{"text_format":"2","workbook":"xlsx","n_sheets":9,"sheets":["Overview","TP Mutations","TP Polymorphisms","FN Mutations","FN Polymorphisms","FP Mutations","FP Polymorphisms","TN Mutations Filter 2","TN Mutations Filter 1"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Overview","index":0,"n_rows":62,"n_cols":13,"rows_kept":62,"cut":false,"hidden":false,"merged":[[0,1,0,7],[13,1,13,7],[18,1,18,7],[23,1,23,7],[35,1,35,7],[48,1,48,7],[53,1,53,7],[58,1,58,7]]}
["training set 2; n=111","1 tool, no filter (20, 50, 0.01)"]
[null,"Mutations (TP)","Polymorphisms (TP)","Mutations (FN)","Polymorphisms (FN)","No Mutations (FP_M)","No Mutations (FP_P)","No Mutations (TN2)","No Mutations (TN1)","Variants","Artifacts","sens","PPV"]
["GATK",154,362,0,0,12,0,141,57,{"$f":"SUM(B3:E3)","v":516},{"$f":"SUM(F3:I3)","v":210},{"$f":"J3/631","v":0.817749603803486},{"$f":"J3/(J3+K3)","v":0.710743801652893}]
["Platypus",182,401,2,0,18,0,684,92,{"$f":"SUM(B4:E4)","v":585},{"$f":"SUM(F4:I4)","v":794},{"$f":"J4/631","v":0.927099841521395},{"$f":"J4/(J4+K4)","v":0.42422044960116}]
["VarScan",77,217,0,0,5,0,98,5,{"$f":"SUM(B5:E5)","v":294},{"$f":"SUM(F5:I5)","v":108},{"$f":"J5/631","v":0.465927099841521},{"$f":"J5/(J5+K5)","v":0.73134328358209}]
["LoFreq",174,314,2,0,23,1,1624,0,{"$f":"SUM(B6:E6)","v":490},{"$f":"SUM(F6:I6)","v":1648},{"$f":"J6/631","v":0.776545166402536},{"$f":"J6/(J6+K6)","v":0.229186155285313}]
["FreeBayes",215,401,11,0,37,1,8075,32046,{"$f":"SUM(B7:E7)","v":627},{"$f":"SUM(F7:I7)","v":40159},{"$f":"J7/631","v":0.993660855784469},{"$f":"J7/(J7+K7)","v":0.0153729220811063}]
["SNVer",124,214,6,0,20,0,3373,983,{"$f":"SUM(B8:E8)","v":344},{"$f":"SUM(F8:I8)","v":4376},{"$f":"J8/631","v":0.545166402535658},{"$f":"J8/(J8+K8)","v":0.0728813559322034}]
["SAMtools",67,335,0,0,5,0,102,12,{"$f":"SUM(B9:E9)","v":402},{"$f":"SUM(F9:I9)","v":119},{"$f":"J9/631","v":0.637083993660856},{"$f":"J9/(J9+K9)","v":0.771593090211132}]
["VarDict",196,390,9,0,36,0,3436,36,{"$f":"SUM(B10:E10)","v":595},{"$f":"SUM(F10:I10)","v":3508},{"$f":"J10/631","v":0.942947702060222},{"$f":"J10/(J10+K10)","v":0.14501584206678}]
[null,219,401,11,0,39,1,8366,32060,{"$f":"SUM(B11:E11)","v":631},{"$f":"SUM(F11:I11)","v":40466}]
[]
[]
[null,"8 tools, no filter (20, 50, 0.01)"]
[null,"Variants","Artifacts","sens","PPV"]
[null,{"$f":"SUM(B11,C11,D11,E11)","v":631},{"$f":"K11","v":40466},{"$f":"B16/B17","v":1},{"$f":"B16/(B16+C16)","v":0.0153539187775263}]
[null,{"$f":"J11","v":631}]
[]
[null,"8 tools, our filter; single sample info"]
[null,"Mutations","Artifacts","sens","PPV"]
[null,622,1177,{"$f":"Overview!B21/B22","v":0.985736925515055},{"$f":"Overview!B21/(Overview!B21+Overview!C21)","v":0.345747637576431}]
[null,631]
[]
[null,"8 tools our filter"]
[null,"Variants","Artifacts","sens","PPV"]
[null,{"$f":"SUM(B11,C11)","v":620},{"$f":"SUM(F11,G11)","v":40},{"$f":"B26/B27","v":0.98256735340729},{"$f":"B26/(B26+C26)","v":0.939393939393939}]
[null,{"$f":"J11","v":631}]
{"$rows_empty":8}
["Mutations only","1 tool, no filter (20, 50, 0.01)"]
[null,"Mutations (TP)","Mutations (FN)","No Mutations (FP_M)","No Mutations (TN2)","No Mutations (TN1)","Variants","Artifacts","sens","PPV"]
["GATK",154,0,13,141,57,{"$f":"SUM(B38,C38)","v":154},{"$f":"SUM(D38,E38,F38)","v":211},{"$f":"G38/230","v":0.669565217391304},{"$f":"G38/(G38+H38)","v":0.421917808219178}]
["Platypus",182,2,20,684,92,{"$f":"SUM(B39,C39)","v":184},{"$f":"SUM(D39,E39,F39)","v":796},{"$f":"G39/230","v":0.8},{"$f":"G39/(G39+H39)","v":0.187755102040816}]
["VarScan",77,0,5,98,5,{"$f":"SUM(B40,C40)","v":77},{"$f":"SUM(D40,E40,F40)","v":108},{"$f":"G40/230","v":0.334782608695652},{"$f":"G40/(G40+H40)","v":0.416216216216216}]
["LoFreq",174,2,25,1624,0,{"$f":"SUM(B41,C41)","v":176},{"$f":"SUM(D41,E41,F41)","v":1649},{"$f":"G41/230","v":0.765217391304348},{"$f":"G41/(G41+H41)","v":0.0964383561643836}]
["FreeBayes",215,11,39,8075,32046,{"$f":"SUM(B42,C42)","v":226},{"$f":"SUM(D42,E42,F42)","v":40160},{"$f":"G42/230","v":0.982608695652174},{"$f":"G42/(G42+H42)","v":0.00559599861338087}]
["SNVer",124,6,22,3373,983,{"$f":"SUM(B43,C43)","v":130},{"$f":"SUM(D43,E43,F43)","v":4378},{"$f":"G43/230","v":0.565217391304348},{"$f":"G43/(G43+H43)","v":0.0288376220053239}]
["SAMtools",67,0,6,102,12,{"$f":"SUM(B44,C44)","v":67},{"$f":"SUM(D44,E44,F44)","v":120},{"$f":"G44/230","v":0.291304347826087},{"$f":"G44/(G44+H44)","v":0.358288770053476}]
["VarDict",196,9,38,3436,36,{"$f":"SUM(B45,C45)","v":205},{"$f":"SUM(D45,E45,F45)","v":3510},{"$f":"G45/230","v":0.891304347826087},{"$f":"G45/(G45+H45)","v":0.0551816958277254}]
[null,219,11,41,8366,32060,{"$f":"SUM(B46,C46)","v":230},{"$f":"SUM(D46,E46,F46)","v":40467}]
[]
[]
[null,"8 tools, no filter (20, 50, 0.01)"]
[null,"Variants","Artifacts","sens","PPV"]
[null,{"$f":"SUM(B46,C46)","v":230},{"$f":"H46","v":40467},{"$f":"B51/B52","v":1},{"$f":"B51/(B51+C51)","v":0.00565152222522545}]
[null,{"$f":"G46","v":230}]
[]
[null,"8 tools, our filter; single sample info"]
[null,"Mutations","Artifacts","sens","PPV"]
[null,221,1184,{"$f":"Overview!B56/B57","v":0.960869565217391},{"$f":"Overview!B56/(Overview!B56+Overview!C56)","v":0.15729537366548}]
[null,230]
[]
[null,"8 tools our filter"]
[null,"Variants","Artifacts","sens","PPV"]
[null,{"$f":"SUM(B46)","v":219},{"$f":"SUM(D46)","v":41},{"$f":"B61/B62","v":0.952173913043478},{"$f":"B61/(B61+C61)","v":0.842307692307692}]
[null,{"$f":"G46","v":230}]

{"sheet":"TP Mutations","index":1,"n_rows":221,"n_cols":50,"rows_kept":221,"cut":false,"hidden":false,"merged":[]}
["True, because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["Hotspot","UPN_Tr2_049",1,115256530,"G","T","NRAS","ENST00000369535","missense_variant","Caa/Aaa|p.Gln61Lys/c.181C>A",485,24,509,0.0471512770137525,0,0,0,0,1,0,0,1,2,"NO","NO","COSM580","autonomic_ganglia, biliary_tract, bone, breast, central_nervous_system, cervix, endometrium, eye, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, liver, lung, meninges, NS, ovary, pancreas, pleura, prostate, skin, soft_tissue, stomach, thyroid, urinary_tract","5, 2, 4, 2, 5, 2, 2, 2, 91, 1, 100, 3, 18, 3, 1322, 1, 2, 1, 1, 513, 24, 2, 71, 2","NO","rs121913254","YES","NO","NO","NO",-3.817,"Deleterious",31.58,32.38,467,24,491,0.0488798370672098,18,0,18,0,1,1,1,"Hotspot (-3)"]
["Hotspot, 2nd Illumina","UPN_Tr2_001",1,115258744,"C","A","NRAS","ENST00000369535","missense_variant","gGt/gTt|p.Gly13Val/c.38G>T",10205,320,10552,0.0303260045489007,0,0,0,0,1,0,0,1,2,"NO","NO","COSM574","adrenal_gland, central_nervous_system, haematopoietic_and_lymphoid_tissue, large_intestine, skin, soft_tissue","1, 1, 48, 4, 18, 1","NO","rs121434596","YES","NO","NO","NO",-7.664,"Deleterious",35.04,29.65,10205,320,10552,0.0303260045489007,0,0,0,"NA",1,2,3,"Hotspot (-4)"]
["Hotspot, 2nd Illumina, Expert, 454 validated, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_001",1,115258747,"C","T","NRAS","ENST00000369535","missense_variant","gGt/gAt|p.Gly12Asp/c.35G>A",7560,2946,10551,0.279215240261587,1,1,1,1,1,0,1,1,7,0.0116,"NO","COSM564","biliary_tract, central_nervous_system, endometrium, genital_tract, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, lung, NS, ovary, pancreas, skin, soft_tissue, testis, thyroid, upper_aerodigestive_tract","4, 5, 4, 2, 381, 1, 60, 1, 570, 1, 1, 61, 2, 3, 2, 1","NO","rs121913237","YES",1.647E-005,"NO","NO",-5.5,"Deleterious",34.7,34.41,7560,2946,10551,0.279215240261587,0,0,0,"NA",1,2,2,"Hotspot (-9)"]
["Hotspot, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_017",1,115258747,"C","T","NRAS","ENST00000369535","missense_variant","gGt/gAt|p.Gly12Asp/c.35G>A",3429,2899,6341,0.457183409556852,1,1,1,1,1,0,1,1,7,0.0116,"NO","COSM564","biliary_tract, central_nervous_system, endometrium, genital_tract, haematopoietic_and_lymphoid_tissue, kidney, large_intestine, lung, NS, ovary, pancreas, skin, soft_tissue, testis, thyroid, upper_aerodigestive_tract","4, 5, 4, 2, 381, 1, 60, 1, 570, 1, 1, 61, 2, 3, 2, 1","NO","rs121913237","YES",1.647E-005,"NO","NO",-5.5,"Deleterious",34.75,34.56,3429,2899,6341,0.457183409556852,0,0,0,"NA",1,2,2,"Hotspot (-9)"]
["Inspected, 454 validated","UPN_Tr2_008",2,25457180,"C","T","DNMT3A","ENST00000264709","missense_variant","Gct/Act|p.Ala903Thr/c.2707G>A",9094,1233,10335,0.119303338171263,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO",8.236E-006,"NO","NO",-3.235,"Deleterious",35.3,34.82,9094,1233,10335,0.119303338171263,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["Hotspot","UPN_Tr2_087",2,25457242,"C","T","DNMT3A","ENST00000264709","missense_variant","cGc/cAc|p.Arg882His/c.2645G>A",3298,172,3477,0.0494679321253955,0,0,0,0,1,1,0,1,3,0.0581,"NO","COSM52944","breast, haematopoietic_and_lymphoid_tissue","1, 452","NO","rs147001633","NO","NA","NO","NO",-4.025,"Deleterious",31.69,32.68,1665,86,1754,0.0490307867730901,1633,86,1723,0.0499129425420778,0.937714978339398,2,2,"Hotspot (-4)"]
["Hotspot","UPN_Tr2_111",2,25457242,"C","T","DNMT3A","ENST00000264709","missense_variant","cGc/cAc|p.Arg882His/c.2645G>A",8277,97,8388,0.0115641392465427,0,0,0,0,1,1,0,1,3,0.0581,"NO","COSM52944","breast, haematopoietic_and_lymphoid_tissue","1, 452","NO","rs147001633","NO","NA","NO","NO",-4.025,"Deleterious",31.64,33.53,4169,49,4222,0.0116058739933681,4108,48,4166,0.0115218434949592,1,2,2,"Hotspot (-2)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_092",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",1887,1647,3542,0.464991530208922,1,1,0,1,1,1,1,1,7,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.1,34.7,950,829,1781,0.465468837731611,937,818,1761,0.464508801817149,1,6,6,"Hotspot (-7)"]
["Hotspot, Expert, inspected, Cosmic, prediction, bq","UPN_Tr2_081",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",4607,2930,7575,0.386798679867987,1,1,0,1,1,1,1,1,7,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.3,33.27,2328,1477,3824,0.386244769874477,2279,1453,3751,0.387363369768062,0.924702881094088,6,6,"Hotspot (-7)"]
["Hotspot, Expert, inspected, Cosmic, prediction, bq","UPN_Tr2_094",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",6183,2524,8723,0.289349994268027,1,1,0,1,1,1,1,1,7,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.21,34.64,3106,1275,4386,0.290697674418605,3077,1249,4337,0.287987087848743,0.813318404653898,6,6,"Hotspot (-7)"]
["Hotspot, inspected","UPN_Tr2_097",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",9578,226,9828,0.022995522995523,0,0,0,0,1,1,0,1,3,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.04,34.52,4815,115,4942,0.0232699312019425,4763,111,4886,0.0227179697093737,0.892985755462073,6,6,"Hotspot (-2)"]
["Expert, bq, freq","UPN_Tr2_072",2,25458676,"T","C","DNMT3A","ENST00000264709","missense_variant","Att/Gtt|p.Ile833Val/c.2497A>G",25530,9308,34970,0.266171003717472,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO",-0.744,"Tolerated",33.7,32.2,12869,4704,17641,0.266651550365626,12661,4604,17329,0.265681805066651,0.836914317428348,1,1,"Probably True (-4)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_053",2,25463184,"G","A","DNMT3A","ENST00000264709","missense_variant","tCg/tTg|p.Ser770Leu/c.2309C>T",14042,3059,17126,0.178617307018568,1,1,0,1,1,0,0,1,5,"NO","NO","COSM231549","haematopoietic_and_lymphoid_tissue",4,"NO","NO","NO","NO","NO","NO",-4.738,"Deleterious",35.13,35.37,14017,3059,17101,0.178878428162096,25,0,25,0,0.0151177121468114,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_066",2,25463289,"T","C","DNMT3A","ENST00000264709","missense_variant","tAc/tGc|p.Tyr735Cys/c.2204A>G",5273,199,5524,0.0360246198406951,0,0,0,0,1,1,0,1,3,0.0116,"NO","COSM133126","haematopoietic_and_lymphoid_tissue",5,"NO","rs147828672","NO","NA","NO","NO",-6.941,"Deleterious",30.7,32.38,2627,97,2763,0.0351067680057908,2646,102,2761,0.0369431365447302,0.773212031873588,2,2,"Probably True (-1)"]
["Hotspot, Expert, prediction, bq","UPN_Tr2_077",2,25463299,"A","G","DNMT3A","ENST00000264709","missense_variant","Ttt/Ctt|p.Phe732Leu/c.2194T>C",4545,2776,7341,0.37815011578804,1,1,1,1,1,0,1,1,7,"NO","NO","COSM4383544","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-5.838,"Deleterious",33.38,34.64,0,0,0,"NA",4545,2776,7341,0.37815011578804,1,1,1,"Probably True (-6)"]
["Sanger validated, 454 validated, IonT_1 validated, Expert, bq","UPN_Tr2_039",2,25463307,"C","T","DNMT3A","ENST00000264709","missense_variant","cGg/cAg|p.Arg729Gln/c.2186G>A",10669,5202,15906,0.327046397585817,1,1,1,1,1,0,1,1,7,"NO","NO","COSM1318938","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",1.647E-005,"NO","NO",-2.914,"Deleterious",34.76,34.2,0,0,0,"NA",10669,5202,15906,0.327046397585817,1,1,2,"Probably True (-5)"]
["454 validated, Expert","UPN_Tr2_037",2,25463544,"AG","A","DNMT3A","ENST00000264709","frameshift_variant","ctc/|p.Leu713fs/c.2137delC",19048,2376,21454,0.110748578353687,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",35.64,"NA",7604,39,7650,0.00509803921568627,11444,2337,13804,0.169298753984352,2,1,1,"Probably True (-2)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_030",2,25466800,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgg/Tgg|p.Arg635Trp/c.1903C>T",3337,2851,6202,0.459690422444373,1,1,1,1,1,0,1,1,7,0,0,"COSM87012","haematopoietic_and_lymphoid_tissue",8,"NO","rs144689354","NO",3.052E-005,"NO","NO",-7.543,"Deleterious",34.52,34.35,3337,2851,6202,0.459690422444373,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_032",2,25467123,"GT","G","DNMT3A","ENST00000264709","frameshift_variant","tac/|p.Tyr584fs/c.1751delA",2634,244,2900,0.0841379310344828,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.47,"NA",0,0,0,"NA",2634,244,2900,0.0841379310344828,1,1,1,"Probably True (-3)"]
["Expert, prediction, bq","UPN_Tr2_053",2,25467204,"G","C","DNMT3A","ENST00000264709","missense_variant","tgC/tgG|p.Cys557Trp/c.1671C>G",8698,1908,10634,0.179424487492947,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-7.607,"Deleterious",34.9,35.21,0,0,0,"NA",8698,1908,10634,0.179424487492947,1,1,1,"Probably True (-5)"]
["454 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_005",2,25467449,"C","A","DNMT3A","ENST00000264709","missense_variant","Ggc/Tgc|p.Gly543Cys/c.1627G>T",944,651,1603,0.406113537117904,1,1,1,1,1,0,1,1,7,"NO","NO","COSM87002","haematopoietic_and_lymphoid_tissue",13,"NO","NO","NO",3.295E-005,"NO","NO",-7.59,"Deleterious",35.13,30.1,944,651,1603,0.406113537117904,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["Expert, freq","UPN_Tr2_078",2,25469502,"CAGGCCCTTAGGGCCAGA","C","DNMT3A","ENST00000264709","frameshift_variant","tctggccctaagggcctg/|p.Ser417fs/c.1249_1265delTCTGGCCCTAAGGGCCT",1156,777,1939,0.40072202166065,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.96,"NA",1156,777,1939,0.40072202166065,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["454 validated, Expert, freq","UPN_Tr2_010",2,25469552,"T","TG","DNMT3A","ENST00000264709","frameshift_variant","ccc/cccC|p.Met406fs/c.1215dupC",4679,2117,4708,0.449660152931181,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.63,"NA",4666,2117,4695,0.450905218317359,13,0,13,0,0.0130772545233991,1,1,"Probably True (-5)"]
["Expert, prediction, bq","UPN_Tr2_014",2,25469633,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg379Cys/c.1135C>T",3012,1352,4380,0.308675799086758,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NA","NA","NO","NO","NO",2.471E-005,"NO","NO",-5.62,"Deleterious",35.44,34.19,0,0,0,"NA",3012,1352,4380,0.308675799086758,1,2,3,"Probably True (-6)"]
["Expert, prediction, bq","UPN_Tr2_064",2,25469927,"A","T","DNMT3A","ENST00000264709","missense_variant","gTc/gAc|p.Val372Asp/c.1115T>A",1328,660,2006,0.32901296111665,1,1,1,0,1,0,1,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.477,"Tolerated",23.42,34.86,1306,660,1984,0.332661290322581,22,0,22,0,0.000158174084314234,1,4,"Probably True (-2)"]
["454 validated, Expert, prediction, bq","UPN_Tr2_002",2,25470494,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp327*/c.980G>A",1967,416,2391,0.173985780008365,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",33.14,33.01,1953,416,2377,0.175010517458982,14,0,14,0,0.148430703587247,3,3,"Probably True (-4)"]
["Hotspot, 2nd Illumina, Expert, Cosmic, prediction, bq","UPN_Tr2_086",2,25470498,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg326Cys/c.976C>T",870,342,1220,0.280327868852459,0,1,0,1,1,0,1,1,5,"NO","NO","COSM4169721","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NA","NO","NO",-5.58,"Deleterious",31.16,30.15,870,342,1220,0.280327868852459,0,0,0,"NA",1,2,2,"Probably True (-5)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_058",2,198266494,"T","C","SF3B1","ENST00000335508","missense_variant","gAt/gGt|p.Asp781Gly/c.2342A>G",5857,974,6864,0.141899766899767,0,1,0,1,1,0,0,1,4,"NO","NO","COSM131554","haematopoietic_and_lymphoid_tissue, NS","4, 8","NO","NO","NO",8.237E-006,"NO","NO",-6.682,"Deleterious",35.16,34.92,5857,974,6864,0.141899766899767,0,0,0,"NA",1,1,1,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, bq","UPN_Tr2_054",2,198266611,"C","T","SF3B1","ENST00000335508","missense_variant","gGt/gAt|p.Gly742Asp/c.2225G>A",4017,50,4102,0.0121891760117016,0,0,0,0,1,0,0,1,2,"NO","NO","COSM145923","haematopoietic_and_lymphoid_tissue, kidney, lung","43, 1, 1","NO","NO","NO",1.649E-005,"NO","NO",-4.313,"Deleterious",32.48,33.64,0,0,0,"NA",4017,50,4102,0.0121891760117016,1,2,2,"Hotspot (-2)"]
["Hotspot, Expert, 454 validated; IonT_2 validated, Cosmic, bq","UPN_Tr2_009",2,198266611,"C","T","SF3B1","ENST00000335508","missense_variant","gGt/gAt|p.Gly742Asp/c.2225G>A",3203,1933,5163,0.374394731745109,0,0,0,1,0,0,0,0,1,"NO","NO","COSM145923","haematopoietic_and_lymphoid_tissue, kidney, lung","43, 1, 1","NO","NO","NO",1.649E-005,"NO","NO",-4.313,"Deleterious",33.63,34.68,0,0,0,"NA",3203,1933,5163,0.374394731745109,1,2,2,"Hotspot (-3)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_020",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",5205,3007,8217,0.365948643057077,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.59,35.35,0,0,0,"NA",5205,3007,8217,0.365948643057077,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_026",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",9105,5855,14980,0.390854472630174,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.62,35.3,0,0,0,"NA",9105,5855,14980,0.390854472630174,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_027",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",10944,5300,16255,0.326053521993233,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.52,35.34,0,0,0,"NA",10944,5300,16255,0.326053521993233,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_043",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",11689,1346,13058,0.103078572522592,0,1,0,1,1,0,0,1,4,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.33,34.68,0,0,0,"NA",11689,1346,13058,0.103078572522592,1,32,32,"Hotspot (-5)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_044",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3153,1224,4380,0.279452054794521,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.38,34.86,0,0,0,"NA",3153,1224,4380,0.279452054794521,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_030",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",7500,6128,13639,0.449299802038273,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.59,35.25,0,0,0,"NA",7500,6128,13639,0.449299802038273,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_031",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",6228,1702,7939,0.214384683209472,1,1,1,1,1,0,0,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.54,35.31,0,0,0,"NA",6228,1702,7939,0.214384683209472,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_047",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",13581,2332,15937,0.146326159252055,0,1,0,1,1,0,0,1,4,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.26,34.8,0,0,0,"NA",13581,2332,15937,0.146326159252055,1,32,32,"Hotspot (-5)"]
["Hotspot, 2nd Illumina, IonT_2 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_006",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",7277,3749,11049,0.339306724590461,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.44,35.19,0,0,0,"NA",7277,3749,11049,0.339306724590461,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_037",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",14581,3151,17757,0.177451146026919,1,1,0,1,1,0,0,1,5,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.58,35.35,0,0,0,"NA",14581,3151,17757,0.177451146026919,1,32,32,"Hotspot (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_039",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",7048,2112,9170,0.230316248636859,1,1,1,1,1,0,0,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.64,35.4,0,0,0,"NA",7048,2112,9170,0.230316248636859,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_054",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",8690,4951,13662,0.36239203630508,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.35,34.91,0,0,0,"NA",8690,4951,13662,0.36239203630508,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, IonT_2 validated, Cosmic, prediction, bq","UPN_Tr2_008",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",28967,4476,33486,0.133667801469271,0,1,0,1,1,0,0,1,4,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.43,35.18,0,0,0,"NA",28967,4476,33486,0.133667801469271,1,32,32,"Hotspot (-5)"]
["Hotspot, Expert, IonT_2 validated, Cosmic, prediction, bq","UPN_Tr2_010",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",12898,7695,20613,0.373308106534711,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.41,35.18,0,0,0,"NA",12898,7695,20613,0.373308106534711,1,32,32,"Hotspot (-7)"]
["Hotspot, 2nd Illumina, IonT_2 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_013",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3936,2980,6921,0.430573616529403,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.42,35.21,0,0,0,"NA",3936,2980,6921,0.430573616529403,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_092",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3115,2803,5923,0.473239912206652,1,1,0,1,1,0,1,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.49,35.17,0,0,0,"NA",3115,2803,5923,0.473239912206652,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_064",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3199,2320,5528,0.419681620839363,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.86,34.65,0,0,0,"NA",3199,2320,5528,0.419681620839363,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_065",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",4878,2653,7542,0.351763457968709,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.73,34.72,0,0,0,"NA",4878,2653,7542,0.351763457968709,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_071",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3801,1692,5500,0.307636363636364,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.79,34.82,0,0,0,"NA",3801,1692,5500,0.307636363636364,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_075",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",6904,2935,9851,0.297939295502995,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.8,34.76,0,0,0,"NA",6904,2935,9851,0.297939295502995,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_077",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",6646,4216,10874,0.387713812764392,1,1,1,1,1,0,1,1,7,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.91,34.88,0,0,0,"NA",6646,4216,10874,0.387713812764392,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_081",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",3840,2694,6541,0.411863629414463,1,1,0,1,1,0,1,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.93,34.76,0,0,0,"NA",3840,2694,6541,0.411863629414463,1,32,32,"Hotspot (-7)"]
["Hotspot","UPN_Tr2_084",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",11965,954,12931,0.0737761967365246,0,0,0,1,1,0,0,1,3,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.73,34.57,0,0,0,"NA",11965,954,12931,0.0737761967365246,1,32,32,"Hotspot (-4)"]
["Hotspot, 2nd Illumina, Expert, Cosmic, prediction, bq","UPN_Tr2_086",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",6790,1151,7957,0.144652507226342,1,1,0,1,1,0,0,1,5,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",34.87,34.7,0,0,0,"NA",6790,1151,7957,0.144652507226342,1,32,32,"Hotspot (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_094",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",7820,227,8055,0.0281812538795779,0,0,0,0,1,0,0,1,2,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.48,35.19,0,0,0,"NA",7820,227,8055,0.0281812538795779,1,32,32,"Hotspot (-2)"]
["Hotspot","UPN_Tr2_097",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",8437,484,8930,0.0541993281075028,0,0,0,1,1,0,0,1,3,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.49,35.37,0,0,0,"NA",8437,484,8930,0.0541993281075028,1,32,32,"Hotspot (-4)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_100",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",4443,2282,6730,0.339078751857355,1,1,0,1,1,0,1,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.47,35.32,0,0,0,"NA",4443,2282,6730,0.339078751857355,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_103",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",6360,1641,8006,0.20497127154634,1,1,0,1,1,0,0,1,5,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.5,35.33,0,0,0,"NA",6360,1641,8006,0.20497127154634,1,32,32,"Hotspot (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_105",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",5039,2676,7722,0.346542346542347,1,1,0,1,1,0,1,1,6,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.46,35.31,0,0,0,"NA",5039,2676,7722,0.346542346542347,1,32,32,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_109",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",8696,2668,11372,0.234611326064017,1,1,0,1,1,0,0,1,5,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.46,35.34,0,0,0,"NA",8696,2668,11372,0.234611326064017,1,32,32,"Hotspot (-6)"]
["Hotspot","UPN_Tr2_111",2,198266834,"T","C","SF3B1","ENST00000335508","missense_variant","Aaa/Gaa|p.Lys700Glu/c.2098A>G",10169,840,11022,0.0762112139357648,0,0,0,1,1,0,0,1,3,"NO",0,"COSM84677","breast, central_nervous_system, eye, haematopoietic_and_lymphoid_tissue, kidney, NS, oesophagus, pancreas, prostate","14, 2, 1, 395, 1, 515, 1, 13, 4","NO","NO","NO",0.0002306,"NO","NO",-3.819,"Deleterious",35.47,35.33,0,0,0,"NA",10169,840,11022,0.0762112139357648,1,32,32,"Hotspot (-4)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_050",2,198267359,"C","A","SF3B1","ENST00000335508","missense_variant","aaG/aaT|p.Lys666Asn/c.1998G>T",6315,3467,9808,0.353486949429038,1,1,0,0,1,1,1,1,6,"NO","NO","COSM131557","endometrium, haematopoietic_and_lymphoid_tissue, NS","1, 15, 28","NO","NO","NO","NA","NO","NO",-4.774,"Deleterious",35.23,33.56,4719,3461,8195,0.422330689444783,1596,6,1613,0.0037197768133912,2,1,2,"Hotspot (-8)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_019",2,198267359,"C","G","SF3B1","ENST00000335508","missense_variant","aaG/aaC|p.Lys666Asn/c.1998G>C",9789,116,9938,0.0116723686858523,0,0,0,0,1,0,0,0,1,0.0116,"NO","COSM132937","haematopoietic_and_lymphoid_tissue, liver","20, 1","NO","rs377023736","NO","NA","NO","NO",-4.774,"Deleterious",35.6,34.95,7595,116,7738,0.0149909537348152,2194,0,2200,0,2,1,2,"Hotspot (-2)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_101",2,198267360,"T","A","SF3B1","ENST00000335508","missense_variant","aAg/aTg|p.Lys666Met/c.1997A>T",7032,2313,9365,0.24698344901228,1,1,0,0,1,1,0,0,4,0.0116,"NO","COSM110698","haematopoietic_and_lymphoid_tissue",9,"NO","rs374250186","NO","NO","NO","NO",-5.729,"Deleterious",35.15,35.61,5452,2305,7775,0.296463022508039,1580,8,1590,0.0050314465408805,2,1,1,"Hotspot (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_045",2,198267361,"T","C","SF3B1","ENST00000335508","missense_variant","Aag/Gag|p.Lys666Glu/c.1996A>G",9272,1430,10751,0.133010882708585,0,1,0,0,1,1,0,0,3,"NO","NO","COSM110694","breast, haematopoietic_and_lymphoid_tissue, pancreas","1, 17, 1","NO","NO","NO","NO","NO","NO",-3.819,"Deleterious",34.05,35.51,7321,1427,8795,0.162251279135873,1951,3,1956,0.00153374233128834,2,1,1,"Hotspot (-5)"]
["Hotspot, Sanger other sample, 454 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_012",2,198267371,"G","C","SF3B1","ENST00000335508","missense_variant","caC/caG|p.His662Gln/c.1986C>G",4256,2332,6608,0.352905569007264,1,1,0,0,1,0,1,1,5,"NO","NO","COSM110692","haematopoietic_and_lymphoid_tissue, NS, prostate","30, 35, 1","NO","NO","NO","NA","NO","NO",-7.601,"Deleterious",34.58,35.49,3670,2332,6021,0.387311077894038,586,0,587,0,2,1,3,"Hotspot (-7)"]
["Hotspot, Sanger other sample, Expert, Cosmic, prediction, bq","UPN_Tr2_014",2,198267371,"G","T","SF3B1","ENST00000335508","missense_variant","caC/caA|p.His662Gln/c.1986C>A",9072,2344,11441,0.204877196049296,1,1,0,0,1,1,0,0,4,"NO","NO","COSM130416","haematopoietic_and_lymphoid_tissue",17,"NO","NO","NO","NA","NO","NO",-7.601,"Deleterious",35.11,35.11,7040,2342,9407,0.248963537791007,2032,2,2034,0.000983284169124877,2,2,3,"Hotspot (-6)"]
["Hotspot, Sanger other sample, Expert, Cosmic, prediction, bq","UPN_Tr2_053",2,198267371,"G","T","SF3B1","ENST00000335508","missense_variant","caC/caA|p.His662Gln/c.1986C>A",12066,2062,14177,0.145446850532553,0,1,0,0,1,1,0,0,3,"NO","NO","COSM130416","haematopoietic_and_lymphoid_tissue",17,"NO","NO","NO","NA","NO","NO",-7.601,"Deleterious",34.41,34.42,9562,2061,11670,0.176606683804627,2504,1,2507,0.000398883127243718,2,2,3,"Hotspot (-5)"]
["Hotspot, Expert, 454 validated, IonT_1 validated, Cosmic, prediction, bq","UPN_Tr2_015",2,198267373,"G","C","SF3B1","ENST00000335508","missense_variant","Cac/Gac|p.His662Asp/c.1984C>G",12268,3397,15710,0.216231699554424,1,1,0,0,1,1,0,0,4,"NO","NO","COSM131560","haematopoietic_and_lymphoid_tissue",10,"NO","NO","NO","NO","NO","NO",-8.551,"Deleterious",35,35.57,9707,3396,13144,0.258368837492392,2561,1,2566,0.00038971161340608,2,1,1,"Hotspot (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_069",2,198267481,"T","C","SF3B1","ENST00000335508","missense_variant","Aac/Gac|p.Asn626Asp/c.1876A>G",7270,4782,12092,0.395468078068144,1,1,1,1,1,1,1,1,8,"NO","NO","COSM131555","breast, haematopoietic_and_lymphoid_tissue, prostate","1, 2, 1","NO","NO","NO",8.236E-006,"NO","NO",-4.744,"Deleterious",34.55,33.29,355,196,568,0.345070422535211,6915,4586,11524,0.39795209996529,0.0448945305408115,1,1,"Hotspot (-9)"]
["Hotspot, Sanger other sample, 454 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_005",2,198267484,"G","A","SF3B1","ENST00000335508","missense_variant","Cgt/Tgt|p.Arg625Cys/c.1873C>T",1209,478,1693,0.282339043118724,1,1,1,1,1,0,1,1,7,"NO","NO","COSM110696","eye, haematopoietic_and_lymphoid_tissue, pancreas, salivary_gland, skin, urinary_tract","12, 11, 2, 1, 3, 1","NO","NO","NO",1.647E-005,"NO","NO",-7.491,"Deleterious",31.77,33.99,0,0,0,"NA",1209,478,1693,0.282339043118724,1,4,4,"Hotspot (-7)"]
["Hotspot, Sanger validated, 454 validated, IonT_1 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_035",2,198267484,"G","A","SF3B1","ENST00000335508","missense_variant","Cgt/Tgt|p.Arg625Cys/c.1873C>T",7423,2077,9524,0.218080638387232,1,1,1,1,1,0,0,1,6,"NO","NO","COSM110696","eye, haematopoietic_and_lymphoid_tissue, pancreas, salivary_gland, skin, urinary_tract","12, 11, 2, 1, 3, 1","NO","NO","NO",1.647E-005,"NO","NO",-7.491,"Deleterious",30.1,33.45,0,0,0,"NA",7423,2077,9524,0.218080638387232,1,4,4,"Hotspot (-7)"]
["Hotspot, Sanger other sample, 454 validated Expert, Cosmic, prediction, bq","UPN_Tr2_011",2,198267484,"G","A","SF3B1","ENST00000335508","missense_variant","Cgt/Tgt|p.Arg625Cys/c.1873C>T",12174,3176,15429,0.205846133903688,1,1,1,1,1,0,0,1,6,"NO","NO","COSM110696","eye, haematopoietic_and_lymphoid_tissue, pancreas, salivary_gland, skin, urinary_tract","12, 11, 2, 1, 3, 1","NO","NO","NO",1.647E-005,"NO","NO",-7.491,"Deleterious",31.38,33.78,16,0,16,0,12158,3176,15413,0.206059819632778,0.0561003386087418,4,4,"Hotspot (-6)"]
["Hotspot, Sanger other sample, Expert, Cosmic, prediction, bq","UPN_Tr2_095",2,198267484,"G","A","SF3B1","ENST00000335508","missense_variant","Cgt/Tgt|p.Arg625Cys/c.1873C>T",5514,3336,8878,0.37576030637531,1,1,0,1,1,0,1,1,6,"NO","NO","COSM110696","eye, haematopoietic_and_lymphoid_tissue, pancreas, salivary_gland, skin, urinary_tract","12, 11, 2, 1, 3, 1","NO","NO","NO",1.647E-005,"NO","NO",-7.491,"Deleterious",30.02,34.4,0,0,0,"NA",5514,3336,8878,0.37576030637531,1,4,4,"Hotspot (-7)"]
["Hotspot, Sanger validated, 454 validated, IonT_1 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_024",2,198267491,"C","A","SF3B1","ENST00000335508","missense_variant","gaG/gaT|p.Glu622Asp/c.1866G>T",3950,1186,5145,0.230515063168124,1,1,1,1,1,0,0,1,6,"NO","NO","COSM110693","haematopoietic_and_lymphoid_tissue",30,"NO","NO","NO","NO","NO","NO",-2.737,"Deleterious",34.95,35.09,0,0,0,"NA",3950,1186,5145,0.230515063168124,1,1,1,"Hotspot (-8)"]
["Hotspot","UPN_Tr2_047",2,198267501,"T","A","SF3B1","ENST00000335508","missense_variant","aAc/aTc|p.Asn619Ile/c.1856A>T",1044,29,1081,0.0268270120259019,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.979,"Deleterious",35.42,34.55,0,0,0,"NA",1044,29,1081,0.0268270120259019,1,1,1,"Hotspot (-3)"]
["Hotspot","UPN_Tr2_048",2,198267705,"C","T","SF3B1","ENST00000335508","missense_variant","Gaa/Aaa|p.Glu592Lys/c.1774G>A",745,30,777,0.0386100386100386,0,0,0,0,1,0,0,1,2,"NO","NO","COSM132936","haematopoietic_and_lymphoid_tissue",6,"NO","NO","NO","NO","NO","NO",-3.517,"Deleterious",33.45,35,0,0,0,"NA",745,30,777,0.0386100386100386,1,1,1,"Hotspot (-4)"]
["Expert, freq","UPN_Tr2_067",4,106155606,"T","TA","TET2","ENST00000380013","frameshift_variant","aac/aaAc|p.Asn170fs/c.509dupA",58678,16151,58895,0.2742338059258,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.77,"NA",29643,8227,29766,0.276389168850366,29035,7924,29129,0.272031309004772,0.346217393216148,1,1,"Probably True (-5)"]
["454 validated, Expert, freq","UPN_Tr2_005",4,106156426,"AC","A","TET2","ENST00000380013","frameshift_variant","aca/|p.Thr443fs/c.1328delC",1886,3408,5310,0.64180790960452,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.47,"NA",934,1751,2695,0.649721706864564,952,1657,2615,0.633652007648184,0.196645755722469,1,1,"Probably True (-5)"]
["Expert, bq, freq","UPN_Tr2_028",4,106156675,"C","T","TET2","ENST00000380013","stop_gained","Cag/Tag|p.Gln526*/c.1576C>T",11006,5111,16156,0.316353057687546,0,1,0,0,1,1,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.28,35.63,3233,2,3255,0.000614439324116743,7773,5109,12901,0.396015812727696,2,1,1,"Probably True (-2)"]
["Expert, bq, freq","UPN_Tr2_049",4,106156795,"G","T","TET2","ENST00000380013","stop_gained","Gaa/Taa|p.Glu566*/c.1696G>T",4482,7629,12223,0.624151190378794,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.89,32.67,2219,3747,6053,0.619031885015695,2263,3882,6170,0.629173419773096,0.678843891997176,1,1,"Probably True (-5)"]
["2nd Illumina, 454 validated, Expert, freq","UPN_Tr2_001",4,106157105,"CA","C","TET2","ENST00000380013","frameshift_variant","aaa/|p.Ala671fs/c.2010delA",19432,7460,26997,0.276326999296218,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.08,"NA",9762,3558,13368,0.266157989228007,9670,3902,13629,0.286301269352117,0.000189874675523221,1,1,"Probably True (-5)"]
["Expert, freq","UPN_Tr2_054",4,106157182,"AT","A","TET2","ENST00000380013","frameshift_variant","atg/|p.Met695fs/c.2084delT",25645,4788,30647,0.15623062616243,1,1,0,1,1,1,0,0,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.2,"NA",2150,4712,6908,0.682107701215982,23495,76,23739,0.00320148279202999,2,1,1,"Probably True (-3)"]
["Inspected, 454 validated","UPN_Tr2_035",4,106157219,"CTTCAGAGACTGAGCCA","C","TET2","ENST00000380013","frameshift_variant","tcagagactgagccattt/|p.Ser708fs/c.2123_2138delCAGAGACTGAGCCATT",21150,1183,22434,0.0527324596594455,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.51,"NA",10640,596,11287,0.0528041109240719,10510,587,11147,0.0526599084955593,0.976168241130201,2,2,"Probably True (-4)"]
["Inspected, 454 validated","UPN_Tr2_011",4,106157219,"CTTCAGAGACTGAGCCA","C","TET2","ENST00000380013","frameshift_variant","tcagagactgagccattt/|p.Ser708fs/c.2123_2138delCAGAGACTGAGCCATT",21773,2444,24316,0.100509952294785,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.32,"NA",10969,1232,12253,0.100546804864115,10804,1212,12063,0.100472519273812,0.982981823065461,2,2,"Probably True (-5)"]
["454 validated, Expert, freq","UPN_Tr2_089",4,106157235,"AT","A","TET2","ENST00000380013","frameshift_variant","tca/|p.Ser714fs/c.2140delT",6167,7624,13845,0.550668111231492,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.68,"NA",3097,3828,6954,0.550474547023296,3070,3796,6891,0.550863445073284,1,1,1,"Probably True (-5)"]
["Expert, bq, freq","UPN_Tr2_068",4,106157342,"T","A","TET2","ENST00000380013","stop_gained","tTa/tAa|p.Leu748*/c.2243T>A",25165,11153,36394,0.306451612903226,1,1,0,0,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.84,35.09,14511,11147,25711,0.433549842479872,10654,6,10683,0.0005616399887672,2,1,1,"Probably True (-3)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_071",4,106157573,"C","G","TET2","ENST00000380013","stop_gained","tCa/tGa|p.Ser825*/c.2474C>G",27182,10347,37753,0.274070934760151,0,1,1,1,1,1,0,1,6,"NO","NO","COSM4383851, COSM87104","haematopoietic_and_lymphoid_tissue",5,"NO","NO","NO","NO","NO","NO","NA","NA",33.08,33.81,13701,5182,19017,0.272493032549824,13481,5165,18736,0.275672502134927,0.579262785848277,1,1,"Probably True (-5)"]
["Expert, freq","UPN_Tr2_025",4,106157679,"AAACTTGCATC","A","TET2","ENST00000380013","frameshift_variant","aacttgcatcac/|p.Asn861fs/c.2582_2591delACTTGCATCA",17963,11198,29246,0.382889967858852,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.67,"NA",8943,5730,14708,0.389583899918412,9020,5468,14538,0.37611776035218,0.0221515570412606,1,1,"Probably True (-5)"]
["Expert, bq, freq","UPN_Tr2_048",4,106157806,"A","T","TET2","ENST00000380013","missense_variant","Aac/Tac|p.Asn903Tyr/c.2707A>T",446,116,563,0.206039076376554,1,1,1,0,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.702,"Tolerated",35.48,34.53,0,115,115,1,446,1,448,0.00223214285714286,2,1,1,"Probably True (-3)"]
["Expert, bq, freq","UPN_Tr2_048",4,106157810,"A","G","TET2","ENST00000380013","missense_variant","cAa/cGa|p.Gln904Arg/c.2711A>G",444,115,563,0.204262877442274,1,1,1,0,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.9,"Tolerated",35.71,34.76,0,114,115,0.991304347826087,444,1,448,0.00223214285714286,2,1,1,"Probably True (-3)"]
["Expert, bq, freq","UPN_Tr2_048",4,106157848,"C","T","TET2","ENST00000380013","stop_gained","Caa/Taa|p.Gln917*/c.2749C>T",600,214,818,0.26161369193154,1,1,1,0,1,1,1,1,7,"NO","NO","COSM5487353, COSM5487354","Something is odd...",0,"NO","NO","NO","NO","NO","NO","NA","NA",28.31,32.77,0,114,115,0.991304347826087,600,100,703,0.142247510668563,1.44933265929636E-079,1,1,"Probably True (-3)"]
["2nd Illumina, 454 validated, IonT_1 validated, Expert","UPN_Tr2_004",4,106157878,"GT","G","TET2","ENST00000380013","frameshift_variant","ttt/|p.Pro929fs/c.2784delT",1527,1018,2557,0.398122800156433,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.89,"NA",765,506,1277,0.396241190289742,762,512,1280,0.4,0.871433480237684,1,1,"Probably True (-5)"]
["inspected","UPN_Tr2_044",4,106157929,"A","T","TET2","ENST00000380013","stop_gained","Aag/Tag|p.Lys944*/c.2830A>T",1128,153,1286,0.118973561430793,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.51,34.4,0,0,0,"NA",1128,153,1286,0.118973561430793,1,1,1,"Probably True (-4)"]
["Inspected, 454 validated","UPN_Tr2_010",4,106158201,"G","GT","TET2","ENST00000380013","frameshift_variant","cac/Tcac|p.His1036fs/c.3105dupT",40385,3530,40457,0.0872531329559779,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.36,"NA",20385,1792,20409,0.0878044000195992,20000,1738,20048,0.0866919393455706,0.75205635183741,1,1,"Probably True (-4)"]
["Expert, freq","UPN_Tr2_045",4,106164036,"T","TA","TET2","ENST00000380013","frameshift_variant","act/aAct|p.Thr1183fs/c.3547dupA",40645,11235,40854,0.275003671611103,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.38,"NA",21010,6183,21140,0.29247871333964,19635,5052,19714,0.256264583544689,3.47840088107664E-010,1,1,"Probably True (-5)"]
["Expert, bq, prediction","UPN_Tr2_077",4,106164079,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys1197Glu/c.3589A>G",32817,11460,44527,0.257371931636984,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.647,"Deleterious",32.35,32.56,16570,5769,22418,0.257337853510572,16247,5691,22109,0.257406486046406,0.786183075860553,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_041",4,106164754,"A","T","TET2","ENST00000380013","stop_gained","Aag/Tag|p.Lys1208*/c.3622A>T",152,29,182,0.159340659340659,1,1,0,1,1,0,0,1,5,"NO","NO","COSM211716","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",34.7,36,152,29,182,0.159340659340659,0,0,0,"NA",1,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_095",4,106180810,"AC","A","TET2","ENST00000380013","frameshift_variant","acc/|p.Cys1281fs/c.3840delC",7517,341,7865,0.0433566433566434,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.27,"NA",7517,341,7865,0.0433566433566434,0,0,0,"NA",1,1,1,"Probably True (-1)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_034",4,106180834,"G","A","TET2","ENST00000380013","missense_variant","Ggt/Agt|p.Gly1288Ser/c.3862G>A",2523,584,3123,0.186999679795069,1,1,0,1,1,0,0,1,5,"NO","NO","COSM110780","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO",-5.429,"Deleterious",34.97,34.34,2523,584,3123,0.186999679795069,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_064",4,106180835,"G","T","TET2","ENST00000380013","missense_variant","gGt/gTt|p.Gly1288Val/c.3863G>T",1666,1083,2755,0.393103448275862,1,1,1,1,1,0,1,1,7,"NO","NO","COSM1716167","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO",-8.077,"Deleterious",33.87,34.29,1666,1083,2755,0.393103448275862,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_048",4,106180874,"C","T","TET2","ENST00000380013","missense_variant","gCc/gTc|p.Ala1301Val/c.3902C>T",307,54,362,0.149171270718232,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.47,"Deleterious",31.12,32.65,155,27,182,0.148351648351648,152,27,180,0.15,1,2,2,"Probably True (-6)"]
["Expert, bq, prediction","UPN_Tr2_078",4,106180891,"A","G","TET2","ENST00000380013","missense_variant","Agg/Ggg|p.Arg1307Gly/c.3919A>G",14085,4613,18783,0.24559442048661,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.222,"Deleterious",32.89,31.25,7113,2309,9444,0.244493858534519,6972,2304,9339,0.246707356247992,0.599011324383065,1,1,"Probably True (-6)"]
["Expert, bq, prediction","UPN_Tr2_092",4,106190776,"G","A","TET2","ENST00000380013","missense_variant","Gaa/Aaa|p.Glu1352Lys/c.4054G>A",928,1000,1935,0.516795865633075,1,1,0,1,1,0,1,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.82,"Deleterious",35.6,35.84,928,1000,1935,0.516795865633075,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["Expert, Cosmic, bq","UPN_Tr2_030",4,106190797,"C","T","TET2","ENST00000380013","missense_variant","Cgt/Tgt|p.Arg1359Cys/c.4075C>T",627,4768,5400,0.882962962962963,1,1,1,1,1,0,1,1,7,"NO","NO","COSM41649","cervix, haematopoietic_and_lymphoid_tissue","1, 5","NO","NO","NO","NO","NO","NO",-7.245,"Deleterious",35.06,35.23,627,4768,5400,0.882962962962963,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_103",4,106190860,"C","T","TET2","ENST00000380013","missense_variant","Cat/Tat|p.His1380Tyr/c.4138C>T",6837,1005,7856,0.127927698574338,1,1,0,1,1,1,0,1,6,"NO","NO","COSM87161","haematopoietic_and_lymphoid_tissue",13,"NO","NO","NO",7.586E-005,"NO","NO",-5.713,"Deleterious",33.02,35.16,3436,505,3946,0.127977698935631,3401,500,3910,0.127877237851662,1,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_053",4,106193874,"GTAC","G","TET2","ENST00000380013","disruptive_inframe_deletion","gtactg/gtg|p.Leu1447del/c.4338_4340delACT",8722,1587,10352,0.15330370942813,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-11.277,"Deleterious",33.47,"NA",0,0,0,"NA",8722,1587,10352,0.15330370942813,1,1,1,"Probably True (-6)"]
["Expert, freq","UPN_Tr2_071",4,106193926,"CT","C","TET2","ENST00000380013","frameshift_variant","tgc/|p.Cys1464fs/c.4390delT",5340,820,6194,0.132386180174362,1,1,0,1,0,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.09,"NA",2556,818,3397,0.24080070650574,2784,2,2797,0.000715051841258491,2,1,1,"Probably True (-2)"]
["Expert, freq; part of complex variant","UPN_Tr2_071",4,106193929,"G","A","TET2","ENST00000380013","missense_variant","tGc/tAc|p.Cys1464Tyr/c.4391G>A",5354,825,6194,0.133193412980304,1,1,0,0,0,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.155,"Deleterious",34.76,33.87,2564,822,3397,0.241978216073006,2790,3,2797,0.00107257776188774,2,1,1,"Probably True (-2)"]
["inspected","UPN_Tr2_026",4,106194073,"C","T","TET2","ENST00000380013","missense_variant","gCa/gTa|p.Ala1512Val/c.4535C>T",10452,1052,11520,0.0913194444444444,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.626,"Tolerated",34.38,34.84,0,0,0,"NA",10452,1052,11520,0.0913194444444444,1,1,1,"Probably True (-1)"]
["Expert, freq, no SNP database","UPN_Tr2_026",4,106196328,"CAG","C","TET2","ENST00000380013","frameshift_variant","gag/|p.Glu1555fs/c.4664_4665delAG",4929,4996,9955,0.501858362631843,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.13,"NA",2486,2445,4940,0.494939271255061,2443,2551,5015,0.508673978065803,0.137409249372141,1,1,"Probably True (-5)"]
["Expert, bq, no SNP database","UPN_Tr2_047",4,106196645,"A","G","TET2","ENST00000380013","missense_variant","Agg/Ggg|p.Arg1660Gly/c.4978A>G",15877,15710,31750,0.494803149606299,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.308,"Tolerated",33.43,32.21,7877,7779,15738,0.494281357224552,8000,7931,16012,0.495316012990257,0.865954080066896,1,1,"Probably True (-5)"]
["inspected","UPN_Tr2_044",4,106197230,"C","A","TET2","ENST00000380013","missense_variant","Ctg/Atg|p.Leu1855Met/c.5563C>A",1224,189,1414,0.133663366336634,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.161,"Tolerated",33.72,32.8,604,94,699,0.13447782546495,620,95,715,0.132867132867133,0.937819346095772,1,1,"Probably True (-3)"]
["454 validated, IonT_1 validated, Expert, bq, prediction","UPN_Tr2_015",4,106197302,"G","A","TET2","ENST00000380013","missense_variant","Gag/Aag|p.Glu1879Lys/c.5635G>A",17293,5141,22454,0.228956978712033,1,1,0,0,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.735,"Deleterious",35.57,35.8,13380,5021,18417,0.272628549709508,3913,120,4037,0.0297250433490216,2,1,1,"Probably True (-3)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_026",4,106197308,"C","T","TET2","ENST00000380013","missense_variant","Cat/Tat|p.His1881Tyr/c.5641C>T",16869,3565,20453,0.174302058377744,1,1,0,0,1,1,0,0,4,"NO","NO","COSM4383970","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-5.573,"Deleterious",35.67,35.53,12994,3563,16576,0.214949324324324,3875,2,3877,0.000515862780500387,2,1,1,"Probably True (-3)"]
["2nd Illumina, 454 validated Expert, prediction, bq","UPN_Tr2_013",7,148506402,"C","A","EZH2","ENST00000320356","missense_variant","Gtt/Ttt|p.Val704Phe/c.2110G>T",3513,2462,5988,0.411155644622578,0,0,0,1,0,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.002,"Deleterious",34.86,35.28,3513,2462,5988,0.411155644622578,0,0,0,"NA",1,1,1,"Probably True (-1)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_049",7,148506443,"C","T","EZH2","ENST00000320356","missense_variant","cGt/cAt|p.Arg690His/c.2069G>A",5787,19118,25003,0.764628244610647,1,1,1,1,1,1,1,1,8,"NO","NO","COSM52980","haematopoietic_and_lymphoid_tissue",15,"NO","NO","NO","NO","NO","NO",-4.164,"Deleterious",30.96,32.97,2878,9546,12502,0.763557830747081,2909,9572,12501,0.765698744100472,0.798678341434081,1,1,"Probably True (-6)"]
["Expert, prediction, bq","UPN_Tr2_082",7,148507464,"C","G","EZH2","ENST00000320356","missense_variant","Gat/Cat|p.Asp664His/c.1990G>C",16410,5060,21517,0.235162894455547,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.874,"Deleterious",35.1,35.02,16410,5060,21517,0.235162894455547,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["Expert, bq, prediction","UPN_Tr2_017",7,148512074,"C","A","EZH2","ENST00000320356","missense_variant","tGt/tTt|p.Cys535Phe/c.1604G>T",6658,5185,11907,0.435458133870832,1,1,0,1,1,1,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-9.203,"Deleterious",32.83,33.16,3364,2710,6101,0.444189477134896,3294,2475,5806,0.426283155356528,0.0613072899184914,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_070",7,148512610,"G","GT","EZH2","ENST00000320356","frameshift_variant","ata/ataA|p.Gln512fs/c.1533dupA",10071,669,10111,0.0661655622589259,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.85,"NA",10071,669,10111,0.0661655622589259,0,0,0,"NA",1,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_034",7,148514992,"TTCTTC","T","EZH2","ENST00000320356","frameshift_variant","gagaagaaa/|p.Lys405fs/c.1212_1216delGAAGA",1561,209,1781,0.11734980348119,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.17,"NA",1561,209,1781,0.11734980348119,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["inspected, no strandbias","UPN_Tr2_048",7,148515069,"TG","T","EZH2","ENST00000320356","frameshift_variant","tca/|p.Ser380fs/c.1139delC",1172,67,1245,0.0538152610441767,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.28,"NA",587,34,626,0.0543130990415335,585,33,619,0.0533117932148627,1,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_110",7,148516754,"A","T","EZH2","ENST00000320356","stop_gained","taT/taA|p.Tyr311*/c.933T>A",3216,558,3782,0.147540983606557,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.16,35.5,3216,558,3782,0.147540983606557,0,0,0,"NA",1,2,2,"Probably True (-4)"]
["Hotspot, Sanger validated, 454 validated, IonT_1 validated, Expert, Cosmic, bq","UPN_Tr2_040",7,148523591,"G","A","EZH2","ENST00000320356","stop_gained","Cga/Tga|p.Arg288*/c.862C>T",8896,8719,17663,0.493630753552624,1,1,1,1,1,1,1,1,8,"NO","NO","COSM1000721","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO","NA","NA",33.39,32.54,4500,4503,9021,0.499168606584636,4396,4216,8642,0.487850034714187,0.160972724404882,2,2,"Probably True (-5)"]
["Expert, bq, freq","UPN_Tr2_056",7,148524330,"A","T","EZH2","ENST00000320356","missense_variant","ttT/ttA|p.Phe218Leu/c.654T>A",85,22,109,0.201834862385321,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.65,"Deleterious",33.71,33.82,43,11,55,0.2,42,11,54,0.203703703703704,1,1,1,"Probably True (-5)"]
["inspected","UPN_Tr2_098",7,148525847,"C","A","EZH2","ENST00000320356","stop_gained","Gag/Tag|p.Glu204*/c.610G>T",5266,997,6286,0.158606426980592,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.65,35.72,5266,997,6286,0.158606426980592,0,0,0,"NA",1,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_085",7,148526867,"A","G","EZH2","ENST00000320356","missense_variant","aTt/aCt|p.Ile146Thr/c.437T>C",18770,3689,22477,0.164123326066646,0,1,0,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.135,"Deleterious",35.32,34.73,18770,3689,22477,0.164123326066646,0,0,0,"NA",1,1,1,"Probably True (-4)"]
["Hotspot, Sanger other sample, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_097",9,5073770,"G","T","JAK2","ENST00000381652","missense_variant","Gtc/Ttc|p.Val617Phe/c.1849G>T",7591,3798,11403,0.333070244672455,1,1,0,1,1,1,1,1,7,0.0233,"NO","COSM12600","central_nervous_system, haematopoietic_and_lymphoid_tissue, lung","1, 37620, 3","NO","rs77375493","YES",0.0006919,"NO","NO",-3.94,"Deleterious",31.45,34.99,3776,1909,5693,0.335324082206218,3815,1889,5710,0.330823117338004,0.605357231301082,1,1,"Hotspot (-9)"]
["inspected","UPN_Tr2_075",11,119149002,"T","C","CBL","ENST00000264033","missense_variant","Tgg/Cgg|p.Trp408Arg/c.1222T>C",15640,878,16571,0.0529841288998853,0,0,0,0,1,1,0,0,2,"NO","NO","COSM34060","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO",-13.074,"Deleterious",35.32,34.55,6822,853,7702,0.110750454427421,8818,25,8869,0.00281880708084339,2,1,1,"Probably True (-2)"]
["inspected","UPN_Tr2_027",11,119149280,"G","A","CBL","ENST00000264033","missense_variant","Gtg/Atg|p.Val430Met/c.1288G>A",12737,6490,19351,0.335383184331559,1,1,1,1,1,1,1,1,8,"NO","NO","COSM5492878","Something is odd...",0,"NO","NO","NO","NO","NO","NO",-2.119,"Tolerated",32.93,32.81,6465,3379,9860,0.342697768762677,6272,3111,9491,0.327784216626278,0.0875331507666365,1,1,"Probably True (-5)"]
["inspected","UPN_Tr2_028",12,12006472,"T","TA","ETV6","ENST00000396373","frameshift_variant","ctg/Actg|p.Leu148fs/c.441dupA",22701,2711,22788,0.118966122520625,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.38,"NA",11435,1334,11485,0.116151501959077,11266,1377,11303,0.121826063876847,0.255165658818429,2,2,"Probably True (-5)"]
["2nd Illumina, Expert, freq","UPN_Tr2_083",12,12022491,"G","GC","ETV6","ENST00000396373","frameshift_variant","ctc/cCtc|p.Leu201fs/c.601dupC",5676,1577,5712,0.276085434173669,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.82,"NA",0,0,0,"NA",5676,1577,5712,0.276085434173669,1,1,1,"Probably True (-5)"]
["Expert, prediction, bq","UPN_Tr2_017",12,12037403,"T","C","ETV6","ENST00000396373","missense_variant","gTc/gCc|p.Val345Ala/c.1034T>C",2994,2502,5506,0.454413367235743,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.058,"Deleterious",35.56,35.19,2994,2502,5506,0.454413367235743,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["inspected","UPN_Tr2_098",12,12038902,"C","T","ETV6","ENST00000396373","missense_variant","Cgc/Tgc|p.Arg399Cys/c.1195C>T",3737,327,4071,0.0803242446573323,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.975,"Deleterious",34.74,35.07,3737,327,4071,0.0803242446573323,0,0,0,"NA",1,1,1,"Probably True (-2)"]
["inspected","UPN_Tr2_048",12,25398263,"A","G","KRAS","ENST00000256078","missense_variant","tTg/tCg|p.Leu19Ser/c.56T>C",122,20,142,0.140845070422535,0,1,0,1,1,0,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.979,"Deleterious",35.43,32.6,122,20,142,0.140845070422535,0,0,0,"NA",1,1,1,"Probably True (-4)"]
["Hotspot","UPN_Tr2_025",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",19804,573,20412,0.028071722516167,0,0,0,0,1,1,0,1,3,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",31.66,32.7,9957,285,10257,0.0277859023106171,9847,288,10155,0.0283604135893648,0.799493307727919,7,7,"Hotspot (-2)"]
["Hotspot, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_045",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",15778,3523,19370,0.181879194630872,1,1,0,1,1,1,0,1,6,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",30.71,32.56,7953,1779,9759,0.182293267752844,7825,1744,9611,0.181458745187806,0.925774158121779,7,7,"Hotspot (-7)"]
["Hotspot, 454 validated Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_009",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",21641,12877,34625,0.371898916967509,1,1,1,1,1,1,1,1,8,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",31.74,32.95,10876,6457,17384,0.37143350207087,10765,6420,17241,0.372368192100226,0.841226342080042,7,7,"Hotspot (-7)"]
["Hotspot, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_079",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",10981,2167,13213,0.164005146446681,1,1,0,1,1,1,0,1,6,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",29.91,32.15,5532,1079,6625,0.162867924528302,5449,1088,6588,0.16514875531269,0.621633034557428,7,7,"Hotspot (-7)"]
["Hotspot, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_082",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",13978,2440,16511,0.147780267700321,1,1,0,1,1,1,0,1,6,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",29.97,32,7072,1223,8335,0.146730653869226,6906,1217,8176,0.148850293542074,0.676779713942801,7,7,"Hotspot (-7)"]
["Hotspot, Expert, dbSNP flag, Cosmic, prediction, bq","UPN_Tr2_110",15,90631934,"C","T","IDH2","ENST00000330062","missense_variant","cGg/cAg|p.Arg140Gln/c.419G>A",13168,1924,15125,0.127206611570248,1,1,0,1,1,1,0,1,6,"NO","NO","COSM41590","haematopoietic_and_lymphoid_tissue",489,"NO","rs121913502","YES",0.0001071,"NO","NO",-3.75,"Deleterious",30.25,33.93,6602,963,7580,0.127044854881266,6566,961,7545,0.127369118621604,0.961069268837321,7,7,"Hotspot (-7)"]
["Hotspot","UPN_Tr2_061",15,90631935,"G","A","IDH2","ENST00000330062","missense_variant","Cgg/Tgg|p.Arg140Trp/c.418C>T",24609,1443,26188,0.0551015732396518,0,0,0,0,1,1,0,1,3,"NO","NO","COSM41877","haematopoietic_and_lymphoid_tissue, large_intestine","10, 2","NO","NO","NO","NO","NO","NO",-7.5,"Deleterious",32.28,30.88,12397,722,13147,0.0549174716665399,12212,721,13041,0.0552871712292002,0.807445249497738,1,1,"Hotspot (-4)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_056",17,7579314,"T","G","TP53","ENST00000269305","missense_variant","Acg/Ccg|p.Thr125Pro/c.373A>C",385,3670,4074,0.900834560628375,0,1,0,0,1,0,0,1,3,"NO","NO","COSM1646886, COSM707863, COSM3970385, COSM707862, COSM45368","central_nervous_system, lung","5, 6","NO","NO","NO","NO","NO","NO",-5.478,"Deleterious",34.95,34.95,373,3670,4059,0.904163587090416,12,0,15,0,4.58681043533836E-013,1,1,"Probably True (-1)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_092",17,7579395,"G","A","TP53","ENST00000269305","missense_variant","Cct/Tct|p.Pro98Ser/c.292C>T",853,723,1580,0.457594936708861,1,1,0,1,1,0,1,1,6,"NO","NO","COSM12296","haematopoietic_and_lymphoid_tissue, oesophagus, skin","1, 1, 1","NO","NO","NO","NO","NO","NO",-6.482,"Deleterious",34.83,32.91,853,723,1580,0.457594936708861,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["Expert, prediction","UPN_Tr2_028",17,74732935,"CGGCGGCTGTGGTGTGAGTCCGGGG","C","SRSF2","ENST00000392485","disruptive_inframe_deletion","cccccggactcacaccacagccgccgg/cgg|p.Pro95_Arg102del/c.284_307delCCCCGGACTCACACCACAGCCGCC",2544,1243,3801,0.327019205472244,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO",1.693E-005,"NO","NO",-10.625,"Deleterious",34.27,"NA",1283,1190,2481,0.479645304312777,1261,53,1320,0.0401515151515152,1.39100687404897E-202,2,2,"Hotspot (-9)"]
["Expert, prediction","UPN_Tr2_036",17,74732935,"CGGCGGCTGTGGTGTGAGTCCGGGG","C","SRSF2","ENST00000392485","disruptive_inframe_deletion","cccccggactcacaccacagccgccgg/cgg|p.Pro95_Arg102del/c.284_307delCCCCGGACTCACACCACAGCCGCC",2906,343,3256,0.10534398034398,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO",1.693E-005,"NO","NO",-10.625,"Deleterious",34.08,"NA",1475,337,1816,0.18557268722467,1431,6,1440,0.00416666666666667,3.16541566791131E-082,2,2,"Hotspot (-8)"]
["Expert, prediction","UPN_Tr2_079",17,74732944,"TGGTGTGAGTCCGGGG","T","SRSF2","ENST00000392485","disruptive_inframe_deletion","cccccggactcacaccac/cac|p.Pro95_His99del/c.284_298delCCCCGGACTCACACC",129,76,205,0.370731707317073,1,1,0,1,1,1,1,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-10.124,"Deleterious",34.53,"NA",65,39,104,0.375,64,37,101,0.366336633663366,1,1,1,"Probably True (-6)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_025",17,74732959,"G","A","SRSF2","ENST00000392485","missense_variant","cCc/cTc|p.Pro95Leu/c.284C>T",4930,2853,7794,0.366050808314088,1,1,1,1,1,1,1,1,8,"NO","NO","COSM146288","haematopoietic_and_lymphoid_tissue",93,"NO","NO","NO","NO","NO","NO",-5.208,"Deleterious",34.42,30.14,2480,1439,3922,0.366904640489546,2450,1414,3872,0.365185950413223,0.925034684843181,2,13,"Hotspot (-9)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_044",17,74732959,"G","A","SRSF2","ENST00000392485","missense_variant","cCc/cTc|p.Pro95Leu/c.284C>T",3368,66,3436,0.0192083818393481,0,0,0,0,1,1,0,1,3,"NO","NO","COSM146288","haematopoietic_and_lymphoid_tissue",93,"NO","NO","NO","NO","NO","NO",-5.208,"Deleterious",34.41,31.7,1700,32,1733,0.018465089440277,1668,34,1703,0.0199647680563711,0.804153151135408,2,13,"Hotspot (-2)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_021",17,74732959,"G","C","SRSF2","ENST00000392485","missense_variant","cCc/cGc|p.Pro95Arg/c.284C>G",2636,1086,3735,0.290763052208835,1,1,1,1,1,1,1,1,8,"NO","NO","COSM211661","haematopoietic_and_lymphoid_tissue",55,"NO","NO","NO","NO","NO","NO",-4.575,"Deleterious",34.25,34.59,1326,545,1879,0.290047897817988,1310,541,1856,0.291487068965517,0.971237443665191,5,13,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_052",17,74732959,"G","C","SRSF2","ENST00000392485","missense_variant","cCc/cGc|p.Pro95Arg/c.284C>G",3845,4820,8687,0.554852077817428,1,1,1,1,1,1,1,1,8,"NO","NO","COSM211661","haematopoietic_and_lymphoid_tissue",55,"NO","NO","NO","NO","NO","NO",-4.575,"Deleterious",34.32,34.24,1929,2434,4372,0.55672461116194,1916,2386,4315,0.552954808806489,0.762146675882948,5,13,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_090",17,74732959,"G","C","SRSF2","ENST00000392485","missense_variant","cCc/cGc|p.Pro95Arg/c.284C>G",3034,375,3414,0.109841827768014,0,1,0,1,1,1,0,1,5,"NO","NO","COSM211661","haematopoietic_and_lymphoid_tissue",55,"NO","NO","NO","NO","NO","NO",-4.575,"Deleterious",33.73,33.86,1524,188,1714,0.109684947491249,1510,187,1700,0.11,1,5,13,"Hotspot (-6)"]
["Hotspot, inspected","UPN_Tr2_097",17,74732959,"G","C","SRSF2","ENST00000392485","missense_variant","cCc/cGc|p.Pro95Arg/c.284C>G",4036,111,4175,0.0265868263473054,0,0,0,0,1,1,0,1,3,"NO","NO","COSM211661","haematopoietic_and_lymphoid_tissue",55,"NO","NO","NO","NO","NO","NO",-4.575,"Deleterious",33.79,33.31,2030,56,2099,0.0266793711291091,2006,55,2076,0.0264932562620424,1,5,13,"Hotspot (-2)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_110",17,74732959,"G","C","SRSF2","ENST00000392485","missense_variant","cCc/cGc|p.Pro95Arg/c.284C>G",3709,1043,4758,0.219209751996637,1,1,0,1,1,1,1,1,7,"NO","NO","COSM211661","haematopoietic_and_lymphoid_tissue",55,"NO","NO","NO","NO","NO","NO",-4.575,"Deleterious",33.65,34.03,1864,524,2391,0.219155165202844,1845,519,2367,0.219264892268695,1,5,13,"Hotspot (-7)"]
["Expert, IonT_2 validated, prediction, freq","UPN_Tr2_003",17,74732959,"G","GGGC","SRSF2","ENST00000392485","inframe_insertion","ccc/cGCCcc|p.Arg94dup/c.281_283dupGCC",448,85,448,0.189732142857143,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.479,"Deleterious",35.17,"NA",225,42,225,0.186666666666667,223,43,223,0.192825112107623,0.906347155748649,1,13,"Probably True (-5)"]
["Hotspot, Expert, IonT_2 validated, Cosmic, prediction, bq","UPN_Tr2_002",17,74732959,"G","T","SRSF2","ENST00000392485","missense_variant","cCc/cAc|p.Pro95His/c.284C>A",2154,306,2460,0.124390243902439,1,1,0,1,1,1,0,1,6,"NO","NO","COSM211504","haematopoietic_and_lymphoid_tissue",147,"NO","NO","NO","NO","NO","NO",-4.999,"Deleterious",35.11,30.45,1080,155,1235,0.125506072874494,1074,151,1225,0.123265306122449,0.902783639622743,5,13,"Hotspot (-7)"]
["Hotspot, inspected","UPN_Tr2_051",17,74732959,"G","T","SRSF2","ENST00000392485","missense_variant","cCc/cAc|p.Pro95His/c.284C>A",6445,247,6710,0.0368107302533532,0,0,0,0,1,1,0,1,3,"NO","NO","COSM211504","haematopoietic_and_lymphoid_tissue",147,"NO","NO","NO","NO","NO","NO",-4.999,"Deleterious",34.41,31.03,3246,125,3382,0.0369603784742756,3199,122,3328,0.0366586538461538,0.948397669442714,5,13,"Hotspot (-2)"]
["Hotspot, Expert,, Cosmic, prediction","UPN_Tr2_062",17,74732959,"G","T","SRSF2","ENST00000392485","missense_variant","cCc/cAc|p.Pro95His/c.284C>A",467,593,1060,0.559433962264151,1,1,1,1,1,1,1,1,8,"NO","NO","COSM211504","haematopoietic_and_lymphoid_tissue",147,"NO","NO","NO","NO","NO","NO",-4.999,"Deleterious",33.41,29.91,231,302,533,0.566604127579737,236,291,527,0.552182163187856,0.66505142244665,5,13,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_102",17,74732959,"G","T","SRSF2","ENST00000392485","missense_variant","cCc/cAc|p.Pro95His/c.284C>A",2306,376,2684,0.140089418777943,1,1,0,1,1,1,0,1,6,"NO","NO","COSM211504","haematopoietic_and_lymphoid_tissue",147,"NO","NO","NO","NO","NO","NO",-4.999,"Deleterious",33.75,32,1158,190,1349,0.140845070422535,1148,186,1335,0.139325842696629,0.911571492356694,5,13,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_106",17,74732959,"G","T","SRSF2","ENST00000392485","missense_variant","cCc/cAc|p.Pro95His/c.284C>A",5498,942,6454,0.145955996281376,1,1,0,1,1,1,0,1,6,"NO","NO","COSM211504","haematopoietic_and_lymphoid_tissue",147,"NO","NO","NO","NO","NO","NO",-4.999,"Deleterious",33.68,31.77,2754,476,3237,0.147049737411183,2744,466,3217,0.144855455393224,0.805145949166862,5,13,"Hotspot (-7)"]
["Expert, inspected, freq","UPN_Tr2_016",20,31022286,"TACC","T","ASXL1","ENST00000375687","stop_gained+disruptive_inframe_deletion","taccag/tag|p.Tyr591_Gln592delinsTer/c.1773_1775delCCA",4104,3351,7466,0.448834717385481,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-8.203,"Deleterious",34.87,"NA",924,488,1414,0.345120226308345,3180,2863,6052,0.473066754791804,2,1,1,"Probably True (-7)"]
["Expert, inspected, freq","UPN_Tr2_043",20,31022288,"C","A","ASXL1","ENST00000375687","stop_gained","taC/taA|p.Tyr591*/c.1773C>A",11049,367,11453,0.032044005937309,0,0,0,0,1,1,0,1,3,"NO","NO","COSM1681609","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NA","NO","NO","NA","NA",35.2,34.31,1834,70,1915,0.0365535248041775,9215,297,9538,0.0311386034808136,0.225922671136928,1,1,"Hotspot (-3)"]
["Hotspot, Sanger other sample","UPN_Tr2_017",20,31022402,"TCACCACTGCCATAGAGAGGCGGC","T","ASXL1","ENST00000375687","frameshift_variant","agagaggcggccaccactgccatc/|p.Glu635fs/c.1900_1922delAGAGAGGCGGCCACCACTGCCAT",1578,209,1796,0.116369710467706,0,1,1,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO",0.0001403,"NO","NO","NA","NA",32.25,"NA",999,0,1002,0,579,209,794,0.263224181360202,2,5,5,"Hotspot (-7)"]
["Hotspot, Sanger other sample","UPN_Tr2_018",20,31022402,"TCACCACTGCCATAGAGAGGCGGC","T","ASXL1","ENST00000375687","frameshift_variant","agagaggcggccaccactgccatc/|p.Glu635fs/c.1900_1922delAGAGAGGCGGCCACCACTGCCAT",3207,40,3257,0.0122812404052809,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO",0.0001403,"NO","NO","NA","NA",32.76,"NA",1670,0,1672,0,1537,40,1585,0.0252365930599369,2,5,5,"Hotspot (-1)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_049",20,31022402,"TCACCACTGCCATAGAGAGGCGGC","T","ASXL1","ENST00000375687","frameshift_variant","ggtcaccactgccatagagaggcggcc/|p.Glu635fs/c.1887_1909delCACCACTGCCATAGAGAGGCGGC",2797,221,3034,0.0728411338167436,0,0,1,1,1,1,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO",0.0001403,"NO","NO","NA","NA",31.65,"NA",1674,0,1678,0,1123,221,1356,0.162979351032448,2,5,5,"Hotspot (-6)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_104",20,31022402,"TCACCACTGCCATAGAGAGGCGGC","T","ASXL1","ENST00000375687","frameshift_variant","agagaggcggccaccactgccatc/|p.Glu635fs/c.1900_1922delAGAGAGGCGGCCACCACTGCCAT",2779,300,3085,0.0972447325769854,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO",0.0001403,"NO","NO","NA","NA",32.46,"NA",1624,0,1627,0,1155,300,1458,0.205761316872428,2,5,5,"Hotspot (-6)"]
["Hotspot, Sanger other sample","UPN_Tr2_108",20,31022402,"TCACCACTGCCATAGAGAGGCGGC","T","ASXL1","ENST00000375687","frameshift_variant","agagaggcggccaccactgccatc/|p.Glu635fs/c.1900_1922delAGAGAGGCGGCCACCACTGCCAT",4019,202,4238,0.0476639924492685,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO",0.0001403,"NO","NO","NA","NA",32.69,"NA",2176,0,2182,0,1843,202,2056,0.0982490272373541,2,5,5,"Hotspot (-6)"]
["Hotspot, Sanger validated, 2nd Illumina, freq","UPN_Tr2_001",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",5021,1280,5082,0.251869342778434,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.97,"NA",4643,1208,4662,0.259116259116259,378,72,420,0.171428571428571,0.0176815584687023,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_025",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",12618,3737,12944,0.288705191594561,0,1,1,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.05,"NA",10054,3115,10100,0.308415841584158,2564,622,2844,0.218706047819972,4.78320537657465E-007,110,229,"Hotspot (-4)"]
["Hotspot, expert, freq","UPN_Tr2_031",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",7067,1331,7228,0.184144991698949,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.02,"NA",5410,1067,5437,0.196247930844216,1657,264,1791,0.147403685092127,0.00394554209108369,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_045",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",16513,3856,16813,0.22934633914233,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.77,"NA",14739,3499,14833,0.235892941414414,1774,357,1980,0.18030303030303,0.00656272910190714,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_036",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",8226,1714,8443,0.203008409333175,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.05,"NA",6363,1450,6402,0.226491721337082,1863,264,2041,0.129348358647722,7.60243534357355E-012,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_039",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",7957,1773,8195,0.216351433801098,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.84,"NA",5890,1448,5924,0.24442943956786,2067,325,2271,0.143108762659621,4.92504320719052E-012,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_060",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",3518,469,3543,0.132373694609088,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.91,"NA",3163,409,3172,0.128940731399748,355,60,371,0.161725067385445,0.0764942871481327,110,229,"Hotspot (-3)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_040",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",7712,1476,7927,0.186199066481645,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.95,"NA",5821,1189,5849,0.203282612412378,1891,287,2078,0.138113570741097,2.17178188215983E-005,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, 2nd Illumina, freq","UPN_Tr2_083",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",2987,732,3004,0.243675099866844,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.01,"NA",2686,662,2692,0.24591381872214,301,70,312,0.224358974358974,0.730870493450664,110,229,"Hotspot (-4)"]
["Hotspot, Sanger validated, freq","UPN_Tr2_098",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",6441,932,6481,0.143804968369079,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.14,"NA",5674,845,5694,0.148401826484018,767,87,787,0.110546378653113,0.0213903788474461,110,229,"Hotspot (-4)"]
["Expert, Cosmic, bq","UPN_Tr2_079",20,31022460,"G","T","ASXL1","ENST00000375687","stop_gained","Gga/Tga|p.Gly649*/c.1945G>T",2035,374,2418,0.154673283705542,0,1,0,0,1,0,0,0,2,"NO","NO","COSM142309","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",35.1,34.55,1748,374,2129,0.175669328323156,287,0,289,0,2,1,2,"Probably True (-1)"]
["Expert, freq","UPN_Tr2_101",20,31022547,"A","AG","ASXL1","ENST00000375687","frameshift_variant","gga/ggGa|p.Gly680fs/c.2036dupG",10077,2797,10167,0.275105734238222,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.74,"NA",4976,1331,5032,0.264507154213037,5101,1466,5135,0.285491723466407,0.0954508783784564,1,1,"Probably True (-5)"]
["Hotspot, Expert, Cosmic, bq","UPN_Tr2_062",20,31022592,"C","T","ASXL1","ENST00000375687","stop_gained","Cga/Tga|p.Arg693*/c.2077C>T",5253,1512,6772,0.223272297696397,1,1,0,0,1,1,0,0,4,0,"NO","COSM51388","central_nervous_system, haematopoietic_and_lymphoid_tissue","2, 17","NO","rs373221034","NO",5.765E-005,"NO","NO","NA","NA",35.39,34.25,3311,1,3312,0.000301932367149758,1942,1511,3460,0.436705202312139,2,4,4,"Hotspot (-3)"]
["Hotspot, Expert, Cosmic, bq","UPN_Tr2_070",20,31022592,"C","T","ASXL1","ENST00000375687","stop_gained","Cga/Tga|p.Arg693*/c.2077C>T",4372,376,4758,0.0790248003362757,0,0,0,0,1,1,0,0,2,0,"NO","COSM51388","central_nervous_system, haematopoietic_and_lymphoid_tissue","2, 17","NO","rs373221034","NO",5.765E-005,"NO","NO","NA","NA",35.32,34.55,3221,5,3235,0.00154559505409583,1151,371,1523,0.243598161523309,2,4,4,"Hotspot (-2)"]
["Expert, freq","UPN_Tr2_079",20,31022607,"CCG","C","ASXL1","ENST00000375687","frameshift_variant","ccgcct/|p.Pro699fs/c.2094_2095delGC",4215,766,4994,0.153384060873048,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.08,"NA",2384,442,2832,0.156073446327684,1831,324,2162,0.149861239592969,2,1,1,"Probably True (-6)"]
["454 validated, Expert, freq","UPN_Tr2_039",20,31022732,"CA","C","ASXL1","ENST00000375687","frameshift_variant","aca/|p.Thr740fs/c.2218delA",11653,3011,14754,0.204080249423885,1,1,0,1,1,1,0,0,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.05,"NA",8108,2,8149,0.000245428886979998,3545,3009,6605,0.4555639666919,2,1,1,"Probably True (-3)"]
["inspected","UPN_Tr2_082",20,31022757,"C","T","ASXL1","ENST00000375687","stop_gained","Caa/Taa|p.Gln748*/c.2242C>T",23420,4003,27517,0.145473707162845,1,0,0,1,1,1,0,1,5,"NO","NO","COSM307766","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO","NA","NA",34.68,35.21,17517,3074,20657,0.148811540882025,5903,929,6860,0.135422740524781,0.0067546692173954,1,1,"Probably True (-4)"]
["454 validated, Expert, bq, freq","UPN_Tr2_012",20,31022784,"C","T","ASXL1","ENST00000375687","stop_gained","Cag/Tag|p.Gln757*/c.2269C>T",8702,2020,10750,0.187906976744186,1,1,0,0,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO",2.471E-005,"NO","NO","NA","NA",35.12,35.2,5336,2003,7352,0.272442872687704,3366,17,3398,0.0050029429075927,2,1,1,"Probably True (-2)"]
["Sanger validated, 454 validated, freq","UPN_Tr2_035",20,31023336,"CCT","C","ASXL1","ENST00000375687","frameshift_variant","cct/|p.Pro941fs/c.2822_2823delCT",6567,2051,8633,0.237576740414688,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.02,"NA",3303,1034,4342,0.238139106402579,3264,1017,4291,0.237007690515031,0.939512581761124,2,2,"Probably True (-5)"]
["Sanger other sample, 454 validated, Expert, freq","UPN_Tr2_011",20,31023336,"CCT","C","ASXL1","ENST00000375687","frameshift_variant","cct/|p.Pro941fs/c.2822_2823delCT",11875,4492,16418,0.273602143988306,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.13,"NA",5975,2258,8260,0.273365617433414,5900,2234,8158,0.273841627849963,0.958094852961407,2,2,"Probably True (-5)"]
["inspected","UPN_Tr2_102",20,31023591,"G","T","ASXL1","ENST00000375687","stop_gained","Gga/Tga|p.Gly1026*/c.3076G>T",12168,1755,13951,0.125797433875708,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.77,33.86,6124,870,7011,0.124090714591356,6044,885,6940,0.127521613832853,0.557102990567421,1,1,"Probably True (-5)"]
["Hotspot, Expert, Cosmic, bq","UPN_Tr2_061",20,31023625,"G","A","ASXL1","ENST00000375687","stop_gained","tGg/tAg|p.Trp1037*/c.3110G>A",19464,4532,24094,0.188096621565535,0,1,0,1,1,1,0,1,5,"NO","NO","COSM2270981","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",33.63,34.5,9799,2283,12138,0.188086999505685,9665,2249,11956,0.188106390097022,0.973686823723508,1,1,"Probably True (-4)"]
["Expert, freq","UPN_Tr2_094",20,31024079,"T","TG","ASXL1","ENST00000375687","frameshift_variant","gcc/gGcc|p.Ala1189fs/c.3565dupG",18233,5214,18373,0.283785990311871,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.85,"NA",9062,2584,9145,0.282558775287042,9171,2630,9228,0.285002167316862,0.862848846292582,1,1,"Probably True (-5)"]
["Expert, bq, freq","UPN_Tr2_050",20,31024339,"C","A","ASXL1","ENST00000375687","stop_gained","tCa/tAa|p.Ser1275*/c.3824C>A",14575,5287,19919,0.265424971133089,0,1,1,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.03,33.69,13922,5065,19039,0.266032879878145,653,222,880,0.252272727272727,0.411445105351557,1,2,"Probably True (-5)"]
["454 validated, Expert, freq","UPN_Tr2_089",20,31024457,"T","TA","ASXL1","ENST00000375687","frameshift_variant","cag/Acag|p.Gln1315fs/c.3942_3943insA",15777,2209,15840,0.139457070707071,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.66,"NA",5592,62,5609,0.01105366375468,10185,2147,10231,0.20985240934415,2,1,1,"Probably True (-2)"]
["inspected","UPN_Tr2_034",21,36164764,"T","TG","RUNX1","ENST00000437180","frameshift_variant","gcc/gccC|p.Met371fs/c.1110dupC",3218,236,3231,0.0730424017332095,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.33,"NA",2402,234,2414,0.0969345484672742,816,2,817,0.00244798041615667,2,1,1,"Probably True (-1)"]
["Expert, freq","UPN_Tr2_094",21,36206881,"C","CT","RUNX1","ENST00000437180","frameshift_variant","cta/ctaA|p.Asp211fs/c.630dupA",9168,1980,9188,0.2154984762734,1,1,0,1,1,1,0,0,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.17,"NA",7023,1977,7037,0.2809435839136,2145,3,2151,0.00139470013947001,2,1,1,"Probably True (-3)"]
["Sanger validated, 454 validated, IonT_1 validated, Expert, bq, prediction","UPN_Tr2_036",21,36206893,"G","A","RUNX1","ENST00000437180","missense_variant","Cgg/Tgg|p.Arg207Trp/c.619C>T",14812,1559,16399,0.0950667723641686,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.351,"Deleterious",34.79,35.49,12456,1558,14039,0.110976565282428,2356,1,2360,0.000423728813559322,2,1,1,"Probably True (-1)"]
["Hotspot, Sanger other sample, 454 validated, Expert, dbSNP flag, Cosmic, bq, prediction","UPN_Tr2_005",21,36231782,"C","T","RUNX1","ENST00000437180","missense_variant","cGa/cAa|p.Arg201Gln/c.602G>A",1442,639,2083,0.306769083053289,1,1,1,1,1,0,1,1,7,"NO","NO","COSM24805","breast, haematopoietic_and_lymphoid_tissue, oesophagus","1, 13, 1","NO","rs74315450","YES","NO","NO","NO",-3.686,"Deleterious",35.58,34.92,1442,639,2083,0.306769083053289,0,0,0,"NA",1,1,1,"Hotspot (-9)"]
["inspected","UPN_Tr2_043",21,36231783,"G","A","RUNX1","ENST00000437180","stop_gained","Cga/Tga|p.Arg201*/c.601C>T",9644,414,10090,0.0410307234886026,0,0,0,0,1,0,0,1,2,"NO","NO","COSM24771","haematopoietic_and_lymphoid_tissue",10,"NO","NO","NO","NO","NO","NO","NA","NA",35.08,34.91,9644,414,10090,0.0410307234886026,0,0,0,"NA",1,2,2,"Hotspot (-3)"]
["inspected","UPN_Tr2_098",21,36231783,"G","A","RUNX1","ENST00000437180","stop_gained","Cga/Tga|p.Arg201*/c.601C>T",7174,422,7613,0.0554314987521345,0,0,0,1,1,0,0,1,3,"NO","NO","COSM24771","haematopoietic_and_lymphoid_tissue",10,"NO","NO","NO","NO","NO","NO","NA","NA",35.36,35.55,7174,422,7613,0.0554314987521345,0,0,0,"NA",1,2,2,"Hotspot (-5)"]
["inspected","UPN_Tr2_102",21,36231803,"T","A","RUNX1","ENST00000437180","missense_variant","aAa/aTa|p.Lys194Ile/c.581A>T",5964,1131,7115,0.158959943780745,1,1,0,1,1,0,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.365,"Deleterious",35.35,35.12,5964,1131,7115,0.158959943780745,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["Expert, freq, no SNP database","UPN_Tr2_016",21,36231855,"T","TGG","RUNX1","ENST00000437180","frameshift_variant","acc/accCC|p.Ile177fs/c.527_528dupCC",11954,5002,12030,0.415793848711554,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.63,"NA",6045,2551,6085,0.419227608874281,5909,2451,5945,0.412279226240538,0.613413232534097,1,1,"Probably True (-5)"]
["Hotspot, 2nd Illumina, 454 validated, Expert, Cosmic, bq, effect","UPN_Tr2_006",21,36252866,"G","A","RUNX1","ENST00000437180","stop_gained","Cga/Tga|p.Arg166*/c.496C>T",1613,768,2382,0.322418136020151,1,1,1,1,1,0,1,1,7,"NO","NO","COSM24769","haematopoietic_and_lymphoid_tissue",10,"NO","NO","NO","NO","NO","NO","NA","NA",35.27,34.27,1613,768,2382,0.322418136020151,0,0,0,"NA",1,1,2,"Hotspot (-8)"]
["Hotspot","UPN_Tr2_085",21,36252866,"G","C","RUNX1","ENST00000437180","missense_variant","Cga/Gga|p.Arg166Gly/c.496C>G",18069,2665,20797,0.128143482233014,0,1,0,1,1,0,0,1,4,"NO","NO","COSM24742","haematopoietic_and_lymphoid_tissue",5,"NO","NO","NO","NO","NO","NO",-6.288,"Deleterious",35.01,35.05,18069,2665,20797,0.128143482233014,0,0,0,"NA",1,1,2,"Hotspot (-7)"]
["Expert, freq","UPN_Tr2_081",21,36252884,"C","CA","RUNX1","ENST00000437180","frameshift_variant","aat/aatT|p.Asp160fs/c.477dupT",2040,630,2043,0.308370044052863,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.1,"NA",2040,630,2043,0.308370044052863,0,0,0,"NA",1,1,1,"Probably True (-5)"]
["2nd Illumina, 454 validated, Expert, bq, prediction, freq","UPN_Tr2_013",21,36259178,"G","T","RUNX1","ENST00000437180","missense_variant","Cac/Aac|p.His105Asn/c.313C>A",1390,647,2040,0.317156862745098,1,1,1,1,1,0,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.94,"Deleterious",35.36,34.81,1390,647,2040,0.317156862745098,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["Expert, bq, prediction, freq","UPN_Tr2_110",21,36259186,"A","G","RUNX1","ENST00000437180","missense_variant","cTg/cCg|p.Leu102Pro/c.305T>C",4419,2013,6438,0.312674743709226,1,1,0,1,1,0,1,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.971,"Deleterious",34.45,35.4,4419,2013,6438,0.312674743709226,0,0,0,"NA",1,4,4,"Probably True (-4)"]
["Expert, prediction, freq","UPN_Tr2_068",21,44514772,"C","CATACTG","U2AF1","ENST00000291552","inframe_insertion","tat/tatCAGTAT|p.Tyr158_Glu159insGlnTyr/c.469_474dupCAGTAT",13928,4923,13974,0.352297123228854,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.623,"Deleterious",35.46,"NA",13920,4923,13966,0.352498925963053,8,0,8,0,0.121524250513898,1,1,"Probably True (-6)"]
["Hotspot","UPN_Tr2_055",21,44514777,"T","C","U2AF1","ENST00000291552","missense_variant","cAg/cGg|p.Gln157Arg/c.470A>G",5595,596,6210,0.0959742351046699,0,1,0,1,1,0,0,1,4,0.0116,"NO","COSM1724986, COSM211532","haematopoietic_and_lymphoid_tissue",26,"NO","rs371246226","NO","NA","NO","NO",-3.835,"Deleterious",35.03,34.59,5595,596,6210,0.0959742351046699,0,0,0,"NA",1,2,6,"Hotspot (-7)"]
["Hotspot","UPN_Tr2_057",21,44514777,"T","C","U2AF1","ENST00000291552","missense_variant","cAg/cGg|p.Gln157Arg/c.470A>G",7373,406,7817,0.0519380836638096,0,0,0,0,1,0,0,1,2,0.0116,"NO","COSM1724986, COSM211532","haematopoietic_and_lymphoid_tissue",26,"NO","rs371246226","NO","NA","NO","NO",-3.835,"Deleterious",35.12,34.19,7373,406,7817,0.0519380836638096,0,0,0,"NA",1,2,6,"Hotspot (-4)"]
["Hotspot, 2nd Illumina, IonT_2 validated, Expert, Cosmic, prediction, bq","UPN_Tr2_001",21,44514777,"T","G","U2AF1","ENST00000291552","missense_variant","cAg/cCg|p.Gln157Pro/c.470A>C",1926,928,2870,0.323344947735192,1,1,1,1,1,1,1,1,8,"NO","NO","COSM211534, COSM1318797","haematopoietic_and_lymphoid_tissue",62,"NO","NO","NO","NA","NO","NO",-5.687,"Deleterious",35.19,34.81,1926,923,2865,0.32216404886562,0,5,5,1,0.00360832013751721,4,6,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_017",21,44514777,"T","G","U2AF1","ENST00000291552","missense_variant","cAg/cCg|p.Gln157Pro/c.470A>C",1403,1120,2534,0.441988950276243,1,1,1,1,1,0,1,1,7,"NO","NO","COSM211534, COSM1318797","haematopoietic_and_lymphoid_tissue",62,"NO","NO","NO","NA","NO","NO",-5.687,"Deleterious",35.36,35.19,1403,1120,2534,0.441988950276243,0,0,0,"NA",1,4,6,"Hotspot (-7)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_060",21,44514777,"T","G","U2AF1","ENST00000291552","missense_variant","cAg/cCg|p.Gln157Pro/c.470A>C",7370,1039,8463,0.122769703414865,0,1,0,1,1,0,0,1,4,"NO","NO","COSM211534, COSM1318797","haematopoietic_and_lymphoid_tissue",62,"NO","NO","NO","NA","NO","NO",-5.687,"Deleterious",35.22,34.75,7370,1039,8463,0.122769703414865,0,0,0,"NA",1,4,6,"Hotspot (-5)"]
["Hotspot, Expert, Cosmic, prediction, bq","UPN_Tr2_073",21,44514777,"T","G","U2AF1","ENST00000291552","missense_variant","cAg/cCg|p.Gln157Pro/c.470A>C",3337,880,4236,0.207743153918791,1,1,1,1,1,0,0,1,6,"NO","NO","COSM211534, COSM1318797","haematopoietic_and_lymphoid_tissue",62,"NO","NO","NO","NA","NO","NO",-5.687,"Deleterious",35.22,34.97,3337,880,4236,0.207743153918791,0,0,0,"NA",1,4,6,"Hotspot (-7)"]
["Hotspot","UPN_Tr2_057",21,44524456,"G","A","U2AF1","ENST00000291552","missense_variant","tCt/tTt|p.Ser34Phe/c.101C>T",23424,1387,24930,0.0556357801845166,0,0,0,0,1,1,0,1,3,0,"NO","COSM1142948, COSM166866","cervix, endometrium, haematopoietic_and_lymphoid_tissue, liver, lung, pancreas, stomach, urinary_tract","4, 6, 71, 8, 26, 20, 2, 6","NO","rs371769427","NO","NA","NO","NO",-5.862,"Deleterious",31.57,33.45,11785,683,12504,0.0546225207933461,11639,704,12426,0.0566553999678094,0.455591171102739,3,3,"Hotspot (-4)"]
["Hotspot","UPN_Tr2_076",21,44524456,"G","A","U2AF1","ENST00000291552","missense_variant","tCt/tTt|p.Ser34Phe/c.101C>T",23248,1810,25167,0.0719195772241427,0,0,0,0,1,1,0,1,3,0,"NO","COSM1142948, COSM166866","cervix, endometrium, haematopoietic_and_lymphoid_tissue, liver, lung, pancreas, stomach, urinary_tract","4, 6, 71, 8, 26, 20, 2, 6","NO","rs371769427","NO","NA","NO","NO",-5.862,"Deleterious",31.37,32.53,11629,883,12560,0.0703025477707006,11619,927,12607,0.0735305782501785,0.317089414810881,3,3,"Hotspot (-4)"]
["Hotspot","UPN_Tr2_087",21,44524456,"G","A","U2AF1","ENST00000291552","missense_variant","tCt/tTt|p.Ser34Phe/c.101C>T",31578,1242,32993,0.0376443488012609,0,0,0,0,1,1,0,1,3,0,"NO","COSM1142948, COSM166866","cervix, endometrium, haematopoietic_and_lymphoid_tissue, liver, lung, pancreas, stomach, urinary_tract","4, 6, 71, 8, 26, 20, 2, 6","NO","rs371769427","NO","NA","NO","NO",-5.862,"Deleterious",31.33,32.81,15819,613,16510,0.0371290127195639,15759,629,16483,0.0381605290299096,0.622911777124237,3,3,"Hotspot (-4)"]
["Expert, bq, freq","UPN_Tr2_034","X",15822253,"G","A","ZRSR2","ENST00000307771","stop_gained","tGg/tAg|p.Trp111*/c.332G>A",411,181,593,0.305227655986509,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.42,35.86,411,181,593,0.305227655986509,0,0,0,"NA",1,2,2,"Probably True (-5)"]
["2nd Illumina, 454 validated, Expert, bq, no SNP database","UPN_Tr2_006","X",15826386,"G","A","ZRSR2","ENST00000307771","missense_variant","Gaa/Aaa|p.Glu144Lys/c.430G>A",1924,1788,3722,0.4803868888,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO",1,"NO","NO",-1.535,"Tolerated",35.47,33.52,1924,1788,3722,0.4803868888,0,0,0,"NA",1,1,1,"Probably True (-6)"]
["2nd Illumina, Expert, prediction, bq","UPN_Tr2_083","X",15838407,"G","A","ZRSR2","ENST00000307771","missense_variant","tGc/tAc|p.Cys302Tyr/c.905G>A",4831,6464,11350,0.569515418502203,1,1,0,1,1,1,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.763,"Deleterious",33.32,33.62,2435,3281,5732,0.572400558269365,2396,3183,5618,0.566571733713065,0.717828054410209,1,1,"Probably True (-6)"]
["Sanger validated, 2nd Illumina, 454 validated, IonT_1 validated, Expert, prediction, bq","UPN_Tr2_004","X",15840894,"C","G","ZRSR2","ENST00000307771","missense_variant","tgC/tgG|p.Cys326Trp/c.978C>G",44,387,432,0.895833333333333,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.461,"Deleterious",34.93,35.06,44,387,432,0.895833333333333,0,0,0,"NA",1,1,1,"Probably True (-6)"]
[{"$nulls":14},{"$f":"SUM(O2:O220)","v":154},{"$f":"SUM(P2:P220)","v":182},{"$f":"SUM(Q2:Q220)","v":77},{"$f":"SUM(R2:R220)","v":174},{"$f":"SUM(S2:S220)","v":215},{"$f":"SUM(T2:T220)","v":124},{"$f":"SUM(U2:U220)","v":67},{"$f":"SUM(V2:V220)","v":196}]

{"sheet":"TP Polymorphisms","index":2,"n_rows":403,"n_cols":50,"rows_kept":403,"cut":false,"hidden":false,"merged":[]}
["True because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["Inspected, ESP6500, ExAC, freq","UPN_Tr2_030",11,119149352,"A","G","CBL","ENST00000264033","missense_variant","Aat/Gat|p.Asn454Asp/c.1360A>G",3962,3983,7985,0.4988102693,1,1,1,1,1,0,1,1,7,0.0116,"NO","COSM34082","haematopoietic_and_lymphoid_tissue",1,"NO","rs371850672","NO",8.236E-006,"NO","NO",-0.376,"Tolerated",34.38,35,0,0,0,"NA",3962,3983,7985,0.4988102693,1,1,1,"Polymorphism"]
["2nd Illumina, ESP6500, ExAC, freq","UPN_Tr2_083",12,12006412,"G","A","ETV6","ENST00000396373","missense_variant","cGg/cAg|p.Arg127Gln/c.380G>A",6808,6615,13442,0.4921142687,1,1,0,1,1,0,1,1,6,0.093,"NO","NO","NO","O","NO","rs140357643","NO",0.0005271,"NO","NO",-0.621,"Tolerated",32.97,34.83,6808,6615,13442,0.4921142687,0,0,0,"NA",1,1,1,"Polymorphism"]
["ESP6500, 1000G, freq","UPN_Tr2_008",12,12022496,"T","C","ETV6","ENST00000396373","missense_variant","cTc/cCc|p.Leu201Pro/c.602T>C",5071,4218,9408,0.4483418367,1,1,1,1,1,0,1,1,7,0.6628,0.0119,"NO","NO","O","NO","rs145477191","NO","NA","NO","YES",-1.19,"Tolerated",32.71,34.38,0,0,0,"NA",5071,4218,9408,0.4483418367,1,1,1,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_001",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",5,1837,1846,0.9951245937,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",30.8,34.36,0,0,0,"NA",5,1837,1846,0.9951245937,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_014",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",17,3358,3379,0.9937851435,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.76,34.39,0,0,0,"NA",17,3358,3379,0.9937851435,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_015",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",31,5232,5286,0.989784336,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25.94,34.41,0,0,0,"NA",31,5232,5286,0.989784336,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_016",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1227,1410,2644,0.5332829047,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.96,34.13,0,0,0,"NA",1227,1410,2644,0.5332829047,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_017",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",595,742,1341,0.5533184191,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.39,34.33,0,0,0,"NA",595,742,1341,0.5533184191,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_018",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1236,1460,2702,0.5403404885,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.25,34.51,0,0,0,"NA",1236,1460,2702,0.5403404885,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_019",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",18,2937,2959,0.9925650558,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",27,34.34,0,0,0,"NA",18,2937,2959,0.9925650558,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_020",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",14,2015,2036,0.9896856582,1,1,1,1,1,0,1,0,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.14,34.26,0,0,0,"NA",14,2015,2036,0.9896856582,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_021",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,2970,2993,0.9923154026,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.95,34.44,0,0,0,"NA",21,2970,2993,0.9923154026,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_002",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",715,991,1714,0.5781796966,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.06,34.34,0,0,0,"NA",715,991,1714,0.5781796966,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_003",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1,407,408,0.9975490196,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,34.28,0,0,0,"NA",1,407,408,0.9975490196,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_022",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",20,3637,3668,0.9915485278,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",20.75,34.4,0,0,0,"NA",20,3637,3668,0.9915485278,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_023",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,3469,3498,0.9917095483,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",24.48,34.27,0,0,0,"NA",21,3469,3498,0.9917095483,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_041",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",2572,3919,6514,0.6016272644,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.74,33.68,0,0,0,"NA",2572,3919,6514,0.6016272644,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_024",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",12,1556,1568,0.9923469388,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25.75,34.2,0,0,0,"NA",12,1556,1568,0.9923469388,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_025",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,5123,5155,0.9937924345,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.24,34.35,0,0,0,"NA",21,5123,5155,0.9937924345,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_026",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",15,4324,4352,0.9935661765,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.8,34.39,0,0,0,"NA",15,4324,4352,0.9935661765,1,106,106,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_004",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",83,125,209,0.5980861244,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.02,34.41,0,0,0,"NA",83,125,209,0.5980861244,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_027",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,4547,4578,0.9932284841,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",24.29,34.23,0,0,0,"NA",21,4547,4578,0.9932284841,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_089",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1144,1524,2673,0.5701459035,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.62,33.99,0,0,0,"NA",1144,1524,2673,0.5701459035,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_042",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",63,6316,6407,0.9857967848,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",27.02,33.48,0,0,0,"NA",63,6316,6407,0.9857967848,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_028",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",17,3708,3736,0.9925053533,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.06,34.4,0,0,0,"NA",17,3708,3736,0.9925053533,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_043",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",28,3731,3774,0.9886062533,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.86,33.58,0,0,0,"NA",28,3731,3774,0.9886062533,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_029",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",16,3638,3667,0.992091628,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",27.75,34.16,0,0,0,"NA",16,3638,3667,0.992091628,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_030",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1768,2068,3842,0.5382613222,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.23,34.33,0,0,0,"NA",1768,2068,3842,0.5382613222,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_031",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1221,1460,2690,0.5427509294,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.23,34.39,0,0,0,"NA",1221,1460,2690,0.5427509294,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_005",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",7,675,683,0.9882869693,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",26,34.12,0,0,0,"NA",7,675,683,0.9882869693,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_032",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",13,1296,1309,0.9900687548,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25.77,34.11,0,0,0,"NA",13,1296,1309,0.9900687548,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_046",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",45,6896,6972,0.9890992542,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",19.87,33.68,0,0,0,"NA",45,6896,6972,0.9890992542,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_033",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1269,1469,2744,0.5353498542,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.08,34.24,0,0,0,"NA",1269,1469,2744,0.5353498542,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_034",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",435,596,1033,0.5769603098,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35,34.19,0,0,0,"NA",435,596,1033,0.5769603098,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_047",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",49,7119,7204,0.9882009994,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25.04,33.43,0,0,0,"NA",49,7119,7204,0.9882009994,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_048",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",49,6651,6731,0.9881146932,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",26.61,33.59,0,0,0,"NA",49,6651,6731,0.9881146932,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_035",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",43,6686,6741,0.9918409731,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.02,34.27,0,0,0,"NA",43,6686,6741,0.9918409731,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_036",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",5751,6631,12412,0.534241057,1,1,0,1,1,0,0,1,5,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.12,34.27,0,0,0,"NA",5751,6631,12412,0.534241057,1,106,106,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_006",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",7,1888,1897,0.9952556668,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",24.43,33.96,0,0,0,"NA",7,1888,1897,0.9952556668,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_050",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1619,2455,4088,0.6005381605,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.64,33.63,0,0,0,"NA",1619,2455,4088,0.6005381605,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_037",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",30,6010,6048,0.9937169312,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",26.47,34.5,0,0,0,"NA",30,6010,6048,0.9937169312,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_051",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",2390,3145,5557,0.5659528523,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.69,33.44,0,0,0,"NA",2390,3145,5557,0.5659528523,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_052",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",19,3085,3115,0.9903691814,1,1,1,1,1,0,1,0,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.42,33.68,0,0,0,"NA",19,3085,3115,0.9903691814,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_038",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",48,6732,6799,0.9901456096,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.35,34.41,0,0,0,"NA",48,6732,6799,0.9901456096,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_039",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",6987,5618,12631,0.444778719,1,1,0,1,1,0,0,1,5,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.2,34.37,0,0,0,"NA",6987,5618,12631,0.444778719,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_053",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",2635,3402,6063,0.5611083622,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.55,33.45,0,0,0,"NA",2635,3402,6063,0.5611083622,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_054",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",36,4166,4228,0.9853358562,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",24.83,33.69,0,0,0,"NA",36,4166,4228,0.9853358562,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_007",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",22,4776,4806,0.9937578027,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.41,33.89,0,0,0,"NA",22,4776,4806,0.9937578027,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_008",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",26,6836,6880,0.9936046512,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.73,34.01,0,0,0,"NA",26,6836,6880,0.9936046512,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_009",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,5510,5550,0.9927927928,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",24.48,34.26,0,0,0,"NA",21,5510,5550,0.9927927928,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_010",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",15,3895,3915,0.9948914432,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",17.4,34.13,0,0,0,"NA",15,3895,3915,0.9948914432,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_011",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",16,3641,3667,0.9929097355,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.25,34.27,0,0,0,"NA",16,3641,3667,0.9929097355,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_055",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",34,6196,6253,0.9908843755,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.21,33.62,0,0,0,"NA",34,6196,6253,0.9908843755,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_056",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",186,3776,3970,0.9511335013,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",33.21,33.56,0,0,0,"NA",186,3776,3970,0.9511335013,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_090",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",10,1637,1651,0.9915202907,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",15.8,33.8,0,0,0,"NA",10,1637,1651,0.9915202907,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_057",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1296,2174,3478,0.6250718804,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.69,33.4,0,0,0,"NA",1296,2174,3478,0.6250718804,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_058",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",61,7067,7157,0.9874248987,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.31,33.5,0,0,0,"NA",61,7067,7157,0.9874248987,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_059",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",5,432,438,0.9863013699,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,33.56,0,0,0,"NA",5,432,438,0.9863013699,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_012",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",4,2382,2392,0.995819398,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",30.5,34.2,0,0,0,"NA",4,2382,2392,0.995819398,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_060",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",342,520,862,0.6032482599,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.64,33.74,0,0,0,"NA",342,520,862,0.6032482599,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_040",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",3114,2516,5646,0.4456252214,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",35.15,34.4,0,0,0,"NA",3114,2516,5646,0.4456252214,1,106,106,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_013",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",4,1241,1258,0.9864864865,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25,33.91,0,0,0,"NA",4,1241,1258,0.9864864865,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_091",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",14,2551,2573,0.9914496696,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",20.79,33.89,0,0,0,"NA",14,2551,2573,0.9914496696,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_092",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",7,1545,1558,0.9916559692,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",19.71,33.75,0,0,0,"NA",7,1545,1558,0.9916559692,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_093",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",12,2197,2216,0.9914259928,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.33,33.97,0,0,0,"NA",12,2197,2216,0.9914259928,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_061",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",7,1071,1079,0.9925857275,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",17.14,33.39,0,0,0,"NA",7,1071,1079,0.9925857275,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_062",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",8,2084,2099,0.9928537399,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",16.75,33.44,0,0,0,"NA",8,2084,2099,0.9928537399,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_064",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",440,444,891,0.4983164983,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.32,33.59,0,0,0,"NA",440,444,891,0.4983164983,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_065",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",0,183,184,0.9945652174,1,1,1,0,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",0,33.6,0,0,0,"NA",0,183,184,0.9945652174,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_067",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1,120,121,0.9917355372,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,32.77,0,0,0,"NA",1,120,121,0.9917355372,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_068",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",187,195,385,0.5064935065,0,1,1,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.05,33.74,2,0,2,0,185,195,383,0.5091383812,0.2389825617,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_069",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",209,390,602,0.6478405316,0,1,1,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.01,33.53,0,0,0,"NA",209,390,602,0.6478405316,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_070",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",8,470,480,0.9791666667,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25,33.7,0,0,0,"NA",8,470,480,0.9791666667,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_071",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1123,1280,2417,0.5295821266,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.27,33.2,0,0,0,"NA",1123,1280,2417,0.5295821266,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_072",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",974,1504,2481,0.6062071745,1,1,1,1,1,1,1,1,8,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",33.94,33.31,0,1,1,1,974,1503,2480,0.6060483871,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_073",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",3,675,678,0.9955752212,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,33.07,0,0,0,"NA",3,675,678,0.9955752212,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_074",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",62,108,170,0.6352941176,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.45,33.65,0,0,0,"NA",62,108,170,0.6352941176,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_075",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",4,1775,1787,0.9932848349,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",29.5,33.17,0,0,0,"NA",4,1775,1787,0.9932848349,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_076",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",353,551,906,0.6081677704,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.54,32.98,0,0,0,"NA",353,551,906,0.6081677704,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_077",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",3,441,444,0.9932432432,1,1,1,1,1,0,1,1,7,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,33.46,0,0,0,"NA",3,441,444,0.9932432432,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_078",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",8,1260,1276,0.987460815,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",19.5,33.59,0,0,0,"NA",8,1260,1276,0.987460815,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_079",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",3,697,704,0.9900568182,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23.67,33.22,0,0,0,"NA",3,697,704,0.9900568182,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_080",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",21,1618,1643,0.9847839318,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",26.19,33.49,0,0,0,"NA",21,1618,1643,0.9847839318,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_081",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",27,3390,3425,0.9897810219,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",18.26,33.14,0,0,0,"NA",27,3390,3425,0.9897810219,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_082",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",186,312,499,0.625250501,0,1,0,1,1,0,1,1,5,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.44,33.22,0,0,0,"NA",186,312,499,0.625250501,1,106,106,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_083",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",489,487,978,0.4979550102,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.17,34.15,0,0,0,"NA",489,487,978,0.4979550102,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_084",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",6,907,913,0.9934282585,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",21.33,33.34,0,0,0,"NA",6,907,913,0.9934282585,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_085",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",169,174,345,0.5043478261,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.67,32.78,0,0,0,"NA",169,174,345,0.5043478261,1,106,106,"Polymorphism"]
