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{"sheet":"STENvNINF Hyper","index":0,"n_rows":1287,"n_cols":9,"rows_kept":1287,"cut":false,"hidden":false,"merged":[]}
["Database","Geneset_ID","Description","pvalue","padj","N_background","N_observed","Average_gene_length","EntrezID_set"]
["Reactome","R-HSA-1474244","Extracellular matrix organization",4.897049941123043E-9,5.2937109863540094E-6,298.0,64.0,161377.61744966442,"1277, 1291, 2006, 2192, 3655, 7148, 92291, 650, 1289, 1303, 1307, 2199, 3689, 7077, 7143, 56999, 91522, 140766, 440854, 652, 655, 831, 999, 1278, 1282, 1293, 1295, 1404, 1462, 1513, 1514, 1634, 2200, 2201, 2331, 3695, 3910, 3918, 4060, 4312, 4314, 5034, 5118, 5352, 6382, 7057, 8076, 8200, 8425, 8785, 8974, 9509, 11096, 27302, 50848, 55214, 80781, 84034, 169044, 170692, 255631, 375790, 388743, 100422894"]
["KEGG Pathways","hsa05217","Basal cell carcinoma",3.065389572575193E-8,6.284048623779146E-6,55.0,21.0,187471.14545454545,"11211, 51176, 6934, 650, 1499, 2736, 5727, 7475, 8313, 8321, 324, 652, 1855, 2737, 7474, 7480, 7481, 7482, 51384, 80326, 83439"]
["Reactome","R-HSA-1474290","Collagen formation",3.0111182396123213E-5,0.010850062723403064,93.0,25.0,177492.60215053763,"1277, 1291, 3655, 1289, 1303, 1307, 91522, 140766, 1278, 1282, 1293, 1295, 1514, 3918, 4314, 5034, 5118, 5352, 8974, 9509, 55214, 80781, 169044, 255631, 100422894"]
["Reactome","R-HSA-2129379","Molecules associated with elastic fibres",5.993225306743543E-5,0.012402261136747248,37.0,13.0,165691.37837837837,"2006, 2192, 650, 2199, 652, 655, 2200, 2201, 8076, 8200, 8425, 27302, 84034"]
["Reactome","R-HSA-1474228","Degradation of the extracellular matrix",6.821588495435618E-5,0.012402261136747248,141.0,30.0,141243.97872340426,"1277, 1291, 2006, 92291, 1289, 1303, 1307, 7077, 56999, 91522, 440854, 831, 999, 1278, 1282, 1293, 1295, 1513, 1514, 1634, 2200, 2201, 3918, 4312, 4314, 11096, 80781, 170692, 388743, 100422894"]
["Reactome","R-HSA-3781865","Diseases of glycosylation",6.883771213735754E-5,0.012402261136747248,78.0,23.0,219267.14102564103,"7058, 10417, 2817, 54437, 56999, 79875, 140766, 170691, 1462, 1634, 2331, 4060, 4585, 4958, 6382, 7057, 9509, 11096, 54507, 57188, 80731, 170692, 375790"]
["Reactome","R-HSA-1650814","Collagen biosynthesis and modifying enzymes",2.542929650935861E-4,0.039270099323738074,70.0,20.0,202314.55714285714,"1277, 1291, 1289, 1303, 1307, 91522, 140766, 1278, 1282, 1293, 1295, 5034, 5118, 5352, 8974, 9509, 55214, 80781, 169044, 255631"]
["KEGG Pathways","hsa04916","Melanogenesis",2.5634555679660773E-4,0.026275419571652293,100.0,24.0,193784.11,"11211, 51176, 6934, 810, 1499, 4286, 7475, 8321, 107, 1387, 1855, 2778, 5330, 5567, 7306, 7474, 7480, 7481, 7482, 51384, 80326, 83439, 90993, 196883"]
["Reactome","R-HSA-1566948","Elastic fibre formation",3.3658526813149024E-4,0.04548108435626762,44.0,13.0,151321.81818181818,"2006, 2192, 650, 2199, 652, 655, 2200, 2201, 8076, 8200, 8425, 27302, 84034"]
["KEGG Pathways","hsa04340","Hedgehog signaling pathway",4.1479719539475496E-4,0.028344475018641586,56.0,16.0,198174.8392857143,"650, 2736, 5727, 7475, 652, 655, 1455, 2737, 5567, 7474, 7480, 7481, 7482, 50846, 51384, 80326"]
["Reactome","R-HSA-5083635","Defective B3GALTL causes Peters-plus syndrome (PpS)",6.860982340497688E-4,0.0824080212230889,35.0,14.0,293522.65714285715,"7058, 10417, 54437, 56999, 79875, 140766, 170691, 7057, 9509, 11096, 54507, 57188, 80731, 170692"]
["Reactome","R-HSA-193648","NRAGE signals death through JNK",8.236578493839236E-4,0.08636465174487744,59.0,17.0,174894.3220338983,"27237, 23263, 4804, 7204, 7410, 8874, 8997, 9639, 9828, 10018, 10451, 10672, 11214, 26230, 50650, 54848, 57449"]
["Reactome","R-HSA-3000480","Scavenging by Class A Receptors",8.788262434723884E-4,0.08636465174487744,21.0,7.0,167079.2380952381,"1277, 338, 348, 1278, 1282, 5648, 81035"]
["KEGG Pathways","hsa05323","Rheumatoid arthritis",8.857895364161278E-4,0.04539671374132655,89.0,16.0,100111.2808988764,"3689, 6387, 525, 528, 1435, 1513, 1514, 3458, 3553, 3600, 4312, 4314, 7099, 10312, 10673, 90423"]
["Reactome","R-HSA-2173782","Binding and Uptake of Ligands by Scavenger Receptors",0.0012284557888157849,0.09385094124971431,43.0,10.0,121390.55813953489,"1277, 338, 348, 1278, 1282, 4035, 5648, 8542, 23166, 81035"]
["Reactome","R-HSA-174800","Chylomicron-mediated lipid transport",0.0013888929234127934,0.09385094124971431,26.0,7.0,125942.65384615384,"338, 337, 348, 3990, 5034, 5046, 26119"]
["Reactome","R-HSA-5173214","O-glycosylation of TSR domain-containing proteins",0.0014835764007971636,0.09385094124971431,37.0,14.0,289827.5945945946,"7058, 10417, 54437, 56999, 79875, 140766, 170691, 7057, 9509, 11096, 54507, 57188, 80731, 170692"]
["Reactome","R-HSA-6809371","Formation of the cornified envelope",0.0015038695262539021,0.09385094124971431,125.0,15.0,48833.808,"3851, 3852, 3853, 3855, 3889, 3890, 5046, 5493, 5652, 9119, 23254, 112802, 126638, 144501, 192666"]
["Reactome","R-HSA-2022090","Assembly of collagen fibrils and other multimeric structures",0.0015554784827642636,0.09385094124971431,64.0,16.0,163461.609375,"1277, 1291, 3655, 1289, 1303, 1278, 1282, 1293, 1295, 1514, 3918, 4314, 5118, 80781, 255631, 100422894"]
["Reactome","R-HSA-1500931","Cell-Cell communication",0.0015651547841093291,0.09385094124971431,140.0,30.0,276163.90714285715,"3655, 5829, 1012, 1499, 29780, 56288, 999, 1000, 1001, 1002, 1003, 1006, 2533, 2534, 3852, 3918, 4690, 5295, 5818, 6714, 8440, 9423, 10207, 23705, 24146, 50848, 54751, 57453, 653509, 100422894"]
["Reactome","R-HSA-216083","Integrin cell surface interactions",0.0015995795351106115,0.09385094124971431,87.0,19.0,123549.4367816092,"1277, 1291, 3655, 1289, 1307, 3689, 91522, 999, 1278, 1282, 1293, 1295, 2200, 3695, 4060, 7057, 50848, 80781, 375790"]
["Reactome","R-HSA-446728","Cell junction organization",0.0020015399417459626,0.10818323385136927,91.0,21.0,304006.37362637365,"3655, 5829, 1012, 1499, 29780, 56288, 999, 1000, 1001, 1002, 1003, 1006, 3852, 3918, 5818, 10207, 23705, 24146, 50848, 54751, 100422894"]
["Reactome","R-HSA-3238698","WNT ligand biogenesis and trafficking",0.0023345778396181285,0.12017517355367605,26.0,7.0,87913.03846153847,"7475, 7474, 7480, 7481, 7482, 51384, 80326"]
["Reactome","R-HSA-174824","Lipoprotein metabolism",0.0026321021924560176,0.12933193045658886,71.0,14.0,125952.22535211267,"338, 29116, 337, 348, 2534, 3069, 3931, 3990, 5034, 5046, 5567, 26119, 57552, 100616211"]
["Reactome","R-HSA-3560782","Diseases associated with glycosaminoglycan metabolism",0.0029079105516199286,0.13667179592613665,25.0,8.0,209582.64,"2817, 1462, 1634, 2331, 4060, 4958, 6382, 375790"]
["KEGG Pathways","hsa05200","Pathways in cancer",0.0035074173379400155,0.11983675904628385,326.0,54.0,178519.0736196319,"4088, 11211, 5915, 51176, 3655, 6934, 650, 1499, 2736, 4286, 5727, 7424, 7475, 8313, 8321, 324, 595, 652, 999, 1282, 1387, 1612, 1855, 1956, 2252, 2256, 2260, 2261, 2263, 2308, 2737, 3910, 3918, 4089, 4312, 5293, 5295, 5900, 5914, 5925, 6513, 7187, 7474, 7480, 7481, 7482, 7704, 9915, 9965, 10000, 51384, 80326, 83439, 83593"]
["Reactome","R-HSA-1442490","Collagen degradation",0.003577527018789118,0.16113777947129318,66.0,15.0,140558.81818181818,"1277, 1291, 1289, 1303, 1307, 91522, 1278, 1282, 1293, 1295, 1513, 1514, 4312, 4314, 80781"]
["Reactome","R-HSA-73923","Lipid digestion, mobilization, and transport",0.004307604244473703,0.18626080753104293,110.0,18.0,105497.86363636363,"338, 29116, 337, 348, 2534, 3069, 3931, 3990, 3991, 5034, 5046, 5501, 5567, 11343, 26119, 57552, 646486, 100616211"]
["Reactome","R-HSA-204998","Cell death signalling via NRAGE, NRIF and NADE",0.00467161858194538,0.19423152642626754,75.0,17.0,148395.25333333333,"27237, 23263, 4804, 7204, 7410, 8874, 8997, 9639, 9828, 10018, 10451, 10672, 11214, 26230, 50650, 54848, 57449"]
["Reactome","R-HSA-3906995","Diseases associated with O-glycosylation of proteins",0.00515738421678128,0.20648638290150234,53.0,15.0,223835.30188679244,"7058, 10417, 54437, 56999, 79875, 140766, 170691, 4585, 7057, 9509, 11096, 54507, 57188, 80731, 170692"]
["KEGG Pathways","hsa04350","TGF-beta signaling pathway",0.005984484331061204,0.14496733813491264,84.0,19.0,218078.58333333334,"4088, 5308, 7058, 650, 90, 652, 655, 1387, 1634, 3458, 4086, 4089, 4838, 7027, 7057, 8200, 10637, 83729, 151449"]
["KEGG Pathways","hsa04310","Wnt signaling pathway",0.006242564672924174,0.14496733813491264,150.0,29.0,191688.12666666668,"4088, 11211, 51176, 6477, 6934, 1499, 7475, 8313, 8321, 81839, 324, 595, 894, 1387, 1855, 4089, 4772, 5330, 5567, 7474, 7480, 7481, 7482, 10023, 23002, 51384, 80326, 83439, 85409"]
["Reactome","R-HSA-416482","G alpha (12/13) signalling events",0.006586591659038088,0.25428948512214905,87.0,19.0,176694.06896551725,"27237, 23263, 146, 2768, 2793, 5295, 7204, 7410, 8874, 8997, 9639, 9828, 10451, 10672, 11214, 26230, 50650, 54848, 57449"]
["KEGG Pathways","hsa04974","Protein digestion and absorption",0.006957126797075362,0.14496733813491264,80.0,16.0,144484.375,"1277, 1291, 2006, 1289, 1303, 6546, 478, 486, 1278, 1282, 1293, 3784, 6510, 9056, 10008, 80781"]
["KEGG Pathways","hsa05219","Bladder cancer",0.007403221636491289,0.14496733813491264,42.0,9.0,104225.90476190476,"7424, 595, 999, 1612, 1956, 2261, 4312, 5925, 7057"]
["KEGG Pathways","hsa04920","Adipocytokine signaling pathway",0.007778735216995312,0.14496733813491264,68.0,13.0,130391.05882352941,"10891, 51422, 1374, 2180, 3952, 6513, 8660, 9021, 9370, 10000, 23305, 57818, 84254"]
["Reactome","R-HSA-193704","p75 NTR receptor-mediated signalling",0.009720139234160315,0.3450081748023326,97.0,19.0,139666.82474226804,"27237, 23263, 4804, 7204, 7410, 8874, 8997, 9639, 9828, 10018, 10451, 10672, 11214, 26230, 50650, 54848, 57142, 57449, 84894"]
["Reactome","R-HSA-195721","Signaling by Wnt",0.010453635981773117,0.3450081748023326,323.0,42.0,118199.13003095976,"51176, 6934, 55553, 1499, 3708, 7090, 7475, 8313, 8321, 440193, 324, 1212, 1387, 1455, 1855, 2793, 3709, 4772, 4920, 5330, 5689, 6597, 6662, 7089, 7474, 7480, 7481, 7482, 8353, 8452, 9736, 9861, 10023, 23002, 23072, 27327, 50964, 51339, 51384, 57690, 80326, 83439"]
["Reactome","R-HSA-1368082","RORA activates gene expression",0.010499545088437942,0.3450081748023326,28.0,9.0,274400.14285714284,"6095, 10499, 10891, 1374, 1387, 4862, 8204, 9572, 80205"]
["Reactome","R-HSA-6805567","Keratinization",0.010883315010783415,0.3450081748023326,212.0,17.0,36435.72169811321,"3851, 3852, 3853, 3855, 3889, 3890, 5046, 5493, 5652, 9119, 23254, 112802, 126638, 144501, 192666, 386674, 386679"]
["Reactome","R-HSA-419037","NCAM1 interactions",0.011182948897374652,0.3450081748023326,43.0,12.0,210586.37209302327,"2675, 1291, 783, 1289, 8912, 8913, 775, 1282, 1293, 2668, 2674, 375790"]
["KEGG Pathways","hsa04970","Salivary secretion",0.011280557465687732,0.1927095233721654,86.0,18.0,216330.06976744186,"810, 3708, 107, 146, 154, 155, 478, 486, 491, 1131, 2778, 3709, 4025, 4842, 5330, 5567, 6522, 196883"]
["Reactome","R-HSA-373080","Class B/2 (Secretin family receptors)",0.011489633943463435,0.3450081748023326,91.0,16.0,112348.84615384616,"11211, 5727, 7475, 8321, 2691, 2778, 2793, 5744, 7474, 7480, 7481, 7482, 10268, 50846, 51384, 80326"]
["Reactome","R-HSA-8948216","Collagen chain trimerization",0.012722256838531107,0.3716962065527602,47.0,13.0,207506.0,"1277, 1291, 1289, 1303, 1307, 91522, 1278, 1282, 1293, 1295, 80781, 169044, 255631"]
["KEGG Pathways","hsa04971","Gastric acid secretion",0.012946351404312436,0.20415400291415767,73.0,16.0,203410.34246575343,"3274, 810, 3708, 107, 478, 1131, 2778, 3709, 3773, 3784, 4638, 5330, 5567, 6522, 54207, 196883"]
["Reactome","R-HSA-1266738","Developmental Biology",0.014496680162596714,0.4018182373273602,1075.0,129.0,156032.74325581396,"84448, 4088, 9612, 2675, 5915, 7026, 286, 1291, 6477, 9935, 783, 1289, 1499, 1846, 2049, 2817, 3642, 4205, 4211, 5362, 6092, 6925, 8912, 8913, 10154, 10499, 10891, 27086, 57522, 80031, 80824, 287, 775, 1000, 1002, 1052, 1212, 1282, 1293, 1387, 1808, 1847, 1848, 1946, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2494, 2534, 2668, 2674, 2887, 2903, 2905, 3211, 3851, 3852, 3853, 3855, 3889, 3890, 3952, 4089, 4627, 4656, 4690, 4838, 5046, 5080, 5087, 5293, 5295, 5493, 5567, 5652, 5689, 5909, 5914, 6196, 6585, 6714, 6928, 6938, 7204, 7410, 7480, 8353, 8440, 8452, 8660, 8828, 8829, 8874, 8997, 9119, 9314, 9353, 9370, 9423, 9542, 9861, 9965, 10000, 10371, 10451, 10486, 10637, 11091, 11221, 22821, 23254, 56963, 57698, 64218, 80205, 91584, 112802, 126638, 144501, 153090, 192666, 375790, 386674, 386679"]
["Reactome","R-HSA-163560","Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis",0.015136369129084282,0.4090603757135027,20.0,5.0,85166.45,"3991, 5501, 5567, 11343, 646486"]
["KEGG Pathways","hsa04020","Calcium signaling pathway",0.016889968581568483,0.24731739708725278,176.0,33.0,202923.1875,"3274, 6262, 623, 810, 3708, 5257, 6546, 8912, 8913, 107, 146, 154, 155, 185, 491, 773, 775, 1128, 1131, 1956, 2066, 2778, 2903, 2905, 3706, 3709, 4638, 4842, 5330, 5567, 7201, 8877, 196883"]
["Reactome","R-HSA-4086398","Ca2+ pathway",0.017036319484731097,0.43848241340462657,60.0,13.0,155875.71666666667,"51176, 6934, 1499, 3708, 2793, 3709, 4772, 5330, 7474, 7481, 27327, 57690, 83439"]
["Reactome","R-HSA-201722","Formation of the beta-catenin:TCF transactivating complex",0.01869654644063303,0.4700224814494025,86.0,10.0,88147.0,"51176, 6934, 1499, 7090, 8313, 1387, 6597, 7089, 8353, 83439"]
["KEGG Pathways","hsa05213","Endometrial cancer",0.01968999050603481,0.254423750456489,52.0,12.0,209216.92307692306,"51176, 6934, 1499, 8313, 324, 595, 999, 1956, 5293, 5295, 10000, 83439"]
["Reactome","R-HSA-2871809","FCERI mediated Ca+2 mobilization",0.02075697375317561,0.49862863615961855,32.0,8.0,141891.5625,"3708, 3702, 3709, 3937, 4772, 7006, 7410, 10451"]
["KEGG Pathways","hsa04510","Focal adhesion",0.021394065310888954,0.254423750456489,200.0,34.0,166866.095,"1277, 1291, 3655, 5829, 7058, 7148, 1289, 1499, 7143, 7424, 29780, 595, 894, 1278, 1282, 1293, 1956, 2317, 2534, 2889, 3695, 3910, 3918, 4638, 5293, 5295, 5501, 6714, 7057, 7410, 10000, 10451, 83660, 93408"]
["KEGG Pathways","hsa04330","Notch signaling pathway",0.024924451399224983,0.254423750456489,47.0,8.0,96358.87234042553,"9612, 28514, 1387, 1855, 3714, 3955, 23220, 388585"]
["KEGG Pathways","hsa04973","Carbohydrate digestion and absorption",0.025029935318343965,0.254423750456489,42.0,9.0,184323.52380952382,"8972, 478, 486, 5293, 5295, 5330, 6518, 10000, 57818"]
["KEGG Pathways","hsa04520","Adherens junction",0.025097315434943743,0.254423750456489,73.0,16.0,218789.90410958903,"4088, 51176, 6934, 1499, 10458, 56288, 999, 1387, 1956, 2260, 2534, 4089, 5818, 6615, 6714, 83439"]
["Reactome","R-HSA-163685","Integration of energy metabolism",0.025175441076814912,0.5669719125841025,110.0,20.0,156052.4909090909,"152, 783, 3708, 9254, 11069, 51422, 107, 773, 775, 1131, 2778, 2793, 3709, 4082, 5330, 5567, 5575, 6513, 9370, 196883"]
["KEGG Pathways","hsa05210","Colorectal cancer",0.026994045109297087,0.254423750456489,62.0,13.0,195785.7258064516,"4088, 51176, 6934, 1499, 8313, 324, 595, 4089, 5293, 5295, 5900, 10000, 83439"]
["Reactome","R-HSA-3000178","ECM proteoglycans",0.02784973998264175,0.5847322357096726,76.0,16.0,165656.38157894736,"1277, 1291, 7148, 1289, 7143, 1278, 1282, 1293, 1404, 1462, 1634, 2331, 3910, 4060, 8785, 375790"]
["Reactome","R-HSA-2029480","Fcgamma receptor (FCGR) dependent phagocytosis",0.028127730117394053,0.5847322357096726,86.0,16.0,142448.17441860464,"3708, 10458, 919, 2534, 3709, 4627, 4650, 4690, 5295, 5580, 6714, 7410, 7456, 9844, 10451, 26999"]
["Reactome","R-HSA-1181150","Signaling by NODAL",0.02934740155816125,0.5985762468749493,19.0,5.0,141897.05263157896,"4088, 4089, 4838, 5046, 10637"]
["KEGG Pathways","hsa04976","Bile secretion",0.029505476435316803,0.254423750456489,71.0,14.0,163770.45070422534,"107, 478, 486, 2778, 5244, 5567, 6513, 6522, 6579, 8647, 57552, 123264, 196883, 200931"]
["KEGG Pathways","hsa04966","Collecting duct acid secretion",0.029681181511219887,0.254423750456489,27.0,5.0,66427.55555555556,"525, 528, 10312, 10723, 90423"]
["KEGG Pathways","hsa04912","GnRH signaling pathway",0.029786195175393836,0.254423750456489,99.0,17.0,167782.88888888888,"810, 3708, 107, 775, 1081, 1956, 2778, 3709, 4214, 4216, 5330, 5567, 5580, 6416, 6714, 50487, 196883"]
["Reactome","R-HSA-381426","Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",0.030203690147646445,0.6040898924726809,21.0,5.0,128492.57142857143,"3484, 3485, 3489, 4312, 5069"]
["Reactome","R-HSA-400253","Circadian Clock",0.030756808524247482,0.6040898924726809,69.0,14.0,181015.5652173913,"10743, 6095, 10499, 10891, 25819, 1374, 1387, 2155, 4862, 5501, 8204, 9572, 80205, 150094"]
["Reactome","R-HSA-180292","GAB1 signalosome",0.03129420349534702,0.6040898924726809,128.0,23.0,173680.9453125,"5829, 55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 10000, 23239, 27327, 29851, 55824, 57690"]
["Reactome","R-HSA-422356","Regulation of insulin secretion",0.032791007342831587,0.6119536497887061,80.0,16.0,176112.2375,"152, 783, 3708, 9254, 11069, 773, 775, 1131, 2778, 2793, 3709, 4082, 5330, 5567, 5575, 6513"]
["Reactome","R-HSA-399956","CRMPs in Sema3A signaling",0.03283377584435241,0.6119536497887061,16.0,6.0,304708.3125,"5362, 1808, 2534, 8829, 10371, 91584"]
["Reactome","R-HSA-2022854","Keratan sulfate biosynthesis",0.034987303693096876,0.6303545882039621,27.0,6.0,116729.92592592593,"8534, 2331, 4060, 4958, 9435, 23563"]
["Reactome","R-HSA-1222556","ROS, RNS production in phagocytes",0.03815828405095208,0.6565305849786287,33.0,6.0,83026.69696969698,"525, 528, 4688, 4842, 10312, 90423"]
["Reactome","R-HSA-166520","Signalling by NGF",0.03863506961525223,0.6565305849786287,474.0,67.0,152808.34810126582,"2675, 27237, 1846, 3708, 4205, 23263, 55615, 80824, 107, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2889, 2903, 2905, 3709, 4804, 5046, 5293, 5295, 5567, 5575, 5580, 5689, 5900, 6196, 6714, 7204, 7410, 8452, 8660, 8874, 8997, 9542, 9639, 9828, 9861, 9965, 10000, 10018, 10451, 10672, 11214, 11221, 22821, 23239, 26230, 27327, 29851, 50650, 54848, 57142, 57449, 57690, 84894, 153090, 196883"]
["Reactome","R-HSA-400206","Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)",0.038869525845173204,0.6565305849786287,124.0,20.0,138386.60483870967,"9612, 6095, 10499, 10891, 196, 1374, 1387, 2101, 2180, 2274, 4862, 5244, 7003, 9572, 9915, 23179, 25937, 26230, 29841, 80205"]
["Reactome","R-HSA-421270","Cell-cell junction organization",0.04190807770561581,0.693291759234312,63.0,14.0,389471.90476190473,"1012, 1499, 56288, 999, 1000, 1001, 1002, 1003, 1006, 5818, 10207, 23705, 24146, 50848"]
["Reactome","R-HSA-1368108","BMAL1:CLOCK,NPAS2 activates circadian gene expression",0.043815326490509655,0.6965348225917785,47.0,11.0,218111.72340425532,"6095, 10499, 10891, 25819, 1387, 2155, 4862, 8204, 9572, 80205, 150094"]
["KEGG Pathways","hsa04512","ECM-receptor interaction",0.04423612200365424,0.3437675400239103,84.0,16.0,158047.90476190476,"1277, 1291, 3655, 7058, 7148, 1289, 7143, 1278, 1282, 1293, 3695, 3910, 3918, 6382, 7057, 375790"]
["KEGG Pathways","hsa05142","Chagas disease (American trypanosomiasis)",0.04519072209553432,0.3437675400239103,104.0,17.0,148024.04807692306,"4088, 107, 718, 919, 2778, 3458, 3553, 3592, 5293, 5295, 5330, 5521, 5522, 6416, 7099, 10000, 10333"]
["KEGG Pathways","hsa05215","Prostate cancer",0.045276700393393064,0.3437675400239103,89.0,16.0,161154.0,"51176, 6934, 1499, 595, 1387, 1956, 2260, 2263, 2308, 5293, 5295, 5925, 6716, 10000, 83439, 90993"]
["Reactome","R-HSA-194138","Signaling by VEGF",0.0454465319017709,0.7119956664610774,336.0,49.0,161783.54464285713,"2675, 5829, 1499, 1846, 3708, 7424, 10458, 55615, 80824, 1003, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 3709, 4688, 4690, 5295, 5567, 5580, 5689, 6714, 7410, 8440, 8452, 8660, 8828, 8829, 8877, 9542, 9844, 9861, 9965, 10000, 10451, 11221, 22821, 26999, 153090"]
["Reactome","R-HSA-372790","Signaling by GPCR",0.046153398773908706,0.7127403439227902,1274.0,142.0,127897.59340659341,"3274, 11211, 152, 2675, 5144, 9628, 623, 27237, 50865, 1846, 2914, 3708, 5727, 5998, 6001, 6002, 6387, 7475, 8111, 8321, 23263, 50834, 80824, 219952, 107, 140, 146, 154, 155, 185, 718, 747, 1081, 1128, 1131, 1232, 1236, 1269, 1847, 1848, 1907, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2691, 2693, 2768, 2778, 2779, 2793, 2861, 2903, 2905, 3351, 3640, 3709, 3792, 4314, 5142, 5150, 5293, 5295, 5330, 5567, 5575, 5580, 5689, 5744, 5995, 6196, 6714, 6754, 7200, 7201, 7204, 7410, 7433, 7474, 7480, 7481, 7482, 8383, 8452, 8660, 8874, 8997, 9290, 9542, 9639, 9828, 9861, 9965, 10000, 10161, 10268, 10316, 10451, 10563, 10672, 10846, 10874, 11214, 11221, 11251, 11343, 22821, 23566, 26230, 26496, 26529, 26707, 50650, 50846, 51384, 53637, 53831, 54848, 56923, 57449, 79324, 80326, 85397, 122876, 132112, 151306, 153090, 196883, 219428, 219956, 221035, 256892, 285093, 346517, 347148, 390058"]
["Reactome","R-HSA-2214320","Anchoring fibril formation",0.04723437777814901,0.7172846092884513,17.0,5.0,180787.29411764705,"1277, 1278, 1282, 3918, 100422894"]
["Reactome","R-HSA-140534","Ligand-dependent caspase activation",0.0486944467264903,0.7210780398813152,17.0,4.0,129110.35294117648,"8743, 7098, 7099, 8737"]
["KEGG Pathways","hsa04145","Phagosome",0.0496220373145807,0.36330420176746586,149.0,19.0,103149.9798657718,"7058, 3689, 525, 528, 718, 1514, 3916, 4688, 4842, 4973, 7057, 7099, 8411, 9902, 10312, 10333, 81035, 90423, 653509"]
["Reactome","R-HSA-418990","Adherens junctions interactions",0.0507862465934495,0.7282693313274191,33.0,10.0,639459.4242424242,"1012, 1499, 999, 1000, 1001, 1002, 1003, 1006, 5818, 23705"]
["Reactome","R-HSA-73980","RNA Polymerase III Transcription Termination",0.05120117408037359,0.7282693313274191,23.0,4.0,100312.43478260869,"4784, 4774, 4781, 4782"]
["Reactome","R-HSA-1989781","PPARA activates gene expression",0.05267740205434815,0.7395359950746799,121.0,19.0,136792.28925619836,"6095, 10499, 10891, 196, 1374, 1387, 2101, 2180, 2274, 4862, 5244, 7003, 9572, 9915, 23179, 25937, 26230, 29841, 80205"]
