Supplementary Data 2: Gene Set Enrichment Analysis of significantly downregulated genes after 24 hours treatment of THP-1 cells with 3_M SPHINX31.,,,,,,,
,,,,,,,
Gene Sets,pvalue,FDR,overlap,Genes,setA,setB,universe
RB_P107_DN.V1_UP,4.52E-58,8.54E-56,52,"ASF1B,CCNE1,CCNE2,CCNF,CDC45,CDK2,CENPH,CENPK,CHAF1B,DCLRE1A,DHFR,DNA2,DNAJC9,E2F1,E2F8,FANCA,FEN1,GINS4,GMNN,GTSE1,HAUS8,INCENP,KIF4A,LIG1,MAD2L1,MCM2,MCM5,MCM6,MCM7,NCAPH,ORC6,PAQR4,PCNA,POLD1,POLE,POLE2,PRC1,RFC2,RFC3,RFC5,RHEBL1,RPA3,RPL39L,RRM1,RRM2,SIVA1,SLBP,STMN1,TCF19,TUBG1,WDHD1,WDR90",828,140,55765
RPS14_DN.V1_DN,7.78E-45,1.46E-42,48,"ARHGAP11A,ASNS,ATAD2,BCAT1,CBS,CDC20,CDC6,CDCA3,CHAC1,DEPDC1,DLGAP5,E2F8,ECT2,ERCC6L,ESPL1,EXO1,FBXO5,FOXRED2,FZD5,GAL,GINS2,INCENP,KIF15,KIF20A,KIF23,KIF2C,LRRC20,MCM10,MCM5,MKI67,MSH2,MYBL2,MYO19,NCAPH,NUP155,ORC1,PBK,PLK1,POLD1,PRC1,PSAT1,SLC29A1,SLC31A1,SUV39H2,TK1,TRIP13,TUBG1,ZWILCH",828,187,55765
CSR_LATE_UP.V1_UP,4.01E-41,7.50E-39,44,"ANLN,BIRC5,CCDC34,CCND3,CDC6,CDC7,CDCA8,CDK1,CLSPN,DIAPH3,DTYMK,EEF1E1,FABP5,FAM83D,FANCA,FEN1,FOXM1,GINS2,GINS3,GMNN,HAT1,IL7R,KCNC4,KIF22,LYAR,MCM3,MYBL2,MZT1,NETO2,NUF2,PBK,POLD1,RRM2,SHCBP1,TCF19,TRIP13,TSPAN13,TUBA4A,TUBG1,UBE2C,UHRF1,ZNF367,ZWILCH,ZWINT",828,172,55765
HOXA9_DN.V1_DN,1.20E-34,2.23E-32,41,"ACPP,ADM,APOBEC3B,ARHGAP11A,ATAD2,BCAT1,BRCA2,C1ORF106,C1ORF112,CBS,CD300A,CDC45,CDC6,CEP55,CIDEB,E2F8,FANCG,FANCI,GINS1,GINS3,GINS4,HELLS,KCTD15,MCM10,NET1,NRGN,ORC1,PLK4,PSIP1,RAB33A,RFWD3,RGS16,RNASEH2A,SLC29A1,SLC2A3,SLC38A1,TBC1D30,TEX15,TIPIN,TMEM106C,TRIB3",828,195,55765
E2F1_UP.V1_UP,1.10E-32,2.04E-30,39,"AURKB,BRCA2,BUB1,CDR2L,CHAF1B,CHEK1,CRYZ,DBF4,DLGAP5,DLX1,DNA2,E2F8,FANCM,FEN1,HMGB3,IVNS1ABP,KIFC1,LMNB1,MCM10,MCM4,NCAPH,PLK4,POLA2,PRC1,PTPRU,RRM1,SGOL1,SLBP,SLC20A1,SLC7A1,SMC2,STIL,TFAM,TK1,TYMS,TYRO3,UBE2T,VEGFA,WDHD1",828,189,55765
