Patient Genotype,True Class,Exon,Wild-Type Amino Acid,Position,Variant Amino Acid,Number of Mutations in Somatic Cancer,Developmental Delay,Leukodystrophy,Macrocephaly,Lhermite-Duclos Disease,Epilepsy,Dysmorphic Features,Breast Fibrocystic Disease,Thyroid Nodule,Hashimoto Disease,Benign Thyroid Growth,Skin Cancer,Colon Cancer,Colon Lipoma,Colon Polyps,Kidney Cancer,Ovarian Cancer,Ovarian Cyst,Mucocutaneous Lesions,Glycogenic Acanthosis,Lipoma,Generalized Overgrowth,mSCM Stability Predictions,SDM Stability Predictions,Imutant Stability Predications,PoPMuSIC Stability Predications,PolyPhen2 Probability,PolyPhen2 False-Positive Rate,PolyPhen2 True Positive Rate,PolyPhen2 d-Score,Provean Score,SIFT Score,SIFT Conservation Score,Accessible Surface Area,Helix Presence,3-10 Helix Presence,Strand Presence,Turn Presence,Bridge Presence,Coil Presence,Phi Angle,Psi Angle
1,ASD,1,M,1,I,1,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.31,-0.43,-1.29,-1.29,0.851,0.0673,0.833,1.136,-2.428,0.1,3.52,105.6,0,0,0,0,0,0,-81.4,125.1
1,ASD,1,M,1,I,1,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.31,-0.43,-1.29,-1.29,0.851,0.0673,0.833,1.136,-2.428,0.1,3.52,105.6,0,0,0,0,0,0,-81.4,125.1
1,PHTS,1,M,1,I,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.31,-0.43,-1.29,-1.29,0.851,0.0673,0.833,1.136,-2.428,0.1,3.52,105.6,0,0,0,0,0,0,-81.4,125.1
1,PHTS,1,M,1,I,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-1.31,-0.43,-1.29,-1.29,0.851,0.0673,0.833,1.136,-2.428,0.1,3.52,105.6,0,0,0,0,0,0,-81.4,125.1
12,PHTS,1,N,12,I,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,1,0,-1.31,-0.43,-1.29,-1.29,0.232,0.121,0.912,2.199,-4.663,0.01,3.38,8.85,0,0,0,0,0,0,-67.93,-19.42
12,ASD,1,N,12,T,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.31,-0.43,-1.29,-1.29,0.041,0.172,0.943,1.451,-2.619,0.2,3.38,8.85,0,0,0,0,0,0,-67.93,-19.42
14,PHTS,1,R,14,G,4,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-0.021,-2.81,-0.46,0.14,0.247,0.119,0.911,1.796,-4.855,0.2,3.38,240.5,0,0,0,0,0,0,360,-19.42
14,PHTS,1,R,14,G,4,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-0.021,-2.81,-0.46,0.14,0.247,0.119,0.911,1.796,-4.855,0.2,3.38,240.5,0,0,0,0,0,0,360,-19.42
16,PHTS,1,Y,16,H,0,0,0,1,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,-0.509,-1.2,-1.14,-0.55,0.003,0.556,0.981,0.751,-3.513,0.02,3.37,108,0,0,0,0,0,0,171.13,-21.68
17,ASD,1,Q,17,E,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.401,-0.43,-0.7,-0.5,0.02,0.198,0.952,1.183,-1.043,0.56,3.37,76.8,0,0,0,0,0,0,-175.89,137.04
23,ASD,1,L,23,F,3,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,-1.752,0.54,-1.48,-0.63,0.999,0.00574,0.136,2.277,-3.543,0,3,10.3,0,0,1,0,0,0,-117.27,148.8
23,PHTS,1,L,23,V,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-1.639,-0.04,-1.65,-0.93,0.997,0.0167,0.409,1.514,-2.442,0,3,10.3,0,0,1,0,0,0,-117.27,148.8