["Reactome","R-HSA-500792","GPCR ligand binding",0.05435338629437664,0.7428171887237506,446.0,58.0,137382.81614349777,"3274, 11211, 152, 623, 50865, 2914, 5727, 6387, 7475, 8111, 8321, 50834, 140, 146, 154, 155, 185, 718, 1081, 1128, 1131, 1232, 1236, 1269, 1907, 2691, 2693, 2778, 2793, 2861, 3351, 3640, 3792, 5744, 5995, 6754, 7200, 7201, 7474, 7480, 7481, 7482, 9290, 10161, 10268, 10316, 10563, 10874, 11251, 23566, 50846, 51384, 53637, 56923, 80326, 122876, 151306, 347148"]
["Reactome","R-HSA-194223","HDL-mediated lipid transport",0.05588201031064354,0.7428171887237506,19.0,4.0,86081.31578947368,"348, 3069, 3931, 5567"]
["KEGG Pathways","hsa04810","Regulation of actin cytoskeleton",0.05640084545832464,0.3986956316881569,212.0,32.0,160571.74528301886,"623, 3655, 5829, 3689, 10458, 324, 1128, 1131, 1956, 2252, 2256, 2260, 2261, 2263, 2264, 2768, 3695, 4627, 4638, 5293, 5295, 5501, 7410, 8874, 9965, 10451, 10672, 26230, 26999, 54434, 85464, 93408"]
["Reactome","R-HSA-975634","Retinoid metabolism and transport",0.06157566196304121,0.752894043662322,42.0,8.0,177678.42857142858,"338, 2817, 337, 348, 4035, 5947, 6382, 375790"]
["Reactome","R-HSA-164378","PKA activation in glucagon signalling",0.06210050749440895,0.752894043662322,17.0,5.0,184763.88235294117,"107, 2778, 5567, 5575, 196883"]
["Reactome","R-HSA-5576893","Phase 2 - plateau phase",0.06319243561439176,0.752894043662322,28.0,7.0,183881.60714285713,"783, 9254, 775, 3784, 10008, 55799, 93589"]
["KEGG Pathways","hsa04115","p53 signaling pathway",0.06335160322650302,0.40128714789768266,68.0,12.0,138139.23529411765,"6477, 575, 317, 595, 894, 901, 2810, 3732, 4616, 7057, 11200, 25898"]
["Reactome","R-HSA-3928664","Ephrin signaling",0.06360313582731426,0.752894043662322,18.0,5.0,178052.11111111112,"2049, 2534, 6714, 8440, 8874"]
["KEGG Pathways","hsa05412","Arrhythmogenic right ventricular cardiomyopathy (ARVC)",0.06387348586281283,0.40128714789768266,74.0,15.0,286059.8918918919,"6262, 51176, 3655, 6934, 783, 1499, 6546, 9254, 775, 1000, 2697, 3695, 55799, 83439, 93589"]
["Reactome","R-HSA-2219528","PI3K/AKT Signaling in Cancer",0.06494937909789625,0.752894043662322,90.0,17.0,199935.01111111112,"55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 8660, 9542, 9965, 10000, 29851"]
["Reactome","R-HSA-3858494","Beta-catenin independent WNT signaling",0.06546904727498452,0.752894043662322,144.0,20.0,118511.45138888889,"51176, 6934, 1499, 3708, 8321, 1212, 1855, 2793, 3709, 4772, 4920, 5330, 5689, 7474, 7481, 9861, 23002, 27327, 57690, 83439"]
["KEGG Pathways","hsa04972","Pancreatic secretion",0.06645431235789505,0.40128714789768266,99.0,16.0,170489.15151515152,"6262, 3708, 107, 478, 486, 491, 1131, 1811, 2778, 3709, 3784, 5330, 6522, 50487, 196883, 219931"]
["KEGG Pathways","hsa05144","Malaria",0.0665549416025425,0.40128714789768266,51.0,9.0,158523.74509803922,"7058, 3689, 3458, 3553, 3592, 4035, 6382, 7057, 7099"]
["KEGG Pathways","hsa04270","Vascular smooth muscle contraction",0.06961265873249713,0.40131297367496077,114.0,20.0,222220.91228070174,"810, 3708, 107, 146, 185, 775, 2768, 2778, 3709, 4638, 5330, 5501, 5567, 5580, 10242, 10268, 10335, 10672, 50487, 196883"]
["Reactome","R-HSA-2219530","Constitutive Signaling by Aberrant PI3K in Cancer",0.06973025725315475,0.7605234268523102,65.0,14.0,237948.5076923077,"1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 5293, 5295, 8660, 9542, 9965, 29851"]
["KEGG Pathways","hsa04672","Intestinal immune network for IgA production",0.07047447342584677,0.40131297367496077,46.0,7.0,87086.04347826086,"6387, 3600, 3601, 3695, 9020, 10673, 29851"]
["Reactome","R-HSA-8875878","MET promotes cell motility",0.07198857625406603,0.7605234268523102,44.0,10.0,192170.13636363635,"1277, 1289, 1278, 2889, 3910, 3918, 6714, 64759, 255631, 100422894"]
["Reactome","R-HSA-383280","Nuclear Receptor transcription pathway",0.07298878996703581,0.7605234268523102,51.0,11.0,261318.58823529413,"5915, 6095, 2099, 2101, 2104, 2494, 5914, 7025, 7101, 8013, 9572"]
["Reactome","R-HSA-399954","Sema3A PAK dependent Axon repulsion",0.07300435666344837,0.7605234268523102,16.0,5.0,275779.8125,"5362, 2534, 8829, 10371, 91584"]
["Reactome","R-HSA-5260271","Diseases of Immune System",0.07387137818639461,0.7605234268523102,24.0,5.0,131539.91666666666,"7098, 7099, 7100, 7187, 10333"]
["Reactome","R-HSA-5602358","Diseases associated with the TLR signaling cascade",0.07387137818639461,0.7605234268523102,24.0,5.0,131539.91666666666,"7098, 7099, 7100, 7187, 10333"]
["Reactome","R-HSA-5576891","Cardiac conduction",0.0747397535461386,0.7622044677676965,141.0,24.0,183824.79432624113,"6262, 783, 3708, 6546, 9254, 30818, 478, 486, 491, 775, 1482, 2256, 3709, 3768, 3777, 3784, 4842, 10008, 25937, 30820, 54207, 55799, 80333, 93589"]
["Reactome","R-HSA-8874081","MET activates PTK2 signaling",0.07556048260509061,0.7633727261318033,33.0,8.0,188409.45454545456,"1277, 1289, 1278, 3910, 3918, 6714, 255631, 100422894"]
["KEGG Pathways","hsa04260","Cardiac muscle contraction",0.08532802758182273,0.46328522461901245,73.0,11.0,131726.02739726027,"6262, 783, 6546, 9254, 478, 486, 775, 1327, 4625, 55799, 93589"]
["KEGG Pathways","hsa05216","Thyroid cancer",0.08587726114889012,0.46328522461901245,29.0,6.0,130776.13793103448,"51176, 6934, 1499, 595, 999, 83439"]
["Reactome","R-HSA-194840","Rho GTPase cycle",0.08623523724619656,0.8117347862139892,139.0,25.0,193870.48920863308,"27237, 10395, 23263, 57522, 94134, 1124, 4650, 7204, 7410, 8874, 8997, 9639, 9828, 10451, 10672, 11214, 26230, 50650, 54848, 57449, 57636, 64411, 90627, 116985, 201176"]
["Reactome","R-HSA-4420097","VEGFA-VEGFR2 Pathway",0.0864509192683357,0.8117347862139892,328.0,46.0,159017.8536585366,"2675, 5829, 1499, 1846, 3708, 10458, 55615, 80824, 1003, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 3709, 4688, 4690, 5295, 5567, 5580, 5689, 6714, 7410, 8440, 8452, 8660, 8877, 9542, 9844, 9861, 9965, 10000, 10451, 11221, 22821, 26999, 153090"]
["Reactome","R-HSA-1638074","Keratan sulfate/keratin metabolism",0.08768889412225339,0.8117347862139892,32.0,6.0,118197.90625,"8534, 2331, 4060, 4958, 9435, 23563"]
["Reactome","R-HSA-1257604","PIP3 activates AKT signaling",0.08860749747756774,0.8117347862139892,125.0,21.0,175371.888,"55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 10000, 23239, 27327, 29851, 57690"]
["Reactome","R-HSA-186797","Signaling by PDGF",0.09109482608603289,0.8193755709905436,380.0,53.0,153788.91315789474,"2675, 1291, 7058, 1289, 1846, 3708, 55615, 80824, 107, 1282, 1293, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2889, 2903, 2905, 3709, 4690, 5293, 5295, 5567, 5575, 5580, 5689, 6714, 6778, 7057, 8440, 8452, 8660, 9542, 9861, 9965, 10000, 11221, 22821, 23239, 27327, 29851, 57690, 153090, 196883"]
["Reactome","R-HSA-1592389","Activation of Matrix Metalloproteinases",0.09359574641336443,0.8193755709905436,32.0,5.0,113272.125,"7077, 1513, 4312, 4314, 80781"]
["Reactome","R-HSA-4641262","Disassembly of the destruction complex and recruitment of AXIN to the membrane",0.09409409494421644,0.8193755709905436,31.0,6.0,118650.03225806452,"1499, 8321, 324, 1455, 1855, 10023"]
["Reactome","R-HSA-389357","CD28 dependent PI3K/Akt signaling",0.09496131917381273,0.8193755709905436,22.0,5.0,153920.5,"55615, 2534, 5295, 9020, 10000"]
["Reactome","R-HSA-5173105","O-linked glycosylation",0.096236009298318,0.8193755709905436,108.0,21.0,220492.5,"6480, 7058, 10417, 54437, 56999, 79623, 79875, 140766, 170691, 2591, 4585, 7057, 9215, 9509, 11096, 50614, 54507, 57188, 80731, 148789, 170692"]
["Reactome","R-HSA-2032785","YAP1- and WWTR1 (TAZ)-stimulated gene expression",0.09627749134019267,0.8193755709905436,29.0,7.0,200116.72413793104,"860, 10499, 1387, 1482, 7003, 25937, 80205"]
["KEGG Pathways","hsa04620","Toll-like receptor signaling pathway",0.09693073027092393,0.49676999263848515,102.0,13.0,102436.33333333333,"1513, 3553, 3592, 5293, 5295, 6416, 7098, 7099, 7100, 7187, 8737, 10000, 10333"]
["Reactome","R-HSA-397014","Muscle contraction",0.09956905946107274,0.8193755709905436,204.0,30.0,168555.26470588235,"6262, 5829, 8291, 783, 3708, 6546, 7140, 9254, 30818, 478, 486, 491, 775, 1482, 2256, 3709, 3768, 3777, 3784, 4638, 4842, 7111, 10008, 25937, 30820, 54207, 55799, 80333, 93408, 93589"]
["Reactome","R-HSA-3560783","Defective B4GALT7 causes EDS, progeroid type",0.10260245219484324,0.8193755709905436,19.0,5.0,256897.47368421053,"2817, 1462, 1634, 6382, 375790"]
["Reactome","R-HSA-3560801","Defective B3GAT3 causes JDSSDHD",0.10260245219484324,0.8193755709905436,19.0,5.0,256897.47368421053,"2817, 1462, 1634, 6382, 375790"]
["Reactome","R-HSA-4420332","Defective B3GALT6 causes EDSP2 and SEMDJL1",0.10260245219484324,0.8193755709905436,19.0,5.0,256897.47368421053,"2817, 1462, 1634, 6382, 375790"]
["Reactome","R-HSA-171052","LDL-mediated lipid transport",0.10425153804530866,0.8193755709905436,23.0,4.0,114602.08695652174,"338, 26119, 57552, 100616211"]
["Reactome","R-HSA-112409","RAF-independent MAPK1/3 activation",0.10651303038566128,0.8193755709905436,23.0,5.0,131988.08695652173,"1846, 80824, 1847, 1848, 11221"]
["Reactome","R-HSA-3769402","Deactivation of the beta-catenin transactivating complex",0.1086541917698258,0.8193755709905436,42.0,9.0,249509.30952380953,"51176, 6934, 55553, 1499, 7090, 324, 6662, 7089, 83439"]
["Reactome","R-HSA-422085","Synthesis, secretion, and deacylation of Ghrelin",0.10995364290478427,0.8193755709905436,19.0,4.0,173041.8947368421,"590, 3952, 7941, 9314"]
["Reactome","R-HSA-198203","PI3K/AKT activation",0.11024322847093508,0.8193755709905436,128.0,21.0,173956.3984375,"55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 10000, 23239, 27327, 29851, 57690"]
["Reactome","R-HSA-3214858","RMTs methylate histone arginines",0.11115757930333157,0.8193755709905436,73.0,7.0,86198.28767123287,"595, 6597, 6603, 8353, 11091, 55352, 57492"]
["Reactome","R-HSA-937041","IKK complex recruitment mediated by RIP1",0.11176565968319252,0.8193755709905436,24.0,4.0,95898.625,"7098, 7099, 8737, 11035"]
["Reactome","R-HSA-1280215","Cytokine Signaling in Immune system",0.11218092923829828,0.8193755709905436,743.0,82.0,121382.24091520862,"2675, 3394, 1846, 3689, 6095, 8808, 80824, 146433, 317649, 595, 834, 1052, 1278, 1435, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2317, 2534, 2668, 2674, 2889, 2903, 2905, 3458, 3553, 3592, 3595, 3600, 3601, 3660, 3977, 4312, 4314, 4600, 5293, 5295, 5451, 5580, 5689, 6356, 6416, 6597, 6624, 6714, 6778, 7006, 7187, 7291, 7292, 7318, 8021, 8353, 8452, 8660, 8764, 9020, 9021, 9235, 9542, 9861, 9965, 10346, 10410, 10673, 11221, 22821, 23225, 23650, 29949, 64127, 81603, 90865, 115361, 153090"]
["KEGG Pathways","hsa04660","T cell receptor signaling pathway",0.11274266557445804,0.5289112114647988,108.0,16.0,130830.99074074074,"919, 2534, 3458, 3702, 3937, 4690, 4772, 5293, 5295, 7006, 7410, 8440, 9020, 10000, 10451, 29851"]
["KEGG Pathways","hsa04930","Type II diabetes mellitus",0.11281178762877832,0.5289112114647988,48.0,9.0,172343.22916666666,"8913, 773, 775, 5293, 5295, 5580, 8660, 9021, 9370"]
["Reactome","R-HSA-5686938","Regulation of TLR by endogenous ligand",0.11307421957833783,0.8203572574777396,19.0,4.0,192590.94736842104,"338, 7099, 10333, 653509"]
["KEGG Pathways","hsa04360","Axon guidance",0.11352240636317631,0.5289112114647988,129.0,23.0,362390.4418604651,"84448, 2049, 5362, 5998, 6092, 6387, 10154, 54437, 57522, 80031, 1808, 1946, 2534, 4690, 4772, 6585, 7869, 8440, 8829, 9353, 9423, 10371, 64218"]
["Reactome","R-HSA-201681","TCF dependent signaling in response to WNT",0.11579173991737908,0.8293379049204748,226.0,26.0,116619.18584070797,"51176, 6934, 55553, 1499, 7090, 8313, 8321, 440193, 324, 1387, 1455, 1855, 5689, 6597, 6662, 7089, 7474, 8353, 8452, 9736, 9861, 10023, 23072, 50964, 51339, 83439"]
["Reactome","R-HSA-199418","Negative regulation of the PI3K/AKT network",0.12221834048369272,0.8466612790849691,94.0,17.0,200561.2340425532,"1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 10000, 23239, 29851"]
["Reactome","R-HSA-418594","G alpha (i) signalling events",0.12318504642101032,0.8466612790849691,241.0,31.0,141290.8174273859,"152, 9628, 623, 50865, 2914, 6001, 6002, 6387, 50834, 107, 140, 718, 1232, 1236, 1269, 2778, 2779, 2793, 3351, 5995, 6754, 9290, 10316, 10563, 10874, 11251, 23566, 53637, 56923, 85397, 196883"]
["KEGG Pathways","hsa05143","African trypanosomiasis",0.12570931445963363,0.5557790134095256,35.0,6.0,130692.85714285714,"3458, 3553, 3592, 3910, 5330, 8542"]
["Reactome","R-HSA-202433","Generation of second messenger molecules",0.13095125203444496,0.8466612790849691,31.0,5.0,82041.19354838709,"919, 2533, 3702, 3937, 4690"]
["Reactome","R-HSA-2029482","Regulation of actin dynamics for phagocytic cup formation",0.1323271125133665,0.8466612790849691,61.0,10.0,125379.26229508196,"10458, 919, 4627, 4650, 4690, 7410, 7456, 9844, 10451, 26999"]
["Reactome","R-HSA-449147","Signaling by Interleukins",0.1328005405858003,0.8466612790849691,520.0,62.0,135231.47115384616,"2675, 1846, 3689, 6095, 8808, 80824, 146433, 595, 834, 1052, 1278, 1435, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2889, 2903, 2905, 3553, 3592, 3595, 3600, 3601, 3977, 4312, 4314, 5293, 5295, 5451, 5689, 6356, 6416, 6597, 6624, 6714, 6778, 7006, 7291, 8353, 8452, 8660, 9021, 9235, 9542, 9861, 9965, 11221, 22821, 29949, 64127, 90865, 153090"]
["Reactome","R-HSA-6785807","Interleukin-4 and 13 signaling",0.13387279713436293,0.8466612790849691,110.0,17.0,154282.24545454545,"3689, 6095, 595, 1052, 1278, 2308, 3553, 3592, 4312, 4314, 5295, 5451, 6356, 6624, 6778, 7291, 9021"]
["KEGG Pathways","hsa04960","Aldosterone-regulated sodium reabsorption",0.13521111721164253,0.5630521793002792,42.0,8.0,181357.7857142857,"478, 486, 2810, 3290, 5293, 5295, 8660, 9351"]
["Reactome","R-HSA-1834949","Cytosolic sensors of pathogen-associated DNA ",0.13720879889312895,0.8466612790849691,68.0,8.0,70116.94117647059,"1499, 1387, 6778, 7098, 8737, 11035, 22954, 23220"]
["KEGG Pathways","hsa04720","Long-term potentiation",0.1373297998293364,0.5630521793002792,69.0,13.0,221479.27536231885,"810, 2890, 3708, 107, 775, 1387, 2903, 2905, 3709, 5330, 5501, 5567, 6196"]
["Reactome","R-HSA-5362517","Signaling by Retinoic Acid",0.13915477805260773,0.8466612790849691,43.0,8.0,140887.88372093023,"5915, 10170, 216, 1374, 1382, 5914, 9249, 157506"]
["Reactome","R-HSA-1606322","ZBP1(DAI) mediated induction of type I IFNs",0.1392234778470328,0.8466612790849691,25.0,4.0,82491.88,"7098, 8737, 11035, 23220"]
["Reactome","R-HSA-114604","GPVI-mediated activation cascade",0.13923790056759966,0.8466612790849691,56.0,9.0,122575.57142857143,"1277, 1278, 2534, 3937, 5293, 5295, 7410, 10000, 10451"]
["Reactome","R-HSA-2559584","Formation of Senescence-Associated Heterochromatin Foci (SAHF)",0.13956592450345245,0.8466612790849691,16.0,3.0,89648.5,"3005, 5925, 8091"]
["KEGG Pathways","hsa05014","Amyotrophic lateral sclerosis (ALS)",0.14059246471948614,0.5651265738724442,53.0,8.0,129011.24528301887,"79139, 2890, 317, 834, 2903, 2905, 4842, 5630"]
["Reactome","R-HSA-5218920","VEGFR2 mediated vascular permeability",0.1409796764433806,0.8466612790849691,28.0,6.0,153615.0,"1499, 55615, 1003, 7410, 10000, 10451"]
["Reactome","R-HSA-209776","Amine-derived hormones",0.14543561602835214,0.8495467512663443,18.0,4.0,174755.77777777778,"1734, 1081, 1621, 7173"]
["Reactome","R-HSA-186763","Downstream signal transduction",0.1460588149575051,0.8495467512663443,350.0,47.0,151788.7257142857,"2675, 1846, 3708, 55615, 80824, 107, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2889, 2903, 2905, 3709, 4690, 5293, 5295, 5567, 5575, 5580, 5689, 6714, 6778, 8440, 8452, 8660, 9542, 9861, 9965, 10000, 11221, 22821, 23239, 27327, 29851, 57690, 153090, 196883"]
["Reactome","R-HSA-1227986","Signaling by ERBB2",0.14993748796342682,0.8495467512663443,51.0,9.0,195515.96078431373,"1956, 2066, 2534, 5295, 5580, 6714, 9542, 10000, 55914"]
["KEGG Pathways","hsa05146","Amoebiasis",0.15124393027476174,0.5837766913331857,105.0,17.0,175792.04761904763,"1277, 1289, 3689, 107, 1278, 1282, 2778, 3458, 3553, 3592, 3910, 3918, 5293, 5295, 5330, 5567, 7099"]
["Reactome","R-HSA-5676594","TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway",0.15253507795556354,0.8495467512663443,17.0,3.0,79650.76470588235,"7187, 9020, 10673"]
["Reactome","R-HSA-1971475","A tetrasaccharide linker sequence is required for GAG synthesis",0.15311090845187225,0.8495467512663443,26.0,6.0,261631.53846153847,"2817, 1462, 1634, 6382, 64131, 375790"]
["KEGG Pathways","hsa04514","Cell adhesion molecules (CAMs)",0.15345549260600708,0.5837766913331857,131.0,19.0,208425.80916030533,"9369, 3655, 9379, 3689, 965, 999, 1000, 1001, 1002, 1003, 1462, 3695, 5818, 6382, 9019, 23705, 24146, 29851, 50848"]
["Reactome","R-HSA-2172127","DAP12 interactions",0.15444162058756575,0.8495467512663443,363.0,48.0,149556.74931129476,"2675, 1846, 3708, 55615, 80824, 107, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 3709, 3937, 5293, 5295, 5567, 5575, 5580, 5689, 6714, 7410, 8452, 8660, 9436, 9542, 9861, 9965, 10000, 10451, 11221, 22821, 23239, 27327, 29851, 57690, 153090, 196883, 284266"]
["Reactome","R-HSA-375170","CDO in myogenesis",0.15611652249016497,0.8495467512663443,29.0,7.0,336057.1724137931,"1499, 4205, 6925, 1000, 1002, 4656, 6938"]
["Reactome","R-HSA-525793","Myogenesis",0.15611652249016497,0.8495467512663443,29.0,7.0,336057.1724137931,"1499, 4205, 6925, 1000, 1002, 4656, 6938"]
["Reactome","R-HSA-212718","EGFR interacts with phospholipase C-gamma",0.15651725182368256,0.8495467512663443,35.0,8.0,203024.6,"3708, 107, 1956, 3709, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-888590","GABA synthesis, release, reuptake and degradation",0.15832190911429536,0.8495467512663443,19.0,4.0,162212.84210526315,"10815, 2572, 6529, 6539"]
["KEGG Pathways","hsa05130","Pathogenic Escherichia coli infection",0.1594902731516459,0.5944637453834074,55.0,8.0,141163.03636363638,"1499, 999, 2534, 4690, 4691, 7099, 7100, 8440"]
["Reactome","R-HSA-77387","Insulin receptor recycling",0.16085523632758275,0.8495467512663443,27.0,4.0,73483.55555555556,"525, 528, 10312, 90423"]
["Reactome","R-HSA-3371571","HSF1-dependent transactivation",0.1636054381711357,0.8495467512663443,25.0,4.0,89881.24,"3281, 57521, 1387, 26353"]
["Reactome","R-HSA-3000170","Syndecan interactions",0.16388421699709216,0.8495467512663443,29.0,6.0,152606.44827586206,"1277, 3655, 1289, 1278, 6382, 7057"]
["Reactome","R-HSA-381771","Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",0.16425094450940422,0.8495467512663443,20.0,4.0,132802.15,"6934, 1499, 3952, 5080"]
["Reactome","R-HSA-2730905","Role of LAT2/NTAL/LAB on calcium mobilization",0.16595264433917223,0.8542609930030723,134.0,21.0,171994.41044776118,"55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 10000, 23239, 27327, 29851, 57690"]
["KEGG Pathways","hsa04144","Endocytosis",0.1664599269265394,0.5986716670165014,201.0,26.0,146092.3432835821,"4088, 116987, 10015, 23362, 56288, 154, 155, 1212, 1956, 2060, 2066, 2261, 2263, 2264, 5867, 6714, 8411, 9525, 9815, 9922, 23550, 26119, 64411, 84249, 116983, 116985"]
["Reactome","R-HSA-5617472","Activation of anterior HOX genes in hindbrain development during early embryogenesis",0.17276047240162723,0.8593188296301203,118.0,10.0,70945.28813559322,"5915, 9935, 4211, 1387, 3211, 5080, 5087, 5914, 8353, 11091"]
["Reactome","R-HSA-5619507","Activation of HOX genes during differentiation",0.17276047240162723,0.8593188296301203,118.0,10.0,70945.28813559322,"5915, 9935, 4211, 1387, 3211, 5080, 5087, 5914, 8353, 11091"]
["KEGG Pathways","hsa04742","Taste transduction",0.17495340776132723,0.5987069443078807,51.0,7.0,129011.58823529411,"2914, 50834, 773, 2778, 5330, 5567, 196883"]
["Reactome","R-HSA-170834","Signaling by TGF-beta Receptor Complex",0.17514909969904408,0.8593188296301203,74.0,11.0,125592.24324324324,"4088, 9612, 56288, 4089, 5501, 6497, 7027, 8812, 25937, 50848, 56937"]
["Reactome","R-HSA-5689896","Ovarian tumor domain proteases",0.17872767174555132,0.8593188296301203,37.0,6.0,120502.27027027027,"324, 2099, 7187, 8737, 23252, 64127"]
["Reactome","R-HSA-2187338","Visual phototransduction",0.17981396606197608,0.8593188296301203,96.0,13.0,128011.29166666667,"338, 2817, 10170, 337, 348, 2779, 4035, 5947, 5957, 6382, 9249, 157506, 375790"]
["Reactome","R-HSA-210991","Basigin interactions",0.18157176577534612,0.8593188296301203,25.0,4.0,82432.8,"3655, 4312, 9056, 9123"]
["Reactome","R-HSA-177929","Signaling by EGFR",0.18204738317950403,0.8593188296301203,362.0,49.0,162694.4640883978,"2675, 5829, 1846, 3708, 55615, 80824, 107, 1847, 1848, 1956, 2060, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 3709, 5293, 5295, 5567, 5575, 5580, 5689, 5774, 6714, 8452, 8660, 8874, 9542, 9861, 9965, 10000, 10252, 11221, 22821, 23239, 27327, 29851, 55824, 57690, 153090, 196883"]
["Reactome","R-HSA-166663","Initial triggering of complement",0.18437442130308618,0.8593188296301203,22.0,3.0,94396.09090909091,"718, 1675, 5648"]
["Reactome","R-HSA-109704","PI3K Cascade",0.1859195040882469,0.8593188296301203,79.0,12.0,137692.7088607595,"51422, 57521, 2252, 2260, 2261, 2263, 2264, 5295, 8660, 9965, 55437, 64121"]
["Reactome","R-HSA-5213460","RIPK1-mediated regulated necrosis",0.18602900157319294,0.8593188296301203,20.0,3.0,65197.15,"8743, 8737, 11035"]
["Reactome","R-HSA-5218859","Regulated Necrosis",0.18602900157319294,0.8593188296301203,20.0,3.0,65197.15,"8743, 8737, 11035"]
["KEGG Pathways","hsa00051","Fructose and mannose metabolism",0.18884311332608072,0.6137930762997134,36.0,5.0,84030.91666666667,"29926, 229, 2762, 5214, 9108"]
["Reactome","R-HSA-5357801","Programmed Cell Death",0.19222836421111664,0.8593188296301203,173.0,21.0,122557.95953757226,"1499, 8743, 90427, 317, 324, 999, 1612, 2810, 3005, 4976, 5580, 5689, 7027, 7098, 7099, 8737, 9414, 9861, 10000, 10018, 11035"]
["Reactome","R-HSA-163210","Formation of ATP by chemiosmotic coupling",0.1946786004378774,0.8593188296301203,16.0,2.0,51448.3125,"27109, 517"]
["Reactome","R-HSA-6811558","PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",0.1977110895731761,0.8593188296301203,87.0,15.0,201594.8735632184,"1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 5293, 5295, 6714, 8660, 9542, 9965, 29851"]
["Reactome","R-HSA-112043","PLC beta mediated events",0.201067946340114,0.8593188296301203,46.0,9.0,223525.47826086957,"3708, 107, 2779, 3709, 5330, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-389356","CD28 co-stimulation",0.2012154062108004,0.8593188296301203,33.0,6.0,140901.39393939395,"55615, 2534, 5295, 6714, 9020, 10000"]