PRC2_EZH2_UP.V1_UP,3.93E-32,7.23E-30,39,"ADAMTS5,APLP1,AURKB,BARX1,BUB1,CDC25A,CDC45,DDB2,DEPDC1,DLGAP5,DNA2,DSCC1,ECT2,ETS1,HELLS,HJURP,KIF15,KIF4A,KNTC1,LMNB1,LRRC20,MCM10,MCM2,MLF1IP,MYBL2,NCAPH,OIP5,PCK2,POLR3G,PSPH,PSRC1,RAD54L,RFC4,SKP2,TACC3,TFAM,TTK,WDR76,XRCC3",828,195,55765
VEGF_A_UP.V1_DN,2.99E-26,5.47E-24,34,"ADAM9,BIRC5,BUB1,BUB1B,CCNB1,CCNE1,CDC45,CDKN3,CENPA,CRYZ,CSE1L,CTNNAL1,DBF4,DHFR,DLGAP5,EXO1,KIF11,KIF22,KIF23,LMNB1,MAD2L1,MCM4,NDC80,NR2F1,NUP155,PLK4,PTPRE,RFC4,RRM2,SLC4A7,SPAG5,TFAM,TMPO,TTK",828,193,55765
PRC2_EED_UP.V1_DN,4.40E-25,8.01E-23,33,"APLP1,ARRB2,ASF1B,BUB1B,C16ORF59,C1ORF112,CDC45,CDCA8,CHAF1B,CLSPN,DCLRE1B,ENO2,HELLS,INCENP,KIF23,KIF4A,LRRC20,MAP3K6,MCM10,MCM2,MCM5,MYBL2,ORC1,PFKFB4,PLK1,POLA2,POLD1,RAD54L,RANGAP1,RECQL4,TACC3,XRCC3,ZWILCH",828,193,55765
GCNP_SHH_UP_LATE.V1_UP,1.11E-24,2.01E-22,32,"AURKA,AURKB,CDC25A,CDC25C,CDK1,CHEK1,DLGAP5,E2F8,FANCM,INCENP,IVNS1ABP,KIF2C,KIFC1,LIG1,MCM10,MCM4,MCM5,MCM6,NUSAP1,PLK2,POLA2,PRC1,PSMC3IP,RRM1,RRM2,SDC2,SGOL1,SLC29A1,SMC2,TK1,TRIP13,UNG",828,183,55765
MTOR_UP.N4.V1_UP,1.36E-22,2.45E-20,31,"ADAM9,ADM,ARG2,ASNS,ATF3,BCAT1,CHAC1,CTSG,DDIT4,DNMT3B,FAM129A,GALE,GK,IL7R,KIF21B,MARS,NUP155,PCK2,PHGDH,PLS1,POLR3G,PSPH,SLC31A1,SLC39A14,SLC6A9,SLC7A11,SLC7A5,SLCO4A1,TRIB3,ULBP1,VEGFA",828,196,55765
NFE2L2.V2,1.87E-22,3.35E-20,45,"ACOT11,ACVRL1,ASNS,AXIN2,BCAT1,BRIP1,CBS,CCDC138,CCND3,CDC45,CHAC1,CYCS,DBF4,DHFR,ESCO2,FAM69A,FERMT1,GPT2,HJURP,ICMT,JDP2,MARS,MCM10,MCM3,MDFIC,MTBP,NEIL3,ORC1,PCK2,PHGDH,PSAT1,RRM2,SLC1A4,SLC7A11,SLCO4C1,STC2,STYK1,SUV39H2,TERT,TLR4,TMEM237,WDHD1,WHSC1,XYLB,ZNF367",828,481,55765
MEL18_DN.V1_UP,1.43E-18,2.55E-16,24,"ADM,C3AR1,CD83,CLSPN,DDIT4,ECM1,GAL,GPR3,HBEGF,IL7R,KIF21B,PLAUR,SLC1A4,SLC22A4,SLC29A1,SLC6A9,SLC7A11,SLC7A5,SLCO4A1,STC2,TGFBR3,TYRO3,VEGFA,WISP1",828,141,55765