["2nd Illumina, ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_086",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",2,196,198,0.9898989899,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",14,33.71,0,0,0,"NA",2,196,198,0.9898989899,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_087",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",201,321,523,0.6137667304,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.78,33.2,0,0,0,"NA",201,321,523,0.6137667304,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_088",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",231,179,411,0.4355231144,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.3,33.48,0,0,0,"NA",231,179,411,0.4355231144,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_094",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",867,1349,2222,0.6071107111,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.7,33.77,0,0,0,"NA",867,1349,2222,0.6071107111,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_095",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",27,3146,3179,0.9896193772,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",29,33.87,0,0,0,"NA",27,3146,3179,0.9896193772,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_096",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",19,2363,2391,0.9882894187,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.84,33.92,0,0,0,"NA",19,2363,2391,0.9882894187,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_097",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",204,2448,2657,0.921339857,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.43,33.68,0,0,0,"NA",204,2448,2657,0.921339857,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_098",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",13,2510,2529,0.9924871491,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",23,33.61,0,0,0,"NA",13,2510,2529,0.9924871491,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_099",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",4,1385,1393,0.9942569993,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",28.25,33.77,0,0,0,"NA",4,1385,1393,0.9942569993,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_100",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1235,1468,2708,0.5420974889,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.74,33.93,0,0,0,"NA",1235,1468,2708,0.5420974889,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_101",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1026,1338,2370,0.564556962,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.74,33.94,0,0,0,"NA",1026,1338,2370,0.564556962,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_102",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",14,2554,2575,0.9918446602,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.07,33.67,0,0,0,"NA",14,2554,2575,0.9918446602,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_103",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",20,3026,3051,0.9918059653,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",20.4,33.9,0,0,0,"NA",20,3026,3051,0.9918059653,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_104",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",8,2716,2729,0.9952363503,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.25,33.83,0,0,0,"NA",8,2716,2729,0.9952363503,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_105",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",59,2066,2129,0.9704086426,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",33.08,33.77,0,0,0,"NA",59,2066,2129,0.9704086426,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_106",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1280,1580,2867,0.5510987095,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.78,33.63,0,0,0,"NA",1280,1580,2867,0.5510987095,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_107",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1457,1854,3318,0.5587703436,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.65,33.88,0,0,0,"NA",1457,1854,3318,0.5587703436,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_108",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",24,4411,4442,0.9930211616,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",25,33.83,0,0,0,"NA",24,4411,4442,0.9930211616,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_109",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",20,3774,3799,0.9934193209,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",22.6,33.91,0,0,0,"NA",20,3774,3799,0.9934193209,1,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_110",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1336,1576,2920,0.5397260274,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.49,33.89,1,0,1,0,1335,1576,2919,0.5399109284,0.4587912088,106,106,"Polymorphism"]
["ESP6500, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_111",17,7579472,"G","C","TP53","ENST00000269305","missense_variant","cCc/cGc|p.Pro72Arg/c.215C>G",1307,1669,2981,0.5598792352,1,1,0,1,1,0,1,1,6,25.4767,0.7147,"COSM3766190, COSM3766191, COSM250061, COSM3766193, COSM3766192","large_intestine, liver, pancreas, pleura, prostate, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract, central_nervous_system","10, 5, 15, 5, 5, 100, 5, 7, 5, 1","rs1042522","rs1042522","NO",0.659,"NO","YES",0.155,"Tolerated",34.76,33.89,0,0,0,"NA",1307,1669,2981,0.5598792352,1,106,106,"Polymorphism"]
["freq, neutrtal effect","UPN_Tr2_103",17,7579575,"G","C","TP53","ENST00000269305","missense_variant","Caa/Gaa|p.Gln38Glu/c.112C>G",3541,3458,7029,0.4919618722,1,1,0,1,1,0,1,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.115,"Tolerated",33.71,34.36,3541,3458,7029,0.4919618722,0,0,0,"NA",1,3,3,"Polymorphism"]
["freq, inframe, 2 samples","UPN_Tr2_015",19,33792731,"G","GGCGGGT","CEBPA","ENST00000498907","inframe_insertion","ccg/cACCCGCcg|p.His195_Pro196dup/c.584_589dupACCCGC",410,168,410,0.4097560976,1,1,1,1,1,1,0,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.291,"Tolerated",33.24,"NA",209,95,209,0.4545454545,201,73,201,0.3631840796,0.2340766831,2,2,"Polymorphism"]
["freq, inframe, 2 samples","UPN_Tr2_040",19,33792731,"G","GGCGGGT","CEBPA","ENST00000498907","inframe_insertion","ccg/cACCCGCcg|p.His195_Pro196dup/c.584_589dupACCCGC",121,78,121,0.6446280992,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.291,"Tolerated",32.26,"NA",64,44,64,0.6875,57,34,57,0.5964912281,0.6636402699,2,2,"Polymorphism"]
["ESP6500, 1000G, ExAC, freq","UPN_Tr2_023",2,25523096,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu30Ala/c.89A>C",2915,2652,5580,0.4752688172,1,1,1,1,1,1,1,1,8,0.2093,0.007,"COSM307361","haematopoietic_and_lymphoid_tissue",1,"NO","rs143730975","NO",0.002916,"NO","YES",-0.129,"Tolerated",33.28,33.23,1468,1340,2816,0.4758522727,1447,1312,2764,0.4746743849,0.9145202508,1,1,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_001",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",34,8420,8476,0.99339311,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.71,34.47,34,8402,8458,0.9933790494,0,18,18,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_014",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",31,13591,13643,0.9961885216,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.87,34.65,31,13587,13639,0.9961874038,0,4,4,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_015",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",53,17984,18062,0.9956815414,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.49,34.75,53,17960,18038,0.9956757955,0,24,24,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_016",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",16,9117,9148,0.9966112812,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.12,34.66,16,9106,9137,0.9966072015,0,11,11,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_017",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",13,6125,6145,0.9967453214,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.76,13,6122,6142,0.9967437317,0,3,3,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_018",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",20,9151,9182,0.9966238292,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.6,34.72,20,9146,9177,0.9966219898,0,5,5,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_019",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",20,10062,10094,0.9968297999,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.72,20,10055,10087,0.9968275999,0,7,7,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_020",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,8869,8897,0.9968528718,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.73,18,8864,8892,0.9968511021,0,5,5,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_021",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",24,10394,10440,0.9955938697,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.08,34.75,24,10388,10434,0.995591336,0,6,6,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_002",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",34,10925,10989,0.9941759942,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.35,34.57,34,10925,10989,0.9941759942,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_003",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",4,2096,2106,0.9952516619,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.44,4,2095,2105,0.9952494062,0,1,1,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_022",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",30,13618,13662,0.9967793881,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.13,34.63,30,13613,13657,0.996778209,0,5,5,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_023",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",23,14957,14998,0.9972663022,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.65,34.58,23,14949,14990,0.9972648432,0,8,8,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_041",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",0,480,481,0.9979209979,1,1,0,0,1,0,1,1,5,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",0,34.39,0,480,481,0.9979209979,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_024",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",16,6813,6836,0.9966354593,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.76,16,6813,6836,0.9966354593,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_025",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",33,16256,16309,0.9967502606,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.09,34.64,33,16243,16296,0.9967476681,0,13,13,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_026",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",36,15980,16041,0.9961972446,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.25,34.7,36,15969,16029,0.9962567846,0,11,12,0.9166666667,1,111,111,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_004",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",3,1856,1865,0.9951742627,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.51,3,1856,1865,0.9951742627,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_027",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,17106,17139,0.9980745668,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.56,34.71,18,17095,17128,0.9980733302,0,11,11,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_089",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",20,10678,10724,0.9957105558,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.8,34.67,20,10668,10714,0.9957065522,0,10,10,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_042",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",47,17232,17323,0.9947468683,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.94,34.32,47,17232,17323,0.9947468683,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_028",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",23,12137,12179,0.996551441,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.91,34.7,23,12126,12168,0.9965483235,0,11,11,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_043",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",44,14969,15044,0.9950146238,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.11,34.36,44,14948,15023,0.9950076549,0,21,21,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_044",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",7,3808,3817,0.9976421273,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.34,7,3808,3817,0.9976421273,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_029",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",25,14660,14699,0.9973467583,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.8,34.66,25,14660,14699,0.9973467583,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_030",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",22,14516,14561,0.9969095529,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.41,34.72,22,14510,14555,0.9969082789,0,6,6,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_031",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",23,9615,9652,0.9961665976,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.83,34.66,23,9609,9646,0.9961642131,0,6,6,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_005",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",7,3643,3662,0.9948115784,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.43,34.54,7,3642,3661,0.9948101612,0,1,1,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_045",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",80,20981,21114,0.993700862,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.69,34.34,80,20965,21098,0.9936960849,0,16,16,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_032",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",8,5174,5187,0.9974937343,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.25,34.62,8,5174,5187,0.9974937343,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_046",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",60,19708,19812,0.9947506562,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.4,34.37,60,19706,19810,0.9947501262,0,2,2,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_033",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",21,11257,11287,0.997342075,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.1,34.69,21,11250,11280,0.9973404255,0,7,7,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_034",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",9,4352,4368,0.9963369963,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.11,34.75,9,4350,4366,0.9963353184,0,2,2,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_047",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",102,20562,20716,0.9925661325,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.07,34.31,102,20562,20716,0.9925661325,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_048",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",33,2479,2518,0.9845115171,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.52,34.42,33,2469,2508,0.9844497608,0,10,10,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_035",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",37,12136,12183,0.9961421653,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.62,34.62,37,12135,12182,0.9961418486,0,1,1,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_036",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",37,12159,12212,0.9956600066,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.05,34.63,37,12156,12209,0.9956589401,0,3,3,1,1,111,111,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_006",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",8,3752,3765,0.9965471448,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",30.5,34.47,8,3752,3765,0.9965471448,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_049",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",38,9416,9478,0.9934585356,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.97,34.26,38,9415,9477,0.9934578453,0,1,1,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_050",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",71,19446,19572,0.9935622318,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.13,34.28,71,19446,19572,0.9935622318,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_037",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",43,22519,22589,0.9969011466,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.12,34.73,43,22493,22563,0.9968975757,0,26,26,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_051",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",75,15144,15257,0.9925935636,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.77,34.28,75,15139,15252,0.9925911356,0,5,5,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_052",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",54,17195,17286,0.9947356242,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.54,34.33,54,17193,17284,0.994735015,0,2,2,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_038",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",57,24747,24832,0.9965769974,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.86,34.69,57,24740,24825,0.9965760322,0,7,7,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_039",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",25,11125,11167,0.9962389182,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.08,34.7,25,11125,11167,0.9962389182,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_053",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",66,22307,22427,0.9946493066,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.24,34.35,66,22305,22425,0.9946488294,0,2,2,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_054",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",38,14161,14230,0.9951510892,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.45,34.33,38,14161,14230,0.9951510892,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_007",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",47,24088,24206,0.9951251756,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.6,34.4,47,24088,24206,0.9951251756,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_008",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",66,33299,33451,0.9954560402,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.39,34.48,66,33253,33405,0.995449783,0,46,46,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_009",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",83,28400,28565,0.9942237003,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.89,34.4,83,28373,28538,0.9942182353,0,27,27,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_010",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",53,18583,18683,0.9946475405,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.92,34.41,53,18580,18680,0.9946466809,0,3,3,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_011",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",46,21595,21702,0.9950695788,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.83,34.41,46,21573,21680,0.9950645756,0,22,22,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_055",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",40,22219,22307,0.99605505,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.38,34.34,40,22218,22306,0.9960548731,0,1,1,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_056",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",3,2222,2231,0.9959659346,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.46,3,2222,2231,0.9959659346,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_090",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",21,9753,9797,0.9955088292,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.67,34.66,21,9687,9730,0.9955806783,0,66,67,0.9850746269,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_057",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",39,18671,18761,0.9952028143,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.44,34.25,39,18671,18761,0.9952028143,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_058",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",32,16833,16922,0.9947405744,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.78,34.32,32,16833,16922,0.9947405744,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_059",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",27,7073,7122,0.9931199101,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.74,33.61,27,7073,7122,0.9931199101,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_012",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",23,11819,11869,0.9957873452,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.26,34.44,23,11819,11869,0.9957873452,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_060",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",31,10830,10901,0.9934868361,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.16,33.56,31,10830,10901,0.9934868361,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_040",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",15,9153,9183,0.9967330938,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.47,34.66,15,9153,9183,0.9967330938,0,0,0,"NA",1,111,111,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_013",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",13,7112,7154,0.9941291585,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.62,34.42,13,7098,7140,0.9941176471,0,14,14,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_091",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",10,6610,6629,0.997133806,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",31.6,34.65,10,6610,6629,0.997133806,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_092",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",22,5923,5957,0.9942924291,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.82,34.64,22,5923,5957,0.9942924291,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_093",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",7,6491,6511,0.9969282752,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.86,34.58,7,6491,6511,0.9969282752,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_061",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",19,10969,11019,0.9954623832,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.47,33.77,19,10969,11019,0.9954623832,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_062",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",12,10442,10480,0.9963740458,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35,33.67,12,10419,10457,0.9963660706,0,23,23,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_063",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,10035,10083,0.995239512,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.56,33.6,18,10035,10083,0.995239512,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_064",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",13,5555,5580,0.9955197133,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.15,33.66,13,5555,5580,0.9955197133,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_065",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",10,6689,6722,0.9950907468,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.6,33.6,10,6687,6720,0.9950892857,0,2,2,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_066",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",20,9771,9810,0.9960244648,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.7,33.57,20,9771,9810,0.9960244648,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_067",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",11,9068,9110,0.9953896817,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,33.52,11,9068,9110,0.9953896817,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_068",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",13,7908,7945,0.995342983,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.69,33.65,13,7908,7945,0.995342983,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_069",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,10849,10884,0.9967842705,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.56,33.68,18,10849,10884,0.9967842705,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_070",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",20,6813,6852,0.9943082312,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.8,33.74,20,6783,6822,0.9942832014,0,30,30,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_071",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",17,8355,8395,0.9952352591,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.41,33.73,17,8355,8395,0.9952352591,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_072",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",16,8109,8141,0.996069279,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.75,33.64,16,8109,8141,0.996069279,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_073",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",9,5758,5782,0.9958491871,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.56,33.63,9,5758,5782,0.9958491871,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_074",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",14,5579,5608,0.994828816,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.71,33.6,14,5579,5608,0.994828816,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_075",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",24,11867,11929,0.9948025819,1,1,1,1,1,0,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.17,33.59,24,11867,11929,0.9948025819,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_076",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,10072,10116,0.9956504547,1,1,1,1,1,1,1,1,8,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.5,33.72,18,10063,10107,0.9956465816,0,9,9,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_077",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",27,10630,10682,0.9951319978,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.89,33.65,27,10630,10682,0.9951319978,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_078",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",21,10669,10720,0.9952425373,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.76,33.75,21,10669,10720,0.9952425373,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_079",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",16,6968,7004,0.99486008,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.19,33.74,16,6968,7004,0.99486008,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_080",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",11,10452,10505,0.9949547834,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.64,33.65,11,10452,10505,0.9949547834,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_081",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",52,8666,8745,0.9909662664,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.21,33.52,52,8666,8745,0.9909662664,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_082",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",30,10403,10468,0.9937905999,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.3,33.58,30,10403,10468,0.9937905999,0,0,0,"NA",1,111,111,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_083",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",18,11776,11826,0.9957720277,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.78,33.77,18,11776,11826,0.9957720277,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_084",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",29,10909,10970,0.9944393801,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.52,33.75,29,10909,10970,0.9944393801,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_085",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",11,8225,8263,0.995401186,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.27,33.68,11,8225,8263,0.995401186,0,0,0,"NA",1,111,111,"Polymorphism"]
["2nd Illumina, 1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_086",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",7,5685,5714,0.9949247462,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",32.86,33.64,7,5685,5714,0.9949247462,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_087",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",28,11106,11164,0.9948047295,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",30.96,33.59,28,11106,11164,0.9948047295,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_088",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",19,8143,8182,0.9952334393,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.63,33.49,19,8143,8182,0.9952334393,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_094",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",23,12440,12497,0.9954389053,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.91,34.7,23,12437,12494,0.9954378101,0,3,3,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_095",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",15,10411,10448,0.9964586524,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.68,15,10392,10429,0.9964522006,0,19,19,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_096",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",17,11391,11419,0.9975479464,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.71,34.78,17,11387,11415,0.9975470872,0,4,4,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_097",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",31,12833,12900,0.9948062016,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.03,34.65,31,12830,12897,0.9948049934,0,3,3,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_098",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",14,9426,9458,0.9966166209,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.71,34.69,14,9410,9442,0.9966108875,0,16,16,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_099",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",12,5803,5835,0.9945158526,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",31.58,34.66,12,5799,5831,0.9945120906,0,4,4,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_100",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",21,9139,9180,0.9955337691,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",36,34.64,21,9128,9169,0.9955284109,0,11,11,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_101",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",32,9584,9633,0.9949133188,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.06,34.75,32,9575,9624,0.9949085619,0,9,9,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_102",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",29,9975,10038,0.9937238494,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.86,34.7,29,9958,10020,0.9938123752,0,17,18,0.9444444444,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_103",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",17,9526,9556,0.9968606111,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.24,34.69,17,9522,9552,0.9968592965,0,4,4,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_104",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",22,12235,12286,0.9958489337,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",33.82,34.65,22,12229,12280,0.9958469055,0,6,6,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_105",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",17,10972,11026,0.995102485,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.47,34.77,17,10969,11023,0.9951011521,0,3,3,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_106",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",31,12444,12515,0.9943268078,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.03,34.67,31,12444,12515,0.9943268078,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_107",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",35,17050,17139,0.9948071649,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35,34.62,35,17033,17122,0.9948020091,0,17,17,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_108",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",38,14355,14437,0.9943201496,1,1,0,1,1,0,1,1,6,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.05,34.68,38,14355,14437,0.9943201496,0,0,0,"NA",1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_109",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",36,13932,13996,0.9954272649,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.25,34.71,36,13916,13980,0.9954220315,0,16,16,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_110",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",37,16015,16093,0.9951531722,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",35.3,34.71,37,16006,16084,0.9951504601,0,9,9,1,1,111,111,"Polymorphism"]
["1000G, dbSNP, ExAC, freq, many samples","UPN_Tr2_111",20,31022959,"T","C","ASXL1","ENST00000375687","missense_variant","cTg/cCg|p.Leu815Pro/c.2444T>C",19,12195,12245,0.9959167007,1,1,0,1,1,1,1,1,7,0,1,"NO","NO","O","rs6058694","rs6058694","NO",1,"NO","NO",1.033,"Tolerated",34.37,34.74,19,12193,12243,0.9959160337,0,2,2,1,1,111,111,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect","UPN_Tr2_038",20,31023821,"G","T","ASXL1","ENST00000375687","missense_variant","gaG/gaT|p.Glu1102Asp/c.3306G>T",32517,11915,44673,0.2667159134,1,1,0,0,1,1,0,1,5,1,0.0209,"COSM36205","haematopoietic_and_lymphoid_tissue, soft_tissue","13, 1","NO","rs139115934","NO",0.01,"NO","YES",-1.374,"Tolerated",35.69,34.88,20353,6,20521,0.0002923834,12164,11909,24152,0.4930854588,2,2,2,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect","UPN_Tr2_084",20,31023821,"G","T","ASXL1","ENST00000375687","missense_variant","gaG/gaT|p.Glu1102Asp/c.3306G>T",26947,7163,34296,0.2088581759,1,1,0,0,1,1,0,0,4,1,0.0209,"COSM36205","haematopoietic_and_lymphoid_tissue, soft_tissue","13, 1","NO","rs139115934","NO",0.01,"NO","YES",-1.374,"Tolerated",35.46,33.43,20265,7,20404,0.00034307,6682,7156,13892,0.5151166139,2,2,2,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect, freq","UPN_Tr2_090",21,36259324,"A","G","RUNX1","ENST00000437180","missense_variant","tTg/tCg|p.Leu56Ser/c.167T>C",3292,2261,5570,0.4059245961,1,1,0,0,1,1,1,1,6,1.4623,0.0169,"COSM24756","haematopoietic_and_lymphoid_tissue",7,"NO","rs111527738","NO",0.015,"NO","YES",-1.109,"Tolerated",35.53,35.42,473,1,485,0.0020618557,2819,2260,5085,0.4444444444,2,6,6,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect, freq","UPN_Tr2_075",21,36259324,"A","G","RUNX1","ENST00000437180","missense_variant","tTg/tCg|p.Leu56Ser/c.167T>C",578,402,984,0.4085365854,1,1,0,0,1,0,1,1,5,1.4623,0.0169,"COSM24756","haematopoietic_and_lymphoid_tissue",7,"NO","rs111527738","NO",0.015,"NO","YES",-1.109,"Tolerated",34.96,34.83,137,0,140,0,441,402,844,0.4763033175,2,6,6,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect, freq","UPN_Tr2_080",21,36259324,"A","G","RUNX1","ENST00000437180","missense_variant","tTg/tCg|p.Leu56Ser/c.167T>C",619,491,1112,0.4415467626,1,1,0,0,1,1,1,1,6,1.4623,0.0169,"COSM24756","haematopoietic_and_lymphoid_tissue",7,"NO","rs111527738","NO",0.015,"NO","YES",-1.109,"Tolerated",34.92,34.88,180,2,182,0.010989011,439,489,930,0.5258064516,2,6,6,"Polymorphism"]
["ESP6500, 1000G, ExAC, neutral effect, freq","UPN_Tr2_106",21,36259324,"A","G","RUNX1","ENST00000437180","missense_variant","tTg/tCg|p.Leu56Ser/c.167T>C",4392,4641,9042,0.5132714001,1,1,0,0,1,1,0,1,5,1.4623,0.0169,"COSM24756","haematopoietic_and_lymphoid_tissue",7,"NO","rs111527738","NO",0.015,"NO","YES",-1.109,"Tolerated",35.62,35.5,753,4,758,0.0052770449,3639,4637,8284,0.5597537422,2,6,6,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_002",4,106155185,"C","G","TET2","ENST00000380013","missense_variant","cCt/cGt|p.Pro29Arg/c.86C>G",6634,6654,13355,0.4982403594,1,1,1,1,1,1,1,1,8,1.5465,"NO","COSM5020248, COSM5020249","soft_tissue",4,"rs12498609","rs12498609","NO",0.06,"NO","YES",-1.923,"Tolerated",34.99,34.42,3300,3312,6645,0.4984198646,3334,3342,6710,0.4980625931,0.9723225099,1,1,"Polymorphism"]
["ESP6500, ExAC, freq","UPN_Tr2_034",4,106155199,"C","T","TET2","ENST00000380013","missense_variant","Ctc/Ttc|p.Leu34Phe/c.100C>T",2738,2807,5572,0.5037688442,1,1,1,1,1,1,1,1,8,1.8953,"NO","NO","NO","O","NO","rs111948941","NO",0.015,"NO","YES",-1.31,"Tolerated",35.05,33.74,1363,1393,2775,0.501981982,1375,1414,2797,0.5055416518,0.9144536301,2,2,"Polymorphism"]
["ESP6500, ExAC, freq","UPN_Tr2_006",4,106155199,"C","T","TET2","ENST00000380013","missense_variant","Ctc/Ttc|p.Leu34Phe/c.100C>T",3999,4113,8141,0.5052204889,1,1,1,1,1,1,1,1,8,1.8953,"NO","NO","NO","O","NO","rs111948941","NO",0.015,"NO","YES",-1.31,"Tolerated",35,33.83,2018,2070,4112,0.5034046693,1981,2043,4029,0.5070737156,0.9115894683,2,2,"Polymorphism"]
["ESP6500, dbSNP, neutral effect, freq","UPN_Tr2_034",4,106155751,"G","A","TET2","ENST00000380013","missense_variant","Gtg/Atg|p.Val218Met/c.652G>A",2102,2310,4420,0.5226244344,0,1,1,1,1,0,1,1,6,2.093,"NO","COSM4416139, COSM4416140","haematopoietic_and_lymphoid_tissue",2,"rs6843141","rs6843141","NO","NA","NO","YES",0.498,"Tolerated",35.17,35.35,2102,2310,4420,0.5226244344,0,0,0,"NA",1,2,2,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, neutral effect, freq","UPN_Tr2_006",4,106155751,"G","A","TET2","ENST00000380013","missense_variant","Gtg/Atg|p.Val218Met/c.652G>A",4558,4781,9380,0.5097014925,1,1,1,1,1,0,1,1,7,2.093,"NO","COSM4416139, COSM4416140","haematopoietic_and_lymphoid_tissue",2,"rs6843141","rs6843141","NO","NA","NO","YES",0.498,"Tolerated",34.92,35.2,4558,4781,9380,0.5097014925,0,0,0,"NA",1,2,2,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_017",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",3362,3054,6424,0.4754047323,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",35.19,35.24,188,120,310,0.3870967742,3174,2934,6114,0.4798822375,0.001916889,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_023",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",40,15826,15895,0.9956590123,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.83,35.24,2,713,718,0.9930362117,38,15113,15177,0.9957830928,0.7014694846,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_045",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",8307,8795,17136,0.5132469655,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.8,35.23,371,388,767,0.5058670143,7936,8407,16369,0.5135927668,0.8819010696,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_040",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",94,30776,30937,0.9947958755,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.19,35.24,12,1484,1506,0.9853917663,82,29292,29431,0.9952770888,0.0019420372,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_062",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",7183,7338,14556,0.5041220115,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.38,35.19,303,240,546,0.4395604396,6880,7098,14010,0.5066381156,0.0029045329,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_074",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",6540,7104,13668,0.5197541703,1,1,1,1,1,1,1,1,8,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.4,35.07,238,317,561,0.5650623886,6302,6787,13107,0.5178149081,0.0151490938,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_079",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",5132,5470,10630,0.5145813735,1,1,0,1,1,1,1,1,7,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",34.34,35.09,167,249,418,0.5956937799,4965,5221,10212,0.5112612613,0.0006503462,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_104",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",6606,6879,13500,0.5095555556,1,1,0,1,1,1,1,1,7,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",35.19,35.35,214,293,512,0.572265625,6392,6586,12988,0.5070834617,0.0020500378,10,10,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq","UPN_Tr2_108",4,106156163,"G","A","TET2","ENST00000380013","missense_variant","gGt/gAt|p.Gly355Asp/c.1064G>A",7459,7626,15095,0.5052003975,1,1,0,1,1,1,1,1,7,4.3721,"NO","NO","NO","O","rs61744960","rs61744960","NO",0.027,"NO","YES",-1.044,"Tolerated",35.17,35.46,246,238,487,0.4887063655,7213,7388,14608,0.5057502738,0.5482787454,10,10,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_015",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",18664,8341,27042,0.3084461208,1,1,1,0,1,1,1,1,7,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.56,35.81,10213,27,10254,0.0026331188,8451,8314,16788,0.4952346914,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_020",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",9387,4219,13617,0.3098332966,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.55,35.85,5024,18,5049,0.0035650624,4363,4201,8568,0.4903127918,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_021",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",10198,4433,14638,0.3028419183,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.51,35.83,5613,16,5630,0.0028419183,4585,4417,9008,0.4903419183,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_089",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",9845,8228,18096,0.4546861185,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.52,35.87,6806,15,6832,0.0021955504,3039,8213,11264,0.7291370739,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_030",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",8704,12441,21169,0.5876989938,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.59,35.85,7689,16,7716,0.0020736133,1015,12425,13453,0.9235858173,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_037",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",17710,9915,27657,0.3584987526,1,1,1,0,1,1,1,1,7,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.57,35.83,9792,33,9840,0.0033536585,7918,9882,17817,0.5546388281,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_038",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",26116,11584,37725,0.307064281,1,1,1,0,1,1,1,1,7,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.54,35.85,14461,11,14481,0.000759616,11655,11573,23244,0.4978919291,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_066",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",26318,13867,40249,0.3445302989,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.2,35.68,13624,20,13679,0.0014620952,12694,13847,26570,0.5211516748,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_073",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",10200,2871,13093,0.2192774765,1,1,0,0,1,1,1,0,5,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.26,35.67,6959,4,6976,0.0005733945,3241,2867,6117,0.4686938042,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_075",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",20264,9243,29556,0.31272838,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.18,35.7,10737,10,10778,0.0009278159,9527,9233,18778,0.491692406,2,13,13,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_100",4,106156187,"C","T","TET2","ENST00000380013","missense_variant","cCt/cTt|p.Pro363Leu/c.1088C>T",6154,9859,16024,0.6152646031,1,1,0,0,1,1,1,1,6,5.8953,"NO","COSM5020142, COSM5020141","soft_tissue",4,"rs17253672","rs17253672","NO",0.048,"NO","YES",-1.15,"Tolerated",35.66,35.87,6128,23,6155,0.0037367994,26,9836,9869,0.9966561962,2,13,13,"Polymorphism"]
["2 samples, neutral effect, freq","UPN_Tr2_025",4,106157191,"G","A","TET2","ENST00000380013","missense_variant","Gtg/Atg|p.Val698Met/c.2092G>A",6211,6136,12363,0.4963196635,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.188,"Tolerated",35.29,35.55,6211,6136,12363,0.4963196635,0,0,0,"NA",1,2,2,"Polymorphism"]
["2 samples, neutral effect, freq","UPN_Tr2_096",4,106157191,"G","A","TET2","ENST00000380013","missense_variant","Gtg/Atg|p.Val698Met/c.2092G>A",2599,2581,5188,0.4974942174,1,1,0,1,1,0,1,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.188,"Tolerated",35.39,35.73,2599,2581,5188,0.4974942174,0,0,0,"NA",1,2,2,"Polymorphism"]
["ExAC, freq","UPN_Tr2_084",4,106157389,"C","A","TET2","ENST00000380013","missense_variant","Caa/Aaa|p.Gln764Lys/c.2290C>A",29998,32633,62795,0.5196751334,1,1,0,1,1,1,1,1,7,"NO","NO","NO","NA","NA","NO","NO","NO",1.647E-005,"NO","NO",-0.548,"Tolerated",33.62,34.28,14942,16253,31253,0.5200460756,15056,16380,31542,0.5193075899,0.9936180473,1,1,"Probably True (-6)"]
["2nd Illumina, ESP6500, ExAC, Sanger other sample","UPN_Tr2_004",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",3119,2767,5898,0.4691420821,1,1,1,1,1,1,1,1,8,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",31.23,35.04,1546,1371,2926,0.468557758,1573,1396,2972,0.469717362,1,6,6,"Polymorphism"]
["ESP6500, ExAC, Sanger other sample","UPN_Tr2_046",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",16574,16149,32811,0.4921824998,1,1,1,1,1,1,1,1,8,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",29.49,34.6,8188,8006,16261,0.4923436443,8386,8143,16550,0.4920241692,0.7568614693,6,6,"Polymorphism"]
["ESP6500, ExAC, Sanger other sample","UPN_Tr2_036",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",22810,16360,39254,0.416772813,1,1,1,1,1,1,1,1,8,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",30.18,34.95,11296,8133,19494,0.4172052939,11514,8227,19760,0.4163461538,0.7122538757,6,6,"Polymorphism"]
["ESP6500, ExAC, Sanger other sample","UPN_Tr2_090",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",10096,7799,17914,0.4353578207,1,1,0,1,1,1,1,1,7,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",31.37,34.99,5025,3883,8919,0.4353627088,5071,3916,8995,0.4353529739,0.9879723331,6,6,"Polymorphism"]
["ESP6500, ExAC, Sanger other sample","UPN_Tr2_063",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",12342,12778,25188,0.5073050659,1,1,1,1,1,1,1,1,8,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",31.1,34.38,6110,6344,12499,0.5075606048,6232,6434,12689,0.5070533533,0.8301107812,6,6,"Polymorphism"]
["ESP6500, ExAC, Sanger other sample","UPN_Tr2_065",4,106157698,"T","C","TET2","ENST00000380013","missense_variant","Tat/Cat|p.Tyr867His/c.2599T>C",14416,14055,28537,0.4925184848,1,1,1,1,1,1,1,1,8,1.2442,"NO","COSM327337","haematopoietic_and_lymphoid_tissue",1,"NO","rs144386291","NO",0.006894,"NO","YES",-1.224,"Tolerated",31.21,34.3,7141,6978,14168,0.4925183512,7275,7077,14369,0.4925186165,0.8495783148,6,6,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_051",4,106158350,"A","C","TET2","ENST00000380013","missense_variant","cAa/cCa|p.Gln1084Pro/c.3251A>C",5433,5368,10844,0.4950202877,1,1,1,1,1,0,1,1,7,0.3953,"NO","NO","NA","NA","NO","rs75056899","NO","NO","NO","YES",-1.959,"Tolerated",35.29,35.11,5423,5368,10834,0.4954772014,10,0,10,0,0.0019481731,2,2,"Polymorphism"]
["ESP6500, dbSNP, freq","UPN_Tr2_010",4,106158350,"A","C","TET2","ENST00000380013","missense_variant","cAa/cCa|p.Gln1084Pro/c.3251A>C",7443,6956,14453,0.4812841625,1,1,1,1,1,0,1,1,7,0.3953,"NO","NO","NA","NA","NO","rs75056899","NO","NO","NO","YES",-1.959,"Tolerated",35.33,35.33,7443,6956,14453,0.4812841625,0,0,0,"NA",1,2,2,"Polymorphism"]
["ESP6500, dbSNP, ExAC. Neutral effect, freq","UPN_Tr2_015",4,106196770,"G","A","TET2","ENST00000380013","missense_variant","atG/atA|p.Met1701Ile/c.5103G>A",15070,13309,28457,0.4676880908,1,1,1,1,1,1,1,1,8,0.7857,"NO","NO","NO","O","rs62623390","rs62623390","NO",0.003439,"NO","NO",-0.73,"Tolerated",34.76,34.74,7602,6728,14348,0.4689155283,7468,6581,14109,0.4664398611,0.8583872825,2,2,"Polymorphism"]
["ESP6500, dbSNP, ExAC. Neutral effect, freq","UPN_Tr2_054",4,106196770,"G","A","TET2","ENST00000380013","missense_variant","atG/atA|p.Met1701Ile/c.5103G>A",20280,3245,23614,0.1374184806,0,1,0,1,1,1,0,1,5,0.7857,"NO","NO","NO","O","rs62623390","rs62623390","NO",0.003439,"NO","NO",-0.73,"Tolerated",34.04,34.22,10231,1651,11911,0.1386113676,10049,1594,11703,0.136204392,0.6500386762,2,2,"Probably True (-2)"]
["ESP6500, ExAC. Neutral effect, freq","UPN_Tr2_078",4,106196819,"G","T","TET2","ENST00000380013","missense_variant","Gta/Tta|p.Val1718Leu/c.5152G>T",17106,14038,31289,0.4486560772,1,1,0,1,1,1,1,1,7,0.66,"NO","COSM41742","haematopoietic_and_lymphoid_tissue",11,"NO","rs142312318","NO",0.002662,"NO","NO",-0.339,"Tolerated",34.9,35.07,8059,4964,13079,0.3795397202,9047,9074,18210,0.4982976387,2,7,7,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_015",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",14520,16389,31031,0.5281492701,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.49,35.34,7894,8949,16902,0.5294639688,6626,7440,14129,0.5265765447,0.680380262,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_020",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",7184,7110,14359,0.4951598301,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.51,35.41,3975,3978,7993,0.4976854748,3209,3132,6366,0.4919886899,0.4588698851,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_021",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",7457,8222,15748,0.5220980442,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.48,35.43,4146,4697,8889,0.5284058949,3311,3525,6859,0.5139233124,0.0550165416,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_089",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",5547,14436,20026,0.7208628783,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.54,35.26,2867,7779,10671,0.7289850998,2680,6657,9355,0.7115980759,0.0053318372,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_030",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",1786,21296,23116,0.9212666551,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.46,35.38,1045,11854,12918,0.9176343087,741,9442,10198,0.9258678172,0.0210294252,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_005",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",12,5394,5414,0.9963058737,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",30.5,35.27,4,3001,3011,0.9966788442,8,2393,2403,0.9958385352,0.1494430717,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_045",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",19272,19244,38744,0.4966962626,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.11,34.75,9630,9831,19603,0.5015048717,9642,9413,19141,0.4917715898,0.0284456163,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_047",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",21253,22890,44351,0.5161101215,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.11,34.82,10248,9996,20353,0.4911315285,11005,12894,23998,0.5372947746,9.7705344662835E-022,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_048",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",9778,9582,19429,0.4931802975,1,1,1,0,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.06,34.74,1177,1421,2609,0.5446531238,8601,8161,16820,0.485196195,1.22094230139232E-008,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_037",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",13718,15895,29708,0.5350410664,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.53,35.4,7245,8382,15681,0.5345322365,6473,7513,14027,0.5356098952,0.8978420729,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_038",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",20503,19890,40558,0.4904087973,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.5,35.39,11105,11275,22489,0.5013562186,9398,8615,18069,0.4767834413,3.47138550349038E-007,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_010",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",16645,15213,31976,0.4757630723,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.35,35.16,9444,8538,18059,0.4727836536,7201,6675,13917,0.4796292304,0.2725745847,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_055",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",19789,19738,39733,0.4967659125,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.1,34.81,10003,10227,20367,0.5021358079,9786,9511,19366,0.491118455,0.0118849434,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_066",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",29938,28356,58490,0.4848008207,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.09,34.68,6021,7108,13168,0.5397934386,23917,21248,45322,0.4688230881,1.79295608328713E-046,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_067",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",30481,29601,60295,0.4909362302,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.09,34.72,7069,7792,14937,0.5216576287,23412,21809,45358,0.4808192601,6.04696212772279E-019,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_068",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",20216,18923,39296,0.481550285,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.16,34.71,6369,6519,12959,0.5030480747,13847,12404,26337,0.4709723962,6.06938738676663E-010,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_073",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",12342,11488,23930,0.4800668617,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.16,34.74,4629,4465,9153,0.4878182017,7713,7023,14777,0.4752656155,0.0316855407,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_075",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",17780,18272,36184,0.5049745744,1,1,1,1,1,1,1,1,8,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.18,34.72,7242,7741,15051,0.5143179855,10538,10531,21133,0.4983201628,0.0016767587,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_082",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",26431,25246,51893,0.4865010695,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.12,34.63,7135,7654,14863,0.5149700599,19296,17592,37030,0.4750742641,7.12546509661189E-017,25,25,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_083",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",19567,19241,38968,0.4937641141,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.16,34.72,7048,7758,14881,0.5213359317,12519,11483,24087,0.4767301864,2.85252259694742E-018,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_085",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",29325,24677,54212,0.4551944219,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.11,34.67,5468,5780,11300,0.5115044248,23857,18897,42912,0.4403663311,4.34763676749689E-042,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_100",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",30,18277,18334,0.9968910221,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",17.23,35.19,12,9449,9478,0.9969402828,18,8828,8856,0.9968383017,0.2070253332,25,25,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_105",4,106196829,"T","G","TET2","ENST00000380013","missense_variant","tTg/tGg|p.Leu1721Trp/c.5162T>G",11492,8855,20389,0.4343028103,1,1,0,1,1,1,1,1,7,13.4821,"NO","COSM5020013","soft_tissue",4,"rs34402524","rs34402524","NO",0.118,"NO","YES",-0.294,"Tolerated",35.54,35.23,5690,4529,10243,0.4421556185,5802,4326,10146,0.4263749261,0.0211750334,25,25,"Polymorphism"]
["Sanger other sample; ESP6500, ExAC, freq, 2nd Illumina","UPN_Tr2_004",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",1488,1545,3037,0.5087257162,1,1,1,1,1,1,1,1,8,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",35.08,35.25,442,611,1054,0.5796963947,1046,934,1983,0.47100353,1.28004659429884E-008,6,6,"Polymorphism"]
["Sanger other sample;  ESP6500, ExAC, freq,","UPN_Tr2_046",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",14692,14460,29241,0.4945111316,1,1,1,1,1,1,1,1,8,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",34.86,35.01,7838,7337,15239,0.4814620382,6854,7123,14002,0.508713041,8.38193751514362E-006,6,6,"Polymorphism"]
["Sanger validated SNP,  ESP6500, ExAC, freq,","UPN_Tr2_036",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",24871,19073,44020,0.4332803271,1,1,1,1,1,1,1,1,8,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",35.38,35.4,13690,10213,23957,0.426305464,11181,8860,20063,0.4416089319,0.001803218,6,6,"Polymorphism"]
["Sanger other sample;  ESP6500, ExAC, freq,","UPN_Tr2_090",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",9672,6973,16670,0.4182963407,1,1,0,1,1,1,1,1,7,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",35.21,35.53,4733,3245,7995,0.4058786742,4939,3728,8675,0.429740634,0.0022858798,6,6,"Polymorphism"]
["Sanger other sample;  ESP6500, ExAC, freq,","UPN_Tr2_063",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",14241,14296,28600,0.4998601399,1,1,1,1,1,1,1,1,8,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",34.77,35.08,5609,5832,11464,0.5087229588,8632,8464,17136,0.4939309057,0.0157002529,6,6,"Polymorphism"]
["Sanger other sample;  ESP6500, ExAC, freq,","UPN_Tr2_065",4,106196834,"C","T","TET2","ENST00000380013","missense_variant","Cct/Tct|p.Pro1723Ser/c.5167C>T",16913,17135,34134,0.5019921486,1,1,1,1,1,1,1,1,8,1.2256,"NO","COSM1235472","haematopoietic_and_lymphoid_tissue, skin","1, 1","NO","rs146348065","NO",0.005322,"NO","YES",-1.591,"Tolerated",34.71,34.98,4356,4247,8618,0.4928057554,12557,12888,25516,0.5050948425,0.0396140342,6,6,"Polymorphism"]
["2nd Illumina,  ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_001",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",6316,7727,14062,0.5494950932,0,1,1,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.82,35.45,6265,12,6286,0.0019090041,51,7715,7776,0.9921553498,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_014",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",14584,6303,20909,0.3014491367,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.76,35.52,8518,36,8563,0.0042041341,6066,6267,12346,0.507613802,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_015",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",22672,8087,30817,0.2624200928,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.71,35.54,13579,50,13660,0.0036603221,9093,8037,17157,0.4684385382,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_016",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",10218,4078,14326,0.2846572665,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.78,35.54,5924,34,5971,0.0056941886,4294,4044,8355,0.484021544,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_017",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",7300,3189,10508,0.3034830605,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.7,35.56,4292,17,4318,0.0039370079,3008,3172,6190,0.5124394184,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_018",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",6265,8111,14405,0.563068379,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.89,35.59,6236,26,6282,0.0041388093,29,8085,8123,0.9953219254,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_019",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",12027,4709,16766,0.2808660384,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.73,35.55,7203,35,7250,0.0048275862,4824,4674,9516,0.4911727617,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_020",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",9721,4077,13814,0.2951353699,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.79,35.53,5702,21,5729,0.0036655612,4019,4056,8085,0.5016697588,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_003",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",2574,1064,3640,0.2923076923,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.73,35.46,1543,5,1549,0.003227889,1031,1059,2091,0.506456241,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_022",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8231,12242,20521,0.5965596219,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.88,35.57,8191,29,8246,0.0035168567,40,12213,12275,0.9949490835,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_023",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",9521,14103,23662,0.5960189333,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.9,35.55,9487,31,9548,0.0032467532,34,14072,14114,0.9970242313,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_041",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",229,69,298,0.2315436242,1,1,0,0,1,1,0,0,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.72,35.51,109,1,110,0.0090909091,120,68,188,0.3617021277,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_024",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8431,3330,11773,0.2828505903,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.73,35.56,5022,18,5046,0.0035671819,3409,3312,6727,0.4923442842,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_025",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",10674,14234,24945,0.5706153538,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.89,35.57,10645,43,10710,0.0040149393,29,14191,14235,0.996909027,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_026",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11328,15632,26998,0.5790058523,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.85,35.55,11295,47,11362,0.0041365957,33,15585,15636,0.9967382962,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_027",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11864,16554,28455,0.5817606747,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.88,35.59,11844,46,11916,0.0038603558,20,16508,16539,0.9981256424,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_042",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",16699,9428,26169,0.3602736062,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.64,35.19,8210,45,8268,0.0054426705,8489,9383,17901,0.5241606614,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_028",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8702,11569,20304,0.5697892041,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.87,35.58,8668,46,8737,0.0052649651,34,11523,11567,0.996196075,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_043",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",15215,6871,22125,0.3105536723,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.69,35.21,8460,38,8518,0.0044611411,6755,6833,13607,0.5021680018,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_044",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",2426,3931,6367,0.6174022302,1,1,1,0,1,1,1,1,7,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.77,35.25,2415,3,2421,0.0012391574,11,3928,3946,0.9954384187,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_029",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",17049,7056,24153,0.2921376227,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.76,35.56,10089,44,10157,0.0043319878,6960,7012,13996,0.5010002858,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_045",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",22603,9910,32580,0.3041743401,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.65,35.27,12617,57,12699,0.0044885424,9986,9853,19881,0.4955988129,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_046",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",17995,8028,26061,0.3080465063,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.67,35.24,10506,48,10572,0.0045402951,7489,7980,15489,0.5152043386,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_034",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",5054,2127,7196,0.2955808783,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.72,35.52,3040,5,3052,0.00163827,2014,2122,4144,0.5120656371,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_035",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",27856,13738,41665,0.329725189,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.76,35.53,16155,58,16235,0.0035725285,11701,13680,25430,0.5379473063,2,74,74,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_006",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",10762,5969,16749,0.3563794853,0,1,0,0,1,1,1,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.6,35.41,4926,16,4947,0.0032342834,5836,5953,11802,0.5044060329,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_050",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8180,16770,24971,0.6715790317,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.84,35.23,8142,46,8198,0.0056111247,38,16724,16773,0.9970786383,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_037",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",21297,7437,28778,0.2584265759,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.73,35.54,12822,62,12909,0.0048028507,8475,7375,15869,0.4647425799,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_038",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",28897,11358,40321,0.2816894422,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.76,35.57,17462,67,17567,0.0038139694,11435,11291,22754,0.4962204448,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_053",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",23874,9973,33902,0.2941714353,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.66,35.3,13856,60,13939,0.0043044695,10018,9913,19963,0.496568652,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_011",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",28154,10145,38351,0.26453026,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.64,35.39,17092,61,17180,0.0035506403,11062,10084,21171,0.4763119361,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_055",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",23500,10307,33868,0.3043285697,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.65,35.16,13083,62,13168,0.004708384,10417,10245,20700,0.4949275362,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_090",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11871,3561,15455,0.2304108703,1,1,0,0,1,1,0,0,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.8,35.31,7306,23,7342,0.0031326614,4565,3538,8113,0.4360902256,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_058",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11019,17206,28264,0.6087602604,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.82,35.15,10955,34,11004,0.0030897855,64,17172,17260,0.9949015064,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_012",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",12323,5290,17637,0.2999376311,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.65,35.31,6926,19,6956,0.0027314549,5397,5271,10681,0.4934931186,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_060",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",16371,5640,22041,0.2558867565,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.66,34.69,9880,45,9935,0.0045294414,6491,5595,12106,0.4621675202,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_040",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",24080,36019,60189,0.5984316071,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.87,35.55,24024,98,24184,0.004052266,56,35921,36005,0.9976669907,2,74,74,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_013",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",4780,6349,11151,0.5693659761,1,1,1,0,1,1,1,1,7,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.81,35.41,4749,17,4778,0.003557974,31,6332,6373,0.9935666091,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_091",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",7860,3579,11465,0.3121674662,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.8,35.34,4428,12,4458,0.00269179,3432,3567,7007,0.5090623662,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_061",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",18293,6568,24902,0.2637539153,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.66,34.75,11101,21,11148,0.001883746,7192,6547,13754,0.4760069798,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_062",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",14671,5378,20096,0.2676154459,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.61,34.66,8945,31,8997,0.003445593,5726,5347,11099,0.4817551131,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_064",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8105,4484,12608,0.3556472081,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.59,34.72,3985,18,4005,0.004494382,4120,4466,8603,0.5191212368,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_067",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",28460,7236,35756,0.2023716299,1,1,0,0,1,1,0,0,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.67,34.55,20524,64,20620,0.0031037827,7936,7172,15136,0.4738372093,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_068",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",19966,6536,26540,0.2462697815,1,1,0,0,1,1,0,0,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.64,34.66,13340,43,13396,0.0032099134,6626,6493,13144,0.4939896531,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_069",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",13399,15881,29328,0.5414961811,1,1,1,0,1,1,0,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.76,34.64,13358,34,13417,0.0025340985,41,15847,15911,0.9959776255,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_070",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",14605,4884,19519,0.2502177366,1,1,0,0,1,1,1,0,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.64,34.7,9732,21,9768,0.0021498771,4873,4863,9751,0.4987180802,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_071",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",10919,4314,15256,0.2827739906,0,1,0,0,1,1,1,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.66,34.6,6786,32,6827,0.0046872711,4133,4282,8429,0.5080080674,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_072",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",9833,4359,14214,0.3066694808,0,1,0,0,1,1,1,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.6,34.68,4775,10,4792,0.0020868114,5058,4349,9422,0.4615792825,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_073",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",9335,4716,14076,0.3350383632,0,1,0,0,1,1,1,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.61,34.61,4818,9,4835,0.0018614271,4517,4707,9241,0.5093604588,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_074",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",5549,7916,13489,0.5868485433,1,1,1,0,1,1,1,1,7,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.84,34.55,5538,14,5564,0.0025161754,11,7902,7925,0.9970977918,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_076",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",20447,6465,26976,0.2396574733,1,1,0,0,1,1,0,0,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.65,34.69,14038,60,14139,0.0042435816,6409,6405,12837,0.4989483524,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_078",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",17214,7186,24438,0.2940502496,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.63,34.7,11169,30,11214,0.0026752274,6045,7156,13224,0.5411373261,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_079",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",5912,8411,14351,0.5860915616,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.77,34.61,5884,25,5918,0.0042244001,28,8386,8433,0.9944266572,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_080",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",15068,6021,21120,0.2850852273,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.6,34.61,7951,20,7985,0.0025046963,7117,6001,13135,0.4568709555,2,74,74,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_083",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",23730,7215,31000,0.2327419355,0,1,0,0,1,1,0,0,3,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.65,34.79,15831,58,15913,0.0036448187,7899,7157,15087,0.4743819182,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_087",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11784,17850,29692,0.6011720329,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.78,34.68,11743,41,11822,0.0034681103,41,17809,17870,0.9965864578,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_095",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",7278,9306,16604,0.5604673573,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.88,35.41,6939,32,6978,0.0045858412,339,9274,9626,0.9634323707,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_096",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",13897,5497,19423,0.2830149822,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.83,35.33,8355,21,8383,0.0025050698,5542,5476,11040,0.4960144928,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_097",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",14801,5049,19885,0.2539099824,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.82,35.34,8378,30,8423,0.0035616764,6423,5019,11462,0.437881696,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_098",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",10738,4794,15559,0.3081174883,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.83,35.33,5768,21,5796,0.0036231884,4970,4773,9763,0.4888866127,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_099",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",7474,3072,10555,0.2910468972,1,1,0,0,1,1,1,1,6,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.79,35.42,4351,17,4372,0.0038883806,3123,3055,6183,0.4940967168,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_103",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",8219,9828,18076,0.5437043594,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.89,35.37,8193,29,8238,0.0035202719,26,9799,9838,0.9960357796,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_104",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",15663,6225,21927,0.2838965659,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.82,35.36,9466,24,9505,0.0025249868,6197,6201,12422,0.4991949767,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_106",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",3144,13386,16554,0.8086263139,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.88,35.36,3112,19,3135,0.0060606061,32,13367,13419,0.9961248975,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_108",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",11421,15275,26745,0.5711347915,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.9,35.33,11369,29,11425,0.0025382932,52,15246,15320,0.9951697128,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_110",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",19925,8255,28221,0.2925126679,0,1,0,0,1,1,0,1,4,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.8,35.45,12058,32,12100,0.0026446281,7867,8223,16121,0.5100800198,2,74,74,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_111",4,106196951,"A","G","TET2","ENST00000380013","missense_variant","Ata/Gta|p.Ile1762Val/c.5284A>G",16889,6614,23541,0.2809566289,1,1,0,0,1,1,0,1,5,37.335,"NO","COSM3760322","haematopoietic_and_lymphoid_tissue, prostate, thyroid","2, 5, 1","rs2454206","rs2454206","NO",0.272,"NO","YES",0.041,"Tolerated",35.8,35.34,10566,44,10632,0.00413845,6323,6570,12909,0.5089472461,2,74,74,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_004",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",1214,1643,2864,0.5736731844,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.22,35.05,779,1032,1814,0.5689084895,435,611,1050,0.5819047619,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_046",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",11770,14206,26055,0.5452312416,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.35,35.18,3927,6574,10565,0.622243256,7843,7632,15490,0.4927049709,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_034",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",3628,3557,7197,0.4942337085,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.39,35.53,1529,1516,3051,0.4968862668,2099,2041,4146,0.4922817173,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_036",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",24476,20411,44960,0.4539813167,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.41,35.42,11574,9098,20704,0.4394319938,12902,11313,24256,0.466400066,2,108,108,"Polymorphism"]
["2nd Illumina, ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_006",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",6971,9754,16750,0.5823283582,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.49,35.36,924,4015,4947,0.8116029917,6047,5739,11803,0.4862323138,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_090",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",8733,6661,15409,0.4322798365,1,1,0,1,1,1,1,1,7,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.4,35.37,3991,3328,7328,0.4541484716,4742,3333,8081,0.4124489543,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_063",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",10521,10682,21235,0.5030374382,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.19,35.08,4864,4744,9626,0.4928319136,5657,5938,11609,0.5114996985,2,108,108,"Polymorphism"]
["ESP6500, dbSNP, ExAC, freq, many samples","UPN_Tr2_065",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",9893,9521,19460,0.4892600206,1,1,1,1,1,1,1,1,8,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.15,34.95,5429,5255,10713,0.4905255297,4464,4266,8747,0.487710072,2,108,108,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_014",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",3290,3284,6595,0.4979529947,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.58,34.34,3290,3284,6595,0.4979529947,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_018",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",2243,2136,4385,0.4871151653,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.52,34.4,2243,2136,4385,0.4871151653,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_019",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",2570,2518,5092,0.4945011783,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.47,34.47,2570,2518,5092,0.4945011783,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_089",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",3080,3043,6132,0.4962491846,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.41,34.67,3080,3043,6132,0.4962491846,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_042",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",4376,4369,8772,0.4980620155,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.52,34.02,4376,4369,8772,0.4980620155,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_043",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",3500,3584,7106,0.5043625106,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.46,33.93,3500,3584,7106,0.5043625106,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_031",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",2285,2185,4474,0.488377291,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.59,34.27,2285,2185,4474,0.488377291,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_036",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",3546,4719,8285,0.5695835848,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.44,34.34,3546,4719,8285,0.5695835848,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_038",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",5631,5676,11340,0.5005291005,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.56,34.28,5631,5676,11340,0.5005291005,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_039",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",4667,1767,6444,0.2742085661,1,1,1,1,1,0,0,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.6,34.31,4667,1767,6444,0.2742085661,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_060",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",6443,5979,12443,0.4805111308,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.9,34.12,6443,5979,12443,0.4805111308,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_092",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",2028,2200,4239,0.5189903279,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.57,34.76,2028,2200,4239,0.5189903279,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_063",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",5905,6132,12065,0.5082469954,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.96,34.1,5905,6132,12065,0.5082469954,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_066",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",14173,13793,28025,0.4921677074,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.93,34.15,14173,13793,28025,0.4921677074,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_075",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",7974,7577,15566,0.4867660285,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.81,34.12,7974,7577,15566,0.4867660285,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_076",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",7091,6464,13585,0.4758189179,1,1,1,1,1,0,1,1,7,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.94,34.03,7091,6464,13585,0.4758189179,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_079",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",4282,4235,8534,0.4962502929,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",33.95,34.18,4282,4235,8534,0.4962502929,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_097",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",4247,1828,6089,0.3002134998,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.53,34.71,4247,1828,6089,0.3002134998,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_105",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",2881,2300,5188,0.4433307633,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.55,34.72,2881,2300,5188,0.4433307633,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_107",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",5534,5233,10794,0.4848063739,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.49,34.68,5534,5233,10794,0.4848063739,0,0,0,"NA",1,22,22,"Polymorphism"]
["dbSNP, freq, many samples","UPN_Tr2_110",7,148525904,"C","G","EZH2","ENST00000320356","missense_variant","Gac/Cac|p.Asp185His/c.553G>C",3686,3734,7423,0.5030311195,1,1,0,1,1,0,1,1,6,"NO","NO","COSM3762469","soft_tissue, thyroid","3, 1","rs2302427","rs2302427","NO","NO","NO","YES",-1.884,"Tolerated",34.53,34.65,3686,3734,7423,0.5030311195,0,0,0,"NA",1,22,22,"Polymorphism"]
["2nd Illumina, 1000G, neutral effect, freq","UPN_Tr2_001","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",687,641,689,0.9303338171,1,1,1,1,1,1,0,1,7,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",35.09,"NA",0,0,0,"NA",687,641,689,0.9303338171,1,6,6,"Polymorphism"]
["1000G, neutral effect, freq","UPN_Tr2_010","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",3506,1655,3520,0.4701704545,1,1,1,1,1,1,0,1,7,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",34.84,"NA",0,0,0,"NA",3506,1655,3520,0.4701704545,1,6,6,"Polymorphism"]
["1000G, neutral effect, freq","UPN_Tr2_063","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",954,871,963,0.9044652129,1,1,1,1,1,1,0,1,7,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",34.59,"NA",0,0,0,"NA",954,871,963,0.9044652129,1,6,6,"Polymorphism"]
["1000G, neutral effect, freq","UPN_Tr2_070","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",1564,1431,1574,0.9091486658,1,1,1,1,1,1,0,1,7,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",34.69,"NA",0,0,0,"NA",1564,1431,1574,0.9091486658,1,6,6,"Polymorphism"]
["1000G, neutral effect, freq","UPN_Tr2_075","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",1189,1077,1193,0.9027661358,1,1,1,1,1,1,0,1,7,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",34.46,"NA",0,0,0,"NA",1189,1077,1193,0.9027661358,1,6,6,"Polymorphism"]
["1000G, neutral effect, freq","UPN_Tr2_080","X",15841230,"C","CAGCCGG","ZRSR2","ENST00000307771","disruptive_inframe_insertion","cgc/cgGAGCCGc|p.Arg448_Arg449insSerArg/c.1338_1343dupGAGCCG",809,744,811,0.9173859433,1,1,0,1,1,1,0,1,6,"NO",0.0209,"NO","NO","O","NO","NO","NO","NO","NO","NO",0.745,"Tolerated",34.83,"NA",0,0,0,"NA",809,744,811,0.9173859433,1,6,6,"Polymorphism"]
["ExAC, freq, dbsnp, ESP6500","UPN_Tr2_004",4,106156478,"C","T","TET2","ENST00000380013","missense_variant","tCc/tTc|p.Ser460Phe/c.1379C>T",833,863,1705,0.5061583578,1,1,1,1,1,1,1,1,8,0.0116,"NO","COSM53247, COSM2952717","haematopoietic_and_lymphoid_tissue",3,"NO","rs376570662","NO",0.0001071,"NO","NO",-1.29,"Tolerated",34.51,34.08,417,426,850,0.5011764706,416,437,855,0.5111111111,0.8081214825,2,2,"Polymorphism"]
[{"$nulls":14},{"$f":"SUM(O2:O402)","v":362},{"$f":"SUM(P2:P402)","v":401},{"$f":"SUM(Q2:Q402)","v":217},{"$f":"SUM(R2:R402)","v":314},{"$f":"SUM(S2:S402)","v":401},{"$f":"SUM(T2:T402)","v":214},{"$f":"SUM(U2:U402)","v":335},{"$f":"SUM(V2:V402)","v":390}]

{"sheet":"FN Mutations","index":3,"n_rows":13,"n_cols":50,"rows_kept":13,"cut":false,"hidden":false,"merged":[]}
["True because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["Hotspot, inspected","UPN_Tr2_095",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",7332,100,7468,0.0133904659882164,0,0,0,0,1,1,0,1,3,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.17,34.3,3690,50,3755,0.0133155792276964,3642,50,3713,0.0134661998384056,1,6,6,"Artifact (0)"]
["Inspected","UPN_Tr2_048",2,198267702,"C","T","SF3B1","ENST00000335508","missense_variant","Ggc/Agc|p.Gly593Ser/c.1777G>A",747,29,777,0.0373230373230373,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.808,"Deleterious",33.81,32.03,0,0,0,"NA",747,29,777,0.0373230373230373,1,1,1,"Artifact (0)"]
["Inspected","UPN_Tr2_071",4,106180845,"G","A","TET2","ENST00000380013","stop_gained","tgG/tgA|p.Trp1291*/c.3873G>A",5750,274,6038,0.0453792646571713,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.05,34.89,5750,274,6038,0.0453792646571713,0,0,0,"NA",1,1,1,"Artifact (1)"]
["Inspected","UPN_Tr2_048",4,106197197,"G","A","TET2","ENST00000380013","missense_variant","Gat/Aat|p.Asp1844Asn/c.5530G>A",567,28,598,0.0468227424749164,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.608,"Deleterious",33.99,33.07,227,13,242,0.0537190082644628,340,15,356,0.0421348314606742,0.555890040493824,1,1,"Artifact (1)"]
["2nd Illumina, inspected","UPN_Tr2_086",4,106197360,"CCCTCG","C","TET2","ENST00000380013","frameshift_variant","tccctcgtc/|p.Val1900fs/c.5694_5698delCCTCG",12023,478,12556,0.0380694488690666,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.42,"NA",6091,242,6345,0.038140267927502,5932,236,6211,0.0379971019159556,1,1,1,"Artifact (0)"]
["Inspected, IonT_1 validated","UPN_Tr2_039",4,106197504,"G","A","TET2","ENST00000380013","missense_variant","gGc/gAc|p.Gly1946Asp/c.5837G>A",21410,1176,22630,0.0519664162615996,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.483,"Deleterious",34.79,34.69,21410,1176,22630,0.0519664162615996,0,0,0,"NA",1,1,1,"Artifact (0)"]
["Expert, Cosmic, prediction, bq","UPN_Tr2_048",17,7577128,"A","T","TP53","ENST00000269305","missense_variant","ttT/ttA|p.Phe270Leu/c.810T>A",12904,143,13115,0.0109035455585208,0,0,0,0,1,1,0,1,3,"NO","NO","COSM5369801, COSM5369800, COSM44156, COSM5369802","large_intestine, lung, oesophagus, urinary_tract","1, 1, 2, 1","NO","NO","NO","NO","NO","NO",-4.291,"Deleterious",35.35,33.58,12664,73,12805,0.00570089808668489,240,70,310,0.225806451612903,2,1,1,"Artifact (0)"]
["Expert, bq, Cosmic, freq","UPN_Tr2_103",17,7579514,"G","A","TP53","ENST00000269305","missense_variant","cCa/cTa|p.Pro58Leu/c.173C>T",8518,1527,10089,0.151352958667856,0,1,0,0,1,1,0,0,3,"NO","NO","COSM43677","oesophagus",1,"NO","NO","NO","NO","NO","NO",0.483,"Tolerated",34.92,35.33,6989,10,7036,0.00142126208072769,1529,1517,3053,0.496888306583688,2,1,1,"Artifact (0)"]
["inspected","UPN_Tr2_071",17,74732998,"C","T","SRSF2","ENST00000392485","missense_variant","gGc/gAc|p.Gly82Asp/c.245G>A",805,48,854,0.0562060889929742,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.172,"Deleterious",32.4,30.23,406,24,430,0.0558139534883721,399,24,424,0.0566037735849057,1,1,1,"Artifact (0)"]
["inspected","UPN_Tr2_034",20,31022874,"A","AT","ASXL1","ENST00000375687","frameshift_variant","act/aTct|p.Thr787fs/c.2359_2360insT",3025,440,3058,0.143884892086331,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.32,"NA",140,0,142,0,2885,440,2916,0.150891632373114,5.95214893179136E-009,1,1,"Artifact (0)"]
["Expert, bq, prediction","UPN_Tr2_041",20,31025059,"T","A","ASXL1","ENST00000375687","missense_variant","aTg/aAg|p.Met1515Lys/c.4544T>A",6046,125,6537,0.0191219213706593,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.18,"Deleterious",31.73,32.45,205,60,265,0.226415094339623,5841,65,6272,0.0103635204081633,2,1,112,"Artifact (1)"]
[{"$nulls":14},{"$f":"SUM(O2:O12)","v":0},{"$f":"SUM(P2:P12)","v":2},{"$f":"SUM(Q2:Q12)","v":0},{"$f":"SUM(R2:R12)","v":2},{"$f":"SUM(S2:S12)","v":11},{"$f":"SUM(T2:T12)","v":6},{"$f":"SUM(U2:U12)","v":0},{"$f":"SUM(V2:V12)","v":9}]

{"sheet":"FN Polymorphisms","index":4,"n_rows":1,"n_cols":50,"rows_kept":1,"cut":false,"hidden":false,"merged":[]}
["Comments","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]

{"sheet":"FP Mutations","index":5,"n_rows":41,"n_cols":50,"rows_kept":41,"cut":false,"hidden":false,"merged":[]}
["Artifact because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["Hotspot, inspected, low freq, many artifacts","UPN_Tr2_049",1,115258744,"C","A","NRAS","ENST00000369535","missense_variant","gGt/gTt|p.Gly13Val/c.38G>T",22091,323,22697,0.014230955632903,0,0,0,0,1,0,0,1,2,"NO","NO","COSM574","adrenal_gland, central_nervous_system, haematopoietic_and_lymphoid_tissue, large_intestine, skin, soft_tissue","1, 1, 48, 4, 18, 1","NO","rs121434596","YES","NO","NO","NO",-7.664,"Deleterious",34.8,28.67,22091,323,22697,0.014230955632903,0,0,0,"NA",1,2,3,"Hotspot (-2)"]
["low freq, many artifacts","UPN_Tr2_049",1,115258744,"C","T","NRAS","ENST00000369535","missense_variant","gGt/gAt|p.Gly13Asp/c.38G>A",22091,230,22697,0.010133497819095,0,0,0,0,1,0,0,1,2,"NO","NO","COSM573","endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, NS, skin, thyroid, upper_aerodigestive_tract","1, 217, 10, 278, 26, 1, 2","NO","rs121434596","YES",8.236E-006,"NO","NO",-5.441,"Deleterious",34.8,34.69,22091,230,22697,0.010133497819095,0,0,0,"NA",1,1,3,"Hotspot (-2)"]
["inspected, low coverage, common artifact","UPN_Tr2_064",2,25505540,"G","A","DNMT3A","ENST00000264709","missense_variant","tCc/tTc|p.Ser73Phe/c.218C>T",90,27,117,0.230769230769231,0,1,1,1,1,1,1,1,7,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.426,"Tolerated",31.97,35.11,45,13,58,0.224137931034483,45,14,59,0.23728813559322,1,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_056",4,106155784,"A","G","TET2","ENST00000380013","missense_variant","Aca/Gca|p.Thr229Ala/c.685A>G",925,127,1062,0.119585687382298,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.049,"Tolerated",32.85,33.87,352,63,417,0.151079136690647,573,64,645,0.0992248062015504,0.0152881822262494,3,3,"Probably True (-4)"]
["inspected, bad alignment","UPN_Tr2_002",4,106157716,"ATCCCAAAGCAAGATCT","A","TET2","ENST00000380013","frameshift_variant","ccaaagcaagatcttctt/|p.Pro874fs/c.2620_2635delCCAAAGCAAGATCTTC",17087,2528,19709,0.128266274290933,1,1,0,1,0,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.14,"NA",8489,1246,9792,0.127246732026144,8598,1282,9917,0.129272965614601,0.717184985226247,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_044",4,106190900,"C","T","TET2","ENST00000380013","missense_variant","aCa/aTa|p.Thr1393Ile/c.4178C>T",781,40,824,0.0485436893203883,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4383944","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-5.849,"Deleterious",32.53,34.1,0,0,0,"NA",781,40,824,0.0485436893203883,1,1,1,"Probably True (-1)"]
["low freq, many artifacts","UPN_Tr2_002",4,106193838,"GC","G","TET2","ENST00000380013","frameshift_variant","gct/|p.Ala1434fs/c.4301delC",10716,1277,12026,0.106186595709297,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.76,"NA",5381,635,6029,0.105324266047437,5335,642,5997,0.107053526763382,0.744779980895702,1,1,"Probably True (-5)"]
["inspected, bad alignment","UPN_Tr2_090",4,106196245,"G","GCCCA","TET2","ENST00000380013","frameshift_variant","cag/cCCACag|p.Gln1527fs/c.4579_4580insCCAC",7368,399,7395,0.0539553752535497,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.91,"NA",2776,399,2782,0.143421998562185,4592,0,4613,0,2,5,5,"Probably True (-2)"]
["inspected","UPN_Tr2_048",7,148512065,"G","A","EZH2","ENST00000320356","missense_variant","tCg/tTg|p.Ser538Leu/c.1613C>T",964,36,1003,0.0358923230309073,0,0,0,0,1,0,0,1,2,"NO","NO","COSM122927","skin, upper_aerodigestive_tract","1, 1","NO","NO","NO","NO","NO","NO",-3.584,"Deleterious",34.08,35.67,964,36,1003,0.0358923230309073,0,0,0,"NA",1,1,1,"Probably True (-1)"]
["inspected, not in 2nd illumina, not in 454","UPN_Tr2_006",7,148544336,"C","T","EZH2","ENST00000320356","missense_variant","Gta/Ata|p.Val19Ile/c.55G>A",275,40,316,0.126582278481013,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.653,"Tolerated",32.62,34.72,137,20,158,0.126582278481013,138,20,158,0.126582278481013,1,1,1,"Probably True (-4)"]
["low freq, many artifacts","UPN_Tr2_064",9,5073771,"T","A","JAK2","ENST00000381652","missense_variant","gTc/gAc|p.Val617Asp/c.1850T>A",2639,34,2684,0.0126676602086438,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.792,"Deleterious",31.36,30.47,1311,20,1336,0.0149700598802395,1328,14,1348,0.0103857566765579,0.305598720790307,1,1,"Hotspot (-1)"]
["low freq, many artifacts","UPN_Tr2_056",12,25398270,"T","C","KRAS","ENST00000256078","missense_variant","Agt/Ggt|p.Ser17Gly/c.49A>G",1652,34,1686,0.0201660735468565,0,0,0,0,1,1,0,1,3,"NO","NO","COSM540","pancreas",1,"NO","NO","NO","NO","NO","NO",-3.541,"Deleterious",33.71,31.82,835,18,853,0.0211019929660023,817,16,833,0.0192076830732293,0.863110208799123,1,1,"Probably True (-1)"]
["Not in 2nd illumina, inspected, many artifacts","UPN_Tr2_006",17,7573978,"A","T","TP53","ENST00000269305","missense_variant","cTc/cAc|p.Leu350His/c.1049T>A",697,55,754,0.0729442970822281,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.773,"Deleterious",33.89,35.53,697,55,754,0.0729442970822281,0,0,0,"NA",1,1,1,"Probably True (-2)"]
["inspected, many artifacts, ins and del","UPN_Tr2_022",17,7574002,"CG","C","TP53","ENST00000269305","frameshift_variant","cga/|p.Arg342fs/c.1024delC",4835,796,5652,0.140835102618542,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.32,"NA",2437,410,2857,0.143507175358768,2398,386,2795,0.138103756708408,0.566363649545187,1,1,"Probably True (-5)"]
["inspected","UPN_Tr2_044",17,7577070,"G","A","TP53","ENST00000269305","missense_variant","Cgc/Tgc|p.Arg290Cys/c.868C>T",3038,70,3120,0.0224358974358974,0,0,0,0,1,0,0,1,2,"NO","NO","COSM45679, COSM3522691, COSM3522692, COSM1167879","haematopoietic_and_lymphoid_tissue, skin, thyroid, upper_aerodigestive_tract","1, 11, 1, 1","NO","NO","NO",2.471E-005,"NO","NO",-3.836,"Deleterious",33.61,33.96,0,0,0,"NA",3038,70,3120,0.0224358974358974,1,1,1,"Probably True (-1)"]
["inspected, many artifacts","UPN_Tr2_043",17,7577098,"T","G","TP53","ENST00000269305","missense_variant","agA/agC|p.Arg280Ser/c.840A>C",7736,399,8188,0.0487298485588666,0,0,0,0,1,0,0,1,2,"NO","NO","COSM1582360, COSM44233","stomach, lung, oesophagus, upper_aerodigestive_tract","2, 2, 1, 1","NO","NO","NO","NO","NO","NO",-5.754,"Deleterious",32.66,34.12,0,0,0,"NA",7736,399,8188,0.0487298485588666,1,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_103",17,7577108,"C","T","TP53","ENST00000269305","missense_variant","tGt/tAt|p.Cys277Tyr/c.830G>A",5931,205,6154,0.0333116672083198,0,0,0,0,1,0,0,1,2,"NO","NO","COSM43737","bone, breast, haematopoietic_and_lymphoid_tissue, large_intestine, liver, oesophagus, peritoneum, skin, stomach, urinary_tract","2, 1, 2, 1, 1, 2, 1, 1, 2, 2","NO","NO","NO","NA","NO","NO",-10.564,"Deleterious",34.3,35.4,0,0,0,"NA",5931,205,6154,0.0333116672083198,1,1,1,"Probably True (-1)"]
["inspected, many artifacts","UPN_Tr2_041",17,7577140,"TC","T","TP53","ENST00000269305","frameshift_variant","gga/|p.Gly266fs/c.797delG",2794,89,2932,0.0303547066848568,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.48,"NA",2688,88,2825,0.0311504424778761,106,1,107,0.00934579439252336,2,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_098",17,7578452,"TGGCGCG","T","TP53","ENST00000269305","inframe_deletion","cgcgcc/|p.Arg158_Ala159del/c.472_477delCGCGCC",5076,111,5210,0.0213051823416507,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-14.414,"Deleterious",33.53,"NA",5076,111,5210,0.0213051823416507,0,0,0,"NA",1,1,1,"Probably True (-1)"]
["low bq, many samples, no database","UPN_Tr2_086",17,7578502,"A","T","TP53","ENST00000269305","missense_variant","gTg/gAg|p.Val143Glu/c.428T>A",2068,184,2259,0.081451969898185,0,0,0,1,1,1,0,1,4,"NO","NO","COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1","NO","NO","NO","NO","NO","NO",-5.68,"Deleterious",31.68,26.43,1,86,87,0.988505747126437,2067,98,2172,0.0451197053406998,4.85671666357853E-102,45,45,"Probably True (-2)"]
["homopolymer 6G, low freq, many samples","UPN_Tr2_071",17,74732955,"CG","C","SRSF2","ENST00000392485","frameshift_variant","ccg/|p.Pro96fs/c.287delC",816,36,854,0.0421545667447307,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.01,"NA",413,18,432,0.0416666666666667,403,18,422,0.042654028436019,1,23,30,"Hotspot (-1)"]