["Reactome","R-HSA-5357769","Caspase activation via extrinsic apoptotic signalling pathway",0.2034197541659405,0.8593188296301203,28.0,5.0,184142.75,"8743, 1612, 7098, 7099, 8737"]
["Reactome","R-HSA-388396","GPCR downstream signaling",0.20470633547043957,0.8593188296301203,952.0,98.0,118254.52205882352,"3274, 152, 5144, 9628, 623, 27237, 50865, 2914, 3708, 5998, 6001, 6002, 6387, 8111, 23263, 50834, 219952, 107, 140, 146, 154, 155, 185, 718, 747, 1081, 1128, 1131, 1232, 1236, 1269, 1907, 2691, 2693, 2768, 2778, 2779, 2793, 3351, 3640, 3709, 5142, 5150, 5293, 5295, 5330, 5580, 5744, 5995, 6754, 7200, 7201, 7204, 7410, 7433, 8383, 8874, 8997, 9290, 9639, 9828, 10000, 10161, 10268, 10316, 10451, 10563, 10672, 10846, 10874, 11214, 11251, 11343, 23566, 26230, 26496, 26529, 26707, 50650, 53637, 53831, 54848, 56923, 57449, 79324, 85397, 122876, 132112, 151306, 196883, 219428, 219956, 221035, 256892, 285093, 346517, 347148, 390058"]
["KEGG Pathways","hsa05110","Vibrio cholerae infection",0.20531786934332147,0.6475409725443215,53.0,8.0,128644.2641509434,"525, 528, 2778, 3784, 5567, 9414, 10312, 90423"]
["Reactome","R-HSA-6806667","Metabolism of fat-soluble vitamins",0.2139387558667319,0.8593188296301203,50.0,8.0,171997.44,"338, 2817, 337, 348, 4035, 5947, 6382, 375790"]
["KEGG Pathways","hsa04010","MAPK signaling pathway",0.21791988875971008,0.676872381753645,267.0,35.0,161743.3670411985,"4908, 783, 1846, 8912, 8913, 9254, 80824, 627, 773, 775, 1847, 1848, 1956, 2252, 2256, 2260, 2261, 2263, 2264, 2317, 2768, 3553, 4214, 4216, 4616, 5567, 6196, 6416, 9020, 9965, 10000, 11221, 50487, 55799, 93589"]
["Reactome","R-HSA-3000171","Non-integrin membrane-ECM interactions",0.2194062708116524,0.8593188296301203,64.0,11.0,228317.515625,"1277, 3655, 1289, 1278, 1282, 3910, 3918, 6382, 7057, 375790, 100422894"]
["Reactome","R-HSA-168249","Innate Immune System",0.22102287566711828,0.8593188296301203,1250.0,125.0,110355.1696,"2675, 338, 1499, 1846, 3689, 3708, 4205, 7077, 8972, 10458, 23250, 55615, 80824, 121260, 1, 107, 272, 317, 411, 525, 528, 718, 834, 919, 965, 1113, 1387, 1513, 1514, 1675, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 3553, 3660, 3702, 3709, 3916, 3937, 3958, 4214, 4585, 4627, 4650, 4688, 4690, 4772, 4842, 4973, 5293, 5295, 5328, 5567, 5575, 5580, 5648, 5689, 6196, 6286, 6416, 6518, 6714, 6778, 7006, 7098, 7099, 7100, 7187, 7318, 7410, 7456, 8411, 8452, 8660, 8737, 9020, 9051, 9145, 9436, 9542, 9844, 9861, 9965, 10000, 10312, 10333, 10451, 10493, 10628, 10875, 11035, 11221, 22821, 22954, 23218, 23220, 23239, 26999, 27327, 29851, 53831, 57020, 57690, 64127, 79895, 84766, 90423, 150372, 153090, 196883, 284266, 653509, 100616211"]
["Reactome","R-HSA-2173796","SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",0.22160688848334217,0.8593188296301203,33.0,5.0,96717.69696969698,"4088, 4089, 7027, 8812, 25937"]
["Reactome","R-HSA-2424491","DAP12 signaling",0.22182397632546094,0.8593188296301203,352.0,46.0,152431.44886363635,"2675, 1846, 3708, 55615, 80824, 107, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 3709, 3937, 5293, 5295, 5567, 5575, 5580, 5689, 6714, 7410, 8452, 8660, 9542, 9861, 9965, 10000, 10451, 11221, 22821, 23239, 27327, 29851, 57690, 153090, 196883"]
["Reactome","R-HSA-6783589","Interleukin-6 family signaling",0.2230470786838747,0.8593188296301203,27.0,4.0,81261.14814814815,"3592, 3595, 3977, 9021"]
["KEGG Pathways","hsa05221","Acute myeloid leukemia",0.22457017559291143,0.6820338371992567,57.0,9.0,152619.56140350876,"51176, 6934, 595, 5293, 5295, 5914, 7704, 10000, 83439"]
["Reactome","R-HSA-8876384","Listeria monocytogenes entry into host cells",0.22464126402657458,0.8593188296301203,20.0,4.0,147208.35,"1499, 999, 2060, 6714"]
["KEGG Pathways","hsa05120","Epithelial cell signaling in Helicobacter pylori infection",0.22623561429048517,0.6820338371992567,68.0,9.0,99648.54411764706,"525, 528, 1956, 6416, 6714, 9020, 10312, 50848, 90423"]
["Reactome","R-HSA-917977","Transferrin endocytosis and recycling",0.22679222035979332,0.8593188296301203,30.0,4.0,70901.13333333333,"525, 528, 10312, 90423"]
["Reactome","R-HSA-163615","PKA activation",0.2289397066914659,0.8593188296301203,18.0,4.0,172361.16666666666,"107, 5567, 5575, 196883"]
["Reactome","R-HSA-202733","Cell surface interactions at the vascular wall",0.23306609254096045,0.8661182887319608,135.0,17.0,136192.77777777778,"1277, 338, 3655, 2817, 3689, 965, 1278, 2534, 4312, 4973, 5295, 6382, 6714, 9056, 9123, 50848, 51744"]
["Reactome","R-HSA-168898","Toll-Like Receptors Cascades",0.23318299816121504,0.8661182887319608,155.0,20.0,134200.06451612903,"338, 1846, 3689, 4205, 1513, 1514, 1848, 4214, 6196, 6416, 7098, 7099, 7100, 7187, 8411, 8737, 10333, 11035, 64127, 653509"]
["Reactome","R-HSA-1489509","DAG and IP3 signaling",0.23549000255517596,0.8661182887319608,33.0,7.0,197396.84848484848,"3708, 107, 3709, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-76009","Platelet Aggregation (Plug Formation)",0.2400259124618676,0.8661182887319608,37.0,6.0,122577.37837837837,"152, 1277, 11069, 1278, 6714, 7066"]
["Reactome","R-HSA-373076","Class A/1 (Rhodopsin-like receptors)",0.24099863509342712,0.8661182887319608,316.0,40.0,143172.2594936709,"3274, 152, 623, 50865, 6387, 8111, 140, 146, 154, 155, 185, 718, 1081, 1128, 1131, 1232, 1236, 1269, 1907, 2693, 2861, 3351, 3640, 3792, 5995, 6754, 7200, 7201, 9290, 10161, 10316, 10563, 10874, 11251, 23566, 53637, 56923, 122876, 151306, 347148"]
["Reactome","R-HSA-416700","Other semaphorin interactions",0.24250833891799106,0.8661182887319608,19.0,5.0,349315.36842105264,"5362, 10154, 80031, 64218, 91584"]
["KEGG Pathways","hsa05414","Dilated cardiomyopathy",0.24419486871071142,0.7127317528110876,90.0,14.0,218753.6222222222,"6262, 3655, 783, 6546, 9254, 107, 775, 2778, 3695, 4625, 5567, 55799, 93589, 196883"]
["Reactome","R-HSA-163841","Gamma carboxylation, hypusine formation and arylsulfatase activation",0.24470250601391522,0.8661182887319608,38.0,5.0,141704.7894736842,"411, 2155, 22901, 51611, 340075"]
["Reactome","R-HSA-74158","RNA Polymerase III Transcription",0.24504926980274372,0.8661182887319608,41.0,5.0,90088.87804878049,"4784, 4774, 4781, 4782, 5451"]
["Reactome","R-HSA-749476","RNA Polymerase III Abortive And Retractive Initiation",0.24504926980274372,0.8661182887319608,41.0,5.0,90088.87804878049,"4784, 4774, 4781, 4782, 5451"]
["KEGG Pathways","hsa04730","Long-term depression",0.24687739881546683,0.7127317528110876,69.0,12.0,251200.08695652173,"2890, 3708, 773, 2768, 2778, 2895, 3709, 4842, 5330, 10672, 10842, 50487"]
["KEGG Pathways","hsa04670","Leukocyte transendothelial migration",0.2470691766809276,0.7127317528110876,116.0,16.0,162723.1551724138,"5829, 1499, 3689, 6387, 11069, 1003, 3702, 4688, 5293, 5295, 7410, 10451, 24146, 50848, 83593, 93408"]
["Reactome","R-HSA-388841","Costimulation by the CD28 family",0.24933621584626944,0.8661182887319608,67.0,9.0,105345.89552238806,"55615, 919, 2534, 5295, 6714, 8764, 9020, 10000, 29851"]
["Reactome","R-HSA-112040","G-protein mediated events",0.25155170499426643,0.8661182887319608,47.0,9.0,227527.085106383,"3708, 107, 2779, 3709, 5330, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-6788467","IL-6-type cytokine receptor ligand interactions",0.2548649457638448,0.8661182887319608,20.0,3.0,80118.65,"3592, 3595, 3977"]
["Reactome","R-HSA-373752","Netrin-1 signaling",0.25820709168087086,0.8661182887319608,42.0,10.0,393377.0238095238,"84448, 6477, 2534, 4690, 6585, 6714, 7204, 9353, 9423, 56963"]
["KEGG Pathways","hsa05218","Melanoma",0.26104319697937467,0.7188076000566443,71.0,12.0,195467.15492957746,"4286, 595, 999, 1956, 2252, 2256, 2260, 5293, 5295, 5925, 9965, 10000"]
["Reactome","R-HSA-376176","Signaling by Robo receptor",0.26161037344860005,0.8661182887319608,31.0,7.0,348483.93548387097,"2817, 6092, 57522, 4690, 8440, 9353, 10486"]
["Reactome","R-HSA-2029485","Role of phospholipids in phagocytosis",0.2621421303390098,0.8661182887319608,26.0,5.0,175010.57692307694,"3708, 919, 3709, 5295, 5580"]
["Reactome","R-HSA-975576","N-glycan antennae elongation in the medial/trans-Golgi",0.2652036573268076,0.8661182887319608,26.0,5.0,178437.73076923078,"6480, 1081, 11320, 64377, 338596"]
["Reactome","R-HSA-1963642","PI3K events in ERBB2 signaling",0.26692328851222913,0.8676990145829918,16.0,4.0,394094.8125,"1956, 2066, 5295, 9542"]
["Reactome","R-HSA-400042","Adrenaline,noradrenaline inhibits insulin secretion",0.2699444694262015,0.8694868882557586,28.0,5.0,147653.67857142858,"152, 783, 9254, 775, 2793"]
["Reactome","R-HSA-381676","Glucagon-like Peptide-1 (GLP1) regulates insulin secretion",0.27156303480019656,0.8694868882557586,42.0,7.0,139700.38095238095,"3708, 11069, 2778, 2793, 3709, 5567, 5575"]
["Reactome","R-HSA-8876198","RAB GEFs exchange GTP for GDP on RABs",0.27237176489449066,0.8694868882557586,89.0,12.0,120287.73033707865,"54453, 83696, 5866, 6764, 10000, 25782, 27147, 51112, 51762, 79890, 81846, 117177"]
["Reactome","R-HSA-446353","Cell-extracellular matrix interactions",0.2731263838779569,0.8694868882557586,17.0,3.0,100431.70588235294,"5829, 29780, 54751"]
["Reactome","R-HSA-3000157","Laminin interactions",0.27527966600379766,0.8694868882557586,33.0,6.0,140799.51515151514,"3655, 1282, 3910, 3918, 80781, 100422894"]
["Reactome","R-HSA-418555","G alpha (s) signalling events",0.27533325519545654,0.8694868882557586,143.0,20.0,154835.06993006993,"3274, 5144, 107, 154, 155, 1081, 2691, 2778, 2793, 3640, 5142, 5150, 5744, 7433, 10268, 10846, 53831, 122876, 151306, 196883"]
["Reactome","R-HSA-109581","Apoptosis",0.27769078184894175,0.8694868882557586,170.0,20.0,124002.45294117647,"1499, 8743, 90427, 317, 324, 999, 1612, 2810, 3005, 4976, 5580, 5689, 7027, 7098, 7099, 8737, 9414, 9861, 10000, 10018"]
["Reactome","R-HSA-622312","Inflammasomes",0.2781875573827712,0.8694868882557586,17.0,3.0,114265.88235294117,"834, 9051, 10628"]
["KEGG Pathways","hsa04380","Osteoclast differentiation",0.28004982123854755,0.7317470827705681,127.0,16.0,129821.68503937007,"4286, 1435, 1513, 2274, 2534, 3458, 3553, 3937, 4688, 4772, 5293, 5295, 7006, 9020, 9021, 10000"]
["Reactome","R-HSA-936964","Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon",0.2807803528577048,0.8694881317062018,18.0,3.0,133929.11111111112,"7098, 7099, 7187"]
["Reactome","R-HSA-2173793","Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",0.281517896482119,0.8694881317062018,45.0,7.0,122202.6888888889,"4088, 9612, 4089, 6497, 7027, 8812, 25937"]
["KEGG Pathways","hsa00071","Fatty acid degradation",0.2828605754211338,0.7317470827705681,43.0,5.0,68056.83720930232,"125, 1374, 2180, 8310, 23305"]
["Reactome","R-HSA-6806834","Signaling by MET",0.285354220916275,0.8738467784999809,82.0,13.0,168338.84146341463,"1277, 1289, 1278, 2060, 2889, 3910, 3918, 5295, 5867, 6714, 64759, 255631, 100422894"]
["Reactome","R-HSA-4641258","Degradation of DVL",0.2946186562541915,0.8877582377167847,57.0,6.0,69559.78947368421,"1855, 5689, 8452, 9861, 23072, 51339"]
["Reactome","R-HSA-1912408","Pre-NOTCH Transcription and Translation",0.298600799508256,0.8877582377167847,30.0,5.0,115624.0,"595, 1387, 7027, 27327, 57690"]
["Reactome","R-HSA-3134975","Regulation of innate immune responses to cytosolic DNA",0.2999302028268253,0.8877582377167847,15.0,2.0,57934.333333333336,"22954, 23220"]
["Reactome","R-HSA-8863795","Downregulation of ERBB2 signaling",0.3002207132999319,0.8877582377167847,30.0,5.0,215450.3,"1956, 2066, 9542, 10000, 55914"]
["Reactome","R-HSA-912631","Regulation of signaling by CBL",0.30030268005583904,0.8877582377167847,22.0,4.0,153825.0909090909,"2534, 2889, 5293, 5295"]
["Reactome","R-HSA-157118","Signaling by NOTCH",0.3011973739810242,0.8877582377167847,111.0,16.0,179373.0990990991,"9612, 9759, 28514, 7090, 23462, 595, 1387, 3714, 3955, 7027, 7089, 23220, 23493, 27327, 57690, 388585"]
["Reactome","R-HSA-198753","ERK/MAPK targets",0.30221557028656504,0.8877582377167847,22.0,4.0,163393.72727272726,"1846, 4205, 1848, 6196"]
["Reactome","R-HSA-111931","PKA-mediated phosphorylation of CREB",0.3039465043462442,0.8901183719525737,19.0,4.0,176104.1052631579,"107, 5567, 5575, 196883"]
["KEGG Pathways","hsa04650","Natural killer cell mediated cytotoxicity",0.3045924340975412,0.7317470827705681,130.0,14.0,92272.13846153846,"3689, 8743, 919, 2534, 3458, 3937, 4772, 5293, 5295, 7410, 9436, 10451, 10870, 51744"]
["KEGG Pathways","hsa04530","Tight junction",0.30636400650874923,0.7317470827705681,132.0,18.0,166270.31818181818,"1499, 56288, 2037, 4625, 4627, 5521, 5522, 5580, 6714, 9223, 9414, 10000, 10207, 22989, 24146, 50848, 93408, 93643"]
["Reactome","R-HSA-167021","PLC-gamma1 signalling",0.3071651973713944,0.8911152022672992,35.0,7.0,195201.62857142856,"3708, 107, 3709, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-114452","Activation of BH3-only proteins",0.30843592767130046,0.8914952882691866,31.0,5.0,120084.45161290323,"90427, 2810, 7027, 10000, 10018"]
["Reactome","R-HSA-1834941","STING mediated induction of host immune responses",0.3102148103637473,0.8942458933418956,16.0,2.0,49227.9375,"6778, 23220"]
["Reactome","R-HSA-1810476","RIP-mediated NFkB activation via ZBP1",0.3117351340349016,0.8962385103503421,21.0,3.0,88423.76190476191,"7098, 8737, 11035"]
["Reactome","R-HSA-3371568","Attenuation phase",0.3140015279256536,0.8987261693000432,15.0,2.0,61699.4,"3281, 1387"]
["Reactome","R-HSA-1793185","Chondroitin sulfate/dermatan sulfate metabolism",0.31722938636908204,0.8999192639867082,50.0,9.0,234508.3,"2817, 411, 1462, 1634, 6382, 10090, 64131, 92126, 375790"]
["KEGG Pathways","hsa04910","Insulin signaling pathway",0.31906915615677306,0.7317470827705681,137.0,17.0,142286.82481751824,"810, 5257, 10891, 51422, 57521, 2308, 2889, 3991, 5293, 5295, 5501, 5567, 5575, 8660, 9021, 10000, 57818"]
["Reactome","R-HSA-418457","cGMP effects",0.32134027372698365,0.8999192639867082,18.0,5.0,339456.77777777775,"5152, 3708, 10242, 10335, 10846"]
["Reactome","R-HSA-400508","Incretin synthesis, secretion, and inactivation",0.322923507213304,0.9020163082624848,23.0,4.0,167602.73913043478,"6934, 1499, 3952, 5080"]
["Reactome","R-HSA-983712","Ion channel transport",0.32393531258053904,0.9025104971638214,211.0,28.0,143840.57819905214,"6262, 23250, 55107, 57101, 41, 478, 486, 491, 525, 528, 2562, 2741, 7439, 8737, 10079, 10312, 11035, 23120, 28962, 53373, 54795, 55515, 57719, 65125, 79895, 90423, 219931, 344905"]
["Reactome","R-HSA-983695","Antigen activates B Cell Receptor (BCR) leading to generation of second messengers",0.3275132204893069,0.9045326487504024,37.0,6.0,164387.8918918919,"3708, 2534, 3709, 4690, 5293, 5295"]
["KEGG Pathways","hsa05010","Alzheimer's disease",0.32769439817313284,0.7382126552251893,158.0,16.0,102196.04430379746,"810, 3708, 317, 348, 517, 775, 1327, 2903, 2905, 3553, 3709, 4035, 4842, 5330, 6390, 56901"]
["KEGG Pathways","hsa04623","Cytosolic DNA-sensing pathway",0.33179247550266966,0.7393201899787748,55.0,5.0,50032.87272727273,"834, 3553, 8737, 11035, 90865"]
["Reactome","R-HSA-157858","Gap junction trafficking and regulation",0.3319264843565324,0.9045326487504024,48.0,6.0,95243.4375,"1212, 2697, 2700, 2702, 2703, 6714"]
["Reactome","R-HSA-445144","Signal transduction by L1",0.3325680071269525,0.9045326487504024,21.0,4.0,157451.38095238095,"1956, 2260, 7410, 8829"]
["Reactome","R-HSA-8855121","VLDL interactions",0.3335757706716671,0.9045326487504024,22.0,4.0,222826.54545454544,"338, 29116, 2534, 5034"]
["Reactome","R-HSA-352230","Amino acid transport across the plasma membrane",0.3348695078753768,0.9045326487504024,31.0,5.0,139292.25806451612,"6509, 6510, 6539, 9056, 124935"]
["Reactome","R-HSA-2453902","The canonical retinoid cycle in rods (twilight vision)",0.3385470302649371,0.9045326487504024,22.0,3.0,74860.72727272728,"10170, 5947, 157506"]
["Reactome","R-HSA-186712","Regulation of beta-cell development",0.3394949960974998,0.9045326487504024,32.0,6.0,195360.34375,"3642, 2308, 2494, 5080, 6928, 10000"]
["Reactome","R-HSA-180024","DARPP-32 events",0.3412244720520833,0.9045326487504024,25.0,4.0,179717.84,"5144, 5142, 5567, 5575"]
["Reactome","R-HSA-380972","Energy dependent regulation of mTOR by LKB1-AMPK",0.3434745105051247,0.9055998679415604,28.0,4.0,101256.32142857143,"51422, 57521, 55437, 64121"]
["Reactome","R-HSA-391160","Signal regulatory protein (SIRP) family interactions",0.348274557809455,0.9090328958135842,16.0,3.0,126226.3125,"2533, 6714, 653509"]
["Reactome","R-HSA-451326","Activation of Kainate Receptors upon glutamate binding",0.35738955420349294,0.9090328958135842,31.0,5.0,196665.0,"2793, 2898, 2900, 2901, 5330"]
["Reactome","R-HSA-182971","EGFR downregulation",0.3599131169363682,0.9090328958135842,25.0,5.0,268836.36,"1956, 2060, 5774, 8874, 10252"]
["Reactome","R-HSA-195253","Degradation of beta-catenin by the destruction complex",0.36225565466712467,0.9094651320424367,82.0,10.0,131789.73170731709,"51176, 6934, 1499, 7090, 324, 5689, 7089, 9861, 10023, 83439"]
["Reactome","R-HSA-416476","G alpha (q) signalling events",0.36452628342146237,0.9100529154240204,189.0,27.0,174352.84656084655,"623, 3708, 5998, 8111, 146, 185, 747, 1128, 1131, 1907, 2693, 2793, 3709, 5295, 5330, 5580, 7200, 7201, 7204, 8997, 10161, 10316, 10874, 11343, 23566, 56923, 347148"]
["KEGG Pathways","hsa05212","Pancreatic cancer",0.3675241694282372,0.7695948410902962,70.0,10.0,150152.3142857143,"4088, 7424, 595, 1956, 4089, 5293, 5295, 5900, 5925, 10000"]
["Reactome","R-HSA-2454202","Fc epsilon receptor (FCERI) signaling",0.3729751524127261,0.9231554734010353,370.0,46.0,148734.03783783785,"2675, 1846, 3708, 55615, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 3702, 3709, 3937, 4214, 4772, 5293, 5295, 5689, 6416, 6714, 7006, 7410, 8452, 8660, 9542, 9861, 9965, 10000, 10451, 11221, 22821, 23239, 27327, 29851, 57690, 153090"]
["KEGG Pathways","hsa00260","Glycine, serine and threonine metabolism",0.3739613700105201,0.7695948410902962,32.0,4.0,101007.71875,"1610, 1757, 2731, 6472"]
["Reactome","R-HSA-190236","Signaling by FGFR",0.3784460932703283,0.9231554734010353,88.0,11.0,152947.5909090909,"23769, 2252, 2260, 2261, 2263, 2264, 2591, 5295, 6714, 9965, 53834"]
["Reactome","R-HSA-2122947","NOTCH1 Intracellular Domain Regulates Transcription",0.3809887218921254,0.9231554734010353,48.0,8.0,222151.16666666666,"9612, 9759, 7090, 23462, 1387, 7089, 23493, 388585"]
["Reactome","R-HSA-881907","Gastrin-CREB signalling pathway via PKC and MAPK",0.38275646021230425,0.9231554734010353,438.0,56.0,164309.2214611872,"2675, 623, 1846, 3708, 5998, 8111, 80824, 146, 185, 747, 1128, 1131, 1847, 1848, 1907, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2693, 2793, 2903, 2905, 3709, 4314, 5295, 5330, 5580, 5689, 6196, 6714, 7200, 7201, 7204, 8452, 8660, 8997, 9542, 9861, 9965, 10161, 10316, 10874, 11221, 11343, 22821, 23566, 56923, 153090, 347148"]
["Reactome","R-HSA-456926","Thrombin signalling through proteinase activated receptors (PARs)",0.38425660921563015,0.9231554734010353,32.0,4.0,82652.25,"2768, 2793, 6714, 10672"]
["Reactome","R-HSA-1980143","Signaling by NOTCH1",0.3844805129708735,0.9231554734010353,73.0,11.0,192795.86301369863,"9612, 9759, 28514, 7090, 23462, 1387, 3714, 7089, 23220, 23493, 388585"]
["Reactome","R-HSA-375165","NCAM signaling for neurite out-growth",0.3850322661478373,0.9231554734010353,280.0,36.0,157991.60357142857,"2675, 1291, 783, 1289, 1846, 8912, 8913, 80824, 775, 1282, 1293, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090, 375790"]
["Reactome","R-HSA-163359","Glucagon signaling in metabolic regulation",0.38675594464718177,0.9244746950112598,33.0,5.0,128324.30303030302,"107, 2778, 5567, 5575, 196883"]
["Reactome","R-HSA-109582","Hemostasis",0.38740706460693863,0.9244746950112598,634.0,70.0,138547.49369085173,"5152, 152, 1277, 338, 3655, 2817, 3689, 3708, 6546, 7123, 7424, 10019, 11069, 23348, 1, 491, 547, 747, 832, 965, 1278, 1387, 1675, 2152, 2155, 2534, 2768, 2778, 2793, 3660, 3709, 3937, 4312, 4602, 4842, 4973, 5051, 5293, 5295, 5328, 5567, 5575, 5580, 5890, 6281, 6382, 6714, 7057, 7066, 7078, 7410, 8353, 9056, 9123, 9732, 10000, 10242, 10335, 10451, 10672, 10846, 11343, 26153, 50848, 51097, 51744, 54863, 91768, 140628, 221458"]
["Reactome","R-HSA-109606","Intrinsic Pathway for Apoptosis",0.3939514548439533,0.9299157826000835,44.0,6.0,106356.36363636363,"90427, 317, 2810, 7027, 10000, 10018"]
["KEGG Pathways","hsa05223","Non-small cell lung cancer",0.3959754251142627,0.7723969148675671,54.0,8.0,164862.87037037036,"5915, 595, 1956, 5293, 5295, 5925, 10000, 83593"]
["Reactome","R-HSA-392154","Nitric oxide stimulates guanylate cyclase",0.39681399925624133,0.9299157826000835,24.0,6.0,323804.25,"5152, 3708, 4842, 10242, 10335, 10846"]
["KEGG Pathways","hsa04630","Jak-STAT signaling pathway",0.3979943789815829,0.7723969148675671,155.0,18.0,235974.05806451614,"595, 894, 1387, 3458, 3592, 3595, 3600, 3601, 3952, 3977, 5293, 5295, 6778, 7173, 9021, 10000, 10252, 29949"]
["KEGG Pathways","hsa04664","Fc epsilon RI signaling pathway",0.39869848488030546,0.7723969148675671,78.0,10.0,146190.62820512822,"2534, 3937, 5293, 5295, 5580, 6416, 7410, 10000, 10451, 50487"]
["KEGG Pathways","hsa04060","Cytokine-cytokine receptor interaction",0.3990821614511485,0.7723969148675671,264.0,28.0,117372.52272727272,"650, 6387, 7424, 8743, 90, 655, 1232, 1236, 1435, 1956, 3458, 3553, 3592, 3595, 3600, 3601, 3952, 3977, 4804, 6356, 7173, 7292, 8200, 8764, 10563, 10673, 29949, 83729"]
["Reactome","R-HSA-8848021","Signaling by PTK6",0.4033027879636795,0.9333465201376827,67.0,10.0,246708.1343283582,"5829, 595, 1956, 2066, 9021, 9542, 9844, 22821, 116985, 153090"]
["Reactome","R-HSA-392517","Rap1 signalling",0.4043450810043628,0.9333465201376827,16.0,3.0,147241.625,"11069, 5567, 5909"]
["KEGG Pathways","hsa04210","Apoptosis",0.4069213014912061,0.7723969148675671,87.0,10.0,113069.62068965517,"8743, 317, 3553, 5293, 5295, 5567, 5575, 8737, 9020, 10000"]
["Reactome","R-HSA-8866910","TFAP2 (AP-2) family regulates transcription of growth factors and their receptors",0.41054570716875183,0.942250338533802,15.0,3.0,193113.46666666667,"1081, 1956, 2099"]
["KEGG Pathways","hsa04062","Chemokine signaling pathway",0.4205740243362635,0.7837970453539456,188.0,21.0,134087.414893617,"5829, 6387, 56288, 107, 1232, 1236, 2793, 3702, 5293, 5295, 5330, 5567, 5580, 6356, 7410, 9844, 10000, 10451, 10563, 26230, 196883"]