STK33_SKM_DN,1.32E-17,2.34E-15,31,"ADAMTS5,ALDH1L2,ASNS,BACE2,C1ORF106,CCDC26,FAM84B,FERMT1,GPR84,LILRA2,MS4A3,PHACTR3,PLS1,PPM1H,PROCR,PROK2,PSPH,RGS16,SLCO4C1,SLPI,SPNS3,SPRY1,STAR,STC2,TANC1,TBC1D30,TEX15,TNFAIP8,TONSL,TSPAN13,TUBA4A",828,288,55765
E2F3_UP.V1_UP,3.32E-16,5.84E-14,25,"ATAD2,CCNE1,CCNE2,CD83,CSPG5,DCLRE1B,DTL,E2F7,ENO2,FANCA,FEN1,GINS1,HEY1,HSPA2,NR2F1,PCNA,POLE,POLE2,RECQL4,SHANK3,SNRNP25,TIAM1,TMEM106C,UNG,ZNF367",828,196,55765
RB_DN.V1_UP,1.80E-15,3.15E-13,21,"CCNE1,CCNE2,DNA2,DNAJC9,DSN1,HAT1,MCM6,MCM7,MSH6,PCNA,POLE2,RAD54L,RFC3,RRM2,SIVA1,SLBP,STMN1,TIMELESS,TIPIN,TUBG1,UBE2T",828,137,55765
ERB2_UP.V1_DN,3.71E-15,6.46E-13,24,"ADAM9,BTG3,DBF4,DEPDC1,DTL,ECT2,ERI2,FBXO5,HSPA13,HSPA4L,KLF10,MAD2L1,MSH2,MYBL1,NCAPG,PLK4,PSPH,RAD51AP1,RAD54B,RMI1,STIL,TIAM1,TOPBP1,TTK",828,197,55765
SRC_UP.V1_DN,4.31E-15,7.46E-13,23,"APITD1,ATAD2,CENPH,CHAC2,E2F8,GINS1,IL7R,LIG1,MAP3K6,MCM3,MCM4,MCM5,MIR17HG,OTUD6B,PHLDA2,PLK4,PRR19,RACGAP1,S1PR3,SPNS3,STK17B,SUV39H2,UHRF1",828,179,55765
BMI1_DN_MEL18_DN.V1_UP,5.84E-15,1.00E-12,21,"ADM,ADM2,ATF3,C3AR1,GADD45A,GAL,HBEGF,IL7R,KIF21B,MARCH3,PLAUR,PSAT1,SLC1A4,SLC22A4,SLC6A9,SLC7A11,SLC7A5,STC2,TRIB3,VEGFA,WEE1",828,145,55765
STK33_DN,7.27E-15,1.24E-12,28,"ALCAM,ASNS,BACE2,CCDC26,ENDOD1,FAM134B,FAM84B,FERMT1,GPT2,MS4A3,PIK3R3,PLS1,POLD1,PPM1H,PROK2,PSPH,RGS16,RMI2,SLC37A4,SLC38A5,SLCO4C1,SLPI,SPNS3,ST6GALNAC3,STAR,STC2,TEX15,TNFAIP8",828,289,55765
MTOR_UP.V1_UP,1.46E-14,2.48E-12,22,"AK4,ATF3,CDC20,CDK1,DBF4,EEF1E1,FABP5,HELLS,HSPE1,MCM5,MCM6,NEIL3,PCNA,PSAT1,RRM2,STMN1,TCF19,TIPIN,TNFRSF12A,UBE2C,UHRF1,USP18",828,170,55765
IL2_UP.V1_UP,2.00E-14,3.38E-12,23,"ABTB2,AP3M2,CDC25A,DHRS3,DUSP6,FZD5,HEG1,KCNG1,KCNK5,KCTD12,KIF21B,MPP6,NCS1,POLR3G,PRR7,RGS16,SLAMF1,SLC2A3,SLC7A5,SLCO4A1,TNFAIP8,TNFRSF12A,WDR62",828,192,55765
