	2.37	1.24	0	0.08	up	yes
MSTRG.15001	U2AF2	ENST00000450554;ENST00000308924;ENST00000588850;ENST00000587196;ENST00000592867;ENST00000592874;ENST00000590551;ENST00000587275	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0000974(Prp19 complex);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006397(mRNA processing);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0016607(nuclear speck);GO:0019899(enzyme binding);GO:0031124(mRNA 3'-end processing);GO:0033120(positive regulation of RNA splicing);GO:0044822(poly(A) RNA binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0070742(C2H2 zinc finger domain binding);GO:1903146(regulation of mitochondrion degradation);GO:1903955(positive regulation of protein targeting to mitochondrion)"	03040(Spliceosome)	NA	NA	U2 small nuclear RNA auxiliary factor 2 [Source:HGNC Symbol;Acc:HGNC:23156]	25.43	22.45	23.87	53.75	62.11	36.27	0.47	-1.08	0.05	0.33	down	yes
MSTRG.15060	ZNF304	ENST00000443917;ENST00000598744;ENST00000282286	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 304 [Source:HGNC Symbol;Acc:HGNC:13505]	2.45	3.12	3	0.45	0.37	1.19	2.44	1.28	0.03	0.29	up	yes
MSTRG.15071	ZNF550	ENST00000601415;MSTRG.15071.2;MSTRG.15071.3;ENST00000457177;ENST00000376230;ENST00000447310;MSTRG.15071.7;ENST00000506609;ENST00000595560	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 550 [Source:HGNC Symbol;Acc:HGNC:28643]	6.88	10.09	7.56	1.87	1.77	1.58	2.88	1.53	0	0.13	up	yes
MSTRG.151	NOL9	ENST00000377705;MSTRG.151.2;ENST00000464383;ENST00000462798;ENST00000460777	"GO:0000448(cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000460(maturation of 5.8S rRNA);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006396(RNA processing);GO:0016020(membrane);GO:0016310(phosphorylation);GO:0051731(polynucleotide 5'-hydroxyl-kinase activity)"	NA	NA	NA	nucleolar protein 9 [Source:HGNC Symbol;Acc:HGNC:26265]	1.18	2.09	2.4	4.34	3.87	3.43	0.49	-1.03	0.01	0.23	down	yes
MSTRG.15166	.	MSTRG.15166.1	NA	NA	NA	NA	NA	2.22	0.44	1.45	0.12	0.34	0.86	2.38	1.25	0.01	0.2	up	yes
MSTRG.15169	ITGB1BP1	ENST00000360635;ENST00000238091;ENST00000355346;ENST00000483795;MSTRG.15169.6;MSTRG.15169.5;ENST00000490426;ENST00000497031;ENST00000464228;ENST00000460720;ENST00000465527;ENST00000359712;ENST00000488451;ENST00000470507;ENST00000456913;ENST00000482798;ENST00000492079;ENST00000463190;ENST00000494563;ENST00000467606;ENST00000484735;ENST00000460001;ENST00000497105	"GO:0001726(ruffle);GO:0002043(blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:0005092(GDP-dissociation inhibitor activity);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006469(negative regulation of protein kinase activity);GO:0006933(negative regulation of cell adhesion involved in substrate-bound cell migration);GO:0007160(cell-matrix adhesion);GO:0007219(Notch signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0008565(protein transporter activity);GO:0010595(positive regulation of endothelial cell migration);GO:0010764(negative regulation of fibroblast migration);GO:0015031(protein transport);GO:0016020(membrane);GO:0016477(cell migration);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0030027(lamellipodium);GO:0030154(cell differentiation);GO:0031214(biomineral tissue development);GO:0032091(negative regulation of protein binding);GO:0032148(activation of protein kinase B activity);GO:0032403(protein complex binding);GO:0033622(integrin activation);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0035148(tube formation);GO:0035556(intracellular signal transduction);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0043087(regulation of GTPase activity);GO:0043113(receptor clustering);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045747(positive regulation of Notch signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048471(perinuclear region of cytoplasm);GO:0050880(regulation of blood vessel size);GO:0051451(myoblast migration);GO:0051496(positive regulation of stress fiber assembly);GO:0051781(positive regulation of cell division);GO:0051894(positive regulation of focal adhesion assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0070062(extracellular exosome);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071944(cell periphery);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0090314(positive regulation of protein targeting to membrane);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:2001044(regulation of integrin-mediated signaling pathway)"	NA	NA	NA	integrin beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927]	5.87	6.04	4.87	12.87	13.7	8.3	0.48	-1.05	0.04	0.31	down	yes
MSTRG.15170	CPSF3	ENST00000238112;ENST00000475482;ENST00000460593;ENST00000489629;ENST00000489403	"GO:0000398(mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0004521(endoribonuclease activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006378(mRNA polyadenylation);GO:0006379(mRNA cleavage);GO:0006398(histone mRNA 3'-end processing);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0008409(5'-3' exonuclease activity);GO:0010467(gene expression);GO:0030529(ribonucleoprotein complex);GO:0031124(mRNA 3'-end processing);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)"	03015(mRNA surveillance pathway)	NA	NA	"cleavage and polyadenylation specific factor 3, 73kDa [Source:HGNC Symbol;Acc:HGNC:2326]"	8.79	10.71	13.38	31.51	23.48	18.92	0.38	-1.38	0.01	0.23	down	yes
MSTRG.15181	KLF11	ENST00000401510;ENST00000305883;ENST00000440320;ENST00000535335	"GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0008285(negative regulation of cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	Kruppel-like factor 11 [Source:HGNC Symbol;Acc:HGNC:11811]	26.45	21.4	19.09	6.89	6.25	4.87	3.34	1.74	0.01	0.2	up	yes
MSTRG.15183	RRM2	MSTRG.15183.1;MSTRG.15183.2;ENST00000607140;MSTRG.15183.4;ENST00000360566;ENST00000615152;ENST00000459969;ENST00000304567;ENST00000498343;ENST00000461327;ENST00000491447;ENST00000474701;ENST00000487591;ENST00000462343;ENST00000485717	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0004748(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0009186(deoxyribonucleoside diphosphate metabolic process);GO:0009262(deoxyribonucleotide metabolic process);GO:0009263(deoxyribonucleotide biosynthetic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016491(oxidoreductase activity);GO:0044281(small molecule metabolic process);GO:0046872(metal ion binding);GO:0051259(protein oligomerization);GO:0051290(protein heterotetramerization);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0055114(oxidation-reduction process)"	00230(Purine metabolism);00240(Pyrimidine metabolism);00480(Glutathione metabolism);01100(Metabolic pathways);04115(p53 signaling pathway)	NA	NA	ribonucleotide reductase M2 [Source:HGNC Symbol;Acc:HGNC:10452]	2.9	2.01	0.75	59.74	62.3	16.75	0.06	-4.15	0.02	0.27	down	yes
MSTRG.15195	PQLC3	ENST00000441908;ENST00000295083;ENST00000445921;ENST00000464700;ENST00000402361;ENST00000428481;ENST00000496444	GO:0005783(endoplasmic reticulum);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0016021(integral component of membrane)	NA	NA	NA	PQ loop repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:28503]	6.34	5.77	4.44	1.66	1.22	2.7	2.59	1.37	0.03	0.28	up	yes
MSTRG.15217	TRIB2	ENST00000155926;ENST00000483034;ENST00000381465;ENST00000405331	"GO:0004672(protein kinase activity);GO:0004860(protein kinase inhibitor activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:0008134(transcription factor binding);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0031625(ubiquitin protein ligase binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0045081(negative regulation of interleukin-10 biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0055106(ubiquitin-protein transferase regulator activity)"	NA	NA	NA	tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809]	8.38	9.42	7.73	65.14	57.32	46.04	0.15	-2.75	0	0.11	down	yes
MSTRG.15219	NBAS	ENST00000281513;ENST00000417461;ENST00000433283;MSTRG.15219.3;ENST00000485694;MSTRG.15219.7;MSTRG.15219.8;ENST00000423602	"GO:0000149(SNARE binding);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005488(binding);GO:0005622(intracellular);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016020(membrane);GO:0031965(nuclear membrane);GO:0070939(Dsl1p complex);GO:2000623(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)"	NA	NA	NA	neuroblastoma amplified sequence [Source:HGNC Symbol;Acc:HGNC:15625]	13.92	16.22	21.32	7.64	6.6	6.99	2.04	1.03	0.02	0.26	up	yes
MSTRG.15258	C2orf44	ENST00000295148;ENST00000406895	GO:0005515(protein binding);GO:0019900(kinase binding);GO:0051259(protein oligomerization)	NA	NA	NA	chromosome 2 open reading frame 44 [Source:HGNC Symbol;Acc:HGNC:26157]	1.41	3.27	2.99	6.26	6.42	4.45	0.4	-1.34	0.01	0.21	down	yes
MSTRG.15276	CENPO	ENST00000473476;MSTRG.15276.3;MSTRG.15276.4;MSTRG.15276.2;ENST00000380834;ENST00000473706;ENST00000491031;ENST00000486527;ENST00000260662;ENST00000498362;ENST00000464156;ENST00000395845	GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0007264(small GTPase mediated signal transduction);GO:0034080(CENP-A containing nucleosome assembly);GO:0034508(centromere complex assembly)	NA	NA	NA	centromere protein O [Source:HGNC Symbol;Acc:HGNC:28152]	0.86	1.26	2.65	12.99	15.09	8.43	0.16	-2.62	0.01	0.23	down	yes
MSTRG.15284	EFR3B	ENST00000401432;ENST00000403714;ENST00000402191;ENST00000405108	GO:0005488(binding)	NA	NA	NA	EFR3 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:29155]	0.4	0.15	0.2	2.71	1.7	2.67	0.39	-1.34	0.01	0.23	down	yes
MSTRG.1531	DCLRE1B	ENST00000369563;ENST00000466480	"GO:0000075(cell cycle checkpoint);GO:0000723(telomere maintenance);GO:0000781(chromosome, telomeric region);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006281(DNA repair);GO:0008409(5'-3' exonuclease activity);GO:0031627(telomeric loop formation);GO:0031848(protection from non-homologous end joining at telomere);GO:0031860(telomeric 3' overhang formation);GO:0090305(nucleic acid phosphodiester bond hydrolysis)"	NA	NA	NA	DNA cross-link repair 1B [Source:HGNC Symbol;Acc:HGNC:17641]	2.2	2.11	2.03	7.31	8.5	4.28	0.38	-1.39	0.03	0.29	down	yes
MSTRG.1534	OLFML3	ENST00000393300;ENST00000369551;ENST00000320334;ENST00000491700	GO:0005515(protein binding);GO:0007275(multicellular organismal development);GO:1903561(extracellular vesicle)	NA	NA	NA	olfactomedin-like 3 [Source:HGNC Symbol;Acc:HGNC:24956]	0.4	0.17	0.25	6.1	5.38	7.08	0.18	-2.49	0	0.1	down	yes
MSTRG.15362	TRMT61B	ENST00000419999;MSTRG.15362.1;ENST00000306108;ENST00000439947;ENST00000490390;ENST00000484060	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0016429(tRNA (adenine-N1-)-methyltransferase activity);GO:0030488(tRNA methylation);GO:0031515(tRNA (m1A) methyltransferase complex);GO:0051260(protein homooligomerization);GO:0070901(mitochondrial tRNA methylation)	NA	NA	NA	tRNA methyltransferase 61B [Source:HGNC Symbol;Acc:HGNC:26070]	1.88	3.05	4.57	7.68	7.37	6.48	0.42	-1.27	0.03	0.29	down	yes
MSTRG.15368	CLIP4	ENST00000401605;ENST00000401617;ENST00000415891;ENST00000404424;MSTRG.15368.5;MSTRG.15368.6;MSTRG.15368.7;ENST00000456385;MSTRG.15368.9;ENST00000320081;MSTRG.15368.11;MSTRG.15368.12;MSTRG.15368.13;MSTRG.15368.14;ENST00000491701;ENST00000471165;MSTRG.15368.17;ENST00000438819;ENST00000493551	GO:0005515(protein binding)	NA	NA	NA	"CAP-GLY domain containing linker protein family, member 4 [Source:HGNC Symbol;Acc:HGNC:26108]"	11.33	12.24	12.54	5.02	3.67	3.4	2.34	1.22	0	0.17	up	yes
MSTRG.15369	YPEL5	ENST00000379519;ENST00000379520;ENST00000261353;ENST00000490211;ENST00000402003;ENST00000402708;ENST00000482474;ENST00000470120;ENST00000495673	NA	NA	NA	NA	yippee-like 5 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:18329]	44.67	40.28	27.43	7.71	6.26	11.88	4.61	2.2	0.01	0.24	up	yes
MSTRG.15370	LBH	ENST00000395323;ENST00000412933;ENST00000464412;ENST00000406087;ENST00000404397;ENST00000401506;ENST00000467242;ENST00000407930;ENST00000484150	"GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organismal development);GO:0010468(regulation of gene expression);GO:0030193(regulation of blood coagulation);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	limb bud and heart development [Source:HGNC Symbol;Acc:HGNC:29532]	14.02	13.44	6.78	3.15	2.32	3.35	3.16	1.66	0.04	0.32	up	yes
MSTRG.15404	VIT	MSTRG.15404.1	NA	NA	NA	NA	NA	0.03	0.02	0	1	0.97	1.63	0.5	-1	0.01	0.23	down	yes
MSTRG.15435	AC009229.5	MSTRG.15435.1;ENST00000450854	NA	NA	NA	NA	NA	2.45	2.55	1.38	0.56	0.06	0.29	2.25	1.17	0.04	0.33	up	yes
MSTRG.15468	AC016735.2	MSTRG.15468.1;ENST00000422351;ENST00000449766;ENST00000425212	NA	NA	NA	NA	NA	0.26	0.16	0.18	2.91	2.86	1.26	0.33	-1.6	0.02	0.27	down	yes
MSTRG.1548	.	MSTRG.1548.1;MSTRG.1548.3;MSTRG.1548.2;MSTRG.1548.4	NA	NA	NA	NA	NA	3.97	6.85	9.63	0.68	0.79	0.07	3.83	1.94	0.02	0.26	up	yes
MSTRG.15480	PLEKHH2	ENST00000282406;ENST00000405223;MSTRG.15480.2;ENST00000405000;ENST00000491692;ENST00000460356;ENST00000480103;ENST00000493408	GO:0003779(actin binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0030027(lamellipodium);GO:0030835(negative regulation of actin filament depolymerization);GO:0030864(cortical actin cytoskeleton);GO:0042802(identical protein binding)	NA	NA	NA	"pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 [Source:HGNC Symbol;Acc:HGNC:30506]"	3.56	4.21	2.39	1.01	0.72	0.53	2.24	1.16	0.02	0.28	up	yes
MSTRG.1550	SLC22A15	MSTRG.1550.1;MSTRG.1550.2;MSTRG.1550.4;MSTRG.1550.5;MSTRG.1550.3;ENST00000369503;MSTRG.1550.7;ENST00000369502;ENST00000481127	GO:0006811(ion transport);GO:0016021(integral component of membrane);GO:0022857(transmembrane transporter activity);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 22, member 15 [Source:HGNC Symbol;Acc:HGNC:20301]"	6.83	8.73	11.19	0.58	0.51	0.42	5.8	2.54	0	0.14	up	yes
MSTRG.15573	CFAP36	ENST00000339012;ENST00000406691;ENST00000349456;ENST00000407816;ENST00000403007;ENST00000490934;ENST00000481791	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042995(cell projection)	NA	NA	NA	cilia and flagella associated protein 36 [Source:HGNC Symbol;Acc:HGNC:30540]	14.82	16.5	14.92	5.97	5.27	3.99	2.42	1.28	0	0.17	up	yes
MSTRG.1558	IGSF3	ENST00000369483;ENST00000369486;ENST00000318837;ENST00000481589	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0009986(cell surface);GO:0016021(integral component of membrane);GO:0032808(lacrimal gland development)	NA	NA	NA	"immunoglobulin superfamily, member 3 [Source:HGNC Symbol;Acc:HGNC:5950]"	3.98	6.35	4.16	14.61	17.77	17.09	0.3	-1.72	0.01	0.2	down	yes
MSTRG.15585	FANCL	ENST00000403295;MSTRG.15585.1;ENST00000233741;ENST00000402135;MSTRG.15585.5;ENST00000403676;ENST00000449070;ENST00000446381;ENST00000470506;ENST00000427708;ENST00000417361;ENST00000481670	GO:0002230(positive regulation of defense response to virus by host);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0007276(gamete generation);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0031625(ubiquitin protein ligase binding);GO:0042127(regulation of cell proliferation);GO:0043240(Fanconi anaemia nuclear complex);GO:0061630(ubiquitin protein ligase activity)	04120(Ubiquitin mediated proteolysis)	NA	NA	"Fanconi anemia, complementation group L [Source:HGNC Symbol;Acc:HGNC:20748]"	3.09	2.74	3.12	11.93	9.06	7.67	0.35	-1.5	0.01	0.2	down	yes
MSTRG.15644	PELI1	ENST00000358912;ENST00000466177;ENST00000494203;ENST00000468869	GO:0000209(protein polyubiquitination);GO:0001819(positive regulation of cytokine production);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008063(Toll signaling pathway);GO:0016874(ligase activity);GO:0030890(positive regulation of B cell proliferation);GO:0031398(positive regulation of protein ubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032496(response to lipopolysaccharide);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0042130(negative regulation of T cell proliferation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043331(response to dsRNA);GO:0045087(innate immune response);GO:0050868(negative regulation of T cell activation);GO:0050871(positive regulation of B cell activation);GO:0061630(ubiquitin protein ligase activity);GO:0070936(protein K48-linked ubiquitination)	NA	NA	NA	pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827]	15.71	14.01	10.32	6.54	4.35	4.35	2.25	1.17	0.04	0.32	up	yes
MSTRG.15656	SERTAD2	ENST00000313349;ENST00000476805	"GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0030308(negative regulation of cell growth);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	SERTA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30784]	16.17	18.28	25.96	9.25	6.17	5.22	2.23	1.16	0.04	0.31	up	yes
MSTRG.15668	SPRED2	MSTRG.15668.1;ENST00000356388;ENST00000443619;ENST00000452315;ENST00000421087;MSTRG.15668.6;ENST00000474228;ENST00000426832;ENST00000440972;MSTRG.15668.10	NA	NA	NA	NA	NA	2.49	2.53	2.95	13.04	10.39	6.06	0.29	-1.77	0.02	0.25	down	yes
MSTRG.15675	ETAA1	ENST00000272342;ENST00000462772	GO:0005737(cytoplasm)	NA	NA	NA	Ewing tumor-associated antigen 1 [Source:HGNC Symbol;Acc:HGNC:24648]	1.01	1.33	1.41	4.03	2.75	1.61	0.49	-1.03	0.03	0.3	down	yes
MSTRG.15690	GFPT1	ENST00000357308;ENST00000361060;ENST00000494201	GO:0004360(glutamine-fructose-6-phosphate transaminase (isomerizing) activity);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0006112(energy reserve metabolic process);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006541(glutamine metabolic process);GO:0008152(metabolic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030246(carbohydrate binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032922(circadian regulation of gene expression);GO:0036498(IRE1-mediated unfolded protein response);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0070062(extracellular exosome);GO:1901137(carbohydrate derivative biosynthetic process)	"00250(Alanine, aspartate and glutamate metabolism);00520(Amino sugar and nucleotide sugar metabolism);01100(Metabolic pathways)"	NA	NA	glutamine--fructose-6-phosphate transaminase 1 [Source:HGNC Symbol;Acc:HGNC:4241]	30.41	33.76	20.56	6.97	6.65	5.21	3.66	1.87	0.01	0.23	up	yes
MSTRG.15720	TEX261	ENST00000606025;ENST00000422761;ENST00000272438;ENST00000478068;ENST00000433258;ENST00000466731;ENST00000489894;ENST00000473055	GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030134(ER to Golgi transport vesicle);GO:0030173(integral component of Golgi membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0097020(COPII adaptor activity)	NA	NA	NA	testis expressed 261 [Source:HGNC Symbol;Acc:HGNC:30712]	9.66	8.66	10.89	24.39	24.4	16.64	0.45	-1.15	0.02	0.27	down	yes
MSTRG.15740	DYSF	ENST00000409582;ENST00000394120;ENST00000409366;ENST00000409651;ENST00000409744;ENST00000410020;ENST00000410041;ENST00000472873;ENST00000487180	GO:0001778(plasma membrane repair);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005886(plasma membrane);GO:0006906(vesicle fusion);GO:0016021(integral component of membrane);GO:0030027(lamellipodium);GO:0030139(endocytic vesicle);GO:0030315(T-tubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0042383(sarcolemma);GO:0070062(extracellular exosome)	NA	NA	NA	dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]	1.65	1.39	1.75	0.22	0.15	0.21	2.37	1.25	0	0.13	up	yes
MSTRG.15741	CYP26B1	ENST00000001146;MSTRG.15741.3;ENST00000474509;ENST00000461519	"GO:0001709(cell fate determination);GO:0001768(establishment of T cell polarity);GO:0001972(retinoic acid binding);GO:0004497(monooxygenase activity);GO:0005506(iron ion binding);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0006766(vitamin metabolic process);GO:0006805(xenobiotic metabolic process);GO:0006954(inflammatory response);GO:0007140(male meiosis);GO:0007283(spermatogenesis);GO:0008401(retinoic acid 4-hydroxylase activity);GO:0009954(proximal/distal pattern formation);GO:0010628(positive regulation of gene expression);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0030326(embryonic limb morphogenesis);GO:0034653(retinoic acid catabolic process);GO:0042573(retinoic acid metabolic process);GO:0043587(tongue morphogenesis);GO:0044281(small molecule metabolic process);GO:0045580(regulation of T cell differentiation);GO:0048384(retinoic acid receptor signaling pathway);GO:0048385(regulation of retinoic acid receptor signaling pathway);GO:0048387(negative regulation of retinoic acid receptor signaling pathway);GO:0055114(oxidation-reduction process);GO:0060349(bone morphogenesis);GO:0061436(establishment of skin barrier);GO:0070268(cornification);GO:0071300(cellular response to retinoic acid);GO:2001037(positive regulation of tongue muscle cell differentiation)"	00830(Retinol metabolism)	NA	NA	"cytochrome P450, family 26, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:20581]"	0.73	0.76	1.12	4.17	3.15	2.54	0.39	-1.35	0.01	0.21	down	yes
MSTRG.15759	ALMS1-IT1	ENST00000441587	NA	NA	NA	NA	NA	2.01	2.37	1.21	0.41	0.36	0.13	2.01	1.01	0.04	0.31	up	yes
MSTRG.15774	MTHFD2	MSTRG.15774.1;ENST00000394053;ENST00000409804;ENST00000470592;ENST00000477455;ENST00000489041;ENST00000409601;ENST00000488086;ENST00000462026	GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0005615(extracellular space);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0009396(folic acid-containing compound biosynthetic process);GO:0042301(phosphate ion binding);GO:0046653(tetrahydrofolate metabolic process);GO:0055114(oxidation-reduction process)	NA	NA	NA	"methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]"	114.42	121.29	98.53	15.56	18.88	17.23	6.28	2.65	0	0.11	up	yes
MSTRG.15783	RTKN	ENST00000305557;MSTRG.15783.3;ENST00000233330;ENST00000492013;ENST00000469859;ENST00000472518;ENST00000464094;ENST00000460968;ENST00000484453	GO:0005095(GTPase inhibitor activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0017048(Rho GTPase binding);GO:0017049(GTP-Rho binding);GO:0032185(septin cytoskeleton organization);GO:0034260(negative regulation of GTPase activity)	NA	NA	NA	rhotekin [Source:HGNC Symbol;Acc:HGNC:10466]	3.39	3.06	2.51	8.58	8.61	7.9	0.43	-1.21	0	0.17	down	yes
MSTRG.15784	WBP1	MSTRG.15784.2;MSTRG.15784.1;ENST00000233331;MSTRG.15784.4;MSTRG.15784.5;MSTRG.15784.7;MSTRG.15784.6;ENST00000431187;ENST00000452361;ENST00000494986;ENST00000441673;ENST00000409917;ENST00000471577;ENST00000473618;ENST00000409493;ENST00000469849;ENST00000455562;ENST00000233615;ENST00000393972;ENST00000474185;ENST00000466835;ENST00000464774;ENST00000470536;ENST00000484744;ENST00000409737;ENST00000428943;ENST00000494741;ENST00000473467;ENST00000466303;ENST00000492047;ENST00000490120	GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0050699(WW domain binding)	NA	NA	NA	WW domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12737]	34.07	32.72	28.24	12.8	11.11	22.07	2.37	1.25	0.05	0.34	up	yes
MSTRG.15785	MOGS	ENST00000233616;ENST00000452063;ENST00000409065;ENST00000462189;ENST00000448666;ENST00000462443;ENST00000489655;ENST00000486036	GO:0003824(catalytic activity);GO:0004573(mannosyl-oligosaccharide glucosidase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006457(protein folding);GO:0006487(protein N-linked glycosylation);GO:0009311(oligosaccharide metabolic process);GO:0015926(glucosidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018279(protein N-linked glycosylation via asparagine);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0070062(extracellular exosome)	00510(N-Glycan biosynthesis);01100(Metabolic pathways);04141(Protein processing in endoplasmic reticulum)	NA	NA	mannosyl-oligosaccharide glucosidase [Source:HGNC Symbol;Acc:HGNC:24862]	48.65	48.97	46.99	16.91	15.88	26.51	2.67	1.42	0.02	0.25	up	yes
MSTRG.15787	TTC31	MSTRG.15787.1;ENST00000489152;ENST00000424122;ENST00000442235;ENST00000449459;ENST00000464241;ENST00000410003;ENST00000463704;ENST00000491252;ENST00000233623;ENST00000459957;ENST00000463189;ENST00000487623;ENST00000414247	GO:0005515(protein binding)	NA	NA	NA	tetratricopeptide repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:25759]	2.39	2.35	3.39	5.71	9.47	6.64	0.47	-1.08	0.04	0.33	down	yes
MSTRG.15792	PCGF1	ENST00000465993;ENST00000475863;ENST00000233630;ENST00000489914;ENST00000612049;ENST00000480844;ENST00000463744;ENST00000496911	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008022(protein C-terminus binding);GO:0008270(zinc ion binding);GO:0031519(PcG protein complex);GO:0035518(histone H2A monoubiquitination);GO:0046872(metal ion binding)"	NA	NA	NA	polycomb group ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17615]	37.56	28.04	19.35	7.14	8.03	9.5	3.7	1.89	0.01	0.23	up	yes
MSTRG.15799	HK2	ENST00000290573;MSTRG.15799.2;ENST00000409174;ENST00000472302	"GO:0001678(cellular glucose homeostasis);GO:0002931(response to ischemia);GO:0004340(glucokinase activity);GO:0004396(hexokinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005536(glucose binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006096(glycolytic process);GO:0007595(lactation);GO:0008637(apoptotic mitochondrial changes);GO:0008645(hexose transport);GO:0008865(fructokinase activity);GO:0015758(glucose transport);GO:0016020(membrane);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0019158(mannokinase activity);GO:0035795(negative regulation of mitochondrial membrane permeability);GO:0044281(small molecule metabolic process);GO:0046324(regulation of glucose import);GO:0046835(carbohydrate phosphorylation);GO:0051156(glucose 6-phosphate metabolic process);GO:0055085(transmembrane transport);GO:0061621(canonical glycolysis);GO:2000378(negative regulation of reactive oxygen species metabolic process)"	00010(Glycolysis / Gluconeogenesis);00051(Fructose and mannose metabolism);00052(Galactose metabolism);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00524(Butirosin and neomycin biosynthesis);01100(Metabolic pathways);04910(Insulin signaling pathway);04930(Type II diabetes mellitus);04973(Carbohydrate digestion and absorption)	NA	NA	hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]	38.54	49.72	53.61	6.24	9.11	20.95	4.91	2.29	0.04	0.32	up	yes
MSTRG.1582	ZNF697	MSTRG.1582.1;ENST00000421812	"GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008150(biological_process);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 697 [Source:HGNC Symbol;Acc:HGNC:32034]	11.61	12.17	9.71	0.39	2.69	0.14	6.69	2.74	0.04	0.31	up	yes
MSTRG.15822	AC013262.1	MSTRG.15822.2;MSTRG.15822.3;MSTRG.15822.1;MSTRG.15822.4	NA	NA	NA	NA	NA	7.29	6.5	7.27	3.26	2.85	2.77	2.02	1.02	0	0.16	up	yes
MSTRG.15834	KCMF1	ENST00000456682;ENST00000409785;ENST00000428691;ENST00000453448	GO:0008152(metabolic process);GO:0008270(zinc ion binding);GO:0016874(ligase activity);GO:0046872(metal ion binding)	NA	NA	NA	potassium channel modulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:20589]	32.85	32.31	25.53	11.3	13.16	8.11	2.54	1.34	0.02	0.27	up	yes
MSTRG.15849	CAPG	ENST00000263867;ENST00000453973;MSTRG.15849.2;ENST00000409921;MSTRG.15849.5;ENST00000409724;ENST00000471064;ENST00000483659;ENST00000439385;ENST00000449030;ENST00000447219;ENST00000459793;ENST00000409275;ENST00000415012;ENST00000491267	GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0006461(protein complex assembly);GO:0008290(F-actin capping protein complex);GO:0019904(protein domain specific binding);GO:0030031(cell projection assembly);GO:0032403(protein complex binding);GO:0042470(melanosome);GO:0051016(barbed-end actin filament capping);GO:0070062(extracellular exosome);GO:0072686(mitotic spindle);GO:0090543(Flemming body)	NA	NA	NA	"capping protein (actin filament), gelsolin-like [Source:HGNC Symbol;Acc:HGNC:1474]"	10.34	9.35	7.79	1.54	1.42	1.84	4.21	2.07	0	0.13	up	yes
MSTRG.15859	TMEM150A	ENST00000306353;ENST00000431593;ENST00000334462;ENST00000444380;ENST00000409668;ENST00000463363;ENST00000422458;ENST00000451147;ENST00000417791;ENST00000433956;ENST00000455852	GO:0005515(protein binding);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0009056(catabolic process);GO:0010506(regulation of autophagy);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 150A [Source:HGNC Symbol;Acc:HGNC:24677]	5.27	3.36	5.49	1.42	1.25	2.66	2.55	1.35	0.02	0.26	up	yes
MSTRG.15862	ATOH8	MSTRG.15862.1	NA	NA	NA	NA	NA	0	0	0	1.25	1.07	2.35	0.44	-1.19	0.02	0.28	down	yes
MSTRG.15865	ST3GAL5	MSTRG.15865.1;ENST00000393805;ENST00000377332;ENST00000461206;ENST00000306262;ENST00000455892;ENST00000433665;ENST00000487896;ENST00000461892;ENST00000484728	"GO:0000139(Golgi membrane);GO:0001574(ganglioside biosynthetic process);GO:0004513(neolactotetraosylceramide alpha-2,3-sialyltransferase activity);GO:0005887(integral component of plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006688(glycosphingolipid biosynthetic process);GO:0008373(sialyltransferase activity);GO:0016021(integral component of membrane);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030173(integral component of Golgi membrane);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0047291(lactosylceramide alpha-2,3-sialyltransferase activity);GO:0097503(sialylation)"	00604(Glycosphingolipid biosynthesis - ganglio series);01100(Metabolic pathways)	NA	NA	"ST3 beta-galactoside alpha-2,3-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:10872]"	1.64	1.19	0.94	4.21	2.92	4.63	0.49	-1.03	0.03	0.3	down	yes
MSTRG.15883	AC125232.1	MSTRG.15883.1;ENST00000452554	NA	NA	NA	NA	NA	18.73	21.56	15.23	4.42	3.76	6.6	3.45	1.79	0.01	0.24	up	yes
MSTRG.15886	KRCC1	ENST00000347055	GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	NA	NA	NA	lysine-rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28039]	2.18	2.44	4.19	10.36	8.57	4.63	0.36	-1.46	0.05	0.34	down	yes
MSTRG.15910	.	MSTRG.15910.1;MSTRG.15910.2;MSTRG.15910.3;MSTRG.15910.4	NA	NA	NA	NA	NA	5.04	4.27	3.95	1.79	1.42	1.84	2.12	1.08	0.01	0.19	up	yes
MSTRG.15911	.	MSTRG.15911.1	NA	NA	NA	NA	NA	1.18	0.92	2.05	0.06	0.22	0.19	2.16	1.11	0.03	0.29	up	yes
MSTRG.15928	STARD7	ENST00000337288;ENST00000479456;ENST00000462501;ENST00000443962;ENST00000495687;ENST00000488084	GO:0005739(mitochondrion);GO:0008289(lipid binding);GO:1903955(positive regulation of protein targeting to mitochondrion)	NA	NA	NA	StAR-related lipid transfer (START) domain containing 7 [Source:HGNC Symbol;Acc:HGNC:18063]	28.78	36.14	14.56	85.76	86.75	72.81	0.29	-1.8	0.05	0.33	down	yes
MSTRG.15930	TMEM127	ENST00000258439;MSTRG.15930.2;MSTRG.15930.3;MSTRG.15930.4;ENST00000432959;ENST00000435268	GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0007032(endosome organization);GO:0008285(negative regulation of cell proliferation);GO:0016021(integral component of membrane);GO:0017137(Rab GTPase binding);GO:0032006(regulation of TOR signaling);GO:0032007(negative regulation of TOR signaling)	NA	NA	NA	transmembrane protein 127 [Source:HGNC Symbol;Acc:HGNC:26038]	0.59	9.45	3.28	13.9	11.97	8.52	0.16	-2.66	0.01	0.24	down	yes
MSTRG.15933	NCAPH	MSTRG.15933.1;ENST00000240423;ENST00000427946;ENST00000477409;ENST00000435975;ENST00000456906;ENST00000455200;ENST00000435349	GO:0000278(mitotic cell cycle);GO:0000796(condensin complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007076(mitotic chromosome condensation);GO:0016020(membrane);GO:0051301(cell division)	NA	NA	NA	"non-SMC condensin I complex, subunit H [Source:HGNC Symbol;Acc:HGNC:1112]"	1.6	1.25	0.62	26.33	25.99	10.3	0.09	-3.46	0.01	0.23	down	yes
MSTRG.15935	ARID5A	ENST00000470579;ENST00000357485;ENST00000412735;ENST00000467498;ENST00000454558;ENST00000497920	"GO:0002062(chondrocyte differentiation);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0035066(positive regulation of histone acetylation);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	AT rich interactive domain 5A (MRF1-like) [Source:HGNC Symbol;Acc:HGNC:17361]	12.18	9.04	8.43	3.64	4.26	7.95	2.32	1.21	0.03	0.28	up	yes
MSTRG.15961	COA5	ENST00000328709;ENST00000483527;ENST00000466848;ENST00000480666;ENST00000409997	GO:0005515(protein binding);GO:0005739(mitochondrion)	NA	NA	NA	cytochrome c oxidase assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:33848]	4.29	5.08	6.87	1.76	1.91	2.36	2.09	1.06	0.03	0.29	up	yes
MSTRG.15996	IL18R1	ENST00000404917;ENST00000473175;ENST00000311734;ENST00000409584;ENST00000482701;ENST00000427077;MSTRG.15996.12;MSTRG.15996.11;MSTRG.15996.14;MSTRG.15996.13;ENST00000409599;ENST00000466357;ENST00000233957;ENST00000334376	GO:0004872(receptor activity);GO:0004908(interleukin-1 receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0016021(integral component of membrane);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0035655(interleukin-18-mediated signaling pathway);GO:0042008(interleukin-18 receptor activity);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0045063(T-helper 1 cell differentiation)	04060(Cytokine-cytokine receptor interaction)	NA	NA	interleukin 18 receptor 1 [Source:HGNC Symbol;Acc:HGNC:5988]	3.41	5.05	5.66	0.59	0.59	0.25	3.42	1.78	0	0.17	up	yes
MSTRG.16022	UXS1	MSTRG.16022.1;ENST00000283148;ENST00000497604;ENST00000409501;ENST00000473338;ENST00000409032;ENST00000470053;ENST00000441952;ENST00000416298;ENST00000444193;ENST00000457835;ENST00000436241;ENST00000479774;ENST00000479621;ENST00000483426;ENST00000474920	GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0005794(Golgi apparatus);GO:0008152(metabolic process);GO:0016021(integral component of membrane);GO:0032580(Golgi cisterna membrane);GO:0033320(UDP-D-xylose biosynthetic process);GO:0042803(protein homodimerization activity);GO:0048040(UDP-glucuronate decarboxylase activity);GO:0050662(coenzyme binding);GO:0051262(protein tetramerization);GO:0070062(extracellular exosome);GO:0070403(NAD+ binding)	00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism);01100(Metabolic pathways)	NA	NA	UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]	4.81	5.04	8.4	18.26	15.21	19.71	0.36	-1.46	0.03	0.28	down	yes
MSTRG.16036	LIMS1	ENST00000544547;ENST00000428064;MSTRG.16036.3;MSTRG.16036.4;ENST00000332345;ENST00000393310;ENST00000410093;ENST00000449684;ENST00000409441;ENST00000422797;ENST00000338045;ENST00000474038;ENST00000462817;ENST00000496653;ENST00000414829;ENST00000434274;MSTRG.16036.17;ENST00000542845	"GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007569(cell aging);GO:0008270(zinc ion binding);GO:0010628(positive regulation of gene expression);GO:0010811(positive regulation of cell-substrate adhesion);GO:0019901(protein kinase binding);GO:0034329(cell junction assembly);GO:0043547(positive regulation of GTPase activity);GO:0045184(establishment of protein localization);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048471(perinuclear region of cytoplasm);GO:0051894(positive regulation of focal adhesion assembly);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)"	NA	NA	NA	LIM and senescent cell antigen-like domains 1 [Source:HGNC Symbol;Acc:HGNC:6616]	7.13	7.75	6.21	2.44	2.54	4.73	2.15	1.1	0.05	0.33	up	yes
MSTRG.16059	BCL2L11	ENST00000432179;ENST00000337565;ENST00000357757;ENST00000308659;ENST00000615946;ENST00000619294;ENST00000620862;ENST00000621302;ENST00000622509;ENST00000622612;ENST00000393256;ENST00000393252;MSTRG.16059.13;ENST00000433098;ENST00000405953;ENST00000361493;ENST00000437029;ENST00000452231;ENST00000431217	GO:0001701(in utero embryonic development);GO:0001776(leukocyte homeostasis);GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001822(kidney development);GO:0002260(lymphocyte homeostasis);GO:0002262(myeloid cell homeostasis);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0005874(microtubule);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007160(cell-matrix adhesion);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008017(microtubule binding);GO:0008584(male gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009791(post-embryonic development);GO:0010942(positive regulation of cell death);GO:0012501(programmed cell death);GO:0012505(endomembrane system);GO:0019898(extrinsic component of membrane);GO:0030879(mammary gland development);GO:0032464(positive regulation of protein homooligomerization);GO:0034976(response to endoplasmic reticulum stress);GO:0035148(tube formation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042981(regulation of apoptotic process);GO:0043029(T cell homeostasis);GO:0043065(positive regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045787(positive regulation of cell cycle);GO:0046620(regulation of organ growth);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048563(post-embryonic organ morphogenesis);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070242(thymocyte apoptotic process);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097140(BIM-BCL-xl complex);GO:0097141(BIM-BCL-2 complex);GO:0097190(apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)	NA	NA	NA	BCL2-like 11 (apoptosis facilitator) [Source:HGNC Symbol;Acc:HGNC:994]	3.91	3.37	2.51	0.38	1.59	1.22	2.57	1.36	0.03	0.29	up	yes
MSTRG.16082	RP11-399B17.1	MSTRG.16082.1	NA	NA	NA	NA	NA	0.23	1.08	0.52	2.09	1.39	2.45	0.45	-1.14	0.04	0.31	down	yes
MSTRG.16094	RP11-67L14.1	MSTRG.16094.1	NA	NA	NA	NA	NA	0.17	0.18	0.14	2.64	1.29	1.61	0.38	-1.41	0.01	0.23	down	yes
MSTRG.16133	TMEM177	ENST00000401466;ENST00000424086;MSTRG.16133.1;ENST00000272521;ENST00000445518;ENST00000496203;ENST00000409951	GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 177 [Source:HGNC Symbol;Acc:HGNC:28143]	0.92	1.05	1.61	4.42	4.33	2.9	0.4	-1.31	0.01	0.24	down	yes
MSTRG.16148	RP11-297J22.1	MSTRG.16148.1;MSTRG.16148.2;ENST00000603720	NA	NA	NA	NA	NA	1.29	1.81	2	0.15	0.23	0.15	2.12	1.08	0	0.19	up	yes
MSTRG.1616	.	MSTRG.1616.1	NA	NA	NA	NA	NA	1.63	1.19	1.07	0.18	0.19	0.13	2.08	1.06	0	0.18	up	yes
MSTRG.16242	MCM6	ENST00000264156;ENST00000492091;ENST00000483902	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0042555(MCM complex);GO:0042802(identical protein binding)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949]	16.17	21.92	15.71	53.57	43.93	27.7	0.35	-1.5	0.01	0.23	down	yes
MSTRG.163	DNAJC11	ENST00000465508;ENST00000451196;ENST00000377577;ENST00000294401;ENST00000472414;ENST00000426784;ENST00000473993;ENST00000469318;ENST00000485073;ENST00000460594;ENST00000465911	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070062(extracellular exosome)	NA	NA	NA	"DnaJ (Hsp40) homolog, subfamily C, member 11 [Source:HGNC Symbol;Acc:HGNC:25570]"	4.54	6.12	8.27	16.35	18.56	13.87	0.37	-1.45	0.02	0.25	down	yes
MSTRG.16303	LYPD6	ENST00000334166;ENST00000414420;ENST00000392854	GO:0005576(extracellular region)	NA	NA	NA	LY6/PLAUR domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28751]	0.1	0.3	0.26	1.48	1.12	1.02	0.48	-1.05	0	0.1	down	yes
MSTRG.16310	RND3	ENST00000375734;ENST00000263895;ENST00000409557;ENST00000497865;ENST00000473639;ENST00000466334;ENST00000472416;ENST00000454202;ENST00000439275	GO:0000139(Golgi membrane);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0030036(actin cytoskeleton organization);GO:0070062(extracellular exosome)	NA	NA	NA	Rho family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:671]	52.46	55.83	51.98	18.07	14.01	6.55	3.28	1.72	0.03	0.3	up	yes
MSTRG.16386	IFIH1	ENST00000263642;ENST00000421365	"GO:0003677(DNA binding);GO:0003725(double-stranded RNA binding);GO:0003727(single-stranded RNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0009597(detection of virus);GO:0009615(response to virus);GO:0016032(viral process);GO:0016787(hydrolase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0016925(protein sumoylation);GO:0032480(negative regulation of type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0034344(regulation of type III interferon production);GO:0039528(cytoplasmic pattern recognition receptor signaling pathway in response to virus);GO:0042981(regulation of apoptotic process);GO:0043021(ribonucleoprotein complex binding);GO:0045087(innate immune response)"	04622(RIG-I-like receptor signaling pathway);05162(Measles);05164(Influenza A)	NA	NA	interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873]	3.75	3.74	5.38	1	0.43	0.89	2.94	1.55	0.01	0.24	up	yes
MSTRG.16405	SPC25	ENST00000479309;MSTRG.16405.2;ENST00000282074;ENST00000472216	GO:0000278(mitotic cell cycle);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0007052(mitotic spindle organization);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0031262(Ndc80 complex);GO:0051301(cell division)	NA	NA	NA	"SPC25, NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:24031]"	0.45	0.25	0.11	17.73	20.04	8.19	0.07	-3.75	0.01	0.2	down	yes
MSTRG.16423	ERICH2	MSTRG.16423.2;MSTRG.16423.1;MSTRG.16423.4;MSTRG.16423.3;ENST00000426475;ENST00000409885	GO:0005515(protein binding)	NA	NA	NA	glutamate-rich 2 [Source:HGNC Symbol;Acc:HGNC:44395]	4	3.93	3.69	0.47	0.21	0.95	3.42	1.78	0.01	0.21	up	yes
MSTRG.16471	CHN1	MSTRG.16471.1;ENST00000409900;MSTRG.16471.3;ENST00000295497;ENST00000488080;ENST00000492964;ENST00000409156;ENST00000409089;ENST00000444394;ENST00000443238;ENST00000491801;ENST00000485882;ENST00000444573;ENST00000481174;ENST00000451799	GO:0005070(SH3/SH2 adaptor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008045(motor neuron axon guidance);GO:0009967(positive regulation of signal transduction);GO:0035556(intracellular signal transduction);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0051056(regulation of small GTPase mediated signal transduction)	NA	NA	NA	chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]	3.19	2.29	2.16	8.28	6.55	7.53	0.44	-1.19	0.01	0.23	down	yes
MSTRG.16505	HNRNPA3	ENST00000392524;ENST00000411529;ENST00000435711;ENST00000432457;ENST00000483137	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030529(ribonucleoprotein complex);GO:0035770(ribonucleoprotein granule);GO:0043005(neuron projection);GO:0044822(poly(A) RNA binding);GO:0051028(mRNA transport);GO:0051033(RNA transmembrane transporter activity);GO:0071013(catalytic step 2 spliceosome)"	03040(Spliceosome)	NA	NA	heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941]	25.43	27.07	19.04	68.72	64.29	36.26	0.38	-1.4	0.04	0.33	down	yes
MSTRG.16548	ITGA4	ENST00000476089;ENST00000339307;ENST00000397033;MSTRG.16548.3;ENST00000465522;ENST00000233573;ENST00000484404;ENST00000478440;ENST00000473002;ENST00000490435;ENST00000476824;ENST00000468948	GO:0001968(fibronectin binding);GO:0001974(blood vessel remodeling);GO:0002687(positive regulation of leukocyte migration);GO:0003366(cell-matrix adhesion involved in ameboidal cell migration);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0007159(leukocyte cell-cell adhesion);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007507(heart development);GO:0007596(blood coagulation);GO:0008305(integrin complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016020(membrane);GO:0016477(cell migration);GO:0030183(B cell differentiation);GO:0030198(extracellular matrix organization);GO:0034113(heterotypic cell-cell adhesion);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034669(integrin alpha4-beta7 complex);GO:0035987(endodermal cell differentiation);GO:0043113(receptor clustering);GO:0046872(metal ion binding);GO:0050776(regulation of immune response);GO:0050839(cell adhesion molecule binding);GO:0050900(leukocyte migration);GO:0050901(leukocyte tethering or rolling);GO:0050904(diapedesis);GO:0060324(face development);GO:0060710(chorio-allantoic fusion);GO:0070062(extracellular exosome);GO:0071345(cellular response to cytokine stimulus);GO:0072678(T cell migration);GO:0090074(negative regulation of protein homodimerization activity);GO:0098657(import into cell);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1990405(protein antigen binding);GO:2000406(positive regulation of T cell migration)	NA	NA	NA	"integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) [Source:HGNC Symbol;Acc:HGNC:6140]"	2.7	2.5	1.75	11.14	9.88	4.37	0.31	-1.68	0.05	0.34	down	yes
MSTRG.16555	NUP35	ENST00000409798;ENST00000472844;ENST00000295119;ENST00000497330;ENST00000374930;ENST00000479162	GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005652(nuclear lamina);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0007077(mitotic nuclear envelope disassembly);GO:0008645(hexose transport);GO:0010467(gene expression);GO:0010827(regulation of glucose transport);GO:0015031(protein transport);GO:0015758(glucose transport);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019221(cytokine-mediated signaling pathway);GO:0031965(nuclear membrane);GO:0034605(cellular response to heat);GO:0043231(intracellular membrane-bounded organelle);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0045111(intermediate filament cytoskeleton);GO:0051028(mRNA transport);GO:0055085(transmembrane transport);GO:1900034(regulation of cellular response to heat)	03013(RNA transport)	NA	NA	nucleoporin 35kDa [Source:HGNC Symbol;Acc:HGNC:29797]	1.66	2.31	1.95	4.97	5.69	3.11	0.46	-1.14	0.02	0.27	down	yes
MSTRG.16564	.	MSTRG.16564.1	NA	NA	NA	NA	NA	1.72	2.38	1.38	0.22	0.34	0.11	2.11	1.08	0.01	0.24	up	yes
MSTRG.16644	MOB4	ENST00000233893;ENST00000409729;ENST00000473395;ENST00000409468;ENST00000604458;ENST00000495200;ENST00000465573;ENST00000463841;ENST00000233892;ENST00000323303;ENST00000448447;ENST00000497443;ENST00000417097;ENST00000409355;ENST00000409360	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006810(transport);GO:0016020(membrane);GO:0019900(kinase binding);GO:0032580(Golgi cisterna membrane);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm)	NA	NA	NA	"MOB family member 4, phocein [Source:HGNC Symbol;Acc:HGNC:17261]"	19.38	19.59	17.03	41.94	44.37	26.63	0.47	-1.09	0.04	0.32	down	yes
MSTRG.16664	CLK1	ENST00000321356;ENST00000621181;ENST00000461981;MSTRG.16664.3;ENST00000464454;MSTRG.16664.5;ENST00000432425;ENST00000473565;ENST00000472679;ENST00000409769;ENST00000409403;ENST00000434813;ENST00000461326;ENST00000496205;ENST00000492793;ENST00000481641;ENST00000482590	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0008283(cell proliferation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043484(regulation of RNA splicing);GO:0046777(protein autophosphorylation)"	NA	NA	NA	CDC-like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2068]	16.27	14.97	9.51	5.34	3.48	2.68	2.74	1.45	0.05	0.33	up	yes
MSTRG.16673	NIF3L1	ENST00000426253;MSTRG.16673.1;MSTRG.16673.3;MSTRG.16673.4;MSTRG.16673.5;ENST00000454952;ENST00000409020;ENST00000359683;ENST00000409357;ENST00000409129;ENST00000416651;ENST00000409588;ENST00000436412	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0008134(transcription factor binding);GO:0030182(neuron differentiation);GO:0042802(identical protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:1903507(negative regulation of nucleic acid-templated transcription)"	NA	K01495;K09007	3.5.4.16	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:13390]	3.34	4.51	5.82	10.82	11.36	6.94	0.43	-1.21	0.03	0.29	down	yes
MSTRG.16680	NDUFB3	ENST00000450023;ENST00000237889;ENST00000433898;ENST00000454214	"GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0016021(integral component of membrane);GO:0022900(electron transport chain);GO:0022904(respiratory electron transport chain);GO:0044237(cellular metabolic process);GO:0044281(small molecule metabolic process);GO:0070062(extracellular exosome)"	00190(Oxidative phosphorylation);01100(Metabolic pathways);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease)	NA	NA	"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa [Source:HGNC Symbol;Acc:HGNC:7698]"	27.74	31.52	26.52	59.41	58.52	41.29	0.49	-1.03	0.01	0.24	down	yes
MSTRG.16687	CASP8	ENST00000392263;ENST00000264274;ENST00000432109;ENST00000490682;MSTRG.16687.5;ENST00000471383;MSTRG.16687.7;ENST00000440732;ENST00000392258;ENST00000358485;MSTRG.16687.14;MSTRG.16687.15;MSTRG.16687.16;MSTRG.16687.17;MSTRG.16687.18;MSTRG.16687.19;ENST00000392266;ENST00000437283;ENST00000413726;ENST00000339403;ENST00000323492;ENST00000429881;ENST00000424461;ENST00000444430	"GO:0001525(angiogenesis);GO:0001841(neural tube formation);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002224(toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0004175(endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity);GO:0005123(death receptor binding);GO:0005164(tumor necrosis factor receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006921(cellular component disassembly involved in execution phase of apoptosis);GO:0007166(cell surface receptor signaling pathway);GO:0007507(heart development);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009409(response to cold);GO:0010939(regulation of necrotic cell death);GO:0012501(programmed cell death);GO:0016032(viral process);GO:0030101(natural killer cell activation);GO:0030225(macrophage differentiation);GO:0030690(Noc1p-Noc2p complex);GO:0031264(death-inducing signaling complex);GO:0031265(CD95 death-inducing signaling complex);GO:0031625(ubiquitin protein ligase binding);GO:0032025(response to cobalt ion);GO:0032355(response to estradiol);GO:0032403(protein complex binding);GO:0032496(response to lipopolysaccharide);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034612(response to tumor necrosis factor);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:0035877(death effector domain binding);GO:0036462(TRAIL-activated apoptotic signaling pathway);GO:0042110(T cell activation);GO:0042113(B cell activation);GO:0042981(regulation of apoptotic process);GO:0043005(neuron projection);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043234(protein complex);GO:0044297(cell body);GO:0045087(innate immune response);GO:0045121(membrane raft);GO:0045471(response to ethanol);GO:0045651(positive regulation of macrophage differentiation);GO:0045862(positive regulation of proteolysis);GO:0046677(response to antibiotic);GO:0046982(protein heterodimerization activity);GO:0051291(protein heterooligomerization);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0060546(negative regulation of necroptotic process);GO:0060715(syncytiotrophoblast cell differentiation involved in labyrinthine layer development);GO:0070243(regulation of thymocyte apoptotic process);GO:0070266(necroptotic process);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071550(death-inducing signaling complex assembly);GO:0097110(scaffold protein binding);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097193(intrinsic apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:0097199(cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0097284(hepatocyte apoptotic process);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0097300(programmed necrotic cell death);GO:0097342(ripoptosome);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2001233(regulation of apoptotic signaling pathway);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)"	04115(p53 signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);05010(Alzheimer's disease);05016(Huntington's disease);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05152(Tuberculosis);05200(Pathways in cancer);05416(Viral myocarditis)	NA	NA	"caspase 8, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:1509]"	1.67	1.85	2.75	4.83	5.34	5.51	0.49	-1.04	0.02	0.26	down	yes
MSTRG.16717	NBEAL1	MSTRG.16717.1	NA	NA	NA	NA	NA	1.73	1.44	1.12	0.25	0.3	0.08	2.04	1.03	0.01	0.23	up	yes
MSTRG.16771	IDH1	MSTRG.16771.1;MSTRG.16771.2;ENST00000345146;ENST00000446179;ENST00000415913;ENST00000484575;ENST00000415282;ENST00000462386;ENST00000417583;ENST00000451391;ENST00000481557	"GO:0000287(magnesium ion binding);GO:0004450(isocitrate dehydrogenase (NADP+) activity);GO:0005102(receptor binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0005829(cytosol);GO:0006097(glyoxylate cycle);GO:0006099(tricarboxylic acid cycle);GO:0006102(isocitrate metabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0006740(NADPH regeneration);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0008585(female gonad development);GO:0014070(response to organic cyclic compound);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0042803(protein homodimerization activity);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0048545(response to steroid hormone);GO:0050661(NADP binding);GO:0051287(NAD binding);GO:0055114(oxidation-reduction process);GO:0060696(regulation of phospholipid catabolic process);GO:0070062(extracellular exosome);GO:0071071(regulation of phospholipid biosynthetic process)"	00020(Citrate cycle (TCA cycle));00480(Glutathione metabolism);01100(Metabolic pathways);04146(Peroxisome)	NA	NA	"isocitrate dehydrogenase 1 (NADP+), soluble [Source:HGNC Symbol;Acc:HGNC:5382]"	81.79	96.01	95.35	24.21	12.59	15.17	4.28	2.1	0.01	0.19	up	yes
MSTRG.16786	CPS1	MSTRG.16786.1;MSTRG.16786.2;ENST00000417946;ENST00000518043;ENST00000430249;ENST00000233072;ENST00000497163;ENST00000451903;ENST00000467353;ENST00000497121;ENST00000470791;ENST00000479988	GO:0000050(urea cycle);GO:0001889(liver development);GO:0003824(catalytic activity);GO:0004087(carbamoyl-phosphate synthase (ammonia) activity);GO:0004088(carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity);GO:0004175(endopeptidase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005543(phospholipid binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0005980(glycogen catabolic process);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0006508(proteolysis);GO:0006526(arginine biosynthetic process);GO:0006541(glutamine metabolic process);GO:0006807(nitrogen compound metabolic process);GO:0007494(midgut development);GO:0008152(metabolic process);GO:0009636(response to toxic substance);GO:0010043(response to zinc ion);GO:0014075(response to amine);GO:0016595(glutamate binding);GO:0019240(citrulline biosynthetic process);GO:0019433(triglyceride catabolic process);GO:0032094(response to food);GO:0032403(protein complex binding);GO:0032496(response to lipopolysaccharide);GO:0033762(response to glucagon);GO:0034201(response to oleic acid);GO:0034641(cellular nitrogen compound metabolic process);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0042645(mitochondrial nucleoid);GO:0043200(response to amino acid);GO:0043234(protein complex);GO:0044281(small molecule metabolic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045909(positive regulation of vasodilation);GO:0046209(nitric oxide metabolic process);GO:0046872(metal ion binding);GO:0048545(response to steroid hormone);GO:0050667(homocysteine metabolic process);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0055081(anion homeostasis);GO:0060416(response to growth hormone);GO:0070365(hepatocyte differentiation);GO:0070409(carbamoyl phosphate biosynthetic process);GO:0071320(cellular response to cAMP);GO:0071377(cellular response to glucagon stimulus);GO:0071400(cellular response to oleic acid);GO:0071548(response to dexamethasone);GO:0072341(modified amino acid binding)	"00250(Alanine, aspartate and glutamate metabolism);00330(Arginine and proline metabolism);00910(Nitrogen metabolism);01100(Metabolic pathways)"	NA	NA	"carbamoyl-phosphate synthase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:2323]"	1.8	2.03	1.76	5.25	4.37	4.08	0.48	-1.07	0	0.14	down	yes
MSTRG.16795	BARD1	ENST00000260947;ENST00000613706;ENST00000471590;ENST00000432456;ENST00000613192;ENST00000620057;ENST00000455743;ENST00000421162;ENST00000465841;ENST00000471787;ENST00000479904	GO:0000151(ubiquitin ligase complex);GO:0001894(tissue homeostasis);GO:0003723(RNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007050(cell cycle arrest);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0019900(kinase binding);GO:0031436(BRCA1-BARD1 complex);GO:0031441(negative regulation of mRNA 3'-end processing);GO:0042325(regulation of phosphorylation);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0045732(positive regulation of protein catabolic process);GO:0046826(negative regulation of protein export from nucleus);GO:0046982(protein heterodimerization activity);GO:0070531(BRCA1-A complex);GO:0085020(protein K6-linked ubiquitination)	NA	NA	NA	BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952]	0.59	1.19	0.64	3.35	2.65	1.27	0.42	-1.27	0.02	0.26	down	yes
MSTRG.1680	PRKAB2	MSTRG.1680.1;MSTRG.1680.2;MSTRG.1680.3;MSTRG.1680.4;ENST00000254101;ENST00000496858;ENST00000474939	GO:0004679(AMP-activated protein kinase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006112(energy reserve metabolic process);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0006633(fatty acid biosynthetic process);GO:0006853(carnitine shuttle);GO:0006996(organelle organization);GO:0007005(mitochondrion organization);GO:0007050(cell cycle arrest);GO:0007165(signal transduction);GO:0008286(insulin receptor signaling pathway);GO:0010467(gene expression);GO:0031588(AMP-activated protein kinase complex);GO:0042304(regulation of fatty acid biosynthetic process);GO:0042802(identical protein binding);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0045859(regulation of protein kinase activity);GO:0061024(membrane organization)	04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);05410(Hypertrophic cardiomyopathy (HCM))	NA	NA	"protein kinase, AMP-activated, beta 2 non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9379]"	17.73	10.32	16.57	3.71	2.06	2.13	4.57	2.19	0.02	0.25	up	yes
MSTRG.16811	IGFBP5	ENST00000233813;ENST00000486341;ENST00000449583	GO:0001558(regulation of cell growth);GO:0001649(osteoblast differentiation);GO:0001968(fibronectin binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006006(glucose metabolic process);GO:0007165(signal transduction);GO:0007565(female pregnancy);GO:0010906(regulation of glucose metabolic process);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016942(insulin-like growth factor binding protein complex);GO:0017148(negative regulation of translation);GO:0030336(negative regulation of cell migration);GO:0031069(hair follicle morphogenesis);GO:0031994(insulin-like growth factor I binding);GO:0031995(insulin-like growth factor II binding);GO:0035556(intracellular signal transduction);GO:0040008(regulation of growth);GO:0042567(insulin-like growth factor ternary complex);GO:0042593(glucose homeostasis);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0043569(negative regulation of insulin-like growth factor receptor signaling pathway);GO:0044267(cellular protein metabolic process);GO:0044342(type B pancreatic cell proliferation);GO:0045668(negative regulation of osteoblast differentiation);GO:0045926(negative regulation of growth);GO:0048286(lung alveolus development);GO:0048630(skeletal muscle tissue growth);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0051146(striated muscle cell differentiation);GO:0051897(positive regulation of protein kinase B signaling);GO:0060056(mammary gland involution);GO:0060416(response to growth hormone);GO:0071320(cellular response to cAMP);GO:0071407(cellular response to organic cyclic compound);GO:1901862(negative regulation of muscle tissue development);GO:1904205(negative regulation of skeletal muscle hypertrophy)	NA	NA	NA	insulin-like growth factor binding protein 5 [Source:HGNC Symbol;Acc:HGNC:5474]	1.45	0.99	0.23	34.03	17.92	54.9	0.06	-3.95	0.01	0.24	down	yes
MSTRG.16825	CTDSP1	ENST00000491064;ENST00000443891;ENST00000492545;ENST00000473420;MSTRG.16825.6;ENST00000273062;ENST00000497677;ENST00000494067;ENST00000452977;ENST00000428361;ENST00000496785;ENST00000431127;ENST00000488627;ENST00000482272	GO:0001933(negative regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006470(protein dephosphorylation);GO:0008420(CTD phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0045665(negative regulation of neuron differentiation);GO:0046872(metal ion binding);GO:0050768(negative regulation of neurogenesis);GO:0070062(extracellular exosome);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)	NA	NA	NA	"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614]"	1.8	1.66	4.5	10.06	9.67	13.83	0.3	-1.72	0.05	0.33	down	yes
MSTRG.16830	TMBIM1	MSTRG.16830.1;MSTRG.16830.2;MSTRG.16830.3;MSTRG.16830.4;ENST00000258412;ENST00000465082;ENST00000444881;ENST00000445635;ENST00000437694;ENST00000439306;ENST00000492966;ENST00000429501;ENST00000466012;ENST00000425694;ENST00000476429;ENST00000495113;ENST00000418569;ENST00000440422;ENST00000444183;ENST00000453776;ENST00000444000;ENST00000453281;ENST00000451181;ENST00000434015;ENST00000413976;ENST00000420341	GO:0005123(death receptor binding);GO:0005765(lysosomal membrane);GO:0005794(Golgi apparatus);GO:0010008(endosome membrane);GO:0016021(integral component of membrane);GO:0048553(negative regulation of metalloenzyme activity);GO:0070062(extracellular exosome);GO:0090005(negative regulation of establishment of protein localization to plasma membrane);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902045(negative regulation of Fas signaling pathway);GO:2000504(positive regulation of blood vessel remodeling)	NA	NA	NA	transmembrane BAX inhibitor motif containing 1 [Source:HGNC Symbol;Acc:HGNC:23410]	17.15	19.57	17.19	6.86	5.43	6.58	2.46	1.3	0	0.16	up	yes
MSTRG.16869	DNAJB2	ENST00000336576;ENST00000425450;ENST00000392086;ENST00000421532;ENST00000480537;ENST00000477917;ENST00000482988;ENST00000392087;ENST00000442681;ENST00000439026;ENST00000481815;ENST00000485220;ENST00000463463;ENST00000487855;ENST00000473750;ENST00000472019;ENST00000476254	GO:0000502(proteasome complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006457(protein folding);GO:0006986(response to unfolded protein);GO:0016234(inclusion body);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0030544(Hsp70 protein binding);GO:0031398(positive regulation of protein ubiquitination);GO:0031593(polyubiquitin binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042026(protein refolding);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0070628(proteasome binding);GO:0090084(negative regulation of inclusion body assembly);GO:0090086(negative regulation of protein deubiquitination)	04141(Protein processing in endoplasmic reticulum)	NA	NA	"DnaJ (Hsp40) homolog, subfamily B, member 2 [Source:HGNC Symbol;Acc:HGNC:5228]"	27.33	18.76	18.83	6.28	8.72	10.77	3.06	1.62	0	0.14	up	yes
MSTRG.16881	OBSL1	ENST00000462534;ENST00000465149;ENST00000404537;ENST00000373876;ENST00000603926;ENST00000604031;ENST00000472388;ENST00000373873;MSTRG.16881.12;ENST00000289656;ENST00000462385	GO:0000226(microtubule cytoskeleton organization);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0007010(cytoskeleton organization);GO:0007030(Golgi organization);GO:0007088(regulation of mitotic nuclear division);GO:0008093(cytoskeletal adaptor activity);GO:0014704(intercalated disc);GO:0030018(Z disc);GO:0031430(M band);GO:0034067(protein localization to Golgi apparatus);GO:0048471(perinuclear region of cytoplasm);GO:0050775(positive regulation of dendrite morphogenesis);GO:0055003(cardiac myofibril assembly);GO:1990393(3M complex)	NA	NA	NA	obscurin-like 1 [Source:HGNC Symbol;Acc:HGNC:29092]	2.43	2.41	2.89	10.04	10.84	14	0.31	-1.71	0	0.17	down	yes
MSTRG.16882	RP11-256I23.2	MSTRG.16882.1;ENST00000597192	NA	NA	NA	NA	NA	2.08	1.07	0.94	0.26	0.06	0.36	2.22	1.15	0.02	0.27	up	yes
MSTRG.16904	SCG2	ENST00000305409	GO:0000165(MAPK cascade);GO:0001525(angiogenesis);GO:0001937(negative regulation of endothelial cell proliferation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0009306(protein secretion);GO:0030141(secretory granule);GO:0035556(intracellular signal transduction);GO:0042056(chemoattractant activity);GO:0043542(endothelial cell migration);GO:0048245(eosinophil chemotaxis);GO:0050918(positive chemotaxis);GO:0050930(induction of positive chemotaxis);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)	NA	NA	NA	secretogranin II [Source:HGNC Symbol;Acc:HGNC:10575]	0.53	0.62	0.39	3.91	4.4	1.31	0.31	-1.69	0.05	0.33	down	yes
MSTRG.16906	AC012512.1	MSTRG.16906.1	NA	NA	NA	NA	NA	0.32	0.47	0.34	2.33	2.24	3.85	0.39	-1.37	0.01	0.24	down	yes
MSTRG.16909	WDFY1	ENST00000462702;ENST00000233055;ENST00000491453;ENST00000493001;ENST00000429915;ENST00000483061	GO:0005515(protein binding);GO:0005545(1-phosphatidylinositol binding);GO:0005634(nucleus);GO:0005769(early endosome);GO:0005829(cytosol);GO:0008150(biological_process);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)	NA	NA	NA	WD repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20451]	28.93	31.7	25.28	11.09	8.49	5.06	2.74	1.45	0.02	0.28	up	yes
MSTRG.16919	IRS1	ENST00000305123;ENST00000498335	GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0004871(signal transducer activity);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0005080(protein kinase C binding);GO:0005158(insulin receptor binding);GO:0005159(insulin-like growth factor receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005899(insulin receptor complex);GO:0005901(caveola);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0008286(insulin receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010468(regulation of gene expression);GO:0010907(positive regulation of glucose metabolic process);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0016042(lipid catabolic process);GO:0019901(protein kinase binding);GO:0030335(positive regulation of cell migration);GO:0030879(mammary gland development);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0034504(protein localization to nucleus);GO:0036064(ciliary basal body);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042169(SH2 domain binding);GO:0042593(glucose homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0043434(response to peptide hormone);GO:0043491(protein kinase B signaling);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045087(innate immune response);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0046326(positive regulation of glucose import);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0046676(negative regulation of insulin secretion);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:2001275(positive regulation of glucose import in response to insulin stimulus)	NA	NA	NA	insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125]	0.14	0.33	0.6	2.56	1.37	0.68	0.43	-1.23	0.04	0.31	down	yes
MSTRG.16932	DNER	MSTRG.16932.1;ENST00000341772;MSTRG.16932.3;MSTRG.16932.4;MSTRG.16932.5;ENST00000482831	GO:0001764(neuron migration);GO:0004888(transmembrane signaling receptor activity);GO:0005112(Notch binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0007219(Notch signaling pathway);GO:0007220(Notch receptor processing);GO:0007416(synapse assembly);GO:0007417(central nervous system development);GO:0010001(glial cell differentiation);GO:0016021(integral component of membrane);GO:0030276(clathrin binding);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0048741(skeletal muscle fiber development)	NA	NA	NA	delta/notch-like EGF repeat containing [Source:HGNC Symbol;Acc:HGNC:24456]	9.17	11.19	9.32	2.84	3.33	2.42	2.61	1.38	0	0.17	up	yes
MSTRG.16966	AC017104.6	MSTRG.16966.1;ENST00000415129;ENST00000418050;ENST00000454416	NA	NA	NA	NA	NA	1.81	0.9	1.24	4.24	4.23	4.22	0.5	-1	0.01	0.2	down	yes
MSTRG.16994	NGEF	ENST00000264051;ENST00000373552;ENST00000424488;ENST00000489127;ENST00000461944;ENST00000416114;ENST00000420650;ENST00000409079	GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007264(small GTPase mediated signal transduction);GO:0007411(axon guidance);GO:0009987(cellular process);GO:0016020(membrane);GO:0030426(growth cone);GO:0035023(regulation of Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0043087(regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0097190(apoptotic signaling pathway)	04360(Axon guidance)	NA	NA	neuronal guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:7807]	8.85	7.46	7.46	2.76	2.64	4.57	2.44	1.29	0.01	0.23	up	yes
MSTRG.17004	HJURP	ENST00000433484;ENST00000432087;ENST00000441687;ENST00000411486;MSTRG.17004.5;ENST00000414924;ENST00000434039;ENST00000453122;ENST00000373395	"GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006334(nucleosome assembly);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0034080(CENP-A containing nucleosome assembly);GO:0042393(histone binding);GO:0042802(identical protein binding);GO:0043254(regulation of protein complex assembly);GO:0051101(regulation of DNA binding)"	NA	NA	NA	Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444]	5.1	3.97	1.62	70.91	74.28	22.91	0.07	-3.78	0.03	0.28	down	yes
MSTRG.17101	DTYMK	ENST00000305784;MSTRG.17101.1;ENST00000400770;ENST00000445261;ENST00000432348;ENST00000420144;ENST00000493095;ENST00000464603	GO:0004798(thymidylate kinase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006227(dUDP biosynthetic process);GO:0006233(dTDP biosynthetic process);GO:0006235(dTTP biosynthetic process);GO:0007049(cell cycle);GO:0008283(cell proliferation);GO:0009041(uridylate kinase activity);GO:0009165(nucleotide biosynthetic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0043627(response to estrogen);GO:0044281(small molecule metabolic process);GO:0045445(myoblast differentiation);GO:0046686(response to cadmium ion);GO:0046939(nucleotide phosphorylation);GO:0046940(nucleoside monophosphate phosphorylation);GO:0050145(nucleoside phosphate kinase activity);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0071363(cellular response to growth factor stimulus)	00240(Pyrimidine metabolism);01100(Metabolic pathways)	NA	NA	deoxythymidylate kinase (thymidylate kinase) [Source:HGNC Symbol;Acc:HGNC:3061]	7.44	7.42	7.67	34.74	46.32	21.6	0.23	-2.12	0.02	0.25	down	yes
MSTRG.17115	.	MSTRG.17115.1	NA	NA	NA	NA	NA	1.37	0.78	0.99	0	0	0.26	2.2	1.14	0	0.15	up	yes
MSTRG.17122	TRIB3	ENST00000615226;ENST00000217233;ENST00000449710;ENST00000422053	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0004672(protein kinase activity);GO:0004860(protein kinase inhibitor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008286(insulin receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010827(regulation of glucose transport);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0031625(ubiquitin protein ligase binding);GO:0031965(nuclear membrane);GO:0032092(positive regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032869(cellular response to insulin stimulus);GO:0034976(response to endoplasmic reticulum stress);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043405(regulation of MAP kinase activity);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0045087(innate immune response);GO:0045599(negative regulation of fat cell differentiation);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0055106(ubiquitin-protein transferase regulator activity);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1903507(negative regulation of nucleic acid-templated transcription)"	NA	NA	NA	tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228]	222.82	168.69	155.55	1.61	5.53	6.11	53.67	5.75	0	0.14	up	yes
MSTRG.17123	TRIB3	MSTRG.17123.1	NA	NA	NA	NA	NA	2.43	2.43	2.03	0.04	0.07	0.38	3.07	1.62	0	0.17	up	yes
MSTRG.17124	RBCK1	ENST00000411647;ENST00000465226;ENST00000382214;ENST00000356286;ENST00000415942;ENST00000475269;ENST00000441733;ENST00000353660;ENST00000400245;ENST00000382181;ENST00000400247;ENST00000414880;ENST00000621487;ENST00000468272	GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0016032(viral process);GO:0016874(ligase activity);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043065(positive regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060546(negative regulation of necroptotic process);GO:0071797(LUBAC complex);GO:0097039(protein linear polyubiquitination);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)	NA	NA	NA	RanBP-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864]	42.4	35	35.31	8.71	9.8	10.62	4.03	2.01	0	0.08	up	yes
MSTRG.17127	CSNK2A1	MSTRG.17127.1;ENST00000619801;ENST00000400227;ENST00000217244;ENST00000349736;ENST00000619188;ENST00000400217;ENST00000460062;ENST00000609606;ENST00000608066;ENST00000609525;ENST00000608490	"GO:0000278(mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0008284(positive regulation of cell proliferation);GO:0016055(Wnt signaling pathway);GO:0016580(Sin3 complex);GO:0016581(NuRD complex);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030307(positive regulation of cell growth);GO:0031519(PcG protein complex);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045732(positive regulation of protein catabolic process);GO:0047485(protein N-terminus binding);GO:0048511(rhythmic process);GO:0051879(Hsp90 protein binding);GO:0061077(chaperone-mediated protein folding);GO:0071174(mitotic spindle checkpoint)"	03008(Ribosome biogenesis in eukaryotes);04310(Wnt signaling pathway);04520(Adherens junction);04530(Tight junction);05162(Measles)	NA	NA	"casein kinase 2, alpha 1 polypeptide [Source:HGNC Symbol;Acc:HGNC:2457]"	42.33	45.36	35.1	14.43	14.84	12.57	2.68	1.42	0	0.18	up	yes
MSTRG.17129	RP5-850E9.3	MSTRG.17129.1;ENST00000381962;ENST00000488788	NA	NA	NA	NA	Uncharacterized protein  [Source:UniProtKB/TrEMBL;Acc:S4R3F8]	44.72	60.8	42.3	16.82	20.64	12.1	2.51	1.33	0.03	0.28	up	yes
MSTRG.17152	ZNF343	ENST00000381342;ENST00000438552;ENST00000339610;ENST00000474384;ENST00000461548;MSTRG.17152.6;MSTRG.17152.7;MSTRG.17152.8;MSTRG.17152.9;ENST00000465019;MSTRG.17152.10;ENST00000278772;ENST00000617391;ENST00000612935;ENST00000445484;ENST00000381253;ENST00000421216	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 343 [Source:HGNC Symbol;Acc:HGNC:16017]	28.74	32.15	36.44	59.67	75.37	60.78	0.49	-1.03	0.02	0.25	down	yes
MSTRG.17154	NOP56	ENST00000329276;ENST00000494697;ENST00000470143;MSTRG.17154.4;ENST00000469588;MSTRG.17154.5;ENST00000445139;MSTRG.17154.8;ENST00000460258;ENST00000496775;ENST00000480992;ENST00000606420;ENST00000484998;ENST00000612233;ENST00000467196;ENST00000616692;ENST00000415272;ENST00000492135;ENST00000466447;ENST00000480447;ENST00000490753;ENST00000471023;ENST00000462630;ENST00000467857	GO:0000154(rRNA modification);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0016020(membrane);GO:0030515(snoRNA binding);GO:0031428(box C/D snoRNP complex);GO:0032040(small-subunit processome);GO:0044822(poly(A) RNA binding);GO:0070761(pre-snoRNP complex)	03008(Ribosome biogenesis in eukaryotes)	NA	NA	NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911]	9.49	10.11	12.08	48.42	57.61	37.42	0.22	-2.17	0	0.18	down	yes
MSTRG.1716	PDE4DIP	MSTRG.1716.1	NA	NA	NA	NA	NA	3.9	4.32	6.9	0.84	1.11	1.43	2.87	1.52	0.02	0.27	up	yes
MSTRG.17185	RNF24	MSTRG.17185.1;MSTRG.17185.2;ENST00000336095;ENST00000358395;ENST00000545616	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0016021(integral component of membrane)	NA	NA	NA	ring finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13779]	4.31	0.9	2.96	0.5	0.56	0.71	3.14	1.65	0.02	0.26	up	yes
MSTRG.17187	SMOX	ENST00000493223;MSTRG.17187.2;ENST00000621355;ENST00000278795;ENST00000305958;ENST00000339123;ENST00000484515;ENST00000346595;ENST00000379460;ENST00000457205;ENST00000494098;ENST00000486998;ENST00000466004	GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006595(polyamine metabolic process);GO:0006596(polyamine biosynthetic process);GO:0006598(polyamine catabolic process);GO:0006805(xenobiotic metabolic process);GO:0016491(oxidoreductase activity);GO:0034641(cellular nitrogen compound metabolic process);GO:0044281(small molecule metabolic process);GO:0046208(spermine catabolic process);GO:0046592(polyamine oxidase activity);GO:0052894(norspermine:oxygen oxidoreductase activity);GO:0052895(N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0055114(oxidation-reduction process)	NA	NA	NA	spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]	69.45	53.3	45.93	14.7	13.88	26.45	3.81	1.93	0.01	0.23	up	yes
MSTRG.17195	PCNA	ENST00000379143;ENST00000379160	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000701(purine-specific mismatch base pair DNA N-glycosylase activity);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005663(DNA replication factor C complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006272(leading strand elongation);GO:0006275(regulation of DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0019985(translesion synthesis);GO:0030331(estrogen receptor binding);GO:0030337(DNA polymerase processivity factor activity);GO:0030855(epithelial cell differentiation);GO:0030971(receptor tyrosine kinase binding);GO:0032077(positive regulation of deoxyribonuclease activity);GO:0032139(dinucleotide insertion or deletion binding);GO:0032201(telomere maintenance via semi-conservative replication);GO:0032405(MutLalpha complex binding);GO:0033993(response to lipid);GO:0034644(cellular response to UV);GO:0035035(histone acetyltransferase binding);GO:0042276(error-prone translesion synthesis);GO:0042769(DNA damage response, detection of DNA damage);GO:0042802(identical protein binding);GO:0043596(nuclear replication fork);GO:0043626(PCNA complex);GO:0045739(positive regulation of DNA repair);GO:0045740(positive regulation of DNA replication);GO:0046686(response to cadmium ion);GO:0070062(extracellular exosome);GO:0070182(DNA polymerase binding);GO:0070557(PCNA-p21 complex);GO:0070987(error-free translesion synthesis)"	03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);04110(Cell cycle)	NA	NA	proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729]	35.28	39.57	29.02	191.65	209.75	119.96	0.18	-2.46	0.01	0.2	down	yes
MSTRG.17198	GPCPD1	ENST00000379019;ENST00000418646;ENST00000481038;MSTRG.17198.6;MSTRG.17198.3;MSTRG.17198.2;MSTRG.17198.4;MSTRG.17198.5;MSTRG.17198.9;ENST00000462080;ENST00000633552;ENST00000473797;ENST00000481690	GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0007519(skeletal muscle tissue development);GO:0008081(phosphoric diester hydrolase activity);GO:0030246(carbohydrate binding);GO:0044281(small molecule metabolic process);GO:0046474(glycerophospholipid biosynthetic process);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:2001070(starch binding)	NA	NA	NA	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:26957]	10.53	9.57	8.97	3.54	2.23	1.59	2.83	1.5	0.02	0.25	up	yes
MSTRG.17203	MCM8	ENST00000378883;ENST00000378886;ENST00000378896;ENST00000610722;MSTRG.17203.5;ENST00000265187	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000724(double-strand break repair via homologous recombination);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006974(cellular response to DNA damage stimulus);GO:0007292(female gamete generation);GO:0048232(male gamete generation);GO:0097362(MCM8-MCM9 complex)	NA	NA	NA	minichromosome maintenance complex component 8 [Source:HGNC Symbol;Acc:HGNC:16147]	1.31	2.01	1.28	9.4	6.7	2.19	0.27	-1.88	0.04	0.33	down	yes
MSTRG.1727	HIST2H4A	ENST00000578186;ENST00000618193;MSTRG.1727.2;ENST00000614272;ENST00000613412	"GO:0000183(chromatin silencing at rDNA);GO:0000228(nuclear chromosome);GO:0000278(mitotic cell cycle);GO:0000723(telomere maintenance);GO:0000786(nucleosome);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006352(DNA-templated transcription, initiation);GO:0007264(small GTPase mediated signal transduction);GO:0010467(gene expression);GO:0016020(membrane);GO:0032776(DNA methylation on cytosine);GO:0034080(CENP-A containing nucleosome assembly);GO:0035574(histone H4-K20 demethylation);GO:0035575(histone demethylase activity (H4-K20 specific));GO:0040029(regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0043234(protein complex);GO:0044822(poly(A) RNA binding);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0046982(protein heterodimerization activity);GO:0051290(protein heterotetramerization);GO:0070062(extracellular exosome)"	NA	NA	NA	"histone cluster 2, H4a [Source:HGNC Symbol;Acc:HGNC:4794]"	3.35	1.92	4.82	0.65	1.11	1.68	2.54	1.34	0.04	0.31	up	yes
MSTRG.17272	SNRPB2	MSTRG.17272.2;MSTRG.17272.1;ENST00000377943;ENST00000246071;ENST00000478522	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0002230(positive regulation of defense response to virus by host);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005686(U2 snRNP);GO:0005730(nucleolus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0017069(snRNA binding);GO:0071013(catalytic step 2 spliceosome)"	03040(Spliceosome)	NA	NA	small nuclear ribonucleoprotein polypeptide B [Source:HGNC Symbol;Acc:HGNC:11155]	99.16	105.64	103.07	248.09	245.64	186.21	0.42	-1.25	0	0.18	down	yes
MSTRG.17284	MGME1	MSTRG.17284.1;MSTRG.17284.2;MSTRG.17284.3;ENST00000377710;ENST00000377709;ENST00000377704;ENST00000467391	GO:0000002(mitochondrial genome maintenance);GO:0005739(mitochondrion);GO:0006264(mitochondrial DNA replication);GO:0008297(single-stranded DNA exodeoxyribonuclease activity);GO:0043504(mitochondrial DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis)	NA	NA	NA	mitochondrial genome maintenance exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:16205]	4.2	7.01	8.84	20.86	20.53	12.94	0.3	-1.72	0.01	0.24	down	yes
MSTRG.17286	CSRP2BP	MSTRG.17286.2;MSTRG.17286.1;MSTRG.17286.3;ENST00000432901;ENST00000464792;ENST00000489422;ENST00000484001;ENST00000492286;ENST00000435364;ENST00000377681;ENST00000489634	GO:0000086(G2/M transition of mitotic cell cycle);GO:0004402(histone acetyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0008080(N-acetyltransferase activity);GO:0008152(metabolic process);GO:0016573(histone acetylation);GO:0030274(LIM domain binding);GO:0043966(histone H3 acetylation)	NA	NA	NA	CSRP2 binding protein [Source:HGNC Symbol;Acc:HGNC:15904]	3.6	5.38	6.74	10.13	9.6	9.2	0.5	-1.01	0.03	0.28	down	yes
MSTRG.17300	DTD1	ENST00000435844;ENST00000411646;ENST00000608034;ENST00000618693;ENST00000377452;ENST00000494921	"GO:0002161(aminoacyl-tRNA editing activity);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006399(tRNA metabolic process);GO:0006450(regulation of translational fidelity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0019478(D-amino acid catabolic process);GO:0046872(metal ion binding);GO:0051500(D-tyrosyl-tRNA(Tyr) deacylase activity)"	NA	NA	NA	D-tyrosyl-tRNA deacylase 1 [Source:HGNC Symbol;Acc:HGNC:16219]	65.74	62.84	59.95	22.14	24.2	36.91	2.61	1.38	0.01	0.24	up	yes
MSTRG.17336	NAPB	ENST00000398425;ENST00000432543;ENST00000617876;ENST00000377026;MSTRG.17336.6;MSTRG.17336.5;ENST00000472855;ENST00000468128;ENST00000487502	"GO:0005483(soluble NSF attachment protein activity);GO:0005515(protein binding);GO:0005774(vacuolar membrane);GO:0006886(intracellular protein transport);GO:0010807(regulation of synaptic vesicle priming);GO:0019905(syntaxin binding);GO:0031201(SNARE complex);GO:0035249(synaptic transmission, glutamatergic);GO:0035494(SNARE complex disassembly);GO:0043209(myelin sheath);GO:0061025(membrane fusion);GO:0070044(synaptobrevin 2-SNAP-25-syntaxin-1a complex);GO:0070062(extracellular exosome)"	NA	NA	NA	"N-ethylmaleimide-sensitive factor attachment protein, beta [Source:HGNC Symbol;Acc:HGNC:15751]"	5.34	5.47	4.32	1.93	2.11	1.91	2.02	1.02	0.01	0.19	up	yes
MSTRG.17341	CST7	ENST00000480798	GO:0004866(endopeptidase inhibitor activity);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0006955(immune response);GO:0010951(negative regulation of endopeptidase activity)	NA	NA	NA	cystatin F (leukocystatin) [Source:HGNC Symbol;Acc:HGNC:2479]	11.75	17.73	22.28	0.12	0.29	0.41	12.8	3.68	0	0.16	up	yes
MSTRG.17364	RP13-401N8.3	MSTRG.17364.1;ENST00000510553	NA	NA	NA	NA	NA	0.6	0.82	1.05	2.9	2.74	1.7	0.46	-1.11	0.01	0.24	down	yes
MSTRG.17398	TPX2	MSTRG.17398.1;ENST00000300403;ENST00000340513;MSTRG.17398.4	NA	NA	NA	NA	NA	23.54	22.88	10.76	198.23	230.66	69.45	0.11	-3.25	0.03	0.3	down	yes
MSTRG.17399	DUSP15	ENST00000447647;ENST00000278979;ENST00000398083;ENST00000486996;ENST00000398084;ENST00000375966;ENST00000339738;ENST00000459848;ENST00000493115;ENST00000428829	GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006470(protein dephosphorylation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042127(regulation of cell proliferation);GO:0046330(positive regulation of JNK cascade)	NA	NA	NA	dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236]	7.01	6.25	4.1	0.39	0.52	1.62	4.61	2.2	0.01	0.24	up	yes
MSTRG.17421	DNMT3B	ENST00000328111;ENST00000348286;ENST00000353855;ENST00000443239	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000792(heterochromatin);GO:0001666(response to hypoxia);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0003886(DNA (cytosine-5-)-methyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005720(nuclear heterochromatin);GO:0005737(cytoplasm);GO:0006306(DNA methylation);GO:0006346(methylation-dependent chromatin silencing);GO:0006349(regulation of gene expression by genetic imprinting);GO:0008168(methyltransferase activity);GO:0009008(DNA-methyltransferase activity);GO:0009636(response to toxic substance);GO:0010212(response to ionizing radiation);GO:0010424(DNA methylation on cytosine within a CG sequence);GO:0010467(gene expression);GO:0010628(positive regulation of gene expression);GO:0014823(response to activity);GO:0031000(response to caffeine);GO:0031503(protein complex localization);GO:0032355(response to estradiol);GO:0032776(DNA methylation on cytosine);GO:0033189(response to vitamin A);GO:0040029(regulation of gene expression, epigenetic);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0042826(histone deacetylase binding);GO:0043231(intracellular membrane-bounded organelle);GO:0045322(unmethylated CpG binding);GO:0045666(positive regulation of neuron differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046499(S-adenosylmethioninamine metabolic process);GO:0046872(metal ion binding);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0051573(negative regulation of histone H3-K9 methylation);GO:0051718(DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates);GO:0060821(inactivation of X chromosome by DNA methylation);GO:0071230(cellular response to amino acid stimulus);GO:0071455(cellular response to hyperoxia);GO:0071549(cellular response to dexamethasone stimulus)"	00270(Cysteine and methionine metabolism);01100(Metabolic pathways)	NA	NA	DNA (cytosine-5-)-methyltransferase 3 beta [Source:HGNC Symbol;Acc:HGNC:2979]	0.66	0.67	0.78	3.08	3.55	2.09	0.4	-1.31	0.01	0.23	down	yes
MSTRG.17433	E2F1	ENST00000343380	"GO:0000077(DNA damage checkpoint);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000278(mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0001047(core promoter binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0007219(Notch signaling pathway);GO:0007283(spermatogenesis);GO:0008134(transcription factor binding);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010628(positive regulation of gene expression);GO:0012501(programmed cell death);GO:0019901(protein kinase binding);GO:0030900(forebrain development);GO:0035189(Rb-E2F complex);GO:0043276(anoikis);GO:0043392(negative regulation of DNA binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045599(negative regulation of fat cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048146(positive regulation of fibroblast proliferation);GO:0048255(mRNA stabilization);GO:0051726(regulation of cell cycle);GO:0070345(negative regulation of fat cell proliferation);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071466(cellular response to xenobiotic stimulus);GO:0071930(negative regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1990086(lens fiber cell apoptotic process);GO:1990090(cellular response to nerve growth factor stimulus);GO:2000045(regulation of G1/S transition of mitotic cell cycle)"	04110(Cell cycle);05200(Pathways in cancer);05212(Pancreatic cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia);05222(Small cell lung cancer);05223(Non-small cell lung cancer)	NA	NA	E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113]	3.75	3.98	1.49	19.33	18.72	13.59	0.2	-2.31	0.02	0.26	down	yes
MSTRG.17434	PXMP4	ENST00000409299;ENST00000344022;ENST00000217398	GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0008150(biological_process);GO:0016021(integral component of membrane)	NA	NA	NA	"peroxisomal membrane protein 4, 24kDa [Source:HGNC Symbol;Acc:HGNC:15920]"	0.67	0.65	0.99	2.73	2.49	3.33	0.47	-1.08	0.01	0.22	down	yes
MSTRG.1745	LINC00869	MSTRG.1745.2;MSTRG.1745.1;MSTRG.1745.3;ENST00000611769;ENST00000619653;ENST00000612135;MSTRG.1745.7;ENST00000429388;MSTRG.1745.8;ENST00000622695;ENST00000620190;ENST00000610578;ENST00000621156;ENST00000439719;ENST00000435115;ENST00000430442;ENST00000622079;ENST00000610297	NA	NA	NA	NA	NA	3.04	2.9	2.84	0.7	1.18	1.4	2.11	1.07	0.01	0.2	up	yes
MSTRG.17510	AAR2	MSTRG.17510.1;MSTRG.17510.2;MSTRG.17510.3;MSTRG.17510.4;ENST00000320849;ENST00000373932	NA	NA	NA	NA	AAR2 splicing factor homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:15886]	6.22	7.74	9.59	17.36	17.87	15.47	0.44	-1.19	0.01	0.23	down	yes
MSTRG.17511	DLGAP4	ENST00000373913;ENST00000339266;ENST00000475894;MSTRG.17511.6;ENST00000482872;ENST00000495241;ENST00000491207;ENST00000482037;ENST00000340491;ENST00000479220;ENST00000489701;ENST00000479951;ENST00000478910;ENST00000497862;ENST00000477195	GO:0005515(protein binding);GO:0016020(membrane);GO:0023052(signaling);GO:0045202(synapse)	NA	NA	NA	"discs, large (Drosophila) homolog-associated protein 4 [Source:HGNC Symbol;Acc:HGNC:24476]"	27.03	22.77	17.26	7.63	7.74	7.28	2.86	1.51	0.01	0.22	up	yes
MSTRG.17521	DSN1	ENST00000426836;ENST00000373740;ENST00000448110;ENST00000473615;ENST00000480153;MSTRG.17521.2;ENST00000373750;ENST00000373734;MSTRG.17521.9;ENST00000438549;ENST00000447406	GO:0000278(mitotic cell cycle);GO:0000444(MIS12/MIND type complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0051301(cell division)	NA	NA	NA	"DSN1, MIS12 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16165]"	3.36	6.06	4.67	21.14	19.3	8.6	0.24	-2.07	0.01	0.23	down	yes
MSTRG.17522	SOGA1	ENST00000237536;MSTRG.17522.2;ENST00000279034;ENST00000465671;ENST00000463491	GO:0003674(molecular_function);GO:0005615(extracellular space);GO:0008286(insulin receptor signaling pathway);GO:0010506(regulation of autophagy);GO:0045721(negative regulation of gluconeogenesis);GO:0070062(extracellular exosome)	NA	NA	NA	"suppressor of glucose, autophagy associated 1 [Source:HGNC Symbol;Acc:HGNC:16111]"	3.39	4.92	5.71	16.21	18.81	14.9	0.28	-1.83	0	0.18	down	yes
MSTRG.17525	RBL1	MSTRG.17525.1;ENST00000373664;ENST00000344359;ENST00000527999	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007049(cell cycle);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008134(transcription factor binding);GO:0010467(gene expression);GO:0016032(viral process);GO:0016568(chromatin modification);GO:0043550(regulation of lipid kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051726(regulation of cell cycle)"	04110(Cell cycle);04350(TGF-beta signaling pathway)	NA	NA	retinoblastoma-like 1 [Source:HGNC Symbol;Acc:HGNC:9893]	0.6	1.39	1.04	5.29	5.28	1.28	0.3	-1.72	0.05	0.34	down	yes
MSTRG.17546	SNHG17	ENST00000422519;MSTRG.17546.2;MSTRG.17546.4;MSTRG.17546.6;MSTRG.17546.3;MSTRG.17546.5;MSTRG.17546.7;MSTRG.17546.8;MSTRG.17546.9;MSTRG.17546.10;MSTRG.17546.11;ENST00000423536;ENST00000436764;ENST00000449469;ENST00000414142;ENST00000417578;ENST00000413755;ENST00000456953;ENST00000424235	NA	NA	NA	NA	NA	15.43	12.27	12.15	4.13	4.34	5.18	2.91	1.54	0	0.11	up	yes
MSTRG.17578	MYBL2	ENST00000396863;MSTRG.17578.2;ENST00000217026	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0031523(Myb complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051726(regulation of cell cycle);GO:0090307(mitotic spindle assembly)	NA	NA	NA	v-myb avian myeloblastosis viral oncogene homolog-like 2 [Source:HGNC Symbol;Acc:HGNC:7548]	9.22	8.27	3.18	106.44	138.28	61.26	0.07	-3.81	0.02	0.25	down	yes
MSTRG.17580	TOX2	ENST00000341197;MSTRG.17580.2;MSTRG.17580.3;ENST00000423191;ENST00000372999;ENST00000358131;ENST00000413823	"GO:0001085(RNA polymerase II transcription factor binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008585(female gonad development);GO:0034698(response to gonadotropin);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	TOX high mobility group box family member 2 [Source:HGNC Symbol;Acc:HGNC:16095]	6.61	5.47	4.45	1.94	1.91	2.33	2.35	1.23	0.01	0.2	up	yes
MSTRG.17582	OSER1	MSTRG.17582.2;MSTRG.17582.1;ENST00000372970;ENST00000255174	GO:0070301(cellular response to hydrogen peroxide)	NA	NA	NA	oxidative stress responsive serine-rich 1 [Source:HGNC Symbol;Acc:HGNC:16105]	18.01	17.83	12.81	4.59	4.82	3.56	3.12	1.64	0.01	0.21	up	yes
MSTRG.17591	PABPC1L	MSTRG.17591.4;MSTRG.17591.5;MSTRG.17591.6;MSTRG.17591.1;MSTRG.17591.2;MSTRG.17591.3;ENST00000217074;ENST00000255136;ENST00000537323;ENST00000481196;ENST00000490798;ENST00000476056;ENST00000372824;ENST00000372819;ENST00000217075;ENST00000479873;ENST00000465761;ENST00000372826;ENST00000474208;ENST00000372822;ENST00000482486	GO:0000166(nucleotide binding);GO:0001556(oocyte maturation);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006378(mRNA polyadenylation);GO:0070062(extracellular exosome)	03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)	NA	NA	"poly(A) binding protein, cytoplasmic 1-like [Source:HGNC Symbol;Acc:HGNC:15797]"	6.95	5.07	7.13	1.35	1.42	1.82	3.31	1.73	0	0.14	up	yes
MSTRG.17597	SLPI	ENST00000338380	GO:0004866(endopeptidase inhibitor activity);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0019899(enzyme binding);GO:0030414(peptidase inhibitor activity);GO:0031012(extracellular matrix);GO:0032091(negative regulation of protein binding);GO:0045071(negative regulation of viral genome replication);GO:0070062(extracellular exosome)	NA	NA	NA	secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092]	1.43	2.92	4.7	0	0	0.2	3.09	1.63	0.04	0.33	up	yes
MSTRG.17600	SDC4	ENST00000372733	"GO:0001523(retinoid metabolic process);GO:0001657(ureteric bud development);GO:0001843(neural tube closure);GO:0001968(fibronectin binding);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005796(Golgi lumen);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0005975(carbohydrate metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0007603(phototransduction, visible light);GO:0009986(cell surface);GO:0010762(regulation of fibroblast migration);GO:0016477(cell migration);GO:0030198(extracellular matrix organization);GO:0030203(glycosaminoglycan metabolic process);GO:0030204(chondroitin sulfate metabolic process);GO:0042060(wound healing);GO:0043034(costamere);GO:0043202(lysosomal lumen);GO:0044281(small molecule metabolic process);GO:0045121(membrane raft);GO:0045860(positive regulation of protein kinase activity);GO:0051496(positive regulation of stress fiber assembly);GO:0051894(positive regulation of focal adhesion assembly);GO:0060122(inner ear receptor stereocilium organization);GO:0070053(thrombospondin receptor activity);GO:0070062(extracellular exosome);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly)"	04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));05144(Malaria)	NA	NA	syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661]	255.39	232.3	375.55	59.68	62.6	97.23	4.45	2.15	0.01	0.24	up	yes
MSTRG.17626	PLTP	ENST00000354050;ENST00000372420;ENST00000372431;ENST00000477313;ENST00000420868	GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006629(lipid metabolic process);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0010189(vitamin E biosynthetic process);GO:0010875(positive regulation of cholesterol efflux);GO:0030317(sperm motility);GO:0034375(high-density lipoprotein particle remodeling)	03320(PPAR signaling pathway)	NA	NA	phospholipid transfer protein [Source:HGNC Symbol;Acc:HGNC:9093]	19.45	18.48	16.1	3.54	3.41	10.33	3.93	1.97	0.04	0.32	up	yes
MSTRG.17628	.	MSTRG.17628.1	NA	NA	NA	NA	NA	0	0	0	1.26	1.79	1.81	0.41	-1.29	0	0.15	down	yes
MSTRG.17631	.	MSTRG.17631.1	NA	NA	NA	NA	NA	0.21	0.16	0.39	1.64	1.41	1.83	0.49	-1.04	0.01	0.2	down	yes
MSTRG.17632	NCOA5	ENST00000290231;MSTRG.17632.2;MSTRG.17632.3;MSTRG.17632.4;ENST00000372291	"GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0015629(actin cytoskeleton);GO:0042593(glucose homeostasis);GO:0044822(poly(A) RNA binding);GO:0046627(negative regulation of insulin receptor signaling pathway)"	NA	NA	NA	nuclear receptor coactivator 5 [Source:HGNC Symbol;Acc:HGNC:15909]	2.38	3.25	4.35	29.9	32.63	14.79	0.13	-2.93	0.01	0.21	down	yes
MSTRG.17642	ZMYND8	ENST00000311275;ENST00000536340;ENST00000360911;ENST00000355972;ENST00000396281;ENST00000446994;ENST00000611941;ENST00000619049;MSTRG.17642.1;MSTRG.17642.14;MSTRG.17642.11;MSTRG.17642.12;MSTRG.17642.13;MSTRG.17642.15;MSTRG.17642.16;MSTRG.17642.17;MSTRG.17642.18;ENST00000458360;ENST00000467200;ENST00000262975;ENST00000471951;ENST00000352431;ENST00000461685;ENST00000540497;ENST00000617418;ENST00000468376;ENST00000435836;ENST00000446894;ENST00000441977	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0070491(repressing transcription factor binding)	NA	NA	NA	"zinc finger, MYND-type containing 8 [Source:HGNC Symbol;Acc:HGNC:9397]"	1.4	2.21	3.35	10.86	8.19	8.99	0.26	-1.92	0.01	0.21	down	yes
MSTRG.17651	.	MSTRG.17651.1	NA	NA	NA	NA	NA	0.47	0.15	0.1	1.92	1.56	1.32	0.49	-1.03	0.02	0.27	down	yes
MSTRG.17662	ZFAS1	ENST00000371743;ENST00000417721;ENST00000441722;ENST00000450535;ENST00000458653;ENST00000326677;ENST00000428008;ENST00000620594;ENST00000623640;ENST00000615977;ENST00000618800	NA	NA	NA	NA	NA	436.51	496.53	369.09	38.31	54.2	51.65	9.36	3.23	0	0.14	up	yes
MSTRG.17685	ADNP	MSTRG.17685.1;ENST00000371602;MSTRG.17685.2;ENST00000621696;ENST00000349014;ENST00000396029;MSTRG.17685.7;ENST00000396032;ENST00000534467	"GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007614(short-term memory);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0010629(negative regulation of gene expression);GO:0010835(regulation of protein ADP-ribosylation);GO:0010976(positive regulation of neuron projection development);GO:0030424(axon);GO:0030425(dendrite);GO:0030828(positive regulation of cGMP biosynthetic process);GO:0031668(cellular response to extracellular stimulus);GO:0032091(negative regulation of protein binding);GO:0032147(activation of protein kinase activity);GO:0033484(nitric oxide homeostasis);GO:0042277(peptide binding);GO:0043025(neuronal cell body);GO:0043524(negative regulation of neuron apoptotic process);GO:0044849(estrous cycle);GO:0045773(positive regulation of axon extension);GO:0046872(metal ion binding);GO:0048487(beta-tubulin binding);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050805(negative regulation of synaptic transmission);GO:0051965(positive regulation of synapse assembly)"	NA	NA	NA	activity-dependent neuroprotector homeobox [Source:HGNC Symbol;Acc:HGNC:15766]	2.5	8.73	3.79	8.12	5.48	4.49	0.49	-1.02	0.02	0.26	down	yes