["Reactome","R-HSA-190861","Gap junction assembly",0.4223019937332134,0.9630980068050711,35.0,4.0,79180.62857142858,"2697, 2700, 2702, 2703"]
["Reactome","R-HSA-264642","Acetylcholine Neurotransmitter Release Cycle",0.42638157312520275,0.968316135605765,17.0,3.0,206433.88235294117,"10815, 8499, 60482"]
["Reactome","R-HSA-918233","TRAF3-dependent IRF activation pathway",0.4286455238886387,0.9693845425180301,16.0,2.0,64438.9375,"1387, 7187"]
["Reactome","R-HSA-196299","Beta-catenin phosphorylation cascade",0.43048901527732575,0.9703328278496669,17.0,3.0,133881.0,"1499, 324, 10023"]
["Reactome","R-HSA-420029","Tight junction interactions",0.4469480680390236,0.9726910685202514,30.0,4.0,114485.63333333333,"56288, 10207, 24146, 50848"]
["KEGG Pathways","hsa05222","Small cell lung cancer",0.44829256416470026,0.8205354969086032,85.0,12.0,160193.11764705883,"5915, 3655, 317, 595, 1282, 3910, 3918, 5293, 5295, 5925, 7187, 10000"]
["Reactome","R-HSA-111885","Opioid Signalling",0.4501717871913324,0.9726910685202514,83.0,12.0,196350.07228915664,"5144, 3708, 107, 2779, 2793, 3709, 5142, 5330, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-3214842","HDMs demethylate histones",0.45351522097281916,0.9726910685202514,49.0,5.0,91693.08163265306,"8353, 22992, 23030, 84159, 84678"]
["Reactome","R-HSA-5578775","Ion homeostasis",0.45659465590204124,0.9726910685202514,55.0,8.0,157359.85454545455,"6262, 3708, 6546, 478, 486, 491, 3709, 4842"]
["Reactome","R-HSA-111933","Calmodulin induced events",0.456754784824891,0.9726910685202514,27.0,5.0,190293.33333333334,"107, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-111997","CaM pathway",0.456754784824891,0.9726910685202514,27.0,5.0,190293.33333333334,"107, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-198725","Nuclear Events (kinase and transcription factor activation)",0.4633985296920239,0.9726910685202514,25.0,4.0,159415.84,"1846, 4205, 1848, 6196"]
["Reactome","R-HSA-975577","N-Glycan antennae elongation",0.4642461805033296,0.9726910685202514,15.0,3.0,202395.13333333333,"6480, 11320, 338596"]
["KEGG Pathways","hsa03320","PPAR signaling pathway",0.46503347323679994,0.8362444036275789,70.0,7.0,75551.52857142857,"1374, 2180, 4312, 4973, 8310, 9370, 23305"]
["Reactome","R-HSA-1433557","Signaling by SCF-KIT",0.46957813715217417,0.9726910685202514,334.0,40.0,148349.2125748503,"2675, 1846, 10019, 55615, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2887, 2903, 2905, 5293, 5295, 5689, 6714, 7006, 8452, 8660, 9542, 9861, 9965, 10000, 10076, 11221, 22821, 23239, 27327, 29851, 57690, 153090"]
["Reactome","R-HSA-198933","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",0.4722977029084301,0.9726910685202514,124.0,10.0,56103.91129032258,"1277, 3689, 718, 919, 999, 1278, 3695, 9436, 10225, 10870"]
["Reactome","R-HSA-194315","Signaling by Rho GTPases",0.47303045570166163,0.9726910685202514,433.0,48.0,140442.35103926098,"8379, 27237, 1499, 10395, 10458, 10499, 23263, 57522, 94134, 699, 999, 1063, 1124, 1855, 2810, 4627, 4638, 4650, 4688, 4690, 5501, 6242, 6714, 7204, 7410, 7456, 8353, 8874, 8997, 9639, 9828, 10451, 10672, 11214, 23002, 26230, 26999, 50650, 54848, 55839, 57449, 57636, 64411, 81565, 90627, 116985, 201176, 378708"]
["Reactome","R-HSA-5365859","RA biosynthesis pathway",0.47434543771365617,0.9726910685202514,23.0,4.0,156515.4347826087,"10170, 216, 9249, 157506"]
["Reactome","R-HSA-159418","Recycling of bile acids and salts",0.4755705969066914,0.9726910685202514,16.0,3.0,147333.25,"10499, 6579, 8647"]
["Reactome","R-HSA-1592230","Mitochondrial biogenesis",0.4797149384948775,0.9726910685202514,54.0,7.0,152307.96296296295,"10499, 10891, 51422, 1387, 2101, 9572, 80205"]
["Reactome","R-HSA-1630316","Glycosaminoglycan metabolism",0.4825063364428403,0.9726910685202514,124.0,18.0,211176.4193548387,"8534, 2817, 411, 1462, 1634, 2331, 3038, 4060, 4958, 6382, 9394, 9435, 9957, 10090, 23563, 64131, 92126, 375790"]
["Reactome","R-HSA-375280","Amine ligand-binding receptors",0.4840411763313731,0.9726910685202514,40.0,8.0,289531.425,"3274, 152, 146, 154, 155, 1128, 1131, 3351"]
["Reactome","R-HSA-442660","Na+/Cl- dependent neurotransmitter transporters",0.4869335896886906,0.9726910685202514,19.0,3.0,153693.84210526315,"6529, 6539, 6582"]
["Reactome","R-HSA-187037","NGF signalling via TRKA from the plasma membrane",0.48714336428839694,0.9726910685202514,384.0,47.0,154171.97916666666,"2675, 1846, 3708, 4205, 55615, 80824, 107, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2889, 2903, 2905, 3709, 5293, 5295, 5567, 5575, 5580, 5689, 5900, 6196, 6714, 8452, 8660, 9542, 9861, 9965, 10000, 11221, 22821, 23239, 27327, 29851, 57690, 153090, 196883"]
["Reactome","R-HSA-1433559","Regulation of KIT signaling",0.4884817392586967,0.9726910685202514,15.0,3.0,212140.06666666668,"10019, 2534, 6714"]
["Reactome","R-HSA-5423646","Aflatoxin activation and detoxification",0.48956647189740504,0.9726910685202514,19.0,2.0,59041.78947368421,"2678, 4258"]
["KEGG Pathways","hsa05410","Hypertrophic cardiomyopathy (HCM)",0.49170621797004227,0.8523718797756104,83.0,11.0,195575.53012048194,"6262, 3655, 783, 6546, 9254, 51422, 775, 3695, 4625, 55799, 93589"]
["Reactome","R-HSA-418346","Platelet homeostasis",0.49295757072747215,0.9726910685202514,88.0,13.0,209135.81818181818,"5152, 338, 3708, 6546, 491, 2778, 2793, 3709, 4842, 5051, 10242, 10335, 10846"]
["Reactome","R-HSA-422475","Axon guidance",0.49867699242476565,0.9726910685202514,564.0,75.0,206948.81028368796,"84448, 2675, 286, 1291, 6477, 783, 1289, 1846, 2049, 2817, 5362, 6092, 8912, 8913, 10154, 57522, 80031, 80824, 287, 775, 1212, 1282, 1293, 1808, 1847, 1848, 1946, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2887, 2903, 2905, 4627, 4690, 5293, 5295, 5567, 5689, 5909, 6196, 6585, 6714, 7204, 7410, 8440, 8452, 8660, 8828, 8829, 8874, 8997, 9353, 9423, 9542, 9861, 9965, 10371, 10451, 10486, 11221, 22821, 56963, 57698, 64218, 91584, 153090, 375790"]
["Reactome","R-HSA-432040","Vasopressin regulates renal water homeostasis via Aquaporins",0.5004885536189564,0.9726910685202514,43.0,6.0,128728.41860465116,"107, 2778, 2793, 5567, 5575, 196883"]
["Reactome","R-HSA-373755","Semaphorin interactions",0.5004945292541516,0.9726910685202514,67.0,10.0,212509.58208955225,"5362, 10154, 80031, 1808, 2534, 4627, 8829, 10371, 64218, 91584"]
["Reactome","R-HSA-418038","Nucleotide-like (purinergic) receptors",0.5014474955951894,0.9726910685202514,16.0,2.0,80856.6875,"140, 10161"]
["Reactome","R-HSA-2672351","Stimuli-sensing channels",0.502246087571265,0.9726910685202514,107.0,14.0,148457.20560747664,"6262, 55107, 57101, 41, 7439, 8737, 11035, 28962, 53373, 54795, 55515, 57719, 65125, 219931"]
["Reactome","R-HSA-74752","Signaling by Insulin receptor",0.5025827242558254,0.9726910685202514,320.0,37.0,142125.4125,"2675, 1846, 51422, 57521, 80824, 525, 528, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2887, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 10312, 11221, 22821, 55437, 64121, 90423, 153090"]
["Reactome","R-HSA-936837","Ion transport by P-type ATPases",0.5046777212305029,0.9726910685202514,56.0,8.0,136650.9107142857,"23250, 478, 486, 491, 10079, 23120, 79895, 344905"]
["KEGG Pathways","hsa04610","Complement and coagulation cascades",0.5078622237646009,0.8675979655978598,68.0,7.0,122383.83823529411,"623, 718, 1675, 2152, 2155, 5328, 5648"]
["Reactome","R-HSA-8864260","Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors",0.5103016140964491,0.9726910685202514,39.0,6.0,175306.2564102564,"5308, 348, 1081, 1387, 1956, 2099"]
["KEGG Pathways","hsa00052","Galactose metabolism",0.5137471368278801,0.8703980417331852,27.0,3.0,78333.07407407407,"8972, 5214, 57818"]
["Reactome","R-HSA-1250196","SHC1 events in ERBB2 signaling",0.5196401917074673,0.9726910685202514,22.0,4.0,288299.1818181818,"1956, 2066, 5580, 9542"]
["Reactome","R-HSA-8849932","SALM protein interactions at the synapses",0.5201993589894301,0.9726910685202514,21.0,4.0,415532.28571428574,"2890, 2903, 2905, 57497"]
["Reactome","R-HSA-1296072","Voltage gated Potassium channels",0.5204611642518151,0.9726910685202514,44.0,8.0,265565.70454545453,"3739, 3737, 3741, 3784, 3788, 7881, 9132, 90134"]
["Reactome","R-HSA-190828","Gap junction trafficking",0.5204892744274813,0.9726910685202514,46.0,5.0,90821.08695652174,"1212, 2697, 2700, 2702, 2703"]
["Reactome","R-HSA-535734","Fatty acid, triacylglycerol, and ketone body metabolism",0.5224776051075799,0.9726910685202514,247.0,28.0,130822.06477732793,"9612, 6095, 9663, 10499, 10891, 11332, 51422, 196, 622, 1374, 1387, 2101, 2180, 2274, 4862, 5244, 7003, 9572, 9915, 23179, 23205, 23305, 25937, 26027, 26230, 29841, 55326, 80205"]
["Reactome","R-HSA-381340","Transcriptional regulation of white adipocyte differentiation",0.5250888113353523,0.9726910685202514,86.0,11.0,158727.2093023256,"9612, 7026, 10499, 10891, 1052, 1387, 3952, 7480, 9314, 9370, 80205"]
["Reactome","R-HSA-1266695","Interleukin-7 signaling",0.5276982491927473,0.9726910685202514,27.0,3.0,177102.66666666666,"5295, 6597, 8353"]
["KEGG Pathways","hsa04744","Phototransduction",0.5294115262392289,0.8895849416314913,28.0,3.0,75493.21428571429,"810, 2779, 5957"]
["Reactome","R-HSA-114508","Effects of PIP2 hydrolysis",0.5310336854505835,0.9726910685202514,27.0,5.0,205687.96296296295,"3708, 747, 3709, 5580, 11343"]
["Reactome","R-HSA-2644602","Signaling by NOTCH1 PEST Domain Mutants in Cancer",0.5351281651435457,0.9726910685202514,58.0,8.0,157321.0344827586,"9612, 9759, 28514, 23462, 1387, 3714, 23493, 388585"]
["Reactome","R-HSA-2644603","Signaling by NOTCH1 in Cancer",0.5351281651435457,0.9726910685202514,58.0,8.0,157321.0344827586,"9612, 9759, 28514, 23462, 1387, 3714, 23493, 388585"]
["Reactome","R-HSA-2644606","Constitutive Signaling by NOTCH1 PEST Domain Mutants",0.5351281651435457,0.9726910685202514,58.0,8.0,157321.0344827586,"9612, 9759, 28514, 23462, 1387, 3714, 23493, 388585"]
["Reactome","R-HSA-2894858","Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer",0.5351281651435457,0.9726910685202514,58.0,8.0,157321.0344827586,"9612, 9759, 28514, 23462, 1387, 3714, 23493, 388585"]
["Reactome","R-HSA-2894862","Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants",0.5351281651435457,0.9726910685202514,58.0,8.0,157321.0344827586,"9612, 9759, 28514, 23462, 1387, 3714, 23493, 388585"]
["Reactome","R-HSA-6785631","ERBB2 Regulates Cell Motility",0.5362792086775545,0.9726910685202514,15.0,3.0,358506.4666666667,"1956, 2066, 9542"]
["Reactome","R-HSA-3928665","EPH-ephrin mediated repulsion of cells",0.5386201161044702,0.9726910685202514,49.0,7.0,293750.8367346939,"2049, 1212, 1946, 2534, 6714, 7410, 10451"]
["Reactome","R-HSA-1296071","Potassium Channels",0.5398473617798787,0.9726910685202514,100.0,15.0,244140.19,"3739, 2793, 3737, 3741, 3768, 3773, 3777, 3782, 3784, 3788, 7881, 9132, 10242, 54207, 90134"]
["Reactome","R-HSA-2173795","Downregulation of SMAD2/3:SMAD4 transcriptional activity",0.5463357442298223,0.9726910685202514,23.0,4.0,164188.21739130435,"4088, 9612, 4089, 6497"]
["KEGG Pathways","hsa00565","Ether lipid metabolism",0.5478638870730912,0.8984967747998696,35.0,4.0,143982.0285714286,"5051, 5168, 7941, 50487"]
["Reactome","R-HSA-6804114","TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest",0.5518144868086939,0.9726910685202514,19.0,2.0,63995.84210526316,"2810, 7027"]
["Reactome","R-HSA-5099900","WNT5A-dependent internalization of FZD4",0.5519649084287641,0.9726910685202514,15.0,2.0,94912.0,"1212, 7474"]
["Reactome","R-HSA-5576886","Phase 4 - resting membrane potential",0.5543770391760969,0.9726910685202514,19.0,3.0,189267.47368421053,"3768, 3777, 54207"]
["Reactome","R-HSA-2151201","Transcriptional activation of mitochondrial biogenesis",0.5555560451374638,0.9726910685202514,45.0,6.0,168297.3111111111,"10499, 10891, 1387, 2101, 9572, 80205"]
["Reactome","R-HSA-5358351","Signaling by Hedgehog",0.5585530254277015,0.9726910685202514,149.0,16.0,128041.61744966442,"2736, 5727, 107, 2737, 2778, 5034, 5567, 5575, 5689, 8452, 9861, 22873, 27152, 50846, 55733, 196883"]
["Reactome","R-HSA-5675221","Negative regulation of MAPK pathway",0.5594923756066978,0.9726910685202514,40.0,5.0,107867.1,"1846, 80824, 1847, 1848, 11221"]
["KEGG Pathways","hsa00190","Oxidative phosphorylation",0.5608747453729697,0.9053489984366834,116.0,9.0,63725.80172413793,"64077, 517, 525, 528, 1327, 6390, 10312, 56901, 90423"]
["Reactome","R-HSA-5218921","VEGFR2 mediated cell proliferation",0.5672025000456271,0.9726910685202514,256.0,31.0,155218.3515625,"2675, 1846, 3708, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 3709, 5580, 5689, 6714, 8452, 8660, 8877, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-1963640","GRB2 events in ERBB2 signaling",0.5704984637588457,0.9726910685202514,16.0,3.0,338906.25,"1956, 2066, 9542"]
["Reactome","R-HSA-2871796","FCERI mediated MAPK activation",0.5723184250008264,0.9726910685202514,266.0,32.0,154302.95864661655,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 3937, 4214, 5689, 6416, 6714, 7410, 8452, 8660, 9542, 9861, 9965, 10451, 11221, 22821, 153090"]
["Reactome","R-HSA-5675482","Regulation of necroptotic cell death",0.5736054637890762,0.9726910685202514,18.0,2.0,70134.11111111111,"8743, 8737"]
["Reactome","R-HSA-1912422","Pre-NOTCH Expression and Processing",0.5743706837930016,0.9726910685202514,46.0,6.0,147886.73913043478,"595, 1387, 3955, 7027, 27327, 57690"]
["Reactome","R-HSA-4086400","PCP/CE pathway",0.5768575762466652,0.9726910685202514,92.0,9.0,95913.28260869565,"8321, 1212, 1855, 4920, 5689, 7474, 7481, 9861, 23002"]
["Reactome","R-HSA-549132","Organic cation/anion/zwitterion transport",0.579682081733284,0.9726910685202514,15.0,2.0,113669.33333333333,"6582, 55867"]
["Reactome","R-HSA-2559585","Oncogene Induced Senescence",0.5822907486972138,0.9726910685202514,32.0,4.0,115949.53125,"2114, 7027, 27327, 57690"]
["KEGG Pathways","hsa01040","Biosynthesis of unsaturated fatty acids",0.5896045388550506,0.9226635913380563,21.0,2.0,58917.142857142855,"11332, 8310"]
["Reactome","R-HSA-189200","Hexose transport",0.5957521299941022,0.9726910685202514,53.0,5.0,75772.62264150943,"6513, 6518, 8021, 23225, 57818"]
["Reactome","R-HSA-156584","Cytosolic sulfonation of small molecules",0.5964769431934257,0.9726910685202514,19.0,2.0,70139.21052631579,"6817, 6819"]
["Reactome","R-HSA-1168372","Downstream signaling events of B Cell Receptor (BCR)",0.601404986778848,0.9726910685202514,196.0,23.0,143958.443877551,"55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 5293, 5295, 5689, 6714, 8660, 9542, 9861, 9965, 10000, 23239, 27327, 29851, 57690"]
["KEGG Pathways","hsa04964","Proximal tubule bicarbonate reclamation",0.6027023835953136,0.9360150654321158,23.0,3.0,147494.86956521738,"478, 486, 762"]
["Reactome","R-HSA-438064","Post NMDA receptor activation events",0.6083626064515197,0.9726910685202514,36.0,6.0,195118.11111111112,"107, 2903, 2905, 5567, 6196, 84254"]
["Reactome","R-HSA-111996","Ca-dependent events",0.6085806119169508,0.9726910685202514,29.0,5.0,246104.89655172414,"107, 5567, 5575, 5580, 196883"]
["Reactome","R-HSA-8853659","RET signaling",0.6127379046392712,0.9726910685202514,267.0,32.0,158236.28464419476,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2887, 2903, 2905, 5293, 5295, 5567, 5689, 5909, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-5674400","Constitutive Signaling by AKT1 E17K in Cancer",0.617859526185855,0.9726910685202514,25.0,3.0,101099.92,"55615, 2308, 10000"]
["Reactome","R-HSA-166016","Toll Like Receptor 4 (TLR4) Cascade",0.618291390073022,0.9726910685202514,128.0,15.0,136019.5,"1846, 3689, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 7187, 8737, 10333, 11035, 64127, 653509"]
["Reactome","R-HSA-112310","Neurotransmitter Release Cycle",0.6193752918750396,0.9726910685202514,50.0,7.0,169070.66,"10815, 2572, 6529, 6539, 6582, 8499, 60482"]
["Reactome","R-HSA-181430","Norepinephrine Neurotransmitter Release Cycle",0.6197205265115094,0.9726910685202514,18.0,3.0,227701.44444444444,"10815, 6582, 8499"]
["Reactome","R-HSA-445355","Smooth Muscle Contraction",0.6271568783435679,0.9726910685202514,34.0,4.0,112482.0294117647,"5829, 8291, 4638, 93408"]
["Reactome","R-HSA-392851","Prostacyclin signalling through prostacyclin receptor",0.6276569717614426,0.9726910685202514,19.0,2.0,71283.78947368421,"2778, 2793"]
["KEGG Pathways","hsa00010","Glycolysis / Gluconeogenesis",0.6322076192892956,0.9492096985048285,65.0,6.0,88035.63076923077,"125, 229, 5214, 57818, 84532, 130589"]
["KEGG Pathways","hsa04370","VEGF signaling pathway",0.6329444964444934,0.9492096985048285,75.0,8.0,126488.45333333334,"5829, 4772, 5293, 5295, 6714, 8877, 10000, 50487"]
["Reactome","R-HSA-389513","CTLA4 inhibitory signaling",0.633913863603143,0.9726910685202514,22.0,3.0,111739.72727272728,"2534, 6714, 10000"]
["Reactome","R-HSA-202427","Phosphorylation of CD3 and TCR zeta chains",0.6346300082822656,0.9726910685202514,20.0,2.0,65165.05,"919, 55824"]
["KEGG Pathways","hsa00592","alpha-Linolenic acid metabolism",0.6419824057687784,0.9492096985048285,19.0,2.0,155358.73684210525,"8310, 50487"]
["Reactome","R-HSA-8849471","PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases",0.6485845125194001,0.9726910685202514,27.0,4.0,168589.44444444444,"5829, 9844, 22821, 153090"]
["Reactome","R-HSA-166054","Activated TLR4 signalling",0.648822294453063,0.9726910685202514,114.0,13.0,132570.16666666666,"1846, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 7187, 8737, 10333, 11035, 64127"]
["Reactome","R-HSA-4419969","Depolymerisation of the Nuclear Lamina",0.6501183194070477,0.9726910685202514,15.0,2.0,103237.73333333334,"9663, 221496"]
["Reactome","R-HSA-2691230","Signaling by NOTCH1 HD Domain Mutants in Cancer",0.6537575177709708,0.9726910685202514,15.0,2.0,126349.66666666667,"28514, 3714"]
["Reactome","R-HSA-2691232","Constitutive Signaling by NOTCH1 HD Domain Mutants",0.6537575177709708,0.9726910685202514,15.0,2.0,126349.66666666667,"28514, 3714"]
["Reactome","R-HSA-111447","Activation of BAD and translocation to mitochondria ",0.6584385324043449,0.9726910685202514,15.0,2.0,108982.8,"2810, 10000"]
["Reactome","R-HSA-983705","Signaling by the B Cell Receptor (BCR)",0.6643621028327598,0.9726910685202514,226.0,26.0,144254.14159292035,"3708, 55615, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 3709, 4690, 5293, 5295, 5689, 6714, 8660, 9542, 9861, 9965, 10000, 23239, 27327, 29851, 57690"]
["Reactome","R-HSA-210745","Regulation of gene expression in beta cells",0.6665013714779903,0.9726910685202514,20.0,3.0,170773.75,"2308, 5080, 10000"]
["Reactome","R-HSA-442755","Activation of NMDA receptor upon glutamate binding and postsynaptic events",0.676891386757074,0.9726910685202514,40.0,7.0,258633.85,"2890, 107, 2903, 2905, 5567, 6196, 84254"]
["Reactome","R-HSA-5683057","MAPK family signaling cascades",0.679268000502276,0.9726910685202514,288.0,34.0,156606.05555555556,"2675, 1846, 10435, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 2668, 2674, 2903, 2905, 5567, 5689, 6714, 8452, 8660, 8997, 9542, 9861, 9965, 10602, 11221, 22821, 27327, 57690, 153090"]
["KEGG Pathways","hsa05150","Staphylococcus aureus infection",0.6827732734830643,0.9653001452691597,52.0,4.0,68680.88461538461,"3689, 718, 1675, 5648"]
["Reactome","R-HSA-909733","Interferon alpha/beta signaling",0.6863703322420744,0.9726910685202514,67.0,5.0,53245.40298507463,"3394, 3660, 4600, 9021, 10410"]
["Reactome","R-HSA-877300","Interferon gamma signaling",0.6881076657066536,0.9726910685202514,91.0,9.0,108617.16483516483,"3394, 3458, 3660, 5580, 9021, 10346, 23650, 81603, 115361"]
["Reactome","R-HSA-5663213","RHO GTPases Activate WASPs and WAVEs",0.6886126957794334,0.9726910685202514,36.0,4.0,91333.66666666667,"10458, 4690, 7456, 26999"]
["Reactome","R-HSA-2586552","Signaling by Leptin",0.6887810162658996,0.9726910685202514,251.0,29.0,151656.390438247,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 3952, 5689, 6714, 8452, 8660, 9021, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-165159","mTOR signalling",0.6911524281978962,0.9726910685202514,39.0,4.0,88661.58974358975,"51422, 57521, 55437, 64121"]
["Reactome","R-HSA-977225","Amyloid fiber formation",0.6916379597056266,0.9726910685202514,95.0,6.0,61505.642105263156,"6477, 325, 337, 5071, 6653, 8353"]
["KEGG Pathways","hsa04977","Vitamin digestion and absorption",0.693536100208276,0.9738006886486068,24.0,3.0,159463.875,"338, 337, 113278"]
["Reactome","R-HSA-112316","Neuronal System",0.6937379941078845,0.9726910685202514,344.0,49.0,257547.56104651163,"9369, 3739, 9379, 783, 2890, 9254, 10815, 347731, 107, 590, 773, 1740, 2037, 2562, 2572, 2793, 2898, 2900, 2901, 2903, 2905, 3737, 3741, 3768, 3773, 3777, 3782, 3784, 3788, 5330, 5567, 6196, 6529, 6539, 6582, 7881, 8499, 9132, 9228, 10242, 26045, 54207, 55799, 57497, 60482, 84254, 90134, 91683, 196883"]
["Reactome","R-HSA-420092","Glucagon-type ligand receptors",0.6965090457938428,0.9726910685202514,30.0,3.0,77450.33333333333,"2691, 2778, 2793"]
["Reactome","R-HSA-373753","Nephrin interactions",0.6983306620718543,0.9726910685202514,23.0,4.0,267834.7826086957,"2534, 4690, 5295, 8440"]
["Reactome","R-HSA-2980736","Peptide hormone metabolism",0.700057391487343,0.9726910685202514,90.0,11.0,163534.8111111111,"6934, 1499, 590, 1081, 3952, 5080, 5972, 7941, 9314, 54536, 83729"]
["Reactome","R-HSA-2173789","TGF-beta receptor signaling activates SMADs",0.7010354588116549,0.9726910685202514,32.0,4.0,134920.40625,"4088, 4089, 5501, 56937"]
["Reactome","R-HSA-1251985","Nuclear signaling by ERBB4",0.701675323271792,0.9726910685202514,25.0,4.0,291679.64,"6387, 2066, 2099, 9542"]
["Reactome","R-HSA-5621575","CD209 (DC-SIGN) signaling",0.704785788856237,0.9726910685202514,22.0,3.0,121182.09090909091,"1387, 2534, 5567"]
["Reactome","R-HSA-70153","Glucose transport",0.7075770904506598,0.9726910685202514,45.0,4.0,76007.28888888888,"6513, 8021, 23225, 57818"]
["Reactome","R-HSA-445717","Aquaporin-mediated transport",0.7081910941992886,0.9726910685202514,52.0,6.0,115106.80769230769,"107, 2778, 2793, 5567, 5575, 196883"]
["KEGG Pathways","hsa04940","Type I diabetes mellitus",0.7085195521171792,0.9844861168531089,41.0,4.0,83112.90243902439,"2572, 3458, 3553, 3592"]
["Reactome","R-HSA-15869","Metabolism of nucleotides",0.7118950097884937,0.9726910685202514,96.0,9.0,85803.08333333333,"954, 64077, 272, 955, 1807, 2745, 4521, 9583, 100500832"]