GCNP_SHH_UP_EARLY.V1_UP,2.38E-14,4.00E-12,22,"ANLN,AURKA,AURKB,CHEK1,DHFR,E2F8,FEN1,KIF4A,KIFC1,MCM10,MCM5,MCM6,MSH6,POLA2,PRC1,RPL39L,RRM1,SGOL1,SMC2,TRAIP,TYMS,UBE2T",828,174,55765
IL15_UP.V1_UP,1.63E-12,2.72E-10,21,"ACVRL1,AP3M2,APLP1,CCNE1,CDC25A,DHRS3,DUSP6,ECM1,ETV4,FZD5,HEG1,KCTD12,KIF21B,MPP6,POLR3G,RGS16,SLAMF1,SLC7A5,SLCO4A1,TNFAIP8,TNFRSF12A",828,192,55765
EGFR_UP.V1_UP,1.80E-12,2.99E-10,21,"ADM,APOBEC3B,ATF3,BACE2,CAPN2,CCL2,CEBPD,CTNNAL1,DRAM1,DUSP6,ETV5,GAL,GK,HBEGF,HSPA2,PTPRE,RGS16,S100P,SLC4A7,SLC7A11,TNFAIP8",828,193,55765
SNF5_DN.V1_UP,3.00E-12,4.95E-10,20,"AIF1,ATP1B1,AURKB,BUB1,C3AR1,CD48,COL15A1,DTL,FAM105A,HAT1,ITGB2,KIAA1524,KIF20A,MCM5,NCAPG2,RBL1,SLC2A3,TIPIN,UBE2C,ZWILCH",828,177,55765
ALK_DN.V1_UP,7.37E-12,1.21E-09,18,"AIF1,ASNS,CBS,CHAC1,CLSPN,CTH,DDIT4,ETV1,MPO,PCK2,PSAT1,SLC1A3,SLC6A9,SLC7A11,SLC7A5,STC2,TRIB3,VEGFA",828,145,55765
RPS14_DN.V1_UP,1.36E-11,2.22E-09,20,"AIF1,ALCAM,C3AR1,CCL2,CD300A,CDKN1A,CLEC5A,CTSG,DNAJC22,GNB5,HEY1,ITGB2,KCTD12,LST1,MDFIC,MNDA,PLK2,PTPRE,RASGRP3,TRIM36",828,192,55765
RB_P130_DN.V1_UP,1.75E-11,2.84E-09,17,"AURKA,AURKB,BIRC5,CDC7,CDK1,CMTM7,FAM64A,FST,KIF20A,KIF22,ORC1,RACGAP1,RGS16,SLC29A1,SLC43A3,TK1,UBE2C",828,133,55765
CORDENONSI_YAP_CONSERVED_SIGNATURE,4.07E-11,6.55E-09,12,"BIRC5,CDC20,ECT2,ETV5,GGH,ITGB2,LHFP,MDFIC,PHGDH,SHCBP1,STMN1,TK1",828,57,55765
STK33_NOMO_DN,7.27E-10,1.16E-07,22,"ACPP,ALCAM,ASNS,BACE2,CLEC5A,FAM134B,FERMT1,GPT2,HSPA4L,JDP2,MZT1,PIK3R3,PLS1,POLD1,PROK2,PSPH,RMI2,SLC37A4,SLC39A14,ST6GALNAC3,STAR,TEX15",828,292,55765
SIRNA_EIF4GI_DN,2.97E-09,4.72E-07,13,"APITD1,CCL2,CDC6,EIF5A2,FAM111A,MYO19,PSMC3IP,SHCBP1,SLC31A1,SLC43A3,SPTSSA,SRPK1,TRIP13",828,99,55765
BMI1_DN.V1_UP,6.39E-09,1.01E-06,15,"C3AR1,CLSPN,CSPG5,DHRS3,FZD5,GAL,HBEGF,IL7R,KCNC4,MARCH3,SLC1A4,SLC29A1,SLC7A5,SLCO4A1,STC2",828,147,55765