MSTRG.17693	NFATC2	MSTRG.17693.1;ENST00000371564;ENST00000396009;MSTRG.17693.2;MSTRG.17693.5;ENST00000609943;ENST00000610033;ENST00000414705;ENST00000609507;ENST00000496054	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001816(cytokine production);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006974(cellular response to DNA damage stimulus);GO:0008134(transcription factor binding);GO:0010628(positive regulation of gene expression);GO:0014904(myotube cell development);GO:0015629(actin cytoskeleton);GO:0016477(cell migration);GO:0030529(ribonucleoprotein complex);GO:0030890(positive regulation of B cell proliferation);GO:0033173(calcineurin-NFAT signaling cascade);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042493(response to drug);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044798(nuclear transcription factor complex);GO:0045087(innate immune response);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050853(B cell receptor signaling pathway);GO:1901741(positive regulation of myoblast fusion)"	04010(MAPK signaling pathway);04310(Wnt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04380(Osteoclast differentiation);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway)	NA	NA	"nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 [Source:HGNC Symbol;Acc:HGNC:7776]"	0.94	0.5	0.65	7.25	5.72	15.04	0.22	-2.17	0.02	0.26	down	yes
MSTRG.17706	AURKA	ENST00000395914;ENST00000371356;ENST00000347343;ENST00000395911;MSTRG.17706.6;MSTRG.17706.7;MSTRG.17706.2;MSTRG.17706.3;MSTRG.17706.4;MSTRG.17706.5;ENST00000312783;ENST00000395915;ENST00000395913;ENST00000395907;ENST00000441357;ENST00000420474;ENST00000422322;ENST00000456249;ENST00000451915	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0000212(meiotic spindle organization);GO:0000226(microtubule cytoskeleton organization);GO:0000278(mitotic cell cycle);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0006468(protein phosphorylation);GO:0007052(mitotic spindle organization);GO:0007057(spindle assembly involved in female meiosis I);GO:0007067(mitotic nuclear division);GO:0007100(mitotic centrosome separation);GO:0007126(meiotic nuclear division);GO:0009948(anterior/posterior axis specification);GO:0015630(microtubule cytoskeleton);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0019901(protein kinase binding);GO:0030496(midbody);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031616(spindle pole centrosome);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0032091(negative regulation of protein binding);GO:0032133(chromosome passenger complex);GO:0032355(response to estradiol);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032465(regulation of cytokinesis);GO:0035174(histone serine kinase activity);GO:0035404(histone-serine phosphorylation);GO:0042585(germinal vesicle);GO:0043066(negative regulation of apoptotic process);GO:0043146(spindle stabilization);GO:0043203(axon hillock);GO:0045120(pronucleus);GO:0045840(positive regulation of mitotic nuclear division);GO:0046605(regulation of centrosome cycle);GO:0046777(protein autophosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0051233(spindle midzone);GO:0051297(centrosome organization);GO:0051301(cell division);GO:0051642(centrosome localization);GO:0071539(protein localization to centrosome);GO:0072686(mitotic spindle);GO:0072687(meiotic spindle);GO:1900195(positive regulation of oocyte maturation);GO:1990138(neuron projection extension)"	04114(Oocyte meiosis)	NA	NA	aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393]	9.34	9.45	5.87	102.76	124.22	27.97	0.1	-3.39	0.03	0.3	down	yes
MSTRG.17711	TFAP2C	ENST00000201031;ENST00000416606;MSTRG.17711.2;MSTRG.17711.4	NA	NA	NA	NA	NA	16.83	19.59	35.49	64.32	54.61	66.23	0.35	-1.5	0.05	0.33	down	yes
MSTRG.17725	VAPB	ENST00000475243;MSTRG.17725.2;ENST00000395802;ENST00000520497;ENST00000265619;ENST00000463370;ENST00000476395	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006665(sphingolipid metabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0007029(endoplasmic reticulum organization);GO:0008017(microtubule binding);GO:0016021(integral component of membrane);GO:0019048(modulation by virus of host morphology or physiology);GO:0019899(enzyme binding);GO:0030148(sphingolipid biosynthetic process);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0033149(FFAT motif binding);GO:0042803(protein homodimerization activity);GO:0044281(small molecule metabolic process);GO:0044790(negative regulation by host of viral release from host cell);GO:0044791(positive regulation by host of viral release from host cell);GO:0044828(negative regulation by host of viral genome replication);GO:0044829(positive regulation by host of viral genome replication);GO:0045070(positive regulation of viral genome replication);GO:0046725(negative regulation by virus of viral protein levels in host cell);GO:0046982(protein heterodimerization activity);GO:0048487(beta-tubulin binding);GO:0090114(COPII-coated vesicle budding)	NA	NA	NA	VAMP (vesicle-associated membrane protein)-associated protein B and C [Source:HGNC Symbol;Acc:HGNC:12649]	3.01	3.44	5.55	8.82	8.1	8.95	0.48	-1.05	0.04	0.33	down	yes
MSTRG.17754	RP11-157P1.4	ENST00000414042	NA	NA	NA	NA	NA	2.99	1.17	0.89	0.33	0.64	0.71	2.19	1.13	0.03	0.29	up	yes
MSTRG.17768	SLCO4A1-AS1	MSTRG.17768.1;MSTRG.17768.2;MSTRG.17768.3;MSTRG.17768.4;MSTRG.17768.5;ENST00000451648;ENST00000411824;ENST00000433126	NA	NA	NA	NA	NA	5.77	3.19	9.55	0.88	0.73	0.44	4.29	2.1	0.03	0.3	up	yes
MSTRG.17788	EEF1A2	ENST00000298049;ENST00000217182	"GO:0003746(translation elongation factor activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0006414(translational elongation);GO:0008135(translation factor activity, RNA binding);GO:0010035(response to inorganic substance);GO:0019901(protein kinase binding);GO:0043025(neuronal cell body);GO:0043065(positive regulation of apoptotic process);GO:0043209(myelin sheath);GO:0090218(positive regulation of lipid kinase activity)"	03013(RNA transport)	NA	NA	eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:HGNC:3192]	25.45	21.58	22.58	3.37	2.45	7.39	5.85	2.55	0.01	0.24	up	yes
MSTRG.17789	PPDPF	ENST00000370179;ENST00000464438;MSTRG.17789.2;ENST00000370177;ENST00000473620	GO:0007275(multicellular organismal development);GO:0030154(cell differentiation)	NA	NA	NA	pancreatic progenitor cell differentiation and proliferation factor [Source:HGNC Symbol;Acc:HGNC:16142]	125.6	82.57	77.93	13.64	28.79	39.99	5.52	2.47	0.01	0.2	up	yes
MSTRG.1779	CIART	ENST00000447007;ENST00000369094;ENST00000369095;ENST00000417398;ENST00000290363;ENST00000469255;ENST00000497211	"GO:0001046(core promoter sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0016605(PML body);GO:0032922(circadian regulation of gene expression);GO:0045475(locomotor rhythm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070888(E-box binding)"	NA	NA	NA	circadian associated repressor of transcription [Source:HGNC Symbol;Acc:HGNC:25200]	23.92	14.52	7.18	2.53	2.55	3.05	4.98	2.31	0.03	0.29	up	yes
MSTRG.17792	CTD-3184A7.4	MSTRG.17792.1;MSTRG.17792.2;ENST00000449500;ENST00000411579	NA	NA	NA	NA	NA	10.51	7.68	5.47	1.81	2.61	3.08	3.09	1.63	0.01	0.23	up	yes
MSTRG.17793	STMN3	ENST00000540534;ENST00000370053;ENST00000631920;ENST00000632676;ENST00000634126	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0007019(microtubule depolymerization);GO:0007399(nervous system development);GO:0015631(tubulin binding);GO:0019904(protein domain specific binding);GO:0030424(axon);GO:0030426(growth cone);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0031122(cytoplasmic microtubule organization);GO:0031175(neuron projection development);GO:0035021(negative regulation of Rac protein signal transduction);GO:0043005(neuron projection);GO:0043087(regulation of GTPase activity);GO:0051493(regulation of cytoskeleton organization)	NA	NA	NA	stathmin-like 3 [Source:HGNC Symbol;Acc:HGNC:15926]	5.66	12.76	10.64	23.95	26.89	16.99	0.32	-1.65	0.01	0.22	down	yes
MSTRG.17794	TNFRSF6B	ENST00000318100;ENST00000370018;ENST00000508582;ENST00000469728;MSTRG.17794.5;ENST00000360203;ENST00000356810;ENST00000488316;ENST00000492259;ENST00000482936;ENST00000622743;ENST00000463361;ENST00000480273;ENST00000425905;ENST00000496281;ENST00000496816;ENST00000370003;ENST00000369996	GO:0004872(receptor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006915(apoptotic process);GO:0043066(negative regulation of apoptotic process)	04060(Cytokine-cytokine receptor interaction)	NA	NA	"tumor necrosis factor receptor superfamily, member 6b, decoy [Source:HGNC Symbol;Acc:HGNC:11921]"	1.13	0.86	1.17	4.06	4.47	3.63	0.42	-1.26	0	0.17	down	yes
MSTRG.17834	CH507-42P11.8	ENST00000613488;ENST00000624077	"GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0006468(protein phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0035556(intracellular signal transduction)"	NA	NA	NA	"Protein LOC102724428; SNF1-like kinase, isoform CRA_a  [Source:UniProtKB/TrEMBL;Acc:A0A0B4J2F2]"	4.45	4.31	6.24	0.64	0.65	0.78	3.57	1.84	0	0.17	up	yes
MSTRG.17838	CH507-152C13.1	ENST00000623375;ENST00000610664;ENST00000620065;ENST00000624739;ENST00000619610;MSTRG.17838.6	NA	NA	NA	NA	NA	4.91	5.75	7.12	13.85	16.83	11.36	0.42	-1.24	0.02	0.26	down	yes
MSTRG.17845	CH507-254M2.2	ENST00000617062;ENST00000625096;MSTRG.17845.3;ENST00000624461;ENST00000625115;MSTRG.17845.8;ENST00000610988	NA	NA	NA	NA	NA	0.42	0.61	0.05	3.35	1.33	1.18	0.38	-1.39	0.05	0.34	down	yes
MSTRG.17868	FP671120.6	MSTRG.17868.1	NA	NA	NA	NA	NA	203.45	95.08	278.84	4.19	3.22	50.62	36.12	5.17	0.04	0.31	up	yes
MSTRG.17914	USP25	MSTRG.17914.1;ENST00000285679;ENST00000351097;ENST00000285681;ENST00000400183;ENST00000547201;ENST00000464435;ENST00000478932	GO:0004197(cysteine-type endopeptidase activity);GO:0004843(ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006464(cellular protein modification process);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008233(peptidase activity);GO:0032183(SUMO binding);GO:0036459(ubiquitinyl hydrolase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0061136(regulation of proteasomal protein catabolic process);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination)	NA	NA	NA	ubiquitin specific peptidase 25 [Source:HGNC Symbol;Acc:HGNC:12624]	4.83	4.43	4.02	1.98	1.44	0.78	2.08	1.06	0.04	0.31	up	yes
MSTRG.1792	ENSA	ENST00000369016;MSTRG.1792.2;ENST00000369014;ENST00000361532;ENST00000361631;ENST00000509582;ENST00000339643;ENST00000271690;ENST00000356527;ENST00000513281;ENST00000505321;ENST00000503345;ENST00000354702;ENST00000503241;ENST00000362052	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0004864(protein phosphatase inhibitor activity);GO:0005102(receptor binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006810(transport);GO:0007067(mitotic nuclear division);GO:0007584(response to nutrient);GO:0008200(ion channel inhibitor activity);GO:0008601(protein phosphatase type 2A regulator activity);GO:0009749(response to glucose);GO:0019212(phosphatase inhibitor activity);GO:0019870(potassium channel inhibitor activity);GO:0034047(regulation of protein phosphatase type 2A activity);GO:0043086(negative regulation of catalytic activity);GO:0050796(regulation of insulin secretion);GO:0051301(cell division);GO:0051721(protein phosphatase 2A binding)	NA	NA	NA	endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]	11.04	10.93	13.05	36.68	27.58	26.53	0.37	-1.42	0.01	0.19	down	yes
MSTRG.17925	PPIAP22	ENST00000358455	NA	NA	NA	NA	NA	233.1	231.81	192.96	462.5	632.12	433.19	0.44	-1.18	0.02	0.27	down	yes
MSTRG.17957	BACH1	ENST00000447125;ENST00000420364;ENST00000548219;ENST00000547141;ENST00000550131;MSTRG.17957.5;ENST00000286800;ENST00000399921;MSTRG.17957.11;ENST00000548467;ENST00000451655;ENST00000435072;ENST00000422809;ENST00000468059;ENST00000462262	"GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000117(regulation of transcription involved in G2/M transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001205(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001206(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0020037(heme binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia)"	NA	NA	NA	"BTB and CNC homology 1, basic leucine zipper transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:935]"	5.72	7.68	6.78	1.78	1.99	1.08	2.56	1.35	0	0.19	up	yes
MSTRG.17978	TIAM1	ENST00000286827;MSTRG.17978.2;MSTRG.17978.3;ENST00000541036;MSTRG.17978.6;ENST00000491927;ENST00000469412;ENST00000455508	GO:0005057(receptor signaling protein activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0007160(cell-matrix adhesion);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007411(axon guidance);GO:0016477(cell migration);GO:0016601(Rac protein signal transduction);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0044291(cell-cell contact zone);GO:0046875(ephrin receptor binding);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0050772(positive regulation of axonogenesis);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0097190(apoptotic signaling pathway)	04062(Chemokine signaling pathway);04810(Regulation of actin cytoskeleton)	NA	NA	T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:HGNC:11805]	1.82	2.04	1.31	5.73	3.42	2.88	0.47	-1.09	0.04	0.32	down	yes
MSTRG.18057	MEMO1P1	ENST00000452572	NA	NA	NA	NA	NA	2.26	0.7	0.57	0	0	0	2.61	1.38	0.03	0.29	up	yes
MSTRG.18060	CBR3	ENST00000290354	GO:0000253(3-keto sterol reductase activity);GO:0004090(carbonyl reductase (NADPH) activity);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008152(metabolic process);GO:0016491(oxidoreductase activity);GO:0042376(phylloquinone catabolic process);GO:0050890(cognition);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding)	00590(Arachidonic acid metabolism);01100(Metabolic pathways)	NA	NA	carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549]	3.44	3.25	3.12	16.25	15.73	12.78	0.26	-1.95	0	0.13	down	yes
MSTRG.18095	WRB	ENST00000333781;MSTRG.18095.2;ENST00000623703;ENST00000487869;ENST00000471468;ENST00000398753;ENST00000442773;ENST00000380713;ENST00000380708;ENST00000466787;ENST00000415847;ENST00000490860;ENST00000478273;ENST00000476914;ENST00000480690	GO:0005634(nucleus);GO:0005789(endoplasmic reticulum membrane);GO:0016021(integral component of membrane);GO:0071816(tail-anchored membrane protein insertion into ER membrane)	NA	NA	NA	tryptophan rich basic protein [Source:HGNC Symbol;Acc:HGNC:12790]	1.56	3.55	3.07	6.16	5.27	4.7	0.44	-1.19	0	0.17	down	yes
MSTRG.18097	SH3BGR	ENST00000380637;ENST00000380634;ENST00000458295;ENST00000440288;ENST00000380631;ENST00000333634;ENST00000452550;MSTRG.18097.8;ENST00000423596;ENST00000447939	GO:0005070(SH3/SH2 adaptor activity);GO:0005829(cytosol);GO:0006461(protein complex assembly);GO:0009967(positive regulation of signal transduction);GO:0017124(SH3 domain binding)	NA	NA	NA	SH3 domain binding glutamate-rich protein [Source:HGNC Symbol;Acc:HGNC:10822]	11.44	16.58	20.97	0.84	1.45	1.05	7.34	2.88	0	0.18	up	yes
MSTRG.18116	U2AF1	ENST00000471250;ENST00000478282;ENST00000459639;ENST00000464750;ENST00000475639;ENST00000380276;ENST00000291552;MSTRG.18116.2;ENST00000398137;MSTRG.18116.10;ENST00000486519;ENST00000463599;ENST00000496462	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006397(mRNA processing);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0015030(Cajal body);GO:0016607(nuclear speck);GO:0031124(mRNA 3'-end processing);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0071013(catalytic step 2 spliceosome);GO:1903146(regulation of mitochondrion degradation);GO:1903955(positive regulation of protein targeting to mitochondrion)"	03040(Spliceosome);05131(Shigellosis)	NA	NA	U2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNC:12453]	3.23	3.45	4.11	7.77	9.37	6.24	0.5	-1.01	0.02	0.27	down	yes
MSTRG.18119	SIK1	ENST00000270162;MSTRG.18119.2;ENST00000478426	"GO:0000287(magnesium ion binding);GO:0002028(regulation of sodium ion transport);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007346(regulation of mitotic cell cycle);GO:0008140(cAMP response element binding protein binding);GO:0010830(regulation of myotube differentiation);GO:0010868(negative regulation of triglyceride biosynthetic process);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0019901(protein kinase binding);GO:0032792(negative regulation of CREB transcription factor activity);GO:0035556(intracellular signal transduction);GO:0043153(entrainment of circadian clock by photoperiod);GO:0045595(regulation of cell differentiation);GO:0045721(negative regulation of gluconeogenesis);GO:0046777(protein autophosphorylation);GO:0048511(rhythmic process);GO:0055007(cardiac muscle cell differentiation);GO:0071889(14-3-3 protein binding);GO:2000210(positive regulation of anoikis)"	NA	NA	NA	salt-inducible kinase 1 [Source:HGNC Symbol;Acc:HGNC:11142]	6.47	6.22	9.98	1.08	1.02	1.22	4.04	2.01	0.01	0.19	up	yes
MSTRG.18125	CSTB	ENST00000291568;ENST00000480147	GO:0002020(protease binding);GO:0004866(endopeptidase inhibitor activity);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008344(adult locomotory behavior);GO:0010466(negative regulation of peptidase activity);GO:0010951(negative regulation of endopeptidase activity);GO:0044822(poly(A) RNA binding);GO:0045861(negative regulation of proteolysis);GO:0070062(extracellular exosome)	NA	NA	NA	cystatin B (stefin B) [Source:HGNC Symbol;Acc:HGNC:2482]	41.53	34.88	30.66	17.74	20.7	13.26	2.05	1.03	0.05	0.33	up	yes
MSTRG.18133	PWP2	ENST00000291576;ENST00000456705;ENST00000486126;ENST00000471490;ENST00000476948	"GO:0000028(ribosomal small subunit assembly);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0030515(snoRNA binding);GO:0032040(small-subunit processome);GO:0034388(Pwp2p-containing subcomplex of 90S preribosome);GO:0044822(poly(A) RNA binding)"	03008(Ribosome biogenesis in eukaryotes)	NA	NA	PWP2 periodic tryptophan protein homolog (yeast) [Source:HGNC Symbol;Acc:HGNC:9711]	1.41	1.78	2.77	4.57	5.2	5.63	0.47	-1.08	0.03	0.3	down	yes
MSTRG.18159	POFUT2	MSTRG.18159.1;MSTRG.18159.2;ENST00000471540;ENST00000331343;ENST00000334538;ENST00000349485;ENST00000612472;ENST00000485190;ENST00000460932;ENST00000463917;ENST00000451615;ENST00000493524;ENST00000493811;ENST00000476653	"GO:0001707(mesoderm formation);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006004(fucose metabolic process);GO:0006493(protein O-linked glycosylation);GO:0008152(metabolic process);GO:0008417(fucosyltransferase activity);GO:0010468(regulation of gene expression);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016757(transferase activity, transferring glycosyl groups);GO:0036065(fucosylation);GO:0036066(protein O-linked fucosylation);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046922(peptide-O-fucosyltransferase activity);GO:0051046(regulation of secretion)"	00514(Other types of O-glycan biosynthesis)	NA	NA	protein O-fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:14683]	5.69	6.38	4.81	1.64	1.51	2.06	2.44	1.28	0.01	0.2	up	yes
MSTRG.18178	COL6A2	ENST00000300527;ENST00000310645;MSTRG.18178.3;ENST00000436769;ENST00000409416;ENST00000397763;ENST00000460886;ENST00000485591;ENST00000413758	GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007155(cell adhesion);GO:0007411(axon guidance);GO:0009749(response to glucose);GO:0022617(extracellular matrix disassembly);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0042383(sarcolemma);GO:0043234(protein complex);GO:0070062(extracellular exosome);GO:0070208(protein heterotrimerization);GO:1903561(extracellular vesicle)	04510(Focal adhesion);04512(ECM-receptor interaction);04974(Protein digestion and absorption)	NA	NA	"collagen, type VI, alpha 2 [Source:HGNC Symbol;Acc:HGNC:2212]"	192.84	158.16	168.82	49.28	58.35	63.79	3.44	1.78	0	0.08	up	yes
MSTRG.18186	MCM3AP	MSTRG.18186.1;MSTRG.18186.2;ENST00000291688;MSTRG.18186.4;ENST00000467026;ENST00000496607;ENST00000486937;ENST00000397708;MSTRG.18186.9;ENST00000481113;ENST00000447037;ENST00000430259;ENST00000494755;ENST00000479557;ENST00000426537	"GO:0002376(immune system process);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006606(protein import into nucleus);GO:0016746(transferase activity, transferring acyl groups);GO:0031965(nuclear membrane);GO:0051028(mRNA transport)"	NA	NA	NA	minichromosome maintenance complex component 3 associated protein [Source:HGNC Symbol;Acc:HGNC:6946]	3.29	4.09	5.84	8.69	9.75	8.89	0.49	-1.02	0.04	0.3	down	yes
MSTRG.18189	C21orf58	MSTRG.18189.1;ENST00000397683;MSTRG.18189.5;ENST00000291691;ENST00000397682;ENST00000397679;ENST00000397680;MSTRG.18189.10;ENST00000472607;ENST00000445935;ENST00000475776	NA	NA	NA	NA	chromosome 21 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:1300]	0.08	0.15	0.25	3.64	3.57	1.98	0.25	-1.97	0	0.18	down	yes
MSTRG.18190	PCNT	ENST00000359568;ENST00000490468;ENST00000480896;ENST00000466474;ENST00000483844;MSTRG.18190.6;ENST00000482575;ENST00000418394;ENST00000465356	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000226(microtubule cytoskeleton organization);GO:0000242(pericentriolar material);GO:0000278(mitotic cell cycle);GO:0001701(in utero embryonic development);GO:0001764(neuron migration);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005737(cytoplasm);GO:0005801(cis-Golgi network);GO:0005813(centrosome);GO:0005814(centriole);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005874(microtubule);GO:0006996(organelle organization);GO:0007051(spindle organization);GO:0016020(membrane);GO:0021696(cerebellar cortex morphogenesis);GO:0021772(olfactory bulb development);GO:0031514(motile cilium);GO:0034451(centriolar satellite);GO:0035108(limb morphogenesis);GO:0035264(multicellular organism growth);GO:0036064(ciliary basal body);GO:0042384(cilium assembly);GO:0043066(negative regulation of apoptotic process);GO:0045171(intercellular bridge);GO:0048854(brain morphogenesis);GO:0061351(neural precursor cell proliferation);GO:0090316(positive regulation of intracellular protein transport)	NA	NA	NA	pericentrin [Source:HGNC Symbol;Acc:HGNC:16068]	1.32	1.52	1.72	6.34	6.19	3.07	0.35	-1.5	0.02	0.27	down	yes
MSTRG.18265	CDC45	MSTRG.18265.1;ENST00000407835;ENST00000438587;ENST00000455750;ENST00000491520;ENST00000263201;ENST00000437685;ENST00000483431;ENST00000404724;ENST00000487669;ENST00000428937;ENST00000471470;ENST00000493724	GO:0000076(DNA replication checkpoint);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000727(double-strand break repair via break-induced replication);GO:0003682(chromatin binding);GO:0003688(DNA replication origin binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005656(nuclear pre-replicative complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006260(DNA replication);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0031261(DNA replication preinitiation complex);GO:0031298(replication fork protection complex);GO:0031938(regulation of chromatin silencing at telomere);GO:0032508(DNA duplex unwinding);GO:0043138(3'-5' DNA helicase activity);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1902977(mitotic DNA replication preinitiation complex assembly)	04110(Cell cycle)	NA	NA	cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739]	0.67	0.91	0.78	23.07	23.14	12.88	0.07	-3.74	0	0.14	down	yes
MSTRG.18282	RTN4R	ENST00000043402;ENST00000425986	GO:0004872(receptor activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0007409(axonogenesis);GO:0009986(cell surface);GO:0030426(growth cone);GO:0031225(anchored component of membrane);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0050771(negative regulation of axonogenesis);GO:0070062(extracellular exosome)	NA	NA	NA	reticulon 4 receptor [Source:HGNC Symbol;Acc:HGNC:18601]	2.05	1.18	1.34	0.15	0.1	0.04	2.98	1.57	0	0.19	up	yes
MSTRG.18287	RANBP1	ENST00000432879;ENST00000435265;ENST00000430524;ENST00000402752;ENST00000488484;ENST00000331821;ENST00000411892;ENST00000467920;ENST00000416427;ENST00000421656;ENST00000423859;ENST00000418705;ENST00000448394;ENST00000486575	GO:0005092(GDP-dissociation inhibitor activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0007051(spindle organization);GO:0007165(signal transduction);GO:0008536(Ran GTPase binding);GO:0010976(positive regulation of neuron projection development);GO:0016032(viral process);GO:0032838(cell projection cytoplasm);GO:0035690(cellular response to drug);GO:0043547(positive regulation of GTPase activity);GO:0046604(positive regulation of mitotic centrosome separation);GO:0046907(intracellular transport);GO:0050790(regulation of catalytic activity);GO:0051592(response to calcium ion);GO:0072750(cellular response to leptomycin B)	NA	NA	NA	RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847]	15.66	14.88	15.87	51.26	64.96	36.22	0.31	-1.69	0.02	0.25	down	yes
MSTRG.18335	PPIL2	ENST00000498589;ENST00000385018;MSTRG.18335.3;MSTRG.18335.4;ENST00000496819;ENST00000335025;MSTRG.18335.7;ENST00000398831;ENST00000626352;ENST00000458567;ENST00000417788;ENST00000484439;ENST00000406385;ENST00000498109;ENST00000485930;ENST00000446951;ENST00000462188	GO:0000209(protein polyubiquitination);GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005796(Golgi lumen);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0007596(blood coagulation);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0050900(leukocyte migration);GO:0061630(ubiquitin protein ligase activity);GO:0072659(protein localization to plasma membrane)	04120(Ubiquitin mediated proteolysis)	NA	NA	peptidylprolyl isomerase (cyclophilin)-like 2 [Source:HGNC Symbol;Acc:HGNC:9261]	2.15	2.16	3.74	7.35	7.4	5.66	0.43	-1.2	0.03	0.29	down	yes
MSTRG.18351	RAB36	ENST00000263116;ENST00000341989;MSTRG.18351.3;ENST00000420895	GO:0000139(Golgi membrane);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005794(Golgi apparatus);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0032482(Rab protein signal transduction)	NA	NA	NA	"RAB36, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9775]"	0.19	0.21	0.45	2.13	3.28	2.15	0.37	-1.44	0.01	0.23	down	yes
MSTRG.1836	TUFT1	ENST00000368849;ENST00000392712;ENST00000368848;MSTRG.1836.4;ENST00000353024;ENST00000498606;ENST00000461859;ENST00000490156	GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0030282(bone mineralization);GO:0030345(structural constituent of tooth enamel);GO:0042476(odontogenesis)	NA	NA	NA	tuftelin 1 [Source:HGNC Symbol;Acc:HGNC:12422]	19.08	16.41	10.67	5.5	6.36	4.83	2.56	1.36	0.03	0.3	up	yes
MSTRG.18365	CHCHD10	ENST00000520222;ENST00000401675;ENST00000484558;ENST00000523865;ENST00000517886	GO:0003674(molecular_function);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:0007005(mitochondrion organization);GO:2000984(negative regulation of ATP citrate synthase activity)	NA	NA	NA	coiled-coil-helix-coiled-coil-helix domain containing 10 [Source:HGNC Symbol;Acc:HGNC:15559]	5.09	4.42	3.46	0.96	1.16	2.66	2.58	1.37	0.03	0.29	up	yes
MSTRG.18368	SMARCB1	ENST00000417137;ENST00000344921;ENST00000263121;ENST00000407422;ENST00000407082;ENST00000491967;ENST00000477836	"GO:0000228(nuclear chromosome);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001741(XY body);GO:0001824(blastocyst development);GO:0001835(blastocyst hatching);GO:0002039(p53 binding);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006281(DNA repair);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007399(nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0015074(DNA integration);GO:0016514(SWI/SNF complex);GO:0030154(cell differentiation);GO:0030957(Tat protein binding);GO:0031492(nucleosomal DNA binding);GO:0039692(single stranded viral RNA replication via double stranded DNA intermediate);GO:0043044(ATP-dependent chromatin remodeling);GO:0043234(protein complex);GO:0043923(positive regulation by host of viral transcription);GO:0044772(mitotic cell cycle phase transition);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0090544(BAF-type complex)"	NA	NA	NA	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [Source:HGNC Symbol;Acc:HGNC:11103]"	23.96	23.67	29.52	58.1	63.15	44.79	0.45	-1.15	0.02	0.25	down	yes
MSTRG.1841	SNX27	ENST00000368841;ENST00000458013;ENST00000368843;ENST00000368838;ENST00000482791	"GO:0001770(establishment of natural killer cell polarity);GO:0001772(immunological synapse);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0007165(signal transduction);GO:0016197(endosomal transport);GO:0030904(retromer complex);GO:0031901(early endosome membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0035091(phosphatidylinositol binding);GO:0042493(response to drug);GO:0071203(WASH complex);GO:1990126(retrograde transport, endosome to plasma membrane)"	NA	NA	NA	sorting nexin family member 27 [Source:HGNC Symbol;Acc:HGNC:20073]	8.58	10.98	8.3	1.74	2.12	4.83	3.11	1.63	0.04	0.33	up	yes
MSTRG.18433	XBP1	ENST00000216037;ENST00000403532;ENST00000484256;ENST00000611155;ENST00000405219;ENST00000344347;ENST00000482720	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0001047(core promoter binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0001525(angiogenesis);GO:0001889(liver development);GO:0001934(positive regulation of protein phosphorylation);GO:0001935(endothelial cell proliferation);GO:0002020(protease binding);GO:0002070(epithelial cell maturation);GO:0002639(positive regulation of immunoglobulin production);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0006955(immune response);GO:0006990(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response);GO:0006996(organelle organization);GO:0007517(muscle organ development);GO:0010506(regulation of autophagy);GO:0010508(positive regulation of autophagy);GO:0010832(negative regulation of myotube differentiation);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0016049(cell growth);GO:0019901(protein kinase binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030331(estrogen receptor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031017(exocrine pancreas development);GO:0031062(positive regulation of histone methylation);GO:0031490(chromatin DNA binding);GO:0031625(ubiquitin protein ligase binding);GO:0031647(regulation of protein stability);GO:0031648(protein destabilization);GO:0031670(cellular response to nutrient);GO:0032008(positive regulation of TOR signaling);GO:0032869(cellular response to insulin stimulus);GO:0034599(cellular response to oxidative stress);GO:0034976(response to endoplasmic reticulum stress);GO:0035356(cellular triglyceride homeostasis);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0036498(IRE1-mediated unfolded protein response);GO:0036500(ATF6-mediated unfolded protein response);GO:0042149(cellular response to glucose starvation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0042632(cholesterol homeostasis);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0043066(negative regulation of apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0045348(positive regulation of MHC class II biosynthetic process);GO:0045579(positive regulation of B cell differentiation);GO:0045582(positive regulation of T cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048666(neuron development);GO:0051024(positive regulation of immunoglobulin secretion);GO:0051602(response to electrical stimulus);GO:0055089(fatty acid homeostasis);GO:0055092(sterol homeostasis);GO:0060096(serotonin secretion, neurotransmission);GO:0060612(adipose tissue development);GO:0060691(epithelial cell maturation involved in salivary gland development);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071222(cellular response to lipopolysaccharide);GO:0071230(cellular response to amino acid stimulus);GO:0071236(cellular response to antibiotic);GO:0071332(cellular response to fructose stimulus);GO:0071333(cellular response to glucose stimulus);GO:0071353(cellular response to interleukin-4);GO:0071375(cellular response to peptide hormone stimulus);GO:0071498(cellular response to fluid shear stress);GO:0071499(cellular response to laminar fluid shear stress);GO:1900100(positive regulation of plasma cell differentiation);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response);GO:1900103(positive regulation of endoplasmic reticulum unfolded protein response);GO:1900413(positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1901985(positive regulation of protein acetylation);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:1903489(positive regulation of lactation);GO:1990418(response to insulin-like growth factor stimulus);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:2000347(positive regulation of hepatocyte proliferation);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2000778(positive regulation of interleukin-6 secretion)"	04141(Protein processing in endoplasmic reticulum)	NA	NA	X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801]	36.11	36.48	38.95	8.3	6.85	8	4.29	2.1	0	0.1	up	yes
MSTRG.18449	EWSR1	ENST00000444626;ENST00000332050;ENST00000629659;ENST00000397938;ENST00000436425;ENST00000447973;ENST00000485037;ENST00000406548;ENST00000437155;ENST00000415761;ENST00000331029;ENST00000483415;ENST00000414183;ENST00000333395;ENST00000455726;ENST00000332035;ENST00000493426;ENST00000479135;ENST00000469669;ENST00000483629;ENST00000360091;ENST00000610553	"GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0042802(identical protein binding);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	EWS RNA-binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3508]	10.99	9.64	9.95	34.68	31.79	24.87	0.35	-1.53	0.01	0.19	down	yes
MSTRG.1849	RP11-98D18.9	ENST00000533481;ENST00000389897	NA	NA	NA	NA	NA	1.41	2.67	1.12	0.22	0.08	0.01	2.01	1.01	0.03	0.29	up	yes
MSTRG.18501	SMTN	ENST00000623789;ENST00000432777;ENST00000422839;ENST00000426927;ENST00000482444;ENST00000440425;ENST00000497697;ENST00000358743;ENST00000333137;ENST00000347557;ENST00000489337;ENST00000438223;ENST00000619644;ENST00000612341;ENST00000416786;ENST00000431481;ENST00000460658;ENST00000466272;ENST00000455608;ENST00000404574;ENST00000493335;ENST00000624247;ENST00000504335	GO:0003779(actin binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006939(smooth muscle contraction);GO:0007517(muscle organ development);GO:0008307(structural constituent of muscle);GO:0015629(actin cytoskeleton)	NA	NA	NA	smoothelin [Source:HGNC Symbol;Acc:HGNC:11126]	0.76	0.89	1.13	2.6	3.43	1.94	0.5	-1	0.03	0.29	down	yes
MSTRG.18503	SELM	ENST00000402395;ENST00000490967;ENST00000400299;ENST00000611680;ENST00000465536;ENST00000491958;ENST00000495533;ENST00000460642;ENST00000469262;ENST00000465447	GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0010269(response to selenium ion);GO:0035264(multicellular organism growth);GO:0035934(corticosterone secretion);GO:0042445(hormone metabolic process);GO:0060612(adipose tissue development)	NA	NA	NA	selenoprotein M [Source:EntrezGene;Acc:140606]	15.33	6.51	7.55	2.38	4.8	5.56	3.18	1.67	0	0.15	up	yes
MSTRG.18516	LINC01521	MSTRG.18516.1;ENST00000504184	NA	NA	NA	NA	NA	0.14	0.2	0.25	1.8	1.88	2.78	0.4	-1.31	0.01	0.2	down	yes
MSTRG.1854	THEM4	MSTRG.1854.1;MSTRG.1854.2;ENST00000368814;ENST00000471464;ENST00000483207;ENST00000477437;ENST00000489410	GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008286(insulin receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0032587(ruffle membrane);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0043491(protein kinase B signaling);GO:0045087(innate immune response);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:1902108(regulation of mitochondrial membrane permeability involved in apoptotic process)	NA	NA	NA	thioesterase superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:17947]	0.76	0.81	0.91	4.81	3.28	2.29	0.36	-1.48	0.01	0.23	down	yes
MSTRG.18560	HMOX1	ENST00000412893;ENST00000216117;ENST00000481190;ENST00000494998	GO:0001525(angiogenesis);GO:0001666(response to hypoxia);GO:0001935(endothelial cell proliferation);GO:0002246(wound healing involved in inflammatory response);GO:0002686(negative regulation of leukocyte migration);GO:0004392(heme oxygenase (decyclizing) activity);GO:0004630(phospholipase D activity);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005901(caveola);GO:0006778(porphyrin-containing compound metabolic process);GO:0006788(heme oxidation);GO:0006879(cellular iron ion homeostasis);GO:0006979(response to oxidative stress);GO:0007264(small GTPase mediated signal transduction);GO:0007588(excretion);GO:0008217(regulation of blood pressure);GO:0008219(cell death);GO:0008285(negative regulation of cell proliferation);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010656(negative regulation of muscle cell apoptotic process);GO:0014806(smooth muscle hyperplasia);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0019899(enzyme binding);GO:0020037(heme binding);GO:0031670(cellular response to nutrient);GO:0032764(negative regulation of mast cell cytokine production);GO:0034101(erythrocyte homeostasis);GO:0034383(low-density lipoprotein particle clearance);GO:0034395(regulation of transcription from RNA polymerase II promoter in response to iron);GO:0034605(cellular response to heat);GO:0035094(response to nicotine);GO:0035556(intracellular signal transduction);GO:0042167(heme catabolic process);GO:0042168(heme metabolic process);GO:0042542(response to hydrogen peroxide);GO:0042803(protein homodimerization activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043305(negative regulation of mast cell degranulation);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0043619(regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0043627(response to estrogen);GO:0044281(small molecule metabolic process);GO:0045080(positive regulation of chemokine biosynthetic process);GO:0045765(regulation of angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0045909(positive regulation of vasodilation);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0051260(protein homooligomerization);GO:0055072(iron ion homeostasis);GO:0055085(transmembrane transport);GO:0055114(oxidation-reduction process);GO:0071243(cellular response to arsenic-containing substance);GO:0071276(cellular response to cadmium ion);GO:0071456(cellular response to hypoxia);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)	00860(Porphyrin and chlorophyll metabolism);04978(Mineral absorption)	NA	NA	heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:5013]	12.01	7.69	7.63	4.39	4.22	4.45	2.15	1.1	0.01	0.23	up	yes
MSTRG.18561	MCM5	ENST00000216122;MSTRG.18561.2;ENST00000451351;ENST00000382011;ENST00000417343;ENST00000416905;ENST00000444778;ENST00000464908;ENST00000493076;ENST00000493569;ENST00000465557	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003682(chromatin binding);GO:0003688(DNA replication origin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0016020(membrane);GO:0032508(DNA duplex unwinding);GO:0042555(MCM complex);GO:0051301(cell division)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948]	2.88	2.92	3.19	21.95	20.15	15.22	0.18	-2.45	0	0.13	down	yes
MSTRG.18562	APOL6	MSTRG.18562.1;ENST00000409652	GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0042157(lipoprotein metabolic process)	NA	NA	NA	"apolipoprotein L, 6 [Source:HGNC Symbol;Acc:HGNC:14870]"	11.41	12.42	18.41	2.45	1.7	1.36	4.57	2.19	0.01	0.19	up	yes
MSTRG.18569	APOL1	ENST00000397278;ENST00000422706;ENST00000426053;ENST00000319136;MSTRG.18569.5;ENST00000422471;ENST00000475519;ENST00000438034;ENST00000427990;ENST00000431184	GO:0005254(chloride channel activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006821(chloride transport);GO:0006869(lipid transport);GO:0006898(receptor-mediated endocytosis);GO:0008203(cholesterol metabolic process);GO:0008289(lipid binding);GO:0019835(cytolysis);GO:0031224(intrinsic component of membrane);GO:0031640(killing of cells of other organism);GO:0034361(very-low-density lipoprotein particle);GO:0034364(high-density lipoprotein particle);GO:0042157(lipoprotein metabolic process);GO:0045087(innate immune response);GO:0072562(blood microparticle);GO:1902476(chloride transmembrane transport)	05143(African trypanosomiasis)	NA	NA	"apolipoprotein L, 1 [Source:HGNC Symbol;Acc:HGNC:618]"	2.5	2.62	5.14	0.42	0.4	0.99	2.83	1.5	0.04	0.33	up	yes
MSTRG.18574	FOXRED2	MSTRG.18574.1;ENST00000397224;MSTRG.18574.3;ENST00000216187;ENST00000366463;ENST00000397223	GO:0001948(glycoprotein binding);GO:0004497(monooxygenase activity);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)	NA	NA	NA	FAD-dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264]	2.5	3.12	5.21	14.55	12.56	8.05	0.29	-1.77	0.02	0.27	down	yes
MSTRG.1858	SPRR2D	MSTRG.1858.1;ENST00000360379;ENST00000368758;ENST00000368757;ENST00000368756	GO:0001533(cornified envelope);GO:0005737(cytoplasm);GO:0008544(epidermis development);GO:0031424(keratinization)	NA	NA	NA	small proline-rich protein 2D [Source:HGNC Symbol;Acc:HGNC:11264]	81.84	9.31	17.97	0.13	0.26	0.15	45.04	5.49	0.01	0.19	up	yes
MSTRG.18600	H1F0	ENST00000340857	GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005719(nuclear euchromatin);GO:0005794(Golgi apparatus);GO:0006309(apoptotic DNA fragmentation);GO:0006334(nucleosome assembly);GO:0006915(apoptotic process);GO:0006921(cellular component disassembly involved in execution phase of apoptosis);GO:0012501(programmed cell death);GO:0015629(actin cytoskeleton);GO:0031490(chromatin DNA binding);GO:0044822(poly(A) RNA binding)	NA	NA	NA	"H1 histone family, member 0 [Source:HGNC Symbol;Acc:HGNC:4714]"	196.88	141.42	170.39	82.76	86.81	76.41	2.24	1.17	0.01	0.19	up	yes
MSTRG.18620	KDELR3	ENST00000216014;ENST00000409006;ENST00000471268	GO:0005789(endoplasmic reticulum membrane);GO:0006621(protein retention in ER lumen);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response);GO:0044267(cellular protein metabolic process);GO:0046923(ER retention sequence binding)	05110(Vibrio cholerae infection)	NA	NA	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306]	49.87	58.55	57.64	20.59	16.71	22.77	2.58	1.37	0.01	0.2	up	yes
MSTRG.18638	APOBEC3B	ENST00000402255;ENST00000618553;MSTRG.18638.6;ENST00000407298;ENST00000402182;ENST00000333467	"GO:0003824(catalytic activity);GO:0005634(nucleus);GO:0008152(metabolic process);GO:0008270(zinc ion binding);GO:0010529(negative regulation of transposition);GO:0016787(hydrolase activity);GO:0016814(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0047844(deoxycytidine deaminase activity);GO:0051607(defense response to virus)"	NA	NA	NA	"apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B [Source:HGNC Symbol;Acc:HGNC:17352]"	3.37	3.56	2.45	23.42	27.47	10.1	0.17	-2.57	0.02	0.27	down	yes
MSTRG.1866	ILF2	ENST00000615950;ENST00000361891;ENST00000480213;ENST00000368684;ENST00000368681	"GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006955(immune response);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016740(transferase activity);GO:0030529(ribonucleoprotein complex);GO:0044822(poly(A) RNA binding);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037]	75.04	78.67	72.29	145.5	188.49	120.56	0.49	-1.04	0.03	0.29	down	yes
MSTRG.18688	RP4-756G23.5	ENST00000441316;ENST00000451176	NA	NA	NA	NA	NA	0.99	1.01	1.89	0.03	0.03	0.18	2.13	1.09	0.03	0.28	up	yes
MSTRG.18698	POLR3H	ENST00000396504;ENST00000355209;ENST00000337566;ENST00000431534;ENST00000432789;ENST00000407461;ENST00000442616;ENST00000483837	"GO:0001056(RNA polymerase III activity);GO:0003677(DNA binding);GO:0003899(DNA-directed RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006351(transcription, DNA-templated);GO:0006383(transcription from RNA polymerase III promoter);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0006385(transcription elongation from RNA polymerase III promoter);GO:0006386(termination of RNA polymerase III transcription);GO:0010467(gene expression);GO:0032481(positive regulation of type I interferon production);GO:0043231(intracellular membrane-bounded organelle);GO:0045087(innate immune response);GO:0051607(defense response to virus)"	00230(Purine metabolism);00240(Pyrimidine metabolism);01100(Metabolic pathways);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)	NA	NA	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) [Source:HGNC Symbol;Acc:HGNC:30349]	0.84	0.84	1.1	3.22	3.94	2.8	0.44	-1.19	0.01	0.2	down	yes
MSTRG.18702	XRCC6	ENST00000360079;ENST00000428575;ENST00000464116;ENST00000402580;ENST00000359308;ENST00000405878;ENST00000405506;ENST00000478914	"GO:0000723(telomere maintenance);GO:0000783(nuclear telomere cap complex);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003690(double-stranded DNA binding);GO:0003691(double-stranded telomeric DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005829(cytosol);GO:0006266(DNA ligation);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006351(transcription, DNA-templated);GO:0008022(protein C-terminus binding);GO:0016020(membrane);GO:0016032(viral process);GO:0032481(positive regulation of type I interferon production);GO:0032508(DNA duplex unwinding);GO:0042162(telomeric DNA binding);GO:0043564(Ku70:Ku80 complex);GO:0044212(transcription regulatory region DNA binding);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051575(5'-deoxyribose-5-phosphate lyase activity);GO:0070419(nonhomologous end joining complex);GO:0075713(establishment of integrated proviral latency)"	03450(Non-homologous end-joining)	NA	NA	X-ray repair complementing defective repair in Chinese hamster cells 6 [Source:HGNC Symbol;Acc:HGNC:4055]	97.49	96.76	102.59	247.7	279.5	169.19	0.4	-1.31	0.02	0.27	down	yes
MSTRG.18706	C22orf46	MSTRG.18706.1;MSTRG.18706.2;ENST00000472110;MSTRG.18706.4;ENST00000402966	GO:0005576(extracellular region)	NA	NA	NA	chromosome 22 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:26294]	1.27	1.16	1.37	4.54	5.04	2.73	0.42	-1.25	0.02	0.28	down	yes
MSTRG.18711	CENPM	ENST00000215980;ENST00000472374;ENST00000404067;ENST00000402338;ENST00000407253;ENST00000402420;ENST00000396437;ENST00000460824	GO:0000278(mitotic cell cycle);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0007264(small GTPase mediated signal transduction);GO:0034080(CENP-A containing nucleosome assembly)	NA	NA	NA	centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352]	0.89	0.77	0.84	10.28	16.93	6.84	0.15	-2.73	0.01	0.23	down	yes
MSTRG.18733	RRP7A	ENST00000323013;ENST00000416699;ENST00000483303	GO:0000028(ribosomal small subunit assembly);GO:0000166(nucleotide binding);GO:0001825(blastocyst formation);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0032545(CURI complex);GO:0034456(UTP-C complex);GO:0044822(poly(A) RNA binding)	NA	NA	NA	ribosomal RNA processing 7 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:24286]	2.12	2.37	3.58	6.84	7.73	8.16	0.43	-1.23	0.02	0.26	down	yes
MSTRG.1878	S100A3	ENST00000368713;ENST00000368712	GO:0005509(calcium ion binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding)	NA	NA	NA	S100 calcium binding protein A3 [Source:HGNC Symbol;Acc:HGNC:10493]	2.54	2.17	1.65	9.09	4.83	7.92	0.38	-1.4	0.04	0.31	down	yes
MSTRG.18792	TRMU	ENST00000454366;MSTRG.18792.1;ENST00000466510;ENST00000479645;ENST00000491863;ENST00000476901;ENST00000486620;ENST00000441818;ENST00000381021;ENST00000453630;ENST00000456595;ENST00000457572;ENST00000290846;MSTRG.18792.14;ENST00000381019;ENST00000465378;ENST00000496831;ENST00000485175;ENST00000493556;ENST00000479648;ENST00000491612;ENST00000485559;ENST00000470831	GO:0000049(tRNA binding);GO:0002143(tRNA wobble position uridine thiolation);GO:0004808(tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0008033(tRNA processing);GO:0016740(transferase activity);GO:0016783(sulfurtransferase activity);GO:0030488(tRNA methylation)	04122(Sulfur relay system)	NA	NA	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase [Source:HGNC Symbol;Acc:HGNC:25481]	1.77	1.77	2.21	18.55	21.94	7.22	0.15	-2.71	0.02	0.27	down	yes
MSTRG.18793	CELSR1	ENST00000262738;ENST00000473624;MSTRG.18793.4;MSTRG.18793.3;ENST00000454637;ENST00000497509	GO:0001736(establishment of planar polarity);GO:0001764(neuron migration);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007266(Rho protein signal transduction);GO:0007417(central nervous system development);GO:0007626(locomotory behavior);GO:0009952(anterior/posterior pattern specification);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032956(regulation of actin cytoskeleton organization);GO:0042060(wound healing);GO:0042249(establishment of planar polarity of embryonic epithelium);GO:0042472(inner ear morphogenesis);GO:0045176(apical protein localization);GO:0046983(protein dimerization activity);GO:0048105(establishment of body hair planar orientation);GO:0060488(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060489(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060490(lateral sprouting involved in lung morphogenesis);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0090251(protein localization involved in establishment of planar polarity)	NA	NA	NA	"cadherin, EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850]"	3.84	3.52	5.41	0.63	0.69	0.85	3.18	1.67	0.01	0.19	up	yes
MSTRG.18798	CERK	ENST00000216264;ENST00000443629;ENST00000471929	GO:0000287(magnesium ion binding);GO:0001729(ceramide kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0006665(sphingolipid metabolic process);GO:0006672(ceramide metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0044281(small molecule metabolic process);GO:0046834(lipid phosphorylation)	00600(Sphingolipid metabolism)	NA	NA	ceramide kinase [Source:HGNC Symbol;Acc:HGNC:19256]	4.51	6.72	4.36	9.42	13.32	8.76	0.48	-1.06	0.04	0.33	down	yes
MSTRG.18824	CRELD2	ENST00000450207;ENST00000404488;ENST00000328268;ENST00000483652;ENST00000403427;ENST00000407217;ENST00000482956;ENST00000498354;ENST00000444954;ENST00000487969	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus)	NA	NA	NA	cysteine-rich with EGF-like domains 2 [Source:HGNC Symbol;Acc:HGNC:28150]	4.53	4.73	3.77	10.17	11.3	13.04	0.45	-1.15	0.01	0.2	down	yes
MSTRG.18826	MIR6821	ENST00000617625	NA	NA	NA	NA	NA	16.58	7.18	17.91	3.45	2.85	1.98	4.34	2.12	0.03	0.3	up	yes
MSTRG.18828	.	MSTRG.18828.1	NA	NA	NA	NA	NA	1.56	0.61	0.69	0.04	0	0.26	2.15	1.11	0.01	0.21	up	yes
MSTRG.18831	PANX2	ENST00000395842;MSTRG.18831.3	NA	NA	NA	NA	NA	7.92	7.22	8.09	2.47	2.5	1.66	2.65	1.4	0.01	0.19	up	yes
MSTRG.18847	ADM2	ENST00000395738	GO:0001525(angiogenesis);GO:0005179(hormone activity);GO:0005576(extracellular region);GO:0006468(protein phosphorylation);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007586(digestion);GO:0007631(feeding behavior);GO:0010628(positive regulation of gene expression);GO:0032403(protein complex binding);GO:0045766(positive regulation of angiogenesis);GO:0045776(negative regulation of blood pressure)	NA	NA	NA	adrenomedullin 2 [Source:HGNC Symbol;Acc:HGNC:28898]	1.94	2.57	5.11	0.12	0.14	0.06	3.27	1.71	0.03	0.29	up	yes
MSTRG.18849	NCAPH2	MSTRG.18849.1;ENST00000420993;ENST00000395698;ENST00000395701;ENST00000518394;ENST00000523045;ENST00000418794;ENST00000299821;ENST00000520297	GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0016020(membrane);GO:0030261(chromosome condensation)	NA	NA	NA	"non-SMC condensin II complex, subunit H2 [Source:HGNC Symbol;Acc:HGNC:25071]"	5.89	5.7	7.41	19.41	20.22	13.8	0.37	-1.45	0.01	0.23	down	yes
MSTRG.1886	CRTC2	ENST00000303569;ENST00000461638;ENST00000368630;MSTRG.1886.2;ENST00000368633;ENST00000487235;ENST00000524997;ENST00000467860;ENST00000493909;ENST00000476883;ENST00000492073	"GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006094(gluconeogenesis);GO:0006351(transcription, DNA-templated);GO:0008140(cAMP response element binding protein binding);GO:0016032(viral process);GO:0032793(positive regulation of CREB transcription factor activity);GO:0042593(glucose homeostasis);GO:0043970(histone H3-K9 acetylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051289(protein homotetramerization);GO:0070062(extracellular exosome);GO:1901998(toxin transport)"	NA	NA	NA	CREB regulated transcription coactivator 2 [Source:HGNC Symbol;Acc:HGNC:27301]	20.09	18.08	17.09	7.64	7.77	9.24	2.28	1.19	0	0.14	up	yes
MSTRG.18879	BHLHE40	MSTRG.18879.1;ENST00000256495;ENST00000467610;ENST00000460806	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001191(RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003705(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005794(Golgi apparatus);GO:0006355(regulation of transcription, DNA-templated);GO:0007623(circadian rhythm);GO:0009416(response to light stimulus);GO:0019904(protein domain specific binding);GO:0032922(circadian regulation of gene expression);GO:0042803(protein homodimerization activity);GO:0043153(entrainment of circadian clock by photoperiod);GO:0043425(bHLH transcription factor binding);GO:0043426(MRF binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0046983(protein dimerization activity);GO:0070888(E-box binding)"	04710(Circadian rhythm - mammal)	NA	NA	"basic helix-loop-helix family, member e40 [Source:HGNC Symbol;Acc:HGNC:1046]"	108.93	118.87	155.16	19.58	13.11	18.41	6.64	2.73	0	0.17	up	yes
MSTRG.18931	FANCD2	ENST00000287647;ENST00000383807;ENST00000435522;ENST00000419585;ENST00000431693;MSTRG.18931.5;ENST00000438741;MSTRG.18931.9;ENST00000464934;ENST00000421731;ENST00000470757;ENST00000480909	GO:0000793(condensed chromosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007129(synapsis);GO:0007276(gamete generation);GO:0010332(response to gamma radiation);GO:0043231(intracellular membrane-bounded organelle);GO:0070182(DNA polymerase binding)	NA	NA	NA	"Fanconi anemia, complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585]"	0.85	0.88	0.52	8.69	7.21	3.04	0.21	-2.28	0.02	0.26	down	yes
MSTRG.18935	BRK1	ENST00000530758;MSTRG.18935.2	NA	NA	NA	NA	NA	154.2	144	137.19	41.81	35.37	53.73	3.58	1.84	0	0.18	up	yes
MSTRG.19055	NR1D2	ENST00000312521;ENST00000383773;ENST00000492552;ENST00000468700;ENST00000472780	"GO:0001046(core promoter sequence-specific DNA binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0019216(regulation of lipid metabolic process);GO:0030522(intracellular receptor signaling pathway);GO:0042752(regulation of circadian rhythm);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0050727(regulation of inflammatory response);GO:0055088(lipid homeostasis);GO:2000505(regulation of energy homeostasis);GO:2001014(regulation of skeletal muscle cell differentiation)"	NA	NA	NA	"nuclear receptor subfamily 1, group D, member 2 [Source:HGNC Symbol;Acc:HGNC:7963]"	17.31	15.89	12.94	2.86	4.16	2.63	4.06	2.02	0.01	0.19	up	yes
MSTRG.19063	RARB	ENST00000437042;ENST00000330688;ENST00000489694;ENST00000462272;ENST00000479097;ENST00000480001;ENST00000458646	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001657(ureteric bud development);GO:0002068(glandular epithelial cell development);GO:0003148(outflow tract septum morphogenesis);GO:0003406(retinal pigment epithelium development);GO:0003417(growth plate cartilage development);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0003708(retinoic acid receptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0008144(drug binding);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0010467(gene expression);GO:0021756(striatum development);GO:0022008(neurogenesis);GO:0031641(regulation of myelination);GO:0032331(negative regulation of chondrocyte differentiation);GO:0032403(protein complex binding);GO:0035116(embryonic hindlimb morphogenesis);GO:0035264(multicellular organism growth);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043068(positive regulation of programmed cell death);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045666(positive regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046965(retinoid X receptor binding);GO:0048048(embryonic eye morphogenesis);GO:0048384(retinoic acid receptor signaling pathway);GO:0048566(embryonic digestive tract development);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060041(retina development in camera-type eye);GO:0060348(bone development);GO:0061037(negative regulation of cartilage development)"	05200(Pathways in cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer)	NA	NA	"retinoic acid receptor, beta [Source:HGNC Symbol;Acc:HGNC:9865]"	1.2	1.17	1.17	7.22	4.79	5.32	0.3	-1.76	0	0.17	down	yes
MSTRG.19151	CTDSPL	ENST00000443503;ENST00000273179;ENST00000435525;ENST00000486978;ENST00000310189;ENST00000416688;ENST00000447745;ENST00000436654	GO:0001933(negative regulation of protein phosphorylation);GO:0003674(molecular_function);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0008150(biological_process);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)	NA	NA	NA	"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like [Source:HGNC Symbol;Acc:HGNC:16890]"	1.76	1.94	3.32	8.15	9.02	5.38	0.35	-1.52	0.03	0.28	down	yes
MSTRG.19168	CSRNP1	ENST00000273153;ENST00000514182	"GO:0001228(RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003674(molecular_function);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0009791(post-embryonic development);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0060021(palate development);GO:0060325(face morphogenesis)"	NA	NA	NA	cysteine-serine-rich nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:14300]	5.38	11.7	10.6	1.56	1.98	1.51	2.88	1.52	0.02	0.25	up	yes
MSTRG.19176	EIF1B	ENST00000232905;ENST00000462088;ENST00000488260;ENST00000487151	GO:0003743(translation initiation factor activity);GO:0005575(cellular_component);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0044822(poly(A) RNA binding)	03013(RNA transport)	NA	NA	eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792]	67.43	68.9	50.99	23.35	26.93	18.94	2.54	1.35	0.02	0.25	up	yes
MSTRG.19217	ANO10	MSTRG.19217.1;MSTRG.19217.3;ENST00000292246;MSTRG.19217.5;ENST00000350459;ENST00000396091;ENST00000414522;ENST00000451430;ENST00000448045;ENST00000427171;ENST00000428472;ENST00000444344;ENST00000456438;ENST00000413397;ENST00000439141;ENST00000486959;ENST00000495772	GO:0005227(calcium activated cation channel activity);GO:0005229(intracellular calcium activated chloride channel activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0006812(cation transport);GO:0006821(chloride transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:1902476(chloride transmembrane transport)	NA	NA	NA	anoctamin 10 [Source:HGNC Symbol;Acc:HGNC:25519]	11.22	8.24	10.8	4.92	5.17	4.33	2.04	1.03	0.01	0.23	up	yes
MSTRG.19239	TMEM42	ENST00000326047;ENST00000438321;ENST00000425755;ENST00000422209;MSTRG.19239.9;MSTRG.19239.8;MSTRG.19239.10;ENST00000302392;MSTRG.19239.13;ENST00000477126	GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444]	1.6	2.18	1.58	5.42	4.31	2.48	0.45	-1.15	0.02	0.27	down	yes
MSTRG.19287	CDC25A	ENST00000302506;ENST00000351231;MSTRG.19287.3;MSTRG.19287.4;ENST00000459900;ENST00000443342;ENST00000437972	GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000087(mitotic M phase);GO:0000278(mitotic cell cycle);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006470(protein dephosphorylation);GO:0007067(mitotic nuclear division);GO:0008283(cell proliferation);GO:0009314(response to radiation);GO:0019901(protein kinase binding);GO:0034644(cellular response to UV);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0051301(cell division);GO:0051726(regulation of cell cycle)	04110(Cell cycle);04914(Progesterone-mediated oocyte maturation)	NA	NA	cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725]	2.01	2.47	2.24	10.59	13.8	5.36	0.26	-1.92	0.03	0.28	down	yes
MSTRG.19300	SHISA5	ENST00000619810;ENST00000296444;ENST00000444115;ENST00000466424;ENST00000494854;ENST00000426002;ENST00000465449;ENST00000612611;MSTRG.19300.8;ENST00000417962;ENST00000442747;ENST00000443308;ENST00000460758;ENST00000497863;ENST00000486344;ENST00000424965;ENST00000417841;ENST00000415268;ENST00000441507;ENST00000490864;ENST00000496408	GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050699(WW domain binding);GO:0070062(extracellular exosome);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator)	04115(p53 signaling pathway)	NA	NA	shisa family member 5 [Source:HGNC Symbol;Acc:HGNC:30376]	27.27	26.72	26.1	7.17	11.73	16	2.8	1.49	0.02	0.27	up	yes
MSTRG.19313	ARIH2OS	ENST00000408959	GO:0016021(integral component of membrane)	NA	NA	NA	ariadne homolog 2 opposite strand [Source:HGNC Symbol;Acc:HGNC:34425]	2.31	1.88	1.91	0	0	0	3.18	1.67	0	0.08	up	yes
MSTRG.19325	QRICH1	ENST00000395443;MSTRG.19325.2;MSTRG.19325.3;ENST00000498392;ENST00000357496;ENST00000424300;ENST00000477021;ENST00000469910;ENST00000498440;ENST00000437939;ENST00000450685;ENST00000411682;ENST00000430979	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0008150(biological_process);GO:0042981(regulation of apoptotic process)	NA	NA	NA	glutamine-rich 1 [Source:HGNC Symbol;Acc:HGNC:24713]	4.73	5.66	7.52	13.28	13.94	10.62	0.46	-1.13	0.02	0.26	down	yes
MSTRG.19331	CCDC71	ENST00000321895	NA	NA	NA	NA	coiled-coil domain containing 71 [Source:HGNC Symbol;Acc:HGNC:25760]	0.7	1.79	4.41	13.22	13.48	14.78	0.17	-2.59	0.03	0.29	down	yes
MSTRG.19338	RHOA	ENST00000418115;ENST00000454011;ENST00000422781;ENST00000445425;ENST00000431929;ENST00000265538	"GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005768(endosome);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0007165(signal transduction);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007264(small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0007411(axon guidance);GO:0007596(blood coagulation);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0017022(myosin binding);GO:0021762(substantia nigra development);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0030168(platelet activation);GO:0030334(regulation of cell migration);GO:0030496(midbody);GO:0031982(vesicle);GO:0032154(cleavage furrow);GO:0032467(positive regulation of cytokinesis);GO:0033688(regulation of osteoblast proliferation);GO:0036089(cleavage furrow formation);GO:0038027(apolipoprotein A-I-mediated signaling pathway);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043296(apical junction complex);GO:0043297(apical junction assembly);GO:0043931(ossification involved in bone maturation);GO:0044319(wound healing, spreading of cells);GO:0045666(positive regulation of neuron differentiation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0050770(regulation of axonogenesis);GO:0050771(negative regulation of axonogenesis);GO:0050772(positive regulation of axonogenesis);GO:0050919(negative chemotaxis);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051496(positive regulation of stress fiber assembly);GO:0060193(positive regulation of lipase activity);GO:0061383(trabecula morphogenesis);GO:0070062(extracellular exosome);GO:0090307(mitotic spindle assembly);GO:1902766(skeletal muscle satellite cell migration)"	04062(Chemokine signaling pathway);04144(Endocytosis);04270(Vascular smooth muscle contraction);04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04360(Axon guidance);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04660(T cell receptor signaling pathway);04670(Leukocyte transendothelial migration);04722(Neurotrophin signaling pathway);04810(Regulation of actin cytoskeleton);04972(Pancreatic secretion);05100(Bacterial invasion of epithelial cells);05130(Pathogenic Escherichia coli infection);05152(Tuberculosis);05200(Pathways in cancer);05210(Colorectal cancer)	NA	NA	ras homolog family member A [Source:HGNC Symbol;Acc:HGNC:667]	47.85	116.3	112.1	171.77	206.87	169.84	0.35	-1.52	0.04	0.32	down	yes
MSTRG.1934	EFNA1	ENST00000368407;ENST00000368406;ENST00000469878;ENST00000474413;ENST00000497282	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000187(activation of MAPK activity);GO:0001525(angiogenesis);GO:0003180(aortic valve morphogenesis);GO:0003183(mitral valve morphogenesis);GO:0003199(endocardial cushion to mesenchymal transition involved in heart valve formation);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0007411(axon guidance);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0014028(notochord formation);GO:0016020(membrane);GO:0016477(cell migration);GO:0030182(neuron differentiation);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0046658(anchored component of plasma membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050770(regulation of axonogenesis);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0070062(extracellular exosome)	04360(Axon guidance)	NA	NA	ephrin-A1 [Source:HGNC Symbol;Acc:HGNC:3221]	35.49	25.15	23.4	5.68	5.64	20.19	4.31	2.11	0.05	0.33	up	yes
MSTRG.19353	TRAIP	ENST00000331456;ENST00000491060;ENST00000473195;ENST00000469027;ENST00000475495;ENST00000482582;ENST00000488860;ENST00000482243;ENST00000477546;ENST00000489948;ENST00000473863	GO:0004842(ubiquitin-protein transferase activity);GO:0005057(receptor signaling protein activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0008270(zinc ion binding);GO:0008283(cell proliferation);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0032688(negative regulation of interferon-beta production);GO:0035556(intracellular signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0061630(ubiquitin protein ligase activity)	NA	NA	NA	TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764]	0.92	1.27	1.15	5.89	6.63	2.93	0.3	-1.75	0.02	0.25	down	yes
MSTRG.19407	POC1A	MSTRG.19407.1	NA	NA	NA	NA	NA	0.08	0.13	0.07	1.63	1.02	0.67	0.46	-1.11	0.01	0.23	down	yes
MSTRG.19408	POC1A	MSTRG.19408.1;ENST00000296484;ENST00000394970;MSTRG.19408.4;ENST00000474012	GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005814(centriole);GO:0030030(cell projection organization);GO:0036064(ciliary basal body)	NA	NA	NA	POC1 centriolar protein A [Source:HGNC Symbol;Acc:HGNC:24488]	2.28	1.47	1.01	7.5	8.33	4.43	0.34	-1.56	0.04	0.33	down	yes
MSTRG.19421	PHF7	MSTRG.19421.1	NA	NA	NA	NA	NA	0.19	0.93	0.61	2.36	1.95	2.14	0.41	-1.3	0	0.17	down	yes
MSTRG.19425	NT5DC2	ENST00000463947;MSTRG.19425.1;MSTRG.19425.2;ENST00000479024;ENST00000307076;MSTRG.19425.4;MSTRG.19425.5;ENST00000422318;ENST00000462261;ENST00000459839;ENST00000492555;ENST00000469616;ENST00000466112;ENST00000478091;ENST00000489316;ENST00000486792;ENST00000471522;ENST00000487779;ENST00000490681	GO:0008253(5'-nucleotidase activity);GO:0016311(dephosphorylation);GO:0046872(metal ion binding)	NA	NA	NA	5'-nucleotidase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25717]	8.71	9.7	10.35	28.69	34.47	24.43	0.33	-1.59	0	0.18	down	yes
MSTRG.19431	SNORD19	ENST00000391191	NA	NA	NA	NA	NA	2.45	1.48	1.47	0.65	0.16	0.29	2.13	1.09	0.04	0.32	up	yes
MSTRG.195	ENO1	ENST00000234590;ENST00000464920;ENST00000497492;ENST00000486051;ENST00000492343;ENST00000489867	"GO:0000015(phosphopyruvate hydratase complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000287(magnesium ion binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0004634(phosphopyruvate hydratase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006094(gluconeogenesis);GO:0006096(glycolytic process);GO:0006351(transcription, DNA-templated);GO:0009615(response to virus);GO:0016020(membrane);GO:0030308(negative regulation of cell growth);GO:0031430(M band);GO:0044281(small molecule metabolic process);GO:0044822(poly(A) RNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051020(GTPase binding);GO:0061621(canonical glycolysis);GO:0070062(extracellular exosome)"	00010(Glycolysis / Gluconeogenesis);01100(Metabolic pathways);03018(RNA degradation)	NA	NA	"enolase 1, (alpha) [Source:HGNC Symbol;Acc:HGNC:3350]"	246.98	280.87	329.52	567.43	698.64	547.84	0.45	-1.15	0.01	0.24	down	yes
MSTRG.19583	EPHA3	ENST00000336596;ENST00000452448;ENST00000494014	"GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0005004(GPI-linked ephrin receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007155(cell adhesion);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007411(axon guidance);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0010976(positive regulation of neuron projection development);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0032956(regulation of actin cytoskeleton organization);GO:0043087(regulation of GTPase activity);GO:0048013(ephrin receptor signaling pathway);GO:0051893(regulation of focal adhesion assembly);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0071300(cellular response to retinoic acid);GO:0097155(fasciculation of sensory neuron axon);GO:0097156(fasciculation of motor neuron axon)"	04360(Axon guidance)	NA	NA	EPH receptor A3 [Source:HGNC Symbol;Acc:HGNC:3387]	1.41	1.88	1.31	9.2	6.46	6.7	0.26	-1.93	0	0.14	down	yes
MSTRG.19613	CMSS1	MSTRG.19613.2;MSTRG.19613.3;MSTRG.19613.1;ENST00000463753;ENST00000483969;ENST00000474648;ENST00000452013;ENST00000261037;ENST00000273342;ENST00000621757;ENST00000462604;ENST00000421999;ENST00000463526;ENST00000491299;ENST00000496116;ENST00000489081;ENST00000478909;ENST00000497345;ENST00000479555;ENST00000494412	GO:0044822(poly(A) RNA binding)	NA	NA	NA	cms1 ribosomal small subunit homolog (yeast) [Source:HGNC Symbol;Acc:HGNC:28666]	3.05	3.48	3.49	11.48	6.35	8.05	0.4	-1.31	0.02	0.25	down	yes
MSTRG.1964	ARHGEF2	MSTRG.1964.2;MSTRG.1964.1;ENST00000313695;ENST00000361247;MSTRG.1964.4;ENST00000462460;ENST00000477754;ENST00000470541;MSTRG.1964.8;MSTRG.1964.11;MSTRG.1964.10;ENST00000368315;ENST00000313667;ENST00000474428;ENST00000470975;ENST00000608543;ENST00000470874;ENST00000471589;ENST00000497907;ENST00000476273;ENST00000609707;ENST00000487755;ENST00000465079;ENST00000495070;ENST00000423422;ENST00000609126	GO:0000132(establishment of mitotic spindle orientation);GO:0000902(cell morphogenesis);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005819(spindle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005923(bicellular tight junction);GO:0005925(focal adhesion);GO:0006886(intracellular protein transport);GO:0007015(actin filament organization);GO:0007026(negative regulation of microtubule depolymerization);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0008017(microtubule binding);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0017048(Rho GTPase binding);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0031982(vesicle);GO:0032587(ruffle membrane);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0042127(regulation of cell proliferation);GO:0043025(neuronal cell body);GO:0043065(positive regulation of apoptotic process);GO:0043198(dendritic shaft);GO:0043234(protein complex);GO:0043547(positive regulation of GTPase activity);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048365(Rac GTPase binding);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050768(negative regulation of neurogenesis);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051301(cell division);GO:0060546(negative regulation of necroptotic process);GO:0071225(cellular response to muramyl dipeptide);GO:0071356(cellular response to tumor necrosis factor);GO:0071474(cellular hyperosmotic response);GO:0097190(apoptotic signaling pathway);GO:0097481(neuronal postsynaptic density);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902219(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)	05130(Pathogenic Escherichia coli infection)	NA	NA	Rho/Rac guanine nucleotide exchange factor (GEF) 2 [Source:HGNC Symbol;Acc:HGNC:682]	25.36	36	42.29	10.41	10.82	13.53	2.6	1.38	0.02	0.28	up	yes
MSTRG.19666	KIAA1524	ENST00000295746;ENST00000491772;ENST00000619684;ENST00000481530;ENST00000487834;ENST00000461666	GO:0005488(binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007283(spermatogenesis);GO:0016021(integral component of membrane);GO:2000179(positive regulation of neural precursor cell proliferation)	NA	NA	NA	KIAA1524 [Source:HGNC Symbol;Acc:HGNC:29302]	0.7	1.04	0.56	10.76	8.5	1.88	0.17	-2.53	0.04	0.33	down	yes
MSTRG.19706	GAP43	ENST00000305124;ENST00000393780	GO:0001786(phosphatidylserine binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0009611(response to wounding);GO:0010001(glial cell differentiation);GO:0014069(postsynaptic density);GO:0016198(axon choice point recognition);GO:0030054(cell junction);GO:0030424(axon);GO:0031527(filopodium membrane);GO:0032584(growth cone membrane);GO:0035727(lysophosphatidic acid binding);GO:0040008(regulation of growth);GO:0042246(tissue regeneration);GO:0045165(cell fate commitment);GO:0051489(regulation of filopodium assembly);GO:0071944(cell periphery);GO:0097481(neuronal postsynaptic density);GO:1901981(phosphatidylinositol phosphate binding)	NA	NA	NA	growth associated protein 43 [Source:HGNC Symbol;Acc:HGNC:4140]	0.08	0.03	0.06	1.74	2.36	1.15	0.38	-1.4	0.01	0.24	down	yes
MSTRG.19734	TMEM39A	ENST00000473684;ENST00000438581;ENST00000319172;ENST00000468545;ENST00000491685;ENST00000486159;ENST00000486235;ENST00000468676;ENST00000490099;ENST00000497993;ENST00000482162;ENST00000461654	GO:0002230(positive regulation of defense response to virus by host);GO:0016021(integral component of membrane);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	NA	NA	NA	transmembrane protein 39A [Source:HGNC Symbol;Acc:HGNC:25600]	9.26	12.1	12.49	4.39	3.9	5.31	2.09	1.07	0.02	0.26	up	yes
MSTRG.19747	FSTL1	ENST00000295633;MSTRG.19747.2;ENST00000424703;ENST00000488318;ENST00000468098;ENST00000464690;ENST00000472536;ENST00000485968;ENST00000467994	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008201(heparin binding);GO:0030509(BMP signaling pathway);GO:0042594(response to starvation);GO:0070062(extracellular exosome)	NA	NA	NA	follistatin-like 1 [Source:HGNC Symbol;Acc:HGNC:3972]	4.72	4.51	3.31	12.49	12.91	15.4	0.38	-1.4	0.01	0.2	down	yes
MSTRG.19763	EAF2	ENST00000490434;ENST00000465664;ENST00000273668;ENST00000451944;ENST00000490477	"GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0008023(transcription elongation factor complex);GO:0016607(nuclear speck);GO:0030308(negative regulation of cell growth);GO:0032783(ELL-EAF complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060770(negative regulation of epithelial cell proliferation involved in prostate gland development)"	NA	NA	NA	ELL associated factor 2 [Source:HGNC Symbol;Acc:HGNC:23115]	1.87	2.17	1.73	0.32	0.39	0.33	2.11	1.08	0	0.14	up	yes
MSTRG.1977	KIAA0907	MSTRG.1977.2;MSTRG.1977.1;ENST00000368321;ENST00000368320;MSTRG.1977.5;MSTRG.1977.6;ENST00000478002;ENST00000466520;ENST00000465953;ENST00000483237;ENST00000368319;ENST00000482337;ENST00000466713;ENST00000491599	GO:0003723(RNA binding);GO:0005515(protein binding)	NA	NA	NA	KIAA0907 [Source:HGNC Symbol;Acc:HGNC:29145]	32.04	34.86	22.13	8.48	10.62	10.63	2.9	1.54	0.02	0.25	up	yes
MSTRG.19785	ROPN1	ENST00000184183;ENST00000487124;ENST00000479867	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007264(small GTPase mediated signal transduction)	NA	NA	NA	rhophilin associated tail protein 1 [Source:HGNC Symbol;Acc:HGNC:17692]	0.16	0.23	0.09	1.28	1.22	1.26	0.5	-1.01	0	0.12	down	yes
MSTRG.19787	UMPS	ENST00000232607;ENST00000462091;MSTRG.19787.3;ENST00000628619;ENST00000467167;ENST00000460034;ENST00000474588;ENST00000479719;ENST00000497791;ENST00000498715;ENST00000487622;ENST00000495751	GO:0003824(catalytic activity);GO:0004588(orotate phosphoribosyltransferase activity);GO:0004590(orotidine-5'-phosphate decarboxylase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0006222(UMP biosynthetic process);GO:0007565(female pregnancy);GO:0007595(lactation);GO:0008152(metabolic process);GO:0009116(nucleoside metabolic process);GO:0016740(transferase activity);GO:0035690(cellular response to drug);GO:0044205('de novo' UMP biosynthetic process);GO:0044281(small molecule metabolic process);GO:0046134(pyrimidine nucleoside biosynthetic process);GO:0055086(nucleobase-containing small molecule metabolic process)	NA	NA	NA	uridine monophosphate synthetase [Source:HGNC Symbol;Acc:HGNC:12563]	1.65	1.84	2.59	5.11	5.91	3.78	0.47	-1.09	0.03	0.28	down	yes
MSTRG.19801	HEG1	MSTRG.19801.1;ENST00000311127;ENST00000487661;ENST00000480667;ENST00000482699;ENST00000488654	GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0001885(endothelial cell development);GO:0001886(endothelial cell morphogenesis);GO:0001944(vasculature development);GO:0001945(lymph vessel development);GO:0003017(lymph circulation);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003281(ventricular septum development);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005911(cell-cell junction);GO:0007043(cell-cell junction assembly);GO:0007507(heart development);GO:0009791(post-embryonic development);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016021(integral component of membrane);GO:0030324(lung development);GO:0035264(multicellular organism growth);GO:0045216(cell-cell junction organization);GO:0048845(venous blood vessel morphogenesis);GO:0050878(regulation of body fluid levels);GO:0055017(cardiac muscle tissue growth);GO:0060039(pericardium development);GO:0090271(positive regulation of fibroblast growth factor production)	NA	NA	NA	heart development protein with EGF-like domains 1 [Source:HGNC Symbol;Acc:HGNC:29227]	2.43	2.39	2.65	7.83	5.28	6.57	0.44	-1.18	0.01	0.22	down	yes
MSTRG.19832	MCM2	ENST00000265056;ENST00000474964;ENST00000480910;ENST00000472731;ENST00000477668;ENST00000468659;ENST00000491422;ENST00000473785;ENST00000468414	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000785(chromatin);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003688(DNA replication origin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005664(nuclear origin of replication recognition complex);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006334(nucleosome assembly);GO:0007049(cell cycle);GO:0015630(microtubule cytoskeleton);GO:0032508(DNA duplex unwinding);GO:0042393(histone binding);GO:0042555(MCM complex);GO:0046872(metal ion binding);GO:0071353(cellular response to interleukin-4)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944]	4.58	5.65	4.81	32.94	32.67	25.98	0.17	-2.55	0	0.1	down	yes
MSTRG.19836	.	MSTRG.19836.1	NA	NA	NA	NA	NA	1.34	0.25	0.43	0	0	0	2.01	1.01	0.03	0.28	up	yes
MSTRG.19841	RUVBL1	ENST00000585057;ENST00000472125;ENST00000464873;ENST00000322623;ENST00000582176;ENST00000478892;ENST00000480616;ENST00000478243	"GO:0000812(Swr1 complex);GO:0003678(DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005815(microtubule organizing center);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007067(mitotic nuclear division);GO:0007283(spermatogenesis);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0031011(Ino80 complex);GO:0032508(DNA duplex unwinding);GO:0034080(CENP-A containing nucleosome assembly);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0051301(cell division);GO:0070062(extracellular exosome);GO:0071339(MLL1 complex);GO:1903146(regulation of mitochondrion degradation);GO:1903955(positive regulation of protein targeting to mitochondrion)"	04310(Wnt signaling pathway)	NA	NA	RuvB-like AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:10474]	4.72	6.03	8.33	15.8	20.48	18.26	0.36	-1.46	0.02	0.26	down	yes
MSTRG.19854	ACAD9	ENST00000505602;ENST00000514643;MSTRG.19854.3;ENST00000308982;ENST00000512801;ENST00000505192;ENST00000511227;ENST00000514336;ENST00000505867;ENST00000511526;ENST00000508971;ENST00000511325;ENST00000620948	"GO:0003995(acyl-CoA dehydrogenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0030425(dendrite);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)"	NA	NA	NA	"acyl-CoA dehydrogenase family, member 9 [Source:HGNC Symbol;Acc:HGNC:21497]"	2.19	1.96	3.28	8.05	8.15	7.4	0.39	-1.37	0.01	0.23	down	yes
MSTRG.1991	CCT3	ENST00000295688;ENST00000368259;ENST00000368258;ENST00000368261;ENST00000368262;ENST00000472765;ENST00000413555;ENST00000496684;ENST00000533194;ENST00000463132;ENST00000490221;ENST00000478640;ENST00000368256;ENST00000489870	GO:0002199(zona pellucida receptor complex);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005832(chaperonin-containing T-complex);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0007339(binding of sperm to zona pellucida);GO:0043209(myelin sheath);GO:0044267(cellular protein metabolic process);GO:0044297(cell body);GO:0044822(poly(A) RNA binding);GO:0046931(pore complex assembly);GO:0051082(unfolded protein binding);GO:0051084('de novo' posttranslational protein folding);GO:0070062(extracellular exosome);GO:1901998(toxin transport)	NA	NA	NA	"chaperonin containing TCP1, subunit 3 (gamma) [Source:HGNC Symbol;Acc:HGNC:1616]"	70.53	75.52	78.6	151.53	193.09	157.09	0.45	-1.15	0.01	0.2	down	yes
MSTRG.1994	MEF2D	MSTRG.1994.1;ENST00000464356;ENST00000348159;ENST00000360595;ENST00000368240;ENST00000493077;ENST00000489057	"GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0001649(osteoblast differentiation);GO:0001958(endochondral ossification);GO:0002062(chondrocyte differentiation);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0007399(nervous system development);GO:0007512(adult heart development);GO:0007517(muscle organ development);GO:0033613(activating transcription factor binding);GO:0035914(skeletal muscle cell differentiation);GO:0042826(histone deacetylase binding);GO:0043231(intracellular membrane-bounded organelle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046983(protein dimerization activity)"	NA	NA	NA	myocyte enhancer factor 2D [Source:HGNC Symbol;Acc:HGNC:6997]	22.64	19.98	14.37	4.89	4.09	7.75	3.53	1.82	0.02	0.26	up	yes
MSTRG.19945	IL20RB	ENST00000288986;ENST00000481752;ENST00000491539;ENST00000485096;ENST00000476286;ENST00000460960;ENST00000478862;ENST00000488930;ENST00000496489;ENST00000467911;ENST00000482071;ENST00000484501;ENST00000329582;MSTRG.19945.15;ENST00000469964;ENST00000491483;ENST00000475972	GO:0001808(negative regulation of type IV hypersensitivity);GO:0002437(inflammatory response to antigenic stimulus);GO:0002765(immune response-inhibiting signal transduction);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0032689(negative regulation of interferon-gamma production);GO:0032703(negative regulation of interleukin-2 production);GO:0032733(positive regulation of interleukin-10 production);GO:0032753(positive regulation of interleukin-4 production);GO:0042015(interleukin-20 binding);GO:0042130(negative regulation of T cell proliferation);GO:0048873(homeostasis of number of cells within a tissue);GO:0050863(regulation of T cell activation)	04060(Cytokine-cytokine receptor interaction);04630(Jak-STAT signaling pathway)	NA	NA	interleukin 20 receptor beta [Source:HGNC Symbol;Acc:HGNC:6004]	6.76	6.58	7.05	1.81	1.78	1.18	2.95	1.56	0	0.17	up	yes
MSTRG.19951	DBR1	ENST00000260803;MSTRG.19951.2;ENST00000460271;ENST00000477557;ENST00000463982	"GO:0000375(RNA splicing, via transesterification reactions);GO:0000398(mRNA splicing, via spliceosome);GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008419(RNA lariat debranching enzyme activity);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)"	NA	NA	NA	debranching RNA lariats 1 [Source:HGNC Symbol;Acc:HGNC:15594]	2.7	4.16	3.01	8.11	7.91	5.55	0.43	-1.21	0	0.18	down	yes
MSTRG.1996	IQGAP3	MSTRG.1996.2;ENST00000361170;ENST00000491900;ENST00000476565;ENST00000498755;MSTRG.1996.6	NA	NA	NA	NA	NA	4.7	4.6	2.34	21.4	25.31	14.48	0.22	-2.22	0.02	0.26	down	yes
MSTRG.2001	NES	MSTRG.2001.1;ENST00000368223	GO:0000086(G2/M transition of mitotic cell cycle);GO:0003674(molecular_function);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005882(intermediate filament);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0007420(brain development);GO:0019215(intermediate filament binding);GO:0030844(positive regulation of intermediate filament depolymerization);GO:0031076(embryonic camera-type eye development);GO:0032091(negative regulation of protein binding);GO:0043086(negative regulation of catalytic activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045111(intermediate filament cytoskeleton);GO:0048858(cell projection morphogenesis);GO:0072089(stem cell proliferation);GO:2000179(positive regulation of neural precursor cell proliferation)	NA	NA	NA	nestin [Source:HGNC Symbol;Acc:HGNC:7756]	35.77	36.72	36.38	178.67	170.36	118.15	0.22	-2.2	0	0.16	down	yes
MSTRG.20048	WWTR1	MSTRG.20048.3;MSTRG.20048.4;MSTRG.20048.2;ENST00000465804;ENST00000360632;ENST00000471586;ENST00000494754;ENST00000472417;ENST00000485244;ENST00000479238;ENST00000485352;ENST00000460517;ENST00000474080	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001649(osteoblast differentiation);GO:0001933(negative regulation of protein phosphorylation);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006469(negative regulation of protein kinase activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0010467(gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0016567(protein ubiquitination);GO:0017145(stem cell division);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0032835(glomerulus development);GO:0035264(multicellular organism growth);GO:0035329(hippo signaling);GO:0035414(negative regulation of catenin import into nucleus);GO:0042803(protein homodimerization activity);GO:0045599(negative regulation of fat cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048762(mesenchymal cell differentiation);GO:0060271(cilium morphogenesis);GO:0060390(regulation of SMAD protein import into nucleus);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0060993(kidney morphogenesis);GO:0072307(regulation of metanephric nephron tubule epithelial cell differentiation);GO:0090090(negative regulation of canonical Wnt signaling pathway)"	NA	NA	NA	WW domain containing transcription regulator 1 [Source:HGNC Symbol;Acc:HGNC:24042]	4.05	5.35	3.18	13.01	11	16.72	0.35	-1.52	0.02	0.27	down	yes
MSTRG.20066	SIAH2	ENST00000312960;ENST00000482706	GO:0003714(transcription corepressor activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007049(cell cycle);GO:0007264(small GTPase mediated signal transduction);GO:0007275(multicellular organismal development);GO:0007411(axon guidance);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0031396(regulation of protein ubiquitination);GO:0031624(ubiquitin conjugating enzyme binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0044257(cellular protein catabolic process);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)	NA	NA	NA	siah E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:10858]	23.67	21.55	19.55	6.24	8.72	10.39	2.84	1.51	0.01	0.19	up	yes
MSTRG.20068	SERP1	ENST00000239944;ENST00000491660;ENST00000491195;ENST00000490945;ENST00000463647;ENST00000484608	GO:0001501(skeletal system development);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005881(cytoplasmic microtubule);GO:0006006(glucose metabolic process);GO:0006464(cellular protein modification process);GO:0006486(protein glycosylation);GO:0006950(response to stress);GO:0007009(plasma membrane organization);GO:0009791(post-embryonic development);GO:0010259(multicellular organismal aging);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032024(positive regulation of insulin secretion);GO:0036498(IRE1-mediated unfolded protein response);GO:0044267(cellular protein metabolic process);GO:0045727(positive regulation of translation);GO:0046622(positive regulation of organ growth);GO:0048644(muscle organ morphogenesis);GO:0060124(positive regulation of growth hormone secretion)	NA	NA	NA	stress-associated endoplasmic reticulum protein 1 [Source:HGNC Symbol;Acc:HGNC:10759]	30.16	33.86	31.73	13.18	13.09	8.86	2.32	1.22	0.01	0.21	up	yes
MSTRG.20101	PTX3	ENST00000295927	GO:0001849(complement component C1q binding);GO:0001872((1->3)-beta-D-glucan binding);GO:0001878(response to yeast);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0008228(opsonization);GO:0044869(negative regulation by host of viral exo-alpha-sialidase activity);GO:0044871(negative regulation by host of viral glycoprotein metabolic process);GO:0045087(innate immune response);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0046597(negative regulation of viral entry into host cell);GO:0046790(virion binding);GO:0050766(positive regulation of phagocytosis);GO:1903016(negative regulation of exo-alpha-sialidase activity);GO:1903019(negative regulation of glycoprotein metabolic process)	NA	NA	NA	"pentraxin 3, long [Source:HGNC Symbol;Acc:HGNC:9692]"	69.52	69.67	306.67	1.15	7.8	3.29	31.8	4.99	0.03	0.29	up	yes
MSTRG.20102	CCNL1	MSTRG.20102.1;ENST00000461804;MSTRG.20102.3;ENST00000295926;ENST00000464316;ENST00000471247;ENST00000474539;ENST00000475298;ENST00000631619;ENST00000476744;ENST00000470121;ENST00000468977;ENST00000467849;ENST00000476367;ENST00000477127;ENST00000464679;ENST00000495471;ENST00000481173;ENST00000479052;ENST00000483789;ENST00000478454;ENST00000479596;ENST00000465947;ENST00000467081;ENST00000464575;ENST00000295925;ENST00000471044;ENST00000466101	"GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006396(RNA processing);GO:0016607(nuclear speck);GO:0019901(protein kinase binding)"	NA	NA	NA	cyclin L1 [Source:HGNC Symbol;Acc:HGNC:20569]	7.24	5.05	4.59	2.82	1.93	1.72	2.14	1.1	0.04	0.33	up	yes
MSTRG.20142	KRT8P12	ENST00000468527;MSTRG.20142.2;MSTRG.20142.3	NA	NA	NA	NA	NA	2.26	0.65	1.3	0.17	0.24	0.47	2.4	1.26	0	0.18	up	yes
MSTRG.20148	BCHE	ENST00000264381;ENST00000482958;ENST00000497011;ENST00000479451;ENST00000488954	GO:0001540(beta-amyloid binding);GO:0003824(catalytic activity);GO:0003990(acetylcholinesterase activity);GO:0004104(cholinesterase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005641(nuclear envelope lumen);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0007584(response to nutrient);GO:0007612(learning);GO:0008152(metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0014016(neuroblast differentiation);GO:0016020(membrane);GO:0019695(choline metabolic process);GO:0019899(enzyme binding);GO:0033265(choline binding);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043279(response to alkaloid);GO:0044267(cellular protein metabolic process);GO:0050783(cocaine metabolic process);GO:0050805(negative regulation of synaptic transmission);GO:0051384(response to glucocorticoid);GO:0051593(response to folic acid);GO:0072562(blood microparticle)	NA	NA	NA	butyrylcholinesterase [Source:HGNC Symbol;Acc:HGNC:983]	1.84	2.75	3.67	7.6	5.85	6.68	0.41	-1.27	0.02	0.25	down	yes
MSTRG.20152	GOLIM4	ENST00000470487;MSTRG.20152.2;ENST00000309027;ENST00000479415	GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005796(Golgi lumen);GO:0005801(cis-Golgi network);GO:0006810(transport);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030139(endocytic vesicle);GO:0032580(Golgi cisterna membrane)	NA	NA	NA	golgi integral membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:15448]	2.99	4.4	3.81	11.12	8.23	5.11	0.4	-1.31	0.01	0.23	down	yes
MSTRG.20153	MYNN	ENST00000349841;ENST00000602751;ENST00000356716;ENST00000544106;ENST00000602391	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)"	NA	NA	NA	myoneurin [Source:HGNC Symbol;Acc:HGNC:14955]	6.74	9.66	7.11	2.53	2.34	1.36	2.36	1.24	0.01	0.2	up	yes
MSTRG.2021	AIM2	ENST00000368130;ENST00000612470;ENST00000368129	"GO:0002218(activation of innate immune response);GO:0002230(positive regulation of defense response to virus by host);GO:0003690(double-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032461(positive regulation of protein oligomerization);GO:0032731(positive regulation of interleukin-1 beta production);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0035458(cellular response to interferon-beta);GO:0035690(cellular response to drug);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0050702(interleukin-1 beta secretion);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070269(pyroptosis);GO:0097169(AIM2 inflammasome complex);GO:2001056(positive regulation of cysteine-type endopeptidase activity)"	04623(Cytosolic DNA-sensing pathway)	NA	NA	absent in melanoma 2 [Source:HGNC Symbol;Acc:HGNC:357]	0.26	0.38	0.44	2.86	2.21	1.5	0.34	-1.57	0	0.18	down	yes
MSTRG.20236	KLHL24	ENST00000242810;ENST00000493074;MSTRG.20236.2;ENST00000437402;ENST00000454495;ENST00000461813;ENST00000473045;ENST00000468101;ENST00000427201;ENST00000482138;MSTRG.20236.6;ENST00000454652;MSTRG.20236.13;ENST00000481126;ENST00000475827;ENST00000468001;ENST00000476808;ENST00000492409	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0030424(axon);GO:0043204(perikaryon);GO:2000312(regulation of kainate selective glutamate receptor activity)	NA	NA	NA	kelch-like family member 24 [Source:HGNC Symbol;Acc:HGNC:25947]	7.65	8.29	3.65	0.54	0.28	1.63	4.66	2.22	0.04	0.31	up	yes
MSTRG.2024	ACKR1	MSTRG.2024.1;ENST00000368124;ENST00000416746;ENST00000368122;ENST00000368121	GO:0004872(receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0006952(defense response);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0016021(integral component of membrane);GO:0019956(chemokine binding);GO:0019957(C-C chemokine binding);GO:0055037(recycling endosome);GO:0070098(chemokine-mediated signaling pathway)	05144(Malaria)	NA	NA	atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035]	5.56	3.71	1.75	19.12	16.41	34.85	0.25	-2.02	0.04	0.33	down	yes
MSTRG.20295	PSMD2	ENST00000310118;MSTRG.20295.2;ENST00000417952;ENST00000459910;ENST00000487475;ENST00000492191;ENST00000433010;ENST00000476461;ENST00000445558;ENST00000435761;ENST00000439383;ENST00000463602;ENST00000485937;ENST00000491149;ENST00000460628;ENST00000466987;ENST00000488085;ENST00000432855;ENST00000496925;ENST00000473991;ENST00000491494	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000209(protein polyubiquitination);GO:0000278(mitotic cell cycle);GO:0000502(proteasome complex);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005488(binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005838(proteasome regulatory particle);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006915(apoptotic process);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0010467(gene expression);GO:0012501(programmed cell death);GO:0016020(membrane);GO:0016032(viral process);GO:0022624(proteasome accessory complex);GO:0030234(enzyme regulator activity);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0034641(cellular nitrogen compound metabolic process);GO:0042176(regulation of protein catabolic process);GO:0042590(antigen processing and presentation of exogenous peptide antigen via MHC class I);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0044281(small molecule metabolic process);GO:0045087(innate immune response);GO:0050790(regulation of catalytic activity);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070062(extracellular exosome);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway)"	03050(Proteasome)	NA	NA	"proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 [Source:HGNC Symbol;Acc:HGNC:9559]"	37.3	37.09	39.24	95.18	126.55	66.21	0.39	-1.37	0.04	0.3	down	yes
MSTRG.20296	EIF4G1	ENST00000346169;ENST00000414031;MSTRG.20296.4;MSTRG.20296.5;MSTRG.20296.6;MSTRG.20296.9;MSTRG.20296.10;MSTRG.20296.7;MSTRG.20296.8;ENST00000392537;ENST00000444134;ENST00000442406;ENST00000450424;ENST00000413967;ENST00000426123;MSTRG.20296.18;ENST00000350481;MSTRG.20296.21;ENST00000485712;ENST00000440448;ENST00000427845;ENST00000342981;ENST00000424196;ENST00000456033;ENST00000411531;ENST00000444861;ENST00000484862;ENST00000441154;ENST00000434061;ENST00000493299;ENST00000435046;MSTRG.20296.40;ENST00000466311;ENST00000482303;ENST00000422614;ENST00000460829;ENST00000475721;ENST00000464548;ENST00000478291	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0001662(behavioral fear response);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0005488(binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0008135(translation factor activity, RNA binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0008286(insulin receptor signaling pathway);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0019221(cytokine-mediated signaling pathway);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0045666(positive regulation of neuron differentiation)"	03013(RNA transport);05416(Viral myocarditis)	NA	NA	"eukaryotic translation initiation factor 4 gamma, 1 [Source:HGNC Symbol;Acc:HGNC:3296]"	24.98	24.8	26.99	66.84	70.42	48.22	0.4	-1.33	0.01	0.23	down	yes
MSTRG.20306	EPHB3	ENST00000330394;ENST00000482987;ENST00000473079	"GO:0001525(angiogenesis);GO:0001655(urogenital system development);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006468(protein phosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007411(axon guidance);GO:0007413(axonal fasciculation);GO:0008046(axon guidance receptor activity);GO:0016021(integral component of membrane);GO:0016477(cell migration);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0021952(central nervous system projection neuron axonogenesis);GO:0022038(corpus callosum development);GO:0022407(regulation of cell-cell adhesion);GO:0030425(dendrite);GO:0031290(retinal ganglion cell axon guidance);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043087(regulation of GTPase activity);GO:0046777(protein autophosphorylation);GO:0048013(ephrin receptor signaling pathway);GO:0048538(thymus development);GO:0048546(digestive tract morphogenesis);GO:0050770(regulation of axonogenesis);GO:0051965(positive regulation of synapse assembly);GO:0060021(palate development);GO:0060996(dendritic spine development);GO:0060997(dendritic spine morphogenesis)"	04360(Axon guidance)	NA	NA	EPH receptor B3 [Source:HGNC Symbol;Acc:HGNC:3394]	3.28	1.86	1.22	12.26	10.14	15.84	0.27	-1.88	0.02	0.25	down	yes