["KEGG Pathways","hsa05140","Leishmaniasis",0.7211901816088652,0.9922415250323312,70.0,7.0,107954.5,"3689, 718, 3458, 3553, 3592, 4688, 7099"]
["Reactome","R-HSA-1445148","Translocation of GLUT4 to the plasma membrane",0.7229662834304962,0.9726910685202514,80.0,8.0,97415.6,"51422, 2810, 4625, 5867, 22989, 23216, 54536, 57186"]
["Reactome","R-HSA-8854214","TBC/RABGAPs",0.7281470199127664,0.9726910685202514,45.0,4.0,71068.53333333334,"125058, 5867, 51762, 57533"]
["Reactome","R-HSA-512988","Interleukin-3, 5 and GM-CSF signaling",0.7301950525059068,0.9726910685202514,269.0,31.0,153145.69144981413,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2889, 2903, 2905, 5293, 5295, 5689, 6714, 7006, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-418360","Platelet calcium homeostasis",0.7323074758931333,0.9726910685202514,29.0,4.0,174883.06896551725,"3708, 6546, 491, 3709"]
["Reactome","R-HSA-5654720","PI-3K cascade:FGFR4",0.7326630924478845,0.9726910685202514,20.0,3.0,180008.75,"2264, 5295, 9965"]
["Reactome","R-HSA-2173791","TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)",0.7376588067629867,0.9726910685202514,16.0,2.0,166002.5,"56288, 50848"]
["Reactome","R-HSA-3371556","Cellular response to heat stress",0.745174847829922,0.9726910685202514,89.0,8.0,83612.73033707865,"3281, 57521, 1387, 3313, 8021, 23225, 26353, 116835"]
["Reactome","R-HSA-109703","PKB-mediated events",0.7464597106482659,0.9726910685202514,40.0,4.0,89491.275,"51422, 57521, 55437, 64121"]
["KEGG Pathways","hsa04621","NOD-like receptor signaling pathway",0.748036278014899,0.9989248813013669,58.0,6.0,114313.29310344828,"834, 3553, 9051, 55914, 64127, 260434"]
["Reactome","R-HSA-1236394","Signaling by ERBB4",0.7551412890365978,0.9726910685202514,43.0,6.0,235212.60465116278,"6387, 1956, 2066, 2099, 5295, 9542"]
["Reactome","R-HSA-201451","Signaling by BMP",0.7556439604782071,0.9726910685202514,24.0,4.0,215400.58333333334,"650, 4086, 4089, 6497"]
["KEGG Pathways","hsa04150","mTOR signaling pathway",0.7556940577650288,0.9989248813013669,52.0,6.0,140088.32692307694,"7424, 57521, 5293, 5295, 6196, 10000"]
["Reactome","R-HSA-5687128","MAPK6/MAPK4 signaling",0.7584900082480759,0.9726910685202514,89.0,9.0,115028.37078651685,"10435, 2308, 5567, 5689, 8997, 9861, 10602, 27327, 57690"]
["Reactome","R-HSA-917937","Iron uptake and transport",0.7604658270620596,0.9726910685202514,44.0,4.0,75046.47727272728,"525, 528, 10312, 90423"]
["KEGG Pathways","hsa00670","One carbon pool by folate",0.7608658850590452,0.9989248813013669,18.0,2.0,92882.5,"6472, 25902"]
["Reactome","R-HSA-450282","MAPK targets/ Nuclear events mediated by MAP kinases",0.7695566540848746,0.9726910685202514,31.0,4.0,157652.25806451612,"1846, 4205, 1848, 6196"]
["KEGG Pathways","hsa04080","Neuroactive ligand-receptor interaction",0.7714131058401197,0.9989248813013669,269.0,35.0,221734.72118959107,"3274, 152, 623, 2890, 2914, 56288, 140, 146, 154, 155, 185, 1081, 1128, 1131, 1269, 2562, 2693, 2741, 2894, 2895, 2898, 2900, 2901, 2903, 2905, 3351, 3952, 6754, 7201, 7433, 10161, 10316, 23566, 53637, 56923"]
["Reactome","R-HSA-446219","Synthesis of substrates in N-glycan biosythesis",0.7722016703643726,0.9726910685202514,63.0,7.0,130151.84126984127,"6480, 9945, 29926, 2762, 8869, 256281, 338596"]
["Reactome","R-HSA-912526","Interleukin receptor SHC signaling",0.7742030176448913,0.9726910685202514,253.0,29.0,155703.89723320157,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5293, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-75876","Synthesis of very long-chain fatty acyl-CoAs",0.7770816533260908,0.9726910685202514,27.0,3.0,156857.40740740742,"2180, 23205, 23305"]
["Reactome","R-HSA-2028269","Signaling by Hippo",0.7810103351653961,0.9726910685202514,21.0,3.0,163167.7619047619,"9113, 9414, 25937"]
["Reactome","R-HSA-166166","MyD88-independent TLR3/TLR4 cascade ",0.7831977938622803,0.9726910685202514,99.0,11.0,136191.9090909091,"1846, 4205, 1848, 6196, 6416, 7098, 7099, 7187, 8737, 11035, 64127"]
["Reactome","R-HSA-168164","Toll Like Receptor 3 (TLR3) Cascade",0.7831977938622803,0.9726910685202514,99.0,11.0,136191.9090909091,"1846, 4205, 1848, 6196, 6416, 7098, 7099, 7187, 8737, 11035, 64127"]
["Reactome","R-HSA-937061","TRIF-mediated TLR3/TLR4 signaling ",0.7831977938622803,0.9726910685202514,99.0,11.0,136191.9090909091,"1846, 4205, 1848, 6196, 6416, 7098, 7099, 7187, 8737, 11035, 64127"]
["KEGG Pathways","hsa03022","Basal transcription factors",0.7848748515008099,0.9989248813013669,35.0,3.0,67517.4,"6874, 9569, 11037"]
["Reactome","R-HSA-74751","Insulin receptor signalling cascade",0.7850346738570779,0.9726910685202514,295.0,33.0,148117.27796610168,"2675, 1846, 51422, 57521, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2887, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 55437, 64121, 153090"]
["Reactome","R-HSA-75153","Apoptotic execution  phase",0.7851518047120077,0.9726910685202514,52.0,6.0,150705.53846153847,"1499, 324, 999, 3005, 5580, 9414"]
["Reactome","R-HSA-418217","G beta:gamma signalling through PLC beta",0.7892437956913947,0.9726910685202514,20.0,2.0,105260.6,"2793, 5330"]
["KEGG Pathways","hsa00533","Glycosaminoglycan biosynthesis - keratan sulfate",0.7895660824239333,0.9989248813013669,15.0,2.0,169568.53333333333,"8534, 9435"]
["Reactome","R-HSA-5632684","Hedgehog 'on' state",0.796312233002228,0.9726910685202514,85.0,8.0,97851.5411764706,"2736, 5727, 2737, 5689, 8452, 9861, 22873, 50846"]
["Reactome","R-HSA-5610787","Hedgehog 'off' state",0.8061800127175393,0.9726910685202514,113.0,11.0,109198.30973451327,"2736, 5727, 107, 2737, 2778, 5567, 5575, 5689, 9861, 27152, 196883"]
["Reactome","R-HSA-6794361","Interactions of neurexins and neuroligins at synapses",0.8063301306930291,0.9726910685202514,57.0,10.0,429363.2807017544,"9369, 9379, 347731, 1740, 2037, 2903, 2905, 9228, 26045, 91683"]
["Reactome","R-HSA-380994","ATF4 activates genes",0.8132399963614585,0.9726910685202514,26.0,2.0,58243.88461538462,"467, 3484"]
["Reactome","R-HSA-3214847","HATs acetylate histones",0.8139486110856329,0.9726910685202514,138.0,9.0,59532.8768115942,"10499, 1387, 5077, 8353, 11091, 11143, 23522, 55250, 117143"]
["Reactome","R-HSA-1226099","Signaling by FGFR in disease",0.8159247292904438,0.9726910685202514,63.0,7.0,131391.60317460317,"2252, 2260, 2261, 2263, 2264, 5295, 11064"]
["Reactome","R-HSA-5635838","Activation of SMO",0.8223009679049161,0.9726910685202514,18.0,2.0,106701.61111111111,"5727, 50846"]
["KEGG Pathways","hsa04710","Circadian rhythm",0.8256698187765512,0.9989248813013669,22.0,3.0,197643.0909090909,"6095, 4862, 9572"]
["Reactome","R-HSA-6806003","Regulation of TP53 Expression and Degradation",0.8274726348834521,0.9726910685202514,36.0,4.0,118509.33333333333,"639, 55615, 10000, 11200"]
["Reactome","R-HSA-196071","Metabolism of steroid hormones",0.8313212628865498,0.9726910685202514,32.0,3.0,79868.0625,"1081, 3290, 6716"]
["KEGG Pathways","hsa05016","Huntington's disease",0.8319889579021306,0.9989248813013669,174.0,14.0,90800.08620689655,"3708, 10891, 317, 517, 627, 1212, 1327, 1387, 1639, 5330, 6390, 6874, 56901, 90993"]
["Reactome","R-HSA-196757","Metabolism of folate and pterines",0.8334861385494332,0.9726910685202514,17.0,2.0,113311.58823529411,"6472, 25902"]
["Reactome","R-HSA-111465","Apoptotic cleavage of cellular proteins",0.8369703555123982,0.9726910685202514,38.0,5.0,188179.97368421053,"1499, 324, 999, 5580, 9414"]
["Reactome","R-HSA-1660499","Synthesis of PIPs at the plasma membrane",0.8376060912039279,0.9726910685202514,49.0,6.0,151780.14285714287,"5287, 5293, 5295, 5867, 22874, 54477"]
["Reactome","R-HSA-2299718","Condensation of Prophase Chromosomes",0.8386014670530749,0.9726910685202514,69.0,3.0,45428.014492753624,"5925, 8353, 79648"]
["Reactome","R-HSA-5637810","Constitutive Signaling by EGFRvIII",0.8433251619625364,0.9726910685202514,16.0,2.0,163207.0,"1956, 5295"]
["Reactome","R-HSA-5637812","Signaling by EGFRvIII in Cancer",0.8433251619625364,0.9726910685202514,16.0,2.0,163207.0,"1956, 5295"]
["Reactome","R-HSA-139853","Elevation of cytosolic Ca2+ levels",0.8449224896311783,0.9726910685202514,16.0,2.0,150669.625,"3708, 3709"]
["Reactome","R-HSA-913531","Interferon Signaling",0.850449470317135,0.9726910685202514,194.0,16.0,87270.73195876289,"3394, 317649, 2317, 3458, 3660, 4600, 5580, 7318, 8021, 9021, 10346, 10410, 23225, 23650, 81603, 115361"]
["Reactome","R-HSA-1296041","Activation of G protein gated Potassium channels",0.8532094136394089,0.9726910685202514,25.0,3.0,172987.2,"2793, 3768, 3773"]
["Reactome","R-HSA-1296059","G protein gated Potassium channels",0.8532094136394089,0.9726910685202514,25.0,3.0,172987.2,"2793, 3768, 3773"]
["Reactome","R-HSA-997272","Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits",0.8532094136394089,0.9726910685202514,25.0,3.0,172987.2,"2793, 3768, 3773"]
["Reactome","R-HSA-170968","Frs2-mediated activation",0.8533110306370718,0.9726910685202514,248.0,28.0,154353.35483870967,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2889, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-983231","Factors involved in megakaryocyte development and platelet production",0.8535491413252648,0.9726910685202514,170.0,16.0,117437.25882352941,"10019, 23348, 547, 832, 1387, 3660, 4602, 5567, 5575, 5890, 8353, 9732, 26153, 91768, 140628, 221458"]
["Reactome","R-HSA-6794362","Protein-protein interactions at synapses",0.8538421233873508,0.9726910685202514,71.0,12.0,446937.5211267606,"9369, 9379, 2890, 347731, 1740, 2037, 2903, 2905, 9228, 26045, 57497, 91683"]
["Reactome","R-HSA-452723","Transcriptional regulation of pluripotent stem cells",0.8560840177194855,0.9726910685202514,36.0,4.0,191494.97222222222,"27086, 4089, 5087, 9314"]
["Reactome","R-HSA-5621481","C-type lectin receptors (CLRs)",0.8569517056251053,0.9726910685202514,138.0,13.0,96240.13043478261,"3708, 1387, 2534, 3553, 3709, 4585, 4772, 5567, 5580, 5689, 6714, 9020, 9861"]
["Reactome","R-HSA-1483255","PI Metabolism",0.8632114316488926,0.9726910685202514,78.0,9.0,138988.28205128206,"5287, 5293, 5295, 5867, 9108, 22874, 25816, 54477, 388121"]
["KEGG Pathways","hsa04110","Cell cycle",0.8677608972802355,0.9989248813013669,123.0,12.0,105025.28455284552,"4088, 8379, 595, 699, 894, 1387, 2810, 4089, 4616, 5925, 7027, 11200"]
["Reactome","R-HSA-5654228","Phospholipase C-mediated cascade; FGFR4",0.869782609289903,0.9726910685202514,15.0,2.0,145691.0,"2264, 9965"]
["Reactome","R-HSA-166208","mTORC1-mediated signalling",0.8743517091769671,0.9726910685202514,22.0,2.0,89904.54545454546,"57521, 64121"]
["Reactome","R-HSA-1280218","Adaptive Immune System",0.8754351939054286,0.9726910685202514,819.0,78.0,114423.85958485959,"1277, 80176, 6477, 3689, 3708, 11069, 29116, 55615, 718, 919, 999, 1278, 1513, 1514, 1639, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2533, 2534, 3695, 3702, 3709, 3937, 4688, 4690, 5071, 5293, 5295, 5493, 5567, 5689, 5909, 6714, 7099, 7318, 7336, 7704, 8452, 8660, 8764, 8924, 8925, 9020, 9021, 9436, 9542, 9861, 9902, 9965, 10000, 10225, 10333, 10422, 10870, 22954, 23239, 25897, 25898, 26153, 26259, 27327, 29851, 55521, 55819, 55824, 57690, 84541, 84676, 84708, 92369, 144699, 153579"]
["KEGG Pathways","hsa00350","Tyrosine metabolism",0.8767653060985331,0.9989248813013669,41.0,4.0,127949.0,"125, 1621, 7173, 7306"]
["Reactome","R-HSA-112399","IRS-mediated signalling",0.8773030109717074,0.9726910685202514,292.0,32.0,148002.59931506848,"2675, 1846, 51422, 57521, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 55437, 64121, 153090"]
["KEGG Pathways","hsa04614","Renin-angiotensin system",0.8788819157783843,0.9989248813013669,17.0,2.0,163073.17647058822,"185, 5972"]
["Reactome","R-HSA-5205647","Mitophagy",0.8806218666067515,0.9726910685202514,22.0,2.0,108965.27272727272,"5071, 9804"]
["Reactome","R-HSA-5205685","Pink/Parkin Mediated Mitophagy",0.8806218666067515,0.9726910685202514,22.0,2.0,108965.27272727272,"5071, 9804"]
["Reactome","R-HSA-187687","Signalling to ERKs",0.8821542823182771,0.9726910685202514,261.0,29.0,151769.6398467433,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2889, 2903, 2905, 5689, 5900, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-975163","IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation",0.8852201337830797,0.9726910685202514,16.0,2.0,178493.0625,"7098, 7099"]
["Reactome","R-HSA-375276","Peptide ligand-binding receptors",0.886402302042988,0.9726910685202514,187.0,20.0,130700.21390374332,"623, 50865, 6387, 185, 718, 1232, 1236, 1907, 2693, 2861, 3640, 3792, 6754, 7200, 7201, 10316, 10563, 10874, 56923, 347148"]
["Reactome","R-HSA-167044","Signalling to RAS",0.886492120890014,0.9726910685202514,254.0,28.0,150775.98031496062,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 5900, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-438066","Unblocking of NMDA receptor, glutamate binding and activation",0.8896981360360782,0.9726910685202514,17.0,3.0,333662.1176470588,"2890, 2903, 2905"]
["Reactome","R-HSA-418597","G alpha (z) signalling events",0.8908506175566913,0.9726910685202514,47.0,6.0,158235.8510638298,"152, 107, 2778, 2793, 5580, 196883"]
["Reactome","R-HSA-164952","The role of Nef in HIV-1 replication and disease pathogenesis",0.8914717396136496,0.9726910685202514,29.0,3.0,109781.86206896552,"919, 2534, 9844"]
["KEGG Pathways","hsa04950","Maturity onset diabetes of the young",0.8919279139902693,0.9989248813013669,24.0,3.0,184604.5,"2494, 5080, 6928"]
["Reactome","R-HSA-169893","Prolonged ERK activation events",0.8929824955484073,0.9726910685202514,250.0,28.0,154106.812,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2889, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-380108","Chemokine receptors bind chemokines",0.8936021018670449,0.9726910685202514,48.0,4.0,75719.02083333333,"6387, 1232, 1236, 10563"]
["Reactome","R-HSA-75105","Fatty Acyl-CoA Biosynthesis",0.8943559392975462,0.9726910685202514,53.0,5.0,119482.58490566038,"11332, 2180, 23205, 23305, 26027"]
["Reactome","R-HSA-1643685","Disease",0.8952259088601737,0.9726910685202514,840.0,84.0,130581.09166666666,"4088, 9612, 6934, 7058, 9759, 10417, 28514, 79139, 1499, 2817, 10015, 23462, 54437, 55615, 56999, 79875, 140766, 170691, 324, 831, 919, 999, 1387, 1462, 1634, 1956, 2060, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2331, 2534, 3714, 4060, 4089, 4585, 4958, 5293, 5295, 5689, 5947, 6156, 6228, 6229, 6382, 6416, 6714, 6874, 7057, 7098, 7099, 7100, 7187, 8021, 8660, 8812, 9509, 9525, 9542, 9844, 9861, 9965, 10000, 10018, 10333, 11064, 11096, 22821, 23225, 23493, 29851, 50846, 54507, 57188, 80731, 153090, 170692, 375790, 388585, 653509"]
["Reactome","R-HSA-451927","Interleukin-2 signaling",0.8968414449996067,0.9726910685202514,260.0,29.0,154655.20769230768,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5293, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-69231","Cyclin D associated events in G1",0.8992409852887208,0.9726910685202514,39.0,4.0,105440.35897435897,"595, 894, 5925, 7027"]
["Reactome","R-HSA-69236","G1 Phase",0.8992409852887208,0.9726910685202514,39.0,4.0,105440.35897435897,"595, 894, 5925, 7027"]
["Reactome","R-HSA-3299685","Detoxification of Reactive Oxygen Species",0.9041283132167468,0.9726910685202514,37.0,3.0,68994.56756756757,"2878, 4688, 5034"]
["Reactome","R-HSA-112412","SOS-mediated signalling",0.9065945032234392,0.9726910685202514,243.0,27.0,154209.58847736625,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-179812","GRB2 events in EGFR signaling",0.9065945032234392,0.9726910685202514,243.0,27.0,154209.58847736625,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-180336","SHC1 events in EGFR signaling",0.9065945032234392,0.9726910685202514,243.0,27.0,154209.58847736625,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-5673001","RAF/MAP kinase cascade",0.9065945032234392,0.9726910685202514,243.0,27.0,154209.58847736625,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-112315","Transmission across Chemical Synapses",0.9078936418484569,0.9726910685202514,213.0,28.0,200396.87323943662,"783, 2890, 9254, 10815, 107, 590, 773, 2562, 2572, 2793, 2898, 2900, 2901, 2903, 2905, 3768, 3773, 5330, 5567, 6196, 6529, 6539, 6582, 8499, 55799, 60482, 84254, 196883"]
["Reactome","R-HSA-2024096","HS-GAG degradation",0.9089344802249404,0.9726910685202514,22.0,3.0,235670.54545454544,"2817, 6382, 375790"]
["Reactome","R-HSA-397795","G-protein beta:gamma signalling",0.9090297023910504,0.9726910685202514,51.0,5.0,115937.64705882352,"2793, 5293, 5295, 5330, 10000"]
["KEGG Pathways","hsa04070","Phosphatidylinositol signaling system",0.9145789939781781,0.9989248813013669,77.0,9.0,165585.8051948052,"810, 3708, 5287, 3632, 3706, 3709, 5293, 5295, 5330"]
["Reactome","R-HSA-937072","TRAF6 mediated induction of TAK1 complex",0.916042696856174,0.9726910685202514,17.0,2.0,169556.4705882353,"7098, 7099"]
["Reactome","R-HSA-5607764","CLEC7A (Dectin-1) signaling",0.9161046927561876,0.9726910685202514,99.0,9.0,96351.23232323233,"3708, 3553, 3709, 4772, 5580, 5689, 6714, 9020, 9861"]
["KEGG Pathways","hsa05100","Bacterial invasion of epithelial cells",0.9171611456032073,0.9989248813013669,70.0,8.0,184612.12857142856,"5829, 1499, 999, 1212, 5293, 5295, 6714, 9844"]
["Reactome","R-HSA-5669034","TNFs bind their physiological receptors",0.9171628942400745,0.9726910685202514,28.0,3.0,119493.5,"7292, 8764, 10673"]
["Reactome","R-HSA-76002","Platelet activation, signaling and aggregation",0.9188059317155026,0.9726910685202514,274.0,29.0,149884.78467153283,"152, 1277, 3708, 7123, 7424, 11069, 1, 747, 1278, 1675, 2534, 2768, 2793, 3709, 3937, 5293, 5295, 5580, 6714, 7057, 7066, 7078, 7410, 10000, 10451, 10672, 11343, 51097, 54863"]
["Reactome","R-HSA-425366","Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds",0.9222162301941641,0.9726910685202514,104.0,11.0,163637.83653846153,"6513, 6518, 6529, 6539, 6582, 9123, 55867, 56606, 57181, 60482, 146802"]
["Reactome","R-HSA-5358346","Hedgehog ligand biogenesis",0.9241899243680927,0.9726910685202514,65.0,5.0,111594.4,"5034, 5689, 9861, 50846, 55733"]
["Reactome","R-HSA-425407","SLC-mediated transmembrane transport",0.9320441217316351,0.9726910685202514,282.0,29.0,135649.31560283687,"6546, 121260, 1811, 2030, 3177, 6509, 6510, 6513, 6518, 6522, 6529, 6539, 6579, 6582, 8021, 9056, 9123, 10723, 23225, 28232, 51296, 55867, 56606, 57181, 57419, 57818, 60482, 124935, 146802"]
["Reactome","R-HSA-4839743","phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-5339716","Misspliced GSK3beta mutants stabilize beta-catenin",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-5358747","S33 mutants of beta-catenin aren't phosphorylated",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-5358749","S37 mutants of beta-catenin aren't phosphorylated",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-5358751","S45 mutants of beta-catenin aren't phosphorylated",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-5358752","T41 mutants of beta-catenin aren't phosphorylated",0.9326050256417728,0.9726910685202514,15.0,2.0,148727.33333333334,"1499, 324"]
["Reactome","R-HSA-381042","PERK regulates gene expression",0.9339993793931739,0.9726910685202514,29.0,2.0,57052.41379310345,"467, 3484"]
["Reactome","R-HSA-382551","Transmembrane transport of small molecules",0.9419889944801108,0.9781845370153696,675.0,69.0,129721.65037037036,"6262, 79139, 6546, 23250, 55107, 57101, 121260, 41, 107, 478, 486, 491, 525, 528, 1811, 2030, 2039, 2562, 2741, 2778, 2793, 3177, 5244, 5567, 5575, 5689, 6509, 6510, 6513, 6518, 6522, 6529, 6539, 6579, 6582, 7439, 8021, 8737, 9056, 9123, 9861, 10079, 10312, 10723, 11035, 23120, 23225, 23460, 28232, 28962, 51296, 53373, 54795, 55515, 55867, 56606, 57181, 57419, 57719, 57818, 60482, 65125, 79895, 90423, 124935, 146802, 196883, 219931, 344905"]
["Reactome","R-HSA-162588","Budding and maturation of HIV virion",0.9436877315632991,0.9782471833295548,25.0,2.0,100531.84,"10015, 9525"]
["Reactome","R-HSA-500657","Presynaptic function of Kainate receptors",0.9449917717169392,0.9784828594118881,21.0,2.0,116396.95238095238,"2793, 5330"]
["Reactome","R-HSA-2122948","Activated NOTCH1 Transmits Signal to the Nucleus",0.9473728270423152,0.980009594289706,30.0,3.0,120439.63333333333,"28514, 3714, 23220"]
["Reactome","R-HSA-5693565","Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",0.9502818461361056,0.9804681205236514,74.0,5.0,67657.28378378379,"7336, 8924, 9577, 11200, 23030"]
["Reactome","R-HSA-5653656","Vesicle-mediated transport",0.9503505072708063,0.9804681205236514,662.0,65.0,119051.05589123868,"125058, 1277, 286, 338, 274, 2890, 7163, 51422, 54453, 83696, 154, 185, 273, 287, 348, 547, 1212, 1278, 1282, 1639, 1956, 2060, 2697, 2700, 2702, 2703, 2810, 4035, 4121, 4625, 5648, 5866, 5867, 6714, 6764, 7474, 8542, 9525, 9685, 10000, 10175, 11037, 22989, 23166, 23216, 25782, 26119, 26153, 27147, 29993, 51112, 51762, 54536, 55330, 57134, 57186, 57533, 60592, 79890, 81035, 81846, 85439, 112574, 117177, 221458"]
["Reactome","R-HSA-977444","GABA B receptor activation",0.9514440873536636,0.9804681205236514,40.0,5.0,186276.45,"107, 2793, 3768, 3773, 196883"]
["Reactome","R-HSA-991365","Activation of GABAB receptors",0.9514440873536636,0.9804681205236514,40.0,5.0,186276.45,"107, 2793, 3768, 3773, 196883"]
["Reactome","R-HSA-425393","Transport of inorganic cations/anions and amino acids/oligopeptides",0.9598114086619187,0.9862700881782644,105.0,12.0,143300.34285714285,"6546, 121260, 1811, 6509, 6510, 6522, 6539, 9056, 10723, 51296, 57419, 124935"]
["Reactome","R-HSA-202430","Translocation of ZAP-70 to Immunological synapse",0.961174367855147,0.98673266063762,17.0,1.0,41395.17647058824,"919"]
["Reactome","R-HSA-3232118","SUMOylation of transcription factors",0.9718267648783117,0.994768440805043,17.0,2.0,175559.41176470587,"6670, 4286"]
["KEGG Pathways","hsa00410","beta-Alanine metabolism",0.9719747260142221,0.9989248813013669,22.0,2.0,103368.77272727272,"1807, 2572"]
["Reactome","R-HSA-5693606","DNA Double Strand Break Response",0.9773063197537235,0.9974352660856232,75.0,5.0,67477.96,"7336, 8924, 9577, 11200, 23030"]
["Reactome","R-HSA-2173788","Downregulation of TGF-beta receptor signaling",0.9789813296178042,0.9974352660856232,26.0,3.0,152474.38461538462,"4088, 5501, 56937"]
["Reactome","R-HSA-5628897","TP53 Regulates Metabolic Genes",0.9801257772633558,0.9976609842012125,83.0,8.0,107887.39759036145,"51422, 57521, 1327, 2810, 10000, 27327, 57690, 64121"]