TBK1.DF_UP,1.90E-08,2.98E-06,20,"ATF3,BTG3,CD83,CXCL2,DNMT3B,ENDOD1,ENO2,FAM69A,GINS1,HBEGF,HSPA2,MYBL1,NETO2,PASK,PLAUR,PNP,RAD51AP1,SLC2A3,TNFAIP8,TRIM36",828,290,55765
CSR_EARLY_UP.V1_UP,2.83E-08,4.41E-06,15,"EHD4,ETS1,FAM107B,GAL,GATA2,HBEGF,KLF10,NET1,PHLPP2,PLAUR,PNP,RFK,SLC37A4,SPRY4,TNFRSF12A",828,164,55765
JNK_DN.V1_DN,3.42E-08,5.30E-06,16,"ACVRL1,APLP1,BLM,CDC45,CDKN3,ETS1,ITGB2,KIF22,KNTC1,NRGN,PAQR4,PLK1,POLD1,RGS16,SPRY1,UBE2C",828,191,55765
ATF2_UP.V1_UP,3.68E-08,5.67E-06,16,"ADM2,C3AR1,CD19,CENPO,DTL,FOXM1,GINS2,GINS3,LIG1,MELK,MLF1IP,NCAPG,PLK4,POLD1,RAD51,TK1",828,192,55765
RAF_UP.V1_DN,4.25E-08,6.50E-06,16,"AK4,ALCAM,BTG3,CTNNAL1,DDIT4,IGFBP4,KITLG,MYBL1,NEDD4L,PLK2,PLS1,PPM1E,SDC2,SLC19A2,STC2,TBC1D30",828,194,55765
MEK_UP.V1_UP,4.91E-08,7.46E-06,16,"ADM,BACE2,C1ORF106,CAPN2,ENO2,EPHA1,ETV5,FAM105A,GAL,LHFP,NT5DC2,PTPRE,PTPRU,S100P,SLC7A11,TNFAIP8",828,196,55765
ERB2_UP.V1_UP,2.12E-07,3.20E-05,15,"APLP1,APOBEC3B,BACE2,CAPN2,DRAM1,DUSP6,ENO2,ETV5,FAM129A,HEY1,HSPA2,PTPRE,PTPRU,S100P,SERPINA1",828,191,55765
EGFR_UP.V1_DN,2.96E-07,4.44E-05,15,"BRIP1,BTG3,DEPDC1,DTL,E2F8,HSPA4L,KIF11,MLF1IP,NCAPG2,NET1,PRR7,PSPH,RFWD3,SGCB,STIL",828,196,55765
RAF_UP.V1_UP,2.96E-07,4.44E-05,15,"BACE2,CAPN2,CCR1,CEBPD,ETV5,FYN,FZD5,GATA2,HBEGF,HEG1,HSPA2,KCTD12,NDC80,S100P,TNFAIP8",828,196,55765
PDGF_UP.V1_UP,3.22E-07,4.77E-05,13,"ACOT11,ADAM9,ATF3,CCNE1,CDC25A,CDC6,CDKN1A,DDIT4,GADD45A,HSPA2,KLF10,SLC20A1,SLC7A5",828,146,55765
RB_DN.V1_DN,3.13E-06,0.00046011,11,"BASP1,CHAC1,CTNNAL1,DDIT4,GADD45A,H19,S1PR5,SLC7A5,STC2,TUBA4A,USP18",828,126,55765
ESC_J1_UP_LATE.V1_DN,4.93E-06,0.00071978,13,"DOC2A,E2F8,ERCC6L,ETV4,FAM129A,PASK,PDSS1,PHLDA2,POLA1,POLE,SNTB2,SPRY4,TRAIP",828,186,55765
CRX_DN.V1_UP,6.56E-06,0.0009512,11,"ARG2,BUB1B,DPF3,FAM107B,FAM161A,PAQR4,RAD51,SNTB2,STK17B,SUV39H2,WISP1",828,136,55765