MSTRG.20307	TRA2B	ENST00000453386;ENST00000492417;ENST00000463328;ENST00000259043;ENST00000414862;ENST00000466832;ENST00000487615;ENST00000456380;ENST00000382191;ENST00000465245;ENST00000485530;ENST00000493864;ENST00000477939;ENST00000480461	"GO:0000166(nucleotide binding);GO:0000375(RNA splicing, via transesterification reactions);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0021796(cerebral cortex regionalization);GO:0044822(poly(A) RNA binding);GO:0048026(positive regulation of mRNA splicing, via spliceosome)"	NA	NA	NA	transformer 2 beta homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:10781]	7.64	6.47	5.52	19.68	20.46	11.52	0.4	-1.32	0.04	0.33	down	yes
MSTRG.20326	EIF4A2	MSTRG.20326.1;ENST00000445596;MSTRG.20326.3;MSTRG.20326.5;ENST00000323963;ENST00000426808;ENST00000465222;ENST00000491473;ENST00000486805;ENST00000465032;ENST00000465267;ENST00000495049;ENST00000429589;ENST00000425053;ENST00000440191;MSTRG.20326.9;ENST00000485101;ENST00000475653;ENST00000443963;ENST00000498746;ENST00000467585;ENST00000466362;ENST00000468362;ENST00000492144;ENST00000465792;ENST00000475409;ENST00000497177;ENST00000494445;ENST00000461021;ENST00000496382	"GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0003676(nucleic acid binding);GO:0003743(translation initiation factor activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0010467(gene expression);GO:0010501(RNA secondary structure unwinding);GO:0016032(viral process);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0016887(ATPase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0048471(perinuclear region of cytoplasm);GO:1900260(negative regulation of RNA-directed RNA polymerase activity)"	03013(RNA transport)	NA	NA	eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]	78.4	76.95	58.23	24.52	23.58	38.99	2.76	1.46	0.02	0.27	up	yes
MSTRG.20396	TNK2	ENST00000416152;ENST00000381916;ENST00000333602;MSTRG.20396.4;MSTRG.20396.1;MSTRG.20396.3;ENST00000420716;ENST00000428187;MSTRG.20396.9;ENST00000464041;ENST00000439230;ENST00000481865;ENST00000424563;ENST00000478623;ENST00000411741;ENST00000489628;ENST00000478715;ENST00000468680;ENST00000486523;ENST00000438207;ENST00000430929;ENST00000468819;MSTRG.20396.24;ENST00000447060;ENST00000433111;ENST00000427576	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005095(GTPase inhibitor activity);GO:0005154(epidermal growth factor receptor binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0005905(coated pit);GO:0005912(adherens junction);GO:0006468(protein phosphorylation);GO:0006897(endocytosis);GO:0007166(cell surface receptor signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007264(small GTPase mediated signal transduction);GO:0016020(membrane);GO:0016310(phosphorylation);GO:0016477(cell migration);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030136(clathrin-coated vesicle);GO:0030154(cell differentiation);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0030659(cytoplasmic vesicle membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0034260(negative regulation of GTPase activity);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0042127(regulation of cell proliferation);GO:0042802(identical protein binding);GO:0043025(neuronal cell body);GO:0045087(innate immune response);GO:0046872(metal ion binding);GO:0050699(WW domain binding);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0051427(hormone receptor binding);GO:0070436(Grb2-EGFR complex);GO:2000369(regulation of clathrin-mediated endocytosis)"	NA	NA	NA	"tyrosine kinase, non-receptor, 2 [Source:HGNC Symbol;Acc:HGNC:19297]"	5.5	5.98	5.18	1.73	1.7	2.3	2.31	1.21	0	0.18	up	yes
MSTRG.20408	TM4SF19-AS1	ENST00000420226;MSTRG.20408.4	NA	NA	NA	NA	NA	3.76	2.47	2.62	0.42	0.46	0.06	3.15	1.66	0.01	0.23	up	yes
MSTRG.20431	NCBP2-AS2	MSTRG.20431.1	NA	NA	NA	NA	NA	0.05	0.14	0.7	2.04	2.24	2.68	0.38	-1.38	0.03	0.28	down	yes
MSTRG.2048	DEDD	ENST00000468311;ENST00000368010;MSTRG.2048.1;ENST00000472996;ENST00000368006;ENST00000458050;ENST00000545495;ENST00000489249;ENST00000490843;ENST00000486041;ENST00000368005;ENST00000464113;ENST00000473679;ENST00000463227;ENST00000496632	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0007283(spermatogenesis);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0042177(negative regulation of protein catabolic process);GO:0042981(regulation of apoptotic process);GO:0046697(decidualization);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter)"	NA	NA	NA	death effector domain containing [Source:HGNC Symbol;Acc:HGNC:2755]	114.7	98.38	91.95	33.18	37.14	35.07	3.05	1.61	0	0.12	up	yes
MSTRG.2049	PFDN2	MSTRG.2049.1	NA	NA	NA	NA	NA	2.08	6.93	5.2	0.1	0.28	0.05	3.35	1.74	0.02	0.26	up	yes
MSTRG.20497	MAEA	ENST00000303400;ENST00000505177;ENST00000513301;ENST00000512308;ENST00000503653;ENST00000264750;ENST00000502558;ENST00000514708;ENST00000508634;ENST00000503693;ENST00000509531;ENST00000510862;ENST00000510794;ENST00000505839;ENST00000506530;ENST00000503162;ENST00000515766	GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005826(actomyosin contractile ring);GO:0005856(cytoskeleton);GO:0005887(integral component of plasma membrane);GO:0007010(cytoskeleton organization);GO:0007049(cell cycle);GO:0007155(cell adhesion);GO:0007346(regulation of mitotic cell cycle);GO:0015629(actin cytoskeleton);GO:0016363(nuclear matrix);GO:0033033(negative regulation of myeloid cell apoptotic process);GO:0043249(erythrocyte maturation);GO:0048821(erythrocyte development);GO:0048822(enucleate erythrocyte development);GO:0051301(cell division)	NA	NA	NA	macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731]	1.09	1.48	1.59	5.25	5.72	4.52	0.35	-1.5	0	0.15	down	yes
MSTRG.20506	TACC3	ENST00000612220;ENST00000485989;ENST00000484651;ENST00000467746;ENST00000313288;ENST00000617535;ENST00000493975;MSTRG.20506.8;ENST00000458173;ENST00000470136;ENST00000466077;ENST00000470808;ENST00000404054;ENST00000484264	GO:0000226(microtubule cytoskeleton organization);GO:0001666(response to hypoxia);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0008283(cell proliferation);GO:0015630(microtubule cytoskeleton);GO:0019904(protein domain specific binding);GO:0021987(cerebral cortex development);GO:0022008(neurogenesis);GO:0022027(interkinetic nuclear migration);GO:0030097(hemopoiesis);GO:0030953(astral microtubule organization);GO:0032886(regulation of microtubule-based process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0051726(regulation of cell cycle)	03013(RNA transport)	NA	NA	"transforming, acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524]"	1.89	1.5	1.51	28.69	34.4	14.4	0.09	-3.4	0.01	0.2	down	yes
MSTRG.20510	SCARNA22	ENST00000503991	NA	NA	NA	NA	NA	0.55	0.24	0.09	5.43	5.94	4.33	0.22	-2.21	0	0.17	down	yes
MSTRG.20569	S100P	ENST00000296370;ENST00000513778	GO:0000287(magnesium ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0010033(response to organic substance);GO:0031528(microvillus membrane);GO:0043542(endothelial cell migration);GO:0048306(calcium-dependent protein binding);GO:0050786(RAGE receptor binding);GO:0070062(extracellular exosome)	NA	NA	NA	S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504]	8.65	6.68	14.99	0.03	0.19	0.35	10.11	3.34	0	0.19	up	yes
MSTRG.2061	MPZ	ENST00000463290;ENST00000533357;ENST00000491222;MSTRG.2061.3;ENST00000526189;ENST00000476410;ENST00000488271	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005791(rough endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007268(synaptic transmission);GO:0016323(basolateral plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0043209(myelin sheath);GO:0045217(cell-cell junction maintenance)	04514(Cell adhesion molecules (CAMs))	NA	NA	myelin protein zero [Source:HGNC Symbol;Acc:HGNC:7225]	0.44	0.48	0.71	14.34	10.22	39.14	0.1	-3.35	0.02	0.27	down	yes
MSTRG.20637	NCAPG	ENST00000251496;MSTRG.20637.2;ENST00000514176;ENST00000513226;ENST00000509719;ENST00000510063	GO:0000278(mitotic cell cycle);GO:0000793(condensed chromosome);GO:0000796(condensin complex);GO:0005488(binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0007076(mitotic chromosome condensation);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0051301(cell division)	NA	NA	NA	"non-SMC condensin I complex, subunit G [Source:HGNC Symbol;Acc:HGNC:24304]"	0.83	0.7	0.41	20.62	17.38	3.11	0.1	-3.37	0.04	0.33	down	yes
MSTRG.20640	SLIT2	ENST00000503823;ENST00000504154;ENST00000622093;ENST00000273739;ENST00000503837;ENST00000509394;ENST00000511508;ENST00000509941;ENST00000508541	GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0001701(in utero embryonic development);GO:0001933(negative regulation of protein phosphorylation);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0002689(negative regulation of leukocyte chemotaxis);GO:0005095(GTPase inhibitor activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0007420(brain development);GO:0008045(motor neuron axon guidance);GO:0008201(heparin binding);GO:0008285(negative regulation of cell proliferation);GO:0009986(cell surface);GO:0010593(negative regulation of lamellipodium assembly);GO:0010596(negative regulation of endothelial cell migration);GO:0010629(negative regulation of gene expression);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016020(membrane);GO:0016337(single organismal cell-cell adhesion);GO:0021510(spinal cord development);GO:0021772(olfactory bulb development);GO:0021836(chemorepulsion involved in postnatal olfactory bulb interneuron migration);GO:0021972(corticospinal neuron axon guidance through spinal cord);GO:0022029(telencephalon cell migration);GO:0030308(negative regulation of cell growth);GO:0030336(negative regulation of cell migration);GO:0030517(negative regulation of axon extension);GO:0030837(negative regulation of actin filament polymerization);GO:0031290(retinal ganglion cell axon guidance);GO:0031667(response to nutrient levels);GO:0032870(cellular response to hormone stimulus);GO:0033563(dorsal/ventral axon guidance);GO:0034260(negative regulation of GTPase activity);GO:0035385(Roundabout signaling pathway);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043116(negative regulation of vascular permeability);GO:0043237(laminin-1 binding);GO:0043394(proteoglycan binding);GO:0043395(heparan sulfate proteoglycan binding);GO:0045499(chemorepellent activity);GO:0048495(Roundabout binding);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048812(neuron projection morphogenesis);GO:0048846(axon extension involved in axon guidance);GO:0050728(negative regulation of inflammatory response);GO:0050772(positive regulation of axonogenesis);GO:0050919(negative chemotaxis);GO:0050929(induction of negative chemotaxis);GO:0051058(negative regulation of small GTPase mediated signal transduction);GO:0051414(response to cortisol);GO:0060603(mammary gland duct morphogenesis);GO:0060763(mammary duct terminal end bud growth);GO:0061364(apoptotic process involved in luteolysis);GO:0070062(extracellular exosome);GO:0070100(negative regulation of chemokine-mediated signaling pathway);GO:0071504(cellular response to heparin);GO:0071672(negative regulation of smooth muscle cell chemotaxis);GO:0071676(negative regulation of mononuclear cell migration);GO:0090024(negative regulation of neutrophil chemotaxis);GO:0090027(negative regulation of monocyte chemotaxis);GO:0090260(negative regulation of retinal ganglion cell axon guidance);GO:0090288(negative regulation of cellular response to growth factor stimulus)	04360(Axon guidance)	NA	NA	slit homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:11086]	0.61	0.99	1.24	3.72	3.4	1.51	0.41	-1.3	0.03	0.29	down	yes
MSTRG.20670	SEL1L3	ENST00000399878;ENST00000264868;ENST00000513416;ENST00000512286;ENST00000510448;ENST00000507618;ENST00000509290;ENST00000514321;ENST00000513364	GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016021(integral component of membrane)	NA	NA	NA	sel-1 suppressor of lin-12-like 3 (C. elegans) [Source:HGNC Symbol;Acc:HGNC:29108]	9.72	8.62	10.13	0.81	0.72	3.6	5.59	2.48	0.02	0.27	up	yes
MSTRG.20695	KLF3	MSTRG.20695.1;ENST00000261438;ENST00000514033;ENST00000482150	"GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007275(multicellular organismal development);GO:0046872(metal ion binding);GO:1901653(cellular response to peptide)"	NA	NA	NA	Kruppel-like factor 3 (basic) [Source:HGNC Symbol;Acc:HGNC:16516]	11.03	11.53	10.92	2.77	2.35	2.52	3.31	1.73	0	0.08	up	yes
MSTRG.20829	NMU	ENST00000511469;ENST00000264218;ENST00000507338;ENST00000515325	GO:0001696(gastric acid secretion);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006940(regulation of smooth muscle contraction);GO:0007165(signal transduction);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0007586(digestion);GO:0009648(photoperiodism);GO:0019233(sensory perception of pain);GO:0042755(eating behavior);GO:0042922(neuromedin U receptor binding);GO:0043195(terminal bouton);GO:0045987(positive regulation of smooth muscle contraction);GO:0046887(positive regulation of hormone secretion);GO:0050806(positive regulation of synaptic transmission)	NA	NA	NA	neuromedin U [Source:HGNC Symbol;Acc:HGNC:7859]	0.23	0.75	0.26	3.42	3.28	1.62	0.3	-1.74	0.01	0.2	down	yes
MSTRG.20832	KIAA1211	MSTRG.20832.2;MSTRG.20832.3;ENST00000541073;ENST00000504228;ENST00000505410	NA	NA	NA	NA	KIAA1211 [Source:HGNC Symbol;Acc:HGNC:29219]	7.07	9.84	6.93	2.66	2.57	2.33	2.26	1.17	0	0.18	up	yes
MSTRG.20879	RUFY3	ENST00000514898;ENST00000503876;ENST00000417478;ENST00000381006;ENST00000226328;MSTRG.20879.6;ENST00000513597;ENST00000502653;ENST00000504805;ENST00000512103;ENST00000503025;ENST00000512331;ENST00000515479;ENST00000515442	GO:0005515(protein binding);GO:0030175(filopodium);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043025(neuronal cell body);GO:0046872(metal ion binding);GO:0050770(regulation of axonogenesis);GO:0050771(negative regulation of axonogenesis);GO:0050772(positive regulation of axonogenesis)	NA	NA	NA	RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285]	3.35	1.98	2.04	0.85	0.58	0.48	2.25	1.17	0.02	0.27	up	yes
MSTRG.20886	.	MSTRG.20886.1	NA	NA	NA	NA	NA	1.23	0	0.72	0	0	0	2.05	1.03	0.05	0.34	up	yes
MSTRG.20892	CXCL3	ENST00000296026;ENST00000511669;ENST00000502974;ENST00000510390	GO:0002690(positive regulation of leukocyte chemotaxis);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0008009(chemokine activity);GO:0030593(neutrophil chemotaxis);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0045236(CXCR chemokine receptor binding);GO:0070098(chemokine-mediated signaling pathway)	04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)	NA	NA	chemokine (C-X-C motif) ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604]	16.14	11.76	58.49	0.48	0.81	3.6	14.11	3.82	0.04	0.33	up	yes
MSTRG.20904	RCHY1	ENST00000324439;ENST00000380840;ENST00000505105;ENST00000514589;ENST00000512567;ENST00000504085;ENST00000512706;ENST00000513257;ENST00000507014;ENST00000513909;ENST00000505514;ENST00000513083;ENST00000514021	GO:0000151(ubiquitin ligase complex);GO:0002039(p53 binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016607(nuclear speck);GO:0016874(ligase activity);GO:0019985(translesion synthesis);GO:0031398(positive regulation of protein ubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042803(protein homodimerization activity);GO:0051865(protein autoubiquitination);GO:0070987(error-free translesion synthesis)	04115(p53 signaling pathway);04120(Ubiquitin mediated proteolysis);05162(Measles)	NA	NA	"ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:17479]"	5.33	4.6	3.73	1.42	2.27	1.61	2.18	1.13	0.02	0.25	up	yes
MSTRG.20928	CCNG2	ENST00000316355;ENST00000354403;ENST00000502280;ENST00000497512;ENST00000395640;ENST00000512918;ENST00000509972	GO:0000075(cell cycle checkpoint);GO:0005737(cytoplasm);GO:0007067(mitotic nuclear division);GO:0051301(cell division);GO:0051726(regulation of cell cycle)	04115(p53 signaling pathway)	NA	NA	cyclin G2 [Source:HGNC Symbol;Acc:HGNC:1593]	7.37	13.99	13.03	3.82	3.13	4.51	2.11	1.08	0.05	0.34	up	yes
MSTRG.20934	CXCL13	MSTRG.20934.1	NA	NA	NA	NA	NA	1.62	1.06	0.77	0.06	0.17	0	2.14	1.1	0.02	0.25	up	yes
MSTRG.2094	RGS4	ENST00000421743;ENST00000367909;ENST00000531057;ENST00000527809;ENST00000367908;ENST00000491263;ENST00000533019;ENST00000367906;ENST00000528938	GO:0000188(inactivation of MAPK activity);GO:0001965(G-protein alpha-subunit binding);GO:0005096(GTPase activator activity);GO:0005516(calmodulin binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0016020(membrane);GO:0038032(termination of G-protein coupled receptor signaling pathway);GO:0043234(protein complex);GO:0043547(positive regulation of GTPase activity);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway)	NA	NA	NA	regulator of G-protein signaling 4 [Source:HGNC Symbol;Acc:HGNC:10000]	0.12	0.06	0.08	4.79	5.45	2.8	0.19	-2.38	0.01	0.19	down	yes
MSTRG.20954	HNRNPD	ENST00000313899;MSTRG.20954.2;ENST00000514325;ENST00000353341;MSTRG.20954.3;ENST00000514671;ENST00000352301;MSTRG.20954.8;MSTRG.20954.9;MSTRG.20954.10;MSTRG.20954.11;MSTRG.20954.12;MSTRG.20954.14;MSTRG.20954.13;ENST00000508119;ENST00000513584;ENST00000509263;ENST00000507010;ENST00000515432;ENST00000503822;ENST00000509107	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006396(RNA processing);GO:0006401(RNA catabolic process);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030529(ribonucleoprotein complex);GO:0042162(telomeric DNA binding);GO:0042752(regulation of circadian rhythm);GO:0043488(regulation of mRNA stability);GO:0044822(poly(A) RNA binding);GO:0045727(positive regulation of translation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048255(mRNA stabilization);GO:0070062(extracellular exosome);GO:0097167(circadian regulation of translation)"	NA	NA	NA	"heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) [Source:HGNC Symbol;Acc:HGNC:5036]"	20.66	21.03	23.55	64.88	63.47	46.46	0.35	-1.49	0.01	0.19	down	yes
MSTRG.20966	MRPS18C	ENST00000512375;MSTRG.20966.2;ENST00000295491;ENST00000507019;ENST00000507349;ENST00000509970;ENST00000505719;ENST00000505525;ENST00000514581;ENST00000509571	GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005763(mitochondrial small ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0006996(organelle organization);GO:0032543(mitochondrial translation);GO:0070124(mitochondrial translational initiation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)	NA	NA	NA	mitochondrial ribosomal protein S18C [Source:HGNC Symbol;Acc:HGNC:16633]	3.05	4.52	4.33	8.42	8.21	4.32	0.5	-1	0.04	0.31	down	yes
MSTRG.20987	ARHGAP24	ENST00000395184;MSTRG.20987.2;ENST00000503995;ENST00000506421;ENST00000505856;ENST00000509709;ENST00000395183;ENST00000502537;ENST00000503917;ENST00000264343	"GO:0001525(angiogenesis);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0030154(cell differentiation);GO:0035021(negative regulation of Rac protein signal transduction);GO:0035313(wound healing, spreading of epidermal cells);GO:0042995(cell projection);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:1900028(negative regulation of ruffle assembly)"	NA	NA	NA	Rho GTPase activating protein 24 [Source:HGNC Symbol;Acc:HGNC:25361]	3.29	3.53	2.36	0.33	0.55	0.53	2.91	1.54	0.01	0.19	up	yes
MSTRG.21029	.	MSTRG.21029.1;MSTRG.21029.2	NA	NA	NA	NA	NA	1.64	2.27	1.35	0	0	0	2.55	1.35	0	0.19	up	yes
MSTRG.21035	UNC5C	MSTRG.21035.3;ENST00000513796;ENST00000506749;ENST00000504962	GO:0005042(netrin receptor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0007420(brain development);GO:0016021(integral component of membrane);GO:0030334(regulation of cell migration);GO:0033564(anterior/posterior axon guidance);GO:0038007(netrin-activated signaling pathway);GO:0043065(positive regulation of apoptotic process)	04360(Axon guidance)	NA	NA	unc-5 homolog C (C. elegans) [Source:HGNC Symbol;Acc:HGNC:12569]	0.66	0.68	0.37	5.09	3.65	1.97	0.3	-1.74	0.02	0.26	down	yes
MSTRG.21062	H2AFZ	ENST00000511348;ENST00000511203;ENST00000296417;ENST00000511319;ENST00000529158;ENST00000527366	GO:0000786(nucleosome);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005719(nuclear euchromatin);GO:0005720(nuclear heterochromatin);GO:0031490(chromatin DNA binding);GO:0031492(nucleosomal DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0070062(extracellular exosome);GO:0071392(cellular response to estradiol stimulus)	05322(Systemic lupus erythematosus)	NA	NA	"H2A histone family, member Z [Source:HGNC Symbol;Acc:HGNC:4741]"	115.58	125.45	89.88	312.06	346.93	186.46	0.35	-1.5	0.04	0.3	down	yes
MSTRG.21079	MANBA	ENST00000514430;MSTRG.21079.1;ENST00000226578;ENST00000505239;ENST00000508141;ENST00000506478;ENST00000511813;ENST00000507358	"GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004567(beta-mannosidase activity);GO:0005537(mannose binding);GO:0005764(lysosome);GO:0005975(carbohydrate metabolic process);GO:0006464(cellular protein modification process);GO:0043231(intracellular membrane-bounded organelle);GO:0046355(mannan catabolic process)"	00511(Other glycan degradation);04142(Lysosome)	NA	NA	"mannosidase, beta A, lysosomal [Source:HGNC Symbol;Acc:HGNC:6831]"	5.79	5.92	4.43	1.96	1.6	2.49	2.19	1.13	0.02	0.25	up	yes
MSTRG.21086	CISD2	ENST00000273986;ENST00000574446;ENST00000503643	"GO:0000422(mitochondrion degradation);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0010259(multicellular organismal aging);GO:0010506(regulation of autophagy);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042803(protein homodimerization activity);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0051537(2 iron, 2 sulfur cluster binding)"	NA	NA	NA	CDGSH iron sulfur domain 2 [Source:HGNC Symbol;Acc:HGNC:24212]	12.45	13.08	13.26	5.83	4.97	8.55	2.01	1.01	0.04	0.31	up	yes
MSTRG.21123	HADH	ENST00000603302;ENST00000403312;ENST00000309522;ENST00000511742;ENST00000505878;ENST00000626637;ENST00000507260;ENST00000510728;ENST00000515462;ENST00000514776	GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005759(mitochondrial matrix);GO:0006631(fatty acid metabolic process);GO:0006635(fatty acid beta-oxidation);GO:0009725(response to hormone);GO:0014823(response to activity);GO:0016491(oxidoreductase activity);GO:0032868(response to insulin);GO:0042493(response to drug);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0046676(negative regulation of insulin secretion);GO:0055114(oxidation-reduction process);GO:0070403(NAD+ binding)	"00062(Fatty acid elongation in mitochondria);00071(Fatty acid metabolism);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00380(Tryptophan metabolism);00650(Butanoate metabolism);01100(Metabolic pathways)"	NA	NA	hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799]	7.18	7.98	6.3	20.32	21.68	19.93	0.37	-1.45	0	0.15	down	yes
MSTRG.21180	TRAM1L1	ENST00000310754	GO:0005789(endoplasmic reticulum membrane);GO:0015031(protein transport);GO:0016021(integral component of membrane)	NA	NA	NA	translocation associated membrane protein 1-like 1 [Source:HGNC Symbol;Acc:HGNC:28371]	0.51	0.83	0	2.91	2.09	1.74	0.38	-1.4	0.04	0.3	down	yes
MSTRG.21181	SNHG8	ENST00000602414;ENST00000602520;ENST00000602483;ENST00000602819;ENST00000602573	NA	NA	NA	NA	NA	142.86	173.87	89.84	12.11	20.97	28.94	7.64	2.93	0.02	0.25	up	yes
MSTRG.21203	MAD2L1	ENST00000296509;MSTRG.21203.2;ENST00000333047;ENST00000512484;ENST00000504707;ENST00000511295	"GO:0000070(mitotic sister chromatid segregation);GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007093(mitotic cell cycle checkpoint);GO:0007094(mitotic spindle assembly checkpoint);GO:0007264(small GTPase mediated signal transduction);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0042177(negative regulation of protein catabolic process);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043066(negative regulation of apoptotic process);GO:0045930(negative regulation of mitotic cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0051301(cell division);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0060564(negative regulation of APC-Cdc20 complex activity);GO:0072686(mitotic spindle);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint)"	04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)	NA	NA	MAD2 mitotic arrest deficient-like 1 (yeast) [Source:HGNC Symbol;Acc:HGNC:6763]	3.75	5.27	2.87	12.26	12.83	5.67	0.36	-1.48	0.05	0.34	down	yes
MSTRG.2123	FAM78B	ENST00000435676;MSTRG.2123.2;MSTRG.2123.3;MSTRG.2123.1;MSTRG.2123.5;ENST00000456900;ENST00000441649;ENST00000354422;ENST00000338353	NA	NA	NA	NA	"family with sequence similarity 78, member B [Source:HGNC Symbol;Acc:HGNC:13495]"	2.07	1.62	2.38	13.36	6.03	10.61	0.27	-1.86	0.03	0.28	down	yes
MSTRG.21244	LARP1B	ENST00000326639;ENST00000512292;ENST00000508819;ENST00000394288;ENST00000432347;MSTRG.21244.6;MSTRG.21244.7;ENST00000507377;ENST00000507259;ENST00000508648;ENST00000506199;ENST00000503725	GO:0005515(protein binding);GO:0005634(nucleus);GO:0019013(viral nucleocapsid);GO:0030529(ribonucleoprotein complex);GO:0044822(poly(A) RNA binding);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	NA	NA	NA	"La ribonucleoprotein domain family, member 1B [Source:HGNC Symbol;Acc:HGNC:24704]"	3.63	5.05	3.61	1.35	1.3	0.6	2.07	1.05	0.01	0.24	up	yes
MSTRG.21257	PCDH10	MSTRG.21257.1;ENST00000618019;ENST00000264360;ENST00000511112	GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0016020(membrane);GO:0016021(integral component of membrane)	NA	NA	NA	protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404]	0.16	0.2	0.31	2.16	1.08	0.99	0.45	-1.16	0.02	0.25	down	yes
MSTRG.2127	RP11-479J7.2	MSTRG.2127.1;ENST00000425271	NA	NA	NA	NA	NA	0.14	0.13	0	1.8	1.3	2.58	0.4	-1.31	0.02	0.25	down	yes
MSTRG.21288	CLGN	ENST00000414773;ENST00000325617;ENST00000509477	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006457(protein folding);GO:0006461(protein complex assembly);GO:0007338(single fertilization);GO:0007339(binding of sperm to zona pellucida);GO:0016021(integral component of membrane);GO:0044183(protein binding involved in protein folding);GO:0051082(unfolded protein binding)	NA	NA	NA	calmegin [Source:HGNC Symbol;Acc:HGNC:2060]	3.71	4.93	6.31	0.81	0.62	0.17	3.21	1.68	0.01	0.21	up	yes
MSTRG.21350	RP11-164P12.5	MSTRG.21350.1;ENST00000508198;ENST00000503146;ENST00000435205;ENST00000513086;ENST00000505231;ENST00000508664;ENST00000624858	NA	NA	NA	NA	NA	2.08	2.42	1.66	0.51	0.28	0.76	2.03	1.02	0.03	0.28	up	yes
MSTRG.21409	RP11-39C10.1	ENST00000509378	NA	NA	NA	NA	NA	2.21	2.24	1.83	0.22	0.47	0.2	2.41	1.27	0	0.18	up	yes
MSTRG.2141	SFT2D2	ENST00000471981;MSTRG.2141.3;ENST00000630869;ENST00000271375	GO:0003674(molecular_function);GO:0008150(biological_process);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome)	NA	NA	NA	SFT2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25140]	3.72	4.9	4.24	0.68	1.54	0.72	2.58	1.37	0.02	0.26	up	yes
MSTRG.21415	MSMO1	ENST00000261507;ENST00000507013;ENST00000393766;ENST00000504317;ENST00000505270	GO:0000254(C-4 methylsterol oxidase activity);GO:0005506(iron ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006695(cholesterol biosynthetic process);GO:0008202(steroid metabolic process);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0044281(small molecule metabolic process);GO:0055114(oxidation-reduction process)	00100(Steroid biosynthesis);01100(Metabolic pathways)	NA	NA	methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545]	74.45	54.79	33.36	12.44	8.23	6.76	5.21	2.38	0.03	0.28	up	yes
MSTRG.21433	CBR4	ENST00000510042;ENST00000509108;ENST00000306193;MSTRG.21433.4;ENST00000504480;ENST00000504561;ENST00000506808;ENST00000507752	GO:0003955(NAD(P)H dehydrogenase (quinone) activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006633(fatty acid biosynthetic process);GO:0008152(metabolic process);GO:0008753(NADPH dehydrogenase (quinone) activity);GO:0016491(oxidoreductase activity);GO:0044597(daunorubicin metabolic process);GO:0044598(doxorubicin metabolic process);GO:0048038(quinone binding);GO:0051289(protein homotetramerization);GO:0055114(oxidation-reduction process);GO:0070402(NADPH binding)	NA	NA	NA	carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]	1.27	1.66	1.86	4.25	4.47	2.55	0.48	-1.07	0.02	0.27	down	yes
MSTRG.21445	AADAT	ENST00000337664;ENST00000509167;ENST00000515480;ENST00000353187;ENST00000505906;ENST00000510340;ENST00000507375;ENST00000502392;MSTRG.21445.9;MSTRG.21445.10	NA	NA	NA	NA	NA	2.69	2.62	2.63	7.17	7.98	4.87	0.45	-1.14	0.02	0.26	down	yes
MSTRG.2145	SLC19A2	ENST00000236137;MSTRG.2145.1;ENST00000367804;MSTRG.2145.4;MSTRG.2145.5	NA	NA	NA	NA	NA	9.43	3.96	7.97	1.61	4.22	4.03	2.92	1.55	0.01	0.23	up	yes
MSTRG.21475	TENM3	MSTRG.21475.1;ENST00000513201;MSTRG.21475.3;MSTRG.21475.4;ENST00000512480;ENST00000511685;ENST00000510504;MSTRG.21475.8;MSTRG.21475.9;ENST00000406950;ENST00000502950;ENST00000507737	GO:0005515(protein binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007165(signal transduction);GO:0010976(positive regulation of neuron projection development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030424(axon);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0048593(camera-type eye morphogenesis);GO:0097264(self proteolysis)	NA	NA	NA	teneurin transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:29944]	4.97	6.16	6.21	13.73	10.46	6.88	0.49	-1.03	0.03	0.28	down	yes
MSTRG.21513	SNX25	ENST00000504273;MSTRG.21513.4;MSTRG.21513.3;MSTRG.21513.5;MSTRG.21513.6;MSTRG.21513.7;ENST00000264694;MSTRG.21513.9;ENST00000506896;ENST00000512853;ENST00000504959;ENST00000513433	GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0032801(receptor catabolic process);GO:0034713(type I transforming growth factor beta receptor binding);GO:0035091(phosphatidylinositol binding);GO:0038032(termination of G-protein coupled receptor signaling pathway);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation)	NA	NA	NA	sorting nexin 25 [Source:HGNC Symbol;Acc:HGNC:21883]	11.45	13.8	12.92	5.1	4.16	2.87	2.32	1.21	0.01	0.19	up	yes
MSTRG.21516	ANKRD37	MSTRG.21516.1;ENST00000507479;ENST00000507753;ENST00000335174;ENST00000511393;ENST00000511311;ENST00000506424	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm)	NA	NA	NA	ankyrin repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:29593]	3.08	3	4.27	1.12	1.32	1.14	2.02	1.01	0.01	0.24	up	yes
MSTRG.2153	C1orf112	ENST00000498289;ENST00000472795;MSTRG.2153.4;MSTRG.2153.3;ENST00000496973;ENST00000481744;MSTRG.2153.5;ENST00000359326;ENST00000459772;ENST00000286031;ENST00000413811	NA	NA	NA	NA	chromosome 1 open reading frame 112 [Source:HGNC Symbol;Acc:HGNC:25565]	1.91	2.36	1.44	7.31	7.73	3.95	0.35	-1.53	0.02	0.27	down	yes
MSTRG.2154	SELL	ENST00000236147;MSTRG.2154.1;ENST00000463108;ENST00000479657;ENST00000466340	GO:0002020(protease binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007596(blood coagulation);GO:0008201(heparin binding);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0030246(carbohydrate binding);GO:0033198(response to ATP);GO:0034201(response to oleic acid);GO:0042981(regulation of apoptotic process);GO:0043208(glycosphingolipid binding);GO:0050776(regulation of immune response);GO:0050839(cell adhesion molecule binding);GO:0050900(leukocyte migration);GO:0051861(glycolipid binding);GO:0055093(response to hyperoxia);GO:0070543(response to linoleic acid);GO:0090023(positive regulation of neutrophil chemotaxis)	04514(Cell adhesion molecules (CAMs))	NA	NA	selectin L [Source:HGNC Symbol;Acc:HGNC:10720]	0.36	0.35	0.24	1.7	1.57	2.07	0.48	-1.05	0	0.17	down	yes
MSTRG.21546	CEP72	ENST00000264935;MSTRG.21546.2;ENST00000512038;ENST00000499639;ENST00000514507	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006996(organelle organization);GO:0007051(spindle organization);GO:0033566(gamma-tubulin complex localization);GO:0042802(identical protein binding)	NA	NA	NA	centrosomal protein 72kDa [Source:HGNC Symbol;Acc:HGNC:25547]	0.45	0.41	0.59	2.12	2.08	1.41	0.49	-1.02	0.01	0.22	down	yes
MSTRG.21551	TRIP13	ENST00000166345;ENST00000512024;ENST00000508456;ENST00000513435;ENST00000510412;ENST00000508430	GO:0001556(oocyte maturation);GO:0001673(male germ cell nucleus);GO:0003712(transcription cofactor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0006302(double-strand break repair);GO:0006366(transcription from RNA polymerase II promoter);GO:0007130(synaptonemal complex assembly);GO:0007131(reciprocal meiotic recombination);GO:0007141(male meiosis I);GO:0007144(female meiosis I);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0042802(identical protein binding);GO:0048477(oogenesis);GO:1903506(regulation of nucleic acid-templated transcription)	NA	NA	NA	thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307]	4.14	4.4	2.89	28.27	31.45	12.85	0.17	-2.56	0.02	0.26	down	yes
MSTRG.21556	LPCAT1	ENST00000475622;ENST00000283415;MSTRG.21556.3;ENST00000503252;ENST00000514484;ENST00000507282	"GO:0000139(Golgi membrane);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005811(lipid particle);GO:0006644(phospholipid metabolic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0008152(metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0019432(triglyceride biosynthetic process);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0043129(surfactant homeostasis);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0045732(positive regulation of protein catabolic process);GO:0046474(glycerophospholipid biosynthetic process);GO:0047159(1-alkenylglycerophosphocholine O-acyltransferase activity);GO:0047184(1-acylglycerophosphocholine O-acyltransferase activity);GO:0047191(1-alkylglycerophosphocholine O-acyltransferase activity);GO:0047192(1-alkylglycerophosphocholine O-acetyltransferase activity);GO:0060041(retina development in camera-type eye);GO:2001246(negative regulation of phosphatidylcholine biosynthetic process)"	00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);01100(Metabolic pathways)	NA	NA	lysophosphatidylcholine acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25718]	4.12	4.02	4.87	12.85	13.81	15.58	0.37	-1.43	0	0.15	down	yes
MSTRG.21559	.	MSTRG.21559.1	NA	NA	NA	NA	NA	0.5	0.54	0.98	4.58	4.48	3.61	0.3	-1.74	0	0.17	down	yes
MSTRG.21564	IRX2	ENST00000382611;ENST00000302057	"GO:0001656(metanephros development);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0043565(sequence-specific DNA binding);GO:0072086(specification of loop of Henle identity);GO:0072272(proximal/distal pattern formation involved in metanephric nephron development)"	NA	NA	NA	iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14359]	3.93	2.03	2.31	1.06	0.62	1.01	2.27	1.18	0.02	0.27	up	yes
MSTRG.21565	MRPL36	MSTRG.21565.1;ENST00000505059;ENST00000505818;ENST00000508987;ENST00000382647;ENST00000510999	GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0006996(organelle organization);GO:0032543(mitochondrial translation);GO:0042254(ribosome biogenesis);GO:0070124(mitochondrial translational initiation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)	NA	NA	NA	mitochondrial ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:14490]	0.2	0.92	0.61	3.31	1.79	1.66	0.36	-1.46	0	0.13	down	yes
MSTRG.21584	NSUN2	ENST00000264670;MSTRG.21584.1;ENST00000504374;ENST00000505892;MSTRG.21584.4;ENST00000513888;ENST00000506139;ENST00000514127;ENST00000502932;ENST00000507888;ENST00000505264	GO:0000049(tRNA binding);GO:0000239(pachytene);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0007067(mitotic nuclear division);GO:0007286(spermatid development);GO:0008168(methyltransferase activity);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0030488(tRNA methylation);GO:0033313(meiotic cell cycle checkpoint);GO:0033391(chromatoid body);GO:0044822(poly(A) RNA binding);GO:0051301(cell division)	NA	NA	NA	"NOP2/Sun RNA methyltransferase family, member 2 [Source:HGNC Symbol;Acc:HGNC:25994]"	6.15	9.95	14.47	26.98	30.28	16.53	0.33	-1.61	0.04	0.32	down	yes
MSTRG.21589	FASTKD3	ENST00000264669;MSTRG.21589.2;ENST00000513658;ENST00000282110;ENST00000507036;ENST00000513577;ENST00000504695	GO:0004672(protein kinase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0006468(protein phosphorylation);GO:0044822(poly(A) RNA binding);GO:0045333(cellular respiration)	NA	NA	NA	FAST kinase domains 3 [Source:HGNC Symbol;Acc:HGNC:28758]	0.4	1	1.41	5.79	4.96	2.53	0.27	-1.89	0.01	0.23	down	yes
MSTRG.21599	FAM173B	ENST00000280330;ENST00000511437;ENST00000510047;ENST00000504390;ENST00000510052;ENST00000506108;ENST00000508553	GO:0016021(integral component of membrane)	NA	NA	NA	"family with sequence similarity 173, member B [Source:HGNC Symbol;Acc:HGNC:27029]"	1.21	1.53	1.55	4.74	3.4	2.21	0.46	-1.12	0.02	0.25	down	yes
MSTRG.21685	ADAMTS12	ENST00000504830;ENST00000352040;ENST00000504582;ENST00000506952;ENST00000515401;ENST00000509762	GO:0004222(metalloendopeptidase activity);GO:0005515(protein binding);GO:0005578(proteinaceous extracellular matrix);GO:0006508(proteolysis);GO:0007160(cell-matrix adhesion);GO:0008233(peptidase activity);GO:0008270(zinc ion binding);GO:0016477(cell migration);GO:0030167(proteoglycan catabolic process);GO:0031012(extracellular matrix);GO:0032331(negative regulation of chondrocyte differentiation);GO:0050727(regulation of inflammatory response);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0071773(cellular response to BMP stimulus);GO:1901509(regulation of endothelial tube morphogenesis);GO:1902203(negative regulation of hepatocyte growth factor receptor signaling pathway);GO:1902548(negative regulation of cellular response to vascular endothelial growth factor stimulus);GO:2001113(negative regulation of cellular response to hepatocyte growth factor stimulus)	NA	NA	NA	"ADAM metallopeptidase with thrombospondin type 1 motif, 12 [Source:HGNC Symbol;Acc:HGNC:14605]"	0.58	0.65	1.05	2.52	2.06	3.53	0.49	-1.03	0.04	0.31	down	yes
MSTRG.21689	C1QTNF3	ENST00000335606;MSTRG.21689.1;ENST00000382072;ENST00000382079;ENST00000506639;ENST00000382085;ENST00000502637;ENST00000426255;ENST00000515618;ENST00000512079;ENST00000382068;ENST00000382065;ENST00000231338;ENST00000508398;ENST00000513471;ENST00000508434	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005623(cell);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0035356(cellular triglyceride homeostasis);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0045444(fat cell differentiation);GO:0045721(negative regulation of gluconeogenesis);GO:0050715(positive regulation of cytokine secretion);GO:0050728(negative regulation of inflammatory response);GO:0070062(extracellular exosome);GO:0070165(positive regulation of adiponectin secretion);GO:0070206(protein trimerization);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:1900165(negative regulation of interleukin-6 secretion)	NA	NA	NA	C1q and tumor necrosis factor related protein 3 [Source:HGNC Symbol;Acc:HGNC:14326]	1.24	1.28	1.46	9.13	8.12	12.65	0.23	-2.14	0	0.17	down	yes
MSTRG.21711	SKP2	ENST00000274254;ENST00000620197;ENST00000274255;MSTRG.21711.4;ENST00000546211;ENST00000508514;ENST00000509692;ENST00000513263	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000209(protein polyubiquitination);GO:0000278(mitotic cell cycle);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008283(cell proliferation);GO:0016235(aggresome);GO:0019005(SCF ubiquitin ligase complex);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0042802(identical protein binding);GO:0042981(regulation of apoptotic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0051726(regulation of cell cycle);GO:0061630(ubiquitin protein ligase activity);GO:0071460(cellular response to cell-matrix adhesion);GO:1902916(positive regulation of protein polyubiquitination)	04110(Cell cycle);04120(Ubiquitin mediated proteolysis);05200(Pathways in cancer);05222(Small cell lung cancer)	NA	NA	"S-phase kinase-associated protein 2, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:10901]"	2.6	2.49	2	9.53	9.65	5.86	0.34	-1.57	0.01	0.24	down	yes
MSTRG.21725	GDNF	MSTRG.21725.1;ENST00000620847;ENST00000344622;ENST00000326524;ENST00000427982;ENST00000515058;ENST00000510177	GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001755(neural crest cell migration);GO:0001759(organ induction);GO:0001941(postsynaptic membrane organization);GO:0003337(mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007422(peripheral nervous system development);GO:0008083(growth factor activity);GO:0008284(positive regulation of cell proliferation);GO:0008344(adult locomotory behavior);GO:0010468(regulation of gene expression);GO:0021784(postganglionic parasympathetic fiber development);GO:0030432(peristalsis);GO:0031175(neuron projection development);GO:0032770(positive regulation of monooxygenase activity);GO:0033603(positive regulation of dopamine secretion);GO:0042803(protein homodimerization activity);GO:0043066(negative regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045597(positive regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048255(mRNA stabilization);GO:0048484(enteric nervous system development);GO:0048485(sympathetic nervous system development);GO:0051584(regulation of dopamine uptake involved in synaptic transmission);GO:0060676(ureteric bud formation);GO:0060688(regulation of morphogenesis of a branching structure);GO:0072107(positive regulation of ureteric bud formation);GO:0072108(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:2000736(regulation of stem cell differentiation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)	NA	NA	NA	glial cell derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:4232]	3.05	2.93	3.35	9.14	6.64	6.02	0.46	-1.12	0.01	0.23	down	yes
MSTRG.218	CTNNBIP1	MSTRG.218.1;MSTRG.218.2;MSTRG.218.3;MSTRG.218.8;MSTRG.218.4;MSTRG.218.6;MSTRG.218.5;MSTRG.218.7;MSTRG.218.9;MSTRG.218.10;ENST00000377298;ENST00000477264;ENST00000435891;ENST00000361311;MSTRG.218.15;ENST00000464286;MSTRG.218.19;MSTRG.218.18;MSTRG.218.20;MSTRG.218.17;ENST00000377263;MSTRG.218.22;ENST00000400904;ENST00000377258;ENST00000377256	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0002528(regulation of vascular permeability involved in acute inflammatory response);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0008013(beta-catenin binding);GO:0009952(anterior/posterior pattern specification);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030877(beta-catenin destruction complex);GO:0031333(negative regulation of protein complex assembly);GO:0032091(negative regulation of protein binding);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045657(positive regulation of monocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0060633(negative regulation of transcription initiation from RNA polymerase II promoter);GO:0070016(armadillo repeat domain binding);GO:0072201(negative regulation of mesenchymal cell proliferation)	04310(Wnt signaling pathway)	NA	NA	"catenin, beta interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16913]"	13.64	12.71	11.71	25.99	28.95	31.64	0.5	-1.01	0	0.15	down	yes
MSTRG.21818	IL31RA	MSTRG.21818.1;MSTRG.21818.3;MSTRG.21818.2;MSTRG.21818.4;ENST00000396836;ENST00000396834;ENST00000447346;ENST00000359040;ENST00000354961;ENST00000297015;ENST00000490985;ENST00000611895	"GO:0000165(MAPK cascade);GO:0003713(transcription coactivator activity);GO:0004896(cytokine receptor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0006952(defense response);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007259(JAK-STAT cascade);GO:0008284(positive regulation of cell proliferation);GO:0016021(integral component of membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019901(protein kinase binding);GO:0019955(cytokine binding);GO:0030224(monocyte differentiation);GO:0030225(macrophage differentiation);GO:0042517(positive regulation of tyrosine phosphorylation of Stat3 protein);GO:0042523(positive regulation of tyrosine phosphorylation of Stat5 protein);GO:0042592(homeostatic process);GO:0043031(negative regulation of macrophage activation);GO:0043066(negative regulation of apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	interleukin 31 receptor A [Source:HGNC Symbol;Acc:HGNC:18969]	2.68	3.17	4.63	0.57	0.65	0.3	2.68	1.42	0.01	0.24	up	yes
MSTRG.21833	.	MSTRG.21833.1;MSTRG.21833.2	NA	NA	NA	NA	NA	0.1	0.13	0.09	2.94	2.43	4.25	0.28	-1.83	0.01	0.19	down	yes
MSTRG.21834	CTD-2023N9.1	MSTRG.21834.1;MSTRG.21834.2;MSTRG.21834.5;MSTRG.21834.3;MSTRG.21834.4;ENST00000506106	NA	NA	NA	NA	NA	0.49	0.44	0.66	4.6	4.85	5.41	0.27	-1.9	0	0.11	down	yes
MSTRG.21840	PLK2	ENST00000274289;ENST00000502671;ENST00000617412;ENST00000511326;ENST00000503378;ENST00000505244;ENST00000503713;ENST00000510629;ENST00000503115;ENST00000515415;ENST00000509555;ENST00000509422;ENST00000508300;ENST00000514306;ENST00000504196	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000785(chromatin);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005813(centrosome);GO:0005814(centriole);GO:0006468(protein phosphorylation);GO:0007052(mitotic spindle organization);GO:0007093(mitotic cell cycle checkpoint);GO:0007265(Ras protein signal transduction);GO:0007613(memory);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030425(dendrite);GO:0032092(positive regulation of protein binding);GO:0032403(protein complex binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032486(Rap protein signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0046599(regulation of centriole replication);GO:0048167(regulation of synaptic plasticity);GO:0060291(long-term synaptic potentiation);GO:0060292(long term synaptic depression);GO:0061000(negative regulation of dendritic spine development)"	NA	NA	NA	polo-like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699]	13.77	15.84	14.17	56.99	57.47	28.31	0.27	-1.86	0.02	0.26	down	yes
MSTRG.21853	DEPDC1B	ENST00000265036;MSTRG.21853.2;ENST00000453022;ENST00000509006;ENST00000505017;ENST00000512452	GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0016477(cell migration);GO:0030177(positive regulation of Wnt signaling pathway);GO:0035556(intracellular signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction)	NA	NA	NA	DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902]	1.51	1.86	0.99	10.34	10.17	5.39	0.22	-2.19	0.01	0.23	down	yes
MSTRG.21856	ELOVL7	ENST00000508821;ENST00000425382;ENST00000505959;ENST00000507047;ENST00000514809	"GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006633(fatty acid biosynthetic process);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0019367(fatty acid elongation, saturated fatty acid);GO:0019432(triglyceride biosynthetic process);GO:0034626(fatty acid elongation, polyunsaturated fatty acid);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process)"	NA	K10203;K10205;K10244;K10245;K10246;K10247;K10248;K10249;K10250;K15397	2.3.1.199	ELOVL fatty acid elongase 7 [Source:HGNC Symbol;Acc:HGNC:26292]	2.29	4.07	4.6	0.54	0.39	0.21	2.69	1.43	0.01	0.2	up	yes
MSTRG.21859	NDUFAF2	ENST00000296597;MSTRG.21859.2;ENST00000511107;ENST00000502658;ENST00000512623	GO:0005739(mitochondrion);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0022904(respiratory electron transport chain);GO:0045333(cellular respiration);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0072593(reactive oxygen species metabolic process)	NA	NA	NA	"NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:28086]"	36.39	41.67	33.63	10.42	20.59	20.1	2.52	1.33	0.05	0.34	up	yes
MSTRG.21862	SMIM15	MSTRG.21862.1	NA	NA	NA	NA	NA	0.32	1.38	1.22	3.21	2.28	0.69	0.43	-1.21	0.03	0.3	down	yes
MSTRG.21882	CENPK	ENST00000514814;ENST00000396679;ENST00000242872;ENST00000508421;ENST00000510693;ENST00000506282;ENST00000511841;ENST00000505960;ENST00000515497;ENST00000515873;ENST00000510768;ENST00000513951;ENST00000502997;ENST00000510354;ENST00000504508;ENST00000508311	GO:0000278(mitotic cell cycle);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0007264(small GTPase mediated signal transduction);GO:0034080(CENP-A containing nucleosome assembly)	NA	NA	NA	centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479]	0.8	1.1	0.73	4.88	4.71	1.54	0.33	-1.59	0.04	0.33	down	yes
MSTRG.21887	SGTB	ENST00000381007;MSTRG.21887.2;ENST00000506816	GO:0005515(protein binding)	NA	NA	NA	"small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta [Source:HGNC Symbol;Acc:HGNC:23567]"	9.72	12	9.14	2.09	1.66	1.64	3.63	1.86	0	0.12	up	yes
MSTRG.2190	DARS2	MSTRG.2190.1;ENST00000361951;ENST00000471476;ENST00000460076	GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004815(aspartate-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006418(tRNA aminoacylation for protein translation);GO:0010467(gene expression);GO:0016874(ligase activity);GO:0042803(protein homodimerization activity);GO:0043039(tRNA aminoacylation);GO:0050560(aspartate-tRNA(Asn) ligase activity);GO:0070145(mitochondrial asparaginyl-tRNA aminoacylation)	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	"aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]"	3.99	5.55	6.93	17.65	16.8	7.37	0.34	-1.57	0.04	0.32	down	yes
MSTRG.21900	CCNB1	ENST00000256442;ENST00000506572;ENST00000508407;ENST00000505500;ENST00000503507;ENST00000507798;ENST00000513102	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0001556(oocyte maturation);GO:0001701(in utero embryonic development);GO:0001933(negative regulation of protein phosphorylation);GO:0005113(patched binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006461(protein complex assembly);GO:0006468(protein phosphorylation);GO:0007077(mitotic nuclear envelope disassembly);GO:0007080(mitotic metaphase plate congression);GO:0007283(spermatogenesis);GO:0009612(response to mechanical stimulus);GO:0009636(response to toxic substance);GO:0010629(negative regulation of gene expression);GO:0016020(membrane);GO:0016301(kinase activity);GO:0019901(protein kinase binding);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031442(positive regulation of mRNA 3'-end processing);GO:0033129(positive regulation of histone phosphorylation);GO:0035173(histone kinase activity);GO:0042246(tissue regeneration);GO:0042493(response to drug);GO:0043148(mitotic spindle stabilization);GO:0045787(positive regulation of cell cycle);GO:0045931(positive regulation of mitotic cell cycle);GO:0046680(response to DDT);GO:0048146(positive regulation of fibroblast proliferation);GO:0048565(digestive tract development);GO:0051301(cell division);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051726(regulation of cell cycle);GO:0051987(positive regulation of attachment of spindle microtubules to kinetochore);GO:0055015(ventricular cardiac muscle cell development);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060623(regulation of chromosome condensation);GO:0071283(cellular response to iron(III) ion);GO:0071398(cellular response to fatty acid);GO:0071407(cellular response to organic cyclic compound);GO:0071456(cellular response to hypoxia);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:2000775(histone H3-S10 phosphorylation involved in chromosome condensation)	04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04914(Progesterone-mediated oocyte maturation)	NA	NA	cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]	14.17	10.32	6.6	186.91	230.85	66.2	0.07	-3.87	0.02	0.27	down	yes
MSTRG.21903	CENPH	ENST00000283006;ENST00000515001;ENST00000513575;ENST00000514753;ENST00000502689;ENST00000510742	GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0007264(small GTPase mediated signal transduction);GO:0034080(CENP-A containing nucleosome assembly);GO:0043515(kinetochore binding);GO:0051382(kinetochore assembly);GO:0051383(kinetochore organization)	NA	NA	NA	centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268]	5.57	6	3.85	19.35	19.5	10.4	0.31	-1.68	0.03	0.29	down	yes
MSTRG.2193	GAS5	MSTRG.2193.1;MSTRG.2193.2;ENST00000449289;ENST00000414075;ENST00000436285;ENST00000448718;ENST00000456812;ENST00000452197;ENST00000412059;ENST00000450589;ENST00000431268;ENST00000436656;ENST00000430245;ENST00000454813;ENST00000422183;ENST00000422207;ENST00000454068;ENST00000444470;ENST00000434796;ENST00000449589;ENST00000451607;ENST00000422008;ENST00000442067;ENST00000455838;ENST00000416952;ENST00000432536;ENST00000456293;ENST00000443799;ENST00000421068;ENST00000425771;ENST00000458220	NA	NA	NA	NA	NA	333.61	352.16	300.33	18.07	23.25	39.05	14.76	3.88	0	0.16	up	yes
MSTRG.21953	ENC1	ENST00000302351;ENST00000618628;MSTRG.21953.4;ENST00000509284;ENST00000508331;ENST00000509127	GO:0000790(nuclear chromatin);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007275(multicellular organismal development);GO:0007399(nervous system development);GO:0010499(proteasomal ubiquitin-independent protein catabolic process);GO:0010976(positive regulation of neuron projection development);GO:0016363(nuclear matrix);GO:0016567(protein ubiquitination);GO:0017148(negative regulation of translation);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0043025(neuronal cell body)	NA	NA	NA	ectodermal-neural cortex 1 (with BTB domain) [Source:HGNC Symbol;Acc:HGNC:3345]	1.6	2.31	2	28.87	33.15	7.82	0.1	-3.33	0.02	0.27	down	yes
MSTRG.21963	COL4A3BP	ENST00000357457;MSTRG.21963.1;ENST00000604926;ENST00000380494;ENST00000405807;ENST00000508692;ENST00000261415;ENST00000508809	GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0003007(heart morphogenesis);GO:0004672(protein kinase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006665(sphingolipid metabolic process);GO:0006672(ceramide metabolic process);GO:0006936(muscle contraction);GO:0006955(immune response);GO:0007029(endoplasmic reticulum organization);GO:0007165(signal transduction);GO:0008283(cell proliferation);GO:0008289(lipid binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0030148(sphingolipid biosynthetic process);GO:0034976(response to endoplasmic reticulum stress);GO:0035620(ceramide transporter activity);GO:0035621(ER to Golgi ceramide transport);GO:0044281(small molecule metabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0055088(lipid homeostasis);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0070584(mitochondrion morphogenesis);GO:0097001(ceramide binding)	NA	NA	NA	"collagen, type IV, alpha 3 (Goodpasture antigen) binding protein [Source:HGNC Symbol;Acc:HGNC:2205]"	2.27	2.31	2.04	7.97	4.83	4.7	0.42	-1.25	0.02	0.25	down	yes
MSTRG.21982	F2RL2	ENST00000296641;ENST00000504899	GO:0004435(phosphatidylinositol phospholipase C activity);GO:0004930(G-protein coupled receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007596(blood coagulation);GO:0008152(metabolic process);GO:0009611(response to wounding);GO:0015057(thrombin receptor activity);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0030168(platelet activation);GO:0070493(thrombin receptor signaling pathway)	04080(Neuroactive ligand-receptor interaction)	NA	NA	coagulation factor II (thrombin) receptor-like 2 [Source:HGNC Symbol;Acc:HGNC:3539]	2.28	2.91	4.09	0.63	0.33	0.24	2.49	1.32	0.01	0.23	up	yes
MSTRG.21986	F2R	ENST00000319211;ENST00000505600	"GO:0000186(activation of MAPKK activity);GO:0001965(G-protein alpha-subunit binding);GO:0002248(connective tissue replacement involved in inflammatory response wound healing);GO:0003105(negative regulation of glomerular filtration);GO:0004930(G-protein coupled receptor activity);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005901(caveola);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007260(tyrosine phosphorylation of STAT protein);GO:0007262(STAT protein import into nucleus);GO:0007529(establishment of synaptic specificity at neuromuscular junction);GO:0007596(blood coagulation);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0009611(response to wounding);GO:0009653(anatomical structure morphogenesis);GO:0009986(cell surface);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0015057(thrombin receptor activity);GO:0016021(integral component of membrane);GO:0030168(platelet activation);GO:0030193(regulation of blood coagulation);GO:0030194(positive regulation of blood coagulation);GO:0030335(positive regulation of cell migration);GO:0031094(platelet dense tubular network);GO:0031594(neuromuscular junction);GO:0031681(G-protein beta-subunit binding);GO:0032496(response to lipopolysaccharide);GO:0032651(regulation of interleukin-1 beta production);GO:0032967(positive regulation of collagen biosynthetic process);GO:0035025(positive regulation of Rho protein signal transduction);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043410(positive regulation of MAPK cascade);GO:0043524(negative regulation of neuron apoptotic process);GO:0045211(postsynaptic membrane);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045907(positive regulation of vasoconstriction);GO:0045987(positive regulation of smooth muscle contraction);GO:0046427(positive regulation of JAK-STAT cascade);GO:0048873(homeostasis of number of cells within a tissue);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051928(positive regulation of calcium ion transport);GO:0051930(regulation of sensory perception of pain);GO:0060155(platelet dense granule organization);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070493(thrombin receptor signaling pathway);GO:1900134(negative regulation of renin secretion into blood stream);GO:2000484(positive regulation of interleukin-8 secretion);GO:2000778(positive regulation of interleukin-6 secretion)"	04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04144(Endocytosis);04610(Complement and coagulation cascades);04810(Regulation of actin cytoskeleton)	NA	NA	coagulation factor II (thrombin) receptor [Source:HGNC Symbol;Acc:HGNC:3537]	8.81	9.99	10.16	0.34	0.63	0.77	7.02	2.81	0	0.12	up	yes
MSTRG.22016	DMGDH	MSTRG.22016.1	NA	NA	NA	NA	NA	1.61	0.21	1.11	0	0.08	0	2.38	1.25	0.03	0.28	up	yes
MSTRG.22020	JMY	ENST00000396137;ENST00000412001	GO:0003713(transcription coactivator activity);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007050(cell cycle arrest);GO:0030054(cell junction);GO:0031252(cell leading edge);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0043065(positive regulation of apoptotic process);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0070060('de novo' actin filament nucleation);GO:0070358(actin polymerization-dependent cell motility)	NA	NA	NA	"junction mediating and regulatory protein, p53 cofactor [Source:HGNC Symbol;Acc:HGNC:28916]"	4.87	4.22	3.84	0.86	0.56	0.86	3.12	1.64	0	0.15	up	yes
MSTRG.22029	SERINC5	ENST00000509193;ENST00000512972;ENST00000632581;ENST00000507668;ENST00000512721;ENST00000502747;ENST00000513907	GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006658(phosphatidylserine metabolic process);GO:0006665(sphingolipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0015194(L-serine transmembrane transporter activity);GO:0015825(L-serine transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042552(myelination);GO:0043209(myelin sheath);GO:0070062(extracellular exosome);GO:1904219(positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity);GO:1904222(positive regulation of serine C-palmitoyltransferase activity)	NA	NA	NA	serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825]	3.8	4.2	3.04	1.04	0.96	1.38	2.23	1.16	0.01	0.22	up	yes
MSTRG.22038	DHFR	ENST00000439211;ENST00000505337;ENST00000511032;ENST00000504396;ENST00000513048;ENST00000508282;ENST00000513314	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003729(mRNA binding);GO:0004146(dihydrofolate reductase activity);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006545(glycine biosynthetic process);GO:0006730(one-carbon metabolic process);GO:0006766(vitamin metabolic process);GO:0006767(water-soluble vitamin metabolic process);GO:0008144(drug binding);GO:0009165(nucleotide biosynthetic process);GO:0031427(response to methotrexate);GO:0044281(small molecule metabolic process);GO:0046209(nitric oxide metabolic process);GO:0046653(tetrahydrofolate metabolic process);GO:0046654(tetrahydrofolate biosynthetic process);GO:0046655(folic acid metabolic process);GO:0050661(NADP binding);GO:0050999(regulation of nitric-oxide synthase activity);GO:0055114(oxidation-reduction process)	00670(One carbon pool by folate);00790(Folate biosynthesis);01100(Metabolic pathways)	NA	NA	dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861]	1.13	1.89	1.66	28.83	32.85	12.13	0.08	-3.64	0.01	0.19	down	yes
MSTRG.22100	CETN3	ENST00000283122;ENST00000522083;ENST00000518458;ENST00000522565;ENST00000522842	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005813(centrosome);GO:0005814(centriole);GO:0007067(mitotic nuclear division);GO:0007098(centrosome cycle);GO:0008017(microtubule binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0032391(photoreceptor connecting cilium);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0051301(cell division)	NA	NA	NA	"centrin, EF-hand protein, 3 [Source:HGNC Symbol;Acc:HGNC:1868]"	1.16	2.09	1.76	6.4	5.55	2.75	0.35	-1.52	0.01	0.23	down	yes
MSTRG.22112	ARRDC3	ENST00000265138;ENST00000511391;ENST00000505631;ENST00000514284;ENST00000508948;ENST00000503192;ENST00000507075	GO:0001659(temperature homeostasis);GO:0005515(protein binding);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0031651(negative regulation of heat generation);GO:0031699(beta-3 adrenergic receptor binding);GO:0043588(skin development);GO:0044252(negative regulation of multicellular organismal metabolic process);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0060613(fat pad development);GO:0071879(positive regulation of adrenergic receptor signaling pathway);GO:0090327(negative regulation of locomotion involved in locomotory behavior)	NA	NA	NA	arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263]	20.3	25.96	31.98	6.26	4.54	4.56	3.71	1.89	0	0.17	up	yes
MSTRG.2218	PAPPA2	MSTRG.2218.1;ENST00000367661;ENST00000367662;ENST00000493665;ENST00000486075;ENST00000479836	GO:0001558(regulation of cell growth);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005622(intracellular);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0044267(cellular protein metabolic process);GO:0060349(bone morphogenesis);GO:0070062(extracellular exosome)	NA	NA	NA	pappalysin 2 [Source:HGNC Symbol;Acc:HGNC:14615]	0.81	1.57	2.35	0.04	0.03	0	2.12	1.08	0.04	0.32	up	yes
MSTRG.22219	TSLP	ENST00000420978;ENST00000379706	GO:0005125(cytokine activity);GO:0005615(extracellular space)	04060(Cytokine-cytokine receptor interaction);04630(Jak-STAT signaling pathway)	NA	NA	thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743]	1.05	2.22	2	0.1	0.07	0.16	2.15	1.11	0.01	0.24	up	yes
MSTRG.22236	EPB41L4A-AS1	ENST00000413221;ENST00000427306;ENST00000442823;ENST00000508590	NA	NA	NA	NA	NA	17.06	15.93	11.82	3.24	3.91	5.74	3.52	1.82	0.01	0.21	up	yes
MSTRG.22258	TRIM36	ENST00000282369;ENST00000513154;MSTRG.22258.3;ENST00000514154;ENST00000515104;ENST00000510222;ENST00000508894;ENST00000379618;ENST00000511701;ENST00000379617	GO:0001669(acrosomal vesicle);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005856(cytoskeleton);GO:0007340(acrosome reaction);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0046872(metal ion binding);GO:0051726(regulation of cell cycle);GO:0070062(extracellular exosome)	NA	NA	NA	tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280]	3.42	2.92	2.61	0.86	0.76	0.3	2.36	1.24	0.02	0.25	up	yes
MSTRG.22264	FEM1C	ENST00000274457	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination)	NA	NA	NA	fem-1 homolog c (C. elegans) [Source:HGNC Symbol;Acc:HGNC:16933]	3.39	2.11	2.13	0.81	1	2.23	2.01	1.01	0.03	0.28	up	yes
MSTRG.22319	ALDH7A1	ENST00000409134;ENST00000447989;ENST00000553117;ENST00000485852;ENST00000497231;ENST00000476328;ENST00000503281;ENST00000509459;ENST00000433026;ENST00000413020;ENST00000458249;ENST00000510111;ENST00000511266;ENST00000509270;ENST00000479989;ENST00000412186	GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0004043(L-aminoadipate-semialdehyde dehydrogenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006081(cellular aldehyde metabolic process);GO:0006554(lysine catabolic process);GO:0007605(sensory perception of sound);GO:0008152(metabolic process);GO:0008802(betaine-aldehyde dehydrogenase activity);GO:0016491(oxidoreductase activity);GO:0019285(glycine betaine biosynthetic process from choline);GO:0034641(cellular nitrogen compound metabolic process);GO:0044281(small molecule metabolic process);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)	"00010(Glycolysis / Gluconeogenesis);00053(Ascorbate and aldarate metabolism);00071(Fatty acid metabolism);00260(Glycine, serine and threonine metabolism);00280(Valine, leucine and isoleucine degradation);00300(Lysine biosynthesis);00310(Lysine degradation);00330(Arginine and proline metabolism);00340(Histidine metabolism);00380(Tryptophan metabolism);00410(beta-Alanine metabolism);00561(Glycerolipid metabolism);00620(Pyruvate metabolism);00640(Propanoate metabolism);01100(Metabolic pathways)"	NA	NA	"aldehyde dehydrogenase 7 family, member A1 [Source:HGNC Symbol;Acc:HGNC:877]"	9.33	9.78	7.38	22.05	17.77	31.78	0.43	-1.21	0.04	0.33	down	yes
MSTRG.22323	LMNB1	ENST00000460265;MSTRG.22323.2;ENST00000261366;ENST00000504788;ENST00000492190;ENST00000472034;ENST00000395354;ENST00000494185	GO:0005198(structural molecule activity);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005637(nuclear inner membrane);GO:0005638(lamin filament);GO:0005654(nucleoplasm);GO:0005882(intermediate filament);GO:0006915(apoptotic process);GO:0006921(cellular component disassembly involved in execution phase of apoptosis);GO:0012501(programmed cell death);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0031965(nuclear membrane);GO:0043274(phospholipase binding)	NA	NA	NA	lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637]	4.19	3.98	2.42	67.73	73.07	33.79	0.07	-3.84	0.01	0.19	down	yes
MSTRG.22347	P4HA2	MSTRG.22347.1;ENST00000401867;ENST00000379086;ENST00000166534;ENST00000360568;ENST00000379100;ENST00000379104;ENST00000474628;ENST00000506807;ENST00000467587;MSTRG.22347.11;ENST00000417528;ENST00000395164;ENST00000453286;ENST00000428369;ENST00000418055;ENST00000478055;ENST00000416053;ENST00000428841;ENST00000471826;ENST00000481636	"GO:0004656(procollagen-proline 4-dioxygenase activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0009055(electron carrier activity);GO:0016222(procollagen-proline 4-dioxygenase complex);GO:0016491(oxidoreductase activity);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:0019511(peptidyl-proline hydroxylation);GO:0031418(L-ascorbic acid binding);GO:0043231(intracellular membrane-bounded organelle);GO:0055114(oxidation-reduction process)"	00330(Arginine and proline metabolism);01100(Metabolic pathways)	NA	NA	"prolyl 4-hydroxylase, alpha polypeptide II [Source:HGNC Symbol;Acc:HGNC:8547]"	41.28	32.92	32.89	8.7	7.71	11.45	4.1	2.03	0	0.15	up	yes
MSTRG.22356	C5orf56	MSTRG.22356.1;ENST00000378953;ENST00000461203;ENST00000337752;ENST00000378947;ENST00000407797;ENST00000621237;ENST00000464024	NA	NA	NA	NA	chromosome 5 open reading frame 56 [Source:HGNC Symbol;Acc:HGNC:33838]	1.89	1.54	2.33	0.15	0.08	0.21	2.65	1.41	0	0.17	up	yes
MSTRG.22360	IRF1	ENST00000245414;ENST00000472045;ENST00000405885;ENST00000613424;ENST00000437654;ENST00000459982;ENST00000458069;ENST00000463784;ENST00000439555;ENST00000476613;ENST00000493208	"GO:0000790(nuclear chromatin);GO:0000975(regulatory region DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0002819(regulation of adaptive immune response);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0007050(cell cycle arrest);GO:0007596(blood coagulation);GO:0008285(negative regulation of cell proliferation);GO:0010468(regulation of gene expression);GO:0019221(cytokine-mediated signaling pathway);GO:0032481(positive regulation of type I interferon production);GO:0032728(positive regulation of interferon-beta production);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0035458(cellular response to interferon-beta);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045088(regulation of innate immune response);GO:0045590(negative regulation of regulatory T cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051607(defense response to virus);GO:0051726(regulation of cell cycle);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0071260(cellular response to mechanical stimulus);GO:2000564(regulation of CD8-positive, alpha-beta T cell proliferation)"	05160(Hepatitis C)	NA	NA	interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116]	27.4	27.45	69.28	2.39	2.31	1.84	11.23	3.49	0.01	0.23	up	yes
MSTRG.22394	CDKN2AIPNL	ENST00000458198;ENST00000395009	NA	NA	NA	NA	CDKN2A interacting protein N-terminal like [Source:HGNC Symbol;Acc:HGNC:30545]	15.28	4.54	5.27	30.73	41.09	39.45	0.34	-1.54	0.03	0.28	down	yes
MSTRG.22398	SEC24A	ENST00000398844;ENST00000322887;ENST00000513123	GO:0000139(Golgi membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008270(zinc ion binding);GO:0012507(ER to Golgi transport vesicle membrane);GO:0018279(protein N-linked glycosylation via asparagine);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030127(COPII vesicle coat);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0045714(regulation of low-density lipoprotein particle receptor biosynthetic process);GO:0048208(COPII vesicle coating);GO:0048471(perinuclear region of cytoplasm);GO:0050714(positive regulation of protein secretion);GO:0061024(membrane organization);GO:2000189(positive regulation of cholesterol homeostasis)	04141(Protein processing in endoplasmic reticulum)	NA	NA	SEC24 family member A [Source:HGNC Symbol;Acc:HGNC:10703]	13.72	16.4	14.01	4.77	4.65	3.09	2.68	1.42	0	0.17	up	yes
MSTRG.22401	CAMLG	MSTRG.22401.1;ENST00000297156;ENST00000514518	GO:0001881(receptor recycling);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0006952(defense response);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process)	NA	NA	NA	calcium modulating ligand [Source:HGNC Symbol;Acc:HGNC:1471]	39	38.48	29.76	8.8	8.43	14.64	3.64	1.87	0.01	0.23	up	yes
MSTRG.22421	H2AFY	ENST00000511689;MSTRG.22421.2;ENST00000451949;ENST00000512507;MSTRG.22421.3;MSTRG.22421.4;ENST00000304332;ENST00000312469;ENST00000360597;ENST00000511494;ENST00000506671;ENST00000423969;ENST00000505827;ENST00000513268;ENST00000507868;ENST00000508785;ENST00000513210;ENST00000504197;ENST00000508120;ENST00000506532;ENST00000506218;ENST00000508962	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000182(rDNA binding);GO:0000228(nuclear chromosome);GO:0000785(chromatin);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0000793(condensed chromosome);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0001739(sex chromatin);GO:0001740(Barr body);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005721(pericentric heterochromatin);GO:0005730(nucleolus);GO:0006334(nucleosome assembly);GO:0007549(dosage compensation);GO:0010385(double-stranded methylated DNA binding);GO:0016568(chromatin modification);GO:0019216(regulation of lipid metabolic process);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0031490(chromatin DNA binding);GO:0031492(nucleosomal DNA binding);GO:0033128(negative regulation of histone phosphorylation);GO:0035098(ESC/E(Z) complex);GO:0040029(regulation of gene expression, epigenetic);GO:0044212(transcription regulatory region DNA binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045815(positive regulation of gene expression, epigenetic);GO:0046982(protein heterodimerization activity);GO:0051572(negative regulation of histone H3-K4 methylation);GO:0061086(negative regulation of histone H3-K27 methylation);GO:0070062(extracellular exosome);GO:0071169(establishment of protein localization to chromatin);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:1902750(negative regulation of cell cycle G2/M phase transition)"	05322(Systemic lupus erythematosus)	NA	NA	"H2A histone family, member Y [Source:HGNC Symbol;Acc:HGNC:4740]"	7.38	7.34	9.05	19.84	21.71	15.43	0.42	-1.24	0.01	0.23	down	yes
MSTRG.22442	BRD8	ENST00000254900;ENST00000472478;ENST00000441656;ENST00000418329;ENST00000454473;ENST00000230901;ENST00000402931;MSTRG.22442.4;MSTRG.22442.10;ENST00000411594;MSTRG.22442.12;ENST00000512140;MSTRG.22442.14;ENST00000460746;ENST00000489351;ENST00000515014;ENST00000506167;ENST00000511898;ENST00000483805;ENST00000463620;ENST00000453824;ENST00000471892;ENST00000428808;ENST00000432618;ENST00000450756;ENST00000515254;ENST00000430331;ENST00000471437	"GO:0000812(Swr1 complex);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0004887(thyroid hormone receptor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0006325(chromatin organization);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0030522(intracellular receptor signaling pathway);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation)"	NA	NA	NA	bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874]	4.25	5.09	5.19	12.85	13.26	7.8	0.41	-1.27	0.02	0.25	down	yes
MSTRG.22443	KIF20A	ENST00000513276;MSTRG.22443.2;ENST00000394894;ENST00000508792;ENST00000511638;ENST00000503417;ENST00000504621;ENST00000502338	GO:0000278(mitotic cell cycle);GO:0000281(mitotic cytokinesis);GO:0000910(cytokinesis);GO:0000920(cell separation after cytokinesis);GO:0001578(microtubule bundle formation);GO:0003777(microtubule motor activity);GO:0005215(transporter activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005819(spindle);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0016887(ATPase activity);GO:0019901(protein kinase binding);GO:0030496(midbody)	NA	NA	NA	kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787]	1.83	1.24	0.47	85.17	84.19	34.92	0.03	-5.08	0.01	0.19	down	yes
MSTRG.22445	CDC25C	MSTRG.22445.2;MSTRG.22445.1;ENST00000323760;ENST00000348983;ENST00000415130;ENST00000513970;ENST00000514555;ENST00000514017;ENST00000503022;ENST00000510119;ENST00000504831	GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000087(mitotic M phase);GO:0000278(mitotic cell cycle);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006470(protein dephosphorylation);GO:0007067(mitotic nuclear division);GO:0007088(regulation of mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0007283(spermatogenesis);GO:0008283(cell proliferation);GO:0016032(viral process);GO:0019901(protein kinase binding);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0050699(WW domain binding);GO:0051301(cell division);GO:0051726(regulation of cell cycle)	04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)	NA	NA	cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727]	1.17	0.78	0.47	11.8	13.72	6.4	0.15	-2.71	0.01	0.23	down	yes
MSTRG.22487	CYSTM1	ENST00000261811;ENST00000509589;ENST00000509789	GO:0003674(molecular_function);GO:0008150(biological_process);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	NA	NA	NA	cysteine-rich transmembrane module containing 1 [Source:HGNC Symbol;Acc:HGNC:30239]	36.55	29.46	36.48	6.34	4.71	13.98	5.13	2.36	0.02	0.27	up	yes
MSTRG.22492	HBEGF	ENST00000230990;ENST00000482211;ENST00000498452	"GO:0005154(epidermal growth factor receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007517(muscle organ development);GO:0008016(regulation of heart contraction);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0008284(positive regulation of cell proliferation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009986(cell surface);GO:0016477(cell migration);GO:0030307(positive regulation of cell growth);GO:0030335(positive regulation of cell migration);GO:0030666(endocytic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0035313(wound healing, spreading of epidermal cells);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0045087(innate immune response);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0051545(negative regulation of elastin biosynthetic process);GO:0051549(positive regulation of keratinocyte migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0090303(positive regulation of wound healing)"	04012(ErbB signaling pathway);04912(GnRH signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)	NA	NA	heparin-binding EGF-like growth factor [Source:HGNC Symbol;Acc:HGNC:3059]	5.04	3.98	4.92	1.06	1.31	1.23	2.79	1.48	0	0.1	up	yes
MSTRG.22520	PCDHB2	ENST00000194155;ENST00000622947;ENST00000624874;ENST00000625033	GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007268(synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)	NA	NA	NA	protocadherin beta 2 [Source:HGNC Symbol;Acc:HGNC:8687]	1.29	1.53	1.28	8.69	10.8	4.26	0.24	-2.07	0.02	0.26	down	yes
MSTRG.22522	PCDHB6	ENST00000231130;ENST00000543635;ENST00000194152;MSTRG.22522.6;ENST00000231134;ENST00000623915;ENST00000231136	GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007268(synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)	NA	NA	NA	protocadherin beta 6 [Source:HGNC Symbol;Acc:HGNC:8691]	1.05	1.36	0.43	3.81	2.77	2.96	0.42	-1.26	0.03	0.29	down	yes
MSTRG.2253	QSOX1	ENST00000367602;ENST00000392029;ENST00000367600;ENST00000443059	GO:0003756(protein disulfide isomerase activity);GO:0005615(extracellular space);GO:0005623(cell);GO:0005794(Golgi apparatus);GO:0006457(protein folding);GO:0016242(negative regulation of macroautophagy);GO:0016971(flavin-linked sulfhydryl oxidase activity);GO:0016972(thiol oxidase activity);GO:0030173(integral component of Golgi membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0045171(intercellular bridge);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)	NA	NA	NA	quiescin Q6 sulfhydryl oxidase 1 [Source:HGNC Symbol;Acc:HGNC:9756]	38.12	28.32	29.38	15.24	17.31	29.41	2.02	1.02	0.03	0.29	up	yes
MSTRG.22601	STK32A	MSTRG.22601.1;MSTRG.22601.2;ENST00000306304;ENST00000397936;MSTRG.22601.6;MSTRG.22601.5;MSTRG.22601.7;ENST00000503975;ENST00000626951;ENST00000398523;ENST00000503384;ENST00000515832;ENST00000510953	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0046872(metal ion binding);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)"	NA	NA	NA	serine/threonine kinase 32A [Source:HGNC Symbol;Acc:HGNC:28317]	3.64	3.53	3.01	0.06	0.01	0.05	4.25	2.09	0	0.1	up	yes
MSTRG.22604	SPINK1	ENST00000296695;MSTRG.22604.1;ENST00000505722;MSTRG.22604.4;ENST00000510027	GO:0004866(endopeptidase inhibitor activity);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0010466(negative regulation of peptidase activity);GO:0010751(negative regulation of nitric oxide mediated signal transduction);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0060046(regulation of acrosome reaction);GO:0070062(extracellular exosome);GO:0090281(negative regulation of calcium ion import);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:2001256(regulation of store-operated calcium entry)	NA	NA	NA	"serine peptidase inhibitor, Kazal type 1 [Source:HGNC Symbol;Acc:HGNC:11244]"	1.51	1.09	1.46	0.01	0	0	2.47	1.31	0	0.12	up	yes
MSTRG.22631	AFAP1L1	MSTRG.22631.1;ENST00000455574;ENST00000296721;ENST00000522492;ENST00000515000;ENST00000508444;ENST00000513665	GO:0002102(podosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0071437(invadopodium)	NA	NA	NA	actin filament associated protein 1-like 1 [Source:HGNC Symbol;Acc:HGNC:26714]	22.05	11.77	15.46	6.54	6.01	4.99	2.87	1.52	0.02	0.26	up	yes
MSTRG.22642	HMGXB3	MSTRG.22642.1;ENST00000286298;ENST00000433184;ENST00000503336;MSTRG.22642.4;ENST00000503427;MSTRG.22642.8;ENST00000502717;ENST00000514469;ENST00000513318;ENST00000510472	GO:0003677(DNA binding);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0008150(biological_process);GO:0016301(kinase activity);GO:0016310(phosphorylation)	NA	NA	NA	HMG box domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28982]	7.28	7.21	8.11	44.23	28.53	28.89	0.22	-2.18	0	0.17	down	yes
MSTRG.22667	ANXA6	MSTRG.22667.1;ENST00000522664;ENST00000354546;ENST00000523714;ENST00000377751;ENST00000517486;ENST00000519644;ENST00000520054;ENST00000517707;ENST00000517677;ENST00000521749;ENST00000517757;ENST00000520378;ENST00000523164;ENST00000519610	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005739(mitochondrion);GO:0005765(lysosomal membrane);GO:0005925(focal adhesion);GO:0006816(calcium ion transport);GO:0006937(regulation of muscle contraction);GO:0008289(lipid binding);GO:0015276(ligand-gated ion channel activity);GO:0015485(cholesterol binding);GO:0016020(membrane);GO:0031902(late endosome membrane);GO:0034220(ion transmembrane transport);GO:0042470(melanosome);GO:0042803(protein homodimerization activity);GO:0048306(calcium-dependent protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0051260(protein homooligomerization);GO:0051560(mitochondrial calcium ion homeostasis);GO:0070062(extracellular exosome);GO:0097190(apoptotic signaling pathway)	NA	NA	NA	annexin A6 [Source:HGNC Symbol;Acc:HGNC:544]	7.92	7.26	6.17	15.45	15.91	19.45	0.49	-1.02	0.01	0.2	down	yes
MSTRG.2267	IER5	ENST00000367577	NA	NA	NA	NA	immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393]	17.51	10.92	16.97	0	0	0	18.27	4.19	0	0.1	up	yes
MSTRG.2269	RNASEL	ENST00000367559;ENST00000539397	"GO:0003723(RNA binding);GO:0004521(endoribonuclease activity);GO:0004540(ribonuclease activity);GO:0004672(protein kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005575(cellular_component);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0006397(mRNA processing);GO:0006468(protein phosphorylation);GO:0016363(nuclear matrix);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0019221(cytokine-mediated signaling pathway);GO:0019843(rRNA binding);GO:0043021(ribonucleoprotein complex binding);GO:0043488(regulation of mRNA stability);GO:0045071(negative regulation of viral genome replication);GO:0045444(fat cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0055085(transmembrane transport);GO:0060337(type I interferon signaling pathway);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:2001275(positive regulation of glucose import in response to insulin stimulus)"	05160(Hepatitis C);05164(Influenza A)	NA	NA	"ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) [Source:HGNC Symbol;Acc:HGNC:10050]"	1.02	1.16	1.48	3.41	4.02	2.44	0.48	-1.05	0.02	0.27	down	yes
MSTRG.22701	GEMIN5	ENST00000285873;ENST00000522075;ENST00000523355	"GO:0000387(spliceosomal snRNP assembly);GO:0000398(mRNA splicing, via spliceosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006461(protein complex assembly);GO:0010467(gene expression);GO:0016020(membrane);GO:0016604(nuclear body);GO:0017069(snRNA binding);GO:0032797(SMN complex);GO:0034660(ncRNA metabolic process);GO:0034719(SMN-Sm protein complex);GO:0044822(poly(A) RNA binding);GO:0097504(Gemini of coiled bodies)"	03013(RNA transport)	NA	NA	gem (nuclear organelle) associated protein 5 [Source:HGNC Symbol;Acc:HGNC:20043]	3.3	4.28	3.55	8.76	8.41	6.61	0.46	-1.11	0	0.15	down	yes
MSTRG.22735	RNF145	ENST00000519865;ENST00000424310;ENST00000518284;ENST00000611185;ENST00000519985;ENST00000521606;ENST00000518802;ENST00000520638;ENST00000518062;ENST00000521266	GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0016021(integral component of membrane)	NA	NA	NA	ring finger protein 145 [Source:HGNC Symbol;Acc:HGNC:20853]	16.8	17.22	17.66	45.2	37.15	36.19	0.42	-1.25	0	0.14	down	yes
MSTRG.2274	DHX9	MSTRG.2274.1;ENST00000367549;ENST00000483416;ENST00000477802;ENST00000490519;ENST00000474446;ENST00000485081;ENST00000473076	"GO:0000398(mRNA splicing, via spliceosome);GO:0001085(RNA polymerase II transcription factor binding);GO:0001649(osteoblast differentiation);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003724(RNA helicase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006396(RNA processing);GO:0007623(circadian rhythm);GO:0008026(ATP-dependent helicase activity);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0016020(membrane);GO:0030529(ribonucleoprotein complex);GO:0032481(positive regulation of type I interferon production);GO:0032508(DNA duplex unwinding);GO:0034605(cellular response to heat);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex)"	NA	NA	NA	DEAH (Asp-Glu-Ala-His) box helicase 9 [Source:HGNC Symbol;Acc:HGNC:2750]	10.7	10.59	16.44	77.42	75	28.78	0.19	-2.42	0.03	0.29	down	yes
MSTRG.22772	HMMR	ENST00000520345;ENST00000353866;ENST00000393915;ENST00000358715;ENST00000517936	GO:0005515(protein binding);GO:0005540(hyaluronic acid binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0009986(cell surface);GO:0016020(membrane);GO:0030203(glycosaminoglycan metabolic process);GO:0030212(hyaluronan metabolic process);GO:0030214(hyaluronan catabolic process);GO:0044281(small molecule metabolic process)	04512(ECM-receptor interaction)	NA	NA	hyaluronan-mediated motility receptor (RHAMM) [Source:HGNC Symbol;Acc:HGNC:5012]	0.89	0.86	0.53	21.32	17.84	2.86	0.09	-3.41	0.05	0.33	down	yes
MSTRG.22805	DUSP1	ENST00000239223;MSTRG.22805.2;MSTRG.22805.3	NA	NA	NA	NA	NA	30.13	14.67	17.93	1.92	1.77	5.53	8.55	3.1	0	0.19	up	yes
MSTRG.22813	CREBRF	ENST00000522692;ENST00000296953;ENST00000520420;ENST00000520464;ENST00000517882;ENST00000523161	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006810(transport);GO:0006986(response to unfolded protein);GO:0016604(nuclear body);GO:0032388(positive regulation of intracellular transport);GO:0034976(response to endoplasmic reticulum stress);GO:0042711(maternal behavior);GO:0043565(sequence-specific DNA binding);GO:0045732(positive regulation of protein catabolic process);GO:0051222(positive regulation of protein transport);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response);GO:1900170(negative regulation of glucocorticoid mediated signaling pathway);GO:1902213(positive regulation of prolactin signaling pathway)"	NA	NA	NA	CREB3 regulatory factor [Source:HGNC Symbol;Acc:HGNC:24050]	5.14	4.26	3.4	0.42	0.34	0.44	3.96	1.99	0	0.15	up	yes
MSTRG.22816	BNIP1	ENST00000231668;ENST00000351486;ENST00000352523;ENST00000393770;ENST00000519459	GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0006914(autophagy);GO:0006915(apoptotic process);GO:0007029(endoplasmic reticulum organization);GO:0016192(vesicle-mediated transport);GO:0016320(endoplasmic reticulum membrane fusion);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0031201(SNARE complex);GO:0043066(negative regulation of apoptotic process);GO:0043231(intracellular membrane-bounded organelle);GO:0097194(execution phase of apoptosis)	NA	NA	NA	BCL2/adenovirus E1B 19kDa interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1082]	28.9	27.33	23.79	9.06	10.54	8.96	2.71	1.44	0	0.16	up	yes
MSTRG.22846	RNF44	ENST00000274811;MSTRG.22846.2;MSTRG.22846.3;MSTRG.22846.4;MSTRG.22846.5;ENST00000506378;ENST00000513029;ENST00000515051;ENST00000508478;ENST00000504160;ENST00000504434;ENST00000509404	GO:0005515(protein binding);GO:0008270(zinc ion binding)	NA	NA	NA	ring finger protein 44 [Source:HGNC Symbol;Acc:HGNC:19180]	10.69	9.29	8.13	1.36	2.76	5.26	3.66	1.87	0.02	0.27	up	yes
MSTRG.22850	GPRIN1	ENST00000303991	GO:0005886(plasma membrane);GO:0030426(growth cone);GO:0031175(neuron projection development);GO:0051219(phosphoprotein binding)	NA	NA	NA	G protein regulated inducer of neurite outgrowth 1 [Source:HGNC Symbol;Acc:HGNC:24835]	2.69	2.42	3.9	8.16	10.31	6.5	0.42	-1.25	0.03	0.3	down	yes
MSTRG.22891	HNRNPAB	ENST00000358344;ENST00000506339;ENST00000355836;ENST00000514633;ENST00000515193;ENST00000506259;ENST00000504898;ENST00000615932;ENST00000504796	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000166(nucleotide binding);GO:0001837(epithelial to mesenchymal transition);GO:0003676(nucleic acid binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0030529(ribonucleoprotein complex);GO:0043565(sequence-specific DNA binding);GO:0044822(poly(A) RNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090575(RNA polymerase II transcription factor complex)"	NA	NA	NA	heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034]	60.96	61.1	57.53	175.41	220.46	132.03	0.33	-1.59	0.01	0.24	down	yes
MSTRG.22911	SQSTM1	MSTRG.22911.1;ENST00000506042;ENST00000514093;MSTRG.22911.4;ENST00000506690;ENST00000512234;ENST00000422245;ENST00000481335;ENST00000464493;ENST00000389805;ENST00000508284;ENST00000626660;ENST00000453046;ENST00000504627;ENST00000510187;ENST00000360718;ENST00000485412;ENST00000466342	GO:0000407(pre-autophagosomal structure);GO:0000422(mitochondrion degradation);GO:0000932(cytoplasmic mRNA processing body);GO:0001934(positive regulation of protein phosphorylation);GO:0002376(immune system process);GO:0004674(protein serine/threonine kinase activity);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006914(autophagy);GO:0006950(response to stress);GO:0008104(protein localization);GO:0008270(zinc ion binding);GO:0010821(regulation of mitochondrion organization);GO:0016197(endosomal transport);GO:0016234(inclusion body);GO:0016235(aggresome);GO:0016236(macroautophagy);GO:0016239(positive regulation of macroautophagy);GO:0016605(PML body);GO:0019901(protein kinase binding);GO:0030154(cell differentiation);GO:0030971(receptor tyrosine kinase binding);GO:0031410(cytoplasmic vesicle);GO:0035556(intracellular signal transduction);GO:0042169(SH2 domain binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0044130(negative regulation of growth of symbiont in host);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046578(regulation of Ras protein signal transduction);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0051291(protein heterooligomerization);GO:0070062(extracellular exosome);GO:0070530(K63-linked polyubiquitin binding);GO:0097190(apoptotic signaling pathway);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	04380(Osteoclast differentiation)	NA	NA	sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280]	359.1	321.83	316.65	60.21	47.61	53.84	6.11	2.61	0	0.11	up	yes
MSTRG.22926	CTC-573N18.1	ENST00000507681;MSTRG.22926.2	NA	NA	NA	NA	NA	44.78	38.42	60.76	0	0	0	49.96	5.64	0	0.1	up	yes
MSTRG.22945	GNB2L1	ENST00000511473;ENST00000504325;ENST00000514455;ENST00000509148;ENST00000502905;ENST00000507756;ENST00000511566;ENST00000507273;ENST00000509535;ENST00000504128;ENST00000508682;ENST00000376817;ENST00000512805;ENST00000504726;ENST00000511900;ENST00000513060;ENST00000512968;ENST00000510199;ENST00000502844;ENST00000507000;ENST00000514183;ENST00000502548;ENST00000502890;ENST00000503494;ENST00000506312;ENST00000503081;ENST00000508044;ENST00000515417;ENST00000513027;ENST00000626067;ENST00000505461;ENST00000507261;ENST00000508963;ENST00000503170;ENST00000514318	GO:0001891(phagocytic cup);GO:0001934(positive regulation of protein phosphorylation);GO:0005080(protein kinase C binding);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007049(cell cycle);GO:0007369(gastrulation);GO:0008200(ion channel inhibitor activity);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0010629(negative regulation of gene expression);GO:0015935(small ribosomal subunit);GO:0016032(viral process);GO:0017148(negative regulation of translation);GO:0019899(enzyme binding);GO:0019903(protein phosphatase binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0030308(negative regulation of cell growth);GO:0030335(positive regulation of cell migration);GO:0030425(dendrite);GO:0030496(midbody);GO:0030822(positive regulation of cAMP catabolic process);GO:0030971(receptor tyrosine kinase binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032464(positive regulation of protein homooligomerization);GO:0032880(regulation of protein localization);GO:0032947(protein complex scaffold);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0035591(signaling adaptor activity);GO:0042169(SH2 domain binding);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043065(positive regulation of apoptotic process);GO:0043204(perikaryon);GO:0043547(positive regulation of GTPase activity);GO:0044297(cell body);GO:0044822(poly(A) RNA binding);GO:0048471(perinuclear region of cytoplasm);GO:0048511(rhythmic process);GO:0050765(negative regulation of phagocytosis);GO:0051302(regulation of cell division);GO:0051343(positive regulation of cyclic-nucleotide phosphodiesterase activity);GO:0051726(regulation of cell cycle);GO:0051898(negative regulation of protein kinase B signaling);GO:0051901(positive regulation of mitochondrial depolarization);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0070062(extracellular exosome);GO:0071333(cellular response to glucose stimulus);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response);GO:1903208(negative regulation of hydrogen peroxide-induced neuron death);GO:1990630(IRE1-RACK1-PP2A complex);GO:2000114(regulation of establishment of cell polarity);GO:2000543(positive regulation of gastrulation);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)	05162(Measles)	NA	NA	"guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [Source:HGNC Symbol;Acc:HGNC:4399]"	402.38	355.66	408.03	160.17	175.22	310.31	2.29	1.2	0.04	0.32	up	yes
MSTRG.23029	ELOVL2	ENST00000354666;MSTRG.23029.2	NA	NA	NA	NA	NA	1.15	1.08	0.66	7.44	6.24	4.22	0.26	-1.95	0.01	0.21	down	yes
MSTRG.23041	NEDD9	ENST00000379446;ENST00000448183;ENST00000505589;ENST00000379433;ENST00000513989;ENST00000504634;ENST00000461055	GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005819(spindle);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0007010(cytoskeleton organization);GO:0007067(mitotic nuclear division);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007229(integrin-mediated signaling pathway);GO:0030027(lamellipodium);GO:0040008(regulation of growth);GO:0051017(actin filament bundle assembly);GO:0051301(cell division)	NA	NA	NA	"neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733]"	1.12	1.01	0.45	4.02	3.96	2.82	0.37	-1.43	0.02	0.27	down	yes
MSTRG.23055	RANBP9	ENST00000011619;ENST00000469916	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005875(microtubule associated complex);GO:0006461(protein complex assembly);GO:0007020(microtubule nucleation);GO:0007411(axon guidance);GO:0008536(Ran GTPase binding);GO:0019899(enzyme binding);GO:0070373(negative regulation of ERK1 and ERK2 cascade)	NA	NA	NA	RAN binding protein 9 [Source:HGNC Symbol;Acc:HGNC:13727]	28.1	25.91	21.54	11.93	10.42	7.85	2.24	1.17	0.02	0.27	up	yes
MSTRG.2312	HMCN1	MSTRG.2312.1;ENST00000271588;ENST00000485744;ENST00000493413;ENST00000475585;ENST00000414277	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005604(basement membrane);GO:0005938(cell cortex);GO:0007601(visual perception);GO:0030054(cell junction);GO:0031012(extracellular matrix);GO:0050896(response to stimulus);GO:0070062(extracellular exosome)	NA	NA	NA	hemicentin 1 [Source:HGNC Symbol;Acc:HGNC:19194]	2.67	2.79	1.27	8.92	6.1	11.1	0.35	-1.53	0.05	0.34	down	yes
MSTRG.2314	PTGS2	ENST00000367468;MSTRG.2314.1;ENST00000490885;ENST00000466691	"GO:0001516(prostaglandin biosynthetic process);GO:0001525(angiogenesis);GO:0004601(peroxidase activity);GO:0004666(prostaglandin-endoperoxide synthase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0005901(caveola);GO:0006693(prostaglandin metabolic process);GO:0006766(vitamin metabolic process);GO:0006767(water-soluble vitamin metabolic process);GO:0006769(nicotinamide metabolic process);GO:0006928(movement of cell or subcellular component);GO:0006954(inflammatory response);GO:0006979(response to oxidative stress);GO:0007566(embryo implantation);GO:0007612(learning);GO:0007613(memory);GO:0008217(regulation of blood pressure);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0008289(lipid binding);GO:0009314(response to radiation);GO:0009750(response to fructose);GO:0010033(response to organic substance);GO:0010042(response to manganese ion);GO:0010226(response to lithium ion);GO:0010243(response to organonitrogen compound);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0019233(sensory perception of pain);GO:0019369(arachidonic acid metabolic process);GO:0019371(cyclooxygenase pathway);GO:0019372(lipoxygenase pathway);GO:0019674(NAD metabolic process);GO:0019899(enzyme binding);GO:0020037(heme binding);GO:0030282(bone mineralization);GO:0030728(ovulation);GO:0031394(positive regulation of prostaglandin biosynthetic process);GO:0031622(positive regulation of fever generation);GO:0031915(positive regulation of synaptic plasticity);GO:0032227(negative regulation of synaptic transmission, dopaminergic);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0033280(response to vitamin D);GO:0034097(response to cytokine);GO:0034612(response to tumor necrosis factor);GO:0034644(cellular response to UV);GO:0035633(maintenance of blood-brain barrier);GO:0042127(regulation of cell proliferation);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0042493(response to drug);GO:0042633(hair cycle);GO:0042803(protein homodimerization activity);GO:0043005(neuron projection);GO:0043065(positive regulation of apoptotic process);GO:0043234(protein complex);GO:0044281(small molecule metabolic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045786(negative regulation of cell cycle);GO:0045907(positive regulation of vasoconstriction);GO:0045986(negative regulation of smooth muscle contraction);GO:0045987(positive regulation of smooth muscle contraction);GO:0046697(decidualization);GO:0046872(metal ion binding);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050473(arachidonate 15-lipoxygenase activity);GO:0050727(regulation of inflammatory response);GO:0050873(brown fat cell differentiation);GO:0051384(response to glucocorticoid);GO:0051926(negative regulation of calcium ion transport);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0055114(oxidation-reduction process);GO:0070542(response to fatty acid);GO:0071260(cellular response to mechanical stimulus);GO:0071318(cellular response to ATP);GO:0071456(cellular response to hypoxia);GO:0071498(cellular response to fluid shear stress);GO:0071636(positive regulation of transforming growth factor beta production);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0090271(positive regulation of fibroblast growth factor production);GO:0090336(positive regulation of brown fat cell differentiation);GO:0090362(positive regulation of platelet-derived growth factor production)"	00590(Arachidonic acid metabolism);01100(Metabolic pathways);04370(VEGF signaling pathway);05140(Leishmaniasis);05200(Pathways in cancer);05222(Small cell lung cancer)	NA	NA	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [Source:HGNC Symbol;Acc:HGNC:9605]	6.82	6.79	10.4	2.15	1.38	2.18	3	1.59	0.02	0.25	up	yes