["inspected, not in 2nd illumina, not in 454","UPN_Tr2_006",19,33792509,"G","A","CEBPA","ENST00000498907","missense_variant","gCg/gTg|p.Ala271Val/c.812C>T",0,91,91,1,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.175,"Tolerated",0,33.87,0,45,45,1,0,46,46,1,1,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_044",19,33792624,"G","A","CEBPA","ENST00000498907","missense_variant","Ccc/Tcc|p.Pro233Ser/c.697C>T",46,23,69,0.333333333333333,1,1,1,1,1,0,1,1,7,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.157,"Deleterious",35.54,35.83,0,0,0,"NA",46,23,69,0.333333333333333,1,1,2,"Probably True (-6)"]
["inspected","UPN_Tr2_044",19,33792645,"TG","T","CEBPA","ENST00000498907","frameshift_variant","ccc/|p.Thr226fs/c.675delC",320,30,350,0.0857142857142857,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.07,"NA",251,30,281,0.106761565836299,69,0,69,0,2,1,1,"Probably True (-1)"]
["inspected, low coverage, problematic area","UPN_Tr2_011",19,33792837,"G","T","CEBPA","ENST00000498907","missense_variant","Cag/Aag|p.Gln162Lys/c.484C>A",78,55,133,0.413533834586466,1,1,1,0,1,0,1,1,6,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.547,"Tolerated",35.24,35.53,0,55,55,1,78,0,78,0,2,1,1,"Probably True (-4)"]
["inspected","UPN_Tr2_056",19,33792957,"C","A","CEBPA","ENST00000498907","missense_variant","Ggg/Tgg|p.Gly122Trp/c.364G>T",53,26,79,0.329113924050633,1,1,1,1,1,1,1,1,8,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.823,"Tolerated",31.19,28.62,26,13,39,0.333333333333333,27,13,40,0.325,1,1,1,"Probably True (-4)"]
["low freq, bad alignment, many artifacts","UPN_Tr2_048",19,33793075,"G","T","CEBPA","ENST00000498907","missense_variant","ttC/ttA|p.Phe82Leu/c.246C>A",1765,46,1813,0.0253723110865968,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.666,"Deleterious",35.58,34.39,1748,46,1796,0.0256124721603563,17,0,17,0,2,1,1,"Probably True (-1)"]
["inspected","UPN_Tr2_044",19,33793133,"T","A","CEBPA","ENST00000498907","missense_variant","gAc/gTc|p.Asp63Val/c.188A>T",309,24,336,0.0714285714285714,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.495,"Deleterious",33.76,27.17,309,24,336,0.0714285714285714,0,0,0,"NA",1,1,1,"Probably True (-2)"]
["Inspected, homopolymer 6G, del and ins","UPN_Tr2_039",19,33793252,"C","CG","CEBPA","ENST00000498907","frameshift_variant","ccg/ccCg|p.His24fs/c.68dupC",832,62,834,0.0743405275779376,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","rs137852729","YES","NO","NO","NO","NA","NA",34.75,"NA",0,0,0,"NA",832,62,834,0.0743405275779376,1,2,8,"Probably True (-3)"]
["inspected, strandbias","UPN_Tr2_055",20,31022598,"C","T","ASXL1","ENST00000375687","stop_gained","Caa/Taa|p.Gln695*/c.2083C>T",25724,1603,27363,0.0585827577385521,1,0,0,0,1,1,0,0,3,"NO","NO","COSM1012894","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",35.46,35.42,11132,18,11163,0.00161246976619188,14592,1585,16200,0.0978395061728395,2,1,1,"Probably True (-1)"]
["inspected, bad alignment, different dels","UPN_Tr2_110",20,31023026,"GA","G","ASXL1","ENST00000375687","frameshift_variant","aag/|p.Lys838fs/c.2513delA",25562,4296,30545,0.140644950073662,1,1,0,1,1,1,0,1,6,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.62,"NA",13661,2348,16069,0.146119858111892,11901,1948,14476,0.134567560099475,0.141211243208061,1,2,"Probably True (-4)"]
["inspected, many artifacts!","UPN_Tr2_051",21,36164601,"G","A","RUNX1","ENST00000437180","missense_variant","cCg/cTg|p.Pro425Leu/c.1274C>T",3351,179,3532,0.0506795016987542,0,0,0,0,1,0,0,1,2,"NO","NO","COSM87293","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-7.64,"Deleterious",32.99,31.89,3349,179,3530,0.0507082152974504,2,0,2,0,1,1,1,"Probably True (-1)"]
["inspected, many artifacts","UPN_Tr2_049",21,36164660,"C","CA","RUNX1","ENST00000437180","frameshift_variant","ctg/ctTg|p.Tyr406fs/c.1214dupT",4090,277,4201,0.0659366817424423,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.47,"NA",772,39,875,0.0445714285714286,3318,238,3326,0.0715574263379435,0.0461403795913947,1,1,"Probably True (-3)"]
["inspected, many artifacts","UPN_Tr2_071",21,36164664,"T","TG","RUNX1","ENST00000437180","frameshift_variant","cac/cCac|p.His404fs/c.1210dupC",346,29,415,0.0698795180722892,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",19.87,"NA",105,9,157,0.0573248407643312,241,20,258,0.0775193798449612,1,1,5,"Probably True (-2)"]
["inspected, many artifacts","UPN_Tr2_025",21,36206774,"C","CGTGGGGGCTGGGTG","RUNX1","ENST00000437180","frameshift_variant","acg/acCACCCAGCCCCCACg|p.Pro247fs/c.724_737dupCACCCAGCCCCCAC",4049,460,4233,0.108669974013702,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.62,"NA",2546,460,2550,0.180392156862745,1503,0,1683,0,3.20475953820114E-087,1,1,"Probably True (-3)"]
["low freq, many artifacts","UPN_Tr2_006",21,44524457,"A","G","U2AF1","ENST00000291552","missense_variant","Tct/Cct|p.Ser34Pro/c.100T>C",5489,61,5563,0.0109653064893043,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.883,"Deleterious",33.87,33.9,2767,30,2799,0.0107181136120043,2722,31,2764,0.0112156295224313,0.897907824993934,1,1,"Hotspot (-1)"]
["low freq, many artifacts","UPN_Tr2_044","X",15821911,"G","T","ZRSR2","ENST00000307771","stop_gained","Gaa/Taa|p.Glu102*/c.304G>T",732,85,825,0.103030303030303,0,1,0,0,1,1,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.8,33.06,368,41,413,0.099273607748184,364,44,412,0.106796116504854,0.732550970409834,1,1,"Probably True (-1)"]
["low freq, neutral effect","UPN_Tr2_041","X",15840959,"T","C","ZRSR2","ENST00000307771","missense_variant","tTg/tCg|p.Leu348Ser/c.1043T>C",410,86,501,0.171656686626747,0,1,0,1,1,1,0,1,5,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.188,"Tolerated",33.26,31.42,207,44,252,0.174603174603175,203,42,249,0.168674698795181,1,2,2,"Probably True (-3)"]
["inspected, many artifacts","UPN_Tr2_036","X",15841158,"TCGGGAGAGGCACAATTCACGAAGCAGAGGAAGAAATAGGGACCGCAGCAGGGACCGCAGCCGGGGCCGGGGCAGCCGGAGCCGGAGCCGGAGCCGGAGCCGCAGGAGCCGCCGCAGC","T","ZRSR2","ENST00000307771","inframe_deletion","|p.Glu416_Arg454del/c.1246_1362del",2417,"NA",2427,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-46.247,"Deleterious",34.03,"NA",2381,"NA",2391,"NA",36,"NA",36,"NA",2,1,1,"Probably True (-1)"]
[{"$nulls":14},{"$f":"SUM(O2:O40)","v":12},{"$f":"SUM(P2:P40)","v":18},{"$f":"SUM(Q2:Q40)","v":5},{"$f":"SUM(R2:R40)","v":23},{"$f":"SUM(S2:S40)","v":37},{"$f":"SUM(T2:T40)","v":20},{"$f":"SUM(U2:U40)","v":5},{"$f":"SUM(V2:V40)","v":36}]

{"sheet":"FP Polymorphisms","index":6,"n_rows":2,"n_cols":50,"rows_kept":2,"cut":false,"hidden":false,"merged":[]}
["Artifact because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["many artifacts, strandbias, many samples","UPN_Tr2_004",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",376,102,480,0.2125,0,0,0,1,1,0,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",32.06,31.61,353,102,457,0.2231947484,23,0,23,0,0.0068595744,111,111,"Polymorphism"]

{"sheet":"TN Mutations Filter 2","index":7,"n_rows":8368,"n_cols":50,"rows_kept":1125,"cut":true,"hidden":false,"merged":[],"bounds":{"rows_first":500,"rows_last":125,"rows_between":500,"halvings":2}}
["Artifact because...","Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","provean_score","prediction","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","strandbias","nr_samples","nr_samples_similar","Category"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",1,115258692,"A","T","NRAS","ENST00000369535","missense_variant","gaT/gaA|p.Asp30Glu/c.90T>A",5602,61,5704,0.0106942496493689,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.367,"Tolerated",35,35.33,5602,61,5704,0.0106942496493689,0,0,0,"NA",1,1,1,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",1,115258720,"A","G","NRAS","ENST00000369535","missense_variant","aTc/aCc|p.Ile21Thr/c.62T>C",5607,87,5703,0.0152551288795371,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.942,"Deleterious",34.98,34.09,5607,87,5703,0.0152551288795371,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_020",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",8854,91,8987,0.0101257371759208,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.15,33.75,8854,91,8987,0.0101257371759208,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",14245,171,14483,0.0118069460747083,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.37,32.59,14245,171,14483,0.0118069460747083,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_045",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",24602,256,24983,0.010246967938198,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.37,32.32,24602,256,24983,0.010246967938198,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_032",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",6454,79,6554,0.0120537076594446,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.13,33.24,6454,79,6554,0.0120537076594446,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_046",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",22460,251,22796,0.0110107036322162,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.27,33.12,22460,251,22796,0.0110107036322162,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_049",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",22345,270,22702,0.0118932252664963,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.45,32.97,22345,270,22702,0.0118932252664963,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_039",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",13181,144,13374,0.0107671601615074,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",32.97,33.02,13181,144,13374,0.0107671601615074,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_053",1,115258733,"T","C","NRAS","ENST00000369535","missense_variant","Agc/Ggc|p.Ser17Gly/c.49A>G",23451,257,23807,0.0107951442852942,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.515,"Deleterious",33.39,33.12,23451,257,23807,0.0107951442852942,0,0,0,"NA",1,8,8,"Artifact (4)"]
["inspected, low freq","UPN_Tr2_044",2,25457148,"TTA","T","DNMT3A","ENST00000264709","frameshift_variant+stop_lost","taa/|p.Ter913fs/c.2737_2738delTA",2100,29,2140,0.0135514018691589,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.28,"NA",2100,29,2140,0.0135514018691589,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_069",2,25457191,"C","T","DNMT3A","ENST00000264709","missense_variant","cGc/cAc|p.Arg899His/c.2696G>A",1678,20,1701,0.0117577895355673,0,0,0,0,1,0,0,1,2,"NO","NO","COSM1583134","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-4.399,"Deleterious",34.9,35.6,1678,20,1701,0.0117577895355673,0,0,0,"NA",1,1,1,"Artifact (1)"]
["inspected, low freq, no database, many artifacts","UPN_Tr2_061",2,25457201,"G","A","DNMT3A","ENST00000264709","missense_variant","Cca/Tca|p.Pro896Ser/c.2686C>T",1949,20,1973,0.010136847440446,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.203,"Deleterious",34.69,28.75,1949,20,1973,0.010136847440446,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_069",2,25457215,"C","T","DNMT3A","ENST00000264709","missense_variant","cGg/cAg|p.Arg891Gln/c.2672G>A",3310,39,3357,0.0116175156389634,0,0,0,0,1,0,0,1,2,"NO","NO","COSM5133340","large_intestine",1,"NO","NO","NO","NO","NO","NO",-2.951,"Deleterious",31.12,33.21,1679,19,1701,0.0111699000587889,1631,20,1656,0.0120772946859903,0.872605078776721,1,1,"Artifact (2)"]
["inspected, low freq, no database, many artifacts","UPN_Tr2_068",2,25457239,"A","T","DNMT3A","ENST00000264709","stop_gained","tTg/tAg|p.Leu883*/c.2648T>A",2149,25,2186,0.0114364135407136,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.24,26.52,1088,8,1105,0.00723981900452489,1061,17,1081,0.0157261794634598,0.0717589016434184,1,1,"Artifact (3)"]
["Hotspot, inspected, bad alignment, many artifacts","UPN_Tr2_076",2,25457243,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg882Cys/c.2644C>T",3156,40,3206,0.0124766063630692,0,0,0,0,1,0,0,1,2,0.0465,"NO","COSM53042","haematopoietic_and_lymphoid_tissue, prostate","191, 1","NO","rs377577594","NO",0.0003624,"NO","NO",-6.901,"Deleterious",32.54,34.15,1593,20,1619,0.0123533045089561,1563,20,1587,0.0126023944549464,1,6,6,"Artifact (0)"]
["Inspected, not in 2nd Illumina, many artifacts","UPN_Tr2_013",2,25457248,"A","T","DNMT3A","ENST00000264709","missense_variant","aTg/aAg|p.Met880Lys/c.2639T>A",3443,52,3510,0.0148148148148148,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.206,"Deleterious",34.19,29.35,1740,20,1769,0.0113058224985868,1703,32,1741,0.0183802412406663,0.0939532619314844,1,1,"Artifact (2)"]
["Inspected, not in 2nd Illumina, many artifacts","UPN_Tr2_006",2,25457249,"T","C","DNMT3A","ENST00000264709","missense_variant","Atg/Gtg|p.Met880Val/c.2638A>G",4537,56,4601,0.0121712671158444,0,0,0,0,1,0,0,1,2,"NO","NO","COSM120499","haematopoietic_and_lymphoid_tissue",3,"NO","NO","NO",1.647E-005,"NO","NO",-3.078,"Deleterious",33.17,34.41,2275,28,2310,0.0121212121212121,2262,28,2291,0.0122217372326495,1,1,1,"Artifact (1)"]
["Inspected, not in 2nd Illumina, many artifacts","UPN_Tr2_006",2,25457261,"C","T","DNMT3A","ENST00000264709","missense_variant","Gac/Aac|p.Asp876Asn/c.2626G>A",4546,50,4601,0.0108672027820039,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.888,"Deleterious",33.32,30.68,2286,24,2310,0.0103896103896104,2260,26,2291,0.011348756001746,0.777609781491107,2,2,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_060",2,25457261,"C","T","DNMT3A","ENST00000264709","missense_variant","Gac/Aac|p.Asp876Asn/c.2626G>A",3323,38,3363,0.0112994350282486,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.888,"Deleterious",31.68,31.32,1670,19,1689,0.0112492599171107,1653,19,1674,0.0113500597371565,1,2,2,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_006",2,25458628,"GA","G","DNMT3A","ENST00000264709","frameshift_variant","ttt/|p.Pro849fs/c.2543delT",6442,67,6561,0.0102118579484835,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.42,"NA",6442,67,6561,0.0102118579484835,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_006",2,25458693,"A","T","DNMT3A","ENST00000264709","missense_variant","tTc/tAc|p.Phe827Tyr/c.2480T>A",12819,139,12997,0.0106947757174733,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.7,"Tolerated",33.82,29.98,6472,57,6549,0.0087036188731104,6347,82,6448,0.0127171215880893,0.0267346868689851,1,1,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25459852,"C","T","DNMT3A","ENST00000264709","missense_variant","Gat/Aat|p.Asp811Asn/c.2431G>A",3521,55,3581,0.0153588383133203,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.198,"Deleterious",34.67,34.89,3521,55,3581,0.0153588383133203,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",2,25459869,"A","T","DNMT3A","ENST00000264709","stop_gained","tTg/tAg|p.Leu805*/c.2414T>A",1466,54,1524,0.0354330708661417,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.84,34.11,1466,54,1524,0.0354330708661417,0,0,0,"NA",1,1,1,"Artifact (1)"]
["low freq, many artifacts","UPN_Tr2_057",2,25461999,"C","A","DNMT3A","ENST00000264709","missense_variant","aGg/aTg|p.Arg803Met/c.2408G>T",7172,77,7259,0.0106075216972035,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.186,"Deleterious",34.72,31.51,7172,77,7259,0.0106075216972035,0,0,0,"NA",1,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25462014,"A","G","DNMT3A","ENST00000264709","missense_variant","cTt/cCt|p.Leu798Pro/c.2393T>C",2349,25,2377,0.01051745898191,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.488,"Deleterious",33.94,33.88,2349,25,2377,0.01051745898191,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected","UPN_Tr2_103",2,25462016,"G","T","DNMT3A","ENST00000264709","missense_variant","aaC/aaA|p.Asn797Lys/c.2391C>A",4114,256,4379,0.0584608358072619,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.732,"Deleterious",34.9,34.91,4114,256,4379,0.0584608358072619,0,0,0,"NA",1,1,2,"Artifact (0)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",2,25462016,"GT","G","DNMT3A","ENST00000264709","frameshift_variant","aac/|p.Asn797fs/c.2390delA",1799,30,1858,0.0161463939720129,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",34.12,"NA",1799,30,1858,0.0161463939720129,0,0,0,"NA",1,1,2,"Artifact (2)"]
["Not in 2nd Illumina, bad alignment, many artifacts","UPN_Tr2_006",2,25462039,"T","A","DNMT3A","ENST00000264709","missense_variant","Agg/Tgg|p.Arg790Trp/c.2368A>T",2068,29,2105,0.0137767220902613,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.643,"Deleterious",32.62,28.14,2068,29,2105,0.0137767220902613,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low bq, low freq, many artifacts","UPN_Tr2_077",2,25462045,"C","T","DNMT3A","ENST00000264709","missense_variant","Gca/Aca|p.Ala788Thr/c.2362G>A",2545,33,2601,0.0126874279123414,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.255,"Deleterious",30.25,24.18,1304,15,1321,0.0113550340651022,1241,18,1280,0.0140625,0.599996049008676,1,1,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_065",2,25462053,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val785Glu/c.2354T>A",2211,25,2314,0.0108038029386344,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.132,"Deleterious",26.71,25.08,1093,9,1170,0.00769230769230769,1118,16,1144,0.013986013986014,0.228103868010554,2,2,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_086",2,25462053,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val785Glu/c.2354T>A",815,20,855,0.0233918128654971,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.132,"Deleterious",26.46,23.45,408,9,435,0.0206896551724138,407,11,420,0.0261904761904762,0.821658048725409,2,2,"Artifact (1)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_068",2,25462057,"C","T","DNMT3A","ENST00000264709","missense_variant","Gaa/Aaa|p.Glu784Lys/c.2350G>A",1713,24,1742,0.0137772675086108,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4768020","biliary_tract",1,"NO","NO","NO","NO","NO","NO",-0.571,"Tolerated",32.2,30.96,863,12,876,0.0136986301369863,850,12,866,0.0138568129330254,1,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_090",2,25462060,"T","C","DNMT3A","ENST00000264709","missense_variant","Aaa/Gaa|p.Lys783Glu/c.2347A>G",6836,83,6944,0.0119527649769585,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.661,"Tolerated",33.82,31.55,3431,41,3487,0.0117579581301979,3405,42,3457,0.0121492623662135,0.912411611006691,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_099",2,25462068,"A","G","DNMT3A","ENST00000264709","missense_variant","aTt/aCt|p.Ile780Thr/c.2339T>C",4820,67,4921,0.0136151188782768,0,0,0,0,1,1,0,1,3,0.0116,"NO","COSM1583121","haematopoietic_and_lymphoid_tissue",2,"NO","rs370751539","NO","NO","NO","NO",-4.232,"Deleterious",29.88,33.04,2422,34,2470,0.0137651821862348,2398,33,2451,0.0134638922888617,1,1,1,"Artifact (1)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_048",2,25462074,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val778Glu/c.2333T>A",10637,213,10941,0.0194680559363861,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.896,"Deleterious",28.39,25.07,5415,66,5526,0.011943539630836,5222,147,5415,0.0271468144044321,6.4273443131579E-009,2,2,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_093",2,25462074,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val778Glu/c.2333T>A",4010,44,4086,0.0107684777288302,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.896,"Deleterious",30.88,30.8,2012,19,2048,0.00927734375,1998,25,2038,0.0122669283611384,0.367816420377758,2,2,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25463178,"A","G","DNMT3A","ENST00000264709","missense_variant","tTt/tCt|p.Phe772Ser/c.2315T>C",3495,42,3540,0.011864406779661,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.862,"Deleterious",35.23,34.76,3495,42,3540,0.011864406779661,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected","UPN_Tr2_053",2,25463182,"G","A","DNMT3A","ENST00000264709","stop_gained","Cga/Tga|p.Arg771*/c.2311C>T",16876,208,17117,0.0121516620903196,0,0,0,0,1,0,0,1,2,"NO","NO","COSM231563","haematopoietic_and_lymphoid_tissue",5,"NO","NO","NO","NO","NO","NO","NA","NA",35.09,35.41,16851,208,17092,0.0121694359934472,25,0,25,0,1,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25463196,"T","C","DNMT3A","ENST00000264709","missense_variant","aAg/aGg|p.Lys766Arg/c.2297A>G",3476,55,3540,0.0155367231638418,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",35.08,34.53,3476,55,3540,0.0155367231638418,0,0,0,"NA",1,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25463214,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","gcc/|p.Ala760fs/c.2278delG",3429,36,3539,0.0101723650748799,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35,"NA",3429,36,3539,0.0101723650748799,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_044",2,25463215,"C","T","DNMT3A","ENST00000264709","missense_variant","Gcc/Acc|p.Ala760Thr/c.2278G>A",3429,55,3539,0.0155411133088443,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.78,"Deleterious",35,34.29,3429,55,3539,0.0155411133088443,0,0,0,"NA",1,1,1,"Artifact (3)"]
["inspected, low freq, no database","UPN_Tr2_075",2,25463242,"AG","A","DNMT3A","ENST00000264709","frameshift_variant","ccc/|p.Phe751fs/c.2250delC",24015,337,24435,0.0137916922447309,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.98,"NA",12109,173,12327,0.0140342337957329,11906,164,12108,0.0135447637925339,0.742435796341844,1,1,"Artifact (2)"]
["inspected","UPN_Tr2_111",2,25463248,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg749Cys/c.2245C>T",20554,418,21012,0.0198933942509042,0,0,0,0,1,1,0,1,3,"NO","NO","COSM219133","haematopoietic_and_lymphoid_tissue, skin","4, 1","NO","NO","NO","NA","NO","NO",-7.695,"Deleterious",33.57,34.13,10327,211,10543,0.0200132789528597,10227,207,10469,0.0197726621453816,0.960602743896953,1,1,"Artifact (1)"]
["inspected, low freq","UPN_Tr2_106",2,25463289,"T","C","DNMT3A","ENST00000264709","missense_variant","tAc/tGc|p.Tyr735Cys/c.2204A>G",22557,336,22932,0.0146520146520147,0,0,0,0,1,1,0,1,3,0.0116,"NO","COSM133126","haematopoietic_and_lymphoid_tissue",5,"NO","rs147828672","NO","NA","NO","NO",-6.941,"Deleterious",32.71,31.77,11287,166,11482,0.0144574116007664,11270,170,11450,0.0148471615720524,0.826206052358283,2,2,"Artifact (1)"]
["inspected, low freq","UPN_Tr2_101",2,25463307,"CG","C","DNMT3A","ENST00000264709","frameshift_variant","cgg/|p.Arg729fs/c.2185delC",8272,101,8406,0.0120152272186533,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.91,"NA",0,0,0,"NA",8272,101,8406,0.0120152272186533,1,1,2,"Artifact (3)"]
["Not in 2nd Illumina, bad alignment, many artifacts","UPN_Tr2_006",2,25463527,"C","T","DNMT3A","ENST00000264709","missense_variant","Gct/Act|p.Ala719Thr/c.2155G>A",4079,44,4124,0.0106692531522793,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.916,"Deleterious",33.82,34.95,1512,3,1515,0.00198019801980198,2567,41,2609,0.0157148332694519,2,1,1,"Artifact (2)"]
["Not in 2nd Illumina, bad alignment, many artifacts","UPN_Tr2_006",2,25463553,"C","T","DNMT3A","ENST00000264709","missense_variant","tGc/tAc|p.Cys710Tyr/c.2129G>A",4071,47,4125,0.0113939393939394,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-10.887,"Deleterious",35.47,34.81,1470,44,1515,0.029042904290429,2601,3,2610,0.00114942528735632,2.23102676300908E-016,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_044",2,25463560,"T","TG","DNMT3A","ENST00000264709","frameshift_variant","ggc/ggcC|p.Ser708fs/c.2121dupC",2919,44,2930,0.0150170648464164,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.4,"NA",717,0,722,0,2202,44,2208,0.0199275362318841,2,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_044",2,25463561,"G","GC","DNMT3A","ENST00000264709","frameshift_variant","ggc/ggGc|p.Ser708fs/c.2120dupG",2925,51,2930,0.0174061433447099,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.47,"NA",721,1,722,0.00138504155124654,2204,50,2208,0.0226449275362319,2,1,1,"Artifact (3)"]
["Not in 2nd Illumina, bad alignment, many artifacts","UPN_Tr2_006",2,25463578,"C","T","DNMT3A","ENST00000264709","missense_variant","Gat/Aat|p.Asp702Asn/c.2104G>A",1510,31,1542,0.0201037613488975,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-4.949,"Deleterious",35.46,32.39,1509,3,1513,0.00198281559814937,1,28,29,0.96551724137931,2.79983342601494E-055,1,1,"Artifact (0)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_080",2,25463583,"G","A","DNMT3A","ENST00000264709","missense_variant","cCa/cTa|p.Pro700Leu/c.2099C>T",10052,145,10228,0.0141767696519359,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-9.897,"Deleterious",34.66,35.53,10052,145,10228,0.0141767696519359,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_042",2,25463590,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgg/Cgg|p.Trp698Arg/c.2092T>C",7272,103,7424,0.0138739224137931,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-12.123,"Deleterious",31.01,34.5,7272,103,7424,0.0138739224137931,0,0,0,"NA",1,2,2,"Artifact (2)"]
["Not in 2nd Illumina, bad alignment, many artifacts","UPN_Tr2_006",2,25463590,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgg/Cgg|p.Trp698Arg/c.2092T>C",1457,41,1513,0.0270984798413748,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-12.123,"Deleterious",30.36,35.61,1457,41,1513,0.0270984798413748,0,0,0,"NA",1,2,2,"Artifact (0)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25464462,"A","G","DNMT3A","ENST00000264709","missense_variant","gTc/gCc|p.Val684Ala/c.2051T>C",2315,25,2362,0.010584250635055,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.787,"Deleterious",25.63,34.64,2315,25,2362,0.010584250635055,0,0,0,"NA",1,1,1,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_004",2,25464489,"A","G","DNMT3A","ENST00000264709","missense_variant","gTg/gCg|p.Val675Ala/c.2024T>C",2032,23,2062,0.0111542192046557,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.19,"Deleterious",25.24,30.78,1022,13,1037,0.0125361620057859,1010,10,1025,0.00975609756097561,0.676092163006514,1,2,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25464489,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val675Glu/c.2024T>A",4703,68,4787,0.0142051389179027,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.02,"Deleterious",25.68,26.38,2373,29,2410,0.0120331950207469,2330,39,2377,0.0164072360117796,0.222610952920088,1,2,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts","UPN_Tr2_054",2,25464498,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val672Glu/c.2015T>A",11570,138,11826,0.0116692034500254,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.803,"Deleterious",25.95,21.49,5878,26,5970,0.00435510887772194,5692,112,5856,0.0191256830601093,1.34826918432995E-014,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_019",2,25464537,"C","T","DNMT3A","ENST00000264709","missense_variant","cGc/cAc|p.Arg659His/c.1976G>A",9687,145,9843,0.0147312811134817,0,0,0,0,1,1,0,1,3,"NO","NO","COSM1019235","central_nervous_system, endometrium","1, 1","NO","NO","NO",1.647E-005,"NO","NO",-2.681,"Deleterious",33.69,31.26,4867,73,4944,0.0147653721682848,4820,72,4899,0.0146968769136558,1,2,2,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25464537,"C","T","DNMT3A","ENST00000264709","missense_variant","cGc/cAc|p.Arg659His/c.1976G>A",4719,68,4791,0.0141932790649134,0,0,0,0,1,0,0,1,2,"NO","NO","COSM1019235","central_nervous_system, endometrium","1, 1","NO","NO","NO",1.647E-005,"NO","NO",-2.681,"Deleterious",34.54,29.04,2373,34,2409,0.0141137401411374,2346,34,2382,0.0142737195633921,1,2,2,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25464549,"A","G","DNMT3A","ENST00000264709","missense_variant","aTt/aCt|p.Ile655Thr/c.1964T>C",2346,29,2390,0.0121338912133891,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.046,"Deleterious",31.88,35.34,8,0,8,0,2338,29,2382,0.0121746431570109,1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_093",2,25464561,"T","C","DNMT3A","ENST00000264709","missense_variant","aAg/aGg|p.Lys651Arg/c.1952A>G",2648,32,2680,0.0119402985074627,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.516,"Tolerated",34.61,35.59,0,0,0,"NA",2648,32,2680,0.0119402985074627,1,1,1,"Artifact (3)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25466769,"G","T","DNMT3A","ENST00000264709","missense_variant","aCa/aAa|p.Thr645Lys/c.1934C>A",2223,31,2257,0.0137350465219318,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.588,"Deleterious",34.98,34.19,2223,31,2257,0.0137350465219318,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_048",2,25466785,"A","G","DNMT3A","ENST00000264709","missense_variant","Ttt/Ctt|p.Phe640Leu/c.1918T>C",14150,148,14316,0.0103380832634814,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.502,"Deleterious",35.48,35.23,14150,148,14316,0.0103380832634814,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_048",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",13926,159,14186,0.0112082334696179,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",22.56,25.43,13926,159,14186,0.0112082334696179,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_059",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",6161,290,6492,0.0446703635243376,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.39,15.28,6161,290,6492,0.0446703635243376,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_091",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4010,42,4071,0.0103168754605748,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.26,17.14,4010,42,4071,0.0103168754605748,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_061",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3818,181,4045,0.0447466007416564,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.73,15.77,3818,181,4045,0.0447466007416564,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_062",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",2936,149,3111,0.0478945676631308,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.82,15.15,2936,149,3111,0.0478945676631308,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_063",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3789,156,3966,0.0393343419062027,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.23,16.04,3789,156,3966,0.0393343419062027,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_065",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5014,210,5253,0.0399771559109081,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.46,15.31,5014,210,5253,0.0399771559109081,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_066",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4638,182,4852,0.0375103050288541,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.06,15.65,4638,182,4852,0.0375103050288541,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_068",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3837,190,4065,0.046740467404674,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.76,15.2,3837,190,4065,0.046740467404674,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_070",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3070,141,3239,0.0435319543068848,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.21,15.03,3070,141,3239,0.0435319543068848,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_071",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",2977,128,3126,0.0409468969929623,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.86,15.75,2977,128,3126,0.0409468969929623,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_073",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4027,167,4225,0.0395266272189349,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.44,15.13,4027,167,4225,0.0395266272189349,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_074",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3026,121,3175,0.0381102362204724,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.59,15.63,3026,121,3175,0.0381102362204724,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_075",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5116,223,5377,0.0414729403012832,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.28,15.07,5116,223,5377,0.0414729403012832,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_077",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4699,244,4976,0.0490353697749196,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.94,15.56,4699,244,4976,0.0490353697749196,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_078",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4141,169,4344,0.0389042357274401,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.04,15.35,4141,169,4344,0.0389042357274401,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_080",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4039,178,4244,0.0419415645617342,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.72,15.44,4039,178,4244,0.0419415645617342,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_081",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",6887,350,7289,0.048017560707916,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.02,15.14,6887,350,7289,0.048017560707916,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_082",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5106,181,5324,0.0339969947407964,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.93,15.08,5106,181,5324,0.0339969947407964,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_084",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4983,227,5233,0.0433785591438945,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.11,15.06,4983,227,5233,0.0433785591438945,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_087",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",6382,332,6749,0.0491924729589569,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",19.8,15.28,6382,332,6749,0.0491924729589569,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_088",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4239,173,4435,0.0390078917700113,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",20.07,16.21,4239,173,4435,0.0390078917700113,0,0,0,"NA",1,31,31,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_095",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4171,45,4233,0.0106307583274274,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",22.9,20.02,4171,45,4233,0.0106307583274274,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_097",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5013,51,5084,0.0100314712824548,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.35,19.16,5010,51,5081,0.0100373942137375,3,0,3,0,1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_098",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3948,45,4005,0.0112359550561798,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",22.79,18.87,3948,45,4005,0.0112359550561798,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_102",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3788,47,3853,0.0121982870490527,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.43,17.96,3788,47,3853,0.0121982870490527,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_103",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",3135,35,3185,0.010989010989011,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",22.94,18.91,3135,35,3185,0.010989010989011,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_106",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",6333,65,6422,0.0101214574898785,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.13,18.45,6331,65,6420,0.0101246105919003,2,0,2,0,1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_109",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5339,55,5412,0.0101626016260163,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.11,19.56,5339,55,5412,0.0101626016260163,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_110",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",5431,63,5509,0.01143583227446,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.83,19.87,5431,63,5509,0.01143583227446,0,0,0,"NA",1,31,31,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts","UPN_Tr2_111",2,25466838,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val622Gly/c.1865T>G",4539,53,4604,0.011511728931364,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.825,"Deleterious",23.08,16.42,4539,53,4604,0.011511728931364,0,0,0,"NA",1,31,31,"Artifact (5)"]
["inspected, many artifacts","UPN_Tr2_072",2,25467047,"C","T","DNMT3A","ENST00000264709","missense_variant","Gct/Act|p.Ala610Thr/c.1828G>A",2902,35,2946,0.0118805159538357,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.485,"Tolerated",33.65,33.74,2902,35,2946,0.0118805159538357,0,0,0,"NA",1,1,1,"Artifact (4)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25467082,"C","A","DNMT3A","ENST00000264709","missense_variant","cGa/cTa|p.Arg598Leu/c.1793G>T",3315,47,3369,0.0139507272187593,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.486,"Deleterious",33.43,32.66,3299,47,3353,0.0140172979421414,16,0,16,0,1,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_053",2,25467099,"G","T","DNMT3A","ENST00000264709","stop_gained","taC/taA|p.Tyr592*/c.1776C>A",20468,289,20928,0.013809250764526,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",30.82,28.65,10063,130,10333,0.0125810510016452,10405,159,10595,0.0150070788107598,0.172903594093512,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25467118,"C","A","DNMT3A","ENST00000264709","missense_variant","tGc/tTc|p.Cys586Phe/c.1757G>T",2581,30,2619,0.011454753722795,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.795,"Deleterious",33.51,31.17,0,0,0,"NA",2581,30,2619,0.011454753722795,1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_058",2,25467121,"AT","A","DNMT3A","ENST00000264709","frameshift_variant","atg/|p.Met585fs/c.1754delA",7990,107,8149,0.0131304454534299,0,0,1,1,1,0,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.01,"NA",0,0,0,"NA",7990,107,8149,0.0131304454534299,1,1,1,"Artifact (1)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25467154,"G","A","DNMT3A","ENST00000264709","missense_variant","gCa/gTa|p.Ala574Val/c.1721C>T",3365,42,3411,0.0123131046613896,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.654,"Tolerated",34.98,34.4,0,0,0,"NA",3365,42,3411,0.0123131046613896,1,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_014",2,25467198,"G","T","DNMT3A","ENST00000264709","stop_gained","tgC/tgA|p.Cys559*/c.1677C>A",6886,80,6985,0.0114531138153185,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.51,35.08,0,0,0,"NA",6886,80,6985,0.0114531138153185,1,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_006",2,25467199,"CA","C","DNMT3A","ENST00000264709","frameshift_variant","ttt/|p.Cys559fs/c.1674delT",3361,42,3414,0.0123022847100176,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.49,"NA",0,0,0,"NA",3361,42,3414,0.0123022847100176,1,1,1,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25467202,"A","G","DNMT3A","ENST00000264709","missense_variant","tTt/tCt|p.Phe558Ser/c.1673T>C",2583,31,2625,0.0118095238095238,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.387,"Deleterious",34.99,34.77,0,0,0,"NA",2583,31,2625,0.0118095238095238,1,1,1,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25467409,"C","A","DNMT3A","ENST00000264709","missense_variant","aGg/aTg|p.Arg556Met/c.1667G>T",2931,61,2993,0.0203808887403943,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.382,"Deleterious",35.06,32.75,2930,61,2992,0.0203877005347594,1,0,1,0,1,1,1,"Artifact (0)"]
["inspected, low freq","UPN_Tr2_022",2,25467410,"TGCAGCAGTTGTTGTTTCCGCACATGA","T","DNMT3A","ENST00000264709","frameshift_variant","ctcatgtgcggaaacaacaactgctgc/|p.Leu547fs/c.1640_1665delTCATGTGCGGAAACAACAACTGCTGC",4667,61,4735,0.012882787750792,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.96,"NA",4667,61,4735,0.012882787750792,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",2,25467416,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgc/Cgc|p.Cys554Arg/c.1660T>C",2218,24,2246,0.0106856634016028,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-10.765,"Deleterious",35.27,35.83,2218,24,2246,0.0106856634016028,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_056",2,25467433,"A","G","DNMT3A","ENST00000264709","missense_variant","aTg/aCg|p.Met548Thr/c.1643T>C",4421,59,4488,0.0131461675579323,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.322,"Deleterious",34.8,34.24,4421,59,4488,0.0131461675579323,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",2,25467437,"G","A","DNMT3A","ENST00000264709","missense_variant","Ctc/Ttc|p.Leu547Phe/c.1639C>T",2204,29,2245,0.0129175946547884,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-2.122,"Tolerated",34.13,28.59,2204,29,2245,0.0129175946547884,0,0,0,"NA",1,2,2,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25467437,"G","A","DNMT3A","ENST00000264709","missense_variant","Ctc/Ttc|p.Leu547Phe/c.1639C>T",2733,57,2805,0.0203208556149733,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-2.122,"Tolerated",33.97,30.79,2733,57,2805,0.0203208556149733,0,0,0,"NA",1,2,2,"Artifact (0)"]
["inspected, many artifacts","UPN_Tr2_057",2,25467447,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly543fs/c.1628delG",6830,77,6931,0.0111095080075025,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.86,"NA",6830,77,6931,0.0111095080075025,0,0,0,"NA",1,2,2,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_092",2,25467447,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly543fs/c.1628delG",2663,33,2700,0.0122222222222222,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.14,"NA",2663,33,2700,0.0122222222222222,0,0,0,"NA",1,2,2,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25467452,"C","A","DNMT3A","ENST00000264709","missense_variant","Ggg/Tgg|p.Gly542Trp/c.1624G>T",2764,36,2803,0.0128433820906172,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.635,"Deleterious",34.72,32.58,2764,36,2803,0.0128433820906172,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25467458,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgc/Cgc|p.Cys540Arg/c.1618T>C",2760,32,2800,0.0114285714285714,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-10.709,"Deleterious",34.69,32.47,2760,32,2800,0.0114285714285714,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected","UPN_Tr2_046",2,25468133,"G","A","DNMT3A","ENST00000264709","stop_gained","Caa/Taa|p.Gln515*/c.1543C>T",10211,348,10622,0.0327621916776502,0,0,0,0,1,0,0,1,2,"NO","NO","COSM1318927","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",34.87,35.4,10211,348,10622,0.0327621916776502,0,0,0,"NA",1,1,1,"Artifact (0)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25468184,"C","T","DNMT3A","ENST00000264709","missense_variant","Ggg/Agg|p.Gly498Arg/c.1492G>A",2600,45,2647,0.017000377786173,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.722,"Deleterious",34.36,32.87,2600,45,2647,0.017000377786173,0,0,0,"NA",1,1,1,"Artifact (2)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25468196,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgc/Cgc|p.Cys494Arg/c.1480T>C",5073,58,5190,0.0111753371868979,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.759,"Deleterious",31.85,32.97,2593,30,2628,0.0114155251141553,2480,28,2562,0.0109289617486339,1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25468895,"T","A","DNMT3A","ENST00000264709","missense_variant","Att/Ttt|p.Ile490Phe/c.1468A>T",1353,31,1389,0.0223182145428366,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.41,"Tolerated",35.59,34.58,1353,31,1389,0.0223182145428366,0,0,0,"NA",1,1,1,"Artifact (1)"]
["not in 2nd Illumina, low freq, no database","UPN_Tr2_006",2,25468924,"A","G","DNMT3A","ENST00000264709","missense_variant","gTg/gCg|p.Val480Ala/c.1439T>C",2050,38,2115,0.0179669030732861,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.912,"Tolerated",32.74,35.68,2050,38,2115,0.0179669030732861,0,0,0,"NA",1,1,2,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_006",2,25468924,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val480Glu/c.1439T>A",2050,27,2115,0.0127659574468085,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.753,"Tolerated",32.74,36,2050,27,2115,0.0127659574468085,0,0,0,"NA",1,1,2,"Artifact (3)"]
["inspected, many artifacts, low freq","UPN_Tr2_048",2,25468931,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgg/Tgg|p.Arg478Trp/c.1432C>T",9365,97,9470,0.0102428722280887,0,0,0,0,1,0,0,1,2,"NO","NO","COSM87003","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NA","NO","NO",-3.948,"Deleterious",34.58,33.08,9353,97,9458,0.0102558680482132,12,0,12,0,1,1,1,"Artifact (1)"]
["low freq, many artifacts, many samples","UPN_Tr2_014",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",11964,218,12208,0.0178571428571429,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33,31.17,7500,215,7733,0.0278029225397646,4464,3,4475,0.000670391061452514,8.55609932559687E-039,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_015",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",16009,171,16223,0.0105405905196326,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.97,31.13,10073,168,10276,0.0163487738419619,5936,3,5947,0.000504456028249538,1.99560373228383E-029,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_016",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7865,96,7980,0.0120300751879699,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.05,30.69,4829,92,4933,0.0186499087776201,3036,4,3047,0.00131276665572694,4.58329448381367E-015,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_017",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",5361,103,5470,0.0188299817184643,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.78,30.91,3597,99,3700,0.0267567567567568,1764,4,1770,0.00225988700564972,9.58106318927496E-013,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_018",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",8602,119,8746,0.0136062199862794,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.02,31.14,5316,115,5449,0.0211047898697009,3286,4,3297,0.00121322414316045,4.05062264162941E-019,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_019",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",8874,139,9036,0.0153829127932714,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.04,31.32,5406,138,5562,0.0248112189859763,3468,1,3474,0.000287852619458837,2.77247988033426E-028,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_020",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7902,140,8058,0.0173740382228841,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.88,30.96,5179,140,5332,0.0262565641410353,2723,0,2726,0,4.58398090725833E-026,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_021",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9387,159,9559,0.0166335390731248,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.04,31.46,5665,159,5834,0.027254028111073,3722,0,3725,0,6.10285652430022E-035,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_002",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7545,109,7663,0.0142241941798251,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.29,30.97,3846,107,3959,0.027027027027027,3699,2,3704,0.000539956803455724,1.45877229462578E-028,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_003",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",1550,25,1576,0.0158629441624365,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.44,30.12,717,23,741,0.0310391363022942,833,2,835,0.00239520958083832,2.31901504034437E-006,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_022",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",10913,122,11054,0.0110367287859598,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.97,31.38,6759,120,6892,0.0174114915844457,4154,2,4162,0.000480538202787122,2.27898398049717E-022,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_023",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",12803,160,12989,0.0123181153283548,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.01,31.2,7797,156,7975,0.0195611285266458,5006,4,5014,0.000797766254487435,4.18705445161542E-028,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_024",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",5760,66,5841,0.0112994350282486,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.95,30.64,3660,62,3733,0.0166086257701581,2100,4,2108,0.00189753320683112,1.61652695251636E-008,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_025",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",15259,198,15489,0.0127832655432888,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.08,31.11,9106,190,9321,0.0203840789614848,6153,8,6168,0.0012970168612192,3.83675373269013E-032,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_026",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",14280,203,14519,0.0139816791790068,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.99,31.02,8916,198,9145,0.0216511755057408,5364,5,5374,0.000930405656866394,2.88773792160167E-033,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_027",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",14580,242,14860,0.0162853297442799,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.16,31.31,8561,237,8830,0.0268403171007928,6019,5,6030,0.000829187396351575,9.48710411239543E-047,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_028",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",10309,139,10466,0.0132811007070514,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.21,31.48,6118,136,6270,0.0216905901116427,4191,3,4196,0.000714966634890372,1.42402412317907E-026,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_044",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",3729,39,3773,0.0103366021733369,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.63,29.87,2370,37,2409,0.0153590701535907,1359,2,1364,0.00146627565982405,1.18150693789429E-005,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_029",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",13009,190,13222,0.0143699894115867,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.92,31.33,8477,187,8680,0.0215437788018433,4532,3,4542,0.000660501981505945,2.06614425556413E-030,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_030",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",12898,198,13133,0.015076524784893,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.98,31.49,8198,194,8418,0.0230458541221193,4700,4,4715,0.000848356309650053,2.20857301066776E-032,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_031",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9563,115,9702,0.0118532261389404,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.01,31.77,5883,114,6014,0.0189557698703026,3680,1,3688,0.00027114967462039,6.8385343711042E-023,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_005",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",2528,51,2583,0.0197444831591173,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.3,32,1278,51,1332,0.0382882882882883,1250,0,1251,0,1.34094208825074E-015,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_032",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",4379,51,4438,0.0114916629112213,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.02,30.51,2717,47,2769,0.0169736366919466,1662,4,1669,0.00239664469742361,1.58426701753564E-006,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_033",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9689,112,9835,0.0113879003558719,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.11,31.12,5762,112,5894,0.0190023752969121,3927,0,3941,0,9.3873895248994E-026,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_034",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",3784,51,3843,0.0132708821233411,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.03,30.73,2416,49,2473,0.0198139911039224,1368,2,1370,0.00145985401459854,7.45931337836556E-008,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_035",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",12550,193,12772,0.0151111807077983,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.08,30.78,7559,184,7761,0.0237082850148177,4991,9,5011,0.00179604869287567,1.77224485962214E-029,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_036",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",17190,303,17520,0.0172945205479452,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.98,31.02,10831,298,11148,0.0267312522425547,6359,5,6372,0.000784682988072819,1.17293546398933E-051,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_006",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",3847,74,3926,0.0188487009679063,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.49,31.12,1782,74,1858,0.0398277717976319,2065,0,2068,0,4.20653190023201E-025,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_037",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",21203,308,21567,0.0142810775722168,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.99,31.53,13484,305,13834,0.0220471302587827,7719,3,7733,0.000387947756368809,1.15662745766789E-054,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_038",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",21671,333,22049,0.0151027257471994,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.02,31.2,13459,329,13822,0.0238026334828534,8212,4,8227,0.000486203962562295,4.67922672566504E-061,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_039",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",18352,305,18701,0.0163092882733544,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.09,31.3,11078,303,11415,0.0265440210249671,7274,2,7286,0.000274499039253363,1.56324835511599E-062,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_007",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",15989,228,16259,0.0140230026446891,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.36,30.85,7893,218,8136,0.0267944936086529,8096,10,8123,0.00123107226394189,1.08379707219993E-052,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_008",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",24262,391,24714,0.0158209921501983,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.05,31.13,13849,385,14279,0.0269626724560543,10413,6,10435,0.000574988021082894,5.97681815511775E-083,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_009",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",19624,231,19908,0.0116033755274262,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.02,31.62,11469,230,11735,0.0195994887089902,8155,1,8173,0.000122354092744402,8.82879226205003E-052,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_010",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",12908,173,13128,0.0131779402803169,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.51,30.72,5887,171,6083,0.0281111293769522,7021,2,7045,0.00028388928317956,8.19224731741933E-055,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_011",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",13173,201,13393,0.0150078399163742,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.48,30.55,5937,194,6141,0.0315909460999837,7236,7,7252,0.000965250965250965,1.32866488702012E-056,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_058",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",17343,183,17597,0.0103994999147582,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.83,30.37,10273,173,10488,0.0164950419527079,7070,10,7109,0.00140666760444507,1.71914479998561E-027,51,51,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_012",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",8354,133,8516,0.0156176608736496,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.41,31.38,3978,131,4118,0.0318115590092278,4376,2,4398,0.00045475216007276,6.62863571507489E-039,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_040",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7636,132,7787,0.0169513291383074,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",32.98,31.37,4963,128,5105,0.0250734573947111,2673,4,2682,0.00149142431021626,5.29436671671679E-019,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_013",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",4677,63,4757,0.0132436409501787,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.38,31.65,2307,62,2381,0.0260394792104158,2370,1,2376,0.000420875420875421,4.64375484389921E-018,51,51,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_062",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9970,120,10104,0.0118764845605701,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.85,30.92,3466,119,3593,0.0331199554689674,6504,1,6511,0.000153586238673015,7.24595128050039E-053,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_063",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7939,89,8054,0.0110504097342935,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",34.19,30.99,2051,84,2154,0.0389972144846797,5888,5,5900,0.000847457627118644,1.35356273815673E-042,51,51,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_071",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9305,169,9487,0.0178138505323074,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.46,30.3,4187,162,4358,0.0371730151445617,5118,7,5129,0.00136478845778904,5.67124644644402E-046,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_072",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",10373,120,10509,0.0114187838995147,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.82,29.66,3723,108,3840,0.028125,6650,12,6669,0.00179937022042285,1.13379149799992E-034,51,51,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_075",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",11007,123,11174,0.01100769643816,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.87,30.8,3779,117,3912,0.0299079754601227,7228,6,7262,0.000826218672541999,5.11210526781774E-046,51,51,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_076",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7167,84,7264,0.0115638766519824,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.98,30.02,2324,77,2408,0.0319767441860465,4843,7,4856,0.00144151565074135,1.46126680712118E-029,51,51,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_078",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9164,110,9287,0.0118445138365457,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.8,30.97,3398,106,3508,0.0302166476624857,5766,4,5779,0.000692161273576743,5.30618931094326E-040,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_080",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9446,117,9583,0.0122091203172284,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",34.06,29.85,2833,107,2946,0.0363204344874406,6613,10,6637,0.00150670483652253,1.04834798293568E-043,51,51,"Artifact (4)"]
["inspected, strandbias, bad alignment","UPN_Tr2_081",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",13244,159,13417,0.0118506372512484,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.78,30.28,4757,148,4912,0.0301302931596091,8487,11,8505,0.0012933568489124,1.32933626199833E-051,51,51,"Artifact (4)"]
["inspected, strandbias, bad alignment","UPN_Tr2_083",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",9149,110,9272,0.0118636755823986,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",33.98,30.62,2657,106,2772,0.0382395382395382,6492,4,6500,0.000615384615384615,7.56541272951457E-051,51,51,"Artifact (5)"]
["inspected, strandbias, bad alignment","UPN_Tr2_084",2,25469031,"C","G","DNMT3A","ENST00000264709","missense_variant","aGa/aCa|p.Arg476Thr/c.1427G>C",7629,86,7738,0.0111139829413285,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.331,"Deleterious",34.09,30.94,2192,83,2278,0.0364354697102722,5437,3,5460,0.000549450549450549,1.23117858822025E-040,51,51,"Artifact (5)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",2,25469076,"G","A","DNMT3A","ENST00000264709","missense_variant","aCa/aTa|p.Thr461Ile/c.1382C>T",3767,40,3814,0.010487676979549,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.531,"Tolerated",34.83,34.8,2438,7,2451,0.00285597715218278,1329,33,1363,0.0242112986060161,2,1,2,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_006",2,25469076,"GT","G","DNMT3A","ENST00000264709","frameshift_variant","aca/|p.Thr461fs/c.1381delA",3870,40,3919,0.0102066853789232,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.22,"NA",1857,0,1861,0,2013,40,2058,0.0194363459669582,2,1,2,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_001",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5439,637,6089,0.104614879290524,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.62,31.62,3189,9,3206,0.00280723643169058,2250,628,2883,0.217828650711065,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_014",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11512,714,12259,0.0582429235663594,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.99,31.52,7797,13,7829,0.00166049303870226,3715,701,4430,0.15823927765237,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_015",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",15477,757,16281,0.0464959154843069,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.99,31.91,10322,29,10381,0.00279356516713226,5155,728,5900,0.123389830508475,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_016",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7501,470,7986,0.0588529927372903,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.93,31.76,4952,11,4976,0.00221061093247588,2549,459,3010,0.152491694352159,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_017",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5205,267,5491,0.0486250227645238,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.14,31.64,3717,7,3734,0.00187466523835029,1488,260,1757,0.147979510529311,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_018",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8244,495,8761,0.0565003994977742,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.97,31.72,5468,12,5493,0.00218459858001092,2776,483,3268,0.147796817625459,2,111,111,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_019",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8478,559,9059,0.0617065901313611,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.95,31.79,5600,13,5628,0.00230987917555082,2878,546,3431,0.159137277761586,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_020",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7659,404,8085,0.0499690785405071,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.12,31.77,5353,10,5379,0.00185908161368284,2306,394,2706,0.14560236511456,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_021",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8945,600,9588,0.0625782227784731,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.88,31.87,5838,21,5893,0.00356354997454607,3107,579,3695,0.156698240866035,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_002",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6847,804,7675,0.104755700325733,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.64,31.67,3988,5,4007,0.00124781632143748,2859,799,3668,0.21782988004362,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_003",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",1385,187,1577,0.11857958148383,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.56,31.54,748,3,755,0.00397350993377483,637,184,822,0.223844282238443,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_022",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",10437,607,11082,0.0547735065872586,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.95,31.69,6915,23,6962,0.00330364837690319,3522,584,4120,0.141747572815534,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_023",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12253,742,13036,0.0569193003988954,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.93,31.77,8008,21,8061,0.0026051358392259,4245,721,4975,0.144924623115578,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_041",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",13822,806,14664,0.0549645390070922,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.29,31.38,2573,5,2592,0.00192901234567901,11249,801,12072,0.066351888667992,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_024",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5535,308,5856,0.0525956284153005,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.98,31.69,3735,16,3763,0.00425192665426521,1800,292,2093,0.139512661251792,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_025",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",14546,980,15573,0.0629294291401785,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.92,31.77,9398,21,9451,0.00222198709131309,5148,959,6122,0.156648154197975,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_026",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",13743,779,14558,0.053510097540871,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.97,31.88,9207,19,9247,0.00205472044987564,4536,760,5311,0.143099228017323,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_004",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",876,234,1111,0.210621062106211,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.12,31.69,97,0,97,0,779,234,1014,0.230769230769231,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_027",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",13830,1005,14876,0.0675584834632966,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.9,31.47,8881,21,8927,0.00235241402486838,4949,984,5949,0.165405950579929,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_089",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9448,237,9703,0.0244254354323405,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.94,31.95,5630,21,5662,0.00370893677145885,3818,216,4041,0.0534521158129176,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_042",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",23627,827,24556,0.0336781234728783,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.54,31.73,15180,43,15300,0.00281045751633987,8447,784,9256,0.0847018150388937,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_028",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9818,627,10470,0.0598853868194842,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.92,31.85,6277,29,6327,0.00458353089932037,3541,598,4143,0.144339850349988,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_043",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",14385,426,14864,0.0286598493003229,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.7,31.39,9732,25,9802,0.00255049989798,4653,401,5062,0.079217700513631,2,111,111,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_044",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3656,144,3815,0.0377457404980341,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.63,31.97,2430,11,2452,0.00448613376835237,1226,133,1363,0.0975788701393984,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_029",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12503,718,13267,0.0541192432350946,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.07,31.75,8694,22,8752,0.00251371115173675,3809,696,4515,0.154152823920266,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_030",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12424,707,13179,0.0536459518931634,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.04,31.82,8450,23,8502,0.00270524582451188,3974,684,4677,0.146247594611931,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_031",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9174,532,9736,0.0546425636811832,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.91,31.77,6060,15,6088,0.00246386333771353,3114,517,3648,0.14172149122807,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_005",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",2304,270,2583,0.104529616724739,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.69,31.6,1333,1,1338,0.000747384155455904,971,269,1245,0.216064257028112,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_045",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",21285,423,21797,0.0194063403220627,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.75,31.69,15116,38,15231,0.00249491169325717,6169,385,6566,0.05863539445629,2,111,111,"Artifact (8)"]
["bad alignment, strandbias, many samples","UPN_Tr2_032",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4185,236,4441,0.0531411844179239,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.84,31.82,2767,4,2787,0.00143523501973448,1418,232,1654,0.140266021765417,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_046",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",18053,808,18928,0.0426880811496196,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.58,31.81,11932,53,12040,0.00440199335548173,6121,755,6888,0.109610917537747,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_033",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9264,561,9858,0.0569080949482654,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.88,31.68,5908,14,5943,0.00235571260306243,3356,547,3915,0.139719029374202,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_034",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3649,186,3854,0.0482615464452517,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.07,31.62,2472,7,2494,0.00280673616680032,1177,179,1360,0.131617647058824,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_047",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",28027,975,29144,0.0334545704090036,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.63,31.57,18576,67,18749,0.0035735239212758,9451,908,10395,0.0873496873496873,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_048",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16260,898,17267,0.0520067180170267,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.08,31.55,7937,16,7981,0.00200476130810675,8323,882,9286,0.0949816928709886,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_035",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11990,763,12807,0.0595767939408136,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.97,31.78,7799,15,7847,0.00191155855741048,4191,748,4960,0.150806451612903,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_036",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16574,995,17618,0.056476331025088,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.99,31.59,11232,31,11295,0.00274457724656928,5342,964,6323,0.152459275660288,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_006",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3436,466,3912,0.119120654396728,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.49,31.78,1848,3,1860,0.00161290322580645,1588,463,2052,0.225633528265107,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_049",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",19240,625,19980,0.0312812812812813,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.59,31.79,12639,39,12782,0.00305116570176811,6601,586,7198,0.081411503195332,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_050",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",19335,364,19789,0.0183940573045631,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.68,31.77,13412,52,13537,0.00384132377927163,5923,312,6252,0.0499040307101727,2,111,111,"Artifact (8)"]
["bad alignment, strandbias, many samples","UPN_Tr2_037",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",20464,1083,21622,0.0500878734622144,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.02,31.69,13863,32,13954,0.00229324924752759,6601,1051,7668,0.137063119457486,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_051",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",15733,489,16296,0.0300073637702504,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.58,31.37,10116,35,10209,0.00342834753648741,5617,454,6087,0.0745851815344176,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_052",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16786,396,17236,0.0229751682524948,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.61,31.87,11157,44,11251,0.00391076348768998,5629,352,5985,0.0588137009189641,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_038",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",20833,1229,22129,0.0555379818337928,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.98,31.75,13870,29,13947,0.00207930020793002,6963,1200,8182,0.146663407479834,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_039",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",17593,1078,18724,0.0575731681264687,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.96,31.89,11459,29,11524,0.00251648733078792,6134,1049,7200,0.145694444444444,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_053",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",20610,776,21495,0.036101418934636,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.58,31.89,13566,55,13706,0.00401284109149278,7044,721,7789,0.092566439851072,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_054",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12335,370,12761,0.0289945929002429,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.47,31.77,7692,29,7770,0.00373230373230373,4643,341,4991,0.0683229813664596,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_007",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",14559,1668,16268,0.102532579296779,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.55,31.61,8180,19,8223,0.00231059224127447,6379,1649,8045,0.20497203231821,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_008",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",22601,2106,24786,0.0849673202614379,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.73,31.69,14348,32,14436,0.00221668052091992,8253,2074,10350,0.200386473429952,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_009",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",18462,1429,19944,0.0716506217408744,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.78,31.58,11805,24,11865,0.00202275600505689,6657,1405,8079,0.173907661839337,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_010",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11668,1385,13095,0.105765559373807,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.36,31.61,6084,23,6134,0.00374959243560483,5584,1362,6961,0.19566154288177,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_011",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11945,1439,13416,0.107259988073942,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.42,31.72,6172,15,6209,0.00241584796263489,5773,1424,7207,0.197585680588317,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_055",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",21854,674,22616,0.0298019101521047,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.65,31.82,14932,43,15044,0.00285828237170965,6922,631,7572,0.0833333333333333,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_056",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9792,343,10173,0.0337167010714637,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.56,31.83,6164,39,6234,0.00625601539942252,3628,304,3939,0.0771769484640772,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_090",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8778,207,8999,0.0230025558395377,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.77,32.26,5036,21,5063,0.00414773849496346,3742,186,3936,0.0472560975609756,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_057",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16780,703,17568,0.0400159380692168,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.51,31.78,10825,28,10917,0.00256480718146011,5955,675,6651,0.10148849797023,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_058",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16773,814,17654,0.0461085306446131,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.54,31.64,10540,17,10605,0.0016030174446016,6233,797,7049,0.113065683075614,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_059",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4799,770,5587,0.137819939144442,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.19,31.54,722,1,725,0.00137931034482759,4077,769,4862,0.158165364047717,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_012",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7665,829,8522,0.0972776343581319,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.44,31.73,4118,12,4151,0.00289086966995905,3547,817,4371,0.186913749714024,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_060",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7192,1085,8293,0.130833232846979,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.68,31.75,2359,7,2374,0.0029486099410278,4833,1078,5919,0.182125359013347,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_040",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7382,385,7797,0.0493779658843145,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.03,31.78,5110,16,5147,0.00310860695550806,2272,369,2650,0.139245283018868,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_013",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4246,501,4761,0.105229993698803,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.52,31.62,2388,6,2408,0.00249169435215947,1858,495,2353,0.210369740756481,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_091",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8289,229,8532,0.026840131270511,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",34.04,31.92,5077,17,5102,0.00333202665621325,3212,212,3430,0.0618075801749271,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_092",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5041,115,5162,0.022278186749322,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.92,31.67,3042,4,3049,0.00131190554280092,1999,111,2113,0.0525319451017511,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_093",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6261,164,6432,0.0254975124378109,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.82,32.12,3637,16,3658,0.00437397484964461,2624,148,2774,0.053352559480894,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_061",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",7675,1170,8875,0.131830985915493,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.57,31.64,2432,4,2442,0.00163800163800164,5243,1166,6433,0.181252914658791,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_062",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8849,1223,10102,0.12106513561671,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.91,31.67,3592,10,3615,0.00276625172890733,5257,1213,6487,0.186989363342069,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_063",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6906,1076,7998,0.134533633408352,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.68,31.61,2160,1,2163,0.000462320850670365,4746,1075,5835,0.184233076263925,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_064",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6096,1216,7333,0.16582571935088,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.21,31.69,1046,1,1048,0.000954198473282443,5050,1215,6285,0.193317422434368,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_065",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3975,642,4620,0.138961038961039,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.26,31.49,763,2,765,0.00261437908496732,3212,640,3855,0.166018158236057,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_066",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",2741,513,3264,0.157169117647059,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",31.92,31.64,213,0,215,0,2528,513,3049,0.168251885864218,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_067",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",2992,539,3541,0.152216887884778,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.09,31.56,409,1,410,0.0024390243902439,2583,538,3131,0.17183008623443,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_068",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4453,715,5179,0.13805754006565,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.35,31.56,902,0,903,0,3551,715,4276,0.167212347988775,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_069",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6986,1019,8023,0.127009846690764,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.49,31.64,1769,3,1776,0.00168918918918919,5217,1016,6247,0.16263806627181,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_070",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3988,615,4616,0.133232235701906,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.46,31.52,974,2,980,0.00204081632653061,3014,613,3636,0.168591859185919,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_071",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8517,944,9487,0.0995045852218826,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.3,31.46,4369,6,4391,0.00136643133682532,4148,938,5096,0.184065934065934,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_072",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9210,1210,10467,0.115601413967708,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.01,31.52,3866,14,3897,0.00359250705671029,5344,1196,6570,0.182039573820396,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_073",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5748,842,6600,0.127575757575758,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.65,31.59,1652,5,1659,0.00301386377335744,4096,837,4941,0.169398907103825,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_074",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",2941,469,3416,0.137295081967213,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.31,31.7,699,1,702,0.00142450142450142,2242,468,2714,0.17243920412675,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_075",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9927,1172,11128,0.105319913731129,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.96,31.58,3920,9,3939,0.00228484386900229,6007,1163,7189,0.161774933926833,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_076",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6453,772,7243,0.106585668921718,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.83,31.52,2405,5,2419,0.0020669698222406,4048,767,4824,0.158996683250415,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_077",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5333,878,6220,0.141157556270096,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.4,31.57,1124,7,1132,0.00618374558303887,4209,871,5088,0.171187106918239,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_078",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8248,1014,9282,0.109243697478992,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.08,31.63,3520,7,3533,0.00198131899235777,4728,1007,5749,0.1751608975474,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_079",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4680,590,5293,0.111467976572832,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.71,31.55,1583,4,1594,0.00250941028858218,3097,586,3699,0.158421194917545,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_080",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8341,1164,9525,0.122204724409449,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.84,31.57,2959,4,2970,0.00134680134680135,5382,1160,6555,0.176964149504195,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_081",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12134,1256,13422,0.0935777082402027,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.94,31.67,4918,13,4949,0.00262679329157406,7216,1243,8473,0.146701286439278,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_082",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4526,622,5160,0.120542635658915,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.39,31.68,1100,7,1109,0.00631199278629396,3426,615,4051,0.151814366823007,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_083",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8083,1151,9261,0.124284634488716,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.77,31.43,2796,10,2815,0.00355239786856128,5287,1141,6446,0.17700899782811,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_084",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6879,805,7704,0.104491173416407,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.74,31.52,2274,12,2293,0.00523331879633668,4605,793,5411,0.146553317316577,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_085",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",3632,466,4107,0.113464816167519,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.61,31.74,1051,4,1059,0.00377714825306893,2581,462,3048,0.151574803149606,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_086",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",1970,240,2210,0.108597285067873,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.49,31.55,554,0,554,0,1416,240,1656,0.144927536231884,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_087",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",6175,877,7068,0.124080362195812,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.45,31.68,1566,6,1578,0.00380228136882129,4609,871,5490,0.158652094717669,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_088",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",4421,713,5153,0.138366000388123,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",32.47,31.67,1132,3,1140,0.00263157894736842,3289,710,4013,0.176924993770247,2,111,111,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_094",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11969,306,12292,0.0248942401561992,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.86,31.77,7023,20,7050,0.00283687943262411,4946,286,5242,0.0545593285005723,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_095",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",10001,267,10283,0.0259651852572207,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.79,31.89,5791,10,5809,0.00172146668961956,4210,257,4474,0.0574430040232454,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_096",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11005,228,11248,0.0202702702702703,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.93,32.05,6682,22,6712,0.0032777115613826,4323,206,4536,0.0454144620811287,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_097",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",13436,364,13818,0.0263424518743668,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.99,31.63,8290,9,8309,0.0010831628354796,5146,355,5509,0.0644400072608459,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_098",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",9501,225,9739,0.0231029879864462,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.94,31.5,5773,9,5791,0.00155413572785357,3728,216,3948,0.0547112462006079,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_099",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",5125,134,5266,0.0254462590201291,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.96,32.25,3154,11,3167,0.00347331859804231,1971,123,2099,0.0585993330157218,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_100",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8462,227,8699,0.0260949534429245,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.82,31.81,4732,14,4755,0.00294426919032597,3730,213,3944,0.0540060851926978,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_101",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8744,198,8950,0.022122905027933,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.71,31.77,4834,4,4846,0.000825423029302518,3910,194,4104,0.047270955165692,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_102",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8875,237,9130,0.0259583789704272,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.81,31.8,5076,13,5098,0.0025500196155355,3799,224,4032,0.0555555555555556,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_103",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",8873,240,9133,0.0262783313259608,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.79,31.69,5103,8,5125,0.0015609756097561,3770,232,4008,0.0578842315369262,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_104",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11359,291,11663,0.0249506987910486,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.93,31.67,6931,8,6950,0.00115107913669065,4428,283,4713,0.0600466793974114,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_105",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",10227,254,10499,0.0241927802647871,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.83,31.78,6052,9,6071,0.00148245758524131,4175,245,4428,0.0553297199638663,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_106",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",15303,310,15633,0.0198298471182754,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.81,31.83,8935,20,8970,0.00222965440356745,6368,290,6663,0.0435239381659913,2,111,111,"Artifact (8)"]
["bad alignment, strandbias, many samples","UPN_Tr2_107",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",16338,349,16713,0.0208819481840483,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.93,31.72,10133,18,10167,0.00177043375627029,6205,331,6546,0.0505652306752215,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_108",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12917,267,13200,0.0202272727272727,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.83,31.47,7313,7,7333,0.000954588844947498,5604,260,5867,0.0443156638827339,2,111,111,"Artifact (6)"]
["bad alignment, strandbias, many samples","UPN_Tr2_109",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",12868,235,13129,0.0178993068779039,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.88,31.7,7511,16,7537,0.00212286055459732,5357,219,5592,0.0391630901287554,2,111,111,"Artifact (8)"]
["bad alignment, strandbias, many samples","UPN_Tr2_110",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",14096,211,14329,0.0147253820922605,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.84,31.86,8355,20,8391,0.0023835061375283,5741,191,5938,0.0321657123610643,2,111,111,"Artifact (8)"]
["bad alignment, strandbias, many samples","UPN_Tr2_111",2,25469083,"T","C","DNMT3A","ENST00000264709","missense_variant","Aag/Gag|p.Lys459Glu/c.1375A>G",11214,258,11489,0.022456262511968,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.273,"Tolerated",33.94,31.62,6776,20,6807,0.00293815190245336,4438,238,4682,0.0508329773601025,2,111,111,"Artifact (6)"]
["inspected, many artifacts","UPN_Tr2_006",2,25469086,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgg/Tgg|p.Arg458Trp/c.1372C>T",1829,22,1860,0.0118279569892473,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.888,"Deleterious",35,33.82,1829,22,1860,0.0118279569892473,0,0,0,"NA",1,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_041",2,25469088,"G","A","DNMT3A","ENST00000264709","missense_variant","cCc/cTc|p.Pro457Leu/c.1370C>T",2551,33,2593,0.0127265715387582,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.644,"Tolerated",34.06,32.42,2550,33,2592,0.0127314814814815,1,0,1,0,1,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_041",2,25469102,"TG","T","DNMT3A","ENST00000264709","frameshift_variant","cca/|p.Pro452fs/c.1355delC",2550,26,2588,0.0100463678516229,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.03,"NA",2550,26,2588,0.0100463678516229,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_006",2,25469121,"G","A","DNMT3A","ENST00000264709","missense_variant","gCt/gTt|p.Ala446Val/c.1337C>T",1820,36,1859,0.0193652501344809,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.798,"Tolerated",34.77,31.33,1820,36,1859,0.0193652501344809,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_085",2,25469154,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val435Glu/c.1304T>A",2078,27,2119,0.0127418593676262,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.143,"Tolerated",30.93,24.11,1041,7,1056,0.00662878787878788,1037,20,1063,0.0188146754468485,0.018437284411458,1,1,"Artifact (5)"]
["inspected, many artifacts","UPN_Tr2_006",2,25469166,"G","A","DNMT3A","ENST00000264709","missense_variant","cCc/cTc|p.Pro431Leu/c.1292C>T",3634,78,3723,0.0209508460918614,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.738,"Tolerated",33.07,34.44,1807,38,1852,0.0205183585313175,1827,40,1871,0.0213789417423838,0.909112464724638,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469171,"C","G","DNMT3A","ENST00000264709","missense_variant","aaG/aaC|p.Lys429Asn/c.1287G>C",4849,54,4913,0.0109912477101567,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.585,"Tolerated",33.33,31.63,2397,26,2429,0.0107039934129271,2452,28,2484,0.0112721417069243,0.891723207424505,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469174,"C","A","DNMT3A","ENST00000264709","missense_variant","gaG/gaT|p.Glu428Asp/c.1284G>T",4848,53,4911,0.010792099368764,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.96,"Tolerated",32.51,30.11,2395,28,2427,0.011536876802637,2453,25,2484,0.0100644122383253,0.679459423857353,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469176,"C","T","DNMT3A","ENST00000264709","missense_variant","Gag/Aag|p.Glu428Lys/c.1282G>A",4838,58,4909,0.0118150336117336,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.14,"Tolerated",33.16,32.12,2391,29,2425,0.0119587628865979,2447,29,2484,0.0116747181964573,1,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_062",2,25469516,"C","T","DNMT3A","ENST00000264709","missense_variant","Ggc/Agc|p.Gly418Ser/c.1252G>A",1931,29,1960,0.0147959183673469,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.805,"Deleterious",35.35,35.24,1931,29,1960,0.0147959183673469,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_006",2,25469519,"A","G","DNMT3A","ENST00000264709","missense_variant","Tct/Cct|p.Ser417Pro/c.1249T>C",1669,23,1701,0.0135214579659024,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.71,"Tolerated",29.44,34.3,1669,23,1701,0.0135214579659024,0,0,0,"NA",1,1,1,"Artifact (3)"]
["inspected, many samples, homopolymer 6C, ins and del","UPN_Tr2_036",2,25469529,"G","GC","DNMT3A","ENST00000264709","frameshift_variant","ggc/ggGc|p.Phe414fs/c.1238dupG",7265,144,7272,0.0198019801980198,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.44,"NA",7265,144,7272,0.0198019801980198,0,0,0,"NA",1,3,75,"Artifact (5)"]
["inspected, many samples, homopolymer 6C, ins and del","UPN_Tr2_039",2,25469529,"G","GC","DNMT3A","ENST00000264709","frameshift_variant","ggc/ggGc|p.Phe414fs/c.1238dupG",6847,131,6855,0.0191101385849745,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.41,"NA",6847,131,6855,0.0191101385849745,0,0,0,"NA",1,3,75,"Artifact (5)"]
