Gene,Number of SNV,SKAT-O p-value,Rank LOC100129175,10,0.00016662,1 CCDC108,18,0.000336202,2 AMOTL2,8,0.005771787,3 C14orf79,3,0.006322994,4 DDR1,4,0.010454261,5 ADM2,3,0.017330216,6 TMEM62,3,0.017643612,7 PPP3CC,2,0.020251429,8 AKR1C3,4,0.028923866,9 KLHDC4,8,0.035360878,10 DPYD,9,0.035409337,11 DSEL,5,0.036728665,12 CAMTA1,8,0.037234756,13 SOD3,4,0.038375649,14 NOMO1,7,0.04397014,15 EML6,12,0.044720249,16 FAM221A,5,0.046053529,17 PDGFRA,7,0.046282786,18 MACC1,8,0.048858055,19 IQCC,4,0.059615679,20 TCF7L2,3,0.059769546,21 GLS2,1,0.061053609,22 ZNF479,5,0.070471655,23 LCMT2,7,0.071585117,24 IFT172,10,0.097701787,25 WFDC10B,1,0.104678143,26 PSME3,1,0.107536728,27 COMMD2,1,0.107833738,28 POC5,7,0.10886549,29 YLPM1,11,0.109717278,30 ANKS6,7,0.109816205,31 DST,52,0.114460366,32 SIDT1,12,0.117219834,33 TATDN2,7,0.117619809,34 ELMOD1,2,0.118715946,35 STX2,2,0.118918189,36 ANKZF1,5,0.119491123,37 KIF19,14,0.119592334,38 OR13J1,1,0.120829485,39 SPSB4,3,0.124398689,40 EFCAB4B,10,0.128885674,41 ZNF317,2,0.131121293,42 BRD8,7,0.132813139,43 TXNRD1,3,0.13849023,44 ACKR4,2,0.142195582,45 AGAP2,9,0.143631646,46 TUBD1,3,0.145920473,47 SPNS3,11,0.147496519,48 BEND5,2,0.155951249,49 C3orf67,2,0.165987099,50 GPRC6A,9,0.169233029,51 PPEF2,8,0.173086449,52 ZC3HAV1,8,0.17818932,53 TTC16,8,0.178639642,54 QARS,2,0.193434408,55 EYS,32,0.200822513,56 FGG,3,0.200862182,57 PTPN14,5,0.202156401,58 SPRY4,3,0.219063461,59 RAD54L,4,0.221663993,60 OR13C3,1,0.222820372,61 TMEM39B,2,0.225899762,62 GLI3,12,0.229039561,63 GPC2,2,0.230041223,64 CABYR,4,0.235356903,65 CD177,10,0.237264186,66 CRISPLD2,7,0.241313942,67 CTSF,4,0.2452863,68 NEK3,6,0.24706582,69 CCDC92,1,0.254591827,70 C22orf24,2,0.259741574,71 FAM207A,3,0.260304092,72 SSTR3,5,0.264019003,73 SUZ12,1,0.27149226,74 SCAMP2,4,0.278706725,75 PTTG2,2,0.284032536,76 MST1,8,0.285162054,77 NRDE2,11,0.286886674,78 BAAT,5,0.291971513,79 DEFB1,1,0.296149593,80 GP5,3,0.298413032,81 TGFB1,4,0.299813801,82 PGR,9,0.305503573,83 ROCK1,3,0.309255698,84 TMEM63B,1,0.314671885,85 ITFG3,12,0.317432121,86 SEPT8,5,0.319410868,87 TUB,3,0.322477511,88 FNDC7,10,0.322535388,89 SCNN1A,11,0.324520206,90 PDZD9,1,0.325468402,91 RASGEF1B,3,0.331191227,92 EHHADH,9,0.336921705,93 HIVEP1,21,0.337631814,94 WDR3,4,0.339478872,95 FRMD5,5,0.342848567,96 WDR92,2,0.345953722,97 CCNJL,5,0.348231261,98 C7orf57,7,0.350631231,99 CLEC3A,2,0.35093702,100 TP53BP2,7,0.353495786,101 LRMP,1,0.369414438,102 PAX3,1,0.37252275,103 CENPM,3,0.374070631,104 ST5,7,0.374949654,105 APOA4,7,0.377813217,106 TTC40,39,0.377924899,107 BBOX1,3,0.378486028,108 ICK,1,0.381077212,109 TRPM2,16,0.383628297,110 OR1F1,4,0.386154268,111 MGME1,3,0.389000204,112 TET1,12,0.3916377,113 PTPRF,7,0.393567606,114 TRIM17,1,0.39602528,115 TCF7,4,0.400954256,116 OR5AK2,4,0.410874671,117 RBMXL1,3,0.410897317,118 FAT1,40,0.414934989,119 BAG3,5,0.420737511,120 COL14A1,10,0.422738853,121 SLIT1,5,0.434218261,122 TAGAP,4,0.437804251,123 C17orf67,2,0.451163025,124 ELSPBP1,7,0.452923331,125 UPB1,2,0.459916148,126 OSR1,1,0.460557745,127 LOC101054525,1,0.474985335,128 CDHR3,10,0.477137111,129 C15orf56,4,0.481417818,130 NAA15,1,0.482318741,131 OSER1,1,0.483985606,132 CLDN14,2,0.485113259,133 NR2C2,2,0.486226749,134 SIRT4,3,0.486810259,135 ALS2CL,8,0.493729593,136 ZC3H12D,7,0.498369032,137 IGSF3,12,0.500848699,138 IGSF10,24,0.502798968,139 IL20RA,5,0.504185952,140 SBF1,11,0.506015645,141 FGA,3,0.513191628,142 ABCB6,11,0.514136052,143 HTN1,1,0.518246662,144 TBX1,5,0.520899274,145 