MSTRG.23140	HIST1H2BD	MSTRG.23140.1;MSTRG.23140.2;ENST00000377777;ENST00000289316	GO:0000786(nucleosome);GO:0000788(nuclear nucleosome);GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0046982(protein heterodimerization activity);GO:0070062(extracellular exosome)	05322(Systemic lupus erythematosus)	NA	NA	"histone cluster 1, H2bd [Source:HGNC Symbol;Acc:HGNC:4747]"	6.5	1.92	3.26	0.17	0	0.04	5.68	2.51	0.01	0.22	up	yes
MSTRG.23190	GABBR1	ENST00000377050;MSTRG.23190.3;MSTRG.23190.4;ENST00000472823;ENST00000377016;ENST00000377012;ENST00000491829;MSTRG.23190.11;MSTRG.23190.9;MSTRG.23190.10;MSTRG.23190.8;ENST00000377034;MSTRG.23190.14;ENST00000478931;ENST00000494877;ENST00000488334;ENST00000486434;ENST00000376977;ENST00000494634;ENST00000477029;ENST00000485508;ENST00000489385;ENST00000467259;ENST00000462632;ENST00000476670	GO:0004930(G-protein coupled receptor activity);GO:0004965(G-protein coupled GABA receptor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007194(negative regulation of adenylate cyclase activity);GO:0007214(gamma-aminobutyric acid signaling pathway);GO:0007268(synaptic transmission);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0030425(dendrite);GO:0038037(G-protein coupled receptor dimeric complex);GO:0038039(G-protein coupled receptor heterodimeric complex);GO:0042734(presynaptic membrane);GO:0045211(postsynaptic membrane)	04080(Neuroactive ligand-receptor interaction)	NA	NA	"gamma-aminobutyric acid (GABA) B receptor, 1 [Source:HGNC Symbol;Acc:HGNC:4070]"	2.99	2.68	3.29	1	0.62	1.64	2.11	1.08	0.03	0.3	up	yes
MSTRG.23205	HLA-E	ENST00000376630;MSTRG.23205.2;ENST00000484194;ENST00000493699	GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0005515(protein binding);GO:0006955(immune response);GO:0016021(integral component of membrane);GO:0019882(antigen processing and presentation);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex)	04144(Endocytosis);04145(Phagosome);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)	NA	NA	"major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962]"	93.58	85.27	89.77	42.85	44.41	65.32	2.02	1.02	0.02	0.26	up	yes
MSTRG.23210	PPP1R10	ENST00000376511;MSTRG.23210.2;ENST00000496955;ENST00000476704;ENST00000461593;ENST00000468181;ENST00000484449;ENST00000473954	"GO:0000785(chromatin);GO:0003677(DNA binding);GO:0004864(protein phosphatase inhibitor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006606(protein import into nucleus);GO:0043086(negative regulation of catalytic activity);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0072357(PTW/PP1 phosphatase complex)"	NA	NA	NA	"protein phosphatase 1, regulatory subunit 10 [Source:HGNC Symbol;Acc:HGNC:9284]"	0.65	1.32	4.53	23.7	23.59	18.18	0.1	-3.34	0.02	0.26	down	yes
MSTRG.23213	HLA-A	ENST00000396634;ENST00000376806;ENST00000376809;MSTRG.23213.4;MSTRG.23213.5;ENST00000496081;ENST00000376802;ENST00000495183;ENST00000461903;ENST00000479320	"GO:0000139(Golgi membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0009986(cell surface);GO:0012507(ER to Golgi transport vesicle membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016032(viral process);GO:0019221(cytokine-mediated signaling pathway);GO:0019882(antigen processing and presentation);GO:0030670(phagocytic vesicle membrane);GO:0030881(beta-2-microglobulin binding);GO:0031901(early endosome membrane);GO:0042270(protection from natural killer cell mediated cytotoxicity);GO:0042590(antigen processing and presentation of exogenous peptide antigen via MHC class I);GO:0042605(peptide antigen binding);GO:0042612(MHC class I protein complex);GO:0046977(TAP binding);GO:0050776(regulation of immune response);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0070062(extracellular exosome);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)"	04144(Endocytosis);04145(Phagosome);04514(Cell adhesion molecules (CAMs));04612(Antigen processing and presentation);04650(Natural killer cell mediated cytotoxicity);04940(Type I diabetes mellitus);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis)	NA	NA	"major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931]"	248.83	260.34	256.9	117.94	122.6	177.33	2.02	1.01	0.03	0.28	up	yes
MSTRG.23261	TCF19	MSTRG.23261.1;ENST00000376257;ENST00000376255;ENST00000542218	"GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008270(zinc ion binding);GO:0008283(cell proliferation)"	NA	NA	NA	transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629]	1.92	2.99	5.27	10.67	9.84	7.37	0.33	-1.59	0.03	0.29	down	yes
MSTRG.23271	MIR6891	ENST00000618788	NA	NA	NA	NA	NA	3.59	2.59	5.57	0.6	0.17	0.78	3.45	1.79	0.03	0.28	up	yes
MSTRG.23276	HCP5	MSTRG.23276.1;MSTRG.23276.2;MSTRG.23276.3;ENST00000616296;ENST00000414046;ENST00000449934;MSTRG.23276.7;ENST00000421350;ENST00000541196;ENST00000467369	NA	NA	NA	NA	NA	4.49	3.27	2.67	1.29	1.61	1.49	2.03	1.02	0.01	0.24	up	yes
MSTRG.23281	ATP6V1G2	ENST00000474961;ENST00000484566;ENST00000376177;ENST00000462256;ENST00000396172;ENST00000458640;ENST00000376185;MSTRG.23281.3;MSTRG.23281.2;ENST00000462421;ENST00000417023;ENST00000478365;ENST00000482195;ENST00000431908;ENST00000481456;ENST00000427214;ENST00000428098;ENST00000419338;ENST00000456662;ENST00000428450;ENST00000449757;ENST00000456976;ENST00000418897;ENST00000419020;ENST00000480131;ENST00000303892;ENST00000483251;ENST00000415099;ENST00000483170;ENST00000481998	"GO:0005829(cytosol);GO:0006879(cellular iron ion homeostasis);GO:0008286(insulin receptor signaling pathway);GO:0015992(proton transport);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0042470(melanosome);GO:0051701(interaction with host);GO:0055085(transmembrane transport);GO:0090382(phagosome maturation)"	00190(Oxidative phosphorylation);01100(Metabolic pathways);04145(Phagosome);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05323(Rheumatoid arthritis)	NA	NA	"ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]"	16.28	11.72	12.8	31.51	41.12	25.08	0.47	-1.09	0.05	0.33	down	yes
MSTRG.23284	NFKBIL1	ENST00000376146;ENST00000376148;ENST00000376145;ENST00000496233;ENST00000473655	GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032720(negative regulation of tumor necrosis factor production);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0045111(intermediate filament cytoskeleton);GO:0071222(cellular response to lipopolysaccharide)	NA	NA	NA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 [Source:HGNC Symbol;Acc:HGNC:7800]	18.97	21.84	23.57	7.36	7.34	10.92	2.46	1.3	0.02	0.26	up	yes
MSTRG.2329	GLRX2	MSTRG.2329.1;MSTRG.2329.2;ENST00000367439;ENST00000367440;ENST00000472197	"GO:0003756(protein disulfide isomerase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006355(regulation of transcription, DNA-templated);GO:0006457(protein folding);GO:0006749(glutathione metabolic process);GO:0006915(apoptotic process);GO:0007568(aging);GO:0008794(arsenate reductase (glutaredoxin) activity);GO:0009055(electron carrier activity);GO:0009266(response to temperature stimulus);GO:0009966(regulation of signal transduction);GO:0010033(response to organic substance);GO:0015035(protein disulfide oxidoreductase activity);GO:0015038(glutathione disulfide oxidoreductase activity);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0042262(DNA protection);GO:0042542(response to hydrogen peroxide);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0045454(cell redox homeostasis);GO:0046872(metal ion binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051775(response to redox state);GO:0055114(oxidation-reduction process);GO:0071451(cellular response to superoxide)"	NA	NA	NA	glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065]	8.73	9.67	5.98	3.35	3.48	2.32	2.07	1.05	0.04	0.33	up	yes
MSTRG.23309	C6orf48	ENST00000375640;ENST00000375641;ENST00000375635;ENST00000375638;ENST00000375639;ENST00000375642;ENST00000614363;ENST00000395789;ENST00000364953;ENST00000375633;ENST00000395788	NA	NA	NA	NA	chromosome 6 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:19078]	249	246.25	192.95	30.48	37.14	44.16	6.73	2.75	0	0.14	up	yes
MSTRG.23315	FKBPL	ENST00000375156	GO:0000413(protein peptidyl-prolyl isomerization);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005528(FK506 binding);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0009314(response to radiation);GO:0061077(chaperone-mediated protein folding)	NA	NA	NA	FK506 binding protein like [Source:HGNC Symbol;Acc:HGNC:13949]	3.27	2.97	3.17	7.27	11.05	7.63	0.46	-1.12	0.02	0.26	down	yes
MSTRG.23323	DXO	ENST00000491327;ENST00000485557;ENST00000477826;ENST00000337523;MSTRG.23323.5;MSTRG.23323.6;MSTRG.23323.7;ENST00000375349;ENST00000495340;ENST00000473976;ENST00000478221;MSTRG.23323.12;ENST00000375356;ENST00000498357;ENST00000480240;ENST00000474587;ENST00000492946;ENST00000487914;ENST00000460058	GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0003729(mRNA binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006402(mRNA catabolic process);GO:0008152(metabolic process);GO:0008409(5'-3' exonuclease activity);GO:0034353(RNA pyrophosphohydrolase activity);GO:0050779(RNA destabilization);GO:0071028(nuclear mRNA surveillance);GO:0090305(nucleic acid phosphodiester bond hydrolysis)	NA	NA	NA	decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992]	12.05	11.43	13.11	5.96	5	4.8	2.04	1.03	0	0.18	up	yes
MSTRG.23339	HLA-DQB1	ENST00000487676;ENST00000399082;ENST00000399079;ENST00000374943;ENST00000434651;MSTRG.23339.1;ENST00000460185;ENST00000484729;MSTRG.23339.11	NA	NA	NA	NA	NA	8.22	7.3	4.84	1.8	1.49	3.18	2.87	1.52	0.03	0.29	up	yes
MSTRG.23350	TAP1	MSTRG.23350.2;MSTRG.23350.1;ENST00000486332;ENST00000354258;ENST00000487296	"GO:0000166(nucleotide binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005789(endoplasmic reticulum membrane);GO:0006810(transport);GO:0006952(defense response);GO:0008152(metabolic process);GO:0015197(peptide transporter activity);GO:0015440(peptide-transporting ATPase activity);GO:0015833(peptide transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016887(ATPase activity);GO:0019060(intracellular transport of viral protein in host cell);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0023029(MHC class Ib protein binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0042270(protection from natural killer cell mediated cytotoxicity);GO:0042288(MHC class I protein binding);GO:0042590(antigen processing and presentation of exogenous peptide antigen via MHC class I);GO:0042605(peptide antigen binding);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0042803(protein homodimerization activity);GO:0042825(TAP complex);GO:0043231(intracellular membrane-bounded organelle);GO:0043531(ADP binding);GO:0043657(host cell);GO:0046967(cytosol to ER transport);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0046980(tapasin binding);GO:0046982(protein heterodimerization activity);GO:0055085(transmembrane transport)"	02010(ABC transporters);04145(Phagosome);04612(Antigen processing and presentation);05340(Primary immunodeficiency)	NA	NA	"transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [Source:HGNC Symbol;Acc:HGNC:43]"	46.6	28.72	36.86	7.91	8.37	14.43	4.64	2.21	0	0.16	up	yes
MSTRG.23362	SLC39A7	ENST00000444757;MSTRG.23362.1;ENST00000374675;MSTRG.23362.4;ENST00000374677;ENST00000617885;ENST00000463972	GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0006829(zinc II ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030001(metal ion transport);GO:0046873(metal ion transmembrane transporter activity);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 39 (zinc transporter), member 7 [Source:HGNC Symbol;Acc:HGNC:4927]"	151.52	144.46	116.24	66.33	64.45	69.62	2.1	1.07	0.01	0.21	up	yes
MSTRG.23368	KIFC1	MSTRG.23368.1;ENST00000428849;ENST00000450504;ENST00000486695;ENST00000494554	"GO:0000070(mitotic sister chromatid segregation);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005769(early endosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0007080(mitotic metaphase plate congression);GO:0007283(spermatogenesis);GO:0007596(blood coagulation);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0016020(membrane);GO:0051301(cell division);GO:0090307(mitotic spindle assembly)"	NA	NA	NA	kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389]	1.86	1.36	0.83	27.14	29.44	14.11	0.09	-3.43	0.01	0.2	down	yes
MSTRG.23374	PHF1	MSTRG.23374.1;MSTRG.23374.3;MSTRG.23374.4;ENST00000428274;ENST00000374512;ENST00000374516;ENST00000495509;ENST00000488767;ENST00000486845;ENST00000427826;ENST00000479029	"GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016568(chromatin modification);GO:0035064(methylated histone binding);GO:0035098(ESC/E(Z) complex);GO:0035861(site of double-strand break);GO:0040029(regulation of gene expression, epigenetic);GO:0045814(negative regulation of gene expression, epigenetic);GO:0061086(negative regulation of histone H3-K27 methylation);GO:0061087(positive regulation of histone H3-K27 methylation)"	NA	NA	NA	PHD finger protein 1 [Source:HGNC Symbol;Acc:HGNC:8919]	22.4	18.3	15.88	6.38	7.72	4.73	2.81	1.49	0.02	0.26	up	yes
MSTRG.23376	ZBTB9	MSTRG.23376.2;MSTRG.23376.1;ENST00000479510;ENST00000629380;ENST00000449372;ENST00000628646;ENST00000418600;ENST00000293748;ENST00000428982;MSTRG.23376.9;MSTRG.23376.11;ENST00000579078;ENST00000495633;ENST00000470232;ENST00000612775;ENST00000395064	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger and BTB domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28323]	3.79	4.4	3.67	0.84	0.99	1.68	2.44	1.29	0.01	0.24	up	yes
MSTRG.23383	ITPR3	MSTRG.23383.1;ENST00000374316;ENST00000605930;MSTRG.23383.4	NA	NA	NA	NA	NA	27.63	29.27	29.57	10.39	9.21	13.3	2.59	1.37	0.01	0.2	up	yes
MSTRG.23387	HMGA1	MSTRG.23387.1;ENST00000447654;ENST00000311487;ENST00000347617;ENST00000401473;ENST00000478214;ENST00000374116	"GO:0003677(DNA binding);GO:0003680(AT DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0006268(DNA unwinding involved in DNA replication);GO:0006284(base-excision repair);GO:0006337(nucleosome disassembly);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0008134(transcription factor binding);GO:0008285(negative regulation of cell proliferation);GO:0009615(response to virus);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0031936(negative regulation of chromatin silencing);GO:0035985(senescence-associated heterochromatin focus);GO:0035986(senescence-associated heterochromatin focus assembly);GO:0042974(retinoic acid receptor binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046965(retinoid X receptor binding);GO:0051575(5'-deoxyribose-5-phosphate lyase activity);GO:0075713(establishment of integrated proviral latency);GO:0090402(oncogene-induced cell senescence);GO:2000774(positive regulation of cellular senescence)"	NA	NA	NA	high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010]	384.14	331.75	559.32	181.93	209.04	220.39	2.22	1.15	0.04	0.31	up	yes
MSTRG.23390	C6orf1	ENST00000476320;ENST00000481533;ENST00000413013;ENST00000394990;ENST00000335352;ENST00000463083;ENST00000468145;ENST00000495581	GO:0005576(extracellular region)	NA	NA	NA	chromosome 6 open reading frame 1 [Source:HGNC Symbol;Acc:HGNC:1340]	13.3	11.68	12.44	3.39	5	4.73	2.85	1.51	0	0.15	up	yes
MSTRG.23413	MIR7111	ENST00000619751	NA	NA	NA	NA	NA	4.39	1.49	3.28	0.74	1.04	0.77	2.74	1.45	0.02	0.26	up	yes
MSTRG.23423	SRPK1	ENST00000373825;ENST00000361690;ENST00000346162;ENST00000423325;ENST00000373822;ENST00000505885;ENST00000507292;ENST00000502969;ENST00000510290;ENST00000373821;ENST00000508473;ENST00000513367;ENST00000507909	"GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006397(mRNA processing);GO:0006468(protein phosphorylation);GO:0007059(chromosome segregation);GO:0008380(RNA splicing);GO:0016032(viral process);GO:0016363(nuclear matrix);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0035092(sperm chromatin condensation);GO:0035556(intracellular signal transduction);GO:0044822(poly(A) RNA binding);GO:0045070(positive regulation of viral genome replication);GO:0045071(negative regulation of viral genome replication);GO:0045087(innate immune response);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0050684(regulation of mRNA processing)"	NA	NA	NA	SRSF protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:11305]	6.03	7.53	10.22	20.81	15.71	11.66	0.42	-1.24	0.03	0.28	down	yes
MSTRG.23436	KCTD20	ENST00000373731;ENST00000536244;ENST00000483557;ENST00000443316;MSTRG.23436.5;MSTRG.23436.6;ENST00000498267;ENST00000474988;ENST00000481911;ENST00000449081;ENST00000265344;ENST00000460983	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0042327(positive regulation of phosphorylation);GO:0051260(protein homooligomerization)	NA	NA	NA	potassium channel tetramerization domain containing 20 [Source:HGNC Symbol;Acc:HGNC:21052]	5.03	8.55	8.07	14.79	13.15	10.5	0.46	-1.12	0	0.17	down	yes
MSTRG.23438	SRSF3	ENST00000613941;ENST00000620242;ENST00000339436;ENST00000373715;ENST00000477442;ENST00000620941;ENST00000620389;ENST00000614136	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0016607(nuclear speck);GO:0031124(mRNA 3'-end processing);GO:0043274(phospholipase binding);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	serine/arginine-rich splicing factor 3 [Source:HGNC Symbol;Acc:HGNC:10785]	18.09	17.35	16.25	56.54	61	28	0.34	-1.57	0.04	0.33	down	yes
MSTRG.23444	PIM1	ENST00000373509;ENST00000468243;ENST00000479509	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007275(multicellular organismal development);GO:0007346(regulation of mitotic cell cycle);GO:0008134(transcription factor binding);GO:0008283(cell proliferation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030145(manganese ion binding);GO:0030212(hyaluronan metabolic process);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0043024(ribosomal small subunit binding);GO:0043066(negative regulation of apoptotic process);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0046777(protein autophosphorylation);GO:0070561(vitamin D receptor signaling pathway)"	04630(Jak-STAT signaling pathway);05221(Acute myeloid leukemia)	NA	NA	"Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986]"	15.65	35.03	32.7	2	6.08	4.65	5.07	2.34	0.05	0.34	up	yes
MSTRG.23451	ZFAND3	MSTRG.23451.2;MSTRG.23451.1;ENST00000287218;ENST00000373391;ENST00000474522;ENST00000373389;ENST00000469208;ENST00000440482;ENST00000463847	GO:0003677(DNA binding);GO:0008270(zinc ion binding)	NA	NA	NA	"zinc finger, AN1-type domain 3 [Source:HGNC Symbol;Acc:HGNC:18019]"	31.21	29.43	35.73	13.73	11.61	15.08	2.35	1.23	0.01	0.2	up	yes
MSTRG.23468	DAAM2	ENST00000633794;ENST00000274867;ENST00000494405;ENST00000491083;ENST00000475489;ENST00000538976;MSTRG.23468.7;ENST00000398904;ENST00000405961;ENST00000632657;ENST00000631498;ENST00000496787	GO:0003779(actin binding);GO:0005488(binding);GO:0007368(determination of left/right symmetry);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0030036(actin cytoskeleton organization);GO:0070062(extracellular exosome)	04310(Wnt signaling pathway)	NA	NA	dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143]	3.86	4.59	2.58	12.79	8.47	13.68	0.36	-1.49	0.03	0.29	down	yes
MSTRG.2352	KIF14	ENST00000614960;ENST00000367350	"GO:0001558(regulation of cell growth);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0007018(microtubule-based movement);GO:0007080(mitotic metaphase plate congression);GO:0007264(small GTPase mediated signal transduction);GO:0008017(microtubule binding);GO:0008284(positive regulation of cell proliferation);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015631(tubulin binding);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0019901(protein kinase binding);GO:0021685(cerebellar granular layer structural organization);GO:0021693(cerebellar Purkinje cell layer structural organization);GO:0021695(cerebellar cortex development);GO:0021766(hippocampus development);GO:0021772(olfactory bulb development);GO:0021846(cell proliferation in forebrain);GO:0021987(cerebral cortex development);GO:0030155(regulation of cell adhesion);GO:0030165(PDZ domain binding);GO:0030334(regulation of cell migration);GO:0030496(midbody);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031641(regulation of myelination);GO:0032147(activation of protein kinase activity);GO:0032467(positive regulation of cytokinesis);GO:0032487(regulation of Rap protein signal transduction);GO:0033624(negative regulation of integrin activation);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043066(negative regulation of apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043523(regulation of neuron apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045184(establishment of protein localization);GO:0051233(spindle midzone);GO:0051301(cell division);GO:1903047(mitotic cell cycle process);GO:1903429(regulation of cell maturation);GO:2000045(regulation of G1/S transition of mitotic cell cycle)"	NA	NA	NA	kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181]	0.28	0.41	0.2	8.23	6.42	1.16	0.17	-2.58	0.05	0.33	down	yes
MSTRG.23537	GTPBP2	ENST00000496137;MSTRG.23537.1;MSTRG.23537.3;ENST00000307114;ENST00000419497;ENST00000432918;ENST00000476510;ENST00000307126;MSTRG.23537.10;MSTRG.23537.9;ENST00000459959;ENST00000442748;ENST00000480263;ENST00000452781	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0008150(biological_process);GO:0008152(metabolic process);GO:0043231(intracellular membrane-bounded organelle)	NA	NA	NA	GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4670]	24.65	27.58	30.85	6.06	7.77	8.8	3.53	1.82	0	0.18	up	yes
MSTRG.23544	VEGFA	ENST00000476772;ENST00000611736;ENST00000615393;ENST00000617771;ENST00000621747;ENST00000372067;ENST00000324450;ENST00000413642;ENST00000372055;ENST00000482630;ENST00000425836;ENST00000372064;ENST00000372077;ENST00000519767;ENST00000520948;ENST00000518538;ENST00000523873;ENST00000523950;ENST00000512683;ENST00000457104;ENST00000518689;ENST00000518824;ENST00000230480;ENST00000480614;ENST00000520265;ENST00000497139;ENST00000493786	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0001541(ovarian follicle development);GO:0001568(blood vessel development);GO:0001569(patterning of blood vessels);GO:0001570(vasculogenesis);GO:0001666(response to hypoxia);GO:0001701(in utero embryonic development);GO:0001822(kidney development);GO:0001934(positive regulation of protein phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001944(vasculature development);GO:0001946(lymphangiogenesis);GO:0001968(fibronectin binding);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0002052(positive regulation of neuroblast proliferation);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002092(positive regulation of receptor internalization);GO:0002575(basophil chemotaxis);GO:0002576(platelet degranulation);GO:0002687(positive regulation of leukocyte migration);GO:0003007(heart morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003169(coronary vein morphogenesis);GO:0005102(receptor binding);GO:0005125(cytokine activity);GO:0005161(platelet-derived growth factor receptor binding);GO:0005172(vascular endothelial growth factor receptor binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007399(nervous system development);GO:0007498(mesoderm development);GO:0007595(lactation);GO:0007596(blood coagulation);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008360(regulation of cell shape);GO:0009986(cell surface);GO:0010595(positive regulation of endothelial cell migration);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0016477(cell migration);GO:0022408(negative regulation of cell-cell adhesion);GO:0030141(secretory granule);GO:0030168(platelet activation);GO:0030224(monocyte differentiation);GO:0030225(macrophage differentiation);GO:0030324(lung development);GO:0030335(positive regulation of cell migration);GO:0030823(regulation of cGMP metabolic process);GO:0030855(epithelial cell differentiation);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0031077(post-embryonic camera-type eye development);GO:0031093(platelet alpha granule lumen);GO:0031334(positive regulation of protein complex assembly);GO:0031954(positive regulation of protein autophosphorylation);GO:0032147(activation of protein kinase activity);GO:0032793(positive regulation of CREB transcription factor activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035148(tube formation);GO:0035767(endothelial cell chemotaxis);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036303(lymph vessel morphogenesis);GO:0038033(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0038091(positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway);GO:0038190(VEGF-activated neuropilin signaling pathway);GO:0038191(neuropilin binding);GO:0040007(growth);GO:0042056(chemoattractant activity);GO:0042462(eye photoreceptor cell development);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043066(negative regulation of apoptotic process);GO:0043117(positive regulation of vascular permeability);GO:0043129(surfactant homeostasis);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043183(vascular endothelial growth factor receptor 1 binding);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0043406(positive regulation of MAP kinase activity);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0043542(endothelial cell migration);GO:0045601(regulation of endothelial cell differentiation);GO:0045766(positive regulation of angiogenesis);GO:0045785(positive regulation of cell adhesion);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048018(receptor agonist activity);GO:0048469(cell maturation);GO:0048514(blood vessel morphogenesis);GO:0048593(camera-type eye morphogenesis);GO:0048739(cardiac muscle fiber development);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048842(positive regulation of axon extension involved in axon guidance);GO:0048844(artery morphogenesis);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050840(extracellular matrix binding);GO:0050918(positive chemotaxis);GO:0050927(positive regulation of positive chemotaxis);GO:0050930(induction of positive chemotaxis);GO:0051272(positive regulation of cellular component movement);GO:0051781(positive regulation of cell division);GO:0051894(positive regulation of focal adhesion assembly);GO:0060319(primitive erythrocyte differentiation);GO:0060426(lung vasculature development);GO:0060749(mammary gland alveolus development);GO:0060754(positive regulation of mast cell chemotaxis);GO:0060948(cardiac vascular smooth muscle cell development);GO:0060982(coronary artery morphogenesis);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071456(cellular response to hypoxia);GO:0071542(dopaminergic neuron differentiation);GO:0071679(commissural neuron axon guidance);GO:0090037(positive regulation of protein kinase C signaling);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:0090259(regulation of retinal ganglion cell axon guidance);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:1900745(positive regulation of p38MAPK cascade);GO:1901492(positive regulation of lymphangiogenesis);GO:1901532(regulation of hematopoietic progenitor cell differentiation);GO:1901727(positive regulation of histone deacetylase activity);GO:1902336(positive regulation of retinal ganglion cell axon guidance);GO:1902966(positive regulation of protein localization to early endosome);GO:1903572(positive regulation of protein kinase D signaling)	04060(Cytokine-cytokine receptor interaction);04150(mTOR signaling pathway);04370(VEGF signaling pathway);04510(Focal adhesion);05200(Pathways in cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05219(Bladder cancer);05323(Rheumatoid arthritis)	NA	NA	vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680]	17.79	16.81	17.17	1.19	1.53	0.84	8.3	3.05	0	0.11	up	yes
MSTRG.23551	NFKBIE	ENST00000619360;ENST00000275015;ENST00000443607;ENST00000616555;ENST00000477930	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0042942(D-serine transport);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0048471(perinuclear region of cytoplasm)	04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04722(Neurotrophin signaling pathway);04920(Adipocytokine signaling pathway)	NA	NA	"nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon [Source:HGNC Symbol;Acc:HGNC:7799]"	14.77	7.64	13.3	2.99	3.87	7.25	3.35	1.74	0.01	0.21	up	yes
MSTRG.23557	RP11-444E17.6	MSTRG.23557.1	NA	NA	NA	NA	NA	0	2.55	0	6.62	9.84	6.79	0.12	-3.06	0.03	0.28	down	yes
MSTRG.23558	AARS2	ENST00000244571;ENST00000491573	"GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0004813(alanine-tRNA ligase activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006418(tRNA aminoacylation for protein translation);GO:0006419(alanyl-tRNA aminoacylation);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016876(ligase activity, forming aminoacyl-tRNA and related compounds);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0043039(tRNA aminoacylation);GO:0070143(mitochondrial alanyl-tRNA aminoacylation)"	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	"alanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21022]"	1.91	2.24	3.08	4.93	6.69	5.5	0.5	-1	0.03	0.29	down	yes
MSTRG.23582	.	MSTRG.23582.1;MSTRG.23582.2	NA	NA	NA	NA	NA	1.8	1.69	1.73	0.15	0.18	0.53	2.33	1.22	0	0.18	up	yes
MSTRG.23584	FTH1P5	ENST00000425761	NA	NA	NA	NA	NA	1.62	1.76	1.61	0.28	0.23	0.25	2.07	1.05	0	0.08	up	yes
MSTRG.23586	MCM3	ENST00000229854;ENST00000596288;ENST00000419835;ENST00000616552;MSTRG.23586.3;ENST00000421471;ENST00000476448;ENST00000596983	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005658(alpha DNA polymerase:primase complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0016020(membrane);GO:0032508(DNA duplex unwinding);GO:0042555(MCM complex);GO:0043231(intracellular membrane-bounded organelle);GO:0048471(perinuclear region of cytoplasm)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945]	10.97	15.68	15.18	78.1	74.38	65.9	0.17	-2.55	0	0.08	down	yes
MSTRG.23590	TMEM14A	ENST00000211314	GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076]	11.39	9.38	7.34	38.42	37.93	25.69	0.29	-1.78	0.02	0.25	down	yes
MSTRG.23598	ICK	ENST00000350082;MSTRG.23598.2;ENST00000356971	"GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007275(multicellular organismal development);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0035556(intracellular signal transduction);GO:0036064(ciliary basal body);GO:0042073(intraciliary transport);GO:0042384(cilium assembly);GO:0051726(regulation of cell cycle);GO:0097542(ciliary tip)"	NA	NA	NA	intestinal cell (MAK-like) kinase [Source:HGNC Symbol;Acc:HGNC:21219]	2.07	2.95	2.19	13.5	10.08	6.71	0.25	-2.02	0	0.17	down	yes
MSTRG.23599	FBXO9	ENST00000459845;ENST00000370939;ENST00000461222;ENST00000323557;ENST00000473337;ENST00000244426;ENST00000468481;ENST00000480463;ENST00000484812;ENST00000474457;ENST00000484436;ENST00000473318	GO:0000151(ubiquitin ligase complex);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0032006(regulation of TOR signaling);GO:0045087(innate immune response);GO:0045444(fat cell differentiation)	NA	NA	NA	F-box protein 9 [Source:HGNC Symbol;Acc:HGNC:13588]	3.25	3.65	3.93	8.51	7.4	7.23	0.49	-1.03	0	0.13	down	yes
MSTRG.23612	KRASP1	MSTRG.23612.1	NA	NA	NA	NA	NA	1.88	0.48	0.83	0	0	0	2.5	1.32	0.01	0.24	up	yes
MSTRG.23632	PRIM2	ENST00000370687;MSTRG.23632.2;MSTRG.23632.3;ENST00000274891;ENST00000615550;ENST00000419977;ENST00000490313;ENST00000550475	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003896(DNA primase activity);GO:0005654(nucleoplasm);GO:0006269(DNA replication, synthesis of RNA primer);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0032201(telomere maintenance via semi-conservative replication);GO:0046872(metal ion binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:1990077(primosome complex)"	NA	NA	NA	"primase, DNA, polypeptide 2 (58kDa) [Source:HGNC Symbol;Acc:HGNC:9370]"	1.54	3.2	2.93	9.66	7.55	4.34	0.31	-1.69	0	0.19	down	yes
MSTRG.23638	XXbac-BPG55C20.7	MSTRG.23638.1;MSTRG.23638.2;ENST00000420759	NA	NA	NA	NA	NA	0.06	0.45	0.57	1.72	1.3	1.58	0.46	-1.11	0.01	0.23	down	yes
MSTRG.2364	RP11-134G8.5	MSTRG.2364.1;MSTRG.2364.2;ENST00000454651;MSTRG.2364.4;MSTRG.2364.5;MSTRG.2364.6;ENST00000441932	NA	NA	NA	NA	NA	3.05	4.73	5.83	1.05	0.78	1.49	2.37	1.24	0.04	0.32	up	yes
MSTRG.23664	SMAP1	ENST00000316999;ENST00000370452;ENST00000370455;MSTRG.23664.4;MSTRG.23664.5;ENST00000619054;ENST00000445046	GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0030276(clathrin binding);GO:0043547(positive regulation of GTPase activity);GO:0045648(positive regulation of erythrocyte differentiation);GO:0046872(metal ion binding);GO:2000369(regulation of clathrin-mediated endocytosis)	04144(Endocytosis)	NA	NA	small ArfGAP 1 [Source:HGNC Symbol;Acc:HGNC:19651]	11.54	10.21	8.64	4.26	3.31	2.3	2.45	1.29	0.02	0.28	up	yes
MSTRG.23696	EEF1A1	ENST00000316292;ENST00000610520;ENST00000615060;ENST00000491404;ENST00000309268;ENST00000490569;ENST00000331523;ENST00000495333;ENST00000488500;ENST00000356303;ENST00000455918	"GO:0000049(tRNA binding);GO:0003746(translation elongation factor activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006412(translation);GO:0006414(translational elongation);GO:0008152(metabolic process);GO:0010467(gene expression);GO:0016020(membrane);GO:0019901(protein kinase binding);GO:0030864(cortical actin cytoskeleton);GO:0032587(ruffle membrane);GO:0043209(myelin sheath);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome);GO:0071364(cellular response to epidermal growth factor stimulus)"	NA	NA	NA	eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]	2724.43	2815.1	2852.39	1244.57	1306.29	1293.97	2.18	1.12	0	0.08	up	yes
MSTRG.23697	EEF1A1	MSTRG.23697.1;MSTRG.23697.2;MSTRG.23697.3;MSTRG.23697.4;MSTRG.23697.5	NA	NA	NA	NA	NA	1.75	0.12	1.27	0.03	0.1	0.17	2.41	1.27	0.03	0.3	up	yes
MSTRG.2372	IPO9	ENST00000361565;MSTRG.2372.2;ENST00000464348;MSTRG.2372.4;MSTRG.2372.5;ENST00000479374;ENST00000456707	GO:0005488(binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006606(protein import into nucleus);GO:0006886(intracellular protein transport);GO:0008536(Ran GTPase binding);GO:0008565(protein transporter activity);GO:0016020(membrane);GO:0042393(histone binding)	NA	NA	NA	importin 9 [Source:HGNC Symbol;Acc:HGNC:19425]	5.1	6.3	6.48	14.01	16.63	11.41	0.42	-1.25	0.01	0.22	down	yes
MSTRG.23736	BCKDHB	ENST00000369760;ENST00000356489;ENST00000320393;ENST00000486968;ENST00000491328	GO:0003824(catalytic activity);GO:0003826(alpha-ketoacid dehydrogenase activity);GO:0003863(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005947(mitochondrial alpha-ketoglutarate dehydrogenase complex);GO:0008152(metabolic process);GO:0009083(branched-chain amino acid catabolic process);GO:0016831(carboxy-lyase activity);GO:0034641(cellular nitrogen compound metabolic process);GO:0044281(small molecule metabolic process);GO:0055114(oxidation-reduction process)	"00280(Valine, leucine and isoleucine degradation);01100(Metabolic pathways)"	NA	NA	"branched chain keto acid dehydrogenase E1, beta polypeptide [Source:HGNC Symbol;Acc:HGNC:987]"	1.11	1.39	1.36	4.84	4.06	3.71	0.4	-1.34	0	0.1	down	yes
MSTRG.2375	RP11-307B6.3	MSTRG.2375.1;MSTRG.2375.3;MSTRG.2375.4;MSTRG.2375.2;MSTRG.2375.5;ENST00000464117;MSTRG.2375.7;ENST00000362011;ENST00000481699;ENST00000414927;ENST00000458139	NA	NA	NA	NA	NA	9.04	6.03	5.68	2.4	2.44	5.19	2.45	1.29	0.03	0.28	up	yes
MSTRG.23761	MRAP2	ENST00000257776	GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006112(energy reserve metabolic process);GO:0007631(feeding behavior);GO:0016021(integral component of membrane);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031780(corticotropin hormone receptor binding);GO:0031781(type 3 melanocortin receptor binding);GO:0031782(type 4 melanocortin receptor binding);GO:0031783(type 5 melanocortin receptor binding);GO:0034394(protein localization to cell surface);GO:0042802(identical protein binding);GO:0070996(type 1 melanocortin receptor binding);GO:0097009(energy homeostasis)	NA	NA	NA	melanocortin 2 receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:21232]	0.59	0.56	0.19	2.63	2.5	4.07	0.39	-1.35	0.02	0.26	down	yes
MSTRG.23769	SNHG5	ENST00000623163;ENST00000623901;ENST00000589187;MSTRG.23769.4;ENST00000622963;ENST00000623650;ENST00000624128;ENST00000587692;ENST00000369605;MSTRG.23769.10;ENST00000427501;ENST00000435947;ENST00000624295;ENST00000625175;ENST00000623910;ENST00000428833;ENST00000453754;ENST00000420199;ENST00000414002;ENST00000623001;ENST00000431043;ENST00000433843;ENST00000425170	NA	NA	NA	NA	NA	154.99	149.16	140.64	46.98	54.44	54.11	2.99	1.58	0	0.1	up	yes
MSTRG.23785	PNRC1	ENST00000369472;ENST00000336032;MSTRG.23785.3;ENST00000354922	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)"	NA	NA	NA	proline-rich nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:17278]	53.06	42.72	97.61	6.2	2.22	3.42	11.8	3.56	0.01	0.24	up	yes
MSTRG.23789	UBE2J1	ENST00000435041	"GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0007286(spermatid development);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0042534(regulation of tumor necrosis factor biosynthetic process);GO:0061630(ubiquitin protein ligase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol)"	04120(Ubiquitin mediated proteolysis);04141(Protein processing in endoplasmic reticulum);05012(Parkinson's disease)	NA	NA	"ubiquitin-conjugating enzyme E2, J1 [Source:HGNC Symbol;Acc:HGNC:17598]"	11.85	30.06	27.47	6.23	5.91	4.43	2.37	1.24	0.03	0.28	up	yes
MSTRG.23790	RRAGD	ENST00000369415;ENST00000359203;ENST00000492783	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0008152(metabolic process);GO:0009267(cellular response to starvation);GO:0010506(regulation of autophagy);GO:0032008(positive regulation of TOR signaling);GO:0034448(EGO complex);GO:0034613(cellular protein localization);GO:0046982(protein heterodimerization activity);GO:0071230(cellular response to amino acid stimulus);GO:1990131(Gtr1-Gtr2 GTPase complex)	NA	NA	NA	Ras-related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]	35.02	34.99	18.07	5.51	3.15	8.16	5.03	2.33	0.04	0.31	up	yes
MSTRG.23797	MDN1	MSTRG.23797.1;MSTRG.23797.2	NA	NA	NA	NA	NA	4.89	3.49	2.14	0	0.14	0.22	4.6	2.2	0.01	0.2	up	yes
MSTRG.2384	ARL8A	ENST00000272217;ENST00000614750;ENST00000491358;ENST00000486225	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0006886(intracellular protein transport);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0030496(midbody);GO:0031902(late endosome membrane);GO:0043014(alpha-tubulin binding);GO:0048487(beta-tubulin binding);GO:0051233(spindle midzone);GO:0051301(cell division);GO:0070062(extracellular exosome)	NA	NA	NA	ADP-ribosylation factor-like 8A [Source:HGNC Symbol;Acc:HGNC:25192]	28.02	26.58	27.88	12.38	14.2	15.82	2.04	1.03	0	0.15	up	yes
MSTRG.23847	RTN4IP1	ENST00000369063;ENST00000498091	GO:0005739(mitochondrion);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)	NA	NA	NA	reticulon 4 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18647]	0.56	1.02	1.05	3.57	2.96	3.53	0.38	-1.39	0	0.17	down	yes
MSTRG.2385	UBE2T	ENST00000367274;ENST00000487227;ENST00000460852	GO:0003682(chromatin binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0016874(ligase activity);GO:0031625(ubiquitin protein ligase binding);GO:0035519(protein K29-linked ubiquitination);GO:0044314(protein K27-linked ubiquitination);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0085020(protein K6-linked ubiquitination)	NA	NA	NA	ubiquitin-conjugating enzyme E2T [Source:HGNC Symbol;Acc:HGNC:25009]	8.39	10.36	8.01	75.94	79.75	53.02	0.12	-3.02	0	0.13	down	yes
MSTRG.23895	.	MSTRG.23895.1;MSTRG.23895.2	NA	NA	NA	NA	NA	0.13	0.17	0.23	2.57	2.02	2.59	0.34	-1.55	0	0.14	down	yes
MSTRG.23998	HINT3	ENST00000229633	GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0070062(extracellular exosome)	NA	NA	NA	histidine triad nucleotide binding protein 3 [Source:HGNC Symbol;Acc:HGNC:18468]	6.88	8.13	5.57	2.62	2.45	1.65	2.16	1.11	0.02	0.25	up	yes
MSTRG.24021	RPS12	ENST00000230050;ENST00000484616	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003735(structural constituent of ribosome);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005840(ribosome);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022627(cytosolic small ribosomal subunit);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10385]	842.48	847.49	822.13	311.81	412.05	535.81	2.34	1.23	0.02	0.26	up	yes
MSTRG.24039	SGK1	ENST00000367858;ENST00000474427;ENST00000413996;ENST00000477460;ENST00000237305;ENST00000367855;ENST00000367857;ENST00000528577;ENST00000475719;ENST00000531782;ENST00000525877;ENST00000524764;ENST00000475882;ENST00000534658;ENST00000490149;ENST00000532021;ENST00000532856;ENST00000530421;ENST00000525700;ENST00000472859	"GO:0001558(regulation of cell growth);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005246(calcium channel regulator activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0006814(sodium ion transport);GO:0006915(apoptotic process);GO:0006950(response to stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007616(long-term memory);GO:0008217(regulation of blood pressure);GO:0015459(potassium channel regulator activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0017080(sodium channel regulator activity);GO:0017081(chloride channel regulator activity);GO:0030334(regulation of cell migration);GO:0032411(positive regulation of transporter activity);GO:0034220(ion transmembrane transport);GO:0035091(phosphatidylinositol binding);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0050790(regulation of catalytic activity);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0055085(transmembrane transport);GO:0060453(regulation of gastric acid secretion);GO:0070294(renal sodium ion absorption)"	04960(Aldosterone-regulated sodium reabsorption)	NA	NA	serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]	0.69	1.12	0.74	4.26	3.78	3.27	0.3	-1.72	0	0.1	down	yes
MSTRG.24057	TNFAIP3	ENST00000612899;ENST00000421450;MSTRG.24057.3;MSTRG.24057.4;ENST00000420009;ENST00000237289;ENST00000433680;MSTRG.24057.8;ENST00000614035;ENST00000621150;ENST00000619035;ENST00000620204;ENST00000485192	"GO:0001922(B-1 B cell homeostasis);GO:0002020(protease binding);GO:0002237(response to molecule of bacterial origin);GO:0002634(regulation of germinal center formation);GO:0002677(negative regulation of chronic inflammatory response);GO:0003677(DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0004843(ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0008270(zinc ion binding);GO:0016579(protein deubiquitination);GO:0016874(ligase activity);GO:0019900(kinase binding);GO:0031397(negative regulation of protein ubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032480(negative regulation of type I interferon production);GO:0032495(response to muramyl dipeptide);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032703(negative regulation of interleukin-2 production);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0034136(negative regulation of toll-like receptor 2 signaling pathway);GO:0034140(negative regulation of toll-like receptor 3 signaling pathway);GO:0034144(negative regulation of toll-like receptor 4 signaling pathway);GO:0034148(negative regulation of toll-like receptor 5 signaling pathway);GO:0035871(protein K11-linked deubiquitination);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0043621(protein self-association);GO:0045087(innate immune response);GO:0045732(positive regulation of protein catabolic process);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045779(negative regulation of bone resorption);GO:0045824(negative regulation of innate immune response);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050691(regulation of defense response to virus by host);GO:0050728(negative regulation of inflammatory response);GO:0050869(negative regulation of B cell activation);GO:0051259(protein oligomerization);GO:0060548(negative regulation of cell death);GO:0061043(regulation of vascular wound healing);GO:0070062(extracellular exosome);GO:0070301(cellular response to hydrogen peroxide);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0070429(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070433(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0070536(protein K63-linked deubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0071222(cellular response to lipopolysaccharide);GO:0072573(tolerance induction to lipopolysaccharide);GO:0072666(establishment of protein localization to vacuole);GO:0090291(negative regulation of osteoclast proliferation);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1903364(positive regulation of cellular protein catabolic process);GO:2000347(positive regulation of hepatocyte proliferation);GO:2000349(negative regulation of CD40 signaling pathway);GO:2000352(negative regulation of endothelial cell apoptotic process)"	04621(NOD-like receptor signaling pathway);05162(Measles)	NA	NA	"tumor necrosis factor, alpha-induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896]"	12.22	9.41	33.81	0.64	0.61	2.08	10.12	3.34	0.03	0.29	up	yes
MSTRG.24077	HECA	ENST00000367658	GO:0003674(molecular_function);GO:0016020(membrane);GO:0030323(respiratory tube development)	NA	NA	NA	headcase homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:21041]	5.14	5.04	3.49	1.74	1.24	1.21	2.21	1.14	0.02	0.26	up	yes
MSTRG.24120	RAB32	ENST00000367495	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005769(early endosome);GO:0005802(trans-Golgi network);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0019882(antigen processing and presentation);GO:0030670(phagocytic vesicle membrane);GO:0030742(GTP-dependent protein binding);GO:0032482(Rab protein signal transduction);GO:0035646(endosome to melanosome transport);GO:0035650(AP-1 adaptor complex binding);GO:0035651(AP-3 adaptor complex binding);GO:0036461(BLOC-2 complex binding);GO:0042470(melanosome);GO:0045335(phagocytic vesicle);GO:0090382(phagosome maturation);GO:1903232(melanosome assembly)	NA	NA	NA	"RAB32, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9772]"	14.79	8.27	17.29	3.14	3.97	3.05	3.77	1.91	0.02	0.25	up	yes
MSTRG.24206	CNKSR3	ENST00000265198;ENST00000607772;ENST00000433165;ENST00000479339;MSTRG.24206.18;ENST00000424998;ENST00000454664	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0009966(regulation of signal transduction);GO:0010765(positive regulation of sodium ion transport);GO:0016020(membrane);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:2000651(positive regulation of sodium ion transmembrane transporter activity)	NA	NA	NA	CNKSR family member 3 [Source:HGNC Symbol;Acc:HGNC:23034]	1.83	1.35	1.92	0.29	0.38	0.45	2.2	1.13	0	0.14	up	yes
MSTRG.24245	TMEM181	ENST00000367090;MSTRG.24245.2;MSTRG.24245.3;MSTRG.24245.4	NA	NA	NA	NA	NA	1.96	2.74	3.87	8.64	6.12	6.02	0.4	-1.32	0.02	0.25	down	yes
MSTRG.24278	RP1-167A14.2	ENST00000265678;ENST00000510118;ENST00000509742;ENST00000491836;ENST00000366865;ENST00000507350;ENST00000512860;ENST00000507371;ENST00000511034;ENST00000508775;ENST00000421787;ENST00000510083;ENST00000620173;MSTRG.24278.20;ENST00000028008;ENST00000478180;ENST00000467705;ENST00000499370;ENST00000358165;ENST00000496851;ENST00000509073;ENST00000444102	NA	NA	NA	NA	NA	2.5	2.37	3.27	0.3	0.35	0.68	2.8	1.48	0.01	0.19	up	yes
MSTRG.24281	FAM103A2P	ENST00000444122	NA	NA	NA	NA	NA	15.25	10.25	10.37	0	0.88	0	12.18	3.61	0	0.18	up	yes
MSTRG.24308	FAM20C	MSTRG.24308.1;ENST00000313766;ENST00000477004;ENST00000471328;ENST00000515795;ENST00000512382	GO:0001501(skeletal system development);GO:0004674(protein serine/threonine kinase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0006468(protein phosphorylation);GO:0030501(positive regulation of bone mineralization);GO:0036179(osteoclast maturation);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0045669(positive regulation of osteoblast differentiation);GO:0051174(regulation of phosphorus metabolic process);GO:0070062(extracellular exosome);GO:0070166(enamel mineralization);GO:0071895(odontoblast differentiation);GO:0097187(dentinogenesis)	NA	NA	NA	"family with sequence similarity 20, member C [Source:HGNC Symbol;Acc:HGNC:22140]"	9.23	8.66	19.32	53.04	45.53	69.28	0.24	-2.09	0.03	0.3	down	yes
MSTRG.24338	ZFAND2A	ENST00000401903;ENST00000397083;ENST00000316495;MSTRG.24338.2;ENST00000471448;ENST00000574135;ENST00000484977	GO:0000502(proteasome complex);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0071243(cellular response to arsenic-containing substance)	NA	NA	NA	"zinc finger, AN1-type domain 2A [Source:HGNC Symbol;Acc:HGNC:28073]"	13.21	13.41	10.96	2.96	3.83	1.88	3.33	1.73	0.01	0.24	up	yes
MSTRG.24343	MAFK	ENST00000343242;MSTRG.24343.2;ENST00000403150;ENST00000406174	"GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001221(transcription cofactor binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007399(nervous system development);GO:0007596(blood coagulation);GO:0043565(sequence-specific DNA binding);GO:0071535(RING-like zinc finger domain binding)"	NA	NA	NA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K [Source:HGNC Symbol;Acc:HGNC:6782]	16.61	11.1	15.73	2.82	4.03	3.93	4.08	2.03	0	0.12	up	yes
MSTRG.24358	FTSJ2	MSTRG.24358.1;MSTRG.24358.2;MSTRG.24358.3;ENST00000467199;MSTRG.24358.7;MSTRG.24358.5;MSTRG.24358.6;ENST00000242257;ENST00000440306;ENST00000486040;ENST00000407040	GO:0001510(RNA methylation);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0006364(rRNA processing);GO:0008168(methyltransferase activity);GO:0008283(cell proliferation);GO:0008650(rRNA (uridine-2'-O-)-methyltransferase activity);GO:0031167(rRNA methylation);GO:0032259(methylation)	NA	NA	NA	FtsJ RNA methyltransferase homolog 2 (E. coli) [Source:HGNC Symbol;Acc:HGNC:16352]	2.85	2.98	4.86	19.47	14.72	13.06	0.24	-2.07	0.01	0.2	down	yes
MSTRG.24359	NUDT1	ENST00000356714;MSTRG.24359.2;MSTRG.24359.3;ENST00000397046;ENST00000397048;ENST00000454650;ENST00000339737;ENST00000343985;ENST00000397049;ENST00000471348;ENST00000487426	"GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006195(purine nucleotide catabolic process);GO:0006203(dGTP catabolic process);GO:0006281(DNA repair);GO:0006979(response to oxidative stress);GO:0008413(8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity);GO:0016787(hydrolase activity);GO:0030515(snoRNA binding);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0035539(8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity);GO:0036219(GTP diphosphatase activity);GO:0042262(DNA protection);GO:0044281(small molecule metabolic process);GO:0046061(dATP catabolic process);GO:0046872(metal ion binding);GO:0047693(ATP diphosphatase activity);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0070062(extracellular exosome)"	NA	NA	NA	nudix (nucleoside diphosphate linked moiety X)-type motif 1 [Source:HGNC Symbol;Acc:HGNC:8048]	4.56	4.53	3.94	11.38	12.09	11.3	0.43	-1.23	0	0.13	down	yes
MSTRG.24363	IQCE	ENST00000623361;MSTRG.24363.2;ENST00000402050;MSTRG.24363.4;ENST00000415271;ENST00000470731;ENST00000438376;ENST00000325997;ENST00000476665;ENST00000404984;ENST00000611775;ENST00000325979;ENST00000422276;ENST00000497572;ENST00000427817;ENST00000490913;ENST00000423196;ENST00000486730	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0072372(primary cilium)	NA	NA	NA	IQ motif containing E [Source:HGNC Symbol;Acc:HGNC:29171]	1.02	1.09	1.42	3.77	2.46	3.81	0.49	-1.03	0.03	0.28	down	yes
MSTRG.2438	NUAK2	MSTRG.2438.1;ENST00000367157	"GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030036(actin cytoskeleton organization);GO:0031588(AMP-activated protein kinase complex);GO:0032007(negative regulation of TOR signaling);GO:0035556(intracellular signal transduction);GO:0042149(cellular response to glucose starvation);GO:0043066(negative regulation of apoptotic process)"	NA	NA	NA	"NUAK family, SNF1-like kinase, 2 [Source:HGNC Symbol;Acc:HGNC:29558]"	7.8	6.2	8.37	0.73	2.69	0.57	4.22	2.08	0.04	0.31	up	yes
MSTRG.24396	ACTB	ENST00000464611;ENST00000331789;ENST00000425660;ENST00000462494;ENST00000493945;ENST00000484841;ENST00000473257;ENST00000477812;ENST00000432588;ENST00000480301;ENST00000443528;MSTRG.24396.12;ENST00000417101;ENST00000414620;MSTRG.24396.16	NA	NA	NA	NA	NA	247	232.48	251.1	774.85	740.28	399.54	0.35	-1.53	0.03	0.3	down	yes
MSTRG.24440	C1GALT1	ENST00000429911;ENST00000419721;MSTRG.24440.3;ENST00000436587;ENST00000467716;ENST00000476068;ENST00000223122;ENST00000402468	"GO:0000139(Golgi membrane);GO:0001525(angiogenesis);GO:0001822(kidney development);GO:0005515(protein binding);GO:0006493(protein O-linked glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016263(glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity);GO:0016266(O-glycan processing);GO:0016757(transferase activity, transferring glycosyl groups);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding);GO:0060576(intestinal epithelial cell development)"	00512(Mucin type O-Glycan biosynthesis);01100(Metabolic pathways)	K00731	2.4.1.122	"core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24337]"	12.45	15.29	9.82	4.96	3.41	1.74	2.49	1.32	0.05	0.33	up	yes
MSTRG.24446	RPA3	ENST00000223129;ENST00000406109;ENST00000396682;ENST00000401447;ENST00000483031;ENST00000462723;ENST00000463632	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000718(nucleotide-excision repair, DNA damage removal);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0000724(double-strand break repair via homologous recombination);GO:0000730(DNA recombinase assembly);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005662(DNA replication factor A complex);GO:0006260(DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006298(mismatch repair);GO:0006302(double-strand break repair);GO:0006310(DNA recombination);GO:0007346(regulation of mitotic cell cycle);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0034605(cellular response to heat);GO:0042127(regulation of cell proliferation);GO:0042276(error-prone translesion synthesis);GO:0042769(DNA damage response, detection of DNA damage);GO:0070987(error-free translesion synthesis);GO:1900034(regulation of cellular response to heat)"	NA	NA	NA	"replication protein A3, 14kDa [Source:HGNC Symbol;Acc:HGNC:10291]"	5.78	6.61	5.44	16.93	19.18	15.41	0.36	-1.46	0	0.16	down	yes
MSTRG.24458	ICA1	ENST00000402384;ENST00000406470;MSTRG.24458.3;ENST00000265577;MSTRG.24458.5;MSTRG.24458.6;ENST00000396675;ENST00000455539;ENST00000339809;ENST00000401396;ENST00000422063;ENST00000486677;MSTRG.24458.12;ENST00000470696;ENST00000407906;ENST00000490041;ENST00000447326;ENST00000476942;ENST00000430867;ENST00000446305	GO:0000139(Golgi membrane);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006836(neurotransmitter transport);GO:0019904(protein domain specific binding);GO:0030054(cell junction);GO:0030658(transport vesicle membrane);GO:0030667(secretory granule membrane);GO:0030672(synaptic vesicle membrane);GO:0050796(regulation of insulin secretion)	04940(Type I diabetes mellitus)	NA	NA	"islet cell autoantigen 1, 69kDa [Source:HGNC Symbol;Acc:HGNC:5343]"	11.15	10.64	9.66	3.05	3.09	4.73	2.79	1.48	0.01	0.19	up	yes
MSTRG.24476	HDAC9	ENST00000417496;ENST00000433709;ENST00000411993;ENST00000461159;ENST00000474742;ENST00000413380;ENST00000430454;ENST00000476135;ENST00000622668;ENST00000405010;ENST00000406451;ENST00000428307;ENST00000461409;ENST00000406072;ENST00000446646;ENST00000401921;ENST00000523867;ENST00000441542;ENST00000441986;ENST00000471887;MSTRG.24476.25;ENST00000456174;MSTRG.24476.27;MSTRG.24476.28;ENST00000524023;ENST00000490851;ENST00000483142	"GO:0000118(histone deacetylase complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001975(response to amphetamine);GO:0003714(transcription corepressor activity);GO:0004407(histone deacetylase activity);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006954(inflammatory response);GO:0007219(Notch signaling pathway);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0016568(chromatin modification);GO:0016575(histone deacetylation);GO:0030182(neuron differentiation);GO:0030183(B cell differentiation);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0032869(cellular response to insulin stimulus);GO:0033558(protein deacetylase activity);GO:0034983(peptidyl-lysine deacetylation);GO:0035097(histone methyltransferase complex);GO:0042113(B cell activation);GO:0042826(histone deacetylase binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0048742(regulation of skeletal muscle fiber development);GO:0051153(regulation of striated muscle cell differentiation);GO:0070491(repressing transcription factor binding);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis)"	NA	NA	NA	histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065]	5.82	9.37	10.53	1.04	1.24	0.67	3.95	1.98	0	0.19	up	yes
MSTRG.24515	GPNMB	ENST00000258733;ENST00000381990;ENST00000409458;ENST00000459927;ENST00000487890;ENST00000474157;ENST00000479625;ENST00000470994;ENST00000463011;ENST00000478451;ENST00000468723	GO:0001649(osteoblast differentiation);GO:0005178(integrin binding);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0008201(heparin binding);GO:0008285(negative regulation of cell proliferation);GO:0016021(integral component of membrane);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0030282(bone mineralization);GO:0032720(negative regulation of tumor necrosis factor production);GO:0042470(melanosome)	NA	NA	NA	glycoprotein (transmembrane) nmb [Source:HGNC Symbol;Acc:HGNC:4462]	10.62	6.71	8.18	4.08	2.63	2.98	2.41	1.27	0.03	0.28	up	yes
MSTRG.2452	RAB29	MSTRG.2452.1;MSTRG.2452.2;MSTRG.2452.4;MSTRG.2452.6;ENST00000367139;MSTRG.2452.7;MSTRG.2452.3;MSTRG.2452.5;ENST00000235932;ENST00000528078;ENST00000437324;ENST00000446390;ENST00000414729;ENST00000492534;ENST00000533111	"GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005773(vacuole);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006895(Golgi to endosome transport);GO:0006913(nucleocytoplasmic transport);GO:0007030(Golgi organization);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0030154(cell differentiation);GO:0031982(vesicle);GO:0032438(melanosome organization);GO:0032482(Rab protein signal transduction);GO:0035526(retrograde transport, plasma membrane to Golgi);GO:0042470(melanosome);GO:0048471(perinuclear region of cytoplasm);GO:0051223(regulation of protein transport);GO:0070062(extracellular exosome);GO:0090316(positive regulation of intracellular protein transport)"	NA	NA	NA	"RAB29, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9789]"	8.64	8.75	13.45	4.4	4.34	4.34	2.02	1.02	0.03	0.3	up	yes
MSTRG.24528	DFNA5	ENST00000342947;ENST00000419307;ENST00000479636;ENST00000409970;ENST00000409775;ENST00000430096;ENST00000415480;ENST00000446822;ENST00000469133;ENST00000411476;ENST00000559637;ENST00000493723;ENST00000414428;ENST00000473990	GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0007605(sensory perception of sound);GO:0008285(negative regulation of cell proliferation);GO:0060113(inner ear receptor cell differentiation);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)	NA	NA	NA	"deafness, autosomal dominant 5 [Source:HGNC Symbol;Acc:HGNC:2810]"	6.68	7.32	11.13	2.06	2.28	2.18	2.81	1.49	0.01	0.24	up	yes
MSTRG.24538	HNRNPA2B1	MSTRG.24538.1;MSTRG.24538.2;MSTRG.24538.3;MSTRG.24538.4;ENST00000476233;ENST00000354667;ENST00000618183;ENST00000360787;ENST00000463181;ENST00000356674;ENST00000490912;ENST00000495810	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0016020(membrane);GO:0030529(ribonucleoprotein complex);GO:0043047(single-stranded telomeric DNA binding);GO:0044822(poly(A) RNA binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0050658(RNA transport);GO:0071013(catalytic step 2 spliceosome);GO:0097157(pre-mRNA intronic binding)"	NA	NA	NA	heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033]	33.28	33.84	28.96	138.13	123.96	58.55	0.27	-1.91	0.03	0.29	down	yes
MSTRG.24548	HOTAIRM1	ENST00000495032;ENST00000434063;ENST00000429611;ENST00000425358;ENST00000428939;ENST00000616712;ENST00000593300	NA	NA	NA	NA	NA	3.96	4.11	2.88	1.36	0.8	1.36	2.11	1.08	0.03	0.28	up	yes
MSTRG.2456	RAB7B	ENST00000617070;ENST00000623597;ENST00000617991;ENST00000623893;MSTRG.2456.5	NA	NA	NA	NA	NA	0.18	0.23	0.23	10.34	8.21	9.37	0.11	-3.15	0	0.08	down	yes
MSTRG.24600	GARS	ENST00000389266;ENST00000627489;ENST00000454308;ENST00000478124;ENST00000484093;ENST00000470392;ENST00000444666;ENST00000465748;ENST00000485784;ENST00000496643	GO:0000166(nucleotide binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004820(glycine-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006418(tRNA aminoacylation for protein translation);GO:0006426(glycyl-tRNA aminoacylation);GO:0010467(gene expression);GO:0015966(diadenosine tetraphosphate biosynthetic process);GO:0030141(secretory granule);GO:0030424(axon);GO:0046983(protein dimerization activity);GO:0070062(extracellular exosome)	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	glycyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:4162]	240.7	242.79	201.17	56.97	49.07	25.49	4.46	2.16	0.02	0.25	up	yes
MSTRG.2470	DYRK3	ENST00000367109;ENST00000367108;ENST00000489878;ENST00000441486;ENST00000367106	"GO:0000287(magnesium ion binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0006468(protein phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030218(erythrocyte differentiation)"	NA	NA	NA	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 [Source:HGNC Symbol;Acc:HGNC:3094]	2.1	2.03	1.94	0.21	0.51	0.84	2.27	1.18	0.01	0.22	up	yes
MSTRG.24712	AC017116.11	MSTRG.24712.1;MSTRG.24712.2;MSTRG.24712.3;ENST00000448521;ENST00000490734;ENST00000456905;ENST00000458579;ENST00000439983;ENST00000440166;ENST00000441840;MSTRG.24712.11;ENST00000464762;ENST00000439815;ENST00000498733;ENST00000452943;ENST00000429716;ENST00000468694;ENST00000494774;ENST00000411855;ENST00000423561;ENST00000497184;ENST00000432854;ENST00000449997;ENST00000452661;ENST00000445938;ENST00000425727	NA	NA	NA	NA	NA	2.4	2.66	4.31	8.87	8.91	9.36	0.39	-1.36	0.02	0.26	down	yes
MSTRG.24719	DDX56	ENST00000258772;ENST00000446987;ENST00000421223;ENST00000479602;ENST00000485367;ENST00000433257;ENST00000467318;ENST00000431640;ENST00000448192;ENST00000415758;ENST00000473924;ENST00000479440	GO:0003676(nucleic acid binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0010501(RNA secondary structure unwinding);GO:0016020(membrane);GO:0044822(poly(A) RNA binding)	NA	NA	NA	DEAD (Asp-Glu-Ala-Asp) box helicase 56 [Source:HGNC Symbol;Acc:HGNC:18193]	14.43	16.63	21.17	36.34	45.15	31.54	0.44	-1.18	0.03	0.28	down	yes
MSTRG.24724	ZMIZ2	MSTRG.24724.1;MSTRG.24724.2;MSTRG.24724.3;MSTRG.24724.4;ENST00000413916;ENST00000457123;MSTRG.24724.7;MSTRG.24724.8;ENST00000309315;ENST00000416856;ENST00000441627;ENST00000492001;ENST00000433667;ENST00000265346;ENST00000615423;MSTRG.24724.16;ENST00000478045;MSTRG.24724.17;ENST00000463056;ENST00000480964;ENST00000492558;ENST00000463931;ENST00000482322	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0006351(transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0043596(nuclear replication fork);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	"zinc finger, MIZ-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22229]"	14.16	12.09	9.92	3.93	3.91	4.11	2.78	1.48	0	0.17	up	yes
MSTRG.24726	PPIA	ENST00000481437;ENST00000451562;ENST00000468812;ENST00000489459;ENST00000355968;ENST00000620047;ENST00000479021;ENST00000415933;ENST00000494484;ENST00000480603	GO:0000413(protein peptidyl-prolyl isomerization);GO:0002576(platelet degranulation);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0006278(RNA-dependent DNA replication);GO:0006457(protein folding);GO:0007596(blood coagulation);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019061(uncoating of virus);GO:0019068(virion assembly);GO:0019076(viral release from host cell);GO:0030168(platelet activation);GO:0030260(entry into host cell);GO:0034389(lipid particle organization);GO:0042277(peptide binding);GO:0044822(poly(A) RNA binding);GO:0045069(regulation of viral genome replication);GO:0045070(positive regulation of viral genome replication);GO:0046790(virion binding);GO:0050714(positive regulation of protein secretion);GO:0050900(leukocyte migration);GO:0051082(unfolded protein binding);GO:0070062(extracellular exosome);GO:0075713(establishment of integrated proviral latency)	NA	NA	NA	peptidylprolyl isomerase A (cyclophilin A) [Source:HGNC Symbol;Acc:HGNC:9253]	270.44	287.02	217.89	540.78	604.92	400.75	0.47	-1.09	0.03	0.3	down	yes
MSTRG.24727	H2AFV	ENST00000222690;ENST00000437072;ENST00000349299;ENST00000308153;ENST00000350771;ENST00000381124;ENST00000521529;ENST00000446531	GO:0000786(nucleosome);GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0008150(biological_process);GO:0046982(protein heterodimerization activity);GO:0070062(extracellular exosome)	05322(Systemic lupus erythematosus)	NA	NA	"H2A histone family, member V [Source:HGNC Symbol;Acc:HGNC:20664]"	12.68	11.41	7.98	44.83	35.06	22.13	0.3	-1.73	0.03	0.3	down	yes
MSTRG.24728	H2AFV	MSTRG.24728.1	NA	NA	NA	NA	NA	3.04	2.93	2.03	18.7	20.39	9.85	0.2	-2.36	0.01	0.24	down	yes
MSTRG.24731	SNHG15	ENST00000577700;ENST00000578968;MSTRG.24731.3;MSTRG.24731.4;MSTRG.24731.5;MSTRG.24731.6;ENST00000579383;ENST00000585030;ENST00000580458;ENST00000584327;ENST00000582727;ENST00000580528	NA	NA	NA	NA	NA	10.97	7.6	7.79	3.58	5.9	4.72	2.07	1.05	0.01	0.24	up	yes
MSTRG.24740	SEPT7P2	ENST00000444755;ENST00000429741;ENST00000338231;MSTRG.24740.3;MSTRG.24740.6;MSTRG.24740.5;MSTRG.24740.7;MSTRG.24740.8;MSTRG.24740.9;MSTRG.24740.10;ENST00000428414;ENST00000413357;ENST00000413875;ENST00000398921;ENST00000428867;ENST00000450436	NA	NA	NA	NA	NA	11.48	11.69	11.63	2.01	1.93	1.29	4.31	2.11	0	0.13	up	yes
MSTRG.24744	IGFBP3	ENST00000381086;ENST00000613132;ENST00000275521;ENST00000460209;ENST00000381083;ENST00000428530;ENST00000417621;ENST00000448817;ENST00000465642;ENST00000460477	GO:0001558(regulation of cell growth);GO:0001649(osteoblast differentiation);GO:0001933(negative regulation of protein phosphorylation);GO:0001968(fibronectin binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0008160(protein tyrosine phosphatase activator activity);GO:0008285(negative regulation of cell proliferation);GO:0009968(negative regulation of signal transduction);GO:0010906(regulation of glucose metabolic process);GO:0014912(negative regulation of smooth muscle cell migration);GO:0016942(insulin-like growth factor binding protein complex);GO:0031994(insulin-like growth factor I binding);GO:0031995(insulin-like growth factor II binding);GO:0040008(regulation of growth);GO:0042567(insulin-like growth factor ternary complex);GO:0043065(positive regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0043410(positive regulation of MAPK cascade);GO:0043567(regulation of insulin-like growth factor receptor signaling pathway);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0044267(cellular protein metabolic process);GO:0044342(type B pancreatic cell proliferation);GO:0045663(positive regulation of myoblast differentiation);GO:0046872(metal ion binding);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0070062(extracellular exosome)	04115(p53 signaling pathway)	NA	NA	insulin-like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]	17.86	17.51	42.95	0.66	0.32	2.17	14.58	3.87	0.02	0.25	up	yes
MSTRG.24752	UPP1	MSTRG.24752.2;MSTRG.24752.3;MSTRG.24752.1;MSTRG.24752.4;ENST00000416681;MSTRG.24752.6;MSTRG.24752.7;MSTRG.24752.11;MSTRG.24752.8;MSTRG.24752.10;MSTRG.24752.9;ENST00000331803;MSTRG.24752.13;MSTRG.24752.14;ENST00000432131;MSTRG.24752.15;ENST00000457596;MSTRG.24752.18;ENST00000421046;ENST00000395564;ENST00000436673;ENST00000395560;ENST00000444999;ENST00000482015;ENST00000417464;ENST00000495446	"GO:0003824(catalytic activity);GO:0004850(uridine phosphorylase activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006218(uridine catabolic process);GO:0006220(pyrimidine nucleotide metabolic process);GO:0009116(nucleoside metabolic process);GO:0009166(nucleotide catabolic process);GO:0016763(transferase activity, transferring pentosyl groups);GO:0042149(cellular response to glucose starvation);GO:0043097(pyrimidine nucleoside salvage);GO:0044206(UMP salvage);GO:0044281(small molecule metabolic process);GO:0046108(uridine metabolic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0055086(nucleobase-containing small molecule metabolic process)"	00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);01100(Metabolic pathways)	NA	NA	uridine phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12576]	54.04	55.96	60.02	16.54	15.43	13.8	3.35	1.75	0	0.1	up	yes
MSTRG.2479	CD55	ENST00000367064;ENST00000367063;ENST00000391921;ENST00000488171;ENST00000314754;ENST00000367067;ENST00000343420;ENST00000465534;ENST00000476590	"GO:0001618(virus receptor activity);GO:0004857(enzyme inhibitor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006958(complement activation, classical pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007283(spermatogenesis);GO:0008289(lipid binding);GO:0009986(cell surface);GO:0016324(apical plasma membrane);GO:0030449(regulation of complement activation);GO:0031225(anchored component of membrane);GO:0031664(regulation of lipopolysaccharide-mediated signaling pathway);GO:0035743(CD4-positive, alpha-beta T cell cytokine production);GO:0043086(negative regulation of catalytic activity);GO:0043434(response to peptide hormone);GO:0045087(innate immune response);GO:0045121(membrane raft);GO:0045730(respiratory burst);GO:0045916(negative regulation of complement activation);GO:0046718(viral entry into host cell);GO:0060137(maternal process involved in parturition);GO:0070062(extracellular exosome);GO:2000516(positive regulation of CD4-positive, alpha-beta T cell activation);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation)"	04610(Complement and coagulation cascades);04640(Hematopoietic cell lineage);05416(Viral myocarditis)	NA	NA	"CD55 molecule, decay accelerating factor for complement (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665]"	76.53	96.7	79.84	12.87	11.94	21.08	5.52	2.46	0.01	0.2	up	yes
MSTRG.24806	CCT6P3	ENST00000419314;ENST00000426828;ENST00000452026	NA	NA	NA	NA	NA	2.66	2.24	1.75	0.64	0.68	0.6	2.04	1.03	0.01	0.21	up	yes
MSTRG.24815	SNORA22	MSTRG.24815.1;MSTRG.24815.2;ENST00000434500;ENST00000443108;ENST00000442266;ENST00000383907	NA	NA	NA	NA	NA	5.56	6.38	4.89	1.89	1.23	0.97	2.46	1.3	0.01	0.2	up	yes
MSTRG.24823	RP5-1132H15.1	MSTRG.24823.1	NA	NA	NA	NA	NA	0	0.19	0.1	1.17	1.14	0.9	0.48	-1.05	0	0.1	down	yes
MSTRG.24842	.	MSTRG.24842.3;MSTRG.24842.1;MSTRG.24842.2;MSTRG.24842.4;MSTRG.24842.5;ENST00000428370;MSTRG.24842.8;MSTRG.24842.9	NA	NA	NA	NA	NA	16.15	12.85	9.56	3.44	3.76	3.41	3.28	1.71	0.01	0.21	up	yes
MSTRG.24861	STAG3L4	ENST00000416602;MSTRG.24861.1;ENST00000472361;ENST00000352103	NA	NA	NA	NA	NA	11.47	12.07	9.18	4.05	3.38	6.33	2.33	1.22	0.04	0.31	up	yes
MSTRG.24870	.	MSTRG.24870.1	NA	NA	NA	NA	NA	0.82	1.32	1.74	2.86	4.15	3.14	0.49	-1.03	0.04	0.32	down	yes
MSTRG.24874	NSUN5P2	MSTRG.24874.1;MSTRG.24874.3;MSTRG.24874.2;MSTRG.24874.4;ENST00000602348;MSTRG.24874.6;ENST00000444583;ENST00000485741;ENST00000388955;ENST00000457352	NA	NA	NA	NA	NA	4.32	3.38	2.87	1.31	1.13	1.23	2.15	1.1	0.01	0.21	up	yes
MSTRG.24876	STAG3L3	ENST00000436857;MSTRG.24876.2;ENST00000428423;ENST00000608210;ENST00000448173;ENST00000423834;ENST00000569650	NA	NA	NA	NA	NA	2.25	2.49	4.17	8.63	9.21	11.84	0.37	-1.43	0.03	0.28	down	yes
MSTRG.24879	STAG3L3	MSTRG.24879.1;MSTRG.24879.2	NA	NA	NA	NA	NA	0	0.77	0.03	1.03	1.12	1	0.49	-1.02	0.04	0.32	down	yes
MSTRG.24880	STAG3L3	MSTRG.24880.2;MSTRG.24880.1;MSTRG.24880.3	NA	NA	NA	NA	NA	0.29	0.23	0.94	4.03	3.1	1.81	0.33	-1.62	0.03	0.29	down	yes
MSTRG.2489	SERTAD4	ENST00000367012;MSTRG.2489.2;MSTRG.2489.3;MSTRG.2489.4;ENST00000490620;ENST00000482421	GO:0005634(nucleus)	NA	NA	NA	SERTA domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25236]	1.28	1.75	4.18	12.88	13.05	5.54	0.23	-2.15	0.04	0.33	down	yes
MSTRG.249	TARDBP	MSTRG.249.1	NA	NA	NA	NA	NA	5.06	2.85	2.15	0.43	1.1	0.71	3.06	1.61	0.02	0.25	up	yes
MSTRG.24912	VPS37D	MSTRG.24912.1;ENST00000324941	GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016032(viral process);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0019068(virion assembly);GO:0019082(viral protein processing);GO:0031902(late endosome membrane);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0075733(intracellular transport of virus)	04144(Endocytosis)	NA	NA	vacuolar protein sorting 37 homolog D (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:18287]	6.24	4.84	4.15	0.52	0.38	0.55	4.41	2.14	0	0.14	up	yes
MSTRG.24925	RFC2	MSTRG.24925.1;ENST00000352131;ENST00000621097;ENST00000055077;ENST00000485545;ENST00000497430;ENST00000470266;ENST00000494019;ENST00000480432;ENST00000479105;ENST00000491206;ENST00000493156;ENST00000463194;ENST00000473493	"GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003689(DNA clamp loader activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005663(DNA replication factor C complex);GO:0005794(Golgi apparatus);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0015979(photosynthesis);GO:0015995(chlorophyll biosynthetic process);GO:0016851(magnesium chelatase activity);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0042276(error-prone translesion synthesis);GO:0042769(DNA damage response, detection of DNA damage);GO:0070987(error-free translesion synthesis)"	03030(DNA replication);03420(Nucleotide excision repair);03430(Mismatch repair)	NA	NA	"replication factor C (activator 1) 2, 40kDa [Source:HGNC Symbol;Acc:HGNC:9970]"	12.79	17.29	12.58	36.29	34.61	28.33	0.38	-1.38	0	0.17	down	yes
MSTRG.24926	CLIP2	ENST00000361545;ENST00000223398;MSTRG.24926.3;ENST00000395060;ENST00000487091;ENST00000493166;ENST00000482424;ENST00000491075;ENST00000474962;ENST00000487447	GO:0005515(protein binding);GO:0005875(microtubule associated complex);GO:0005881(cytoplasmic microtubule);GO:0035371(microtubule plus-end);GO:0051010(microtubule plus-end binding)	NA	NA	NA	CAP-GLY domain containing linker protein 2 [Source:HGNC Symbol;Acc:HGNC:2586]	14.51	14.26	13.62	3.57	4.09	7.15	3.05	1.61	0.01	0.24	up	yes
MSTRG.24927	GTF2IRD1	ENST00000265755;MSTRG.24927.2;MSTRG.24927.3;ENST00000455841;MSTRG.24927.5;ENST00000424337;MSTRG.24927.7;ENST00000476977;ENST00000489094;ENST00000486086	"GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003705(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organismal development);GO:0014886(transition between slow and fast fiber)"	03022(Basal transcription factors)	NA	NA	GTF2I repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:4661]	11.94	10.89	11.31	3.3	3.29	4.5	2.89	1.53	0	0.14	up	yes
MSTRG.2494	RCOR3	MSTRG.2494.1;ENST00000367006;MSTRG.2494.4;MSTRG.2494.5;MSTRG.2494.6;MSTRG.2494.8;MSTRG.2494.9;ENST00000452621;ENST00000528926;ENST00000419091;ENST00000528408;ENST00000472734;ENST00000529572;ENST00000367005;ENST00000534460;ENST00000529763;ENST00000485186;ENST00000486666;ENST00000528066;ENST00000526255	"GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0019899(enzyme binding)"	NA	NA	NA	REST corepressor 3 [Source:HGNC Symbol;Acc:HGNC:25594]	7.41	6.39	5.69	2.29	2.58	1.47	2.4	1.26	0.02	0.26	up	yes
MSTRG.24941	WBSCR16	ENST00000614461;MSTRG.24941.2;MSTRG.24941.3;ENST00000610322;ENST00000618102;ENST00000616051;ENST00000618035;ENST00000615250	GO:0005575(cellular_component);GO:0005739(mitochondrion);GO:0008150(biological_process);GO:0044822(poly(A) RNA binding)	NA	NA	NA	Williams-Beuren syndrome chromosome region 16 [Source:HGNC Symbol;Acc:HGNC:14948]	11.32	10.7	10.22	23.06	26.9	16.69	0.49	-1.02	0.03	0.3	down	yes
MSTRG.2508	DTL	ENST00000542077;ENST00000366991;ENST00000475419;ENST00000489149;ENST00000463791	"GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0009411(response to UV);GO:0019985(translesion synthesis);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031465(Cul4B-RING E3 ubiquitin ligase complex);GO:0031572(G2 DNA damage checkpoint);GO:0031965(nuclear membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0043231(intracellular membrane-bounded organelle);GO:0051726(regulation of cell cycle)"	NA	NA	NA	denticleless E3 ubiquitin protein ligase homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:30288]	2.56	4.1	1.33	17.54	14.43	6.25	0.2	-2.35	0.03	0.29	down	yes
MSTRG.25105	SLC25A13	ENST00000265631;ENST00000416240;MSTRG.25105.3;ENST00000494085;ENST00000490072;ENST00000484495;ENST00000492869;ENST00000472162;ENST00000487710	GO:0005215(transporter activity);GO:0005313(L-glutamate transmembrane transporter activity);GO:0005509(calcium ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005887(integral component of plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006094(gluconeogenesis);GO:0006754(ATP biosynthetic process);GO:0006810(transport);GO:0015183(L-aspartate transmembrane transporter activity);GO:0015810(aspartate transport);GO:0015813(L-glutamate transport);GO:0043490(malate-aspartate shuttle);GO:0044281(small molecule metabolic process);GO:0045333(cellular respiration);GO:0051592(response to calcium ion);GO:0089711(L-glutamate transmembrane transport);GO:0089712(L-aspartate transmembrane transport)	NA	NA	NA	"solute carrier family 25 (aspartate/glutamate carrier), member 13 [Source:HGNC Symbol;Acc:HGNC:10983]"	6.08	5.16	6.96	19.97	20.49	16.16	0.35	-1.5	0.01	0.2	down	yes
MSTRG.25117	ASNS	ENST00000175506;ENST00000394309;ENST00000454046;ENST00000394308;ENST00000422745;ENST00000455086;ENST00000444334;ENST00000487714;ENST00000462436;ENST00000442734;ENST00000495255;ENST00000437657;ENST00000448127;ENST00000453600;ENST00000451771;ENST00000414884	GO:0001889(liver development);GO:0004066(asparagine synthase (glutamine-hydrolyzing) activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006520(cellular amino acid metabolic process);GO:0006529(asparagine biosynthetic process);GO:0006541(glutamine metabolic process);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0009416(response to light stimulus);GO:0009612(response to mechanical stimulus);GO:0009636(response to toxic substance);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031427(response to methotrexate);GO:0031667(response to nutrient levels);GO:0032354(response to follicle-stimulating hormone);GO:0032870(cellular response to hormone stimulus);GO:0034641(cellular nitrogen compound metabolic process);GO:0036499(PERK-mediated unfolded protein response);GO:0042149(cellular response to glucose starvation);GO:0042803(protein homodimerization activity);GO:0043066(negative regulation of apoptotic process);GO:0043200(response to amino acid);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0045931(positive regulation of mitotic cell cycle);GO:0048037(cofactor binding);GO:0070981(L-asparagine biosynthetic process)	"00250(Alanine, aspartate and glutamate metabolism);00910(Nitrogen metabolism);01100(Metabolic pathways)"	NA	NA	asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:HGNC:753]	86.97	100.49	119.5	19.25	19.46	13.04	4.94	2.3	0	0.17	up	yes
MSTRG.25130	SMURF1	MSTRG.25130.1;MSTRG.25130.4;MSTRG.25130.5;MSTRG.25130.2;MSTRG.25130.3;ENST00000361368;ENST00000361125;MSTRG.25130.9;MSTRG.25130.10;MSTRG.25130.8;ENST00000480055;ENST00000472627	GO:0000209(protein polyubiquitination);GO:0002230(positive regulation of defense response to virus by host);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006611(protein export from nucleus);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007398(ectoderm development);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0030154(cell differentiation);GO:0030279(negative regulation of ossification);GO:0030509(BMP signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0030579(ubiquitin-dependent SMAD protein catabolic process);GO:0032801(receptor catabolic process);GO:0034394(protein localization to cell surface);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0048185(activin binding);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0070411(I-SMAD binding);GO:0070412(R-SMAD binding);GO:0071211(protein targeting to vacuole involved in autophagy);GO:0072661(protein targeting to plasma membrane);GO:0098779(activation of mitophagy in response to mitochondrial depolarization);GO:1903861(positive regulation of dendrite extension);GO:2000060(positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process)	04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04350(TGF-beta signaling pathway)	NA	NA	SMAD specific E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:16807]	15.75	14.33	13.73	5.33	6.2	7.66	2.38	1.25	0	0.17	up	yes
MSTRG.25159	MCM7	ENST00000489841;ENST00000354230;ENST00000621318;MSTRG.25159.4;ENST00000343023;ENST00000485286;ENST00000303887;ENST00000491245;ENST00000493352;MSTRG.25159.10;ENST00000463722;ENST00000425308;ENST00000467516;ENST00000465688;ENST00000465738	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000785(chromatin);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006974(cellular response to DNA damage stimulus);GO:0008283(cell proliferation);GO:0016020(membrane);GO:0032508(DNA duplex unwinding);GO:0042325(regulation of phosphorylation);GO:0042493(response to drug);GO:0042555(MCM complex);GO:0071310(cellular response to organic substance);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071466(cellular response to xenobiotic stimulus)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950]	28.26	32.77	34.21	74.51	79.09	71.55	0.4	-1.3	0	0.13	down	yes
MSTRG.25160	MIR25	ENST00000384816	NA	NA	NA	NA	NA	0	0.69	0.8	2.4	4.75	2.98	0.3	-1.75	0.03	0.3	down	yes
MSTRG.25166	CNPY4	ENST00000262932;MSTRG.25166.2;ENST00000470153;ENST00000483756;ENST00000480692;ENST00000462193	GO:0005102(receptor binding);GO:0005576(extracellular region)	NA	NA	NA	canopy FGF signaling regulator 4 [Source:HGNC Symbol;Acc:HGNC:28631]	2.27	2.11	3.48	14.91	17.92	20.75	0.21	-2.26	0	0.18	down	yes
MSTRG.25204	RP11-395B7.4	MSTRG.25204.1;ENST00000441882;ENST00000448513	NA	NA	NA	NA	NA	0.26	0.17	0.18	1.02	2.75	1.92	0.49	-1.02	0.05	0.34	down	yes
MSTRG.25206	SRRT	MSTRG.25206.1;MSTRG.25206.3;MSTRG.25206.2;MSTRG.25206.4;MSTRG.25206.5;ENST00000620394;ENST00000614484;ENST00000618262;ENST00000614370;ENST00000618411;ENST00000611405;ENST00000431645;ENST00000423692;ENST00000474896;ENST00000460194;ENST00000448764;ENST00000449389;ENST00000466432;ENST00000487311;ENST00000469602;ENST00000478693;ENST00000445337;ENST00000477529	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008283(cell proliferation);GO:0031053(primary miRNA processing);GO:0044822(poly(A) RNA binding);GO:0046685(response to arsenic-containing substance);GO:0050769(positive regulation of neurogenesis);GO:0097150(neuronal stem cell maintenance)"	NA	NA	NA	"serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]"	8.82	7.54	8.73	26.33	28.75	16.96	0.36	-1.46	0.02	0.27	down	yes
MSTRG.25216	SH2B2	ENST00000617975;MSTRG.25216.3;MSTRG.25216.5	NA	NA	NA	NA	NA	3.24	2.03	2.08	0.5	0.44	1.41	2.53	1.34	0.02	0.25	up	yes
MSTRG.2522	ATF3	ENST00000366981;ENST00000366987;ENST00000613954;ENST00000465155;ENST00000341491;ENST00000366985;ENST00000492118;ENST00000336937;ENST00000366983;ENST00000464547;ENST00000613104	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001228(RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006094(gluconeogenesis);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0034198(cellular response to amino acid starvation);GO:0035914(skeletal muscle cell differentiation);GO:0036499(PERK-mediated unfolded protein response);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0061394(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:1903984(positive regulation of TRAIL-activated apoptotic signaling pathway);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:1990622(CHOP-ATF3 complex)"	NA	NA	NA	activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785]	26.51	63.99	54.06	4.64	6.02	2.67	5.93	2.57	0.01	0.21	up	yes
MSTRG.25237	LRWD1	ENST00000292616;ENST00000463739;ENST00000464107;ENST00000473880;ENST00000476270;ENST00000485808;ENST00000485417;ENST00000468175	GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005664(nuclear origin of replication recognition complex);GO:0005721(pericentric heterochromatin);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0006270(DNA replication initiation);GO:0006325(chromatin organization);GO:0008327(methyl-CpG binding);GO:0016568(chromatin modification);GO:0031933(telomeric heterochromatin);GO:0035064(methylated histone binding);GO:0071169(establishment of protein localization to chromatin)	NA	NA	NA	leucine-rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]	2.88	2.79	4.81	7.6	8.7	8.97	0.48	-1.05	0.04	0.32	down	yes
MSTRG.25255	ARMC10	MSTRG.25255.1;ENST00000425331;ENST00000541300;ENST00000428183;ENST00000441711;ENST00000454559;ENST00000323716;MSTRG.25255.8;ENST00000323735;ENST00000306450;ENST00000434153;MSTRG.25255.12;ENST00000431642;ENST00000479145	GO:0005488(binding);GO:0005739(mitochondrion);GO:0005789(endoplasmic reticulum membrane);GO:0016021(integral component of membrane);GO:0040008(regulation of growth)	NA	NA	NA	armadillo repeat containing 10 [Source:HGNC Symbol;Acc:HGNC:21706]	14.19	11.69	10.48	5.62	6	5.42	2.08	1.06	0.01	0.2	up	yes
MSTRG.25261	DPY19L2P2	ENST00000439473;ENST00000438364;ENST00000411491;ENST00000312132;MSTRG.25261.6;MSTRG.25261.7;ENST00000446373	NA	NA	NA	NA	NA	0.13	0.24	0.26	1.88	1.62	0.77	0.44	-1.19	0.02	0.25	down	yes
MSTRG.25274	EIF4BP6	ENST00000431936	NA	NA	NA	NA	NA	3.35	0	0.34	0	0.35	1.94	2.49	1.32	0.03	0.3	up	yes
MSTRG.25307	NAMPT	ENST00000222553;MSTRG.25307.2;MSTRG.25307.1;MSTRG.25307.3;MSTRG.25307.4;ENST00000463871;ENST00000354289;ENST00000491027;ENST00000467730;ENST00000484527;ENST00000393618;ENST00000441045;ENST00000486949;ENST00000489358;ENST00000424768;ENST00000489732;ENST00000417537	GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006766(vitamin metabolic process);GO:0006767(water-soluble vitamin metabolic process);GO:0006769(nicotinamide metabolic process);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0008144(drug binding);GO:0008284(positive regulation of cell proliferation);GO:0009435(NAD biosynthetic process);GO:0014070(response to organic cyclic compound);GO:0019674(NAD metabolic process);GO:0032922(circadian regulation of gene expression);GO:0042803(protein homodimerization activity);GO:0044281(small molecule metabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0070062(extracellular exosome)	00760(Nicotinate and nicotinamide metabolism)	K00763	6.3.4.21	nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]	87.49	90.6	171.66	10.15	8.27	5.63	10.74	3.42	0.01	0.2	up	yes
MSTRG.25314	HBP1	ENST00000468410;MSTRG.25314.2;MSTRG.25314.3;MSTRG.25314.5;MSTRG.25314.4;ENST00000478930;ENST00000464009;ENST00000222574;ENST00000468401;ENST00000468116;ENST00000497535;ENST00000485846;ENST00000479011;ENST00000463202;ENST00000498408;ENST00000461963;ENST00000483809;ENST00000607681;ENST00000463790	"GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007050(cell cycle arrest);GO:0016055(Wnt signaling pathway);GO:0043268(positive regulation of potassium ion transport)"	NA	NA	NA	HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]	19.39	15.57	12.99	4.19	3.53	8.16	3.44	1.78	0.02	0.27	up	yes
MSTRG.25316	COG5	ENST00000347053;ENST00000297135;ENST00000393603;ENST00000464542;ENST00000468350;ENST00000462342;MSTRG.25316.7;ENST00000484237;ENST00000605888;ENST00000469503	GO:0000139(Golgi membrane);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0015031(protein transport);GO:0016020(membrane);GO:0017119(Golgi transport complex)	NA	NA	NA	component of oligomeric golgi complex 5 [Source:HGNC Symbol;Acc:HGNC:14857]	9.93	13.29	14.59	2.84	2.47	2.39	3.31	1.73	0	0.14	up	yes
MSTRG.25334	DNAJB9	ENST00000249356;ENST00000491582;ENST00000465725	GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response);GO:0044267(cellular protein metabolic process);GO:0051787(misfolded protein binding);GO:0070062(extracellular exosome)	NA	NA	NA	"DnaJ (Hsp40) homolog, subfamily B, member 9 [Source:HGNC Symbol;Acc:HGNC:6968]"	57.3	40.99	27.77	3.42	3.75	3.15	10.51	3.39	0	0.17	up	yes
MSTRG.25344	ZNF277	ENST00000361822;ENST00000361946;ENST00000421043;ENST00000457808;MSTRG.25344.3;ENST00000425229;ENST00000450657;ENST00000421864	"GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0070301(cellular response to hydrogen peroxide);GO:2000772(regulation of cellular senescence)"	NA	NA	NA	zinc finger protein 277 [Source:HGNC Symbol;Acc:HGNC:13070]	6.39	7.7	4.81	1.68	1.47	1.69	2.63	1.4	0.01	0.23	up	yes
MSTRG.25351	LSMEM1	ENST00000432734;ENST00000005558;ENST00000621379;ENST00000445335;ENST00000417662;ENST00000403825;ENST00000429071;ENST00000476927;ENST00000440625;ENST00000535603;ENST00000466459;ENST00000421296;ENST00000489994;ENST00000470441;ENST00000462155;ENST00000455302;ENST00000312849;ENST00000486022;ENST00000471030	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016021(integral component of membrane)	NA	NA	NA	leucine-rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:22036]	19.72	18.97	14.41	4.67	5.57	2.98	3.33	1.74	0.02	0.25	up	yes
MSTRG.25384	FAM3C	MSTRG.25384.1;ENST00000359943;MSTRG.25384.3;ENST00000474082;ENST00000412653;ENST00000426156;ENST00000497622	GO:0005125(cytokine activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005794(Golgi apparatus);GO:0007275(multicellular organismal development);GO:0008150(biological_process);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0070062(extracellular exosome)	NA	NA	NA	"family with sequence similarity 3, member C [Source:HGNC Symbol;Acc:HGNC:18664]"	15.89	19.07	8.49	53.55	48.39	31.42	0.28	-1.82	0.04	0.32	down	yes
MSTRG.25388	PTPRZ1	ENST00000393386;MSTRG.25388.2;ENST00000449182;ENST00000483028;ENST00000489114;ENST00000483995;ENST00000468641;ENST00000474500	GO:0002244(hematopoietic progenitor cell differentiation);GO:0004725(protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005578(proteinaceous extracellular matrix);GO:0005887(integral component of plasma membrane);GO:0006470(protein dephosphorylation);GO:0007409(axonogenesis);GO:0007417(central nervous system development);GO:0007611(learning or memory);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0048709(oligodendrocyte differentiation);GO:0070445(regulation of oligodendrocyte progenitor proliferation);GO:0072534(perineuronal net)	05120(Epithelial cell signaling in Helicobacter pylori infection)	NA	NA	"protein tyrosine phosphatase, receptor-type, Z polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:9685]"	1.12	1.69	0.91	5.36	3.85	7.52	0.34	-1.56	0.03	0.29	down	yes
MSTRG.25412	.	MSTRG.25412.1	NA	NA	NA	NA	NA	0.11	0.48	0.27	1.81	1.13	1.1	0.46	-1.12	0	0.13	down	yes
MSTRG.25417	GCC1	MSTRG.25417.1;ENST00000321407;ENST00000497650;ENST00000473728	GO:0000042(protein targeting to Golgi);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane)	NA	NA	NA	GRIP and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19095]	6.19	2.58	6.31	0.06	0.1	0.02	6.75	2.75	0.01	0.19	up	yes
MSTRG.25419	GRM8	ENST00000339582;ENST00000358373;ENST00000489939;ENST00000341617;ENST00000495315;ENST00000472701;ENST00000480995;ENST00000465844;ENST00000412160	"GO:0001642(group III metabotropic glutamate receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007196(adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway);GO:0007601(visual perception);GO:0007608(sensory perception of smell);GO:0008066(glutamate receptor activity);GO:0016021(integral component of membrane);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0042734(presynaptic membrane);GO:0051966(regulation of synaptic transmission, glutamatergic)"	04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse)	NA	NA	"glutamate receptor, metabotropic 8 [Source:HGNC Symbol;Acc:HGNC:4600]"	0.32	0.49	0.32	3.58	2.96	3.6	0.27	-1.87	0	0.12	down	yes
MSTRG.2544	CENPF	ENST00000464322;ENST00000366955;ENST00000495259;ENST00000614578;ENST00000467765;ENST00000469862	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000785(chromatin);GO:0000922(spindle pole);GO:0000940(condensed chromosome outer kinetochore);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007094(mitotic spindle assembly checkpoint);GO:0007264(small GTPase mediated signal transduction);GO:0007517(muscle organ development);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0008283(cell proliferation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0015031(protein transport);GO:0016202(regulation of striated muscle tissue development);GO:0016363(nuclear matrix);GO:0030154(cell differentiation);GO:0030496(midbody);GO:0042493(response to drug);GO:0042803(protein homodimerization activity);GO:0045120(pronucleus);GO:0045502(dynein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048471(perinuclear region of cytoplasm);GO:0051301(cell division);GO:0051310(metaphase plate congression);GO:0051382(kinetochore assembly);GO:0051726(regulation of cell cycle);GO:0071897(DNA biosynthetic process)"	NA	NA	NA	"centromere protein F, 350/400kDa [Source:HGNC Symbol;Acc:HGNC:1857]"	1.16	0.98	0.5	24.21	18.17	3.33	0.1	-3.34	0.05	0.34	down	yes
MSTRG.25472	ZC3HC1	ENST00000358303;ENST00000311873;ENST00000360708;ENST00000467642;MSTRG.25472.5;ENST00000481503;ENST00000477578;ENST00000471022;ENST00000483827;ENST00000480193;ENST00000470651;ENST00000484432	GO:0005515(protein binding);GO:0005634(nucleus);GO:0007067(mitotic nuclear division);GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0019901(protein kinase binding);GO:0031965(nuclear membrane);GO:0051301(cell division);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)	NA	NA	NA	"zinc finger, C3HC-type containing 1 [Source:HGNC Symbol;Acc:HGNC:29913]"	5.04	6.57	7.66	13.17	13.21	9.48	0.49	-1.03	0.02	0.25	down	yes
MSTRG.25490	PODXL	ENST00000446198;ENST00000484346;ENST00000378555;ENST00000322985;ENST00000490761;ENST00000487965;ENST00000482581;ENST00000465001	GO:0001726(ruffle);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007162(negative regulation of cell adhesion);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0022407(regulation of cell-cell adhesion);GO:0022408(negative regulation of cell-cell adhesion);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030335(positive regulation of cell migration);GO:0031528(microvillus membrane);GO:0032534(regulation of microvillus assembly);GO:0033634(positive regulation of cell-cell adhesion mediated by integrin);GO:0036057(slit diaphragm);GO:0044297(cell body);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072015(glomerular visceral epithelial cell development);GO:0072175(epithelial tube formation)	NA	NA	NA	podocalyxin-like [Source:HGNC Symbol;Acc:HGNC:9171]	3.97	2.08	2.07	13.6	9.08	24.35	0.31	-1.7	0.05	0.33	down	yes
MSTRG.25501	LINC-PINT	ENST00000423414;MSTRG.25501.2;MSTRG.25501.3;MSTRG.25501.4;ENST00000433079;ENST00000451786;ENST00000443623;ENST00000435523;ENST00000431189;ENST00000416999	NA	NA	NA	NA	NA	4.19	4.2	3.49	0.67	0.51	0.63	3.07	1.62	0	0.13	up	yes
MSTRG.25526	C7orf49	ENST00000459937;ENST00000464070;MSTRG.25526.3;MSTRG.25526.4;ENST00000620897;ENST00000617987;ENST00000424142;ENST00000393114;ENST00000481410;ENST00000483029;ENST00000472428;ENST00000477820;ENST00000488161;ENST00000487774;ENST00000486115	GO:0005515(protein binding);GO:0005737(cytoplasm)	NA	NA	NA	chromosome 7 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:22432]	2.23	2.64	4.34	9.56	9.17	6.56	0.37	-1.43	0.02	0.27	down	yes
MSTRG.25528	TMEM140	ENST00000275767	GO:0005515(protein binding);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870]	2.94	4.37	4.34	9.35	8.63	7.17	0.43	-1.22	0	0.14	down	yes
MSTRG.25551	PTN	ENST00000348225;MSTRG.25551.1;ENST00000393083	GO:0001503(ossification);GO:0001889(liver development);GO:0004864(protein phosphatase inhibitor activity);GO:0005539(glycosaminoglycan binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway);GO:0007399(nervous system development);GO:0007420(brain development);GO:0007528(neuromuscular junction development);GO:0007612(learning);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0008284(positive regulation of cell proliferation);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010976(positive regulation of neuron projection development);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0016020(membrane);GO:0021510(spinal cord development);GO:0030282(bone mineralization);GO:0030324(lung development);GO:0030902(hindbrain development);GO:0035373(chondroitin sulfate proteoglycan binding);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042493(response to drug);GO:0043086(negative regulation of catalytic activity);GO:0045837(negative regulation of membrane potential);GO:0048471(perinuclear region of cytoplasm);GO:0051781(positive regulation of cell division);GO:0060041(retina development in camera-type eye);GO:0060221(retinal rod cell differentiation);GO:0060291(long-term synaptic potentiation);GO:0071305(cellular response to vitamin D);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0071456(cellular response to hypoxia);GO:1990089(response to nerve growth factor);GO:2000347(positive regulation of hepatocyte proliferation)	NA	NA	NA	pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630]	11.88	11.84	3.37	58.36	59.53	62.77	0.16	-2.69	0.04	0.31	down	yes
MSTRG.25575	TBXAS1	ENST00000493340;ENST00000462053;ENST00000473948;ENST00000425687;ENST00000263552;ENST00000416849;ENST00000474763;ENST00000481440;ENST00000438104;ENST00000336425;ENST00000414508;MSTRG.25575.12;ENST00000448866;ENST00000422328;ENST00000492560;ENST00000455353;ENST00000411653;ENST00000476637;ENST00000462275;ENST00000469630;ENST00000494876	"GO:0004497(monooxygenase activity);GO:0004796(thromboxane-A synthase activity);GO:0005506(iron ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0006690(icosanoid metabolic process);GO:0006805(xenobiotic metabolic process);GO:0016021(integral component of membrane);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0019369(arachidonic acid metabolic process);GO:0019371(cyclooxygenase pathway);GO:0020037(heme binding);GO:0030644(cellular chloride ion homeostasis);GO:0044281(small molecule metabolic process);GO:0045907(positive regulation of vasoconstriction);GO:0055114(oxidation-reduction process)"	00590(Arachidonic acid metabolism);01100(Metabolic pathways)	NA	NA	thromboxane A synthase 1 (platelet) [Source:HGNC Symbol;Acc:HGNC:11609]	0.44	0.22	0.33	1.71	1.69	2.97	0.5	-1.01	0.02	0.25	down	yes