["inspected, many samples, homopolymer 6C, ins and del","UPN_Tr2_040",2,25469529,"G","GC","DNMT3A","ENST00000264709","frameshift_variant","ggc/ggGc|p.Phe414fs/c.1238dupG",3055,63,3063,0.0205680705190989,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.56,"NA",3055,63,3063,0.0205680705190989,0,0,0,"NA",1,3,75,"Artifact (3)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_001",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2192,25,2221,0.0112561909049977,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.46,"NA",2192,25,2221,0.0112561909049977,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_014",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4401,55,4469,0.012307003803983,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.45,"NA",4401,55,4469,0.012307003803983,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_015",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6250,83,6354,0.0130626377085301,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.48,"NA",6250,83,6354,0.0130626377085301,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_016",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2744,36,2787,0.0129171151776103,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.53,"NA",2744,36,2787,0.0129171151776103,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_018",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2996,36,3036,0.0118577075098814,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.47,"NA",2996,36,3036,0.0118577075098814,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_020",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2988,48,3041,0.0157842814863532,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.53,"NA",2988,48,3041,0.0157842814863532,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_021",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3439,42,3497,0.0120102945381756,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.49,"NA",3439,42,3497,0.0120102945381756,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_002",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2963,34,3000,0.0113333333333333,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.39,"NA",2963,34,3000,0.0113333333333333,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_022",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4160,44,4209,0.0104537894986933,0,0,0,1,0,0,0,1,2,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.43,"NA",4160,44,4209,0.0104537894986933,0,0,0,"NA",1,72,75,"Artifact (8)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_023",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5024,72,5109,0.0140927774515561,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.49,"NA",5022,72,5107,0.0140982964558449,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_041",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",13388,152,13591,0.0111838716797881,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.08,"NA",13388,152,13591,0.0111838716797881,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_024",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2123,33,2163,0.0152565880721221,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.46,"NA",2123,33,2163,0.0152565880721221,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_025",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5165,61,5233,0.0116567934263329,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.4,"NA",5164,61,5232,0.0116590214067278,1,0,1,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_026",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5202,66,5277,0.0125071063104036,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.46,"NA",5202,66,5277,0.0125071063104036,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_027",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5902,75,5996,0.0125083388925951,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.44,"NA",5900,75,5994,0.0125125125125125,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_089",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3631,50,3686,0.0135648399348888,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.39,"NA",3631,50,3686,0.0135648399348888,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_042",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",7432,107,7576,0.0141235480464625,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.1,"NA",7432,107,7576,0.0141235480464625,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_043",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4902,77,5003,0.0153907655406756,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.15,"NA",4900,77,5001,0.0153969206158768,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_044",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",1869,25,1903,0.0131371518654756,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.05,"NA",1869,25,1903,0.0131371518654756,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_029",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5444,60,5515,0.0108794197642792,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.39,"NA",5443,60,5514,0.0108813928182807,1,0,1,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_030",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4595,57,4660,0.0122317596566524,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.49,"NA",4587,57,4652,0.0122527944969905,8,0,8,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_031",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2966,37,3007,0.0123046225473894,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.49,"NA",2966,37,3007,0.0123046225473894,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_045",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6717,98,6834,0.0143400643839625,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.11,"NA",6717,98,6834,0.0143400643839625,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_032",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",1813,33,1854,0.0177993527508091,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.51,"NA",1813,33,1854,0.0177993527508091,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_046",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6701,84,6806,0.0123420511313547,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.17,"NA",6701,84,6806,0.0123420511313547,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_033",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3612,40,3657,0.0109379272627837,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.45,"NA",3610,40,3655,0.0109439124487004,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_047",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",9561,118,9706,0.0121574283948073,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.22,"NA",9561,118,9706,0.0121574283948073,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_048",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",10413,135,10613,0.0127202487515311,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.14,"NA",10413,135,10613,0.0127202487515311,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_035",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4675,53,4738,0.0111861544955678,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.49,"NA",4675,53,4738,0.0111861544955678,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_036",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",7169,90,7272,0.0123762376237624,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.42,"NA",7169,90,7272,0.0123762376237624,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_049",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",7092,103,7213,0.0142797726327464,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.1,"NA",7079,103,7200,0.0143055555555556,13,0,13,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_050",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6090,74,6187,0.0119605624696945,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.14,"NA",6090,74,6187,0.0119605624696945,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_037",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",8002,97,8121,0.0119443418298239,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.4,"NA",8002,97,8121,0.0119443418298239,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_051",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5026,73,5118,0.0142633841344275,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.19,"NA",5026,73,5118,0.0142633841344275,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_052",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6157,103,6278,0.0164064988849952,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.22,"NA",6157,103,6278,0.0164064988849952,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_038",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",8057,106,8177,0.0129631894337777,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.41,"NA",8057,106,8177,0.0129631894337777,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_039",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6740,89,6855,0.012983223924143,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.4,"NA",6740,89,6855,0.012983223924143,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_053",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6768,110,6912,0.0159143518518519,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.18,"NA",6768,110,6912,0.0159143518518519,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_054",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4918,81,5018,0.016141889198884,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.15,"NA",4918,81,5018,0.016141889198884,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_011",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4626,58,4692,0.0123614663256607,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.41,"NA",4626,58,4692,0.0123614663256607,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_055",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",7213,97,7332,0.0132296781232951,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.11,"NA",7213,97,7332,0.0132296781232951,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_056",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4248,52,4322,0.012031466913466,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.04,"NA",4248,52,4322,0.012031466913466,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_090",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3383,41,3433,0.0119429070783571,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.32,"NA",3383,41,3433,0.0119429070783571,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_057",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",6094,70,6180,0.0113268608414239,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.06,"NA",6094,70,6180,0.0113268608414239,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_058",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",7002,113,7140,0.0158263305322129,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.05,"NA",7002,113,7140,0.0158263305322129,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_012",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2994,32,3035,0.0105436573311367,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.5,"NA",2994,32,3035,0.0105436573311367,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_040",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3019,37,3063,0.0120796604635978,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.44,"NA",3019,37,3063,0.0120796604635978,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_013",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",1599,26,1628,0.015970515970516,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.48,"NA",1599,26,1628,0.015970515970516,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_091",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3323,49,3377,0.0145099200473793,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.41,"NA",3323,49,3377,0.0145099200473793,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_092",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2395,33,2436,0.0135467980295567,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.32,"NA",2395,33,2436,0.0135467980295567,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_062",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",1929,20,1960,0.0102040816326531,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.29,"NA",1929,20,1960,0.0102040816326531,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_071",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2668,44,2720,0.0161764705882353,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.17,"NA",2668,44,2720,0.0161764705882353,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_072",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2450,29,2482,0.0116841257050766,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.19,"NA",2450,29,2482,0.0116841257050766,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_075",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",1829,26,1860,0.0139784946236559,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.32,"NA",1829,26,1860,0.0139784946236559,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_080",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",2029,27,2058,0.0131195335276968,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.17,"NA",2029,27,2058,0.0131195335276968,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_081",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3065,34,3108,0.0109395109395109,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.26,"NA",3065,34,3108,0.0109395109395109,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_094",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3916,45,3967,0.011343584572725,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.38,"NA",3916,45,3967,0.011343584572725,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_095",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4167,58,4228,0.0137180700094607,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.36,"NA",4155,58,4216,0.0137571157495256,12,0,12,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_096",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3801,55,3861,0.0142450142450142,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.42,"NA",3801,55,3861,0.0142450142450142,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_097",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4645,61,4714,0.0129401781926177,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.31,"NA",4645,61,4714,0.0129401781926177,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_098",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3903,47,3955,0.0118836915297092,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.41,"NA",3903,47,3955,0.0118836915297092,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_100",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3021,38,3066,0.0123939986953686,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.39,"NA",3017,38,3062,0.0124101894186806,4,0,4,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_101",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3949,46,4006,0.0114827758362456,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.43,"NA",3949,46,4006,0.0114827758362456,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_102",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3818,45,3870,0.0116279069767442,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.37,"NA",3818,45,3870,0.0116279069767442,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_103",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3293,34,3333,0.0102010201020102,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.42,"NA",3291,34,3331,0.0102071450015011,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_104",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4016,50,4075,0.0122699386503067,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.41,"NA",4014,50,4073,0.0122759636631476,2,0,2,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_105",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",3384,38,3428,0.0110851808634772,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.39,"NA",3381,38,3425,0.0110948905109489,3,0,3,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_106",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4589,57,4653,0.0122501611863314,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.3,"NA",4589,57,4653,0.0122501611863314,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_107",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5957,71,6030,0.0117744610281924,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.36,"NA",5957,71,6030,0.0117744610281924,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_108",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",5169,60,5239,0.0114525672838328,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.36,"NA",5169,60,5239,0.0114525672838328,0,0,0,"NA",1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_109",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4686,50,4742,0.0105440742302826,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.27,"NA",4683,50,4739,0.0105507491031863,3,0,3,0,1,72,75,"Artifact (6)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_111",2,25469529,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggc/|p.Gly413fs/c.1238delG",4543,53,4602,0.0115167318557149,0,0,0,1,1,0,0,1,3,0.1457,"NO","NO","NA","NA","NO","NO","NO",4.119E-005,"NO","NO","NA","NA",35.33,"NA",4543,53,4602,0.0115167318557149,0,0,0,"NA",1,72,75,"Artifact (6)"]
["inspected, many artifacts","UPN_Tr2_108",2,25469542,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp409*/c.1226G>A",5163,66,5234,0.0126098586167367,0,0,0,0,1,0,0,1,2,"NO","NO","COSM3991222","kidney",1,"NO","NO","NO","NO","NO","NO","NA","NA",34.34,34.18,5163,66,5234,0.0126098586167367,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low bq, bad alignment, many samples","UPN_Tr2_060",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",934,36,980,0.036734693877551,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",19.86,15.61,934,36,980,0.036734693877551,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_061",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",1533,89,1635,0.054434250764526,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",19.76,15.01,1533,89,1635,0.054434250764526,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_063",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",1317,55,1384,0.0397398843930636,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",20.18,15.09,1317,55,1384,0.0397398843930636,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_065",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",546,25,572,0.0437062937062937,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",19.82,15.24,546,25,572,0.0437062937062937,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_077",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",933,35,976,0.0358606557377049,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",20.18,15.2,933,35,976,0.0358606557377049,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_079",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",759,34,793,0.042875157629256,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.034,"Tolerated",19.51,15.38,759,34,793,0.042875157629256,0,0,0,"NA",1,6,7,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_041",2,25469566,"A","G","DNMT3A","ENST00000264709","missense_variant","gTg/gCg|p.Val401Ala/c.1202T>C",13031,134,13385,0.0100112065745237,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.602,"Tolerated",21.28,32.59,13031,134,13385,0.0100112065745237,0,0,0,"NA",1,1,7,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_079",2,25469585,"T","C","DNMT3A","ENST00000264709","missense_variant","Act/Gct|p.Thr395Ala/c.1183A>G",1540,20,1572,0.0127226463104326,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.209,"Tolerated",30.46,31.6,778,10,792,0.0126262626262626,762,10,780,0.0128205128205128,1,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_056",2,25469588,"C","T","DNMT3A","ENST00000264709","missense_variant","Gac/Aac|p.Asp394Asn/c.1180G>A",8398,91,8503,0.0107021051393626,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4836021","cervix",1,"NO","NO","NO","NO","NO","NO",-0.813,"Tolerated",32.37,32.95,4199,45,4252,0.0105832549388523,4199,46,4251,0.0108209832980475,1,1,1,"Artifact (3)"]
["low bq, low freq, many artifacts","UPN_Tr2_041",2,25469589,"A","T","DNMT3A","ENST00000264709","missense_variant","agT/agA|p.Ser393Arg/c.1179T>A",26232,273,26822,0.0101782119155917,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.602,"Tolerated",28.13,23.83,13041,84,13363,0.00628601361969618,13191,189,13459,0.0140426480422022,3.47822220553857E-010,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469595,"A","T","DNMT3A","ENST00000264709","missense_variant","gaT/gaA|p.Asp391Glu/c.1173T>A",3629,67,3730,0.0179624664879357,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.052,"Tolerated",30.19,27.81,1821,26,1864,0.0139484978540773,1808,41,1866,0.0219721329046088,0.08359483618258,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469604,"G","T","DNMT3A","ENST00000264709","missense_variant","caC/caA|p.His388Gln/c.1164C>A",3674,49,3727,0.0131473034612289,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.158,"Tolerated",32.56,29.82,1834,25,1861,0.0134336378291241,1840,24,1866,0.0128617363344051,0.886845289604277,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_078",2,25469618,"A","G","DNMT3A","ENST00000264709","missense_variant","Ttc/Ctc|p.Phe384Leu/c.1150T>C",2624,32,2697,0.0118650352243233,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.277,"Deleterious",30.24,34.75,737,14,782,0.0179028132992327,1887,18,1915,0.00939947780678851,0.0728575410299681,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_078",2,25469633,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg379Cys/c.1135C>T",1892,24,1917,0.0125195618153365,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO",2.471E-005,"NO","NO",-5.62,"Deleterious",34.52,33.79,0,0,0,"NA",1892,24,1917,0.0125195618153365,1,2,3,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469633,"G","T","DNMT3A","ENST00000264709","missense_variant","Cgc/Agc|p.Arg379Ser/c.1135C>A",1832,33,1870,0.0176470588235294,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.316,"Deleterious",34.94,31.48,0,0,0,"NA",1832,33,1870,0.0176470588235294,1,1,3,"Artifact (2)"]
["inspected","UPN_Tr2_041",2,25469922,"G","A","DNMT3A","ENST00000264709","stop_gained","Cag/Tag|p.Gln374*/c.1120C>T",615,32,647,0.0494590417310665,0,0,0,0,1,0,0,1,2,0,"NO","NO","NO","O","NO","rs369109129","NO",1.647E-005,"NO","NO","NA","NA",35.32,34.03,615,32,647,0.0494590417310665,0,0,0,"NA",1,1,1,"Artifact (0)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_072",2,25469927,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val372Gly/c.1115T>G",3476,46,3545,0.0129760225669958,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.765,"Tolerated",22.8,15.87,3476,46,3545,0.0129760225669958,0,0,0,"NA",1,2,4,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_083",2,25469927,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val372Gly/c.1115T>G",2050,25,2085,0.0119904076738609,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.765,"Tolerated",22.33,15.64,2042,25,2077,0.0120365912373616,8,0,8,0,1,2,4,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469927,"A","G","DNMT3A","ENST00000264709","missense_variant","gTc/gCc|p.Val372Ala/c.1115T>C",2306,32,2348,0.0136286201022147,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.237E-006,"NO","NO",0.59,"Tolerated",23.48,35.19,2306,32,2348,0.0136286201022147,0,0,0,"NA",1,1,4,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_048",2,25469963,"T","C","DNMT3A","ENST00000264709","missense_variant","aAc/aGc|p.Asn360Ser/c.1079A>G",2508,32,2554,0.0125293657008614,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.686,"Tolerated",33.15,34.59,2508,32,2554,0.0125293657008614,0,0,0,"NA",1,1,1,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_059",2,25469981,"A","C","DNMT3A","ENST00000264709","missense_variant","tTc/tGc|p.Phe354Cys/c.1061T>G",1381,84,1469,0.0571817562968005,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.358,"Deleterious",20.82,15.1,1363,84,1451,0.0578911095796003,18,0,18,0,0.619491187587434,2,2,"Artifact (2)"]
["low bq, bad alignment, many samples","UPN_Tr2_071",2,25469981,"A","C","DNMT3A","ENST00000264709","missense_variant","tTc/tGc|p.Phe354Cys/c.1061T>G",2483,121,2619,0.046200840015273,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.358,"Deleterious",20.54,15.12,2467,121,2603,0.0464848252016904,16,0,16,0,1,2,2,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_092",2,25469982,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttc/Gtc|p.Phe354Val/c.1060T>G",2088,23,2120,0.0108490566037736,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.639,"Deleterious",17.21,15.35,2088,23,2120,0.0108490566037736,0,0,0,"NA",1,2,4,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_093",2,25469982,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttc/Gtc|p.Phe354Val/c.1060T>G",2829,30,2884,0.0104022191400832,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.639,"Deleterious",17.42,15.17,2819,30,2873,0.0104420466411417,10,0,11,0,1,2,4,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts","UPN_Tr2_045",2,25469982,"A","G","DNMT3A","ENST00000264709","missense_variant","Ttc/Ctc|p.Phe354Leu/c.1060T>C",7483,81,7638,0.0106048703849175,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.876,"Deleterious",17.64,25.57,7483,81,7638,0.0106048703849175,0,0,0,"NA",1,2,4,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts","UPN_Tr2_069",2,25469982,"A","G","DNMT3A","ENST00000264709","missense_variant","Ttc/Ctc|p.Phe354Leu/c.1060T>C",2970,37,3187,0.0116096642610606,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.876,"Deleterious",16.28,23.3,2945,37,3162,0.0117014547754586,25,0,25,0,1,2,4,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_061",2,25469986,"A","C","DNMT3A","ENST00000264709","missense_variant","agT/agG|p.Ser352Arg/c.1056T>G",2517,137,2683,0.0510622437569884,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.028,"Tolerated",17.34,15.19,2476,137,2641,0.0518742900416509,41,0,42,0,0.270423308494781,2,2,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_065",2,25469986,"A","C","DNMT3A","ENST00000264709","missense_variant","agT/agG|p.Ser352Arg/c.1056T>G",976,43,1025,0.0419512195121951,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.028,"Tolerated",17.38,15.23,976,43,1025,0.0419512195121951,0,0,0,"NA",1,2,2,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_048",2,25469990,"C","T","DNMT3A","ENST00000264709","missense_variant","tGc/tAc|p.Cys351Tyr/c.1052G>A",2490,59,2550,0.0231372549019608,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO",-0.554,"Tolerated",33.56,31.49,2490,59,2550,0.0231372549019608,0,0,0,"NA",1,1,1,"Artifact (1)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_069",2,25469992,"A","C","DNMT3A","ENST00000264709","missense_variant","ttT/ttG|p.Phe350Leu/c.1050T>G",3136,38,3184,0.0119346733668342,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.721,"Deleterious",22.17,15.61,3111,38,3159,0.0120291231402343,25,0,25,0,1,2,2,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_084",2,25469992,"A","C","DNMT3A","ENST00000264709","missense_variant","ttT/ttG|p.Phe350Leu/c.1050T>G",2773,29,2814,0.0103056147832267,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.721,"Deleterious",21.92,15.38,2773,29,2814,0.0103056147832267,0,0,0,"NA",1,2,2,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_092",2,25469993,"A","C","DNMT3A","ENST00000264709","missense_variant","tTt/tGt|p.Phe350Cys/c.1049T>G",2091,22,2120,0.010377358490566,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.196,"Deleterious",21.23,18.82,2091,22,2120,0.010377358490566,0,0,0,"NA",1,3,3,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_066",2,25469993,"A","C","DNMT3A","ENST00000264709","missense_variant","tTt/tGt|p.Phe350Cys/c.1049T>G",756,40,803,0.049813200498132,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.196,"Deleterious",18.94,15.38,740,40,787,0.0508259212198221,16,0,16,0,1,3,3,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_095",2,25469993,"A","C","DNMT3A","ENST00000264709","missense_variant","tTt/tGt|p.Phe350Cys/c.1049T>G",4145,49,4212,0.011633428300095,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.196,"Deleterious",20.44,15.67,4145,49,4212,0.011633428300095,0,0,0,"NA",1,3,3,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_044",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",2261,53,2338,0.0226689478186484,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",20.15,31.49,2261,53,2338,0.0226689478186484,0,0,0,"NA",1,6,6,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_093",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",2828,38,2883,0.0131807145334721,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",19.01,15.24,2817,38,2872,0.0132311977715877,11,0,11,0,1,6,6,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_066",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",765,32,803,0.0398505603985056,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",17.57,15.09,749,32,787,0.0406607369758577,16,0,16,0,1,6,6,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_086",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",766,43,812,0.0529556650246305,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",17.45,15.6,756,43,802,0.0536159600997506,10,0,10,0,1,6,6,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_105",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",3847,40,3901,0.0102537810817739,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",18.97,15.65,3844,40,3898,0.0102616726526424,3,0,3,0,1,6,6,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts","UPN_Tr2_109",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",5229,54,5305,0.0101790763430726,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.317,"Deleterious",18.8,16.69,5225,54,5301,0.0101867572156197,4,0,4,0,1,6,6,"Artifact (5)"]
["low bq, low freq, tolerated prediction","UPN_Tr2_070",2,25469997,"A","C","DNMT3A","ENST00000264709","missense_variant","Tcg/Gcg|p.Ser349Ala/c.1045T>G",1440,136,1580,0.0860759493670886,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",21.38,15.21,1440,136,1580,0.0860759493670886,0,0,0,"NA",1,3,3,"Artifact (5)"]
["low bq, low freq, tolerated prediction","UPN_Tr2_072",2,25469997,"A","C","DNMT3A","ENST00000264709","missense_variant","Tcg/Gcg|p.Ser349Ala/c.1045T>G",3239,285,3531,0.08071367884452,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",21.67,15.22,3239,285,3531,0.08071367884452,0,0,0,"NA",1,3,3,"Artifact (5)"]
["low bq, low freq, tolerated prediction","UPN_Tr2_079",2,25469997,"A","C","DNMT3A","ENST00000264709","missense_variant","Tcg/Gcg|p.Ser349Ala/c.1045T>G",1751,127,1882,0.0674814027630181,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",21.96,15.3,1742,127,1873,0.0678056593699947,9,0,9,0,1,3,3,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_072",2,25470002,"A","C","DNMT3A","ENST00000264709","missense_variant","cTg/cGg|p.Leu347Arg/c.1040T>G",3406,101,3531,0.0286037949589351,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.688,"Deleterious",20.78,15.14,3406,101,3531,0.0286037949589351,0,0,0,"NA",1,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_048",2,25470008,"A","G","DNMT3A","ENST00000264709","missense_variant","aTg/aCg|p.Met345Thr/c.1034T>C",2507,36,2564,0.0140405616224649,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.257,"Tolerated",21.66,32.56,2490,36,2547,0.0141342756183746,17,0,17,0,1,1,1,"Artifact (5)"]
["low bq, low freq, many artifacts, many samples","UPN_Tr2_044",2,25470009,"T","G","DNMT3A","ENST00000264709","missense_variant","Atg/Ctg|p.Met345Leu/c.1033A>C",2419,31,2464,0.0125811688311688,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.238,"Tolerated",29.51,26.06,2295,30,2337,0.0128369704749679,124,1,127,0.0078740157480315,1,1,1,"Artifact (6)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_047",2,25470020,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val341Gly/c.1022T>G",19684,264,20206,0.0130654261110561,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.524,"Tolerated",21.94,15.09,9896,159,10178,0.015621929652191,9788,105,10028,0.0104706820901476,0.00153141163799427,1,1,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_020",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",5932,61,6044,0.0100926538716082,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",22.96,16.85,2968,36,3021,0.0119165839126117,2964,25,3023,0.00826993053258353,0.197818455303905,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_021",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",7509,97,7665,0.0126549249836921,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",23.05,16.44,3749,65,3837,0.016940317956737,3760,32,3828,0.00835945663531871,0.000979582636223577,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_030",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",9302,107,9481,0.0112857293534437,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",22.88,16.27,4641,76,4744,0.0160202360876897,4661,31,4737,0.00654422630356766,1.4474320378934E-005,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_032",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",3600,43,3672,0.0117102396514161,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",22.98,16.42,1793,30,1837,0.0163309744148067,1807,13,1835,0.00708446866485014,0.0131764573154731,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_033",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",7499,82,7641,0.0107315796361733,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",23.1,17.29,3735,63,3820,0.0164921465968586,3764,19,3821,0.00497252028264852,1.01248224985481E-006,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_035",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",9287,95,9470,0.0100316789862724,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",23.02,16.89,4630,74,4742,0.0156052298608182,4657,21,4728,0.00444162436548223,3.69650856268264E-008,8,8,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_039",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",15063,162,15337,0.0105626915302862,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",22.59,15.86,7511,111,7670,0.0144719687092568,7552,51,7667,0.00665188470066519,2.46660393521134E-006,8,8,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_110",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",9891,348,10296,0.0337995337995338,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.3,"Deleterious",23.62,17.01,4829,290,5144,0.0563763608087092,5062,58,5152,0.0112577639751553,1.20330759827453E-039,8,8,"Artifact (3)"]
["inspected, not in 2nd illumina, not in 454","UPN_Tr2_006",2,25470464,"G","T","DNMT3A","ENST00000264709","stop_gained","tCa/tAa|p.Ser337*/c.1010C>A",1274,59,1336,0.0441616766467066,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.7,34.22,1274,59,1336,0.0441616766467066,0,0,0,"NA",1,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_090",2,25470465,"A","G","DNMT3A","ENST00000264709","missense_variant","Tca/Cca|p.Ser337Pro/c.1009T>C",1872,24,1896,0.0126582278481013,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.022,"Deleterious",35.58,35.12,1855,24,1879,0.0127727514635444,17,0,17,0,1,1,1,"Artifact (3)"]
["inspected","UPN_Tr2_092",2,25470485,"CACATGACCCAGCGGGTGCCTTCAGCTGCTCGGCTCCGGCC","TACACGACGCTCTTCCGATCTGGCCACGGCTGGTGAAGAAGCCGCTCACCTCGTACTCTGGCT","DNMT3A","ENST00000264709","frameshift_variant+stop_gained","ggccggagccgagcagctgaaggcacccgctgggtcatgtgg/AGCCAGAGTACGAGGTGAGCGGCTTCTTCACCAGCCGTGGCCAGATCGGAAGAGCGTCGTGTAg|p.Gly317fs/c.949_989delGGCCGGAGCCGAGCAGCTGAAGGCACCCGCTGGGTCATGTGinsAGCCAGAGTACGAGGTGAGCGGCTTCTTCACCAGCCGTGGCCAGATCGGAAGAGCGTCGTGTA",1409,30,1422,0.0210970464135021,0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.6368292682927,"ComplexIndel","NA","NA","NA","NA","NA","NA","NA","NA","NA",1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_056",2,25470486,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgg/Cgg|p.Trp330Arg/c.988T>C",1504,25,1539,0.0162443144899285,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.751,"Deleterious",31.65,32.68,1500,25,1535,0.0162866449511401,4,0,4,0,1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_048",2,25470494,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp327*/c.980G>A",1689,38,1728,0.0219907407407407,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",31.59,32.53,1662,38,1701,0.0223398001175779,27,0,27,0,1,3,3,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_084",2,25470494,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp327*/c.980G>A",1292,33,1325,0.0249056603773585,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",30.37,31.55,1292,33,1325,0.0249056603773585,0,0,0,"NA",1,3,3,"Artifact (0)"]
["inspected, many artifacts","UPN_Tr2_097",2,25470498,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgc/Tgc|p.Arg326Cys/c.976C>T",3307,51,3377,0.0151021616819662,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4169721","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NA","NO","NO",-5.58,"Deleterious",31.53,31.25,3303,51,3373,0.015120071153276,4,0,4,0,1,2,2,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_056",2,25470501,"T","C","DNMT3A","ENST00000264709","missense_variant","Acc/Gcc|p.Thr325Ala/c.973A>G",1501,23,1529,0.0150425114453891,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.084,"Tolerated",34.54,35.09,1501,23,1529,0.0150425114453891,0,0,0,"NA",1,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_006",2,25470513,"C","T","DNMT3A","ENST00000264709","missense_variant","Gca/Aca|p.Ala321Thr/c.961G>A",2588,27,2618,0.0103132161955691,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.918,"Tolerated",34.22,31.81,1308,14,1322,0.010590015128593,1280,13,1296,0.0100308641975309,1,1,1,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_056",2,25470519,"T","C","DNMT3A","ENST00000264709","missense_variant","Agc/Ggc|p.Ser319Gly/c.955A>G",2967,38,3029,0.0125453945196434,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.976,"Tolerated",31.8,32.29,1499,18,1529,0.0117724002616089,1468,20,1500,0.0133333333333333,0.745772430828313,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_041",2,25470521,"C","A","DNMT3A","ENST00000264709","missense_variant","cGg/cTg|p.Arg318Leu/c.953G>T",308,22,332,0.0662650602409639,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.179,"Deleterious",31.56,32.68,196,11,208,0.0528846153846154,112,11,124,0.0887096774193548,0.253878991790296,1,2,"Artifact (0)"]
["low freq, many artifacts","UPN_Tr2_012",2,25470521,"C","T","DNMT3A","ENST00000264709","missense_variant","cGg/cAg|p.Arg318Gln/c.953G>A",4340,44,4392,0.0100182149362477,0,0,0,0,1,0,0,0,1,"NO","NO","COSM4312146","large_intestine, oesophagus","1, 1","NO","NO","NO","NO","NO","NO",-1.282,"Tolerated",33.38,32.02,2190,22,2214,0.00993676603432701,2150,22,2178,0.0101010101010101,1,1,2,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_071",2,25470524,"C","T","DNMT3A","ENST00000264709","missense_variant","gGc/gAc|p.Gly317Asp/c.950G>A",4065,43,4128,0.0104166666666667,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.26,"Tolerated",32.67,27.42,2056,21,2081,0.0100913022585296,2009,22,2047,0.0107474352711285,0.878742540938167,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_078",2,25470528,"T","A","DNMT3A","ENST00000264709","missense_variant","Acg/Tcg|p.Thr316Ser/c.946A>T",3677,46,3787,0.0121468180617903,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.018,"Tolerated",28.79,25.72,1878,28,1914,0.0146290491118077,1799,18,1873,0.00961025093432995,0.234880773795715,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_090",2,25470529,"C","T","DNMT3A","ENST00000264709","missense_variant","atG/atA|p.Met315Ile/c.945G>A",3620,53,3678,0.0144100054377379,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.424,"Tolerated",33.22,32.51,1822,27,1850,0.0145945945945946,1798,26,1828,0.0142231947483589,1,2,2,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_012",2,25470529,"C","T","DNMT3A","ENST00000264709","missense_variant","atG/atA|p.Met315Ile/c.945G>A",4313,62,4385,0.014139110604333,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.424,"Tolerated",33.73,32.97,2170,31,2207,0.0140462165835976,2143,31,2178,0.0142332415059688,1,2,2,"Artifact (4)"]
["inspected, many artifacts, low freq","UPN_Tr2_072",2,25470531,"TC","T","DNMT3A","ENST00000264709","frameshift_variant","tgg/|p.Trp314fs/c.942delG",3033,34,3082,0.0110317975340688,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.8,"NA",1534,17,1557,0.0109184328837508,1499,17,1525,0.0111475409836066,1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_067",2,25470532,"C","T","DNMT3A","ENST00000264709","stop_gained","tgG/tgA|p.Trp314*/c.942G>A",2444,32,2487,0.0128669079211902,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",32.8,33.03,1236,16,1258,0.0127186009538951,1208,16,1229,0.0130187144019528,1,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_006",2,25470536,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp313*/c.938G>A",2557,55,2619,0.0210003818251241,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.02,28.69,1292,27,1322,0.0204236006051437,1265,28,1297,0.0215882806476484,0.891943914751917,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_048",2,25470537,"A","G","DNMT3A","ENST00000264709","missense_variant","Tgg/Cgg|p.Trp313Arg/c.937T>C",3190,44,3257,0.013509364445809,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.051,"Deleterious",31.43,31.48,1634,23,1659,0.0138637733574442,1556,21,1598,0.0131414267834793,1,1,2,"Artifact (2)"]
["low bq, low freq, many artifacts","UPN_Tr2_046",2,25470537,"A","T","DNMT3A","ENST00000264709","missense_variant","Tgg/Agg|p.Trp313Arg/c.937T>A",12476,153,12687,0.012059588555214,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.051,"Deleterious",31.28,24.61,6322,45,6399,0.0070323488045007,6154,108,6288,0.017175572519084,1.35460818154012E-007,1,2,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_048",2,25470545,"A","T","DNMT3A","ENST00000264709","missense_variant","aTt/aAt|p.Ile310Asn/c.929T>A",3198,43,3257,0.013202333435677,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.033,"Deleterious",32.54,26.12,1635,19,1659,0.0114526823387583,1563,24,1598,0.0150187734668335,0.443055251553204,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_077",2,25470551,"C","T","DNMT3A","ENST00000264709","missense_variant","gGc/gAc|p.Gly308Asp/c.923G>A",2786,30,2828,0.0106082036775106,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4169957","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-3.953,"Deleterious",32.02,29.67,1406,16,1424,0.0112359550561798,1380,14,1404,0.00997150997150997,0.854977371066687,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_062",2,25470557,"C","T","DNMT3A","ENST00000264709","stop_gained","tGg/tAg|p.Trp306*/c.917G>A",2938,67,3018,0.0222001325381047,0,0,0,0,1,1,0,1,3,"NO","NO","COSM249798","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",32.69,29.46,1481,31,1517,0.020435069215557,1457,36,1501,0.0239840106595603,0.538032380893639,1,1,"Artifact (0)"]
["inspected, many artifacts","UPN_Tr2_044",2,25470558,"A","T","DNMT3A","ENST00000264709","missense_variant","Tgg/Agg|p.Trp306Arg/c.916T>A",3333,136,3517,0.0386693204435599,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-10.917,"Deleterious",29.47,30.38,1661,64,1772,0.036117381489842,1672,72,1745,0.0412607449856734,0.541299933009385,1,1,"Artifact (0)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_077",2,25470577,"T","A","DNMT3A","ENST00000264709","missense_variant","aaA/aaT|p.Lys299Asn/c.897A>T",2628,35,2764,0.0126628075253256,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.05,"Deleterious",26.84,19.91,1240,27,1355,0.0199261992619926,1388,8,1409,0.0056777856635912,0.000481670080846135,1,1,"Artifact (4)"]
["inspected, homopolymer 5C, strandbias","UPN_Tr2_046",2,25470579,"TC","T","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Lys299fs/c.894delG",6220,68,6317,0.0107646034510052,0,0,0,1,0,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.92,"NA",3,0,4,0,6217,68,6313,0.0107714240456201,1,2,2,"Artifact (4)"]
["homopolymer 5C, strandbias","UPN_Tr2_090",2,25470579,"TC","T","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Lys299fs/c.894delG",1795,30,1834,0.0163576881134133,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.61,"NA",0,0,0,"NA",1795,30,1834,0.0163576881134133,1,2,2,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_091",2,25470585,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgg/Ggg|p.Trp297Gly/c.889T>G",2091,23,2124,0.0108286252354049,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO",-8.706,"Deleterious",34.63,31.04,6,2,8,0.25,2085,21,2116,0.00992438563327032,0.00304785629674989,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_044",2,25470587,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val296Glu/c.887T>A",1688,52,1748,0.0297482837528604,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.382,"Deleterious",33.59,29.58,0,0,0,"NA",1688,52,1748,0.0297482837528604,1,1,1,"Artifact (0)"]
["inspected, many artifacts","UPN_Tr2_002",2,25470602,"C","T","DNMT3A","ENST00000264709","missense_variant","gGc/gAc|p.Gly291Asp/c.872G>A",2344,33,2381,0.0138597228055439,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.92,"Deleterious",34.6,32.97,17,0,17,0,2327,33,2364,0.0139593908629442,1,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_048",2,25470612,"G","A","DNMT3A","ENST00000264709","missense_variant","Cgg/Tgg|p.Arg288Trp/c.862C>T",1587,23,1613,0.0142591444513329,0,0,0,0,1,0,0,1,2,"NO","NO","COSM2911825","large_intestine",3,"NO","NO","NO",8.237E-006,"NO","NO",-3.066,"Deleterious",35.04,34.87,0,0,0,"NA",1587,23,1613,0.0142591444513329,1,1,1,"Artifact (1)"]
["low bq, many samples, no database","UPN_Tr2_062",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",2378,716,3107,0.230447376890892,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.01,21.44,1582,7,1597,0.00438321853475266,796,709,1510,0.46953642384106,6.64102572895587E-257,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_063",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",2133,610,2752,0.221656976744186,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.86,21.62,1393,5,1403,0.00356379187455453,740,605,1349,0.448480355819125,2.49659239178054E-216,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_064",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",1081,299,1385,0.215884476534296,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.86,21.33,707,1,710,0.00140845070422535,374,298,675,0.441481481481481,1.27514686294916E-110,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_065",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",488,117,610,0.191803278688525,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.71,20.97,314,0,316,0,174,117,294,0.397959183673469,1.54559916912926E-044,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_066",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",151,48,205,0.234146341463415,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.25,21.48,101,0,104,0,50,48,101,0.475247524752475,6.78118045317943E-019,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_067",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",295,82,381,0.215223097112861,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.32,21.46,195,0,197,0,100,82,184,0.445652173913043,5.32645119446996E-032,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_070",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",731,233,974,0.239219712525667,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.39,21.48,491,1,497,0.00201207243460765,240,232,477,0.486373165618449,2.01611082431395E-087,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_072",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",3267,929,4215,0.220403321470937,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.86,21.03,2161,4,2175,0.00183908045977011,1106,925,2040,0.45343137254902,0,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_075",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",2809,764,3577,0.213586804584848,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.03,21.27,1846,3,1852,0.00161987041036717,963,761,1725,0.441159420289855,3.98562523898474E-283,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_076",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",1378,373,1757,0.212293682413204,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.88,21.56,906,1,911,0.00109769484083425,472,372,846,0.439716312056738,4.59357983245065E-140,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_077",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",822,237,1063,0.222953904045155,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.89,21.48,541,1,544,0.00183823529411765,281,236,519,0.454720616570328,1.17292264562487E-087,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_078",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",1995,573,2576,0.222437888198758,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.1,21.24,1317,1,1322,0.00075642965204236,678,572,1254,0.456140350877193,3.16670424906779E-215,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_079",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",868,225,1094,0.205667276051188,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.77,22.43,557,1,558,0.0017921146953405,311,224,536,0.417910447761194,2.79234344915997E-081,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_080",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",2275,604,2890,0.208996539792388,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.85,21.26,1474,3,1483,0.00202292650033715,801,601,1407,0.427149964463397,2.24663759520359E-218,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_082",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",706,192,902,0.212860310421286,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.74,21.51,457,0,459,0,249,192,443,0.433408577878104,6.75430437291386E-072,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_084",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",1508,413,1933,0.213657527159855,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.88,21.79,980,2,988,0.00202429149797571,528,411,945,0.434920634920635,1.02608793047355E-149,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_085",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",618,170,793,0.21437578814628,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.78,20.92,406,1,409,0.00244498777506112,212,169,384,0.440104166666667,7.37157864896304E-063,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_086",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",275,63,338,0.186390532544379,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",27.38,21.63,175,0,175,0,100,63,163,0.386503067484663,4.90243762674423E-024,19,19,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_088",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",941,272,1224,0.222222222222222,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.187,"Tolerated",28.26,21.76,622,0,627,0,319,272,597,0.455611390284757,6.34419786042372E-104,19,19,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_084",2,25470980,"T","C","DNMT3A","ENST00000264709","missense_variant","Acg/Gcg|p.Thr261Ala/c.781A>G",1853,25,1946,0.012846865364851,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.029,"Tolerated",27.96,29.8,972,12,988,0.0121457489878543,881,13,958,0.0135699373695198,0.691035987058309,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_080",2,25470985,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","gct/|p.Ala259fs/c.775delG",2872,31,2920,0.0106164383561644,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.12,"NA",1464,16,1482,0.0107962213225371,1408,15,1438,0.0104311543810848,1,1,1,"Artifact (2)"]
["low bq, low freq, many artifacts, many samples","UPN_Tr2_034",2,25470992,"T","G","DNMT3A","ENST00000264709","missense_variant","Act/Cct|p.Thr257Pro/c.769A>C",5932,66,6036,0.010934393638171,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.237,"Tolerated",29.85,23.36,2943,20,2985,0.0067001675041876,2989,46,3051,0.0150770239265814,0.00184298235982761,1,1,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_061",2,25470998,"A","G","DNMT3A","ENST00000264709","missense_variant","Tcc/Ccc|p.Ser255Pro/c.763T>C",1737,22,1784,0.0123318385650224,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.417,"Tolerated",30.65,33.45,872,12,901,0.0133185349611543,865,10,883,0.0113250283125708,0.830799759417756,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_078",2,25471021,"A","G","DNMT3A","ENST00000264709","missense_variant","gTg/gCg|p.Val247Ala/c.740T>C",2508,58,2628,0.0220700152207002,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.274,"Tolerated",27.88,32.02,1235,30,1314,0.0228310502283105,1273,28,1314,0.0213089802130898,0.7908238156426,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_072",2,25471025,"C","T","DNMT3A","ENST00000264709","missense_variant","Gct/Act|p.Ala246Thr/c.736G>A",4238,47,4292,0.010950605778192,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.075,"Tolerated",31.89,32.72,2135,23,2158,0.0106580166821131,2103,24,2134,0.0112464854732896,0.884112309747105,1,1,"Artifact (4)"]
["inspected, low freq, neutral effect","UPN_Tr2_065",2,25471069,"T","C","DNMT3A","ENST00000264709","missense_variant","cAg/cGg|p.Gln231Arg/c.692A>G",310,22,337,0.0652818991097923,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.501,"Tolerated",33.8,32,0,22,27,0.814814814814815,310,0,310,0,7.84595900135999E-035,1,7,"Artifact (4)"]
["many samples","UPN_Tr2_059",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",561,31,605,0.0512396694214876,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.73,31.42,0,31,41,0.75609756097561,561,0,564,0,2.09020772235455E-052,6,7,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_061",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",883,32,918,0.0348583877995643,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.53,32.12,0,31,32,0.96875,883,1,886,0.00112866817155756,6.90746764542199E-057,6,7,"Artifact (5)"]
["many samples","UPN_Tr2_064",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",704,38,743,0.0511440107671602,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.76,30.76,0,36,36,1,704,2,707,0.00282885431400283,2.86890345290656E-059,6,7,"Artifact (6)"]
["inspected, strandbias, bad alignment","UPN_Tr2_066",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",104,36,140,0.257142857142857,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.69,31.08,0,36,36,1,104,0,104,0,2.84590844689986E-034,6,7,"Artifact (4)"]
["many samples","UPN_Tr2_076",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",898,22,925,0.0237837837837838,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.5,31.18,0,21,21,1,898,1,904,0.00110619469026549,8.14890535550573E-042,6,7,"Artifact (6)"]
["inspected, low freq, neutral effect","UPN_Tr2_083",2,25471069,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln231Pro/c.692A>C",1035,68,1107,0.0614272809394761,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.283,"Tolerated",33.17,31.15,0,67,67,1,1035,1,1040,0.000961538461538462,2.69462800055588E-107,6,7,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_043",2,25497815,"T","C","DNMT3A","ENST00000264709","missense_variant","Agg/Ggg|p.Arg212Gly/c.634A>G",2214,25,2265,0.011037527593819,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.185,"Tolerated",34.59,35.4,2214,25,2265,0.011037527593819,0,0,0,"NA",1,5,5,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_029",2,25497815,"T","C","DNMT3A","ENST00000264709","missense_variant","Agg/Ggg|p.Arg212Gly/c.634A>G",2201,24,2236,0.0107334525939177,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.185,"Tolerated",35.09,35.08,2201,24,2236,0.0107334525939177,0,0,0,"NA",1,5,5,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_010",2,25497815,"T","C","DNMT3A","ENST00000264709","missense_variant","Agg/Ggg|p.Arg212Gly/c.634A>G",1755,22,1787,0.0123111359820929,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.185,"Tolerated",34.98,36,1755,22,1787,0.0123111359820929,0,0,0,"NA",1,5,5,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_057",2,25497815,"T","C","DNMT3A","ENST00000264709","missense_variant","Agg/Ggg|p.Arg212Gly/c.634A>G",2561,30,2624,0.0114329268292683,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.185,"Tolerated",34.61,36,2561,30,2624,0.0114329268292683,0,0,0,"NA",1,5,5,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_071",2,25497815,"T","C","DNMT3A","ENST00000264709","missense_variant","Agg/Ggg|p.Arg212Gly/c.634A>G",1423,21,1449,0.0144927536231884,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.185,"Tolerated",34.58,35.43,1423,21,1449,0.0144927536231884,0,0,0,"NA",1,5,5,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_041",2,25497818,"T","C","DNMT3A","ENST00000264709","missense_variant","Aaa/Gaa|p.Lys211Glu/c.631A>G",1283,22,1317,0.0167046317388003,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","rs80021709","NO","NO","NO","NO",-0.233,"Tolerated",34.7,35.14,1283,22,1317,0.0167046317388003,0,0,0,"NA",1,1,1,"Artifact (3)"]
["Inspected, not in 2nd Illumina","UPN_Tr2_083",2,25497826,"G","A","DNMT3A","ENST00000264709","missense_variant","gCa/gTa|p.Ala208Val/c.623C>T",595,23,619,0.037156704361874,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.275,"Tolerated",34.68,33.39,595,23,619,0.037156704361874,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected","UPN_Tr2_056",2,25497835,"T","A","DNMT3A","ENST00000264709","missense_variant","gAg/gTg|p.Glu205Val/c.614A>T",1099,41,1145,0.0358078602620087,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.779,"Tolerated",34.51,31.76,1065,41,1110,0.0369369369369369,34,0,35,0,0.630575009427384,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_041",2,25497838,"T","C","DNMT3A","ENST00000264709","missense_variant","gAc/gGc|p.Asp204Gly/c.611A>G",1287,22,1314,0.0167427701674277,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.744,"Tolerated",34.53,34.45,1287,22,1314,0.0167427701674277,0,0,0,"NA",1,1,1,"Artifact (4)"]
["many samples, homopolymer 5C, low freq, no database","UPN_Tr2_055",2,25497868,"TC","T","DNMT3A","ENST00000264709","frameshift_variant","gac/|p.Asp194fs/c.580delG",6634,77,6726,0.0114481118049361,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.85,"NA",3288,39,3337,0.0116871441414444,3346,38,3389,0.0112127471230451,0.908907012240455,5,7,"Artifact (5)"]
["bad alignment, many artifacts, many samples","UPN_Tr2_059",2,25505377,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu127Asp/c.381A>C",5495,339,5881,0.0576432579493283,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.268,"Tolerated",22.78,15.83,2684,242,2942,0.0822569680489463,2811,97,2939,0.0330044232732222,3.18693385816049E-016,26,26,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_066",2,25505377,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu127Asp/c.381A>C",2705,162,2885,0.0561525129982669,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.268,"Tolerated",22.99,16.09,1325,113,1446,0.0781466113416321,1380,49,1439,0.034051424600417,2.55911923065263E-007,26,26,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_085",2,25505402,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu119Ala/c.356A>C",1959,284,2254,0.125998225377107,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.487,"Tolerated",18.73,15.24,0,0,0,"NA",1959,284,2254,0.125998225377107,1,4,4,"Artifact (4)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_014",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","cag/|p.Gln110fs/c.328delG",7442,115,7593,0.0151455287765047,0,0,1,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.89,"NA",0,0,0,"NA",7442,115,7593,0.0151455287765047,1,103,107,"Artifact (7)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_033",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",5894,75,5990,0.0125208681135225,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.87,"NA",0,0,0,"NA",5894,75,5990,0.0125208681135225,1,103,107,"Artifact (8)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_035",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",6146,105,6281,0.0167170832669957,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.89,"NA",0,0,0,"NA",6146,105,6281,0.0167170832669957,1,103,107,"Artifact (8)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_008",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",20258,220,20561,0.0106998686834298,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.76,"NA",0,0,0,"NA",20258,220,20561,0.0106998686834298,1,103,107,"Artifact (8)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_064",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",3490,62,3572,0.0173572228443449,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.14,"NA",0,0,0,"NA",3490,62,3572,0.0173572228443449,1,103,107,"Artifact (8)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_081",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",6627,101,6764,0.0149319929036073,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.17,"NA",0,0,0,"NA",6627,101,6764,0.0149319929036073,1,103,107,"Artifact (8)"]
["many samples, ins and del, homopolymer 6C, low freq, no database","UPN_Tr2_105",2,25505430,"GC","G","DNMT3A","ENST00000264709","frameshift_variant","ggg/|p.Gln110fs/c.327delG",6332,73,6434,0.0113459745104134,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.68,"NA",0,0,0,"NA",6332,73,6434,0.0113459745104134,1,103,107,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_022",2,25505498,"A","C","DNMT3A","ENST00000264709","missense_variant","cTa/cGa|p.Leu87Arg/c.260T>G",10815,111,10973,0.0101157386311856,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.695,"Tolerated",32.98,31.84,3649,1,3660,0.000273224043715847,7166,110,7313,0.0150417065499795,2,41,41,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_067",2,25505498,"A","C","DNMT3A","ENST00000264709","missense_variant","cTa/cGa|p.Leu87Arg/c.260T>G",1726,29,1762,0.0164585698070375,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.695,"Tolerated",31.7,31.24,12,0,12,0,1714,29,1750,0.0165714285714286,2,41,41,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_088",2,25505498,"A","C","DNMT3A","ENST00000264709","missense_variant","cTa/cGa|p.Leu87Arg/c.260T>G",2605,51,2669,0.0191082802547771,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.695,"Tolerated",31.7,31.78,14,0,14,0,2591,51,2655,0.0192090395480226,2,41,41,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_104",2,25505574,"T","C","DNMT3A","ENST00000264709","missense_variant","Agc/Ggc|p.Ser62Gly/c.184A>G",2361,28,2397,0.0116812682519816,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.631,"Tolerated",34.17,33.57,1171,14,1192,0.011744966442953,1190,14,1205,0.0116182572614108,1,6,6,"Artifact (6)"]
["many samples, ins and del, homopolymer 6G, low freq, no database","UPN_Tr2_050",2,25523008,"CG","C","DNMT3A","ENST00000264709","frameshift_variant","ccg/|p.Pro59fs/c.176delC",4560,50,4645,0.0107642626480086,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.92,"NA",4536,50,4621,0.0108201687946332,24,0,24,0,1,28,34,"Artifact (8)"]
["many samples, ins and del, homopolymer 6G, low freq, no database","UPN_Tr2_104",2,25523008,"CG","C","DNMT3A","ENST00000264709","frameshift_variant","ccg/|p.Pro59fs/c.176delC",2605,28,2640,0.0106060606060606,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.16,"NA",2603,28,2638,0.0106141015921152,2,0,2,0,1,28,34,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_036",2,198266476,"A","AT","SF3B1","ENST00000335508","frameshift_variant","atg/atgA|p.Ile787fs/c.2352_2353insA",3997,41,4005,0.0102372034956305,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.63,"NA",3997,41,4005,0.0102372034956305,0,0,0,"NA",1,1,88,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_024",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",2038,26,2081,0.0124939932724652,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.36,"NA",2038,26,2081,0.0124939932724652,0,0,0,"NA",1,87,88,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_052",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",3696,40,3762,0.0106326422115896,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.13,"NA",3696,40,3762,0.0106326422115896,0,0,0,"NA",1,87,88,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_057",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",5600,92,5721,0.0160811047019752,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.18,"NA",5600,92,5721,0.0160811047019752,0,0,0,"NA",1,87,88,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_079",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",3461,46,3526,0.0130459444129325,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.04,"NA",3461,46,3526,0.0130459444129325,0,0,0,"NA",1,87,88,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_096",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",3013,36,3061,0.0117608624632473,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.47,"NA",3013,36,3061,0.0117608624632473,0,0,0,"NA",1,87,88,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_103",2,198266476,"AT","A","SF3B1","ENST00000335508","frameshift_variant","aaa/|p.Ile787fs/c.2353delA",2485,30,2526,0.0118764845605701,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.42,"NA",2485,30,2526,0.0118764845605701,0,0,0,"NA",1,87,88,"Artifact (10)"]
["inspected, many artifacts","UPN_Tr2_044",2,198267324,"G","C","SF3B1","ENST00000335508","missense_variant","gCc/gGc|p.Ala678Gly/c.2033C>G",554,20,576,0.0347222222222222,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.153,"Deleterious",34.53,31.75,0,0,0,"NA",554,20,576,0.0347222222222222,1,1,1,"Artifact (0)"]
["many samples","UPN_Tr2_020",2,198267330,"C","G","SF3B1","ENST00000335508","missense_variant","gGc/gCc|p.Gly676Ala/c.2027G>C",7199,483,7700,0.0627272727272727,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.729,"Deleterious",32.53,31.36,5666,483,6156,0.0784600389863548,1533,0,1544,0,5.47825455537663E-049,81,81,"Artifact (7)"]
["many samples","UPN_Tr2_035",2,198267330,"C","G","SF3B1","ENST00000335508","missense_variant","gGc/gCc|p.Gly676Ala/c.2027G>C",10462,767,11265,0.068086995117621,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.729,"Deleterious",32.49,31.6,8377,766,9172,0.0835150457915395,2085,1,2093,0.000477783086478739,2.1109911198688E-069,81,81,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_054",2,198267330,"C","G","SF3B1","ENST00000335508","missense_variant","gGc/gCc|p.Gly676Ala/c.2027G>C",9939,160,10135,0.0157868771583621,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.729,"Deleterious",32.14,31.31,7867,160,8050,0.0198757763975155,2072,0,2085,0,1.40537623561476E-016,81,81,"Artifact (9)"]
["many samples","UPN_Tr2_071",2,198267330,"C","G","SF3B1","ENST00000335508","missense_variant","gGc/gCc|p.Gly676Ala/c.2027G>C",7478,451,7960,0.0566582914572864,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.729,"Deleterious",32.88,31.04,4214,449,4681,0.0959196752830592,3264,2,3279,0.000609942055504727,8.74460998780882E-104,81,81,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_081",2,198267330,"C","G","SF3B1","ENST00000335508","missense_variant","gGc/gCc|p.Gly676Ala/c.2027G>C",3731,46,3791,0.0121340015826959,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.729,"Deleterious",34.04,31.61,457,46,505,0.0910891089108911,3274,0,3286,0,8.33668571683042E-042,81,81,"Artifact (9)"]
["low freq, many artifacts, many samples","UPN_Tr2_044",2,198267717,"A","T","SF3B1","ENST00000335508","missense_variant","Tat/Aat|p.Tyr588Asn/c.1762T>A",2784,34,2820,0.0120567375886525,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.812,"Deleterious",34.28,27.94,0,0,0,"NA",2784,34,2820,0.0120567375886525,1,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_043",2,209113313,"T","C","IDH1","ENST00000345146","missense_variant","aAg/aGg|p.Lys65Arg/c.194A>G",3039,32,3105,0.0103059581320451,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.372,"Tolerated",34.38,34.94,3039,32,3105,0.0103059581320451,0,0,0,"NA",1,1,1,"Artifact (4)"]
["many samples, low freq","UPN_Tr2_016",4,106155331,"T","C","TET2","ENST00000380013","missense_variant","Ttt/Ctt|p.Phe78Leu/c.232T>C",4787,50,4870,0.0102669404517454,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.32,"Tolerated",33.94,33.72,2405,25,2450,0.0102040816326531,2382,25,2420,0.0103305785123967,1,17,17,"Artifact (6)"]
["many samples, low freq","UPN_Tr2_057",4,106155331,"T","C","TET2","ENST00000380013","missense_variant","Ttt/Ctt|p.Phe78Leu/c.232T>C",7631,93,7778,0.0119568012342505,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.32,"Tolerated",33.47,32.65,3847,46,3929,0.0117078136930517,3784,47,3849,0.0122109638867238,0.917008365902774,17,17,"Artifact (6)"]
["homo TC, many samples","UPN_Tr2_059",4,106155402,"TTC","T","TET2","ENST00000380013","frameshift_variant","tct/|p.Ser104fs/c.311_312delCT",53232,1012,54519,0.0185623360663255,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.17,"NA",28428,922,29507,0.0312468227878131,24804,90,25012,0.00359827282904206,2,32,32,"Artifact (2)"]
["homo TC, many samples","UPN_Tr2_072",4,106155402,"TTC","T","TET2","ENST00000380013","frameshift_variant","tct/|p.Ser104fs/c.311_312delCT",31226,349,31734,0.010997668116216,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.05,"NA",13747,283,14116,0.0200481722867668,17479,66,17618,0.00374616869111136,2,32,32,"Artifact (3)"]
["homo TC, many samples","UPN_Tr2_087",4,106155402,"TTC","T","TET2","ENST00000380013","frameshift_variant","tct/|p.Ser104fs/c.311_312delCT",49454,662,50373,0.0131419609711552,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.14,"NA",24408,584,25134,0.0232354579454126,25046,78,25239,0.00309045524783074,2,32,32,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_044",4,106155419,"T","C","TET2","ENST00000380013","missense_variant","cTt/cCt|p.Leu107Pro/c.320T>C",5005,65,5093,0.012762615354408,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.574,"Tolerated",34.73,35.14,4498,47,4567,0.0102912196190059,507,18,526,0.0342205323193916,2,1,1,"Artifact (3)"]
["low freq, many samples, bad alignment","UPN_Tr2_017",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",12093,1051,13195,0.079651383099659,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.67,31.93,5382,1019,6413,0.158895992515204,6711,32,6782,0.00471837216160425,8.75775422117744E-286,108,108,"Artifact (5)"]
["inspected, bad alignment, strandbias, many samples","UPN_Tr2_043",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",27911,1011,29103,0.0347386867333265,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.47,31.76,10981,930,11942,0.0778764026126277,16930,81,17161,0.004720004661733,5.40582763619219E-265,108,108,"Artifact (5)"]
["low freq, many samples, bad alignment","UPN_Tr2_050",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",34609,911,35701,0.0255174925072127,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.27,31.78,15320,803,16152,0.0497152055473006,19289,108,19549,0.00552457926236636,1.11938535510438E-165,108,108,"Artifact (5)"]
["low freq, many samples, bad alignment","UPN_Tr2_058",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",45008,2546,47829,0.0532313031842606,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.28,31.68,19699,2454,22203,0.110525604648021,25309,92,25626,0.00359010380082728,0,108,108,"Artifact (5)"]
["low freq, many samples, bad alignment","UPN_Tr2_069",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",51121,5003,56296,0.0888695466818246,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.24,31.63,25464,4907,30427,0.161271239359779,25657,96,25869,0.00371100545053926,0,108,108,"Artifact (5)"]
["low freq, many samples, bad alignment","UPN_Tr2_083",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",52676,5642,58515,0.0964197214389473,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.33,31.56,24858,5538,30458,0.181824151290301,27818,104,28057,0.00370673985101757,0,108,108,"Artifact (5)"]
["low freq, many samples, bad alignment","UPN_Tr2_107",4,106155682,"A","G","TET2","ENST00000380013","missense_variant","Aag/Gag|p.Lys195Glu/c.583A>G",40626,1108,41824,0.0264919663351186,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.748,"Tolerated",33.62,31.73,18990,1044,20059,0.0520464629343437,21636,64,21765,0.00294050080404319,3.75986456573264E-252,108,108,"Artifact (5)"]
["low bq, low freq, many artifacts, many samples","UPN_Tr2_042",4,106155832,"A","C","TET2","ENST00000380013","missense_variant","Acc/Ccc|p.Thr245Pro/c.733A>C",10257,105,10427,0.0100700105495349,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.792,"Tolerated",30.53,24.61,4878,84,4993,0.0168235529741638,5379,21,5434,0.00386455649613544,1.78188956834675E-011,2,2,"Artifact (5)"]
["strandbias, many samples","UPN_Tr2_024",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",13253,767,14059,0.0545558005548048,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.74,31.83,5938,741,6694,0.110696145802211,7315,26,7365,0.00353021045485404,1.21930584280555E-207,109,109,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_031",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",16483,1094,17636,0.0620322068496258,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.8,31.75,7388,1062,8482,0.125206319264324,9095,32,9154,0.00349573956740223,3.56735128798985E-301,109,109,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_008",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",69116,7168,76531,0.0936613921156133,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.85,31.55,29531,7061,36700,0.192397820163488,39585,107,39831,0.0026863498280234,0,109,109,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_060",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",33450,2379,35918,0.0662342001225013,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.88,31.51,12293,2311,14642,0.157833629285617,21157,68,21276,0.00319608949050573,0,109,109,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_077",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",35887,3177,39187,0.0810728047566795,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.53,31.64,16925,3111,20085,0.154891710231516,18962,66,19102,0.00345513558789656,0,109,109,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_086",4,106156012,"A","G","TET2","ENST00000380013","missense_variant","Agt/Ggt|p.Ser305Gly/c.913A>G",24994,2257,27315,0.0826285923485264,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.004,"Tolerated",33.36,31.55,13283,2218,15537,0.14275600180215,11711,39,11778,0.0033112582781457,0,109,109,"Artifact (7)"]
["low bq, low freq, many artifacts","UPN_Tr2_044",4,106156156,"T","A","TET2","ENST00000380013","missense_variant","Tgt/Agt|p.Cys353Ser/c.1057T>A",6406,77,6495,0.011855273287144,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.46,"Tolerated",33.2,27.78,3152,50,3207,0.0155908949173683,3254,27,3288,0.00821167883211679,0.00795412590708055,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_044",4,106156230,"T","TG","TET2","ENST00000380013","frameshift_variant","ggt/ggGt|p.Ala379fs/c.1133dupG",4428,48,4464,0.010752688172043,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.6,"NA",1164,0,1177,0,3264,48,3287,0.0146029814420444,2,1,1,"Artifact (3)"]
["low freq, many artifacts, many samples","UPN_Tr2_017",4,106156288,"ACAC","A","TET2","ENST00000380013","inframe_deletion","cca/|p.Pro401del/c.1201_1203delCCA",7503,77,7605,0.0101249178,0,0,0,1,0,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.078,"Tolerated",34.28,"NA",3781,39,3832,0.010177453,3722,38,3773,0.0100715611,1,83,83,"Artifact (18)"]
["CAC repeat, many artifacts, low freq, many samples","UPN_Tr2_006",4,106156288,"ACAC","A","TET2","ENST00000380013","inframe_deletion","cca/|p.Pro401del/c.1201_1203delCCA",15835,247,16236,0.0152131067,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.078,"Tolerated",34.37,"NA",7985,126,8186,0.0153921329,7850,121,8050,0.0150310559,0.8979888332,83,83,"Artifact (13)"]
["CAC repeat, many artifacts, low freq, many samples","UPN_Tr2_010",4,106156288,"ACAC","A","TET2","ENST00000380013","inframe_deletion","cca/|p.Pro401del/c.1201_1203delCCA",25472,320,25869,0.0123700182,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.078,"Tolerated",34.38,"NA",12840,162,13037,0.0124261717,12632,158,12832,0.0123129676,0.9551799536,83,83,"Artifact (14)"]
["CAC repeat, many artifacts, low freq, many samples","UPN_Tr2_072",4,106156288,"ACAC","A","TET2","ENST00000380013","inframe_deletion","cca/|p.Pro401del/c.1201_1203delCCA",15487,158,15707,0.0100592093,0,0,0,1,0,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.078,"Tolerated",33.31,"NA",7849,81,7952,0.0101861167,7638,77,7755,0.009929078,0.9363025012,83,83,"Artifact (17)"]
["CAC repeat, many artifacts, low freq, many samples","UPN_Tr2_086",4,106156288,"ACAC","A","TET2","ENST00000380013","inframe_deletion","cca/|p.Pro401del/c.1201_1203delCCA",24115,289,24511,0.0117906246,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.078,"Tolerated",33.43,"NA",12199,145,12393,0.0117001533,11916,144,12118,0.011883149,0.9058742661,83,83,"Artifact (13)"]
["many samples, low freq, no database","UPN_Tr2_063",4,106156300,"C","T","TET2","ENST00000380013","missense_variant","Cca/Tca|p.Pro401Ser/c.1201C>T",17069,199,17405,0.0114334961218041,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.075,"Tolerated",32.45,32.89,8632,98,8786,0.0111541088094696,8437,101,8619,0.0117182967861701,0.721953170735192,9,9,"Artifact (6)"]
["many samples","UPN_Tr2_021",4,106156348,"C","G","TET2","ENST00000380013","missense_variant","Cag/Gag|p.Gln417Glu/c.1249C>G",12899,321,13250,0.0242264150943396,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.33,"Tolerated",33.21,31.07,7383,316,7716,0.0409538621047175,5516,5,5534,0.000903505601734731,2.3073552566865E-067,77,77,"Artifact (9)"]
["strandbias, many samples","UPN_Tr2_034",4,106156348,"C","G","TET2","ENST00000380013","missense_variant","Cag/Gag|p.Gln417Glu/c.1249C>G",5797,130,5943,0.021874474171294,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.33,"Tolerated",33.29,31.68,3252,128,3391,0.037746977292834,2545,2,2552,0.000783699059561128,4.08186830199272E-029,77,77,"Artifact (8)"]
["many samples","UPN_Tr2_011",4,106156348,"C","G","TET2","ENST00000380013","missense_variant","Cag/Gag|p.Gln417Glu/c.1249C>G",32670,867,33615,0.0257920571173583,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.33,"Tolerated",33.22,31.08,17352,851,18259,0.0466071526370557,15318,16,15356,0.00104193800468872,3.46010709408189E-202,77,77,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_071",4,106156348,"C","G","TET2","ENST00000380013","missense_variant","Cag/Gag|p.Gln417Glu/c.1249C>G",10791,210,11026,0.019045891529113,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.33,"Tolerated",33.65,30.81,3298,200,3508,0.0570125427594071,7493,10,7518,0.00133014099494546,5.53759017554691E-087,77,77,"Artifact (10)"]
["strandbias, many samples","UPN_Tr2_086",4,106156348,"C","G","TET2","ENST00000380013","missense_variant","Cag/Gag|p.Gln417Glu/c.1249C>G",19743,279,20093,0.0138854327377694,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.33,"Tolerated",33.48,30.43,7607,260,7894,0.0329364073980238,12136,19,12199,0.00155750471350111,3.08301405939462E-082,77,77,"Artifact (9)"]
["low bq, many samples, no database, low freq","UPN_Tr2_081",4,106156403,"A","C","TET2","ENST00000380013","missense_variant","cAc/cCc|p.His435Pro/c.1304A>C",7014,102,7163,0.0142398436409326,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.058,"Tolerated",30.26,26.27,7013,32,7074,0.00452360757704269,1,70,89,0.786516853932584,8.00605210839716E-142,14,14,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_044",4,106156612,"A","C","TET2","ENST00000380013","missense_variant","Aca/Cca|p.Thr505Pro/c.1513A>C",4974,54,5063,0.0106656132727632,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.821,"Tolerated",34.12,31.74,2521,28,2557,0.0109503324208056,2453,26,2506,0.0103750997605746,0.891911262843956,2,2,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_022",4,106156710,"G","C","TET2","ENST00000380013","missense_variant","gaG/gaC|p.Glu537Asp/c.1611G>C",18699,253,18996,0.0133185933880817,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.518,"Tolerated",32.71,31.08,4854,1,4864,0.000205592105263158,13845,252,14132,0.0178318709312199,2,72,72,"Artifact (9)"]
["many samples","UPN_Tr2_006",4,106156710,"G","C","TET2","ENST00000380013","missense_variant","gaG/gaC|p.Glu537Asp/c.1611G>C",16561,513,17088,0.0300210674157303,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.518,"Tolerated",32.61,31.56,4287,1,4293,0.000232937339855579,12274,512,12795,0.0400156311059007,2,72,72,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_013",4,106156710,"G","C","TET2","ENST00000380013","missense_variant","gaG/gaC|p.Glu537Asp/c.1611G>C",8899,179,9095,0.0196811434854316,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.518,"Tolerated",32.57,31.66,2198,2,2205,0.00090702947845805,6701,177,6890,0.025689404934688,2,72,72,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_076",4,106156710,"G","C","TET2","ENST00000380013","missense_variant","gaG/gaC|p.Glu537Asp/c.1611G>C",25388,524,25959,0.0201856774143842,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.518,"Tolerated",32.84,31.42,9914,7,9941,0.000704154511618549,15474,517,16018,0.0322761892870521,2,72,72,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_079",4,106156710,"G","C","TET2","ENST00000380013","missense_variant","gaG/gaC|p.Glu537Asp/c.1611G>C",14861,275,15171,0.0181266890778459,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.518,"Tolerated",32.96,30.68,6300,6,6315,0.000950118764845606,8561,269,8856,0.0303748870822042,2,72,72,"Artifact (9)"]
["many samples, ins and del, low freq","UPN_Tr2_040",4,106156935,"T","TG","TET2","ENST00000380013","frameshift_variant","ctc/Gctc|p.Leu615fs/c.1842dupG",53302,918,53820,0.017056856187291,1,0,0,1,1,0,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.47,"NA",26718,459,27045,0.0169717138103161,26584,459,26775,0.0171428571428571,0.946939439614622,4,109,"Artifact (4)"]
["many samples, ins and del, low freq","UPN_Tr2_017",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",14332,171,14547,0.0117550010311404,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",31.61,"NA",7188,85,7302,0.0116406463982471,7144,86,7245,0.0118702553485162,0.938754027503125,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_047",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",69199,992,70538,0.0140633417448751,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",31.48,"NA",34858,481,35535,0.0135359504713663,34341,511,35003,0.0145987486786847,0.2496436620805,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_050",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",43031,661,43916,0.0150514618817743,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",31.57,"NA",21673,320,22119,0.014467200144672,21358,341,21797,0.0156443547277148,0.327274340578099,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_055",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",55861,889,57076,0.015575723596608,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",31.53,"NA",28128,432,28741,0.0150307922480081,27733,457,28335,0.0161284630315864,0.310514338635764,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_071",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",37974,434,38674,0.0112220096188654,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",30.9,"NA",19026,209,19420,0.0107621009268795,18948,225,19254,0.011685883452789,0.439958649068747,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_082",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",72352,872,73778,0.0118192415083087,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",30.83,"NA",36302,426,37093,0.0114846466988381,36050,446,36685,0.0121575575848439,0.453592564700147,105,109,"Artifact (8)"]
["many samples, ins and del, low freq","UPN_Tr2_110",4,106156935,"TG","T","TET2","ENST00000380013","frameshift_variant","ggg/|p.Leu615fs/c.1842delG",39763,436,40351,0.0108051845059602,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",31.21,"NA",19924,216,20223,0.0106809078771696,19839,220,20128,0.0109300476947536,0.84729178636241,105,109,"Artifact (8)"]
["low freq, many samples","UPN_Tr2_035",4,106156986,"C","A","TET2","ENST00000380013","missense_variant","caC/caA|p.His629Gln/c.1887C>A",57819,674,58633,0.011495233059881,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.409,"Tolerated",35.4,34.6,32602,657,33322,0.0197167036792509,25217,17,25311,0.00067164473944135,2,18,18,"Artifact (5)"]
["low freq, many samples","UPN_Tr2_022",4,106157021,"G","C","TET2","ENST00000380013","missense_variant","gGg/gCg|p.Gly641Ala/c.1922G>C",35833,773,36673,0.0210781774057208,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.7,"Tolerated",33.64,31.27,20609,20,20661,0.000968007356855912,15224,753,16012,0.0470272295778166,2,81,81,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_042",4,106157021,"G","C","TET2","ENST00000380013","missense_variant","gGg/gCg|p.Gly641Ala/c.1922G>C",70167,712,71077,0.0100173051760766,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.7,"Tolerated",33.07,29.59,38494,81,38696,0.00209323961132934,31673,631,32381,0.0194867360489176,2,81,81,"Artifact (9)"]
["low freq, many samples","UPN_Tr2_011",4,106157021,"G","C","TET2","ENST00000380013","missense_variant","gGg/gCg|p.Gly641Ala/c.1922G>C",67174,2388,69773,0.0342252733865535,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.7,"Tolerated",33.35,31.39,36196,38,36354,0.00104527699840458,30978,2350,33419,0.0703192794518089,2,81,81,"Artifact (6)"]
["low freq, many samples","UPN_Tr2_060",4,106157021,"G","C","TET2","ENST00000380013","missense_variant","gGg/gCg|p.Gly641Ala/c.1922G>C",42114,1947,44188,0.0440617362179777,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.7,"Tolerated",32.57,31.08,15725,45,15825,0.0028436018957346,26389,1902,28363,0.0670591968409548,2,81,81,"Artifact (6)"]
["inspected, low freq, neutral effect","UPN_Tr2_085",4,106157021,"G","C","TET2","ENST00000380013","missense_variant","gGg/gCg|p.Gly641Ala/c.1922G>C",46578,1672,48373,0.0345647365265747,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.7,"Tolerated",32.78,30.52,21365,83,21512,0.00385831164001488,25213,1589,26861,0.0591563977513868,2,81,81,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_044",4,106157087,"C","A","TET2","ENST00000380013","missense_variant","tCc/tAc|p.Ser663Tyr/c.1988C>A",15109,159,15317,0.0103806228373702,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.822,"Tolerated",33.4,29.25,7492,80,7595,0.010533245556287,7617,79,7722,0.0102305102305102,0.873574352827396,1,1,"Artifact (4)"]
["many samples","UPN_Tr2_017",4,106157294,"C","G","TET2","ENST00000380013","missense_variant","cCa/cGa|p.Pro732Arg/c.2195C>G",9511,337,9885,0.0340920586747597,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.13,"Tolerated",32.94,31.57,6381,336,6748,0.0497925311203319,3130,1,3137,0.000318775900541919,1.41160680804299E-055,85,85,"Artifact (9)"]
["strandbias, many samples","UPN_Tr2_029",4,106157294,"C","G","TET2","ENST00000380013","missense_variant","cCa/cGa|p.Pro732Arg/c.2195C>G",21335,777,22172,0.0350441998917554,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.13,"Tolerated",32.71,31.55,15755,775,16574,0.0467599855194884,5580,2,5598,0.000357270453733476,2.95265899884035E-096,85,85,"Artifact (8)"]
["strandbias, many samples","UPN_Tr2_049",4,106157294,"C","G","TET2","ENST00000380013","missense_variant","cCa/cGa|p.Pro732Arg/c.2195C>G",21769,437,22281,0.0196131232889009,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.13,"Tolerated",32.36,31.48,16837,433,17329,0.0249870159847654,4932,4,4952,0.000807754442649435,1.00006519728158E-041,85,85,"Artifact (10)"]
["strandbias, many samples","UPN_Tr2_040",4,106157294,"C","G","TET2","ENST00000380013","missense_variant","cCa/cGa|p.Pro732Arg/c.2195C>G",37962,1164,39213,0.0296840333562849,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.13,"Tolerated",32.75,31.67,27415,1157,28646,0.0403895831878796,10547,7,10567,0.000662439670672849,1.69423043608663E-147,85,85,"Artifact (8)"]
["strandbias, many samples","UPN_Tr2_074",4,106157294,"C","G","TET2","ENST00000380013","missense_variant","cCa/cGa|p.Pro732Arg/c.2195C>G",25069,895,26034,0.0343781209187985,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.13,"Tolerated",32.65,31.38,17176,882,18114,0.0486916197416363,7893,13,7920,0.00164141414141414,1.93930101166123E-120,85,85,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_052",4,106157317,"C","A","TET2","ENST00000380013","missense_variant","Caa/Aaa|p.Gln740Lys/c.2218C>A",23784,251,24079,0.0104240209311018,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.78,"Tolerated",35.36,34.21,18355,249,18636,0.0133612363168062,5429,2,5443,0.000367444424030865,2,2,2,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_080",4,106157352,"G","C","TET2","ENST00000380013","missense_variant","aaG/aaC|p.Lys751Asn/c.2253G>C",34502,476,35047,0.0135817616343767,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.204,"Tolerated",33.35,30.56,18682,25,18745,0.00133368898372899,15820,451,16302,0.0276653171390014,2,18,18,"Artifact (5)"]
["inspected, strandbias","UPN_Tr2_056",4,106157657,"T","C","TET2","ENST00000380013","missense_variant","cTt/cCt|p.Leu853Pro/c.2558T>C",1204,53,1265,0.041897233201581,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.005,"Tolerated",34.66,32.25,1204,6,1218,0.00492610837438424,0,47,47,1,3.04097332895753E-079,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_073",4,106157943,"G","C","TET2","ENST00000380013","missense_variant","aaG/aaC|p.Lys948Asn/c.2844G>C",1134,21,1157,0.0181503889369058,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.513,"Tolerated",34.43,30.29,2,19,21,0.904761904761905,1132,2,1136,0.00176056338028169,4.01481144653835E-037,5,5,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_041",4,106157944,"C","G","TET2","ENST00000380013","missense_variant","Cat/Gat|p.His949Asp/c.2845C>G",20739,280,21092,0.0132751754219609,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.018,"Tolerated",31.81,31.61,20695,280,21048,0.0133029266438616,44,0,44,0,1,84,84,"Artifact (10)"]
["many samples, strandbias","UPN_Tr2_047",4,106157944,"C","G","TET2","ENST00000380013","missense_variant","Cat/Gat|p.His949Asp/c.2845C>G",30292,627,31056,0.0201893353941267,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.018,"Tolerated",31.88,31.38,29112,622,29841,0.0208438055024966,1180,5,1215,0.00411522633744856,4.25101235876871E-006,84,84,"Artifact (7)"]
["many samples","UPN_Tr2_009",4,106157944,"C","G","TET2","ENST00000380013","missense_variant","Cat/Gat|p.His949Asp/c.2845C>G",37281,854,38268,0.0223162955994565,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.018,"Tolerated",33.08,31.41,22303,846,23243,0.036398055328486,14978,8,15025,0.000532445923460898,6.09441005733624E-171,84,84,"Artifact (8)"]
["many samples, strandbias","UPN_Tr2_069",4,106157944,"C","G","TET2","ENST00000380013","missense_variant","Cat/Gat|p.His949Asp/c.2845C>G",37758,1049,38927,0.0269478767950266,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.018,"Tolerated",33.08,31.2,19846,1024,20941,0.0488992884771501,17912,25,17986,0.0013899699766485,1.42249679495179E-239,84,84,"Artifact (6)"]
["many samples","UPN_Tr2_081",4,106157944,"C","G","TET2","ENST00000380013","missense_variant","Cat/Gat|p.His949Asp/c.2845C>G",23958,873,24887,0.0350785550689115,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.018,"Tolerated",31.86,31.32,23176,872,24104,0.0361765682044474,782,1,783,0.00127713920817369,2.02627443819001E-011,84,84,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_004",4,106157997,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln966His/c.2898G>C",4162,59,4231,0.0139446939257859,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.417,"Tolerated",34,31.39,2938,0,2944,0,1224,59,1287,0.0458430458430458,2,56,56,"Artifact (9)"]
["many samples, strandbias","UPN_Tr2_038",4,106157997,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln966His/c.2898G>C",40451,517,41084,0.0125839742965631,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.417,"Tolerated",33.79,31.18,23533,13,23607,0.000550684119117211,16918,504,17477,0.0288379012416319,2,56,56,"Artifact (8)"]
["many samples, strandbias","UPN_Tr2_011",4,106157997,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln966His/c.2898G>C",33963,484,34526,0.0140184209001912,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.417,"Tolerated",33.84,30.55,22075,32,22152,0.00144456482484652,11888,452,12374,0.0365282042993373,2,56,56,"Artifact (8)"]
["low freq, many artifacts","UPN_Tr2_044",4,106158047,"T","A","TET2","ENST00000380013","missense_variant","gTg/gAg|p.Val983Glu/c.2948T>A",7797,81,7897,0.0102570596429024,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.3,"Tolerated",31.98,27.17,3849,54,3913,0.0138001533350371,3948,27,3984,0.00677710843373494,0.00236773551301849,1,1,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_015",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",33987,1416,35486,0.0399030603618328,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.53,35.49,16160,1407,17615,0.0798751064433721,17827,9,17871,0.000503609199261373,2,109,109,"Artifact (4)"]
["many samples","UPN_Tr2_005",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",6087,192,6286,0.0305440661788101,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.42,35.42,3268,191,3461,0.055186362323028,2819,1,2825,0.000353982300884956,2,109,109,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_039",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",37512,1528,39151,0.0390283773083702,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.5,35.36,18003,1501,19581,0.0766559419845769,19509,27,19570,0.00137966274910577,2,109,109,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_056",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",17671,291,18020,0.0161487236403996,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.3,34.54,8331,271,8629,0.0314057248812145,9340,20,9391,0.00212969864764136,2,109,109,"Artifact (6)"]
["many samples, strandbias","UPN_Tr2_072",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",25848,545,26464,0.0205940145102781,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.23,35,12357,541,12936,0.0418212739641311,13491,4,13528,0.000295683027794205,2,109,109,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_082",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",54287,2686,57131,0.0470147555617791,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.2,35.14,26286,2646,29028,0.0911533691608103,28001,40,28103,0.00142333558694801,2,109,109,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_108",4,106158139,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1014Ser/c.3040G>T",30303,1021,31386,0.0325304275791754,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","rs145019756","NO","NO","NO","NO",0.463,"Tolerated",35.53,35.5,13879,1017,14924,0.0681452693647816,16424,4,16462,0.000242983841574535,2,109,109,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_021",4,106158342,"A","C","TET2","ENST00000380013","missense_variant","ttA/ttC|p.Leu1081Phe/c.3243A>C",15263,174,15513,0.0112163991491008,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.845,"Tolerated",33.38,31.29,6748,0,6768,0,8515,174,8745,0.0198970840480274,2,33,33,"Artifact (6)"]
["many samples, low freq, many artifacts","UPN_Tr2_066",4,106158342,"A","C","TET2","ENST00000380013","missense_variant","ttA/ttC|p.Leu1081Phe/c.3243A>C",62280,872,63408,0.0137522079232904,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.845,"Tolerated",33.35,31.28,30979,8,31079,0.000257408539528299,31301,864,32329,0.0267252312165548,2,33,33,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_041",4,106158368,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1090Arg/c.3269A>G",3593,46,3646,0.0126165660998354,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO",8.237E-006,"NO","NO",-0.959,"Tolerated",34.97,33.33,3593,46,3646,0.0126165660998354,0,0,0,"NA",1,40,40,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_089",4,106158368,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1090Arg/c.3269A>G",7003,73,7080,0.0103107344632768,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO",8.237E-006,"NO","NO",-0.959,"Tolerated",35.4,34.88,6996,73,7073,0.0103209387812809,7,0,7,0,1,40,40,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_102",4,106158368,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1090Arg/c.3269A>G",6396,73,6474,0.0112758727216559,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO",8.237E-006,"NO","NO",-0.959,"Tolerated",35.38,34.58,6396,73,6474,0.0112758727216559,0,0,0,"NA",1,40,40,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_110",4,106158368,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1090Arg/c.3269A>G",6603,69,6676,0.0103355302576393,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO",8.237E-006,"NO","NO",-0.959,"Tolerated",35.42,34.81,6602,69,6675,0.0103370786516854,1,0,1,0,1,40,40,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_042",4,106158446,"TA","T","TET2","ENST00000380013","frameshift_variant","aat/|p.Asn1118fs/c.3353delA",12988,155,13174,0.0117655989069379,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.36,"NA",6,0,6,0,12982,155,13168,0.0117709599027947,1,72,72,"Artifact (9)"]
["low freq, many artifacts, many samples","UPN_Tr2_039",4,106158446,"TA","T","TET2","ENST00000380013","frameshift_variant","aat/|p.Asn1118fs/c.3353delA",14856,160,15067,0.0106192340877414,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.48,"NA",0,0,0,"NA",14856,160,15067,0.0106192340877414,1,72,72,"Artifact (9)"]
["low freq, many artifacts, many samples","UPN_Tr2_065",4,106158446,"TA","T","TET2","ENST00000380013","frameshift_variant","aat/|p.Asn1118fs/c.3353delA",18761,209,19032,0.0109815048339639,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.41,"NA",0,0,0,"NA",18761,209,19032,0.0109815048339639,1,72,72,"Artifact (9)"]
["low freq, many artifacts, many samples","UPN_Tr2_083",4,106158446,"TA","T","TET2","ENST00000380013","frameshift_variant","aat/|p.Asn1118fs/c.3353delA",20238,221,20506,0.0107773334633766,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.41,"NA",0,0,0,"NA",20238,221,20506,0.0107773334633766,1,72,72,"Artifact (9)"]
["inspected, many artifacts","UPN_Tr2_044",4,106164035,"A","T","TET2","ENST00000380013","missense_variant","tAt/tTt|p.Tyr1182Phe/c.3545A>T",6920,196,7143,0.0274394512109758,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.18,"Deleterious",32.46,29.26,3523,83,3620,0.0229281767955801,3397,113,3523,0.0320749361339767,0.0202674891537,1,1,"Artifact (0)"]
["low freq, many artifacts","UPN_Tr2_048",4,106164892,"A","T","TET2","ENST00000380013","stop_gained","Aaa/Taa|p.Lys1254*/c.3760A>T",2222,43,2276,0.0188927943760984,0,0,0,0,1,0,0,1,2,"NO","NO","COSM110776","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",34.9,29.95,0,0,0,"NA",2222,43,2276,0.0188927943760984,1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_035",4,106190854,"T","C","TET2","ENST00000380013","missense_variant","Tgt/Cgt|p.Cys1378Arg/c.4132T>C",14251,233,14517,0.016050148102225,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-11.019,"Deleterious",32.03,30.86,7170,118,7313,0.0161356488445235,7081,115,7204,0.0159633536923931,0.947385742441262,2,2,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_041",4,106193740,"A","T","TET2","ENST00000380013","missense_variant","gAa/gTa|p.Glu1401Val/c.4202A>T",1351,27,1383,0.0195227765726681,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.658,"Deleterious",35.49,34.22,1351,27,1383,0.0195227765726681,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_080",4,106193971,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1478Arg/c.4433A>G",5164,53,5222,0.0101493680582152,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.716,"Tolerated",33.35,33.34,5164,53,5222,0.0101493680582152,0,0,0,"NA",1,8,8,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_044",4,106196232,"T","C","TET2","ENST00000380013","missense_variant","aTg/aCg|p.Met1522Thr/c.4565T>C",2741,52,2803,0.0185515519086693,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.805,"Tolerated",34.68,34.56,1091,44,1140,0.0385964912280702,1650,8,1663,0.00481058328322309,2,1,1,"Artifact (3)"]
["many samples, many artifacts","UPN_Tr2_081",4,106196240,"TCCCAGCAGCCCCAGCCTCTACAGAAGCAGCCACCACAGCCCCAGCAGCAGCAGAGAC","T","TET2","ENST00000380013","disruptive_inframe_deletion","ccccagcctctacagaagcagccaccacagccccagcagcagcagagaccccagcagcag/cag|p.Pro1528_Gln1546del/c.4583_4639delCCCAGCCTCTACAGAAGCAGCCACCACAGCCCCAGCAGCAGCAGAGACCCCAGCAGC",2606,"NA",2618,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-12.298,"Deleterious",34.61,"NA",1237,"NA",1242,"NA",1369,"NA",1376,"NA",2,4,10,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_005",4,106196283,"A","C","TET2","ENST00000380013","missense_variant","cAg/cCg|p.Gln1539Pro/c.4616A>C",1910,26,1952,0.0133196721311475,0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.385,"Tolerated",33.89,32.58,601,12,616,0.0194805194805195,1309,14,1336,0.0104790419161677,2,1,1,"Artifact (4)"]
["low freq, many samples, low bq","UPN_Tr2_006",4,106196301,"A","C","TET2","ENST00000380013","missense_variant","cAg/cCg|p.Gln1545Pro/c.4634A>C",5146,73,5248,0.0139100609756098,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.804,"Tolerated",30.1,28.36,2569,16,2593,0.00617045892788276,2577,57,2655,0.0214689265536723,2,55,55,"Artifact (5)"]
["low freq, many samples, low bq","UPN_Tr2_060",4,106196301,"A","C","TET2","ENST00000380013","missense_variant","cAg/cCg|p.Gln1545Pro/c.4634A>C",5902,102,6052,0.0168539325842697,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.804,"Tolerated",30.83,29.66,743,11,757,0.0145310435931308,5159,91,5295,0.0171860245514636,2,55,55,"Artifact (5)"]
["low bq, low freq, many artifacts, many samples","UPN_Tr2_081",4,106196301,"A","C","TET2","ENST00000380013","missense_variant","cAg/cCg|p.Gln1545Pro/c.4634A>C",2641,45,2709,0.0166112956810631,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.804,"Tolerated",29.4,23.36,1297,21,1319,0.0159211523881729,1344,24,1390,0.0172661870503597,2,55,55,"Artifact (6)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_010",4,106196302,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln1545His/c.4635G>C",5493,86,5617,0.0153106640555457,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.004,"Tolerated",26.34,19.58,2835,18,2861,0.00629150646627053,2658,68,2756,0.0246734397677794,1.06544988832565E-008,4,4,"Artifact (7)"]
["low bq, low freq, many artifacts","UPN_Tr2_078",4,106196327,"A","T","TET2","ENST00000380013","missense_variant","Aca/Tca|p.Thr1554Ser/c.4660A>T",1438,23,1477,0.015572105619499,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.054,"Tolerated",30.78,28.22,708,10,728,0.0137362637362637,730,13,749,0.0173564753004005,0.676244634111134,2,2,"Artifact (4)"]
["many samples","UPN_Tr2_014",4,106196515,"C","G","TET2","ENST00000380013","missense_variant","aaC/aaG|p.Asn1616Lys/c.4848C>G",22864,687,23600,0.0291101694915254,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.628,"Tolerated",32.5,31.59,15993,683,16710,0.0408737283064034,6871,4,6890,0.00058055152394775,6.97966031398314E-097,68,68,"Artifact (8)"]
["strandbias, many samples, low freq","UPN_Tr2_022",4,106196515,"C","G","TET2","ENST00000380013","missense_variant","aaC/aaG|p.Asn1616Lys/c.4848C>G",25423,577,26055,0.0221454615236999,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.628,"Tolerated",32.55,31.74,17727,571,18336,0.03114092495637,7696,6,7719,0.000777302759424796,3.18787729503718E-078,68,68,"Artifact (7)"]
["strandbias, many samples, low freq","UPN_Tr2_049",4,106196515,"C","G","TET2","ENST00000380013","missense_variant","aaC/aaG|p.Asn1616Lys/c.4848C>G",21620,242,21934,0.0110330992978937,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.628,"Tolerated",31.72,30.36,14699,225,14971,0.0150290561752722,6921,17,6963,0.00244147637512566,1.02404326671105E-020,68,68,"Artifact (8)"]
["strandbias, many samples, low freq","UPN_Tr2_058",4,106196515,"C","G","TET2","ENST00000380013","missense_variant","aaC/aaG|p.Asn1616Lys/c.4848C>G",31217,692,32036,0.0216006992133849,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.628,"Tolerated",31.72,30.94,22424,672,23180,0.0289905090595341,8793,20,8856,0.0022583559168925,8.94201116639375E-069,68,68,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_084",4,106196515,"C","G","TET2","ENST00000380013","missense_variant","aaC/aaG|p.Asn1616Lys/c.4848C>G",72567,746,73539,0.0101442771862549,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.628,"Tolerated",31.52,29.58,41046,663,41856,0.0158400229357798,31521,83,31683,0.00261970141716378,4.66455780743216E-082,68,68,"Artifact (9)"]
["low freq, many artifacts","UPN_Tr2_029",4,106196819,"G","T","TET2","ENST00000380013","missense_variant","Gta/Tta|p.Val1718Leu/c.5152G>T",24605,305,24954,0.0122224894,0,0,0,0,1,1,0,0,2,0.66,"NO","COSM41742","haematopoietic_and_lymphoid_tissue",11,"NO","rs142312318","NO",0.002662,"NO","NO",-0.339,"Tolerated",35.43,35.27,13468,302,13805,0.0218761318,11137,3,11149,0.0002690824,2,7,7,"Artifact (11)"]
["many samples, low freq, many artifacts","UPN_Tr2_017",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",10121,385,10509,0.036635265010943,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",35.38,35.79,3939,378,4318,0.0875405280222325,6182,7,6191,0.00113067355839121,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_042",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",25540,610,26171,0.0233082419471935,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",35.2,35.7,7694,562,8268,0.0679729075955491,17846,48,17903,0.00268111489694465,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_035",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",40492,1158,41662,0.0277951130526619,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",35.37,35.85,15102,1122,16232,0.0691227205519961,25390,36,25430,0.00141565080613449,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_090",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",14765,678,15456,0.0438664596273292,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",35.43,35.74,6663,672,7342,0.0915281939526015,8102,6,8114,0.000739462657135815,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_066",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",30423,5565,36012,0.154531822725758,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",34.89,35.72,17105,5542,22661,0.244561140285071,13318,23,13351,0.00172271739944573,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_083",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",28724,2252,31002,0.0726404748080769,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",34.94,35.71,13665,2230,15913,0.140136994909822,15059,22,15089,0.00145801577307973,2,107,107,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_104",4,106196967,"G","A","TET2","ENST00000380013","missense_variant","aGt/aAt|p.Ser1767Asn/c.5300G>A",20344,1573,21929,0.0717314971042911,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","rs185223849","NO",3.931E-005,"NO","NO",-0.699,"Tolerated",35.42,35.93,7940,1559,9505,0.164018937401368,12404,14,12424,0.00112685125563426,2,107,107,"Artifact (4)"]
["low freq","UPN_Tr2_020",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",13176,614,13813,0.0444508796,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.49,35.72,5704,14,5728,0.0024441341,7472,600,8085,0.0742115028,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_005",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",5246,186,5444,0.0341660544,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.38,35.51,2384,2,2393,0.000835771,2862,184,3051,0.0603080957,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_054",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",24424,804,25319,0.0317548086,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.31,35.55,11048,37,11137,0.0033222591,13376,767,14182,0.05408264,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_009",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",41356,1603,43035,0.037248751,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.33,35.56,18311,53,18391,0.0028818444,23045,1550,24644,0.0628956338,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_078",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",23627,767,24439,0.0313842629,0,0,0,0,1,1,0,1,3,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.17,35.4,11137,59,11213,0.0052617498,12490,708,13226,0.0535309239,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_082",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",33852,1031,34967,0.0294849429,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.15,35.47,19784,42,19877,0.0021129949,14068,989,15090,0.0655400928,2,108,108,"Artifact (10)"]
["low freq","UPN_Tr2_100",4,106197000,"A","G","TET2","ENST00000380013","missense_variant","cAt/cGt|p.His1778Arg/c.5333A>G",16552,1041,17619,0.0590839435,0,0,0,0,1,1,0,0,2,3.017,"NO","NO","NO","O","rs62621450","rs62621450","NO",0.045,"NO","YES",-1.986,"Tolerated",35.4,35.7,8037,18,8066,0.0022315894,8515,1023,9553,0.107086779,2,108,108,"Artifact (10)"]
["low freq, many artifacts","UPN_Tr2_048",4,106197098,"T","A","TET2","ENST00000380013","missense_variant","Tgt/Agt|p.Cys1811Ser/c.5431T>A",3112,33,3158,0.0104496516782774,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.658,"Tolerated",34.72,33.76,0,0,0,"NA",3112,33,3158,0.0104496516782774,1,1,1,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_006",4,106197147,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1827Arg/c.5480A>G",7293,94,7400,0.0127027027027027,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.511,"Tolerated",34.61,35.4,2476,18,2494,0.00721732157177225,4817,76,4906,0.0154912352221769,2,8,8,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_003",4,106197443,"C","G","TET2","ENST00000380013","missense_variant","Cgt/Ggt|p.Arg1926Gly/c.5776C>G",3477,65,3556,0.0182789651293588,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.287,"Deleterious",34.13,31.83,738,65,803,0.0809464508094645,2739,0,2753,0,1.60550936096763E-043,77,77,"Artifact (9)"]