["KEGG Pathways","hsa05012","Parkinson's disease",0.9841191300225809,0.9989248813013669,114.0,8.0,77591.83333333333,"317, 517, 1327, 2861, 5071, 6390, 7318, 56901"]
["Reactome","R-HSA-442729","CREB phosphorylation through the activation of CaMKII",0.9852671956664535,0.9983895976404846,16.0,2.0,166825.8125,"2903, 2905"]
["Reactome","R-HSA-425397","Transport of vitamins, nucleosides, and related molecules",0.986434312495657,0.9983895976404846,40.0,4.0,122560.7,"2030, 3177, 6579, 28232"]
["Reactome","R-HSA-1236382","Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants",0.9871885091246889,0.9983895976404846,20.0,2.0,139120.6,"1956, 5295"]
["Reactome","R-HSA-1643713","Signaling by EGFR in Cancer",0.9871885091246889,0.9983895976404846,20.0,2.0,139120.6,"1956, 5295"]
["Reactome","R-HSA-5637815","Signaling by Ligand-Responsive EGFR Variants in Cancer",0.9871885091246889,0.9983895976404846,20.0,2.0,139120.6,"1956, 5295"]
["KEGG Pathways","hsa05416","Viral myocarditis",0.9890935913273465,0.9989248813013669,68.0,6.0,139741.57352941178,"3689, 595, 2534, 4625, 4627, 22989"]
["Reactome","R-HSA-2428924","IGF1R signaling cascade",0.9914921636120438,0.9983895976404846,296.0,32.0,149491.7939189189,"2675, 1846, 51422, 57521, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 55437, 64121, 153090"]
["Reactome","R-HSA-2428928","IRS-related events triggered by IGF1R",0.9914921636120438,0.9983895976404846,296.0,32.0,149491.7939189189,"2675, 1846, 51422, 57521, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 55437, 64121, 153090"]
["Reactome","R-HSA-170984","ARMS-mediated activation",0.9933788064176438,0.9983895976404846,247.0,27.0,153999.84615384616,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-428930","Thromboxane signalling through TP receptor",0.9940413994624,0.9983895976404846,23.0,2.0,89237.91304347826,"2793, 10672"]
["Reactome","R-HSA-1169408","ISG15 antiviral mechanism",0.9948826893556532,0.9983895976404846,73.0,6.0,83569.83561643836,"317649, 2317, 4600, 7318, 8021, 23225"]
["Reactome","R-HSA-1169410","Antiviral mechanism by IFN-stimulated genes",0.9948826893556532,0.9983895976404846,73.0,6.0,83569.83561643836,"317649, 2317, 4600, 7318, 8021, 23225"]
["Reactome","R-HSA-211981","Xenobiotics",0.9976996842053236,0.9983895976404846,22.0,2.0,92455.63636363637,"196, 9915"]
["Reactome","R-HSA-5576892","Phase 0 - rapid depolarisation",0.9983895976404846,0.9983895976404846,46.0,6.0,186624.95652173914,"783, 9254, 775, 2256, 55799, 93589"]
["KEGG Pathways","hsa03050","Proteasome",0.9989248813013669,0.9989248813013669,43.0,3.0,70546.69767441861,"3458, 5689, 9861"]
["Reactome","R-HSA-74160","Gene Expression",1.1918029551256326E-7,6.441694972454044E-5,1771.0,86.0,88937.48842461886,"4088, 9612, 4784, 5308, 5915, 23293, 639, 860, 3720, 6095, 10499, 51422, 54971, 55615, 57521, 80139, 374655, 317, 348, 677, 834, 1081, 1327, 1387, 1482, 1653, 1956, 2099, 2101, 2104, 2494, 2810, 4089, 4774, 4781, 4782, 5451, 5457, 5580, 5689, 5914, 5976, 6156, 6228, 6229, 6497, 6874, 7003, 7025, 7027, 7101, 8013, 8021, 8353, 8738, 8812, 9572, 9861, 10000, 10200, 10940, 11103, 11200, 23225, 25885, 25929, 25937, 26155, 27327, 29117, 54790, 56006, 57690, 64121, 79664, 79755, 80205, 80818, 116028, 126375, 196513, 200315, 200424, 285268, 344787, 619279"]
["KEGG Pathways","hsa01100","Metabolic pathways",0.0015828917301882273,0.06489856093771731,1105.0,72.0,124704.47239819005,"6480, 1603, 9945, 5287, 8972, 10170, 29926, 55500, 79623, 125, 216, 229, 272, 411, 445, 517, 525, 528, 549, 622, 1327, 1610, 1621, 1757, 1807, 2180, 2572, 2591, 2651, 2678, 2731, 2762, 3290, 3632, 3706, 3990, 4121, 4842, 4942, 5051, 5214, 5330, 6390, 6472, 7173, 7306, 7941, 8310, 8869, 8877, 8974, 9249, 9514, 10312, 11320, 11343, 23305, 23649, 23761, 25885, 25902, 50487, 50614, 56901, 57134, 57818, 64131, 84532, 90423, 144193, 157506, 221223"]
["Reactome","R-HSA-72203","Processing of Capped Intron-Containing Pre-mRNA",0.0016495540090144052,0.09385094124971431,242.0,2.0,71611.80578512397,"8021, 23225"]
["Reactome","R-HSA-73894","DNA Repair",0.010224716439377874,0.3450081748023326,312.0,12.0,81383.05128205128,"4255, 5890, 7318, 7336, 8924, 9577, 11200, 23030, 25898, 84164, 116028, 378708"]
["Reactome","R-HSA-69278","Cell Cycle, Mitotic",0.01144137235665638,0.3450081748023326,517.0,27.0,95195.33849129594,"8379, 9663, 595, 699, 894, 1063, 1639, 4751, 4926, 5501, 5689, 5925, 7027, 8021, 8353, 9861, 10000, 11064, 23225, 23649, 55722, 55839, 79648, 81565, 95681, 221496, 378708"]
["Reactome","R-HSA-6811442","Intra-Golgi and retrograde Golgi-to-ER traffic",0.014327228039705221,0.4018182373273602,193.0,8.0,116642.11917098446,"547, 1639, 4121, 25782, 26153, 57134, 60592, 221458"]
["Reactome","R-HSA-212436","Generic Transcription Pathway",0.015968518629450777,0.4210236253277144,845.0,56.0,104480.83195266272,"4088, 9612, 5308, 5915, 639, 860, 6095, 10499, 51422, 54971, 55615, 57521, 80139, 374655, 317, 348, 834, 1081, 1327, 1387, 1482, 1956, 2099, 2101, 2104, 2494, 2810, 4089, 5457, 5914, 6497, 6874, 7003, 7025, 7027, 7101, 8013, 8738, 8812, 9572, 10000, 11200, 25937, 26155, 27327, 29117, 57690, 64121, 79755, 80205, 80818, 116028, 126375, 285268, 344787, 619279"]
["Reactome","R-HSA-73857","RNA Polymerase II Transcription",0.019792348103572915,0.48626200681732545,153.0,2.0,57899.294117647056,"6874, 8812"]
["Reactome","R-HSA-71291","Metabolism of amino acids and derivatives",0.02367832075959853,0.5564405378505655,352.0,18.0,101011.5625,"1734, 51582, 445, 549, 1081, 1610, 1621, 2731, 4942, 5689, 6156, 6228, 6229, 6539, 7173, 7306, 9861, 144193"]
["Reactome","R-HSA-1852241","Organelle biogenesis and maintenance",0.02440028475822177,0.5612065494391008,348.0,17.0,90098.9827586207,"83657, 10499, 10891, 51422, 1387, 1639, 2101, 4751, 9572, 11064, 54536, 55722, 64792, 80205, 95681, 117177, 200132"]
["KEGG Pathways","hsa04740","Olfactory transduction",0.026305716380276758,0.254423750456489,380.0,13.0,60744.70789473684,"810, 219952, 5567, 8383, 26496, 26529, 26707, 79324, 219428, 219956, 256892, 346517, 390058"]
["Reactome","R-HSA-72766","Translation",0.02728030185696409,0.5847322357096726,156.0,3.0,61507.6858974359,"6156, 6228, 6229"]
["Reactome","R-HSA-5696398","Nucleotide Excision Repair",0.02744985569873326,0.5847322357096726,111.0,1.0,73954.97297297297,"7336"]
["Reactome","R-HSA-1640170","Cell Cycle",0.03440672659001769,0.6303545882039621,622.0,38.0,98474.94372990353,"8379, 9663, 595, 699, 894, 1063, 1639, 2810, 4751, 4926, 5501, 5689, 5925, 7027, 7336, 8021, 8353, 8924, 9577, 9861, 10000, 11064, 11144, 11200, 23224, 23225, 23345, 23649, 50511, 55355, 55722, 55839, 79648, 81565, 95681, 116028, 221496, 378708"]
["Reactome","R-HSA-72312","rRNA processing",0.03755927391049445,0.6565305849786287,193.0,5.0,62335.538860103625,"6156, 6228, 6229, 10200, 11103"]
["Reactome","R-HSA-8856688","Golgi-to-ER retrograde transport",0.04232863654899592,0.693291759234312,125.0,5.0,122338.952,"547, 1639, 25782, 26153, 221458"]
["Reactome","R-HSA-5696399","Global Genome Nucleotide Excision Repair (GG-NER)",0.043643661338972344,0.6965348225917785,84.0,1.0,84202.69047619047,"7336"]
["Reactome","R-HSA-6802952","Signaling by BRAF and RAF fusions",0.04777473808396715,0.7172846092884513,62.0,2.0,147018.5,"6714, 10018"]
["Reactome","R-HSA-196849","Metabolism of water-soluble vitamins and cofactors",0.05105339478563974,0.7282693313274191,121.0,6.0,127906.31404958677,"143, 5168, 6472, 6513, 25902, 113278"]
["Reactome","R-HSA-6811434","COPI-dependent Golgi-to-ER retrograde traffic",0.05467882186091168,0.7428171887237506,97.0,3.0,103959.9175257732,"547, 26153, 221458"]
["Reactome","R-HSA-5617833","Cilium Assembly",0.056300838616061805,0.7428171887237506,202.0,10.0,91509.82178217822,"83657, 1639, 4751, 11064, 54536, 55722, 64792, 95681, 117177, 200132"]
["Reactome","R-HSA-8868773","rRNA processing in the nucleus and cytosol",0.0563469097829302,0.7428171887237506,183.0,5.0,61017.174863387976,"6156, 6228, 6229, 10200, 11103"]
["Reactome","R-HSA-381753","Olfactory Signaling Pathway",0.05880623135911001,0.752894043662322,377.0,14.0,54966.572944297084,"219952, 8383, 26496, 26529, 26707, 79324, 132112, 219428, 219956, 221035, 256892, 285093, 346517, 390058"]
["Reactome","R-HSA-2132295","MHC class II antigen presentation",0.06026083558703339,0.752894043662322,118.0,4.0,89734.34745762713,"1513, 1514, 1639, 26153"]
["Reactome","R-HSA-199977","ER to Golgi Anterograde Transport",0.062234425302896884,0.752894043662322,149.0,6.0,90098.63087248322,"286, 2890, 83696, 287, 1639, 10175"]
["Reactome","R-HSA-68886","M Phase",0.06349183703986258,0.752894043662322,317.0,16.0,92375.91482649843,"8379, 9663, 699, 1063, 5501, 5689, 5925, 8021, 8353, 9861, 23225, 55839, 79648, 81565, 221496, 378708"]
["Reactome","R-HSA-1428517","The citric acid (TCA) cycle and respiratory electron transport",0.064243124865132,0.752894043662322,155.0,5.0,70198.8,"27109, 517, 1327, 6390, 9123"]
["KEGG Pathways","hsa03008","Ribosome biogenesis in eukaryotes",0.06447646821933269,0.40128714789768266,74.0,1.0,84398.52702702703,"10940"]
["Reactome","R-HSA-2555396","Mitotic Metaphase and Anaphase",0.06518705310503337,0.752894043662322,195.0,10.0,107804.70256410257,"8379, 699, 1063, 5501, 5689, 9861, 55839, 81565, 221496, 378708"]
["Reactome","R-HSA-5663205","Infectious disease",0.06629005499476198,0.7543110468351337,379.0,19.0,80068.89709762533,"1499, 10015, 919, 999, 2060, 2534, 5689, 6156, 6228, 6229, 6416, 6714, 6874, 8021, 8812, 9525, 9844, 9861, 23225"]
["Reactome","R-HSA-68882","Mitotic Anaphase",0.06874532763613832,0.7605234268523102,194.0,10.0,107709.55154639175,"8379, 699, 1063, 5501, 5689, 9861, 55839, 81565, 221496, 378708"]
["Reactome","R-HSA-2871837","FCERI mediated NF-kB activation",0.06886331037039531,0.7605234268523102,81.0,2.0,87224.03703703704,"5689, 9861"]
["Reactome","R-HSA-6791226","Major pathway of rRNA processing in the nucleolus and cytosol",0.07020762170056793,0.7605234268523102,172.0,5.0,62972.61627906977,"6156, 6228, 6229, 10200, 11103"]
["Reactome","R-HSA-2467813","Separation of Sister Chromatids",0.07278839773645664,0.7605234268523102,183.0,9.0,99866.4480874317,"8379, 699, 1063, 5501, 5689, 9861, 55839, 81565, 378708"]
["Reactome","R-HSA-453274","Mitotic G2-G2/M phases",0.08086316600485438,0.8093803930671073,194.0,9.0,80869.86082474227,"1063, 1639, 4751, 4926, 5689, 9861, 11064, 55722, 95681"]
["Reactome","R-HSA-6802957","Oncogenic MAPK signaling",0.08211772398755274,0.8109307211487633,76.0,4.0,144585.51315789475,"6714, 10018, 22821, 153090"]
["Reactome","R-HSA-2408522","Selenoamino acid metabolism",0.08251838975611837,0.8109307211487633,116.0,3.0,70819.74137931035,"6156, 6228, 6229"]
["Reactome","R-HSA-3700989","Transcriptional Regulation by TP53",0.08485748665033854,0.8117347862139892,365.0,23.0,95431.74520547946,"639, 51422, 54971, 55615, 57521, 317, 834, 1327, 1387, 2810, 5457, 6874, 7027, 8738, 8812, 10000, 11200, 26155, 27327, 29117, 57690, 64121, 116028"]
["Reactome","R-HSA-6803157","Antimicrobial peptides",0.08596285186958204,0.8117347862139892,87.0,1.0,50635.29885057471,"1113"]
["Reactome","R-HSA-69275","G2/M Transition",0.08788063220802612,0.8117347862139892,192.0,9.0,80749.66666666667,"1063, 1639, 4751, 4926, 5689, 9861, 11064, 55722, 95681"]
["Reactome","R-HSA-5693532","DNA Double-Strand Break Repair",0.08815625223362941,0.8117347862139892,164.0,7.0,84654.18902439025,"5890, 7336, 8924, 9577, 11200, 23030, 116028"]
["Reactome","R-HSA-5668914","Diseases of metabolism",0.0930641742391695,0.8193755709905436,44.0,1.0,141951.29545454544,"653509"]
["Reactome","R-HSA-69242","S Phase",0.09414693542766428,0.8193755709905436,129.0,5.0,79962.0,"595, 5689, 5925, 9861, 23649"]
["Reactome","R-HSA-2142753","Arachidonic acid metabolism",0.09462714330156409,0.8193755709905436,58.0,1.0,106031.58620689655,"2678"]
["KEGG Pathways","hsa03013","RNA transport",0.09561084850731139,0.49676999263848515,149.0,6.0,92812.31543624161,"5976, 8021, 10940, 23225, 25929, 132430"]
["Reactome","R-HSA-176408","Regulation of APC/C activators between G1/S and early anaphase",0.09984154883196135,0.8193755709905436,79.0,2.0,77820.46835443038,"5689, 9861"]
["KEGG Pathways","hsa05131","Shigellosis",0.09996192941353874,0.4998096470676937,61.0,2.0,152597.1475409836,"9844, 64127"]
["Reactome","R-HSA-72613","Eukaryotic Translation Initiation",0.10297669003645936,0.8193755709905436,119.0,3.0,59749.36974789916,"6156, 6228, 6229"]
["Reactome","R-HSA-72737","Cap-dependent Translation Initiation",0.10297669003645936,0.8193755709905436,119.0,3.0,59749.36974789916,"6156, 6228, 6229"]
["Reactome","R-HSA-611105","Respiratory electron transport",0.10324393763892328,0.8193755709905436,90.0,2.0,65138.444444444445,"1327, 6390"]
["Reactome","R-HSA-399719","Trafficking of AMPA receptors",0.10555480233487538,0.8193755709905436,31.0,1.0,235899.29032258064,"2890"]
["Reactome","R-HSA-399721","Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity",0.10555480233487538,0.8193755709905436,31.0,1.0,235899.29032258064,"2890"]
["Reactome","R-HSA-6807878","COPI-mediated anterograde transport",0.10651998986694479,0.8193755709905436,94.0,3.0,80055.40425531915,"286, 287, 1639"]
["Reactome","R-HSA-162906","HIV Infection",0.11156835884997532,0.8193755709905436,231.0,11.0,78327.05194805194,"10015, 919, 2534, 5689, 6874, 8021, 8812, 9525, 9844, 9861, 23225"]
["Reactome","R-HSA-5685942","HDR through Homologous Recombination (HRR)",0.11184600627118266,0.8193755709905436,67.0,2.0,94061.28358208956,"5890, 116028"]
["Reactome","R-HSA-5693538","Homology Directed Repair",0.11584646035429388,0.8293379049204748,136.0,5.0,74921.80147058824,"5890, 7336, 8924, 9577, 116028"]
["Reactome","R-HSA-69620","Cell Cycle Checkpoints",0.1178357422135287,0.8380291929791087,198.0,9.0,74931.39393939394,"8379, 2810, 5689, 7336, 8924, 9577, 9861, 11200, 116028"]
["Reactome","R-HSA-392499","Metabolism of proteins",0.12080876026998112,0.8466612790849691,1577.0,121.0,115333.12428662016,"4088, 152, 4978, 6480, 9628, 286, 1603, 6477, 6670, 6904, 6934, 7058, 9945, 10417, 79139, 1499, 2890, 4286, 8313, 29926, 54437, 56999, 79623, 79875, 83696, 140766, 170691, 154, 287, 324, 325, 337, 411, 467, 590, 1081, 1368, 1639, 2099, 2155, 2591, 2762, 2779, 2793, 3313, 3484, 3485, 3489, 3952, 4086, 4089, 4121, 4312, 4585, 5067, 5069, 5071, 5080, 5689, 5867, 5972, 6156, 6228, 6229, 6653, 7057, 7187, 7941, 8021, 8073, 8353, 8737, 8869, 8877, 8924, 9215, 9314, 9509, 9577, 9736, 9804, 9861, 10106, 10130, 10175, 11047, 11096, 11320, 22901, 22921, 23225, 23252, 50614, 50863, 51611, 51762, 54507, 54536, 57134, 57188, 57332, 64127, 64377, 80731, 83729, 84628, 90865, 146760, 148789, 161357, 170692, 219333, 221395, 221937, 253827, 254013, 256281, 338596, 340075, 349667, 653509"]
["KEGG Pathways","hsa00561","Glycerolipid metabolism",0.12161863399781958,0.5540404437678448,50.0,2.0,150737.94,"3990, 11343"]
["Reactome","R-HSA-72202","Transport of Mature Transcript to Cytoplasm",0.12198944453786448,0.8466612790849691,82.0,2.0,68302.70731707317,"8021, 23225"]
["Reactome","R-HSA-68877","Mitotic Prometaphase",0.1231207796740541,0.8466612790849691,128.0,7.0,118781.625,"8379, 699, 1063, 5501, 55839, 81565, 378708"]
["KEGG Pathways","hsa00280","Valine, leucine and isoleucine degradation",0.12742250551340342,0.5557790134095256,44.0,1.0,120547.04545454546,"549"]
["Reactome","R-HSA-6788656","Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism",0.12902102043307023,0.8466612790849691,44.0,1.0,117810.27272727272,"144193"]
["Reactome","R-HSA-202424","Downstream TCR signaling",0.12974759605109137,0.8466612790849691,95.0,4.0,100863.1052631579,"919, 5295, 5689, 9861"]
["Reactome","R-HSA-72706","GTP hydrolysis and joining of the 60S ribosomal subunit",0.13074143991450465,0.8466612790849691,112.0,3.0,59897.357142857145,"6156, 6228, 6229"]
["Reactome","R-HSA-1799339","SRP-dependent cotranslational protein targeting to membrane",0.1324501759300796,0.8466612790849691,112.0,3.0,59712.642857142855,"6156, 6228, 6229"]
["Reactome","R-HSA-429914","Deadenylation-dependent mRNA decay",0.1329347105936376,0.8466612790849691,53.0,1.0,74901.71698113208,"196513"]
["Reactome","R-HSA-69306","DNA Replication",0.13302400271697284,0.8466612790849691,108.0,4.0,87094.50925925926,"5689, 5925, 9861, 23649"]
["KEGG Pathways","hsa00310","Lysine degradation",0.13311950564605685,0.5630521793002792,44.0,1.0,128293.13636363637,"5352"]
["Reactome","R-HSA-156827","L13a-mediated translational silencing of Ceruloplasmin expression",0.13324551450622613,0.8466612790849691,111.0,3.0,60336.55855855856,"6156, 6228, 6229"]
["Reactome","R-HSA-162587","HIV Life Cycle",0.1349185473955209,0.8466612790849691,148.0,6.0,76285.83108108108,"10015, 6874, 8021, 8812, 9525, 23225"]
["Reactome","R-HSA-157579","Telomere Maintenance",0.13518074511697772,0.8466612790849691,77.0,1.0,63481.03896103896,"23649"]
["Reactome","R-HSA-1169091","Activation of NF-kappaB in B cells",0.1353761319065303,0.8466612790849691,67.0,2.0,86314.25373134328,"5689, 9861"]
["Reactome","R-HSA-5685938","HDR through Single Strand Annealing (SSA)",0.13650093734804133,0.8466612790849691,38.0,1.0,122597.57894736843,"116028"]
["Reactome","R-HSA-174184","Cdc20:Phospho-APC/C mediated degradation of Cyclin A",0.14027233053272653,0.8466612790849691,71.0,2.0,77872.07042253521,"5689, 9861"]
["Reactome","R-HSA-168254","Influenza Infection",0.1403960914689352,0.8466612790849691,153.0,5.0,61220.75816993464,"6156, 6228, 6229, 8021, 23225"]
["Reactome","R-HSA-264876","Insulin processing",0.1437523046217815,0.8495467512663443,28.0,1.0,192360.9642857143,"54536"]
["Reactome","R-HSA-6796648","TP53 Regulates Transcription of DNA Repair Genes",0.14468253648473903,0.8495467512663443,66.0,1.0,55766.28787878788,"8812"]
["Reactome","R-HSA-5693567","HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)",0.14921541650437917,0.8495467512663443,130.0,5.0,74057.74615384615,"5890, 7336, 8924, 9577, 116028"]
["Reactome","R-HSA-446203","Asparagine N-linked glycosylation",0.1510120998355671,0.8495467512663443,299.0,20.0,130608.07692307692,"6480, 286, 1603, 9945, 79139, 2890, 29926, 83696, 287, 1081, 1639, 2762, 4121, 8869, 10175, 11320, 57134, 64377, 256281, 338596"]
["KEGG Pathways","hsa00980","Metabolism of xenobiotics by cytochrome P450",0.15377532357069282,0.5837766913331857,70.0,2.0,68243.41428571429,"125, 4258"]
["Reactome","R-HSA-6811440","Retrograde transport at the Trans-Golgi-Network",0.15478021346206108,0.8495467512663443,48.0,1.0,78074.54166666667,"60592"]
["Reactome","R-HSA-6802946","Signaling by moderate kinase activity BRAF mutants",0.15524469842148136,0.8495467512663443,40.0,1.0,107004.575,"6714"]
["Reactome","R-HSA-6802955","Paradoxical activation of RAF signaling by kinase inactive BRAF",0.15524469842148136,0.8495467512663443,40.0,1.0,107004.575,"6714"]
["Reactome","R-HSA-68874","M/G1 Transition",0.15582016772300863,0.8495467512663443,85.0,3.0,92327.38823529411,"5689, 9861, 23649"]
["Reactome","R-HSA-69002","DNA Replication Pre-Initiation",0.15582016772300863,0.8495467512663443,85.0,3.0,92327.38823529411,"5689, 9861, 23649"]
["Reactome","R-HSA-76005","Response to elevated platelet cytosolic Ca2+",0.15605714477348903,0.8495467512663443,129.0,8.0,155639.86821705426,"7123, 7424, 1, 1675, 7057, 7078, 51097, 54863"]
["Reactome","R-HSA-674695","RNA Polymerase II Pre-transcription Events",0.1581076700457607,0.8495467512663443,85.0,2.0,54134.7294117647,"6874, 8812"]
["Reactome","R-HSA-5696395","Formation of Incision Complex in GG-NER",0.15982520592607624,0.8495467512663443,43.0,1.0,94815.58139534884,"7336"]
["Reactome","R-HSA-174143","APC/C-mediated degradation of cell cycle proteins",0.16332272512414986,0.8495467512663443,85.0,3.0,76477.44705882353,"4751, 5689, 9861"]
["Reactome","R-HSA-453276","Regulation of mitotic cell cycle",0.16332272512414986,0.8495467512663443,85.0,3.0,76477.44705882353,"4751, 5689, 9861"]
["Reactome","R-HSA-75893","TNF signaling",0.16397964424631367,0.8495467512663443,43.0,1.0,93214.02325581395,"8737"]
["KEGG Pathways","hsa00620","Pyruvate metabolism",0.1652162832877456,0.5986716670165014,40.0,1.0,119216.2,"84532"]
["Reactome","R-HSA-5674135","MAP2K and MAPK activation",0.16705577603427513,0.8558639520997697,40.0,1.0,103229.325,"6714"]
["KEGG Pathways","hsa04141","Protein processing in endoplasmic reticulum",0.17035644073915562,0.5987069443078807,165.0,9.0,110940.97575757575,"1603, 79139, 3301, 4121, 5034, 5071, 10130, 57134, 80700"]
["Reactome","R-HSA-2500257","Resolution of Sister Chromatid Cohesion",0.17096260873930477,0.8593188296301203,120.0,7.0,117338.25833333333,"8379, 699, 1063, 5501, 55839, 81565, 378708"]
["Reactome","R-HSA-159236","Transport of Mature mRNA derived from an Intron-Containing Transcript",0.17155266989811135,0.8593188296301203,71.0,2.0,70813.2957746479,"8021, 23225"]
["Reactome","R-HSA-6790901","rRNA modification in the nucleus and cytosol",0.17508002651634944,0.8593188296301203,60.0,1.0,54203.38333333333,"11103"]
["KEGG Pathways","hsa00500","Starch and sucrose metabolism",0.17523130077303828,0.5987069443078807,52.0,2.0,185863.0,"8972, 57818"]
["Reactome","R-HSA-1234176","Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha",0.17706484988294985,0.8593188296301203,66.0,2.0,77815.0303030303,"5689, 9861"]
["Reactome","R-HSA-1483166","Synthesis of PA",0.17891755519525493,0.8593188296301203,33.0,1.0,177433.78787878787,"55326"]
["Reactome","R-HSA-5620920","Cargo trafficking to the periciliary membrane",0.1813660863248759,0.8593188296301203,52.0,2.0,110223.98076923077,"54536, 117177"]
["Reactome","R-HSA-6802948","Signaling by high-kinase activity BRAF mutants",0.1830205499723451,0.8593188296301203,36.0,1.0,110750.05555555556,"6714"]
["KEGG Pathways","hsa00564","Glycerophospholipid metabolism",0.18385357843774663,0.6137930762997134,79.0,4.0,141659.49367088606,"55500, 3931, 23761, 50487"]
["Reactome","R-HSA-8852276","The role of GTSE1 in G2/M progression after G2 checkpoint",0.1850649324403391,0.8593188296301203,77.0,2.0,56449.01298701299,"5689, 9861"]
["Reactome","R-HSA-204005","COPII (Coat Protein 2) Mediated Vesicle Transport",0.18554192238653622,0.8593188296301203,70.0,3.0,98709.82857142857,"2890, 83696, 10175"]
["KEGG Pathways","hsa00640","Propanoate metabolism",0.1899720777492462,0.6137930762997134,32.0,1.0,139453.625,"84532"]
["KEGG Pathways","hsa00140","Steroid hormone biosynthesis",0.1916232043082032,0.6137930762997134,55.0,2.0,93307.21818181819,"3290, 6716"]