KRAS.DF.V1_UP,7.37E-06,0.00106128,13,"AURKB,CHRNA5,CRYZ,DDB2,DLGAP5,DSN1,E2F8,HSPA2,MAP3K6,PROCR,S100P,SLC22A4,SLC4A7",828,193,55765
HOXA9_DN.V1_UP,7.79E-06,0.00111397,13,"ADAM9,FAM105A,FYN,GADD45A,HPSE,MNDA,MPO,MS4A3,PIK3R3,PLK2,PTPRE,SLC22A4,STK39",828,194,55765
LTE2_UP.V1_DN,8.70E-06,0.0012354,13,"ATF3,BTG3,GADD45A,GAL,HSPA13,OAS3,PPM1E,PSAT1,RFWD3,SLC7A11,STC2,SVIL,USP18",828,196,55765
ESC_J1_UP_EARLY.V1_UP,2.14E-05,0.0030174,12,"ADM,CIDEB,FAM134B,GPRIN1,HEY1,MPP2,NEK2,NHSL1,NLRP3,RAB3IL1,SERPINE2,TMEM106C",828,183,55765
NOTCH_DN.V1_DN,2.95E-05,0.00413,12,"C3AR1,CIDEB,DOC2A,DRAM1,E2F2,FCN1,IL7R,RAB3IL1,RPL39L,SLC28A3,SLPI,SPRY4",828,189,55765
ESC_J1_UP_LATE.V1_UP,3.27E-05,0.0045453,12,"ATF3,CIDEB,DRAM1,FAM134B,FST,H19,IGFBP4,PRICKLE1,RAB11FIP5,SERPINE2,TGFBR3,TNFRSF12A",828,191,55765
STK33_SKM_UP,3.52E-05,0.0048576,15,"ADM,ASB2,CDKN1A,ETV1,HBEGF,HECW2,KITLG,MNS1,NFKBIZ,PLK2,RASGRP3,SH2B3,SIPA1L2,SLC7A11,SUCNR1",828,290,55765
PRC2_SUZ12_UP.V1_UP,3.81E-05,0.0052197,12,"ACVRL1,ARHGEF16,ARRB2,CCNE1,CHEK1,IL1RN,KLHL23,ORC1,POLA2,RAD54L,RECQL4,ZWILCH",828,194,55765
PKCA_DN.V1_DN,4.49E-05,0.0061064,11,"ADM,BARD1,BATF3,CD19,FANCI,MAP3K6,NFKBIZ,PROCR,PSAT1,SNTB2,TNFRSF12A",828,167,55765
CRX_NRL_DN.V1_UP,5.00E-05,0.00675,10,"ARG2,BUB1B,DHRS3,DIAPH3,DPF3,GADD45A,PAQR4,SNTB2,STK17B,WISP1",828,140,55765
WNT_UP.V1_DN,5.28E-05,0.0070752,11,"CD48,DPF3,ETV4,HEY1,KITLG,LSR,NT5DC2,TANC1,TGFBR3,USP18,VEGFA",828,170,55765
TBK1.DN.48HRS_DN,9.59E-05,0.0127547,6,"BIRC5,CDK1,CRYZ,CTNNAL1,GALE,TRIB3",828,50,55765
AKT_UP_MTOR_DN.V1_DN,0.000102,0.013464,11,"CBS,CENPQ,KCTD12,MCM6,PHLDA2,PSAT1,S1PR3,SLC37A4,SLC7A5,TIPIN,WEE1",828,183,55765
AKT_UP_MTOR_DN.V1_UP,0.000107,0.014017,11,"AK4,ATF3,BACE2,FAM129A,HBEGF,KCNK5,KLF10,MPP2,PLK2,RAB3IP,TNFRSF12A",828,184,55765
CSR_EARLY_UP.V1_DN,0.000111,0.01443,10,"ADM,ALDH1L2,CYP2R1,DHRS3,GRHL1,RBFOX2,SKP2,STC2,STOX1,WEE1",828,154,55765