23,ASD,1,L,23,V,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-1.639,-0.04,-1.65,-0.93,0.997,0.0167,0.409,1.514,-2.442,0,3,10.3,0,0,1,0,0,0,-117.27,148.8
23,ASD,1,L,23,V,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-1.639,-0.04,-1.65,-0.93,0.997,0.0167,0.409,1.514,-2.442,0,3,10.3,0,0,1,0,0,0,-117.27,148.8
24,PHTS,1,D,24,G,6,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0.106,-1.28,-1.83,-1.57,0.539,0.095,0.88,1.677,-6.015,0,3,35.7,0,0,1,0,0,0,-80.33,79.37
24,PHTS,1,D,24,H,3,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,1,0,0,0,-0.817,1.45,-0.79,-0.32,0.969,0.045,0.77,2.918,-5.921,0,3,35.7,0,0,1,0,0,0,-80.33,79.37
24,PHTS,1,D,24,N,4,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0.005,-0.33,-1.11,-0.42,0.017,0.205,0.954,0.777,-4.081,0,3,35.7,0,0,1,0,0,0,-80.33,79.37
25,ASD,1,L,25,F,2,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,-1.704,-0.47,-1.45,-0.12,0.943,0.0548,0.797,2.285,-3.41,0.12,3,1.1,0,0,1,0,0,0,-152.87,155.4
26,PHTS,1,T,26,P,2,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-0.774,-1.57,-1.57,-1.85,0.437,0.101,0.891,2.042,-4.346,0.01,3,2.5,0,0,1,0,0,0,-146.27,125.21
27,PHTS,1,Y,27,N,3,0,0,1,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,0,0,0,-2.093,-3.06,-2.08,-1.83,0.597,0.0919,0.874,2.123,-7.241,0,3,34,0,0,1,0,0,0,-73.7,116.7
35,PHTS,2,M,35,V,4,0,0,1,0,0,0,0,1,0,1,0,0,0,1,0,0,0,1,0,0,0,-0.922,-0.79,-1.31,-1.1,0.969,0.045,0.77,1.09,-3.884,0.56,3,0.2,0,0,1,0,0,0,-137.07,177.99
35,ASD,2,M,35,V,5,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-0.922,-0.79,-1.31,-1.1,0.969,0.045,0.77,1.09,-3.884,0.56,3,0.2,0,0,1,0,0,0,-137.07,177.99
35,ASD,2,M,35,V,5,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.922,-0.79,-1.31,-1.1,0.969,0.045,0.77,1.09,-3.884,0.56,3,0.2,0,0,1,0,0,0,-137.07,177.99
36,PHTS,2,G,36,R,7,0,0,1,0,0,0,0,1,0,1,0,0,0,1,0,0,0,1,0,1,0,-1.142,-1.26,-0.94,-0.12,1,0.00026,0.00018,2.849,-7.779,0.05,3,0.4,0,0,0,0,0,0,-95.25,-178.7
38,PHTS,2,P,38,S,2,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,-2.908,-0.58,-2.05,-1.35,1,0.00026,0.00018,2.128,-7.768,0,3,0,0,0,0,0,0,0,-74.57,85.97
39,ASD,2,A,39,T,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.31,-3.14,-0.84,-0.29,1,0.00026,0.00018,1.885,-3.353,0.04,3,0.8,0,0,1,0,0,0,-75.18,133.65
43,ASD,2,E,43,K,1,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.336,-0.19,-0.58,0.03,0.997,0.0167,0.409,1.626,-3.789,0.02,3,125.7,0,0,0,0,0,0,174.12,152.98
43,PHTS,2,E,43,K,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.336,-0.19,-0.58,0.03,0.997,0.0167,0.409,1.626,-3.789,0.02,3,125.7,0,0,0,0,0,0,174.12,152.98
48,PHTS,2,N,48,K,0,0,0,1,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,-0.363,-2.06,-1.53,-1.19,1,0.00026,0.00018,1.847,-5.663,0.05,3,6.5,0,0,0,0,0,0,-69.84,126.42