["Reactome","R-HSA-72306","tRNA processing",0.19299693618402838,0.8593188296301203,106.0,4.0,71634.88679245283,"1653, 8021, 10940, 23225"]
["Reactome","R-HSA-5250941","Negative epigenetic regulation of rRNA expression",0.19407233672906973,0.8593188296301203,105.0,2.0,43365.09523809524,"8353, 25885"]
["Reactome","R-HSA-174178","APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1",0.19425724595629656,0.8593188296301203,71.0,2.0,62853.281690140844,"5689, 9861"]
["Reactome","R-HSA-168255","Influenza Life Cycle",0.19437854994583678,0.8593188296301203,142.0,5.0,62061.64788732395,"6156, 6228, 6229, 8021, 23225"]
["Reactome","R-HSA-72689","Formation of a pool of free 40S subunits",0.1965883954968775,0.8593188296301203,102.0,3.0,59044.470588235294,"6156, 6228, 6229"]
["Reactome","R-HSA-2990846","SUMOylation",0.1967367759188582,0.8593188296301203,108.0,6.0,102277.52777777778,"6670, 4286, 8021, 8924, 23225, 57332"]
["Reactome","R-HSA-70614","Amino acid synthesis and interconversion (transamination)",0.1969999810731086,0.8593188296301203,30.0,1.0,166961.1,"4942"]
["Reactome","R-HSA-212165","Epigenetic regulation of gene expression",0.19758171152094514,0.8593188296301203,145.0,5.0,63886.262068965516,"3720, 8353, 25885, 54790, 200424"]
["Reactome","R-HSA-382556","ABC-family proteins mediated transport",0.2004103593004904,0.8593188296301203,105.0,5.0,98164.14285714286,"79139, 5244, 5689, 9861, 23460"]
["Reactome","R-HSA-114608","Platelet degranulation ",0.20272606281604125,0.8593188296301203,124.0,8.0,156702.16129032258,"7123, 7424, 1, 1675, 7057, 7078, 51097, 54863"]
["Reactome","R-HSA-68867","Assembly of the pre-replicative complex",0.20396182780880256,0.8593188296301203,68.0,2.0,65194.92647058824,"5689, 9861"]
["Reactome","R-HSA-70326","Glucose metabolism",0.20463405177693436,0.8593188296301203,80.0,4.0,132742.9375,"5257, 229, 5214, 5567"]
["Reactome","R-HSA-428157","Sphingolipid metabolism",0.20500436709149045,0.8593188296301203,87.0,5.0,125236.89655172414,"411, 1455, 8877, 22901, 340075"]
["Reactome","R-HSA-73864","RNA Polymerase I Transcription",0.20566156454407025,0.8593188296301203,107.0,2.0,40791.0,"8353, 25885"]
["Reactome","R-HSA-1655829","Regulation of cholesterol biosynthesis by SREBP (SREBF)",0.2059907037446681,0.8593188296301203,55.0,3.0,138974.5090909091,"10499, 1387, 80205"]
["Reactome","R-HSA-167172","Transcription of the HIV genome",0.2060283725970774,0.8593188296301203,74.0,2.0,60151.12162162162,"6874, 8812"]
["Reactome","R-HSA-211859","Biological oxidations",0.20666840377191456,0.8593188296301203,216.0,13.0,90410.70370370371,"10499, 125, 196, 216, 2326, 2678, 4258, 6817, 6819, 9915, 66002, 84532, 92292"]
["Reactome","R-HSA-390466","Chaperonin-mediated protein folding",0.20693424337628905,0.8593188296301203,97.0,4.0,79877.71134020618,"9628, 2779, 2793, 8877"]
["Reactome","R-HSA-112382","Formation of RNA Pol II elongation complex ",0.20936304451217785,0.8593188296301203,62.0,1.0,46010.66129032258,"8812"]
["Reactome","R-HSA-75955","RNA Polymerase II Transcription Elongation",0.20936304451217785,0.8593188296301203,62.0,1.0,46010.66129032258,"8812"]
["Reactome","R-HSA-432720","Lysosome Vesicle Biogenesis",0.2112781815115637,0.8593188296301203,36.0,1.0,109150.41666666667,"1212"]
["Reactome","R-HSA-156580","Phase II conjugation",0.21400581213982225,0.8593188296301203,104.0,5.0,92459.93269230769,"2678, 4258, 6817, 6819, 92292"]
["Reactome","R-HSA-427413","NoRC negatively regulates rRNA expression",0.21401265674472025,0.8593188296301203,102.0,2.0,43298.490196078434,"8353, 25885"]
["Reactome","R-HSA-445989","TAK1 activates NFkB by phosphorylation and activation of IKKs complex",0.21460871296058673,0.8593188296301203,33.0,1.0,124793.66666666667,"64127"]
["Reactome","R-HSA-453279","Mitotic G1-G1/S phases",0.21659028017003978,0.8593188296301203,142.0,8.0,97438.1690140845,"595, 894, 5689, 5925, 7027, 9861, 10000, 23649"]
["Reactome","R-HSA-174154","APC/C:Cdc20 mediated degradation of Securin",0.21854594332189375,0.8593188296301203,66.0,2.0,65676.39393939394,"5689, 9861"]
["Reactome","R-HSA-69239","Synthesis of DNA",0.21884722643878643,0.8593188296301203,100.0,4.0,70926.37,"5689, 5925, 9861, 23649"]
["Reactome","R-HSA-73854","RNA Polymerase I Promoter Clearance",0.2192737554130138,0.8593188296301203,105.0,2.0,40796.52380952381,"8353, 25885"]
["Reactome","R-HSA-196807","Nicotinate metabolism",0.21958478071720766,0.8593188296301203,29.0,1.0,140417.10344827586,"143"]
["Reactome","R-HSA-1660661","Sphingolipid de novo biosynthesis",0.21966827250877158,0.8593188296301203,43.0,2.0,126587.09302325582,"1455, 8877"]
["Reactome","R-HSA-597592","Post-translational protein modification",0.22161194446139054,0.8593188296301203,1026.0,84.0,130478.00194931774,"4088, 4978, 6480, 286, 1603, 6670, 7058, 9945, 10417, 79139, 2890, 4286, 8313, 29926, 54437, 56999, 79623, 79875, 83696, 140766, 170691, 154, 287, 324, 411, 1081, 1368, 1639, 2099, 2155, 2591, 2762, 4086, 4089, 4121, 4585, 5067, 5071, 5689, 5867, 7057, 7187, 8021, 8073, 8737, 8869, 8924, 9215, 9509, 9577, 9736, 9804, 9861, 10175, 11047, 11096, 11320, 22901, 23225, 23252, 50614, 50863, 51611, 51762, 54507, 57134, 57188, 57332, 64127, 64377, 80731, 84628, 90865, 146760, 148789, 161357, 170692, 219333, 221937, 254013, 256281, 338596, 340075, 349667"]
["Reactome","R-HSA-199992","trans-Golgi Network Vesicle Budding",0.22397333400364214,0.8593188296301203,73.0,4.0,112935.24657534246,"7163, 1212, 9685, 55330"]
["Reactome","R-HSA-421837","Clathrin derived vesicle budding",0.22397333400364214,0.8593188296301203,73.0,4.0,112935.24657534246,"7163, 1212, 9685, 55330"]
["Reactome","R-HSA-163200","Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.",0.22525299963233578,0.8593188296301203,111.0,4.0,62203.207207207204,"27109, 517, 1327, 6390"]
["Reactome","R-HSA-983189","Kinesins",0.2273715802668597,0.8593188296301203,58.0,3.0,126080.22413793103,"547, 26153, 221458"]
["Reactome","R-HSA-167161","HIV Transcription Initiation",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-167162","RNA Polymerase II HIV Promoter Escape",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-73776","RNA Polymerase II Promoter Escape",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-73779","RNA Polymerase II Transcription Pre-Initiation And Promoter Opening",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-75953","RNA Polymerase II Transcription Initiation",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-76042","RNA Polymerase II Transcription Initiation And Promoter Clearance",0.22829545103280108,0.8593188296301203,47.0,1.0,64110.8085106383,"6874"]
["Reactome","R-HSA-432722","Golgi Associated Vesicle Biogenesis",0.23483006642681753,0.8661182887319608,57.0,3.0,115189.54385964913,"7163, 9685, 55330"]
["Reactome","R-HSA-1234174","Regulation of Hypoxia-inducible Factor (HIF) by oxygen",0.23674279428862388,0.8661182887319608,76.0,3.0,77504.6447368421,"1387, 5689, 9861"]
["Reactome","R-HSA-2262749","Cellular response to hypoxia",0.23674279428862388,0.8661182887319608,76.0,3.0,77504.6447368421,"1387, 5689, 9861"]
["Reactome","R-HSA-73887","Death Receptor Signalling",0.23901550151385564,0.8661182887319608,50.0,2.0,93095.78,"8743, 8737"]
["Reactome","R-HSA-2559582","Senescence-Associated Secretory Phenotype (SASP)",0.23923096873322386,0.8661182887319608,104.0,3.0,71463.01923076923,"3490, 6196, 8353"]
["Reactome","R-HSA-162599","Late Phase of HIV Life Cycle",0.24088773275146722,0.8661182887319608,135.0,6.0,73947.04444444444,"10015, 6874, 8021, 8812, 9525, 23225"]
["Reactome","R-HSA-72662","Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S",0.2434729729384415,0.8661182887319608,59.0,2.0,79561.49152542373,"6228, 6229"]
["Reactome","R-HSA-5689603","UCH proteinases",0.24478757431854778,0.8661182887319608,99.0,4.0,73444.53535353535,"5689, 9861, 11047, 221937"]
["Reactome","R-HSA-176814","Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins",0.24781877933575763,0.8661182887319608,75.0,3.0,76772.49333333333,"4751, 5689, 9861"]
["Reactome","R-HSA-73762","RNA Polymerase I Transcription Initiation",0.25060275110007146,0.8661182887319608,48.0,1.0,57999.708333333336,"25885"]
["Reactome","R-HSA-68962","Activation of the pre-replicative complex",0.2507522276973159,0.8661182887319608,32.0,1.0,140091.5625,"23649"]
["KEGG Pathways","hsa00983","Drug metabolism - other enzymes",0.25176866252561014,0.7127317528110876,51.0,2.0,90118.43137254902,"1807, 221223"]
["KEGG Pathways","hsa00020","Citrate cycle (TCA cycle)",0.25380203880589947,0.7127317528110876,30.0,1.0,169309.73333333334,"6390"]
["Reactome","R-HSA-72649","Translation initiation complex formation",0.2547582228994971,0.8661182887319608,58.0,2.0,79736.4827586207,"6228, 6229"]
["Reactome","R-HSA-1483206","Glycerophospholipid biosynthesis",0.25502259762860696,0.8661182887319608,125.0,8.0,119334.888,"9663, 55500, 590, 1757, 11343, 23761, 50487, 55326"]
["Reactome","R-HSA-445095","Interaction between L1 and Ankyrins",0.255114070156667,0.8661182887319608,31.0,2.0,176319.2258064516,"286, 287"]
["Reactome","R-HSA-176409","APC/C:Cdc20 mediated degradation of mitotic proteins",0.2551874902163836,0.8661182887319608,74.0,3.0,77322.58108108108,"4751, 5689, 9861"]
["Reactome","R-HSA-174084","Autodegradation of Cdh1 by Cdh1:APC/C",0.25619314093017964,0.8661182887319608,62.0,2.0,65663.82258064517,"5689, 9861"]
["Reactome","R-HSA-6783310","Fanconi Anemia Pathway",0.25662626922357856,0.8661182887319608,38.0,1.0,77808.42105263157,"378708"]
["Reactome","R-HSA-3108214","SUMOylation of DNA damage response and repair proteins",0.25761306910603365,0.8661182887319608,77.0,4.0,91691.74025974025,"8021, 8924, 23225, 57332"]
["Reactome","R-HSA-3108232","SUMO E3 ligases SUMOylate target proteins",0.25888740929971027,0.8661182887319608,102.0,6.0,102713.75490196078,"6670, 4286, 8021, 8924, 23225, 57332"]
["Reactome","R-HSA-5693579","Homologous DNA Pairing and Strand Exchange",0.2589675268395368,0.8661182887319608,43.0,2.0,108464.06976744186,"5890, 116028"]
["Reactome","R-HSA-5250913","Positive epigenetic regulation of rRNA expression",0.2598078757089314,0.8661182887319608,103.0,2.0,34119.25242718447,"8353, 25885"]
["Reactome","R-HSA-72702","Ribosomal scanning and start codon recognition",0.26044114084112785,0.8661182887319608,58.0,2.0,78839.13793103448,"6228, 6229"]
["Reactome","R-HSA-168273","Influenza Viral RNA Transcription and Replication",0.2614374127048175,0.8661182887319608,133.0,5.0,62059.47368421053,"6156, 6228, 6229, 8021, 23225"]
["Reactome","R-HSA-5633007","Regulation of TP53 Activity",0.26274474416555116,0.8661182887319608,162.0,11.0,101500.74074074074,"639, 51422, 54971, 55615, 5457, 6874, 10000, 11200, 26155, 29117, 116028"]
["Reactome","R-HSA-5654738","Signaling by FGFR2",0.2629551074772578,0.8661182887319608,74.0,4.0,136726.4054054054,"2252, 2263, 5295, 6714"]
["KEGG Pathways","hsa00982","Drug metabolism - cytochrome P450",0.262978390264626,0.7188076000566443,72.0,3.0,74444.65277777778,"125, 2326, 4258"]
["Reactome","R-HSA-69481","G2/M Checkpoints",0.26434813018043335,0.8661182887319608,167.0,8.0,67430.2634730539,"2810, 5689, 7336, 8924, 9577, 9861, 11200, 116028"]
["Reactome","R-HSA-6811438","Intra-Golgi traffic",0.26465598669867,0.8661182887319608,44.0,2.0,116731.65909090909,"4121, 57134"]
["Reactome","R-HSA-6811436","COPI-independent Golgi-to-ER retrograde traffic",0.2672930359446219,0.8676990145829918,45.0,2.0,132790.8,"1639, 25782"]
["Reactome","R-HSA-179419","APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint",0.26956931419666136,0.8694868882557586,72.0,3.0,78573.13888888889,"4751, 5689, 9861"]
["KEGG Pathways","hsa03030","DNA replication",0.26978119710121323,0.7276992816545883,36.0,1.0,123431.02777777778,"23649"]
["Reactome","R-HSA-6807004","Negative regulation of MET activity",0.2718682311256057,0.8694868882557586,21.0,1.0,178888.38095238095,"2060"]
["Reactome","R-HSA-5693616","Presynaptic phase of homologous DNA pairing and strand exchange",0.27598048804654474,0.8694868882557586,40.0,2.0,115091.85,"5890, 116028"]
["Reactome","R-HSA-3214815","HDACs deacetylate histones",0.27767276553820647,0.8694868882557586,88.0,2.0,53475.14772727273,"9612, 8353"]
["Reactome","R-HSA-390471","Association of TriC/CCT with target proteins during biosynthesis",0.2786442354220092,0.8694868882557586,40.0,1.0,68673.975,"8877"]
["Reactome","R-HSA-913709","O-linked glycosylation of mucins",0.2791044867944017,0.8694868882557586,61.0,5.0,189459.80327868852,"6480, 79623, 2591, 4585, 50614"]
["Reactome","R-HSA-6791312","TP53 Regulates Transcription of Cell Cycle Genes",0.2808989175920793,0.8694881317062018,49.0,2.0,88258.26530612246,"2810, 7027"]
["Reactome","R-HSA-68827","CDT1 association with the CDC6:ORC:origin complex",0.2827655328060508,0.8708533930579514,59.0,2.0,66816.08474576271,"5689, 9861"]
["Reactome","R-HSA-6804756","Regulation of TP53 Activity through Phosphorylation",0.2837793667011528,0.8714928846703015,93.0,5.0,87669.89247311828,"51422, 6874, 11200, 26155, 116028"]
["KEGG Pathways","hsa03015","mRNA surveillance pathway",0.2866403695348853,0.7317470827705681,82.0,5.0,143255.48780487804,"23293, 5521, 5522, 5976, 132430"]
["Reactome","R-HSA-8873719","RAB geranylgeranylation",0.2886914047828603,0.8815689507634802,64.0,3.0,87806.40625,"5867, 8073, 51762"]
["Reactome","R-HSA-391251","Protein folding",0.2907617433083027,0.8832204779267748,103.0,5.0,81230.84466019417,"9628, 6904, 2779, 2793, 8877"]
["Reactome","R-HSA-532668","N-glycan trimming in the ER and Calnexin/Calreticulin cycle",0.2908663183551636,0.8832204779267748,35.0,1.0,123078.0,"79139"]
["Reactome","R-HSA-416993","Trafficking of GluR2-containing AMPA receptors",0.2926243211093401,0.8860697230229598,16.0,1.0,325816.1875,"2890"]
["Reactome","R-HSA-71406","Pyruvate metabolism and Citric Acid (TCA) cycle",0.2948624746777526,0.8877582377167847,48.0,2.0,85891.66666666667,"6390, 9123"]
["Reactome","R-HSA-72764","Eukaryotic Translation Termination",0.2980433892880909,0.8877582377167847,93.0,3.0,56865.87096774193,"6156, 6228, 6229"]
["Reactome","R-HSA-73886","Chromosome Maintenance",0.29978143811020835,0.8877582377167847,104.0,4.0,77597.0,"23649, 55355, 55839, 378708"]
["KEGG Pathways","hsa00600","Sphingolipid metabolism",0.30051069636727984,0.7317470827705681,40.0,2.0,146757.8,"8877, 9514"]
["Reactome","R-HSA-6802949","Signaling by RAS mutants",0.30145742767494255,0.8877582377167847,51.0,3.0,118197.90196078431,"6714, 22821, 153090"]
["KEGG Pathways","hsa03018","RNA degradation",0.30347097695523506,0.7317470827705681,71.0,4.0,129624.01408450704,"3313, 10200, 132430, 196513"]
["Reactome","R-HSA-5693607","Processing of DNA double-strand break ends",0.30466586274047386,0.8901183719525737,97.0,4.0,65649.30927835051,"7336, 8924, 9577, 116028"]
["Reactome","R-HSA-373760","L1CAM interactions",0.30747607362793855,0.8911152022672992,118.0,11.0,172012.43220338982,"286, 287, 1808, 1956, 2260, 6196, 6714, 7410, 8828, 8829, 57698"]
["Reactome","R-HSA-6798695","Neutrophil degranulation",0.30748008366855006,0.8911152022672992,473.0,32.0,84516.6934460888,"3689, 7077, 8972, 23250, 121260, 1, 272, 317, 411, 718, 965, 1675, 3916, 3958, 4973, 5328, 5580, 5689, 6286, 6518, 9145, 9861, 10312, 10493, 10875, 23218, 53831, 57020, 79895, 84766, 150372, 100616211"]
["KEGG Pathways","hsa00601","Glycosphingolipid biosynthesis - lacto and neolacto series",0.31027305769718694,0.7317470827705681,26.0,1.0,172696.11538461538,"2651"]
["Reactome","R-HSA-5362768","Hh mutants that don't undergo autocatalytic processing are degraded by ERAD",0.3142631748338726,0.8987261693000432,56.0,2.0,99096.05357142857,"5689, 9861"]
["Reactome","R-HSA-400685","Sema4D in semaphorin signaling",0.3153791474880054,0.8995378850515404,27.0,1.0,155349.03703703705,"4627"]
["KEGG Pathways","hsa03440","Homologous recombination",0.31595228489307303,0.7317470827705681,28.0,1.0,145375.07142857142,"5890"]
["KEGG Pathways","hsa04146","Peroxisome",0.3163897006447843,0.7317470827705681,78.0,4.0,103381.01282051283,"1610, 2180, 8310, 23305"]
["Reactome","R-HSA-69304","Regulation of DNA replication",0.3176761454906475,0.8999192639867082,76.0,3.0,63811.85526315789,"5689, 5925, 9861"]
["Reactome","R-HSA-8854050","FBXL7 down-regulates AURKA during mitotic entry and in early mitosis",0.3181977417335117,0.8999192639867082,55.0,2.0,73335.47272727273,"5689, 9861"]
["Reactome","R-HSA-2565942","Regulation of PLK1 Activity at G2/M Transition",0.3189761610116237,0.8999192639867082,88.0,5.0,88270.96590909091,"1639, 4751, 11064, 55722, 95681"]
["KEGG Pathways","hsa00340","Histidine metabolism",0.3196996649699901,0.7317470827705681,29.0,1.0,108354.4827586207,"144193"]
["Reactome","R-HSA-73893","DNA Damage Bypass",0.31994957951930403,0.8999192639867082,50.0,2.0,77139.28,"7318, 25898"]
["KEGG Pathways","hsa04130","SNARE interactions in vesicular transport",0.32004048978459515,0.7317470827705681,34.0,1.0,73767.44117647059,"8676"]
["Reactome","R-HSA-425410","Metal ion SLC transporters",0.3205109883702267,0.8999192639867082,25.0,1.0,162667.28,"57181"]
["KEGG Pathways","hsa04640","Hematopoietic cell lineage",0.3212548168261031,0.7317470827705681,85.0,5.0,104771.1294117647,"3655, 1435, 3553, 7066, 7173"]
["Reactome","R-HSA-162909","Host Interactions of HIV factors",0.3271550457736704,0.9045326487504024,131.0,7.0,77489.06870229008,"919, 2534, 5689, 8021, 9844, 9861, 23225"]
["Reactome","R-HSA-5654693","FRS-mediated FGFR1 signaling",0.32766415900297785,0.9045326487504024,23.0,1.0,128401.65217391304,"2260"]
["Reactome","R-HSA-5357956","TNFR1-induced NFkappaB signaling pathway",0.329376645873329,0.9045326487504024,30.0,1.0,93243.56666666667,"8737"]
["Reactome","R-HSA-450408","AUF1 (hnRNP D0) binds and destabilizes mRNA",0.3299327368327341,0.9045326487504024,55.0,2.0,70212.25454545455,"5689, 9861"]
["Reactome","R-HSA-69190","DNA strand elongation",0.33520254332805804,0.9045326487504024,32.0,1.0,83566.84375,"23649"]
["Reactome","R-HSA-975298","Ligand-gated ion channel transport",0.3362536188487068,0.9045326487504024,26.0,2.0,203521.88461538462,"2562, 2741"]
["Reactome","R-HSA-5656169","Termination of translesion DNA synthesis",0.3375857342039267,0.9045326487504024,34.0,1.0,72674.79411764706,"7318"]
["KEGG Pathways","hsa05340","Primary immunodeficiency",0.33904222799654093,0.7473511477343106,35.0,1.0,109844.31428571428,"29851"]
["Reactome","R-HSA-180786","Extension of Telomeres",0.33934457046271876,0.9045326487504024,30.0,1.0,90665.63333333333,"23649"]
["Reactome","R-HSA-167152","Formation of HIV elongation complex in the absence of HIV Tat",0.3394023614062372,0.9045326487504024,49.0,1.0,44807.897959183676,"8812"]
["Reactome","R-HSA-2408557","Selenocysteine synthesis",0.339580193730804,0.9045326487504024,92.0,3.0,54177.77173913043,"6156, 6228, 6229"]
["Reactome","R-HSA-174113","SCF-beta-TrCP mediated degradation of Emi1",0.34052435923661234,0.9045326487504024,55.0,2.0,65829.2,"5689, 9861"]
["Reactome","R-HSA-156842","Eukaryotic Translation Elongation",0.34139622635537853,0.9045326487504024,93.0,3.0,53574.17204301075,"6156, 6228, 6229"]
["Reactome","R-HSA-72695","Formation of the ternary complex, and subsequently, the 43S complex",0.34233705172052914,0.9048077088261418,52.0,2.0,79876.11538461539,"6228, 6229"]
["Reactome","R-HSA-196854","Metabolism of vitamins and cofactors",0.3461482818844501,0.9090328958135842,170.0,14.0,139938.0,"338, 2817, 143, 337, 348, 4035, 5168, 5947, 6382, 6472, 6513, 25902, 113278, 375790"]
["Reactome","R-HSA-192823","Viral mRNA Translation",0.3481475288983471,0.9090328958135842,89.0,3.0,56345.988764044945,"6156, 6228, 6229"]
["Reactome","R-HSA-450302","activated TAK1 mediates p38 MAPK activation",0.3503160152820397,0.9090328958135842,24.0,1.0,134060.41666666666,"64127"]
["Reactome","R-HSA-211000","Gene Silencing by RNA",0.3506739452875649,0.9090328958135842,131.0,5.0,62088.87786259542,"8021, 8353, 23225, 27327, 57690"]
["Reactome","R-HSA-983168","Antigen processing: Ubiquitination & Proteasome degradation",0.35150217729455,0.9090328958135842,306.0,25.0,121834.00326797385,"80176, 6477, 29116, 5071, 5689, 7318, 7336, 7704, 8452, 8924, 8925, 9021, 9861, 10422, 22954, 25897, 25898, 26259, 55521, 55819, 84541, 84676, 84708, 92369, 144699"]
["KEGG Pathways","hsa04612","Antigen processing and presentation",0.3515367055956717,0.7666491983735394,68.0,2.0,45372.867647058825,"1514, 3458"]
["Reactome","R-HSA-112387","Elongation arrest and recovery",0.3520651575832261,0.9090328958135842,50.0,1.0,37802.34,"8812"]
["Reactome","R-HSA-2262752","Cellular responses to stress",0.352154625482177,0.9090328958135842,441.0,29.0,86654.7052154195,"3281, 51422, 57521, 60673, 1387, 2114, 2878, 3005, 3313, 3490, 4688, 5034, 5689, 5925, 6196, 6416, 7027, 8021, 8091, 8353, 9861, 23225, 26100, 26353, 27327, 57332, 57690, 64121, 116835"]
["Reactome","R-HSA-1187000","Fertilization",0.3544749870938672,0.9090328958135842,26.0,1.0,137087.15384615384,"57829"]
["Reactome","R-HSA-1474165","Reproduction",0.3544749870938672,0.9090328958135842,26.0,1.0,137087.15384615384,"57829"]
["Reactome","R-HSA-211897","Cytochrome P450 - arranged by substrate type",0.354867150618386,0.9090328958135842,65.0,4.0,101641.32307692307,"10499, 196, 9915, 66002"]
["Reactome","R-HSA-5673000","RAF activation",0.35559926070139836,0.9090328958135842,25.0,1.0,94751.56,"6714"]
["Reactome","R-HSA-5620912","Anchoring of the basal body to the plasma membrane",0.3573179593512032,0.9090328958135842,98.0,6.0,88115.60204081633,"1639, 4751, 11064, 55722, 95681, 117177"]
["Reactome","R-HSA-70895","Branched-chain amino acid catabolism",0.3576170033181964,0.9090328958135842,23.0,1.0,128410.08695652174,"549"]
["Reactome","R-HSA-427389","ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression",0.3583376267843868,0.9090328958135842,71.0,1.0,25933.140845070422,"8353"]
["Reactome","R-HSA-69206","G1/S Transition",0.359399944245235,0.9090328958135842,118.0,7.0,96154.66949152542,"595, 5689, 5925, 7027, 9861, 10000, 23649"]
["Reactome","R-HSA-69300","Removal of licensing factors from origins",0.36218374643903056,0.9094651320424367,73.0,3.0,63387.27397260274,"5689, 5925, 9861"]
["Reactome","R-HSA-156902","Peptide chain elongation",0.36260820713255343,0.9094651320424367,89.0,3.0,55288.93258426966,"6156, 6228, 6229"]
["Reactome","R-HSA-5357905","Regulation of TNFR1 signaling",0.3643213760291735,0.9100529154240204,33.0,1.0,66751.87878787878,"8737"]