MSTRG.25576	TBXAS1	MSTRG.25576.1	NA	NA	NA	NA	NA	1.6	1.46	1.19	0.05	0.03	0.06	2.36	1.24	0	0.14	up	yes
MSTRG.25592	BRAF	ENST00000496384;MSTRG.25592.3;MSTRG.25592.2;MSTRG.25592.4;ENST00000288602;ENST00000479537;ENST00000497784;ENST00000469930	"GO:0000165(MAPK cascade);GO:0000186(activation of MAPKK activity);GO:0002318(myeloid progenitor cell differentiation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004709(MAP kinase kinase kinase activity);GO:0005057(receptor signaling protein activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007268(synaptic transmission);GO:0008542(visual learning);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009887(organ morphogenesis);GO:0010628(positive regulation of gene expression);GO:0010764(negative regulation of fibroblast migration);GO:0015758(glucose transport);GO:0016020(membrane);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030154(cell differentiation);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035019(somatic stem cell maintenance);GO:0035556(intracellular signal transduction);GO:0035690(cellular response to drug);GO:0042127(regulation of cell proliferation);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043368(positive T cell selection);GO:0043434(response to peptide hormone);GO:0043524(negative regulation of neuron apoptotic process);GO:0044297(cell body);GO:0046632(alpha-beta T cell differentiation);GO:0046982(protein heterodimerization activity);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048679(regulation of axon regeneration);GO:0048680(positive regulation of axon regeneration);GO:0050772(positive regulation of axonogenesis);GO:0051291(protein heterooligomerization);GO:0051496(positive regulation of stress fiber assembly);GO:0051591(response to cAMP);GO:0060291(long-term synaptic potentiation);GO:0060323(head morphogenesis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071277(cellular response to calcium ion);GO:0090150(establishment of protein localization to membrane);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000352(negative regulation of endothelial cell apoptotic process)"	04010(MAPK signaling pathway);04012(ErbB signaling pathway);04062(Chemokine signaling pathway);04150(mTOR signaling pathway);04270(Vascular smooth muscle contraction);04510(Focal adhesion);04650(Natural killer cell mediated cytotoxicity);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04730(Long-term depression);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04914(Progesterone-mediated oocyte maturation);05160(Hepatitis C);05200(Pathways in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05213(Endometrial cancer);05214(Glioma);05215(Prostate cancer);05216(Thyroid cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer)	NA	NA	"B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097]"	6.51	8.71	4.94	2.59	1.93	1.8	2.13	1.09	0.03	0.28	up	yes
MSTRG.25642	CNTNAP2	MSTRG.25642.1	NA	NA	NA	NA	NA	0.98	1.49	1.95	0.04	0.11	0	2.12	1.08	0.01	0.24	up	yes
MSTRG.25687	TMUB1	ENST00000297533;ENST00000392818;ENST00000462940;ENST00000482202;ENST00000476627;ENST00000492838	GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process)	NA	NA	NA	transmembrane and ubiquitin-like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21709]	25.32	19.36	23.86	10.68	11.01	13.05	2.15	1.11	0	0.14	up	yes
MSTRG.25696	NUB1	MSTRG.25696.1;MSTRG.25696.4;MSTRG.25696.2;MSTRG.25696.3;ENST00000413040;MSTRG.25696.7;MSTRG.25696.6;ENST00000568733;MSTRG.25696.9;MSTRG.25696.10;MSTRG.25696.12;MSTRG.25696.11;MSTRG.25696.13;ENST00000468404;ENST00000470229;ENST00000483358;ENST00000470316;ENST00000493588;ENST00000480907;ENST00000477666;ENST00000497987;ENST00000460712;ENST00000480714	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm)	NA	NA	NA	negative regulator of ubiquitin-like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623]	19.83	19.09	20.39	9.41	10.03	8.19	2.01	1.01	0	0.17	up	yes
MSTRG.25708	.	MSTRG.25708.1	NA	NA	NA	NA	NA	0.17	0.33	0.2	3.2	2.07	0.75	0.34	-1.57	0.03	0.29	down	yes
MSTRG.25720	INSIG1	ENST00000340368;ENST00000425172;MSTRG.25720.3;MSTRG.25720.5;ENST00000342407;ENST00000476756;ENST00000468307	GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006641(triglyceride metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0006991(response to sterol depletion);GO:0008152(metabolic process);GO:0008203(cholesterol metabolic process);GO:0008283(cell proliferation);GO:0010894(negative regulation of steroid biosynthetic process);GO:0016021(integral component of membrane);GO:0016126(sterol biosynthetic process);GO:0032933(SREBP signaling pathway);GO:0032937(SREBP-SCAP-Insig complex);GO:0042472(inner ear morphogenesis);GO:0042474(middle ear morphogenesis);GO:0044281(small molecule metabolic process);GO:0045599(negative regulation of fat cell differentiation);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0060021(palate development);GO:0060363(cranial suture morphogenesis);GO:1901303(negative regulation of cargo loading into COPII-coated vesicle)	NA	NA	NA	insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083]	70.62	49.4	42.82	11.34	5.29	5.31	6.47	2.69	0.02	0.25	up	yes
MSTRG.25756	NCAPG2	MSTRG.25756.1;ENST00000432615;ENST00000356309;ENST00000409423;MSTRG.25756.5;ENST00000441982;ENST00000467785;ENST00000409339;ENST00000474940;ENST00000475918;ENST00000491792;ENST00000621338	GO:0000278(mitotic cell cycle);GO:0001833(inner cell mass cell proliferation);GO:0005488(binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007067(mitotic nuclear division);GO:0016020(membrane);GO:0030261(chromosome condensation);GO:0035064(methylated histone binding);GO:0051301(cell division)	NA	NA	NA	"non-SMC condensin II complex, subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904]"	3.79	3.65	2.36	24.31	24.34	7.76	0.19	-2.4	0.04	0.33	down	yes
MSTRG.25776	CLN8	MSTRG.25776.1;ENST00000518780;ENST00000517514;ENST00000331222;ENST00000520991;ENST00000519254;ENST00000523237	GO:0001306(age-dependent response to oxidative stress);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0006644(phospholipid metabolic process);GO:0006672(ceramide metabolic process);GO:0006869(lipid transport);GO:0007006(mitochondrial membrane organization);GO:0007040(lysosome organization);GO:0007399(nervous system development);GO:0007601(visual perception);GO:0007628(adult walking behavior);GO:0008203(cholesterol metabolic process);GO:0008306(associative learning);GO:0008344(adult locomotory behavior);GO:0008361(regulation of cell size);GO:0008610(lipid biosynthetic process);GO:0016021(integral component of membrane);GO:0021522(spinal cord motor neuron differentiation);GO:0021523(somatic motor neuron differentiation);GO:0030163(protein catabolic process);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0035176(social behavior);GO:0043066(negative regulation of apoptotic process);GO:0044257(cellular protein catabolic process);GO:0044265(cellular macromolecule catabolic process);GO:0044267(cellular protein metabolic process);GO:0045494(photoreceptor cell maintenance);GO:0045861(negative regulation of proteolysis);GO:0046513(ceramide biosynthetic process);GO:0050881(musculoskeletal movement);GO:0050884(neuromuscular process controlling posture);GO:0050885(neuromuscular process controlling balance);GO:0051935(L-glutamate uptake involved in synaptic transmission);GO:0060041(retina development in camera-type eye);GO:0060052(neurofilament cytoskeleton organization)	NA	NA	NA	"ceroid-lipofuscinosis, neuronal 8 [Source:HGNC Symbol;Acc:HGNC:2079]"	4.05	3.53	3.78	1.41	1.39	0.79	2.13	1.09	0.01	0.24	up	yes
MSTRG.2581	DUSP10	ENST00000366899;ENST00000468085;MSTRG.2581.2;ENST00000477026	GO:0000188(inactivation of MAPK activity);GO:0002819(regulation of adaptive immune response);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0006470(protein dephosphorylation);GO:0006950(response to stress);GO:0007254(JNK cascade);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0010033(response to organic substance);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0032496(response to lipopolysaccharide);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0033549(MAP kinase phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0043508(negative regulation of JUN kinase activity);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0045088(regulation of innate immune response);GO:0046329(negative regulation of JNK cascade);GO:0048709(oligodendrocyte differentiation);GO:0048715(negative regulation of oligodendrocyte differentiation);GO:0060266(negative regulation of respiratory burst involved in inflammatory response);GO:0090335(regulation of brown fat cell differentiation)	04010(MAPK signaling pathway)	NA	NA	dual specificity phosphatase 10 [Source:HGNC Symbol;Acc:HGNC:3065]	8.63	6.53	5.34	3.01	1.77	1.48	2.49	1.32	0.04	0.33	up	yes
MSTRG.25843	LONRF1	ENST00000398246;ENST00000526680;MSTRG.25843.2;ENST00000527055;ENST00000525024;ENST00000533751;ENST00000524526;ENST00000526610;ENST00000534446;ENST00000530693	GO:0004176(ATP-dependent peptidase activity);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0008270(zinc ion binding)	NA	NA	NA	LON peptidase N-terminal domain and ring finger 1 [Source:HGNC Symbol;Acc:HGNC:26302]	4.21	3.75	4.46	1.16	0.92	0.74	2.58	1.37	0	0.17	up	yes
MSTRG.25882	CSGALNACT1	ENST00000454498;ENST00000332246;ENST00000397998;MSTRG.25882.2;MSTRG.25882.1;MSTRG.25882.7;MSTRG.25882.6;MSTRG.25882.8;ENST00000522854;ENST00000518542;ENST00000519222;ENST00000523262;ENST00000517494;ENST00000524213;ENST00000517651;ENST00000523227;ENST00000522732;ENST00000522573;ENST00000523919;ENST00000524112	"GO:0000139(Golgi membrane);GO:0001958(endochondral ossification);GO:0005622(intracellular);GO:0005975(carbohydrate metabolic process);GO:0007399(nervous system development);GO:0008037(cell recognition);GO:0008283(cell proliferation);GO:0008376(acetylgalactosaminyltransferase activity);GO:0008955(peptidoglycan glycosyltransferase activity);GO:0009653(anatomical structure morphogenesis);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0015020(glucuronosyltransferase activity);GO:0019276(UDP-N-acetylgalactosamine metabolic process);GO:0030166(proteoglycan biosynthetic process);GO:0030173(integral component of Golgi membrane);GO:0030198(extracellular matrix organization);GO:0030203(glycosaminoglycan metabolic process);GO:0030204(chondroitin sulfate metabolic process);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030210(heparin biosynthetic process);GO:0032580(Golgi cisterna membrane);GO:0044281(small molecule metabolic process);GO:0046398(UDP-glucuronate metabolic process);GO:0046872(metal ion binding);GO:0047237(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity);GO:0047238(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity);GO:0050650(chondroitin sulfate proteoglycan biosynthetic process);GO:0050651(dermatan sulfate proteoglycan biosynthetic process);GO:0050653(chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0051216(cartilage development)"	00532(Glycosaminoglycan biosynthesis - chondroitin sulfate);01100(Metabolic pathways)	NA	NA	chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24290]	1.74	2.19	1.71	6.19	4.28	9.1	0.4	-1.32	0.05	0.33	down	yes
MSTRG.25891	FAM160B2	MSTRG.25891.1	NA	NA	NA	NA	NA	1.54	1.3	1.14	0	0.26	0.3	2.2	1.14	0	0.17	up	yes
MSTRG.25894	REEP4	ENST00000334530;MSTRG.25894.1;ENST00000306306;MSTRG.25894.4;ENST00000523293;ENST00000518664;ENST00000519074;ENST00000519875;ENST00000521744	GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005874(microtubule);GO:0006998(nuclear envelope organization);GO:0007067(mitotic nuclear division);GO:0007084(mitotic nuclear envelope reassembly);GO:0008017(microtubule binding);GO:0016021(integral component of membrane);GO:0051301(cell division)	NA	NA	NA	receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176]	5.12	4.18	4.78	17.88	18.78	11.21	0.33	-1.61	0.02	0.25	down	yes
MSTRG.25897	POLR3D	ENST00000306433;ENST00000519237;ENST00000397802;ENST00000518039;ENST00000517789	GO:0000790(nuclear chromatin);GO:0001056(RNA polymerase III activity);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003899(DNA-directed RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006383(transcription from RNA polymerase III promoter);GO:0006385(transcription elongation from RNA polymerase III promoter);GO:0006386(termination of RNA polymerase III transcription);GO:0010467(gene expression);GO:0032481(positive regulation of type I interferon production);GO:0032728(positive regulation of interferon-beta production);GO:0045087(innate immune response);GO:0045089(positive regulation of innate immune response);GO:0051607(defense response to virus)	00230(Purine metabolism);00240(Pyrimidine metabolism);01100(Metabolic pathways);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway)	NA	NA	"polymerase (RNA) III (DNA directed) polypeptide D, 44kDa [Source:HGNC Symbol;Acc:HGNC:1080]"	18.06	21.05	20.95	5.43	7.09	10.15	2.74	1.46	0.02	0.26	up	yes
MSTRG.25901	PPP3CC	ENST00000518852;MSTRG.25901.1;MSTRG.25901.3;ENST00000240139;ENST00000289963;ENST00000397775;ENST00000522000;ENST00000522034;ENST00000521651;ENST00000523620	GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0008152(metabolic process);GO:0012501(programmed cell death);GO:0016311(dephosphorylation);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0070062(extracellular exosome);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)	04010(MAPK signaling pathway);04020(Calcium signaling pathway);04114(Oocyte meiosis);04210(Apoptosis);04310(Wnt signaling pathway);04360(Axon guidance);04370(VEGF signaling pathway);04380(Osteoclast differentiation);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04720(Long-term potentiation);04724(Glutamatergic synapse);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05152(Tuberculosis)	NA	NA	"protein phosphatase 3, catalytic subunit, gamma isozyme [Source:HGNC Symbol;Acc:HGNC:9316]"	9.63	9.3	9.65	2.65	2.85	2.51	2.88	1.53	0	0.08	up	yes
MSTRG.25919	TNFRSF10B	MSTRG.25919.1;ENST00000523752;ENST00000276431;ENST00000347739;ENST00000523504;ENST00000520109;ENST00000518531;ENST00000519910;ENST00000519028	GO:0004872(receptor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009986(cell surface);GO:0010939(regulation of necrotic cell death);GO:0012501(programmed cell death);GO:0016021(integral component of membrane);GO:0034976(response to endoplasmic reticulum stress);GO:0042981(regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045569(TRAIL binding);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0070266(necroptotic process);GO:0071260(cellular response to mechanical stimulus);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0097300(programmed necrotic cell death);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors)	04060(Cytokine-cytokine receptor interaction);04115(p53 signaling pathway);04210(Apoptosis);04650(Natural killer cell mediated cytotoxicity);05162(Measles);05164(Influenza A)	NA	NA	"tumor necrosis factor receptor superfamily, member 10b [Source:HGNC Symbol;Acc:HGNC:11905]"	63.25	64	46.6	10.08	13.4	10.47	4.91	2.3	0	0.17	up	yes
MSTRG.25925	ENTPD4	MSTRG.25925.1;ENST00000389131;ENST00000520617;ENST00000520349;ENST00000518878;ENST00000522446;ENST00000519809;ENST00000520925;ENST00000518472;ENST00000524144;ENST00000518083;ENST00000524168;ENST00000519243;ENST00000518471;ENST00000356206;ENST00000521321;ENST00000524075;MSTRG.25925.20;MSTRG.25925.21;MSTRG.25925.22;ENST00000358689;ENST00000522255;ENST00000417069;ENST00000523958;ENST00000522913;ENST00000520936;ENST00000519839;ENST00000518718	GO:0000421(autophagosome membrane);GO:0006256(UDP catabolic process);GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0030173(integral component of Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0045134(uridine-diphosphatase activity)	00230(Purine metabolism);00240(Pyrimidine metabolism);04142(Lysosome)	NA	NA	ectonucleoside triphosphate diphosphohydrolase 4 [Source:HGNC Symbol;Acc:HGNC:14573]	8.05	6.3	5.69	25.87	19.18	28.69	0.33	-1.6	0.01	0.23	down	yes
MSTRG.25929	SLC25A37	ENST00000519973;ENST00000417331;ENST00000290075;ENST00000518881;ENST00000519192;ENST00000520654;ENST00000523930;ENST00000523883;ENST00000517923;ENST00000520949;ENST00000522164;ENST00000521637	GO:0005381(iron ion transmembrane transporter activity);GO:0005743(mitochondrial inner membrane);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0034755(iron ion transmembrane transport);GO:0044281(small molecule metabolic process);GO:0048250(mitochondrial iron ion transport);GO:0055072(iron ion homeostasis)	NA	NA	NA	"solute carrier family 25 (mitochondrial iron transporter), member 37 [Source:HGNC Symbol;Acc:HGNC:29786]"	12.74	11.57	14.67	3.75	4.93	6.66	2.69	1.43	0.01	0.22	up	yes
MSTRG.25949	SCARA3	ENST00000301904	GO:0000139(Golgi membrane);GO:0005044(scavenger receptor activity);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005789(endoplasmic reticulum membrane);GO:0006898(receptor-mediated endocytosis);GO:0006979(response to oxidative stress);GO:0009650(UV protection);GO:0016021(integral component of membrane)	NA	NA	NA	"scavenger receptor class A, member 3 [Source:HGNC Symbol;Acc:HGNC:19000]"	0.18	0.25	0.04	1.6	1.51	0.64	0.43	-1.21	0.03	0.28	down	yes
MSTRG.25958	ESCO2	ENST00000523566;ENST00000305188;ENST00000522378;ENST00000519637;ENST00000524293;ENST00000518262;ENST00000397418	"GO:0000278(mitotic cell cycle);GO:0000785(chromatin);GO:0001741(XY body);GO:0002244(hematopoietic progenitor cell differentiation);GO:0004468(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0006275(regulation of DNA replication);GO:0006302(double-strand break repair);GO:0007059(chromosome segregation);GO:0010369(chromocenter);GO:0031618(nuclear pericentric heterochromatin);GO:0034421(post-translational protein acetylation);GO:0035861(site of double-strand break);GO:0046872(metal ion binding);GO:0071168(protein localization to chromatin)"	NA	NA	NA	establishment of sister chromatid cohesion N-acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:27230]	0.07	0.09	0.04	2.47	2.36	0.69	0.33	-1.59	0.03	0.3	down	yes
MSTRG.25961	PBK	MSTRG.25961.1;ENST00000301905;ENST00000522944;ENST00000524266;ENST00000521226	"GO:0001933(negative regulation of protein phosphorylation);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005575(cellular_component);GO:0005634(nucleus);GO:0006468(protein phosphorylation);GO:0007067(mitotic nuclear division);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0034644(cellular response to UV);GO:0050728(negative regulation of inflammatory response)"	NA	NA	NA	PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282]	5.19	5.23	1.87	49.14	64.99	17.44	0.1	-3.31	0.04	0.31	down	yes
MSTRG.2599	.	MSTRG.2599.1	NA	NA	NA	NA	NA	7.42	4.21	3.31	1.7	1.47	2.23	2.56	1.36	0.03	0.28	up	yes
MSTRG.26051	PPAPDC1B	ENST00000529359;ENST00000424479;MSTRG.26051.1;ENST00000530193;MSTRG.26051.5;MSTRG.26051.6;ENST00000530432;ENST00000524616;ENST00000531823;ENST00000534339;ENST00000531109;ENST00000527758;ENST00000422581;ENST00000531483;ENST00000419686;ENST00000528814;ENST00000524409	GO:0003824(catalytic activity);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0008195(phosphatidate phosphatase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046839(phospholipid dephosphorylation)	NA	NA	NA	phosphatidic acid phosphatase type 2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:25026]	6.46	5.01	7.91	2.23	2.46	1.11	2.49	1.31	0.05	0.33	up	yes
MSTRG.26068	TM2D2	ENST00000456845;ENST00000456397;MSTRG.26068.3;ENST00000397070;ENST00000522434;ENST00000522142;ENST00000521060;ENST00000524331;ENST00000519186;ENST00000517872	GO:0016021(integral component of membrane)	NA	NA	NA	TM2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24127]	2.4	2.74	2.38	6.48	8.46	4.92	0.43	-1.2	0.02	0.27	down	yes
MSTRG.26076	GINS4	MSTRG.26076.1;MSTRG.26076.2;ENST00000276533;ENST00000520354;ENST00000520710;MSTRG.26076.5;ENST00000520631;ENST00000520736;ENST00000518671;ENST00000523277;ENST00000522642;ENST00000518430	GO:0000278(mitotic cell cycle);GO:0000727(double-strand break repair via break-induced replication);GO:0000811(GINS complex);GO:0001833(inner cell mass cell proliferation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0031298(replication fork protection complex);GO:0032508(DNA duplex unwinding);GO:0043138(3'-5' DNA helicase activity)	NA	NA	NA	GINS complex subunit 4 (Sld5 homolog) [Source:HGNC Symbol;Acc:HGNC:28226]	0.41	0.45	0.33	7.07	6.42	2.25	0.19	-2.38	0.02	0.26	down	yes
MSTRG.26091	THAP1	ENST00000254250;ENST00000345117;ENST00000532093	"GO:0001935(endothelial cell proliferation);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007049(cell cycle);GO:0007346(regulation of mitotic cell cycle);GO:0008270(zinc ion binding);GO:0016605(PML body);GO:0042802(identical protein binding);GO:0043565(sequence-specific DNA binding)"	NA	NA	NA	"THAP domain containing, apoptosis associated protein 1 [Source:HGNC Symbol;Acc:HGNC:20856]"	6.95	1.43	4.86	0.53	0.79	1.51	4.28	2.1	0.01	0.22	up	yes
MSTRG.26103	ASNSP1	MSTRG.26103.1;MSTRG.26103.2;MSTRG.26103.3;ENST00000518311;MSTRG.26103.5;MSTRG.26103.6;MSTRG.26103.7;MSTRG.26103.8	NA	NA	NA	NA	NA	4.24	4.93	5.83	0.17	0.03	0.09	5.06	2.34	0	0.11	up	yes
MSTRG.26116	PRKDC	ENST00000314191;MSTRG.26116.3;MSTRG.26116.2;MSTRG.26116.4;MSTRG.26116.5;MSTRG.26116.6;MSTRG.26116.7;ENST00000338368;ENST00000536429;ENST00000536483;ENST00000521331;ENST00000536710;ENST00000432581;ENST00000546304;ENST00000541488;ENST00000535375;ENST00000540819	"GO:0000723(telomere maintenance);GO:0000724(double-strand break repair via homologous recombination);GO:0001756(somitogenesis);GO:0001933(negative regulation of protein phosphorylation);GO:0002326(B cell lineage commitment);GO:0002328(pro-B cell differentiation);GO:0002360(T cell lineage commitment);GO:0002377(immunoglobulin production);GO:0002638(negative regulation of immunoglobulin production);GO:0002684(positive regulation of immune system process);GO:0003677(DNA binding);GO:0003690(double-stranded DNA binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004677(DNA-dependent protein kinase activity);GO:0005488(binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006464(cellular protein modification process);GO:0007420(brain development);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010212(response to ionizing radiation);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0016020(membrane);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0018105(peptidyl-serine phosphorylation);GO:0019899(enzyme binding);GO:0030098(lymphocyte differentiation);GO:0031648(protein destabilization);GO:0032481(positive regulation of type I interferon production);GO:0032869(cellular response to insulin stimulus);GO:0033077(T cell differentiation in thymus);GO:0033151(V(D)J recombination);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0035234(ectopic germ cell programmed cell death);GO:0042752(regulation of circadian rhythm);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048146(positive regulation of fibroblast proliferation);GO:0048511(rhythmic process);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048639(positive regulation of developmental growth);GO:0070419(nonhomologous end joining complex);GO:0072431(signal transduction involved in mitotic G1 DNA damage checkpoint);GO:2000773(negative regulation of cellular senescence);GO:2001229(negative regulation of response to gamma radiation)"	03450(Non-homologous end-joining);04110(Cell cycle)	NA	NA	"protein kinase, DNA-activated, catalytic polypeptide [Source:HGNC Symbol;Acc:HGNC:9413]"	10.13	12.19	14.09	32.03	27.65	18.42	0.41	-1.3	0.02	0.25	down	yes
MSTRG.26119	MCM4	ENST00000518221;MSTRG.26119.2;ENST00000523944;MSTRG.26119.4;ENST00000262105;ENST00000520934;ENST00000524086;ENST00000519138;ENST00000520637;ENST00000518680;ENST00000517709;ENST00000519470;ENST00000523853;ENST00000518382;ENST00000521261;ENST00000521151	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0016020(membrane);GO:0042555(MCM complex)	03030(DNA replication);04110(Cell cycle)	NA	NA	minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947]	4.68	6.54	4.53	35.74	33.85	22.04	0.16	-2.61	0	0.15	down	yes
MSTRG.26131	TCEA1	MSTRG.26131.1;ENST00000396401;ENST00000521604;ENST00000521086;ENST00000522635;ENST00000522397;ENST00000520534;ENST00000518310;ENST00000517351;ENST00000521836;ENST00000518784;ENST00000519704	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003746(translation elongation factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006289(nucleotide-excision repair);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006414(translational elongation);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016032(viral process);GO:0030218(erythrocyte differentiation);GO:0032784(regulation of DNA-templated transcription, elongation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:1901919(positive regulation of exoribonuclease activity)"	NA	NA	NA	"transcription elongation factor A (SII), 1 [Source:HGNC Symbol;Acc:HGNC:11612]"	61.57	149.42	121.81	42.52	18.29	21.2	2.38	1.25	0.02	0.27	up	yes
MSTRG.26135	RP11-53M11.3	MSTRG.26135.1;ENST00000522711;ENST00000518787;ENST00000522001	NA	NA	NA	NA	NA	1.39	1.96	2.34	0.03	0.27	0.34	2.36	1.24	0.02	0.26	up	yes
MSTRG.26154	SDCBP	ENST00000522243;ENST00000260130;ENST00000447182;ENST00000413219;ENST00000424270;ENST00000523483;ENST00000520168;ENST00000519115;ENST00000522843;MSTRG.26154.10;ENST00000630925;ENST00000447267;ENST00000520228;ENST00000523441	"GO:0001948(glycoprotein binding);GO:0005109(frizzled binding);GO:0005137(interleukin-5 receptor binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0005895(interleukin-5 receptor complex);GO:0005912(adherens junction);GO:0005925(focal adhesion);GO:0006612(protein targeting to membrane);GO:0006930(substrate-dependent cell migration, cell extension);GO:0007265(Ras protein signal transduction);GO:0007268(synaptic transmission);GO:0007411(axon guidance);GO:0008022(protein C-terminus binding);GO:0008093(cytoskeletal adaptor activity);GO:0016020(membrane);GO:0019838(growth factor binding);GO:0030036(actin cytoskeleton organization);GO:0035556(intracellular signal transduction);GO:0042043(neurexin family protein binding);GO:0042327(positive regulation of phosphorylation);GO:0042470(melanosome);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045545(syndecan binding);GO:0046330(positive regulation of JNK cascade);GO:0046875(ephrin receptor binding);GO:0046982(protein heterodimerization activity);GO:0047485(protein N-terminus binding);GO:0048013(ephrin receptor signaling pathway);GO:0050839(cell adhesion molecule binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:1903561(extracellular vesicle)"	NA	NA	NA	syndecan binding protein (syntenin) [Source:HGNC Symbol;Acc:HGNC:10662]	111.32	112.86	69.43	17.79	15.88	13.55	5.51	2.46	0.01	0.2	up	yes
MSTRG.26164	CHD7	MSTRG.26164.1	NA	NA	NA	NA	NA	1.52	0.98	0.51	0.04	0.02	0.02	2.09	1.07	0.03	0.3	up	yes
MSTRG.26176	GGH	ENST00000518466;ENST00000260118;ENST00000522852;ENST00000520609;ENST00000518113;ENST00000518966;ENST00000523479;ENST00000523788	GO:0003824(catalytic activity);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005764(lysosome);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006541(glutamine metabolic process);GO:0008238(exopeptidase activity);GO:0008242(omega peptidase activity);GO:0010043(response to zinc ion);GO:0016787(hydrolase activity);GO:0032868(response to insulin);GO:0034722(gamma-glutamyl-peptidase activity);GO:0042470(melanosome);GO:0042493(response to drug);GO:0045471(response to ethanol);GO:0070062(extracellular exosome)	00790(Folate biosynthesis)	NA	NA	"gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) [Source:HGNC Symbol;Acc:HGNC:4248]"	12.1	15.51	7.48	36.02	32.89	21.89	0.34	-1.58	0.04	0.32	down	yes
MSTRG.26180	CYP7B1	ENST00000523954;ENST00000310193	"GO:0005506(iron ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0006699(bile acid biosynthetic process);GO:0006805(xenobiotic metabolic process);GO:0008203(cholesterol metabolic process);GO:0008206(bile acid metabolic process);GO:0008396(oxysterol 7-alpha-hydroxylase activity);GO:0016125(sterol metabolic process);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0033783(25-hydroxycholesterol 7alpha-hydroxylase activity);GO:0044281(small molecule metabolic process);GO:0050679(positive regulation of epithelial cell proliferation);GO:0055114(oxidation-reduction process);GO:0060740(prostate gland epithelium morphogenesis)"	00120(Primary bile acid biosynthesis);00140(Steroid hormone biosynthesis)	NA	NA	"cytochrome P450, family 7, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:2652]"	1.45	1.15	1.13	5.48	4.38	2.96	0.4	-1.32	0.02	0.27	down	yes
MSTRG.26184	ARMC1	ENST00000276569;ENST00000518908;ENST00000519352	GO:0005488(binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0030001(metal ion transport);GO:0046872(metal ion binding)	NA	NA	NA	armadillo repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:17684]	3.6	4.57	4.47	19.36	16.65	5.7	0.28	-1.85	0.05	0.34	down	yes
MSTRG.26213	SLCO5A1	MSTRG.26213.1	NA	NA	NA	NA	NA	1.34	0.38	0.6	0	0.11	0	2.02	1.01	0.02	0.25	up	yes
MSTRG.26253	CRISPLD1	ENST00000262207;ENST00000519798	GO:0003674(molecular_function);GO:0005576(extracellular region);GO:0060325(face morphogenesis);GO:0070062(extracellular exosome)	NA	NA	NA	cysteine-rich secretory protein LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18206]	1.51	1.28	1.04	4.26	4.07	3.09	0.46	-1.13	0.01	0.23	down	yes
MSTRG.26270	HEY1	ENST00000354724;ENST00000337919;ENST00000435063;ENST00000523976;ENST00000518733;ENST00000521111;ENST00000519075;ENST00000523531	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000983(RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity);GO:0000988(protein binding transcription factor activity);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0002076(osteoblast development);GO:0003184(pulmonary valve morphogenesis);GO:0003190(atrioventricular valve formation);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003199(endocardial cushion to mesenchymal transition involved in heart valve formation);GO:0003203(endocardial cushion morphogenesis);GO:0003208(cardiac ventricle morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007219(Notch signaling pathway);GO:0008134(transcription factor binding);GO:0009948(anterior/posterior axis specification);GO:0010629(negative regulation of gene expression);GO:0035912(dorsal aorta morphogenesis);GO:0035939(microsatellite binding);GO:0036304(umbilical cord morphogenesis);GO:0043565(sequence-specific DNA binding);GO:0045669(positive regulation of osteoblast differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046983(protein dimerization activity);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0060347(heart trabecula formation);GO:0060411(cardiac septum morphogenesis);GO:0060412(ventricular septum morphogenesis);GO:0060716(labyrinthine layer blood vessel development);GO:0060840(artery development);GO:0060842(arterial endothelial cell differentiation);GO:0061314(Notch signaling involved in heart development);GO:0071385(cellular response to glucocorticoid stimulus);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:2000820(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation);GO:2001212(regulation of vasculogenesis)"	NA	NA	NA	hes-related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880]	34.07	31.43	14.17	1.64	4.92	10.42	7.11	2.83	0.04	0.33	up	yes
MSTRG.26292	FTH1P11	ENST00000517577	NA	NA	NA	NA	NA	1.57	1.71	2.01	0.24	0.26	0.46	2.12	1.09	0	0.18	up	yes
MSTRG.26300	ZFAND1	MSTRG.26300.1;MSTRG.26300.2;MSTRG.26300.3;ENST00000524305;ENST00000523096;ENST00000220669;ENST00000522520;ENST00000519338;ENST00000522032;ENST00000519464;ENST00000521895;ENST00000521287;ENST00000523431;ENST00000520635;ENST00000517588;ENST00000519523;ENST00000520604;ENST00000523361;ENST00000517450;ENST00000521742;ENST00000518419;ENST00000520076;ENST00000524339;ENST00000517353;ENST00000519820;ENST00000521885;ENST00000523012	GO:0008270(zinc ion binding)	NA	NA	NA	"zinc finger, AN1-type domain 1 [Source:HGNC Symbol;Acc:HGNC:25858]"	9.41	12.41	6.94	3	2.85	2.25	2.49	1.31	0.02	0.27	up	yes
MSTRG.26301	CHMP4C	ENST00000297265	GO:0000920(cell separation after cytokinesis);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006997(nucleus organization);GO:0007034(vacuolar transport);GO:0007080(mitotic metaphase plate congression);GO:0009838(abscission);GO:0010824(regulation of centrosome duplication);GO:0015031(protein transport);GO:0016032(viral process);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0030496(midbody);GO:0031902(late endosome membrane);GO:0032466(negative regulation of cytokinesis);GO:0042803(protein homodimerization activity);GO:0050792(regulation of viral process);GO:0061024(membrane organization);GO:0070062(extracellular exosome);GO:0090543(Flemming body);GO:0090611(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway);GO:1901673(regulation of mitotic spindle assembly);GO:1902188(positive regulation of viral release from host cell)	04144(Endocytosis)	NA	NA	charged multivesicular body protein 4C [Source:HGNC Symbol;Acc:HGNC:30599]	3.25	4.07	4.73	1.2	0.84	1.04	2.24	1.16	0.01	0.2	up	yes
MSTRG.26321	ATP6V0D2	ENST00000521564;MSTRG.26321.2;ENST00000285393	"GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0006879(cellular iron ion homeostasis);GO:0008286(insulin receptor signaling pathway);GO:0010008(endosome membrane);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016020(membrane);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0030670(phagocytic vesicle membrane);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0033572(transferrin transport);GO:0034220(ion transmembrane transport);GO:0051701(interaction with host);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0090382(phagosome maturation)"	00190(Oxidative phosphorylation);01100(Metabolic pathways);04142(Lysosome);04145(Phagosome);04966(Collecting duct acid secretion);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05323(Rheumatoid arthritis)	NA	NA	"ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 [Source:HGNC Symbol;Acc:HGNC:18266]"	4.43	4.35	6.91	0.01	0.07	0	5.9	2.56	0	0.17	up	yes
MSTRG.26345	RIPK2	ENST00000220751;MSTRG.26345.2;ENST00000522965;ENST00000517696;ENST00000518673	"GO:0000187(activation of MAPK activity);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0002224(toll-like receptor signaling pathway);GO:0002250(adaptive immune response);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0002827(positive regulation of T-helper 1 type immune response);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0004871(signal transducer activity);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007254(JNK cascade);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030274(LIM domain binding);GO:0031398(positive regulation of protein ubiquitination);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0031982(vesicle);GO:0032722(positive regulation of chemokine production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032729(positive regulation of interferon-gamma production);GO:0032735(positive regulation of interleukin-12 production);GO:0032743(positive regulation of interleukin-2 production);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0033091(positive regulation of immature T cell proliferation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0042098(T cell proliferation);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043234(protein complex);GO:0043330(response to exogenous dsRNA);GO:0045087(innate immune response);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046330(positive regulation of JNK cascade);GO:0046641(positive regulation of alpha-beta T cell proliferation);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050700(CARD domain binding);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050830(defense response to Gram-positive bacterium);GO:0050852(T cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0070427(nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0070555(response to interleukin-1);GO:0070671(response to interleukin-12);GO:0070673(response to interleukin-18);GO:0071222(cellular response to lipopolysaccharide);GO:0071223(cellular response to lipoteichoic acid);GO:0071224(cellular response to peptidoglycan);GO:0071225(cellular response to muramyl dipeptide)"	04621(NOD-like receptor signaling pathway);04722(Neurotrophin signaling pathway);05131(Shigellosis);05152(Tuberculosis)	NA	NA	receptor-interacting serine-threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020]	21.28	17.81	17.63	6.04	6.7	3.37	3.06	1.62	0.02	0.27	up	yes
MSTRG.26347	OSGIN2	MSTRG.26347.1;ENST00000297438;ENST00000451899;ENST00000520659	GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0051321(meiotic cell cycle)	NA	NA	NA	oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355]	19.68	18.03	14.21	3.76	1.3	3.39	4.91	2.29	0.02	0.27	up	yes
MSTRG.26357	TMEM55A	ENST00000285419;ENST00000520709;ENST00000518359;ENST00000520014;ENST00000518869	GO:0005765(lysosomal membrane);GO:0008152(metabolic process);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0031902(late endosome membrane)	NA	NA	NA	transmembrane protein 55A [Source:HGNC Symbol;Acc:HGNC:25452]	22.9	19.05	11.96	5.24	2.79	4.45	3.72	1.9	0.03	0.29	up	yes
MSTRG.26390	ESRP1	MSTRG.26390.1;ENST00000423620;ENST00000433389;ENST00000358397;ENST00000454170;ENST00000520385;ENST00000522920;ENST00000522756;ENST00000519505;ENST00000517610;ENST00000517556;ENST00000523347	GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0043484(regulation of RNA splicing)	NA	NA	NA	epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]	2.47	2.72	1.9	0.32	0.26	0.41	2.5	1.32	0	0.18	up	yes
MSTRG.2640	PARP1	ENST00000366794;ENST00000490921;ENST00000463968;ENST00000491816;ENST00000468608;ENST00000498787;ENST00000469663;ENST00000366792;ENST00000366790	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0006259(DNA metabolic process);GO:0006281(DNA repair);GO:0006284(base-excision repair);GO:0006302(double-strand break repair);GO:0006351(transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006471(protein ADP-ribosylation);GO:0007005(mitochondrion organization);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016020(membrane);GO:0016540(protein autoprocessing);GO:0016925(protein sumoylation);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030225(macrophage differentiation);GO:0032042(mitochondrial DNA metabolic process);GO:0032869(cellular response to insulin stimulus);GO:0034599(cellular response to oxidative stress);GO:0036211(protein modification process);GO:0040009(regulation of growth rate);GO:0042769(DNA damage response, detection of DNA damage);GO:0042802(identical protein binding);GO:0043234(protein complex);GO:0043504(mitochondrial DNA repair);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0047485(protein N-terminus binding);GO:0048148(behavioral response to cocaine);GO:0051287(NAD binding);GO:0060391(positive regulation of SMAD protein import into nucleus);GO:0070212(protein poly-ADP-ribosylation);GO:0070412(R-SMAD binding);GO:0071451(cellular response to superoxide);GO:1903516(regulation of single strand break repair);GO:2000679(positive regulation of transcription regulatory region DNA binding)"	03410(Base excision repair)	NA	NA	poly (ADP-ribose) polymerase 1 [Source:HGNC Symbol;Acc:HGNC:270]	22.76	25.25	22.91	59.77	64.3	66.53	0.38	-1.4	0	0.12	down	yes
MSTRG.26422	KB-1208A12.3	ENST00000501016	NA	NA	NA	NA	NA	5.1	3.26	2.84	1.18	1.16	1.26	2.43	1.28	0.01	0.22	up	yes
MSTRG.26425	POP1	ENST00000522319;MSTRG.26425.2;ENST00000401707;ENST00000349693;ENST00000517435	"GO:0000171(ribonuclease MRP activity);GO:0000172(ribonuclease MRP complex);GO:0001682(tRNA 5'-leader removal);GO:0004526(ribonuclease P activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005655(nucleolar ribonuclease P complex);GO:0006396(RNA processing);GO:0008033(tRNA processing);GO:0016078(tRNA catabolic process);GO:0044822(poly(A) RNA binding);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)"	03008(Ribosome biogenesis in eukaryotes);03013(RNA transport)	NA	NA	"processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:30129]"	0.77	1.03	1.75	14.72	16.13	8.07	0.13	-2.91	0.01	0.2	down	yes
MSTRG.26530	SYBU	ENST00000533895;ENST00000424158;ENST00000532779;ENST00000399066;ENST00000529175;ENST00000276646;ENST00000408908;ENST00000422135;ENST00000533065;ENST00000529690;ENST00000527707;ENST00000528045;ENST00000528735;ENST00000528569;ENST00000532189;ENST00000526736;ENST00000530841;ENST00000531284;ENST00000524720	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0016021(integral component of membrane);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0017075(syntaxin-1 binding);GO:0019894(kinesin binding);GO:0031982(vesicle);GO:0043231(intracellular membrane-bounded organelle);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0097433(dense body)	NA	NA	NA	syntabulin (syntaxin-interacting) [Source:HGNC Symbol;Acc:HGNC:26011]	2.76	2.55	1.89	0.3	0.37	0.48	2.65	1.41	0	0.17	up	yes
MSTRG.26533	.	MSTRG.26533.1	NA	NA	NA	NA	NA	0.84	1.27	1.06	3.82	1.65	2.15	0.49	-1.03	0.03	0.3	down	yes
MSTRG.26545	NOV	ENST00000259526;ENST00000520082	GO:0001558(regulation of cell growth);GO:0005178(integrin binding);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0010468(regulation of gene expression);GO:0030424(axon);GO:0030425(dendrite);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0060548(negative regulation of cell death)	NA	NA	NA	nephroblastoma overexpressed [Source:HGNC Symbol;Acc:HGNC:7885]	18.05	11.58	6.3	1.72	0.83	0.96	6.05	2.6	0.03	0.28	up	yes
MSTRG.26559	MRPL13	ENST00000521648;ENST00000518696;ENST00000522717;ENST00000306185;ENST00000613356;ENST00000518918;ENST00000520677	GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0006996(organelle organization);GO:0032543(mitochondrial translation);GO:0044822(poly(A) RNA binding);GO:0070124(mitochondrial translational initiation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)	03010(Ribosome)	NA	NA	mitochondrial ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:14278]	5.36	7.74	6.76	14.69	13.26	8.9	0.46	-1.11	0.01	0.2	down	yes
MSTRG.26560	MTBP	ENST00000522308;ENST00000523373;ENST00000305949;ENST00000522449;ENST00000519188;ENST00000519556	GO:0000776(kinetochore);GO:0000785(chromatin);GO:0005515(protein binding);GO:0007050(cell cycle arrest);GO:0007089(traversing start control point of mitotic cell cycle);GO:0008285(negative regulation of cell proliferation);GO:0034501(protein localization to kinetochore);GO:0045839(negative regulation of mitotic nuclear division)	NA	NA	NA	MDM2 binding protein [Source:HGNC Symbol;Acc:HGNC:7417]	0.26	0.41	0.39	2.14	1.78	0.59	0.45	-1.15	0.04	0.33	down	yes
MSTRG.26568	ZHX2	ENST00000314393;MSTRG.26568.2;ENST00000534247	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006402(mRNA catabolic process);GO:0035019(somatic stem cell maintenance);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045665(negative regulation of neuron differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0046982(protein heterodimerization activity)"	NA	NA	NA	zinc fingers and homeoboxes 2 [Source:HGNC Symbol;Acc:HGNC:18513]	5.15	9.29	8.03	2.45	2.13	2.57	2.06	1.04	0.02	0.26	up	yes
MSTRG.26608	FAM84B	MSTRG.26608.1;ENST00000304916;MSTRG.26608.3	NA	NA	NA	NA	NA	5.79	10.17	10.96	18.39	19	14.11	0.42	-1.24	0.02	0.25	down	yes
MSTRG.26615	PVT1	MSTRG.26615.1;MSTRG.26615.3;MSTRG.26615.4;MSTRG.26615.2;MSTRG.26615.5;MSTRG.26615.6;MSTRG.26615.7;MSTRG.26615.8;ENST00000504719;ENST00000523328;ENST00000524165;ENST00000521951;ENST00000517525;ENST00000523427;MSTRG.26615.16;ENST00000517790;ENST00000522963;ENST00000518528;ENST00000523068;ENST00000521122;ENST00000615442;ENST00000513868;ENST00000520913;ENST00000519481;ENST00000517838;ENST00000612011;ENST00000512617;ENST00000521600;ENST00000522875;ENST00000523190;ENST00000616386;ENST00000613916;ENST00000522414	NA	NA	NA	NA	NA	4.38	3.49	3.46	1.23	1.11	1.09	2.33	1.22	0	0.15	up	yes
MSTRG.26641	ST3GAL1	ENST00000399640;MSTRG.26641.1;ENST00000521180;MSTRG.26641.4;MSTRG.26641.5;ENST00000522652;ENST00000523854;ENST00000517668;ENST00000522204;MSTRG.26641.10;ENST00000523634;ENST00000523855;ENST00000519435;ENST00000518298;ENST00000520020;ENST00000522873;ENST00000521627;ENST00000522285	"GO:0000139(Golgi membrane);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006054(N-acetylneuraminate metabolic process);GO:0006464(cellular protein modification process);GO:0006468(protein phosphorylation);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006493(protein O-linked glycosylation);GO:0008373(sialyltransferase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030173(integral component of Golgi membrane);GO:0030203(glycosaminoglycan metabolic process);GO:0032580(Golgi cisterna membrane);GO:0042339(keratan sulfate metabolic process);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0070062(extracellular exosome);GO:0097503(sialylation)"	00512(Mucin type O-Glycan biosynthesis);00533(Glycosaminoglycan biosynthesis - keratan sulfate);00603(Glycosphingolipid biosynthesis - globo series);00604(Glycosphingolipid biosynthesis - ganglio series);01100(Metabolic pathways)	NA	NA	"ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862]"	13.32	12.04	13.72	1.18	2.29	4.37	5.39	2.43	0.01	0.22	up	yes
MSTRG.26670	ARC	ENST00000356613;ENST00000581404	GO:0001669(acrosomal vesicle);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0007010(cytoskeleton organization);GO:0007492(endoderm development);GO:0007612(learning);GO:0009952(anterior/posterior pattern specification);GO:0014069(postsynaptic density);GO:0015629(actin cytoskeleton);GO:0016477(cell migration);GO:0022604(regulation of cell morphogenesis);GO:0030054(cell junction);GO:0043197(dendritic spine);GO:0045211(postsynaptic membrane);GO:0048168(regulation of neuronal synaptic plasticity);GO:2000969(positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity)	NA	NA	NA	activity-regulated cytoskeleton-associated protein [Source:HGNC Symbol;Acc:HGNC:648]	3.04	2.78	2.51	0.49	0.55	0.42	2.58	1.37	0	0.12	up	yes
MSTRG.26721	HGH1	ENST00000347708;ENST00000530074;ENST00000530409;ENST00000525101;ENST00000534255	GO:0003674(molecular_function);GO:0005488(binding);GO:0005575(cellular_component);GO:0008150(biological_process)	NA	NA	NA	HGH1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:24161]	0.83	0.87	1.01	6.5	3.01	1.72	0.33	-1.59	0.05	0.33	down	yes
MSTRG.26727	HSF1	MSTRG.26727.1;ENST00000528838;MSTRG.26727.4;ENST00000528988;ENST00000533240;ENST00000532338;ENST00000528199;ENST00000529630;ENST00000534314;ENST00000527328;ENST00000531447;ENST00000533130;ENST00000614796;ENST00000528842	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding);GO:0001701(in utero embryonic development);GO:0001892(embryonic placenta development);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006952(defense response);GO:0007143(female meiotic division);GO:0007283(spermatogenesis);GO:0008285(negative regulation of cell proliferation);GO:0009299(mRNA transcription);GO:0009408(response to heat);GO:0032496(response to lipopolysaccharide);GO:0032720(negative regulation of tumor necrosis factor production);GO:0034605(cellular response to heat);GO:0040018(positive regulation of multicellular organism growth);GO:0043234(protein complex);GO:0043565(sequence-specific DNA binding);GO:0045120(pronucleus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060136(embryonic process involved in female pregnancy);GO:1900034(regulation of cellular response to heat)"	NA	NA	NA	heat shock transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5224]	13.53	10.1	12.25	5.62	6.16	8.08	2.02	1.01	0	0.17	up	yes
MSTRG.26736	TONSL	ENST00000497613;ENST00000409379;ENST00000613741	GO:0000724(double-strand break repair via homologous recombination);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005662(DNA replication factor A complex);GO:0005737(cytoplasm);GO:0031297(replication fork processing);GO:0035101(FACT complex);GO:0042393(histone binding);GO:0042555(MCM complex);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0043596(nuclear replication fork);GO:1903507(negative regulation of nucleic acid-templated transcription)	NA	NA	NA	"tonsoku-like, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:7801]"	0.54	0.4	0.41	2.55	3.38	2.34	0.4	-1.32	0.01	0.19	down	yes
MSTRG.26741	KIFC2	ENST00000301332;MSTRG.26741.2;ENST00000529644;ENST00000533114;ENST00000529864;ENST00000531425;ENST00000531423	GO:0003777(microtubule motor activity);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0016887(ATPase activity)	NA	NA	NA	kinesin family member C2 [Source:HGNC Symbol;Acc:HGNC:29530]	6.5	6.11	4.05	0.8	1.73	2.57	3.07	1.62	0.03	0.28	up	yes
MSTRG.26748	RECQL4	ENST00000621189;ENST00000617875;ENST00000531875;ENST00000529424;ENST00000534626;ENST00000532846;MSTRG.26748.8;ENST00000524998;ENST00000534538;ENST00000534270	GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0006310(DNA recombination);GO:0008026(ATP-dependent helicase activity);GO:0008270(zinc ion binding)	NA	NA	NA	RecQ protein-like 4 [Source:HGNC Symbol;Acc:HGNC:9949]	1.87	2.25	3.14	10.98	11.25	7.85	0.27	-1.87	0.01	0.19	down	yes
MSTRG.26756	ZNF34	ENST00000343459;ENST00000429371;ENST00000527740;MSTRG.26756.4;ENST00000534337;ENST00000534445	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger protein 34 [Source:HGNC Symbol;Acc:HGNC:13098]	3.32	2.86	1.8	0.14	0.47	1.7	2.84	1.51	0.05	0.34	up	yes
MSTRG.2676	HIST3H2BB	ENST00000620438;MSTRG.2676.2	NA	NA	NA	NA	NA	1.98	0.73	0.5	0.07	0.13	0.13	2.21	1.15	0.04	0.31	up	yes
MSTRG.26775	KANK1	ENST00000382303;ENST00000467541;ENST00000489369;ENST00000354485;MSTRG.26775.10;MSTRG.26775.11;ENST00000382293;ENST00000382289;ENST00000382286	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008013(beta-catenin binding);GO:0010977(negative regulation of neuron projection development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0030336(negative regulation of cell migration);GO:0030837(negative regulation of actin filament polymerization);GO:0032587(ruffle membrane);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035413(positive regulation of catenin import into nucleus);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0090303(positive regulation of wound healing);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1900028(negative regulation of ruffle assembly);GO:2000114(regulation of establishment of cell polarity);GO:2000393(negative regulation of lamellipodium morphogenesis)"	NA	NA	NA	KN motif and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:19309]	10.24	8.54	7.22	4.14	3.09	4.51	2.12	1.09	0.02	0.27	up	yes
MSTRG.26803	CDC37L1	ENST00000381858;ENST00000381854;ENST00000479095	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006457(protein folding);GO:0031072(heat shock protein binding);GO:0050821(protein stabilization);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding)	NA	NA	NA	cell division cycle 37-like 1 [Source:HGNC Symbol;Acc:HGNC:17179]	8.32	9.38	7.32	3.54	3.04	2.5	2.11	1.08	0.01	0.2	up	yes
MSTRG.26827	RP11-574F11.3	MSTRG.26827.1	NA	NA	NA	NA	NA	2.13	1.71	1.63	0.56	0.16	0.66	2.05	1.04	0.02	0.28	up	yes
MSTRG.2683	RHOU	ENST00000366691	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000139(Golgi membrane);GO:0002102(podosome);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007010(cytoskeleton organization);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0008360(regulation of cell shape);GO:0015031(protein transport);GO:0016020(membrane);GO:0016601(Rac protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:0042995(cell projection);GO:0046872(metal ion binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:1903955(positive regulation of protein targeting to mitochondrion)	NA	NA	NA	ras homolog family member U [Source:HGNC Symbol;Acc:HGNC:17794]	1.68	1.42	1.75	6.69	5.18	6.49	0.37	-1.42	0	0.17	down	yes
MSTRG.26842	RP11-390F4.6	ENST00000413145	NA	NA	NA	NA	NA	2.07	2.25	1.65	0.31	0.27	0.23	2.28	1.19	0	0.17	up	yes
MSTRG.26869	LURAP1L	MSTRG.26869.1;ENST00000319264;ENST00000489107	NA	NA	NA	NA	leucine rich adaptor protein 1-like [Source:HGNC Symbol;Acc:HGNC:31452]	3.3	3.27	2.59	0.25	0.13	0.22	3.37	1.75	0	0.13	up	yes
MSTRG.26903	RPS6	ENST00000380394;ENST00000498815;ENST00000380384;ENST00000315377;ENST00000380381	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0001890(placenta development);GO:0002309(T cell proliferation involved in immune response);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005844(polysome);GO:0006364(rRNA processing);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006924(activation-induced cell death of T cells);GO:0007067(mitotic nuclear division);GO:0007093(mitotic cell cycle checkpoint);GO:0007369(gastrulation);GO:0008286(insulin receptor signaling pathway);GO:0010467(gene expression);GO:0015935(small ribosomal subunit);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019901(protein kinase binding);GO:0022605(oogenesis stage);GO:0022627(cytosolic small ribosomal subunit);GO:0030425(dendrite);GO:0030529(ribonucleoprotein complex);GO:0031929(TOR signaling);GO:0033077(T cell differentiation in thymus);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0042274(ribosomal small subunit biogenesis);GO:0042593(glucose homeostasis);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0044267(cellular protein metabolic process);GO:0044297(cell body);GO:0044822(poly(A) RNA binding);GO:0048471(perinuclear region of cytoplasm);GO:0048821(erythrocyte development)"	03010(Ribosome);04150(mTOR signaling pathway);04910(Insulin signaling pathway)	NA	NA	ribosomal protein S6 [Source:HGNC Symbol;Acc:HGNC:10429]	909.14	943.72	890.7	420.45	473.01	608.81	2	1	0.02	0.25	up	yes
MSTRG.26922	MIR31HG	ENST00000304425;MSTRG.26922.2	NA	NA	NA	NA	NA	0.7	1.25	1.3	3.8	2.87	3.24	0.42	-1.26	0	0.17	down	yes
MSTRG.26924	MIR31HG	MSTRG.26924.1	NA	NA	NA	NA	NA	0.42	0.7	0.85	4.38	2.89	2.42	0.33	-1.61	0	0.17	down	yes
MSTRG.26927	CDKN2B-AS1	ENST00000380172;ENST00000404796;ENST00000460874;ENST00000580675;ENST00000580900;ENST00000580718;ENST00000579422;ENST00000427788;ENST00000577563;ENST00000584988;ENST00000581962;ENST00000484957;ENST00000584351;ENST00000585267;ENST00000580576;ENST00000428597;ENST00000582301;ENST00000581051;ENST00000582072;ENST00000455933;ENST00000421632	NA	NA	NA	NA	NA	0.61	1.81	0.63	3.36	3.56	2.45	0.37	-1.45	0.01	0.24	down	yes
MSTRG.26938	RP11-370B11.3	MSTRG.26938.1;MSTRG.26938.3;MSTRG.26938.4;MSTRG.26938.2;MSTRG.26938.5;MSTRG.26938.6;MSTRG.26938.7;MSTRG.26938.8;ENST00000325870;ENST00000436786;ENST00000433645;ENST00000448570	NA	NA	NA	NA	NA	3.17	3.05	3.69	0.61	0.57	0.93	2.65	1.41	0	0.17	up	yes
MSTRG.26940	LINC01239	MSTRG.26940.1	NA	NA	NA	NA	NA	1.4	1.13	1.23	0.14	0.09	0.37	2.05	1.04	0	0.17	up	yes
MSTRG.26974	BAG1	ENST00000493917;ENST00000472232;ENST00000379701;ENST00000467389;ENST00000379707;ENST00000379704;ENST00000468274;ENST00000473464;ENST00000473781;ENST00000488499	GO:0001933(negative regulation of protein phosphorylation);GO:0005057(receptor signaling protein activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0030182(neuron differentiation);GO:0034605(cellular response to heat);GO:0035556(intracellular signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051087(chaperone binding);GO:0051219(phosphoprotein binding);GO:0070389(chaperone cofactor-dependent protein refolding);GO:0070585(protein localization to mitochondrion);GO:1900034(regulation of cellular response to heat);GO:2000672(negative regulation of motor neuron apoptotic process)	04141(Protein processing in endoplasmic reticulum)	NA	NA	BCL2-associated athanogene [Source:HGNC Symbol;Acc:HGNC:937]	14.34	14.84	11	4.36	5.36	6.63	2.45	1.29	0.01	0.24	up	yes
MSTRG.270	NPPA-AS1	ENST00000312413;ENST00000346436;ENST00000376497;ENST00000376496;ENST00000376490;ENST00000376491;ENST00000376492;ENST00000494028;ENST00000446542;ENST00000400892	NA	NA	NA	NA	NA	5.12	5.67	4.71	1.46	1.16	1.61	2.52	1.33	0	0.17	up	yes
MSTRG.2700	COG2	ENST00000494371;ENST00000366669;ENST00000468893;ENST00000366668;ENST00000534989;ENST00000482012;ENST00000490900;ENST00000478710	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005795(Golgi stack);GO:0005829(cytosol);GO:0006486(protein glycosylation);GO:0006886(intracellular protein transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0007030(Golgi organization);GO:0008565(protein transporter activity);GO:0009312(oligosaccharide biosynthetic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0017119(Golgi transport complex);GO:0032403(protein complex binding)	NA	NA	NA	component of oligomeric golgi complex 2 [Source:HGNC Symbol;Acc:HGNC:6546]	1.11	1.79	2.28	4.61	4.51	3.96	0.44	-1.19	0.01	0.23	down	yes
MSTRG.27002	KIF24	ENST00000379174;ENST00000379166	GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005814(centriole);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0006996(organelle organization);GO:0007018(microtubule-based movement);GO:0007019(microtubule depolymerization);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0016887(ATPase activity);GO:0042384(cilium assembly);GO:0043234(protein complex)	NA	NA	NA	kinesin family member 24 [Source:HGNC Symbol;Acc:HGNC:19916]	0.15	0.17	0.2	3.3	2.94	1.58	0.29	-1.78	0.01	0.2	down	yes
MSTRG.27022	FANCG	MSTRG.27022.1;MSTRG.27022.2;ENST00000425676;ENST00000378643;MSTRG.27022.5;MSTRG.27022.6;MSTRG.27022.7;ENST00000481254;ENST00000474894;ENST00000448890;ENST00000461149;ENST00000462124	GO:0000075(cell cycle checkpoint);GO:0001541(ovarian follicle development);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007005(mitochondrion organization);GO:0007286(spermatid development);GO:0009314(response to radiation);GO:0043240(Fanconi anaemia nuclear complex)	NA	NA	NA	"Fanconi anemia, complementation group G [Source:HGNC Symbol;Acc:HGNC:3588]"	2.05	2.6	1.74	9.71	9.15	6.77	0.29	-1.79	0	0.17	down	yes
MSTRG.27026	FAM214B	MSTRG.27026.1;ENST00000378566;MSTRG.27026.3;ENST00000603301;ENST00000488109;ENST00000322813;ENST00000605244;ENST00000378561;ENST00000378557;ENST00000605104;ENST00000605392	GO:0005515(protein binding);GO:0005634(nucleus)	NA	NA	NA	"family with sequence similarity 214, member B [Source:HGNC Symbol;Acc:HGNC:25666]"	8.47	6.55	8.07	2.16	1.74	3.02	3	1.59	0.01	0.19	up	yes
MSTRG.27037	CCDC107	ENST00000378409;ENST00000378407;ENST00000378406;ENST00000426546;ENST00000327351;ENST00000421582	GO:0016021(integral component of membrane)	NA	NA	NA	coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465]	10.11	8.08	5.39	2.87	2.45	4.74	2.41	1.27	0.05	0.34	up	yes
MSTRG.27038	ARHGEF39	ENST00000490638;MSTRG.27038.3;MSTRG.27038.2;MSTRG.27038.4;ENST00000475323;ENST00000378387;ENST00000490970;ENST00000488918;ENST00000468876	GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0030335(positive regulation of cell migration);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity)	NA	NA	NA	Rho guanine nucleotide exchange factor (GEF) 39 [Source:HGNC Symbol;Acc:HGNC:25909]	0.17	0.16	0.2	3.75	4.89	1.41	0.25	-2	0.03	0.29	down	yes
MSTRG.27055	TMEM8B	ENST00000377996;ENST00000439587;ENST00000377991;MSTRG.27055.4;ENST00000464519;ENST00000377988;ENST00000473947;ENST00000490199	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0007160(cell-matrix adhesion);GO:0007346(regulation of mitotic cell cycle);GO:0009986(cell surface);GO:0016021(integral component of membrane);GO:0040008(regulation of growth)	NA	NA	NA	transmembrane protein 8B [Source:HGNC Symbol;Acc:HGNC:21427]	3.67	2.91	1.72	0.57	0.51	1.03	2.49	1.32	0.03	0.29	up	yes
MSTRG.27067	MELK	ENST00000298048;ENST00000536329;ENST00000536860;ENST00000541717;ENST00000543751;ENST00000627766;MSTRG.27067.7;MSTRG.27067.8;MSTRG.27067.9;MSTRG.27067.10;MSTRG.27067.11;MSTRG.27067.12;MSTRG.27067.13;ENST00000536987;ENST00000495529;ENST00000545008;ENST00000625974;ENST00000487398;ENST00000626154;MSTRG.27067.21;ENST00000480021	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0008283(cell proliferation);GO:0008289(lipid binding);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0016020(membrane);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0061351(neural precursor cell proliferation)"	NA	NA	NA	maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870]	5.21	6.73	3.67	34.47	33.26	10.94	0.18	-2.46	0.04	0.3	down	yes
MSTRG.27086	DCAF10	ENST00000377724;ENST00000242323;MSTRG.27086.3;MSTRG.27086.4;ENST00000461549;ENST00000483167;ENST00000478453	GO:0005515(protein binding);GO:0016567(protein ubiquitination);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)	NA	NA	NA	DDB1 and CUL4 associated factor 10 [Source:HGNC Symbol;Acc:HGNC:23686]	6.24	2.87	7.17	1.03	1.22	1.78	3.47	1.79	0.01	0.24	up	yes
MSTRG.27091	ALDH1B1	ENST00000377698;MSTRG.27091.2	NA	NA	NA	NA	NA	2.73	4.13	4.35	8.67	9.01	10.81	0.42	-1.26	0.02	0.25	down	yes
MSTRG.27098	GLIDR	MSTRG.27098.1;ENST00000625350;ENST00000618092;ENST00000627065	NA	NA	NA	NA	NA	0.14	0.15	0.25	1.7	2.13	1.49	0.42	-1.26	0	0.17	down	yes
MSTRG.2711	EGLN1	MSTRG.2711.1;MSTRG.2711.2;ENST00000366641;ENST00000476717	"GO:0001666(response to hypoxia);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:0019899(enzyme binding);GO:0030821(negative regulation of cAMP catabolic process);GO:0031418(L-ascorbic acid binding);GO:0031543(peptidyl-proline dioxygenase activity);GO:0031545(peptidyl-proline 4-dioxygenase activity);GO:0032364(oxygen homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045765(regulation of angiogenesis);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0055008(cardiac muscle tissue morphogenesis);GO:0055114(oxidation-reduction process);GO:0060347(heart trabecula formation);GO:0060412(ventricular septum morphogenesis);GO:0060711(labyrinthine layer development);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0071456(cellular response to hypoxia);GO:0071731(response to nitric oxide)"	05200(Pathways in cancer);05211(Renal cell carcinoma)	NA	NA	egl-9 family hypoxia-inducible factor 1 [Source:HGNC Symbol;Acc:HGNC:1232]	6.84	4.61	5.14	2.29	2.59	3.03	2.11	1.08	0	0.1	up	yes
MSTRG.27146	RP11-111F5.2	MSTRG.27146.1	NA	NA	NA	NA	NA	0.19	0.01	0.37	1.83	1.49	1.02	0.47	-1.09	0.03	0.28	down	yes
MSTRG.27200	.	MSTRG.27200.1	NA	NA	NA	NA	NA	0.04	0	0.09	1.61	1.65	0.67	0.42	-1.25	0.02	0.27	down	yes
MSTRG.27227	APBA1	ENST00000265381;MSTRG.27227.2;MSTRG.27227.3	NA	NA	NA	NA	NA	1.05	1	1.06	3.74	3.73	3.88	0.43	-1.21	0	0.08	down	yes
MSTRG.2724	RP5-862P8.3	ENST00000258229;ENST00000496675;ENST00000344698;ENST00000462233;MSTRG.2724.3;ENST00000497623;ENST00000522067;ENST00000429988;MSTRG.2724.11;MSTRG.2724.10;ENST00000475463;MSTRG.2724.12;ENST00000484041;ENST00000490102;MSTRG.2724.17;ENST00000486012;ENST00000520463;ENST00000488780;ENST00000430153;ENST00000467336;ENST00000496510;ENST00000498302;ENST00000518351;ENST00000517808;ENST00000324142;ENST00000519530;ENST00000506013	NA	NA	NA	NA	NA	12.84	11.08	10.67	2.58	2.19	2.84	3.77	1.91	0	0.12	up	yes
MSTRG.27248	TMEM2	MSTRG.27248.1;ENST00000377044;ENST00000377057;ENST00000538669;ENST00000377066;ENST00000396272;ENST00000474495;ENST00000377055;ENST00000377043;ENST00000537329;ENST00000546219;ENST00000543165	GO:0007275(multicellular organismal development);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	NA	NA	NA	transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:11869]	4.02	4.89	9.58	22.62	19.04	20.8	0.28	-1.84	0.03	0.28	down	yes
MSTRG.27279	TLE1	ENST00000376499;MSTRG.27279.2;MSTRG.27279.3;MSTRG.27279.4;ENST00000376472;ENST00000491534;ENST00000464999;ENST00000418319;ENST00000376463;MSTRG.27279.10	NA	NA	NA	NA	NA	16	13.14	12.87	4.6	4.59	7.75	2.74	1.46	0.01	0.22	up	yes
MSTRG.27292	RMI1	ENST00000445877;ENST00000325875;ENST00000615118	GO:0002021(response to dietary excess);GO:0002023(reduction of food intake in response to dietary excess);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0009749(response to glucose);GO:0035264(multicellular organism growth);GO:0042593(glucose homeostasis)	NA	NA	NA	RecQ mediated genome instability 1 [Source:HGNC Symbol;Acc:HGNC:25764]	0.02	0.43	0.34	1.74	1.62	0.4	0.44	-1.19	0.03	0.3	down	yes
MSTRG.27294	RP11-213G2.3	MSTRG.27294.1;MSTRG.27294.2;ENST00000431724	NA	NA	NA	NA	NA	2.39	2.07	1.97	0.7	0.43	0.42	2.05	1.04	0.01	0.19	up	yes
MSTRG.27295	AGTPBP1	MSTRG.27295.1;ENST00000376083;ENST00000337006;MSTRG.27295.4;ENST00000357081;MSTRG.27295.6;ENST00000628899;ENST00000489265;ENST00000376081;ENST00000491784	GO:0001754(eye photoreceptor cell differentiation);GO:0004181(metallocarboxypeptidase activity);GO:0005488(binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0007005(mitochondrion organization);GO:0007628(adult walking behavior);GO:0008270(zinc ion binding);GO:0015631(tubulin binding);GO:0021549(cerebellum development);GO:0021680(cerebellar Purkinje cell layer development);GO:0021702(cerebellar Purkinje cell differentiation);GO:0021772(olfactory bulb development);GO:0035609(C-terminal protein deglutamylation);GO:0035610(protein side chain deglutamylation);GO:0042133(neurotransmitter metabolic process);GO:0050905(neuromuscular process);GO:0060041(retina development in camera-type eye)	NA	NA	NA	ATP/GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17258]	8.58	9.16	7.59	3.64	2.63	1.38	2.29	1.2	0.04	0.31	up	yes
MSTRG.27303	GOLM1	MSTRG.27303.1;ENST00000388712;ENST00000388711;ENST00000464314;ENST00000257504;ENST00000470762;ENST00000472919;ENST00000486130;ENST00000466178	GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0005887(integral component of plasma membrane);GO:0006997(nucleus organization);GO:0019216(regulation of lipid metabolic process);GO:0070062(extracellular exosome)	NA	NA	NA	golgi membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:15451]	4.42	3.7	3.37	13.4	8.03	7.3	0.43	-1.23	0.04	0.32	down	yes
MSTRG.27346	C9orf89	MSTRG.27346.1;MSTRG.27346.2;MSTRG.27346.3;ENST00000375464;ENST00000466409;ENST00000495641;ENST00000466929;ENST00000468781;ENST00000490488;ENST00000498243;ENST00000475574;ENST00000488630	GO:0005634(nucleus);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0016021(integral component of membrane);GO:0031966(mitochondrial membrane);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050700(CARD domain binding)	NA	NA	NA	chromosome 9 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:28148]	11.08	7.36	6.38	3.62	3.94	6.8	2.09	1.07	0.03	0.29	up	yes
MSTRG.27358	.	MSTRG.27358.1	NA	NA	NA	NA	NA	0.04	0.17	0.2	1.96	2.83	1.17	0.35	-1.5	0.02	0.26	down	yes
MSTRG.27365	PTPDC1	ENST00000375360;MSTRG.27365.2;ENST00000620992;ENST00000288976;MSTRG.27365.5;MSTRG.27365.6;ENST00000467049	GO:0004725(protein tyrosine phosphatase activity);GO:0005654(nucleoplasm);GO:0006470(protein dephosphorylation);GO:0007224(smoothened signaling pathway);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0030030(cell projection organization);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0060271(cilium morphogenesis)	NA	NA	NA	protein tyrosine phosphatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30184]	3.73	4.4	4.87	0.96	0.85	0.87	2.63	1.4	0	0.13	up	yes
MSTRG.27381	C9orf3	ENST00000277198;ENST00000297979;ENST00000375315;ENST00000427193;ENST00000489318;ENST00000424143;ENST00000428313;MSTRG.27381.8;ENST00000488186;ENST00000473778;ENST00000462125;MSTRG.27381.12;MSTRG.27381.13;MSTRG.27381.14;ENST00000479161;ENST00000451893;ENST00000460573;ENST00000478603;MSTRG.27381.19;MSTRG.27381.20;ENST00000471978;ENST00000445181;ENST00000478473;ENST00000496567;ENST00000463372;ENST00000482056;MSTRG.27381.27;MSTRG.27381.28;ENST00000489562	GO:0004177(aminopeptidase activity);GO:0005488(binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008270(zinc ion binding);GO:0019370(leukotriene biosynthetic process)	NA	NA	NA	chromosome 9 open reading frame 3 [Source:HGNC Symbol;Acc:HGNC:1361]	0.38	0.23	0.54	2.55	2.78	1.48	0.41	-1.3	0.02	0.27	down	yes
MSTRG.27390	PTCH1	ENST00000331920;ENST00000418258;ENST00000421141;ENST00000437951;ENST00000546744;ENST00000375290;ENST00000430669;MSTRG.27390.8;ENST00000429896;MSTRG.27390.10;MSTRG.27390.11;ENST00000547615;ENST00000549678;ENST00000488809;ENST00000548420;ENST00000553011;ENST00000547672;ENST00000548379;ENST00000548945;ENST00000553256;ENST00000550136;ENST00000468211;ENST00000551630;ENST00000551623;ENST00000551425	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001709(cell fate determination);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0005113(patched binding);GO:0005119(smoothened binding);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0007165(signal transduction);GO:0007224(smoothened signaling pathway);GO:0007346(regulation of mitotic cell cycle);GO:0007389(pattern specification process);GO:0007420(brain development);GO:0008158(hedgehog receptor activity);GO:0008201(heparin binding);GO:0008285(negative regulation of cell proliferation);GO:0008544(epidermis development);GO:0008589(regulation of smoothened signaling pathway);GO:0009612(response to mechanical stimulus);GO:0009887(organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0009957(epidermal cell fate specification);GO:0010157(response to chlorate);GO:0010875(positive regulation of cholesterol efflux);GO:0014069(postsynaptic density);GO:0014070(response to organic cyclic compound);GO:0015485(cholesterol binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016485(protein processing);GO:0021522(spinal cord motor neuron differentiation);GO:0021532(neural tube patterning);GO:0021904(dorsal/ventral neural tube patterning);GO:0021997(neural plate axis specification);GO:0030326(embryonic limb morphogenesis);GO:0030332(cyclin binding);GO:0030496(midbody);GO:0030666(endocytic vesicle membrane);GO:0030879(mammary gland development);GO:0032355(response to estradiol);GO:0032403(protein complex binding);GO:0032526(response to retinoic acid);GO:0032880(regulation of protein localization);GO:0035108(limb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0040015(negative regulation of multicellular organism growth);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043616(keratinocyte proliferation);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048471(perinuclear region of cytoplasm);GO:0048568(embryonic organ development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051782(negative regulation of cell division);GO:0060037(pharyngeal system development);GO:0060170(ciliary membrane);GO:0060603(mammary gland duct morphogenesis);GO:0060644(mammary gland epithelial cell differentiation);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061005(cell differentiation involved in kidney development);GO:0061053(somite development);GO:0071397(cellular response to cholesterol);GO:0072001(renal system development);GO:0072203(cell proliferation involved in metanephros development);GO:0072372(primary cilium);GO:0072661(protein targeting to plasma membrane);GO:0097108(hedgehog family protein binding)"	04340(Hedgehog signaling pathway);05200(Pathways in cancer);05217(Basal cell carcinoma)	NA	NA	patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]	1.21	1.16	0.82	6.57	4.49	6.19	0.3	-1.72	0.01	0.19	down	yes
MSTRG.27403	HSD17B3	ENST00000467499;ENST00000494814;ENST00000464104;ENST00000375263;ENST00000375262;ENST00000484816;ENST00000463517	GO:0005789(endoplasmic reticulum membrane);GO:0006702(androgen biosynthetic process);GO:0008152(metabolic process);GO:0008202(steroid metabolic process);GO:0016491(oxidoreductase activity);GO:0030539(male genitalia development);GO:0043231(intracellular membrane-bounded organelle);GO:0044281(small molecule metabolic process);GO:0047045(testosterone 17-beta-dehydrogenase (NADP+) activity);GO:0055114(oxidation-reduction process);GO:0061370(testosterone biosynthetic process)	00140(Steroid hormone biosynthesis);01100(Metabolic pathways)	NA	NA	hydroxysteroid (17-beta) dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212]	0.66	0.33	0.94	5.34	5.47	6.54	0.27	-1.9	0	0.17	down	yes
MSTRG.27409	SLC35D2	MSTRG.27409.1;MSTRG.27409.2;MSTRG.27409.3;MSTRG.27409.4;ENST00000490599;MSTRG.27409.5;ENST00000253270;ENST00000375259;MSTRG.27409.9;MSTRG.27409.10;ENST00000375257;ENST00000482643	GO:0000139(Golgi membrane);GO:0005338(nucleotide-sugar transmembrane transporter activity);GO:0005575(cellular_component);GO:0005975(carbohydrate metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0008150(biological_process);GO:0008643(carbohydrate transport);GO:0015165(pyrimidine nucleotide-sugar transmembrane transporter activity);GO:0015297(antiporter activity);GO:0016021(integral component of membrane);GO:0018146(keratan sulfate biosynthetic process);GO:0030203(glycosaminoglycan metabolic process);GO:0042339(keratan sulfate metabolic process);GO:0044281(small molecule metabolic process);GO:0055085(transmembrane transport);GO:0090481(pyrimidine nucleotide-sugar transmembrane transport);GO:0098656(anion transmembrane transport)	NA	NA	NA	"solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 [Source:HGNC Symbol;Acc:HGNC:20799]"	12.38	11.93	13.69	5.15	4.8	5.7	2.25	1.17	0	0.15	up	yes
MSTRG.2743	LYST	ENST00000389793;ENST00000473037;ENST00000389794;ENST00000462376;ENST00000475277;ENST00000461526;ENST00000487530;ENST00000489585;ENST00000492844;ENST00000465349;MSTRG.2743.11;MSTRG.2743.12;ENST00000468107;MSTRG.2743.13;MSTRG.2743.15;ENST00000468626;MSTRG.2743.19;MSTRG.2743.18;MSTRG.2743.17	NA	NA	NA	NA	NA	10.56	8.67	5.16	2.19	1.05	1.28	3.52	1.81	0.03	0.29	up	yes
MSTRG.27452	COL15A1	MSTRG.27452.2;ENST00000471477;ENST00000375001;ENST00000610452;ENST00000496686	GO:0001525(angiogenesis);GO:0005198(structural molecule activity);GO:0005201(extracellular matrix structural constituent);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005582(collagen type XV trimer);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0016021(integral component of membrane);GO:0022617(extracellular matrix disassembly);GO:0030154(cell differentiation);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0070062(extracellular exosome)	04974(Protein digestion and absorption)	NA	NA	"collagen, type XV, alpha 1 [Source:HGNC Symbol;Acc:HGNC:2192]"	6.26	7.17	7.48	0.41	0.29	1.69	5.25	2.39	0.02	0.25	up	yes
MSTRG.27503	KLF4	ENST00000497048;ENST00000493306;ENST00000374672;MSTRG.27503.1;ENST00000411706;ENST00000420475	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001010(sequence-specific DNA binding transcription factor recruiting transcription factor activity);GO:0001047(core promoter binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001085(RNA polymerase II transcription factor binding);GO:0001190(RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription);GO:0001221(transcription cofactor binding);GO:0003676(nucleic acid binding);GO:0003690(double-stranded DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005719(nuclear euchromatin);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0007500(mesodermal cell fate determination);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell proliferation);GO:0009913(epidermal cell differentiation);GO:0010033(response to organic substance);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0014740(negative regulation of muscle hyperplasia);GO:0019827(stem cell maintenance);GO:0030154(cell differentiation);GO:0030336(negative regulation of cell migration);GO:0031077(post-embryonic camera-type eye development);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032526(response to retinoic acid);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0035014(phosphatidylinositol 3-kinase regulator activity);GO:0035019(somatic stem cell maintenance);GO:0035166(post-embryonic hemopoiesis);GO:0042127(regulation of cell proliferation);GO:0042826(histone deacetylase binding);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043551(regulation of phosphatidylinositol 3-kinase activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044798(nuclear transcription factor complex);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045444(fat cell differentiation);GO:0045595(regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0046985(positive regulation of hemoglobin biosynthetic process);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0048730(epidermis morphogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051247(positive regulation of protein metabolic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0051973(positive regulation of telomerase activity);GO:0060070(canonical Wnt signaling pathway);GO:0060761(negative regulation of response to cytokine stimulus);GO:0070301(cellular response to hydrogen peroxide);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071300(cellular response to retinoic acid);GO:0071363(cellular response to growth factor stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071409(cellular response to cycloheximide);GO:0071499(cellular response to laminar fluid shear stress);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:1901653(cellular response to peptide);GO:2000342(negative regulation of chemokine (C-X-C motif) ligand 2 production)"	NA	NA	NA	Kruppel-like factor 4 (gut) [Source:HGNC Symbol;Acc:HGNC:6348]	14.18	8.56	10.96	1.97	2.35	1.29	4.74	2.25	0.01	0.2	up	yes
MSTRG.27546	FAM225B	ENST00000439875;ENST00000423546	NA	NA	NA	NA	NA	0.68	0.44	0.62	3.4	2.78	1.51	0.42	-1.26	0.03	0.3	down	yes
MSTRG.27547	FAM225A	ENST00000453010;ENST00000434051	NA	NA	NA	NA	NA	0.84	1	1.01	4.31	4.52	2.74	0.36	-1.46	0.01	0.2	down	yes
MSTRG.27550	SLC31A1	ENST00000374212;ENST00000496650	GO:0005375(copper ion transmembrane transporter activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005770(late endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006825(copper ion transport);GO:0006855(drug transmembrane transport);GO:0006878(cellular copper ion homeostasis);GO:0015088(copper uptake transmembrane transporter activity);GO:0015677(copper ion import);GO:0016021(integral component of membrane);GO:0035434(copper ion transmembrane transport);GO:0043025(neuronal cell body);GO:0055037(recycling endosome);GO:0055085(transmembrane transport);GO:0072719(cellular response to cisplatin);GO:1902861(copper ion import into cell)	04978(Mineral absorption)	NA	NA	"solute carrier family 31 (copper transporter), member 1 [Source:HGNC Symbol;Acc:HGNC:11016]"	7.84	9.38	6.98	2.13	2.61	1.6	2.68	1.42	0.01	0.21	up	yes
MSTRG.27557	RGS3	ENST00000374140;ENST00000350696;ENST00000317613;ENST00000466735;ENST00000343817;ENST00000464306;ENST00000374136;ENST00000462143;ENST00000492676;MSTRG.27557.19;MSTRG.27557.20;MSTRG.27557.21;MSTRG.27557.23;MSTRG.27557.24;MSTRG.27557.25;MSTRG.27557.22;MSTRG.27557.26;ENST00000489082;ENST00000488620;ENST00000485822;ENST00000487344;ENST00000467805;ENST00000462403;ENST00000613049;ENST00000620489;ENST00000497435;ENST00000490241	GO:0000188(inactivation of MAPK activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0038032(termination of G-protein coupled receptor signaling pathway);GO:0043547(positive regulation of GTPase activity)	04360(Axon guidance)	NA	NA	regulator of G-protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999]	8.13	7.57	5.79	1.33	1.3	1.32	3.66	1.87	0	0.16	up	yes
MSTRG.27563	RP11-9M16.2	MSTRG.27563.2;MSTRG.27563.1;MSTRG.27563.3;MSTRG.27563.4;MSTRG.27563.5;ENST00000307564;MSTRG.27563.6;ENST00000374079;ENST00000492875;ENST00000223791;ENST00000374075;ENST00000491133;ENST00000312033;ENST00000448674	NA	NA	NA	NA	NA	4.55	5.05	6.48	0.37	0.32	0.47	4.49	2.17	0	0.15	up	yes
MSTRG.27564	DFNB31	ENST00000374059;ENST00000362057;MSTRG.27564.2;ENST00000374057;ENST00000480518	GO:0001895(retina homeostasis);GO:0001917(photoreceptor inner segment);GO:0002141(stereocilia ankle link);GO:0002142(stereocilia ankle link complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005884(actin filament);GO:0005929(cilium);GO:0007605(sensory perception of sound);GO:0010628(positive regulation of gene expression);GO:0021694(cerebellar Purkinje cell layer formation);GO:0030426(growth cone);GO:0032391(photoreceptor connecting cilium);GO:0032420(stereocilium);GO:0032421(stereocilium bundle);GO:0032426(stereocilium bundle tip);GO:0036064(ciliary basal body);GO:0042803(protein homodimerization activity);GO:0045184(establishment of protein localization);GO:0046982(protein heterodimerization activity);GO:0050953(sensory perception of light stimulus);GO:0060122(inner ear receptor stereocilium organization);GO:1990075(periciliary membrane compartment);GO:1990227(paranodal junction maintenance);GO:1990696(USH2 complex)	NA	NA	NA	"deafness, autosomal recessive 31 [Source:HGNC Symbol;Acc:HGNC:16361]"	4.09	3.89	2.93	1.05	0.89	1.89	2.28	1.19	0.03	0.28	up	yes
MSTRG.27566	C9orf91	MSTRG.27566.1;ENST00000374050;ENST00000473413;ENST00000288502;ENST00000374049;ENST00000471206;MSTRG.27566.7;ENST00000482552	GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016021(integral component of membrane)	NA	NA	NA	chromosome 9 open reading frame 91 [Source:HGNC Symbol;Acc:HGNC:24513]	21.32	13.33	12.38	6.19	5.09	5.77	2.8	1.49	0.01	0.24	up	yes
MSTRG.27589	RP11-27I1.4	MSTRG.27589.1	NA	NA	NA	NA	NA	0.04	0.36	0.8	1.84	2.52	1.74	0.41	-1.29	0.03	0.29	down	yes
MSTRG.27590	PSMD5	ENST00000373920;ENST00000210313;MSTRG.27590.3;ENST00000373904;ENST00000373903;ENST00000496688;ENST00000476949;ENST00000471789	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000209(protein polyubiquitination);GO:0000278(mitotic cell cycle);GO:0000502(proteasome complex);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005488(binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006915(apoptotic process);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0010467(gene expression);GO:0012501(programmed cell death);GO:0016032(viral process);GO:0022624(proteasome accessory complex);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0034641(cellular nitrogen compound metabolic process);GO:0042590(antigen processing and presentation of exogenous peptide antigen via MHC class I);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043248(proteasome assembly);GO:0044281(small molecule metabolic process);GO:0045087(innate immune response);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070682(proteasome regulatory particle assembly);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway)"	NA	NA	NA	"proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 [Source:HGNC Symbol;Acc:HGNC:9563]"	4.16	5.38	6.17	12.6	11.46	9.4	0.44	-1.18	0	0.19	down	yes
MSTRG.27592	PHF19	ENST00000419155;ENST00000616568;ENST00000373896;ENST00000487555;ENST00000462229;ENST00000464712;ENST00000467266;ENST00000453868;ENST00000474402;ENST00000439674;ENST00000436309;ENST00000312189;ENST00000456291	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0010467(gene expression);GO:0016568(chromatin modification);GO:0019827(stem cell maintenance);GO:0035064(methylated histone binding);GO:0035098(ESC/E(Z) complex);GO:0040029(regulation of gene expression, epigenetic);GO:0045814(negative regulation of gene expression, epigenetic);GO:0048863(stem cell differentiation);GO:0061087(positive regulation of histone H3-K27 methylation)"	NA	NA	NA	PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566]	4.2	3.58	2.82	28.07	17.93	10.04	0.2	-2.3	0.02	0.28	down	yes
MSTRG.27637	LHX2	ENST00000373615;ENST00000488674	"GO:0001076(RNA polymerase II transcription factor binding transcription factor activity);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007498(mesoderm development);GO:0008270(zinc ion binding);GO:0009953(dorsal/ventral pattern formation);GO:0021537(telencephalon development);GO:0021772(olfactory bulb development);GO:0021978(telencephalon regionalization);GO:0021987(cerebral cortex development);GO:0022008(neurogenesis);GO:0030182(neuron differentiation);GO:0043565(sequence-specific DNA binding);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048675(axon extension);GO:0060041(retina development in camera-type eye);GO:2000678(negative regulation of transcription regulatory region DNA binding)"	NA	NA	NA	LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:6594]	0.58	0.72	0.25	2.43	2.74	2.39	0.42	-1.26	0.01	0.22	down	yes
MSTRG.2765	ACTN2	ENST00000542672;ENST00000546208;MSTRG.2765.4;ENST00000492634;ENST00000492101;ENST00000461367	"GO:0002576(platelet degranulation);GO:0005178(integrin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006936(muscle contraction);GO:0007155(cell adhesion);GO:0007268(synaptic transmission);GO:0007596(blood coagulation);GO:0008092(cytoskeletal protein binding);GO:0008307(structural constituent of muscle);GO:0019904(protein domain specific binding);GO:0030017(sarcomere);GO:0030018(Z disc);GO:0030035(microspike assembly);GO:0030049(muscle filament sliding);GO:0030168(platelet activation);GO:0030175(filopodium);GO:0030274(LIM domain binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0030375(thyroid hormone receptor coactivator activity);GO:0030864(cortical actin cytoskeleton);GO:0031093(platelet alpha granule lumen);GO:0031143(pseudopodium);GO:0031432(titin binding);GO:0042391(regulation of membrane potential);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0042981(regulation of apoptotic process);GO:0043197(dendritic spine);GO:0043267(negative regulation of potassium ion transport);GO:0043268(positive regulation of potassium ion transport);GO:0044325(ion channel binding);GO:0045214(sarcomere organization);GO:0046983(protein dimerization activity);GO:0048041(focal adhesion assembly);GO:0051015(actin filament binding);GO:0051289(protein homotetramerization);GO:0051373(FATZ binding);GO:0051695(actin filament uncapping);GO:0055013(cardiac muscle cell development);GO:0070062(extracellular exosome);GO:0070080(titin Z domain binding);GO:0086097(phospholipase C-activating angiotensin-activated signaling pathway);GO:0090002(establishment of protein localization to plasma membrane);GO:1901017(negative regulation of potassium ion transmembrane transporter activity);GO:1901018(positive regulation of potassium ion transmembrane transporter activity);GO:1903506(regulation of nucleic acid-templated transcription);GO:2000009(negative regulation of protein localization to cell surface);GO:2000273(positive regulation of receptor activity);GO:2001137(positive regulation of endocytic recycling);GO:2001259(positive regulation of cation channel activity)"	04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04670(Leukocyte transendothelial migration);04810(Regulation of actin cytoskeleton);05146(Amoebiasis);05322(Systemic lupus erythematosus);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))	NA	NA	"actinin, alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]"	2.47	2.59	3.44	0.32	0.32	0.47	2.8	1.49	0	0.17	up	yes
MSTRG.27656	HSPA5	ENST00000324460	GO:0001948(glycoprotein binding);GO:0002576(platelet degranulation);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005789(endoplasmic reticulum membrane);GO:0005790(smooth endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006983(ER overload response);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0007596(blood coagulation);GO:0008180(COP9 signalosome);GO:0009986(cell surface);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0021589(cerebellum structural organization);GO:0021680(cerebellar Purkinje cell layer development);GO:0021762(substantia nigra development);GO:0030168(platelet activation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030335(positive regulation of cell migration);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0030496(midbody);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031398(positive regulation of protein ubiquitination);GO:0031625(ubiquitin protein ligase binding);GO:0034663(endoplasmic reticulum chaperone complex);GO:0034975(protein folding in endoplasmic reticulum);GO:0034976(response to endoplasmic reticulum stress);GO:0035437(maintenance of protein localization in endoplasmic reticulum);GO:0036498(IRE1-mediated unfolded protein response);GO:0036499(PERK-mediated unfolded protein response);GO:0036500(ATF6-mediated unfolded protein response);GO:0042149(cellular response to glucose starvation);GO:0042470(melanosome);GO:0043022(ribosome binding);GO:0043066(negative regulation of apoptotic process);GO:0043209(myelin sheath);GO:0044267(cellular protein metabolic process);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0051787(misfolded protein binding);GO:0060904(regulation of protein folding in endoplasmic reticulum);GO:0070062(extracellular exosome);GO:0071236(cellular response to antibiotic);GO:0071353(cellular response to interleukin-4);GO:0090074(negative regulation of protein homodimerization activity);GO:1901998(toxin transport);GO:1903891(regulation of ATF6-mediated unfolded protein response);GO:1903894(regulation of IRE1-mediated unfolded protein response);GO:1903897(regulation of PERK-mediated unfolded protein response);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)	03060(Protein export);04141(Protein processing in endoplasmic reticulum);04612(Antigen processing and presentation);05020(Prion diseases)	NA	NA	"heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Source:HGNC Symbol;Acc:HGNC:5238]"	2416.14	2576.94	1167.78	294.97	312.73	238.55	6.62	2.73	0.02	0.25	up	yes
MSTRG.27671	ZBTB34	ENST00000319119;MSTRG.27671.2;ENST00000373452	"GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	zinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGNC:31446]	6.12	5.95	3.98	2.11	1.61	1.76	2.19	1.13	0.02	0.27	up	yes
MSTRG.27677	RPL12	ENST00000361436;ENST00000497825;ENST00000536368;ENST00000497322;ENST00000483598	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome)"	03010(Ribosome)	NA	NA	ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302]	720.22	613.57	608.71	254.99	307.59	418.51	2.42	1.27	0.01	0.2	up	yes
MSTRG.27695	ST6GALNAC4	MSTRG.27695.1;MSTRG.27695.2;ENST00000335791;ENST00000495983;ENST00000474282;ENST00000361444;ENST00000483438;ENST00000479747	"GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0006486(protein glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006493(protein O-linked glycosylation);GO:0006664(glycolipid metabolic process);GO:0008373(sialyltransferase activity);GO:0016021(integral component of membrane);GO:0016266(O-glycan processing);GO:0018279(protein N-linked glycosylation via asparagine);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0047290((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity);GO:0097503(sialylation)"	00604(Glycosphingolipid biosynthesis - ganglio series);01100(Metabolic pathways)	NA	NA	"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:17846]"	6.22	4.49	4.61	1.9	1.59	3.86	2.26	1.17	0.04	0.31	up	yes
MSTRG.27698	FAM102A	MSTRG.27698.1;ENST00000373095;ENST00000465821;ENST00000373084;ENST00000300434;ENST00000479828;ENST00000493175;ENST00000494606	GO:0005515(protein binding)	NA	NA	NA	"family with sequence similarity 102, member A [Source:HGNC Symbol;Acc:HGNC:31419]"	15.88	5.46	4.08	1.7	3.4	2.54	3.68	1.88	0.04	0.32	up	yes
MSTRG.27700	SLC25A25	ENST00000373068;ENST00000373069;ENST00000373066;ENST00000432073;ENST00000373064;ENST00000472769;ENST00000445012;ENST00000466983	GO:0002021(response to dietary excess);GO:0005509(calcium ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0014823(response to activity);GO:0016021(integral component of membrane);GO:0032094(response to food);GO:0035264(multicellular organism growth);GO:0043010(camera-type eye development);GO:0043231(intracellular membrane-bounded organelle);GO:0045333(cellular respiration);GO:0046034(ATP metabolic process);GO:0055085(transmembrane transport);GO:0060612(adipose tissue development);GO:0070062(extracellular exosome);GO:0070588(calcium ion transmembrane transport)	NA	NA	NA	"solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 [Source:HGNC Symbol;Acc:HGNC:20663]"	12.44	9.85	9.36	2.21	3.41	2.87	3.47	1.8	0	0.15	up	yes
MSTRG.27708	LCN2	ENST00000373017;ENST00000470902;ENST00000277480;ENST00000487719;ENST00000372998;ENST00000488391;ENST00000494317	GO:0002020(protease binding);GO:0005215(transporter activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005623(cell);GO:0005829(cytosol);GO:0006810(transport);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0009615(response to virus);GO:0009617(response to bacterium);GO:0009635(response to herbicide);GO:0010046(response to mycotoxin);GO:0010628(positive regulation of gene expression);GO:0015891(siderophore transport);GO:0031346(positive regulation of cell projection organization);GO:0031667(response to nutrient levels);GO:0031669(cellular response to nutrient levels);GO:0036094(small molecule binding);GO:0042493(response to drug);GO:0042803(protein homodimerization activity);GO:0045087(innate immune response);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0070207(protein homotrimerization);GO:0070301(cellular response to hydrogen peroxide);GO:0071222(cellular response to lipopolysaccharide);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand)	NA	NA	NA	lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526]	114.44	176.06	1238.31	0.44	0.39	10.43	133.48	7.06	0.04	0.33	up	yes
MSTRG.27716	SLC27A4	ENST00000372870;ENST00000300456	GO:0000038(very long-chain fatty acid metabolic process);GO:0000166(nucleotide binding);GO:0001579(medium-chain fatty acid transport);GO:0001676(long-chain fatty acid metabolic process);GO:0003824(catalytic activity);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005902(microvillus);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006810(transport);GO:0007584(response to nutrient);GO:0008152(metabolic process);GO:0015245(fatty acid transporter activity);GO:0015908(fatty acid transport);GO:0015909(long-chain fatty acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031526(brush border membrane);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0042760(very long-chain fatty acid catabolic process);GO:0043588(skin development);GO:0044539(long-chain fatty acid import);GO:0055085(transmembrane transport)	03320(PPAR signaling pathway);04975(Fat digestion and absorption)	NA	NA	"solute carrier family 27 (fatty acid transporter), member 4 [Source:HGNC Symbol;Acc:HGNC:10998]"	4.55	4.2	4.89	13.44	11.52	8.11	0.43	-1.23	0.02	0.26	down	yes
MSTRG.27724	C9orf16	ENST00000372994;ENST00000492588;ENST00000489240;ENST00000486420	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process)	NA	NA	NA	chromosome 9 open reading frame 16 [Source:HGNC Symbol;Acc:HGNC:17823]	34.02	25.85	37.15	5.25	6.11	16.81	4.97	2.31	0.02	0.28	up	yes
MSTRG.27741	SPTAN1	ENST00000372731;ENST00000630804;ENST00000627441;ENST00000625282;ENST00000372739;MSTRG.27741.3;ENST00000358161;ENST00000497216;ENST00000630866;ENST00000472211;ENST00000627809;ENST00000475367;ENST00000628867;ENST00000461855;ENST00000631315;ENST00000631121;ENST00000629137;ENST00000629378;ENST00000476825;ENST00000491712;ENST00000629047;ENST00000629089;ENST00000628614;ENST00000625980;ENST00000630763;ENST00000630147;ENST00000630981	GO:0003779(actin binding);GO:0005200(structural constituent of cytoskeleton);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0005916(fascia adherens);GO:0006915(apoptotic process);GO:0006921(cellular component disassembly involved in execution phase of apoptosis);GO:0007411(axon guidance);GO:0008091(spectrin);GO:0012501(programmed cell death);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0016328(lateral plasma membrane);GO:0030018(Z disc);GO:0030507(spectrin binding);GO:0030863(cortical cytoskeleton);GO:0032437(cuticular plate);GO:0043231(intracellular membrane-bounded organelle);GO:0046982(protein heterodimerization activity);GO:0051693(actin filament capping);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)	04530(Tight junction)	NA	NA	"spectrin, alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]"	6.33	7.43	6.77	17.27	17.64	20.39	0.4	-1.32	0	0.16	down	yes
MSTRG.27744	WDR34	ENST00000372715;ENST00000483181;ENST00000480613;ENST00000473486;ENST00000451652;ENST00000419989	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005868(cytoplasmic dynein complex);GO:0005930(axoneme);GO:0006996(organelle organization);GO:0036064(ciliary basal body);GO:0072372(primary cilium);GO:0097542(ciliary tip)	NA	NA	NA	WD repeat domain 34 [Source:HGNC Symbol;Acc:HGNC:28296]	4.06	2.74	4.48	16.21	20.3	12.72	0.29	-1.79	0.01	0.24	down	yes
MSTRG.27756	NUP188	ENST00000372592;ENST00000412476;ENST00000482796;ENST00000372577;MSTRG.27756.18;ENST00000464729;MSTRG.27756.20;ENST00000465344;ENST00000477069;ENST00000491502;ENST00000467044;ENST00000485158;ENST00000495726;ENST00000487952	GO:0000278(mitotic cell cycle);GO:0005488(binding);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005975(carbohydrate metabolic process);GO:0007077(mitotic nuclear envelope disassembly);GO:0008645(hexose transport);GO:0010467(gene expression);GO:0010827(regulation of glucose transport);GO:0015031(protein transport);GO:0015758(glucose transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019221(cytokine-mediated signaling pathway);GO:0034605(cellular response to heat);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0051028(mRNA transport);GO:0055085(transmembrane transport);GO:1900034(regulation of cellular response to heat)	03013(RNA transport)	NA	NA	nucleoporin 188kDa [Source:HGNC Symbol;Acc:HGNC:17859]	5.82	5.75	6.2	13.86	13.52	8.43	0.49	-1.04	0.03	0.3	down	yes