["many samples, low freq, many artifacts","UPN_Tr2_029",4,106197443,"C","G","TET2","ENST00000380013","missense_variant","Cgt/Ggt|p.Arg1926Gly/c.5776C>G",20043,384,20489,0.0187417638732979,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.287,"Deleterious",34.17,31.29,5482,379,5877,0.0644886847030798,14561,5,14612,0.000342184505885573,5.49319628182282E-200,77,77,"Artifact (8)"]
["many samples, low freq, many artifacts","UPN_Tr2_058",4,106197443,"C","G","TET2","ENST00000380013","missense_variant","Cgt/Ggt|p.Arg1926Gly/c.5776C>G",28019,430,28560,0.0150560224089636,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.287,"Deleterious",33.53,31.16,8896,423,9347,0.0452551620840912,19123,7,19213,0.000364336647061885,4.69019073048335E-195,77,77,"Artifact (8)"]
["many samples","UPN_Tr2_064",4,106197443,"C","G","TET2","ENST00000380013","missense_variant","Cgt/Ggt|p.Arg1926Gly/c.5776C>G",11798,345,12175,0.0283367556468172,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.287,"Deleterious",33.64,30.86,3070,336,3416,0.0983606557377049,8728,9,8759,0.00102751455645622,1.47814050498872E-175,77,77,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_088",4,106197443,"C","G","TET2","ENST00000380013","missense_variant","Cgt/Ggt|p.Arg1926Gly/c.5776C>G",14882,335,15284,0.021918345982727,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.287,"Deleterious",33.68,31.15,3684,323,4020,0.0803482587064677,11198,12,11264,0.00106534090909091,3.77308534814809E-172,77,77,"Artifact (6)"]
["many samples, low freq, many artifacts","UPN_Tr2_021",4,106197468,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1934Arg/c.5801A>G",14822,168,15024,0.0111821086261981,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.136,"Tolerated",35.35,35.22,5313,80,5404,0.0148038490007402,9509,88,9620,0.00914760914760915,2,55,55,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_049",4,106197468,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1934Arg/c.5801A>G",17906,274,18245,0.0150178130994793,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.136,"Tolerated",35.02,34.95,6015,109,6138,0.0177582274356468,11891,165,12107,0.0136284793920872,2,55,55,"Artifact (5)"]
["many samples, low freq, many artifacts","UPN_Tr2_053",4,106197468,"A","G","TET2","ENST00000380013","missense_variant","aAg/aGg|p.Lys1934Arg/c.5801A>G",30557,396,31048,0.0127544447307395,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.136,"Tolerated",35.03,34.51,9830,135,9990,0.0135135135135135,20727,261,21058,0.0123943394434419,2,55,55,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_002",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",15438,2790,18271,0.152701001587215,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.6,31.65,4353,9,4386,0.00205198358413133,11085,2781,13885,0.200288080662586,2,111,111,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_024",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",9252,859,10133,0.0847725254120201,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.85,31.64,2927,6,2944,0.00203804347826087,6325,853,7189,0.118653498400334,2,111,111,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_031",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",12890,1231,14160,0.0869350282485876,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.99,31.64,4688,10,4721,0.00211819529760644,8202,1221,9439,0.129356923402903,2,111,111,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_054",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",20753,939,21759,0.0431545567351441,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.73,31.54,7634,15,7702,0.00194754609192418,13119,924,14057,0.0657323753290176,2,111,111,"Artifact (5)"]
["many samples, strandbias","UPN_Tr2_060",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",11142,1458,12630,0.115439429928741,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.51,31.6,3268,5,3290,0.00151975683890578,7874,1453,9340,0.155567451820128,2,111,111,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_074",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",7649,1185,8867,0.133641592421338,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.47,31.56,2026,7,2041,0.0034296913277805,5623,1178,6826,0.172575446820979,2,111,111,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_088",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",13570,1884,15502,0.12153270545736,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.6,31.49,4286,7,4308,0.00162488393686165,9284,1877,11194,0.16767911381097,2,111,111,"Artifact (4)"]
["many samples, strandbias","UPN_Tr2_111",4,106197497,"T","C","TET2","ENST00000380013","missense_variant","Tcc/Ccc|p.Ser1944Pro/c.5830T>C",17896,623,18542,0.0335993959659152,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.799,"Tolerated",32.84,31.61,5982,13,6010,0.0021630615640599,11914,610,12532,0.0486753909990425,2,111,111,"Artifact (5)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_041",7,148504750,"C","T","EZH2","ENST00000320356","missense_variant","atG/atA|p.Met748Ile/c.2244G>A",1219,21,1251,0.0167865707434053,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.422,"Tolerated",29.43,32.19,1219,21,1251,0.0167865707434053,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_032",7,148504754,"T","A","EZH2","ENST00000320356","missense_variant","gAa/gTa|p.Glu747Val/c.2240A>T",3427,38,3475,0.0109352517985612,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.04,"Deleterious",23.76,16.89,3427,38,3475,0.0109352517985612,0,0,0,"NA",1,24,24,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_017",7,148504759,"T","A","EZH2","ENST00000320356","missense_variant","gaA/gaT|p.Glu745Asp/c.2235A>T",3242,93,3348,0.0277777777777778,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.388,"Tolerated",20.36,15.3,3242,93,3348,0.0277777777777778,0,0,0,"NA",1,15,15,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_014",7,148504760,"T","A","EZH2","ENST00000320356","missense_variant","gAa/gTa|p.Glu745Val/c.2234A>T",8338,175,8534,0.0205062104523084,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.44,"Deleterious",18.64,16.68,8338,175,8534,0.0205062104523084,0,0,0,"NA",1,52,52,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_027",7,148504760,"T","A","EZH2","ENST00000320356","missense_variant","gAa/gTa|p.Glu745Val/c.2234A>T",11139,259,11430,0.0226596675415573,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.44,"Deleterious",18.62,15.75,11139,259,11430,0.0226596675415573,0,0,0,"NA",1,52,52,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_051",7,148504760,"T","A","EZH2","ENST00000320356","missense_variant","gAa/gTa|p.Glu745Val/c.2234A>T",8091,143,8252,0.017329132331556,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.44,"Deleterious",20.45,15.82,8091,143,8252,0.017329132331556,0,0,0,"NA",1,52,52,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_057",7,148504760,"T","A","EZH2","ENST00000320356","missense_variant","gAa/gTa|p.Glu745Val/c.2234A>T",8381,162,8568,0.0189075630252101,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-5.44,"Deleterious",20.95,16.05,8381,162,8568,0.0189075630252101,0,0,0,"NA",1,52,52,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_030",7,148504775,"T","A","EZH2","ENST00000320356","missense_variant","aAg/aTg|p.Lys740Met/c.2219A>T",8217,335,8577,0.0390579456686487,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.725,"Deleterious",20.88,15.16,8217,335,8577,0.0390579456686487,0,0,0,"NA",1,9,9,"Artifact (3)"]
["low bq, bad alignment, many samples","UPN_Tr2_024",7,148504776,"T","A","EZH2","ENST00000320356","stop_gained","Aag/Tag|p.Lys740*/c.2218A>T",2987,116,3117,0.0372152710940006,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.56,15.07,2987,116,3117,0.0372152710940006,0,0,0,"NA",1,40,40,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_043",7,148504776,"T","A","EZH2","ENST00000320356","stop_gained","Aag/Tag|p.Lys740*/c.2218A>T",6538,184,6743,0.0272875574670028,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.85,17.28,6538,184,6743,0.0272875574670028,0,0,0,"NA",1,40,40,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_050",7,148504781,"G","T","EZH2","ENST00000320356","missense_variant","gCc/gAc|p.Ala738Asp/c.2213C>A",7609,101,7786,0.0129720010274852,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.893,"Tolerated",19.31,15.21,7609,101,7786,0.0129720010274852,0,0,0,"NA",1,2,2,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_017",7,148504790,"T","A","EZH2","ENST00000320356","missense_variant","cAg/cTg|p.Gln735Leu/c.2204A>T",3210,105,3328,0.0315504807692308,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.98,"Deleterious",20.61,15.05,3210,105,3328,0.0315504807692308,0,0,0,"NA",1,32,32,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_057",7,148504790,"T","A","EZH2","ENST00000320356","missense_variant","cAg/cTg|p.Gln735Leu/c.2204A>T",8240,233,8513,0.0273699048514037,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.98,"Deleterious",21.95,15.39,8240,233,8513,0.0273699048514037,0,0,0,"NA",1,32,32,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_020",7,148504794,"T","A","EZH2","ENST00000320356","missense_variant","Agc/Tgc|p.Ser734Cys/c.2200A>T",3611,115,3744,0.030715811965812,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.941,"Deleterious",19.64,15.02,3601,115,3734,0.0307980717728977,10,0,10,0,1,13,13,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_056",7,148506417,"T","C","EZH2","ENST00000320356","missense_variant","Aac/Gac|p.Asn699Asp/c.2095A>G",2375,31,2421,0.0128046261875258,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.167,"Deleterious",33.7,34.87,2375,31,2421,0.0128046261875258,0,0,0,"NA",1,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",7,148508793,"G","T","EZH2","ENST00000320356","missense_variant","tCt/tAt|p.Ser624Tyr/c.1871C>A",4544,67,4621,0.0144990261848085,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.802,"Deleterious",34.07,30.58,2297,30,2334,0.012853470437018,2247,37,2287,0.0161783996501968,0.3896044461812,1,1,"Artifact (2)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_044",7,148512123,"A","G","EZH2","ENST00000320356","missense_variant","Tct/Cct|p.Ser519Pro/c.1555T>C",5513,57,5588,0.0102004294917681,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-3.501,"Deleterious",33.65,32.21,2783,29,2813,0.0103092783505155,2730,28,2775,0.0100900900900901,1,1,1,"Artifact (1)"]
["inspected, many artifacts","UPN_Tr2_072",7,148514358,"A","G","EZH2","ENST00000320356","missense_variant","Ttc/Ctc|p.Phe456Leu/c.1366T>C",3074,32,3107,0.0102993241068555,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.514,"Deleterious",34.9,34.78,3074,32,3107,0.0102993241068555,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, low bq, tolerated effect","UPN_Tr2_049",7,148515044,"C","T","EZH2","ENST00000320356","missense_variant","Gca/Aca|p.Ala389Thr/c.1165G>A",6913,89,7176,0.0124024526198439,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.004,"Tolerated",28.64,23.13,3614,26,3656,0.00711159737417943,3299,63,3520,0.0178977272727273,1.48362141346909E-005,1,1,"Artifact (5)"]
["inspected many artifacts","UPN_Tr2_044",7,148516746,"T","C","EZH2","ENST00000320356","missense_variant","aAg/aGg|p.Lys314Arg/c.941A>G",1816,23,1842,0.0124864277958741,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.204,"Tolerated",34.8,32.65,1816,23,1842,0.0124864277958741,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_016",7,148523602,"A","G","EZH2","ENST00000320356","missense_variant","cTt/cCt|p.Leu284Pro/c.851T>C",16877,185,17151,0.0107865430587138,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.802,"Deleterious",32.93,33.44,8557,95,8663,0.0109661779983839,8320,90,8488,0.0106032045240339,0.882631868618429,20,20,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_044",7,148524256,"T","C","EZH2","ENST00000320356","missense_variant","aAa/aGa|p.Lys243Arg/c.728A>G",1980,32,2015,0.0158808933002481,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.15,"Tolerated",35.21,34.97,1980,32,2015,0.0158808933002481,0,0,0,"NA",1,9,9,"Artifact (6)"]
["many samples, many artifacts","UPN_Tr2_053",7,148524256,"T","C","EZH2","ENST00000320356","missense_variant","aAa/aGa|p.Lys243Arg/c.728A>G",12403,141,12578,0.0112100492924153,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.15,"Tolerated",35.24,33.92,12403,141,12578,0.0112100492924153,0,0,0,"NA",1,9,9,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_056",7,148525958,"TTA","T","EZH2","ENST00000320356","frameshift_variant","ata/|p.Ile166fs/c.497_498delTA",1665,24,1700,0.0141176470588235,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.66,"NA",0,0,0,"NA",1665,24,1700,0.0141176470588235,1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_012",7,148526848,"AT","A","EZH2","ENST00000320356","frameshift_variant","aat/|p.Asn152fs/c.455delA",8672,90,8843,0.0101775415582947,0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.9,"NA",8672,90,8843,0.0101775415582947,0,0,0,"NA",1,2,2,"Artifact (5)"]
["low freq, low bq","UPN_Tr2_090",7,148543650,"G","C","EZH2","ENST00000320356","missense_variant","aCg/aGg|p.Thr53Arg/c.158C>G",5136,54,5323,0.0101446552695848,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO",-2.548,"Deleterious",24.87,25.37,2737,27,2778,0.00971922246220302,2399,27,2545,0.0106090373280943,0.681762903971421,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_056",11,119148929,"A","G","CBL","ENST00000264033","missense_variant","atA/atG|p.Ile383Met/c.1149A>G",1436,24,1465,0.016382252559727,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.802,"Deleterious",32.44,32.88,720,12,734,0.0163487738419619,716,12,731,0.0164158686730506,1,1,1,"Artifact (3)"]
["many samples, low freq, no database","UPN_Tr2_049",11,119148955,"A","G","CBL","ENST00000264033","missense_variant","aAg/aGg|p.Lys392Arg/c.1175A>G",5615,80,5725,0.0139737991266376,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.635,"Tolerated",34.65,34.39,2,0,2,0,5613,80,5723,0.0139786825091735,1,35,35,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_084",11,119148955,"A","G","CBL","ENST00000264033","missense_variant","aAg/aGg|p.Lys392Arg/c.1175A>G",21147,236,21452,0.0110013052396047,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.635,"Tolerated",34.82,34.03,0,0,0,"NA",21147,236,21452,0.0110013052396047,1,35,35,"Artifact (6)"]
["ATG repeat, many samples, low freq","UPN_Tr2_018",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",4884,123,5047,0.0243709134139093,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",34.56,"NA",0,0,0,"NA",4884,123,5047,0.0243709134139093,1,110,110,"Artifact (4)"]
["ATG repeat, many samples, low freq","UPN_Tr2_028",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",6388,158,6594,0.0239611768274189,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",34.32,"NA",4,0,4,0,6384,158,6590,0.0239757207890744,1,110,110,"Artifact (4)"]
["ATG repeat, many samples, low freq","UPN_Tr2_050",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",9436,220,9749,0.0225664170684173,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",33.54,"NA",0,0,0,"NA",9436,220,9749,0.0225664170684173,1,110,110,"Artifact (4)"]
["inspected, ATG repeat, many samples, low freq","UPN_Tr2_056",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",1715,39,1776,0.0219594594594595,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",33.75,"NA",0,0,0,"NA",1715,39,1776,0.0219594594594595,1,110,110,"Artifact (4)"]
["ATG repeat, many samples, low freq","UPN_Tr2_068",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",5870,185,6099,0.0303328414494179,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",34.1,"NA",0,0,0,"NA",5870,185,6099,0.0303328414494179,1,110,110,"Artifact (4)"]
["ATG repeat, many samples, low freq","UPN_Tr2_081",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",5373,185,5599,0.0330416145740311,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",34.22,"NA",0,0,0,"NA",5373,185,5599,0.0330416145740311,1,110,110,"Artifact (4)"]
["ATG repeat, many samples, low freq","UPN_Tr2_106",11,119149355,"TATG","T","CBL","ENST00000264033","disruptive_inframe_deletion","gatgaa/gaa|p.Asp460del/c.1380_1382delTGA",5926,201,6154,0.0326616834579136,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-3.45,"Deleterious",34.99,"NA",0,0,0,"NA",5926,201,6154,0.0326616834579136,1,110,110,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_026",11,119149358,"G","T","CBL","ENST00000264033","missense_variant","Gat/Tat|p.Asp456Tyr/c.1366G>T",7826,103,7941,0.0129706586072283,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.045,"Deleterious",34.6,29.83,0,0,0,"NA",7826,103,7941,0.0129706586072283,1,24,24,"Artifact (4)"]
["strandbias, many samples","UPN_Tr2_016",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",10690,511,11238,0.0454707243281723,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",33.23,31.58,6003,507,6538,0.0775466503517895,4687,4,4700,0.000851063829787234,8.53026080626099E-116,90,90,"Artifact (7)"]
["many samples","UPN_Tr2_024",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",8142,344,8516,0.0403945514325975,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",33.32,31.57,4533,343,4895,0.0700715015321757,3609,1,3621,0.000276166804750069,2.37221398029226E-083,90,90,"Artifact (8)"]
["strandbias, many samples","UPN_Tr2_049",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",17115,394,17593,0.0223952708463593,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",32.88,30.94,9677,386,10104,0.0382026920031671,7438,8,7489,0.00106823340899987,1.35487196370778E-081,90,90,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_009",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",38920,1857,40912,0.0453901055924912,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",33.26,31.4,19561,1847,21487,0.0859589519244194,19359,10,19425,0.000514800514800515,0,90,90,"Artifact (6)"]
["strandbias, many samples","UPN_Tr2_063",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",18091,1706,19875,0.0858364779874214,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",32.54,31.39,12296,1694,14054,0.120535078981073,5795,12,5821,0.0020615014602302,9.59210848992947E-246,90,90,"Artifact (6)"]
["many samples","UPN_Tr2_071",11,119149376,"C","G","CBL","ENST00000264033","missense_variant","Cga/Gga|p.Arg462Gly/c.1384C>G",11973,1053,13064,0.0806031843233313,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.502,"Tolerated",32.48,31.45,8385,1046,9462,0.110547452969774,3588,7,3602,0.00194336479733481,7.85908843675334E-141,90,90,"Artifact (8)"]
["low freq, many artifacts","UPN_Tr2_081",11,119149414,"TG","T","CBL","ENST00000264033","frameshift_variant","ggt/|p.Gly475fs/c.1424delG",15134,156,15340,0.0101694915254237,0,0,0,1,0,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.82,"NA",9671,29,9735,0.00297894196199281,5463,127,5605,0.0226583407671722,2,1,2,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_044",12,11905462,"C","T","ETV6","ENST00000396373","missense_variant","Cct/Tct|p.Pro38Ser/c.112C>T",1550,54,1607,0.0336029869321718,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.166,"Tolerated",33.99,34.91,1550,54,1607,0.0336029869321718,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_056",12,12006400,"A","T","ETV6","ENST00000396373","missense_variant","cAg/cTg|p.Gln123Leu/c.368A>T",4309,52,4372,0.0118938700823422,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.692,"Deleterious",35.07,32.81,4309,52,4372,0.0118938700823422,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_006",12,12006451,"TAC","T","ETV6","ENST00000396373","frameshift_variant","cag/|p.Gln143fs/c.427_428delCA",17943,248,18274,0.0135711940461858,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.36,"NA",9063,125,9219,0.0135589543334418,8880,123,9055,0.013583655438984,1,14,15,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_050",12,12022501,"T","C","ETV6","ENST00000396373","missense_variant","Tcc/Ccc|p.Ser203Pro/c.607T>C",7371,83,7524,0.0110313662945242,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.082,"Tolerated",25.67,30.51,0,0,0,"NA",7371,83,7524,0.0110313662945242,1,6,11,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_044",12,12022528,"C","T","ETV6","ENST00000396373","missense_variant","Ctc/Ttc|p.Leu212Phe/c.634C>T",2747,51,2806,0.0181753385602281,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.83,"Tolerated",34.64,32.82,0,0,0,"NA",2747,51,2806,0.0181753385602281,1,1,1,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_084",12,12022649,"A","C","ETV6","ENST00000396373","missense_variant","cAc/cCc|p.His252Pro/c.755A>C",4689,1690,6407,0.263773997190573,1,0,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.351,"Tolerated",22.95,16.27,3152,74,3244,0.0228113440197287,1537,1616,3163,0.510907366424281,0,18,18,"Artifact (3)"]
["inspected, many artifacts","UPN_Tr2_076",12,12037473,"C","A","ETV6","ENST00000396373","missense_variant","ttC/ttA|p.Phe368Leu/c.1104C>A",41932,1072,43120,0.024860853432282,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-5.283,"Deleterious",32.01,31.71,21107,583,21716,0.0268465647448886,20825,489,21404,0.0228461969725285,0.00934445074917399,1,1,"Artifact (0)"]
["low freq, many artifacts","UPN_Tr2_047",12,25380186,"T","C","KRAS","ENST00000256078","missense_variant","gAa/gGa|p.Glu91Gly/c.272A>G",6778,70,6866,0.0101951645790853,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.463,"Deleterious",33.76,32.46,3430,36,3476,0.0103567318757192,3348,34,3390,0.0100294985250737,0.904991871318004,1,1,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_022",12,25380274,"C","G","KRAS","ENST00000256078","missense_variant","Gag/Cag|p.Glu62Gln/c.184G>C",10132,116,10278,0.0112862424596225,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.926,"Deleterious",33.66,31.25,4965,114,5092,0.0223880597014925,5167,2,5186,0.000385653682992673,1.83185967395723E-032,59,59,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_008",12,25380274,"C","G","KRAS","ENST00000256078","missense_variant","Gag/Cag|p.Glu62Gln/c.184G>C",24569,267,24871,0.0107353946363234,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.926,"Deleterious",33.69,31.42,11416,264,11701,0.0225621741731476,13153,3,13170,0.000227790432801822,3.15271706140425E-082,59,59,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_070",12,25380274,"C","G","KRAS","ENST00000256078","missense_variant","Gag/Cag|p.Glu62Gln/c.184G>C",14283,201,14499,0.0138630250362094,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.926,"Deleterious",33.44,31.12,6971,194,7174,0.0270420964594369,7312,7,7325,0.000955631399317406,3.1507175665882E-050,59,59,"Artifact (10)"]
["many samples, low freq, no database","UPN_Tr2_088",12,25380274,"C","G","KRAS","ENST00000256078","missense_variant","Gag/Cag|p.Glu62Gln/c.184G>C",19326,242,19599,0.0123475687535078,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.926,"Deleterious",33.55,31.11,8703,233,8956,0.0260160786065208,10623,9,10643,0.000845626233204923,2.93761931393983E-067,59,59,"Artifact (9)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_001",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",11406,155,11568,0.0133990318118949,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.12,"NA",5768,78,5828,0.0133836650652025,5638,77,5740,0.0134146341463415,1,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_026",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",17714,242,17901,0.0135187978325233,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.25,"NA",8952,123,9029,0.0136227710709935,8762,119,8872,0.0134129846708747,0.948453229940188,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_089",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",14521,182,14681,0.0123969756828554,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.59,"NA",7340,93,7385,0.0125930941096818,7181,89,7296,0.0121984649122807,0.940565557767165,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_009",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",34213,490,34646,0.0141430468163713,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.95,"NA",17312,247,17477,0.0141328603307204,16901,243,17169,0.0141534160405382,0.963714594699196,108,220,"Artifact (8)"]
["inspected, many samples, homopolymer 7C, low freq","UPN_Tr2_056",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",11716,166,11926,0.0139191682039242,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.58,"NA",5955,83,6028,0.0137690776376908,5761,83,5898,0.0140725669718549,0.875846946452694,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_062",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",27823,399,28617,0.0139427612957333,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.49,"NA",14326,210,14488,0.0144947542794036,13497,189,14129,0.013376742869276,0.686598165601561,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_082",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",16074,227,16504,0.0137542413960252,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.87,"NA",8285,122,8380,0.0145584725536993,7789,105,8124,0.0129246676514032,0.547390129993986,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_099",15,90631917,"T","TC","IDH2","ENST00000330062","frameshift_variant","ggg/gggG|p.Thr146fs/c.435dupG",6407,83,6502,0.0127653029836973,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.57,"NA",3245,43,3271,0.0131458269642311,3162,40,3231,0.0123800680903745,0.912119476289783,108,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_021",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",11661,186,11908,0.0156197514276117,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",33.43,"NA",5877,93,5995,0.0155129274395329,5784,93,5913,0.0157280568239472,0.941154245520428,111,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_089",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",14389,250,14702,0.0170044891851449,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",33.61,"NA",7239,126,7385,0.0170616113744076,7150,124,7317,0.016946836135028,1,111,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_051",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",21658,373,22190,0.016809373591708,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",33.02,"NA",10973,192,11215,0.0171199286669639,10685,181,10975,0.0164920273348519,0.794031328182481,111,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_011",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",24400,387,24880,0.0155546623794212,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",34.1,"NA",12309,196,12540,0.0156299840510367,12091,191,12340,0.0154781199351702,0.959158483525293,111,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_070",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",14473,211,14771,0.0142847471396656,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",32.63,"NA",7349,107,7478,0.0143086386734421,7124,104,7293,0.0142602495543672,1,111,220,"Artifact (8)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_078",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",21061,338,21511,0.0157128910789828,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",32.75,"NA",10651,170,10853,0.0156638717405326,10410,168,10658,0.0157628072809157,0.956284959961552,111,220,"Artifact (7)"]
["many samples, homopolymer 7C, low freq","UPN_Tr2_108",15,90631917,"TC","T","IDH2","ENST00000330062","frameshift_variant","ggg/|p.Thr146fs/c.435delG",18391,301,18738,0.016063614046323,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",33.62,"NA",9254,150,9418,0.0159269483966872,9137,151,9320,0.0162017167381974,0.907505234864099,111,220,"Artifact (8)"]
["many samples, low freq, no database","UPN_Tr2_018",15,90631953,"T","C","IDH2","ENST00000330062","missense_variant","Agt/Ggt|p.Ser134Gly/c.400A>G",5578,67,5653,0.0118521139218114,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.749,"Deleterious",34.91,34.84,0,0,0,"NA",5578,67,5653,0.0118521139218114,1,15,15,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_021",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",3425,40,3507,0.0114057599087539,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.44,"NA",3425,40,3507,0.0114057599087539,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_026",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",5028,63,5162,0.0122045718713677,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.39,"NA",5028,63,5162,0.0122045718713677,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_033",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",3274,50,3366,0.0148544266191325,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.46,"NA",3274,50,3366,0.0148544266191325,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_057",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",5673,74,5824,0.012706043956044,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.07,"NA",5673,74,5824,0.012706043956044,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_066",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",2708,42,2787,0.0150699677072121,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.31,"NA",2708,42,2787,0.0150699677072121,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_079",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",2296,38,2371,0.0160269928300295,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.45,"NA",2296,38,2371,0.0160269928300295,0,0,0,"NA",1,99,99,"Artifact (10)"]
["low freq, many artifacts, many samples","UPN_Tr2_104",17,7572962,"GT","G","TP53","ENST00000269305","frameshift_variant","aaa/|p.Lys382fs/c.1141delA",4851,76,4966,0.0153040676600886,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.46,"NA",4851,76,4966,0.0153040676600886,0,0,0,"NA",1,99,99,"Artifact (10)"]
["inspected, many artifacts","UPN_Tr2_012",17,7572994,"T","C","TP53","ENST00000269305","missense_variant","aAa/aGa|p.Lys372Arg/c.1115A>G",3821,46,3880,0.0118556701030928,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.104,"Tolerated",34.25,32.57,1922,23,1954,0.0117707267144319,1899,23,1926,0.0119418483904465,1,1,1,"Artifact (4)"]
["inspected, bad alignment, many artifacts","UPN_Tr2_056",17,7577030,"C","T","TP53","ENST00000269305","missense_variant","aGc/aAc|p.Ser303Asn/c.908G>A",1983,45,2033,0.0221347761928185,0,0,0,0,1,1,0,1,3,"NO","NO","COSM43986","breast, large_intestine, urinary_tract","1, 1, 1","NO","NO","NO","NO","NO","NO",-0.19,"Tolerated",31.19,32.51,1007,24,1034,0.02321083172147,976,21,999,0.021021021021021,0.764901290082912,1,1,"Artifact (1)"]
["low freq, many artifacts, many samples","UPN_Tr2_006",17,7577575,"A","T","TP53","ENST00000269305","missense_variant","Tac/Aac|p.Tyr236Asn/c.706T>A",17676,180,17894,0.0100592377333184,0,0,0,0,1,0,0,0,1,"NO","NO","COSM1644276, COSM1157852, COSM1157851, COSM43826, COSM3388353","haematopoietic_and_lymphoid_tissue, pancreas, skin, breast, central_nervous_system, oesophagus, stomach, upper_aerodigestive_tract","7, 13, 7, 1, 1, 2, 1, 4","NO","NO","NO","NO","NO","NO",-6.548,"Deleterious",34.03,27.12,8911,61,8988,0.00678682688028482,8765,119,8906,0.0133617785762407,1.17883456222473E-005,1,1,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_020",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",5549,344,5925,0.0580590717299578,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.75,31.66,3367,12,3407,0.00352216025829175,2182,332,2518,0.131850675138999,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_029",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",10624,600,11265,0.0532623169107856,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.77,31.56,6760,20,6816,0.00293427230046948,3864,580,4449,0.130366374466172,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_050",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",17509,375,17989,0.0208460725999222,0,0,0,0,1,1,0,1,3,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.41,31.91,10583,40,10711,0.00373447857342919,6926,335,7278,0.0460291288815609,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_059",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",10135,913,11101,0.0822448428069543,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.22,31.39,4551,7,4594,0.00152372659991293,5584,906,6507,0.139234670355002,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_067",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",8452,875,9360,0.093482905982906,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.15,31.65,3674,7,3703,0.00189035916824197,4778,868,5657,0.153438218136822,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_086",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",4745,532,5295,0.100472143531634,0,1,0,0,1,1,0,0,3,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.06,31.4,2022,8,2040,0.00392156862745098,2723,524,3255,0.160983102918587,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_104",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",9183,248,9454,0.0262322826316903,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.8,31.77,5250,7,5273,0.00132751754219609,3933,241,4181,0.0576417125089691,2,111,111,"Artifact (2)"]
["low freq, many samples, no database, strandbias","UPN_Tr2_108",17,7578394,"T","C","TP53","ENST00000269305","missense_variant","cAt/cGt|p.His179Arg/c.536A>G",13308,278,13614,0.0204201557220508,0,0,0,0,1,1,0,0,2,"NO","NO","COSM214222, COSM10889, COSM1645241, COSM214223, COSM3396280","biliary_tract, breast, central_nervous_system, endometrium, haematopoietic_and_lymphoid_tissue, large_intestine, lung, oesophagus, ovary, pancreas, prostate, stomach, upper_aerodigestive_tract, cervix, liver, urinary_tract","11, 38, 66, 6, 13, 32, 20, 41, 26, 18, 11, 15, 17, 1, 1, 4","NO","NO","NO","NO","NO","NO",-7.562,"Deleterious",33.78,31.92,7350,22,7394,0.00297538544766027,5958,256,6220,0.0411575562700965,2,111,111,"Artifact (2)"]
["low bq, many samples, no database","UPN_Tr2_058",17,7578502,"A","T","TP53","ENST00000269305","missense_variant","gTg/gAg|p.Val143Glu/c.428T>A",12884,169,13109,0.0128919063238996,0,0,0,0,1,0,0,1,2,"NO","NO","COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1","NO","NO","NO","NO","NO","NO",-5.68,"Deleterious",32.21,25.67,0,51,51,1,12884,118,13058,0.00903660591208455,1.26158444691236E-100,45,45,"Artifact (3)"]
["low bq, many samples, no database","UPN_Tr2_091",17,7578502,"A","T","TP53","ENST00000269305","missense_variant","gTg/gAg|p.Val143Glu/c.428T>A",4470,54,4544,0.0118838028169014,0,0,0,0,1,0,0,1,2,"NO","NO","COSM3522708, COSM3522705, COSM45382, COSM3522707, COSM3522706","oesophagus, skin, breast, large_intestine, lung, upper_aerodigestive_tract, urinary_tract","5, 5, 1, 1, 1, 1, 1","NO","NO","NO","NO","NO","NO",-5.68,"Deleterious",32.73,27.04,0,22,22,1,4470,32,4522,0.0070765148164529,3.49832282647568E-045,45,45,"Artifact (3)"]
["inspected","UPN_Tr2_074",17,7579384,"TTTCTGGGAAGGGACAGAAGATGACAGGGGCCAGGAGGGGGCTGGTGCAGGGGCCGCCGGTGTAGGAGCTGCTGGTGCAGGGGCCACGGGGGGAGCAGCCTCTGGCA","T","TP53","ENST00000269305","frameshift_variant","|p.Met66fs/c.197_302del",180,"NA",186,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.46,"NA",173,"NA",179,"NA",7,"NA",7,"NA","NA",3,3,"Artifact (3)"]
["low freq, low bq, tolerated prediction","UPN_Tr2_078",17,7579425,"C","T","TP53","ENST00000269305","missense_variant","Gcc/Acc|p.Ala88Thr/c.262G>A",2499,27,2558,0.0105551211884285,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.487,"Tolerated",28.94,25,1273,12,1287,0.00932400932400932,1226,15,1271,0.011801730920535,0.56428664757562,1,1,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_018",17,7579548,"G","C","TP53","ENST00000269305","missense_variant","Ccg/Gcg|p.Pro47Ala/c.139C>G",7038,150,7213,0.0207957853874948,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",33.23,30.37,4538,11,4561,0.00241175180881386,2500,139,2652,0.0524132730015083,2,68,68,"Artifact (7)"]
["many samples, low freq, no database","UPN_Tr2_024",17,7579548,"G","C","TP53","ENST00000269305","missense_variant","Ccg/Gcg|p.Pro47Ala/c.139C>G",5586,71,5673,0.0125154239379517,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",33.61,31.68,4123,1,4134,0.000241896468311563,1463,70,1539,0.0454840805717999,2,68,68,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_010",17,7579548,"G","C","TP53","ENST00000269305","missense_variant","Ccg/Gcg|p.Pro47Ala/c.139C>G",13226,268,13528,0.0198107628622117,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",33.27,30.61,9664,12,9698,0.00123736852959373,3562,256,3830,0.0668407310704961,2,68,68,"Artifact (9)"]
["many samples","UPN_Tr2_062",17,7579548,"G","C","TP53","ENST00000269305","missense_variant","Ccg/Gcg|p.Pro47Ala/c.139C>G",7739,192,7969,0.0240933617768854,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.02,"Tolerated",32.73,29.61,5844,18,5897,0.0030523995251823,1895,174,2072,0.083976833976834,2,68,68,"Artifact (7)"]
["inspected, many artifacts","UPN_Tr2_097",17,7579575,"G","C","TP53","ENST00000269305","missense_variant","Caa/Gaa|p.Gln38Glu/c.112C>G",7570,173,7771,0.0222622571,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.115,"Tolerated",33.9,30.88,7570,173,7771,0.0222622571,0,0,0,"NA",1,3,3,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_083",17,7579716,"G","T","TP53","ENST00000269305","missense_variant","cCt/cAt|p.Pro27His/c.80C>A",2960,33,2997,0.011011011011011,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.615,"Tolerated",34.01,31.24,859,31,891,0.0347923681257015,2101,2,2106,0.000949667616334283,2,8,8,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_052",17,7579849,"G","T","TP53","ENST00000269305","missense_variant","Cta/Ata|p.Leu22Ile/c.64C>A",3973,55,4043,0.013603759584467,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.219,"Tolerated",32.51,29.38,2017,24,2050,0.0117073170731707,1956,31,1993,0.0155544405418966,0.342241033709867,1,1,"Artifact (4)"]
["homopolymer 6G, low freq, many samples","UPN_Tr2_030",17,74732955,"CG","C","SRSF2","ENST00000392485","frameshift_variant","ccg/|p.Pro96fs/c.287delC",5880,87,5989,0.0145266321589581,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.14,"NA",2956,45,3012,0.0149402390438247,2924,42,2977,0.0141081625797783,0.829393557419905,23,30,"Artifact (2)"]
["homopolymer 6G, low freq, many samples","UPN_Tr2_050",17,74732955,"CG","C","SRSF2","ENST00000392485","frameshift_variant","ccg/|p.Pro96fs/c.287delC",7064,89,7184,0.0123886414253898,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.38,"NA",3560,46,3622,0.0127001656543346,3504,43,3562,0.0120718697361033,0.831727029152404,23,30,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_009",17,74733032,"C","G","SRSF2","ENST00000392485","missense_variant","Gct/Cct|p.Ala71Pro/c.211G>C",4077,61,4146,0.0147129763627593,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.237,"Deleterious",35.45,31.52,4,60,64,0.9375,4073,1,4082,0.000244977951984321,4.86799701330747E-128,11,11,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_058",17,74733032,"C","G","SRSF2","ENST00000392485","missense_variant","Gct/Cct|p.Ala71Pro/c.211G>C",3009,50,3065,0.0163132137030995,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.237,"Deleterious",34.98,30.2,1,47,48,0.979166666666667,3008,3,3017,0.000994365263506795,5.22109721697901E-099,11,11,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_015",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",13080,317,13546,0.023401742211723,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",34.94,35.16,9070,311,9514,0.0326886693294093,4010,6,4032,0.00148809523809524,2,92,93,"Artifact (4)"]
["many samples, low freq, no database","UPN_Tr2_042",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",20571,422,21296,0.0198159278737791,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",34.56,34.82,14853,416,15531,0.0267851393986221,5718,6,5765,0.001040763226366,2,92,93,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_035",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",8779,154,9045,0.0170259812050857,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",35.12,35.54,6434,154,6694,0.0230056767254258,2345,0,2351,0,2,92,93,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_055",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",18141,342,18725,0.0182643524699599,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",34.48,34.85,12881,338,13437,0.0251544243506735,5260,4,5288,0.00075642965204236,2,92,93,"Artifact (7)"]
["many samples","UPN_Tr2_076",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",905,23,940,0.024468085106383,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",35.14,35.04,751,23,786,0.0292620865139949,154,0,154,0,2,92,93,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_104",17,74733043,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp67Ala/c.200A>C",6535,107,6687,0.0160011963511291,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.809,"Deleterious",35.4,35.43,4838,107,4986,0.0214600882470919,1697,0,1701,0,2,92,93,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_081",17,74733079,"CG","C","SRSF2","ENST00000392485","frameshift_variant","cgc/|p.Arg55fs/c.163delC",3021,40,3071,0.0130250732660371,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.96,"NA",2345,0,2351,0,676,40,720,0.0555555555555556,2,2,2,"Artifact (3)"]
["many samples, lower bq, no database","UPN_Tr2_004",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",2287,31,2327,0.0133218736570692,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.84,32.16,2153,4,2166,0.00184672206832872,134,27,161,0.167701863354037,2,99,99,"Artifact (6)"]
["many samples, lower bq, no database","UPN_Tr2_033",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",7073,317,7415,0.0427511800404585,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.34,31.56,5142,10,5165,0.00193610842207164,1931,307,2250,0.136444444444444,2,99,99,"Artifact (4)"]
["many samples, lower bq, no database","UPN_Tr2_010",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",11903,382,12331,0.0309788338334279,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.63,31.81,10345,27,10413,0.00259291270527226,1558,355,1918,0.185088633993743,2,99,99,"Artifact (4)"]
["many samples, lower bq, no database","UPN_Tr2_093",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",3501,37,3544,0.0104401805869075,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.67,31.84,2709,3,2717,0.00110415899889584,792,34,827,0.0411124546553809,2,99,99,"Artifact (6)"]
["many samples, lower bq, no database","UPN_Tr2_095",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",6719,134,6861,0.0195306806587961,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.41,32.37,5031,27,5064,0.00533175355450237,1688,107,1797,0.0595436839176405,2,99,99,"Artifact (6)"]
["many samples, lower bq, no database","UPN_Tr2_107",17,74733085,"T","C","SRSF2","ENST00000392485","missense_variant","gAg/gGg|p.Glu53Gly/c.158A>G",10466,134,10620,0.0126177024482109,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-6.093,"Deleterious",34.5,31.91,7776,15,7808,0.00192110655737705,2690,119,2812,0.0423186344238976,2,99,99,"Artifact (6)"]
["low bq, bad alignment, many samples","UPN_Tr2_070",17,74733203,"T","G","SRSF2","ENST00000392485","missense_variant","Acc/Ccc|p.Thr14Pro/c.40A>C",246,30,276,0.108695652173913,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.673,"Deleterious",19.54,15.27,0,0,0,"NA",246,30,276,0.108695652173913,1,12,12,"Artifact (2)"]
["inspected, many samples, homopolymer 6G, ins and del","UPN_Tr2_036",17,74733222,"A","AG","SRSF2","ENST00000392485","frameshift_variant","cct/ccCt|p.Pro8fs/c.20dupC",5521,140,5568,0.0251436781609195,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.2,"NA",0,0,0,"NA",5521,140,5568,0.0251436781609195,1,4,7,"Artifact (3)"]
["low bq, many samples, no database","UPN_Tr2_070",19,33792364,"A","C","CEBPA","ENST00000498907","missense_variant","agT/agG|p.Ser319Arg/c.957T>G",3508,1842,5379,0.342442833240379,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.005,"Deleterious",27.15,20.85,823,1828,2662,0.686701728024042,2685,14,2717,0.00515274199484726,0,30,30,"Artifact (1)"]
["low bq, many samples, no database","UPN_Tr2_079",19,33792364,"A","C","CEBPA","ENST00000498907","missense_variant","agT/agG|p.Ser319Arg/c.957T>G",4239,2128,6423,0.331309356998287,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.005,"Deleterious",27.18,20.82,1052,2115,3190,0.663009404388715,3187,13,3233,0.00402103309619548,0,30,30,"Artifact (1)"]
["low bq, many samples, no database","UPN_Tr2_087",19,33792364,"A","C","CEBPA","ENST00000498907","missense_variant","agT/agG|p.Ser319Arg/c.957T>G",6180,3065,9300,0.329569892473118,1,1,0,0,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.005,"Deleterious",27.14,20.71,1549,3038,4606,0.659574468085106,4631,27,4694,0.00575202386024712,0,30,30,"Artifact (1)"]
["many samples, neutral effect, low freq","UPN_Tr2_027",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",9647,2007,11678,0.171861620140435,0,1,0,1,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.37,31.63,28,0,28,0,9619,2007,11650,0.172274678111588,2,111,111,"Artifact (5)"]
["many samples, neutral effect, low freq","UPN_Tr2_005",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",1942,627,2579,0.243117487398216,0,1,0,1,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.1,31.72,0,0,0,"NA",1942,627,2579,0.243117487398216,2,111,111,"Artifact (5)"]
["many samples, neutral effect, low freq","UPN_Tr2_010",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",10031,2521,12580,0.200397456279809,0,1,0,1,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.24,31.56,2,0,2,0,10029,2521,12578,0.200429321036731,2,111,111,"Artifact (5)"]
["many samples, neutral effect, low freq","UPN_Tr2_040",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",3721,617,4351,0.141806481268674,0,1,0,1,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.44,31.72,4,0,4,0,3717,617,4347,0.141936968023925,2,111,111,"Artifact (5)"]
["many samples, neutral effect, low freq","UPN_Tr2_077",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",3869,749,4627,0.161875945537065,0,1,0,1,1,0,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.03,31.72,0,0,0,"NA",3869,749,4627,0.161875945537065,2,111,111,"Artifact (5)"]
["many samples","UPN_Tr2_094",19,33792480,"T","C","CEBPA","ENST00000498907","missense_variant","Aac/Gac|p.Asn281Asp/c.841A>G",8430,460,8912,0.0516157989228007,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.096,"Tolerated",31.47,31.69,10,0,10,0,8420,460,8902,0.0516737811727702,2,111,111,"Artifact (7)"]
["many samples","UPN_Tr2_055",19,33792507,"CCGCGCCGCTGCCGCCACTCGCGCGGAGGTCGGGGTGCGCGGCGCCCAGCCCCTTGAGCGCGCTGCCAGGGCCCGGCAGGCCGGCGGCACCGAGCGCGGG","C","CEBPA","ENST00000498907","inframe_deletion","cccgcgctcggtgccgccggcctgccgggccctggcagcgcgctcaaggggctgggcgccgcgcaccccgacctccgcgcgagtggcggcagcggcgcg/|p.Pro239_Ala271del/c.715_813delCCCGCGCTCGGTGCCGCCGGCCTGCCGGGCCCTGGCAGCGCGCTCAAGGGGCTGGGCGCCGCGCACCCCGACCTCCGCGCGAGTGGCGGCAGCGGCGCG",107,"NA",107,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-22.439,"Deleterious",33.17,"NA",107,"NA",107,"NA",0,"NA",0,"NA","NA",4,4,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_041",19,33792669,"T","A","CEBPA","ENST00000498907","missense_variant","Atg/Ttg|p.Met218Leu/c.652A>T",1131,27,1160,0.0232758620689655,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.245,"Tolerated",35.22,35.19,550,2,553,0.00361663652802893,581,25,607,0.0411861614497529,2,1,1,"Artifact (1)"]
["many samples, GGC repeat","UPN_Tr2_037",19,33792754,"GGGC","G","CEBPA","ENST00000498907","disruptive_inframe_deletion","ccgccc/ccc|p.Pro189del/c.564_566delGCC",480,20,500,0.04,0,0,0,1,0,0,0,1,2,3.0928,"NO","NO","NA","NA","NO","NO","NO","NA","NO","NO",-0.265,"Tolerated",34.53,"NA",244,10,254,0.0393700787,236,10,246,0.0406504065,1,26,26,"Artifact (11)"]
["inspected, many artifacts, strandbias","UPN_Tr2_044",19,33792847,"CA","C","CEBPA","ENST00000498907","frameshift_variant","ctg/|p.Leu158fs/c.473delT",447,26,474,0.0548523206751055,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.72,"NA",220,0,221,0,227,26,253,0.102766798418972,2,1,1,"Artifact (0)"]
["many samples, no database","UPN_Tr2_038",19,33792863,"G","C","CEBPA","ENST00000498907","missense_variant","cCg/cGg|p.Pro153Arg/c.458C>G",454,54,508,0.106299212598425,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.747,"Tolerated",32.03,31.59,39,0,39,0,415,54,469,0.115138592750533,2,21,21,"Artifact (1)"]
["inspected, CGC repeat, many samples","UPN_Tr2_052",19,33793007,"TCGC","T","CEBPA","ENST00000498907","disruptive_inframe_deletion","ggcgac/gac|p.Gly104del/c.311_313delGCG",1028,20,1053,0.0189933523,0,0,0,1,0,0,0,1,2,0.1827,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",0.146,"Tolerated",35.19,"NA",0,0,0,"NA",1028,20,1053,0.0189933523,1,3,3,"Artifact (11)"]
["many samples, homopolymer 6C, low freq","UPN_Tr2_047",19,33793252,"CG","C","CEBPA","ENST00000498907","frameshift_variant","ccg/|p.Pro23fs/c.68delC",2061,28,2097,0.0133524082021936,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.16,"NA",24,0,24,0,2037,28,2073,0.0135069946936807,1,6,8,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_023",19,33793288,"CG","C","CEBPA","ENST00000498907","frameshift_variant","ccg/|p.Pro11fs/c.32delC",2496,30,2529,0.0118623962040332,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.24,"NA",1222,0,1224,0,1274,30,1305,0.0229885057471264,2,53,53,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_036",19,33793288,"CG","C","CEBPA","ENST00000498907","frameshift_variant","ccg/|p.Pro11fs/c.32delC",2968,38,3015,0.0126036484245439,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.39,"NA",1415,0,1417,0,1553,38,1598,0.0237797246558198,2,53,53,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_050",19,33793288,"CG","C","CEBPA","ENST00000498907","frameshift_variant","ccg/|p.Pro11fs/c.32delC",2548,45,2608,0.0172546012269939,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.99,"NA",1180,0,1190,0,1368,45,1418,0.0317348377997179,2,53,53,"Artifact (5)"]
["many samples, GC region","UPN_Tr2_094",19,33793288,"CG","C","CEBPA","ENST00000498907","frameshift_variant","ccg/|p.Pro11fs/c.32delC",759,33,795,0.0415094339622641,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.52,"NA",32,0,32,0,727,33,763,0.0432503276539974,2,53,53,"Artifact (1)"]
["low freq, many artifacts","UPN_Tr2_036",19,33793292,"TC","T","CEBPA","ENST00000498907","frameshift_variant","gag/|p.Glu10fs/c.28delG",2972,34,3015,0.0112769485903814,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.46,"NA",1414,0,1417,0,1558,34,1598,0.0212765957446809,2,1,1,"Artifact (3)"]
["many samples, strandbias","UPN_Tr2_022",19,33793307,"T","C","CEBPA","ENST00000498907","missense_variant","gAc/gGc|p.Asp5Gly/c.14A>G",2018,129,2160,0.0597222222222222,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.083,"Tolerated",32.99,31.59,1214,3,1225,0.00244897959183673,804,126,935,0.13475935828877,2,76,77,"Artifact (6)"]
["many samples, strandbias","UPN_Tr2_033",19,33793307,"T","C","CEBPA","ENST00000498907","missense_variant","gAc/gGc|p.Asp5Gly/c.14A>G",1488,105,1601,0.0655840099937539,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.083,"Tolerated",32.35,31.73,748,5,759,0.00658761528326746,740,100,842,0.118764845605701,2,76,77,"Artifact (6)"]
["inspected, many samples, strandbias","UPN_Tr2_039",19,33793307,"T","C","CEBPA","ENST00000498907","missense_variant","gAc/gGc|p.Asp5Gly/c.14A>G",1383,118,1506,0.0783532536520584,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.083,"Tolerated",32,31.2,666,2,671,0.0029806259314456,717,116,835,0.138922155688623,2,76,77,"Artifact (6)"]
["many samples","UPN_Tr2_096",19,33793307,"T","C","CEBPA","ENST00000498907","missense_variant","gAc/gGc|p.Asp5Gly/c.14A>G",679,34,713,0.0476858345021038,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.083,"Tolerated",30.36,32,31,0,31,0,648,34,682,0.0498533724340176,2,76,77,"Artifact (7)"]
["many samples","UPN_Tr2_109",19,33793307,"T","C","CEBPA","ENST00000498907","missense_variant","gAc/gGc|p.Asp5Gly/c.14A>G",836,52,888,0.0585585585585586,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.083,"Tolerated",31.12,31.31,91,0,91,0,745,52,797,0.0652446675031368,2,76,77,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_045",20,31022323,"C","A","ASXL1","ENST00000375687","missense_variant","tCc/tAc|p.Ser603Tyr/c.1808C>A",13919,180,14173,0.0127002046144077,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.146,"Tolerated",35.46,35.71,2105,0,2108,0,11814,180,12065,0.0149191877331123,2,40,40,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_091",20,31022323,"C","A","ASXL1","ENST00000375687","missense_variant","tCc/tAc|p.Ser603Tyr/c.1808C>A",5581,92,5681,0.0161943319838057,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.146,"Tolerated",35.54,36,797,0,798,0,4784,92,4883,0.018840876510342,2,40,40,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_099",20,31022323,"C","A","ASXL1","ENST00000375687","missense_variant","tCc/tAc|p.Ser603Tyr/c.1808C>A",4097,43,4152,0.0103564547206166,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.146,"Tolerated",35.63,35.65,734,0,734,0,3363,43,3418,0.0125804564072557,2,40,40,"Artifact (6)"]
["many samples, low freq","UPN_Tr2_063",20,31022328,"T","A","ASXL1","ENST00000375687","missense_variant","Tgc/Agc|p.Cys605Ser/c.1813T>A",9042,103,9189,0.0112090543040592,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",1.424,"Tolerated",35.47,35.17,317,0,317,0,8725,103,8872,0.011609558160505,2,27,27,"Artifact (5)"]
["many samples, low freq","UPN_Tr2_084",20,31022328,"T","A","ASXL1","ENST00000375687","missense_variant","Tgc/Agc|p.Cys605Ser/c.1813T>A",9798,103,9949,0.0103527992763092,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",1.424,"Tolerated",35.52,34.89,325,3,332,0.00903614457831325,9473,100,9617,0.0103982530934803,2,27,27,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_006",20,31022339,"G","T","ASXL1","ENST00000375687","missense_variant","tgG/tgT|p.Trp608Cys/c.1824G>T",3760,39,3804,0.0102523659305994,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.366,"Tolerated",32.08,31.54,204,0,204,0,3556,39,3600,0.0108333333333333,2,1,1,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_029",20,31022341,"C","A","ASXL1","ENST00000375687","missense_variant","aCt/aAt|p.Thr609Asn/c.1826C>A",15448,164,15727,0.0104279264958352,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.614,"Deleterious",32.01,31.12,2774,2,2783,0.000718648939992814,12674,162,12944,0.0125154511742892,2,48,49,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_007",20,31022341,"C","A","ASXL1","ENST00000375687","missense_variant","aCt/aAt|p.Thr609Asn/c.1826C>A",19597,225,19888,0.0113133547868061,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.614,"Deleterious",31.68,31.52,1253,0,1254,0,18344,225,18634,0.0120747021573468,2,48,49,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_086",20,31022341,"C","A","ASXL1","ENST00000375687","missense_variant","aCt/aAt|p.Thr609Asn/c.1826C>A",5452,102,5594,0.0182338219520915,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.614,"Deleterious",31.53,31.54,143,0,143,0,5309,102,5451,0.0187121629058888,2,48,49,"Artifact (4)"]
["inspected, many artifacts, many samples","UPN_Tr2_012",20,31022343,"G","A","ASXL1","ENST00000375687","missense_variant","Ggc/Agc|p.Gly610Ser/c.1828G>A",1470,30,1503,0.0199600798403194,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.547,"Deleterious",34.65,32.1,751,2,755,0.00264900662251656,719,28,748,0.0374331550802139,3.37329899640475E-007,5,5,"Artifact (5)"]
["many artifacts, strandbias, many samples","UPN_Tr2_001",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",4100,885,5010,0.1766467066,0,0,0,0,1,1,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",31.8,31.76,3691,884,4591,0.1925506426,409,1,419,0.0023866348,5.99394309603002E-035,111,111,"Artifact (8)"]
["many artifacts, strandbias, many samples","UPN_Tr2_023",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",9489,1103,10659,0.1034806267,0,1,0,0,1,1,0,0,3,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",32.11,31.69,6619,1096,7732,0.1417485773,2870,7,2927,0.0023915272,1.67384955151878E-147,111,111,"Artifact (8)"]
["many artifacts, strandbias, many samples","UPN_Tr2_034",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",2831,279,3129,0.0891658677,0,0,0,0,1,1,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",32.01,31.92,2022,272,2297,0.1184153243,809,7,832,0.0084134615,9.55842915481964E-029,111,111,"Artifact (13)"]
["many artifacts, strandbias, many samples","UPN_Tr2_054",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",8534,545,9133,0.0596737107,0,0,0,0,1,1,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",31.71,31.54,6974,539,7530,0.0715803453,1560,6,1603,0.0037429819,3.13474205216249E-037,111,111,"Artifact (13)"]
["many artifacts, strandbias, many samples","UPN_Tr2_093",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",4225,187,4421,0.0422981226,0,0,0,0,1,1,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",32.04,31.77,3581,186,3771,0.0493237868,644,1,650,0.0015384615,3.99492674012172E-012,111,111,"Artifact (13)"]
["many artifacts, strandbias, many samples","UPN_Tr2_075",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",4570,740,5333,0.1387586724,0,1,0,0,1,1,0,0,3,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",31.83,31.51,3851,737,4595,0.1603917301,719,3,738,0.0040650407,1.34883807645328E-045,111,111,"Artifact (8)"]
["many artifacts, strandbias, many samples","UPN_Tr2_097",20,31022413,"A","G","ASXL1","ENST00000375687","missense_variant","cAt/cGt|p.His633Arg/c.1898A>G",8329,446,8786,0.0507625768,0,0,0,0,1,1,0,0,2,0.0118,0,"NO","NA","NA","NO","rs201280462","NO","NO","NO","YES",-0.1,"Tolerated",32.13,31.69,6797,442,7244,0.0610160133,1532,4,1542,0.0025940337,2.77797255714368E-032,111,111,"Artifact (13)"]
["low freq, many artifacts, many samples","UPN_Tr2_001",20,31022414,"T","G","ASXL1","ENST00000375687","missense_variant","caT/caG|p.His633Gln/c.1899T>G",4947,61,5024,0.0121417197452229,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",1.019,"Tolerated",31.89,32,4530,61,4605,0.0132464712269273,417,0,419,0,2,19,20,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_083",20,31022414,"T","G","ASXL1","ENST00000375687","missense_variant","caT/caG|p.His633Gln/c.1899T>G",2917,45,2982,0.0150905432595573,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",1.019,"Tolerated",31.93,32,2606,45,2671,0.0168476226132535,311,0,311,0,2,19,20,"Artifact (6)"]
["Hotspot, homopolymer 8G","UPN_Tr2_024",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",5399,234,5478,0.0427163198247536,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.34,"NA",4145,193,4158,0.0464165464165464,1254,41,1320,0.0310606060606061,0.0469143305624281,110,229,"Artifact (5)"]
["Hotspot, homopolymer 8G","UPN_Tr2_034",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",3101,105,3161,0.0332173362859855,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.21,"NA",2320,81,2329,0.0347788750536711,781,24,832,0.0288461538461538,0.648156938623459,110,229,"Artifact (6)"]
["Hotspot, homopolymer 8G","UPN_Tr2_056",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",3569,120,3623,0.0331217223295611,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.75,"NA",3120,111,3147,0.0352716873212583,449,9,476,0.0189075630252101,0.11993637190555,110,229,"Artifact (6)"]
["Hotspot, homopolymer 8G","UPN_Tr2_064",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",2301,106,2311,0.0458675897879706,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.81,"NA",1889,91,1892,0.0480972515856237,412,15,419,0.035799522673031,0.364479473069868,110,229,"Artifact (5)"]
["Hotspot, homopolymer 8G","UPN_Tr2_068",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",1442,58,1449,0.0400276052449966,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.19,"NA",1309,53,1312,0.0403963414634146,133,5,137,0.0364963503649635,1,110,229,"Artifact (6)"]
["Hotspot, homopolymer 8G","UPN_Tr2_103",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",5955,272,5985,0.0454469507101086,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.95,"NA",4757,222,4768,0.0465604026845638,1198,50,1217,0.0410846343467543,0.535624622769583,110,229,"Artifact (5)"]
["Hotspot, homopolymer 8G","UPN_Tr2_108",20,31022441,"A","AG","ASXL1","ENST00000375687","frameshift_variant","ggt/ggGt|p.Gly646fs/c.1934dupG",9770,405,9879,0.0409960522320073,0,0,0,1,1,1,0,1,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.89,"NA",7794,328,7813,0.0419813131959555,1976,77,2066,0.037270087124879,0.613167529093487,110,229,"Artifact (5)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_025",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",12575,357,12981,0.0275017333025191,0,0,0,1,0,0,0,1,2,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.33,"NA",9779,286,10104,0.0283056215360253,2796,71,2877,0.0246784845324991,0.332311786090222,111,229,"Artifact (6)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_028",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",7403,310,7745,0.040025823111685,0,0,0,1,1,0,0,1,3,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.4,"NA",5441,237,5701,0.0415716540957727,1962,73,2044,0.0357142857142857,0.263795502046706,111,229,"Artifact (4)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_054",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",8730,379,9181,0.0412809062193661,0,0,0,1,1,1,0,1,4,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.05,"NA",7188,313,7555,0.0414295168762409,1542,66,1626,0.040590405904059,0.945203286194381,111,229,"Artifact (3)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_090",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",5966,252,6252,0.0403071017274472,0,0,0,1,1,0,0,1,3,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.28,"NA",5151,228,5407,0.042167560569632,815,24,845,0.0284023668639053,0.0598702705437375,111,229,"Artifact (4)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_074",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",997,60,1065,0.0563380281690141,0,0,0,1,1,1,0,1,4,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.1,"NA",894,52,954,0.0545073375262055,103,8,111,0.0720720720720721,0.512444107968963,111,229,"Artifact (2)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_083",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",2904,90,3011,0.0298904018598472,0,0,0,1,0,0,0,1,2,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.13,"NA",2599,78,2693,0.0289639806906795,305,12,318,0.0377358490566038,0.383392483381316,111,229,"Artifact (6)"]
["Homopolymer 8G, ins and del, many samples","UPN_Tr2_096",20,31022441,"AG","A","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly645fs/c.1934delG",8054,341,8426,0.0404699738903394,0,0,0,1,1,0,0,1,3,4.4879,"NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.27,"NA",6672,271,6972,0.0388697647733792,1382,70,1454,0.0481430536451169,0.108091127028497,111,229,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_044",20,31022510,"T","A","ASXL1","ENST00000375687","missense_variant","agT/agA|p.Ser665Arg/c.1995T>A",4967,56,5061,0.0110650069156293,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.025,"Tolerated",30.76,28.68,2445,36,2501,0.0143942423030788,2522,20,2560,0.0078125,0.0307911268702215,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_056",20,31022574,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys687Arg/c.2059T>C",3165,41,3216,0.0127487562189055,0,0,0,0,1,0,0,1,2,0.0116,"NO","NO","NA","NA","NO","rs140197482","NO","NO","NO","NO",0.027,"Tolerated",34.33,34.41,0,0,0,"NA",3165,41,3216,0.0127487562189055,1,1,1,"Artifact (3)"]
["low freq, many artifacts, many samples","UPN_Tr2_018",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",11890,240,12178,0.0197076695680736,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.11,"NA",7968,0,7999,0,3922,240,4179,0.0574300071787509,2,105,105,"Artifact (8)"]
["many samples","UPN_Tr2_003",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",1793,51,1851,0.0275526742301459,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.95,"NA",1147,0,1152,0,646,51,699,0.0729613733905579,2,105,105,"Artifact (6)"]
["many samples","UPN_Tr2_005",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",2987,72,3068,0.0234680573663625,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.87,"NA",1991,0,2000,0,996,72,1068,0.0674157303370786,2,105,105,"Artifact (6)"]
["many samples","UPN_Tr2_090",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",10295,247,10577,0.0233525574359459,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.98,"NA",6458,0,6483,0,3837,247,4094,0.0603321934538349,2,105,105,"Artifact (6)"]
["many samples","UPN_Tr2_012",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",10436,260,10748,0.0241905470785262,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.77,"NA",7315,0,7351,0,3121,260,3397,0.0765381218722402,2,105,105,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_069",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",24881,299,25314,0.0118116457296358,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.31,"NA",20551,0,20668,0,4330,299,4646,0.0643564356435644,2,105,105,"Artifact (8)"]
["many samples","UPN_Tr2_096",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",11438,307,11789,0.0260412248706421,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.11,"NA",6627,0,6658,0,4811,307,5131,0.059832391346716,2,105,105,"Artifact (6)"]
["inspected, strandbias","UPN_Tr2_111",20,31022790,"TG","T","ASXL1","ENST00000375687","frameshift_variant","tgc/|p.Cys759fs/c.2276delG",14221,435,14716,0.0295596629518891,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.07,"NA",8995,0,9033,0,5226,435,5683,0.076544078831603,2,105,105,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_006",20,31023002,"A","T","ASXL1","ENST00000375687","missense_variant","caA/caT|p.Gln829His/c.2487A>T",7289,102,7467,0.0136601044596223,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.739,"Tolerated",33.36,29.37,3681,45,3765,0.0119521912350598,3608,57,3702,0.0153970826580227,0.231399297078342,1,1,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_028",20,31023021,"A","ATTTTTTTTT","ASXL1","ENST00000375687","disruptive_inframe_insertion","act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT",23740,331,23932,0.0138308540865786,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.334,"Deleterious",32.02,"NA",12100,0,12167,0,11640,331,11765,0.0281342966425839,3.7728606643757E-102,45,46,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_061",20,31023021,"A","ATTTTTTTTT","ASXL1","ENST00000375687","disruptive_inframe_insertion","act/aTTTTTTTTTct|p.Thr836delinsIlePhePheSer/c.2506_2507insTTTTTTTTT",21125,239,21386,0.0111755353969887,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.334,"Deleterious",31.67,"NA",10892,0,11012,0,10233,239,10374,0.0230383651436283,2.42497829115145E-075,45,46,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_016",20,31023025,"TGAAGGATCC","T","ASXL1","ENST00000375687","disruptive_inframe_deletion","atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC",17439,221,17926,0.0123284614526386,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.033,"Tolerated",33.44,"NA",9109,0,9129,0,8330,221,8797,0.0251222007502558,5.56802264160261E-071,56,58,"Artifact (12)"]
["low freq, many artifacts, many samples","UPN_Tr2_044",20,31023025,"TGAAGGATCC","T","ASXL1","ENST00000375687","disruptive_inframe_deletion","atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC",7125,75,7405,0.0101282916948008,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.033,"Tolerated",33.16,"NA",3794,0,3817,0,3331,75,3588,0.0209030100334448,2.69110564262604E-025,56,58,"Artifact (12)"]
["low freq, many artifacts, many samples","UPN_Tr2_053",20,31023025,"TGAAGGATCC","T","ASXL1","ENST00000375687","disruptive_inframe_deletion","atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC",41865,516,43381,0.0118946082386298,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.033,"Tolerated",33.03,"NA",22348,0,22405,0,19517,516,20976,0.0245995423340961,3.48500890615865E-170,56,58,"Artifact (12)"]
["low freq, many artifacts, many samples","UPN_Tr2_096",20,31023025,"TGAAGGATCC","T","ASXL1","ENST00000375687","disruptive_inframe_deletion","atgaaggatcct/att|p.Met837_Pro840delinsIle/c.2511_2519delGAAGGATCC",21155,385,22239,0.0173119294932326,0,1,0,0,0,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.033,"Tolerated",33.53,"NA",11376,0,11411,0,9779,385,10828,0.0355559660140377,5.25453599681332E-128,56,58,"Artifact (12)"]
["low freq, many artifacts, many samples","UPN_Tr2_064",20,31023069,"T","G","ASXL1","ENST00000375687","missense_variant","Tca/Gca|p.Ser852Ala/c.2554T>G",17260,279,17654,0.015803783845021,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.907,"Tolerated",31.74,31.34,11788,274,12147,0.0225570099613073,5472,5,5507,0.000907935355002724,6.27373478214168E-038,29,29,"Artifact (8)"]
["many samples, low freq, neutral effect","UPN_Tr2_076",20,31023069,"T","G","ASXL1","ENST00000375687","missense_variant","Tca/Gca|p.Ser852Ala/c.2554T>G",22351,248,22740,0.010905892700088,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.907,"Tolerated",31.9,30.42,12438,233,12776,0.018237319974953,9913,15,9964,0.00150541951023685,4.11327456023675E-041,29,29,"Artifact (6)"]
["many samples, strandbias","UPN_Tr2_002",20,31023123,"G","C","ASXL1","ENST00000375687","missense_variant","Ggc/Cgc|p.Gly870Arg/c.2608G>C",18492,846,19390,0.0436307374935534,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.938,"Tolerated",32.57,31.36,8612,6,8651,0.000693561437984048,9880,840,10739,0.0782195735170872,2,79,79,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_044",20,31023123,"G","C","ASXL1","ENST00000375687","missense_variant","Ggc/Cgc|p.Gly870Arg/c.2608G>C",6391,95,6530,0.0145482388973966,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.938,"Tolerated",31.99,31.01,2807,4,2823,0.00141693234148069,3584,91,3707,0.0245481521445913,2,79,79,"Artifact (9)"]
["many samples","UPN_Tr2_011",20,31023123,"G","C","ASXL1","ENST00000375687","missense_variant","Ggc/Cgc|p.Gly870Arg/c.2608G>C",38683,1314,40160,0.0327191235059761,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.938,"Tolerated",32.63,31.44,18810,10,18890,0.000529380624669137,19873,1304,21270,0.0613070051716032,2,79,79,"Artifact (7)"]
["many samples, strandbias","UPN_Tr2_062",20,31023123,"G","C","ASXL1","ENST00000375687","missense_variant","Ggc/Cgc|p.Gly870Arg/c.2608G>C",20631,747,21445,0.0348332944742364,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.938,"Tolerated",32.48,30.95,11192,24,11256,0.00213219616204691,9439,723,10189,0.0709588772205319,2,79,79,"Artifact (6)"]
["many samples","UPN_Tr2_069",20,31023123,"G","C","ASXL1","ENST00000375687","missense_variant","Ggc/Cgc|p.Gly870Arg/c.2608G>C",25798,692,26566,0.0260483324550177,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.938,"Tolerated",32.8,31.08,15898,21,15974,0.00131463628396144,9900,671,10592,0.0633496978851964,2,79,79,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_017",20,31023234,"G","A","ASXL1","ENST00000375687","missense_variant","Gta/Ata|p.Val907Ile/c.2719G>A",7661,79,7743,0.010202763786646,0,0,0,0,1,0,0,0,1,"NO",0,"NO","NO","O","NO","rs201990697","NO",8.236E-006,"NO","NO",-0.304,"Tolerated",35.53,35.9,2084,72,2156,0.0333951762523191,5577,7,5587,0.00125290853767675,2,61,61,"Artifact (7)"]
["inspected, strandbias, many samples","UPN_Tr2_044",20,31023234,"G","A","ASXL1","ENST00000375687","missense_variant","Gta/Ata|p.Val907Ile/c.2719G>A",3772,97,3882,0.0249871200412159,0,0,0,0,1,1,0,1,3,"NO",0,"NO","NO","O","NO","rs201990697","NO",8.236E-006,"NO","NO",-0.304,"Tolerated",35.12,35.63,950,55,1014,0.0542406311637081,2822,42,2868,0.0146443514644351,2,61,61,"Artifact (4)"]
["strandbias, many samples","UPN_Tr2_076",20,31023234,"G","A","ASXL1","ENST00000375687","missense_variant","Gta/Ata|p.Val907Ile/c.2719G>A",21323,494,21839,0.0226200833371491,0,0,0,0,1,1,0,0,2,"NO",0,"NO","NO","O","NO","rs201990697","NO",8.236E-006,"NO","NO",-0.304,"Tolerated",35.16,35.67,8362,488,8861,0.0550727908813904,12961,6,12978,0.000462320850670365,2,61,61,"Artifact (4)"]
["strandbias, many samples","UPN_Tr2_087",20,31023234,"G","A","ASXL1","ENST00000375687","missense_variant","Gta/Ata|p.Val907Ile/c.2719G>A",24742,498,25267,0.0197095025131595,0,0,0,0,1,1,0,0,2,"NO",0,"NO","NO","O","NO","rs201990697","NO",8.236E-006,"NO","NO",-0.304,"Tolerated",35.04,35.64,8081,484,8571,0.0564694901411737,16661,14,16696,0.000838524197412554,2,61,61,"Artifact (6)"]
["inspected, many artifacts","UPN_Tr2_041",20,31023303,"T","C","ASXL1","ENST00000375687","missense_variant","Tgg/Cgg|p.Trp930Arg/c.2788T>C",2128,42,2183,0.0192395785616125,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.899,"Tolerated",31.08,30.83,1070,21,1098,0.0191256830601093,1058,21,1085,0.0193548387096774,1,1,1,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_004",20,31023411,"G","A","ASXL1","ENST00000375687","missense_variant","Gga/Aga|p.Gly966Arg/c.2896G>A",1171,21,1193,0.0176026823134954,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-0.82,"Tolerated",35.47,34.95,784,15,799,0.0187734668335419,387,6,394,0.0152284263959391,2,1,1,"Artifact (3)"]
["many artifacts, many samples","UPN_Tr2_089",20,31023460,"A","G","ASXL1","ENST00000375687","missense_variant","aAg/aGg|p.Lys982Arg/c.2945A>G",20293,212,20528,0.0103273577552611,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.116,"Tolerated",34.36,34.11,10101,107,10212,0.0104778691735213,10192,105,10316,0.0101783637068631,0.890222144313845,42,42,"Artifact (6)"]
["many artifacts, many samples","UPN_Tr2_049",20,31023460,"A","G","ASXL1","ENST00000375687","missense_variant","aAg/aGg|p.Lys982Arg/c.2945A>G",19921,227,20179,0.011249318598543,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.116,"Tolerated",33.42,33.44,9886,114,10011,0.0113874737788433,10035,113,10168,0.0111132966168371,0.893858305796095,42,42,"Artifact (6)"]
["many artifacts, many samples","UPN_Tr2_105",20,31023460,"A","G","ASXL1","ENST00000375687","missense_variant","aAg/aGg|p.Lys982Arg/c.2945A>G",20684,226,20940,0.010792741165234,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.116,"Tolerated",34.45,33.54,10302,118,10432,0.0113113496932515,10382,108,10508,0.0102778835173201,0.503752803264792,42,42,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_016",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",20135,499,20748,0.0240505108926162,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",32.05,31.13,13737,495,14295,0.0346274921301154,6398,4,6453,0.00061986672865334,4.07958983987243E-074,83,83,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_044",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",8700,174,8897,0.0195571540968866,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",32.05,31.27,6419,173,6605,0.0261922785768357,2281,1,2292,0.00043630017452007,2.17909186484669E-021,83,83,"Artifact (11)"]
["many samples, low freq, neutral effect","UPN_Tr2_037",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",52620,1461,54323,0.0268946854923329,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",32.17,31.56,36591,1454,38212,0.0380508740709725,16029,7,16111,0.000434485755074173,1.56382978465047E-211,83,83,"Artifact (8)"]
["many samples","UPN_Tr2_040",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",20855,653,21577,0.0302637067247532,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",32.16,31.49,14237,651,14930,0.0436034829202947,6618,2,6647,0.0003008876184745,3.99016588812614E-102,83,83,"Artifact (9)"]
["many samples, low freq, neutral effect","UPN_Tr2_075",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",40508,1219,41937,0.0290674106397692,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",31.63,31.27,26409,1199,27734,0.0432321338429365,14099,20,14203,0.00140815320706893,1.9264846921174E-185,83,83,"Artifact (7)"]
["many samples, low freq, neutral effect","UPN_Tr2_076",20,31023637,"C","G","ASXL1","ENST00000375687","missense_variant","gCc/gGc|p.Ala1041Gly/c.3122C>G",33540,1076,34747,0.0309667021613377,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.523,"Tolerated",31.81,31.1,22052,1058,23191,0.0456211461342762,11488,18,11556,0.00155763239875389,2.03429904751554E-159,83,83,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_044",20,31023710,"G","T","ASXL1","ENST00000375687","missense_variant","tgG/tgT|p.Trp1065Cys/c.3195G>T",6352,91,6460,0.0140866873065015,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.353,"Tolerated",34.44,33.23,4289,12,4312,0.00278293135435993,2063,79,2148,0.0367783985102421,2,1,1,"Artifact (2)"]
["many samples, low freq, no database","UPN_Tr2_003",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",4858,218,5089,0.0428374926311653,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",32.47,31.73,1974,4,1983,0.00201714573877963,2884,214,3106,0.0688989053444945,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_030",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",35410,1384,36929,0.0374773213463674,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",32.34,31.73,13622,22,13705,0.00160525355709595,21788,1362,23224,0.0586462280399587,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_038",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",62571,2638,65444,0.0403092720493857,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",32.27,31.67,23679,70,23848,0.00293525662529353,38892,2568,41596,0.0617367054524474,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_059",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",49488,1699,51728,0.0328448809155583,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",31.29,31.54,20028,41,20158,0.00203393193769223,29460,1658,31570,0.0525182134938232,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_072",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",25526,1485,27242,0.0545114161955804,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",31.2,31.45,8961,22,9016,0.00244010647737356,16565,1463,18226,0.0802699440359925,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_085",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",34682,1305,36378,0.0358733300346363,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",31.24,31.57,13787,26,13866,0.00187509014856483,20895,1279,22512,0.0568141435678749,2,111,111,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_110",20,31023723,"T","C","ASXL1","ENST00000375687","missense_variant","Tgt/Cgt|p.Cys1070Arg/c.3208T>C",38393,406,38912,0.0104337993421053,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.895,"Tolerated",32.93,32.16,14272,43,14345,0.00299756012547926,24121,363,24567,0.0147759189156185,2,111,111,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_004",20,31023955,"T","G","ASXL1","ENST00000375687","missense_variant","cTa/cGa|p.Leu1147Arg/c.3440T>G",5121,60,5208,0.0115207373271889,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.692,"Tolerated",32.48,31.33,3312,60,3392,0.017688679245283,1809,0,1816,0,1.10100354570315E-011,11,11,"Artifact (8)"]
["strandbias, many samples","UPN_Tr2_002",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",21027,1760,22839,0.0770611673,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",33.52,31.62,7617,23,7667,0.0029998696,13410,1737,15172,0.1144872133,2,111,111,"Artifact (11)"]
["strandbias, many samples","UPN_Tr2_089",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",24485,586,25101,0.0233456834,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",33.28,31.5,7994,28,8030,0.003486924,16491,558,17071,0.0326870131,2,111,111,"Artifact (11)"]
["strandbias, many samples","UPN_Tr2_052",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",35848,796,36763,0.0216522047,0,0,0,0,1,1,0,1,3,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",32.95,31.59,12047,55,12177,0.0045167118,23801,741,24586,0.0301391036,2,111,111,"Artifact (11)"]
["inspected, strandbias, many samples","UPN_Tr2_011",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",50183,3216,53561,0.0600436885,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",33.53,31.57,18723,65,18888,0.0034413384,31460,3151,34673,0.0908776281,2,111,111,"Artifact (11)"]
["strandbias, many samples","UPN_Tr2_071",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",28035,2124,30275,0.0701568951,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",32.79,31.55,9358,32,9435,0.0033916269,18677,2092,20840,0.1003838772,2,111,111,"Artifact (11)"]
["inspected, strandbias, many samples","UPN_Tr2_079",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",26175,1957,28225,0.0693356953,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",32.82,31.71,8292,37,8369,0.0044210778,17883,1920,19856,0.0966962127,2,111,111,"Artifact (11)"]
["strandbias, many samples","UPN_Tr2_088",20,31024033,"T","C","ASXL1","ENST00000375687","missense_variant","tTg/tCg|p.Leu1173Ser/c.3518T>C",45918,4278,50323,0.08501083,0,0,0,0,1,1,0,0,2,"NO","NO","COSM4385129","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO",8.236E-006,"NO","NO",-0.013,"Tolerated",32.76,31.61,13896,41,13997,0.0029291991,32022,4237,36326,0.1166382206,2,111,111,"Artifact (11)"]
["low freq, many artifacts, many samples","UPN_Tr2_056",20,31024065,"A","G","ASXL1","ENST00000375687","missense_variant","Aca/Gca|p.Thr1184Ala/c.3550A>G",5521,60,5613,0.0106894708711919,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.272,"Tolerated",32.23,31.55,2782,31,2831,0.0109501942776404,2739,29,2782,0.0104241552839684,0.897069065470804,1,1,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_044",20,31024488,"C","T","ASXL1","ENST00000375687","missense_variant","Ctt/Ttt|p.Leu1325Phe/c.3973C>T",5697,81,5781,0.0140114167,0,0,0,0,1,1,0,0,2,0.0465,0.003,"NO","NO","O","rs6057581","rs6057581","NO",0.008937,"NO","YES",-1.036,"Tolerated",32.78,32.2,1679,4,1685,0.0023738872,4018,77,4096,0.0187988281,2,1,1,"Artifact (9)"]
["low freq, many artifacts, many samples","UPN_Tr2_005",20,31024615,"T","G","ASXL1","ENST00000375687","missense_variant","gTc/gGc|p.Val1367Gly/c.4100T>G",3209,57,3286,0.0173463177115033,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.751,"Deleterious",31.93,30.26,1579,56,1647,0.0340012143290832,1630,1,1639,0.00061012812690665,5.07776882016029E-016,38,38,"Artifact (6)"]
["low bq, low freq, many samples","UPN_Tr2_068",20,31024615,"T","G","ASXL1","ENST00000375687","missense_variant","gTc/gGc|p.Val1367Gly/c.4100T>G",13562,157,13817,0.0113628139248752,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.751,"Deleterious",30.31,26.34,4660,107,4811,0.0222406983995011,8902,50,9006,0.00555185431934266,1.35582164189524E-017,38,38,"Artifact (4)"]
["many artifacts, ins and del, many samples","UPN_Tr2_017",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",7064,537,7093,0.0757084449457211,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.4,"NA",3569,537,3585,0.149790794979079,3495,0,3508,0,2,100,100,"Artifact (4)"]
["many artifacts, ins and del, many samples","UPN_Tr2_027",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",18221,1353,18282,0.0740072202166065,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.4,"NA",9958,1352,9989,0.135348883772149,8263,1,8293,0.00012058362474376,2,100,100,"Artifact (4)"]
["many artifacts, ins and del, many samples","UPN_Tr2_052",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",17868,1380,17957,0.0768502533830818,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.98,"NA",9888,1380,9928,0.139000805801773,7980,0,8029,0,2,100,100,"Artifact (4)"]
["many artifacts, ins and del, many samples","UPN_Tr2_012",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",10546,545,10581,0.0515074189585105,0,0,0,1,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.31,"NA",5072,545,5094,0.106988614055752,5474,0,5487,0,2,100,100,"Artifact (5)"]
["many artifacts, ins and del, many samples","UPN_Tr2_072",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",9903,242,9938,0.0243509760515194,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.12,"NA",3651,242,3667,0.065994000545405,6252,0,6271,0,2,100,100,"Artifact (7)"]
["many artifacts, ins and del, many samples","UPN_Tr2_095",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",11422,877,11449,0.0766005764695607,0,1,0,1,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.35,"NA",5503,877,5517,0.158963204640203,5919,0,5932,0,2,100,100,"Artifact (4)"]
["inspected, ins and del, many samples","UPN_Tr2_111",20,31024635,"G","GT","ASXL1","ENST00000375687","frameshift_variant","gtg/gtTg|p.Pro1377fs/c.4121dupT",14177,1056,14205,0.0743400211193242,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.39,"NA",6534,1056,6548,0.161270616982285,7643,0,7657,0,2,100,100,"Artifact (5)"]
["many artifacts, ins and del, many samples","UPN_Tr2_057",20,31024636,"TG","T","ASXL1","ENST00000375687","frameshift_variant","ggt/|p.Gly1376fs/c.4127delG",18453,217,19082,0.0113719735876742,0,0,0,1,0,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.95,"NA",10003,100,10493,0.00953016296578671,8450,117,8589,0.0136220747467691,2,24,27,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_048",20,31024717,"G","A","ASXL1","ENST00000375687","missense_variant","gGg/gAg|p.Gly1401Glu/c.4202G>A",3992,43,4059,0.0105937423010594,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.674,"Tolerated",33.25,33.4,3877,42,3943,0.0106517879786964,115,1,116,0.00862068965517241,1,1,1,"Artifact (4)"]
["strandbias, many samples","UPN_Tr2_015",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",18732,436,19258,0.0226399418423512,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",34.28,32.05,3267,386,3664,0.105349344978166,15465,50,15594,0.00320636142105938,5.24196153552365E-224,96,96,"Artifact (5)"]
["strandbias, many samples","UPN_Tr2_004",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",1572,71,1652,0.0429782082324455,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",34.26,31.54,307,69,376,0.183510638297872,1265,2,1276,0.00156739811912226,5.70917424926812E-044,96,96,"Artifact (6)"]
["strandbias, many samples","UPN_Tr2_042",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",24067,290,24557,0.0118092600887731,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",34.05,32.14,2820,209,3038,0.0687952600394997,21247,81,21519,0.00376411543287327,8.84726952119988E-124,96,96,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_010",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",19919,701,20728,0.0338189888074103,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",34.22,31.62,3068,660,3737,0.176612255820177,16851,41,16991,0.00241304219881114,0,96,96,"Artifact (5)"]
["strandbias, many samples","UPN_Tr2_057",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",21422,426,22046,0.0193232332395899,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",33.83,31.99,3909,370,4288,0.0862873134328358,17513,56,17758,0.00315350827795923,1.30669010733889E-202,96,96,"Artifact (7)"]
["strandbias, many samples","UPN_Tr2_078",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",19990,1135,21247,0.0534193062550007,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",33.45,31.6,5862,1081,6968,0.155137772675086,14128,54,14279,0.00378177743539464,0,96,96,"Artifact (5)"]
["strandbias, many samples","UPN_Tr2_084",20,31025007,"A","G","ASXL1","ENST00000375687","missense_variant","Acg/Gcg|p.Thr1498Ala/c.4492A>G",19777,702,20575,0.0341190765492102,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO",-0.22,"Tolerated",33.8,31.54,3991,663,4666,0.142091727389627,15786,39,15909,0.00245144257967188,0,96,96,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_024",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",6162,661,6842,0.0966091786027477,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.37,31.48,957,2,964,0.0020746887966805,5205,659,5878,0.112112963593059,2,111,112,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_032",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",5389,605,6012,0.100632069194943,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.6,31.69,1187,4,1195,0.00334728033472803,4202,601,4817,0.12476645214864,2,111,112,"Artifact (3)"]
["bad alignment, strandbias, many samples","UPN_Tr2_006",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",4868,996,5874,0.169560776302349,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.23,31.52,623,3,628,0.00477707006369427,4245,993,5246,0.189287075867327,2,111,112,"Artifact (3)"]
["bad alignment, strandbias, many samples","UPN_Tr2_054",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",14513,805,15358,0.0524156791248861,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.4,31.09,2977,5,2994,0.00167000668002672,11536,800,12364,0.0647039792947266,2,111,112,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_066",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",27892,2390,30349,0.078750535437741,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",33.46,31.41,14382,35,14456,0.00242114001106807,13510,2355,15893,0.148178443339835,2,111,112,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_074",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",12950,1696,14677,0.115554949921646,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.94,31.38,4840,14,4867,0.00287651530717074,8110,1682,9810,0.171457696228338,2,111,112,"Artifact (3)"]
["bad alignment, strandbias, many samples","UPN_Tr2_104",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",10751,567,11334,0.0500264690312335,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.36,31.51,1542,3,1545,0.00194174757281553,9209,564,9789,0.0576156910818265,2,111,112,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_111",20,31025059,"T","C","ASXL1","ENST00000375687","missense_variant","aTg/aCg|p.Met1515Thr/c.4544T>C",12717,570,13311,0.0428217263917061,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.593,"Deleterious",32.57,31.56,2563,8,2577,0.00310438494373302,10154,562,10734,0.0523569964598472,2,111,112,"Artifact (4)"]
["inspected, many artifacts","UPN_Tr2_006",21,36164521,"C","T","RUNX1","ENST00000437180","missense_variant","Gtg/Atg|p.Val452Met/c.1354G>A",2133,28,2163,0.0129449838187702,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.9,"Tolerated",35.36,36,0,0,0,"NA",2133,28,2163,0.0129449838187702,1,1,1,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_016",21,36164526,"C","G","RUNX1","ENST00000437180","missense_variant","aGc/aCc|p.Ser450Thr/c.1349G>C",3386,46,3438,0.0133798720186155,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.208,"Tolerated",33.66,32,1564,46,1615,0.0284829721362229,1822,0,1823,0,5.35195719207874E-016,36,36,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_011",21,36164526,"C","G","RUNX1","ENST00000437180","missense_variant","aGc/aCc|p.Ser450Thr/c.1349G>C",4472,67,4549,0.0147285117608266,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.208,"Tolerated",34.04,31.13,1610,66,1678,0.0393325387365912,2862,1,2871,0.000348310693138279,5.2681658716254E-028,36,36,"Artifact (8)"]
["low freq, many artifacts","UPN_Tr2_013",21,36164526,"C","G","RUNX1","ENST00000437180","missense_variant","aGc/aCc|p.Ser450Thr/c.1349G>C",1699,21,1725,0.0121739130434783,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.208,"Tolerated",34.19,30.29,504,19,524,0.0362595419847328,1195,2,1201,0.00166527893422148,1.29208693631803E-008,36,36,"Artifact (8)"]
["inspected, many artifacts, many samples","UPN_Tr2_094",21,36164542,"TG","T","RUNX1","ENST00000437180","frameshift_variant","ccc/|p.Ser445fs/c.1331delC",1819,22,1842,0.011943539630836,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",35.46,"NA",1322,22,1345,0.0163568773234201,497,0,497,0,2,12,12,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_055",21,36164557,"CG","C","RUNX1","ENST00000437180","frameshift_variant","tcc/|p.Ala440fs/c.1317delC",11284,128,11461,0.0111683099206003,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.12,"NA",4563,2,4590,0.000435729847494553,6721,126,6871,0.0183379420753893,2,18,18,"Artifact (5)"]
["bad alignment, strandbias, many samples","UPN_Tr2_002",21,36164578,"T","C","RUNX1","ENST00000437180","missense_variant","Acc/Gcc|p.Thr433Ala/c.1297A>G",2636,483,3128,0.154411764705882,1,1,0,0,1,1,0,0,4,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.338,"Deleterious",31.72,31.9,975,5,985,0.0050761421319797,1661,478,2143,0.223051796546897,2,81,81,"Artifact (2)"]
["bad alignment, strandbias, many samples","UPN_Tr2_005",21,36164578,"T","C","RUNX1","ENST00000437180","missense_variant","Acc/Gcc|p.Thr433Ala/c.1297A>G",633,106,742,0.142857142857143,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.338,"Deleterious",31.66,31.83,257,0,258,0,376,106,484,0.21900826446281,2,81,81,"Artifact (3)"]
["bad alignment, strandbias, many samples","UPN_Tr2_052",21,36164578,"T","C","RUNX1","ENST00000437180","missense_variant","Acc/Gcc|p.Thr433Ala/c.1297A>G",7714,296,8028,0.036870951669158,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.338,"Deleterious",32.13,31.78,2999,20,3028,0.00660501981505945,4715,276,5000,0.0552,2,81,81,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_040",21,36164578,"T","C","RUNX1","ENST00000437180","missense_variant","Acc/Gcc|p.Thr433Ala/c.1297A>G",5898,573,6488,0.0883168927250308,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.338,"Deleterious",32.6,31.69,2415,6,2427,0.00247218788627936,3483,567,4061,0.13962078305836,2,81,81,"Artifact (4)"]
["bad alignment, strandbias, many samples","UPN_Tr2_106",21,36164578,"T","C","RUNX1","ENST00000437180","missense_variant","Acc/Gcc|p.Thr433Ala/c.1297A>G",3783,55,3840,0.0143229166666667,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.338,"Deleterious",34.15,32.15,2696,6,2704,0.0022189349112426,1087,49,1136,0.0431338028169014,2,81,81,"Artifact (6)"]
["low bq, bad alignment, many samples","UPN_Tr2_105",21,36164605,"A","G","RUNX1","ENST00000437180","missense_variant","Tcg/Ccg|p.Ser424Pro/c.1270T>C",543,55,910,0.0604395604395604,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.784,"Deleterious",15.14,15.6,543,55,910,0.0604395604395604,0,0,0,"NA",1,8,8,"Artifact (3)"]
["low freq, many artifacts, many samples","UPN_Tr2_055",21,36164610,"T","C","RUNX1","ENST00000437180","missense_variant","gAg/gGg|p.Glu422Gly/c.1265A>G",730,30,2645,0.0113421550094518,0,0,0,0,0,0,0,1,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.524,"Deleterious",18.83,28.23,730,30,2645,0.0113421550094518,0,0,0,"NA",1,8,11,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_058",21,36164611,"C","A","RUNX1","ENST00000437180","stop_gained","Gag/Tag|p.Glu422*/c.1264G>T",1694,35,1744,0.0200688073394495,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",20.83,15.77,1694,35,1744,0.0200688073394495,0,0,0,"NA",1,15,15,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_025",21,36164619,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val419Gly/c.1256T>G",578,1443,2025,0.712592592592593,0,1,1,0,1,0,1,0,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.292,"Deleterious",17.28,15.8,574,1443,2021,0.714002968827313,4,0,4,0,0.00664077576425804,89,89,"Artifact (3)"]
["low bq, many samples, no database","UPN_Tr2_032",21,36164619,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val419Gly/c.1256T>G",152,397,552,0.719202898550725,0,0,1,0,1,0,1,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.292,"Deleterious",17.43,15.33,152,397,552,0.719202898550725,0,0,0,"NA",1,89,89,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_009",21,36164619,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val419Gly/c.1256T>G",565,942,1519,0.620144832126399,0,0,1,0,1,0,1,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.292,"Deleterious",15.76,15.14,564,942,1518,0.620553359683794,1,0,1,0,0.37491705374917,89,89,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_091",21,36164619,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val419Gly/c.1256T>G",587,536,1129,0.474756421612046,0,1,0,0,1,0,1,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.292,"Deleterious",15.15,15.51,587,536,1129,0.474756421612046,0,0,0,"NA",1,89,89,"Artifact (4)"]
["low bq, many samples, no database","UPN_Tr2_104",21,36164619,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val419Gly/c.1256T>G",622,673,1298,0.518489984591679,1,0,0,0,1,0,1,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-3.292,"Deleterious",15.11,15.32,616,673,1292,0.520897832817337,6,0,6,0,0.0121243070567342,89,89,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_063",21,36164623,"T","A","RUNX1","ENST00000437180","missense_variant","Atg/Ttg|p.Met418Leu/c.1252A>T",197,32,254,0.125984251968504,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.139,"Tolerated",19.95,15.19,79,30,118,0.254237288135593,118,2,136,0.0147058823529412,3.6466321518324E-009,1,5,"Artifact (2)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_030",21,36164626,"A","G","RUNX1","ENST00000437180","missense_variant","Tcc/Ccc|p.Ser417Pro/c.1249T>C",4765,100,4898,0.0204164965291956,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.167,"Tolerated",24.64,18,1650,84,1753,0.0479178551055334,3115,16,3145,0.00508744038155803,1.04178116204915E-023,11,11,"Artifact (5)"]
["inspected, many artifacts","UPN_Tr2_056",21,36164700,"T","A","RUNX1","ENST00000437180","missense_variant","cAg/cTg|p.Gln392Leu/c.1175A>T",1889,27,1923,0.0140405616224649,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.888,"Deleterious",33.35,34.74,0,0,0,"NA",1889,27,1923,0.0140405616224649,1,1,1,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_075",21,36164733,"A","T","RUNX1","ENST00000437180","missense_variant","cTg/cAg|p.Leu381Gln/c.1142T>A",1906,22,1950,0.0112820512820513,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-4.147,"Deleterious",35.23,34.82,1779,22,1823,0.0120680197476687,127,0,127,0,2,1,1,"Artifact (2)"]
["inspected, many artifacts","UPN_Tr2_028",21,36206715,"T","C","RUNX1","ENST00000437180","missense_variant","cAg/cGg|p.Gln266Arg/c.797A>G",1756,21,1783,0.0117779024116657,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.376,"Tolerated",35.11,34.76,1756,21,1783,0.0117779024116657,0,0,0,"NA",1,1,1,"Artifact (3)"]
["low bq, low freq, many artifacts","UPN_Tr2_012",21,36206768,"G","T","RUNX1","ENST00000437180","missense_variant","aaC/aaA|p.Asn248Lys/c.744C>A",2263,28,2294,0.012205754141238,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.957,"Deleterious",31.62,26,1340,11,1353,0.00813008130081301,923,17,941,0.0180658873538789,0.0511649391047622,1,1,"Artifact (4)"]
["many artifacts, strandbias, many samples","UPN_Tr2_016",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",6119,686,6824,0.10052754982415,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.38,31.75,4629,663,5302,0.125047152018106,1490,23,1522,0.0151116951379763,1.55326249255431E-048,111,111,"Artifact (4)"]
["many artifacts, strandbias, many samples","UPN_Tr2_041",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",18282,994,19340,0.0513960703205791,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.19,31.21,14594,951,15575,0.0610593900481541,3688,43,3765,0.0114209827357238,8.85018106296433E-046,111,111,"Artifact (5)"]
["many artifacts, strandbias, many samples","UPN_Tr2_048",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",19315,1531,20897,0.0732641048954395,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.2,30.97,15296,1496,16822,0.0889311615741291,4019,35,4075,0.00858895705521472,1.91839652324154E-099,111,111,"Artifact (5)"]
["many artifacts, strandbias, many samples","UPN_Tr2_010",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",10836,2014,12890,0.156245151280062,1,1,0,0,1,1,0,0,4,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.23,31.39,8816,1988,10831,0.183547225556274,2020,26,2059,0.0126274890723652,2.9802490882888E-124,111,111,"Artifact (3)"]
["many artifacts, strandbias, many samples","UPN_Tr2_091",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",6392,356,6761,0.052654932702263,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.54,31.54,4903,343,5252,0.0653084539223153,1489,13,1509,0.00861497680583168,6.85213917850647E-024,111,111,"Artifact (5)"]
["many artifacts, strandbias, many samples","UPN_Tr2_077",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",7064,1122,8206,0.136729222520107,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.16,31.15,5858,1115,6991,0.159490773852096,1206,7,1215,0.00576131687242798,2.414394885856E-072,111,111,"Artifact (5)"]
["many artifacts, strandbias, many samples","UPN_Tr2_096",21,36206851,"A","G","RUNX1","ENST00000437180","missense_variant","Ttt/Ctt|p.Phe221Leu/c.661T>C",8345,356,8724,0.0408069692801467,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-4.334,"Deleterious",32.48,31.92,6145,331,6492,0.0509858287122612,2200,25,2232,0.0112007168458781,5.75397824259849E-020,111,111,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_083",21,36231774,"G","A","RUNX1","ENST00000437180","stop_gained","Cga/Tga|p.Arg204*/c.610C>T",12310,177,12495,0.0141656662665066,0,0,0,0,1,0,0,1,2,"NO","NO","COSM25124","haematopoietic_and_lymphoid_tissue",6,"NO","NO","NO","NO","NO","NO","NA","NA",35.22,35.02,12310,177,12495,0.0141656662665066,0,0,0,"NA",1,1,1,"Artifact (2)"]
["many samples, low freq, many artifacts","UPN_Tr2_051",21,36231870,"T","C","RUNX1","ENST00000437180","missense_variant","Agc/Ggc|p.Ser172Gly/c.514A>G",22917,259,23294,0.0111187430239547,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.71,"Deleterious",30.87,31.62,11593,126,11768,0.010707002039429,11324,133,11526,0.0115391289259066,0.573915823413499,20,20,"Artifact (4)"]
["many samples, low freq, many artifacts","UPN_Tr2_054",21,36231870,"T","C","RUNX1","ENST00000437180","missense_variant","Agc/Ggc|p.Ser172Gly/c.514A>G",19580,254,19958,0.0127267261248622,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.71,"Deleterious",30.24,31.93,9911,119,10079,0.0118067268578232,9669,135,9879,0.0136653507440024,0.255588997918927,20,20,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_056",21,36259175,"A","T","RUNX1","ENST00000437180","missense_variant","Tgg/Agg|p.Trp106Arg/c.316T>A",4846,70,4939,0.0141729094958494,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-11.81,"Deleterious",34.74,35.47,4846,70,4939,0.0141729094958494,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low bq, many samples","UPN_Tr2_069",21,36259213,"T","G","RUNX1","ENST00000437180","missense_variant","gAc/gCc|p.Asp93Ala/c.278A>C",355,227,584,0.388698630136986,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.24,"Deleterious",31.95,26.2,296,0,297,0,59,227,287,0.790940766550523,2.63795663731237E-106,30,30,"Artifact (2)"]
