This PDF file includes:

• Fig. S1. Effects of CPT1 on KCNQ1 channels.
• Fig. S2. Effects of MTX on KCNQ1 channels.
• Fig. S3. Effects of MTX on KCNQ1/KCNE1 channels.
• Fig. S4. Effects of MTX on KCNQ1/SMIT1 channels.
• Fig. S5. Interaction of MTX with permeant ions and UCL2077.
• Fig. S6. MTX and CPT1 bind to R243 on the KCNQ1 S4-S5 linker.
• Fig. S7. Effects of MTX on KCNQ2/KCNQ3 channels.
• Fig. S8. Effects of MTX on KCNQ2-R213A/KCNQ3 channels.
• Fig. S9. Effects of MTX on KCNQ2/KCNQ3-R242A channels.
• Fig. S10. Effects of MTX on KCNQ2-R213A/KCNQ3-R242A channels.

Download PDF