SH3TC2,11,0.52825833,146 AHSG,5,0.528409647,147 TEX36,4,0.531339838,148 SPINK5,15,0.533379214,149 ZNF224,8,0.539621946,150 VANGL2,7,0.544408324,151 SMCHD1,3,0.544991239,152 C15orf60,2,0.546545635,153 KRIT1,3,0.553743065,154 TCF20,7,0.556995414,155 E2F2,6,0.557674758,156 TMEM63C,3,0.563158109,157 ZNF639,1,0.563245788,158 RUNX1,2,0.563653389,159 SLC2A6,6,0.569290522,160 SERPINE1,3,0.570073606,161 IGSF11,3,0.572956867,162 SPRR2F,2,0.575790475,163 TNKS1BP1,19,0.578123759,164 ZNF48,3,0.578868341,165 CCDC28B,2,0.581605248,166 RSPH3,6,0.583131768,167 ITGB8,2,0.583405353,168 PPP5D1,6,0.599058261,169 C2orf80,1,0.603702698,170 KIF14,11,0.604718648,171 KCNH8,5,0.604755766,172 ZNF229,10,0.608750445,173 PITPNM3,6,0.610073046,174 EPN3,12,0.612260719,175 TYRO3,4,0.615294379,176 PGPEP1L,6,0.615908407,177 FBXO10,4,0.619500945,178 CSDE1,3,0.619757302,179 MYRFL,5,0.62032244,180 ZNF460,3,0.620827835,181 SYNGR3,1,0.621013765,182 POP4,2,0.624114718,183 SEL1L2,3,0.626492238,184 DPY19L4,1,0.627837809,185 FAM92A1,1,0.633544505,186 DOK3,10,0.634980344,187 JPH2,3,0.63551832,188 TRABD2A,5,0.64186418,189 PIGQ,10,0.647994437,190 KIAA0513,5,0.648445302,191 EXPH5,22,0.648687681,192 CDK3,3,0.651273887,193 PPP1R26,15,0.654230949,194 PDLIM5,9,0.66123165,195 GABRA1,1,0.666383131,196 NKX2-6,4,0.666395591,197 PROSC,4,0.667561813,198 SRSF4,4,0.667803162,199 ABCB11,6,0.66931631,200 GRAMD3,2,0.671136224,201 FAM111B,1,0.675845571,202 SEMA5A,5,0.683319028,203 SEC63,1,0.69365354,204 C5AR1,2,0.694708033,205 CEACAM20,9,0.699043784,206 FAM151B,2,0.700370359,207 CHRNB4,8,0.703270605,208 SLC3A2,1,0.713943167,209 POU5F1B,2,0.713945385,210 MIOS,1,0.714028791,211 NGEF,4,0.7154664,212 OR10Z1,4,0.719315215,213 SLC1A7,8,0.719443175,214 PGGT1B,1,0.724336122,215 PPP2R3A,16,0.72961438,216 PCSK4,14,0.737815261,217 TM7SF3,3,0.739725275,218 DGKI,3,0.740415824,219 FBXO47,2,0.741532246,220 C22orf42,5,0.742642126,221 ELAC2,4,0.749019232,222 DCAF5,5,0.751074258,223 CGN,10,0.753529422,224 USP18,3,0.765042374,225 TCP11L1,6,0.766491107,226 BSDC1,3,0.779188312,227 ZNF766,6,0.779664996,228 SMYD4,13,0.781470493,229 SMARCA5,1,0.782064174,230 AGBL2,4,0.786905647,231 DES,3,0.789145945,232 PAFAH2,2,0.79636447,233 TRMT12,4,0.803499629,234 CCDC88B,19,0.804870281,235 CES3,5,0.80728923,236 SIPA1L3,14,0.81102155,237 OR6V1,6,0.813242233,238 PHLPP1,13,0.813326748,239 SDR39U1,6,0.814313388,240 SGOL2,5,0.815083007,241 CHRNA2,5,0.816924856,242 SLC25A12,2,0.825486609,243 TMEM81,3,0.83015909,244 ARV1,1,0.832644408,245 MICALL2,16,0.833476151,246 CALR3,1,0.833837268,247 COX6C,1,0.83436696,248 UGCG,1,0.835093737,249 PMVK,3,0.837823708,250 KYNU,3,0.838930384,251 OPRM1,8,0.844003967,252 ZC3H10,2,0.846138381,253 PNMAL2,5,0.848255984,254 RBM38,2,0.84995659,255 CNTN2,11,0.85208934,256 PYROXD2,4,0.856632866,257 EXOC3,2,0.856751182,258 HDAC10,11,0.862500064,259 NAP1L4,1,0.863369442,260 AXDND1,3,0.867755489,261 AKR1E2,4,0.867823784,262 CD1A,4,0.869521766,263 HMCN2,46,0.870549873,264 TRAT1,2,0.873977492,265 TICRR,13,0.878576373,266 SERPINA5,7,0.879042883,267 FAM153B,4,0.88224507,268 PSMG3,2,0.882281876,269 ARHGAP9,11,0.885255581,270 CDC25B,2,0.886926108,271 FGB,4,0.888983967,272 SERTAD1,3,0.893857155,273 ATP13A5,14,0.896221147,274 MYO1F,4,0.896661286,275 BROX,1,0.901374474,276 ATP4B,6,0.907400695,277 XIRP1,13,0.917003218,278 ZNF646,18,0.917924852,279 PLEC,67,0.922945307,280 ABCA4,26,1,281 CA6,4,1,281 DUSP6,3,1,281 FN1,14,1,281 GTF2H4,3,1,281 OVCH2,11,1,281 PPP1R15B,3,1,281 SLC9C1,9,1,281 TMEM260,3,1,281