["low bq, many samples","UPN_Tr2_085",21,36259213,"T","G","RUNX1","ENST00000437180","missense_variant","gAc/gCc|p.Asp93Ala/c.278A>C",466,251,723,0.34716459197787,0,1,0,0,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.24,"Deleterious",30.56,25.45,364,0,367,0,102,251,356,0.705056179775281,5.29238696244195E-110,30,30,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_035",21,36259316,"C","G","RUNX1","ENST00000437180","missense_variant","Ggc/Cgc|p.Gly59Arg/c.175G>C",4209,56,4269,0.013117826188803,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.262,"Deleterious",34.77,30.32,394,54,449,0.120267260579065,3815,2,3820,0.000523560209424084,9.0684177634937E-052,14,14,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_035",21,36259344,"TG","T","RUNX1","ENST00000437180","frameshift_variant","cca/|p.Pro49fs/c.146delC",4222,51,4281,0.0119131044148563,0,0,0,1,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",35.4,"NA",460,1,462,0.00216450216450216,3762,50,3819,0.0130924325739722,2,15,16,"Artifact (6)"]
["many samples","UPN_Tr2_016",21,36259363,"G","C","RUNX1","ENST00000437180","missense_variant","cCt/cGt|p.Pro43Arg/c.128C>G",4254,97,4359,0.0222528102775866,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.741,"Deleterious",32.17,31.29,458,0,459,0,3796,97,3900,0.0248717948717949,2,58,58,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_031",21,36259363,"G","C","RUNX1","ENST00000437180","missense_variant","cCt/cGt|p.Pro43Arg/c.128C>G",5143,93,5242,0.0177413201068295,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.741,"Deleterious",32.16,31.81,530,1,531,0.00188323917137476,4613,92,4711,0.019528762470813,2,58,58,"Artifact (7)"]
["inspected, strandbias","UPN_Tr2_038",21,36259363,"G","C","RUNX1","ENST00000437180","missense_variant","cCt/cGt|p.Pro43Arg/c.128C>G",11907,317,12250,0.0258775510204082,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.741,"Deleterious",32.12,31.6,1029,1,1033,0.000968054211035818,10878,316,11217,0.0281715253632879,2,58,58,"Artifact (4)"]
["many samples","UPN_Tr2_081",21,36259363,"G","C","RUNX1","ENST00000437180","missense_variant","cCt/cGt|p.Pro43Arg/c.128C>G",1421,49,1473,0.03326544467074,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-6.741,"Deleterious",32.15,31.31,180,0,180,0,1241,49,1293,0.0378963650425367,2,58,58,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_005",21,44514873,"T","C","U2AF1","ENST00000291552","missense_variant","aAg/aGg|p.Lys125Arg/c.374A>G",2157,22,2188,0.010054844606947,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.169,"Tolerated",31.97,33.18,1082,11,1100,0.01,1075,11,1088,0.0101102941176471,1,3,4,"Artifact (4)"]
["many samples, low freq, neutral effect","UPN_Tr2_021","X",15818069,"A","G","ZRSR2","ENST00000307771","missense_variant","Aga/Gga|p.Arg66Gly/c.196A>G",6296,70,6402,0.0109340830990316,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.07,"Tolerated",34.7,34.34,3168,35,3217,0.0108797015853279,3128,35,3185,0.010989010989011,1,10,10,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_060","X",15821821,"C","T","ZRSR2","ENST00000307771","missense_variant","Cat/Tat|p.His72Tyr/c.214C>T",1165,20,1188,0.0168350168350168,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.427,"Deleterious",35.11,33.8,1165,20,1188,0.0168350168350168,0,0,0,"NA",1,2,2,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_035","X",15821881,"A","G","ZRSR2","ENST00000307771","missense_variant","Aag/Gag|p.Lys92Glu/c.274A>G",3968,60,4040,0.0148514851485149,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.372,"Tolerated",34.19,35.22,2000,30,2031,0.0147710487444609,1968,30,2009,0.0149328023892484,1,2,2,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_039","X",15821882,"A","G","ZRSR2","ENST00000307771","missense_variant","aAg/aGg|p.Lys92Arg/c.275A>G",1930,20,1952,0.0102459016393443,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.3,"Tolerated",34.17,34.5,972,10,982,0.010183299389002,958,10,970,0.0103092783505155,1,26,26,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_044","X",15821894,"C","A","ZRSR2","ENST00000307771","missense_variant","gCt/gAt|p.Ala96Asp/c.287C>A",788,37,826,0.0447941888619855,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.041,"Tolerated",31.79,32.35,395,19,415,0.0457831325301205,393,18,411,0.0437956204379562,1,1,1,"Artifact (1)"]
["low freq, many artifacts, many samples","UPN_Tr2_062","X",15821895,"TA","T","ZRSR2","ENST00000307771","frameshift_variant","aaa/|p.Lys98fs/c.294delA",2805,29,2846,0.0101897399859452,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.3,"NA",1416,14,1437,0.00974251913709116,1389,15,1409,0.0106458481192335,0.853645608435915,14,14,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_039","X",15821899,"A","G","ZRSR2","ENST00000307771","missense_variant","Aaa/Gaa|p.Lys98Glu/c.292A>G",1917,30,1951,0.0153767298821117,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.785,"Tolerated",34.64,33.9,963,15,980,0.0153061224489796,954,15,971,0.0154479917610711,1,3,3,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_006","X",15826377,"G","T","ZRSR2","ENST00000307771","missense_variant","Gat/Tat|p.Asp141Tyr/c.421G>T",3683,39,3723,0.0104754230459307,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-3.494,"Deleterious",35.3,34.87,3683,39,3723,0.0104754230459307,0,0,0,"NA",1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_006","X",15833807,"C","T","ZRSR2","ENST00000307771","missense_variant","Cgt/Tgt|p.Arg189Cys/c.565C>T",11623,127,11753,0.0108057517229643,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-7.059,"Deleterious",35.67,35.83,11623,127,11753,0.0108057517229643,0,0,0,"NA",1,2,2,"Artifact (2)"]
["low freq, many artifacts, many samples","UPN_Tr2_048","X",15833956,"C","G","ZRSR2","ENST00000307771","missense_variant","gaC/gaG|p.Asp238Glu/c.714C>G",9923,104,10045,0.0103534096565455,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.475,"Tolerated",32.26,30.22,7064,99,7178,0.013792142658122,2859,5,2867,0.00174398325776073,1.0251164511147E-009,53,53,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_012","X",15833956,"C","G","ZRSR2","ENST00000307771","missense_variant","gaC/gaG|p.Asp238Glu/c.714C>G",8612,120,8745,0.0137221269296741,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.475,"Tolerated",33.25,30.71,3879,117,4004,0.0292207792207792,4733,3,4741,0.000632777894958869,3.56438081942866E-036,53,53,"Artifact (8)"]
["low freq, many artifacts, many samples","UPN_Tr2_077","X",15833956,"C","G","ZRSR2","ENST00000307771","missense_variant","gaC/gaG|p.Asp238Glu/c.714C>G",14750,281,15054,0.0186661352464461,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.475,"Tolerated",32.81,30.74,8548,266,8834,0.0301109350237718,6202,15,6220,0.00241157556270096,3.5821591854351E-044,53,53,"Artifact (7)"]
["low freq, many artifacts","UPN_Tr2_056","X",15836719,"A","T","ZRSR2","ENST00000307771","missense_variant","Aat/Tat|p.Asn261Tyr/c.781A>T",9170,102,9351,0.0109079242861726,0,0,0,0,1,0,0,1,2,"NO","NO","COSM211060","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-7.556,"Deleterious",33.32,27.84,4654,34,4728,0.0071912013536379,4516,68,4623,0.0147090633787584,0.000459935700592078,1,1,"Artifact (1)"]
["low freq, many artifacts","UPN_Tr2_047","X",15838436,"T","C","ZRSR2","ENST00000307771","missense_variant","Tgt/Cgt|p.Cys312Arg/c.934T>C",2005,22,2034,0.0108161258603736,0,0,0,0,1,0,0,1,2,"NO","NO","COSM4385296","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO",-11.383,"Deleterious",33.73,32.36,1010,11,1025,0.0107317073170732,995,11,1009,0.0109018830525273,1,1,1,"Artifact (1)"]
["many samples, low freq, no database","UPN_Tr2_017","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",2662,142,2811,0.0505158306652437,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.51,31.52,655,2,661,0.00302571860816944,2007,140,2150,0.0651162790697674,2,82,82,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_029","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",6436,387,6850,0.0564963503649635,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.56,31.31,1377,3,1384,0.00216763005780347,5059,384,5466,0.0702524698133919,2,82,82,"Artifact (6)"]
["many samples","UPN_Tr2_037","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",16367,792,17200,0.046046511627907,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.59,31.45,4009,2,4015,0.00049813200498132,12358,790,13185,0.0599165718619644,2,82,82,"Artifact (7)"]
["many samples","UPN_Tr2_040","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",15049,848,15926,0.0532462639708653,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.55,31.53,3644,3,3650,0.000821917808219178,11405,845,12276,0.0688334962528511,2,82,82,"Artifact (7)"]
["many samples","UPN_Tr2_077","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",1985,65,2055,0.0316301703163017,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.34,30.38,1182,3,1188,0.00252525252525253,803,62,867,0.0715109573241061,2,82,82,"Artifact (7)"]
["many samples","UPN_Tr2_081","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",4954,211,5177,0.0407571952868457,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.96,30.99,2305,1,2309,0.00043308791684712,2649,210,2868,0.0732217573221757,2,82,82,"Artifact (7)"]
["many samples, low freq, no database","UPN_Tr2_082","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",4204,91,4311,0.0211087914636975,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.68,29.38,3091,10,3112,0.0032133676092545,1113,81,1199,0.0675562969140951,2,82,82,"Artifact (6)"]
["many samples","UPN_Tr2_083","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",2138,98,2241,0.0437304774654172,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.2,30.86,1197,2,1200,0.00166666666666667,941,96,1041,0.0922190201729107,2,82,82,"Artifact (7)"]
["many samples","UPN_Tr2_084","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",2888,94,2987,0.0314697020421828,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.15,30.85,1674,2,1679,0.00119118522930316,1214,92,1308,0.0703363914373089,2,82,82,"Artifact (7)"]
["low freq, many artifacts, many samples","UPN_Tr2_085","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",1950,38,1991,0.0190858864892014,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.72,31.05,1444,2,1448,0.00138121546961326,506,36,543,0.0662983425414365,2,82,82,"Artifact (9)"]
["many samples","UPN_Tr2_087","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",2219,66,2292,0.0287958115183246,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.42,31.45,1532,2,1536,0.00130208333333333,687,64,756,0.0846560846560847,2,82,82,"Artifact (7)"]
["many samples, low freq, no database","UPN_Tr2_088","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",3511,109,3630,0.0300275482093664,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",33.6,31.11,2523,4,2536,0.00157728706624606,988,105,1094,0.0959780621572212,2,82,82,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_098","X",15841096,"G","C","ZRSR2","ENST00000307771","missense_variant","Gaa/Caa|p.Glu394Gln/c.1180G>C",4940,50,4994,0.0100120144173008,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.197,"Tolerated",32.38,31.56,967,0,968,0,3973,50,4026,0.0124192747143567,2,82,82,"Artifact (9)"]
["many samples, low freq, no database","UPN_Tr2_002","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1473,31,1510,0.0205298013245033,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34,31.61,1472,7,1485,0.00471380471380471,1,24,25,0.96,2.72096384069275E-045,37,37,"Artifact (4)"]
["low freq, many artifacts, many samples","UPN_Tr2_022","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3550,40,3599,0.0111141983884412,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",35.06,30.08,3549,24,3582,0.0067001675041876,1,16,17,0.941176470588235,3.01759789214787E-032,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_026","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3530,44,3586,0.0122699386503067,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.88,31.2,3530,5,3546,0.00141003948110547,0,39,40,0.975,7.29051795446723E-087,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_089","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2124,28,2158,0.0129749768303985,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.73,31.29,2124,6,2136,0.00280898876404494,0,22,22,1,2.24415330888298E-047,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_042","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",4704,61,4783,0.0127535019862011,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.17,32.62,4704,26,4746,0.00547829751369574,0,35,37,0.945945945945946,2.6426836962759E-072,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_028","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1692,20,1716,0.0116550116550117,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.68,29.2,1692,8,1704,0.00469483568075117,0,12,12,1,9.89325595315526E-026,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_043","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2675,36,2721,0.0132304299889746,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.09,32.19,2675,11,2694,0.00408314773570898,0,25,27,0.925925925925926,1.54648627218172E-052,37,37,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_029","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1377,23,1405,0.0163701067615658,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.97,30.61,1377,3,1384,0.00216763005780347,0,20,21,0.952380952380952,5.9019836263334E-042,37,37,"Artifact (7)"]
["many samples, low freq, no database","UPN_Tr2_031","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2448,25,2484,0.0100644122383253,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.99,32.28,2447,12,2469,0.00486026731470231,1,13,15,0.866666666666667,3.5997525195525E-027,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_045","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1122,21,1148,0.0182926829268293,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.06,30.86,1122,5,1132,0.00441696113074205,0,16,16,1,5.57475403479341E-032,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_046","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2177,25,2212,0.0113019891500904,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",33.92,32.76,2177,14,2200,0.00636363636363636,0,11,12,0.916666666666667,3.09108999403429E-023,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_047","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2812,37,2860,0.0129370629370629,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.18,32.59,2811,10,2831,0.00353232073472271,1,27,29,0.931034482758621,6.33317431351812E-056,37,37,"Artifact (5)"]
["low freq, many artifacts, many samples","UPN_Tr2_035","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",4713,48,4774,0.0100544616673649,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.85,31.73,4712,17,4740,0.00358649789029536,1,31,34,0.911764705882353,1.2032050870777E-066,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_036","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2418,31,2455,0.0126272912423625,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.68,30.9,2382,8,2394,0.00334168755221387,36,23,61,0.377049180327869,3.28797673147641E-033,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_006","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2563,73,2664,0.0274024024024024,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.27,31.97,2563,17,2598,0.00654349499615089,0,56,66,0.848484848484849,6.05104015884556E-101,37,37,"Artifact (3)"]
["many samples, low freq, no database","UPN_Tr2_050","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1498,49,1552,0.0315721649484536,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",33.86,31.55,1498,5,1507,0.0033178500331785,0,44,45,0.977777777777778,4.31964814848508E-080,37,37,"Artifact (4)"]
["many samples, low freq, no database","UPN_Tr2_037","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3985,46,4052,0.0113524185587364,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.66,33.39,3985,16,4015,0.00398505603985056,0,30,37,0.810810810810811,2.01626314816843E-064,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_038","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2903,37,2947,0.0125551408211741,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.85,30.68,2901,8,2914,0.00274536719286205,2,29,33,0.878787878787879,4.74738575376381E-060,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_053","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",4148,58,4220,0.0137440758293839,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",33.73,32.17,4148,8,4170,0.00191846522781775,0,50,50,1,5.00236437902573E-108,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_007","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2149,26,2181,0.0119211370930766,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.75,30.54,2149,7,2162,0.0032377428307123,0,19,19,1,3.35509080898688E-041,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_008","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3022,35,3064,0.0114229765013055,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.44,31.54,3013,7,3024,0.00231481481481481,9,28,40,0.7,7.30269516860425E-054,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_009","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",4558,89,4661,0.0190946148895087,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.65,30.85,4553,14,4578,0.00305810397553517,5,75,83,0.903614457831325,7.48919005987561E-143,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_010","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3500,47,3554,0.0132245357343838,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.42,32.62,3482,15,3501,0.00428449014567267,18,32,53,0.60377358490566,9.67367357847352E-054,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_011","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",3197,43,3253,0.0132185674761758,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.68,31.47,3193,8,3208,0.00249376558603491,4,35,45,0.777777777777778,1.9838485402576E-070,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_055","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",4386,67,4467,0.0149988806805462,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.01,31.79,4386,13,4410,0.00294784580498866,0,54,57,0.947368421052632,7.59536674349233E-113,37,37,"Artifact (5)"]
["many samples, low freq, no database","UPN_Tr2_090","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",734,33,768,0.04296875,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.83,31.12,734,1,736,0.00135869565217391,0,32,32,1,8.1284404386217E-056,37,37,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_057","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1854,31,1892,0.016384778012685,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.08,30.39,1842,3,1851,0.00162074554294976,12,28,41,0.682926829268293,1.7975342203868E-049,37,37,"Artifact (7)"]
["many samples, low freq, no database","UPN_Tr2_058","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2303,27,2340,0.0115384615384615,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.03,30.85,2303,8,2321,0.003446790176648,0,19,19,1,3.04549278677771E-041,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_012","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",985,23,1011,0.0227497527200791,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.63,33.17,984,9,995,0.00904522613065327,1,14,16,0.875,1.0377025120799E-024,37,37,"Artifact (4)"]
["many samples, low freq, no database","UPN_Tr2_092","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1089,38,1131,0.0335985853227233,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.58,31.39,1089,8,1101,0.0072661217075386,0,30,30,1,5.30143819772271E-052,37,37,"Artifact (4)"]
["many samples, low freq, no database","UPN_Tr2_072","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1111,23,1142,0.0201401050788091,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",33.72,32.43,1111,8,1124,0.00711743772241993,0,15,18,0.833333333333333,1.06699659884669E-028,37,37,"Artifact (4)"]
["many samples, low freq, no database","UPN_Tr2_095","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2006,25,2036,0.012278978388998,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.7,31.2,2006,6,2016,0.00297619047619048,0,19,20,0.95,3.3381172156174E-041,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_096","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1547,22,1572,0.0139949109414758,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.75,31.09,1547,6,1556,0.0038560411311054,0,16,16,1,1.24966198508849E-033,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_097","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1761,23,1787,0.012870733072188,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.48,30.78,1761,4,1768,0.00226244343891403,0,19,19,1,1.98405488622163E-041,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_100","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1964,24,1995,0.0120300751879699,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.76,31.75,1962,4,1972,0.00202839756592292,2,20,23,0.869565217391304,7.04269393257028E-042,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_103","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",2344,33,2380,0.0138655462184874,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.37,29.76,2340,9,2352,0.0038265306122449,4,24,28,0.857142857142857,5.12443474318852E-046,37,37,"Artifact (6)"]
["many samples, low freq, no database","UPN_Tr2_110","X",15841097,"A","G","ZRSR2","ENST00000307771","missense_variant","gAa/gGa|p.Glu394Gly/c.1181A>G",1123,20,1144,0.0174825174825175,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.371,"Tolerated",34.64,30.75,1116,2,1119,0.00178731009830206,7,18,25,0.72,5.96255083215949E-032,37,37,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_015","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",2527,27,2556,0.0105633802816901,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",34.46,34.89,2527,27,2556,0.0105633802816901,0,0,0,"NA",1,7,7,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_027","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",2091,23,2123,0.0108337258596326,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",34.3,34.48,2091,23,2123,0.0108337258596326,0,0,0,"NA",1,7,7,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_046","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",2169,26,2199,0.0118235561618918,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",33.47,34,2169,26,2199,0.0118235561618918,0,0,0,"NA",1,7,7,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_048","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",3395,48,3452,0.0139049826187717,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",33.56,33.44,3395,48,3452,0.0139049826187717,0,0,0,"NA",1,7,7,"Artifact (6)"]
["low freq, many artifacts, many samples","UPN_Tr2_086","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",2454,25,2489,0.0100441944556047,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",33.1,31.88,2454,25,2489,0.0100441944556047,0,0,0,"NA",1,7,7,"Artifact (7)"]
["many samples, low freq, neutral effect","UPN_Tr2_095","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",1998,23,2023,0.0113692535837865,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",33.99,34.78,1992,22,2016,0.0109126984126984,6,1,7,0.142857142857143,0.0771053418608866,7,7,"Artifact (6)"]
["many samples, low freq, neutral effect","UPN_Tr2_107","X",15841111,"A","G","ZRSR2","ENST00000307771","missense_variant","Agt/Ggt|p.Ser399Gly/c.1195A>G",1525,21,1546,0.0135834411384217,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.894,"Tolerated",34.2,34.76,1525,21,1546,0.0135834411384217,0,0,0,"NA",1,7,7,"Artifact (6)"]
["low freq, many artifacts","UPN_Tr2_006","X",15841115,"G","A","ZRSR2","ENST00000307771","missense_variant","aGt/aAt|p.Ser400Asn/c.1199G>A",2568,26,2596,0.0100154083204931,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.781,"Tolerated",34.49,28.35,2568,26,2596,0.0100154083204931,0,0,0,"NA",1,1,1,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_041","X",15841122,"C","A","ZRSR2","ENST00000307771","missense_variant","caC/caA|p.His402Gln/c.1206C>A",3202,33,3245,0.0101694915254237,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-1.711,"Tolerated",32.93,30.42,3202,33,3245,0.0101694915254237,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_052","X",15841123,"A","G","ZRSR2","ENST00000307771","missense_variant","Agg/Ggg|p.Arg403Gly/c.1207A>G",2522,29,2559,0.0113325517780383,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.497,"Tolerated",33.95,30.86,2522,29,2559,0.0113325517780383,0,0,0,"NA",1,3,3,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_057","X",15841123,"A","G","ZRSR2","ENST00000307771","missense_variant","Agg/Ggg|p.Arg403Gly/c.1207A>G",1811,23,1839,0.0125067971723763,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.497,"Tolerated",34.07,33.57,1811,23,1839,0.0125067971723763,0,0,0,"NA",1,3,3,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_093","X",15841123,"A","G","ZRSR2","ENST00000307771","missense_variant","Agg/Ggg|p.Arg403Gly/c.1207A>G",1506,22,1531,0.0143696930111039,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO",-2.497,"Tolerated",34.36,35.64,1506,22,1531,0.0143696930111039,0,0,0,"NA",1,3,3,"Artifact (3)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_059","X",15841139,"A","C","ZRSR2","ENST00000307771","missense_variant","cAc/cCc|p.His408Pro/c.1223A>C",2578,48,2648,0.0181268882175227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.059,"Tolerated",22.11,15.25,2578,48,2648,0.0181268882175227,0,0,0,"NA",1,4,5,"Artifact (6)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_061","X",15841139,"A","C","ZRSR2","ENST00000307771","missense_variant","cAc/cCc|p.His408Pro/c.1223A>C",1794,35,1841,0.0190114068441065,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.059,"Tolerated",22.22,15.4,1794,35,1841,0.0190114068441065,0,0,0,"NA",1,4,5,"Artifact (6)"]
["low bq, bad alignment, many samples","UPN_Tr2_084","X",15841139,"A","C","ZRSR2","ENST00000307771","missense_variant","cAc/cCc|p.His408Pro/c.1223A>C",1610,42,1667,0.0251949610077984,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.059,"Tolerated",21.72,15.05,1610,42,1667,0.0251949610077984,0,0,0,"NA",1,4,5,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_087","X",15841139,"A","C","ZRSR2","ENST00000307771","missense_variant","cAc/cCc|p.His408Pro/c.1223A>C",1491,30,1531,0.0195950359242325,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.059,"Tolerated",22.45,16.17,1491,30,1531,0.0195950359242325,0,0,0,"NA",1,4,5,"Artifact (6)"]
["low bq, low freq, many artifacts","UPN_Tr2_036","X",15841139,"A","G","ZRSR2","ENST00000307771","missense_variant","cAc/cGc|p.His408Arg/c.1223A>G",2388,27,2430,0.0111111111111111,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.434,"Tolerated",26.8,29.96,2352,27,2394,0.0112781954887218,36,0,36,0,1,1,5,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_062","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",800,23,835,0.0275449101796407,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.845,"Tolerated",21.3,16.22,800,23,835,0.0275449101796407,0,0,0,"NA",1,5,5,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_063","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",912,33,955,0.0345549738219895,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.845,"Tolerated",21.09,15.15,912,33,955,0.0345549738219895,0,0,0,"NA",1,5,5,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_075","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",1124,32,1159,0.0276100086281277,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.845,"Tolerated",21.83,16.06,1124,32,1159,0.0276100086281277,0,0,0,"NA",1,5,5,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_077","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",1143,29,1187,0.0244313395113732,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.845,"Tolerated",21.07,15.1,1143,29,1187,0.0244313395113732,0,0,0,"NA",1,5,5,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_088","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",2414,93,2519,0.036919412465264,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.845,"Tolerated",21.52,15.1,2414,93,2519,0.036919412465264,0,0,0,"NA",1,5,5,"Artifact (4)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_006","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2548,33,2596,0.0127118644067797,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",22.26,15.73,2547,33,2595,0.0127167630057803,1,0,1,0,1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_050","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1463,20,1503,0.0133067198935462,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",21.34,15.1,1463,20,1503,0.0133067198935462,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_051","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2032,26,2083,0.0124819971195391,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",22.12,15.69,2032,26,2083,0.0124819971195391,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_010","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",3457,38,3525,0.0107801418439716,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",22.14,15.97,3429,37,3496,0.01058352402746,28,1,29,0.0344827586206897,0.27262867536008,23,23,"Artifact (8)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_055","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",4289,61,4403,0.0138541903247786,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",21.56,16.03,4289,61,4403,0.0138541903247786,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_056","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1397,27,1444,0.0186980609418283,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",21.35,17.26,1393,26,1439,0.0180681028492008,4,1,5,0.2,0.0913994107958892,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_058","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2262,36,2314,0.0155574762316335,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",22.21,15.83,2262,36,2314,0.0155574762316335,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_092","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1073,21,1098,0.0191256830601093,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",20.05,15.05,1073,21,1098,0.0191256830601093,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, many samples","UPN_Tr2_068","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2113,133,2275,0.0584615384615385,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.33,15.25,2113,133,2275,0.0584615384615385,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_069","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1241,55,1308,0.0420489296636086,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.52,15.02,1241,55,1308,0.0420489296636086,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_078","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",941,73,1027,0.071080817916261,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.48,15.03,941,73,1027,0.071080817916261,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_079","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1033,61,1110,0.054954954954955,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.65,15.21,1033,61,1110,0.054954954954955,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_080","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",746,41,796,0.0515075376884422,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.05,15.12,746,41,796,0.0515075376884422,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_082","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2877,161,3075,0.0523577235772358,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.68,15.01,2877,161,3075,0.0523577235772358,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_086","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2311,117,2471,0.047349251315257,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.47,15.29,2311,117,2471,0.047349251315257,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_087","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1432,79,1529,0.0516677567037279,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.54,15.32,1432,79,1529,0.0516677567037279,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_088","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",2351,142,2518,0.0563939634630659,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",18.79,15.31,2351,142,2518,0.0563939634630659,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, many samples","UPN_Tr2_096","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1512,35,1554,0.0225225225225225,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",20.03,16.26,1511,35,1553,0.0225370251126851,1,0,1,0,1,23,23,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_097","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1710,35,1759,0.0198976691301876,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",19.56,15.57,1710,35,1759,0.0198976691301876,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, many samples","UPN_Tr2_107","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1492,40,1544,0.0259067357512953,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",19.6,15.45,1492,40,1544,0.0259067357512953,0,0,0,"NA",1,23,23,"Artifact (5)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_108","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",3366,60,3447,0.0174064403829417,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",19.97,15.4,3360,60,3441,0.01743679163034,6,0,6,0,1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_109","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1514,27,1547,0.0174531351001939,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",19.71,15.63,1507,27,1540,0.0175324675324675,7,0,7,0,1,23,23,"Artifact (7)"]
["low bq, bad alignment, low freq, many artifacts, many samples","UPN_Tr2_110","X",15841143,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys409Asn/c.1227A>C",1083,20,1107,0.01806684733514,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.315,"Tolerated",19.78,15.1,1083,20,1107,0.01806684733514,0,0,0,"NA",1,23,23,"Artifact (7)"]
["low bq, bad alignment, many samples","UPN_Tr2_076","X",15841147,"A","C","ZRSR2","ENST00000307771","missense_variant","Aca/Cca|p.Thr411Pro/c.1231A>C",1115,26,1156,0.0224913494809689,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.909,"Tolerated",23.49,16.54,1115,26,1156,0.0224913494809689,0,0,0,"NA",1,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_006","X",15841162,"G","A","ZRSR2","ENST00000307771","missense_variant","Gag/Aag|p.Glu416Lys/c.1246G>A",2562,34,2605,0.0130518234165067,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.787,"Tolerated",33.7,33.76,2547,34,2590,0.0131274131274131,15,0,15,0,1,1,1,"Artifact (5)"]
["low bq, low freq, many artifacts","UPN_Tr2_047","X",15841169,"A","G","ZRSR2","ENST00000307771","missense_variant","cAc/cGc|p.His418Arg/c.1253A>G",5560,66,5667,0.011646373742721,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.399,"Tolerated",28.2,26.32,2731,40,2807,0.0142500890630566,2829,26,2860,0.00909090909090909,0.0822118507211964,3,4,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_076","X",15841169,"A","G","ZRSR2","ENST00000307771","missense_variant","cAc/cGc|p.His418Arg/c.1253A>G",2213,24,2306,0.01040763226366,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.399,"Tolerated",26.01,22.25,1067,17,1142,0.0148861646234676,1146,7,1164,0.00601374570446735,0.0381258361298376,3,4,"Artifact (5)"]
["low bq, low freq, many artifacts","UPN_Tr2_087","X",15841169,"A","G","ZRSR2","ENST00000307771","missense_variant","cAc/cGc|p.His418Arg/c.1253A>G",2963,32,3068,0.0104302477183833,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.399,"Tolerated",26.05,21.19,1428,26,1515,0.0171617161716172,1535,6,1553,0.00386349001931745,0.000234859140751718,3,4,"Artifact (6)"]
["low bq, low freq, many artifacts","UPN_Tr2_072","X",15841169,"A","T","ZRSR2","ENST00000307771","missense_variant","cAc/cTc|p.His418Leu/c.1253A>T",2167,23,2238,0.0102770330652368,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.908,"Deleterious",26.14,22.09,1045,15,1104,0.0135869565217391,1122,8,1134,0.00705467372134039,0.141049199039566,1,4,"Artifact (4)"]
["low bq, bad alignment, many samples","UPN_Tr2_075","X",15841173,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn419Lys/c.1257T>A",1081,34,1180,0.0288135593220339,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.293,"Tolerated",21.45,16.09,1044,34,1143,0.0297462817147857,37,0,37,0,0.624508213009567,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_091","X",15841174,"T","A","ZRSR2","ENST00000307771","missense_variant","Tca/Aca|p.Ser420Thr/c.1258T>A",2133,25,2164,0.0115526802218115,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.058,"Tolerated",32.14,25.16,1056,14,1073,0.0130475302889096,1077,11,1091,0.0100824931255729,0.551930667711661,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_024","X",15841180,"A","T","ZRSR2","ENST00000307771","missense_variant","Agc/Tgc|p.Ser422Cys/c.1264A>T",1435,20,1464,0.0136612021857923,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.491,"Tolerated",28.21,22.35,715,8,728,0.010989010989011,720,12,736,0.016304347826087,0.500614709727258,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_006","X",15841186,"G","A","ZRSR2","ENST00000307771","missense_variant","Gga/Aga|p.Gly424Arg/c.1270G>A",5117,54,5187,0.0104106419895894,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.16,"Tolerated",32.52,27.19,2539,27,2577,0.010477299185099,2578,27,2610,0.0103448275862069,1,2,2,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_063","X",15841186,"G","A","ZRSR2","ENST00000307771","missense_variant","Gga/Aga|p.Gly424Arg/c.1270G>A",1866,22,1897,0.0115972588297312,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.16,"Tolerated",30.11,27.45,915,11,934,0.0117773019271949,951,11,963,0.0114226375908619,1,2,2,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_056","X",15841187,"GA","G","ZRSR2","ENST00000307771","frameshift_variant","aga/|p.Arg425fs/c.1273delA",2815,39,2881,0.013536966331135,0,0,0,1,1,0,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.92,"NA",1389,17,1420,0.0119718309859155,1426,22,1461,0.0150581793292266,0.521306825933285,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_054","X",15841192,"A","G","ZRSR2","ENST00000307771","missense_variant","Aat/Gat|p.Asn426Asp/c.1276A>G",2884,31,2945,0.0105263157894737,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.093,"Tolerated",29.26,33,1414,15,1451,0.0103376981392143,1470,16,1494,0.0107095046854083,1,1,1,"Artifact (4)"]
["inspected, not in 2nd Illumina","UPN_Tr2_004","X",15841211,"ACCGCAGCCGGGGCCGGGGCAGCCGGAGCCGGAGCCGGAGCCGGAGCCGCAGGAGCCG","A","ZRSR2","ENST00000307771","inframe_deletion","ggccggggcagccggagccggagccggagccggagccgcaggagccgccgcagccgg/|p.Gly436_Arg454del/c.1306_1362delGGCCGGGGCAGCCGGAGCCGGAGCCGGAGCCGGAGCCGCAGGAGCCGCCGCAGCCGG",192,"NA",192,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-15.792,"Deleterious",35.02,"NA",0,"NA",0,"NA",192,"NA",192,"NA","NA",1,1,"Artifact (0)"]
["low freq, neutral effect","UPN_Tr2_046","X",15841232,"G","A","ZRSR2","ENST00000307771","missense_variant","aGc/aAc|p.Ser439Asn/c.1316G>A",2220,24,2244,0.0106951871657754,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.568,"Tolerated",35.13,34.58,12,0,12,0,2208,24,2232,0.010752688172043,1,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_041","X",15841234,"C","T","ZRSR2","ENST00000307771","missense_variant","Cgg/Tgg|p.Arg440Trp/c.1318C>T",3224,45,3276,0.0137362637362637,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.054,"Tolerated",33.8,29.47,0,0,0,"NA",3224,45,3276,0.0137362637362637,1,1,1,"Artifact (3)"]
["low freq, neutral effect","UPN_Tr2_044","X",15841247,"G","A","ZRSR2","ENST00000307771","missense_variant","cGg/cAg|p.Arg444Gln/c.1331G>A",929,29,961,0.0301768990634755,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.322,"Tolerated",34.09,35.07,0,0,0,"NA",929,29,961,0.0301768990634755,1,1,1,"Artifact (2)"]
["low freq, neutral effect","UPN_Tr2_081","X",15841253,"G","A","ZRSR2","ENST00000307771","missense_variant","cGg/cAg|p.Arg446Gln/c.1337G>A",2305,24,2333,0.0102871838834119,0,0,0,0,1,0,0,1,2,0,"NO","NO","NO","O","NO","rs375322183","NO","NO","NO","NO",-0.878,"Tolerated",33.64,35.08,0,0,0,"NA",2305,24,2333,0.0102871838834119,1,1,1,"Artifact (3)"]
["low freq, neutral effect","UPN_Tr2_044","X",15841258,"C","A","ZRSR2","ENST00000307771","missense_variant","Cgc/Agc|p.Arg448Ser/c.1342C>A",919,39,961,0.040582726326743,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.584,"Tolerated",34.67,35.51,0,0,0,"NA",919,39,961,0.040582726326743,1,1,1,"Artifact (2)"]
["low freq, many artifacts","UPN_Tr2_027","X",15841267,"C","T","ZRSR2","ENST00000307771","missense_variant","Cgc/Tgc|p.Arg451Cys/c.1351C>T",2149,22,2181,0.010087116001834,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.361,"Tolerated",35.46,32.73,5,18,31,0.580645161290323,2144,4,2150,0.00186046511627907,1.46053248316104E-036,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_056","X",15841268,"G","A","ZRSR2","ENST00000307771","missense_variant","cGc/cAc|p.Arg451His/c.1352G>A",1498,20,1520,0.0131578947368421,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.28,"Tolerated",35.04,35.55,57,0,57,0,1441,20,1463,0.0136705399863295,1,1,1,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_005","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",1554,28,1588,0.017632241813602,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.53,34.93,1133,14,1152,0.0121527777777778,421,14,436,0.0321100917431193,2,6,6,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_008","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",9227,127,9392,0.0135221465076661,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.64,35.6,6169,62,6256,0.00991048593350384,3058,65,3136,0.0207270408163265,2,6,6,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_011","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",11801,228,12095,0.0188507647788342,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.58,35.14,8522,112,8682,0.0129002533978346,3279,116,3413,0.033987694110753,2,6,6,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_090","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",3837,69,3931,0.0175527855507504,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.83,34.81,3093,34,3149,0.0107970784375992,744,35,782,0.0447570332480818,2,6,6,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_059","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",3092,33,3150,0.0104761904761905,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.46,35.64,397,15,417,0.0359712230215827,2695,18,2733,0.00658616904500549,2,6,6,"Artifact (5)"]
["low freq, many artifacts","UPN_Tr2_013","X",15841283,"A","C","ZRSR2","ENST00000307771","missense_variant","cAa/cCa|p.Gln456Pro/c.1367A>C",1798,30,1836,0.0163398692810458,0,0,0,0,1,1,0,1,3,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.153,"Tolerated",35.66,35,1256,15,1275,0.0117647058823529,542,15,561,0.0267379679144385,2,6,6,"Artifact (5)"]
["low freq, neutral effect","UPN_Tr2_056","X",15841313,"G","A","ZRSR2","ENST00000307771","missense_variant","aGg/aAg|p.Arg466Lys/c.1397G>A",1493,23,1520,0.0151315789473684,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.611,"Tolerated",35.35,35.83,57,0,57,0,1436,23,1463,0.0157211209842789,2,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_006","X",15841333,"G","C","ZRSR2","ENST00000307771","missense_variant","Gac/Cac|p.Asp473His/c.1417G>C",1339,22,1363,0.0161408657373441,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-1.016,"Tolerated",35.63,35.82,1339,22,1363,0.0161408657373441,0,0,0,"NA",1,1,1,"Artifact (4)"]
["low freq, many artifacts","UPN_Tr2_045","X",15841337,"G","T","ZRSR2","ENST00000307771","missense_variant","aGa/aTa|p.Arg474Ile/c.1421G>T",1741,21,1763,0.0119115144639818,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-2.729,"Deleterious",35.25,35.05,1741,21,1763,0.0119115144639818,0,0,0,"NA",1,1,1,"Artifact (3)"]
["low freq, many artifacts","UPN_Tr2_006","X",15841345,"C","T","ZRSR2","ENST00000307771","stop_gained","Cag/Tag|p.Gln477*/c.1429C>T",2678,32,2714,0.0117907148120855,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.06,33.88,1346,16,1363,0.0117388114453412,1332,16,1351,0.0118430792005922,1,1,1,"Artifact (3)"]
["inspected","UPN_Tr2_056","X",15841360,"AA","T","ZRSR2","ENST00000307771","frameshift_variant+stop_gained","aaa/Ta|p.Lys482fs/c.1444_1445delAAinsT",97,"NA",99,"NA",0,0,0,0,0,0,0,1,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.39,"NA",56,"NA",57,"NA",41,"NA",42,"NA","NA",1,1,"Artifact (1)"]
["low freq, many artifacts","UPN_Tr2_006","X",15841361,"A","G","ZRSR2","ENST00000307771","missense_variant","aAa/aGa|p.Lys482Arg/c.1445A>G",2678,32,2714,0.0117907148120855,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",0.144,"Tolerated",33.8,35.75,1345,17,1362,0.0124816446402349,1333,15,1352,0.011094674556213,0.85927733486874,1,1,"Artifact (4)"]
["low bq, low freq, many artifacts","UPN_Tr2_044","X",15841362,"A","T","ZRSR2","ENST00000307771","missense_variant","aaA/aaT|p.Lys482Asn/c.1446A>T",3984,55,4066,0.0135268076733891,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO",-0.378,"Tolerated",32.68,28.95,2018,22,2051,0.0107264748902974,1966,33,2015,0.0163771712158809,0.135293998579101,1,1,"Artifact (4)"]
[{"$nulls":14},{"$f":"SUM(O2:O8367)","v":141},{"$f":"SUM(P2:P8367)","v":684},{"$f":"SUM(Q2:Q8367)","v":98},{"$f":"SUM(R2:R8367)","v":1624},{"$f":"SUM(S2:S8367)","v":8075},{"$f":"SUM(T2:T8367)","v":3373},{"$f":"SUM(U2:U8367)","v":102},{"$f":"SUM(V2:V8367)","v":3436}]

{"sheet":"TN Mutations Filter 1","index":8,"n_rows":32062,"n_cols":47,"rows_kept":1125,"cut":true,"hidden":false,"merged":[],"bounds":{"rows_first":500,"rows_last":125,"rows_between":500,"halvings":2}}
["Sample","Chr","Pos","Ref","Alt","Gene","ENST","Type","Mutation","Nr_Ref","Nr_Alt","DP","VAF","GATK","Platypus","VarScan","LoFreq","FreeBayes","SNVer","SAMtools","VarDict","Called","ESP6500","G1000","Cosmic","Cosmic_location","Cosmic_occurence","dbSNP_SNPs","dbSNP_SNVs","PM_flag","ExAC","ClinVar_clinical","ClinVar_noimpact","Provean_Prediction","Provean_Score","BQ_Ref","BQ_Alt","Nr_Ref_fwd","Nr_Alt_fwd","DP_fwd","VAF_fwd","Nr_Ref_rev","Nr_Alt_rev","DP_rev","VAF_rev","bq","alignment"]
["UPN_Tr2_058",1,115256533,"C","A","NRAS","ENST00000369535","stop_gained","Gga/Tga|p.Gly60*/c.178G>T",3390,40,3441,0.01162452775356,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.09,14.55,3349,40,3400,0.0117647058823529,41,0,41,0,"low bq","NA"]
["UPN_Tr2_015",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1135,28,1163,0.0240756663800516,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.97,15.14,1121,27,1148,0.0235191637630662,14,1,15,0.0666666666666667,"low bq","NA"]
["UPN_Tr2_022",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",800,31,837,0.037037037037037,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.33,15.65,787,31,821,0.0377588306942753,13,0,16,0,"low bq","NA"]
["UPN_Tr2_025",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",904,25,933,0.0267952840300107,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.61,15.96,893,23,919,0.0250272034820457,11,2,14,0.142857142857143,"low bq","NA"]
["UPN_Tr2_026",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",773,22,798,0.0275689223057644,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.84,14.32,764,21,787,0.0266836086404066,9,1,11,0.0909090909090909,"low bq","NA"]
["UPN_Tr2_027",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1082,27,1112,0.0242805755395683,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.17,15,1065,26,1091,0.0238313473877177,17,1,21,0.0476190476190476,"low bq","NA"]
["UPN_Tr2_028",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",785,20,812,0.0246305418719212,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.26,16.65,777,20,802,0.0249376558603491,8,0,10,0,"low bq","NA"]
["UPN_Tr2_029",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",901,36,942,0.0382165605095541,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.57,17.17,887,36,925,0.0389189189189189,14,0,17,0,"low bq","NA"]
["UPN_Tr2_030",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1000,22,1026,0.0214424951267057,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.37,16.14,982,21,1006,0.0208747514910537,18,1,20,0.05,"low bq","NA"]
["UPN_Tr2_035",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1519,32,1558,0.0205391527599487,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.28,18.03,1487,32,1524,0.020997375328084,32,0,34,0,"low bq","NA"]
["UPN_Tr2_036",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1669,51,1724,0.0295823665893271,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.47,15.82,1623,50,1675,0.0298507462686567,46,1,49,0.0204081632653061,"low bq","NA"]
["UPN_Tr2_037",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1296,21,1327,0.0158251695553881,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.14,15.81,1281,19,1309,0.014514896867838,15,2,18,0.111111111111111,"low bq","NA"]
["UPN_Tr2_038",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1535,22,1573,0.013986013986014,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.27,15,1506,21,1537,0.0136629798308393,29,1,36,0.0277777777777778,"low bq","NA"]
["UPN_Tr2_008",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1018,22,1042,0.0211132437619962,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.49,14.32,1010,22,1033,0.021297192642788,8,0,9,0,"low bq","NA"]
["UPN_Tr2_058",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",3339,71,3422,0.0207481005260082,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.28,15.89,3301,69,3381,0.0204081632653061,38,2,41,0.0487804878048781,"low bq","NA"]
["UPN_Tr2_040",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1473,41,1518,0.0270092226613966,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.06,15.63,1448,38,1488,0.0255376344086022,25,3,30,0.1,"low bq","NA"]
["UPN_Tr2_071",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",727,23,753,0.0305444887118194,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.25,15.57,704,21,726,0.0289256198347107,23,2,27,0.0740740740740741,"low bq","NA"]
["UPN_Tr2_075",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1157,25,1189,0.0210260723296888,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.31,15.24,1124,25,1155,0.0216450216450216,33,0,34,0,"low bq","NA"]
["UPN_Tr2_085",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",954,24,991,0.024217961654894,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.8,18.04,939,23,969,0.0237358101135191,15,1,22,0.0454545454545455,"low bq","NA"]
["UPN_Tr2_087",1,115256541,"T","A","NRAS","ENST00000369535","missense_variant","gAt/gTt|p.Asp57Val/c.170A>T",1089,25,1126,0.022202486678508,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.85,14.52,1057,25,1087,0.0229990800367985,32,0,39,0,"low bq","NA"]
["UPN_Tr2_059",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",29195,473,29780,0.0158831430490262,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.63,14.96,29193,473,29778,0.0158842098193297,2,0,2,0,"low bq","NA"]
["UPN_Tr2_060",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",16877,245,17199,0.0142450142450142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.97,14.83,16877,245,17199,0.0142450142450142,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_061",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",14240,230,14535,0.0158238734090127,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.64,15.2,14240,230,14535,0.0158238734090127,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_062",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",13452,241,13755,0.0175209014903671,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.3,14.61,13452,241,13755,0.0175209014903671,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_063",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",14191,247,14510,0.0170227429359063,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.68,14.68,14191,247,14510,0.0170227429359063,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_064",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",19089,338,19521,0.0173146867476051,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.6,14.97,19089,338,19521,0.0173146867476051,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_065",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",19815,356,20267,0.0175655005674249,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.73,15.08,19815,356,20267,0.0175655005674249,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_066",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",27479,437,28046,0.0155815446052913,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.91,14.62,27479,437,28046,0.0155815446052913,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_067",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",24632,387,25115,0.0154091180569381,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.11,14.96,24632,387,25115,0.0154091180569381,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_068",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",16764,329,17158,0.0191747289893927,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.23,14.58,16764,329,17158,0.0191747289893927,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_069",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",18141,358,18578,0.0192701044245882,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.57,14.76,18133,358,18570,0.0192784060312332,8,0,8,0,"low bq","NA"]
["UPN_Tr2_070",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",12676,207,12938,0.015999381666409,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.42,14.86,12676,207,12938,0.015999381666409,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_071",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",11671,206,11951,0.0172370512927788,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.56,14.93,11671,206,11951,0.0172370512927788,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_072",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",14555,283,14903,0.0189894652083473,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.54,14.76,14555,283,14903,0.0189894652083473,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_073",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",12126,186,12357,0.015052197135227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.82,14.89,12126,186,12357,0.015052197135227,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_074",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",11587,216,11846,0.0182340030390005,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,14.69,11587,216,11846,0.0182340030390005,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_075",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",18039,287,18388,0.0156080052207962,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.07,15.04,18039,287,18388,0.0156080052207962,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_076",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",15972,285,16320,0.0174632352941176,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.32,14.61,15972,285,16320,0.0174632352941176,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_077",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",16669,310,17039,0.0181935559598568,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.58,14.68,16668,310,17038,0.0181946237821341,1,0,1,0,"low bq","NA"]
["UPN_Tr2_078",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",15739,277,16094,0.0172113831241456,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.35,14.92,15739,277,16094,0.0172113831241456,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_079",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",9917,177,10140,0.0174556213017751,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.78,14.95,9917,177,10140,0.0174556213017751,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_080",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",16442,294,16814,0.0174854288093256,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.54,15.05,16442,294,16814,0.0174854288093256,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_081",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",22485,369,22961,0.016070728626802,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.73,14.83,22485,369,22961,0.016070728626802,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_082",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",23183,352,23652,0.0148824623710468,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.89,14.89,23183,352,23652,0.0148824623710468,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_083",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",18188,327,18595,0.0175853724119387,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.28,14.85,18188,327,18595,0.0175853724119387,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_084",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",21278,365,21728,0.0167986008836524,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.14,15.27,21278,365,21728,0.0167986008836524,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_085",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",25810,419,26358,0.0158965020107747,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.58,15.33,25810,419,26358,0.0158965020107747,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_086",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",23752,464,24348,0.0190570067356662,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.34,14.74,23752,464,24348,0.0190570067356662,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_087",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",21152,392,21651,0.0181053992887165,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.54,14.88,21137,392,21635,0.0181187889993067,15,0,16,0,"low bq","NA"]
["UPN_Tr2_088",1,115258741,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val14Gly/c.41T>G",15649,244,15966,0.0152824752599273,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.14,14.73,15649,244,15966,0.0152824752599273,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_059",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",56968,1235,58597,0.021076164308753,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.05,14.6,28544,1072,29764,0.0360166644268244,28424,163,28833,0.00565324454617972,"low bq","NA"]
["UPN_Tr2_060",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",32938,676,33826,0.0199846272098386,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.17,14.99,16534,578,17199,0.0336066050351765,16404,98,16627,0.00589402778613099,"low bq","NA"]
["UPN_Tr2_061",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",27794,602,28593,0.0210541041513657,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.87,14.72,13939,517,14532,0.0355766584090283,13855,85,14061,0.00604508925396487,"low bq","NA"]
["UPN_Tr2_062",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",26313,582,27057,0.0215101452489189,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.66,14.65,13192,504,13751,0.0366518798632827,13121,78,13306,0.00586201713512701,"low bq","NA"]
["UPN_Tr2_063",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",27689,606,28530,0.0212407991587802,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.09,14.55,13873,538,14506,0.0370881014752516,13816,68,14024,0.00484883057615516,"low bq","NA"]
["UPN_Tr2_064",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",37312,835,38357,0.0217691686002555,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.98,14.94,18695,729,19510,0.0373654536135315,18617,106,18847,0.00562423727914257,"low bq","NA"]
["UPN_Tr2_065",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",38794,865,39877,0.0216917019835996,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.11,14.89,19414,765,20261,0.0377572676570752,19380,100,19616,0.0050978792822186,"low bq","NA"]
["UPN_Tr2_066",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",53696,1131,55140,0.0205114254624592,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.19,14.96,26944,976,28038,0.034809900848848,26752,155,27102,0.0057191351191794,"low bq","NA"]
["UPN_Tr2_067",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",48112,962,49362,0.019488675499372,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.37,14.8,24172,825,25110,0.0328554360812425,23940,137,24252,0.00564901863763813,"low bq","NA"]
["UPN_Tr2_068",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",32746,777,33712,0.0230481727574751,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.68,14.8,16397,681,17152,0.0397038246268657,16349,96,16560,0.00579710144927536,"low bq","NA"]
["UPN_Tr2_069",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",35552,774,36523,0.0211921255099526,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.97,14.73,17809,671,18559,0.0361549652459723,17743,103,17964,0.00573368960142507,"low bq","NA"]
["UPN_Tr2_070",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",24714,579,25463,0.0227388760161803,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.77,14.89,12361,497,12931,0.0384347691593844,12353,82,12532,0.00654324928183849,"low bq","NA"]
["UPN_Tr2_071",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",22822,511,23499,0.0217456061960083,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.12,15.03,11433,450,11949,0.0376600552347477,11389,61,11550,0.00528138528138528,"low bq","NA"]
["UPN_Tr2_072",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",28458,650,29315,0.0221729490022173,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.03,14.85,14228,579,14898,0.0388642770841724,14230,71,14417,0.00492474162447111,"low bq","NA"]
["UPN_Tr2_073",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",23661,497,24304,0.0204493087557604,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.14,14.7,11862,431,12351,0.0348959598413084,11799,66,11953,0.00552162636994897,"low bq","NA"]
["UPN_Tr2_074",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",22719,454,23285,0.0194975305990981,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.21,14.77,11408,392,11841,0.033105312051347,11311,62,11444,0.00541768612373296,"low bq","NA"]
["UPN_Tr2_075",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",35284,695,36196,0.0192010166869267,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.3,14.96,17696,607,18381,0.0330232305097655,17588,88,17815,0.00493965759191692,"low bq","NA"]
["UPN_Tr2_076",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",31165,779,32108,0.0242618662015697,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.76,15.01,15560,691,16315,0.042353662273981,15605,88,15793,0.00557208890014563,"low bq","NA"]
["UPN_Tr2_077",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",32614,713,33545,0.0212550305559696,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.89,15.06,16341,602,17036,0.0353369335524771,16273,111,16509,0.00672360530619662,"low bq","NA"]
["UPN_Tr2_078",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",30831,719,31705,0.022677811070809,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.68,14.69,15413,630,16094,0.0391450229899341,15418,89,15611,0.00570110819294087,"low bq","NA"]
["UPN_Tr2_079",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",19466,400,19986,0.0200140098068648,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.01,14.87,9742,348,10139,0.0343229115297367,9724,52,9847,0.00528079618157815,"low bq","NA"]
["UPN_Tr2_080",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",32114,779,33095,0.0235382988366823,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.93,14.97,16053,677,16804,0.040288026660319,16061,102,16291,0.00626112577496777,"low bq","NA"]
["UPN_Tr2_081",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",43966,901,45125,0.0199667590027701,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.19,14.78,22077,790,22955,0.0344151600958397,21889,111,22170,0.00500676589986468,"low bq","NA"]
["UPN_Tr2_082",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",45210,928,46414,0.0199939673374413,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.19,14.93,22719,823,23645,0.0348065130048636,22491,105,22769,0.0046115332249989,"low bq","NA"]
["UPN_Tr2_083",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",35513,834,36576,0.0228018372703412,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.64,14.96,17762,730,18587,0.0392747619303815,17751,104,17989,0.00578131080104508,"low bq","NA"]
["UPN_Tr2_084",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",41449,1001,42719,0.023432196446546,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.76,14.64,20735,887,21726,0.0408266593022185,20714,114,20993,0.00543038155575668,"low bq","NA"]
["UPN_Tr2_085",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",50323,1085,51778,0.0209548456873576,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.08,14.97,25245,955,26347,0.0362470110449007,25078,130,25431,0.00511187133813063,"low bq","NA"]
["UPN_Tr2_086",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",46455,1063,47786,0.0222450089984514,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.84,14.7,23286,949,24343,0.0389845130016843,23169,114,23443,0.00486285884912341,"low bq","NA"]
["UPN_Tr2_087",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",41310,914,42465,0.0215236076769104,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.99,14.96,20720,825,21632,0.0381379437869823,20590,89,20833,0.00427206835309365,"low bq","NA"]
["UPN_Tr2_088",1,115258756,"A","C","NRAS","ENST00000369535","missense_variant","gTt/gGt|p.Val9Gly/c.26T>G",30627,605,31418,0.0192564771786874,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.33,14.85,15381,510,15958,0.0319588920917408,15246,95,15460,0.00614489003880983,"low bq","NA"]
["UPN_Tr2_068",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",33153,387,33766,0.0114612331931529,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.36,15.18,16778,312,17153,0.0181892380341631,16375,75,16613,0.00451453680852345,"low bq","NA"]
["UPN_Tr2_069",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",35998,379,36583,0.0103600032802121,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.59,14.81,18181,322,18559,0.0173500727409882,17817,57,18024,0.0031624500665779,"low bq","NA"]
["UPN_Tr2_076",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",31621,363,32174,0.0112824019394542,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.37,14.92,15981,287,16316,0.0175900956116695,15640,76,15858,0.00479253373691512,"low bq","NA"]
["UPN_Tr2_081",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",44384,453,45201,0.010021902170306,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.66,15.19,22448,387,22956,0.0168583376894929,21936,66,22245,0.00296695886716116,"low bq","NA"]
["UPN_Tr2_083",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",36001,377,36642,0.0102887396976148,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.32,15.1,18203,301,18588,0.0161932429524424,17798,76,18054,0.00420959344189653,"low bq","NA"]
["UPN_Tr2_086",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",47031,545,47882,0.0113821477799591,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.43,15.21,23794,459,24343,0.0188555231483383,23237,86,23539,0.00365351119418837,"low bq","NA"]
["UPN_Tr2_087",1,115258759,"A","C","NRAS","ENST00000369535","missense_variant","gTg/gGg|p.Val8Gly/c.23T>G",41852,438,42546,0.0102947398110281,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.58,14.97,21194,366,21630,0.0169209431345354,20658,72,20916,0.00344234079173838,"low bq","NA"]
["UPN_Tr2_041",1,115258794,"A","T","NRAS","ENST00000369535","5_prime_UTR_premature_start_codon_gain_variant","|c.-13T>A",14659,173,14908,0.011604507646901,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.19,23.08,730,10,746,0.0134048257372654,13929,163,14162,0.0115096737748906,"low bq","NA"]
["UPN_Tr2_080",2,25457203,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val895Gly/c.2684T>G",2600,27,2647,0.0102002266717038,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.76,14.93,2600,27,2647,0.0102002266717038,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_059",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1358,23,1391,0.0165348670021567,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.67,15.13,1300,20,1328,0.0150602409638554,58,3,63,0.0476190476190476,"low bq","NA"]
["UPN_Tr2_060",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1766,22,1798,0.0122358175750834,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.75,14,1664,20,1692,0.0118203309692671,102,2,106,0.0188679245283019,"low bq","NA"]
["UPN_Tr2_061",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2000,32,2039,0.0156939676311918,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.7,15.78,1938,32,1973,0.0162189559047136,62,0,66,0,"low bq","NA"]
["UPN_Tr2_062",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2454,39,2500,0.0156,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.35,14.67,2332,35,2373,0.0147492625368732,122,4,127,0.031496062992126,"low bq","NA"]
["UPN_Tr2_063",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2195,35,2244,0.0155971479500891,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.25,15.23,2058,31,2099,0.0147689375893283,137,4,145,0.0275862068965517,"low bq","NA"]
["UPN_Tr2_064",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1926,32,1973,0.0162189559047136,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.58,14.22,1820,30,1862,0.0161117078410312,106,2,111,0.018018018018018,"low bq","NA"]
["UPN_Tr2_070",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1021,23,1046,0.0219885277246654,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.88,15.09,989,19,1010,0.0188118811881188,32,4,36,0.111111111111111,"low bq","NA"]
["UPN_Tr2_071",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2392,37,2438,0.0151763740771124,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.41,14.86,2303,33,2341,0.0140965399401965,89,4,97,0.0412371134020619,"low bq","NA"]
["UPN_Tr2_072",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2590,41,2644,0.0155068078668684,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.46,15.02,2477,34,2523,0.0134760206103845,113,7,121,0.0578512396694215,"low bq","NA"]
["UPN_Tr2_073",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2065,37,2109,0.0175438596491228,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.89,14.68,1968,34,2007,0.0169407075236672,97,3,102,0.0294117647058824,"low bq","NA"]
["UPN_Tr2_075",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2681,48,2733,0.017563117453348,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.78,15.56,2558,40,2601,0.0153787004998078,123,8,132,0.0606060606060606,"low bq","NA"]
["UPN_Tr2_076",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1656,39,1698,0.0229681978798587,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.57,14.97,1581,36,1620,0.0222222222222222,75,3,78,0.0384615384615385,"low bq","NA"]
["UPN_Tr2_077",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1453,20,1478,0.013531799729364,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,16.3,1390,18,1412,0.0127478753541076,63,2,66,0.0303030303030303,"low bq","NA"]
["UPN_Tr2_078",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1771,24,1804,0.0133037694013304,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.53,14.29,1693,23,1725,0.0133333333333333,78,1,79,0.0126582278481013,"low bq","NA"]
["UPN_Tr2_079",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1391,31,1431,0.0216631726065688,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.87,15.58,1345,29,1382,0.0209840810419682,46,2,49,0.0408163265306122,"low bq","NA"]
["UPN_Tr2_080",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2757,36,2807,0.012825080156751,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.19,14.56,2604,32,2647,0.0120891575368342,153,4,160,0.025,"low bq","NA"]
["UPN_Tr2_081",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",3913,69,4001,0.0172456885778555,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.67,14.97,3750,63,3828,0.0164576802507837,163,6,173,0.0346820809248555,"low bq","NA"]
["UPN_Tr2_083",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2490,36,2534,0.0142067876874507,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.31,16.22,2371,31,2410,0.0128630705394191,119,5,124,0.0403225806451613,"low bq","NA"]
["UPN_Tr2_084",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",2173,41,2221,0.0184601530841963,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.26,14.76,2055,40,2101,0.0190385530699667,118,1,120,0.00833333333333333,"low bq","NA"]
["UPN_Tr2_085",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1183,23,1212,0.018976897689769,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.26,14.3,1133,20,1159,0.0172562553925798,50,3,53,0.0566037735849057,"low bq","NA"]
["UPN_Tr2_087",2,25457213,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser892Ala/c.2674T>G",1823,31,1859,0.0166756320602474,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.41,14,1726,27,1757,0.0153671030165054,97,4,102,0.0392156862745098,"low bq","NA"]
["UPN_Tr2_072",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",4906,55,4988,0.0110264635124298,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.44,15.76,2505,5,2523,0.00198176773682124,2401,50,2465,0.0202839756592292,"low bq","NA"]
["UPN_Tr2_073",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",3919,41,3977,0.0103092783505155,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.47,14.44,1996,2,2007,0.000996512207274539,1923,39,1970,0.0197969543147208,"low bq","NA"]
["UPN_Tr2_077",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",2751,32,2801,0.0114244912531239,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.78,14,1401,1,1412,0.000708215297450425,1350,31,1389,0.0223182145428366,"low bq","NA"]
["UPN_Tr2_079",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",2700,30,2733,0.0109769484083425,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.57,14.43,1379,1,1382,0.000723589001447178,1321,29,1351,0.0214655810510733,"low bq","NA"]
["UPN_Tr2_081",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",7463,77,7576,0.0101636747624076,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.46,14.18,3806,1,3828,0.00026123301985371,3657,76,3748,0.0202774813233725,"low bq","NA"]
["UPN_Tr2_087",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",3425,36,3474,0.0103626943005181,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.4,16.42,1741,4,1755,0.00227920227920228,1684,32,1719,0.0186154741128563,"low bq","NA"]
["UPN_Tr2_088",2,25457226,"T","G","DNMT3A","ENST00000264709","missense_variant","agA/agC|p.Arg887Ser/c.2661A>C",2081,22,2113,0.0104117368670137,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.46,14.32,1058,1,1065,0.000938967136150235,1023,21,1048,0.0200381679389313,"low bq","NA"]
["UPN_Tr2_056",2,25457239,"A","T","DNMT3A","ENST00000264709","stop_gained","tTg/tAg|p.Leu883*/c.2648T>A",7965,95,8106,0.0117197137922527,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.61,22.79,4042,24,4092,0.00586510263929619,3923,71,4014,0.0176880916791231,"low bq","NA"]
["UPN_Tr2_059",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2567,46,2632,0.0174772036474164,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.13,14.76,1274,45,1326,0.0339366515837104,1293,1,1306,0.000765696784073507,"low bq","NA"]
["UPN_Tr2_060",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3300,45,3362,0.0133848899464604,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.42,15.73,1638,45,1690,0.0266272189349112,1662,0,1672,0,"low bq","NA"]
["UPN_Tr2_061",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3808,64,3904,0.0163934426229508,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.29,15.39,1885,64,1962,0.0326197757390418,1923,0,1942,0,"low bq","NA"]
["UPN_Tr2_062",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4593,68,4701,0.0144650074452244,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.25,14.94,2284,67,2367,0.0283058724123363,2309,1,2334,0.000428449014567267,"low bq","NA"]
["UPN_Tr2_063",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4048,66,4153,0.0158921261738502,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.2,14.7,2011,65,2093,0.031055900621118,2037,1,2060,0.000485436893203883,"low bq","NA"]
["UPN_Tr2_064",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3577,68,3668,0.0185387131952017,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.36,15.69,1781,66,1857,0.0355411954765751,1796,2,1811,0.00110436223081171,"low bq","NA"]
["UPN_Tr2_065",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",1543,34,1584,0.0214646464646465,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.42,15.35,759,34,795,0.0427672955974843,784,0,789,0,"low bq","NA"]
["UPN_Tr2_068",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2132,36,2186,0.0164684354986276,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.95,15.31,1060,35,1104,0.0317028985507246,1072,1,1082,0.000924214417744917,"low bq","NA"]
["UPN_Tr2_069",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3291,55,3365,0.0163447251114413,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.11,15.2,1636,54,1698,0.0318021201413428,1655,1,1667,0.000599880023995201,"low bq","NA"]
["UPN_Tr2_070",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",1947,27,1993,0.0135474159558455,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.32,15.89,973,26,1007,0.0258192651439921,974,1,986,0.00101419878296146,"low bq","NA"]
["UPN_Tr2_071",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4550,68,4630,0.0146868250539957,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.32,14.78,2266,66,2336,0.0282534246575342,2284,2,2294,0.000871839581517001,"low bq","NA"]
["UPN_Tr2_072",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4890,74,4991,0.0148266880384692,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.1,14.74,2434,73,2517,0.0290027810885975,2456,1,2474,0.000404203718674212,"low bq","NA"]
["UPN_Tr2_073",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3906,51,3976,0.0128269617706237,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.17,15.35,1941,51,1999,0.0255127563781891,1965,0,1977,0,"low bq","NA"]
["UPN_Tr2_074",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",1703,30,1743,0.0172117039586919,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.4,14,848,29,881,0.0329171396140749,855,1,862,0.00116009280742459,"low bq","NA"]
["UPN_Tr2_075",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",5038,78,5152,0.015139751552795,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.38,14.41,2503,77,2595,0.0296724470134875,2535,1,2557,0.000391083300743058,"low bq","NA"]
["UPN_Tr2_076",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3126,71,3210,0.0221183800623053,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.14,15.73,1545,69,1619,0.0426189005558987,1581,2,1591,0.00125707102451289,"low bq","NA"]
["UPN_Tr2_077",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2736,54,2805,0.0192513368983957,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.31,15.04,1354,53,1412,0.0375354107648725,1382,1,1393,0.000717875089734386,"low bq","NA"]
["UPN_Tr2_078",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3355,48,3430,0.0139941690962099,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.21,15.6,1671,46,1725,0.0266666666666667,1684,2,1705,0.00117302052785924,"low bq","NA"]
["UPN_Tr2_079",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2676,43,2733,0.0157336260519576,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.34,15.7,1330,42,1376,0.0305232558139535,1346,1,1357,0.000736919675755343,"low bq","NA"]
["UPN_Tr2_080",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",5142,84,5249,0.0160030481996571,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.9,15.23,2553,82,2643,0.0310253499810821,2589,2,2606,0.000767459708365311,"low bq","NA"]
["UPN_Tr2_081",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",7402,128,7575,0.0168976897689769,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.31,15.65,3676,127,3819,0.0332547787378895,3726,1,3756,0.000266240681576145,"low bq","NA"]
["UPN_Tr2_082",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2543,33,2583,0.0127758420441347,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.19,14.79,1267,31,1299,0.0238645111624326,1276,2,1284,0.00155763239875389,"low bq","NA"]
["UPN_Tr2_083",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4671,78,4779,0.0163214061519146,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.16,15.46,2320,77,2407,0.0319900290818446,2351,1,2372,0.000421585160202361,"low bq","NA"]
["UPN_Tr2_084",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",4083,66,4162,0.015857760691975,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.92,15.8,2030,64,2098,0.0305052430886559,2053,2,2064,0.000968992248062015,"low bq","NA"]
["UPN_Tr2_085",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2233,47,2294,0.0204882301656495,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.19,16.17,1107,43,1155,0.0372294372294372,1126,4,1139,0.00351185250219491,"low bq","NA"]
["UPN_Tr2_087",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",3405,52,3478,0.0149511213341001,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.11,14.73,1690,52,1752,0.0296803652968037,1715,0,1726,0,"low bq","NA"]
["UPN_Tr2_088",2,25457257,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val877Gly/c.2630T>G",2067,39,2116,0.0184310018903592,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.43,14.33,1024,38,1065,0.0356807511737089,1043,1,1051,0.000951474785918173,"low bq","NA"]
["UPN_Tr2_061",2,25457264,"T","G","DNMT3A","ENST00000264709","missense_variant","Act/Cct|p.Thr875Pro/c.2623A>C",3840,40,3904,0.0102459016393443,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.94,18.88,1911,36,1962,0.018348623853211,1929,4,1942,0.00205973223480947,"low bq","NA"]
["UPN_Tr2_051",2,25457283,"A","T","DNMT3A","ENST00000264709","missense_variant","ttT/ttA|p.Phe868Leu/c.2604T>A",5989,62,6088,0.0101839684625493,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.78,25.85,0,0,0,"NA",5989,62,6088,0.0101839684625493,"low bq","NA"]
["UPN_Tr2_032",2,25457284,"A","T","DNMT3A","ENST00000264709","missense_variant","tTt/tAt|p.Phe868Tyr/c.2603T>A",1710,20,1737,0.0115141047783535,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.81,17.3,0,0,0,"NA",1710,20,1737,0.0115141047783535,"low bq","NA"]
["UPN_Tr2_049",2,25457284,"A","T","DNMT3A","ENST00000264709","missense_variant","tTt/tAt|p.Phe868Tyr/c.2603T>A",7366,80,7486,0.0106866150146941,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.04,20.9,0,0,0,"NA",7366,80,7486,0.0106866150146941,"low bq","NA"]
["UPN_Tr2_001",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",15949,171,16181,0.0105679500648909,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.07,15.56,8139,3,8177,0.000366882719823896,7810,168,8004,0.0209895052473763,"low bq","NA"]
["UPN_Tr2_014",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",23353,398,23840,0.0166946308724832,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.19,15.15,12003,6,12061,0.000497471188127021,11350,392,11779,0.0332795653281263,"low bq","NA"]
["UPN_Tr2_015",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",31844,600,32625,0.0183908045977011,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.15,15.11,16424,3,16526,0.00018153213118722,15420,597,16099,0.0370830486365613,"low bq","NA"]
["UPN_Tr2_016",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",14721,247,15030,0.0164337990685296,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.31,14.95,7565,2,7601,0.000263123273253519,7156,245,7429,0.0329788666038498,"low bq","NA"]
["UPN_Tr2_017",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",10588,209,10858,0.0192484803831276,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.27,14.99,5461,1,5495,0.000181983621474067,5127,208,5363,0.0387842625396233,"low bq","NA"]
["UPN_Tr2_018",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",16723,274,17095,0.0160280783854928,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.22,14.7,8592,1,8648,0.000115633672525439,8131,273,8447,0.0323191665680123,"low bq","NA"]
["UPN_Tr2_019",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",16966,322,17352,0.01855693868142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.11,15.44,8729,7,8772,0.000797993616051072,8237,315,8580,0.0367132867132867,"low bq","NA"]
["UPN_Tr2_020",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",14750,241,15065,0.0159973448390309,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.25,15.04,7570,2,7611,0.000262777558796479,7180,239,7454,0.0320633217064663,"low bq","NA"]
["UPN_Tr2_021",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",17283,268,17648,0.0151858567543064,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.27,14.84,8855,1,8909,0.000112246043326973,8428,267,8739,0.0305526948163405,"low bq","NA"]
["UPN_Tr2_002",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",21610,247,21963,0.0112461867686564,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.92,15.45,11052,1,11118,8.99442345745638E-005,10558,246,10845,0.0226832641770401,"low bq","NA"]
["UPN_Tr2_003",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",4214,50,4284,0.011671335200747,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.87,14.88,2153,1,2167,0.000461467466543609,2061,49,2117,0.0231459612659424,"low bq","NA"]
["UPN_Tr2_022",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",23001,410,23540,0.0174171622769754,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,15.25,11833,3,11910,0.000251889168765743,11168,407,11630,0.0349957007738607,"low bq","NA"]
["UPN_Tr2_023",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",25501,459,26090,0.0175929474894596,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,14.94,13131,3,13209,0.000227117874176698,12370,456,12881,0.0354009781849235,"low bq","NA"]
["UPN_Tr2_041",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",31886,427,32526,0.0131279591711246,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.05,15.47,16392,8,16519,0.00048429081663539,15494,419,16007,0.0261760479790092,"low bq","NA"]
["UPN_Tr2_024",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",11808,208,12089,0.0172057242120936,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.3,14.37,6082,1,6123,0.000163318634656214,5726,207,5966,0.034696614146832,"low bq","NA"]
["UPN_Tr2_025",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",29011,459,29648,0.0154816513761468,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.21,15.08,14895,6,14999,0.000400026668444563,14116,453,14649,0.0309236125332787,"low bq","NA"]
["UPN_Tr2_026",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",27923,511,28565,0.0178890250306319,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,15.39,14373,9,14454,0.00062266500622665,13550,502,14111,0.0355750832683722,"low bq","NA"]
["UPN_Tr2_004",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",6730,85,6844,0.0124196376388077,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.04,15.58,3438,2,3458,0.000578368999421631,3292,83,3386,0.0245126993502658,"low bq","NA"]
["UPN_Tr2_027",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",28533,536,29237,0.0183329342955844,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.14,15.15,14682,10,14792,0.000676041103299081,13851,526,14445,0.0364139840775355,"low bq","NA"]
["UPN_Tr2_089",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",18487,302,18869,0.0160050877100005,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.96,16.51,9510,0,9554,0,8977,302,9315,0.0324208266237252,"low bq","NA"]
["UPN_Tr2_042",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",42008,637,42906,0.0148464084277257,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.03,15.5,21683,12,21843,0.000549375085839857,20325,625,21063,0.029672886103594,"low bq","NA"]
["UPN_Tr2_028",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",23760,459,24328,0.0188671489641565,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.12,15.24,12246,5,12313,0.00040607488020791,11514,454,12015,0.037786100707449,"low bq","NA"]
["UPN_Tr2_043",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",29026,400,29630,0.0134998312521093,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.1,15.42,14950,2,15067,0.000132740426096768,14076,398,14563,0.0273295337499142,"low bq","NA"]
["UPN_Tr2_044",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",20579,327,21031,0.0155484760591508,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,15.26,10591,2,10660,0.000187617260787992,9988,325,10371,0.0313373830874554,"low bq","NA"]
["UPN_Tr2_029",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",28666,530,29385,0.0180364131359537,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.22,14.77,14780,3,14887,0.000201518103042923,13886,527,14498,0.0363498413574286,"low bq","NA"]
["UPN_Tr2_030",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",24826,396,25335,0.0156305506216696,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.18,14.85,12789,1,12851,7.78149560345498E-005,12037,395,12484,0.0316404998397949,"low bq","NA"]
["UPN_Tr2_031",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",17647,339,18112,0.0187168727915194,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.18,14.94,9088,4,9164,0.000436490615451768,8559,335,8948,0.0374385337505588,"low bq","NA"]
["UPN_Tr2_005",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",6888,79,6998,0.0112889396970563,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.93,15.92,3530,1,3549,0.000281769512538743,3358,78,3449,0.0226152507973326,"low bq","NA"]
["UPN_Tr2_045",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",38625,574,39452,0.0145493257629524,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.01,15.05,19902,7,20054,0.0003490575446295,18723,567,19398,0.0292298175069595,"low bq","NA"]
["UPN_Tr2_032",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",10600,194,10868,0.0178505704821494,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.14,14.4,5467,2,5510,0.000362976406533575,5133,192,5358,0.0358342665173572,"low bq","NA"]
["UPN_Tr2_046",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",37806,624,38665,0.0161386266649425,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28,15.73,19516,13,19661,0.000661207466558161,18290,611,19004,0.0321511260787203,"low bq","NA"]
["UPN_Tr2_033",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19404,313,19821,0.0157913324252056,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.24,14.52,9969,0,10025,0,9435,313,9796,0.0319518170681911,"low bq","NA"]
["UPN_Tr2_034",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",7309,139,7489,0.0185605554813727,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.23,15.18,3762,3,3788,0.000791974656810982,3547,136,3701,0.0367468251823831,"low bq","NA"]
["UPN_Tr2_047",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",50622,733,51669,0.0141864560955312,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.1,15.77,26080,14,26269,0.00053294758079866,24542,719,25400,0.0283070866141732,"low bq","NA"]
["UPN_Tr2_048",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",42524,587,43365,0.0135362619624121,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.06,15.54,21872,8,22022,0.000363273090545818,20652,579,21343,0.0271283324743476,"low bq","NA"]
["UPN_Tr2_035",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",26676,491,27302,0.017984030473958,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.26,15.06,13723,4,13801,0.000289834069994928,12953,487,13501,0.0360714021183616,"low bq","NA"]
["UPN_Tr2_036",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",43947,872,45077,0.0193446768862169,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.17,15,22678,9,22834,0.000394149075939389,21269,863,22243,0.0387987231938138,"low bq","NA"]
["UPN_Tr2_006",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",12739,144,12933,0.011134307585247,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.04,15.35,6526,1,6560,0.000152439024390244,6213,143,6373,0.0224384120508395,"low bq","NA"]
["UPN_Tr2_049",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",45610,645,46494,0.0138727577751968,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28,15.61,23513,16,23669,0.00067598969115721,22097,629,22825,0.0275575027382256,"low bq","NA"]
["UPN_Tr2_050",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",37713,533,38478,0.0138520713134778,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.94,15.65,19423,6,19559,0.000306764149496396,18290,527,18919,0.0278555949045933,"low bq","NA"]
["UPN_Tr2_037",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",44581,845,45673,0.018501083791299,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.09,15.1,22967,8,23113,0.000346125557045818,21614,837,22560,0.0371010638297872,"low bq","NA"]
["UPN_Tr2_051",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",29315,358,29863,0.0119880788936142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.1,15.43,15067,8,15182,0.000526939797128178,14248,350,14681,0.023840337851645,"low bq","NA"]
["UPN_Tr2_052",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",30118,422,30767,0.0137159944095947,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.9,15.2,15518,3,15645,0.000191754554170662,14600,419,15122,0.0277079751355641,"low bq","NA"]
["UPN_Tr2_038",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",42873,846,43946,0.0192508988303827,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,15.18,22078,7,22219,0.000315045681623835,20795,839,21727,0.0386155474754913,"low bq","NA"]
["UPN_Tr2_039",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",36318,722,37262,0.0193763083033654,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.07,15.24,18705,8,18834,0.00042476372517787,17613,714,18428,0.0387453874538745,"low bq","NA"]
["UPN_Tr2_053",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",37288,582,38056,0.0152932520496111,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,15.61,19239,9,19355,0.000464996125032291,18049,573,18701,0.0306400727233838,"low bq","NA"]
["UPN_Tr2_054",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",25996,396,26542,0.0149197498304574,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.88,15.73,13420,9,13515,0.000665926748057714,12576,387,13027,0.0297075305135488,"low bq","NA"]
["UPN_Tr2_007",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",47671,564,48481,0.0116334234029826,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,15.29,24397,7,24551,0.000285120769011446,23274,557,23930,0.0232762223150857,"low bq","NA"]
["UPN_Tr2_008",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",62186,714,63210,0.0112956810631229,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.93,15.48,31844,7,32038,0.000218490542480804,30342,707,31172,0.0226806108045682,"low bq","NA"]
["UPN_Tr2_009",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",54895,622,55815,0.0111439577174595,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.98,15.72,28080,10,28277,0.000353644304558475,26815,612,27538,0.0222238361536786,"low bq","NA"]
["UPN_Tr2_010",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",38047,476,38736,0.0122883106154482,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.89,15.51,19465,3,19594,0.000153108094314586,18582,473,19142,0.0247100616445512,"low bq","NA"]
["UPN_Tr2_011",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",44531,477,45247,0.0105421353901916,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28,15.38,22778,4,22938,0.000174383119714012,21753,473,22309,0.02120220538796,"low bq","NA"]
["UPN_Tr2_055",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",41993,642,42945,0.0149493538246594,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.08,14.97,21649,7,21829,0.00032067433231023,20344,635,21116,0.0300719833301762,"low bq","NA"]
["UPN_Tr2_056",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",29290,438,29878,0.0146596157708013,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.11,15.27,15118,4,15204,0.000263088660878716,14172,434,14674,0.0295761210303939,"low bq","NA"]
["UPN_Tr2_090",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",20433,344,20860,0.0164908916586769,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.81,16.27,10523,3,10567,0.00028390271600265,9910,341,10293,0.0331293111823569,"low bq","NA"]
["UPN_Tr2_057",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",44810,621,45707,0.0135865403548691,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.05,15.47,23136,8,23295,0.00034342133505044,21674,613,22412,0.0273514188827414,"low bq","NA"]
["UPN_Tr2_058",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",41248,603,42104,0.0143216796503895,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.15,15.2,21264,6,21415,0.00028017744571562,19984,597,20689,0.0288559137706027,"low bq","NA"]
["UPN_Tr2_059",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",49291,1902,51422,0.0369880595853915,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.61,26085,9,26227,0.000343157814466008,23206,1893,25195,0.0751339551498313,"low bq","NA"]
["UPN_Tr2_012",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",26169,275,26573,0.010348850336808,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.04,15.48,13383,2,13468,0.000148500148500148,12786,273,13105,0.0208317436093094,"low bq","NA"]
["UPN_Tr2_060",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",33103,1258,34532,0.0364299779914282,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.7,16.91,17552,5,17658,0.000283157775512516,15551,1253,16874,0.0742562522223539,"low bq","NA"]
["UPN_Tr2_040",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",12017,235,12328,0.0190622972096042,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.27,14.89,6196,2,6242,0.000320410124959949,5821,233,6086,0.038284587578048,"low bq","NA"]
["UPN_Tr2_013",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",12539,148,12757,0.0116014737007133,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.97,15.09,6428,2,6476,0.000308832612723904,6111,146,6281,0.0232447062569655,"low bq","NA"]
["UPN_Tr2_091",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",16905,276,17238,0.0160111381830839,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.96,16.53,8705,3,8738,0.00034332799267567,8200,273,8500,0.0321176470588235,"low bq","NA"]
["UPN_Tr2_092",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",14576,247,14861,0.0166206850144674,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,18.13,7485,18,7526,0.00239170874302418,7091,229,7335,0.0312201772324472,"low bq","NA"]
["UPN_Tr2_093",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",17513,297,17910,0.0165829145728643,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,15.8,9007,0,9058,0,8506,297,8852,0.0335517397198373,"low bq","NA"]
["UPN_Tr2_061",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40109,1661,41994,0.0395532695146926,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.91,21270,16,21416,0.000747104968248039,18839,1645,20578,0.0799397414714744,"low bq","NA"]
["UPN_Tr2_062",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",38797,1696,40700,0.0416707616707617,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.7,17.58,20656,8,20777,0.000385041151273042,18141,1688,19923,0.0847261958540381,"low bq","NA"]
["UPN_Tr2_063",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40152,1568,41948,0.0373796128540097,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.74,17.94,21259,11,21401,0.000513994673146115,18893,1557,20547,0.0757774857643452,"low bq","NA"]
["UPN_Tr2_064",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",57348,2299,59929,0.0383620617730982,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.74,17.69,30395,20,30576,0.00065410779696494,26953,2279,29353,0.0776411269716894,"low bq","NA"]
["UPN_Tr2_065",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",44282,1744,46284,0.0376804079163426,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.73,17.51,23485,15,23646,0.000634356762243085,20797,1729,22638,0.0763760049474335,"low bq","NA"]
["UPN_Tr2_066",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",56445,2261,59034,0.0382999627333401,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.37,29958,11,30156,0.000364769863377106,26487,2250,28878,0.0779139829628091,"low bq","NA"]
["UPN_Tr2_067",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",56902,2202,59378,0.0370844420492438,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.75,17.71,30185,11,30350,0.000362438220757825,26717,2191,29028,0.0754788480088191,"low bq","NA"]
["UPN_Tr2_068",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40465,1727,42421,0.0407109686240305,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.68,17.58,21534,7,21670,0.000323027226580526,18931,1720,20751,0.0828875716832924,"low bq","NA"]
["UPN_Tr2_069",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40800,1732,42787,0.0404795849206535,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.75,17.64,21729,8,21876,0.000365697568111172,19071,1724,20911,0.082444646358376,"low bq","NA"]
["UPN_Tr2_070",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",26673,1232,28056,0.0439121756487026,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.63,17.71,14249,8,14344,0.000557724484104852,12424,1224,13712,0.0892648774795799,"low bq","NA"]
["UPN_Tr2_071",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",22182,889,23173,0.0383636128252708,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.8,18.09,11782,8,11847,0.000675276441293154,10400,881,11326,0.0777856259932898,"low bq","NA"]
["UPN_Tr2_072",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",33027,1323,34516,0.038330049831962,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.79,17.87,17563,12,17667,0.000679232467311938,15464,1311,16849,0.0778087720339486,"low bq","NA"]
["UPN_Tr2_073",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",25710,1031,26902,0.0383242881570144,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.73,17.43,13614,5,13712,0.000364644107351225,12096,1026,13190,0.0777862016679303,"low bq","NA"]
["UPN_Tr2_074",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",26962,1076,28180,0.0381831085876508,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.68,17.7,14251,15,14350,0.00104529616724739,12711,1061,13830,0.0767172812725958,"low bq","NA"]
