The PDF file includes:
- Fig. S1. Myosin motors cluster over time.
- Fig. S2. Temporal behavior of root mean square velocity.
- Fig. S3. Myosin motors do not localize to defect cores.
- Fig. S4. Time averaging of defect spacing.
- Fig. S5. Effect of flow alignment on the change of defect morphology.
- Fig. S6. Director field associated with different defect orientations.
- Supplementary Text
- Legends for movies S1 to S10
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Other Supplementary Material for this manuscript includes the following:
- Movie S1 (.avi format). Crowding of actin filaments (mean length, l = 1 μm) on an oil-water interface forming a 2D nematic LC.
- Movie S2 (.avi format). A dense film of actin filaments (red, l = 1 μm) and myosin II (green) form an active nematic.
- Movie S3 (.avi format). Generation of topological defect pairs in actomyosin-based active nematic (l = 1 μm).
- Movie S4 (.avi format). Persistent motion of a +1/2 defect (solid symbol) along its orientation in our actomyosin-based active nematics (l = 1 μm); −1/2 (open symbol) defect remains immobile.
- Movie S5 (.avi format). Fluorescence images of actin (left) and myosin (right) in actin nematic (l = 2 μm).
- Movie S6 (.avi format). Time-lapse imaging of fluorescent actin in a passive nematic LC (l = 1 μm, c = 0 μm−2) showing annihilation of defect pairs.
- Movie S7 (.avi format). Time-lapse imaging of fluorescent actin in an active nematic LC (l = 1 μm, c = 0.01 μm−2) showing defect repulsion.
- Movie S8 (.avi format). Time-lapse imaging of fluorescent actin in an active nematic LC (l = 1 μm, c = 0.0015 μm−2) showing defect stalling, where the defect pair separation (indicated by open symbols) does not change significantly over the course of 3 min.
- Movie S9 (.avi format). Simulation movie of defect dynamics in a quasi-2D active nematic LC.
- Movie S10 (.avi format). Time-lapse imaging of ± defect pair dynamics in active nematic LC (l = 1 μm, c = 0.0015 μm−2) showing that defect orientations change from roughly antiparallel at large separation to parallel when close, consistent with the structural analysis of defects in simulations.