MSTRG.27757	DOLK	ENST00000372586	GO:0004168(dolichol kinase activity);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0016310(phosphorylation);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043048(dolichyl monophosphate biosynthetic process);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process)	00510(N-Glycan biosynthesis);01100(Metabolic pathways)	K00902	2.7.1.108	dolichol kinase [Source:HGNC Symbol;Acc:HGNC:23406]	1.04	1.41	3.42	9.52	9.61	7.5	0.25	-2.01	0.02	0.28	down	yes
MSTRG.27787	ASS1	ENST00000352480;ENST00000372394;ENST00000372393;ENST00000422569;ENST00000443588;ENST00000467695;ENST00000493984	GO:0000050(urea cycle);GO:0000052(citrulline metabolic process);GO:0000053(argininosuccinate metabolic process);GO:0001822(kidney development);GO:0001889(liver development);GO:0004055(argininosuccinate synthase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0005764(lysosome);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006526(arginine biosynthetic process);GO:0006531(aspartate metabolic process);GO:0006953(acute-phase response);GO:0007494(midgut development);GO:0007568(aging);GO:0007584(response to nutrient);GO:0009636(response to toxic substance);GO:0010043(response to zinc ion);GO:0010046(response to mycotoxin);GO:0014075(response to amine);GO:0015643(toxic substance binding);GO:0016597(amino acid binding);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0034641(cellular nitrogen compound metabolic process);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043200(response to amino acid);GO:0043204(perikaryon);GO:0043434(response to peptide hormone);GO:0044281(small molecule metabolic process);GO:0044822(poly(A) RNA binding);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0060416(response to growth hormone);GO:0060539(diaphragm development);GO:0070062(extracellular exosome);GO:0070542(response to fatty acid);GO:0070852(cell body fiber);GO:0071222(cellular response to lipopolysaccharide);GO:0071230(cellular response to amino acid stimulus);GO:0071242(cellular response to ammonium ion);GO:0071320(cellular response to cAMP);GO:0071346(cellular response to interferon-gamma);GO:0071356(cellular response to tumor necrosis factor);GO:0071377(cellular response to glucagon stimulus);GO:0071400(cellular response to oleic acid);GO:0071418(cellular response to amine stimulus);GO:0071499(cellular response to laminar fluid shear stress);GO:0071549(cellular response to dexamethasone stimulus);GO:1903038(negative regulation of leukocyte cell-cell adhesion)	"00250(Alanine, aspartate and glutamate metabolism);00330(Arginine and proline metabolism);01100(Metabolic pathways)"	NA	NA	argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]	3.93	3.48	4.24	0.04	0.05	0.02	5.4	2.43	0	0.08	up	yes
MSTRG.27791	EXOSC2	ENST00000372358;ENST00000546165;ENST00000430138;ENST00000490641;ENST00000372352;ENST00000372351;ENST00000463488;ENST00000495699;ENST00000467138	"GO:0000175(3'-5'-exoribonuclease activity);GO:0000176(nuclear exosome (RNase complex));GO:0000177(cytoplasmic exosome (RNase complex));GO:0000178(exosome (RNase complex));GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000467(exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0008312(7S RNA binding);GO:0010467(gene expression);GO:0030307(positive regulation of cell growth);GO:0034427(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5');GO:0034475(U4 snRNA 3'-end processing);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0071034(CUT catabolic process);GO:0071035(nuclear polyadenylation-dependent rRNA catabolic process);GO:0071038(nuclear polyadenylation-dependent tRNA catabolic process);GO:0071049(nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription);GO:0071051(polyadenylation-dependent snoRNA 3'-end processing)"	03018(RNA degradation)	NA	NA	exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097]	3.3	4.41	5.13	10.22	11.6	11.47	0.41	-1.29	0.01	0.22	down	yes
MSTRG.27823	GTF3C5	ENST00000372099;ENST00000372097;MSTRG.27823.3;MSTRG.27823.4;ENST00000372108;ENST00000439697;ENST00000485692;ENST00000461871;ENST00000435745;ENST00000489842	"GO:0000127(transcription factor TFIIIC complex);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006383(transcription from RNA polymerase III promoter);GO:0010467(gene expression);GO:0035914(skeletal muscle cell differentiation);GO:0042791(5S class rRNA transcription from RNA polymerase III type 1 promoter);GO:0042797(tRNA transcription from RNA polymerase III promoter)"	NA	NA	NA	"general transcription factor IIIC, polypeptide 5, 63kDa [Source:HGNC Symbol;Acc:HGNC:4668]"	7.08	6.5	8	15.86	18.55	14.07	0.48	-1.06	0.01	0.23	down	yes
MSTRG.27826	SURF6	ENST00000372022;ENST00000468290	GO:0001652(granular component);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0044822(poly(A) RNA binding)	NA	NA	NA	surfeit 6 [Source:HGNC Symbol;Acc:HGNC:11478]	12.02	5.55	12.83	4.35	4.98	6	2.32	1.22	0.04	0.31	up	yes
MSTRG.27891	SNHG7	ENST00000414282;MSTRG.27891.2;ENST00000416970;ENST00000436596;ENST00000447221	NA	NA	NA	NA	NA	12.15	11.64	11.68	3.67	6.41	6.86	2.32	1.21	0.02	0.26	up	yes
MSTRG.27911	UAP1L1	MSTRG.27911.1;ENST00000409858;ENST00000476184;MSTRG.27911.4;ENST00000360271;ENST00000474787	GO:0008152(metabolic process);GO:0070569(uridylyltransferase activity)	00520(Amino sugar and nucleotide sugar metabolism);01100(Metabolic pathways)	NA	NA	UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]	8.63	3.56	7.33	2.28	1.74	2.01	2.96	1.57	0.03	0.28	up	yes
MSTRG.27917	ANAPC2	ENST00000487917;ENST00000323927;MSTRG.27917.3;ENST00000493730;ENST00000483432;ENST00000471131;ENST00000495611;ENST00000618649	GO:0000278(mitotic cell cycle);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007067(mitotic nuclear division);GO:0007094(mitotic spindle assembly checkpoint);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0031915(positive regulation of synaptic plasticity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0045773(positive regulation of axon extension);GO:0050775(positive regulation of dendrite morphogenesis);GO:0051301(cell division);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0061630(ubiquitin protein ligase activity);GO:0070979(protein K11-linked ubiquitination);GO:0090129(positive regulation of synapse maturation)	04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis);04914(Progesterone-mediated oocyte maturation)	NA	NA	anaphase promoting complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19989]	1.43	1.59	2.31	6.3	6.05	4.93	0.38	-1.41	0.01	0.2	down	yes
MSTRG.2795	EXO1	ENST00000519225;MSTRG.2795.2;MSTRG.2795.3;MSTRG.2795.4;MSTRG.2795.5;MSTRG.2795.6;ENST00000366548;ENST00000423131;ENST00000523590;ENST00000348581;ENST00000518483;ENST00000437497;ENST00000450748;ENST00000493702;ENST00000469419;ENST00000521202;ENST00000518741	"GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0003677(DNA binding);GO:0003824(catalytic activity);GO:0004518(nuclease activity);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006298(mismatch repair);GO:0006310(DNA recombination);GO:0008409(5'-3' exonuclease activity);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0016788(hydrolase activity, acting on ester bonds);GO:0035312(5'-3' exodeoxyribonuclease activity);GO:0043566(structure-specific DNA binding);GO:0045145(single-stranded DNA 5'-3' exodeoxyribonuclease activity);GO:0045190(isotype switching);GO:0046872(metal ion binding);GO:0048256(flap endonuclease activity);GO:0051321(meiotic cell cycle);GO:0051908(double-stranded DNA 5'-3' exodeoxyribonuclease activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic)"	03430(Mismatch repair)	NA	NA	exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3511]	2.11	2.43	1.29	14.59	11.83	5.11	0.21	-2.24	0.03	0.28	down	yes
MSTRG.27954	MT-ND5	MSTRG.27954.2	NA	NA	NA	NA	NA	0	0.37	0.43	983.13	1200.06	1533.19	0	-9.93	0	0.08	down	yes
MSTRG.27969	AKAP17A	ENST00000313871;ENST00000474361;ENST00000381261	"GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006397(mRNA processing);GO:0007165(signal transduction);GO:0008380(RNA splicing);GO:0016607(nuclear speck);GO:0042113(B cell activation);GO:0043484(regulation of RNA splicing);GO:0044822(poly(A) RNA binding);GO:0051018(protein kinase A binding)"	NA	NA	NA	A kinase (PRKA) anchor protein 17A [Source:HGNC Symbol;Acc:HGNC:18783]	10.5	8.3	7.96	2.76	2.9	5.67	2.65	1.41	0.02	0.25	up	yes
MSTRG.27975	ARSE	MSTRG.27975.1;ENST00000545496;ENST00000540563;ENST00000381134;ENST00000438544;MSTRG.27975.6;ENST00000483425;ENST00000496095	GO:0001501(skeletal system development);GO:0003824(catalytic activity);GO:0004065(arylsulfatase activity);GO:0005788(endoplasmic reticulum lumen);GO:0005795(Golgi stack);GO:0006665(sphingolipid metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0008152(metabolic process);GO:0008484(sulfuric ester hydrolase activity);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0046872(metal ion binding);GO:0070062(extracellular exosome)	NA	NA	NA	arylsulfatase E (chondrodysplasia punctata 1) [Source:HGNC Symbol;Acc:HGNC:719]	1.26	1.52	1.67	4.29	4.22	5.03	0.44	-1.17	0	0.17	down	yes
MSTRG.27993	SHROOM2	ENST00000380913;MSTRG.27993.2;ENST00000493668;ENST00000418909;ENST00000452575	GO:0002089(lens morphogenesis in camera-type eye);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0005923(bicellular tight junction);GO:0005938(cell cortex);GO:0007420(brain development);GO:0008013(beta-catenin binding);GO:0008057(eye pigment granule organization);GO:0015280(ligand-gated sodium channel activity);GO:0016324(apical plasma membrane);GO:0016477(cell migration);GO:0019904(protein domain specific binding);GO:0030835(negative regulation of actin filament depolymerization);GO:0030864(cortical actin cytoskeleton);GO:0031941(filamentous actin);GO:0032401(establishment of melanosome localization);GO:0032438(melanosome organization);GO:0035725(sodium ion transmembrane transport);GO:0043010(camera-type eye development);GO:0043025(neuronal cell body);GO:0043296(apical junction complex);GO:0043482(cellular pigment accumulation);GO:0043583(ear development);GO:0045176(apical protein localization);GO:0045217(cell-cell junction maintenance);GO:0048593(camera-type eye morphogenesis);GO:0051015(actin filament binding);GO:0070062(extracellular exosome)	NA	NA	NA	shroom family member 2 [Source:HGNC Symbol;Acc:HGNC:630]	0.33	0.3	0.37	7.55	6.46	3.36	0.17	-2.52	0.01	0.2	down	yes
MSTRG.28015	ASB9	ENST00000380485;ENST00000380488;ENST00000546332;ENST00000473862;ENST00000470015	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0045732(positive regulation of protein catabolic process)	NA	NA	NA	ankyrin repeat and SOCS box containing 9 [Source:HGNC Symbol;Acc:HGNC:17184]	0.13	0.21	0.15	5.41	5.08	2.87	0.17	-2.54	0	0.17	down	yes
MSTRG.28024	ZRSR2	MSTRG.28024.1;ENST00000380308;ENST00000307771;MSTRG.28024.4	NA	NA	NA	NA	NA	12.01	13.21	11.58	4.25	3.89	2.39	2.62	1.39	0.01	0.21	up	yes
MSTRG.28091	RP11-298C3.2	ENST00000496795	NA	NA	NA	NA	NA	1.12	1.29	1.26	3.83	6.19	4.4	0.4	-1.34	0.01	0.24	down	yes
MSTRG.28122	SYTL5	MSTRG.28122.1;MSTRG.28122.2;ENST00000567273;ENST00000297875;ENST00000456733	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0016079(synaptic vesicle exocytosis);GO:0017137(Rab GTPase binding);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0048791(calcium ion-dependent exocytosis of neurotransmitter);GO:0070382(exocytic vesicle)	NA	NA	NA	synaptotagmin-like 5 [Source:HGNC Symbol;Acc:HGNC:15589]	0.4	0.43	0.43	2.12	4.04	2.29	0.39	-1.35	0.02	0.27	down	yes
MSTRG.28137	MID1IP1	ENST00000457894;ENST00000614558;ENST00000378474;ENST00000336949	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005874(microtubule);GO:0006629(lipid metabolic process);GO:0007026(negative regulation of microtubule depolymerization);GO:0008022(protein C-terminus binding);GO:0015630(microtubule cytoskeleton);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0046890(regulation of lipid biosynthetic process);GO:0051258(protein polymerization);GO:0051351(positive regulation of ligase activity)	NA	NA	NA	MID1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20715]	9.63	9.25	10.06	3.64	2.86	3	2.48	1.31	0	0.15	up	yes
MSTRG.28187	RBM10	ENST00000377604;MSTRG.28187.2;MSTRG.28187.3;ENST00000345781;ENST00000628161;ENST00000329236;ENST00000496012;ENST00000478410	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006397(mRNA processing);GO:0008150(biological_process);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell proliferation);GO:0008380(RNA splicing);GO:0032403(protein complex binding);GO:0034391(regulation of smooth muscle cell apoptotic process);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0042802(identical protein binding);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0070935(3'-UTR-mediated mRNA stabilization)"	NA	NA	NA	RNA binding motif protein 10 [Source:HGNC Symbol;Acc:HGNC:9896]	7.67	8.2	11.64	25.51	24.13	22.57	0.38	-1.41	0.01	0.22	down	yes
MSTRG.28221	SSX4	ENST00000620320;ENST00000595689	"GO:0003676(nucleic acid binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)"	NA	NA	NA	"synovial sarcoma, X breakpoint 4 [Source:HGNC Symbol;Acc:HGNC:11338]"	1.35	1.79	1.34	7.08	9.66	3.1	0.29	-1.79	0.04	0.33	down	yes
MSTRG.28222	SSX4B	ENST00000595235;MSTRG.28222.2;ENST00000619890	"GO:0003676(nucleic acid binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)"	NA	NA	NA	"synovial sarcoma, X breakpoint 4B [Source:HGNC Symbol;Acc:HGNC:16880]"	1.43	1.77	1.47	7.43	9.37	3.31	0.29	-1.77	0.04	0.31	down	yes
MSTRG.28229	RBM3	MSTRG.28229.1;ENST00000472897;ENST00000488216;ENST00000466764;ENST00000490127;ENST00000491240;ENST00000489344;ENST00000376759;ENST00000485213;ENST00000376755;MSTRG.28229.11;ENST00000491236;ENST00000354480	GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0006412(translation);GO:0006417(regulation of translation);GO:0009409(response to cold);GO:0015934(large ribosomal subunit);GO:0030425(dendrite);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0043023(ribosomal large subunit binding);GO:0044822(poly(A) RNA binding);GO:0045727(positive regulation of translation)	NA	NA	NA	"RNA binding motif (RNP1, RRM) protein 3 [Source:HGNC Symbol;Acc:HGNC:9900]"	10.09	9.81	15.63	30.41	31.77	22.31	0.41	-1.3	0.03	0.3	down	yes
MSTRG.28233	SUV39H1	ENST00000337852;ENST00000376687;MSTRG.28233.3;ENST00000482260;ENST00000462786	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000183(chromatin silencing at rDNA);GO:0000775(chromosome, centromeric region);GO:0000792(heterochromatin);GO:0000794(condensed nuclear chromosome);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001975(response to amphetamine);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005652(nuclear lamina);GO:0005654(nucleoplasm);GO:0005677(chromatin silencing complex);GO:0006325(chromatin organization);GO:0006351(transcription, DNA-templated);GO:0006364(rRNA processing);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0008270(zinc ion binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0010467(gene expression);GO:0016032(viral process);GO:0018024(histone-lysine N-methyltransferase activity);GO:0030154(cell differentiation);GO:0031667(response to nutrient levels);GO:0033553(rDNA heterochromatin);GO:0034968(histone lysine methylation);GO:0036123(histone H3-K9 dimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0040029(regulation of gene expression, epigenetic);GO:0042054(histone methyltransferase activity);GO:0042754(negative regulation of circadian rhythm);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0047485(protein N-terminus binding);GO:0048511(rhythmic process);GO:0051567(histone H3-K9 methylation);GO:0071456(cellular response to hypoxia)"	00310(Lysine degradation)	NA	NA	suppressor of variegation 3-9 homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:11479]	1.35	1.92	1.35	10.1	10.28	5.66	0.22	-2.17	0	0.19	down	yes
MSTRG.28239	SLC35A2	ENST00000247138;ENST00000376529;ENST00000376521;ENST00000413561;ENST00000452555;ENST00000616181;ENST00000445167;ENST00000376515;ENST00000446885;ENST00000376512	GO:0000139(Golgi membrane);GO:0005338(nucleotide-sugar transmembrane transporter activity);GO:0005351(sugar:proton symporter activity);GO:0005459(UDP-galactose transmembrane transporter activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006012(galactose metabolic process);GO:0006810(transport);GO:0008643(carbohydrate transport);GO:0015780(nucleotide-sugar transport);GO:0015785(UDP-galactose transport);GO:0015992(proton transport);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0072334(UDP-galactose transmembrane transport);GO:1901679(nucleotide transmembrane transport)	NA	NA	NA	"solute carrier family 35 (UDP-galactose transporter), member A2 [Source:HGNC Symbol;Acc:HGNC:11022]"	14.83	14.87	10.47	3.21	4.16	6.09	3.06	1.61	0.02	0.25	up	yes
MSTRG.28240	PIM2	ENST00000376509;ENST00000485431;ENST00000442430	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0006468(protein phosphorylation);GO:0007140(male meiosis);GO:0007346(regulation of mitotic cell cycle);GO:0008283(cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0008637(apoptotic mitochondrial changes);GO:0009615(response to virus);GO:0010508(positive regulation of autophagy);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046777(protein autophosphorylation);GO:0050821(protein stabilization)"	05221(Acute myeloid leukemia)	NA	NA	"Pim-2 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8987]"	16.47	11.57	9.21	4.17	5.51	7.59	2.56	1.36	0.02	0.25	up	yes
MSTRG.28281	MAGED1	ENST00000375772;ENST00000375722;ENST00000326587;ENST00000375695;ENST00000470461;ENST00000494718;ENST00000485420;ENST00000482188;ENST00000482599;ENST00000473931	"GO:0000785(chromatin);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0012501(programmed cell death);GO:0032922(circadian regulation of gene expression);GO:0042752(regulation of circadian rhythm);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043234(protein complex);GO:0043406(positive regulation of MAP kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050680(negative regulation of epithelial cell proliferation);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:2001235(positive regulation of apoptotic signaling pathway)"	04722(Neurotrophin signaling pathway)	NA	NA	melanoma antigen family D1 [Source:HGNC Symbol;Acc:HGNC:6813]	15.48	15.01	18.95	37.77	32.42	46.72	0.46	-1.12	0.02	0.27	down	yes
MSTRG.28314	SMC1A	ENST00000322213;ENST00000375340;ENST00000469129;ENST00000463684	"GO:0000070(mitotic sister chromatid segregation);GO:0000278(mitotic cell cycle);GO:0000398(mRNA splicing, via spliceosome);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000794(condensed nuclear chromosome);GO:0003682(chromatin binding);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0007064(mitotic sister chromatid cohesion);GO:0007093(mitotic cell cycle checkpoint);GO:0007126(meiotic nuclear division);GO:0008280(cohesin core heterodimer);GO:0008380(RNA splicing);GO:0009314(response to radiation);GO:0010467(gene expression);GO:0016925(protein sumoylation);GO:0019827(stem cell maintenance);GO:0030893(meiotic cohesin complex);GO:0032876(negative regulation of DNA endoreduplication);GO:0036033(mediator complex binding);GO:0042770(signal transduction in response to DNA damage);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0046982(protein heterodimerization activity);GO:0051276(chromosome organization);GO:0051301(cell division)"	04110(Cell cycle);04114(Oocyte meiosis)	NA	NA	structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]	5.17	6.61	7.18	32.74	29.81	13.55	0.22	-2.17	0.02	0.25	down	yes
MSTRG.28350	FOXR2	MSTRG.28350.1;MSTRG.28350.2	NA	NA	NA	NA	NA	0.37	0.42	0.9	2.57	1.9	1.49	0.46	-1.11	0.02	0.27	down	yes
MSTRG.28363	ZXDB	ENST00000374888	"GO:0003674(molecular_function);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008150(biological_process);GO:0046872(metal ion binding)"	NA	NA	NA	"zinc finger, X-linked, duplicated B [Source:HGNC Symbol;Acc:HGNC:13199]"	3.52	3.92	3.59	0	1.34	0.78	3.37	1.75	0.04	0.3	up	yes
MSTRG.28373	LAS1L	ENST00000374807;ENST00000374811;ENST00000374804;ENST00000484069;ENST00000469091	GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0006364(rRNA processing);GO:0016020(membrane);GO:0044822(poly(A) RNA binding);GO:0071339(MLL1 complex)	NA	NA	NA	LAS1-like (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:25726]	5.05	5.48	8.07	13.91	15.27	12.5	0.45	-1.15	0.02	0.28	down	yes
MSTRG.28376	OPHN1	ENST00000355520;MSTRG.28376.2;ENST00000484842;ENST00000467444;ENST00000491714	"GO:0003779(actin binding);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005543(phospholipid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006930(substrate-dependent cell migration, cell extension);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0015629(actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0030100(regulation of endocytosis);GO:0030425(dendrite);GO:0035255(ionotropic glutamate receptor binding);GO:0043195(terminal bouton);GO:0043197(dendritic spine);GO:0043547(positive regulation of GTPase activity);GO:0048488(synaptic vesicle endocytosis);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:1901799(negative regulation of proteasomal protein catabolic process)"	NA	NA	NA	oligophrenin 1 [Source:HGNC Symbol;Acc:HGNC:8148]	2.06	2.93	2.46	5.79	6.14	9.53	0.44	-1.18	0.04	0.31	down	yes
MSTRG.28392	KIF4A	MSTRG.28392.1;MSTRG.28392.2;ENST00000374403	GO:0000281(mitotic cytokinesis);GO:0003677(DNA binding);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005876(spindle microtubule);GO:0006996(organelle organization);GO:0007018(microtubule-based movement);GO:0007411(axon guidance);GO:0007596(blood coagulation);GO:0008017(microtubule binding);GO:0008089(anterograde axon cargo transport);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030496(midbody);GO:0051256(mitotic spindle midzone assembly)	NA	NA	NA	kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339]	1.98	1.97	0.85	38.31	39.94	10.03	0.07	-3.76	0.02	0.27	down	yes
MSTRG.28413	OGT	ENST00000373719;MSTRG.28413.2;MSTRG.28413.3;MSTRG.28413.4;ENST00000488174;ENST00000373701;ENST00000472270;ENST00000498566;ENST00000444774;ENST00000455587;ENST00000459760;ENST00000462638;ENST00000466181;ENST00000474633	"GO:0000123(histone acetyltransferase complex);GO:0005515(protein binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006110(regulation of glycolytic process);GO:0006325(chromatin organization);GO:0006493(protein O-linked glycosylation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007584(response to nutrient);GO:0008047(enzyme activator activity);GO:0008375(acetylglucosaminyltransferase activity);GO:0016262(protein N-acetylglucosaminyltransferase activity);GO:0030854(positive regulation of granulocyte differentiation);GO:0031397(negative regulation of protein ubiquitination);GO:0032868(response to insulin);GO:0032922(circadian regulation of gene expression);GO:0035020(regulation of Rac protein signal transduction);GO:0043085(positive regulation of catalytic activity);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0045862(positive regulation of proteolysis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046626(regulation of insulin receptor signaling pathway);GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0048015(phosphatidylinositol-mediated signaling);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0061087(positive regulation of histone H3-K27 methylation);GO:0070688(MLL5-L complex);GO:0071300(cellular response to retinoic acid);GO:0080182(histone H3-K4 trimethylation);GO:0090526(regulation of gluconeogenesis involved in cellular glucose homeostasis);GO:0097363(protein O-GlcNAc transferase activity)"	00514(Other types of O-glycan biosynthesis)	NA	NA	O-linked N-acetylglucosamine (GlcNAc) transferase [Source:HGNC Symbol;Acc:HGNC:8127]	21.15	20.67	26.07	10.86	8.8	11.73	2.08	1.05	0.02	0.25	up	yes
MSTRG.28481	HK2P1	MSTRG.28481.1	NA	NA	NA	NA	NA	6.5	10.04	8	1.17	1.96	3.1	3.15	1.66	0.03	0.3	up	yes
MSTRG.28514	CSTF2	ENST00000415585;ENST00000372972;ENST00000475126;ENST00000413437	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006378(mRNA polyadenylation);GO:0006379(mRNA cleavage);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0031124(mRNA 3'-end processing);GO:0044822(poly(A) RNA binding);GO:0071920(cleavage body)"	03015(mRNA surveillance pathway)	NA	NA	"cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa [Source:HGNC Symbol;Acc:HGNC:2484]"	6.01	8.07	12.09	32.41	34.87	18.86	0.26	-1.94	0.02	0.27	down	yes
MSTRG.28523	CENPI	MSTRG.28523.1	NA	NA	NA	NA	NA	0	0.03	0.1	4.84	4.92	1.24	0.19	-2.37	0.03	0.28	down	yes
MSTRG.28530	ARMCX1	MSTRG.28530.1;MSTRG.28530.2;ENST00000372829	GO:0005488(binding);GO:0005515(protein binding);GO:0016021(integral component of membrane)	NA	NA	NA	"armadillo repeat containing, X-linked 1 [Source:HGNC Symbol;Acc:HGNC:18073]"	16.35	17.32	13.93	7.24	7.08	7.01	2.03	1.02	0	0.18	up	yes
MSTRG.28544	BEX4	ENST00000372695;ENST00000372691	GO:0005634(nucleus);GO:0005737(cytoplasm)	NA	NA	NA	"brain expressed, X-linked 4 [Source:HGNC Symbol;Acc:HGNC:25475]"	7.96	11.3	15.55	0.73	0.66	1.46	6.08	2.6	0.01	0.23	up	yes
MSTRG.28547	BEX2	ENST00000372677;ENST00000536889;ENST00000372674;ENST00000449185	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0042981(regulation of apoptotic process);GO:0051726(regulation of cell cycle)	NA	NA	NA	brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933]	52.85	55.71	71.84	1.83	1.7	3.84	20	4.32	0	0.15	up	yes
MSTRG.28557	RAB9B	ENST00000243298	"GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005764(lysosome);GO:0005770(late endosome);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0015031(protein transport);GO:0016020(membrane);GO:0019003(GDP binding);GO:0030670(phagocytic vesicle membrane);GO:0032482(Rab protein signal transduction);GO:0042147(retrograde transport, endosome to Golgi);GO:0045335(phagocytic vesicle)"	05162(Measles)	NA	NA	"RAB9B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14090]"	0.16	0.24	0.62	1.91	1.42	0.95	0.48	-1.06	0.03	0.28	down	yes
MSTRG.28566	PLP1	ENST00000434483;ENST00000494475;ENST00000455268;ENST00000422393;ENST00000433491;ENST00000612423;ENST00000443502;MSTRG.28566.8;MSTRG.28566.9;ENST00000619236;ENST00000621218;ENST00000619257;ENST00000465975;ENST00000480325;ENST00000485931;ENST00000495678;ENST00000479569;ENST00000478642;ENST00000461231;ENST00000466486;ENST00000494119;ENST00000496836	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0007229(integrin-mediated signaling pathway);GO:0007268(synaptic transmission);GO:0008366(axon ensheathment);GO:0010001(glial cell differentiation);GO:0010628(positive regulation of gene expression);GO:0014002(astrocyte development);GO:0016021(integral component of membrane);GO:0019911(structural constituent of myelin sheath);GO:0021762(substantia nigra development);GO:0022010(central nervous system myelination);GO:0042552(myelination);GO:0042759(long-chain fatty acid biosynthetic process);GO:0043209(myelin sheath);GO:0048469(cell maturation);GO:0061564(axon development)	NA	NA	NA	proteolipid protein 1 [Source:HGNC Symbol;Acc:HGNC:9086]	2.74	4.04	1.61	17.37	10.03	26.36	0.2	-2.3	0.04	0.33	down	yes
MSTRG.28577	MORC4	ENST00000604604;MSTRG.28577.2;ENST00000355610;ENST00000255495;ENST00000478924	GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008270(zinc ion binding)	NA	NA	NA	MORC family CW-type zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:23485]	6.65	7.8	9.93	2.96	2.38	3.96	2.2	1.14	0.04	0.31	up	yes
MSTRG.28583	TSC22D3	ENST00000372390;ENST00000372397;ENST00000372383;ENST00000372382;ENST00000506081;ENST00000486554;ENST00000503515	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006970(response to osmotic stress);GO:0034220(ion transmembrane transport);GO:0043426(MRF binding);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0055085(transmembrane transport);GO:0070236(negative regulation of activation-induced cell death of T cells)"	NA	NA	NA	"TSC22 domain family, member 3 [Source:HGNC Symbol;Acc:HGNC:3051]"	7.49	7.79	6.05	1.78	2.07	3.6	2.78	1.47	0.02	0.26	up	yes
MSTRG.28605	AMOT	ENST00000371959;ENST00000304758;MSTRG.28605.3;MSTRG.28605.4;ENST00000524145;ENST00000371958;ENST00000462114	GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0001702(gastrulation with mouth forming second);GO:0001725(stress fiber);GO:0001726(ruffle);GO:0003365(establishment of cell polarity involved in ameboidal cell migration);GO:0004872(receptor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005884(actin filament);GO:0005923(bicellular tight junction);GO:0006935(chemotaxis);GO:0007043(cell-cell junction assembly);GO:0008180(COP9 signalosome);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016021(integral component of membrane);GO:0016525(negative regulation of angiogenesis);GO:0030027(lamellipodium);GO:0030036(actin cytoskeleton organization);GO:0030139(endocytic vesicle);GO:0030334(regulation of cell migration);GO:0031410(cytoplasmic vesicle);GO:0034260(negative regulation of GTPase activity);GO:0034613(cellular protein localization);GO:0035329(hippo signaling);GO:0040019(positive regulation of embryonic development);GO:0042074(cell migration involved in gastrulation);GO:0043116(negative regulation of vascular permeability);GO:0043532(angiostatin binding);GO:0043534(blood vessel endothelial cell migration);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045793(positive regulation of cell size);GO:0048514(blood vessel morphogenesis);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051496(positive regulation of stress fiber assembly)	NA	NA	NA	angiomotin [Source:HGNC Symbol;Acc:HGNC:17810]	2.45	2.3	1.6	7.76	6.24	4.07	0.4	-1.31	0.03	0.3	down	yes
MSTRG.28640	LONRF3	ENST00000304778;ENST00000481285;ENST00000371628;ENST00000439603;ENST00000472173;ENST00000422289	GO:0004176(ATP-dependent peptidase activity);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0008270(zinc ion binding)	NA	NA	NA	LON peptidase N-terminal domain and ring finger 3 [Source:HGNC Symbol;Acc:HGNC:21152]	3.66	3.26	4.03	1.22	1.45	1.37	2.07	1.05	0	0.15	up	yes
MSTRG.28658	RNF113A	ENST00000371442	GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)	NA	NA	NA	ring finger protein 113A [Source:HGNC Symbol;Acc:HGNC:12974]	33.65	30.3	27.52	10.92	11.4	17.58	2.59	1.37	0.01	0.23	up	yes
MSTRG.28698	UTP14A	ENST00000425117;MSTRG.28698.2;ENST00000394422;ENST00000427972;ENST00000498179	GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0044822(poly(A) RNA binding)	03008(Ribosome biogenesis in eukaryotes)	NA	NA	"UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) [Source:HGNC Symbol;Acc:HGNC:10665]"	9.39	11.38	15.88	23	27.94	22.7	0.48	-1.07	0.04	0.32	down	yes
MSTRG.28743	FAM122B	ENST00000370790;ENST00000343004;ENST00000298090;ENST00000478384;ENST00000486347;ENST00000465128;ENST00000493333;ENST00000611027	GO:0005581(collagen trimer)	NA	NA	NA	family with sequence similarity 122B [Source:HGNC Symbol;Acc:HGNC:30490]	2.29	2.01	2	10.08	8.59	4.16	0.32	-1.62	0.04	0.3	down	yes
MSTRG.28746	FAM127B	ENST00000391440;MSTRG.28746.2;ENST00000518153;ENST00000370775;ENST00000520964;ENST00000522309	GO:0005515(protein binding)	NA	NA	NA	"family with sequence similarity 127, member B [Source:HGNC Symbol;Acc:HGNC:24514]"	8.9	7.02	12.91	2.17	3.51	4.33	2.96	1.57	0.02	0.28	up	yes
MSTRG.28754	CT45A10	ENST00000487941;MSTRG.28754.1;MSTRG.28754.4;MSTRG.28754.5;ENST00000611668;ENST00000617981	NA	NA	NA	NA	"cancer/testis antigen family 45, member A10 [Source:HGNC Symbol;Acc:HGNC:51263]"	15.26	13.91	11.24	3.37	2.95	3.76	3.49	1.8	0	0.17	up	yes
MSTRG.28757	CT45A8	MSTRG.28757.1;ENST00000611660;ENST00000611438	NA	NA	NA	NA	"cancer/testis antigen family 45, member A8 [Source:HGNC Symbol;Acc:HGNC:51261]"	3.07	1.39	1.86	0.67	0.57	0.37	2.26	1.18	0.03	0.28	up	yes
MSTRG.28780	FTH1P8	ENST00000498161	NA	NA	NA	NA	NA	10.6	9.41	12.19	1.83	0	0	6.33	2.66	0.02	0.28	up	yes
MSTRG.28799	CD99L2	ENST00000346693;ENST00000370377;ENST00000355149;ENST00000437787;ENST00000613030;ENST00000466436;ENST00000418547;ENST00000491877	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0016021(integral component of membrane)	NA	NA	NA	CD99 molecule-like 2 [Source:HGNC Symbol;Acc:HGNC:18237]	2.1	5.3	2.45	9.02	9.35	12.44	0.31	-1.69	0.03	0.29	down	yes
MSTRG.28827	ZNF185	MSTRG.28827.1;MSTRG.28827.2;ENST00000318504;ENST00000449285;ENST00000535861;ENST00000539731;MSTRG.28827.7;ENST00000370268;ENST00000370270;ENST00000436731;ENST00000318529;ENST00000426821;MSTRG.28827.15;ENST00000454925	GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0008270(zinc ion binding);GO:0015629(actin cytoskeleton)	NA	NA	NA	zinc finger protein 185 (LIM domain) [Source:HGNC Symbol;Acc:HGNC:12976]	6.86	6.51	6.32	1.56	1.42	1.64	3.04	1.61	0	0.08	up	yes
MSTRG.28828	PNMA5	ENST00000439251;ENST00000535214;ENST00000437210	GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process)	NA	NA	NA	paraneoplastic Ma antigen family member 5 [Source:HGNC Symbol;Acc:HGNC:18743]	10.44	7.52	8.48	2.14	2.18	2.15	3.42	1.77	0	0.11	up	yes
MSTRG.28847	HCFC1	ENST00000310441;ENST00000444191;ENST00000369984;MSTRG.28847.4;ENST00000461098	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000123(histone acetyltransferase complex);GO:0001205(RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006325(chromatin organization);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006996(organelle organization);GO:0007005(mitochondrion organization);GO:0007049(cell cycle);GO:0010628(positive regulation of gene expression);GO:0016020(membrane);GO:0019046(release from viral latency);GO:0030424(axon);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0043025(neuronal cell body);GO:0043254(regulation of protein complex assembly);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0048188(Set1C/COMPASS complex);GO:0050821(protein stabilization);GO:0070461(SAGA-type complex);GO:0070688(MLL5-L complex);GO:0071339(MLL1 complex);GO:0071407(cellular response to organic cyclic compound)"	NA	NA	NA	host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]	5.16	5.15	5.21	12.5	11.37	8.19	0.49	-1.04	0.01	0.24	down	yes
MSTRG.28854	RENBP	ENST00000393700;ENST00000457282;ENST00000369997;MSTRG.28854.5;ENST00000442361;ENST00000462086;ENST00000464227;ENST00000471056;ENST00000475904	GO:0003824(catalytic activity);GO:0004857(enzyme inhibitor activity);GO:0004866(endopeptidase inhibitor activity);GO:0005524(ATP binding);GO:0006044(N-acetylglucosamine metabolic process);GO:0006051(N-acetylmannosamine metabolic process);GO:0008217(regulation of blood pressure);GO:0010951(negative regulation of endopeptidase activity);GO:0017076(purine nucleotide binding);GO:0019262(N-acetylneuraminate catabolic process);GO:0042803(protein homodimerization activity);GO:0043086(negative regulation of catalytic activity);GO:0050121(N-acylglucosamine 2-epimerase activity);GO:0070062(extracellular exosome)	00520(Amino sugar and nucleotide sugar metabolism)	NA	NA	renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959]	7.7	7.25	11.98	1.13	0.36	1.69	5.11	2.35	0.02	0.26	up	yes
MSTRG.28857	MECP2	ENST00000303391;ENST00000619732;ENST00000453960;ENST00000628176;ENST00000407218;ENST00000622433;ENST00000486506;ENST00000611468;ENST00000369957;ENST00000631210;ENST00000481807;ENST00000488293;ENST00000463644;ENST00000625300;ENST00000626422;ENST00000630151;ENST00000627864;ENST00000629277	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000792(heterochromatin);GO:0001662(behavioral fear response);GO:0001666(response to hypoxia);GO:0001964(startle response);GO:0001976(neurological system process involved in regulation of systemic arterial blood pressure);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006020(inositol metabolic process);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0006342(chromatin silencing);GO:0006349(regulation of gene expression by genetic imprinting);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006541(glutamine metabolic process);GO:0006576(cellular biogenic amine metabolic process);GO:0007268(synaptic transmission);GO:0007416(synapse assembly);GO:0007420(brain development);GO:0007585(respiratory gaseous exchange);GO:0007612(learning);GO:0007613(memory);GO:0007616(long-term memory);GO:0007626(locomotory behavior);GO:0008104(protein localization);GO:0008134(transcription factor binding);GO:0008211(glucocorticoid metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0008327(methyl-CpG binding);GO:0008344(adult locomotory behavior);GO:0008542(visual learning);GO:0009314(response to radiation);GO:0009405(pathogenesis);GO:0009791(post-embryonic development);GO:0010385(double-stranded methylated DNA binding);GO:0010468(regulation of gene expression);GO:0016358(dendrite development);GO:0016571(histone methylation);GO:0016573(histone acetylation);GO:0019230(proprioception);GO:0019233(sensory perception of pain);GO:0019904(protein domain specific binding);GO:0021549(cerebellum development);GO:0021591(ventricular system development);GO:0030182(neuron differentiation);GO:0031061(negative regulation of histone methylation);GO:0031175(neuron projection development);GO:0032048(cardiolipin metabolic process);GO:0033555(multicellular organismal response to stress);GO:0035067(negative regulation of histone acetylation);GO:0035176(social behavior);GO:0035197(siRNA binding);GO:0040029(regulation of gene expression, epigenetic);GO:0042551(neuron maturation);GO:0042826(histone deacetylase binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0044822(poly(A) RNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046470(phosphatidylcholine metabolic process);GO:0047485(protein N-terminus binding);GO:0048167(regulation of synaptic plasticity);GO:0050432(catecholamine secretion);GO:0050884(neuromuscular process controlling posture);GO:0050905(neuromuscular process);GO:0051965(positive regulation of synapse assembly);GO:0060079(regulation of excitatory postsynaptic membrane potential);GO:0060291(long-term synaptic potentiation)"	NA	NA	NA	methyl CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990]	3.38	1.68	2.63	0.84	0.62	0.59	2.36	1.24	0.02	0.25	up	yes
MSTRG.28867	DNASE1L1	ENST00000369809;ENST00000393638;ENST00000369807;ENST00000369808;ENST00000014935;ENST00000309585;ENST00000497242;ENST00000451865;ENST00000412184;ENST00000424626;ENST00000432135	"GO:0000737(DNA catabolic process, endonucleolytic);GO:0003677(DNA binding);GO:0004520(endodeoxyribonuclease activity);GO:0004536(deoxyribonuclease activity);GO:0005634(nucleus);GO:0005783(endoplasmic reticulum);GO:0006259(DNA metabolic process);GO:0006308(DNA catabolic process);GO:0016888(endodeoxyribonuclease activity, producing 5'-phosphomonoesters);GO:0070062(extracellular exosome)"	NA	NA	NA	deoxyribonuclease I-like 1 [Source:HGNC Symbol;Acc:HGNC:2957]	9.23	11.07	7.89	3.12	3.21	4.61	2.3	1.2	0.02	0.27	up	yes
MSTRG.28874	SLC10A3	ENST00000369649;ENST00000263512;ENST00000393586;MSTRG.28874.4;ENST00000393587;ENST00000453912	GO:0005887(integral component of plasma membrane);GO:0008508(bile acid:sodium symporter activity);GO:0010033(response to organic substance);GO:0015721(bile acid and bile salt transport);GO:0016020(membrane);GO:0032526(response to retinoic acid);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 10, member 3 [Source:HGNC Symbol;Acc:HGNC:22979]"	0.38	3.25	3.99	7.55	6.11	4.11	0.26	-1.92	0.03	0.29	down	yes
MSTRG.2890	RP13-463N16.6	MSTRG.2890.1;ENST00000478294;MSTRG.2890.3;MSTRG.2890.4	NA	NA	NA	NA	NA	0.26	0.32	0.41	2.38	4.67	1.88	0.34	-1.56	0.04	0.31	down	yes
MSTRG.28923	AC134878.1	MSTRG.28923.1;MSTRG.28923.2	NA	NA	NA	NA	NA	0.59	0.5	1.21	2.77	2.67	1.79	0.48	-1.05	0.04	0.33	down	yes
MSTRG.2926	PROSER2	MSTRG.2926.1;ENST00000474155;MSTRG.2926.3;ENST00000277570;ENST00000444604;ENST00000379200	NA	NA	NA	NA	proline and serine rich 2 [Source:HGNC Symbol;Acc:HGNC:23728]	4.9	4.25	3.03	1.48	1.47	2.67	2.04	1.03	0.04	0.32	up	yes
MSTRG.2932	DHTKD1	ENST00000263035;ENST00000437298;ENST00000465617;ENST00000415935;ENST00000448829;ENST00000479283	"GO:0002244(hematopoietic progenitor cell differentiation);GO:0004591(oxoglutarate dehydrogenase (succinyl-transferring) activity);GO:0005739(mitochondrion);GO:0006091(generation of precursor metabolites and energy);GO:0006096(glycolytic process);GO:0006099(tricarboxylic acid cycle);GO:0008152(metabolic process);GO:0016624(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor);GO:0030976(thiamine pyrophosphate binding);GO:0045252(oxoglutarate dehydrogenase complex);GO:0055114(oxidation-reduction process)"	NA	NA	NA	dehydrogenase E1 and transketolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23537]	3.26	2.55	4.45	8.31	8.66	7.01	0.49	-1.02	0.04	0.31	down	yes
MSTRG.2942	OPTN	ENST00000263036;ENST00000378764;MSTRG.2942.3;ENST00000487935;ENST00000482140;ENST00000378757;ENST00000430081;ENST00000378748;ENST00000378752;ENST00000378747;ENST00000486862;ENST00000424614;ENST00000469025	GO:0000042(protein targeting to Golgi);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000139(Golgi membrane);GO:0000278(mitotic cell cycle);GO:0001155(TFIIIA-class transcription factor binding);GO:0001920(negative regulation of receptor recycling);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005776(autophagosome);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0007030(Golgi organization);GO:0007165(signal transduction);GO:0008022(protein C-terminus binding);GO:0008219(cell death);GO:0008284(positive regulation of cell proliferation);GO:0016023(cytoplasmic membrane-bounded vesicle);GO:0016236(macroautophagy);GO:0017137(Rab GTPase binding);GO:0031410(cytoplasmic vesicle);GO:0031593(polyubiquitin binding);GO:0034613(cellular protein localization);GO:0042060(wound healing);GO:0042802(identical protein binding);GO:0043001(Golgi to plasma membrane protein transport);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0050663(cytokine secretion);GO:0050829(defense response to Gram-negative bacterium);GO:0051260(protein homooligomerization);GO:0055037(recycling endosome);GO:0070530(K63-linked polyubiquitin binding);GO:0090161(Golgi ribbon formation)	NA	NA	NA	optineurin [Source:HGNC Symbol;Acc:HGNC:17142]	39.06	36.55	41.87	5	4.04	5.56	7.08	2.82	0	0.11	up	yes
MSTRG.2944	MCM10	ENST00000378714;ENST00000479669;ENST00000484800;ENST00000378694;ENST00000459751;ENST00000481292;ENST00000485659	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003688(DNA replication origin binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0008283(cell proliferation);GO:0031298(replication fork protection complex);GO:0042802(identical protein binding);GO:0046872(metal ion binding)	NA	NA	NA	minichromosome maintenance complex component 10 [Source:HGNC Symbol;Acc:HGNC:18043]	0.25	0.54	0.24	10.53	7.81	2.69	0.13	-2.93	0.01	0.24	down	yes
MSTRG.2946	SEPHS1	ENST00000327347;MSTRG.2946.2;ENST00000545675;MSTRG.2946.4;ENST00000378614;ENST00000413411;ENST00000425947;ENST00000494329	"GO:0003824(catalytic activity);GO:0004756(selenide, water dikinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005525(GTP binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006464(cellular protein modification process);GO:0008152(metabolic process);GO:0016310(phosphorylation);GO:0031965(nuclear membrane);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity)"	00450(Selenocompound metabolism);01100(Metabolic pathways)	NA	NA	selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685]	9.67	10.95	9.78	25.91	29.31	13.99	0.41	-1.29	0.05	0.33	down	yes
MSTRG.2969	SUV39H2	ENST00000378331;ENST00000433779;ENST00000378325;ENST00000354919;ENST00000313519;ENST00000420416;MSTRG.2969.7;MSTRG.2969.8;ENST00000412254	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0006333(chromatin assembly or disassembly);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0008168(methyltransferase activity);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0030154(cell differentiation);GO:0032259(methylation);GO:0034968(histone lysine methylation);GO:0036123(histone H3-K9 dimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0042754(negative regulation of circadian rhythm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0048511(rhythmic process);GO:0071456(cellular response to hypoxia)"	00310(Lysine degradation)	NA	NA	suppressor of variegation 3-9 homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:17287]	0.95	1.63	0.97	5.4	5	1.75	0.34	-1.56	0.04	0.31	down	yes
MSTRG.3022	OTUD1	ENST00000376495	GO:0004843(ubiquitin-specific protease activity);GO:0070536(protein K63-linked deubiquitination)	NA	NA	NA	OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346]	0	0	0	1.15	1.3	1.65	0.45	-1.16	0	0.15	down	yes
MSTRG.3029	PRTFDC1	ENST00000320152;ENST00000376378;ENST00000376376	GO:0000166(nucleotide binding);GO:0000287(magnesium ion binding);GO:0004422(hypoxanthine phosphoribosyltransferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006166(purine ribonucleoside salvage);GO:0009116(nucleoside metabolic process);GO:0042803(protein homodimerization activity)	NA	NA	NA	phosphoribosyl transferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23333]	2.54	3.32	3.31	8.15	4.79	6.32	0.47	-1.07	0.02	0.26	down	yes
MSTRG.3049	MASTL	ENST00000375946;ENST00000375940;ENST00000342386;ENST00000477034	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006468(protein phosphorylation);GO:0006974(cellular response to DNA damage stimulus);GO:0007067(mitotic nuclear division);GO:0007147(female meiosis II);GO:0016301(kinase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0032154(cleavage furrow);GO:0034048(negative regulation of protein phosphatase type 2A activity);GO:0051301(cell division);GO:0051487(activation of anaphase-promoting complex activity involved in meiotic cell cycle);GO:0051721(protein phosphatase 2A binding);GO:0051726(regulation of cell cycle)"	NA	NA	NA	microtubule associated serine/threonine kinase-like [Source:HGNC Symbol;Acc:HGNC:19042]	1.86	3.03	1.83	9.43	7.55	2.74	0.32	-1.64	0.04	0.33	down	yes
MSTRG.3051	ACBD5	ENST00000396271;ENST00000375897;ENST00000375901;ENST00000375905;ENST00000375888;ENST00000476758;ENST00000426079;ENST00000412279	GO:0000062(fatty-acyl-CoA binding);GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0006810(transport);GO:0008289(lipid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030242(peroxisome degradation);GO:0043231(intracellular membrane-bounded organelle)	NA	NA	NA	acyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23338]	10.69	14.84	9.4	4.8	4.32	2.82	2.09	1.06	0.02	0.28	up	yes
MSTRG.3116	FZD8	ENST00000374694	GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0001934(positive regulation of protein phosphorylation);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016055(Wnt signaling pathway);GO:0017147(Wnt-protein binding);GO:0030165(PDZ domain binding);GO:0030182(neuron differentiation);GO:0031625(ubiquitin protein ligase binding);GO:0033077(T cell differentiation in thymus);GO:0035567(non-canonical Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0043507(positive regulation of JUN kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060070(canonical Wnt signaling pathway)	04310(Wnt signaling pathway);04916(Melanogenesis);05200(Pathways in cancer);05217(Basal cell carcinoma)	NA	NA	frizzled class receptor 8 [Source:HGNC Symbol;Acc:HGNC:4046]	0	0	0.79	3.19	3.79	4.5	0.27	-1.91	0.02	0.27	down	yes
MSTRG.3117	NAMPTP1	ENST00000440465	NA	NA	K00763	6.3.4.21	NA	32.18	31.55	59.18	2.86	2.87	1.85	10.58	3.4	0	0.19	up	yes
MSTRG.3139	.	MSTRG.3139.1	NA	NA	NA	NA	NA	4.02	3.24	3.29	1.27	1.07	0.34	2.28	1.19	0.04	0.32	up	yes
MSTRG.3246	ZWINT	ENST00000373944;ENST00000494312;ENST00000395405;ENST00000318387;ENST00000489649;ENST00000460654;ENST00000361148;ENST00000478181;ENST00000467523	GO:0000070(mitotic sister chromatid segregation);GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007093(mitotic cell cycle checkpoint);GO:0007264(small GTPase mediated signal transduction);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043231(intracellular membrane-bounded organelle);GO:0047485(protein N-terminus binding);GO:0051301(cell division);GO:0051649(establishment of localization in cell)	NA	NA	NA	ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195]	3.69	2.41	2.4	62.89	60.05	30.32	0.07	-3.79	0.01	0.19	down	yes
MSTRG.3255	SLC16A9	ENST00000395348;MSTRG.3255.2;ENST00000490066	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015293(symporter activity);GO:0015718(monocarboxylic acid transport);GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0046415(urate metabolic process);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 16, member 9 [Source:HGNC Symbol;Acc:HGNC:23520]"	2.58	2.1	2.51	0.35	0.35	0.52	2.62	1.39	0	0.1	up	yes
MSTRG.3281	DNAJC12	ENST00000225171;MSTRG.3281.2;ENST00000483798;ENST00000480963;ENST00000339758;ENST00000480180	NA	NA	NA	NA	"DnaJ (Hsp40) homolog, subfamily C, member 12 [Source:HGNC Symbol;Acc:HGNC:28908]"	8.28	9.72	9.33	3.29	3.37	5.29	2.14	1.1	0.03	0.28	up	yes
MSTRG.33	MTND2P28	ENST00000457540	NA	NA	NA	NA	NA	56.19	37.61	30.93	336.73	367.53	229.2	0.14	-2.8	0.01	0.22	down	yes
MSTRG.3305	KIF1BP	ENST00000361983;ENST00000625461;ENST00000627949;ENST00000481912	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0006839(mitochondrial transport);GO:0007399(nervous system development);GO:0019894(kinesin binding);GO:0030154(cell differentiation)	NA	NA	NA	KIF1 binding protein [Source:HGNC Symbol;Acc:HGNC:23419]	3.49	4.65	6.04	12.68	12.82	6.48	0.4	-1.33	0.04	0.32	down	yes
MSTRG.3327	UNC5B	ENST00000335350;ENST00000373192	GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0012501(programmed cell death);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016021(integral component of membrane);GO:0033564(anterior/posterior axon guidance);GO:0043524(negative regulation of neuron apoptotic process);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)	04360(Axon guidance)	NA	NA	unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:HGNC:12568]	11.39	8.96	8.91	0.07	0.05	0.08	10.9	3.45	0	0.08	up	yes
MSTRG.3328	UNC5B-AS1	ENST00000449737;ENST00000447119	NA	NA	NA	NA	NA	1.34	2.24	1.43	0.06	0	0	2.29	1.19	0	0.17	up	yes
MSTRG.3340	DDIT4	ENST00000307365;ENST00000473155;ENST00000471240	GO:0001666(response to hypoxia);GO:0001764(neuron migration);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007420(brain development);GO:0008283(cell proliferation);GO:0009968(negative regulation of signal transduction);GO:0010467(gene expression);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030182(neuron differentiation);GO:0032007(negative regulation of TOR signaling);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043241(protein complex disassembly);GO:0045820(negative regulation of glycolytic process);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0051607(defense response to virus);GO:0071889(14-3-3 protein binding);GO:0072593(reactive oxygen species metabolic process);GO:1901216(positive regulation of neuron death);GO:1902532(negative regulation of intracellular signal transduction)	04150(mTOR signaling pathway)	NA	NA	DNA-damage-inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944]	621.94	593.85	721.87	10.37	12.02	187.44	41.57	5.38	0.05	0.34	up	yes
MSTRG.3365	MRPS16	ENST00000469143;MSTRG.3365.2;MSTRG.3365.4;ENST00000372950;ENST00000479005;ENST00000372945;ENST00000372940;ENST00000471251;ENST00000473427	GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005763(mitochondrial small ribosomal subunit);GO:0005840(ribosome);GO:0006412(translation);GO:0006996(organelle organization);GO:0032543(mitochondrial translation);GO:0070124(mitochondrial translational initiation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)	NA	NA	NA	mitochondrial ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:14048]	10.91	13.72	14.18	25.58	27.29	18.92	0.49	-1.04	0.01	0.23	down	yes
MSTRG.3483	GHITM	ENST00000372134;ENST00000618907	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006915(apoptotic process);GO:0008150(biological_process);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	NA	NA	NA	growth hormone inducible transmembrane protein [Source:HGNC Symbol;Acc:HGNC:17281]	221.49	233.64	208.95	66.12	80.9	47.72	3.18	1.67	0.01	0.23	up	yes
MSTRG.3512	PAPSS2	ENST00000361175;ENST00000456849;ENST00000465996;MSTRG.3512.4;ENST00000482258;MSTRG.3512.6	NA	NA	NA	NA	NA	34.47	24.08	20.53	12.1	11.76	14.21	2.31	1.21	0.01	0.24	up	yes
MSTRG.3544	RP11-236B18.5	MSTRG.3544.1	NA	NA	NA	NA	NA	0	0	0	1.37	0.79	1.97	0.45	-1.16	0.03	0.29	down	yes
MSTRG.357	MFAP2	ENST00000375534;ENST00000490075;ENST00000375535;MSTRG.357.4;ENST00000476788;ENST00000478684;ENST00000492598	GO:0001527(microfibril);GO:0001968(fibronectin binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030198(extracellular matrix organization);GO:0030220(platelet formation);GO:0048048(embryonic eye morphogenesis);GO:0048050(post-embryonic eye morphogenesis);GO:0070051(fibrinogen binding)	NA	NA	NA	microfibrillar-associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033]	1.85	2.03	3.23	0.16	0.35	0.43	2.6	1.38	0.02	0.25	up	yes
MSTRG.361	RCC2	ENST00000375436;MSTRG.361.1;MSTRG.361.3;MSTRG.361.4;ENST00000474892;ENST00000375433;MSTRG.361.7	NA	NA	NA	NA	NA	20.57	21.81	25.31	70.02	70.72	61.9	0.33	-1.62	0	0.14	down	yes
MSTRG.3618	AVPI1	MSTRG.3618.1;ENST00000370626	GO:0000187(activation of MAPK activity);GO:0005515(protein binding);GO:0007049(cell cycle)	NA	NA	NA	arginine vasopressin-induced 1 [Source:HGNC Symbol;Acc:HGNC:30898]	70.6	20.28	49.04	1.27	4.97	6.07	19.02	4.25	0	0.13	up	yes
MSTRG.3619	AVPI1	MSTRG.3619.1	NA	NA	NA	NA	NA	1.53	1.76	0.89	0.05	0.15	0.2	2.13	1.09	0.02	0.27	up	yes
MSTRG.3635	DNMBP	ENST00000543621;ENST00000324109;ENST00000472036;ENST00000422692	GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005795(Golgi stack);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0035023(regulation of Rho protein signal transduction);GO:0035556(intracellular signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0045202(synapse)	NA	NA	NA	dynamin binding protein [Source:HGNC Symbol;Acc:HGNC:30373]	2.67	3.24	3.37	8.11	7.68	5.75	0.44	-1.17	0	0.17	down	yes
MSTRG.3672	FBXW4	ENST00000470093;MSTRG.3672.1;ENST00000331272;ENST00000482428;ENST00000457105;ENST00000489578	GO:0000151(ubiquitin ligase complex);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016055(Wnt signaling pathway);GO:0030326(embryonic limb morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0051216(cartilage development);GO:0060173(limb development)	NA	NA	NA	F-box and WD repeat domain containing 4 [Source:HGNC Symbol;Acc:HGNC:10847]	9.06	7.71	7.29	2.73	3.18	4.09	2.39	1.26	0	0.16	up	yes
MSTRG.369	MRTO4	ENST00000330263;ENST00000493700;MSTRG.369.2;ENST00000479559	GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0031965(nuclear membrane);GO:0042254(ribosome biogenesis);GO:0044822(poly(A) RNA binding)	NA	NA	NA	mRNA turnover 4 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:18477]	8.13	8.62	13.21	25.15	27.97	22.59	0.39	-1.36	0.02	0.27	down	yes
MSTRG.3707	AS3MT	ENST00000339834;ENST00000369883;ENST00000478833;ENST00000615257;ENST00000369880	GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0009404(toxin metabolic process);GO:0018872(arsonoacetate metabolic process);GO:0030791(arsenite methyltransferase activity);GO:0030792(methylarsonite methyltransferase activity);GO:0032259(methylation)	NA	NA	NA	arsenite methyltransferase [Source:HGNC Symbol;Acc:HGNC:17452]	0.63	1.35	0.97	3.33	3.61	2.06	0.41	-1.3	0.01	0.2	down	yes
MSTRG.3749	SMNDC1	ENST00000369603;ENST00000369592;ENST00000460483;ENST00000471297;ENST00000477763	"GO:0000245(spliceosomal complex assembly);GO:0000375(RNA splicing, via transesterification reactions);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0006915(apoptotic process);GO:0008380(RNA splicing);GO:0015030(Cajal body);GO:0016607(nuclear speck);GO:0044822(poly(A) RNA binding);GO:0045111(intermediate filament cytoskeleton)"	03040(Spliceosome)	NA	NA	survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16900]	19.26	8.18	12.32	4.63	4.49	2.6	3.32	1.73	0.04	0.33	up	yes
MSTRG.3751	DUSP5	ENST00000369583;ENST00000468749	GO:0000188(inactivation of MAPK activity);GO:0001706(endoderm formation);GO:0004725(protein tyrosine phosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016311(dephosphorylation);GO:0016791(phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation)	04010(MAPK signaling pathway)	NA	NA	dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071]	20.81	24.15	14.85	4.68	6.31	6.5	3.17	1.66	0.02	0.25	up	yes
MSTRG.3765	GPAM	ENST00000348367;MSTRG.3765.3;MSTRG.3765.2;ENST00000369425;ENST00000480130	"GO:0004366(glycerol-3-phosphate O-acyltransferase activity);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005743(mitochondrial inner membrane);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0006637(acyl-CoA metabolic process);GO:0006641(triglyceride metabolic process);GO:0006644(phospholipid metabolic process);GO:0006650(glycerophospholipid metabolic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0008152(metabolic process);GO:0008374(O-acyltransferase activity);GO:0008654(phospholipid biosynthetic process);GO:0009749(response to glucose);GO:0016021(integral component of membrane);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0016746(transferase activity, transferring acyl groups);GO:0019432(triglyceride biosynthetic process);GO:0040018(positive regulation of multicellular organism growth);GO:0042104(positive regulation of activated T cell proliferation);GO:0044255(cellular lipid metabolic process);GO:0044281(small molecule metabolic process);GO:0046474(glycerophospholipid biosynthetic process);GO:0050707(regulation of cytokine secretion);GO:0051607(defense response to virus);GO:0055089(fatty acid homeostasis);GO:0055091(phospholipid homeostasis);GO:0070236(negative regulation of activation-induced cell death of T cells);GO:0070970(interleukin-2 secretion)"	00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);01100(Metabolic pathways)	NA	NA	"glycerol-3-phosphate acyltransferase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:24865]"	1.04	1.59	1.46	3.86	3.27	1.7	0.49	-1.03	0.02	0.28	down	yes
MSTRG.3775	CASP7	ENST00000621345;ENST00000429617;ENST00000369331;ENST00000345633;ENST00000369321;ENST00000614447;ENST00000369318;ENST00000369315;ENST00000621607;ENST00000452490;ENST00000468790;ENST00000487232	GO:0004190(aspartic-type endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0006921(cellular component disassembly involved in execution phase of apoptosis);GO:0007507(heart development);GO:0008234(cysteine-type peptidase activity);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0009411(response to UV);GO:0012501(programmed cell death);GO:0016485(protein processing);GO:0051402(neuron apoptotic process);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis)	04210(Apoptosis);05010(Alzheimer's disease)	NA	NA	"caspase 7, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:1508]"	6.86	7.01	4.07	2.31	2.24	1.77	2.14	1.1	0.04	0.33	up	yes
MSTRG.3786	AFAP1L2	MSTRG.3786.1;ENST00000304129;ENST00000369271;ENST00000491814;ENST00000419268;ENST00000483496	"GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0007346(regulation of mitotic cell cycle);GO:0009967(positive regulation of signal transduction);GO:0017124(SH3 domain binding);GO:0030296(protein tyrosine kinase activator activity);GO:0032675(regulation of interleukin-6 production);GO:0032757(positive regulation of interleukin-8 production);GO:0035591(signaling adaptor activity);GO:0042169(SH2 domain binding);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0061098(positive regulation of protein tyrosine kinase activity)"	NA	NA	NA	actin filament associated protein 1-like 2 [Source:HGNC Symbol;Acc:HGNC:25901]	0.2	0.2	0.16	3.38	2.15	6.38	0.28	-1.85	0.03	0.3	down	yes
MSTRG.381	CAMK2N1	ENST00000375078;ENST00000489020	GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0008427(calcium-dependent protein kinase inhibitor activity);GO:0014069(postsynaptic density);GO:0019901(protein kinase binding);GO:0030054(cell junction);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045202(synapse);GO:0045211(postsynaptic membrane)	NA	NA	NA	calcium/calmodulin-dependent protein kinase II inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:24190]	21.16	17.44	17.89	9.68	9.3	8.07	2.03	1.02	0.01	0.2	up	yes
MSTRG.3819	PRDX3	MSTRG.3819.1;ENST00000298510;ENST00000494433;ENST00000463322	GO:0000302(response to reactive oxygen species);GO:0001893(maternal placenta development);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005769(early endosome);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0008022(protein C-terminus binding);GO:0008284(positive regulation of cell proliferation);GO:0008379(thioredoxin peroxidase activity);GO:0008385(IkappaB kinase complex);GO:0008785(alkyl hydroperoxide reductase activity);GO:0016209(antioxidant activity);GO:0016491(oxidoreductase activity);GO:0018171(peptidyl-cysteine oxidation);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0030099(myeloid cell differentiation);GO:0032496(response to lipopolysaccharide);GO:0033673(negative regulation of kinase activity);GO:0034599(cellular response to oxidative stress);GO:0034614(cellular response to reactive oxygen species);GO:0042542(response to hydrogen peroxide);GO:0042744(hydrogen peroxide catabolic process);GO:0042802(identical protein binding);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043209(myelin sheath);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051881(regulation of mitochondrial membrane potential);GO:0051920(peroxiredoxin activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)	NA	NA	NA	peroxiredoxin 3 [Source:HGNC Symbol;Acc:HGNC:9354]	14.96	18.3	18.71	45.62	41.27	34.47	0.39	-1.37	0	0.13	down	yes
MSTRG.386	SH2D5	MSTRG.386.1;ENST00000375031;ENST00000460804;MSTRG.386.4;ENST00000444387;ENST00000518294;ENST00000517430;ENST00000519434	GO:0005515(protein binding);GO:0014069(postsynaptic density);GO:0030054(cell junction);GO:0045211(postsynaptic membrane)	NA	NA	NA	SH2 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28819]	1.85	2	2.24	0.29	0.38	0.78	2.18	1.12	0.01	0.23	up	yes
MSTRG.39	MTATP6P1	ENST00000514057	NA	NA	NA	NA	NA	142.66	107.71	92.04	350.44	338.2	313.54	0.37	-1.45	0.01	0.23	down	yes
MSTRG.3905	MKI67	MSTRG.3905.1;ENST00000368653;ENST00000368654;ENST00000617118;ENST00000464771;ENST00000484853;ENST00000478293	"GO:0000775(chromosome, centromeric region);GO:0000793(condensed chromosome);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006259(DNA metabolic process);GO:0007126(meiotic nuclear division);GO:0008022(protein C-terminus binding);GO:0008283(cell proliferation);GO:0014070(response to organic cyclic compound);GO:0016020(membrane);GO:0030212(hyaluronan metabolic process);GO:0031100(organ regeneration);GO:0034605(cellular response to heat);GO:0044822(poly(A) RNA binding);GO:0072574(hepatocyte proliferation);GO:1990705(cholangiocyte proliferation)"	NA	NA	NA	marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107]	0.86	0.81	0.28	36.53	28.61	4.29	0.06	-4.11	0.04	0.31	down	yes
MSTRG.3906	EBF3	MSTRG.3906.1;MSTRG.3906.2;MSTRG.3906.3;ENST00000368648;MSTRG.3906.5;ENST00000355311;ENST00000440978;MSTRG.3906.8	NA	NA	NA	NA	NA	0.98	1.28	0.82	4.94	3.71	6.08	0.34	-1.55	0.01	0.23	down	yes
MSTRG.3918	PWWP2B	ENST00000631148;ENST00000305233	GO:0005515(protein binding);GO:0005654(nucleoplasm)	NA	NA	NA	PWWP domain containing 2B [Source:HGNC Symbol;Acc:HGNC:25150]	3.87	2.78	3.14	0.66	0.59	1.09	2.77	1.47	0	0.15	up	yes
MSTRG.3968	IRF7	ENST00000348655;ENST00000397566;ENST00000397574;ENST00000533182;ENST00000397570;ENST00000469048;MSTRG.3968.7;ENST00000531912;ENST00000330243;ENST00000532326;ENST00000525750;ENST00000532788;ENST00000527160;ENST00000532096;ENST00000533190	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000975(regulatory region DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000982(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity);GO:0002224(toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0002819(regulation of adaptive immune response);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0009615(response to virus);GO:0010008(endosome membrane);GO:0016064(immunoglobulin mediated immune response);GO:0019043(establishment of viral latency);GO:0019221(cytokine-mediated signaling pathway);GO:0032479(regulation of type I interferon production);GO:0032481(positive regulation of type I interferon production);GO:0032607(interferon-alpha production);GO:0032608(interferon-beta production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0034127(regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0039530(MDA-5 signaling pathway);GO:0045087(innate immune response);GO:0045351(type I interferon biosynthetic process);GO:0045655(regulation of monocyte differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050776(regulation of immune response);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:2000110(negative regulation of macrophage apoptotic process)"	04620(Toll-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05160(Hepatitis C);05162(Measles);05164(Influenza A)	NA	NA	interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122]	4.7	4.12	6.31	0.89	0.92	0.85	3.23	1.69	0	0.18	up	yes
MSTRG.3979	SLC25A22	ENST00000320230;ENST00000628067;ENST00000531214;ENST00000481290;ENST00000627843;ENST00000630809;ENST00000531437;ENST00000532484;ENST00000529351;ENST00000533385;ENST00000531534;ENST00000531514;ENST00000625752;ENST00000456706;ENST00000524891;ENST00000629634;ENST00000625316;ENST00000527127;ENST00000525010;ENST00000532459;ENST00000525644;ENST00000629602;ENST00000530360	GO:0005313(L-glutamate transmembrane transporter activity);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006810(transport);GO:0015293(symporter activity);GO:0015813(L-glutamate transport);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0089711(L-glutamate transmembrane transport)	NA	NA	NA	"solute carrier family 25 (mitochondrial carrier: glutamate), member 22 [Source:HGNC Symbol;Acc:HGNC:19954]"	12.7	11.8	11.45	3.94	2.43	3.9	3.03	1.6	0.01	0.22	up	yes
MSTRG.4003	CTSD	ENST00000382123;ENST00000340134;MSTRG.4003.3;ENST00000482459;ENST00000427721;ENST00000236671;ENST00000433655;ENST00000429746;ENST00000497544;ENST00000438213;ENST00000367196	GO:0000045(autophagosome assembly);GO:0004175(endopeptidase activity);GO:0004190(aspartic-type endopeptidase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0006508(proteolysis);GO:0006914(autophagy);GO:0008233(peptidase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0022617(extracellular matrix disassembly);GO:0030163(protein catabolic process);GO:0030198(extracellular matrix organization);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0042277(peptide binding);GO:0042470(melanosome);GO:0043202(lysosomal lumen);GO:0045121(membrane raft);GO:0070062(extracellular exosome)	04142(Lysosome);05152(Tuberculosis)	NA	NA	cathepsin D [Source:HGNC Symbol;Acc:HGNC:2529]	74.74	57.41	65.72	33.62	30.03	48.82	2.09	1.06	0.02	0.27	up	yes
MSTRG.4005	AC068580.5	ENST00000446489	NA	NA	NA	NA	NA	4.88	3.51	4.51	0.24	0.49	0.23	4.41	2.14	0	0.13	up	yes
MSTRG.4009	MRPL23-AS1	ENST00000419080	NA	NA	NA	NA	NA	1.45	1.25	1.06	0.06	0.05	0.49	2.12	1.09	0.01	0.24	up	yes
MSTRG.4010	H19	ENST00000414790;ENST00000411861;ENST00000439725;MSTRG.4010.2;MSTRG.4010.3;ENST00000412788;ENST00000422826;ENST00000428066;ENST00000447298	NA	NA	NA	NA	NA	0.68	0.4	0.2	4.98	3.59	4.69	0.27	-1.87	0.01	0.19	down	yes
MSTRG.4021	SLC22A18	ENST00000347936;ENST00000312221;MSTRG.4021.3;ENST00000449793;ENST00000380574;ENST00000485423;ENST00000492567;ENST00000498244;ENST00000467719;ENST00000463571;ENST00000498209;ENST00000441077;ENST00000449603;ENST00000495518	GO:0005215(transporter activity);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006855(drug transmembrane transport);GO:0007588(excretion);GO:0015238(drug transmembrane transporter activity);GO:0015293(symporter activity);GO:0015695(organic cation transport);GO:0015893(drug transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016324(apical plasma membrane);GO:0031625(ubiquitin protein ligase binding);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 22, member 18 [Source:HGNC Symbol;Acc:HGNC:10964]"	3.57	2.42	2.1	0.32	0.29	1.06	2.96	1.57	0.01	0.23	up	yes
MSTRG.4023	NAP1L4	MSTRG.4023.2;MSTRG.4023.1;ENST00000620138;MSTRG.4023.7;MSTRG.4023.5;MSTRG.4023.6;MSTRG.4023.4;ENST00000380542;ENST00000469805;ENST00000469089;ENST00000526115;ENST00000492594;ENST00000526023;MSTRG.4023.14;ENST00000528363;ENST00000483643;ENST00000528261;ENST00000532325;ENST00000448187;ENST00000399614;ENST00000430811;ENST00000529361;ENST00000528968;ENST00000530064;ENST00000526842;ENST00000531291;ENST00000455338	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006334(nucleosome assembly);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0044822(poly(A) RNA binding);GO:0051082(unfolded protein binding)	NA	NA	NA	nucleosome assembly protein 1-like 4 [Source:HGNC Symbol;Acc:HGNC:7640]	10.84	12.37	13.03	27.79	29.09	17.21	0.45	-1.16	0.03	0.28	down	yes
MSTRG.4026	CARS	ENST00000380525;ENST00000531387;ENST00000397111;ENST00000484484;ENST00000278224;MSTRG.4026.6;MSTRG.4026.4;MSTRG.4026.5;ENST00000466442;ENST00000470221;ENST00000526890;ENST00000529772;MSTRG.4026.13;ENST00000465240;ENST00000439280;ENST00000465207;ENST00000524825;ENST00000527330	GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004817(cysteine-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006418(tRNA aminoacylation for protein translation);GO:0006423(cysteinyl-tRNA aminoacylation);GO:0010467(gene expression);GO:0042803(protein homodimerization activity);GO:0046872(metal ion binding)	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	cysteinyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:1493]	21.61	21.67	28.49	10.55	10	9.76	2.16	1.11	0.01	0.22	up	yes
MSTRG.4039	STIM1	ENST00000525403;ENST00000430222;MSTRG.4039.3;ENST00000300737;ENST00000616714;ENST00000527651;ENST00000532610;ENST00000532919;ENST00000530554;ENST00000525055;ENST00000528656;ENST00000532990;ENST00000526771;ENST00000527484;ENST00000533445;ENST00000533977;ENST00000526596;ENST00000533343;ENST00000531332;ENST00000526156;ENST00000534707	GO:0002020(protease binding);GO:0002115(store-operated calcium entry);GO:0005246(calcium channel regulator activity);GO:0005509(calcium ion binding);GO:0005513(detection of calcium ion);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005874(microtubule);GO:0005887(integral component of plasma membrane);GO:0006812(cation transport);GO:0006816(calcium ion transport);GO:0007596(blood coagulation);GO:0014902(myotube differentiation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0032237(activation of store-operated calcium channel activity);GO:0032541(cortical endoplasmic reticulum);GO:0042802(identical protein binding);GO:0043234(protein complex);GO:0051010(microtubule plus-end binding);GO:0051924(regulation of calcium ion transport);GO:0070166(enamel mineralization)	NA	NA	NA	stromal interaction molecule 1 [Source:HGNC Symbol;Acc:HGNC:11386]	19.91	22.46	16.12	6.51	6.89	6.12	2.61	1.38	0.01	0.19	up	yes
MSTRG.4099	PRKCDBP	MSTRG.4099.1;ENST00000532354;ENST00000303927;ENST00000524852;ENST00000530979	GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005901(caveola);GO:0030866(cortical actin cytoskeleton organization);GO:0032922(circadian regulation of gene expression);GO:0043234(protein complex);GO:0051898(negative regulation of protein kinase B signaling);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:1901003(negative regulation of fermentation)	NA	NA	NA	"protein kinase C, delta binding protein [Source:HGNC Symbol;Acc:HGNC:9400]"	16.75	10.8	11.56	35.38	34.73	28.73	0.45	-1.15	0.02	0.27	down	yes
MSTRG.411	CDC42	MSTRG.411.1;ENST00000400259;ENST00000344548;ENST00000315554;ENST00000498236;ENST00000411827	GO:0000139(Golgi membrane);GO:0000322(storage vacuole);GO:0001934(positive regulation of protein phosphorylation);GO:0002040(sprouting angiogenesis);GO:0003161(cardiac conduction system development);GO:0003334(keratinocyte development);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0006897(endocytosis);GO:0007015(actin filament organization);GO:0007030(Golgi organization);GO:0007088(regulation of mitotic nuclear division);GO:0007097(nuclear migration);GO:0007163(establishment or maintenance of cell polarity);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007264(small GTPase mediated signal transduction);GO:0007411(axon guidance);GO:0007596(blood coagulation);GO:0008152(metabolic process);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0015031(protein transport);GO:0016020(membrane);GO:0019901(protein kinase binding);GO:0021762(substantia nigra development);GO:0030036(actin cytoskeleton organization);GO:0030141(secretory granule);GO:0030175(filopodium);GO:0030225(macrophage differentiation);GO:0030496(midbody);GO:0030742(GTP-dependent protein binding);GO:0031069(hair follicle morphogenesis);GO:0031256(leading edge membrane);GO:0031274(positive regulation of pseudopodium assembly);GO:0031295(T cell costimulation);GO:0031333(negative regulation of protein complex assembly);GO:0031424(keratinization);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0031647(regulation of protein stability);GO:0031996(thioesterase binding);GO:0032467(positive regulation of cytokinesis);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034191(apolipoprotein A-I receptor binding);GO:0034332(adherens junction organization);GO:0034613(cellular protein localization);GO:0035088(establishment or maintenance of apical/basal cell polarity);GO:0035264(multicellular organism growth);GO:0036336(dendritic cell migration);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042176(regulation of protein catabolic process);GO:0042692(muscle cell differentiation);GO:0042802(identical protein binding);GO:0042995(cell projection);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043410(positive regulation of MAPK cascade);GO:0043497(regulation of protein heterodimerization activity);GO:0043525(positive regulation of neuron apoptotic process);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045087(innate immune response);GO:0045177(apical part of cell);GO:0045740(positive regulation of DNA replication);GO:0045859(regulation of protein kinase activity);GO:0046330(positive regulation of JNK cascade);GO:0046847(filopodium assembly);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0048554(positive regulation of metalloenzyme activity);GO:0048664(neuron fate determination);GO:0048730(epidermis morphogenesis);GO:0051017(actin filament bundle assembly);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051149(positive regulation of muscle cell differentiation);GO:0051233(spindle midzone);GO:0051246(regulation of protein metabolic process);GO:0051489(regulation of filopodium assembly);GO:0051647(nucleus localization);GO:0051683(establishment of Golgi localization);GO:0051835(positive regulation of synapse structural plasticity);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0060047(heart contraction);GO:0060070(canonical Wnt signaling pathway);GO:0060501(positive regulation of epithelial cell proliferation involved in lung morphogenesis);GO:0060661(submandibular salivary gland formation);GO:0060684(epithelial-mesenchymal cell signaling);GO:0060789(hair follicle placode formation);GO:0070062(extracellular exosome);GO:0071338(positive regulation of hair follicle cell proliferation);GO:0071944(cell periphery);GO:0072384(organelle transport along microtubule);GO:0072686(mitotic spindle);GO:0090135(actin filament branching);GO:0090136(epithelial cell-cell adhesion);GO:0090316(positive regulation of intracellular protein transport);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)	04010(MAPK signaling pathway);04062(Chemokine signaling pathway);04144(Endocytosis);04360(Axon guidance);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04660(T cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04722(Neurotrophin signaling pathway);04810(Regulation of actin cytoskeleton);04912(GnRH signaling pathway);05100(Bacterial invasion of epithelial cells);05120(Epithelial cell signaling in Helicobacter pylori infection);05130(Pathogenic Escherichia coli infection);05131(Shigellosis);05200(Pathways in cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer)	NA	NA	cell division cycle 42 [Source:HGNC Symbol;Acc:HGNC:1736]	32.86	67.93	60.74	92.12	96.14	61.35	0.45	-1.15	0.02	0.27	down	yes
MSTRG.4111	TPP1	ENST00000299427;ENST00000533371;ENST00000611494;ENST00000524611;ENST00000532191;ENST00000524924;ENST00000528807;ENST00000524788;ENST00000428886;ENST00000534644;ENST00000530040;ENST00000528917;ENST00000531754;ENST00000524903;ENST00000528657	GO:0004175(endopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0006508(proteolysis);GO:0006629(lipid metabolic process);GO:0007040(lysosome organization);GO:0007399(nervous system development);GO:0007417(central nervous system development);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0030163(protein catabolic process);GO:0030855(epithelial cell differentiation);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response);GO:0042277(peptide binding);GO:0042470(melanosome);GO:0043171(peptide catabolic process);GO:0043202(lysosomal lumen);GO:0044267(cellular protein metabolic process);GO:0045453(bone resorption);GO:0046872(metal ion binding);GO:0050885(neuromuscular process controlling balance);GO:0070062(extracellular exosome)	04142(Lysosome)	NA	NA	tripeptidyl peptidase I [Source:HGNC Symbol;Acc:HGNC:2073]	41.85	37.74	36.12	16.19	12.08	21.92	2.5	1.32	0.03	0.28	up	yes
MSTRG.4163	ADM	ENST00000278175;ENST00000534464;ENST00000530439;ENST00000524948;ENST00000528655;ENST00000526492;ENST00000525063;ENST00000528544	GO:0001570(vasculogenesis);GO:0001666(response to hypoxia);GO:0001843(neural tube closure);GO:0002026(regulation of the force of heart contraction);GO:0002031(G-protein coupled receptor internalization);GO:0005102(receptor binding);GO:0005179(hormone activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0006171(cAMP biosynthetic process);GO:0006701(progesterone biosynthetic process);GO:0007165(signal transduction);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007267(cell-cell signaling);GO:0007507(heart development);GO:0007565(female pregnancy);GO:0007568(aging);GO:0008015(blood circulation);GO:0008209(androgen metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0009409(response to cold);GO:0009611(response to wounding);GO:0010033(response to organic substance);GO:0010460(positive regulation of heart rate);GO:0019933(cAMP-mediated signaling);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031100(organ regeneration);GO:0031102(neuron projection regeneration);GO:0031623(receptor internalization);GO:0031700(adrenomedullin receptor binding);GO:0032496(response to lipopolysaccharide);GO:0032868(response to insulin);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042594(response to starvation);GO:0043065(positive regulation of apoptotic process);GO:0043116(negative regulation of vascular permeability);GO:0045766(positive regulation of angiogenesis);GO:0045906(negative regulation of vasoconstriction);GO:0045909(positive regulation of vasodilation);GO:0046879(hormone secretion);GO:0048589(developmental growth);GO:0051384(response to glucocorticoid);GO:0055074(calcium ion homeostasis);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060712(spongiotrophoblast layer development);GO:0097084(vascular smooth muscle cell development);GO:2001214(positive regulation of vasculogenesis)	NA	NA	NA	adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259]	38.56	22.29	28.35	7.96	7.18	2.64	4.51	2.17	0.05	0.34	up	yes
MSTRG.4189	MICAL2	ENST00000526065;MSTRG.4189.4;MSTRG.4189.5;MSTRG.4189.6;ENST00000256194;MSTRG.4189.8;ENST00000531732;ENST00000530823;ENST00000532420;ENST00000527546;ENST00000342902;ENST00000524685;ENST00000533389;ENST00000379612;ENST00000528931;ENST00000532166;ENST00000527195;ENST00000530691;ENST00000524730;ENST00000529562;ENST00000525216;ENST00000530021;ENST00000526604;ENST00000525444	"GO:0001947(heart looping);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0007010(cytoskeleton organization);GO:0007507(heart development);GO:0008270(zinc ion binding);GO:0010735(positive regulation of transcription via serum response element binding);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0019417(sulfur oxidation);GO:0030042(actin filament depolymerization);GO:0043914(NADPH:sulfur oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0071949(FAD binding)"	NA	NA	NA	"microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693]"	4.31	4.26	5.57	1.13	0.6	0.3	3.2	1.68	0.01	0.23	up	yes
MSTRG.421	LUZP1	MSTRG.421.1;MSTRG.421.3;MSTRG.421.4;MSTRG.421.6;MSTRG.421.5;ENST00000418342;ENST00000302291;ENST00000314174;ENST00000471849	GO:0003281(ventricular septum development);GO:0005634(nucleus);GO:0016020(membrane);GO:0021503(neural fold bending);GO:0060840(artery development);GO:0070062(extracellular exosome)	NA	NA	NA	leucine zipper protein 1 [Source:HGNC Symbol;Acc:HGNC:14985]	2.15	4.1	4.11	8.94	8.11	4.25	0.4	-1.32	0.02	0.26	down	yes
MSTRG.4234	SAAL1	MSTRG.4234.1;MSTRG.4234.2;ENST00000532403;MSTRG.4234.4;MSTRG.4234.5;ENST00000524803;ENST00000300013;ENST00000534721;ENST00000530436;ENST00000531751;ENST00000531581;ENST00000530237;ENST00000529318;ENST00000531216;ENST00000533851;ENST00000530180;ENST00000528002;ENST00000530736	GO:0005488(binding);GO:0005615(extracellular space)	NA	NA	NA	serum amyloid A-like 1 [Source:HGNC Symbol;Acc:HGNC:25158]	8.1	9.44	8.7	24.06	24.67	20.79	0.37	-1.42	0	0.11	down	yes
MSTRG.4246	LDHA	ENST00000422447;ENST00000543445;ENST00000469976;ENST00000545467;ENST00000430553;ENST00000396222;ENST00000535451;ENST00000494573;ENST00000539814;ENST00000543695;ENST00000536528;ENST00000541097;ENST00000545215;ENST00000227157;ENST00000478970;ENST00000495052;ENST00000540430;ENST00000379412;ENST00000542179;ENST00000486690;ENST00000537296;ENST00000460405;ENST00000375710;ENST00000538451	"GO:0001666(response to hypoxia);GO:0003824(catalytic activity);GO:0004457(lactate dehydrogenase activity);GO:0004459(L-lactate dehydrogenase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0006089(lactate metabolic process);GO:0006090(pyruvate metabolic process);GO:0006096(glycolytic process);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0019674(NAD metabolic process);GO:0019752(carboxylic acid metabolic process);GO:0019900(kinase binding);GO:0021762(substantia nigra development);GO:0031668(cellular response to extracellular stimulus);GO:0035686(sperm fibrous sheath);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0044237(cellular metabolic process);GO:0044281(small molecule metabolic process);GO:0048569(post-embryonic organ development);GO:0051287(NAD binding);GO:0051591(response to cAMP);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)"	00010(Glycolysis / Gluconeogenesis);00270(Cysteine and methionine metabolism);00620(Pyruvate metabolism);00640(Propanoate metabolism);01100(Metabolic pathways)	NA	NA	lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]	54.91	67.82	95.57	226.33	230.67	192.51	0.29	-1.77	0.01	0.23	down	yes
MSTRG.4265	E2F8	ENST00000527884;ENST00000620009;ENST00000250024;ENST00000529188;ENST00000532666	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0001890(placenta development);GO:0002040(sprouting angiogenesis);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005667(transcription factor complex);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008283(cell proliferation);GO:0032466(negative regulation of cytokinesis);GO:0032877(positive regulation of DNA endoreduplication);GO:0033301(cell cycle comprising mitosis without cytokinesis);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060707(trophoblast giant cell differentiation);GO:0060718(chorionic trophoblast cell differentiation);GO:0070365(hepatocyte differentiation)"	NA	NA	NA	E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727]	0.15	0.12	0.07	5.23	4.3	1.37	0.21	-2.27	0.02	0.28	down	yes
MSTRG.431	E2F2	ENST00000361729;ENST00000487237	"GO:0000278(mitotic cell cycle);GO:0001047(core promoter binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0051726(regulation of cell cycle);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:1990086(lens fiber cell apoptotic process)"	04110(Cell cycle);05200(Pathways in cancer);05212(Pancreatic cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05219(Bladder cancer);05220(Chronic myeloid leukemia);05222(Small cell lung cancer);05223(Non-small cell lung cancer)	NA	NA	E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114]	0.05	0.05	0.05	4.33	4	2.84	0.21	-2.27	0	0.13	down	yes
MSTRG.432	ID3	ENST00000374561;ENST00000463312;ENST00000486541	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001656(metanephros development);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006275(regulation of DNA replication);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organismal development);GO:0007417(central nervous system development);GO:0007507(heart development);GO:0007517(muscle organ development);GO:0007623(circadian rhythm);GO:0008134(transcription factor binding);GO:0009611(response to wounding);GO:0015630(microtubule cytoskeleton);GO:0019904(protein domain specific binding);GO:0030182(neuron differentiation);GO:0030855(epithelial cell differentiation);GO:0030903(notochord development);GO:0042476(odontogenesis);GO:0043065(positive regulation of apoptotic process);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045662(negative regulation of myoblast differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046983(protein dimerization activity);GO:0051726(regulation of cell cycle)"	04350(TGF-beta signaling pathway)	NA	NA	"inhibitor of DNA binding 3, dominant negative helix-loop-helix protein [Source:HGNC Symbol;Acc:HGNC:5362]"	19.93	15.75	18.4	46.62	60.2	58.3	0.39	-1.36	0	0.12	down	yes
MSTRG.4339	DEPDC7	ENST00000241051;ENST00000427755;MSTRG.4339.2;ENST00000532078;ENST00000311388;ENST00000616885	GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005622(intracellular);GO:0005829(cytosol);GO:0007264(small GTPase mediated signal transduction);GO:0008150(biological_process);GO:0035556(intracellular signal transduction);GO:0051056(regulation of small GTPase mediated signal transduction)	NA	NA	NA	DEP domain containing 7 [Source:HGNC Symbol;Acc:HGNC:29899]	25.94	36.31	39.83	13.06	8.8	4.95	2.62	1.39	0.03	0.28	up	yes
MSTRG.4344	CSTF3	ENST00000528865;ENST00000323959;ENST00000524827;ENST00000526480;ENST00000438862;ENST00000431742;ENST00000524556;ENST00000524775	"GO:0000398(mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006378(mRNA polyadenylation);GO:0006379(mRNA cleavage);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0031124(mRNA 3'-end processing);GO:0044822(poly(A) RNA binding)"	03015(mRNA surveillance pathway)	NA	NA	"cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa [Source:HGNC Symbol;Acc:HGNC:2485]"	1.45	2.7	3.9	8.51	10.07	4.77	0.32	-1.65	0.04	0.31	down	yes
MSTRG.4350	KIAA1549L	MSTRG.4350.1;MSTRG.4350.2;ENST00000526400;ENST00000321505;ENST00000265654	GO:0002230(positive regulation of defense response to virus by host);GO:0016021(integral component of membrane);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	NA	NA	NA	KIAA1549-like [Source:HGNC Symbol;Acc:HGNC:24836]	1.36	1.69	1.44	4.46	4.18	4.09	0.45	-1.16	0	0.08	down	yes
MSTRG.4353	CD59	ENST00000534431;MSTRG.4353.3;MSTRG.4353.2;ENST00000379011;ENST00000534312;ENST00000527926;ENST00000525763;ENST00000531145;MSTRG.4353.9;ENST00000533181;ENST00000395850;ENST00000533403;ENST00000351554;ENST00000528987;ENST00000415002;ENST00000445143;ENST00000426650;ENST00000437761;ENST00000527577;ENST00000528700	GO:0001848(complement binding);GO:0001971(negative regulation of activation of membrane attack complex);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0007596(blood coagulation);GO:0009986(cell surface);GO:0016020(membrane);GO:0030449(regulation of complement activation);GO:0031362(anchored component of external side of plasma membrane);GO:0031982(vesicle);GO:0042102(positive regulation of T cell proliferation);GO:0042383(sarcolemma);GO:0043066(negative regulation of apoptotic process);GO:0043218(compact myelin);GO:0045087(innate immune response);GO:0070062(extracellular exosome)	NA	NA	NA	"CD59 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:HGNC:1689]"	13.35	14.43	18.98	43.49	46.28	55.66	0.34	-1.55	0.01	0.22	down	yes
MSTRG.4381	COMMD9	ENST00000355500;ENST00000263401;ENST00000533308;ENST00000452374;ENST00000532705;ENST00000533643;ENST00000528608;ENST00000526789	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006814(sodium ion transport);GO:0016023(cytoplasmic membrane-bounded vesicle)"	NA	NA	NA	COMM domain containing 9 [Source:HGNC Symbol;Acc:HGNC:25014]	2.16	2.32	3.25	6.76	6.5	4.27	0.47	-1.1	0.03	0.28	down	yes
MSTRG.440	FUCA1	MSTRG.440.1;MSTRG.440.2;ENST00000374479;MSTRG.440.4	NA	NA	NA	NA	NA	2.8	2.61	3.38	7.86	7.53	7.31	0.45	-1.14	0	0.17	down	yes
MSTRG.4410	RP11-613D13.5	MSTRG.4410.1	NA	NA	NA	NA	NA	0.34	0.46	0.33	1.91	1.59	0.86	0.5	-1.01	0.02	0.25	down	yes
MSTRG.4419	CD82	ENST00000526958;ENST00000227155;ENST00000342935;ENST00000532544;ENST00000525210;ENST00000525898;ENST00000527737;ENST00000524704;ENST00000529853;ENST00000530601;ENST00000530931	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome)	NA	NA	NA	CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210]	7.52	5.82	6.02	2.17	1.82	3.7	2.54	1.34	0.02	0.25	up	yes
MSTRG.4440	RP11-425L10.1	ENST00000467930	NA	NA	NA	NA	NA	0	1.69	1.92	4.46	3.47	3.67	0.27	-1.87	0.03	0.28	down	yes
MSTRG.4460	ACP2	MSTRG.4460.1;ENST00000256997;ENST00000534752;ENST00000534448;ENST00000527256;ENST00000531004;ENST00000533929;ENST00000525230;ENST00000531547;ENST00000529663;ENST00000524769;ENST00000530453;ENST00000444355;ENST00000529788	GO:0001501(skeletal system development);GO:0001784(phosphotyrosine binding);GO:0003993(acid phosphatase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005764(lysosome);GO:0005765(lysosomal membrane);GO:0007040(lysosome organization);GO:0010033(response to organic substance);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016311(dephosphorylation);GO:0031410(cytoplasmic vesicle);GO:0043005(neuron projection);GO:0043202(lysosomal lumen);GO:0048102(autophagic cell death);GO:0070062(extracellular exosome)	00740(Riboflavin metabolism);04142(Lysosome)	NA	NA	"acid phosphatase 2, lysosomal [Source:HGNC Symbol;Acc:HGNC:123]"	2.41	1.8	3.18	6.85	5.85	4.86	0.49	-1.02	0.04	0.32	down	yes
MSTRG.4482	TRIM51	ENST00000449290;ENST00000244891	GO:0005515(protein binding);GO:0005622(intracellular);GO:0008270(zinc ion binding)	NA	NA	NA	tripartite motif-containing 51 [Source:HGNC Symbol;Acc:HGNC:19023]	0.05	0.18	0	1.09	1.62	1.9	0.45	-1.15	0.01	0.24	down	yes
MSTRG.4493	UBE2L6	ENST00000340573;ENST00000287156;ENST00000528275;ENST00000527022;ENST00000526659	GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0006464(cellular protein modification process);GO:0008152(metabolic process);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0019787(ubiquitin-like protein transferase activity);GO:0019941(modification-dependent protein catabolic process);GO:0019985(translesion synthesis);GO:0032020(ISG15-protein conjugation);GO:0032480(negative regulation of type I interferon production);GO:0042296(ISG15 transferase activity);GO:0045087(innate immune response)	04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease)	NA	NA	ubiquitin-conjugating enzyme E2L 6 [Source:HGNC Symbol;Acc:HGNC:12490]	8.2	7.22	9.99	1.68	2.91	4.91	3	1.59	0.03	0.28	up	yes
MSTRG.4516	PATL1	MSTRG.4516.3;MSTRG.4516.4;MSTRG.4516.5;ENST00000300146;MSTRG.4516.1;MSTRG.4516.2;ENST00000531919	"GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0000932(cytoplasmic mRNA processing body);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0008266(poly(U) RNA binding);GO:0010467(gene expression);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0030014(CCR4-NOT complex);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0034046(poly(G) binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0044822(poly(A) RNA binding)"	03018(RNA degradation)	NA	NA	protein associated with topoisomerase II homolog 1 (yeast) [Source:HGNC Symbol;Acc:HGNC:26721]	39.7	35.45	31.82	11.13	10.65	6.78	3.32	1.73	0.01	0.23	up	yes
MSTRG.4554	FADS2	ENST00000305885;ENST00000535723;ENST00000574708;ENST00000535307;MSTRG.4554.5;ENST00000257261;ENST00000522639;ENST00000522056;ENST00000517839;ENST00000518606;ENST00000278840;ENST00000517312;ENST00000521849;ENST00000521571;ENST00000355484;ENST00000543584;ENST00000523235;ENST00000522359	GO:0004768(stearoyl-CoA 9-desaturase activity);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0006629(lipid metabolic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0033559(unsaturated fatty acid metabolic process);GO:0036109(alpha-linolenic acid metabolic process);GO:0043651(linoleic acid metabolic process);GO:0044281(small molecule metabolic process);GO:0055114(oxidation-reduction process)	00592(alpha-Linolenic acid metabolism);01040(Biosynthesis of unsaturated fatty acids);03320(PPAR signaling pathway)	NA	NA	fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575]	6.13	3.34	4.91	23.18	22.68	13.68	0.29	-1.77	0.03	0.29	down	yes
MSTRG.4557	FADS3	ENST00000527697;ENST00000533676;ENST00000278829;MSTRG.4557.3;ENST00000529404;ENST00000527379;ENST00000525588;ENST00000534223;ENST00000526294;ENST00000414624;ENST00000620971;ENST00000534426;ENST00000529525	GO:0003674(molecular_function);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)	NA	NA	NA	fatty acid desaturase 3 [Source:HGNC Symbol;Acc:HGNC:3576]	5.99	3.16	7.24	1.39	1.56	1.92	2.94	1.55	0.02	0.26	up	yes
MSTRG.4558	RAB3IL1	ENST00000394836;MSTRG.4558.1;MSTRG.4558.2;ENST00000301773;ENST00000526200;ENST00000533136;ENST00000530888	GO:0005515(protein binding);GO:0015031(protein transport);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity)	NA	NA	NA	RAB3A interacting protein (rabin3)-like 1 [Source:HGNC Symbol;Acc:HGNC:9780]	6.01	10.15	9.36	2.87	2.68	3.26	2.05	1.04	0.02	0.27	up	yes
MSTRG.4560	FTH1	ENST00000529191;ENST00000529631;ENST00000530019;ENST00000273550;ENST00000532829;ENST00000620041;ENST00000534180;ENST00000526640;ENST00000532601;ENST00000534719;ENST00000533138;ENST00000529548	GO:0004322(ferroxidase activity);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005623(cell);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006880(intracellular sequestering of iron ion);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006898(receptor-mediated endocytosis);GO:0006955(immune response);GO:0008043(intracellular ferritin complex);GO:0008199(ferric iron binding);GO:0008285(negative regulation of cell proliferation);GO:0048147(negative regulation of fibroblast proliferation);GO:0055085(transmembrane transport);GO:0055114(oxidation-reduction process);GO:0060547(negative regulation of necrotic cell death);GO:0061024(membrane organization);GO:0070062(extracellular exosome)	00860(Porphyrin and chlorophyll metabolism);04978(Mineral absorption)	NA	NA	"ferritin, heavy polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:3976]"	1704.18	1253.28	1666.69	417.26	342.21	562.75	4.14	2.05	0.01	0.19	up	yes
MSTRG.4562	INCENP	ENST00000394818;ENST00000533896;ENST00000278849;MSTRG.4562.4;ENST00000528037;MSTRG.4562.7;MSTRG.4562.6;ENST00000528375;ENST00000531099	"GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000795(synaptonemal complex);GO:0000800(lateral element);GO:0000801(central element);GO:0000910(cytokinesis);GO:0005515(protein binding);GO:0005721(pericentric heterochromatin);GO:0005819(spindle);GO:0005829(cytosol);GO:0005874(microtubule);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007264(small GTPase mediated signal transduction);GO:0010369(chromocenter);GO:0030496(midbody);GO:0043234(protein complex)"	NA	NA	NA	inner centromere protein antigens 135/155kDa [Source:HGNC Symbol;Acc:HGNC:6058]	5.23	4.62	2.72	22.59	23.34	12.1	0.24	-2.07	0.03	0.28	down	yes
MSTRG.4575	EML3	MSTRG.4575.3;MSTRG.4575.5;MSTRG.4575.4;MSTRG.4575.1;MSTRG.4575.2;ENST00000278823;ENST00000524902;ENST00000527204;ENST00000531179;ENST00000531261;ENST00000526844;ENST00000532239;ENST00000439994;ENST00000394773;ENST00000394776;ENST00000278845;ENST00000460939;ENST00000494176;ENST00000529309;ENST00000494448;ENST00000533165;ENST00000483199;ENST00000524518;ENST00000526116;ENST00000462626;ENST00000438258;ENST00000466886;ENST00000466671	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005874(microtubule)	NA	NA	NA	echinoderm microtubule associated protein like 3 [Source:HGNC Symbol;Acc:HGNC:26666]	11.94	12.27	11.7	26.69	28.99	26.99	0.45	-1.14	0	0.1	down	yes
MSTRG.459	RSRP1	ENST00000243189;ENST00000569495;ENST00000498238;MSTRG.459.2;ENST00000566395;ENST00000565733;ENST00000568254;MSTRG.459.5;ENST00000473314;ENST00000570063;ENST00000564223;ENST00000475766;ENST00000491378;ENST00000431849;ENST00000568701;ENST00000561867;ENST00000568996;ENST00000450820;ENST00000568399;ENST00000562018;ENST00000567741;ENST00000566599	GO:0005515(protein binding)	NA	NA	NA	arginine/serine-rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]	16.01	9.97	10.4	1.6	3.43	1.46	5.1	2.35	0.01	0.23	up	yes
MSTRG.4600	SNHG1	MSTRG.4600.2;MSTRG.4600.1;ENST00000539921;ENST00000540725;ENST00000537925;ENST00000537068;ENST00000538654;ENST00000537869;ENST00000539975;ENST00000535076;ENST00000545440;ENST00000542112;ENST00000541615;ENST00000541578;ENST00000538266;ENST00000545688;ENST00000544550;ENST00000545920;ENST00000540865;ENST00000535689;ENST00000537024;ENST00000539303;ENST00000541416;ENST00000537965;ENST00000545308;ENST00000540904;ENST00000544983	NA	NA	NA	NA	NA	57.96	62.43	37.17	15.17	17.47	7.99	3.28	1.71	0.05	0.34	up	yes