["UPN_Tr2_075",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",34055,1357,35548,0.0381737369190953,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.95,17988,6,18075,0.00033195020746888,16067,1351,17473,0.0773192926229039,"low bq","NA"]
["UPN_Tr2_076",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",30385,1296,31841,0.0407022392512798,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.67,17.66,16169,3,16258,0.000184524541764055,14216,1293,15583,0.082975036899185,"low bq","NA"]
["UPN_Tr2_077",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40110,1699,42019,0.0404340893405364,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.64,17.55,21304,10,21436,0.000466504944952417,18806,1689,20583,0.0820580090365836,"low bq","NA"]
["UPN_Tr2_078",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",31139,1298,32597,0.0398196153020217,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.63,17.58,16523,8,16627,0.000481145125398448,14616,1290,15970,0.0807764558547276,"low bq","NA"]
["UPN_Tr2_079",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19104,772,19951,0.0386948022655506,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.47,10127,4,10174,0.000393159032828779,8977,768,9777,0.0785517029763731,"low bq","NA"]
["UPN_Tr2_080",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",30624,1295,32118,0.0403200697428233,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.65,17.67,16262,14,16386,0.000854387892103015,14362,1281,15732,0.0814263920671243,"low bq","NA"]
["UPN_Tr2_081",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",44166,1609,45990,0.0349858664927158,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.87,23346,9,23477,0.000383353920858713,20820,1600,22513,0.0710700484164705,"low bq","NA"]
["UPN_Tr2_082",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",46815,1752,48830,0.0358795822240426,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.72,17.67,24802,7,24966,0.000280381318593287,22013,1745,23864,0.0731226952732149,"low bq","NA"]
["UPN_Tr2_083",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",36678,1575,38409,0.0410060142154183,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.7,17.66,19499,6,19593,0.000306231817485837,17179,1569,18816,0.0833864795918367,"low bq","NA"]
["UPN_Tr2_084",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",43742,1824,45777,0.0398453371780589,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.73,17.35,23262,17,23406,0.000726309493292318,20480,1807,22371,0.0807742166197309,"low bq","NA"]
["UPN_Tr2_085",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",40842,1676,42711,0.039240476692187,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.73,17.58,21698,6,21813,0.000275065328015404,19144,1670,20898,0.0799119532969662,"low bq","NA"]
["UPN_Tr2_086",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",33913,1420,35480,0.0400225479143179,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.7,17.56,18031,3,18118,0.000165581189976819,15882,1417,17362,0.0816150213109089,"low bq","NA"]
["UPN_Tr2_087",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",43424,1672,45369,0.0368533580197933,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.74,17.53,22980,12,23150,0.000518358531317495,20444,1660,22219,0.0747108330707953,"low bq","NA"]
["UPN_Tr2_088",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",33581,1295,35030,0.0369683128746788,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.74,17.46,17777,11,17881,0.000615178122028969,15804,1284,17149,0.0748731704472564,"low bq","NA"]
["UPN_Tr2_094",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",20935,369,21389,0.0172518584319043,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.86,16.43,10753,9,10804,0.000833024805627545,10182,360,10585,0.0340103920642418,"low bq","NA"]
["UPN_Tr2_095",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",21007,368,21467,0.0171425909535566,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.87,16.54,10804,2,10852,0.000184297825285662,10203,366,10615,0.0344795101271785,"low bq","NA"]
["UPN_Tr2_096",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",18016,281,18387,0.0152825365747539,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.94,16.25,9261,0,9307,0,8755,281,9080,0.0309471365638767,"low bq","NA"]
["UPN_Tr2_097",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",22071,348,22477,0.0154824932152867,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.95,16.07,11327,0,11357,0,10744,348,11120,0.031294964028777,"low bq","NA"]
["UPN_Tr2_098",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19113,321,19526,0.016439618969579,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,16.23,9828,1,9875,0.00010126582278481,9285,320,9651,0.0331571857838566,"low bq","NA"]
["UPN_Tr2_099",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",9228,157,9424,0.0166595925297114,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.79,16.04,4751,1,4773,0.000209511837418814,4477,156,4651,0.0335411739410879,"low bq","NA"]
["UPN_Tr2_100",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",15751,229,16054,0.0142643577924505,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.05,16.43,8084,3,8125,0.000369230769230769,7667,226,7929,0.0285029638037584,"low bq","NA"]
["UPN_Tr2_101",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",20729,355,21195,0.0167492333097429,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.78,16.77,10642,4,10705,0.000373657169546941,10087,351,10490,0.0334604385128694,"low bq","NA"]
["UPN_Tr2_102",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19722,362,20201,0.0179199049552002,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.81,16.69,10161,6,10228,0.000586624951114587,9561,356,9973,0.0356963802266119,"low bq","NA"]
["UPN_Tr2_103",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",16873,318,17256,0.0184283727399166,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.71,15.97,8684,1,8717,0.000114718366410462,8189,317,8539,0.0371237849865324,"low bq","NA"]
["UPN_Tr2_104",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19944,325,20358,0.0159642401021711,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.8,16.49,10240,0,10286,0,9704,325,10072,0.0322676727561557,"low bq","NA"]
["UPN_Tr2_105",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",19167,302,19523,0.0154689340777544,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.85,16.47,9835,3,9864,0.000304136253041363,9332,299,9659,0.0309555854643338,"low bq","NA"]
["UPN_Tr2_106",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",23509,380,23989,0.0158405936054025,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.91,16.22,12070,3,12128,0.000247361477572559,11439,377,11861,0.0317848410757946,"low bq","NA"]
["UPN_Tr2_107",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",29497,523,30129,0.0173586909621959,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.85,16.21,15169,6,15233,0.00039388170419484,14328,517,14896,0.0347073039742213,"low bq","NA"]
["UPN_Tr2_108",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",24154,400,24648,0.0162284972411555,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,16.28,12411,4,12465,0.000320898515844364,11743,396,12183,0.0325043092834277,"low bq","NA"]
["UPN_Tr2_109",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",24591,463,25176,0.0183905306641246,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,16.62,12648,5,12719,0.000393112666090101,11943,458,12457,0.0367664766797784,"low bq","NA"]
["UPN_Tr2_110",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",24141,396,24657,0.0160603479742061,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.9,16.65,12393,6,12460,0.000481540930979133,11748,390,12197,0.0319750758383209,"low bq","NA"]
["UPN_Tr2_111",2,25458636,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln846Pro/c.2537A>C",22402,438,22929,0.0191024466832396,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.84,16.28,11545,7,11598,0.00060355233660976,10857,431,11331,0.0380372429617862,"low bq","NA"]
["UPN_Tr2_059",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4182,63,4258,0.0147956787224049,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.53,15.44,4182,63,4258,0.0147956787224049,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_060",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4742,70,4824,0.0145107794361526,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.62,14.51,4742,70,4824,0.0145107794361526,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_061",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4543,77,4640,0.0165948275862069,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.4,15.1,4543,77,4640,0.0165948275862069,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_062",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5147,94,5262,0.0178639300646142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.12,14.8,5147,94,5262,0.0178639300646142,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_063",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5924,86,6039,0.014240768339129,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.35,14.66,5924,86,6039,0.014240768339129,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_064",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5719,86,5831,0.0147487566455153,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.45,15.52,5719,86,5831,0.0147487566455153,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_065",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3625,61,3703,0.01647312989468,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.34,15.25,3622,61,3700,0.0164864864864865,3,0,3,0,"low bq","NA"]
["UPN_Tr2_066",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3005,43,3057,0.0140660778541053,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.5,15.33,3005,43,3057,0.0140660778541053,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_067",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3340,51,3405,0.0149779735682819,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.74,14.27,3340,51,3405,0.0149779735682819,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_068",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3536,56,3610,0.0155124653739612,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.08,15.21,3536,56,3610,0.0155124653739612,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_069",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4478,78,4571,0.0170640997593524,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.45,15.88,4478,78,4571,0.0170640997593524,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_070",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3309,59,3380,0.0174556213017751,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.08,14.73,3309,59,3380,0.0174556213017751,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_071",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5740,99,5871,0.0168625447112928,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.24,14.77,5740,99,5871,0.0168625447112928,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_072",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",6410,108,6539,0.0165162868940205,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.45,14.97,6410,108,6539,0.0165162868940205,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_073",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3912,55,3983,0.0138086869194075,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.03,14.65,3912,55,3983,0.0138086869194075,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_074",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",2342,36,2383,0.0151070079731431,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.55,15.14,2342,36,2383,0.0151070079731431,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_075",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",6775,79,6876,0.0114892379290285,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.85,16.53,6775,79,6876,0.0114892379290285,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_076",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4371,75,4461,0.0168123739071957,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.04,15.23,4371,75,4461,0.0168123739071957,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_077",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4443,55,4510,0.0121951219512195,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.17,14.64,4443,55,4510,0.0121951219512195,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_078",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5983,111,6123,0.0181283684468398,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.13,15.24,5983,111,6123,0.0181283684468398,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_079",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3426,62,3505,0.0176890156918688,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.47,14.74,3426,62,3505,0.0176890156918688,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_080",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5930,94,6050,0.0155371900826446,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.36,15.06,5930,94,6050,0.0155371900826446,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_081",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",8903,135,9057,0.0149055978800927,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.35,15.19,8903,135,9057,0.0149055978800927,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_082",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",4180,74,4272,0.0173220973782772,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.56,16.55,4180,74,4272,0.0173220973782772,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_083",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5932,99,6051,0.0163609320773426,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.15,15.29,5932,99,6051,0.0163609320773426,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_084",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5314,103,5440,0.0189338235294118,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.27,15.33,5314,103,5440,0.0189338235294118,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_085",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3116,52,3183,0.0163367891925856,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.27,16.5,3116,52,3183,0.0163367891925856,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_086",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",2285,41,2340,0.0175213675213675,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.29,14.17,2276,41,2331,0.0175890175890176,9,0,9,0,"low bq","NA"]
["UPN_Tr2_087",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",5311,93,5431,0.0171239182471,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.21,15.3,5307,93,5427,0.0171365395245992,4,0,4,0,"low bq","NA"]
["UPN_Tr2_088",2,25459829,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys818Trp/c.2454T>G",3865,58,3938,0.0147282884713052,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.78,14.93,3865,58,3938,0.0147282884713052,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_062",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",5174,59,5260,0.0112167300380228,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.52,15.24,5174,59,5260,0.0112167300380228,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_065",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",3648,38,3696,0.0102813852813853,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.02,14.95,3648,38,3696,0.0102813852813853,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_066",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",3002,36,3057,0.0117762512266928,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.83,15.06,3002,36,3057,0.0117762512266928,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_067",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",3354,44,3405,0.0129221732745962,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30,14.95,3354,44,3405,0.0129221732745962,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_068",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",3553,42,3608,0.0116407982261641,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.57,14.9,3553,42,3608,0.0116407982261641,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_070",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",3317,50,3376,0.0148104265402844,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.43,14.86,3317,50,3376,0.0148104265402844,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_071",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",5791,60,5869,0.0102232066791617,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.65,14.98,5791,60,5869,0.0102232066791617,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_072",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",6439,76,6539,0.0116225722587552,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.92,15.26,6439,76,6539,0.0116225722587552,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_077",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",4444,49,4508,0.0108695652173913,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.62,14.82,4444,49,4508,0.0108695652173913,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_078",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",6028,78,6120,0.0127450980392157,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.54,14.92,6028,78,6120,0.0127450980392157,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_080",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",5970,61,6049,0.0100843114564391,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.74,15.02,5970,61,6049,0.0100843114564391,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_084",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",5342,69,5438,0.0126884884148584,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.53,15.64,5342,69,5438,0.0126884884148584,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_087",2,25459870,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttg/Gtg|p.Leu805Val/c.2413T>G",5337,69,5422,0.0127259313906308,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.68,15.03,5337,69,5422,0.0127259313906308,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_072",2,25462026,"A","C","DNMT3A","ENST00000264709","missense_variant","tTc/tGc|p.Phe794Cys/c.2381T>G",2370,32,2407,0.0132945575405069,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.49,15,2370,32,2407,0.0132945575405069,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_064",2,25462045,"C","G","DNMT3A","ENST00000264709","missense_variant","Gca/Cca|p.Ala788Pro/c.2362G>C",2440,28,2471,0.0113314447592068,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30,15.04,1253,1,1255,0.000796812749003984,1187,27,1216,0.0222039473684211,"low bq","NA"]
["UPN_Tr2_002",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",9312,115,9476,0.0121359223300971,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.96,14.95,4650,110,4779,0.023017367650136,4662,5,4697,0.00106450926123057,"low bq","NA"]
["UPN_Tr2_041",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3579,53,3662,0.0144729655925724,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.16,16.6,1797,45,1855,0.0242587601078167,1782,8,1807,0.00442722744881018,"low bq","NA"]
["UPN_Tr2_004",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1671,23,1706,0.0134818288393904,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.83,14.3,833,21,859,0.0244470314318976,838,2,847,0.00236127508854782,"low bq","NA"]
["UPN_Tr2_089",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",8224,96,8359,0.0114846273477689,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.71,15.29,4100,90,4208,0.0213878326996198,4124,6,4151,0.00144543483497952,"low bq","NA"]
["UPN_Tr2_042",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",26033,305,26535,0.0114942528735632,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.18,14.69,13084,287,13449,0.0213398765707488,12949,18,13086,0.00137551581843191,"low bq","NA"]
["UPN_Tr2_043",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",16604,233,16989,0.0137147566072164,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.19,15.07,8336,218,8610,0.0253193960511034,8268,15,8379,0.00179018976011457,"low bq","NA"]
["UPN_Tr2_044",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4552,74,4687,0.0157883507574141,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.07,15.2,2277,69,2375,0.0290526315789474,2275,5,2312,0.00216262975778547,"low bq","NA"]
["UPN_Tr2_045",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",23804,295,24371,0.0121045504903369,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.94,14.67,11971,281,12364,0.0227272727272727,11833,14,12007,0.00116598650787041,"low bq","NA"]
["UPN_Tr2_046",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",19227,258,19648,0.0131311074918567,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.93,15.15,9634,244,9939,0.0245497534963276,9593,14,9709,0.00144196106705119,"low bq","NA"]
["UPN_Tr2_047",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",27003,348,27581,0.0126173815307639,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.17,15.25,13570,327,13984,0.0233838672768879,13433,21,13597,0.00154445833639773,"low bq","NA"]
["UPN_Tr2_048",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",10695,125,10920,0.0114468864468864,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.97,14.29,5371,122,5534,0.0220455366823274,5324,3,5386,0.000556999628666914,"low bq","NA"]
["UPN_Tr2_006",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4112,47,4183,0.0112359550561798,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.21,15.3,2048,45,2103,0.021398002853067,2064,2,2080,0.000961538461538462,"low bq","NA"]
["UPN_Tr2_049",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",16207,190,16544,0.0114845261121857,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.11,14.59,8130,185,8377,0.0220842783812821,8077,5,8167,0.000612219909391453,"low bq","NA"]
["UPN_Tr2_050",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",19689,222,20093,0.0110486238988703,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.25,16,9906,204,10178,0.0200432304971507,9783,18,9915,0.00181543116490166,"low bq","NA"]
["UPN_Tr2_051",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",17442,213,17777,0.0119817742026214,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.2,15.11,8752,194,8995,0.0215675375208449,8690,19,8782,0.00216351628330676,"low bq","NA"]
["UPN_Tr2_052",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",17044,208,17392,0.0119595216191352,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.95,14.38,8551,198,8806,0.0224846695434931,8493,10,8586,0.00116468669927789,"low bq","NA"]
["UPN_Tr2_053",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",22203,280,22663,0.0123549397696686,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.04,14.51,11118,273,11464,0.0238136775994417,11085,7,11199,0.000625055808554335,"low bq","NA"]
["UPN_Tr2_054",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",12421,143,12705,0.0112554112554113,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.9,14.73,6230,137,6428,0.0213130056004978,6191,6,6277,0.00095587063884021,"low bq","NA"]
["UPN_Tr2_008",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",32066,411,32676,0.0125780389276533,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27,14.98,16008,381,16482,0.0231161266836549,16058,30,16194,0.00185253797702853,"low bq","NA"]
["UPN_Tr2_009",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",25422,293,25931,0.0112992171532143,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.21,14.39,12707,289,13085,0.0220863584256783,12715,4,12846,0.000311380974622451,"low bq","NA"]
["UPN_Tr2_010",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",13731,158,13983,0.0112994350282486,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.95,15.24,6862,149,7047,0.0211437491130978,6869,9,6936,0.00129757785467128,"low bq","NA"]
["UPN_Tr2_011",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",16272,179,16525,0.0108320726172466,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.18,16.17,8136,169,8332,0.0202832453192511,8136,10,8193,0.00122055413157574,"low bq","NA"]
["UPN_Tr2_055",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",25305,279,25824,0.0108039033457249,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.1,14.9,12713,267,13071,0.0204268992425981,12592,12,12753,0.000940955069395436,"low bq","NA"]
["UPN_Tr2_056",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",7394,80,7545,0.0106030483764082,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.98,14.4,3718,77,3821,0.0201517927244177,3676,3,3724,0.000805585392051557,"low bq","NA"]
["UPN_Tr2_090",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",6833,80,6933,0.0115390162988605,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.18,15.73,3403,75,3487,0.0215084599942644,3430,5,3446,0.00145095763203714,"low bq","NA"]
["UPN_Tr2_057",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",13981,181,14319,0.0126405475242685,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.13,15.62,7021,164,7246,0.0226331769252001,6960,17,7073,0.00240350629153117,"low bq","NA"]
["UPN_Tr2_058",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",11577,135,11810,0.0114309906858594,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.35,14.86,5825,129,5993,0.0215251126314033,5752,6,5817,0.00103145951521403,"low bq","NA"]
["UPN_Tr2_059",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2054,137,2200,0.0622727272727273,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.53,15.85,973,135,1113,0.121293800539084,1081,2,1087,0.00183992640294388,"low bq","NA"]
["UPN_Tr2_012",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",10575,110,10764,0.0102192493496841,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.18,14.29,5297,106,5437,0.0194960456133897,5278,4,5327,0.000750891683874601,"low bq","NA"]
["UPN_Tr2_060",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2810,142,2973,0.0477632021527077,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.77,15.46,1351,139,1499,0.0927284856571047,1459,3,1474,0.00203527815468114,"low bq","NA"]
["UPN_Tr2_091",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",6838,101,6973,0.0144844399827908,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.09,14.68,3396,96,3507,0.0273738237810094,3442,5,3466,0.00144258511252164,"low bq","NA"]
["UPN_Tr2_092",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3202,42,3254,0.0129071911493546,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.33,14.64,1593,41,1638,0.025030525030525,1609,1,1616,0.000618811881188119,"low bq","NA"]
["UPN_Tr2_093",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4011,48,4081,0.0117618230825778,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.3,15.12,1993,47,2048,0.02294921875,2018,1,2033,0.000491883915395967,"low bq","NA"]
["UPN_Tr2_061",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4118,252,4391,0.0573901161466636,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.62,15.68,1961,249,2220,0.112162162162162,2157,3,2171,0.00138185168125288,"low bq","NA"]
["UPN_Tr2_062",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3563,193,3781,0.0510446971700608,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.2,16.46,1714,185,1909,0.0969093766369827,1849,8,1872,0.00427350427350427,"low bq","NA"]
["UPN_Tr2_063",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3167,196,3387,0.0578683200472394,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.7,14.87,1512,193,1713,0.11266783420899,1655,3,1674,0.0017921146953405,"low bq","NA"]
["UPN_Tr2_064",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2339,130,2480,0.0524193548387097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.61,14.68,1121,130,1254,0.103668261562998,1218,0,1226,0,"low bq","NA"]
["UPN_Tr2_065",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2161,127,2312,0.0549307958477509,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.74,15.35,1038,123,1170,0.105128205128205,1123,4,1142,0.00350262697022767,"low bq","NA"]
["UPN_Tr2_066",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",821,44,874,0.0503432494279176,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.18,15.8,396,43,443,0.0970654627539503,425,1,431,0.00232018561484919,"low bq","NA"]
["UPN_Tr2_067",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",953,57,1014,0.0562130177514793,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.74,15.21,458,56,516,0.108527131782946,495,1,498,0.00200803212851406,"low bq","NA"]
["UPN_Tr2_068",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1624,109,1741,0.0626076967260195,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.51,14.78,763,109,876,0.124429223744292,861,0,865,0,"low bq","NA"]
["UPN_Tr2_069",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2665,200,2886,0.0693000693000693,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.48,15.44,1255,197,1461,0.134839151266256,1410,3,1425,0.00210526315789474,"low bq","NA"]
["UPN_Tr2_070",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1770,121,1912,0.0632845188284519,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.64,15.85,840,118,967,0.122026887280248,930,3,945,0.00317460317460317,"low bq","NA"]
["UPN_Tr2_071",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4456,252,4735,0.053220696937698,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.48,15.71,2143,248,2403,0.103204327923429,2313,4,2332,0.00171526586620926,"low bq","NA"]
["UPN_Tr2_072",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4453,271,4746,0.0571007163927518,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.64,15.46,2125,267,2400,0.11125,2328,4,2346,0.00170502983802217,"low bq","NA"]
["UPN_Tr2_073",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2671,145,2839,0.0510743219443466,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.64,15.32,1288,144,1442,0.0998613037447989,1383,1,1397,0.000715819613457409,"low bq","NA"]
["UPN_Tr2_074",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1184,76,1267,0.0599842146803473,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.93,15.74,556,76,636,0.119496855345912,628,0,631,0,"low bq","NA"]
["UPN_Tr2_075",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4154,222,4405,0.0503972758229285,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.93,16.54,2005,211,2228,0.0947037701974865,2149,11,2177,0.00505282498851631,"low bq","NA"]
["UPN_Tr2_076",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2368,147,2538,0.057919621749409,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.18,15.96,1126,144,1279,0.112587959343237,1242,3,1259,0.00238284352660842,"low bq","NA"]
["UPN_Tr2_077",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2457,137,2613,0.0524301569077688,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.17,15.77,1175,134,1317,0.101746393318147,1282,3,1296,0.00231481481481481,"low bq","NA"]
["UPN_Tr2_078",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3032,173,3216,0.0537935323383085,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.34,15.24,1451,168,1623,0.103512014787431,1581,5,1593,0.00313873195229127,"low bq","NA"]
["UPN_Tr2_079",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2137,106,2259,0.0469234174413457,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.37,16.31,1030,105,1143,0.0918635170603675,1107,1,1116,0.000896057347670251,"low bq","NA"]
["UPN_Tr2_080",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3933,215,4180,0.0514354066985646,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.44,15.4,1878,212,2105,0.100712589073634,2055,3,2075,0.00144578313253012,"low bq","NA"]
["UPN_Tr2_081",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",6408,342,6777,0.050464807436919,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.69,15.49,3080,336,3427,0.0980449372629122,3328,6,3350,0.0017910447761194,"low bq","NA"]
["UPN_Tr2_082",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2151,96,2271,0.0422721268163804,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.73,15.74,1045,91,1146,0.0794066317626527,1106,5,1125,0.00444444444444444,"low bq","NA"]
["UPN_Tr2_083",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",3675,219,3921,0.0558530986993114,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.53,16.15,1750,216,1978,0.109201213346815,1925,3,1943,0.00154400411734431,"low bq","NA"]
["UPN_Tr2_084",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2880,205,3099,0.0661503710874476,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.43,15.37,1363,202,1569,0.12874442319949,1517,3,1530,0.00196078431372549,"low bq","NA"]
["UPN_Tr2_085",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1803,108,1921,0.0562207183758459,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.44,15.52,859,106,968,0.109504132231405,944,2,953,0.00209863588667366,"low bq","NA"]
["UPN_Tr2_086",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",799,49,854,0.0573770491803279,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.14,15.51,383,49,435,0.11264367816092,416,0,419,0,"low bq","NA"]
["UPN_Tr2_087",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",2245,136,2396,0.0567612687813022,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.45,15.4,1067,136,1210,0.112396694214876,1178,0,1186,0,"low bq","NA"]
["UPN_Tr2_088",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",1906,108,2030,0.0532019704433498,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.25,15.42,909,108,1024,0.10546875,997,0,1006,0,"low bq","NA"]
["UPN_Tr2_094",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",10476,149,10667,0.0139683134902034,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.03,15.05,5209,141,5367,0.0262716601453326,5267,8,5300,0.00150943396226415,"low bq","NA"]
["UPN_Tr2_095",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",9572,131,9736,0.013455217748562,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.78,15.34,4765,126,4903,0.0256985519069957,4807,5,4833,0.00103455410717981,"low bq","NA"]
["UPN_Tr2_096",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",10833,154,11036,0.0139543312794491,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.01,15.05,5381,150,5552,0.0270172910662824,5452,4,5484,0.000729394602479942,"low bq","NA"]
["UPN_Tr2_097",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",12599,172,12821,0.013415490211372,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.16,14.79,6253,164,6437,0.0254777070063694,6346,8,6384,0.0012531328320802,"low bq","NA"]
["UPN_Tr2_098",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",7643,114,7792,0.0146303901437372,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.28,14.54,3791,109,3913,0.0278558650651674,3852,5,3879,0.00128899200824955,"low bq","NA"]
["UPN_Tr2_099",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",4828,65,4921,0.0132086974192237,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.04,14.2,2399,63,2475,0.0254545454545455,2429,2,2446,0.000817661488143908,"low bq","NA"]
["UPN_Tr2_100",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",8482,99,8623,0.0114809231126058,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.14,14.55,4220,94,4332,0.0216989843028624,4262,5,4291,0.00116522955022139,"low bq","NA"]
["UPN_Tr2_101",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",7681,105,7811,0.0134425809755473,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.78,14.81,3819,99,3928,0.02520366598778,3862,6,3883,0.00154519701261911,"low bq","NA"]
["UPN_Tr2_103",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",8544,97,8686,0.0111673958093484,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.76,14.48,4255,96,4369,0.0219729915312428,4289,1,4317,0.000231642344220524,"low bq","NA"]
["UPN_Tr2_104",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",10085,138,10264,0.0134450506625097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.91,14.25,5004,134,5155,0.0259941804073715,5081,4,5109,0.000782932080642004,"low bq","NA"]
["UPN_Tr2_105",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",8415,100,8540,0.0117096018735363,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.96,14.71,4181,98,4290,0.0228438228438228,4234,2,4250,0.000470588235294118,"low bq","NA"]
["UPN_Tr2_106",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",11923,156,12141,0.0128490239683716,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.16,14.73,5930,150,6108,0.0245579567779961,5993,6,6033,0.000994530084535057,"low bq","NA"]
["UPN_Tr2_107",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",13882,157,14109,0.0111276490183571,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.1,15.07,6902,153,7087,0.021588824608438,6980,4,7022,0.000569638279692395,"low bq","NA"]
["UPN_Tr2_108",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",12984,192,13219,0.0145245479990922,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.37,15.67,6454,175,6645,0.0263355906696764,6530,17,6574,0.00258594463036203,"low bq","NA"]
["UPN_Tr2_109",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",11578,176,11822,0.0148874978852986,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.72,14.34,5751,167,5949,0.0280719448646831,5827,9,5873,0.0015324365741529,"low bq","NA"]
["UPN_Tr2_110",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",12990,190,13215,0.0143776012107454,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.95,15.09,6457,177,6648,0.0266245487364621,6533,13,6567,0.00197959494441906,"low bq","NA"]
["UPN_Tr2_111",2,25462051,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser786Ala/c.2356T>G",9455,138,9636,0.014321295143213,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.79,14.51,4687,135,4839,0.027898326100434,4768,3,4797,0.000625390869293308,"low bq","NA"]
["UPN_Tr2_059",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2120,51,2200,0.0231818181818182,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.44,14.9,1050,49,1112,0.0440647482014388,1070,2,1088,0.00183823529411765,"low bq","NA"]
["UPN_Tr2_060",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2900,53,2975,0.0178151260504202,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.99,15.7,1446,48,1499,0.0320213475650434,1454,5,1476,0.00338753387533875,"low bq","NA"]
["UPN_Tr2_061",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",4269,93,4394,0.0211652253072371,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.49,15.7,2118,92,2220,0.0414414414414414,2151,1,2174,0.000459981600735971,"low bq","NA"]
["UPN_Tr2_062",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",3652,93,3783,0.0245836637589215,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.36,14.85,1803,93,1909,0.0487166055526454,1849,0,1874,0,"low bq","NA"]
["UPN_Tr2_063",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",3274,87,3388,0.0256788665879575,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.86,15.16,1625,84,1713,0.0490367775831874,1649,3,1675,0.0017910447761194,"low bq","NA"]
["UPN_Tr2_064",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2385,66,2474,0.026677445432498,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.59,14.91,1175,65,1247,0.0521251002405774,1210,1,1227,0.000814995925020375,"low bq","NA"]
["UPN_Tr2_065",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2211,64,2314,0.0276577355229041,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.71,14.11,1093,61,1170,0.0521367521367521,1118,3,1144,0.00262237762237762,"low bq","NA"]
["UPN_Tr2_066",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",839,25,876,0.0285388127853881,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.59,14.28,415,23,443,0.0519187358916479,424,2,433,0.0046189376443418,"low bq","NA"]
["UPN_Tr2_068",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",1695,32,1741,0.0183802412406663,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.18,14,842,30,876,0.0342465753424658,853,2,865,0.0023121387283237,"low bq","NA"]
["UPN_Tr2_069",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2792,66,2887,0.0228611014894354,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.22,14.74,1387,64,1461,0.0438056125941136,1405,2,1426,0.00140252454417952,"low bq","NA"]
["UPN_Tr2_070",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",1837,59,1912,0.0308577405857741,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.31,15.63,907,54,967,0.0558428128231644,930,5,945,0.00529100529100529,"low bq","NA"]
["UPN_Tr2_071",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",4561,115,4736,0.0242820945945946,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.46,15.43,2269,113,2403,0.0470245526425302,2292,2,2333,0.00085726532361766,"low bq","NA"]
["UPN_Tr2_072",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",4579,110,4745,0.0231822971548999,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.54,14.62,2270,105,2398,0.0437864887406172,2309,5,2347,0.00213037920749893,"low bq","NA"]
["UPN_Tr2_073",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2760,56,2839,0.0197252553716097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.63,14.32,1380,54,1439,0.0375260597637248,1380,2,1400,0.00142857142857143,"low bq","NA"]
["UPN_Tr2_074",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",1224,33,1267,0.0260457774269929,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.63,15.61,602,32,636,0.050314465408805,622,1,631,0.00158478605388273,"low bq","NA"]
["UPN_Tr2_075",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",4270,99,4406,0.0224693599636859,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.95,14.45,2124,93,2228,0.0417414721723519,2146,6,2178,0.00275482093663912,"low bq","NA"]
["UPN_Tr2_076",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2462,52,2537,0.0204966495861253,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.98,14.13,1221,52,1278,0.0406885758998435,1241,0,1259,0,"low bq","NA"]
["UPN_Tr2_077",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2530,55,2615,0.0210325047801147,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.01,14.56,1254,52,1317,0.0394836750189825,1276,3,1298,0.00231124807395994,"low bq","NA"]
["UPN_Tr2_078",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",3102,88,3218,0.0273461777501554,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.23,14.47,1530,83,1623,0.0511398644485521,1572,5,1595,0.00313479623824451,"low bq","NA"]
["UPN_Tr2_079",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2192,51,2260,0.0225663716814159,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.46,14.8,1091,47,1143,0.0411198600174978,1101,4,1117,0.0035810205908684,"low bq","NA"]
["UPN_Tr2_080",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",4068,83,4182,0.0198469631755141,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.57,14.55,2016,78,2105,0.0370546318289786,2052,5,2077,0.00240731824747232,"low bq","NA"]
["UPN_Tr2_081",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",6576,137,6778,0.0202124520507524,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.66,14.77,3276,130,3426,0.0379451255107998,3300,7,3352,0.00208830548926014,"low bq","NA"]
["UPN_Tr2_082",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2201,53,2272,0.0233274647887324,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.73,15.91,1092,47,1146,0.0410122164048866,1109,6,1126,0.00532859680284192,"low bq","NA"]
["UPN_Tr2_083",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",3797,87,3923,0.0221769054295182,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.39,14.15,1880,85,1978,0.0429726996966633,1917,2,1945,0.00102827763496144,"low bq","NA"]
["UPN_Tr2_084",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2974,78,3100,0.0251612903225806,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.46,14.91,1474,75,1568,0.0478316326530612,1500,3,1532,0.00195822454308094,"low bq","NA"]
["UPN_Tr2_085",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",1864,42,1922,0.0218522372528616,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.24,14.81,926,39,968,0.0402892561983471,938,3,954,0.00314465408805031,"low bq","NA"]
["UPN_Tr2_087",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",2322,47,2396,0.0196160267111853,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.37,14.53,1157,46,1210,0.0380165289256198,1165,1,1186,0.000843170320404722,"low bq","NA"]
["UPN_Tr2_088",2,25462053,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val785Gly/c.2354T>G",1959,47,2032,0.0231299212598425,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.09,15.19,969,47,1024,0.0458984375,990,0,1008,0,"low bq","NA"]
["UPN_Tr2_053",2,25462053,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val785Glu/c.2354T>A",22241,227,22647,0.0100234026581887,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.79,19.38,11269,45,11436,0.00393494228751312,10972,182,11211,0.0162340558380162,"low bq","NA"]
["UPN_Tr2_057",2,25462053,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val785Glu/c.2354T>A",14083,151,14324,0.0105417481150517,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.02,20.76,7134,39,7239,0.00538748445917945,6949,112,7085,0.0158080451658433,"low bq","NA"]
["UPN_Tr2_059",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",2165,29,2206,0.0131459655485041,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.03,14.24,1080,24,1112,0.0215827338129496,1085,5,1094,0.00457038391224863,"low bq","NA"]
["UPN_Tr2_060",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",2931,38,2979,0.0127559583752937,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.91,14,1455,38,1499,0.0253502334889927,1476,0,1480,0,"low bq","NA"]
["UPN_Tr2_061",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",4303,58,4399,0.0131848147306206,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.68,14.69,2147,52,2219,0.0234339792699414,2156,6,2180,0.00275229357798165,"low bq","NA"]
["UPN_Tr2_062",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",3703,60,3793,0.0158186132349064,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.66,14.52,1833,57,1909,0.0298585646935568,1870,3,1884,0.00159235668789809,"low bq","NA"]
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["UPN_Tr2_064",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",2433,26,2476,0.0105008077544426,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.99,14.27,1212,25,1247,0.0200481154771451,1221,1,1229,0.00081366965012205,"low bq","NA"]
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["UPN_Tr2_087",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",2340,30,2399,0.0125052105043768,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.64,14,1163,27,1209,0.0223325062034739,1177,3,1190,0.00252100840336134,"low bq","NA"]
["UPN_Tr2_088",2,25462055,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu784Asp/c.2352A>C",1996,22,2033,0.0108214461387113,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.99,14.82,995,22,1024,0.021484375,1001,0,1009,0,"low bq","NA"]
["UPN_Tr2_060",2,25462056,"T","G","DNMT3A","ENST00000264709","missense_variant","gAa/gCa|p.Glu784Ala/c.2351A>C",2933,35,2979,0.0117489090298758,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.43,14.77,1478,14,1499,0.00933955970647098,1455,21,1480,0.0141891891891892,"low bq","NA"]
["UPN_Tr2_069",2,25462056,"T","G","DNMT3A","ENST00000264709","missense_variant","gAa/gCa|p.Glu784Ala/c.2351A>C",2839,33,2889,0.0114226375908619,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.2,14,1428,20,1459,0.0137080191912269,1411,13,1430,0.00909090909090909,"low bq","NA"]
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["UPN_Tr2_083",2,25462056,"T","G","DNMT3A","ENST00000264709","missense_variant","gAa/gCa|p.Glu784Ala/c.2351A>C",3869,46,3925,0.0117197452229299,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.13,15.11,1953,19,1978,0.0096056622851365,1916,27,1947,0.0138674884437596,"low bq","NA"]
["UPN_Tr2_084",2,25462056,"T","G","DNMT3A","ENST00000264709","missense_variant","gAa/gCa|p.Glu784Ala/c.2351A>C",3055,35,3102,0.0112830431979368,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.91,14,1541,18,1568,0.0114795918367347,1514,17,1534,0.0110821382007823,"low bq","NA"]
["UPN_Tr2_061",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",4329,47,4400,0.0106818181818182,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.94,14.15,2160,46,2219,0.0207300585849482,2169,1,2181,0.000458505272810637,"low bq","NA"]
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["UPN_Tr2_070",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",1868,26,1914,0.0135841170323929,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.57,15,932,25,966,0.025879917184265,936,1,948,0.00105485232067511,"low bq","NA"]
["UPN_Tr2_080",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",4116,49,4183,0.0117140808032513,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.8,14.27,2053,43,2105,0.0204275534441805,2063,6,2078,0.00288739172281039,"low bq","NA"]
["UPN_Tr2_081",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",6661,73,6789,0.010752688172043,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.91,14.85,3331,66,3425,0.0192700729927007,3330,7,3364,0.00208085612366231,"low bq","NA"]
["UPN_Tr2_082",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",2235,25,2276,0.0109841827768014,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.81,16.68,1114,22,1146,0.0191972076788831,1121,3,1130,0.00265486725663717,"low bq","NA"]
["UPN_Tr2_083",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",3864,41,3924,0.0104485219164118,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.78,14.17,1930,38,1977,0.0192210419828022,1934,3,1947,0.00154083204930663,"low bq","NA"]
["UPN_Tr2_084",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",3047,38,3102,0.0122501611863314,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.63,14.92,1520,38,1568,0.024234693877551,1527,0,1534,0,"low bq","NA"]
["UPN_Tr2_085",2,25462058,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys783Asn/c.2349A>C",1884,22,1923,0.0114404576183047,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.69,16.59,938,20,968,0.0206611570247934,946,2,955,0.00209424083769634,"low bq","NA"]
["UPN_Tr2_077",2,25462059,"T","G","DNMT3A","ENST00000264709","missense_variant","aAa/aCa|p.Lys783Thr/c.2348A>C",2577,29,2618,0.0110771581359817,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.43,14,1284,27,1317,0.020501138952164,1293,2,1301,0.00153727901614143,"low bq","NA"]
["UPN_Tr2_062",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",3719,48,3793,0.0126548905879251,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.94,16.21,1856,43,1908,0.0225366876310273,1863,5,1885,0.0026525198938992,"low bq","NA"]
["UPN_Tr2_063",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",3335,35,3393,0.0103153551429413,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.21,16.66,1672,31,1713,0.018096906012843,1663,4,1680,0.00238095238095238,"low bq","NA"]
["UPN_Tr2_068",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",1708,23,1742,0.013203214695752,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.62,14,850,20,876,0.0228310502283105,858,3,866,0.00346420323325635,"low bq","NA"]
["UPN_Tr2_069",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2826,42,2891,0.0145278450363196,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.03,14.74,1409,40,1459,0.0274160383824537,1417,2,1432,0.00139664804469274,"low bq","NA"]
["UPN_Tr2_070",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",1878,20,1913,0.0104547830632514,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.49,15.3,940,18,965,0.0186528497409326,938,2,948,0.00210970464135021,"low bq","NA"]
["UPN_Tr2_072",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",4665,56,4752,0.0117845117845118,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,14.23,2333,52,2397,0.0216937838965373,2332,4,2355,0.00169851380042463,"low bq","NA"]
["UPN_Tr2_073",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2803,31,2849,0.0108810108810109,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.29,14,1405,28,1439,0.019457956914524,1398,3,1410,0.00212765957446809,"low bq","NA"]
["UPN_Tr2_076",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2494,29,2544,0.0113993710691824,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.71,14.45,1240,27,1278,0.0211267605633803,1254,2,1266,0.00157977883096367,"low bq","NA"]
["UPN_Tr2_078",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",3159,40,3222,0.0124146492861577,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.82,15.32,1576,35,1621,0.0215916101172116,1583,5,1601,0.00312304809494066,"low bq","NA"]
["UPN_Tr2_079",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2202,28,2261,0.0123839009287926,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.23,14.64,1097,26,1141,0.0227870289219982,1105,2,1120,0.00178571428571429,"low bq","NA"]
["UPN_Tr2_082",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2230,27,2275,0.0118681318681319,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.09,14,1115,21,1145,0.0183406113537118,1115,6,1130,0.00530973451327434,"low bq","NA"]
["UPN_Tr2_083",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",3857,43,3924,0.0109582059123344,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,14.63,1926,39,1977,0.0197268588770865,1931,4,1947,0.00205444273240883,"low bq","NA"]
["UPN_Tr2_084",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",3052,38,3102,0.0122501611863314,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.8,15,1529,34,1568,0.0216836734693878,1523,4,1534,0.00260756192959583,"low bq","NA"]
["UPN_Tr2_085",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",1889,23,1920,0.0119791666666667,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.84,15.13,940,21,965,0.0217616580310881,949,2,955,0.00209424083769634,"low bq","NA"]
["UPN_Tr2_087",2,25462064,"A","C","DNMT3A","ENST00000264709","missense_variant","gaT/gaG|p.Asp781Glu/c.2343T>G",2368,24,2399,0.0100041684035015,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.24,14.54,1187,19,1209,0.0157154673283706,1181,5,1190,0.00420168067226891,"low bq","NA"]
["UPN_Tr2_060",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2897,39,2979,0.013091641490433,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.94,15.31,1457,21,1499,0.0140093395597065,1440,18,1480,0.0121621621621622,"low bq","NA"]
["UPN_Tr2_061",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",4327,56,4398,0.0127330604820373,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.71,14.45,2176,34,2217,0.0153360396932792,2151,22,2181,0.010087116001834,"low bq","NA"]
["UPN_Tr2_063",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",3326,43,3392,0.0126768867924528,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.9,14,1682,18,1712,0.0105140186915888,1644,25,1680,0.0148809523809524,"low bq","NA"]
["UPN_Tr2_064",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2438,30,2478,0.0121065375302663,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.68,14,1230,12,1247,0.00962309542902967,1208,18,1231,0.0146222583265638,"low bq","NA"]
["UPN_Tr2_065",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2276,36,2320,0.0155172413793103,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29,14,1149,17,1170,0.0145299145299145,1127,19,1150,0.0165217391304348,"low bq","NA"]
["UPN_Tr2_068",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",1711,27,1741,0.0155083285468122,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.41,14.48,859,14,875,0.016,852,13,866,0.0150115473441109,"low bq","NA"]
["UPN_Tr2_069",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2832,41,2892,0.0141770401106501,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.54,14.32,1430,20,1459,0.0137080191912269,1402,21,1433,0.0146545708304257,"low bq","NA"]
["UPN_Tr2_070",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",1859,35,1913,0.01829587036069,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.53,14.51,936,19,965,0.0196891191709845,923,16,948,0.0168776371308017,"low bq","NA"]
["UPN_Tr2_071",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",4640,70,4736,0.0147804054054054,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.76,14.44,2343,40,2397,0.0166875260742595,2297,30,2339,0.0128259940145361,"low bq","NA"]
["UPN_Tr2_072",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",4656,62,4751,0.0130498842348979,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.61,14.61,2342,38,2396,0.0158597662771285,2314,24,2355,0.0101910828025478,"low bq","NA"]
["UPN_Tr2_073",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2796,41,2849,0.0143910143910144,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.01,15.34,1411,21,1439,0.014593467685893,1385,20,1410,0.0141843971631206,"low bq","NA"]
["UPN_Tr2_074",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",1231,25,1267,0.0197316495659037,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.34,14,615,14,635,0.0220472440944882,616,11,632,0.0174050632911392,"low bq","NA"]
["UPN_Tr2_075",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",4344,60,4418,0.0135808057944771,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.09,14.22,2187,34,2228,0.0152603231597846,2157,26,2190,0.0118721461187215,"low bq","NA"]
["UPN_Tr2_076",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2486,43,2544,0.0169025157232704,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.49,14,1247,23,1278,0.0179968701095462,1239,20,1266,0.0157977883096366,"low bq","NA"]
["UPN_Tr2_077",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2572,31,2619,0.0118365788468881,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.43,14,1296,12,1316,0.00911854103343465,1276,19,1303,0.0145817344589409,"low bq","NA"]
["UPN_Tr2_078",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",3172,33,3221,0.0102452654455138,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.41,14.94,1599,13,1620,0.00802469135802469,1573,20,1601,0.0124921923797626,"low bq","NA"]
["UPN_Tr2_079",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2210,31,2260,0.013716814159292,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.94,14.42,1117,13,1140,0.0114035087719298,1093,18,1120,0.0160714285714286,"low bq","NA"]
["UPN_Tr2_081",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",6643,102,6783,0.0150375939849624,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.15,14.83,3351,48,3419,0.0140391927464171,3292,54,3364,0.0160523186682521,"low bq","NA"]
["UPN_Tr2_082",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2237,23,2275,0.0101098901098901,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.45,14.57,1123,14,1145,0.0122270742358079,1114,9,1130,0.0079646017699115,"low bq","NA"]
["UPN_Tr2_083",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",3861,49,3924,0.0124872579001019,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.75,15.65,1945,25,1977,0.0126454223571067,1916,24,1947,0.012326656394453,"low bq","NA"]
["UPN_Tr2_084",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",3039,45,3101,0.0145114479200258,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.3,14,1534,25,1567,0.0159540523292916,1505,20,1534,0.0130378096479791,"low bq","NA"]
["UPN_Tr2_085",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",1884,23,1920,0.0119791666666667,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.82,14.96,945,13,965,0.0134715025906736,939,10,955,0.0104712041884817,"low bq","NA"]
["UPN_Tr2_087",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2357,27,2398,0.0112593828190158,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.09,14.48,1187,13,1208,0.0107615894039735,1170,14,1190,0.0117647058823529,"low bq","NA"]
["UPN_Tr2_088",2,25462065,"T","G","DNMT3A","ENST00000264709","missense_variant","gAt/gCt|p.Asp781Ala/c.2342A>C",2000,27,2031,0.0132939438700148,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.25,15.63,1005,15,1022,0.0146771037181996,995,12,1009,0.0118929633300297,"low bq","NA"]
["UPN_Tr2_059",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",2153,35,2208,0.0158514492753623,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.45,17.26,1076,28,1110,0.0252252252252252,1077,7,1098,0.0063752276867031,"low bq","NA"]
["UPN_Tr2_060",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",2923,44,2979,0.0147700570661296,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.76,14.16,1460,34,1499,0.0226817878585724,1463,10,1480,0.00675675675675676,"low bq","NA"]
["UPN_Tr2_061",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",4295,74,4398,0.0168258299226921,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.45,15.22,2146,60,2217,0.027063599458728,2149,14,2181,0.00641907381934892,"low bq","NA"]
["UPN_Tr2_062",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",3692,75,3795,0.0197628458498024,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.97,15.17,1846,54,1907,0.0283167278447824,1846,21,1888,0.0111228813559322,"low bq","NA"]
["UPN_Tr2_063",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",3307,51,3393,0.0150309460654288,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.57,14,1652,43,1712,0.0251168224299065,1655,8,1681,0.00475907198096371,"low bq","NA"]
["UPN_Tr2_064",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",2409,49,2479,0.0197660346914078,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.7,14.14,1203,38,1247,0.0304731355252606,1206,11,1232,0.00892857142857143,"low bq","NA"]
["UPN_Tr2_072",2,25462068,"A","C","DNMT3A","ENST00000264709","missense_variant","aTt/aGt|p.Ile780Ser/c.2339T>G",4634,91,4751,0.0191538623447695,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.5,15.76,2316,74,2395,0.0308977035490605,2318,17,2356,0.00721561969439728,"low bq","NA"]
["UPN_Tr2_072",2,25462080,"T","G","DNMT3A","ENST00000264709","missense_variant","aAc/aCc|p.Asn776Thr/c.2327A>C",4553,161,4748,0.0339090143218197,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.03,14.81,2272,97,2386,0.0406538139145013,2281,64,2362,0.0270956816257409,"low bq","NA"]
["UPN_Tr2_063",2,25463217,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val759Gly/c.2276T>G",8530,127,8699,0.014599379238993,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.8,14.65,8530,127,8699,0.014599379238993,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_049",2,25463226,"T","A","DNMT3A","ENST00000264709","missense_variant","gAg/gTg|p.Glu756Val/c.2267A>T",33875,432,34457,0.0125373654119627,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.76,17.07,17443,62,17572,0.003528340541771,16432,370,16885,0.0219129404797157,"low bq","NA"]
["UPN_Tr2_077",2,25464462,"A","C","DNMT3A","ENST00000264709","missense_variant","gTc/gGc|p.Val684Gly/c.2051T>G",10583,330,10941,0.0301617768028517,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.06,15.11,10583,330,10941,0.0301617768028517,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_042",2,25464483,"T","G","DNMT3A","ENST00000264709","missense_variant","cAc/cCc|p.His677Pro/c.2030A>C",10278,129,10475,0.0123150357995227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.36,16.03,9911,3,9980,0.00030060120240481,367,126,495,0.254545454545455,"low bq","NA"]
["UPN_Tr2_086",2,25464483,"T","G","DNMT3A","ENST00000264709","missense_variant","cAc/cCc|p.His677Pro/c.2030A>C",6407,162,6609,0.0245120290512937,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.28,20.61,6255,1,6295,0.000158856235107228,152,161,314,0.512738853503185,"low bq","NA"]
["UPN_Tr2_073",2,25464498,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val672Gly/c.2015T>G",14996,411,15547,0.0264359683540233,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.75,14.64,7459,356,7859,0.0452983840183229,7537,55,7688,0.00715400624349636,"low bq","NA"]
["UPN_Tr2_074",2,25464502,"T","G","DNMT3A","ENST00000264709","missense_variant","Acg/Ccg|p.Thr671Pro/c.2011A>C",12597,167,12818,0.0130285535965049,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.85,14.98,6414,22,6468,0.00340136054421769,6183,145,6350,0.0228346456692913,"low bq","NA"]
["UPN_Tr2_074",2,25464510,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp668Ala/c.2003A>C",12586,151,12821,0.0117775524530068,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.18,14.8,6422,13,6465,0.0020108275328693,6164,138,6356,0.0217117684078037,"low bq","NA"]
["UPN_Tr2_071",2,25464517,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgt/Ggt|p.Cys666Gly/c.1996T>G",11077,177,11351,0.0155933397938508,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.63,14.79,5543,155,5740,0.0270034843205575,5534,22,5611,0.00392086972019248,"low bq","NA"]
["UPN_Tr2_072",2,25464540,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp658Ala/c.1973A>C",15470,245,15807,0.0154994622635541,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.51,14.6,7900,30,7968,0.00376506024096386,7570,215,7839,0.0274269677254752,"low bq","NA"]
["UPN_Tr2_069",2,25466791,"A","C","DNMT3A","ENST00000264709","missense_variant","Tct/Gct|p.Ser638Ala/c.1912T>G",4885,53,4949,0.010709234188725,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.73,15.04,4885,53,4949,0.010709234188725,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_066",2,25466841,"T","G","DNMT3A","ENST00000264709","missense_variant","aAg/aCg|p.Lys621Thr/c.1862A>C",4772,50,4852,0.0103050288540808,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.63,14.64,4772,50,4852,0.0103050288540808,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_007",2,25467027,"T","A","DNMT3A","ENST00000264709","missense_variant","gaA/gaT|p.Glu616Asp/c.1848A>T",10162,154,10359,0.0148662998358915,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.12,15.95,10162,154,10359,0.0148662998358915,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_044",2,25467043,"T","A","DNMT3A","ENST00000264709","missense_variant","aAt/aTt|p.Asn611Ile/c.1832A>T",2531,34,2578,0.013188518231187,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.44,16.15,2531,34,2578,0.013188518231187,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_015",2,25467058,"T","A","DNMT3A","ENST00000264709","missense_variant","cAg/cTg|p.Gln606Leu/c.1817A>T",9245,146,9415,0.0155071694105151,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.51,17.47,9245,146,9415,0.0155071694105151,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_075",2,25467058,"T","A","DNMT3A","ENST00000264709","missense_variant","cAg/cTg|p.Gln606Leu/c.1817A>T",2830,29,2870,0.0101045296167247,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.48,16.76,2830,29,2870,0.0101045296167247,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_013",2,25467076,"T","A","DNMT3A","ENST00000264709","missense_variant","gAc/gTc|p.Asp600Val/c.1799A>T",2510,28,2541,0.0110192837465565,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.64,17.18,2510,28,2541,0.0110192837465565,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_074",2,25467094,"A","C","DNMT3A","ENST00000264709","missense_variant","cTg/cGg|p.Leu594Arg/c.1781T>G",1546,25,1579,0.0158328055731476,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,14,754,25,783,0.0319284802043423,792,0,796,0,"low bq","NA"]
["UPN_Tr2_086",2,25467104,"T","G","DNMT3A","ENST00000264709","missense_variant","Acc/Ccc|p.Thr591Pro/c.1771A>C",1506,24,1536,0.015625,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.29,16.38,750,2,755,0.00264900662251656,756,22,781,0.028169014084507,"low bq","NA"]
["UPN_Tr2_045",2,25467139,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp579Ala/c.1736A>C",10940,262,11264,0.0232599431818182,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.81,14.43,0,0,0,"NA",10940,262,11264,0.0232599431818182,"low bq","NA"]
["UPN_Tr2_097",2,25467139,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp579Ala/c.1736A>C",6197,122,6335,0.019258089976322,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.97,15.1,0,0,0,"NA",6197,122,6335,0.019258089976322,"low bq","NA"]
["UPN_Tr2_087",2,25467463,"G","C","DNMT3A","ENST00000264709","missense_variant","aCc/aGc|p.Thr538Ser/c.1613C>G",3403,38,3452,0.0110081112398609,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.21,14,3403,38,3452,0.0110081112398609,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_081",2,25467475,"T","A","DNMT3A","ENST00000264709","missense_variant","cAg/cTg|p.Gln534Leu/c.1601A>T",6370,65,6456,0.0100681536555143,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.5,19.49,6352,65,6438,0.0100963031997515,18,0,18,0,"low bq","NA"]
["UPN_Tr2_083",2,25467484,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp531Ala/c.1592A>C",7382,85,7514,0.0113122171945701,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.19,14.64,3670,8,3713,0.0021545919741449,3712,77,3801,0.0202578268876611,"low bq","NA"]
["UPN_Tr2_011",2,25468196,"A","T","DNMT3A","ENST00000264709","missense_variant","Tgc/Agc|p.Cys494Ser/c.1480T>A",15065,158,15295,0.010330173259235,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.92,16.75,7723,12,7771,0.00154420280530176,7342,146,7524,0.019404572036151,"low bq","NA"]
["UPN_Tr2_058",2,25469149,"T","A","DNMT3A","ENST00000264709","missense_variant","Acg/Tcg|p.Thr437Ser/c.1309A>T",10387,148,10595,0.0139688532326569,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.41,16.78,10354,148,10558,0.0140178064027278,33,0,37,0,"low bq","NA"]
["UPN_Tr2_083",2,25469566,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val401Gly/c.1202T>G",879,44,932,0.0472103004291846,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",19.8,14,879,44,932,0.0472103004291846,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_081",2,25469589,"A","C","DNMT3A","ENST00000264709","missense_variant","agT/agG|p.Ser393Arg/c.1179T>G",5938,162,6136,0.0264015645371578,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.81,14.93,2912,161,3088,0.0521373056994819,3026,1,3048,0.000328083989501312,"low bq","NA"]
["UPN_Tr2_084",2,25469960,"T","G","DNMT3A","ENST00000264709","missense_variant","aAg/aCg|p.Lys361Thr/c.1082A>C",2781,32,2821,0.011343495214463,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.74,14,2781,32,2821,0.011343495214463,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_060",2,25469982,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttc/Gtc|p.Phe354Val/c.1060T>G",2012,124,2156,0.0575139146567718,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",16.24,14.35,2012,124,2156,0.0575139146567718,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_064",2,25469992,"A","C","DNMT3A","ENST00000264709","missense_variant","ttT/ttG|p.Phe350Leu/c.1050T>G",1973,21,2004,0.0104790419161677,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.41,14.86,1951,21,1982,0.0105953582240161,22,0,22,0,"low bq","NA"]
["UPN_Tr2_075",2,25469994,"A","C","DNMT3A","ENST00000264709","missense_variant","Ttt/Gtt|p.Phe350Val/c.1048T>G",2761,110,2894,0.0380096751900484,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",17.56,14.2,2761,110,2894,0.0380096751900484,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_077",2,25469997,"A","C","DNMT3A","ENST00000264709","missense_variant","Tcg/Gcg|p.Ser349Ala/c.1045T>G",2025,169,2203,0.076713572401271,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.65,14.55,2000,169,2178,0.0775941230486685,25,0,25,0,"low bq","NA"]
["UPN_Tr2_062",2,25470008,"A","C","DNMT3A","ENST00000264709","missense_variant","aTg/aGg|p.Met345Arg/c.1034T>G",2780,141,2938,0.0479918311776719,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",17.44,14.05,2750,141,2908,0.0484869325997249,30,0,30,0,"low bq","NA"]
["UPN_Tr2_069",2,25470011,"A","C","DNMT3A","ENST00000264709","missense_variant","cTg/cGg|p.Leu344Arg/c.1031T>G",6052,171,6253,0.0273468735007197,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",23.97,14.19,2978,148,3142,0.0471037555697008,3074,23,3111,0.00739312118289939,"low bq","NA"]
["UPN_Tr2_071",2,25470015,"T","G","DNMT3A","ENST00000264709","missense_variant","Aag/Cag|p.Lys343Gln/c.1027A>C",5020,77,5128,0.015015600624025,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.13,14.52,2526,35,2575,0.0135922330097087,2494,42,2553,0.0164512338425382,"low bq","NA"]
["UPN_Tr2_078",2,25470020,"A","C","DNMT3A","ENST00000264709","missense_variant","gTt/gGt|p.Val341Gly/c.1022T>G",5402,353,5824,0.0606112637362637,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",20.29,14.15,2557,308,2907,0.105951152390781,2845,45,2917,0.0154268083647583,"low bq","NA"]
["UPN_Tr2_065",2,25470022,"A","C","DNMT3A","ENST00000264709","missense_variant","tgT/tgG|p.Cys340Trp/c.1020T>G",1888,117,2015,0.0580645161290323,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.42,14.49,904,103,1012,0.101778656126482,984,14,1003,0.0139581256231306,"low bq","NA"]
["UPN_Tr2_028",2,25470024,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgt/Ggt|p.Cys340Gly/c.1018T>G",8117,146,8327,0.0175333253272487,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.47,14.84,4031,121,4176,0.0289750957854406,4086,25,4151,0.00602264514574801,"low bq","NA"]
["UPN_Tr2_074",2,25470024,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgt/Ggt|p.Cys340Gly/c.1018T>G",1867,176,2060,0.0854368932038835,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.47,14.34,849,159,1014,0.156804733727811,1018,17,1046,0.0162523900573614,"low bq","NA"]
["UPN_Tr2_010",2,25470026,"A","C","DNMT3A","ENST00000264709","missense_variant","gTg/gGg|p.Val339Gly/c.1016T>G",7878,122,8061,0.0151345986850267,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.33,15.41,3930,73,4028,0.0181231380337637,3948,49,4033,0.0121497644433424,"low bq","NA"]
["UPN_Tr2_055",2,25470489,"T","A","DNMT3A","ENST00000264709","missense_variant","Atg/Ttg|p.Met329Leu/c.985A>T",7761,92,7890,0.011660329531052,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.12,17.45,7759,92,7888,0.0116632860040568,2,0,2,0,"low bq","NA"]
["UPN_Tr2_064",2,25470530,"A","C","DNMT3A","ENST00000264709","missense_variant","aTg/aGg|p.Met315Arg/c.944T>G",4305,62,4393,0.014113362167084,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.8,14.11,2154,56,2220,0.0252252252252252,2151,6,2173,0.00276115968706857,"low bq","NA"]
["UPN_Tr2_054",2,25470540,"A","C","DNMT3A","ENST00000264709","missense_variant","Tct/Gct|p.Ser312Ala/c.934T>G",7809,87,7952,0.0109406438631791,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.63,14.47,3917,77,4009,0.0192067847343477,3892,10,3943,0.00253613999492772,"low bq","NA"]
["UPN_Tr2_042",2,25470546,"T","A","DNMT3A","ENST00000264709","missense_variant","Att/Ttt|p.Ile310Phe/c.928A>T",10236,212,10488,0.0202135774218154,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",30.53,16.39,5084,195,5298,0.036806342015855,5152,17,5190,0.00327552986512524,"low bq","NA"]
["UPN_Tr2_049",2,25470546,"T","A","DNMT3A","ENST00000264709","missense_variant","Att/Ttt|p.Ile310Phe/c.928A>T",6872,123,7018,0.0175263607865489,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",30.48,15.98,3413,116,3539,0.0327776207968353,3459,7,3479,0.00201207243460765,"low bq","NA"]
["UPN_Tr2_009",2,25470558,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgg/Ggg|p.Trp306Gly/c.916T>G",11844,160,12068,0.0132582035134239,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.21,14.64,5897,159,6070,0.0261943986820428,5947,1,5998,0.000166722240746916,"low bq","NA"]
["UPN_Tr2_063",2,25470566,"A","C","DNMT3A","ENST00000264709","missense_variant","tTc/tGc|p.Phe303Cys/c.908T>G",3039,111,3170,0.0350157728706625,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.32,14.77,1475,109,1592,0.0684673366834171,1564,2,1578,0.00126742712294043,"low bq","NA"]
["UPN_Tr2_017",2,25470573,"G","C","DNMT3A","ENST00000264709","missense_variant","Cgg/Ggg|p.Arg301Gly/c.901C>G",3080,36,3129,0.0115052732502397,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.75,14,1517,36,1558,0.0231065468549422,1563,0,1571,0,"low bq","NA"]
["UPN_Tr2_091",2,25470573,"G","C","DNMT3A","ENST00000264709","missense_variant","Cgg/Ggg|p.Arg301Gly/c.901C>G",4102,93,4203,0.0221270521056388,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.65,14.7,1996,91,2089,0.0435615126854955,2106,2,2114,0.000946073793755913,"low bq","NA"]
["UPN_Tr2_021",2,25470575,"A","C","DNMT3A","ENST00000264709","missense_variant","cTg/cGg|p.Leu300Arg/c.899T>G",5502,82,5627,0.0145725964101653,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.46,14.4,2682,82,2779,0.0295070169125585,2820,0,2848,0,"low bq","NA"]
["UPN_Tr2_079",2,25470575,"A","C","DNMT3A","ENST00000264709","missense_variant","cTg/cGg|p.Leu300Arg/c.899T>G",2220,43,2273,0.0189177298724153,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.46,14.65,1082,43,1129,0.0380868024800709,1138,0,1144,0,"low bq","NA"]
["UPN_Tr2_010",2,25470576,"G","C","DNMT3A","ENST00000264709","missense_variant","Ctg/Gtg|p.Leu300Val/c.898C>G",7581,87,7689,0.0113148653921186,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.73,14,3715,86,3814,0.0225485055060304,3866,1,3875,0.000258064516129032,"low bq","NA"]
["UPN_Tr2_007",2,25470577,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys299Asn/c.897A>C",10575,177,10842,0.0163254012174875,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.03,16.33,5142,158,5374,0.029400818756978,5433,19,5468,0.003474762253109,"low bq","NA"]
["UPN_Tr2_058",2,25470577,"T","G","DNMT3A","ENST00000264709","missense_variant","aaA/aaC|p.Lys299Asn/c.897A>C",7377,135,7581,0.0178076770874555,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.14,16.26,3589,123,3769,0.0326346511010878,3788,12,3812,0.00314795383001049,"low bq","NA"]
["UPN_Tr2_007",2,25470973,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu263Ala/c.788A>C",32729,1556,34460,0.0451538015089959,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.83,15.04,17253,15,17339,0.000865101793644386,15476,1541,17121,0.0900064248583611,"low bq","NA"]
["UPN_Tr2_071",2,25470980,"T","G","DNMT3A","ENST00000264709","missense_variant","Acg/Ccg|p.Thr261Pro/c.781A>C",5156,158,5335,0.0296157450796626,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.21,14.75,2689,3,2705,0.0011090573012939,2467,155,2630,0.05893536121673,"low bq","NA"]
["UPN_Tr2_061",2,25470988,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val258Glu/c.773T>A",1751,21,1780,0.0117977528089888,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,17.29,893,2,902,0.00221729490022173,858,19,878,0.0216400911161731,"low bq","NA"]
["UPN_Tr2_072",2,25470992,"T","G","DNMT3A","ENST00000264709","missense_variant","Act/Cct|p.Thr257Pro/c.769A>C",4139,127,4299,0.0295417538962549,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.36,16.16,2147,10,2176,0.00459558823529412,1992,117,2123,0.0551106924163919,"low bq","NA"]
["UPN_Tr2_060",2,25471015,"T","G","DNMT3A","ENST00000264709","missense_variant","cAg/cCg|p.Gln249Pro/c.746A>C",2214,27,2256,0.011968085106383,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.23,16.33,1126,2,1135,0.00176211453744493,1088,25,1121,0.0223015165031222,"low bq","NA"]
["UPN_Tr2_062",2,25471039,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu241Ala/c.722A>C",1535,24,1566,0.0153256704980843,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.49,14.58,0,0,0,"NA",1535,24,1566,0.0153256704980843,"low bq","NA"]
["UPN_Tr2_084",2,25497868,"T","G","DNMT3A","ENST00000264709","missense_variant","gAc/gCc|p.Asp194Ala/c.581A>C",836,33,872,0.0378440366972477,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.06,14.21,433,0,434,0,403,33,438,0.0753424657534247,"low bq","NA"]
["UPN_Tr2_061",2,25505348,"C","G","DNMT3A","ENST00000264709","missense_variant","tGc/tCc|p.Cys137Ser/c.410G>C",7590,82,7693,0.0106590406863382,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.87,14.41,3951,1,3959,0.000252589037635767,3639,81,3734,0.0216925549009106,"low bq","NA"]
["UPN_Tr2_066",2,25505352,"A","C","DNMT3A","ENST00000264709","missense_variant","Tgc/Ggc|p.Cys136Gly/c.406T>G",2813,57,2893,0.0197027307293467,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.19,14.68,1405,55,1471,0.0373895309313392,1408,2,1422,0.00140646976090014,"low bq","NA"]
["UPN_Tr2_064",2,25505358,"T","G","DNMT3A","ENST00000264709","missense_variant","Aat/Cat|p.Asn134His/c.400A>C",7010,79,7140,0.0110644257703081,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.77,14.09,3553,35,3618,0.00967385295743505,3457,44,3522,0.0124929017603634,"low bq","NA"]
["UPN_Tr2_053",2,25505363,"A","T","DNMT3A","ENST00000264709","missense_variant","gTg/gAg|p.Val132Glu/c.395T>A",30397,374,31077,0.0120346236766741,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.23,19.17,15480,63,15710,0.00401018459579885,14917,311,15367,0.0202381727077504,"low bq","NA"]
["UPN_Tr2_080",2,25505373,"A","C","DNMT3A","ENST00000264709","missense_variant","Tca/Gca|p.Ser129Ala/c.385T>G",10348,165,10590,0.0155807365439093,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.92,14.62,5215,75,5314,0.01411366202484,5133,90,5276,0.0170583775587566,"low bq","NA"]
["UPN_Tr2_055",2,25505377,"T","G","DNMT3A","ENST00000264709","missense_variant","gaA/gaC|p.Glu127Asp/c.381A>C",29723,623,30558,0.0203874599122979,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.83,15.19,14700,534,15344,0.0348018769551616,15023,89,15214,0.00584987511502563,"low bq","NA"]
["UPN_Tr2_080",2,25505378,"T","G","DNMT3A","ENST00000264709","missense_variant","gAa/gCa|p.Glu127Ala/c.380A>C",5232,177,5437,0.0325547176751885,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.77,14.55,149,7,158,0.0443037974683544,5083,170,5279,0.0322030687630233,"low bq","NA"]
["UPN_Tr2_084",2,25505388,"T","G","DNMT3A","ENST00000264709","missense_variant","Acc/Ccc|p.Thr124Pro/c.370A>C",4035,381,4443,0.0857528696826469,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",19.42,14.94,0,0,0,"NA",4035,381,4443,0.0857528696826469,"low bq","NA"]
["UPN_Tr2_048",2,25505402,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu119Ala/c.356A>C",18010,716,18808,0.0380689068481497,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.06,14.51,0,0,0,"NA",18010,716,18808,0.0380689068481497,"low bq","NA"]
["UPN_Tr2_096",2,25505402,"T","G","DNMT3A","ENST00000264709","missense_variant","gAg/gCg|p.Glu119Ala/c.356A>C",7918,373,8323,0.0448155713084224,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.52,14.42,0,0,0,"NA",7918,373,8323,0.0448155713084224,"low bq","NA"]
["UPN_Tr2_027",2,25536826,"C","G","DNMT3A","ENST00000264709","missense_variant","Ggg/Cgg|p.Gly10Arg/c.28G>C",10488,173,10684,0.0161924372894047,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NA","NO","NO","NA","NA",26.28,14.58,5413,1,5428,0.000184229918938836,5075,172,5256,0.0327245053272451,"low bq","NA"]
["UPN_Tr2_096",2,25536826,"C","G","DNMT3A","ENST00000264709","missense_variant","Ggg/Cgg|p.Gly10Arg/c.28G>C",7419,157,7588,0.0206905640484976,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NA","NO","NO","NA","NA",26.33,14.09,3835,0,3842,0,3584,157,3746,0.0419113721302723,"low bq","NA"]
["UPN_Tr2_044",2,25536852,"A","T","DNMT3A","ENST00000264709","start_lost","aTg/aAg|p.Met1?/c.2T>A",3511,52,3573,0.0145535964175763,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.38,14.77,1793,5,1805,0.00277008310249307,1718,47,1768,0.0265837104072398,"low bq","NA"]
["UPN_Tr2_091",2,198266552,"C","A","SF3B1","ENST00000335508","missense_variant","Gcc/Tcc|p.Ala762Ser/c.2284G>T",5071,53,5150,0.0102912621359223,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.93,14.25,2586,8,2602,0.00307455803228286,2485,45,2548,0.0176609105180534,"low bq","NA"]
["UPN_Tr2_078",2,198266564,"C","A","SF3B1","ENST00000335508","missense_variant","Gat/Tat|p.Asp758Tyr/c.2272G>T",9284,97,9450,0.0102645502645503,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.78,15.48,4687,54,4770,0.0113207547169811,4597,43,4680,0.00918803418803419,"low bq","NA"]
["UPN_Tr2_086",2,198266573,"G","T","SF3B1","ENST00000335508","missense_variant","Cct/Act|p.Pro755Thr/c.2263C>A",28532,290,28911,0.0100307841306077,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.16,14.27,14470,58,14575,0.00397941680960549,14062,232,14336,0.0161830357142857,"low bq","NA"]
["UPN_Tr2_070",2,198266709,"C","A","SF3B1","ENST00000335508","missense_variant","aaG/aaT|p.Lys741Asn/c.2223G>T",7491,93,7602,0.0122336227308603,0,0,0,0,1,0,0,0,1,"NO","NO","COSM1159841","haematopoietic_and_lymphoid_tissue",2,"NO","NO","NO","NO","NO","NO","NA","NA",31.29,15.01,7491,93,7602,0.0122336227308603,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_108",2,198266732,"C","A","SF3B1","ENST00000335508","missense_variant","Ggt/Tgt|p.Gly734Cys/c.2200G>T",10737,111,10865,0.0102162908421537,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.03,14.5,10737,111,10865,0.0102162908421537,0,0,0,"NA","low bq","NA"]
["UPN_Tr2_045",2,198266786,"C","A","SF3B1","ENST00000335508","missense_variant","Gca/Tca|p.Ala716Ser/c.2146G>T",30343,732,31312,0.0233776188042923,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.55,14.43,14478,713,15368,0.0463951067152525,15865,19,15944,0.00119167084796789,"low bq","NA"]
["UPN_Tr2_081",2,198266786,"C","A","SF3B1","ENST00000335508","missense_variant","Gca/Tca|p.Ala716Ser/c.2146G>T",12392,373,12813,0.0291110590806212,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.27,14.39,5868,367,6277,0.0584674207423929,6524,6,6536,0.000917992656058752,"low bq","NA"]
["UPN_Tr2_050",2,198267283,"G","T","SF3B1","ENST00000335508","missense_variant","Cat/Aat|p.His692Asn/c.2074C>A",2823,96,2924,0.0328317373461012,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.36,14.14,1219,92,1314,0.0700152207001522,1604,4,1610,0.00248447204968944,"low bq","NA"]
["UPN_Tr2_020",2,198267286,"C","A","SF3B1","ENST00000335508","stop_gained","Gaa/Taa|p.Glu691*/c.2071G>T",2565,213,2795,0.0762075134168157,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.46,14.06,1033,213,1252,0.170127795527157,1532,0,1543,0,"low bq","NA"]
["UPN_Tr2_062",2,198267286,"C","A","SF3B1","ENST00000335508","stop_gained","Gaa/Taa|p.Glu691*/c.2071G>T",2658,283,2943,0.0961603805640503,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.41,14.57,701,280,981,0.285423037716616,1957,3,1962,0.00152905198776758,"low bq","NA"]
["UPN_Tr2_077",2,198267286,"C","A","SF3B1","ENST00000335508","stop_gained","Gaa/Taa|p.Glu691*/c.2071G>T",4103,375,4490,0.0835189309576837,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.62,14.59,1100,374,1478,0.253044654939107,3003,1,3012,0.000332005312084993,"low bq","NA"]
["UPN_Tr2_075",2,198267294,"T","A","SF3B1","ENST00000335508","missense_variant","gAa/gTa|p.Glu688Val/c.2063A>T",6962,103,7092,0.0145234066553864,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.82,20.71,2074,80,2161,0.03701989819528,4888,23,4931,0.00466436828229568,"low bq","NA"]
["UPN_Tr2_054",2,198267295,"C","A","SF3B1","ENST00000335508","stop_gained","Gaa/Taa|p.Glu688*/c.2062G>T",3225,354,3586,0.0987172336865588,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.4,14.59,1151,350,1505,0.232558139534884,2074,4,2081,0.00192215281114849,"low bq","NA"]
["UPN_Tr2_108",2,198267295,"C","A","SF3B1","ENST00000335508","stop_gained","Gaa/Taa|p.Glu688*/c.2062G>T",3639,336,3980,0.0844221105527638,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.95,14.9,592,335,927,0.361380798274002,3047,1,3053,0.000327546675401245,"low bq","NA"]
["UPN_Tr2_057",2,198267298,"C","A","SF3B1","ENST00000335508","missense_variant","Gtt/Ttt|p.Val687Phe/c.2059G>T",4001,256,4263,0.0600516068496364,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.64,14.45,1523,255,1779,0.143338954468803,2478,1,2484,0.000402576489533011,"low bq","NA"]
["UPN_Tr2_018",2,198267299,"T","A","SF3B1","ENST00000335508","missense_variant","ttA/ttT|p.Leu686Phe/c.2058A>T",3404,96,3512,0.0273348519362187,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.13,15.04,1335,92,1433,0.0642009769713887,2069,4,2079,0.00192400192400192,"low bq","NA"]
["UPN_Tr2_064",2,198267299,"T","A","SF3B1","ENST00000335508","missense_variant","ttA/ttT|p.Leu686Phe/c.2058A>T",2202,59,2270,0.0259911894273128,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.17,15.12,572,57,632,0.0901898734177215,1630,2,1638,0.00122100122100122,"low bq","NA"]
["UPN_Tr2_025",2,198267303,"C","A","SF3B1","ENST00000335508","missense_variant","aGt/aTt|p.Ser685Ile/c.2054G>T",6138,337,6480,0.0520061728395062,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.47,14.04,2293,337,2633,0.127990884922142,3845,0,3847,0,"low bq","NA"]
["UPN_Tr2_034",2,198267305,"T","A","SF3B1","ENST00000335508","missense_variant","agA/agT|p.Arg684Ser/c.2052A>T",1430,27,1458,0.0185185185185185,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.73,18.04,569,23,593,0.0387858347386172,861,4,865,0.0046242774566474,"low bq","NA"]
["UPN_Tr2_018",2,198267306,"C","A","SF3B1","ENST00000335508","missense_variant","aGa/aTa|p.Arg684Ile/c.2051G>T",3142,230,3375,0.0681481481481482,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.86,14.18,1068,226,1296,0.174382716049383,2074,4,2079,0.00192400192400192,"low bq","NA"]
["UPN_Tr2_064",2,198267306,"C","A","SF3B1","ENST00000335508","missense_variant","aGa/aTa|p.Arg684Ile/c.2051G>T",2095,100,2197,0.0455166135639508,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.15,14.39,458,100,559,0.178890876565295,1637,0,1638,0,"low bq","NA"]
["UPN_Tr2_026",2,198267307,"T","A","SF3B1","ENST00000335508","stop_gained","Aga/Tga|p.Arg684*/c.2050A>T",5796,156,5964,0.0261569416498994,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.5,15.74,2188,149,2342,0.0636208368915457,3608,7,3622,0.00193263390392049,"low bq","NA"]
["UPN_Tr2_110",2,198267310,"G","A","SF3B1","ENST00000335508","missense_variant","Ctt/Ttt|p.Leu683Phe/c.2047C>T",3307,56,3407,0.0164367478720282,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.65,15.46,59,54,151,0.357615894039735,3248,2,3256,0.000614250614250614,"low bq","NA"]
["UPN_Tr2_077",2,198267310,"G","T","SF3B1","ENST00000335508","missense_variant","Ctt/Att|p.Leu683Ile/c.2047C>A",3080,36,3177,0.0113314447592068,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.04,14,69,35,163,0.214723926380368,3011,1,3014,0.00033178500331785,"low bq","NA"]
["UPN_Tr2_060",2,198267444,"G","T","SF3B1","ENST00000335508","missense_variant","gCc/gAc|p.Ala638Asp/c.1913C>A",10906,134,11078,0.0120960462177288,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.92,16.46,5456,36,5524,0.00651701665459812,5450,98,5554,0.0176449405833633,"low bq","NA"]
["UPN_Tr2_067",2,209113154,"G","T","IDH1","ENST00000345146","missense_variant","cCc/cAc|p.Pro118His/c.353C>A",37064,432,37690,0.0114619262403821,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.14,14.47,19020,53,19211,0.00275883608349383,18044,379,18479,0.0205097678445803,"low bq","NA"]
["UPN_Tr2_057",2,209113233,"A","T","IDH1","ENST00000345146","missense_variant","Tgg/Agg|p.Trp92Arg/c.274T>A",11197,143,11393,0.0125515667515141,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.19,20.78,0,0,0,"NA",11197,143,11393,0.0125515667515141,"low bq","NA"]
["UPN_Tr2_073",4,106155076,"G","T","TET2","ENST00000380013","5_prime_UTR_premature_start_codon_gain_variant","|c.-24G>T",4028,115,4154,0.0276841598459316,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.04,15.01,2793,113,2913,0.0387916237555784,1235,2,1241,0.0016116035455278,"low bq","NA"]