53,PHTS,2,V,53,I,0,0,0,1,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,-0.527,-0.1,-0.96,-0.67,0.997,0.0167,0.409,1.236,-0.906,0.2,3,0,1,0,0,0,0,0,-62.86,-40.29
61,PHTS,3,H,61,R,3,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,1,0,1,0,-1.151,-0.66,-0.81,-1.49,1,0.00026,0.00018,1.949,-7.344,0,3,24.8,0,0,1,0,0,0,-146.01,88.17
61,ASD,3,H,61,Y,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.469,0.37,-0.56,-0.45,0.999,0.00574,0.136,1.728,-5.208,0,3,24.8,0,0,1,0,0,0,-146.01,88.17
61,PHTS,3,H,61,Y,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.469,0.37,-0.56,-0.45,0.999,0.00574,0.136,1.728,-5.208,0,3,24.8,0,0,1,0,0,0,-146.01,88.17
65,ASD,3,Y,65,C,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-2.108,1.48,-1.65,-2.4,1,0.00026,0.00018,3.458,-8.706,0,3,3.2,0,0,1,0,0,0,-130.65,144.43
68,PHTS,3,Y,68,C,4,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,-1.432,1.65,-1.72,-2.86,1,0.00026,0.00018,3.458,-8.695,0,3,0,0,0,1,0,0,0,-124.3,113.54
68,ASD,3,Y,68,H,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-2.278,-2.29,-1.93,-2.76,1,0.00026,0.00018,2.376,-4.812,0,3,0,0,0,1,0,0,0,-124.3,113.54
68,PHTS,3,Y,68,N,2,0,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,-3.123,-4.75,-2.13,-4.37,1,0.00026,0.00018,2.494,-8.684,0,3,0,0,0,1,0,0,0,-124.3,113.54
68,ASD,3,Y,68,C,4,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.432,1.65,-1.72,-2.86,1,0.00026,0.00018,3.458,-8.695,0,3,0,0,0,1,0,0,0,-124.3,113.54
70,ASD,3,L,70,V,0,1,0,1,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,1,0,-1.688,-0.39,-1.27,-1.23,0.999,0.00574,0.136,1.514,-2.899,0,3,0,0,0,1,0,0,0,-96.25,3.68
70,PHTS,3,L,70,P,1,0,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,-1.688,-4.04,-1.69,-2.35,1,0.00026,0.00018,2.765,-6.768,0,3,0,0,0,1,0,0,0,-96.25,3.68
79,PHTS,4,A,79,T,2,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,1,0,1,0,-0.622,0.45,-0.76,-0.22,0.002,0.704,0.987,0.355,0.085,1,3,82.1,1,1,0,0,0,0,-68.9,-56.03
79,PHTS,4,A,79,T,2,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,-0.622,0.45,-0.76,-0.22,0.002,0.704,0.987,0.355,0.085,1,3,82.1,1,1,0,0,0,0,-68.9,-56.03
79,PHTS,4,A,79,T,2,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,1,0,0,0,-0.622,0.45,-0.76,-0.22,0.002,0.704,0.987,0.355,0.085,1,3,82.1,1,1,0,0,0,0,-68.9,-56.03
88,ASD,5,Y,88,C,9,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-1.631,2.11,-1.31,-2.34,1,0.00026,0.00018,3.376,-8.197,0.28,3,36.3,0,0,1,0,0,0,-135.46,65.8
92,PHTS,5,D,92,A,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,1,0,-0.422,1.45,-0.57,-0.02,1,0.00026,0.00018,2.023,-7.767,0.26,3,59.6,0,0,0,0,0,0,-49.69,119.74
93,PHTS,5,H,93,Y,1,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1.564,0.35,0.09,-0.28,0.999,0.00574,0.136,1.728,-5.65,0.15,3,113,0,0,0,0,0,0,70.78,11.66
93,ASD,5,H,93,Y,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,1.564,0.35,0.09,-0.28,0.999,0.00574,0.136,1.728,-5.65,0.15,3,113,0,0,0,0,0,0,70.78,11.66