MSTRG.4601	SLC3A2	ENST00000377890;ENST00000377891;ENST00000377889;ENST00000535296;ENST00000538084;ENST00000544377;ENST00000338663;ENST00000541372;ENST00000539458;ENST00000537508;ENST00000541649;ENST00000537839;ENST00000539891;ENST00000538682;ENST00000546253;ENST00000536981;ENST00000457660;ENST00000546312;ENST00000541425;ENST00000542922;ENST00000535768;ENST00000539507;ENST00000542793	GO:0003725(double-stranded RNA binding);GO:0003824(catalytic activity);GO:0005432(calcium:sodium antiporter activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0006865(amino acid transport);GO:0007596(blood coagulation);GO:0008152(metabolic process);GO:0009986(cell surface);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015827(tryptophan transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016049(cell growth);GO:0016324(apical plasma membrane);GO:0035725(sodium ion transmembrane transport);GO:0042470(melanosome);GO:0043169(cation binding);GO:0043330(response to exogenous dsRNA);GO:0044822(poly(A) RNA binding);GO:0050900(leukocyte migration);GO:0055085(transmembrane transport);GO:0060356(leucine import);GO:0070062(extracellular exosome)	04974(Protein digestion and absorption)	NA	NA	"solute carrier family 3 (amino acid transporter heavy chain), member 2 [Source:HGNC Symbol;Acc:HGNC:11026]"	305.02	293.33	257.28	48.9	42.31	25.2	6.47	2.69	0.01	0.19	up	yes
MSTRG.4605	PLA2G16	ENST00000323646;ENST00000415826;ENST00000394613;ENST00000540943	GO:0004623(phospholipase A2 activity);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006644(phospholipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0008970(phosphatidylcholine 1-acylhydrolase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016042(lipid catabolic process);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0044281(small molecule metabolic process);GO:0045786(negative regulation of cell cycle);GO:0046474(glycerophospholipid biosynthetic process);GO:0048471(perinuclear region of cytoplasm);GO:0052739(phosphatidylserine 1-acylhydrolase activity);GO:0052740(1-acyl-2-lysophosphatidylserine acylhydrolase activity)	NA	NA	NA	"phospholipase A2, group XVI [Source:HGNC Symbol;Acc:HGNC:17825]"	7.12	3.96	7.77	2.5	2.54	4.28	2.29	1.2	0.03	0.29	up	yes
MSTRG.4612	C11orf95	MSTRG.4612.1;ENST00000433688;ENST00000546282	NA	NA	NA	NA	chromosome 11 open reading frame 95 [Source:HGNC Symbol;Acc:HGNC:28449]	18.11	12.43	9	5	6.18	7.03	2.42	1.27	0.03	0.28	up	yes
MSTRG.4627	STIP1	ENST00000358794;ENST00000305218;ENST00000536973;ENST00000538945;ENST00000543847;ENST00000540736;ENST00000540501;ENST00000544739;ENST00000537479;ENST00000538497;ENST00000540887;ENST00000355603	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0006950(response to stress);GO:0008022(protein C-terminus binding);GO:0030544(Hsp70 protein binding);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0044822(poly(A) RNA binding);GO:0051087(chaperone binding)	05020(Prion diseases)	NA	NA	stress-induced phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11387]	48.89	54.95	52.94	100.76	129.05	79.86	0.48	-1.06	0.03	0.29	down	yes
MSTRG.4632	TRPT1	ENST00000394547;ENST00000394546;ENST00000541278;ENST00000546133;ENST00000536158;ENST00000539436;MSTRG.4632.7;ENST00000544286;ENST00000537907;ENST00000541928;ENST00000317459;ENST00000546089;ENST00000539595;ENST00000536234;ENST00000545812;ENST00000542040;ENST00000540472	"GO:0000215(tRNA 2'-phosphotransferase activity);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0008665(2'-phosphotransferase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0045859(regulation of protein kinase activity)"	NA	NA	NA	tRNA phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:20316]	9.5	7.29	8.46	3.64	4.07	6.97	2.02	1.02	0.02	0.27	up	yes
MSTRG.4653	PPP2R5B	ENST00000413292;MSTRG.4653.3;MSTRG.4653.2;MSTRG.4653.4;MSTRG.4653.5;ENST00000164133;ENST00000532850;ENST00000528530	GO:0000159(protein phosphatase type 2A complex);GO:0001932(regulation of protein phosphorylation);GO:0005488(binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0008601(protein phosphatase type 2A regulator activity);GO:0010469(regulation of receptor activity);GO:0010976(positive regulation of neuron projection development);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031334(positive regulation of protein complex assembly);GO:0031952(regulation of protein autophosphorylation);GO:0034047(regulation of protein phosphatase type 2A activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0044267(cellular protein metabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0051388(positive regulation of neurotrophin TRK receptor signaling pathway);GO:0070317(negative regulation of G0 to G1 transition);GO:0071158(positive regulation of cell cycle arrest);GO:0071363(cellular response to growth factor stimulus)	03015(mRNA surveillance pathway);04114(Oocyte meiosis);04310(Wnt signaling pathway)	NA	NA	"protein phosphatase 2, regulatory subunit B', beta [Source:HGNC Symbol;Acc:HGNC:9310]"	12.01	10.97	15.9	5.49	4.91	6.15	2.2	1.14	0.02	0.25	up	yes
MSTRG.4661	CDCA5	ENST00000529290;ENST00000525464;ENST00000275517;ENST00000524733;ENST00000404147;ENST00000479032;ENST00000531401;ENST00000527430;ENST00000462902	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006302(double-strand break repair);GO:0007064(mitotic sister chromatid cohesion);GO:0007067(mitotic nuclear division);GO:0007076(mitotic chromosome condensation);GO:0007080(mitotic metaphase plate congression);GO:0008278(cohesin complex);GO:0031536(positive regulation of exit from mitosis);GO:0051301(cell division);GO:0071922(regulation of cohesin localization to chromatin);GO:1901989(positive regulation of cell cycle phase transition)"	NA	NA	NA	cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626]	4.72	6.98	2.8	46.02	52.92	21.65	0.11	-3.16	0.01	0.24	down	yes
MSTRG.4662	CDCA5	MSTRG.4662.1	NA	NA	NA	NA	NA	0	0.09	0	1.26	1.39	1.11	0.44	-1.19	0	0.12	down	yes
MSTRG.4664	ZFPL1	MSTRG.4664.1;MSTRG.4664.2;ENST00000525509;ENST00000453524;ENST00000294258;ENST00000526289;ENST00000526440;ENST00000526334;ENST00000526791;ENST00000526945;ENST00000532200;ENST00000530488;ENST00000530744	"GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport)"	NA	NA	NA	zinc finger protein-like 1 [Source:HGNC Symbol;Acc:HGNC:12868]	21.75	15.52	19.1	8.18	6.58	7.62	2.53	1.34	0.01	0.2	up	yes
MSTRG.4672	POLA2	ENST00000265465;ENST00000527850;ENST00000532469;ENST00000527618;ENST00000525924;ENST00000533192;ENST00000534785	"GO:0000060(protein import into nucleus, translocation);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003674(molecular_function);GO:0003677(DNA binding);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005658(alpha DNA polymerase:primase complex);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006271(DNA strand elongation involved in DNA replication);GO:0032201(telomere maintenance via semi-conservative replication);GO:0046982(protein heterodimerization activity);GO:0071897(DNA biosynthetic process)"	NA	NA	NA	"polymerase (DNA directed), alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073]"	2.14	2.35	3.56	19.25	18.03	10.61	0.19	-2.43	0.01	0.2	down	yes
MSTRG.4677	DPF2	ENST00000528416;ENST00000444314;ENST00000530993;ENST00000252268;ENST00000524666;ENST00000532264;ENST00000532102;ENST00000530973;ENST00000532492;ENST00000532052;ENST00000531989	"GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0008270(zinc ion binding);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0090544(BAF-type complex);GO:0097190(apoptotic signaling pathway)"	NA	NA	NA	"D4, zinc and double PHD fingers family 2 [Source:HGNC Symbol;Acc:HGNC:9964]"	19.69	11.63	14.73	7.78	7.25	8.38	2.19	1.13	0.01	0.2	up	yes
MSTRG.4681	FRMD8	ENST00000317568;ENST00000531296;ENST00000528854;ENST00000533782;ENST00000355991;ENST00000416776;ENST00000526201;ENST00000525156;ENST00000531151	GO:0005515(protein binding);GO:0005856(cytoskeleton)	NA	NA	NA	FERM domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25462]	3.8	4.44	3.84	14.83	8.76	18.19	0.34	-1.55	0.04	0.31	down	yes
MSTRG.4704	CFL1	ENST00000530157;ENST00000525710;ENST00000525451;ENST00000530945;ENST00000308162;ENST00000527344;ENST00000531407;ENST00000524553;ENST00000534769;ENST00000531413;ENST00000532134;ENST00000530413;ENST00000534784;ENST00000526975	GO:0000281(mitotic cytokinesis);GO:0001755(neural crest cell migration);GO:0001842(neural fold formation);GO:0002576(platelet degranulation);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005911(cell-cell junction);GO:0005925(focal adhesion);GO:0006468(protein phosphorylation);GO:0007010(cytoskeleton organization);GO:0007015(actin filament organization);GO:0007266(Rho protein signal transduction);GO:0007411(axon guidance);GO:0007596(blood coagulation);GO:0009615(response to virus);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016363(nuclear matrix);GO:0022604(regulation of cell morphogenesis);GO:0030010(establishment of cell polarity);GO:0030036(actin cytoskeleton organization);GO:0030042(actin filament depolymerization);GO:0030168(platelet activation);GO:0030836(positive regulation of actin filament depolymerization);GO:0030864(cortical actin cytoskeleton);GO:0031258(lamellipodium membrane);GO:0031982(vesicle);GO:0032587(ruffle membrane);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0043066(negative regulation of apoptotic process);GO:0043200(response to amino acid);GO:0045087(innate immune response);GO:0048013(ephrin receptor signaling pathway);GO:0061001(regulation of dendritic spine morphogenesis);GO:0070062(extracellular exosome)	04360(Axon guidance);04666(Fc gamma R-mediated phagocytosis);04810(Regulation of actin cytoskeleton)	NA	NA	cofilin 1 (non-muscle) [Source:HGNC Symbol;Acc:HGNC:1874]	86.28	78.76	75.85	222.77	268.82	223.52	0.36	-1.49	0	0.15	down	yes
MSTRG.4732	CNIH2	ENST00000528852;ENST00000311445;MSTRG.4732.3;ENST00000528063;ENST00000530519;MSTRG.4732.7;ENST00000531936	"GO:0005515(protein binding);GO:0005622(intracellular);GO:0005789(endoplasmic reticulum membrane);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0030054(cell junction);GO:0030425(dendrite);GO:0032281(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex);GO:0035249(synaptic transmission, glutamatergic);GO:0035556(intracellular signal transduction);GO:0042391(regulation of membrane potential);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045211(postsynaptic membrane);GO:0051668(localization within membrane);GO:2000311(regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity)"	NA	NA	NA	cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744]	0.67	0.55	0.24	5.87	5.07	8.1	0.22	-2.16	0	0.19	down	yes
MSTRG.4733	YIF1A	ENST00000496746;ENST00000485820;ENST00000526497;ENST00000471387;ENST00000359461;ENST00000376901;ENST00000494836;ENST00000484814;ENST00000431556;ENST00000528575;ENST00000376899;ENST00000616458;ENST00000534374	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005815(microtubule organizing center);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response);GO:0043231(intracellular membrane-bounded organelle);GO:0044267(cellular protein metabolic process)	NA	NA	NA	Yip1 interacting factor homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:16688]	30.47	30.1	49.77	13.14	12.07	17.24	2.56	1.35	0.04	0.32	up	yes
MSTRG.4760	LRFN4	ENST00000531590;ENST00000393952;ENST00000309602	GO:0005515(protein binding);GO:0016021(integral component of membrane)	NA	NA	NA	leucine rich repeat and fibronectin type III domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28456]	17.87	12.27	14.91	4.44	7.68	4.01	2.9	1.54	0.03	0.28	up	yes
MSTRG.477	MIR3917	ENST00000513116;ENST00000426559;MSTRG.477.3;MSTRG.477.4;ENST00000455785;ENST00000399728;ENST00000465604;ENST00000357865;ENST00000374291;ENST00000485226;ENST00000446334;ENST00000580971	NA	NA	NA	NA	NA	14.98	22	12.66	108.67	93.93	57.54	0.15	-2.69	0	0.18	down	yes
MSTRG.4801	C11orf24	ENST00000304271;MSTRG.4801.1;ENST00000531745;ENST00000533310;ENST00000530166;ENST00000527280;ENST00000529590;ENST00000532534;ENST00000532969;ENST00000529339	GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0016021(integral component of membrane)	NA	NA	NA	chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]	66.91	60.99	81.14	28.57	30.82	28.22	2.38	1.25	0.01	0.2	up	yes
MSTRG.484	EXTL1	MSTRG.484.1;MSTRG.484.2	NA	NA	NA	NA	NA	0.72	0.65	0.54	2.27	2.12	4.18	0.49	-1.02	0.04	0.32	down	yes
MSTRG.4840	CTTN	MSTRG.4840.1	NA	NA	NA	NA	NA	1.58	0.74	0.94	0	0.07	0.21	2.28	1.19	0	0.12	up	yes
MSTRG.4854	DHCR7	ENST00000534795;ENST00000407721;ENST00000355527;ENST00000533800;ENST00000525137;ENST00000527316;ENST00000534701;ENST00000526780;ENST00000525346;ENST00000531364;ENST00000529990;ENST00000527452	"GO:0001568(blood vessel development);GO:0005640(nuclear outer membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006695(cholesterol biosynthetic process);GO:0009791(post-embryonic development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016126(sterol biosynthetic process);GO:0016628(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0035264(multicellular organism growth);GO:0042127(regulation of cell proliferation);GO:0043231(intracellular membrane-bounded organelle);GO:0044281(small molecule metabolic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0047598(7-dehydrocholesterol reductase activity);GO:0055114(oxidation-reduction process)"	00100(Steroid biosynthesis);01100(Metabolic pathways)	NA	NA	7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860]	41.43	30.86	28.81	12.79	10.31	12.24	2.93	1.55	0.01	0.2	up	yes
MSTRG.4862	CLPB	MSTRG.4862.1	NA	NA	NA	NA	NA	0.4	0.81	1.53	3	3.43	2.37	0.41	-1.28	0.03	0.3	down	yes
MSTRG.4881	ANAPC15	ENST00000502597;ENST00000543050;ENST00000538117;ENST00000543587;ENST00000543015;MSTRG.4881.5;ENST00000545680;ENST00000227618;ENST00000542531;ENST00000535234;ENST00000545944;ENST00000538393;ENST00000535503;MSTRG.4881.14;ENST00000538919;ENST00000537644;ENST00000545333;ENST00000539395	GO:0005622(intracellular);GO:0005680(anaphase-promoting complex);GO:0007067(mitotic nuclear division);GO:0051301(cell division);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint)	NA	NA	NA	anaphase promoting complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:24531]	4.83	4.8	4.48	20.11	21.2	12.95	0.28	-1.84	0.01	0.2	down	yes
MSTRG.4904	RAB6A	ENST00000310653;ENST00000336083;ENST00000541973;ENST00000536566;ENST00000541588;ENST00000545625;ENST00000540771;ENST00000537446;ENST00000400470;ENST00000541795	"GO:0000042(protein targeting to Golgi);GO:0000139(Golgi membrane);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0018125(peptidyl-cysteine methylation);GO:0019882(antigen processing and presentation);GO:0019904(protein domain specific binding);GO:0031410(cytoplasmic vesicle);GO:0031489(myosin V binding);GO:0032482(Rab protein signal transduction);GO:0034067(protein localization to Golgi apparatus);GO:0034498(early endosome to Golgi transport);GO:0070062(extracellular exosome);GO:0070381(endosome to plasma membrane transport vesicle);GO:0072385(minus-end-directed organelle transport along microtubule)"	NA	NA	NA	"RAB6A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9786]"	25.76	30.57	28.68	8.2	7.1	10.83	3.04	1.6	0.01	0.21	up	yes
MSTRG.4948	ARRB1	ENST00000420843;ENST00000360025;ENST00000532447;ENST00000529741;ENST00000532525;ENST00000524400;ENST00000533609;ENST00000527385;ENST00000530086;ENST00000529280;ENST00000533255	GO:0000139(Golgi membrane);GO:0000187(activation of MAPK activity);GO:0000785(chromatin);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0002031(G-protein coupled receptor internalization);GO:0002092(positive regulation of receptor internalization);GO:0004857(enzyme inhibitor activity);GO:0005096(GTPase activator activity);GO:0005159(insulin-like growth factor receptor binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005834(heterotrimeric G-protein complex);GO:0005886(plasma membrane);GO:0005905(coated pit);GO:0006366(transcription from RNA polymerase II promoter);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0007165(signal transduction);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007219(Notch signaling pathway);GO:0007596(blood coagulation);GO:0007602(phototransduction);GO:0008134(transcription factor binding);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0014069(postsynaptic density);GO:0015031(protein transport);GO:0016323(basolateral plasma membrane);GO:0016567(protein ubiquitination);GO:0030168(platelet activation);GO:0030331(estrogen receptor binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031143(pseudopodium);GO:0031397(negative regulation of protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0031410(cytoplasmic vesicle);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0031625(ubiquitin protein ligase binding);GO:0031691(alpha-1A adrenergic receptor binding);GO:0031692(alpha-1B adrenergic receptor binding);GO:0031701(angiotensin receptor binding);GO:0031762(follicle-stimulating hormone receptor binding);GO:0031896(V2 vasopressin receptor binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032092(positive regulation of protein binding);GO:0032715(negative regulation of interleukin-6 production);GO:0032717(negative regulation of interleukin-8 production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034260(negative regulation of GTPase activity);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0035025(positive regulation of Rho protein signal transduction);GO:0035066(positive regulation of histone acetylation);GO:0035612(AP-2 adaptor complex binding);GO:0035615(clathrin adaptor activity);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0042699(follicle-stimulating hormone signaling pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043149(stress fiber assembly);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043197(dendritic spine);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043547(positive regulation of GTPase activity);GO:0044212(transcription regulatory region DNA binding);GO:0044325(ion channel binding);GO:0045211(postsynaptic membrane);GO:0045309(protein phosphorylated amino acid binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051219(phosphoprotein binding);GO:0061024(membrane organization);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0090240(positive regulation of histone H4 acetylation)	NA	NA	NA	"arrestin, beta 1 [Source:HGNC Symbol;Acc:HGNC:711]"	0.28	0.4	0.5	2	1.58	3.59	0.4	-1.33	0.04	0.33	down	yes
MSTRG.4974	RP11-111M22.2	MSTRG.4974.1	NA	NA	NA	NA	NA	0	0.16	0.5	1.68	0.87	1.5	0.47	-1.09	0.04	0.31	down	yes
MSTRG.5016	ALG8	ENST00000530608;ENST00000299626;ENST00000531213;ENST00000526849;ENST00000376156;ENST00000526737;ENST00000532306;ENST00000532552;ENST00000615266;ENST00000532440;ENST00000524925;ENST00000529139;ENST00000525755;ENST00000530454;ENST00000525870;ENST00000532050;ENST00000527099;ENST00000530910;ENST00000525761;ENST00000526928	"GO:0000033(alpha-1,3-mannosyltransferase activity);GO:0005789(endoplasmic reticulum membrane);GO:0006487(protein N-linked glycosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006490(oligosaccharide-lipid intermediate biosynthetic process);GO:0016021(integral component of membrane);GO:0016758(transferase activity, transferring hexosyl groups);GO:0018279(protein N-linked glycosylation via asparagine);GO:0042281(dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0097502(mannosylation)"	00510(N-Glycan biosynthesis);01100(Metabolic pathways)	NA	NA	"ALG8, alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23161]"	16.98	19.42	20.3	43.02	40.47	25.94	0.46	-1.12	0.02	0.26	down	yes
MSTRG.5018	KCTD21-AS1	MSTRG.5018.1;ENST00000532831;ENST00000523626;ENST00000530261;ENST00000500113;ENST00000527321;ENST00000600795	NA	NA	NA	NA	NA	0.15	0.44	0.39	1.98	2.71	0.78	0.4	-1.31	0.05	0.33	down	yes
MSTRG.5030	RP11-659G9.1	ENST00000532277;ENST00000524921;ENST00000528759;ENST00000525361;ENST00000533655;ENST00000532764;ENST00000532589;ENST00000525388;ENST00000329143;ENST00000533750;ENST00000474462	NA	NA	NA	NA	NA	0.22	0.77	0.24	4.67	3.65	0.73	0.26	-1.96	0.04	0.33	down	yes
MSTRG.5125	TAF1D	ENST00000624493;MSTRG.5125.2;ENST00000323981;ENST00000526015;ENST00000534079;MSTRG.5125.10;MSTRG.5125.6;MSTRG.5125.7;MSTRG.5125.8;MSTRG.5125.9;MSTRG.5125.11;MSTRG.5125.12;ENST00000546088;MSTRG.5125.13;ENST00000393259;ENST00000530769;ENST00000525928;ENST00000529435;ENST00000529900;ENST00000540232;ENST00000527169;ENST00000530089;ENST00000533794;ENST00000529794;ENST00000527068;ENST00000448108;ENST00000528734;ENST00000534770;ENST00000532235;ENST00000532455;ENST00000529508;ENST00000527690	"GO:0000183(chromatin silencing at rDNA);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005668(RNA polymerase transcription factor SL1 complex);GO:0005815(microtubule organizing center);GO:0006355(regulation of transcription, DNA-templated);GO:0006360(transcription from RNA polymerase I promoter);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0010467(gene expression);GO:0040029(regulation of gene expression, epigenetic);GO:0045814(negative regulation of gene expression, epigenetic)"	NA	NA	NA	"TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa [Source:HGNC Symbol;Acc:HGNC:28759]"	8.82	9.88	6.18	2.73	2.79	1.64	2.47	1.31	0.03	0.29	up	yes
MSTRG.5152	BIRC3	ENST00000526421;ENST00000263464;ENST00000528940;ENST00000527309;ENST00000527336	GO:0002224(toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007166(cell surface receptor signaling pathway);GO:0008270(zinc ion binding);GO:0010939(regulation of necrotic cell death);GO:0012501(programmed cell death);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0031398(positive regulation of protein ubiquitination);GO:0034121(regulation of toll-like receptor signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0039535(regulation of RIG-I signaling pathway);GO:0042981(regulation of apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045087(innate immune response);GO:0045088(regulation of innate immune response);GO:0050727(regulation of inflammatory response);GO:0060544(regulation of necroptotic process);GO:0060546(negative regulation of necroptotic process);GO:0070266(necroptotic process);GO:0070424(regulation of nucleotide-binding oligomerization domain containing signaling pathway);GO:0097300(programmed necrotic cell death);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:2000116(regulation of cysteine-type endopeptidase activity)	04120(Ubiquitin mediated proteolysis);04210(Apoptosis);04510(Focal adhesion);04621(NOD-like receptor signaling pathway);05145(Toxoplasmosis);05200(Pathways in cancer);05222(Small cell lung cancer)	NA	NA	baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591]	2.77	3.04	10.33	0.13	0.15	0.12	5.48	2.46	0.05	0.34	up	yes
MSTRG.5185	KDELC2	ENST00000323468;ENST00000530529;ENST00000530318;ENST00000524787	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005788(endoplasmic reticulum lumen);GO:0008150(biological_process)	NA	NA	NA	KDEL (Lys-Asp-Glu-Leu) containing 2 [Source:HGNC Symbol;Acc:HGNC:28496]	1.99	2.02	1.4	6.66	5.03	3.56	0.41	-1.3	0.02	0.27	down	yes
MSTRG.5255	ZPR1	ENST00000227322;MSTRG.5255.2;ENST00000429220;ENST00000444935;ENST00000449430;ENST00000425791;ENST00000498065;ENST00000487030	GO:0000226(microtubule cytoskeleton organization);GO:0001833(inner cell mass cell proliferation);GO:0001834(trophectodermal cell proliferation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0007165(signal transduction);GO:0008270(zinc ion binding);GO:0008283(cell proliferation);GO:0008380(RNA splicing);GO:0010628(positive regulation of gene expression);GO:0015030(Cajal body);GO:0021510(spinal cord development);GO:0030424(axon);GO:0030426(growth cone);GO:0030576(Cajal body organization);GO:0030971(receptor tyrosine kinase binding);GO:0031369(translation initiation factor binding);GO:0031641(regulation of myelination);GO:0032797(SMN complex);GO:0033120(positive regulation of RNA splicing);GO:0042023(DNA endoreduplication);GO:0042307(positive regulation of protein import into nucleus);GO:0043025(neuronal cell body);GO:0043204(perikaryon);GO:0045927(positive regulation of growth);GO:0048471(perinuclear region of cytoplasm);GO:0061564(axon development);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071931(positive regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0097504(Gemini of coiled bodies);GO:1902742(apoptotic process involved in development);GO:1990261(pre-mRNA catabolic process);GO:2000672(negative regulation of motor neuron apoptotic process)	NA	NA	NA	ZPR1 zinc finger [Source:HGNC Symbol;Acc:HGNC:13051]	18.08	24.6	27.39	6.22	9.2	9.08	2.62	1.39	0.03	0.28	up	yes
MSTRG.5298	RP11-110I1.12	MSTRG.5298.1;ENST00000582695;ENST00000526453	NA	NA	NA	NA	NA	0.13	0.08	0.09	1.88	1.62	0.7	0.42	-1.25	0.03	0.28	down	yes
MSTRG.5307	HYOU1	MSTRG.5307.1;ENST00000617285;ENST00000614711;ENST00000614668;ENST00000612687;MSTRG.5307.6;ENST00000532519;ENST00000621959;ENST00000527738;ENST00000531682;ENST00000543287;ENST00000530473;ENST00000531694;ENST00000534233;ENST00000526656;ENST00000531968;ENST00000532421;ENST00000533381;ENST00000527038;ENST00000622474;ENST00000529174;ENST00000530467;ENST00000610597;ENST00000526354	GO:0002931(response to ischemia);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0005790(smooth endoplasmic reticulum);GO:0005925(focal adhesion);GO:0006898(receptor-mediated endocytosis);GO:0016020(membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0034663(endoplasmic reticulum chaperone complex);GO:0034976(response to endoplasmic reticulum stress);GO:0036498(IRE1-mediated unfolded protein response);GO:0043066(negative regulation of apoptotic process);GO:0044267(cellular protein metabolic process);GO:0051087(chaperone binding);GO:0070062(extracellular exosome);GO:0071456(cellular response to hypoxia);GO:0071682(endocytic vesicle lumen);GO:1903298(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway);GO:1903382(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)	04141(Protein processing in endoplasmic reticulum)	NA	NA	hypoxia up-regulated 1 [Source:HGNC Symbol;Acc:HGNC:16931]	90.68	93.16	75.93	41.71	40.91	47.24	2.02	1.02	0.01	0.2	up	yes
MSTRG.5312	PHLDB1	ENST00000361417;MSTRG.5312.2;ENST00000530708;ENST00000530994;ENST00000528594;ENST00000621027;ENST00000356063;MSTRG.5312.9;ENST00000532639;ENST00000525427;ENST00000527259;ENST00000526374;MSTRG.5312.13;MSTRG.5312.15;ENST00000532517;ENST00000614369;MSTRG.5312.19;ENST00000527898;ENST00000534140;ENST00000612681;ENST00000526699;ENST00000527500;ENST00000528875;ENST00000392852;ENST00000526826;ENST00000529005;ENST00000525226;ENST00000526537;ENST00000620788	GO:0005515(protein binding);GO:0010470(regulation of gastrulation);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0045180(basal cortex);GO:0070507(regulation of microtubule cytoskeleton organization);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)	NA	NA	NA	"pleckstrin homology-like domain, family B, member 1 [Source:HGNC Symbol;Acc:HGNC:23697]"	0.61	0.62	0.62	2.25	2.72	3.91	0.46	-1.13	0.01	0.23	down	yes
MSTRG.5316	H2AFX	ENST00000530167;ENST00000375167	"GO:0000077(DNA damage checkpoint);GO:0000724(double-strand break repair via homologous recombination);GO:0000781(chromosome, telomeric region);GO:0000785(chromatin);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0000794(condensed nuclear chromosome);GO:0001673(male germ cell nucleus);GO:0001741(XY body);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005657(replication fork);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006334(nucleosome assembly);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0010212(response to ionizing radiation);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0021987(cerebral cortex development);GO:0035861(site of double-strand break);GO:0042393(histone binding);GO:0045739(positive regulation of DNA repair);GO:0046982(protein heterodimerization activity);GO:0051321(meiotic cell cycle);GO:0070062(extracellular exosome);GO:0071480(cellular response to gamma radiation);GO:0090398(cellular senescence)"	05322(Systemic lupus erythematosus)	NA	NA	"H2A histone family, member X [Source:HGNC Symbol;Acc:HGNC:4739]"	6.31	2.74	3.3	51.66	61.53	27.6	0.12	-3.07	0.02	0.25	down	yes
MSTRG.5319	C2CD2L	MSTRG.5319.1;ENST00000528271;MSTRG.5319.4;ENST00000529885;ENST00000336702;ENST00000529874;ENST00000525598;ENST00000528586	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0016021(integral component of membrane);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0043559(insulin binding)	NA	NA	NA	C2CD2-like [Source:HGNC Symbol;Acc:HGNC:29000]	3.78	3.75	3.67	1.3	1.19	1.38	2.09	1.07	0	0.1	up	yes
MSTRG.5324	MCAM	ENST00000264036;ENST00000528533;ENST00000525586;ENST00000524940;ENST00000528976;ENST00000529295;ENST00000530006;ENST00000528502;ENST00000526190;ENST00000525555;ENST00000534522;ENST00000530144;ENST00000526992	GO:0001525(angiogenesis);GO:0003094(glomerular filtration);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0007155(cell adhesion);GO:0009653(anatomical structure morphogenesis);GO:0009897(external side of plasma membrane);GO:0016021(integral component of membrane);GO:0030335(positive regulation of cell migration);GO:0061042(vascular wound healing)	NA	NA	NA	melanoma cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:6934]	7.25	8.65	10.06	15.53	23.04	15.44	0.49	-1.03	0.05	0.33	down	yes
MSTRG.5345	TBCEL	ENST00000529397;ENST00000284259;ENST00000528512;MSTRG.5345.3;ENST00000531148;ENST00000422003;ENST00000533712;ENST00000524726;ENST00000530362;ENST00000533134;ENST00000533169	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton)	NA	NA	NA	tubulin folding cofactor E-like [Source:HGNC Symbol;Acc:HGNC:28115]	0.44	1.49	0.96	2.75	1.99	1.44	0.47	-1.09	0	0.08	down	yes
MSTRG.5365	NRGN	ENST00000284292;MSTRG.5365.1;ENST00000412681	"GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0007399(nervous system development);GO:0008306(associative learning);GO:0012510(trans-Golgi network transport vesicle membrane);GO:0014069(postsynaptic density);GO:0021537(telencephalon development);GO:0030424(axon);GO:0030425(dendrite);GO:0031966(mitochondrial membrane);GO:0035556(intracellular signal transduction);GO:0043025(neuronal cell body);GO:0044327(dendritic spine head);GO:0045202(synapse);GO:0070300(phosphatidic acid binding);GO:1900273(positive regulation of long-term synaptic potentiation)"	NA	NA	NA	"neurogranin (protein kinase C substrate, RC3) [Source:HGNC Symbol;Acc:HGNC:8000]"	0.29	0.36	0.03	5.68	2.55	2.35	0.23	-2.11	0.01	0.24	down	yes
MSTRG.5390	HYLS1	ENST00000356438;ENST00000425380;MSTRG.5390.3;ENST00000526028	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005886(plasma membrane)	NA	NA	NA	hydrolethalus syndrome 1 [Source:HGNC Symbol;Acc:HGNC:26558]	0.24	0.47	0.03	6.36	6.62	2.49	0.17	-2.56	0.01	0.24	down	yes
MSTRG.5444	ADAMTS15	ENST00000299164	GO:0004222(metalloendopeptidase activity);GO:0005578(proteinaceous extracellular matrix);GO:0006508(proteolysis);GO:0008270(zinc ion binding);GO:0031012(extracellular matrix)	NA	NA	NA	"ADAM metallopeptidase with thrombospondin type 1 motif, 15 [Source:HGNC Symbol;Acc:HGNC:16305]"	0.62	0.39	0.65	4.49	3.92	1.98	0.33	-1.62	0.02	0.28	down	yes
MSTRG.5465	NCAPD3	MSTRG.5465.1;MSTRG.5465.2;ENST00000526787;ENST00000534532;ENST00000534548;ENST00000525964;ENST00000525432;ENST00000527944;ENST00000530396;ENST00000534290;ENST00000533155;ENST00000528065;ENST00000525485;ENST00000534227;ENST00000526422;ENST00000532445	GO:0000278(mitotic cell cycle);GO:0000793(condensed chromosome);GO:0000799(nuclear condensin complex);GO:0005488(binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0007076(mitotic chromosome condensation);GO:0016020(membrane);GO:0031618(nuclear pericentric heterochromatin);GO:0035064(methylated histone binding);GO:0042585(germinal vesicle);GO:0051301(cell division)	NA	NA	NA	"non-SMC condensin II complex, subunit D3 [Source:HGNC Symbol;Acc:HGNC:28952]"	1.69	2.03	1.84	12.79	12.27	6.99	0.21	-2.24	0	0.18	down	yes
MSTRG.550	DNAJC8	ENST00000603289;ENST00000263697;ENST00000489277;MSTRG.550.4;ENST00000470967;ENST00000482674;ENST00000488868	"GO:0000398(mRNA splicing, via spliceosome);GO:0005654(nucleoplasm);GO:0008380(RNA splicing);GO:0010467(gene expression)"	NA	NA	NA	"DnaJ (Hsp40) homolog, subfamily C, member 8 [Source:HGNC Symbol;Acc:HGNC:15470]"	19.45	39.9	23.82	45.98	47.06	42.6	0.46	-1.11	0.02	0.28	down	yes
MSTRG.5526	RAD51AP1	ENST00000536346;ENST00000536886;ENST00000544110;ENST00000535558;ENST00000442992;ENST00000228843;ENST00000352618;ENST00000538817;ENST00000544927;ENST00000536117;ENST00000544173;ENST00000544029;ENST00000544931	GO:0000724(double-strand break repair via homologous recombination);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006281(DNA repair);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0071479(cellular response to ionizing radiation)	NA	NA	NA	RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956]	0.72	1.42	0.57	8.14	10.07	3.17	0.19	-2.41	0.02	0.27	down	yes
MSTRG.553	SESN2	MSTRG.553.1;ENST00000253063	GO:0001932(regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006635(fatty acid beta-oxidation);GO:0006914(autophagy);GO:0007005(mitochondrion organization);GO:0009749(response to glucose);GO:0010467(gene expression);GO:0032042(mitochondrial DNA metabolic process);GO:0032868(response to insulin);GO:0042593(glucose homeostasis);GO:0043491(protein kinase B signaling);GO:0046323(glucose import);GO:0070328(triglyceride homeostasis);GO:0090526(regulation of gluconeogenesis involved in cellular glucose homeostasis);GO:1901031(regulation of response to reactive oxygen species);GO:2000479(regulation of cAMP-dependent protein kinase activity)	04115(p53 signaling pathway)	NA	NA	sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746]	43.45	27.35	32.65	3.71	4.48	3.51	8.33	3.06	0	0.12	up	yes
MSTRG.5547	NCAPD2	MSTRG.5547.1;ENST00000315579;ENST00000539714;ENST00000536538;ENST00000382457;ENST00000539084;ENST00000545732;ENST00000536090;ENST00000542472;ENST00000538600;ENST00000542492;ENST00000535804;ENST00000539885	GO:0000228(nuclear chromosome);GO:0000278(mitotic cell cycle);GO:0000793(condensed chromosome);GO:0000796(condensin complex);GO:0000797(condensin core heterodimer);GO:0005488(binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007067(mitotic nuclear division);GO:0007076(mitotic chromosome condensation);GO:0016020(membrane);GO:0030261(chromosome condensation);GO:0042393(histone binding);GO:0051301(cell division)	NA	NA	NA	"non-SMC condensin I complex, subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305]"	7.02	7.59	6.76	62.6	59.17	46.96	0.13	-2.94	0	0.1	down	yes
MSTRG.5565	CDCA3	MSTRG.5565.1;ENST00000422785;ENST00000604599;ENST00000603043;ENST00000538862;ENST00000229265;ENST00000535406;ENST00000536241;ENST00000544610;ENST00000540683;ENST00000545368;ENST00000535871;ENST00000446553	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0007067(mitotic nuclear division);GO:0008150(biological_process);GO:0016567(protein ubiquitination);GO:0051301(cell division)	NA	NA	NA	cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624]	0.77	0.44	0.32	11.37	14.18	3.75	0.14	-2.88	0.03	0.29	down	yes
MSTRG.5566	USP5	ENST00000229268;ENST00000389231;ENST00000542087;ENST00000535080;ENST00000537267;ENST00000541969;ENST00000542371	GO:0004197(cysteine-type endopeptidase activity);GO:0004843(ubiquitin-specific protease activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008242(omega peptidase activity);GO:0008270(zinc ion binding);GO:0016579(protein deubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0036459(ubiquitinyl hydrolase activity);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0071108(protein K48-linked deubiquitination)	NA	NA	NA	ubiquitin specific peptidase 5 (isopeptidase T) [Source:HGNC Symbol;Acc:HGNC:12628]	16.72	17.42	19.98	36.76	41.71	33.95	0.48	-1.06	0.01	0.2	down	yes
MSTRG.5577	LPCAT3	ENST00000535479;ENST00000261407;ENST00000535021;ENST00000540090;ENST00000543794;ENST00000537179;ENST00000538987;ENST00000540060;ENST00000620843;ENST00000536971;ENST00000545459;ENST00000538910	"GO:0005789(endoplasmic reticulum membrane);GO:0006644(phospholipid metabolic process);GO:0008152(metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0044281(small molecule metabolic process);GO:0046474(glycerophospholipid biosynthetic process);GO:0047184(1-acylglycerophosphocholine O-acyltransferase activity);GO:0097006(regulation of plasma lipoprotein particle levels)"	00564(Glycerophospholipid metabolism)	NA	NA	lysophosphatidylcholine acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30244]	3.52	3.41	2.85	8.79	7.34	8.69	0.46	-1.12	0	0.19	down	yes
MSTRG.5593	SLC2A3	ENST00000075120;ENST00000486749;ENST00000469295;ENST00000479059;ENST00000490763;ENST00000495813;ENST00000544291;ENST00000544936;ENST00000476634;ENST00000541671	GO:0005215(transporter activity);GO:0005351(sugar:proton symporter activity);GO:0005355(glucose transmembrane transporter activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006766(vitamin metabolic process);GO:0006767(water-soluble vitamin metabolic process);GO:0008645(hexose transport);GO:0015758(glucose transport);GO:0015992(proton transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019852(L-ascorbic acid metabolic process);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0035428(hexose transmembrane transport);GO:0044281(small molecule metabolic process);GO:0046323(glucose import);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome)	NA	NA	NA	"solute carrier family 2 (facilitated glucose transporter), member 3 [Source:HGNC Symbol;Acc:HGNC:11007]"	42.8	55	52.73	4.15	3.34	5.06	9.35	3.23	0	0.13	up	yes
MSTRG.5596	FOXJ2	ENST00000162391;ENST00000428177;ENST00000539192	"GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)"	NA	NA	NA	forkhead box J2 [Source:HGNC Symbol;Acc:HGNC:24818]	11.94	12.23	7.93	4.16	3.69	4.64	2.29	1.19	0.02	0.28	up	yes
MSTRG.5598	NECAP1	ENST00000339754;ENST00000546181;ENST00000542095;MSTRG.5598.3;MSTRG.5598.5;ENST00000545807;ENST00000450991;ENST00000544891;ENST00000541948;ENST00000540083;ENST00000537796	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005905(coated pit);GO:0006897(endocytosis);GO:0015031(protein transport);GO:0016020(membrane);GO:0030125(clathrin vesicle coat)	NA	NA	NA	NECAP endocytosis associated 1 [Source:HGNC Symbol;Acc:HGNC:24539]	11.58	5.35	11.56	2.59	6.91	6.25	2.6	1.38	0.04	0.31	up	yes
MSTRG.5606	PHC1	ENST00000538657;MSTRG.5606.2;ENST00000543824;MSTRG.5606.4;MSTRG.5606.5;ENST00000433083;ENST00000544916;ENST00000540574;ENST00000541181;ENST00000539928;ENST00000540809	GO:0001739(sex chromatin);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007275(multicellular organismal development);GO:0008270(zinc ion binding);GO:0016574(histone ubiquitination);GO:0016604(nuclear body);GO:0016925(protein sumoylation);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0071300(cellular response to retinoic acid)	NA	NA	NA	polyhomeotic homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:3182]	5.42	5.78	5.35	2.18	1.72	2.31	2.09	1.07	0	0.17	up	yes
MSTRG.5623	DDX12P	MSTRG.5623.1;MSTRG.5623.2;ENST00000432996	NA	NA	NA	NA	NA	0.85	0.74	0.73	3.21	2.33	1.33	0.49	-1.04	0.05	0.33	down	yes
MSTRG.5625	RP11-726G1.1	ENST00000518709;ENST00000520314;MSTRG.5625.3;MSTRG.5625.4;MSTRG.5625.5	NA	NA	NA	NA	NA	12.05	14.79	6.76	3.25	2.68	2.85	2.77	1.47	0.04	0.33	up	yes
MSTRG.5629	RP11-705C15.3	ENST00000633848;ENST00000611052;ENST00000576948;ENST00000573622;ENST00000575094;ENST00000545363;MSTRG.5629.8;ENST00000537616	NA	NA	NA	NA	NA	1.69	1.91	0.93	0.22	0.26	0.27	2.12	1.08	0.03	0.29	up	yes
MSTRG.5633	GABARAPL1	ENST00000539408;ENST00000542722;ENST00000545859;MSTRG.5633.4;MSTRG.5633.5;ENST00000266458;ENST00000421801;ENST00000544284;ENST00000545047;ENST00000541453;ENST00000629504;ENST00000543602;ENST00000540424;ENST00000537201;ENST00000545887;ENST00000541960;ENST00000546017;ENST00000535576;ENST00000545290	GO:0000045(autophagosome assembly);GO:0000407(pre-autophagosomal structure);GO:0000421(autophagosome membrane);GO:0000422(mitochondrion degradation);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0019898(extrinsic component of membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0030957(Tat protein binding);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm);GO:0044297(cell body);GO:0044804(nucleophagy);GO:0048487(beta-tubulin binding);GO:0050811(GABA receptor binding);GO:0061025(membrane fusion)	04140(Regulation of autophagy)	NA	NA	GABA(A) receptor-associated protein like 1 [Source:HGNC Symbol;Acc:HGNC:4068]	25.82	11.52	17.39	5.75	5.43	8.13	3.47	1.79	0	0.18	up	yes
MSTRG.5704	MGP	ENST00000539261;MSTRG.5704.1;ENST00000545199;ENST00000228938;MSTRG.5704.5;MSTRG.5704.6;ENST00000507170	GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0005201(extracellular matrix structural constituent);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0008147(structural constituent of bone);GO:0030154(cell differentiation);GO:0030500(regulation of bone mineralization);GO:0031012(extracellular matrix);GO:0070062(extracellular exosome)	NA	NA	NA	matrix Gla protein [Source:HGNC Symbol;Acc:HGNC:7060]	0.84	0.47	0.42	14.68	7.27	26.63	0.12	-3.03	0.02	0.27	down	yes
MSTRG.5743	GOLT1B	ENST00000535593;ENST00000545113;ENST00000540141;ENST00000229314;ENST00000545093;ENST00000539025;ENST00000631252;ENST00000542194	GO:0000139(Golgi membrane);GO:0004871(signal transducer activity);GO:0005783(endoplasmic reticulum);GO:0006629(lipid metabolic process);GO:0007165(signal transduction);GO:0015031(protein transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0016298(lipase activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0098588(bounding membrane of organelle)	NA	NA	NA	golgi transport 1B [Source:HGNC Symbol;Acc:HGNC:20175]	16.43	20.38	16.75	9.25	3.86	3.99	2.27	1.18	0.05	0.34	up	yes
MSTRG.5744	SPX	ENST00000256969;ENST00000535033;ENST00000544637;ENST00000535139;ENST00000543800;ENST00000537527	GO:0003084(positive regulation of systemic arterial blood pressure);GO:0005184(neuropeptide hormone activity);GO:0005615(extracellular space);GO:0010459(negative regulation of heart rate);GO:0030133(transport vesicle);GO:0031765(type 2 galanin receptor binding);GO:0031766(type 3 galanin receptor binding);GO:0032099(negative regulation of appetite);GO:0035814(negative regulation of renal sodium excretion);GO:0044539(long-chain fatty acid import);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051930(regulation of sensory perception of pain)	NA	NA	NA	spexin hormone [Source:HGNC Symbol;Acc:HGNC:28139]	1.41	2.56	2.23	0.08	0.11	0.03	2.44	1.29	0	0.17	up	yes
MSTRG.575	OPRD1	ENST00000234961;MSTRG.575.3	NA	NA	NA	NA	NA	2.88	2.01	1.54	7.83	10.36	5.63	0.37	-1.43	0.04	0.32	down	yes
MSTRG.5776	RP11-283G6.3	ENST00000242728;MSTRG.5776.1;MSTRG.5776.3;MSTRG.5776.4;ENST00000394326;ENST00000541271;ENST00000535914;ENST00000545819	NA	NA	NA	NA	NA	6.69	4.5	5.16	1.91	1.03	2.23	2.7	1.43	0.02	0.26	up	yes
MSTRG.580	EPB41	ENST00000343067;ENST00000356093;MSTRG.580.3;MSTRG.580.4;ENST00000482464;ENST00000349460;ENST00000373800;ENST00000347529;ENST00000373798;MSTRG.580.11;MSTRG.580.12;MSTRG.580.10;MSTRG.580.13;MSTRG.580.14;MSTRG.580.15;ENST00000373797;MSTRG.580.17;ENST00000488277;ENST00000490308;ENST00000460378;ENST00000462032	GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005545(1-phosphatidylinositol binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0008015(blood circulation);GO:0008091(spectrin);GO:0008092(cytoskeletal protein binding);GO:0014731(spectrin-associated cytoskeleton);GO:0016020(membrane);GO:0019898(extrinsic component of membrane);GO:0030036(actin cytoskeleton organization);GO:0030507(spectrin binding);GO:0030863(cortical cytoskeleton);GO:0030866(cortical actin cytoskeleton organization);GO:0032092(positive regulation of protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex)	04530(Tight junction)	NA	NA	erythrocyte membrane protein band 4.1 [Source:HGNC Symbol;Acc:HGNC:3377]	16.95	16.72	12.08	6.06	4.92	4.57	2.49	1.32	0.01	0.24	up	yes
MSTRG.5926	RP11-352M15.2	ENST00000609803	NA	NA	NA	NA	NA	2.49	2.39	1.69	0	0	0	3.23	1.69	0	0.16	up	yes
MSTRG.5932	SLC38A1	MSTRG.5932.1;MSTRG.5932.2;ENST00000398637;MSTRG.5932.4;MSTRG.5932.5;ENST00000549049;ENST00000439706;ENST00000546893;ENST00000552197;ENST00000612161;ENST00000548979;ENST00000549633;ENST00000551506;ENST00000550173	GO:0001504(neurotransmitter uptake);GO:0003333(amino acid transmembrane transport);GO:0005283(sodium:amino acid symporter activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0006865(amino acid transport);GO:0006868(glutamine transport);GO:0007268(synaptic transmission);GO:0015171(amino acid transmembrane transporter activity);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015186(L-glutamine transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030424(axon);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome)	04724(Glutamatergic synapse)	NA	NA	"solute carrier family 38, member 1 [Source:HGNC Symbol;Acc:HGNC:13447]"	8.21	10.75	6.54	1.43	1.93	1.13	3.45	1.78	0.01	0.22	up	yes
MSTRG.5954	SLC48A1	MSTRG.5954.1;ENST00000548498;ENST00000552003;ENST00000547002;MSTRG.5954.5;ENST00000549243;ENST00000442892;ENST00000442218;ENST00000551301;ENST00000461620;ENST00000476104	GO:0005515(protein binding);GO:0005765(lysosomal membrane);GO:0010008(endosome membrane);GO:0015232(heme transporter activity);GO:0015886(heme transport);GO:0016021(integral component of membrane)	NA	NA	NA	"solute carrier family 48 (heme transporter), member 1 [Source:HGNC Symbol;Acc:HGNC:26035]"	5.04	4.86	5.06	1.79	1.61	0.6	2.33	1.22	0.03	0.3	up	yes
MSTRG.5961	VDR	MSTRG.5961.1;ENST00000549336;ENST00000395324;ENST00000229022;ENST00000550325;ENST00000547065;ENST00000546653;ENST00000550314;ENST00000548664	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000902(cell morphogenesis);GO:0001501(skeletal system development);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007165(signal transduction);GO:0007275(multicellular organismal development);GO:0007595(lactation);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell proliferation);GO:0008434(calcitriol receptor activity);GO:0009887(organ morphogenesis);GO:0010467(gene expression);GO:0010628(positive regulation of gene expression);GO:0010839(negative regulation of keratinocyte proliferation);GO:0010980(positive regulation of vitamin D 24-hydroxylase activity);GO:0038183(bile acid signaling pathway);GO:0038186(lithocholic acid receptor activity);GO:0043235(receptor complex);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046697(decidualization);GO:0046965(retinoid X receptor binding);GO:0050892(intestinal absorption);GO:0060058(positive regulation of apoptotic process involved in mammary gland involution);GO:0060558(regulation of calcidiol 1-monooxygenase activity);GO:0060745(mammary gland branching involved in pregnancy);GO:0070561(vitamin D receptor signaling pathway);GO:0070644(vitamin D response element binding);GO:0090575(RNA polymerase II transcription factor complex);GO:1902098(calcitriol binding);GO:1902121(lithocholic acid binding)"	04961(Endocrine and other factor-regulated calcium reabsorption);04978(Mineral absorption);05152(Tuberculosis)	NA	NA	"vitamin D (1,25- dihydroxyvitamin D3) receptor [Source:HGNC Symbol;Acc:HGNC:12679]"	4.84	4.22	6.37	1.4	1.35	1.39	2.62	1.39	0.01	0.2	up	yes
MSTRG.5996	DDX23	ENST00000308025;ENST00000550834;ENST00000551331;ENST00000549795;ENST00000552802;ENST00000547290;ENST00000553065;ENST00000547135;ENST00000547165;ENST00000552069;ENST00000551189;ENST00000553182;ENST00000551098;ENST00000552512;ENST00000552369;ENST00000552555	"GO:0000354(cis assembly of pre-catalytic spliceosome);GO:0000375(RNA splicing, via transesterification reactions);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005682(U5 snRNP);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0010501(RNA secondary structure unwinding);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome);GO:0071013(catalytic step 2 spliceosome)"	03040(Spliceosome)	NA	NA	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Source:HGNC Symbol;Acc:HGNC:17347]	13.46	14.12	14.91	29.26	33.48	25.11	0.48	-1.06	0.01	0.21	down	yes
MSTRG.6009	RP11-386G11.10	MSTRG.6009.3;MSTRG.6009.2;MSTRG.6009.1;MSTRG.6009.4;MSTRG.6009.5;ENST00000548149;MSTRG.6009.7;MSTRG.6009.8;MSTRG.6009.6;ENST00000552893;ENST00000547387;ENST00000547712;ENST00000551496	NA	NA	NA	NA	NA	2.21	1.83	1.92	15.13	34.46	21.63	0.15	-2.74	0.01	0.21	down	yes
MSTRG.601	ZCCHC17	MSTRG.601.1;ENST00000546109;ENST00000615916;ENST00000616393;ENST00000616859;ENST00000618216;ENST00000344147;ENST00000479629;ENST00000373714;ENST00000422613;ENST00000627541	GO:0002230(positive regulation of defense response to virus by host);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0008270(zinc ion binding);GO:0022625(cytosolic large ribosomal subunit);GO:0030529(ribonucleoprotein complex);GO:0043231(intracellular membrane-bounded organelle);GO:0044822(poly(A) RNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)	NA	NA	NA	"zinc finger, CCHC domain containing 17 [Source:HGNC Symbol;Acc:HGNC:30246]"	13.22	17.58	19.64	29.5	37.16	34.74	0.48	-1.05	0.03	0.28	down	yes
MSTRG.6010	TUBA1B	ENST00000336023;ENST00000332858;ENST00000547765;ENST00000550367;ENST00000551324;ENST00000549870;ENST00000547476;ENST00000552984	GO:0000226(microtubule cytoskeleton organization);GO:0003725(double-stranded RNA binding);GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0006457(protein folding);GO:0007017(microtubule-based process);GO:0008152(metabolic process);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031625(ubiquitin protein ligase binding);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0044267(cellular protein metabolic process);GO:0051084('de novo' posttranslational protein folding);GO:0051258(protein polymerization);GO:0051301(cell division);GO:0070062(extracellular exosome);GO:0071353(cellular response to interleukin-4)	04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)	NA	NA	"tubulin, alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809]"	119.4	114.22	78.33	860.14	826.55	394.52	0.14	-2.89	0.01	0.24	down	yes
MSTRG.6012	TUBA1A	ENST00000301071;ENST00000295766;ENST00000550767;ENST00000547939;ENST00000546918;ENST00000552924;ENST00000548363;ENST00000550254;ENST00000550811	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0006457(protein folding);GO:0006996(organelle organization);GO:0007017(microtubule-based process);GO:0008152(metabolic process);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0044267(cellular protein metabolic process);GO:0051084('de novo' posttranslational protein folding);GO:0051258(protein polymerization);GO:0051301(cell division);GO:0055037(recycling endosome);GO:0070062(extracellular exosome)	04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)	NA	NA	"tubulin, alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]"	15.21	15.02	12.67	55.06	37.31	50.23	0.31	-1.69	0.01	0.2	down	yes
MSTRG.6013	TUBA1C	ENST00000549554;ENST00000550574;ENST00000541364;ENST00000549818;ENST00000552448;ENST00000552125;ENST00000301072;ENST00000549183;ENST00000548470	GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0006457(protein folding);GO:0007017(microtubule-based process);GO:0008152(metabolic process);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031982(vesicle);GO:0043234(protein complex);GO:0044267(cellular protein metabolic process);GO:0051084('de novo' posttranslational protein folding);GO:0051258(protein polymerization);GO:0051301(cell division)	04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)	NA	NA	"tubulin, alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768]"	54.45	56.99	47.46	287.81	368.05	134.14	0.19	-2.43	0.03	0.28	down	yes
MSTRG.6019	PRPH	ENST00000551194;ENST00000257860;ENST00000537252;ENST00000532332;ENST00000530631	GO:0001750(photoreceptor outer segment);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005883(neurofilament);GO:0016020(membrane);GO:0030424(axon);GO:0042622(photoreceptor outer segment membrane);GO:0044299(C-fiber);GO:0045098(type III intermediate filament);GO:0045104(intermediate filament cytoskeleton organization);GO:0046982(protein heterodimerization activity);GO:0070062(extracellular exosome)	NA	NA	NA	peripherin [Source:HGNC Symbol;Acc:HGNC:9461]	1.73	1.05	1.11	0.02	0.03	0.08	2.56	1.36	0	0.14	up	yes
MSTRG.6020	TROAP	MSTRG.6020.1;MSTRG.6020.2;ENST00000549275;ENST00000551245;MSTRG.6020.5;ENST00000380327;ENST00000548311;ENST00000550346;ENST00000550709;ENST00000546735;ENST00000549534;ENST00000546776;ENST00000257909;ENST00000551192;ENST00000547807;ENST00000551567;ENST00000548817;ENST00000547923	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007155(cell adhesion)	NA	NA	NA	trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327]	3.52	2.55	0.93	18.84	20.73	9.7	0.18	-2.45	0.04	0.32	down	yes
MSTRG.6021	TROAP	MSTRG.6021.1	NA	NA	NA	NA	NA	0.04	0	0	1.62	1.31	0.83	0.42	-1.24	0.01	0.21	down	yes
MSTRG.6028	MCRS1	ENST00000551598;MSTRG.6028.1;ENST00000546244;ENST00000548602;ENST00000551625;ENST00000343810;ENST00000550165;ENST00000552596;ENST00000548646;ENST00000547182;ENST00000357123;ENST00000549000;ENST00000553173;ENST00000548334;ENST00000548596;ENST00000549528;ENST00000552206	"GO:0000123(histone acetyltransferase complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006325(chromatin organization);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006464(cellular protein modification process);GO:0015629(actin cytoskeleton);GO:0030054(cell junction);GO:0031011(Ino80 complex);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0071339(MLL1 complex)"	NA	NA	NA	microspherule protein 1 [Source:HGNC Symbol;Acc:HGNC:6960]	13.2	12.1	15.16	26.55	34.62	25.44	0.5	-1	0.02	0.27	down	yes
MSTRG.604	SERINC2	ENST00000536859;MSTRG.604.3;ENST00000373709;ENST00000491976;ENST00000536384;MSTRG.604.8;MSTRG.604.9	NA	NA	NA	NA	NA	6.31	5.17	4.42	1.83	1.44	2.61	2.43	1.28	0.02	0.25	up	yes
MSTRG.6045	RACGAP1	ENST00000548961;MSTRG.6045.4;MSTRG.6045.5;MSTRG.6045.2;MSTRG.6045.3;ENST00000427314;ENST00000312377;ENST00000454520;ENST00000551016;ENST00000547905;ENST00000549342;ENST00000547061;ENST00000548320;ENST00000548598;ENST00000552310;ENST00000548158;ENST00000550149;ENST00000546786;ENST00000546595;ENST00000551145;ENST00000548824;ENST00000551260;ENST00000548644;ENST00000546723;ENST00000552921;ENST00000552157;ENST00000548247;ENST00000546764;ENST00000551876;ENST00000549777;ENST00000550651;ENST00000552004	"GO:0000281(mitotic cytokinesis);GO:0000915(actomyosin contractile ring assembly);GO:0001669(acrosomal vesicle);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007283(spermatogenesis);GO:0007405(neuroblast proliferation);GO:0007596(blood coagulation);GO:0008017(microtubule binding);GO:0008272(sulfate transport);GO:0009790(embryo development);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019901(protein kinase binding);GO:0030496(midbody);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0032154(cleavage furrow);GO:0032467(positive regulation of cytokinesis);GO:0035556(intracellular signal transduction);GO:0043014(alpha-tubulin binding);GO:0043015(gamma-tubulin binding);GO:0043547(positive regulation of GTPase activity);GO:0046872(metal ion binding);GO:0048487(beta-tubulin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051233(spindle midzone);GO:0051256(mitotic spindle midzone assembly);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0070062(extracellular exosome);GO:0072686(mitotic spindle);GO:0090307(mitotic spindle assembly);GO:0097149(centralspindlin complex)"	NA	NA	NA	Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]	12.1	14.17	6.94	56.47	64.02	22.82	0.21	-2.27	0.05	0.34	down	yes
MSTRG.6065	LETMD1	ENST00000551477;ENST00000547318;ENST00000552430;ENST00000553175;ENST00000550755;ENST00000550446;ENST00000550929;ENST00000262055;ENST00000547029;ENST00000550442;ENST00000549340;ENST00000548390;ENST00000546992;ENST00000551261;ENST00000548209;ENST00000548251;ENST00000550715;ENST00000550814;ENST00000547660;ENST00000547555;ENST00000548401;ENST00000549686;ENST00000418425;ENST00000547008;ENST00000547877;ENST00000550100;ENST00000380135;ENST00000552739;ENST00000548516;ENST00000552645;ENST00000547256;ENST00000552433;ENST00000546814;ENST00000551931;ENST00000550274;ENST00000553043;ENST00000549395;ENST00000623495	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0016021(integral component of membrane)	NA	NA	NA	LETM1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24241]	13.26	12.77	8.26	4.16	4.48	6.09	2.32	1.21	0.03	0.3	up	yes
MSTRG.6087	NR4A1	ENST00000360284;ENST00000546842;MSTRG.6087.3;ENST00000553200;ENST00000545748;ENST00000550082;ENST00000549102;ENST00000478250;ENST00000547206;ENST00000243050;ENST00000394825;ENST00000394824;ENST00000548232;ENST00000562373;ENST00000548733;ENST00000550557;ENST00000550339;ENST00000550582;ENST00000565848	"GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001938(positive regulation of endothelial cell proliferation);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003707(steroid hormone receptor activity);GO:0004879(ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008270(zinc ion binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010467(gene expression);GO:0030522(intracellular receptor signaling pathway);GO:0031965(nuclear membrane);GO:0035767(endothelial cell chemotaxis);GO:0035914(skeletal muscle cell differentiation);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043401(steroid hormone mediated signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045087(innate immune response);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0071310(cellular response to organic substance)"	04010(MAPK signaling pathway)	NA	NA	"nuclear receptor subfamily 4, group A, member 1 [Source:HGNC Symbol;Acc:HGNC:7980]"	19.04	24.38	13.55	2.88	3.67	8.37	4.09	2.03	0.05	0.33	up	yes
MSTRG.6089	ATG101	ENST00000547409;MSTRG.6089.2;ENST00000336854;ENST00000552544;ENST00000550604;ENST00000553049;ENST00000552947;ENST00000548915	GO:0000045(autophagosome assembly);GO:0000407(pre-autophagosomal structure);GO:0005515(protein binding);GO:0032403(protein complex binding);GO:0042802(identical protein binding)	NA	NA	NA	autophagy related 101 [Source:HGNC Symbol;Acc:HGNC:25679]	77.51	51.89	49.38	16.92	19.73	24.88	3.54	1.82	0	0.15	up	yes
MSTRG.6099	KRT7	ENST00000331817;MSTRG.6099.4;ENST00000549127;ENST00000552322;ENST00000548657;ENST00000550153;ENST00000549638	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005882(intermediate filament);GO:0016032(viral process);GO:0045095(keratin filament);GO:0070062(extracellular exosome)	NA	NA	NA	"keratin 7, type II [Source:HGNC Symbol;Acc:HGNC:6445]"	5.17	7.25	13.28	0.44	0.36	0.75	6.49	2.7	0.02	0.25	up	yes
MSTRG.61	HES4	ENST00000428771;ENST00000304952;ENST00000481869;ENST00000484667	"GO:0003677(DNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007399(nervous system development);GO:0008134(transcription factor binding);GO:0030154(cell differentiation);GO:0046983(protein dimerization activity)"	NA	NA	NA	hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149]	3.13	1.38	1.89	0.45	0.63	0.58	2.45	1.29	0	0.18	up	yes
MSTRG.6102	KRT86	ENST00000553310;ENST00000423955;ENST00000293525	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0070062(extracellular exosome)	NA	NA	NA	"keratin 86, type II [Source:HGNC Symbol;Acc:HGNC:6463]"	4.51	7.04	8.95	0.26	0.21	0.13	5.36	2.42	0	0.17	up	yes
MSTRG.6105	KRT81	ENST00000327741	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005882(intermediate filament);GO:0045095(keratin filament)	NA	NA	NA	"keratin 81, type II [Source:HGNC Symbol;Acc:HGNC:6458]"	9.94	15.36	26.73	0.63	0.97	0.29	8.62	3.11	0.01	0.23	up	yes
MSTRG.6107	KRT8	ENST00000552551;MSTRG.6107.2;ENST00000293308;ENST00000546583;ENST00000550170;ENST00000546897;ENST00000552150;ENST00000547031;ENST00000549176;ENST00000546826;ENST00000547176;ENST00000548998;ENST00000546900;ENST00000547413;ENST00000546542;ENST00000549198;ENST00000552877;ENST00000551318;ENST00000546921	GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005882(intermediate filament);GO:0005911(cell-cell junction);GO:0016010(dystrophin-associated glycoprotein complex);GO:0016032(viral process);GO:0016363(nuclear matrix);GO:0030018(Z disc);GO:0032403(protein complex binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0045095(keratin filament);GO:0045111(intermediate filament cytoskeleton);GO:0045214(sarcomere organization);GO:0051599(response to hydrostatic pressure);GO:0051707(response to other organism);GO:0060706(cell differentiation involved in embryonic placenta development);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0097110(scaffold protein binding);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097284(hepatocyte apoptotic process)	NA	NA	NA	"keratin 8, type II [Source:HGNC Symbol;Acc:HGNC:6446]"	6.63	7.56	7.45	2.22	2.43	4.53	2.28	1.19	0.04	0.32	up	yes
MSTRG.6117	SPRYD3	ENST00000301463;ENST00000547837;ENST00000537540;ENST00000550564;ENST00000550252	GO:0005515(protein binding)	NA	NA	NA	SPRY domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25920]	24.26	21.37	22.89	4.91	10.11	8.28	3.36	1.75	0.01	0.23	up	yes
MSTRG.6124	MFSD5	ENST00000546655;ENST00000534842;ENST00000551660;ENST00000329548;ENST00000552097	GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0015098(molybdate ion transmembrane transporter activity);GO:0015689(molybdate ion transport);GO:0016020(membrane);GO:0016021(integral component of membrane)	NA	NA	NA	major facilitator superfamily domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28156]	0.53	0.39	0.37	10.88	11.42	8.05	0.13	-2.98	0	0.13	down	yes
MSTRG.6126	ESPL1	ENST00000553219;ENST00000257934;ENST00000552671;ENST00000552462;MSTRG.6126.5;ENST00000550026;ENST00000535123;ENST00000553016;ENST00000549154;ENST00000552600	GO:0000070(mitotic sister chromatid segregation);GO:0000212(meiotic spindle organization);GO:0000278(mitotic cell cycle);GO:0000910(cytokinesis);GO:0003824(catalytic activity);GO:0004197(cysteine-type endopeptidase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007127(meiosis I);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0040001(establishment of mitotic spindle localization);GO:0045143(homologous chromosome segregation);GO:0045842(positive regulation of mitotic metaphase/anaphase transition);GO:0045875(negative regulation of sister chromatid cohesion);GO:0051307(meiotic chromosome separation);GO:0072686(mitotic spindle);GO:1901970(positive regulation of mitotic sister chromatid separation)	04110(Cell cycle);04114(Oocyte meiosis)	NA	NA	extra spindle pole bodies homolog 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:16856]	0.47	0.56	0.51	16.48	18.03	8.31	0.09	-3.5	0	0.17	down	yes
MSTRG.6130	AAAS	ENST00000209873;ENST00000552876;MSTRG.6130.2;ENST00000394384;ENST00000550286;ENST00000548931;ENST00000550033;ENST00000547520;ENST00000546572;ENST00000546393;ENST00000547761;ENST00000547757;ENST00000549983;ENST00000547238;ENST00000549821;ENST00000549450;ENST00000548258;ENST00000551724;ENST00000552161;ENST00000546562;ENST00000548880	GO:0000278(mitotic cell cycle);GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005975(carbohydrate metabolic process);GO:0006913(nucleocytoplasmic transport);GO:0007077(mitotic nuclear envelope disassembly);GO:0007612(learning);GO:0008645(hexose transport);GO:0009566(fertilization);GO:0010467(gene expression);GO:0010827(regulation of glucose transport);GO:0015031(protein transport);GO:0015758(glucose transport);GO:0016020(membrane);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019221(cytokine-mediated signaling pathway);GO:0031965(nuclear membrane);GO:0034605(cellular response to heat);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0046822(regulation of nucleocytoplasmic transport);GO:0051028(mRNA transport);GO:0055085(transmembrane transport);GO:1900034(regulation of cellular response to heat)	03013(RNA transport)	NA	NA	"achalasia, adrenocortical insufficiency, alacrimia [Source:HGNC Symbol;Acc:HGNC:13666]"	6.8	7.25	9.98	19.12	19.48	13.33	0.44	-1.18	0.03	0.28	down	yes
MSTRG.6137	ATF7	ENST00000448979;ENST00000267017;ENST00000591834;ENST00000548446;ENST00000420353;ENST00000456903;ENST00000551087;ENST00000546661;ENST00000588232;ENST00000588078;ENST00000548118;ENST00000591397;ENST00000550373;ENST00000589726	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0003676(nucleic acid binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0034399(nuclear periphery);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0051019(mitogen-activated protein kinase binding)"	NA	NA	NA	activating transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:792]	12.27	11.93	8.24	1.51	1.93	4.53	4.2	2.07	0.02	0.27	up	yes
MSTRG.6183	ZNF385A	MSTRG.6183.1;ENST00000551109;ENST00000352268;ENST00000550779;ENST00000546970;ENST00000552382;ENST00000551771;ENST00000549937;ENST00000551864	"GO:0000790(nuclear chromatin);GO:0002039(p53 binding);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007599(hemostasis);GO:0007611(learning or memory);GO:0007626(locomotory behavior);GO:0008270(zinc ion binding);GO:0008298(intracellular mRNA localization);GO:0010609(mRNA localization resulting in posttranscriptional regulation of gene expression);GO:0030220(platelet formation);GO:0030425(dendrite);GO:0035855(megakaryocyte development);GO:0043025(neuronal cell body);GO:0044822(poly(A) RNA binding);GO:0045600(positive regulation of fat cell differentiation);GO:0046872(metal ion binding);GO:0070889(platelet alpha granule organization);GO:1902164(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2000765(regulation of cytoplasmic translation)"	NA	NA	NA	zinc finger protein 385A [Source:HGNC Symbol;Acc:HGNC:17521]	24.71	19.71	15.01	6.64	6.84	9.91	2.8	1.49	0.01	0.24	up	yes
MSTRG.6193	GDF11	ENST00000257868;ENST00000546799	GO:0001501(skeletal system development);GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0005125(cytokine activity);GO:0005160(transforming growth factor beta receptor binding);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0007498(mesoderm development);GO:0008083(growth factor activity);GO:0008285(negative regulation of cell proliferation);GO:0009887(organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0021512(spinal cord anterior/posterior patterning);GO:0031016(pancreas development);GO:0040007(growth);GO:0042981(regulation of apoptotic process);GO:0043234(protein complex);GO:0043408(regulation of MAPK cascade);GO:0045596(negative regulation of cell differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0048468(cell development);GO:0048469(cell maturation);GO:0048593(camera-type eye morphogenesis);GO:0060021(palate development);GO:0060395(SMAD protein signal transduction)	NA	NA	NA	growth differentiation factor 11 [Source:HGNC Symbol;Acc:HGNC:4216]	4.32	3.96	2.56	11.61	10.4	15.52	0.37	-1.42	0.02	0.27	down	yes
MSTRG.62	ISG15	ENST00000624697;ENST00000379389	GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0016032(viral process);GO:0019221(cytokine-mediated signaling pathway);GO:0019941(modification-dependent protein catabolic process);GO:0019985(translesion synthesis);GO:0031386(protein tag);GO:0031397(negative regulation of protein ubiquitination);GO:0032020(ISG15-protein conjugation);GO:0032480(negative regulation of type I interferon production);GO:0032649(regulation of interferon-gamma production);GO:0034340(response to type I interferon);GO:0042742(defense response to bacterium);GO:0045071(negative regulation of viral genome replication);GO:0045087(innate immune response);GO:0045648(positive regulation of erythrocyte differentiation);GO:0051607(defense response to virus);GO:0060337(type I interferon signaling pathway)	04622(RIG-I-like receptor signaling pathway)	NA	NA	ISG15 ubiquitin-like modifier [Source:HGNC Symbol;Acc:HGNC:4053]	7.35	4.69	9.38	2.67	2.36	2.75	2.47	1.31	0.03	0.29	up	yes
MSTRG.6206	WIBG	ENST00000408946;ENST00000398213;ENST00000302533;ENST00000557259;ENST00000547925;ENST00000549939;ENST00000454792	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0035145(exon-exon junction complex);GO:0043022(ribosome binding);GO:0044822(poly(A) RNA binding);GO:0045727(positive regulation of translation);GO:1903259(exon-exon junction complex disassembly)"	03013(RNA transport);03015(mRNA surveillance pathway)	NA	NA	within bgcn homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:30258]	1.31	2.03	3.57	7.26	8.62	7.14	0.33	-1.6	0.03	0.28	down	yes
MSTRG.6210	CDK2	ENST00000266970;ENST00000556464;ENST00000555408;ENST00000553376;ENST00000440311;ENST00000555357;ENST00000354056;ENST00000554619;ENST00000556276;ENST00000556656;ENST00000556146	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0000781(chromosome, telomeric region);GO:0000793(condensed chromosome);GO:0000805(X chromosome);GO:0000806(Y chromosome);GO:0002088(lens development in camera-type eye);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005813(centrosome);GO:0005829(cytosol);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006468(protein phosphorylation);GO:0006813(potassium ion transport);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007067(mitotic nuclear division);GO:0007126(meiotic nuclear division);GO:0007265(Ras protein signal transduction);GO:0007596(blood coagulation);GO:0008284(positive regulation of cell proliferation);GO:0009636(response to toxic substance);GO:0015030(Cajal body);GO:0016301(kinase activity);GO:0016572(histone phosphorylation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018105(peptidyl-serine phosphorylation);GO:0030332(cyclin binding);GO:0031100(organ regeneration);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0032298(positive regulation of DNA-dependent DNA replication initiation);GO:0032355(response to estradiol);GO:0032403(protein complex binding);GO:0032869(cellular response to insulin stimulus);GO:0035173(histone kinase activity);GO:0042493(response to drug);GO:0043231(intracellular membrane-bounded organelle);GO:0045471(response to ethanol);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046686(response to cadmium ion);GO:0046872(metal ion binding);GO:0051298(centrosome duplication);GO:0051301(cell division);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051591(response to cAMP);GO:0051602(response to electrical stimulus);GO:0051726(regulation of cell cycle);GO:0060968(regulation of gene silencing);GO:0071732(cellular response to nitric oxide)"	04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04914(Progesterone-mediated oocyte maturation);05162(Measles);05200(Pathways in cancer);05215(Prostate cancer);05222(Small cell lung cancer)	NA	NA	cyclin-dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771]	7.38	8.38	6.3	16.71	17.57	12.57	0.46	-1.12	0.01	0.24	down	yes
MSTRG.6212	PA2G4	ENST00000549282;ENST00000267101;ENST00000411731;ENST00000550869;ENST00000551085;ENST00000546884;ENST00000551242;ENST00000549672;ENST00000415288;MSTRG.6212.11;ENST00000549472;ENST00000546748;ENST00000551176;ENST00000549205;ENST00000550828;ENST00000549644;ENST00000553131;ENST00000548709;ENST00000549832;ENST00000552691;ENST00000548861;ENST00000303305;ENST00000552766;ENST00000553057;ENST00000551061;ENST00000550166;ENST00000552528;ENST00000552266	"GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006364(rRNA processing);GO:0006417(regulation of translation);GO:0007050(cell cycle arrest);GO:0008152(metabolic process);GO:0008283(cell proliferation);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0030529(ribonucleoprotein complex);GO:0031625(ubiquitin protein ligase binding);GO:0043066(negative regulation of apoptotic process);GO:0044822(poly(A) RNA binding);GO:0045597(positive regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070062(extracellular exosome)"	NA	NA	NA	"proliferation-associated 2G4, 38kDa [Source:HGNC Symbol;Acc:HGNC:8550]"	33.36	35.85	26.08	69.05	61.04	74.05	0.47	-1.09	0.02	0.25	down	yes
MSTRG.6230	TIMELESS	ENST00000553532;ENST00000229201;ENST00000557589;ENST00000553314;ENST00000555808	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0002009(morphogenesis of an epithelium);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006974(cellular response to DNA damage stimulus);GO:0007067(mitotic nuclear division);GO:0007623(circadian rhythm);GO:0009582(detection of abiotic stimulus);GO:0009628(response to abiotic stimulus);GO:0015630(microtubule cytoskeleton);GO:0030324(lung development);GO:0042752(regulation of circadian rhythm);GO:0042803(protein homodimerization activity);GO:0044770(cell cycle phase transition);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0048754(branching morphogenesis of an epithelial tube);GO:0051301(cell division)"	NA	NA	NA	timeless circadian clock [Source:HGNC Symbol;Acc:HGNC:11813]	5.26	4.3	4.41	23.97	22.11	15.48	0.26	-1.97	0.01	0.2	down	yes
MSTRG.6239	SNORD59A	ENST00000384304	NA	NA	NA	NA	NA	3.15	1.33	0.87	0	0.09	0.93	2.97	1.57	0.03	0.29	up	yes
MSTRG.6248	NXPH4	ENST00000349394;ENST00000556415;ENST00000555154	GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005576(extracellular region);GO:0007218(neuropeptide signaling pathway)	NA	NA	NA	neurexophilin 4 [Source:HGNC Symbol;Acc:HGNC:8078]	2.98	1.54	2.05	0.52	0.86	0.97	2.21	1.15	0	0.08	up	yes
MSTRG.6256	NDUFA4L2	ENST00000554503;ENST00000393825;ENST00000555173;MSTRG.6256.4;ENST00000556732;ENST00000554688;ENST00000556234;ENST00000557276	NA	00190(Oxidative phosphorylation);01100(Metabolic pathways);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease)	NA	NA	"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 [Source:HGNC Symbol;Acc:HGNC:29836]"	2.98	2.1	2.28	0.13	0.18	0.16	3.26	1.71	0	0.1	up	yes
MSTRG.6263	DDIT3	ENST00000547303;ENST00000551116;ENST00000623876;MSTRG.6263.3;ENST00000346473;ENST00000618206;MSTRG.6263.7;ENST00000552740;ENST00000547526	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001955(blood vessel maturation);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005770(late endosome);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006915(apoptotic process);GO:0006974(cellular response to DNA damage stimulus);GO:0006983(ER overload response);GO:0006986(response to unfolded protein);GO:0007050(cell cycle arrest);GO:0008134(transcription factor binding);GO:0008140(cAMP response element binding protein binding);GO:0016055(Wnt signaling pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032757(positive regulation of interleukin-8 production);GO:0032792(negative regulation of CREB transcription factor activity);GO:0032993(protein-DNA complex);GO:0034976(response to endoplasmic reticulum stress);GO:0035976(AP1 complex);GO:0036488(CHOP-C/EBP complex);GO:0036499(PERK-mediated unfolded protein response);GO:0036500(ATF6-mediated unfolded protein response);GO:0042594(response to starvation);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043522(leucine zipper domain binding);GO:0043525(positive regulation of neuron apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0044212(transcription regulatory region DNA binding);GO:0044267(cellular protein metabolic process);GO:0044324(regulation of transcription involved in anterior/posterior axis specification);GO:0045454(cell redox homeostasis);GO:0045599(negative regulation of fat cell differentiation);GO:0045662(negative regulation of myoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051898(negative regulation of protein kinase B signaling);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1901216(positive regulation of neuron death);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:1990617(CHOP-ATF4 complex);GO:1990622(CHOP-ATF3 complex);GO:2000016(negative regulation of determination of dorsal identity)"	04010(MAPK signaling pathway);04141(Protein processing in endoplasmic reticulum)	NA	NA	DNA-damage-inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726]	218.6	209.41	185.47	11.92	16.17	12.79	14.84	3.89	0	0.1	up	yes
MSTRG.6273	B4GALNT1	MSTRG.6273.1;MSTRG.6273.5;MSTRG.6273.6;MSTRG.6273.7;MSTRG.6273.4;MSTRG.6273.2;MSTRG.6273.3;ENST00000553142;ENST00000341156;ENST00000552468;ENST00000418555;ENST00000552798;ENST00000547741;ENST00000549391;ENST00000449184;ENST00000550764;ENST00000552350;ENST00000548888;ENST00000552219;ENST00000548487;ENST00000551925;ENST00000550943;ENST00000551220	"GO:0001574(ganglioside biosynthetic process);GO:0003947((N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity);GO:0005886(plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0006687(glycosphingolipid metabolic process);GO:0007283(spermatogenesis);GO:0008152(metabolic process);GO:0008376(acetylgalactosaminyltransferase activity);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016758(transferase activity, transferring hexosyl groups);GO:0019915(lipid storage);GO:0030173(integral component of Golgi membrane);GO:0030259(lipid glycosylation)"	00604(Glycosphingolipid biosynthesis - ganglio series);01100(Metabolic pathways)	NA	NA	"beta-1,4-N-acetyl-galactosaminyl transferase 1 [Source:HGNC Symbol;Acc:HGNC:4117]"	4.98	3.98	4.58	13.8	12.07	8.93	0.43	-1.23	0.02	0.26	down	yes
MSTRG.6291	LRIG3	ENST00000379141;ENST00000320743;ENST00000550825;ENST00000552646;ENST00000547329;ENST00000550304;ENST00000552267;ENST00000548968	GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0016021(integral component of membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0032474(otolith morphogenesis)	NA	NA	NA	leucine-rich repeats and immunoglobulin-like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]	1.48	1.79	2.25	7.32	6.8	3.76	0.35	-1.52	0.02	0.25	down	yes
MSTRG.6340	XPOT	ENST00000332707;ENST00000540203;ENST00000400935;ENST00000542958;ENST00000538086;ENST00000541842	GO:0000049(tRNA binding);GO:0005488(binding);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006409(tRNA export from nucleus);GO:0006886(intracellular protein transport);GO:0008536(Ran GTPase binding)	NA	NA	NA	"exportin, tRNA [Source:HGNC Symbol;Acc:HGNC:12826]"	105.13	115.57	95.79	31.49	27.1	13.91	3.58	1.84	0.02	0.27	up	yes
MSTRG.6396	CPSF6	ENST00000435070;MSTRG.6396.3;MSTRG.6396.2;ENST00000550075;ENST00000456847;ENST00000266679;ENST00000550987;ENST00000551516;ENST00000547486	GO:0000166(nucleotide binding);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005849(mRNA cleavage factor complex);GO:0006378(mRNA polyadenylation);GO:0006397(mRNA processing);GO:0016020(membrane);GO:0030529(ribonucleoprotein complex);GO:0042382(paraspeckles);GO:0044822(poly(A) RNA binding);GO:0051262(protein tetramerization)	03015(mRNA surveillance pathway)	NA	NA	"cleavage and polyadenylation specific factor 6, 68kDa [Source:HGNC Symbol;Acc:HGNC:13871]"	4.7	6.21	8.72	16.23	14.56	8.83	0.42	-1.24	0.04	0.32	down	yes
MSTRG.6397	YEATS4	ENST00000247843;ENST00000548020;ENST00000549685;ENST00000552955	"GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007067(mitotic nuclear division);GO:0008022(protein C-terminus binding);GO:0016363(nuclear matrix);GO:0035267(NuA4 histone acetyltransferase complex);GO:0040008(regulation of growth);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	YEATS domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24859]	4.88	7.2	7.39	16.47	13.02	6.57	0.43	-1.21	0.04	0.32	down	yes
MSTRG.6414	TMEM19	ENST00000308086;ENST00000547843;ENST00000551238;ENST00000266673;ENST00000550524;ENST00000549735;ENST00000546677;ENST00000546795;ENST00000550787	GO:0005515(protein binding);GO:0016021(integral component of membrane)	NA	NA	NA	transmembrane protein 19 [Source:HGNC Symbol;Acc:HGNC:25605]	0.77	0.99	0.82	4.84	4.64	2.35	0.33	-1.62	0.01	0.23	down	yes
MSTRG.6415	RAB21	ENST00000261263;ENST00000358546;ENST00000547246;ENST00000552686	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005768(endosome);GO:0005769(early endosome);GO:0005789(endoplasmic reticulum membrane);GO:0005802(trans-Golgi network);GO:0005925(focal adhesion);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008089(anterograde axon cargo transport);GO:0008152(metabolic process);GO:0009898(cytoplasmic side of plasma membrane);GO:0012506(vesicle membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0017157(regulation of exocytosis);GO:0019003(GDP binding);GO:0030516(regulation of axon extension);GO:0030659(cytoplasmic vesicle membrane);GO:0032154(cleavage furrow);GO:0032482(Rab protein signal transduction);GO:0032580(Golgi cisterna membrane);GO:0043005(neuron projection);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050775(positive regulation of dendrite morphogenesis);GO:0070062(extracellular exosome);GO:0098559(cytoplasmic side of early endosome membrane);GO:2000643(positive regulation of early endosome to late endosome transport)	NA	NA	NA	"RAB21, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18263]"	3.74	4.11	3.57	0.94	1.1	2.05	2.26	1.18	0.02	0.27	up	yes
MSTRG.642	RBBP4	ENST00000414241;ENST00000373493;ENST00000527118;MSTRG.642.4;ENST00000401893;ENST00000524393;ENST00000526193;ENST00000492348;ENST00000525506;ENST00000465780;ENST00000373485;ENST00000477563;ENST00000458695;ENST00000490500;ENST00000445722;ENST00000475321;ENST00000531983;ENST00000463378;ENST00000460669;ENST00000482190	"GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006325(chromatin organization);GO:0006334(nucleosome assembly);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006338(chromatin remodeling);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008094(DNA-dependent ATPase activity);GO:0008285(negative regulation of cell proliferation);GO:0010467(gene expression);GO:0016580(Sin3 complex);GO:0016581(NuRD complex);GO:0016589(NURF complex);GO:0031492(nucleosomal DNA binding);GO:0031497(chromatin assembly);GO:0033186(CAF-1 complex);GO:0034080(CENP-A containing nucleosome assembly);GO:0035098(ESC/E(Z) complex);GO:0040029(regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0042826(histone deacetylase binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043234(protein complex);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051726(regulation of cell cycle);GO:0060416(response to growth hormone)"	NA	NA	NA	retinoblastoma binding protein 4 [Source:HGNC Symbol;Acc:HGNC:9887]	6.18	10.72	8.49	18.85	14.48	17.62	0.43	-1.23	0.01	0.21	down	yes
MSTRG.6435	BBS10	ENST00000393262;MSTRG.6435.2	NA	NA	NA	NA	NA	0.48	1.74	1.3	2.56	2.94	1.05	0.49	-1.03	0.05	0.34	down	yes
MSTRG.6439	CSRP2	MSTRG.6439.1;ENST00000311083;MSTRG.6439.2;ENST00000548783;ENST00000552330;ENST00000546966;ENST00000547435;ENST00000547557;ENST00000551725	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005925(focal adhesion);GO:0007275(multicellular organismal development);GO:0008270(zinc ion binding);GO:0030154(cell differentiation);GO:0045445(myoblast differentiation)	NA	NA	NA	cysteine and glycine-rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470]	4.64	4.97	3.66	13.61	14.12	8.8	0.38	-1.41	0.02	0.25	down	yes
MSTRG.6451	PAWR	ENST00000548075;ENST00000328827;ENST00000550603;ENST00000547699;ENST00000551712;ENST00000550006;ENST00000547571;ENST00000547016;ENST00000548426;ENST00000552637	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0003779(actin binding);GO:0005080(protein kinase C binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0006915(apoptotic process);GO:0008157(protein phosphatase 1 binding);GO:0008285(negative regulation of cell proliferation);GO:0009611(response to wounding);GO:0010040(response to iron(II) ion);GO:0015629(actin cytoskeleton);GO:0019899(enzyme binding);GO:0030424(axon);GO:0030889(negative regulation of B cell proliferation);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0042094(interleukin-2 biosynthetic process);GO:0042130(negative regulation of T cell proliferation);GO:0042986(positive regulation of amyloid precursor protein biosynthetic process);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043065(positive regulation of apoptotic process);GO:0043522(leucine zipper domain binding);GO:0043525(positive regulation of neuron apoptotic process);GO:0045760(positive regulation of action potential);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050966(detection of mechanical stimulus involved in sensory perception of pain);GO:0051017(actin filament bundle assembly);GO:0060450(positive regulation of hindgut contraction);GO:0071306(cellular response to vitamin E);GO:0071347(cellular response to interleukin-1);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0090281(negative regulation of calcium ion import);GO:0097190(apoptotic signaling pathway);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0098908(regulation of neuronal action potential);GO:1901082(positive regulation of relaxation of smooth muscle);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1990035(calcium ion import into cell);GO:2000391(positive regulation of neutrophil extravasation)"	NA	NA	NA	"PRKC, apoptosis, WT1, regulator [Source:HGNC Symbol;Acc:HGNC:8614]"	5.93	5.91	5.1	1.75	1.59	1.09	2.54	1.35	0	0.18	up	yes
MSTRG.646	YARS	ENST00000469100;ENST00000373477;ENST00000490826;ENST00000487404;ENST00000478828;ENST00000616261;ENST00000481895;ENST00000466052;ENST00000470377;ENST00000472692	GO:0000049(tRNA binding);GO:0000166(nucleotide binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004831(tyrosine-tRNA ligase activity);GO:0004871(signal transducer activity);GO:0005153(interleukin-8 receptor binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006418(tRNA aminoacylation for protein translation);GO:0006437(tyrosyl-tRNA aminoacylation);GO:0006915(apoptotic process);GO:0007165(signal transduction);GO:0010467(gene expression);GO:0044822(poly(A) RNA binding)	00970(Aminoacyl-tRNA biosynthesis)	NA	NA	tyrosyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12840]	82.22	64.03	64.17	26.02	23.85	26.2	2.92	1.55	0	0.14	up	yes
MSTRG.6515	SOCS2-AS1	ENST00000499137;ENST00000500986;MSTRG.6515.3;MSTRG.6515.4;ENST00000547845;ENST00000551626	NA	NA	NA	NA	NA	2.57	2.15	1.36	0.49	0.38	0.59	2.15	1.1	0.02	0.27	up	yes
MSTRG.6517	BTG1	ENST00000551843;ENST00000549802;ENST00000551563;ENST00000623676;ENST00000551764;ENST00000553207;ENST00000551306;ENST00000552277;ENST00000256015;ENST00000548552;ENST00000552315	"GO:0003712(transcription cofactor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006479(protein methylation);GO:0006979(response to oxidative stress);GO:0007283(spermatogenesis);GO:0008285(negative regulation of cell proliferation);GO:0016477(cell migration);GO:0019899(enzyme binding);GO:0019900(kinase binding);GO:0030308(negative regulation of cell growth);GO:0043434(response to peptide hormone);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045663(positive regulation of myoblast differentiation);GO:0045766(positive regulation of angiogenesis);GO:2000271(positive regulation of fibroblast apoptotic process)"	NA	NA	NA	"B-cell translocation gene 1, anti-proliferative [Source:HGNC Symbol;Acc:HGNC:1130]"	23.74	23.7	27.66	8.45	7.94	14.22	2.65	1.41	0.03	0.28	up	yes
MSTRG.652	RNF19B	MSTRG.652.1;ENST00000373456;ENST00000356990;MSTRG.652.4;ENST00000235150	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:0044194(cytolytic granule);GO:0072643(interferon-gamma secretion)	NA	NA	NA	ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886]	49.27	27.8	27.38	6.23	9.77	5.37	5.28	2.4	0.01	0.23	up	yes
MSTRG.6548	SNRPF	ENST00000266735;ENST00000551316;ENST00000553192;ENST00000552085;ENST00000549580	"GO:0000387(spliceosomal snRNP assembly);GO:0000398(mRNA splicing, via spliceosome);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0005683(U7 snRNP);GO:0005685(U1 snRNP);GO:0005687(U4 snRNP);GO:0005689(U12-type spliceosomal complex);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0008334(histone mRNA metabolic process);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0030532(small nuclear ribonucleoprotein complex);GO:0031124(mRNA 3'-end processing);GO:0034660(ncRNA metabolic process);GO:0034709(methylosome);GO:0034715(pICln-Sm protein complex);GO:0034719(SMN-Sm protein complex);GO:0071013(catalytic step 2 spliceosome);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)"	NA	NA	NA	small nuclear ribonucleoprotein polypeptide F [Source:HGNC Symbol;Acc:HGNC:11162]	6.71	5.61	5.56	14.91	17.54	13.3	0.45	-1.16	0.01	0.21	down	yes
MSTRG.6560	TMPO	ENST00000556029;ENST00000548911;ENST00000343315;ENST00000266732;ENST00000393053;ENST00000261210;ENST00000549938;ENST00000552831;ENST00000547214;ENST00000556678;ENST00000548223;ENST00000551987	"GO:0000785(chromatin);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005521(lamin binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005637(nuclear inner membrane);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane)"	NA	NA	NA	thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875]	1.55	4.89	2.53	19.57	18.54	6.55	0.15	-2.7	0.01	0.22	down	yes
MSTRG.6597	NUP37	ENST00000552283;ENST00000546385;ENST00000251074;ENST00000547269;ENST00000551744;ENST00000551200;ENST00000543021;ENST00000548994;ENST00000550459	GO:0000278(mitotic cell cycle);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005975(carbohydrate metabolic process);GO:0007059(chromosome segregation);GO:0007067(mitotic nuclear division);GO:0007077(mitotic nuclear envelope disassembly);GO:0007264(small GTPase mediated signal transduction);GO:0008645(hexose transport);GO:0010467(gene expression);GO:0010827(regulation of glucose transport);GO:0015031(protein transport);GO:0015758(glucose transport);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0019221(cytokine-mediated signaling pathway);GO:0031080(nuclear pore outer ring);GO:0034605(cellular response to heat);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0044281(small molecule metabolic process);GO:0051028(mRNA transport);GO:0051301(cell division);GO:0055085(transmembrane transport);GO:1900034(regulation of cellular response to heat)	03013(RNA transport)	NA	NA	nucleoporin 37kDa [Source:HGNC Symbol;Acc:HGNC:29929]	3.13	4.22	4.41	14.18	14.61	7.6	0.31	-1.69	0.01	0.24	down	yes
MSTRG.66	RP11-465B22.3	MSTRG.66.3;MSTRG.66.1;MSTRG.66.2;MSTRG.66.4;ENST00000427998;ENST00000394517;ENST00000412397;ENST00000433695;ENST00000451054	NA	NA	NA	NA	NA	2.09	3.11	2.79	0.03	0.13	0.03	3.11	1.63	0	0.14	up	yes
MSTRG.6621	C12orf73	ENST00000543740;ENST00000378090;ENST00000547975;ENST00000549478;ENST00000553183;ENST00000549960;ENST00000547945;ENST00000552460;ENST00000552940;ENST00000546819;ENST00000546540	GO:0005576(extracellular region)	NA	NA	NA	chromosome 12 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:34450]	5.47	5.81	5.08	1.7	1.77	1.96	2.31	1.21	0	0.13	up	yes
MSTRG.6639	ALDH1L2	MSTRG.6639.1;ENST00000258494;ENST00000552270;ENST00000548418;ENST00000552427	"GO:0003824(catalytic activity);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0008152(metabolic process);GO:0008168(methyltransferase activity);GO:0009058(biosynthetic process);GO:0009258(10-formyltetrahydrofolate catabolic process);GO:0016155(formyltetrahydrofolate dehydrogenase activity);GO:0016491(oxidoreductase activity);GO:0016742(hydroxymethyl-, formyl- and related transferase activity);GO:0032259(methylation);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome)"	00670(One carbon pool by folate)	NA	NA	"aldehyde dehydrogenase 1 family, member L2 [Source:HGNC Symbol;Acc:HGNC:26777]"	4.01	9.08	6.1	0.97	0.78	0.34	3.03	1.6	0	0.14	up	yes
MSTRG.6648	TCP11L2	ENST00000547153;ENST00000299045;ENST00000546625;ENST00000553098;ENST00000549906;ENST00000551802;ENST00000548428;ENST00000551228	NA	NA	NA	NA	"t-complex 11, testis-specific-like 2 [Source:HGNC Symbol;Acc:HGNC:28627]"	1.46	1.62	1.22	0.15	0.12	0.43	2.06	1.04	0.01	0.23	up	yes
MSTRG.6672	ISCU	MSTRG.6672.1;MSTRG.6672.2;MSTRG.6672.3;ENST00000545932;ENST00000552072;ENST00000535729;ENST00000431221;ENST00000547005;ENST00000311893;ENST00000392807;ENST00000539580;ENST00000539593;ENST00000535405;ENST00000544493;ENST00000540154;ENST00000538193	"GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006879(cellular iron ion homeostasis);GO:0008198(ferrous iron binding);GO:0009399(nitrogen fixation);GO:0016226(iron-sulfur cluster assembly);GO:0032947(protein complex scaffold);GO:0036455(iron-sulfur transferase activity);GO:0044281(small molecule metabolic process);GO:0044571([2Fe-2S] cluster assembly);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0097428(protein maturation by iron-sulfur cluster transfer)"	NA	NA	NA	iron-sulfur cluster assembly enzyme [Source:HGNC Symbol;Acc:HGNC:29882]	18.79	15.36	15.81	6.13	6.65	5.07	2.63	1.39	0	0.18	up	yes
MSTRG.6680	UNG	ENST00000242576;ENST00000540158;ENST00000336865;ENST00000539287;ENST00000446767	"GO:0004844(uracil DNA N-glycosylase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0006284(base-excision repair);GO:0006285(base-excision repair, AP site formation);GO:0016032(viral process);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0016447(somatic recombination of immunoglobulin gene segments);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0045008(depyrimidination)"	03410(Base excision repair);05340(Primary immunodeficiency)	NA	NA	uracil-DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572]	2.47	5.78	4.44	20.6	19.4	13.46	0.2	-2.35	0	0.12	down	yes
MSTRG.67	RP11-54O7.18	MSTRG.67.1;ENST00000442292	NA	NA	NA	NA	NA	1.93	1.05	1.83	0.11	0.15	0.24	2.54	1.35	0	0.17	up	yes
MSTRG.6717	PPTC7	ENST00000354300;MSTRG.6717.1;ENST00000548721	GO:0003824(catalytic activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005739(mitochondrion);GO:0016311(dephosphorylation);GO:0046872(metal ion binding)	NA	NA	NA	PTC7 protein phosphatase homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:30695]	27.21	22.05	19.2	4.83	4.85	2.2	4.64	2.21	0.02	0.25	up	yes
MSTRG.6737	MAPKAPK5-AS1	ENST00000428207;ENST00000443596;ENST00000456429;ENST00000442119;ENST00000590479;ENST00000609983	NA	NA	NA	NA	NA	14.33	12.98	12.13	5.54	3.58	6.35	2.44	1.29	0.02	0.27	up	yes
MSTRG.677	GJB3	ENST00000373366;ENST00000373362	GO:0001701(in utero embryonic development);GO:0001890(placenta development);GO:0005243(gap junction channel activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005911(cell-cell junction);GO:0005921(gap junction);GO:0005922(connexon complex);GO:0007154(cell communication);GO:0007605(sensory perception of sound);GO:0016021(integral component of membrane);GO:0043588(skin development);GO:0055085(transmembrane transport)	NA	NA	NA	"gap junction protein, beta 3, 31kDa [Source:HGNC Symbol;Acc:HGNC:4285]"	4.18	4.3	8.22	0.55	0.72	0.38	3.9	1.96	0.02	0.25	up	yes
MSTRG.6804	RFC5	ENST00000449641;MSTRG.6804.2;MSTRG.6804.3;ENST00000537315;ENST00000484086;ENST00000420967;MSTRG.6804.8;MSTRG.6804.7;ENST00000454402;MSTRG.6804.10;ENST00000392542;ENST00000535092;ENST00000472603;ENST00000543153	"GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003689(DNA clamp loader activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005663(DNA replication factor C complex);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019899(enzyme binding);GO:0019985(translesion synthesis);GO:0032201(telomere maintenance via semi-conservative replication);GO:0042276(error-prone translesion synthesis);GO:0042769(DNA damage response, detection of DNA damage);GO:0070987(error-free translesion synthesis)"	03030(DNA replication);03420(Nucleotide excision repair);03430(Mismatch repair)	NA	NA	"replication factor C (activator 1) 5, 36.5kDa [Source:HGNC Symbol;Acc:HGNC:9973]"	4.59	5.39	3.96	16.23	16	10.28	0.33	-1.61	0.01	0.22	down	yes
MSTRG.682	SFPQ	MSTRG.682.3;MSTRG.682.1;MSTRG.682.2;ENST00000471991;ENST00000468598;ENST00000460428;MSTRG.682.4;ENST00000466745;ENST00000466213;ENST00000490668;ENST00000485365;MSTRG.682.9;MSTRG.682.10;ENST00000485454;ENST00000357214	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000166(nucleotide binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0000724(double-strand break repair via homologous recombination);GO:0000785(chromatin);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006397(mRNA processing);GO:0006974(cellular response to DNA damage stimulus);GO:0008380(RNA splicing);GO:0016363(nuclear matrix);GO:0042382(paraspeckles);GO:0042752(regulation of circadian rhythm);GO:0042754(negative regulation of circadian rhythm);GO:0042826(histone deacetylase binding);GO:0044212(transcription regulatory region DNA binding);GO:0044822(poly(A) RNA binding);GO:0045876(positive regulation of sister chromatid cohesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0051276(chromosome organization);GO:0051726(regulation of cell cycle);GO:0070932(histone H3 deacetylation);GO:1902177(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)"	NA	NA	NA	splicing factor proline/glutamine-rich [Source:HGNC Symbol;Acc:HGNC:10774]	12.63	12.26	14.87	52.2	54.5	25.05	0.28	-1.81	0.03	0.29	down	yes
MSTRG.6828	CIT	ENST00000392521;ENST00000261833;ENST00000545913;MSTRG.6828.4;MSTRG.6828.5;MSTRG.6828.6;ENST00000392520;ENST00000544872;ENST00000469414;ENST00000538073;ENST00000543324;ENST00000544800;ENST00000543239;ENST00000536008;ENST00000408396;ENST00000544588;ENST00000541841;ENST00000488203	"GO:0000070(mitotic sister chromatid segregation);GO:0000910(cytokinesis);GO:0001726(ruffle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005773(vacuole);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007067(mitotic nuclear division);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:0007264(small GTPase mediated signal transduction);GO:0007283(spermatogenesis);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016358(dendrite development);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0017124(SH3 domain binding);GO:0030165(PDZ domain binding);GO:0032467(positive regulation of cytokinesis);GO:0035556(intracellular signal transduction);GO:0046872(metal ion binding);GO:0048699(generation of neurons);GO:0050774(negative regulation of dendrite morphogenesis);GO:0097110(scaffold protein binding)"	NA	NA	NA	citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]	1.47	1.23	0.89	9.25	7.18	6.02	0.25	-2.02	0	0.19	down	yes
MSTRG.6838	SRSF9	ENST00000229390;ENST00000548326;ENST00000548792;ENST00000603963;ENST00000550458;ENST00000546942	"GO:0000166(nucleotide binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006369(termination of RNA polymerase II transcription);GO:0006376(mRNA splice site selection);GO:0006397(mRNA processing);GO:0006406(mRNA export from nucleus);GO:0008380(RNA splicing);GO:0010467(gene expression);GO:0031124(mRNA 3'-end processing);GO:0044822(poly(A) RNA binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome)"	03040(Spliceosome)	NA	NA	serine/arginine-rich splicing factor 9 [Source:HGNC Symbol;Acc:HGNC:10791]	9.88	11.51	12.4	31.62	33.62	35.96	0.35	-1.54	0	0.15	down	yes