["UPN_Tr2_059",4,106155666,"T","G","TET2","ENST00000380013","missense_variant","agT/agG|p.Ser189Arg/c.567T>G",33455,382,34007,0.0112329814449966,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.35,15.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066",4,106155832,"A","C","TET2","ENST00000380013","missense_variant","Acc/Ccc|p.Thr245Pro/c.733A>C",66787,1220,68239,0.0178783393660517,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.58,18.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_037",4,106156252,"T","A","TET2","ENST00000380013","missense_variant","Tca/Aca|p.Ser385Thr/c.1153T>A",18763,230,19288,0.0119245126503526,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.56,15.53,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087",4,106156252,"T","C","TET2","ENST00000380013","missense_variant","Tca/Cca|p.Ser385Pro/c.1153T>C",27445,567,30135,0.018815331010453,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.11,15.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",4,106156252,"T","G","TET2","ENST00000380013","missense_variant","Tca/Gca|p.Ser385Ala/c.1153T>G",18879,1380,20765,0.0664579821815555,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.03,15.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",4,106156258,"T","G","TET2","ENST00000380013","missense_variant","Ttc/Gtc|p.Phe387Val/c.1159T>G",13088,149,13494,0.0110419445679561,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.53,14.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_097",4,106156560,"G","T","TET2","ENST00000380013","missense_variant","agG/agT|p.Arg487Ser/c.1461G>T",29302,317,29645,0.0106932029009951,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.64,14.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",4,106157096,"A","C","TET2","ENST00000380013","missense_variant","gAc/gCc|p.Asp666Ala/c.1997A>C",34695,666,35456,0.018783844765343,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.36,14.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_045",4,106157202,"G","T","TET2","ENST00000380013","missense_variant","caG/caT|p.Gln701His/c.2103G>T",12533,137,12831,0.0106772659964149,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.1,14.56,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_103",4,106157202,"G","T","TET2","ENST00000380013","missense_variant","caG/caT|p.Gln701His/c.2103G>T",14017,191,14419,0.0132464109855052,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.14,14.83,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",4,106157847,"G","T","TET2","ENST00000380013","missense_variant","caG/caT|p.Gln916His/c.2748G>T",2031,34,2107,0.0161366872330327,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.85,14.59,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",4,106157876,"A","C","TET2","ENST00000380013","missense_variant","aAt/aCt|p.Asn926Thr/c.2777A>C",1437,52,1501,0.0346435709526982,0,0,0,0,1,0,0,0,1,0.0116,"NO","NO","NO","O","NO","rs373958593","NO",8.237E-006,"NO","NO","NA","NA",28.09,14.75,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",4,106158094,"G","A","TET2","ENST00000380013","missense_variant","Gaa/Aaa|p.Glu999Lys/c.2995G>A",35127,450,36701,0.0122612462875671,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.48,17.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_010",4,106158094,"G","C","TET2","ENST00000380013","missense_variant","Gaa/Caa|p.Glu999Gln/c.2995G>C",38055,557,39151,0.0142269673826978,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.41,14.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_094",4,106158094,"G","C","TET2","ENST00000380013","missense_variant","Gaa/Caa|p.Glu999Gln/c.2995G>C",23315,760,24220,0.0313790255986788,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28,14.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_053",4,106158438,"T","A","TET2","ENST00000380013","missense_variant","gaT/gaA|p.Asp1113Glu/c.3339T>A",25932,887,26880,0.0329985119047619,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.25,15.83,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_107",4,106158438,"T","A","TET2","ENST00000380013","missense_variant","gaT/gaA|p.Asp1113Glu/c.3339T>A",21052,318,21412,0.0148514851485149,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.11,14.73,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",4,106162522,"C","A","TET2","ENST00000380013","missense_variant","Cct/Act|p.Pro1146Thr/c.3436C>A",24848,271,25185,0.0107603732380385,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.41,14.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086",4,106162532,"C","A","TET2","ENST00000380013","missense_variant","aCc/aAc|p.Thr1149Asn/c.3446C>A",20713,260,21094,0.0123257798426093,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.45,15.28,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088",4,106162544,"C","A","TET2","ENST00000380013","missense_variant","gCa/gAa|p.Ala1153Glu/c.3458C>A",26701,302,27115,0.011137746634704,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.82,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087",4,106164029,"T","G","TET2","ENST00000380013","missense_variant","gTc/gGc|p.Val1180Gly/c.3539T>G",57358,1174,58839,0.0199527524261119,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.35,17.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085",4,106164816,"T","G","TET2","ENST00000380013","missense_variant","atT/atG|p.Ile1228Met/c.3684T>G",2982,41,3042,0.0134779750164366,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.83,16.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067",4,106164847,"T","G","TET2","ENST00000380013","missense_variant","Tct/Gct|p.Ser1239Ala/c.3715T>G",2673,29,2712,0.010693215339233,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.29,14.93,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_039",4,106164851,"T","G","TET2","ENST00000380013","missense_variant","cTg/cGg|p.Leu1240Arg/c.3719T>G",22741,630,23506,0.026801667659321,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.04,15.13,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_106",4,106164851,"T","G","TET2","ENST00000380013","missense_variant","cTg/cGg|p.Leu1240Arg/c.3719T>G",13346,275,13680,0.0201023391812865,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.79,14.88,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_034",4,106180855,"T","A","TET2","ENST00000380013","missense_variant","Tac/Aac|p.Tyr1295Asn/c.3883T>A",6073,69,6154,0.0112122196945076,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,15.07,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_015",4,106190885,"T","A","TET2","ENST00000380013","missense_variant","aTg/aAg|p.Met1388Lys/c.4163T>A",15597,168,15844,0.0106033829840949,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.78,16.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",4,106190899,"A","T","TET2","ENST00000380013","missense_variant","Aca/Tca|p.Thr1393Ser/c.4177A>T",6174,77,6277,0.0122670065317827,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.45,15.73,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",4,106193855,"A","T","TET2","ENST00000380013","missense_variant","aaA/aaT|p.Lys1439Asn/c.4317A>T",9933,103,10152,0.0101457840819543,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.42,15.18,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067",4,106194051,"G","T","TET2","ENST00000380013","missense_variant","Gca/Tca|p.Ala1505Ser/c.4513G>T",15177,170,15382,0.0110518788193993,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NA","NO","NO","NA","NA",30.33,15.04,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_041",4,106196296,"A","C","TET2","ENST00000380013","missense_variant","agA/agC|p.Arg1543Ser/c.4629A>C",4045,47,4115,0.0114216281895504,0,0,0,0,1,0,0,1,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.58,26.53,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_036",4,106196302,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln1545His/c.4635G>C",8493,150,8681,0.0172791153092962,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.75,17.15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_101",4,106196302,"G","C","TET2","ENST00000380013","missense_variant","caG/caC|p.Gln1545His/c.4635G>C",3375,190,3579,0.0530874545962559,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.13,15.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_027",4,106196317,"T","A","TET2","ENST00000380013","missense_variant","caT/caA|p.His1550Gln/c.4650T>A",8221,95,8347,0.0113813346112376,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.16,17.68,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011",4,106196319,"A","C","TET2","ENST00000380013","missense_variant","cAc/cCc|p.His1551Pro/c.4652A>C",7492,117,7653,0.0152881223049784,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.66,15.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",4,106196327,"A","C","TET2","ENST00000380013","missense_variant","Aca/Cca|p.Thr1554Pro/c.4660A>C",1484,21,1514,0.0138705416116248,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.55,17.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",4,106196342,"T","A","TET2","ENST00000380013","missense_variant","Tct/Act|p.Ser1559Thr/c.4675T>A",1833,26,1866,0.0139335476956056,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.99,17.04,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_015",4,106196347,"T","A","TET2","ENST00000380013","stop_gained","taT/taA|p.Tyr1560*/c.4680T>A",12113,167,12342,0.0135310322476098,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.82,15.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",4,106196347,"T","A","TET2","ENST00000380013","stop_gained","taT/taA|p.Tyr1560*/c.4680T>A",1194,26,1229,0.0211554109031733,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.37,14.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",4,106196363,"A","C","TET2","ENST00000380013","missense_variant","Acc/Ccc|p.Thr1566Pro/c.4696A>C",14702,152,14959,0.0101611070258707,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.39,14.59,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_025",4,106196368,"T","A","TET2","ENST00000380013","missense_variant","aaT/aaA|p.Asn1567Lys/c.4701T>A",11067,147,11264,0.0130504261363636,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.97,16.52,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_001",4,106196377,"G","T","TET2","ENST00000380013","missense_variant","atG/atT|p.Met1570Ile/c.4710G>T",8292,124,8451,0.0146728197846409,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.92,14.33,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_104",4,106196377,"G","T","TET2","ENST00000380013","missense_variant","atG/atT|p.Met1570Ile/c.4710G>T",14837,163,15157,0.0107541070132612,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.8,14.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078",4,106197177,"C","G","TET2","ENST00000380013","missense_variant","gCt/gGt|p.Ala1837Gly/c.5510C>G",13646,253,13929,0.0181635436858353,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.4,14.48,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",4,106197204,"T","G","TET2","ENST00000380013","missense_variant","gTc/gGc|p.Val1846Gly/c.5537T>G",30592,1040,31826,0.0326776849117074,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.11,15.05,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",4,106197258,"T","G","TET2","ENST00000380013","missense_variant","gTg/gGg|p.Val1864Gly/c.5591T>G",10818,172,11050,0.0155656108597285,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.95,14.55,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_045",4,106197513,"T","A","TET2","ENST00000380013","missense_variant","gTg/gAg|p.Val1949Glu/c.5846T>A",5573,57,5658,0.0100742311770944,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.85,19.26,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",4,106197538,"T","A","TET2","ENST00000380013","missense_variant","caT/caA|p.His1957Gln/c.5871T>A",7550,87,7678,0.0113310758009898,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.56,18.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",4,106197549,"A","C","TET2","ENST00000380013","missense_variant","gAg/gCg|p.Glu1961Ala/c.5882A>C",5748,96,5873,0.0163459901242976,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.38,14.85,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_101",4,106197549,"A","C","TET2","ENST00000380013","missense_variant","gAg/gCg|p.Glu1961Ala/c.5882A>C",3961,52,4024,0.0129224652087475,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.76,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_057",4,106197557,"T","A","TET2","ENST00000380013","missense_variant","Tac/Aac|p.Tyr1964Asn/c.5890T>A",7849,102,7989,0.0127675553886594,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.2,15.06,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_059",4,106197590,"A","C","TET2","ENST00000380013","missense_variant","Acc/Ccc|p.Thr1975Pro/c.5923A>C",10212,163,10411,0.0156565171453271,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.22,14.17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_037",7,148504738,"T","A","EZH2","ENST00000320356","stop_lost","tgA/tgT|p.Ter752Cysext*?/c.2256A>T",9313,109,9457,0.011525853864862,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.14,16.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_033",7,148504747,"T","A","EZH2","ENST00000320356","missense_variant","gaA/gaT|p.Glu749Asp/c.2247A>T",5939,81,6045,0.0133995037220844,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.38,17.26,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108",7,148504750,"C","A","EZH2","ENST00000320356","missense_variant","atG/atT|p.Met748Ile/c.2244G>T",849,34,886,0.0383747178329571,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.91,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",7,148504753,"T","A","EZH2","ENST00000320356","missense_variant","gaA/gaT|p.Glu747Asp/c.2241A>T",8101,124,8260,0.0150121065375303,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.57,16.02,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_014",7,148504756,"T","A","EZH2","ENST00000320356","missense_variant","agA/agT|p.Arg746Ser/c.2238A>T",8424,88,8539,0.0103056564000468,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.99,15.16,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",7,148504758,"T","A","EZH2","ENST00000320356","stop_gained","Aga/Tga|p.Arg746*/c.2236A>T",10007,130,10187,0.0127613625208599,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.45,16.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_010",7,148504759,"T","A","EZH2","ENST00000320356","missense_variant","gaA/gaT|p.Glu745Asp/c.2235A>T",10557,293,10883,0.026922723513737,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.28,14.52,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",7,148504764,"T","A","EZH2","ENST00000320356","missense_variant","Atc/Ttc|p.Ile744Phe/c.2230A>T",9103,190,9325,0.0203753351206434,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.88,15.39,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",7,148504767,"C","A","EZH2","ENST00000320356","missense_variant","Ggc/Tgc|p.Gly743Cys/c.2227G>T",5136,93,5260,0.017680608365019,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",22.85,14.28,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_006",7,148504772,"T","A","EZH2","ENST00000320356","missense_variant","tAt/tTt|p.Tyr741Phe/c.2222A>T",5518,57,5591,0.0101949561795743,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.5,15.86,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_053",7,148504775,"T","A","EZH2","ENST00000320356","missense_variant","aAg/aTg|p.Lys740Met/c.2219A>T",8601,173,8810,0.0196367763904654,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.27,17.06,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_017",7,148504784,"T","A","EZH2","ENST00000320356","missense_variant","gAt/gTt|p.Asp737Val/c.2210A>T",3270,57,3337,0.0170812106682649,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.39,15.02,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",7,148504789,"C","A","EZH2","ENST00000320356","missense_variant","caG/caT|p.Gln735His/c.2205G>T",8013,180,8205,0.0219378427787934,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.23,14.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_021",7,148504791,"G","C","EZH2","ENST00000320356","missense_variant","Cag/Gag|p.Gln735Glu/c.2203C>G",6003,69,6111,0.0112911143838979,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",15.74,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_046",7,148504793,"C","A","EZH2","ENST00000320356","missense_variant","aGc/aTc|p.Ser734Ile/c.2201G>T",10697,154,10859,0.0141817846947233,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.96,14.61,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",7,148504794,"T","A","EZH2","ENST00000320356","missense_variant","Agc/Tgc|p.Ser734Cys/c.2200A>T",6488,190,6708,0.0283243887895051,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.18,14.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_037",7,148504795,"G","C","EZH2","ENST00000320356","stop_gained","taC/taG|p.Tyr733*/c.2199C>G",9270,124,9439,0.0131369848500901,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",16.47,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088",7,148504795,"G","C","EZH2","ENST00000320356","stop_gained","taC/taG|p.Tyr733*/c.2199C>G",842,22,870,0.0252873563218391,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",18.21,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_025",7,148506437,"G","T","EZH2","ENST00000320356","missense_variant","gCa/gAa|p.Ala692Glu/c.2075C>A",26888,570,27526,0.0207076945433408,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.86,14.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_072",7,148506437,"G","T","EZH2","ENST00000320356","missense_variant","gCa/gAa|p.Ala692Glu/c.2075C>A",10701,250,10987,0.0227541640120142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.11,15.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",7,148508773,"T","A","EZH2","ENST00000320356","missense_variant","Att/Ttt|p.Ile631Phe/c.1891A>T",12907,405,13373,0.0302849024153144,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.78,14.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078",7,148508773,"T","A","EZH2","ENST00000320356","missense_variant","Att/Ttt|p.Ile631Phe/c.1891A>T",17855,188,18116,0.0103775667917863,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.79,15.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",7,148511139,"T","G","EZH2","ENST00000320356","missense_variant","gAc/gCc|p.Asp588Ala/c.1763A>C",18402,489,18985,0.0257571767184619,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.4,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",7,148511176,"A","T","EZH2","ENST00000320356","missense_variant","Tgc/Agc|p.Cys576Ser/c.1726T>A",7983,138,8154,0.0169242089771891,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.23,17.26,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",7,148511191,"A","T","EZH2","ENST00000320356","missense_variant","Tgc/Agc|p.Cys571Ser/c.1711T>A",8081,117,8245,0.0141904184354154,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.6,16.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_109",7,148512126,"A","C","EZH2","ENST00000320356","missense_variant","Tcc/Gcc|p.Ser518Ala/c.1552T>G",26797,553,27485,0.0201200654902674,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.15,14.33,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_032",7,148515044,"C","G","EZH2","ENST00000320356","missense_variant","Gca/Cca|p.Ala389Pro/c.1165G>C",4325,52,4398,0.0118235561618918,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.03,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_094",7,148515044,"C","G","EZH2","ENST00000320356","missense_variant","Gca/Cca|p.Ala389Pro/c.1165G>C",10762,251,11073,0.0226677503838165,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.74,14.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085",7,148515054,"A","T","EZH2","ENST00000320356","missense_variant","agT/agA|p.Ser385Arg/c.1155T>A",5957,62,6045,0.0102564102564103,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.36,16.06,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_018",7,148515089,"T","G","EZH2","ENST00000320356","missense_variant","Acc/Ccc|p.Thr374Pro/c.1120A>C",7551,149,7737,0.0192581103786998,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.48,18.25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_074",7,148515089,"T","G","EZH2","ENST00000320356","missense_variant","Acc/Ccc|p.Thr374Pro/c.1120A>C",3748,55,3819,0.0144016758313695,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.34,15.98,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_058",7,148515108,"A","T","EZH2","ENST00000320356","missense_variant","agT/agA|p.Ser367Arg/c.1101T>A",5326,69,5422,0.0127259313906308,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.7,16.96,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_069",7,148515114,"A","T","EZH2","ENST00000320356","missense_variant","aaT/aaA|p.Asn365Lys/c.1095T>A",3616,41,3669,0.0111747070046334,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.29,15.39,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_077",7,148523664,"G","T","EZH2","ENST00000320356","missense_variant","aaC/aaA|p.Asn263Lys/c.789C>A",33207,349,33608,0.010384432278029,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.17,15.15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_019",7,148525952,"C","A","EZH2","ENST00000320356","stop_gained","Gaa/Taa|p.Glu169*/c.505G>T",8899,1113,10030,0.110967098703888,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.86,14.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",7,148525952,"C","A","EZH2","ENST00000320356","stop_gained","Gaa/Taa|p.Glu169*/c.505G>T",19231,1137,20409,0.0557107158606497,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.65,15.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_020",7,148526900,"C","A","EZH2","ENST00000320356","missense_variant","gGa/gTa|p.Gly135Val/c.404G>T",12022,166,12226,0.0135776214624571,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,14.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",7,148526900,"C","A","EZH2","ENST00000320356","missense_variant","gGa/gTa|p.Gly135Val/c.404G>T",29587,721,30484,0.023651751738617,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.41,14.93,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",7,148526909,"G","T","EZH2","ENST00000320356","missense_variant","cCt/cAt|p.Pro132His/c.395C>A",12868,141,13062,0.0107946715663757,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.57,15.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",7,148529735,"C","A","EZH2","ENST00000320356","missense_variant","caG/caT|p.Gln118His/c.354G>T",3008,31,3042,0.0101906640368179,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.4,17.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087",7,148529738,"C","A","EZH2","ENST00000320356","missense_variant","caG/caT|p.Gln117His/c.351G>T",7818,153,7976,0.0191825476429288,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.29,14.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_110",7,148529751,"C","A","EZH2","ENST00000320356","missense_variant","tGg/tTg|p.Trp113Leu/c.338G>T",3601,46,3650,0.0126027397260274,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.11,15.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011",7,148529782,"C","A","EZH2","ENST00000320356","missense_variant","Gca/Tca|p.Ala103Ser/c.307G>T",14133,298,14480,0.0205801104972376,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.68,14.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_110",7,148529782,"C","A","EZH2","ENST00000320356","missense_variant","Gca/Tca|p.Ala103Ser/c.307G>T",6873,150,7044,0.0212947189097104,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.97,15.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086",7,148543628,"C","A","EZH2","ENST00000320356","missense_variant","tgG/tgT|p.Trp60Cys/c.180G>T",3188,38,3243,0.0117175454825779,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.71,17.61,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_012",7,148543636,"G","T","EZH2","ENST00000320356","missense_variant","Caa/Aaa|p.Gln58Lys/c.172C>A",5303,107,5429,0.0197089703444465,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.74,15.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080",7,148543641,"A","T","EZH2","ENST00000320356","stop_gained","tTa/tAa|p.Leu56*/c.167T>A",2929,37,2987,0.012387010378306,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.67,18.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",7,148543645,"T","A","EZH2","ENST00000320356","missense_variant","Atc/Ttc|p.Ile55Phe/c.163A>T",1827,36,1865,0.0193029490616622,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.74,15.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_102",7,148543648,"C","A","EZH2","ENST00000320356","stop_gained","Gaa/Taa|p.Glu54*/c.160G>T",8015,82,8133,0.0100823804254273,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.12,14.48,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_099",7,148543650,"G","T","EZH2","ENST00000320356","missense_variant","aCg/aAg|p.Thr53Lys/c.158C>A",6178,172,6368,0.0270100502512563,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.43,16.16,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",7,148543655,"T","A","EZH2","ENST00000320356","missense_variant","gaA/gaT|p.Glu51Asp/c.153A>T",6845,71,6931,0.010243832058866,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,15.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",7,148543658,"C","A","EZH2","ENST00000320356","missense_variant","ttG/ttT|p.Leu50Phe/c.150G>T",14014,143,14177,0.010086760245468,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.86,18.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087",7,148543666,"T","A","EZH2","ENST00000320356","stop_gained","Aaa/Taa|p.Lys48*/c.142A>T",18642,308,19014,0.0161985905122541,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.38,15.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_102",7,148543667,"C","A","EZH2","ENST00000320356","missense_variant","caG/caT|p.Gln47His/c.141G>T",4004,49,4074,0.0120274914089347,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.01,15.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_093",7,148543669,"G","T","EZH2","ENST00000320356","missense_variant","Cag/Aag|p.Gln47Lys/c.139C>A",2561,104,2670,0.0389513108614232,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.85,15.4,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_020",7,148543672,"G","T","EZH2","ENST00000320356","missense_variant","Cgt/Agt|p.Arg46Ser/c.136C>A",4276,65,4358,0.0149150986691143,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.99,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108",7,148543672,"G","T","EZH2","ENST00000320356","missense_variant","Cgt/Agt|p.Arg46Ser/c.136C>A",5248,139,5421,0.0256410256410256,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.19,14.53,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084",7,148543673,"A","C","EZH2","ENST00000320356","missense_variant","aaT/aaG|p.Asn45Lys/c.135T>G",8714,130,9195,0.0141381185426862,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.12,14.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_024",7,148543677,"G","T","EZH2","ENST00000320356","missense_variant","tCc/tAc|p.Ser44Tyr/c.131C>A",2761,35,2803,0.0124866214769889,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.238E-006,"NO","NO","NA","NA",28.9,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_096",7,148543677,"G","T","EZH2","ENST00000320356","missense_variant","tCc/tAc|p.Ser44Tyr/c.131C>A",3195,74,3275,0.0225954198473282,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.238E-006,"NO","NO","NA","NA",28.95,14.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_040",7,148543678,"A","T","EZH2","ENST00000320356","missense_variant","Tcc/Acc|p.Ser44Thr/c.130T>A",5416,92,5530,0.0166365280289331,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.24,16.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",7,148543680,"C","A","EZH2","ENST00000320356","missense_variant","aGt/aTt|p.Ser43Ile/c.128G>T",6881,82,6977,0.0117529023935789,0,0,0,0,1,0,0,0,1,"NO","NO","COSM3879126, COSM3879127","stomach",2,"NO","NO","NO","NO","NO","NO","NA","NA",31.59,14.17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",7,148543681,"T","A","EZH2","ENST00000320356","missense_variant","Agt/Tgt|p.Ser43Cys/c.127A>T",3495,50,3559,0.0140488901376791,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.09,14.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_027",7,148543685,"C","A","EZH2","ENST00000320356","missense_variant","atG/atT|p.Met41Ile/c.123G>T",8542,128,8700,0.0147126436781609,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.23,14.51,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_111",7,148543685,"C","A","EZH2","ENST00000320356","missense_variant","atG/atT|p.Met41Ile/c.123G>T",5779,122,5929,0.020576825771631,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.39,14.2,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_046",7,148544350,"C","A","EZH2","ENST00000320356","missense_variant","tGt/tTt|p.Cys14Phe/c.41G>T",2020,50,2080,0.0240384615384615,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.36,14.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_092",7,148544350,"C","A","EZH2","ENST00000320356","missense_variant","tGt/tTt|p.Cys14Phe/c.41G>T",6266,142,6419,0.0221218258295685,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,14.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",9,5069973,"C","A","JAK2","ENST00000381652","missense_variant","cCa/cAa|p.Pro521Gln/c.1562C>A",6409,92,6531,0.0140866636043485,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.59,16.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_102",9,5069987,"T","A","JAK2","ENST00000381652","missense_variant","Tta/Ata|p.Leu526Ile/c.1576T>A",6316,95,6438,0.0147561354457906,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.01,15.44,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_009",9,5070023,"C","A","JAK2","ENST00000381652","missense_variant","Cac/Aac|p.His538Asn/c.1612C>A",9033,277,9328,0.0296955403087479,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.33,15.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_111",9,5070023,"C","A","JAK2","ENST00000381652","missense_variant","Cac/Aac|p.His538Asn/c.1612C>A",7855,216,8081,0.026729365177577,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.97,15.91,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062",9,5073727,"C","A","JAK2","ENST00000381652","missense_variant","agC/agA|p.Ser602Arg/c.1806C>A",5957,69,6033,0.0114370959721532,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.99,14.77,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011",9,5073731,"C","A","JAK2","ENST00000381652","missense_variant","Ctt/Att|p.Leu604Ile/c.1810C>A",18195,311,18537,0.0167772562982144,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.81,14.43,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",9,5073735,"C","A","JAK2","ENST00000381652","missense_variant","tCt/tAt|p.Ser605Tyr/c.1814C>A",19752,621,20426,0.0304024282776853,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.82,14.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108",9,5073735,"C","A","JAK2","ENST00000381652","missense_variant","tCt/tAt|p.Ser605Tyr/c.1814C>A",8537,132,8731,0.0151185431222082,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.45,14.22,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",9,5073739,"C","A","JAK2","ENST00000381652","missense_variant","caC/caA|p.His606Gln/c.1818C>A",24113,297,24676,0.0120359863835306,0,0,0,0,1,0,0,0,1,0.0116,"NO","COSM29116","haematopoietic_and_lymphoid_tissue",1,"NO","rs145561071","NO",2.471E-005,"NO","NO","NA","NA",28.26,14.87,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_100",9,5073743,"C","A","JAK2","ENST00000381652","missense_variant","Cat/Aat|p.His608Asn/c.1822C>A",10515,112,10672,0.0104947526236882,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.71,14.72,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063",9,5073762,"G","T","JAK2","ENST00000381652","missense_variant","gGa/gTa|p.Gly614Val/c.1841G>T",13183,160,13376,0.0119617224880383,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.1,14.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_074",9,5073776,"G","T","JAK2","ENST00000381652","stop_gained","Gga/Tga|p.Gly619*/c.1855G>T",13753,141,13955,0.0101039054102472,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.43,14.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",11,119148903,"G","T","CBL","ENST00000264033","missense_variant","Ggc/Tgc|p.Gly375Cys/c.1123G>T",17489,263,17789,0.0147844173365563,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.54,14.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085",11,119148907,"C","A","CBL","ENST00000264033","missense_variant","tCc/tAc|p.Ser376Tyr/c.1127C>A",56792,602,57623,0.0104472172569981,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.69,15.44,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_090",11,119148934,"C","A","CBL","ENST00000264033","missense_variant","gCt/gAt|p.Ala385Asp/c.1154C>A",8457,100,8580,0.0116550116550117,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.49,14.51,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_094",11,119148934,"C","A","CBL","ENST00000264033","missense_variant","gCt/gAt|p.Ala385Asp/c.1154C>A",9458,114,9584,0.0118948247078464,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.57,15.06,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_009",12,11905477,"A","T","ETV6","ENST00000396373","missense_variant","Atg/Ttg|p.Met43Leu/c.127A>T",19532,334,19948,0.0167435331862843,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.57,15.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011",12,11905478,"T","G","ETV6","ENST00000396373","missense_variant","aTg/aGg|p.Met43Arg/c.128T>G",11458,242,11747,0.0206010045117902,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.83,14.17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",12,11905481,"A","T","ETV6","ENST00000396373","missense_variant","gAg/gTg|p.Glu44Val/c.131A>T",16297,207,16630,0.0124473842453397,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.42,16.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_048",12,11905485,"A","T","ETV6","ENST00000396373","missense_variant","gaA/gaT|p.Glu45Asp/c.135A>T",6215,144,6423,0.0224194301728164,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.51,14.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_106",12,11905487,"A","C","ETV6","ENST00000396373","missense_variant","gAc/gCc|p.Asp46Ala/c.137A>C",10858,111,11028,0.0100652883569097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.94,14.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_044",12,11905508,"A","T","ETV6","ENST00000396373","missense_variant","cAc/cTc|p.His53Leu/c.158A>T",1511,32,1550,0.0206451612903226,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.92,15.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",12,11905509,"C","G","ETV6","ENST00000396373","missense_variant","caC/caG|p.His53Gln/c.159C>G",3384,36,3424,0.0105140186915888,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.88,14.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108",12,11905510,"C","G","ETV6","ENST00000396373","missense_variant","Ctg/Gtg|p.Leu54Val/c.160C>G",2818,55,2877,0.0191171359054571,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.28,14.4,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_049",12,11992206,"A","T","ETV6","ENST00000396373","missense_variant","aAa/aTa|p.Lys99Ile/c.296A>T",9684,134,9855,0.0135971588026383,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.11,18.06,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",12,12022403,"A","C","ETV6","ENST00000396373","missense_variant","cAc/cCc|p.His170Pro/c.509A>C",2603,33,2654,0.0124340617935192,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.65,15.21,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_083",12,12022417,"A","C","ETV6","ENST00000396373","missense_variant","Acc/Ccc|p.Thr175Pro/c.523A>C",5733,62,5818,0.0106565830182193,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.38,15.24,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",12,12022451,"T","A","ETV6","ENST00000396373","missense_variant","aTc/aAc|p.Ile186Asn/c.557T>A",6367,66,6461,0.0102151369757004,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.39,17.45,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",12,12022456,"A","C","ETV6","ENST00000396373","missense_variant","Aca/Cca|p.Thr188Pro/c.562A>C",9086,137,9282,0.0147597500538677,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27,14.52,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",12,12022460,"A","C","ETV6","ENST00000396373","missense_variant","aAt/aCt|p.Asn189Thr/c.566A>C",15612,219,15959,0.0137226643273388,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.38,14.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_072",12,12022463,"A","C","ETV6","ENST00000396373","missense_variant","cAc/cCc|p.His190Pro/c.569A>C",11289,383,11731,0.0326485380615463,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.89,14.75,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_042",12,12022478,"A","C","ETV6","ENST00000396373","missense_variant","gAc/gCc|p.Asp195Ala/c.584A>C",17768,314,18186,0.0172660288133729,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.56,14.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088",12,12022478,"A","C","ETV6","ENST00000396373","missense_variant","gAc/gCc|p.Asp195Ala/c.584A>C",8851,311,9203,0.0337933282625231,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.24,15.13,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",12,12022487,"A","C","ETV6","ENST00000396373","missense_variant","cAg/cCg|p.Gln198Pro/c.593A>C",4940,80,5048,0.0158478605388273,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,14.91,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_046",12,12022627,"T","A","ETV6","ENST00000396373","missense_variant","Tgc/Agc|p.Cys245Ser/c.733T>A",9637,99,9775,0.0101278772378517,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.96,18.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",12,12022649,"A","C","ETV6","ENST00000396373","missense_variant","cAc/cCc|p.His252Pro/c.755A>C",16464,2698,19271,0.140003113486586,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.55,15.07,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_069",12,12022654,"A","C","ETV6","ENST00000396373","missense_variant","Aag/Cag|p.Lys254Gln/c.760A>C",6508,84,6614,0.0127003326277593,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.9,15.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",12,12022678,"A","C","ETV6","ENST00000396373","missense_variant","Agc/Cgc|p.Ser262Arg/c.784A>C",5655,134,5811,0.0230597143348821,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.72,14.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066",12,12022681,"A","C","ETV6","ENST00000396373","missense_variant","Aca/Cca|p.Thr263Pro/c.787A>C",2136,25,2176,0.0114889705882353,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.87,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084",12,12022688,"T","G","ETV6","ENST00000396373","missense_variant","gTg/gGg|p.Val265Gly/c.794T>G",6328,105,6515,0.0161166538756715,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.95,14.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_095",12,12022690,"A","C","ETV6","ENST00000396373","missense_variant","Atc/Ctc|p.Ile266Leu/c.796A>C",10065,141,10237,0.0137735664745531,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.47,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",12,12022694,"A","C","ETV6","ENST00000396373","missense_variant","cAg/cCg|p.Gln267Pro/c.800A>C",5987,79,6084,0.0129848783694938,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.36,14.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084",12,12022808,"A","C","ETV6","ENST00000396373","missense_variant","aAc/aCc|p.Asn305Thr/c.914A>C",8228,120,8382,0.0143163922691482,0,0,0,0,1,0,0,0,1,"NO",0,"NO","NO","O","NO","NO","NO",8.237E-006,"NO","NO","NA","NA",26.62,14.77,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_056",12,12022826,"A","C","ETV6","ENST00000396373","missense_variant","gAc/gCc|p.Asp311Ala/c.932A>C",4863,125,5034,0.0248311481922924,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.47,14.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",12,12022874,"A","C","ETV6","ENST00000396373","missense_variant","gAg/gCg|p.Glu327Ala/c.980A>C",15775,206,16051,0.0128340913338733,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.12,14.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086",12,12022877,"A","C","ETV6","ENST00000396373","missense_variant","cAc/cCc|p.His328Pro/c.983A>C",12208,147,12425,0.011830985915493,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.12,14.95,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",12,12022898,"T","A","ETV6","ENST00000396373","missense_variant","aTa/aAa|p.Ile335Lys/c.1004T>A",15662,302,16000,0.018875,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.08,16.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_024",12,12038932,"A","T","ETV6","ENST00000396373","stop_gained","Aag/Tag|p.Lys409*/c.1225A>T",6497,73,6605,0.0110522331566995,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.55,16.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085",12,12038932,"A","T","ETV6","ENST00000396373","stop_gained","Aag/Tag|p.Lys409*/c.1225A>T",9451,131,9662,0.0135582695094183,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.22,15.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_065",12,12038946,"A","T","ETV6","ENST00000396373","missense_variant","caA/caT|p.Gln413His/c.1239A>T",8886,112,9049,0.0123770582384794,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.05,17.71,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_034",12,12043949,"A","T","ETV6","ENST00000396373","missense_variant","gAt/gTt|p.Asp443Val/c.1328A>T",3798,134,3945,0.0339670468948036,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.57,16.22,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_100",12,12043949,"A","T","ETV6","ENST00000396373","missense_variant","gAt/gTt|p.Asp443Val/c.1328A>T",9226,101,9344,0.0108090753424658,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.95,15.51,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_090",12,25380178,"G","T","KRAS","ENST00000256078","missense_variant","Cac/Aac|p.His94Asn/c.280C>A",5521,573,6105,0.0938574938574939,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.16,14.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067",12,25380230,"C","A","KRAS","ENST00000256078","missense_variant","gaG/gaT|p.Glu76Asp/c.228G>T",41272,446,41795,0.0106711329106352,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.38,14.76,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061",15,90631871,"A","C","IDH2","ENST00000330062","missense_variant","gTc/gGc|p.Val161Gly/c.482T>G",13009,241,13301,0.0181189384256823,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.82,15.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",15,90631886,"T","G","IDH2","ENST00000330062","missense_variant","aAc/aCc|p.Asn156Thr/c.467A>C",7754,83,7882,0.0105303222532352,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.51,17.7,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_004",15,90631893,"A","C","IDH2","ENST00000330062","missense_variant","Tgc/Ggc|p.Cys154Gly/c.460T>G",1387,25,1428,0.0175070028011204,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.15,15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_074",15,90631893,"A","C","IDH2","ENST00000330062","missense_variant","Tgc/Ggc|p.Cys154Gly/c.460T>G",8166,406,8695,0.0466935020126509,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.94,15.48,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",15,90631899,"T","G","IDH2","ENST00000330062","missense_variant","Atc/Ctc|p.Ile152Leu/c.454A>C",16246,227,16547,0.0137184988215386,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.67,14.25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_069",15,90631917,"T","G","IDH2","ENST00000330062","missense_variant","Act/Cct|p.Thr146Pro/c.436A>C",21879,440,22523,0.0195355858455801,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.73,14.85,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061",15,90631931,"T","G","IDH2","ENST00000330062","missense_variant","aAc/aCc|p.Asn141Thr/c.422A>C",25762,270,26204,0.0103037704167303,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.49,14.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067",15,90631941,"T","G","IDH2","ENST00000330062","missense_variant","Act/Cct|p.Thr138Pro/c.412A>C",12503,258,12835,0.0201012855473315,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.37,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",17,7574015,"A","C","TP53","ENST00000269305","missense_variant","Ttc/Gtc|p.Phe338Val/c.1012T>G",4378,84,4485,0.0187290969899666,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.95,14.68,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",17,7577048,"T","G","TP53","ENST00000269305","missense_variant","cAc/cCc|p.His297Pro/c.890A>C",15163,159,15421,0.0103106153945918,0,0,0,0,1,0,0,0,1,"NO","NO","COSM45478","cervix",1,"NO","NO","NO","NO","NO","NO","NA","NA",28.85,14.73,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",17,7577060,"C","G","TP53","ENST00000269305","missense_variant","gGg/gCg|p.Gly293Ala/c.878G>C",5097,61,5198,0.0117352828010773,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.63,14.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",17,7577569,"A","T","TP53","ENST00000269305","missense_variant","Tgt/Agt|p.Cys238Ser/c.712T>A",49823,514,50679,0.0101422680005525,0,0,0,0,1,0,0,0,1,"NO","NO","COSM43700, COSM4340287, COSM4340289, COSM4340288, COSM4340290","bone, breast, haematopoietic_and_lymphoid_tissue, liver, lung, ovary, pancreas, skin, soft_tissue","1, 1, 6, 1, 2, 2, 1, 2, 1","NO","NO","NO","NO","NO","NO","NA","NA",32.27,20.47,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",17,7577607,"A","C","TP53","ENST00000269305","missense_variant","gTt/gGt|p.Val225Gly/c.674T>G",37804,851,38933,0.0218580638532864,0,0,0,0,1,0,0,0,1,"NO","NO","COSM4770727","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",27.13,14.44,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_042",17,7578259,"A","T","TP53","ENST00000269305","missense_variant","gTg/gAg|p.Val197Glu/c.590T>A",18150,204,18444,0.011060507482108,0,0,0,0,1,0,0,0,1,"NO","NO","COSM4384929, COSM4384931, COSM44424, COSM4384930, COSM4384928","haematopoietic_and_lymphoid_tissue, skin, central_nervous_system, liver, stomach, upper_aerodigestive_tract, urinary_tract","6, 7, 1, 1, 1, 2, 1","NO","NO","NO","NO","NO","NO","NA","NA",31.13,18.99,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",17,7578427,"T","A","TP53","ENST00000269305","missense_variant","cAc/cTc|p.His168Leu/c.503A>T",6052,92,6168,0.0149156939040208,0,0,0,0,1,0,0,0,1,"NO","NO","COSM562629, COSM44801, COSM1649383, COSM562630, COSM5029896","bone, breast, large_intestine, lung, oesophagus","5, 1, 2, 1, 1","NO","NO","NO","NO","NO","NO","NA","NA",33.7,17.64,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",17,7578452,"T","A","TP53","ENST00000269305","missense_variant","Atg/Ttg|p.Met160Leu/c.478A>T",12759,135,12942,0.0104311543810848,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","rs377274728","NO","NO","NO","NO","NA","NA",33.69,19.35,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_019",17,7578469,"C","G","TP53","ENST00000269305","missense_variant","gGc/gCc|p.Gly154Ala/c.461G>C",10533,111,10671,0.0104020241776778,0,0,0,0,1,0,0,0,1,"NO","NO","COSM46378","large_intestine",1,"NO","NO","NO","NO","NO","NO","NA","NA",26.05,14.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080",17,7578469,"C","G","TP53","ENST00000269305","missense_variant","gGc/gCc|p.Gly154Ala/c.461G>C",9613,164,9805,0.0167261601223865,0,0,0,0,1,0,0,0,1,"NO","NO","COSM46378","large_intestine",1,"NO","NO","NO","NO","NO","NO","NA","NA",25.85,14.74,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",17,7578494,"A","C","TP53","ENST00000269305","missense_variant","Tgg/Ggg|p.Trp146Gly/c.436T>G",7874,124,8040,0.0154228855721393,0,0,0,0,1,0,0,0,1,"NO","NO","COSM44555","central_nervous_system",1,"NO","NO","NO","NO","NO","NO","NA","NA",27.9,15.31,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_046",17,7579398,"C","A","TP53","ENST00000269305","missense_variant","Gtc/Ttc|p.Val97Phe/c.289G>T",13384,152,13581,0.011192106619542,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.84,14.93,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_083",17,7579404,"A","T","TP53","ENST00000269305","missense_variant","Tct/Act|p.Ser95Thr/c.283T>A",1820,20,1891,0.0105764145954521,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.83,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088",17,7579407,"A","C","TP53","ENST00000269305","missense_variant","Tca/Gca|p.Ser94Ala/c.280T>G",750,45,802,0.0561097256857855,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.58,15.24,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084",17,7579409,"A","C","TP53","ENST00000269305","missense_variant","cTg/cGg|p.Leu93Arg/c.278T>G",1743,28,1820,0.0153846153846154,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.32,15.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",17,7579409,"A","T","TP53","ENST00000269305","missense_variant","cTg/cAg|p.Leu93Gln/c.278T>A",3428,63,3556,0.0177165354330709,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.68,14.49,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_001",17,7579416,"A","T","TP53","ENST00000269305","missense_variant","Tgg/Agg|p.Trp91Arg/c.271T>A",3617,74,3700,0.02,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.74,16.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_040",17,7579416,"A","T","TP53","ENST00000269305","missense_variant","Tgg/Agg|p.Trp91Arg/c.271T>A",10684,408,11208,0.0364025695931477,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.6,15.31,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_017",17,7579419,"A","T","TP53","ENST00000269305","missense_variant","Tcc/Acc|p.Ser90Thr/c.268T>A",2591,47,2669,0.0176095916073436,0,0,0,0,1,0,0,0,1,"NO","NO","COSM1735384, COSM1735386, COSM1735387, COSM1735385","pancreas",4,"NO","NO","NO","NO","NO","NO","NA","NA",28.48,15.15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063",17,7579425,"C","G","TP53","ENST00000269305","missense_variant","Gcc/Ccc|p.Ala88Pro/c.262G>C",2525,45,2577,0.0174621653084983,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.11,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_033",17,7579490,"A","T","TP53","ENST00000269305","missense_variant","aTg/aAg|p.Met66Lys/c.197T>A",2712,29,2749,0.0105492906511459,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.59,18.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",17,7579565,"T","A","TP53","ENST00000269305","missense_variant","gAt/gTt|p.Asp41Val/c.122A>T",16317,181,16570,0.0109233554616777,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.37,16.02,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_034",17,7579574,"T","A","TP53","ENST00000269305","missense_variant","cAa/cTa|p.Gln38Leu/c.113A>T",2576,31,2617,0.0118456247611769,0,0,0,0,1,0,0,0,1,"NO","NO","COSM307330","urinary_tract",1,"NO","NO","NO","NO","NO","NO","NA","NA",34.18,20.58,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_049",17,7579848,"A","T","TP53","ENST00000269305","missense_variant","cTa/cAa|p.Leu22Gln/c.65T>A",6393,113,6599,0.0171238066373693,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.09,17.61,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_096",17,7579851,"T","G","TP53","ENST00000269305","missense_variant","gAc/gCc|p.Asp21Ala/c.62A>C",3547,41,3604,0.0113762486126526,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.92,14.17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",17,7579857,"A","T","TP53","ENST00000269305","missense_variant","tTt/tAt|p.Phe19Tyr/c.56T>A",4567,78,4674,0.0166880616174583,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.45,20.01,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078",17,7579858,"A","C","TP53","ENST00000269305","missense_variant","Ttt/Gtt|p.Phe19Val/c.55T>G",3693,39,3786,0.0103011093502377,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.04,14.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064",17,7579858,"A","T","TP53","ENST00000269305","missense_variant","Ttt/Att|p.Phe19Ile/c.55T>A",1748,20,1793,0.011154489682097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.88,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_030",17,7579872,"A","C","TP53","ENST00000269305","missense_variant","cTg/cGg|p.Leu14Arg/c.41T>G",3256,34,3386,0.0100413467217956,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.47,16.35,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",17,7579872,"A","T","TP53","ENST00000269305","missense_variant","cTg/cAg|p.Leu14Gln/c.41T>A",3379,111,3561,0.0311710193765796,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.74,15.32,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",17,7579881,"T","G","TP53","ENST00000269305","missense_variant","gAg/gCg|p.Glu11Ala/c.32A>C",3501,58,3576,0.0162192393736018,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.2,14.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",17,7579893,"T","G","TP53","ENST00000269305","missense_variant","gAt/gCt|p.Asp7Ala/c.20A>C",925,32,965,0.033160621761658,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.32,14.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_041",17,74732935,"C","G","SRSF2","ENST00000392485","missense_variant","cGg/cCg|p.Arg103Pro/c.308G>C",24331,647,25022,0.025857245623851,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.81,15.04,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_081",17,74732947,"T","G","SRSF2","ENST00000392485","missense_variant","cAc/cCc|p.His99Pro/c.296A>C",1394,34,1432,0.0237430167597765,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.65,15.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_024",17,74732983,"A","C","SRSF2","ENST00000392485","missense_variant","gTg/gGg|p.Val87Gly/c.260T>G",2520,31,2565,0.0120857699805068,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.07,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",17,74732983,"A","C","SRSF2","ENST00000392485","missense_variant","gTg/gGg|p.Val87Gly/c.260T>G",179,27,207,0.130434782608696,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.91,14.48,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",17,74733004,"A","T","SRSF2","ENST00000392485","missense_variant","cTg/cAg|p.Leu80Gln/c.239T>A",3503,44,3570,0.0123249299719888,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.52,22.7,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075",17,74733160,"T","G","SRSF2","ENST00000392485","missense_variant","gAc/gCc|p.Asp28Ala/c.83A>C",2191,25,2219,0.0112663361874718,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.37,16.56,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_065",17,74733184,"T","G","SRSF2","ENST00000392485","missense_variant","aAc/aCc|p.Asn20Thr/c.59A>C",669,64,738,0.0867208672086721,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",19.09,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_106",17,74733184,"T","G","SRSF2","ENST00000392485","missense_variant","aAc/aCc|p.Asn20Thr/c.59A>C",7630,149,7799,0.0191050134632645,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",22.83,14.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108",17,74733203,"T","G","SRSF2","ENST00000392485","missense_variant","Acc/Ccc|p.Thr14Pro/c.40A>C",6603,121,6746,0.0179365549955529,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.02,14.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",19,33792299,"A","C","CEBPA","ENST00000498907","missense_variant","aTc/aGc|p.Ile341Ser/c.1022T>G",3160,104,3279,0.0317169868862458,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.24,14.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",19,33792308,"A","C","CEBPA","ENST00000498907","missense_variant","cTg/cGg|p.Leu338Arg/c.1013T>G",3615,75,3708,0.0202265372168285,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.42,14.56,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066",19,33792329,"A","C","CEBPA","ENST00000498907","missense_variant","cTg/cGg|p.Leu331Arg/c.992T>G",1544,26,1579,0.0164661177960735,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.76,15.35,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067",19,33792334,"T","G","CEBPA","ENST00000498907","missense_variant","gaA/gaC|p.Glu329Asp/c.987A>C",4762,58,4860,0.0119341563786008,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.84,15.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_003",19,33792338,"A","C","CEBPA","ENST00000498907","missense_variant","gTg/gGg|p.Val328Gly/c.983T>G",3164,34,3215,0.0105754276827372,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.87,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084",19,33792338,"A","C","CEBPA","ENST00000498907","missense_variant","gTg/gGg|p.Val328Gly/c.983T>G",7840,323,8245,0.0391752577319588,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",23.86,14.98,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071",19,33792350,"A","C","CEBPA","ENST00000498907","missense_variant","cTg/cGg|p.Leu324Arg/c.971T>G",9657,123,9853,0.0124835075611489,0,0,0,0,1,0,0,0,1,"NO","NO","COSM4170200","haematopoietic_and_lymphoid_tissue",1,"NO","NO","NO","NO","NO","NO","NA","NA",28.92,15.2,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_058",19,33792356,"T","G","CEBPA","ENST00000498907","missense_variant","gAc/gCc|p.Asp322Ala/c.965A>C",29885,374,30417,0.0122957556629516,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.47,14.64,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080",19,33792359,"T","G","CEBPA","ENST00000498907","missense_variant","aAt/aCt|p.Asn321Thr/c.962A>C",12493,225,12782,0.0176028790486622,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.24,14.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_035",19,33792364,"A","C","CEBPA","ENST00000498907","missense_variant","agT/agG|p.Ser319Arg/c.957T>G",12855,2249,15219,0.147775806557592,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.95,15.71,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",19,33792369,"T","G","CEBPA","ENST00000498907","missense_variant","Acc/Ccc|p.Thr318Pro/c.952A>C",17126,191,17423,0.0109625208058314,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.29,14.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",19,33792374,"T","G","CEBPA","ENST00000498907","missense_variant","gAg/gCg|p.Glu316Ala/c.947A>C",3603,42,3658,0.0114816839803171,0,0,0,0,1,0,0,0,1,"NO","NO","COSM1392673","large_intestine",1,"NO","NO","NO","NO","NO","NO","NA","NA",26.4,14.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_029",19,33792788,"A","C","CEBPA","ENST00000498907","missense_variant","cTc/cGc|p.Leu178Arg/c.533T>G",300,66,373,0.176943699731903,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.6,15.83,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_019",19,33793157,"A","C","CEBPA","ENST00000498907","missense_variant","aTc/aGc|p.Ile55Ser/c.164T>G",1420,55,1519,0.0362080315997367,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.91,14.13,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_029",19,33793157,"A","C","CEBPA","ENST00000498907","missense_variant","aTc/aGc|p.Ile55Ser/c.164T>G",1548,61,1673,0.0364614465032875,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.98,14.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_057",19,33793157,"A","T","CEBPA","ENST00000498907","missense_variant","aTc/aAc|p.Ile55Asn/c.164T>A",1394,105,1531,0.0685826257348138,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.84,15.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_038",19,33793158,"T","G","CEBPA","ENST00000498907","missense_variant","Atc/Ctc|p.Ile55Leu/c.163A>C",4221,182,4423,0.0411485417137689,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.78,14.39,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_029",19,33793166,"A","C","CEBPA","ENST00000498907","missense_variant","cTg/cGg|p.Leu52Arg/c.155T>G",1642,72,1752,0.0410958904109589,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",22.71,14.68,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_026",19,33793166,"A","T","CEBPA","ENST00000498907","missense_variant","cTg/cAg|p.Leu52Gln/c.155T>A",2342,69,2508,0.027511961722488,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",22.49,14.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_029",19,33793172,"T","G","CEBPA","ENST00000498907","missense_variant","gAg/gCg|p.Glu50Ala/c.149A>C",1670,81,1761,0.0459965928449744,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.2,14.09,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",19,33793179,"C","G","CEBPA","ENST00000498907","missense_variant","Gcc/Ccc|p.Ala48Pro/c.142G>C",2990,40,3040,0.0131578947368421,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.63,14.45,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",19,33793199,"T","G","CEBPA","ENST00000498907","missense_variant","cAg/cCg|p.Gln41Pro/c.122A>C",677,97,779,0.124518613607189,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",17.69,14.76,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",19,33793250,"T","G","CEBPA","ENST00000498907","missense_variant","cAc/cCc|p.His24Pro/c.71A>C",1486,24,1521,0.0157790927021696,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.58,14.92,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",19,33793345,"T","A","CEBPA","ENST00000498907","5_prime_UTR_premature_start_codon_gain_variant","|c.-25A>T",2025,37,2067,0.0179003386550556,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.68,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_030",20,31022349,"A","T","ASXL1","ENST00000375687","missense_variant","Agg/Tgg|p.Arg612Trp/c.1834A>T",5441,149,5627,0.0264794739648125,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.05,15.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_023",20,31022364,"A","T","ASXL1","ENST00000375687","missense_variant","Att/Ttt|p.Ile617Phe/c.1849A>T",5858,71,5945,0.0119428090832632,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.75,16.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_039",20,31022369,"A","T","ASXL1","ENST00000375687","missense_variant","aaA/aaT|p.Lys618Asn/c.1854A>T",4449,58,4598,0.0126141800782949,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.6,14.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",20,31022383,"A","T","ASXL1","ENST00000375687","missense_variant","cAg/cTg|p.Gln623Leu/c.1868A>T",3941,120,4091,0.0293326814959668,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.76,15.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_002",20,31022397,"A","T","ASXL1","ENST00000375687","stop_gained","Aga/Tga|p.Arg628*/c.1882A>T",1356,29,1389,0.0208783297336213,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.31,15.21,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_026",20,31022399,"A","T","ASXL1","ENST00000375687","missense_variant","agA/agT|p.Arg628Ser/c.1884A>T",5705,91,5827,0.0156169555517419,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.97,14.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_027",20,31022409,"T","A","ASXL1","ENST00000375687","missense_variant","Tgc/Agc|p.Cys632Ser/c.1894T>A",5880,69,6038,0.0114276250414044,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.95,15.16,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071",20,31022409,"T","G","ASXL1","ENST00000375687","missense_variant","Tgc/Ggc|p.Cys632Gly/c.1894T>G",1607,46,1670,0.0275449101796407,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.14,15.54,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",20,31022478,"A","C","ASXL1","ENST00000375687","missense_variant","Acc/Ccc|p.Thr655Pro/c.1963A>C",2365,36,2417,0.0148944973107158,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.61,18.78,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",20,31022524,"A","C","ASXL1","ENST00000375687","missense_variant","gAg/gCg|p.Glu670Ala/c.2009A>C",4149,91,4281,0.021256715720626,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.64,14.96,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_100",20,31022536,"A","C","ASXL1","ENST00000375687","missense_variant","cAc/cCc|p.His674Pro/c.2021A>C",11989,146,12177,0.0119898168678656,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.48,14.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078",20,31022559,"A","C","ASXL1","ENST00000375687","missense_variant","Agc/Cgc|p.Ser682Arg/c.2044A>C",5344,180,5547,0.0324499729583559,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.14,14.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_046",20,31022562,"A","C","ASXL1","ENST00000375687","missense_variant","Acc/Ccc|p.Thr683Pro/c.2047A>C",23270,591,24026,0.0245983517855656,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.39,18.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088",20,31022562,"A","C","ASXL1","ENST00000375687","missense_variant","Acc/Ccc|p.Thr683Pro/c.2047A>C",3638,217,3867,0.0561158520817171,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.02,17.25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_019",20,31022973,"G","T","ASXL1","ENST00000375687","missense_variant","Gat/Tat|p.Asp820Tyr/c.2458G>T",18841,878,19751,0.0444534453951699,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.98,14.18,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_101",20,31022973,"G","T","ASXL1","ENST00000375687","missense_variant","Gat/Tat|p.Asp820Tyr/c.2458G>T",17036,1633,18709,0.0872841947725694,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,14.92,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",20,31023022,"C","T","ASXL1","ENST00000375687","missense_variant","aCt/aTt|p.Thr836Ile/c.2507C>T",46476,861,47601,0.0180878552971576,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.13,15.55,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_105",20,31023022,"C","T","ASXL1","ENST00000375687","missense_variant","aCt/aTt|p.Thr836Ile/c.2507C>T",20548,807,21465,0.0375960866526904,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.03,15.51,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061",20,31023026,"G","T","ASXL1","ENST00000375687","missense_variant","atG/atT|p.Met837Ile/c.2511G>T",20649,383,21373,0.0179198053619052,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.83,14.59,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_026",20,31023027,"A","T","ASXL1","ENST00000375687","stop_gained","Aag/Tag|p.Lys838*/c.2512A>T",30255,435,30915,0.0140708393983503,0,0,0,0,1,0,0,0,1,"NO","NO","COSM145115","haematopoietic_and_lymphoid_tissue",3,"NO","NO","NO","NO","NO","NO","NA","NA",33.66,15.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071",20,31023027,"A","T","ASXL1","ENST00000375687","stop_gained","Aag/Tag|p.Lys838*/c.2512A>T",15807,168,16073,0.0104523113295589,0,0,0,0,1,0,0,0,1,"NO","NO","COSM145115","haematopoietic_and_lymphoid_tissue",3,"NO","NO","NO","NO","NO","NO","NA","NA",32.59,17.49,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_005",20,31023028,"A","T","ASXL1","ENST00000375687","missense_variant","aAg/aTg|p.Lys838Met/c.2513A>T",6923,107,7060,0.0151558073654391,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.5,14.2,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068",20,31023028,"A","T","ASXL1","ENST00000375687","missense_variant","aAg/aTg|p.Lys838Met/c.2513A>T",14956,152,15187,0.010008559952591,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.13,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_037",20,31023029,"G","T","ASXL1","ENST00000375687","missense_variant","aaG/aaT|p.Lys838Asn/c.2514G>T",42609,769,43439,0.0177029857961739,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",3.295E-005,"NO","NO","NA","NA",33.72,14.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_103",20,31023029,"G","T","ASXL1","ENST00000375687","missense_variant","aaG/aaT|p.Lys838Asn/c.2514G>T",17543,493,18081,0.0272661910292572,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",3.295E-005,"NO","NO","NA","NA",33.28,14.84,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_010",20,31023030,"G","T","ASXL1","ENST00000375687","missense_variant","Gat/Tat|p.Asp839Tyr/c.2515G>T",35414,709,36180,0.0195964621337756,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.46,14.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_003",20,31023031,"A","T","ASXL1","ENST00000375687","missense_variant","gAt/gTt|p.Asp839Val/c.2516A>T",4033,51,4089,0.012472487160675,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.54,14.78,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_031",20,31023033,"C","A","ASXL1","ENST00000375687","missense_variant","Cct/Act|p.Pro840Thr/c.2518C>A",18097,400,18612,0.021491510853213,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.78,18.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080",20,31023033,"C","A","ASXL1","ENST00000375687","missense_variant","Cct/Act|p.Pro840Thr/c.2518C>A",19575,469,20147,0.0232789000843798,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",31.18,17.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_045",20,31023034,"C","T","ASXL1","ENST00000375687","missense_variant","cCt/cTt|p.Pro840Leu/c.2519C>T",38820,895,40184,0.0222725462870794,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.18,18.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_033",20,31023036,"G","T","ASXL1","ENST00000375687","missense_variant","Gta/Tta|p.Val841Leu/c.2521G>T",21174,947,22171,0.0427134545126517,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.58,25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085",20,31023036,"G","T","ASXL1","ENST00000375687","missense_variant","Gta/Tta|p.Val841Leu/c.2521G>T",15343,633,16042,0.0394589203341229,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.46,21.34,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",20,31023040,"A","T","ASXL1","ENST00000375687","missense_variant","aAt/aTt|p.Asn842Ile/c.2525A>T",35928,1883,37996,0.0495578481945468,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",33.25,23.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_097",20,31023040,"A","T","ASXL1","ENST00000375687","missense_variant","aAt/aTt|p.Asn842Ile/c.2525A>T",23885,1238,25197,0.0491328332738024,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.05,24.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",20,31023321,"A","C","ASXL1","ENST00000375687","missense_variant","Acc/Ccc|p.Thr936Pro/c.2806A>C",11805,263,12117,0.0217050425022695,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.79,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076",20,31023348,"A","C","ASXL1","ENST00000375687","missense_variant","Aca/Cca|p.Thr945Pro/c.2833A>C",16868,516,17513,0.0294638268714669,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.92,14.58,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066",20,31023573,"G","T","ASXL1","ENST00000375687","stop_gained","Gaa/Taa|p.Glu1020*/c.3058G>T",37819,537,38399,0.0139847391859163,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.89,14.64,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_025",20,31023712,"T","G","ASXL1","ENST00000375687","missense_variant","gTg/gGg|p.Val1066Gly/c.3197T>G",34474,5615,40303,0.1393196536238,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.54,17.54,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",20,31023712,"T","G","ASXL1","ENST00000375687","missense_variant","gTg/gGg|p.Val1066Gly/c.3197T>G",34040,3147,37510,0.0838976272993868,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.17,16.89,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_104",20,31023712,"T","G","ASXL1","ENST00000375687","missense_variant","gTg/gGg|p.Val1066Gly/c.3197T>G",26535,3668,30380,0.12073732718894,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.54,18.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",20,31023730,"T","G","ASXL1","ENST00000375687","missense_variant","gTc/gGc|p.Val1072Gly/c.3215T>G",14388,660,15128,0.0436277102062401,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.31,14.92,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",20,31023937,"A","C","ASXL1","ENST00000375687","missense_variant","gAc/gCc|p.Asp1141Ala/c.3422A>C",29627,623,30407,0.020488703259118,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO","NA","NA",29.4,14.7,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_093",20,31024030,"C","G","ASXL1","ENST00000375687","missense_variant","gCt/gGt|p.Ala1172Gly/c.3515C>G",14999,153,15194,0.0100697643806766,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.66,14.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062",20,31024095,"A","C","ASXL1","ENST00000375687","missense_variant","Acc/Ccc|p.Thr1194Pro/c.3580A>C",21919,342,22393,0.015272629839682,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.56,14.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_058",20,31024518,"A","C","ASXL1","ENST00000375687","missense_variant","Agt/Cgt|p.Ser1335Arg/c.4003A>C",17901,199,18534,0.010737023848063,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.22,15.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_028",20,31024518,"A","T","ASXL1","ENST00000375687","missense_variant","Agt/Tgt|p.Ser1335Cys/c.4003A>T",11024,136,11330,0.0120035304501324,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.14,17.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086",20,31024518,"A","T","ASXL1","ENST00000375687","missense_variant","Agt/Tgt|p.Ser1335Cys/c.4003A>T",12939,254,13415,0.0189340290719344,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.46,16.08,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_042",20,31024702,"T","A","ASXL1","ENST00000375687","missense_variant","gTg/gAg|p.Val1396Glu/c.4187T>A",10849,117,11016,0.0106209150326797,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.75,18.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",20,31024729,"T","G","ASXL1","ENST00000375687","missense_variant","gTc/gGc|p.Val1405Gly/c.4214T>G",5585,60,5677,0.0105689624801832,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.34,14.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_032",21,36164432,"T","G","RUNX1","ENST00000437180","stop_lost","tgA/tgC|p.Ter481Cysext*?/c.1443A>C",2105,47,2165,0.0217090069284065,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.16,14.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",21,36164446,"A","C","RUNX1","ENST00000437180","missense_variant","Tgg/Ggg|p.Trp477Gly/c.1429T>G",6133,133,6313,0.0210676382068747,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.15,15.09,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_048",21,36164448,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val476Gly/c.1427T>G",14105,328,14595,0.0224734498115793,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.64,14.85,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_043",21,36164460,"A","C","RUNX1","ENST00000437180","missense_variant","cTg/cGg|p.Leu472Arg/c.1415T>G",8692,133,8906,0.0149337525263867,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.13,14.71,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_036",21,36164478,"A","C","RUNX1","ENST00000437180","missense_variant","aTg/aGg|p.Met466Arg/c.1397T>G",7109,74,7222,0.0102464691221268,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.89,14.39,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",21,36164479,"T","G","RUNX1","ENST00000437180","missense_variant","Atg/Ctg|p.Met466Leu/c.1396A>C",6145,133,6317,0.0210542979262308,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27,15.23,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",21,36164481,"T","G","RUNX1","ENST00000437180","missense_variant","aAc/aCc|p.Asn465Thr/c.1394A>C",10510,407,10977,0.037077525735629,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.08,14.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_045",21,36164485,"T","G","RUNX1","ENST00000437180","missense_variant","Acc/Ccc|p.Thr464Pro/c.1390A>C",12774,286,13140,0.021765601217656,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.08,17.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_026",21,36164491,"A","G","RUNX1","ENST00000437180","missense_variant","Tcc/Ccc|p.Ser462Pro/c.1384T>C",2740,64,2835,0.0225749559082892,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.79,21.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_095",21,36164605,"A","C","RUNX1","ENST00000437180","missense_variant","Tcg/Gcg|p.Ser424Ala/c.1270T>G",692,423,1186,0.356661045531197,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",15.17,14.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_051",21,36164605,"A","G","RUNX1","ENST00000437180","missense_variant","Tcg/Ccg|p.Ser424Pro/c.1270T>C",886,790,2252,0.350799289520426,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",19.43,14.31,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",21,36164608,"G","C","RUNX1","ENST00000437180","missense_variant","Cgc/Ggc|p.Arg423Gly/c.1267C>G",1752,26,1784,0.0145739910313901,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",22.39,15.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_030",21,36164610,"T","A","RUNX1","ENST00000437180","missense_variant","gAg/gTg|p.Glu422Val/c.1265A>T",687,262,2131,0.122946973251994,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",17.56,14.45,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_035",21,36164610,"T","G","RUNX1","ENST00000437180","missense_variant","gAg/gCg|p.Glu422Ala/c.1265A>C",762,1271,2357,0.539244802715316,1,0,0,0,1,0,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",17.52,14.02,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_020",21,36164611,"C","A","RUNX1","ENST00000437180","stop_gained","Gag/Tag|p.Glu422*/c.1264G>T",846,26,872,0.0298165137614679,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",21.58,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_040",21,36164622,"A","C","RUNX1","ENST00000437180","missense_variant","aTg/aGg|p.Met418Arg/c.1253T>G",1020,523,1548,0.337855297157623,0,0,0,0,0,0,1,0,1,"NO",0.001,"NO","NO","O","NO","rs202068364","NO",9.877E-005,"NO","NO","NA","NA",17.38,14.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",21,36164623,"T","A","RUNX1","ENST00000437180","missense_variant","Atg/Ttg|p.Met418Leu/c.1252A>T",2956,670,3805,0.176084099868594,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.06,14.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_101",21,36164623,"T","G","RUNX1","ENST00000437180","missense_variant","Atg/Ctg|p.Met418Leu/c.1252A>C",1508,81,1887,0.0429252782193959,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.68,14.09,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_097",21,36164626,"A","G","RUNX1","ENST00000437180","missense_variant","Tcc/Ccc|p.Ser417Pro/c.1249T>C",3480,45,3553,0.0126653532226288,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.66,16.18,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_016",21,36164628,"A","G","RUNX1","ENST00000437180","missense_variant","tTc/tCc|p.Phe416Ser/c.1247T>C",2485,73,2581,0.028283611003487,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.88,14.79,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_096",21,36164628,"A","G","RUNX1","ENST00000437180","missense_variant","tTc/tCc|p.Phe416Ser/c.1247T>C",2902,47,3085,0.0152350081037277,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.26,16.91,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",21,36164630,"C","A","RUNX1","ENST00000437180","missense_variant","caG/caT|p.Gln415His/c.1245G>T",3306,41,3365,0.012184249628529,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.91,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007",21,36164631,"T","A","RUNX1","ENST00000437180","missense_variant","cAg/cTg|p.Gln415Leu/c.1244A>T",2866,511,3642,0.140307523338825,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.85,14.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_103",21,36164631,"T","G","RUNX1","ENST00000437180","missense_variant","cAg/cCg|p.Gln415Pro/c.1244A>C",2118,251,2629,0.095473564092811,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.12,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_009",21,36164634,"T","G","RUNX1","ENST00000437180","missense_variant","tAc/tCc|p.Tyr414Ser/c.1241A>C",3394,574,3988,0.143931795386158,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.44,14.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_031",21,36164635,"A","T","RUNX1","ENST00000437180","missense_variant","Tac/Aac|p.Tyr414Asn/c.1240T>A",3424,113,3554,0.0317951603826674,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.24,14.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_094",21,36164638,"A","C","RUNX1","ENST00000437180","missense_variant","Tcc/Gcc|p.Ser413Ala/c.1237T>G",2327,62,2482,0.0249798549556809,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.65,14.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_054",21,36164638,"A","G","RUNX1","ENST00000437180","missense_variant","Tcc/Ccc|p.Ser413Pro/c.1237T>C",3139,144,3323,0.0433343364429732,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.3,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_014",21,36164646,"G","C","RUNX1","ENST00000437180","missense_variant","tCg/tGg|p.Ser410Trp/c.1229C>G",3389,99,3497,0.0283099799828424,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.85,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050",21,36164646,"G","C","RUNX1","ENST00000437180","missense_variant","tCg/tGg|p.Ser410Trp/c.1229C>G",3686,67,3760,0.0178191489361702,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.66,14.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_030",21,36164647,"A","C","RUNX1","ENST00000437180","missense_variant","Tcg/Gcg|p.Ser410Ala/c.1228T>G",4076,645,4776,0.135050251256281,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.24,14.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_103",21,36164647,"A","C","RUNX1","ENST00000437180","missense_variant","Tcg/Gcg|p.Ser410Ala/c.1228T>G",2151,427,2598,0.164357197844496,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.48,14.34,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_025",21,36164654,"G","C","RUNX1","ENST00000437180","stop_gained","taC/taG|p.Tyr407*/c.1221C>G",5014,234,5260,0.0444866920152091,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.7,14.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_107",21,36164654,"G","C","RUNX1","ENST00000437180","stop_gained","taC/taG|p.Tyr407*/c.1221C>G",4507,130,4640,0.0280172413793103,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.1,14.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",21,36164655,"T","G","RUNX1","ENST00000437180","missense_variant","tAc/tCc|p.Tyr407Ser/c.1220A>C",4946,894,5897,0.151602509750721,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",34.2,15.25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_089",21,36164658,"T","G","RUNX1","ENST00000437180","missense_variant","tAc/tCc|p.Tyr406Ser/c.1217A>C",1777,153,1939,0.0789066529138731,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.36,14.08,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_028",21,36164659,"A","T","RUNX1","ENST00000437180","missense_variant","Tac/Aac|p.Tyr406Asn/c.1216T>A",2624,79,2720,0.0290441176470588,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.43,14.94,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_103",21,36164662,"G","C","RUNX1","ENST00000437180","missense_variant","Ctg/Gtg|p.Leu405Val/c.1213C>G",2461,36,2506,0.014365522745411,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.35,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_055",21,36164664,"T","G","RUNX1","ENST00000437180","missense_variant","cAc/cCc|p.His404Pro/c.1211A>C",5383,381,5847,0.0651616213442791,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.08,14.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_028",21,36164667,"T","G","RUNX1","ENST00000437180","missense_variant","tAc/tCc|p.Tyr403Ser/c.1208A>C",2249,391,2644,0.147881996974281,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.37,14.81,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_106",21,36164667,"T","G","RUNX1","ENST00000437180","missense_variant","tAc/tCc|p.Tyr403Ser/c.1208A>C",3763,901,4669,0.192974941100878,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.62,14.58,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_013",21,36164668,"A","T","RUNX1","ENST00000437180","missense_variant","Tac/Aac|p.Tyr403Asn/c.1207T>A",725,21,749,0.0280373831775701,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.25,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_052",21,36164671,"A","G","RUNX1","ENST00000437180","missense_variant","Tcc/Ccc|p.Ser402Pro/c.1204T>C",3705,82,3841,0.021348607133559,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.46,17.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_015",21,36164677,"A","G","RUNX1","ENST00000437180","missense_variant","Tcg/Ccg|p.Ser400Pro/c.1198T>C",4115,49,4187,0.0117028898973012,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.47,15.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_040",21,36164680,"T","G","RUNX1","ENST00000437180","missense_variant","Agc/Cgc|p.Ser399Arg/c.1195A>C",2430,26,2471,0.0105220558478349,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.81,14.27,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_044",21,36164835,"A","T","RUNX1","ENST00000437180","missense_variant","aTg/aAg|p.Met347Lys/c.1040T>A",3759,45,3806,0.011823436678928,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.92,17.02,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_081",21,36164850,"A","C","RUNX1","ENST00000437180","missense_variant","aTc/aGc|p.Ile342Ser/c.1025T>G",7919,134,8090,0.0165636588380717,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.16,15.31,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_081",21,36164868,"A","C","RUNX1","ENST00000437180","missense_variant","tTc/tGc|p.Phe336Cys/c.1007T>G",7708,224,7971,0.028101869276126,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.45,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_044",21,36164869,"A","T","RUNX1","ENST00000437180","missense_variant","Ttc/Atc|p.Phe336Ile/c.1006T>A",3734,42,3809,0.0110265161459701,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO",8.298E-006,"NO","NO","NA","NA",26.73,16,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_008",21,36171706,"A","T","RUNX1","ENST00000437180","missense_variant","Tac/Aac|p.Tyr287Asn/c.859T>A",44138,501,44721,0.011202790635272,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",32.96,16.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_003",21,36206758,"A","C","RUNX1","ENST00000437180","missense_variant","Tcc/Gcc|p.Ser252Ala/c.754T>G",398,24,439,0.0546697038724374,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.56,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_005",21,36206758,"A","T","RUNX1","ENST00000437180","missense_variant","Tcc/Acc|p.Ser252Thr/c.754T>A",696,38,773,0.0491591203104787,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",29.33,14.34,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_056",21,36206758,"A","T","RUNX1","ENST00000437180","missense_variant","Tcc/Acc|p.Ser252Thr/c.754T>A",2864,120,3126,0.0383877159309021,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.92,14.41,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_006",21,36206763,"C","G","RUNX1","ENST00000437180","missense_variant","cGt/cCt|p.Arg250Pro/c.749G>C",1556,41,1597,0.0256731371321227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",28.62,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_095",21,36206763,"C","G","RUNX1","ENST00000437180","missense_variant","cGt/cCt|p.Arg250Pro/c.749G>C",4000,220,4222,0.0521080056845097,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.87,14.16,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_059",21,36206769,"T","G","RUNX1","ENST00000437180","missense_variant","aAc/aCc|p.Asn248Thr/c.743A>C",1429,89,1525,0.0583606557377049,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",1.647E-005,"NO","NO","NA","NA",25.46,14.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_003",21,36206770,"T","G","RUNX1","ENST00000437180","missense_variant","Aac/Cac|p.Asn248His/c.742A>C",420,51,473,0.107822410147992,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.5,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063",21,36206770,"T","G","RUNX1","ENST00000437180","missense_variant","Aac/Cac|p.Asn248His/c.742A>C",2711,445,3161,0.140778234735843,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.74,15.83,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_041",21,36206776,"T","G","RUNX1","ENST00000437180","missense_variant","Acg/Ccg|p.Thr246Pro/c.736A>C",5413,1596,7057,0.2261584242596,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.64,15.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",21,36206776,"T","G","RUNX1","ENST00000437180","missense_variant","Acg/Ccg|p.Thr246Pro/c.736A>C",1457,332,1798,0.184649610678532,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.32,15.82,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_024",21,36206782,"C","G","RUNX1","ENST00000437180","missense_variant","Gcc/Ccc|p.Ala244Pro/c.730G>C",2164,41,2222,0.0184518451845185,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.25,14.32,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080",21,36206782,"C","G","RUNX1","ENST00000437180","missense_variant","Gcc/Ccc|p.Ala244Pro/c.730G>C",5683,148,5858,0.0252645954250597,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.91,14.74,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_031",21,36206787,"T","G","RUNX1","ENST00000437180","missense_variant","cAc/cCc|p.His242Pro/c.725A>C",3272,360,3643,0.0988196541312105,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.96,14.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079",21,36206787,"T","G","RUNX1","ENST00000437180","missense_variant","cAc/cCc|p.His242Pro/c.725A>C",1739,153,1905,0.0803149606299213,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.03,14.85,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_047",21,36206790,"T","G","RUNX1","ENST00000437180","missense_variant","cAc/cCc|p.His241Pro/c.722A>C",10275,879,11223,0.078321304464047,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.8,14.64,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_058",21,36206799,"A","C","RUNX1","ENST00000437180","missense_variant","gTc/gGc|p.Val238Gly/c.713T>G",5297,97,5457,0.0177753344328386,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",27.72,15.15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063",21,36206801,"C","G","RUNX1","ENST00000437180","missense_variant","agG/agC|p.Arg237Ser/c.711G>C",3262,42,3310,0.0126888217522659,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.59,15.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082",21,36206820,"A","C","RUNX1","ENST00000437180","missense_variant","cTg/cGg|p.Leu231Arg/c.692T>G",2296,36,2352,0.0153061224489796,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.68,15.11,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_091",21,36206825,"C","G","RUNX1","ENST00000437180","missense_variant","gaG/gaC|p.Glu229Asp/c.687G>C",2903,31,2958,0.0104800540906018,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",26.42,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011",21,36206829,"A","T","RUNX1","ENST00000437180","missense_variant","cTg/cAg|p.Leu228Gln/c.683T>A",2410,31,2448,0.0126633986928105,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.14,16.77,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_072",21,36231827,"A","C","RUNX1","ENST00000437180","missense_variant","gTc/gGc|p.Val186Gly/c.557T>G",8933,302,9272,0.0325711820534944,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.96,15.01,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_017",21,36231843,"T","G","RUNX1","ENST00000437180","missense_variant","Aca/Cca|p.Thr181Pro/c.541A>C",6849,519,7403,0.0701067134945292,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",25.92,15.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061",21,36231843,"T","G","RUNX1","ENST00000437180","missense_variant","Aca/Cca|p.Thr181Pro/c.541A>C",16550,1848,18491,0.099940511600238,0,0,0,0,1,1,0,0,2,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",26.5,18.89,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",21,36231848,"A","C","RUNX1","ENST00000437180","missense_variant","gTc/gGc|p.Val179Gly/c.536T>G",16638,173,16933,0.0102167365499321,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.86,15.31,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061",21,36231864,"T","G","RUNX1","ENST00000437180","missense_variant","Act/Cct|p.Thr174Pro/c.520A>C",18438,261,18785,0.0138940644130956,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.25,14.87,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_059",21,36252900,"C","G","RUNX1","ENST00000437180","missense_variant","caG/caC|p.Gln154His/c.462G>C",3163,41,3218,0.0127408328154133,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO",8.236E-006,"NO","NO","NA","NA",30.64,14.17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_096",21,36259213,"T","G","RUNX1","ENST00000437180","missense_variant","gAc/gCc|p.Asp93Ala/c.278A>C",5356,2641,8024,0.329137587238285,0,1,0,0,1,1,0,0,3,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",30.71,22.98,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071",21,36259222,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val90Gly/c.269T>G",1658,50,1716,0.0291375291375291,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NA","NA","NO","NO","NO","NO","NO","NO","NA","NA",24.62,14.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_090",21,36259240,"T","G","RUNX1","ENST00000437180","missense_variant","gAc/gCc|p.Asp84Ala/c.251A>C",9935,149,10119,0.0147247751754126,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,14.61,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_105",21,36259255,"A","C","RUNX1","ENST00000437180","missense_variant","gTg/gGg|p.Val79Gly/c.236T>G",6473,86,6572,0.0130858186244674,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.84,14.45,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073",21,44524449,"C","A","U2AF1","ENST00000291552","missense_variant","ttG/ttT|p.Leu36Phe/c.108G>T",7404,78,7494,0.0104083266613291,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.94,14.73,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070",21,44524459,"C","A","U2AF1","ENST00000291552","missense_variant","tGc/tTc|p.Cys33Phe/c.98G>T",14437,152,14621,0.0103960057451611,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.33,14.99,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_010",21,44524505,"A","T","U2AF1","ENST00000291552","missense_variant","Tgt/Agt|p.Cys18Ser/c.52T>A",17188,186,17431,0.0106706442544891,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",33.56,16.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_011","X",15809131,"A","T","ZRSR2","ENST00000307771","missense_variant","gAc/gTc|p.Asp39Val/c.116A>T",2541,26,2578,0.0100853374709077,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.13,16.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_006","X",15818036,"G","T","ZRSR2","ENST00000307771","stop_gained","Gaa/Taa|p.Glu55*/c.163G>T",293,40,336,0.119047619047619,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.72,14.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076","X",15827348,"A","C","ZRSR2","ENST00000307771","missense_variant","aAc/aCc|p.Asn155Thr/c.464A>C",2232,36,2273,0.0158380994280686,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.91,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_007","X",15827409,"C","A","ZRSR2","ENST00000307771","stop_gained","taC/taA|p.Tyr175*/c.525C>A",19156,546,19735,0.02766658221434,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.53,15.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_109","X",15827409,"C","A","ZRSR2","ENST00000307771","stop_gained","taC/taA|p.Tyr175*/c.525C>A",9941,273,10241,0.0266575529733424,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.4,14.92,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_008","X",15840946,"A","T","ZRSR2","ENST00000307771","stop_gained","Aga/Tga|p.Arg344*/c.1030A>T",28350,418,28821,0.0145033135560876,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.35,15.99,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_053","X",15841002,"A","T","ZRSR2","ENST00000307771","missense_variant","gaA/gaT|p.Glu362Asp/c.1086A>T",15081,179,15337,0.0116711221229706,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.87,16.99,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085","X",15841134,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys406Asn/c.1218A>C",1409,26,1443,0.018018018018018,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",23.34,14.85,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079","X",15841142,"A","C","ZRSR2","ENST00000307771","missense_variant","aAa/aCa|p.Lys409Thr/c.1226A>C",1062,39,1110,0.0351351351351351,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",21.96,14.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061","X",15841156,"A","C","ZRSR2","ENST00000307771","missense_variant","Agt/Cgt|p.Ser414Arg/c.1240A>C",1804,24,1831,0.0131075914800655,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.02,14.83,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050","X",15841158,"T","A","ZRSR2","ENST00000307771","missense_variant","agT/agA|p.Ser414Arg/c.1242T>A",1461,23,1501,0.0153231179213857,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.23,14.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062","X",15841172,"A","C","ZRSR2","ENST00000307771","missense_variant","aAt/aCt|p.Asn419Thr/c.1256A>C",1626,21,1659,0.0126582278481013,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",25.46,14.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062","X",15841173,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn419Lys/c.1257T>A",1573,22,1661,0.0132450331125828,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.04,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085","X",15841173,"T","G","ZRSR2","ENST00000307771","missense_variant","aaT/aaG|p.Asn419Lys/c.1257T>G",2746,87,2880,0.0302083333333333,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.22,14.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075","X",15841185,"A","C","ZRSR2","ENST00000307771","missense_variant","agA/agC|p.Arg423Ser/c.1269A>C",2274,37,2327,0.0159003008165019,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.15,14.68,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_059","X",15841193,"A","C","ZRSR2","ENST00000307771","missense_variant","aAt/aCt|p.Asn426Thr/c.1277A>C",5100,75,5232,0.0143348623853211,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",24.91,14.63,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_032","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2267,48,2318,0.0207075064710958,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.2,15.08,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_012","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2004,29,2035,0.0142506142506142,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.12,14.45,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_060","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1559,36,1608,0.0223880597014925,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.01,14.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_040","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",7070,173,7260,0.0238292011019284,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.16,17.5,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_013","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1037,27,1066,0.025328330206379,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",30.51,17.52,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_093","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3002,33,3041,0.0108516935218678,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.54,16.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3465,103,3581,0.0287629153867635,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.12,15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1575,46,1628,0.0282555282555283,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.03,17.09,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1779,56,1853,0.0302212628170534,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.47,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_064","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",6894,200,7131,0.0280465572850933,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,15.62,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_065","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",6377,218,6626,0.0329006942348325,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.02,15.43,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3073,102,3192,0.0319548872180451,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.02,14.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",4131,136,4294,0.031672100605496,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,14.79,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",4311,120,4463,0.026887743670177,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.1,15.37,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_069","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2457,71,2553,0.0278104191147669,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.15,15.42,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2890,93,3003,0.030969030969031,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.46,16.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1310,38,1359,0.0279617365710081,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.27,17,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_072","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2108,68,2192,0.031021897810219,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.68,15.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_073","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2332,63,2410,0.0261410788381743,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,15.51,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_074","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3117,90,3234,0.0278293135435993,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29,14.94,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2207,70,2293,0.0305276929786306,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.39,15.13,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2166,75,2256,0.0332446808510638,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.8,15.24,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_077","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2255,61,2329,0.0261914984972091,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,15.84,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1941,56,2007,0.0279023418036871,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.08,15.14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2066,65,2145,0.0303030303030303,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.05,15.32,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1521,42,1569,0.0267686424474187,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.31,15.26,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_081","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",4330,134,4494,0.0298175344904317,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.98,14.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",5816,173,6019,0.0287423159993354,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,16.15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_083","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2266,50,2331,0.0214500214500215,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.9,14.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3146,94,3261,0.0288255136461208,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,15.56,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2695,87,2802,0.0310492505353319,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.05,15.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",4663,138,4837,0.0285300806284887,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.97,15.4,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2876,98,3004,0.0326231691078562,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.89,15.87,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",4740,157,4925,0.0318781725888325,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.06,15.01,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_095","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3934,49,3995,0.0122653316645807,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.32,14.65,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_096","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3042,40,3092,0.0129366106080207,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.43,15.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_097","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3446,37,3489,0.0106047578102608,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.54,14.49,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_100","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3865,42,3914,0.0107307102708227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.3,17.12,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_101","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1952,25,1981,0.0126198889449773,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.47,15.72,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_102","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",1793,26,1824,0.0142543859649123,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.36,14,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_106","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",2880,34,2927,0.0116159890673044,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.44,15,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_107","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",3033,35,3081,0.0113599480688088,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.22,14.71,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_108","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",6766,82,6862,0.0119498688429029,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.46,14.9,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_111","X",15841194,"T","A","ZRSR2","ENST00000307771","missense_variant","aaT/aaA|p.Asn426Lys/c.1278T>A",5623,65,5707,0.0113895216400911,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",31.35,16.6,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_006","X",15841205,"G","T","ZRSR2","ENST00000307771","missense_variant","aGc/aTc|p.Ser430Ile/c.1289G>T",2582,28,2614,0.0107115531752104,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",34.33,23.39,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_060","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",4310,49,4385,0.0111744583808438,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,15.18,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",11870,175,12103,0.0144592249855408,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.9,15.25,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_062","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",5729,101,5850,0.0172649572649573,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.93,14.92,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_063","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",5479,73,5572,0.0131012203876525,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.29,15.29,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_065","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",2715,44,2770,0.015884476534296,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.39,15.59,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_066","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",7662,102,7796,0.013083632632119,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.55,15.67,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_067","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",9967,122,10122,0.0120529539616677,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.87,14.75,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_068","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",14349,236,14644,0.016115815350997,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.95,14.93,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_069","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6720,104,6848,0.0151869158878505,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.19,14.98,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_070","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",8961,145,9139,0.0158660684976474,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.75,15.99,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_071","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",3282,50,3340,0.0149700598802395,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.2,15.52,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_072","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",2195,23,2228,0.0103231597845601,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.89,14.3,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_074","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6546,92,6657,0.0138200390566321,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.5,15.46,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_075","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",5519,85,5624,0.0151137980085349,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.75,14.4,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_076","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",5530,101,5661,0.0178413707825473,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.91,15.66,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_077","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6723,94,6842,0.01373867290266,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.06,14.91,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_078","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",5587,86,5691,0.0151115796872254,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.55,14.57,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_079","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6080,81,6183,0.0131004366812227,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.26,15.77,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_080","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",2447,35,2494,0.0140336808340016,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.15,14.97,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_082","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",11300,143,11482,0.0124542762584916,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.66,15.04,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_083","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6654,75,6766,0.011084835944428,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.88,15.69,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_084","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",8135,135,8299,0.0162670201229064,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.84,15.05,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_085","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",7902,108,8044,0.0134261561412233,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.01,15.38,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_086","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",11610,170,11835,0.0143641740599916,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.8,15.19,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_087","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",6558,123,6697,0.0183664327310736,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.27,15.8,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088","X",15841334,"A","C","ZRSR2","ENST00000307771","missense_variant","gAc/gCc|p.Asp473Ala/c.1418A>C",11359,127,11521,0.0110233486676504,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.93,15.36,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_060","X",15841338,"A","C","ZRSR2","ENST00000307771","missense_variant","agA/agC|p.Arg474Ser/c.1422A>C",4287,81,4385,0.0184720638540479,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",29.46,15.72,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_061","X",15841338,"A","C","ZRSR2","ENST00000307771","missense_variant","agA/agC|p.Arg474Ser/c.1422A>C",11773,255,12099,0.0210761219935532,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",28.98,15.2,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
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["UPN_Tr2_087","X",15841356,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys480Asn/c.1440A>C",13066,157,13268,0.0118329816098885,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.4,15.54,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_088","X",15841356,"A","C","ZRSR2","ENST00000307771","missense_variant","aaA/aaC|p.Lys480Asn/c.1440A>C",22474,231,22798,0.0101324677603299,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",27.94,14.32,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
["UPN_Tr2_050","X",15841361,"A","T","ZRSR2","ENST00000307771","missense_variant","aAa/aTa|p.Lys482Ile/c.1445A>T",4456,48,4527,0.0106030483764082,0,0,0,0,1,0,0,0,1,"NO","NO","NO","NO","O","NO","NO","NO","NO","NO","NO","NA","NA",32.62,24.48,"NA","NA","NA","NA","NA","NA","NA","NA","low bq","NA"]
[{"$nulls":13},{"$f":"SUM(N2:N32061)","v":57},{"$f":"SUM(O2:O32061)","v":92},{"$f":"SUM(P2:P32061)","v":5},{"$f":"SUM(Q2:Q32061)","v":0},{"$f":"SUM(R2:R32061)","v":32046},{"$f":"SUM(S2:S32061)","v":983},{"$f":"SUM(T2:T32061)","v":12},{"$f":"SUM(U2:U32061)","v":36}]