95,PHTS,5,P,95,L,5,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0.005,0.92,-0.88,-0.27,1,0.00026,0.00018,2.325,-7.783,0.21,3,8.5,0,0,0,0,0,0,-83.93,165.01
95,ASD,5,P,95,T,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-1.658,-2.23,-1.79,-1.29,1,0.00026,0.00018,2.163,-5.967,0.36,3,8.5,0,0,0,0,0,0,-83.93,165.01
96,PHTS,5,P,96,R,0,0,1,1,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,1,0,-1.823,-1.53,-1.5,-1.69,1,0.00026,0.00018,2.675,-8.475,0,3,2.4,0,0,0,0,0,0,-86.29,172.25
100,PHTS,5,L,100,P,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,1,0,0,-1.188,-1.23,-1.59,-2.74,1,0.00026,0.00018,2.765,-5.936,0.27,3,41.59,1,0,0,0,0,0,-67.93,-19.42
101,ASD,5,I,101,T,8,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,-2.97,-4.03,-2.45,-2.13,1,0.00026,0.00018,1.885,-4.775,0.01,3,0,1,0,0,0,0,0,-60.26,-61.17
108,PHTS,5,L,108,P,3,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,-1.287,-4.85,-2.29,-4.16,0.997,0.0167,0.409,2.427,-4.414,0.02,3,0,1,0,0,0,0,0,-56.63,-45.78
108,PHTS,5,L,108,R,0,0,0,1,1,0,0,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,-2.124,-3.25,-1.97,-1.58,0.997,0.0167,0.409,2.411,-4.578,0.01,3,0,1,0,0,0,0,0,-56.63,-45.78
108,PHTS,5,L,108,P,3,0,0,1,1,0,0,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,-1.287,-0.39,-2.29,-4.16,0.997,0.0167,0.409,2.427,-4.414,0.02,3,0,1,0,0,0,0,0,-56.63,-45.78
111,ASD,5,W,111,R,2,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,-2.362,-3.5,-1.48,-2.63,0.928,0.058,0.806,2.534,-12.459,0,3,19.4,1,0,0,0,0,0,-61.24,-40.22
120,PHTS,5,A,120,E,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,-2.443,-3.71,-1.06,-2.76,1,0.00026,0.00018,2.129,-4.442,0.04,3,0,0,0,1,0,0,0,-133,131.76
122,ASD,5,I,122,S,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-3.476,-4.99,-2.22,-4.22,0.998,0.0112,0.273,2.055,-5.517,0,3,0,0,0,1,0,0,0,-97.97,136.41
124,ASD,5,C,124,R,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,-1.111,-2.58,-0.84,-2.05,1,0.00026,0.00018,2.642,-11.708,0.01,3,4,0,0,0,0,0,0,-129.29,-126.31
126,PHTS,5,A,126,P,2,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,-0.452,-0.43,-0.36,-1.29,1,0.00026,0.00018,2.344,-4.778,0.03,3,44.9,0,0,1,0,0,0,-108.65,8.66
127,ASD,5,G,127,E,5,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,-2.395,-3.36,-1.45,-3.25,1,0.00026,0.00018,2.581,-7.306,0.02,3,0.8,0,0,1,0,0,0,62.14,51.3
128,PHTS,5,K,128,E,0,1,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,0.245,-0.43,-1.15,-0.4,0.999,0.00574,0.136,1.601,-3.903,0.02,3,82.8,0,0,1,0,0,0,-121.1,-102.44
128,PHTS,5,K,128,N,6,0,0,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,1,0,0,0,-0.035,-0.15,-1.05,-0.5,1,0.00026,0.00018,2.059,-4.878,0.01,3,82.8,0,0,1,0,0,0,-121.1,-102.44
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