MSTRG.6853	MLEC	ENST00000228506;ENST00000412616;ENST00000545525;ENST00000535656;ENST00000535413	GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006457(protein folding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018279(protein N-linked glycosylation via asparagine);GO:0019899(enzyme binding);GO:0030246(carbohydrate binding);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process)	NA	NA	NA	malectin [Source:HGNC Symbol;Acc:HGNC:28973]	24.79	44.42	30.33	56.46	53.07	66.99	0.48	-1.06	0.04	0.32	down	yes
MSTRG.6862	C12orf43	ENST00000288757;MSTRG.6862.2;ENST00000445832;ENST00000502891;ENST00000537817;ENST00000546272;ENST00000539736;ENST00000538296;ENST00000535367;ENST00000508193	NA	NA	NA	NA	chromosome 12 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:25719]	1.18	0.85	1.93	4.74	5.93	3.74	0.4	-1.32	0.04	0.31	down	yes
MSTRG.6865	P2RX4	ENST00000337233;ENST00000359949;ENST00000543430;ENST00000540930;ENST00000543318;ENST00000499638;ENST00000543984;ENST00000538701;ENST00000542067;ENST00000541187;ENST00000538417;ENST00000314442;ENST00000397924	GO:0001614(purinergic nucleotide receptor activity);GO:0001894(tissue homeostasis);GO:0002028(regulation of sodium ion transport);GO:0004931(extracellular ATP-gated cation channel activity);GO:0005102(receptor binding);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005639(integral component of nuclear inner membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006809(nitric oxide biosynthetic process);GO:0006810(transport);GO:0006812(cation transport);GO:0006816(calcium ion transport);GO:0007165(signal transduction);GO:0008144(drug binding);GO:0008217(regulation of blood pressure);GO:0008270(zinc ion binding);GO:0010524(positive regulation of calcium ion transport into cytosol);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0019228(neuronal action potential);GO:0019233(sensory perception of pain);GO:0030054(cell junction);GO:0030424(axon);GO:0030425(dendrite);GO:0032308(positive regulation of prostaglandin secretion);GO:0033198(response to ATP);GO:0034220(ion transmembrane transport);GO:0034405(response to fluid shear stress);GO:0035590(purinergic nucleotide receptor signaling pathway);GO:0042118(endothelial cell activation);GO:0042311(vasodilation);GO:0042803(protein homodimerization activity);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043197(dendritic spine);GO:0045177(apical part of cell);GO:0045202(synapse);GO:0045296(cadherin binding);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048471(perinuclear region of cytoplasm);GO:0050850(positive regulation of calcium-mediated signaling);GO:0051260(protein homooligomerization);GO:0051899(membrane depolarization);GO:0051928(positive regulation of calcium ion transport);GO:0055117(regulation of cardiac muscle contraction);GO:0055119(relaxation of cardiac muscle);GO:0060079(regulation of excitatory postsynaptic membrane potential);GO:0070062(extracellular exosome);GO:0071318(cellular response to ATP);GO:0097190(apoptotic signaling pathway);GO:0098655(cation transmembrane transport)	04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction)	NA	NA	"purinergic receptor P2X, ligand gated ion channel, 4 [Source:HGNC Symbol;Acc:HGNC:8535]"	2.65	2.23	3.21	0.77	0.7	1.32	2.12	1.08	0.02	0.25	up	yes
MSTRG.6895	KNTC1	MSTRG.6895.1;ENST00000535410;ENST00000333479;ENST00000535186;ENST00000423927;ENST00000545065;ENST00000377192;ENST00000436959;ENST00000541466;ENST00000546125;ENST00000536625;ENST00000539013;ENST00000541427;ENST00000534995	GO:0000278(mitotic cell cycle);GO:0000777(condensed chromosome kinetochore);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005828(kinetochore microtubule);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006461(protein complex assembly);GO:0007067(mitotic nuclear division);GO:0007093(mitotic cell cycle checkpoint);GO:0007096(regulation of exit from mitosis);GO:0007264(small GTPase mediated signal transduction);GO:0015629(actin cytoskeleton);GO:0051301(cell division);GO:1990423(RZZ complex)	NA	NA	NA	kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255]	0.46	0.59	0.45	3.29	2.3	1.06	0.39	-1.34	0.03	0.29	down	yes
MSTRG.6912	C12orf65	ENST00000253233;ENST00000538888;ENST00000425637;ENST00000536130;ENST00000546132;ENST00000366329;ENST00000543139;ENST00000429587	GO:0003747(translation release factor activity);GO:0005739(mitochondrion);GO:0006415(translational termination)	NA	NA	NA	chromosome 12 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:26784]	0.55	0.65	0.71	4.39	3.47	1.71	0.33	-1.58	0.02	0.26	down	yes
MSTRG.6919	RILPL1	ENST00000376874;ENST00000340724;ENST00000544468;ENST00000623184;MSTRG.6919.5;MSTRG.6919.6	NA	NA	NA	NA	NA	2.54	2.06	2.26	0.55	0.81	1.41	2.03	1.02	0.01	0.22	up	yes
MSTRG.6929	TCTN2	ENST00000541523;ENST00000426174;ENST00000303372;ENST00000543998	GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0006996(organelle organization);GO:0007224(smoothened signaling pathway);GO:0016021(integral component of membrane);GO:0036038(TCTN-B9D complex);GO:0042384(cilium assembly);GO:0060170(ciliary membrane);GO:0060271(cilium morphogenesis)	NA	NA	NA	tectonic family member 2 [Source:HGNC Symbol;Acc:HGNC:25774]	0.96	1.24	1.13	4.11	3.47	3.36	0.42	-1.27	0	0.08	down	yes
MSTRG.6960	UBC	MSTRG.6960.5;MSTRG.6960.1;MSTRG.6960.2;MSTRG.6960.3;MSTRG.6960.4;MSTRG.6960.6;MSTRG.6960.8;MSTRG.6960.7;MSTRG.6960.10;MSTRG.6960.11;MSTRG.6960.9;MSTRG.6960.14;MSTRG.6960.12;MSTRG.6960.13;MSTRG.6960.15;MSTRG.6960.16	NA	NA	NA	NA	NA	72.5	37.75	36.47	18.28	10.78	10.06	3.77	1.91	0.04	0.33	up	yes
MSTRG.6962	BRI3BP	ENST00000341446;MSTRG.6962.2	NA	NA	NA	NA	NA	0.56	0.69	0.82	6.03	6.71	3.64	0.24	-2.08	0.01	0.19	down	yes
MSTRG.6984	RAN	ENST00000543796;ENST00000448750;ENST00000536606;ENST00000537745;ENST00000541630;ENST00000477395;ENST00000392369;ENST00000535090;ENST00000541679;ENST00000464211;ENST00000392367;ENST00000539498	"GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0000060(protein import into nucleus, translocation);GO:0000785(chromatin);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005814(centriole);GO:0005829(cytosol);GO:0006259(DNA metabolic process);GO:0006606(protein import into nucleus);GO:0006611(protein export from nucleus);GO:0006886(intracellular protein transport);GO:0006913(nucleocytoplasmic transport);GO:0007052(mitotic spindle organization);GO:0007067(mitotic nuclear division);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0010467(gene expression);GO:0015031(protein transport);GO:0016020(membrane);GO:0016032(viral process);GO:0019003(GDP binding);GO:0019058(viral life cycle);GO:0030496(midbody);GO:0030521(androgen receptor signaling pathway);GO:0032092(positive regulation of protein binding);GO:0035281(pre-miRNA export from nucleus);GO:0042470(melanosome);GO:0042565(RNA nuclear export complex);GO:0044281(small molecule metabolic process);GO:0044822(poly(A) RNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050681(androgen receptor binding);GO:0051301(cell division);GO:0055037(recycling endosome);GO:0070062(extracellular exosome);GO:0070883(pre-miRNA binding);GO:0075733(intracellular transport of virus);GO:1902570(protein localization to nucleolus)"	NA	NA	NA	"RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846]"	48.84	60.44	56.49	138.04	188.94	92.84	0.36	-1.49	0.03	0.3	down	yes
MSTRG.7008	POLE	ENST00000541627;ENST00000320574;ENST00000537064;ENST00000534922;ENST00000544692;ENST00000538196;ENST00000544870;MSTRG.7008.8;ENST00000441786;ENST00000541213;ENST00000544414;ENST00000416953;MSTRG.7008.14;ENST00000434528;ENST00000542362;ENST00000540987;ENST00000536445;ENST00000503265;ENST00000545015;ENST00000535934;ENST00000539618;ENST00000539357	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000166(nucleotide binding);GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0000731(DNA synthesis involved in DNA repair);GO:0001701(in utero embryonic development);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003887(DNA-directed DNA polymerase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006287(base-excision repair, gap-filling);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0008270(zinc ion binding);GO:0008408(3'-5' exonuclease activity);GO:0008622(epsilon DNA polymerase complex);GO:0032201(telomere maintenance via semi-conservative replication);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0071897(DNA biosynthetic process);GO:0090305(nucleic acid phosphodiester bond hydrolysis)"	00230(Purine metabolism);00240(Pyrimidine metabolism);01100(Metabolic pathways);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair)	NA	NA	"polymerase (DNA directed), epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177]"	0.6	0.76	0.77	5.04	4.13	4.27	0.29	-1.79	0	0.08	down	yes
MSTRG.702	AGO3	MSTRG.702.1	NA	NA	NA	NA	NA	3.71	4.66	1.94	0	0.3	0.47	3.67	1.88	0.03	0.28	up	yes
MSTRG.7079	FTH1P7	ENST00000450676	NA	NA	NA	NA	NA	5.39	4.2	5.15	0.76	0	1.18	4.11	2.04	0.02	0.28	up	yes
MSTRG.7080	SGCG	MSTRG.7080.1;MSTRG.7080.2;ENST00000218867	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0007517(muscle organ development);GO:0016011(dystroglycan complex);GO:0016012(sarcoglycan complex);GO:0016021(integral component of membrane);GO:0042383(sarcolemma);GO:0048738(cardiac muscle tissue development);GO:0055001(muscle cell development);GO:0060047(heart contraction);GO:0061024(membrane organization)	05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy);05416(Viral myocarditis)	NA	NA	"sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) [Source:HGNC Symbol;Acc:HGNC:10809]"	0.8	1.19	2.15	0.06	0	0.02	2.05	1.04	0.05	0.33	up	yes
MSTRG.7112	.	MSTRG.7112.1;MSTRG.7112.2	NA	NA	NA	NA	NA	3.09	2.66	2.41	0	0	0	3.87	1.95	0	0.1	up	yes
MSTRG.7130	FLT1	ENST00000282397;ENST00000615611;ENST00000543394;ENST00000541932;ENST00000615840;ENST00000539099	"GO:0002548(monocyte chemotaxis);GO:0004672(protein kinase activity);GO:0004713(protein tyrosine kinase activity);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005021(vascular endothelial growth factor-activated receptor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005615(extracellular space);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005925(focal adhesion);GO:0006468(protein phosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0010863(positive regulation of phospholipase C activity);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0016477(cell migration);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0019838(growth factor binding);GO:0030154(cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036323(vascular endothelial growth factor receptor-1 signaling pathway);GO:0036326(VEGF-A-activated receptor activity);GO:0036327(VEGF-B-activated receptor activity);GO:0036332(placental growth factor-activated receptor activity);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0043235(receptor complex);GO:0043406(positive regulation of MAP kinase activity);GO:0043410(positive regulation of MAPK cascade);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045766(positive regulation of angiogenesis);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0048598(embryonic morphogenesis)"	04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04510(Focal adhesion);05323(Rheumatoid arthritis)	NA	NA	fms-related tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763]	1.87	2.24	1.55	7.45	6.76	2.85	0.36	-1.46	0.04	0.33	down	yes
MSTRG.7142	B3GLCT	ENST00000343307;ENST00000461652	"GO:0005789(endoplasmic reticulum membrane);GO:0006004(fucose metabolic process);GO:0006493(protein O-linked glycosylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016757(transferase activity, transferring glycosyl groups);GO:0036066(protein O-linked fucosylation);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process)"	00514(Other types of O-glycan biosynthesis)	NA	NA	beta 3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:20207]	0.9	1.1	1.62	5.06	4.68	1.9	0.38	-1.4	0.05	0.34	down	yes
MSTRG.7145	FRY	ENST00000380250;ENST00000542859;ENST00000602645	GO:0000922(spindle pole);GO:0005488(binding);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center)	NA	NA	NA	furry homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:20367]	1.74	1.57	1.15	0.15	0.1	0.29	2.24	1.17	0.01	0.2	up	yes
MSTRG.7176	UFM1	ENST00000494372;ENST00000379649;ENST00000239878;ENST00000464423;ENST00000437952	GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034976(response to endoplasmic reticulum stress);GO:0070062(extracellular exosome);GO:0071569(protein ufmylation);GO:1990592(protein K69-linked ufmylation)	NA	NA	NA	ubiquitin-fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597]	17.93	22.38	20.99	9.9	8.7	4.52	2.01	1.01	0.05	0.34	up	yes
MSTRG.7177	FREM2	ENST00000280481;ENST00000482551	GO:0002009(morphogenesis of an epithelium);GO:0005509(calcium ion binding);GO:0005604(basement membrane);GO:0005886(plasma membrane);GO:0007154(cell communication);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0016021(integral component of membrane);GO:0048839(inner ear development);GO:0070062(extracellular exosome)	NA	NA	NA	FRAS1 related extracellular matrix protein 2 [Source:HGNC Symbol;Acc:HGNC:25396]	0.93	1.03	0.62	4.5	2.2	4.2	0.39	-1.35	0.04	0.31	down	yes
MSTRG.7204	KBTBD7	ENST00000379483	GO:0003674(molecular_function);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0008150(biological_process)	NA	NA	NA	kelch repeat and BTB (POZ) domain containing 7 [Source:HGNC Symbol;Acc:HGNC:25266]	0.52	0.73	0	3.11	2.19	1.26	0.37	-1.42	0.05	0.33	down	yes
MSTRG.7252	TPT1	ENST00000616577;ENST00000530705;ENST00000379056;ENST00000528619;ENST00000529421;ENST00000484604;ENST00000533567;ENST00000490277;ENST00000530245;ENST00000379060;ENST00000379055;ENST00000362607;ENST00000309246;ENST00000527226;ENST00000442760	GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005771(multivesicular body);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0008134(transcription factor binding);GO:0009615(response to virus);GO:0019827(stem cell maintenance);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0044822(poly(A) RNA binding);GO:0045298(tubulin complex);GO:0070062(extracellular exosome);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:2000384(negative regulation of ectoderm development)	NA	NA	NA	"tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]"	358.88	393.56	396.28	111.08	141.15	224.1	2.89	1.53	0.03	0.28	up	yes
MSTRG.7267	LCP1	ENST00000398576;ENST00000323076;MSTRG.7267.2;MSTRG.7267.4;MSTRG.7267.5;MSTRG.7267.6;ENST00000469227;ENST00000494531;ENST00000416500;ENST00000442275;ENST00000460190	GO:0001725(stress fiber);GO:0001726(ruffle);GO:0001891(phagocytic cup);GO:0002102(podosome);GO:0002286(T cell activation involved in immune response);GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005884(actin filament);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0010737(protein kinase A signaling);GO:0015629(actin cytoskeleton);GO:0016477(cell migration);GO:0022617(extracellular matrix disassembly);GO:0030175(filopodium);GO:0032432(actin filament bundle);GO:0032587(ruffle membrane);GO:0033157(regulation of intracellular protein transport);GO:0042802(identical protein binding);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly);GO:0051020(GTPase binding);GO:0070062(extracellular exosome);GO:0071803(positive regulation of podosome assembly)	NA	NA	NA	lymphocyte cytosolic protein 1 (L-plastin) [Source:HGNC Symbol;Acc:HGNC:6528]	6.55	7.99	9.83	1.76	2.27	0.66	3.06	1.61	0.03	0.28	up	yes
MSTRG.727	CDCA8	ENST00000373055;ENST00000327331	"GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005819(spindle);GO:0005829(cytosol);GO:0007080(mitotic metaphase plate congression);GO:0007264(small GTPase mediated signal transduction);GO:0010369(chromocenter);GO:0030496(midbody);GO:0032133(chromosome passenger complex);GO:0043234(protein complex);GO:0045171(intercellular bridge);GO:0051276(chromosome organization);GO:0051301(cell division)"	NA	NA	NA	cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629]	3.78	3.81	2.25	33.94	41.36	12.8	0.13	-2.98	0.03	0.28	down	yes
MSTRG.7296	.	MSTRG.7296.1;MSTRG.7296.2	NA	NA	NA	NA	NA	1.95	3.2	3.55	0.05	0.04	0.01	3.22	1.69	0	0.17	up	yes
MSTRG.730	YRDC	MSTRG.730.1;ENST00000373044	GO:0003725(double-stranded RNA binding);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0051051(negative regulation of transport)	NA	NA	NA	yrdC N(6)-threonylcarbamoyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:28905]	11.29	9.76	9.28	4.39	5.4	3.95	2.07	1.05	0.01	0.23	up	yes
MSTRG.7304	CAB39L	ENST00000355854;ENST00000610540;ENST00000409308;ENST00000409130;ENST00000425242;ENST00000410043;ENST00000413278;ENST00000409082;ENST00000476943;ENST00000470410;MSTRG.7304.13	NA	NA	NA	NA	NA	2.28	2.5	1.55	0.48	0.46	0.45	2.08	1.05	0.01	0.24	up	yes
MSTRG.7305	SNRPGP14	MSTRG.7305.1;MSTRG.7305.2;ENST00000354234;ENST00000481439;ENST00000258672;ENST00000317257;ENST00000435400	NA	NA	NA	NA	NA	5.19	4.93	3.04	1.39	0.96	0.44	2.54	1.34	0.04	0.33	up	yes
MSTRG.7335	DLEU7	MSTRG.7335.1	NA	NA	NA	NA	NA	0.17	0.11	0	1.17	1.72	0.81	0.49	-1.03	0.03	0.29	down	yes
MSTRG.7380	KLF5	ENST00000477333;ENST00000539231;ENST00000377687;MSTRG.7380.4;ENST00000476859;ENST00000464404	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0001525(angiogenesis);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0030033(microvillus assembly);GO:0032534(regulation of microvillus assembly);GO:0035914(skeletal muscle cell differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:0045600(positive regulation of fat cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0060576(intestinal epithelial cell development)"	NA	NA	NA	Kruppel-like factor 5 (intestinal) [Source:HGNC Symbol;Acc:HGNC:6349]	41.29	53.37	34.69	2.94	8.87	3.85	7.73	2.95	0.02	0.26	up	yes
MSTRG.7387	TBC1D4	MSTRG.7387.1;ENST00000377625;ENST00000377636;ENST00000478591;ENST00000493487;ENST00000413735	GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016192(vesicle-mediated transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031339(negative regulation of vesicle fusion);GO:0031988(membrane-bounded vesicle);GO:0032869(cellular response to insulin stimulus);GO:0043547(positive regulation of GTPase activity);GO:0061024(membrane organization);GO:0070062(extracellular exosome)	NA	NA	NA	"TBC1 domain family, member 4 [Source:HGNC Symbol;Acc:HGNC:19165]"	2.34	1.94	2.66	8.98	6.25	6.86	0.39	-1.38	0.01	0.23	down	yes
MSTRG.7415	RNF219	ENST00000282003	"GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0048026(positive regulation of mRNA splicing, via spliceosome)"	NA	NA	NA	ring finger protein 219 [Source:HGNC Symbol;Acc:HGNC:20308]	1.23	6.39	4.16	8.2	5.24	1.47	0.4	-1.32	0.04	0.31	down	yes
MSTRG.7457	.	MSTRG.7457.1;MSTRG.7457.3;MSTRG.7457.2;MSTRG.7457.4;ENST00000437334;MSTRG.7457.6	NA	NA	NA	NA	NA	0.26	0.21	0.13	3.12	2.06	2.23	0.33	-1.6	0	0.17	down	yes
MSTRG.7506	.	MSTRG.7506.1;MSTRG.7506.2	NA	NA	NA	NA	NA	3.38	0.92	0.88	0.08	0.46	0.76	2.74	1.46	0.01	0.23	up	yes
MSTRG.7507	LINC00460	MSTRG.7507.1;MSTRG.7507.2;MSTRG.7507.3;MSTRG.7507.4;ENST00000439790;ENST00000435024;ENST00000444865	NA	NA	NA	NA	NA	10.6	15.43	18.13	3.17	5.58	4.66	2.76	1.47	0.04	0.31	up	yes
MSTRG.7520	RP11-54H7.4	MSTRG.7520.1;MSTRG.7520.2;ENST00000618966	NA	NA	NA	NA	NA	5.94	10.88	6.8	0.7	1.28	0.06	4.11	2.04	0.02	0.26	up	yes
MSTRG.7536	ING1	ENST00000338450;ENST00000333219;ENST00000375774	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0006606(protein import into nucleus);GO:0007049(cell cycle);GO:0008270(zinc ion binding);GO:0008285(negative regulation of cell proliferation);GO:0010941(regulation of cell death);GO:0016568(chromatin modification);GO:0030308(negative regulation of cell growth);GO:0035064(methylated histone binding);GO:0045893(positive regulation of transcription, DNA-templated)"	NA	NA	NA	"inhibitor of growth family, member 1 [Source:HGNC Symbol;Acc:HGNC:6062]"	4.86	5.58	4.18	1.21	0.94	1.13	4.46	2.16	0.04	0.33	up	yes
MSTRG.7539	ANKRD10-IT1	ENST00000426991	NA	NA	NA	NA	NA	8.74	5.07	5.26	2.82	1.99	2.15	2.43	1.28	0.03	0.28	up	yes
MSTRG.7568	TFDP1	MSTRG.7568.1;ENST00000475254;MSTRG.7568.2;ENST00000464794;ENST00000375370;ENST00000465174;MSTRG.7568.7;MSTRG.7568.9;MSTRG.7568.8;ENST00000544902;ENST00000408980;ENST00000453989;MSTRG.7568.12;ENST00000494812	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000981(sequence-specific DNA binding RNA polymerase II transcription factor activity);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0007049(cell cycle);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007219(Notch signaling pathway);GO:0008134(transcription factor binding);GO:0008283(cell proliferation);GO:0010467(gene expression);GO:0012501(programmed cell death);GO:0019904(protein domain specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070345(negative regulation of fat cell proliferation);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)"	04110(Cell cycle);04350(TGF-beta signaling pathway)	NA	NA	transcription factor Dp-1 [Source:HGNC Symbol;Acc:HGNC:11749]	3.35	5.02	7.39	33.21	24.15	15.51	0.18	-2.46	0.01	0.21	down	yes
MSTRG.7577	CHAMP1	MSTRG.7577.1;MSTRG.7577.2;ENST00000361283	GO:0000777(condensed chromosome kinetochore);GO:0000793(condensed chromosome);GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0031134(sister chromatid biorientation);GO:0034501(protein localization to kinetochore);GO:0035372(protein localization to microtubule);GO:0046872(metal ion binding);GO:0051315(attachment of mitotic spindle microtubules to kinetochore)	NA	NA	NA	chromosome alignment maintaining phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:20311]	2.24	2.49	2.34	12.79	10.65	6	0.27	-1.91	0.01	0.23	down	yes
MSTRG.7599	OSGEP	ENST00000555656;ENST00000206542;ENST00000556124;ENST00000553292;ENST00000554249;ENST00000555223;ENST00000555785;ENST00000554915;ENST00000553640;ENST00000554699;ENST00000556439;ENST00000556252	"GO:0000408(EKC/KEOPS complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016746(transferase activity, transferring acyl groups);GO:0046872(metal ion binding);GO:0070526(threonylcarbamoyladenosine biosynthetic process)"	NA	NA	NA	O-sialoglycoprotein endopeptidase [Source:HGNC Symbol;Acc:HGNC:18028]	1.12	1	1.68	3.15	4.87	3.56	0.49	-1.02	0.03	0.3	down	yes
MSTRG.7617	ARHGEF40	MSTRG.7617.1;MSTRG.7617.2;ENST00000298694;ENST00000555038;ENST00000556399;ENST00000553709;ENST00000555232;MSTRG.7617.8;ENST00000555052;ENST00000554514;ENST00000557498	GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity)	NA	NA	NA	Rho guanine nucleotide exchange factor (GEF) 40 [Source:HGNC Symbol;Acc:HGNC:25516]	3.3	2.49	3.71	8.78	7.59	11.4	0.46	-1.13	0.02	0.26	down	yes
MSTRG.7624	CHD8	ENST00000430710;ENST00000399982;MSTRG.7624.2;MSTRG.7624.4;ENST00000557727;MSTRG.7624.5;ENST00000557364;ENST00000553870;ENST00000555301;ENST00000557329;ENST00000555962;ENST00000555935;ENST00000554384;ENST00000553283;ENST00000553622;ENST00000556833;ENST00000553651	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002039(p53 binding);GO:0003677(DNA binding);GO:0003678(DNA helicase activity);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0007420(brain development);GO:0008013(beta-catenin binding);GO:0008094(DNA-dependent ATPase activity);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0030178(negative regulation of Wnt signaling pathway);GO:0032508(DNA duplex unwinding);GO:0035064(methylated histone binding);GO:0042393(histone binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0048565(digestive tract development);GO:0060070(canonical Wnt signaling pathway);GO:0071339(MLL1 complex);GO:0090090(negative regulation of canonical Wnt signaling pathway)"	04310(Wnt signaling pathway)	NA	NA	chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]	3.04	4.63	5.13	10.86	8.99	6.16	0.43	-1.23	0.01	0.23	down	yes
MSTRG.7635	ABHD4	ENST00000428304;MSTRG.7635.2;ENST00000537243;ENST00000544562;MSTRG.7635.4;ENST00000542041;ENST00000539344;ENST00000216327;ENST00000545034	GO:0016042(lipid catabolic process);GO:0016787(hydrolase activity)	NA	NA	NA	abhydrolase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:20154]	26.4	26.5	18.2	6.15	5.15	4.39	3.7	1.89	0.01	0.2	up	yes
MSTRG.7702	RP11-104E19.1	MSTRG.7702.1;ENST00000557736;MSTRG.7702.3;ENST00000555300	NA	NA	NA	NA	NA	0.15	0.16	0.67	3.69	3.19	3.75	0.28	-1.83	0.01	0.2	down	yes
MSTRG.7707	HMGN2P6	MSTRG.7707.1	NA	NA	NA	NA	NA	1.57	2.19	1.74	4.15	5.47	2.75	0.49	-1.02	0.04	0.33	down	yes
MSTRG.7710	CTD-2591A6.2	MSTRG.7710.2;MSTRG.7710.1;ENST00000548280	NA	NA	NA	NA	NA	3.76	3.03	2.04	0.92	0.68	1.41	2.2	1.14	0.04	0.3	up	yes
MSTRG.7716	FOXG1	MSTRG.7716.1;ENST00000313071;MSTRG.7716.3	NA	NA	NA	NA	NA	2.96	1.81	2.54	0	0.78	2.33	2.88	1.52	0.05	0.33	up	yes
MSTRG.7777	SRP54-AS1	MSTRG.7777.1	NA	NA	NA	NA	NA	3.3	2.43	2.37	0.52	0.19	0.38	2.84	1.51	0.01	0.19	up	yes
MSTRG.7790	NFKBIA	ENST00000216797;ENST00000557140;ENST00000557389;ENST00000555371;ENST00000557100;ENST00000556664;ENST00000557459;ENST00000555629	"GO:0000060(protein import into nucleus, translocation);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0008134(transcription factor binding);GO:0008139(nuclear localization sequence binding);GO:0010468(regulation of gene expression);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010888(negative regulation of lipid storage);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0031072(heat shock protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032403(protein complex binding);GO:0032481(positive regulation of type I interferon production);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0033256(I-kappaB/NF-kappaB complex);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0034146(toll-like receptor 5 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0035994(response to muscle stretch);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0042127(regulation of cell proliferation);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0042802(identical protein binding);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0043066(negative regulation of apoptotic process);GO:0043234(protein complex);GO:0043330(response to exogenous dsRNA);GO:0043392(negative regulation of DNA binding);GO:0045087(innate immune response);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0051059(NF-kappaB binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070417(cellular response to cold);GO:0070427(nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway)"	04062(Chemokine signaling pathway);04210(Apoptosis);04380(Osteoclast differentiation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04722(Neurotrophin signaling pathway);04920(Adipocytokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05160(Hepatitis C);05162(Measles);05164(Influenza A);05200(Pathways in cancer);05215(Prostate cancer);05220(Chronic myeloid leukemia);05222(Small cell lung cancer)	NA	NA	"nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [Source:HGNC Symbol;Acc:HGNC:7797]"	106.28	45.25	133.08	12.86	12.24	34.57	7.56	2.92	0.02	0.27	up	yes
MSTRG.7814	CTAGE5	ENST00000553728;ENST00000554392;ENST00000555716;ENST00000341749;ENST00000557038;ENST00000396165;MSTRG.7814.11;ENST00000556990;ENST00000396158;ENST00000280083;ENST00000341502;ENST00000556148;ENST00000348007;ENST00000553352;ENST00000556593;ENST00000553383	GO:0005515(protein binding);GO:0008047(enzyme activator activity);GO:0016020(membrane);GO:0043085(positive regulation of catalytic activity)	NA	NA	NA	"CTAGE family, member 5 [Source:HGNC Symbol;Acc:HGNC:7057]"	6.56	7.32	6.64	1.68	1.21	0.75	3.21	1.68	0	0.17	up	yes
MSTRG.7822	KLHL28	ENST00000396128;ENST00000355081;ENST00000579157;ENST00000556500;ENST00000556239;ENST00000557468	GO:0005515(protein binding)	NA	NA	NA	kelch-like family member 28 [Source:HGNC Symbol;Acc:HGNC:19741]	2.96	2.93	1.8	0.27	0.66	0.56	2.6	1.38	0.02	0.25	up	yes
MSTRG.7840	POLE2	ENST00000554851;ENST00000556937;ENST00000216367;ENST00000554671;ENST00000555724;ENST00000539565;ENST00000554377;ENST00000554396;ENST00000553850;ENST00000553805	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000722(telomere maintenance via recombination);GO:0000723(telomere maintenance);GO:0003677(DNA binding);GO:0003887(DNA-directed DNA polymerase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006270(DNA replication initiation);GO:0006281(DNA repair);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006289(nucleotide-excision repair);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0008622(epsilon DNA polymerase complex);GO:0032201(telomere maintenance via semi-conservative replication);GO:0042276(error-prone translesion synthesis);GO:0043231(intracellular membrane-bounded organelle)"	00230(Purine metabolism);00240(Pyrimidine metabolism);01100(Metabolic pathways);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair)	K00961;K02319;K02320;K02322;K02323;K02324;K02325;K02326;K02327;K02331;K02332;K02334;K02335;K02336;K02337;K02338;K02339;K02340;K02341;K02342;K02343;K02344;K02345;K02346;K02349;K02350;K03506;K03508;K03509;K03510;K03511;K03513;K03763;K04330;K04474;K04475;K04476;K04479;K04481;K10981;K14162;K16618;K18942;K18963;K18964	2.7.7.7	"polymerase (DNA directed), epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178]"	0.15	0.26	0.31	2.76	2.15	0.89	0.36	-1.48	0.02	0.27	down	yes
MSTRG.789	RIMS3	ENST00000372684;ENST00000372683	GO:0005515(protein binding);GO:0006836(neurotransmitter transport);GO:0017156(calcium ion-dependent exocytosis);GO:0030054(cell junction);GO:0042391(regulation of membrane potential);GO:0044325(ion channel binding);GO:0048786(presynaptic active zone);GO:0098779(activation of mitophagy in response to mitochondrial depolarization);GO:2000300(regulation of synaptic vesicle exocytosis)	NA	NA	NA	regulating synaptic membrane exocytosis 3 [Source:HGNC Symbol;Acc:HGNC:21292]	3.78	4.78	1.57	0.31	0.22	0.28	3.1	1.63	0.05	0.34	up	yes
MSTRG.7915	WDHD1	ENST00000360586;ENST00000420358;ENST00000567693;ENST00000455555	"GO:0000775(chromosome, centromeric region);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0033044(regulation of chromosome organization);GO:0070063(RNA polymerase binding);GO:0070829(heterochromatin maintenance)"	NA	NA	NA	WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170]	0.88	1.54	0.95	4.63	3.22	1.33	0.4	-1.33	0.04	0.31	down	yes
MSTRG.7919	LGALS3	ENST00000553493;ENST00000254301;MSTRG.7919.3;ENST00000553755;ENST00000554715;ENST00000556438;ENST00000556322;ENST00000556263	GO:0001501(skeletal system development);GO:0001772(immunological synapse);GO:0002548(monocyte chemotaxis);GO:0005515(protein binding);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005743(mitochondrial inner membrane);GO:0005886(plasma membrane);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0009897(external side of plasma membrane);GO:0016020(membrane);GO:0019863(IgE binding);GO:0030198(extracellular matrix organization);GO:0030246(carbohydrate binding);GO:0030593(neutrophil chemotaxis);GO:0030855(epithelial cell differentiation);GO:0031012(extracellular matrix);GO:0042056(chemoattractant activity);GO:0042129(regulation of T cell proliferation);GO:0043236(laminin binding);GO:0044822(poly(A) RNA binding);GO:0045087(innate immune response);GO:0045806(negative regulation of endocytosis);GO:0048245(eosinophil chemotaxis);GO:0048246(macrophage chemotaxis);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0050918(positive chemotaxis);GO:0070062(extracellular exosome);GO:0070232(regulation of T cell apoptotic process);GO:0071674(mononuclear cell migration);GO:0071677(positive regulation of mononuclear cell migration);GO:0090280(positive regulation of calcium ion import);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2000521(negative regulation of immunological synapse formation);GO:2001189(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)	NA	NA	NA	"lectin, galactoside-binding, soluble, 3 [Source:HGNC Symbol;Acc:HGNC:6563]"	70.64	56.8	49.41	7.8	5.66	10.53	7.71	2.95	0	0.17	up	yes
MSTRG.7927	ATG14	MSTRG.7927.1;ENST00000558189;ENST00000247178	"GO:0000045(autophagosome assembly);GO:0000421(autophagosome membrane);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005776(autophagosome);GO:0005930(axoneme);GO:0006914(autophagy);GO:0008333(endosome to lysosome transport);GO:0010508(positive regulation of autophagy);GO:0010608(posttranscriptional regulation of gene expression);GO:0016236(macroautophagy);GO:0034045(pre-autophagosomal structure membrane);GO:0035032(phosphatidylinositol 3-kinase complex, class III);GO:0042149(cellular response to glucose starvation);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0044233(ER-mitochondrion membrane contact site);GO:0045335(phagocytic vesicle);GO:0061635(regulation of protein complex stability);GO:0090207(regulation of triglyceride metabolic process);GO:0097629(extrinsic component of omegasome membrane);GO:0097632(extrinsic component of pre-autophagosomal structure membrane);GO:0098779(activation of mitophagy in response to mitochondrial depolarization)"	NA	NA	NA	autophagy related 14 [Source:HGNC Symbol;Acc:HGNC:19962]	9.22	4.09	6.56	0.9	2.86	4.14	3.62	1.86	0.01	0.19	up	yes
MSTRG.797	CTPS1	ENST00000372621;MSTRG.797.2;ENST00000470271;ENST00000475060;ENST00000479480;ENST00000372616;ENST00000480420;ENST00000463285;ENST00000486889;ENST00000497210;ENST00000464283;ENST00000463423;ENST00000498694	GO:0003883(CTP synthase activity);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0006541(glutamine metabolic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016020(membrane);GO:0042098(T cell proliferation);GO:0042100(B cell proliferation);GO:0042493(response to drug);GO:0044210('de novo' CTP biosynthetic process);GO:0044281(small molecule metabolic process);GO:0055086(nucleobase-containing small molecule metabolic process)	00240(Pyrimidine metabolism);01100(Metabolic pathways)	NA	NA	CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519]	6.59	7.58	11.3	27.79	27.14	17.41	0.32	-1.64	0.02	0.26	down	yes
MSTRG.803	HIVEP3	ENST00000372583;ENST00000372584;ENST00000247584;ENST00000460604;MSTRG.803.5;MSTRG.803.6;MSTRG.803.7;MSTRG.803.8;ENST00000491442;ENST00000489103;ENST00000479350	"GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0035914(skeletal muscle cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046872(metal ion binding)"	NA	NA	NA	human immunodeficiency virus type I enhancer binding protein 3 [Source:HGNC Symbol;Acc:HGNC:13561]	0.43	0.4	0.34	3.48	2.39	3.17	0.34	-1.55	0	0.17	down	yes
MSTRG.8033	FNTB	ENST00000549115;ENST00000607599;ENST00000548752;ENST00000552002;ENST00000551947;ENST00000359118;ENST00000556089;ENST00000551093;ENST00000552941;ENST00000549987;ENST00000547625;ENST00000551823;ENST00000246166;ENST00000555372;ENST00000555742;MSTRG.8033.17;ENST00000554210;ENST00000554334;ENST00000556709;ENST00000555618;ENST00000557300	"GO:0003824(catalytic activity);GO:0004311(farnesyltranstransferase activity);GO:0004660(protein farnesyltransferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005875(microtubule associated complex);GO:0005965(protein farnesyltransferase complex);GO:0007603(phototransduction, visible light);GO:0008144(drug binding);GO:0008270(zinc ion binding);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0010035(response to inorganic substance);GO:0014070(response to organic cyclic compound);GO:0016056(rhodopsin mediated signaling pathway);GO:0018343(protein farnesylation);GO:0019840(isoprenoid binding);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0034097(response to cytokine);GO:0042060(wound healing);GO:0042277(peptide binding);GO:0043234(protein complex);GO:0045787(positive regulation of cell cycle);GO:0048146(positive regulation of fibroblast proliferation);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process)"	NA	NA	NA	"farnesyltransferase, CAAX box, beta [Source:HGNC Symbol;Acc:HGNC:3785]"	2.21	2.41	2.47	5.97	5.49	4.52	0.49	-1.02	0	0.16	down	yes
MSTRG.8035	RAB15	ENST00000267512;ENST00000533601;MSTRG.8035.3;ENST00000585059;ENST00000426039;ENST00000554593;ENST00000555256	GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005525(GTP binding);GO:0005622(intracellular);GO:0005623(cell);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006886(intracellular protein transport);GO:0006904(vesicle docking involved in exocytosis);GO:0006913(nucleocytoplasmic transport);GO:0007165(signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0008152(metabolic process);GO:0009306(protein secretion);GO:0010008(endosome membrane);GO:0015031(protein transport);GO:0016020(membrane);GO:0032482(Rab protein signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0072372(primary cilium);GO:0072659(protein localization to plasma membrane);GO:1903307(positive regulation of regulated secretory pathway)	NA	NA	NA	"RAB15, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20150]"	3.07	2.34	2.2	10.01	10.39	8.02	0.35	-1.53	0.01	0.19	down	yes
MSTRG.8060	ARG2	ENST00000261783;ENST00000557120;ENST00000556491;ENST00000557319	"GO:0000050(urea cycle);GO:0001657(ureteric bud development);GO:0004053(arginase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006525(arginine metabolic process);GO:0006809(nitric oxide biosynthetic process);GO:0006941(striated muscle contraction);GO:0016813(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines);GO:0034641(cellular nitrogen compound metabolic process);GO:0044281(small molecule metabolic process);GO:0046872(metal ion binding)"	00330(Arginine and proline metabolism);01100(Metabolic pathways);05146(Amoebiasis)	NA	NA	arginase 2 [Source:HGNC Symbol;Acc:HGNC:664]	11.68	16.52	16.64	4.23	2.76	5.74	2.87	1.52	0.03	0.3	up	yes
MSTRG.8081	ZFP36L1	ENST00000555997;ENST00000439696;MSTRG.8081.2;ENST00000336440;ENST00000557086;ENST00000557022;ENST00000553375	"GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0001570(vasculogenesis);GO:0003342(proepicardium development);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006402(mRNA catabolic process);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0010467(gene expression);GO:0017091(AU-rich element binding);GO:0021915(neural tube development);GO:0033077(T cell differentiation in thymus);GO:0035264(multicellular organism growth);GO:0043488(regulation of mRNA stability);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding);GO:0048568(embryonic organ development);GO:0060710(chorio-allantoic fusion);GO:0060712(spongiotrophoblast layer development)"	NA	NA	NA	ZFP36 ring finger protein-like 1 [Source:HGNC Symbol;Acc:HGNC:1107]	35.06	22.5	22.21	6.81	5.64	12.24	4	2	0.01	0.23	up	yes
MSTRG.8124	ZFYVE1	ENST00000553891;ENST00000318876;ENST00000556143;ENST00000556040;ENST00000556761;ENST00000554145;ENST00000554250	"GO:0000407(pre-autophagosomal structure);GO:0005515(protein binding);GO:0005545(1-phosphatidylinositol binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0005776(autophagosome);GO:0005783(endoplasmic reticulum);GO:0005795(Golgi stack);GO:0008270(zinc ion binding);GO:0010923(negative regulation of phosphatase activity);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0044233(ER-mitochondrion membrane contact site);GO:0046872(metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0097629(extrinsic component of omegasome membrane)"	NA	NA	NA	"zinc finger, FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13180]"	8.33	6.1	7.23	2.79	3.67	6.62	2.08	1.06	0.03	0.29	up	yes
MSTRG.8175	YLPM1	ENST00000552421;ENST00000325680;ENST00000549293;ENST00000547879;ENST00000554107;ENST00000546901;ENST00000550021;ENST00000549197	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0008150(biological_process);GO:0016607(nuclear speck);GO:0032204(regulation of telomere maintenance);GO:0044822(poly(A) RNA binding)"	NA	NA	NA	YLP motif containing 1 [Source:HGNC Symbol;Acc:HGNC:17798]	1.93	2.48	2.98	6.53	5.34	4.46	0.46	-1.12	0.01	0.2	down	yes
MSTRG.8189	JDP2	ENST00000419727;ENST00000559773;ENST00000559060;ENST00000437176;ENST00000435893;MSTRG.8189.7;ENST00000267569	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031063(regulation of histone deacetylation);GO:0031065(positive regulation of histone deacetylation);GO:0043565(sequence-specific DNA binding);GO:0045599(negative regulation of fat cell differentiation);GO:0046982(protein heterodimerization activity)"	NA	NA	NA	Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546]	2.32	2.18	1.48	0.16	0.43	0.32	2.44	1.29	0.01	0.21	up	yes
MSTRG.819	RP5-994D16.11	MSTRG.819.1;ENST00000372525;ENST00000464081;ENST00000603943;ENST00000468913;ENST00000494155;ENST00000536543	NA	NA	NA	NA	NA	4.73	3.35	2.84	1.22	1.29	1.35	2.32	1.21	0.01	0.21	up	yes
MSTRG.8284	TDP1	ENST00000554976;ENST00000393452;ENST00000554180;ENST00000393454;ENST00000553617;ENST00000335725;ENST00000555565;ENST00000556867;ENST00000553569;ENST00000553527;MSTRG.8284.11;ENST00000553989;ENST00000545686;ENST00000555178;ENST00000556498;ENST00000555880;ENST00000557782;ENST00000556063	GO:0000012(single strand break repair);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0004527(exonuclease activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0008081(phosphoric diester hydrolase activity);GO:0017005(3'-tyrosyl-DNA phosphodiesterase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis)	NA	NA	NA	tyrosyl-DNA phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:18884]	1.51	1.83	1.74	5.11	6.52	3.89	0.41	-1.3	0.01	0.24	down	yes
MSTRG.8304	MOAP1	ENST00000298894;ENST00000556883	GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0031625(ubiquitin protein ligase binding);GO:0043065(positive regulation of apoptotic process);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097190(apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand)	NA	NA	NA	modulator of apoptosis 1 [Source:HGNC Symbol;Acc:HGNC:16658]	19.45	19.03	16.35	6.54	6.43	11.07	2.47	1.31	0.02	0.27	up	yes
MSTRG.8315	PRIMA1	ENST00000393143;ENST00000393140;ENST00000477603	GO:0016021(integral component of membrane);GO:0019899(enzyme binding);GO:0030054(cell junction);GO:0031226(intrinsic component of plasma membrane);GO:0042135(neurotransmitter catabolic process);GO:0043495(protein anchor);GO:0045202(synapse);GO:0051649(establishment of localization in cell)	NA	NA	NA	proline rich membrane anchor 1 [Source:HGNC Symbol;Acc:HGNC:18319]	0.05	0.01	0.08	1.23	1.1	1.23	0.48	-1.05	0	0.1	down	yes
MSTRG.834	CDC20	ENST00000310955;ENST00000372462;ENST00000478882;ENST00000482046	GO:0000278(mitotic cell cycle);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005680(anaphase-promoting complex);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005819(spindle);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0007067(mitotic nuclear division);GO:0007094(mitotic spindle assembly checkpoint);GO:0007264(small GTPase mediated signal transduction);GO:0008022(protein C-terminus binding);GO:0008284(positive regulation of cell proliferation);GO:0016567(protein ubiquitination);GO:0019899(enzyme binding);GO:0031145(anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031915(positive regulation of synaptic plasticity);GO:0040020(regulation of meiotic nuclear division);GO:0042826(histone deacetylase binding);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0050773(regulation of dendrite development);GO:0051301(cell division);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051488(activation of anaphase-promoting complex activity);GO:0090129(positive regulation of synapse maturation)	04110(Cell cycle);04114(Oocyte meiosis);04120(Ubiquitin mediated proteolysis)	NA	NA	cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723]	24.01	17.63	10.68	159.3	197.61	66.76	0.13	-2.97	0.04	0.31	down	yes
MSTRG.8364	SLC25A29	ENST00000553954;ENST00000359232;ENST00000554912;MSTRG.8364.4;MSTRG.8364.3;ENST00000392908;ENST00000556505;ENST00000554224;ENST00000556715;ENST00000554291;ENST00000554060;ENST00000556868;ENST00000555475;ENST00000556873;ENST00000553574;ENST00000555051;ENST00000557438;ENST00000555888;ENST00000556201;ENST00000556844	GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006810(transport);GO:0006844(acyl carnitine transport);GO:0015227(acyl carnitine transmembrane transporter activity);GO:0016021(integral component of membrane);GO:1902616(acyl carnitine transmembrane transport)	NA	NA	NA	"solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 [Source:HGNC Symbol;Acc:HGNC:20116]"	3.34	1.49	3.28	0.89	1.13	1.44	2.14	1.1	0.02	0.25	up	yes
MSTRG.8366	WARS	MSTRG.8366.3;MSTRG.8366.2;MSTRG.8366.1;ENST00000392882;MSTRG.8366.4;ENST00000358655;ENST00000355338;ENST00000344102;ENST00000557135;ENST00000556645;ENST00000554950;ENST00000557614;ENST00000554601;ENST00000553395;ENST00000556504;ENST00000554084;ENST00000557722;ENST00000557297;ENST00000556435;ENST00000553808;ENST00000554331;ENST00000555063;ENST00000556338;ENST00000556698;ENST00000557239;ENST00000553524;ENST00000555410;ENST00000556579;ENST00000554772;ENST00000556660;ENST00000556783;ENST00000553413;ENST00000557094;ENST00000553769;ENST00000554820;ENST00000557347;ENST00000554509;ENST00000556209;ENST00000554605;ENST00000555813;ENST00000556295;ENST00000555031;ENST00000553934;ENST00000553581;ENST00000555464	GO:0000166(nucleotide binding);GO:0001525(angiogenesis);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004830(tryptophan-tRNA ligase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006412(translation);GO:0006418(tRNA aminoacylation for protein translation);GO:0006436(tryptophanyl-tRNA aminoacylation);GO:0008152(metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0010467(gene expression);GO:0045765(regulation of angiogenesis);GO:0070062(extracellular exosome)	00380(Tryptophan metabolism);00970(Aminoacyl-tRNA biosynthesis)	NA	NA	tryptophanyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12729]	103	99.43	168.13	25.15	18.04	32.86	4.89	2.29	0.02	0.26	up	yes
MSTRG.837	MED8	MSTRG.837.1;ENST00000290663;ENST00000372457;ENST00000372455;ENST00000460803;ENST00000473560	GO:0001104(RNA polymerase II transcription cofactor activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0010467(gene expression);GO:0016567(protein ubiquitination);GO:0016592(mediator complex)	NA	NA	NA	mediator complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:19971]	64.62	61.97	60.59	22.33	23.21	20.11	2.76	1.46	0	0.12	up	yes
MSTRG.838	RP1-92O14.6	ENST00000436713	NA	NA	NA	NA	NA	3.02	2.88	5.36	0.56	0.38	0.42	3.08	1.62	0.02	0.25	up	yes
MSTRG.8433	INF2	MSTRG.8433.1;ENST00000540171;MSTRG.8433.3;MSTRG.8433.4;ENST00000330634;ENST00000398337;ENST00000392634;ENST00000252527;ENST00000617571;ENST00000474229;ENST00000480763;ENST00000477497;ENST00000481338	GO:0003779(actin binding);GO:0005488(binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0030036(actin cytoskeleton organization);GO:0032535(regulation of cellular component size);GO:0048471(perinuclear region of cytoplasm);GO:0090140(regulation of mitochondrial fission)	NA	NA	NA	"inverted formin, FH2 and WH2 domain containing [Source:HGNC Symbol;Acc:HGNC:23791]"	9.92	7.43	5.99	3.79	3.31	4.47	2.02	1.02	0.03	0.28	up	yes
MSTRG.8441	AHNAK2	ENST00000555122;MSTRG.8441.2;ENST00000557457;MSTRG.8441.3;MSTRG.8441.5;ENST00000333244;ENST00000555544	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0030018(Z disc);GO:0030315(T-tubule);GO:0030659(cytoplasmic vesicle membrane);GO:0042383(sarcolemma);GO:0043034(costamere)	NA	NA	NA	AHNAK nucleoprotein 2 [Source:HGNC Symbol;Acc:HGNC:20125]	9.95	9.59	11.41	2.16	1.15	0.88	4.23	2.08	0.01	0.19	up	yes
MSTRG.8443	CDCA4	ENST00000336219;ENST00000392590	GO:0005515(protein binding);GO:0005634(nucleus)	NA	NA	NA	cell division cycle associated 4 [Source:HGNC Symbol;Acc:HGNC:14625]	6.25	10.54	8.72	19.49	23.26	13.17	0.38	-1.38	0.02	0.25	down	yes
MSTRG.860	SLC6A9	ENST00000372307;ENST00000372306;ENST00000372310;MSTRG.860.4;ENST00000475075;ENST00000357730;ENST00000360584;ENST00000492434;ENST00000489764;ENST00000466926;ENST00000533007	GO:0003333(amino acid transmembrane transport);GO:0005283(sodium:amino acid symporter activity);GO:0005328(neurotransmitter:sodium symporter activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006810(transport);GO:0006836(neurotransmitter transport);GO:0015187(glycine transmembrane transporter activity);GO:0015375(glycine:sodium symporter activity);GO:0015816(glycine transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport)	NA	NA	NA	"solute carrier family 6 (neurotransmitter transporter, glycine), member 9 [Source:HGNC Symbol;Acc:HGNC:11056]"	8.71	7.61	10.05	2.65	2.63	1.55	2.87	1.52	0.01	0.23	up	yes
MSTRG.8691	HERC2	ENST00000261609;MSTRG.8691.2;ENST00000562136;ENST00000568206;ENST00000564519;ENST00000569772;ENST00000567869;ENST00000569335;ENST00000564734;ENST00000563670;ENST00000564383;ENST00000563945	GO:0004842(ubiquitin-protein transferase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005743(mitochondrial inner membrane);GO:0005814(centriole);GO:0006281(DNA repair);GO:0006886(intracellular protein transport);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0016925(protein sumoylation);GO:0031625(ubiquitin protein ligase binding);GO:0032183(SUMO binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043547(positive regulation of GTPase activity);GO:0043687(post-translational protein modification);GO:0044267(cellular protein metabolic process);GO:0046872(metal ion binding)	04120(Ubiquitin mediated proteolysis)	NA	NA	HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868]	1.45	1.72	2.92	5.49	4.37	4.7	0.46	-1.11	0.03	0.3	down	yes
MSTRG.870	KIF2C	MSTRG.870.1;ENST00000372224;ENST00000493027;MSTRG.870.5;ENST00000455186;ENST00000480574;ENST00000372217;ENST00000423289;ENST00000472235	"GO:0000278(mitotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0003777(microtubule motor activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0005874(microtubule);GO:0005881(cytoplasmic microtubule);GO:0007018(microtubule-based movement);GO:0007019(microtubule depolymerization);GO:0007067(mitotic nuclear division);GO:0007080(mitotic metaphase plate congression);GO:0007264(small GTPase mediated signal transduction);GO:0007596(blood coagulation);GO:0008017(microtubule binding);GO:0008152(metabolic process);GO:0008283(cell proliferation);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0016887(ATPase activity);GO:0019237(centromeric DNA binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030951(establishment or maintenance of microtubule cytoskeleton polarity);GO:0035371(microtubule plus-end);GO:0051010(microtubule plus-end binding);GO:0051301(cell division);GO:0051983(regulation of chromosome segregation)"	NA	NA	NA	kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393]	8.42	5.75	2.91	49.15	67.45	22.76	0.14	-2.81	0.04	0.33	down	yes
MSTRG.8739	KLF13	ENST00000307145;ENST00000618680;ENST00000560473;ENST00000558844;ENST00000558673;ENST00000500533	GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:0045647(negative regulation of erythrocyte differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding)	NA	NA	NA	Kruppel-like factor 13 [Source:HGNC Symbol;Acc:HGNC:13672]	6.31	5.65	5.81	2.15	1.81	1.98	2.37	1.25	0	0.12	up	yes
MSTRG.874	PLK3	MSTRG.874.1;ENST00000372201;ENST00000465443;ENST00000476731;ENST00000492398;ENST00000461358;ENST00000461769;ENST00000493100	"GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000302(response to reactive oxygen species);GO:0000785(chromatin);GO:0002039(p53 binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005795(Golgi stack);GO:0005813(centrosome);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0006970(response to osmotic stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007093(mitotic cell cycle checkpoint);GO:0007113(endomitotic cell cycle);GO:0009314(response to radiation);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0030425(dendrite);GO:0031122(cytoplasmic microtubule organization);GO:0032465(regulation of cytokinesis);GO:0043025(neuronal cell body);GO:0043066(negative regulation of apoptotic process);GO:0043491(protein kinase B signaling);GO:0044819(mitotic G1/S transition checkpoint);GO:0051302(regulation of cell division);GO:0090166(Golgi disassembly);GO:0090316(positive regulation of intracellular protein transport);GO:2000777(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)"	05152(Tuberculosis)	NA	NA	polo-like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2154]	7.69	6.65	9.13	1.23	1.56	1.55	3.86	1.95	0	0.14	up	yes
MSTRG.8813	SPRED1	MSTRG.8813.1;MSTRG.8813.2;ENST00000299084;ENST00000561205	"GO:0000188(inactivation of MAPK activity);GO:0005173(stem cell factor receptor binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005901(caveola);GO:0007275(multicellular organismal development);GO:0009966(regulation of signal transduction);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010923(negative regulation of phosphatase activity);GO:0016020(membrane);GO:0019901(protein kinase binding);GO:0019902(phosphatase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0090311(regulation of protein deacetylation)"	04630(Jak-STAT signaling pathway)	NA	NA	"sprouty-related, EVH1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20249]"	4.08	5.12	4.55	14.47	11.63	8.71	0.37	-1.42	0	0.17	down	yes
MSTRG.8837	PAK6	ENST00000560120;ENST00000287598;ENST00000559414;ENST00000558715;ENST00000412359;ENST00000559461;ENST00000557848;ENST00000559772;ENST00000558972;ENST00000558151;ENST00000453867;ENST00000559435;ENST00000455577;ENST00000560346;ENST00000260404;ENST00000558878;ENST00000557926;ENST00000557808	"GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006915(apoptotic process);GO:0007010(cytoskeleton organization);GO:0007266(Rho protein signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0016477(cell migration);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0023014(signal transduction by protein phosphorylation);GO:0030036(actin cytoskeleton organization);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048365(Rac GTPase binding)"	04012(ErbB signaling pathway);04360(Axon guidance);04510(Focal adhesion);04660(T cell receptor signaling pathway);04810(Regulation of actin cytoskeleton);05211(Renal cell carcinoma)	NA	NA	p21 protein (Cdc42/Rac)-activated kinase 6 [Source:HGNC Symbol;Acc:HGNC:16061]	1.02	1.1	0.57	16.82	16.01	4.77	0.11	-3.14	0.02	0.27	down	yes
MSTRG.8845	KNSTRN	ENST00000559604;ENST00000416151;ENST00000560981;ENST00000249776;MSTRG.8845.2;ENST00000448395;ENST00000560321;ENST00000559591;ENST00000608100;ENST00000561196;ENST00000560220;ENST00000561169;ENST00000559304;ENST00000557920;ENST00000560673;ENST00000559083;ENST00000561367	GO:0000070(mitotic sister chromatid segregation);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0015630(microtubule cytoskeleton);GO:0035371(microtubule plus-end);GO:0051301(cell division);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0072686(mitotic spindle)	NA	NA	NA	kinetochore-localized astrin/SPAG5 binding protein [Source:HGNC Symbol;Acc:HGNC:30767]	5.84	7.8	5.55	20.81	22.01	8.69	0.33	-1.59	0.05	0.34	down	yes
MSTRG.8846	KNSTRN	MSTRG.8846.1	NA	NA	NA	NA	NA	0.29	0.64	0.68	4.52	4.51	1.42	0.28	-1.86	0.03	0.28	down	yes
MSTRG.8847	IVD	ENST00000610693;ENST00000487418;ENST00000479013;ENST00000558610;ENST00000473112;ENST00000484250;ENST00000481262;ENST00000491554;ENST00000497252;ENST00000560660;ENST00000497816;ENST00000559575;ENST00000466756	"GO:0003995(acyl-CoA dehydrogenase activity);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006552(leucine catabolic process);GO:0008152(metabolic process);GO:0008470(isovaleryl-CoA dehydrogenase activity);GO:0009083(branched-chain amino acid catabolic process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0031966(mitochondrial membrane);GO:0034641(cellular nitrogen compound metabolic process);GO:0044281(small molecule metabolic process);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process)"	"00280(Valine, leucine and isoleucine degradation);01100(Metabolic pathways)"	NA	NA	isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186]	1.09	1.77	2.23	3.55	4.3	4.41	0.49	-1.02	0.03	0.3	down	yes
MSTRG.8855	RPUSD2	ENST00000315616;ENST00000559271;ENST00000616318	GO:0001522(pseudouridine synthesis);GO:0003723(RNA binding);GO:0005575(cellular_component);GO:0008150(biological_process);GO:0009451(RNA modification);GO:0009982(pseudouridine synthase activity);GO:0044822(poly(A) RNA binding)	NA	NA	NA	RNA pseudouridylate synthase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24180]	0.61	1.83	1.72	6.67	3.74	3.79	0.3	-1.76	0	0.17	down	yes
MSTRG.8861	RAD51	ENST00000527860;ENST00000423169;ENST00000267868;ENST00000532743;ENST00000382643;ENST00000525066;ENST00000526763;ENST00000531277	GO:0000166(nucleotide binding);GO:0000228(nuclear chromosome);GO:0000724(double-strand break repair via homologous recombination);GO:0000730(DNA recombinase assembly);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0000800(lateral element);GO:0001932(regulation of protein phosphorylation);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003684(damaged DNA binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005815(microtubule organizing center);GO:0006259(DNA metabolic process);GO:0006268(DNA unwinding involved in DNA replication);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006310(DNA recombination);GO:0006312(mitotic recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007126(meiotic nuclear division);GO:0007127(meiosis I);GO:0007131(reciprocal meiotic recombination);GO:0008022(protein C-terminus binding);GO:0008094(DNA-dependent ATPase activity);GO:0009636(response to toxic substance);GO:0010165(response to X-ray);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0014070(response to organic cyclic compound);GO:0016605(PML body);GO:0031297(replication fork processing);GO:0032200(telomere organization);GO:0042493(response to drug);GO:0042802(identical protein binding);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0048471(perinuclear region of cytoplasm);GO:0051106(positive regulation of DNA ligation);GO:0051260(protein homooligomerization);GO:0070182(DNA polymerase binding);GO:0070192(chromosome organization involved in meiosis);GO:0071312(cellular response to alkaloid);GO:0071479(cellular response to ionizing radiation);GO:0071480(cellular response to gamma radiation);GO:0072711(cellular response to hydroxyurea);GO:0072719(cellular response to cisplatin);GO:0072757(cellular response to camptothecin);GO:1902521(response to etoposide);GO:1990414(replication-born double-strand break repair via sister chromatid exchange)	03440(Homologous recombination);05200(Pathways in cancer);05212(Pancreatic cancer)	NA	NA	RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817]	0.92	1.18	0.57	8.14	10.05	5.36	0.19	-2.36	0.01	0.2	down	yes
MSTRG.8879	OIP5	ENST00000220514;ENST00000560640	"GO:0000775(chromosome, centromeric region);GO:0000785(chromatin);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006334(nucleosome assembly);GO:0007067(mitotic nuclear division);GO:0007154(cell communication);GO:0010369(chromocenter);GO:0015030(Cajal body);GO:0034080(CENP-A containing nucleosome assembly);GO:0051301(cell division)"	NA	NA	NA	Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300]	0.98	2.07	0.57	15.16	15.62	5.72	0.12	-3.01	0.01	0.24	down	yes
MSTRG.8880	NUSAP1	ENST00000558123;ENST00000260359;ENST00000559046;MSTRG.8880.3;MSTRG.8880.5;ENST00000450592;ENST00000559596;ENST00000414849;ENST00000558582;ENST00000560747;ENST00000559659;ENST00000560177;ENST00000557840;ENST00000560898;ENST00000560318	GO:0000070(mitotic sister chromatid segregation);GO:0000281(mitotic cytokinesis);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005874(microtubule);GO:0005876(spindle microtubule);GO:0007076(mitotic chromosome condensation);GO:0008017(microtubule binding);GO:0040001(establishment of mitotic spindle localization);GO:0044822(poly(A) RNA binding);GO:0045840(positive regulation of mitotic nuclear division)	NA	NA	NA	nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538]	4.33	5.49	1.99	72.05	50.99	13.43	0.08	-3.65	0.03	0.29	down	yes
MSTRG.8930	LCMT2	ENST00000305641;ENST00000567039	GO:0005515(protein binding);GO:0008033(tRNA processing);GO:0008168(methyltransferase activity);GO:0032259(methylation)	00340(Histidine metabolism);00350(Tyrosine metabolism)	NA	NA	leucine carboxyl methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:17558]	0	0.18	0	5.74	6.37	3.61	0.15	-2.73	0	0.15	down	yes
MSTRG.895	TOE1	MSTRG.895.1;MSTRG.895.2;MSTRG.895.3;ENST00000372090;ENST00000477731;ENST00000471337;ENST00000495703;ENST00000460057	GO:0003676(nucleic acid binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0016607(nuclear speck);GO:0046872(metal ion binding)	NA	NA	NA	"target of EGR1, member 1 (nuclear) [Source:HGNC Symbol;Acc:HGNC:15954]"	3	3.24	3.88	11.57	12.93	6.28	0.35	-1.53	0.03	0.28	down	yes
MSTRG.8955	WDR76	ENST00000263795;ENST00000381246;ENST00000452115;ENST00000478130	GO:0005515(protein binding)	NA	NA	NA	WD repeat domain 76 [Source:HGNC Symbol;Acc:HGNC:25773]	1.6	2.23	1.46	9.05	9.79	5.48	0.26	-1.94	0.01	0.2	down	yes
MSTRG.898	NASP	MSTRG.898.1;ENST00000537798;ENST00000437362;ENST00000464190;ENST00000528084;ENST00000527359;ENST00000530840;ENST00000531532;ENST00000529333;ENST00000527470;ENST00000525515;ENST00000453748;ENST00000528238;ENST00000534101;ENST00000350030;ENST00000470768;ENST00000372052;ENST00000351223;ENST00000530073;ENST00000481782;ENST00000531612;ENST00000527932;ENST00000534450;ENST00000472408	GO:0000790(nuclear chromatin);GO:0001824(blastocyst development);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006334(nucleosome assembly);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007049(cell cycle);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0015031(protein transport);GO:0032403(protein complex binding);GO:0033574(response to testosterone);GO:0042393(histone binding);GO:0043234(protein complex);GO:0043486(histone exchange);GO:0051879(Hsp90 protein binding)	NA	NA	NA	nuclear autoantigenic sperm protein (histone-binding) [Source:HGNC Symbol;Acc:HGNC:7644]	9.24	9.01	7.18	31.38	27.02	15.57	0.33	-1.6	0.03	0.28	down	yes
MSTRG.9010	DUT	ENST00000559935;ENST00000559416;ENST00000558813;ENST00000331200;ENST00000558472;ENST00000558978;ENST00000455976;ENST00000559540;ENST00000558367;ENST00000561350;ENST00000559852	GO:0000287(magnesium ion binding);GO:0004170(dUTP diphosphatase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0006139(nucleobase-containing compound metabolic process);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006226(dUMP biosynthetic process);GO:0006260(DNA replication);GO:0016787(hydrolase activity);GO:0044281(small molecule metabolic process);GO:0044822(poly(A) RNA binding);GO:0046080(dUTP metabolic process);GO:0046081(dUTP catabolic process);GO:0046134(pyrimidine nucleoside biosynthetic process);GO:0055086(nucleobase-containing small molecule metabolic process);GO:0070062(extracellular exosome)	00240(Pyrimidine metabolism);01100(Metabolic pathways)	NA	NA	deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078]	6.22	6.47	6.55	24.34	27.52	19.21	0.29	-1.81	0	0.17	down	yes
MSTRG.9020	EID1	ENST00000530028	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0007049(cell cycle);GO:0016235(aggresome);GO:0030154(cell differentiation);GO:0035034(histone acetyltransferase regulator activity);GO:0035035(histone acetyltransferase binding);GO:0035065(regulation of histone acetylation);GO:0045892(negative regulation of transcription, DNA-templated)"	NA	NA	NA	EP300 interacting inhibitor of differentiation 1 [Source:HGNC Symbol;Acc:HGNC:1191]	30.78	41.24	52.14	154.05	132.02	71.85	0.27	-1.89	0.02	0.25	down	yes
MSTRG.908	PIK3R3	ENST00000262741;ENST00000372006;ENST00000420542;ENST00000488808;ENST00000540385;ENST00000423209;ENST00000493202;ENST00000425892	GO:0005515(protein binding);GO:0005829(cytosol);GO:0005942(phosphatidylinositol 3-kinase complex);GO:0006644(phospholipid metabolic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0008286(insulin receptor signaling pathway);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0043551(regulation of phosphatidylinositol 3-kinase activity);GO:0044281(small molecule metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0046935(1-phosphatidylinositol-3-kinase regulator activity);GO:2001275(positive regulation of glucose import in response to insulin stimulus)	04012(ErbB signaling pathway);04062(Chemokine signaling pathway);04070(Phosphatidylinositol signaling system);04150(mTOR signaling pathway);04210(Apoptosis);04370(VEGF signaling pathway);04380(Osteoclast differentiation);04510(Focal adhesion);04620(Toll-like receptor signaling pathway);04630(Jak-STAT signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04722(Neurotrophin signaling pathway);04725(Cholinergic synapse);04810(Regulation of actin cytoskeleton);04910(Insulin signaling pathway);04914(Progesterone-mediated oocyte maturation);04930(Type II diabetes mellitus);04960(Aldosterone-regulated sodium reabsorption);04973(Carbohydrate digestion and absorption);05100(Bacterial invasion of epithelial cells);05142(Chagas disease (American trypanosomiasis));05145(Toxoplasmosis);05146(Amoebiasis);05160(Hepatitis C);05162(Measles);05164(Influenza A);05200(Pathways in cancer);05210(Colorectal cancer);05211(Renal cell carcinoma);05212(Pancreatic cancer);05213(Endometrial cancer);05214(Glioma);05215(Prostate cancer);05218(Melanoma);05220(Chronic myeloid leukemia);05221(Acute myeloid leukemia);05222(Small cell lung cancer);05223(Non-small cell lung cancer)	NA	NA	"phosphoinositide-3-kinase, regulatory subunit 3 (gamma) [Source:HGNC Symbol;Acc:HGNC:8981]"	0.63	0.78	1.25	4.47	3.78	2.83	0.35	-1.51	0.01	0.2	down	yes
MSTRG.9095	RSL24D1	ENST00000260443;ENST00000562993;ENST00000564344;ENST00000569386;ENST00000565854;ENST00000562895	GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005840(ribosome);GO:0006412(translation);GO:0042254(ribosome biogenesis)	NA	NA	NA	ribosomal L24 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18479]	93.81	100.47	74.26	23.26	39.45	33.37	3.05	1.61	0.02	0.26	up	yes
MSTRG.9099	DYX1C1	ENST00000564663;ENST00000563294;MSTRG.9099.3;ENST00000442196;ENST00000565113;ENST00000310958;ENST00000425574;ENST00000568543;ENST00000568592;ENST00000568372;ENST00000568808;ENST00000569205;ENST00000563171;ENST00000570272;ENST00000564092;ENST00000524160;ENST00000448430;ENST00000457155;ENST00000348518;ENST00000321149;MSTRG.9099.23;ENST00000522437;ENST00000519017	GO:0001764(neuron migration);GO:0003341(cilium movement);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0007368(determination of left/right symmetry);GO:0030331(estrogen receptor binding);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0036158(outer dynein arm assembly);GO:0036159(inner dynein arm assembly);GO:0061136(regulation of proteasomal protein catabolic process)	NA	NA	NA	dyslexia susceptibility 1 candidate 1 [Source:HGNC Symbol;Acc:HGNC:21493]	18.13	21.74	17	2.94	3.21	1.51	4.91	2.3	0	0.18	up	yes
MSTRG.9153	CCNB2	ENST00000288207;MSTRG.9153.1;ENST00000561077;ENST00000559622;ENST00000621385;ENST00000559301	GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0001701(in utero embryonic development);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005829(cytosol);GO:0007067(mitotic nuclear division);GO:0007077(mitotic nuclear envelope disassembly);GO:0015630(microtubule cytoskeleton);GO:0016020(membrane);GO:0040007(growth);GO:0043029(T cell homeostasis);GO:0048538(thymus development);GO:0051301(cell division);GO:0051726(regulation of cell cycle)	04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04914(Progesterone-mediated oocyte maturation)	NA	NA	cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580]	8.01	6.07	2.99	47.42	50.38	21.12	0.16	-2.69	0.04	0.31	down	yes
MSTRG.917	NSUN4	ENST00000474844;MSTRG.917.2;ENST00000307089;ENST00000486270;ENST00000469918;ENST00000472157;ENST00000537428;ENST00000498008;ENST00000495427;ENST00000475281	GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0008168(methyltransferase activity);GO:0031167(rRNA methylation);GO:0042256(mature ribosome assembly);GO:0070131(positive regulation of mitochondrial translation);GO:0070181(small ribosomal subunit rRNA binding)	NA	NA	NA	"NOP2/Sun domain family, member 4 [Source:HGNC Symbol;Acc:HGNC:31802]"	4.33	3.76	4.21	1.68	1.54	1.75	2	1	0	0.12	up	yes
MSTRG.9172	RP11-361D15.2	MSTRG.9172.1;ENST00000560199	NA	NA	NA	NA	NA	8.25	3.42	1.95	0.02	0.23	0.16	6	2.58	0.02	0.26	up	yes
MSTRG.919	RAD54L	ENST00000463715;ENST00000493985;MSTRG.919.3;ENST00000371975;ENST00000469835;ENST00000487700;ENST00000472889;ENST00000473251;ENST00000476687;ENST00000488942;ENST00000459678	"GO:0000724(double-strand break repair via homologous recombination);GO:0000733(DNA strand renaturation);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006302(double-strand break repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007126(meiotic nuclear division);GO:0008152(metabolic process);GO:0008340(determination of adult lifespan);GO:0010212(response to ionizing radiation);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0036310(annealing helicase activity);GO:0042493(response to drug);GO:0051276(chromosome organization)"	03440(Homologous recombination)	NA	NA	RAD54-like (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:9826]	1.51	1.45	0.73	13.45	11.71	8.34	0.17	-2.57	0.01	0.19	down	yes
MSTRG.9203	LACTB	ENST00000261893;MSTRG.9203.2;ENST00000413507;ENST00000557972;ENST00000559782	GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0016787(hydrolase activity)	NA	NA	NA	"lactamase, beta [Source:HGNC Symbol;Acc:HGNC:16468]"	10.77	9.77	8.64	3.17	3.38	2.67	2.66	1.41	0	0.17	up	yes
MSTRG.9207	USP3	ENST00000540797;MSTRG.9207.2;ENST00000561442;ENST00000380324;ENST00000557884;ENST00000558157;ENST00000561326;ENST00000559873;ENST00000559192;ENST00000559276;ENST00000268049;ENST00000558285;ENST00000538686;ENST00000559711;ENST00000558925;ENST00000558218;ENST00000561381;ENST00000559718;ENST00000560202	"GO:0000278(mitotic cell cycle);GO:0000790(nuclear chromatin);GO:0004197(cysteine-type endopeptidase activity);GO:0004843(ubiquitin-specific protease activity);GO:0005634(nucleus);GO:0006281(DNA repair);GO:0006355(regulation of transcription, DNA-templated);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008270(zinc ion binding);GO:0016578(histone deubiquitination);GO:0031647(regulation of protein stability);GO:0036459(ubiquitinyl hydrolase activity);GO:0042393(histone binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0061136(regulation of proteasomal protein catabolic process)"	NA	NA	NA	ubiquitin specific peptidase 3 [Source:HGNC Symbol;Acc:HGNC:12626]	11.36	10.91	9.11	3.04	3.28	4.06	2.78	1.47	0	0.17	up	yes
MSTRG.9213	SNX1	ENST00000560829;ENST00000559061;ENST00000380285;ENST00000261889;ENST00000559844;MSTRG.9213.5;ENST00000560260;ENST00000625244;ENST00000561026;MSTRG.9213.8;ENST00000558040;ENST00000559389;ENST00000559401;ENST00000559339;ENST00000559961;ENST00000560861	"GO:0005154(epidermal growth factor receptor binding);GO:0005158(insulin receptor binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0010008(endosome membrane);GO:0016020(membrane);GO:0016050(vesicle organization);GO:0016197(endosomal transport);GO:0019898(extrinsic component of membrane);GO:0030027(lamellipodium);GO:0030904(retromer complex);GO:0031623(receptor internalization);GO:0031901(early endosome membrane);GO:0034498(early endosome to Golgi transport);GO:0035091(phosphatidylinositol binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0045732(positive regulation of protein catabolic process);GO:0072673(lamellipodium morphogenesis);GO:1990459(transferrin receptor binding);GO:1990460(leptin receptor binding)"	NA	NA	NA	sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172]	6.04	8.26	8.4	20.96	18.15	36.14	0.35	-1.53	0.05	0.33	down	yes
MSTRG.9235	PIF1	MSTRG.9235.1;ENST00000268043;ENST00000559239;ENST00000559872;ENST00000559522;ENST00000558380;ENST00000558547;ENST00000560444;ENST00000560504	"GO:0000002(mitochondrial genome maintenance);GO:0000287(magnesium ion binding);GO:0000723(telomere maintenance);GO:0000784(nuclear chromosome, telomeric region);GO:0003678(DNA helicase activity);GO:0004386(helicase activity);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0010521(telomerase inhibitor activity);GO:0017116(single-stranded DNA-dependent ATP-dependent DNA helicase activity);GO:0032204(regulation of telomere maintenance);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0032508(DNA duplex unwinding);GO:0033682(ATP-dependent 5'-3' DNA/RNA helicase activity);GO:0042162(telomeric DNA binding);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0051880(G-quadruplex DNA binding);GO:0051974(negative regulation of telomerase activity)"	NA	NA	NA	PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220]	0.45	0.26	0.17	4.12	4.71	2.05	0.27	-1.88	0.02	0.26	down	yes
MSTRG.9277	RPL4	ENST00000307961;ENST00000567229;ENST00000565723;ENST00000568588;ENST00000561775;ENST00000569696;ENST00000564744;ENST00000564647;ENST00000563473;ENST00000566039;ENST00000564439;ENST00000566622;ENST00000569438;ENST00000566624;ENST00000561554;ENST00000566491	"GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006412(translation);GO:0006413(translational initiation);GO:0006414(translational elongation);GO:0006415(translational termination);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010467(gene expression);GO:0016020(membrane);GO:0016032(viral process);GO:0019058(viral life cycle);GO:0019083(viral transcription);GO:0022625(cytosolic large ribosomal subunit);GO:0030529(ribonucleoprotein complex);GO:0044267(cellular protein metabolic process);GO:0044822(poly(A) RNA binding);GO:0070062(extracellular exosome)"	NA	NA	NA	ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:10353]	656.88	655.54	618.42	306.02	287.18	481.92	2.05	1.03	0.04	0.33	up	yes
MSTRG.9279	LCTL	MSTRG.9279.1;ENST00000341509;ENST00000537670;ENST00000565875;ENST00000563438;ENST00000562179	"GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005903(brush border);GO:0005975(carbohydrate metabolic process);GO:0016021(integral component of membrane)"	NA	NA	NA	lactase-like [Source:HGNC Symbol;Acc:HGNC:15583]	0.3	0.42	0.24	2.19	2.14	0.68	0.43	-1.21	0.05	0.34	down	yes
MSTRG.93	C1orf233	ENST00000422725	GO:0016021(integral component of membrane)	NA	NA	NA	chromosome 1 open reading frame 233 [Source:HGNC Symbol;Acc:HGNC:42951]	1	1.07	1.05	3.23	3.95	4.42	0.45	-1.17	0	0.17	down	yes
MSTRG.9329	LARP6	ENST00000299213;ENST00000559316;ENST00000560052;ENST00000344870;ENST00000559140	GO:0000166(nucleotide binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0006417(regulation of translation);GO:0030529(ribonucleoprotein complex)	NA	NA	NA	"La ribonucleoprotein domain family, member 6 [Source:HGNC Symbol;Acc:HGNC:24012]"	35.59	35.07	28.23	3.35	3.29	6.25	7.51	2.91	0	0.17	up	yes
MSTRG.9331	LRRC49	MSTRG.9331.1;ENST00000544974;MSTRG.9331.2;MSTRG.9331.4;MSTRG.9331.5;ENST00000558799;ENST00000558546;ENST00000561081;ENST00000443425;ENST00000559201;MSTRG.9331.11;ENST00000560107;ENST00000560369;ENST00000260382;ENST00000559670;ENST00000558032;ENST00000560755;ENST00000560980;ENST00000558204;ENST00000557977;ENST00000560691;ENST00000558271;ENST00000558137;ENST00000561285;ENST00000559469;ENST00000560158;ENST00000559685;ENST00000559422;ENST00000561131	GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005874(microtubule)	NA	NA	NA	leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965]	5.85	6.11	7.52	0.76	0.66	0.23	4.39	2.14	0	0.17	up	yes
MSTRG.9346	PKM	MSTRG.9346.1;ENST00000564440;ENST00000319622;ENST00000389093;ENST00000449901;ENST00000565184;ENST00000335181;ENST00000568883;ENST00000565143;ENST00000567118;ENST00000565154;ENST00000568459;ENST00000561609;ENST00000563986;ENST00000569857;ENST00000570166;ENST00000564993;ENST00000563275;ENST00000568743;ENST00000562784;ENST00000564178;ENST00000562997;ENST00000567087;ENST00000564276;ENST00000566809;ENST00000569050	GO:0000287(magnesium ion binding);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0003824(catalytic activity);GO:0004743(pyruvate kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0005975(carbohydrate metabolic process);GO:0006006(glucose metabolic process);GO:0006096(glycolytic process);GO:0006754(ATP biosynthetic process);GO:0007584(response to nutrient);GO:0009629(response to gravity);GO:0010033(response to organic substance);GO:0012501(programmed cell death);GO:0014870(response to muscle inactivity);GO:0016310(phosphorylation);GO:0023026(MHC class II protein complex binding);GO:0030955(potassium ion binding);GO:0031012(extracellular matrix);GO:0031100(organ regeneration);GO:0031982(vesicle);GO:0032868(response to insulin);GO:0042866(pyruvate biosynthetic process);GO:0043209(myelin sheath);GO:0043403(skeletal muscle tissue regeneration);GO:0043531(ADP binding);GO:0044281(small molecule metabolic process);GO:0044822(poly(A) RNA binding);GO:0061621(canonical glycolysis);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)	00010(Glycolysis / Gluconeogenesis);00230(Purine metabolism);00620(Pyruvate metabolism);01100(Metabolic pathways);04930(Type II diabetes mellitus)	K00873;K12406	2.7.1.40	"pyruvate kinase, muscle [Source:HGNC Symbol;Acc:HGNC:9021]"	147.13	129.83	141.97	325.92	322.58	312.33	0.45	-1.15	0	0.11	down	yes
MSTRG.9372	UBL7-AS1	MSTRG.9372.1;ENST00000499217;MSTRG.9372.4;ENST00000567286;ENST00000564621	NA	NA	NA	NA	NA	0.67	1.3	1.32	3.89	4.15	3.29	0.38	-1.41	0	0.17	down	yes
MSTRG.9390	SCAMP5	ENST00000425597;ENST00000562327;ENST00000568018;MSTRG.9390.5;MSTRG.9390.6;ENST00000562212;ENST00000565923;ENST00000562765;ENST00000567535;ENST00000564491;ENST00000361900;ENST00000568119;MSTRG.9390.18;ENST00000567529;ENST00000568081	GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0006887(exocytosis);GO:0015031(protein transport);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0030672(synaptic vesicle membrane);GO:0031201(SNARE complex);GO:0032588(trans-Golgi network membrane);GO:0034976(response to endoplasmic reticulum stress);GO:0045806(negative regulation of endocytosis);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0055038(recycling endosome membrane)	NA	NA	NA	secretory carrier membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:30386]	0.23	1.54	0.97	2.35	2.76	2.68	0.4	-1.34	0.03	0.28	down	yes
MSTRG.9398	COMMD4	ENST00000267935;ENST00000567195;ENST00000566843;ENST00000564815;ENST00000562610;ENST00000338995;ENST00000567023;ENST00000567720;ENST00000566230;ENST00000564587;ENST00000564068;ENST00000480484;ENST00000567399;ENST00000561662;ENST00000562789;ENST00000568301;ENST00000568877;ENST00000565834;ENST00000563220;ENST00000569245;ENST00000562310	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)"	NA	NA	NA	COMM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26027]	2.16	1.89	2.53	12.44	13.07	8.45	0.25	-2.01	0.01	0.19	down	yes
MSTRG.9458	IREB2	ENST00000560840;ENST00000559215;ENST00000258886;ENST00000558525;ENST00000560440;ENST00000558570;ENST00000560454;ENST00000559427;ENST00000559676;ENST00000559091	"GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0008152(metabolic process);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0017148(negative regulation of translation);GO:0030316(osteoclast differentiation);GO:0030350(iron-responsive element binding);GO:0030371(translation repressor activity);GO:0034101(erythrocyte homeostasis);GO:0046872(metal ion binding);GO:0050892(intestinal absorption);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0055072(iron ion homeostasis)"	NA	K01702	4.2.1.33	iron-responsive element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6115]	2.36	3.71	3.22	8.47	6.75	3.01	0.44	-1.19	0.04	0.33	down	yes
MSTRG.9462	WDR61	MSTRG.9462.1;ENST00000560807;MSTRG.9462.2;ENST00000558412;ENST00000559332;ENST00000559940;ENST00000558311;MSTRG.9462.7;ENST00000267973;ENST00000558459;ENST00000560569;ENST00000560610;ENST00000559848;ENST00000560063;ENST00000559700;ENST00000558840;ENST00000560946;ENST00000561347	"GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0016593(Cdc73/Paf1 complex);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0034427(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5');GO:0035327(transcriptionally active chromatin);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0055087(Ski complex);GO:0080182(histone H3-K4 trimethylation);GO:2001162(positive regulation of histone H3-K79 methylation)"	03018(RNA degradation)	NA	NA	WD repeat domain 61 [Source:HGNC Symbol;Acc:HGNC:30300]	3.4	4.09	6.98	11.48	11.28	10.42	0.43	-1.23	0.04	0.32	down	yes
MSTRG.9501	LINC01583	ENST00000558082;MSTRG.9501.1;MSTRG.9501.5	NA	NA	NA	NA	NA	6.58	5.47	8.05	0.67	0.52	0.13	5.09	2.35	0	0.19	up	yes
MSTRG.9511	GOLGA6L9	MSTRG.9511.1;MSTRG.9511.2;MSTRG.9511.3;MSTRG.9511.5;MSTRG.9511.4;MSTRG.9511.6;ENST00000618775;ENST00000613592;ENST00000561287;ENST00000558542;MSTRG.9511.11;ENST00000613086;ENST00000558668;ENST00000618348;ENST00000618706	NA	NA	NA	NA	golgin A6 family-like 9 [Source:HGNC Symbol;Acc:HGNC:37229]	3.71	4.95	3.38	1.11	1.23	1.07	2.16	1.11	0.01	0.2	up	yes
MSTRG.9569	NMB	ENST00000360476;ENST00000394588;MSTRG.9569.1	NA	NA	NA	NA	NA	8.94	6.46	5.49	18.25	14.27	19.24	0.48	-1.05	0.03	0.3	down	yes
MSTRG.9600	ISG20	ENST00000560741;ENST00000558992;ENST00000306072;ENST00000559876;ENST00000558942;ENST00000560573;ENST00000557824;ENST00000546338	"GO:0000175(3'-5'-exoribonuclease activity);GO:0000738(DNA catabolic process, exonucleolytic);GO:0003676(nucleic acid binding);GO:0004527(exonuclease activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006364(rRNA processing);GO:0006401(RNA catabolic process);GO:0008283(cell proliferation);GO:0008310(single-stranded DNA 3'-5' exodeoxyribonuclease activity);GO:0008859(exoribonuclease II activity);GO:0009615(response to virus);GO:0015030(Cajal body);GO:0016605(PML body);GO:0019221(cytokine-mediated signaling pathway);GO:0030619(U1 snRNA binding);GO:0030620(U2 snRNA binding);GO:0034511(U3 snoRNA binding);GO:0045071(negative regulation of viral genome replication);GO:0046872(metal ion binding);GO:0051607(defense response to virus);GO:0060337(type I interferon signaling pathway);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)"	NA	NA	NA	interferon stimulated exonuclease gene 20kDa [Source:HGNC Symbol;Acc:HGNC:6130]	2.06	1.66	2.11	0.39	0.29	0.88	2.19	1.13	0.01	0.24	up	yes
MSTRG.9611	FANCI	MSTRG.9611.2;MSTRG.9611.3;MSTRG.9611.1;MSTRG.9611.8;MSTRG.9611.9;MSTRG.9611.4;MSTRG.9611.7;MSTRG.9611.5;MSTRG.9611.6;ENST00000300027;MSTRG.9611.15;MSTRG.9611.11;MSTRG.9611.12;MSTRG.9611.13;MSTRG.9611.14;ENST00000310775;ENST00000568670;ENST00000567891;ENST00000564920;ENST00000565255;ENST00000447611;ENST00000570110;ENST00000567996;ENST00000563250;MSTRG.9611.25;ENST00000564636;ENST00000570225;ENST00000561894;ENST00000566895;ENST00000564350;ENST00000566615	GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0007049(cell cycle);GO:0016020(membrane);GO:0031398(positive regulation of protein ubiquitination);GO:0070182(DNA polymerase binding)	NA	NA	NA	"Fanconi anemia, complementation group I [Source:HGNC Symbol;Acc:HGNC:25568]"	3.16	3.75	2.36	21.74	18.64	6.83	0.2	-2.33	0.03	0.29	down	yes
MSTRG.9618	TICRR	MSTRG.9618.2;MSTRG.9618.1;ENST00000268138;ENST00000560985;ENST00000561095	GO:0000075(cell cycle checkpoint);GO:0001731(formation of translation preinitiation complex);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0010212(response to ionizing radiation);GO:0030174(regulation of DNA-dependent DNA replication initiation);GO:0033314(mitotic DNA replication checkpoint)	NA	NA	NA	TOPBP1-interacting checkpoint and replication regulator [Source:HGNC Symbol;Acc:HGNC:28704]	0.38	0.32	0.26	5.02	3.75	2.44	0.25	-1.99	0.01	0.2	down	yes
MSTRG.9660	BLM	ENST00000355112;ENST00000559724;MSTRG.9660.4;ENST00000559282;ENST00000559426;ENST00000560136;ENST00000560559;ENST00000558825;ENST00000560821	"GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000166(nucleotide binding);GO:0000228(nuclear chromosome);GO:0000405(bubble DNA binding);GO:0000724(double-strand break repair via homologous recombination);GO:0000729(DNA double-strand break processing);GO:0000733(DNA strand renaturation);GO:0000781(chromosome, telomeric region);GO:0000800(lateral element);GO:0002039(p53 binding);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003697(single-stranded DNA binding);GO:0003824(catalytic activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0008026(ATP-dependent helicase activity);GO:0009378(four-way junction helicase activity);GO:0010165(response to X-ray);GO:0016363(nuclear matrix);GO:0016605(PML body);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0016887(ATPase activity);GO:0016925(protein sumoylation);GO:0031297(replication fork processing);GO:0032508(DNA duplex unwinding);GO:0036310(annealing helicase activity);GO:0043140(ATP-dependent 3'-5' DNA helicase activity);GO:0043687(post-translational protein modification);GO:0044237(cellular metabolic process);GO:0044267(cellular protein metabolic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045910(negative regulation of DNA recombination);GO:0048478(replication fork protection);GO:0051259(protein oligomerization);GO:0051782(negative regulation of cell division);GO:0051880(G-quadruplex DNA binding);GO:0071479(cellular response to ionizing radiation);GO:0072711(cellular response to hydroxyurea);GO:0072757(cellular response to camptothecin)"	03440(Homologous recombination)	NA	NA	"Bloom syndrome, RecQ helicase-like [Source:HGNC Symbol;Acc:HGNC:1058]"	0.39	0.45	0.17	4.97	3.78	0.98	0.26	-1.93	0.05	0.34	down	yes
MSTRG.9667	PRC1	MSTRG.9667.1;MSTRG.9667.2;ENST00000394249;MSTRG.9667.4;MSTRG.9667.3;MSTRG.9667.9;MSTRG.9667.7;MSTRG.9667.8;MSTRG.9667.6;ENST00000556972;ENST00000361188;ENST00000555455;ENST00000560423;ENST00000442656;ENST00000559828;ENST00000559326;ENST00000560914;ENST00000556982;ENST00000553494;ENST00000557763;ENST00000417173;ENST00000560605;ENST00000557905;ENST00000555791;ENST00000555745;ENST00000559811;ENST00000556129	GO:0000022(mitotic spindle elongation);GO:0000226(microtubule cytoskeleton organization);GO:0000910(cytokinesis);GO:0000922(spindle pole);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005819(spindle);GO:0005829(cytosol);GO:0005876(spindle microtubule);GO:0005886(plasma membrane);GO:0007264(small GTPase mediated signal transduction);GO:0008017(microtubule binding);GO:0015630(microtubule cytoskeleton);GO:0019894(kinesin binding);GO:0019901(protein kinase binding);GO:0042802(identical protein binding)	NA	NA	NA	protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341]	7.57	6.98	4.77	75.78	81.31	23.43	0.11	-3.2	0.03	0.28	down	yes
MSTRG.9680	CHD2	MSTRG.9680.1;ENST00000557682;ENST00000553829;ENST00000556895;ENST00000554669;ENST00000554894;ENST00000557147;ENST00000629685;ENST00000554133;ENST00000555227;ENST00000630790;ENST00000555520;ENST00000626874;MSTRG.9680.14;ENST00000394196;ENST00000627622;ENST00000629346;ENST00000628375;ENST00000420239;ENST00000625990;ENST00000626782;ENST00000629136;ENST00000625243;ENST00000630016;ENST00000627200;ENST00000628118;MSTRG.9680.30;ENST00000627185;ENST00000625662;ENST00000629104;ENST00000630813;ENST00000627460	"GO:0001046(core promoter sequence-specific DNA binding);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006974(cellular response to DNA damage stimulus);GO:0007517(muscle organ development);GO:0008152(metabolic process);GO:0016568(chromatin modification);GO:0032508(DNA duplex unwinding);GO:0042393(histone binding);GO:0043231(intracellular membrane-bounded organelle);GO:0044822(poly(A) RNA binding);GO:0060218(hematopoietic stem cell differentiation);GO:0070062(extracellular exosome)"	NA	NA	NA	chromodomain helicase DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1917]	8.9	10.58	9.26	3.91	3.36	2.63	2.18	1.12	0	0.15	up	yes
MSTRG.9703	SYNM	ENST00000560674;ENST00000336292;ENST00000328642;ENST00000594047	GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005912(adherens junction);GO:0008307(structural constituent of muscle);GO:0016020(membrane);GO:0017166(vinculin binding);GO:0019215(intermediate filament binding);GO:0043034(costamere);GO:0045104(intermediate filament cytoskeleton organization);GO:0060053(neurofilament cytoskeleton)	NA	NA	NA	"synemin, intermediate filament protein [Source:HGNC Symbol;Acc:HGNC:24466]"	5	11.96	6.7	29.78	27.17	18	0.23	-2.14	0	0.16	down	yes
MSTRG.9738	VIMP	ENST00000398226;ENST00000531964;ENST00000526049;ENST00000526043;ENST00000527833;ENST00000529968;ENST00000534014	"GO:0002865(negative regulation of acute inflammatory response to antigenic stimulus);GO:0004872(receptor activity);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005881(cytoplasmic microtubule);GO:0005886(plasma membrane);GO:0006111(regulation of gluconeogenesis);GO:0006886(intracellular protein transport);GO:0006983(ER overload response);GO:0008430(selenium binding);GO:0009749(response to glucose);GO:0016209(antioxidant activity);GO:0019899(enzyme binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030433(ER-associated ubiquitin-dependent protein catabolic process);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030970(retrograde protein transport, ER to cytosol);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032869(cellular response to insulin stimulus);GO:0034361(very-low-density lipoprotein particle);GO:0034362(low-density lipoprotein particle);GO:0034599(cellular response to oxidative stress);GO:0045184(establishment of protein localization);GO:0045454(cell redox homeostasis);GO:0045719(negative regulation of glycogen biosynthetic process);GO:0046325(negative regulation of glucose import);GO:0050728(negative regulation of inflammatory response);GO:0051117(ATPase binding);GO:0051771(negative regulation of nitric-oxide synthase biosynthetic process);GO:0051775(response to redox state);GO:0071222(cellular response to lipopolysaccharide);GO:0080164(regulation of nitric oxide metabolic process);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1990381(ubiquitin-specific protease binding);GO:2000110(negative regulation of macrophage apoptotic process)"	04141(Protein processing in endoplasmic reticulum)	NA	NA	VCP-interacting membrane selenoprotein [Source:HGNC Symbol;Acc:HGNC:30396]	22.38	25.1	25.81	9.04	11.01	6.5	2.38	1.25	0.02	0.26	up	yes
MSTRG.9766	SNRNP25	ENST00000293861;ENST00000383018;ENST00000397876;ENST00000466183;ENST00000481947	GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005689(U12-type spliceosomal complex);GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0045171(intercellular bridge)	NA	NA	NA	small nuclear ribonucleoprotein 25kDa (U11/U12) [Source:HGNC Symbol;Acc:HGNC:14161]	0.86	0.73	0.48	2.15	4.05	2.66	0.48	-1.07	0.04	0.31	down	yes
MSTRG.9849	FAHD1	ENST00000427358;ENST00000382666;ENST00000615972	GO:0003824(catalytic activity);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005829(cytosol);GO:0008152(metabolic process);GO:0008948(oxaloacetate decarboxylase activity);GO:0018773(acetylpyruvate hydrolase activity);GO:0034545(fumarylpyruvate hydrolase activity);GO:0046872(metal ion binding);GO:0047621(acylpyruvate hydrolase activity)	NA	NA	NA	fumarylacetoacetate hydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14169]	2.34	3.1	4	7.43	7.7	4.88	0.46	-1.12	0.03	0.28	down	yes
MSTRG.9864	IGFALS	ENST00000566339;ENST00000564709;MSTRG.9864.3;MSTRG.9864.4;ENST00000569380;ENST00000567868;ENST00000563741;ENST00000563668;ENST00000563705;ENST00000569769;ENST00000565550;ENST00000564070;ENST00000568416;ENST00000215539;ENST00000415638;ENST00000568221	GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0007165(signal transduction);GO:0042567(insulin-like growth factor ternary complex);GO:0044267(cellular protein metabolic process);GO:0070062(extracellular exosome)	NA	NA	NA	"insulin-like growth factor binding protein, acid labile subunit [Source:HGNC Symbol;Acc:HGNC:5468]"	5.15	5.07	4.48	1.37	1	3.04	2.49	1.32	0.05	0.34	up	yes
MSTRG.9875	ZNF598	MSTRG.9875.2;ENST00000562988;MSTRG.9875.1;ENST00000563630;MSTRG.9875.6;MSTRG.9875.5;ENST00000565396;ENST00000431526;MSTRG.9875.9;ENST00000567008;ENST00000562103;ENST00000564556;MSTRG.9875.12;ENST00000564824;ENST00000561787;ENST00000567625	GO:0005515(protein binding);GO:0008270(zinc ion binding);GO:0044822(poly(A) RNA binding);GO:0046872(metal ion binding)	NA	NA	NA	zinc finger protein 598 [Source:HGNC Symbol;Acc:HGNC:28079]	15.01	14.81	18.01	5.91	6.81	6	2.35	1.23	0	0.17	up	yes
MSTRG.9879	SLC9A3R2	ENST00000567504;ENST00000424542;ENST00000432365;MSTRG.9879.4;MSTRG.9879.5;ENST00000563587;ENST00000561844;MSTRG.9879.8;ENST00000565086;ENST00000565855;ENST00000566198;ENST00000564033	GO:0005102(receptor binding);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006461(protein complex assembly);GO:0008013(beta-catenin binding);GO:0008022(protein C-terminus binding);GO:0012505(endomembrane system);GO:0016247(channel regulator activity);GO:0016324(apical plasma membrane);GO:0019902(phosphatase binding);GO:0030165(PDZ domain binding);GO:0032947(protein complex scaffold);GO:0043234(protein complex);GO:0045838(positive regulation of membrane potential);GO:0048839(inner ear development);GO:0050750(low-density lipoprotein particle receptor binding);GO:0070062(extracellular exosome)	04960(Aldosterone-regulated sodium reabsorption)	NA	NA	"solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076]"	9.89	7	9.55	2.77	3.78	4.62	2.56	1.36	0	0.15	up	yes
MSTRG.9910	CCNF	ENST00000293968;ENST00000397066;ENST00000569093;ENST00000564333;ENST00000564236	GO:0000320(re-entry into mitotic cell cycle);GO:0001890(placenta development);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005814(centriole);GO:0007067(mitotic nuclear division);GO:0010826(negative regulation of centrosome duplication);GO:0016567(protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0051301(cell division);GO:0051726(regulation of cell cycle)	NA	NA	NA	cyclin F [Source:HGNC Symbol;Acc:HGNC:1591]	0.52	0.42	0.44	6.65	18.47	3.96	0.16	-2.68	0.05	0.34	down	yes
MSTRG.9913	C16orf59	ENST00000361837;ENST00000569496;ENST00000567489;ENST00000565537;ENST00000569665;ENST00000569994;ENST00000563531;ENST00000569664;ENST00000483320;ENST00000562253;ENST00000568753;ENST00000565716;ENST00000566580	GO:0005515(protein binding)	NA	NA	NA	chromosome 16 open reading frame 59 [Source:HGNC Symbol;Acc:HGNC:25849]	1.17	1.33	1.15	4.97	4.91	3.91	0.37	-1.43	0	0.13	down	yes
MSTRG.9942	FLYWCH1	MSTRG.9942.1;MSTRG.9942.2;ENST00000253928;ENST00000571140;ENST00000416288;ENST00000570425;ENST00000573525;ENST00000570759;ENST00000573564;ENST00000344592;ENST00000570752;ENST00000574985;ENST00000571983	GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0046872(metal ion binding)	NA	NA	NA	FLYWCH-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:25404]	8.82	9.32	11.2	2.48	2.76	2.56	2.94	1.56	0	0.15	up	yes
MSTRG.9946	PKMYT1	ENST00000571102;MSTRG.9946.2;ENST00000574333;ENST00000440027;ENST00000262300;ENST00000575040;ENST00000575981;ENST00000574680;ENST00000574385;ENST00000574730;ENST00000573944;ENST00000382240;ENST00000576268;ENST00000574415;ENST00000575632;ENST00000572059;ENST00000572619;ENST00000570649;ENST00000572658	"GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000139(Golgi membrane);GO:0000278(mitotic cell cycle);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0007049(cell cycle);GO:0007067(mitotic nuclear division);GO:0007088(regulation of mitotic nuclear division);GO:0010923(negative regulation of phosphatase activity);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0046872(metal ion binding);GO:0051726(regulation of cell cycle)"	04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)	NA	NA	"protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:HGNC:29650]"	0.52	0.41	0.23	4.01	4.48	1.59	0.29	-1.78	0.04	0.3	down	yes
MSTRG.9960	ZNF205	ENST00000382192;ENST00000219091;ENST00000620094;ENST00000444510;ENST00000414351;ENST00000570935	"GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003700(sequence-specific DNA binding transcription factor activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0010729(positive regulation of hydrogen peroxide biosynthetic process);GO:0046872(metal ion binding);GO:1901030(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)"	NA	NA	NA	zinc finger protein 205 [Source:HGNC Symbol;Acc:HGNC:12996]	9	7.78	8.9	2.98	3.39	3.43	2.41	1.27	0	0.08	up	yes
MSTRG.9973	SLX4	ENST00000294008;ENST00000466154;ENST00000486524	"GO:0000724(double-strand break repair via homologous recombination);GO:0000784(nuclear chromosome, telomeric region);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0006289(nucleotide-excision repair);GO:0008047(enzyme activator activity);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:0017108(5'-flap endonuclease activity);GO:0030054(cell junction);GO:0033557(Slx1-Slx4 complex);GO:0043085(positive regulation of catalytic activity);GO:0048257(3'-flap endonuclease activity);GO:0048476(Holliday junction resolvase complex);GO:0070522(ERCC4-ERCC1 complex);GO:0072429(response to intra-S DNA damage checkpoint signaling)"	NA	NA	NA	SLX4 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:23845]	0.28	0.41	0.72	2.94	2.55	1.73	0.38	-1.4	0.01	0.21	down	yes
MSTRG.998	ORC1	ENST00000371568;ENST00000371566	GO:0000082(G1/S transition of mitotic cell cycle);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000808(origin recognition complex);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005664(nuclear origin of replication recognition complex);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006260(DNA replication);GO:0006270(DNA replication initiation);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0070318(positive regulation of G0 to G1 transition)	04110(Cell cycle)	NA	NA	"origin recognition complex, subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487]"	2.05	2.48	1.32	16.08	15.32	6.83	0.18	-2.47	0.02	0.25	down	yes