ESC_V6.5_UP_LATE.V1_DN,0.000118,0.015222,11,"CHAC1,CTH,DCLRE1B,E2F8,ETV4,FZD5,GADD45A,PDSS1,POLA1,SPRY4,TRIB3",828,186,55765
CAHOY_ASTROCYTIC,0.000128,0.016384,8,"ASNS,BCAT1,CBS,FGD6,GABRG1,GRHL1,SLC7A11,VEGFA",828,100,55765
CYCLIN_D1_UP.V1_UP,0.00013,0.01651,11,"BIN1,BLM,CEBPD,CHRNA5,ETV4,FZD5,GADD45A,KIF22,MKI67,SHC3,SLC6A9",828,188,55765
PIGF_UP.V1_UP,0.000149,0.018774,11,"ADAM9,CCPG1,CRYZ,GMFB,HSPA13,NUP155,PSPH,RASGRP3,RFK,SLC4A7,TGFBR3",828,191,55765
ATF2_S_UP.V1_UP,0.000164,0.0205,11,"BARX1,C3AR1,CDKN3,FOXM1,KIF20A,KIF23,MLF1IP,PPM1H,RPL39L,TK1,UNG",828,193,55765
PRC2_EZH2_UP.V1_DN,0.000171,0.021204,11,"ETV1,ETV4,FAM69A,HBEGF,KCTD12,RGS16,SLC19A2,SLC2A3,SLPI,TSPAN13,TUBA4A",828,194,55765
CRX_DN.V1_DN,0.000188,0.023124,9,"CDKN1A,CEBPD,CHAC1,CTNNAL1,FABP5,GDAP1L1,KLF10,MPP6,TNFRSF12A",828,134,55765
NRL_DN.V1_UP,0.00021,0.02562,9,"ARG2,CCNA2,DHRS3,DPF3,GADD45A,NUF2,SNTB2,STK17B,WISP1",828,136,55765
AKT_UP.V1_UP,0.000273,0.033033,10,"AK4,ATF3,BACE2,FABP5,FAM129A,KCNK5,PLK2,ROPN1L,TNFRSF12A,UBE2C",828,172,55765
KRAS.PROSTATE_UP.V1_UP,0.000306,0.03672,9,"ADM2,C17ORF53,CYP2R1,ETV5,GRK5,HAL,IL7R,ITGB2,TLR4",828,143,55765
PDGF_ERK_DN.V1_DN,0.000414,0.049266,9,"ADM,ARHGEF16,CCNF,CDR2L,DUSP6,IL7R,KLF10,KLHL25,TRAIP",828,149,55765
TBK1.DF_DN,0.000415,0.049266,13,"CCNE2,CDCA4,DSN1,IL1RN,KIF14,LMNB1,MSH2,RFWD3,SERPINE2,SLC37A4,SNTB2,TFAM,ZWINT",828,287,55765
MYC_UP.V1_DN,0.000428,0.050076,10,"CDCA8,FGD6,GINS1,GRHL1,HEG1,MAP3K6,PLK1,PSMC3IP,PTPRE,SPNS3",828,182,55765
P53_DN.V1_UP,0.000703,0.081548,10,"ADM,DHRS3,FYN,LSR,NDC80,NR2F1,OIP5,S100P,TUBA4A,USP1",828,194,55765
KRAS.50_UP.V1_UP,0.00072,0.0828,5,"ETV1,ETV5,HEY1,ITGB2,TERT",828,48,55765
LEF1_UP.V1_UP,0.000732,0.083448,10,"ARG2,CBS,CTH,KCNG1,KCTD12,MPP6,SLC2A3,SLC43A3,STC2,TREML2",828,195,55765