["Reactome","R-HSA-349425","Autodegradation of the E3 ubiquitin ligase COP1",0.36605784089236676,0.9117707972457337,52.0,2.0,69767.86538461539,"5689, 9861"]
["KEGG Pathways","hsa00910","Nitrogen metabolism",0.3662195346627909,0.7695948410902962,23.0,1.0,157958.60869565216,"762"]
["KEGG Pathways","hsa04120","Ubiquitin mediated proteolysis",0.3691600241541134,0.7695948410902962,134.0,11.0,144012.78358208956,"6477, 4214, 5071, 7318, 8452, 8924, 8925, 9021, 22954, 25898, 26259"]
["Reactome","R-HSA-1482839","Acyl chain remodelling of PE",0.36998967962902835,0.9194456176528267,28.0,1.0,133106.75,"50487"]
["KEGG Pathways","hsa00591","Linoleic acid metabolism",0.37282707147526273,0.7695948410902962,28.0,1.0,135594.85714285713,"50487"]
["Reactome","R-HSA-5654706","FRS-mediated FGFR3 signaling",0.37342132051495835,0.9231554734010353,20.0,1.0,133712.0,"2261"]
["KEGG Pathways","hsa04140","Regulation of autophagy",0.3754121176050226,0.7695948410902962,34.0,1.0,67372.20588235294,"3458"]
["Reactome","R-HSA-948021","Transport to the Golgi and subsequent modification",0.37564494778826957,0.9231554734010353,180.0,13.0,113854.45,"6480, 286, 2890, 83696, 287, 1081, 1639, 4121, 10175, 11320, 57134, 64377, 338596"]
["Reactome","R-HSA-5654688","SHC-mediated cascade:FGFR1",0.37589871517512513,0.9231554734010353,21.0,1.0,130986.09523809524,"2260"]
["Reactome","R-HSA-416572","Sema4D induced cell migration and growth-cone collapse",0.37836627340404616,0.9231554734010353,24.0,1.0,163188.66666666666,"4627"]
["Reactome","R-HSA-210993","Tie2 Signaling",0.3798513463465421,0.9231554734010353,18.0,1.0,200908.94444444444,"5295"]
["Reactome","R-HSA-912446","Meiotic recombination",0.3826575203973984,0.9231554734010353,82.0,2.0,45410.08536585366,"8353, 11144"]
["Reactome","R-HSA-70268","Pyruvate metabolism",0.38355032643962195,0.9231554734010353,27.0,1.0,79341.18518518518,"9123"]
["Reactome","R-HSA-446652","Interleukin-1 signaling",0.3837063105898315,0.9231554734010353,45.0,3.0,131087.3111111111,"3553, 6416, 64127"]
["Reactome","R-HSA-180585","Vif-mediated degradation of APOBEC3G",0.38514627058637085,0.9231554734010353,54.0,2.0,62411.18518518518,"5689, 9861"]
["KEGG Pathways","hsa02010","ABC transporters",0.38978155099312006,0.7723969148675671,44.0,3.0,128866.95454545454,"5244, 8647, 23460"]
["Reactome","R-HSA-76046","RNA Polymerase III Transcription Initiation",0.3903622385185388,0.9288695069984777,36.0,1.0,55914.75,"5451"]
["Reactome","R-HSA-420499","Class C/3 (Metabotropic glutamate/pheromone receptors)",0.3909672763037071,0.9288695069984777,39.0,2.0,148886.07692307694,"2914, 50834"]
["Reactome","R-HSA-5689880","Ub-specific processing proteases",0.3929142823191702,0.9299157826000835,212.0,13.0,95435.2075471698,"4088, 8313, 154, 4086, 4089, 5689, 8737, 9736, 9804, 9861, 11047, 90865, 219333"]
["Reactome","R-HSA-1482788","Acyl chain remodelling of PC",0.3954779357965314,0.9299157826000835,27.0,1.0,134105.85185185185,"50487"]
["Reactome","R-HSA-68949","Orc1 removal from chromatin",0.3959256347048318,0.9299157826000835,71.0,3.0,63110.126760563384,"5689, 5925, 9861"]
["Reactome","R-HSA-69052","Switching of origins to a post-replicative state",0.3959256347048318,0.9299157826000835,71.0,3.0,63110.126760563384,"5689, 5925, 9861"]
["Reactome","R-HSA-1268020","Mitochondrial protein import",0.3974293168929126,0.9299157826000835,60.0,2.0,50828.166666666664,"3313, 9804"]
["KEGG Pathways","hsa00240","Pyrimidine metabolism",0.4011257627928221,0.7723969148675671,98.0,5.0,76585.55102040817,"955, 1807, 9583, 23649, 25885"]
["Reactome","R-HSA-179409","APC-Cdc20 mediated degradation of Nek2A",0.40167843677597853,0.9333465201376827,24.0,1.0,104637.20833333333,"4751"]
["Reactome","R-HSA-5663220","RHO GTPases Activate Formins",0.40214209743836393,0.9333465201376827,132.0,10.0,130610.26515151515,"8379, 699, 1063, 1855, 5501, 6714, 23002, 55839, 81565, 378708"]
["Reactome","R-HSA-168638","NOD1/2 Signaling Pathway",0.40320746643777156,0.9333465201376827,36.0,2.0,120285.19444444444,"834, 64127"]
["Reactome","R-HSA-5693537","Resolution of D-Loop Structures",0.4047913196394714,0.9333465201376827,34.0,2.0,123154.44117647059,"5890, 116028"]
["Reactome","R-HSA-180534","Vpu mediated degradation of CD4",0.40493942455557186,0.9333465201376827,52.0,2.0,63806.730769230766,"5689, 9861"]
["KEGG Pathways","hsa00512","Mucin type O-Glycan biosynthesis",0.4050914073416846,0.7723969148675671,30.0,3.0,284159.1,"79623, 2591, 50614"]
["Reactome","R-HSA-5654726","Negative regulation of FGFR1 signaling",0.4082338628602664,0.9389378845786127,33.0,2.0,174072.84848484848,"2260, 6714"]
["Reactome","R-HSA-5693568","Resolution of D-loop Structures through Holliday Junction Intermediates",0.41445625222146704,0.949210187820775,33.0,2.0,126239.87878787878,"5890, 116028"]
["KEGG Pathways","hsa05320","Autoimmune thyroid disease",0.4189554914915164,0.7837970453539456,50.0,2.0,64468.06,"1081, 7173"]
["Reactome","R-HSA-983169","Class I MHC mediated antigen processing & presentation",0.4216753076462872,0.9630980068050711,368.0,30.0,114818.73913043478,"80176, 6477, 29116, 1514, 4688, 5071, 5689, 7099, 7318, 7336, 7704, 8452, 8924, 8925, 9021, 9861, 9902, 10333, 10422, 22954, 25897, 25898, 26259, 55521, 55819, 84541, 84676, 84708, 92369, 144699"]
["Reactome","R-HSA-69618","Mitotic Spindle Checkpoint",0.4263624201572627,0.968316135605765,20.0,1.0,127850.7,"8379"]
["Reactome","R-HSA-2426168","Activation of gene expression by SREBF (SREBP)",0.42827063574010554,0.9693845425180301,42.0,3.0,148480.2857142857,"10499, 1387, 80205"]
["Reactome","R-HSA-5654704","SHC-mediated cascade:FGFR3",0.4311268218881316,0.9703328278496669,18.0,1.0,137317.22222222222,"2261"]
["Reactome","R-HSA-977606","Regulation of Complement cascade",0.43186167670365505,0.9703328278496669,27.0,1.0,146265.62962962964,"718"]
["Reactome","R-HSA-933542","TRAF6 mediated NF-kB activation",0.4326553404473075,0.9703328278496669,25.0,1.0,89898.96,"4214"]
["Reactome","R-HSA-6807505","RNA polymerase II transcribes snRNA genes",0.43724045075954004,0.9726910685202514,71.0,3.0,60594.16901408451,"5451, 8812, 79664"]
["Reactome","R-HSA-174417","Telomere C-strand (Lagging Strand) Synthesis",0.4384710805431489,0.9726910685202514,24.0,1.0,99480.04166666667,"23649"]
["Reactome","R-HSA-69615","G1/S DNA Damage Checkpoints",0.4417930303013298,0.9726910685202514,66.0,3.0,66581.40909090909,"5689, 9861, 11200"]
["Reactome","R-HSA-5627117","RHO GTPases Activate ROCKs",0.44468651321162306,0.9726910685202514,17.0,1.0,228409.41176470587,"4627"]
["KEGG Pathways","hsa03410","Base excision repair",0.44784777409593374,0.8205354969086032,33.0,1.0,55952.030303030304,"143"]
["Reactome","R-HSA-112314","Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell",0.44980304418778805,0.9726910685202514,144.0,16.0,208177.77083333334,"2890, 107, 2562, 2793, 2898, 2900, 2901, 2903, 2905, 3768, 3773, 5330, 5567, 6196, 84254, 196883"]
["Reactome","R-HSA-1236974","ER-Phagosome pathway",0.45025420309195674,0.9726910685202514,83.0,4.0,73399.63855421687,"5689, 7099, 9861, 10333"]
["Reactome","R-HSA-5223345","Miscellaneous transport and binding events",0.4517577009936471,0.9726910685202514,21.0,1.0,107096.47619047618,"2039"]
["KEGG Pathways","hsa04114","Oocyte meiosis",0.45245094788930074,0.8208180913035986,110.0,9.0,145933.43636363637,"810, 3708, 107, 699, 3709, 5501, 5567, 6196, 196883"]
["Reactome","R-HSA-211733","Regulation of activated PAK-2p34 by proteasome mediated degradation",0.45250607743760785,0.9726910685202514,50.0,2.0,62814.58,"5689, 9861"]
["Reactome","R-HSA-4791275","Signaling by WNT in cancer",0.4532159253382905,0.9726910685202514,34.0,3.0,184078.82352941178,"6934, 1499, 324"]
["Reactome","R-HSA-5620922","BBSome-mediated cargo-targeting to cilium",0.4537224424872652,0.9726910685202514,23.0,1.0,96469.34782608696,"117177"]
["Reactome","R-HSA-73847","Purine metabolism",0.454752343170108,0.9726910685202514,34.0,2.0,103992.20588235294,"64077, 272"]
["Reactome","R-HSA-69017","CDK-mediated phosphorylation and removal of Cdc6",0.4570787918121867,0.9726910685202514,51.0,2.0,61008.35294117647,"5689, 9861"]
["Reactome","R-HSA-1483257","Phospholipid metabolism",0.4584060870704265,0.9726910685202514,202.0,17.0,127069.599009901,"5287, 9663, 55500, 590, 1757, 5293, 5295, 5867, 9108, 11343, 22874, 23761, 25816, 50487, 54477, 55326, 388121"]
["Reactome","R-HSA-197264","Nicotinamide salvaging",0.46169948129564686,0.9726910685202514,18.0,1.0,156006.38888888888,"143"]
["Reactome","R-HSA-1538133","G0 and Early G1",0.4625583381826778,0.9726910685202514,25.0,1.0,78836.96,"7027"]
["Reactome","R-HSA-199991","Membrane Trafficking",0.46307075727555713,0.9726910685202514,622.0,56.0,120560.05466237942,"125058, 286, 338, 274, 2890, 7163, 51422, 54453, 83696, 154, 185, 273, 287, 547, 1212, 1639, 1956, 2060, 2697, 2700, 2702, 2703, 2810, 4121, 4625, 5866, 5867, 6714, 6764, 7474, 9525, 9685, 10000, 10175, 11037, 22989, 23216, 25782, 26119, 26153, 27147, 29993, 51112, 51762, 54536, 55330, 57134, 57186, 57533, 60592, 79890, 81846, 85439, 112574, 117177, 221458"]
["Reactome","R-HSA-5654700","FRS-mediated FGFR2 signaling",0.4643763221245132,0.9726910685202514,25.0,2.0,171833.52,"2252, 2263"]
["Reactome","R-HSA-4615885","SUMOylation of DNA replication proteins",0.4654921025246002,0.9726910685202514,44.0,2.0,76021.93181818182,"8021, 23225"]
["Reactome","R-HSA-5610780","Degradation of GLI1 by the proteasome",0.4706452400932154,0.9726910685202514,60.0,3.0,72507.0,"5567, 5689, 9861"]
["KEGG Pathways","hsa04622","RIG-I-like receptor signaling pathway",0.47144615090448083,0.8404040081340745,71.0,4.0,89279.85915492958,"3592, 4214, 7187, 8737"]
["Reactome","R-HSA-69563","p53-Dependent G1 DNA Damage Response",0.47258440534629415,0.9726910685202514,64.0,3.0,67231.625,"5689, 9861, 11200"]
["Reactome","R-HSA-69580","p53-Dependent G1/S DNA damage checkpoint",0.47258440534629415,0.9726910685202514,64.0,3.0,67231.625,"5689, 9861, 11200"]
["Reactome","R-HSA-4085001","Sialic acid metabolism",0.4740005971703249,0.9726910685202514,33.0,3.0,194739.45454545456,"6480, 8869, 338596"]
["Reactome","R-HSA-5620924","Intraflagellar transport",0.4750210186518937,0.9726910685202514,54.0,3.0,81747.46296296296,"83657, 64792, 200132"]
["Reactome","R-HSA-6803204","TP53 Regulates Transcription of Genes Involved in Cytochrome C Release",0.47509504759015736,0.9726910685202514,21.0,1.0,103038.90476190476,"1387"]
["Reactome","R-HSA-190242","FGFR1 ligand binding and activation",0.47741674496973624,0.9726910685202514,16.0,1.0,151875.0625,"2260"]
["Reactome","R-HSA-5655302","Signaling by FGFR1 in disease",0.47954967145442584,0.9726910685202514,38.0,3.0,142464.68421052632,"2260, 5295, 11064"]
["Reactome","R-HSA-5339562","Uptake and actions of bacterial toxins",0.47992823150279684,0.9726910685202514,30.0,2.0,152822.46666666667,"10015, 6416"]
["Reactome","R-HSA-140877","Formation of Fibrin Clot (Clotting Cascade)",0.4805076203516823,0.9726910685202514,38.0,2.0,134702.1052631579,"2152, 2155"]
["KEGG Pathways","hsa05145","Toxoplasmosis",0.48110663403817255,0.845746207914892,129.0,10.0,132499.34108527133,"3655, 3458, 3592, 3910, 3918, 5293, 5295, 7099, 10000, 50487"]
["KEGG Pathways","hsa00230","Purine metabolism",0.48269417720020663,0.845746207914892,161.0,13.0,137619.4099378882,"5152, 5144, 954, 107, 272, 955, 5142, 5150, 9583, 10846, 23649, 25885, 196883"]
["Reactome","R-HSA-1500620","Meiosis",0.48285151534484777,0.9726910685202514,115.0,5.0,70352.17391304347,"8353, 11144, 23224, 23345, 50511"]
["Reactome","R-HSA-1912420","Pre-NOTCH Processing in Golgi",0.4832684407444066,0.9726910685202514,18.0,1.0,204256.05555555556,"3955"]
["Reactome","R-HSA-5250924","B-WICH complex positively regulates rRNA expression",0.4844848732452004,0.9726910685202514,88.0,2.0,29243.147727272728,"8353, 25885"]
["Reactome","R-HSA-380320","Recruitment of NuMA to mitotic centrosomes",0.4864728717705958,0.9726910685202514,28.0,1.0,65905.32142857143,"4926"]
["Reactome","R-HSA-5689901","Metalloprotease DUBs",0.4887782487240286,0.9726910685202514,35.0,1.0,48892.42857142857,"9577"]
["Reactome","R-HSA-5654219","Phospholipase C-mediated cascade: FGFR1",0.49444810076124013,0.9726910685202514,16.0,1.0,147777.75,"2260"]
["KEGG Pathways","hsa00590","Arachidonic acid metabolism",0.49479148143072016,0.8523718797756104,58.0,3.0,95414.13793103448,"2678, 2878, 50487"]
["Reactome","R-HSA-2514856","The phototransduction cascade",0.49488804999483876,0.9726910685202514,34.0,2.0,93930.70588235294,"2779, 5957"]
["Reactome","R-HSA-110313","Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template",0.49670846879653535,0.9726910685202514,41.0,2.0,77717.46341463414,"7318, 25898"]
["Reactome","R-HSA-5655253","Signaling by FGFR2 in disease",0.5043055921922799,0.9726910685202514,43.0,3.0,138288.44186046513,"2252, 2263, 5295"]
["Reactome","R-HSA-5654732","Negative regulation of FGFR3 signaling",0.5073696555445704,0.9726910685202514,29.0,2.0,182668.6551724138,"2261, 6714"]
["Reactome","R-HSA-392170","ADP signalling through P2Y purinoceptor 12",0.5090166212573153,0.9726910685202514,23.0,1.0,78148.34782608696,"2793"]
["Reactome","R-HSA-1483249","Inositol phosphate metabolism",0.51129611229689,0.9726910685202514,46.0,4.0,162439.80434782608,"3632, 3706, 5330, 9651"]
["Reactome","R-HSA-193807","Synthesis of bile acids and bile salts via 27-hydroxycholesterol",0.5118298603639346,0.9726910685202514,15.0,1.0,140638.4,"10499"]
["Reactome","R-HSA-68875","Mitotic Prophase",0.514883053980619,0.9726910685202514,135.0,7.0,79970.88148148148,"9663, 5925, 8021, 8353, 23225, 79648, 221496"]
["Reactome","R-HSA-1221632","Meiotic synapsis",0.5159752553617325,0.9726910685202514,75.0,3.0,68635.96,"23224, 23345, 50511"]
["Reactome","R-HSA-1839126","FGFR2 mutant receptor activation",0.5172092380991378,0.9726910685202514,33.0,2.0,120859.24242424243,"2252, 2263"]
["Reactome","R-HSA-2514859","Inactivation, recovery and regulation of the phototransduction cascade",0.5196784134396002,0.9726910685202514,33.0,2.0,94662.24242424243,"2779, 5957"]
["Reactome","R-HSA-432142","Platelet sensitization by LDL",0.5240039469429327,0.9726910685202514,16.0,1.0,275478.875,"338"]
["Reactome","R-HSA-195258","RHO GTPase Effectors",0.5261822371450171,0.9726910685202514,303.0,23.0,113227.82508250825,"8379, 1499, 10458, 10499, 699, 999, 1063, 1855, 2810, 4627, 4638, 4688, 4690, 5501, 6242, 6714, 7456, 8353, 23002, 26999, 55839, 81565, 378708"]
["Reactome","R-HSA-5607761","Dectin-1 mediated noncanonical NF-kB signaling",0.5292016379785864,0.9726910685202514,60.0,3.0,68994.63333333333,"5689, 9020, 9861"]
["Reactome","R-HSA-5654699","SHC-mediated cascade:FGFR2",0.5306077092626229,0.9726910685202514,23.0,2.0,177969.91304347827,"2252, 2263"]
["Reactome","R-HSA-168253","Host Interactions with Influenza Factors",0.5327660458455619,0.9726910685202514,41.0,2.0,76442.87804878049,"8021, 23225"]
["Reactome","R-HSA-5694530","Cargo concentration in the ER",0.533988422990761,0.9726910685202514,34.0,2.0,104011.32352941176,"2890, 10175"]
["Reactome","R-HSA-73863","RNA Polymerase I Transcription Termination",0.5355294876862134,0.9726910685202514,32.0,1.0,53225.0625,"25885"]
["Reactome","R-HSA-450531","Regulation of mRNA stability by proteins that bind AU-rich elements",0.5357017758267404,0.9726910685202514,87.0,5.0,77020.85057471265,"677, 5580, 5689, 8021, 9861"]
["Reactome","R-HSA-69186","Lagging Strand Synthesis",0.5363166445049394,0.9726910685202514,20.0,1.0,107167.95,"23649"]
["Reactome","R-HSA-5693571","Nonhomologous End-Joining (NHEJ)",0.5371093443785245,0.9726910685202514,67.0,3.0,61405.253731343284,"7336, 8924, 9577"]
["Reactome","R-HSA-5678895","Defective CFTR causes cystic fibrosis",0.5399484987526555,0.9726910685202514,61.0,3.0,93511.01639344262,"79139, 5689, 9861"]
["KEGG Pathways","hsa04662","B cell receptor signaling pathway",0.5402464919508457,0.8984967747998696,75.0,6.0,122131.16,"4772, 5293, 5295, 7410, 10000, 10451"]
["Reactome","R-HSA-975956","Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)",0.5408659574829116,0.9726910685202514,95.0,4.0,55515.97894736842,"5976, 6156, 6228, 6229"]
["Reactome","R-HSA-499943","Synthesis and interconversion of nucleotide di- and triphosphates",0.541740313715274,0.9726910685202514,24.0,1.0,67245.33333333333,"2745"]
["KEGG Pathways","hsa05322","Systemic lupus erythematosus",0.543489044816218,0.8984967747998696,126.0,5.0,48259.96031746032,"9555, 718, 2903, 3458, 8353"]
["Reactome","R-HSA-5676590","NIK-->noncanonical NF-kB signaling",0.5442143757878384,0.9726910685202514,59.0,3.0,69604.77966101695,"5689, 9020, 9861"]
["Reactome","R-HSA-73777","RNA Polymerase I Chain Elongation",0.5465005587372462,0.9726910685202514,86.0,2.0,28876.45348837209,"8353, 25885"]
["Reactome","R-HSA-73772","RNA Polymerase I Promoter Escape",0.5479822092148952,0.9726910685202514,31.0,1.0,54637.48387096774,"25885"]
["Reactome","R-HSA-977443","GABA receptor activation",0.5531031220504375,0.9726910685202514,56.0,6.0,204268.5357142857,"107, 2562, 2793, 3768, 3773, 196883"]
["Reactome","R-HSA-5654708","Downstream signaling of activated FGFR3",0.5534729578055839,0.9726910685202514,25.0,2.0,161992.28,"2261, 5295"]
["Reactome","R-HSA-210500","Glutamate Neurotransmitter Release Cycle",0.5536064492017019,0.9726910685202514,24.0,2.0,190377.79166666666,"10815, 8499"]
["Reactome","R-HSA-2142845","Hyaluronan metabolism",0.5540513741987143,0.9726910685202514,16.0,1.0,138198.75,"3038"]
["Reactome","R-HSA-5693554","Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)",0.5556992764176073,0.9726910685202514,27.0,2.0,124846.5925925926,"5890, 116028"]
["Reactome","R-HSA-5619115","Disorders of transmembrane transporters",0.5584984775158888,0.9726910685202514,75.0,4.0,89492.89333333333,"79139, 5689, 9861, 653509"]
["Reactome","R-HSA-202131","Metabolism of nitric oxide",0.5594227430359744,0.9726910685202514,21.0,1.0,80141.09523809524,"115677"]
["Reactome","R-HSA-203765","eNOS activation and regulation",0.5594227430359744,0.9726910685202514,21.0,1.0,80141.09523809524,"115677"]
["Reactome","R-HSA-4641257","Degradation of AXIN",0.5598691630449129,0.9726910685202514,55.0,3.0,76724.70909090909,"8313, 5689, 9861"]
["KEGG Pathways","hsa00534","Glycosaminoglycan biosynthesis - heparan sulfate / heparin",0.5603644528820608,0.9053489984366834,26.0,3.0,357643.1923076923,"9394, 9957, 64131"]
["Reactome","R-HSA-3214841","PKMTs methylate histone lysines",0.561381910201673,0.9726910685202514,70.0,4.0,96912.94285714286,"8353, 11091, 63976, 64754"]
["Reactome","R-HSA-168276"," NS1 Mediated Effects on Host Pathways",0.5624251603524819,0.9726910685202514,39.0,2.0,78556.89743589744,"8021, 23225"]
["Reactome","R-HSA-159234","Transport of Mature mRNAs Derived from Intronless Transcripts",0.5639844079220413,0.9726910685202514,42.0,2.0,72932.04761904762,"8021, 23225"]
["Reactome","R-HSA-354192","Integrin alphaIIb beta3 signaling",0.5724168130822183,0.9726910685202514,27.0,2.0,120760.11111111111,"11069, 6714"]
["Reactome","R-HSA-159231","Transport of Mature mRNA Derived from an Intronless Transcript",0.575287546918182,0.9726910685202514,41.0,2.0,74291.31707317074,"8021, 23225"]
["KEGG Pathways","hsa00531","Glycosaminoglycan degradation",0.5754647706833869,0.9216427967976117,18.0,1.0,123291.72222222222,"411"]
["Reactome","R-HSA-427359","SIRT1 negatively regulates rRNA Expression",0.578261018777992,0.9726910685202514,64.0,1.0,18487.640625,"8353"]
["Reactome","R-HSA-435354","Zinc transporters",0.5793352939138509,0.9726910685202514,17.0,1.0,187181.4705882353,"57181"]
["Reactome","R-HSA-2559580","Oxidative Stress Induced Senescence",0.5793757392709724,0.9726910685202514,120.0,6.0,61869.1,"6416, 7027, 8353, 27327, 57332, 57690"]
["Reactome","R-HSA-4608870","Asymmetric localization of PCP proteins",0.5795168584175535,0.9726910685202514,65.0,4.0,95224.10769230769,"8321, 5689, 7474, 9861"]
["Reactome","R-HSA-3371453","Regulation of HSF1-mediated heat shock response",0.5795982740813586,0.9726910685202514,68.0,4.0,77339.51470588235,"3313, 8021, 23225, 116835"]
["KEGG Pathways","hsa00514","Other types of O-glycan biosynthesis",0.5817302353218589,0.9226635913380563,46.0,3.0,103487.15217391304,"6480, 3955, 727936"]
["Reactome","R-HSA-354194","GRB2:SOS provides linkage to MAPK signaling for Integrins ",0.5817771690917315,0.9726910685202514,15.0,1.0,124619.26666666666,"6714"]
["Reactome","R-HSA-5654727","Negative regulation of FGFR2 signaling",0.5818225265954539,0.9726910685202514,34.0,3.0,203499.67647058822,"2252, 2263, 6714"]
["Reactome","R-HSA-3301854","Nuclear Pore Complex (NPC) Disassembly",0.5848372506054699,0.9726910685202514,34.0,2.0,93051.88235294117,"8021, 23225"]
["Reactome","R-HSA-2559583","Cellular Senescence",0.585788954689384,0.9726910685202514,189.0,12.0,93224.1746031746,"2114, 3005, 3490, 5925, 6196, 6416, 7027, 8091, 8353, 27327, 57332, 57690"]
["KEGG Pathways","hsa00520","Amino sugar and nucleotide sugar metabolism",0.5859592495862127,0.9226635913380563,47.0,3.0,97195.14893617021,"9945, 29926, 2762"]
["Reactome","R-HSA-5688426","Deubiquitination",0.5865284072722258,0.9726910685202514,289.0,21.0,102133.26989619377,"4088, 8313, 154, 324, 2099, 4086, 4089, 5071, 5689, 7187, 8737, 9577, 9736, 9804, 9861, 11047, 23252, 64127, 90865, 219333, 221937"]
["Reactome","R-HSA-76071","RNA Polymerase III Transcription Initiation From Type 3 Promoter",0.5869801902792828,0.9726910685202514,28.0,1.0,54246.92857142857,"5451"]
["Reactome","R-HSA-71403","Citric acid cycle (TCA cycle)",0.5871710139151386,0.9726910685202514,19.0,1.0,103279.78947368421,"6390"]
["Reactome","R-HSA-6804760","Regulation of TP53 Activity through Methylation",0.5904610638761758,0.9726910685202514,20.0,1.0,78688.8,"11200"]
["Reactome","R-HSA-936440","Negative regulators of RIG-I/MDA5 signaling",0.5907789771715863,0.9726910685202514,36.0,2.0,75428.77777777778,"7187, 7318"]
["Reactome","R-HSA-380270","Recruitment of mitotic centrosome proteins and complexes",0.593169030365605,0.9726910685202514,93.0,6.0,76494.95698924731,"1639, 4751, 4926, 11064, 55722, 95681"]
["Reactome","R-HSA-380287","Centrosome maturation",0.593169030365605,0.9726910685202514,93.0,6.0,76494.95698924731,"1639, 4751, 4926, 11064, 55722, 95681"]
["Reactome","R-HSA-2022377","Metabolism of Angiotensinogen to Angiotensins",0.5956749421407234,0.9726910685202514,17.0,1.0,116912.94117647059,"5972"]
["Reactome","R-HSA-5387390","Hh mutants abrogate ligand secretion",0.5959193581542943,0.9726910685202514,58.0,3.0,96855.6551724138,"5689, 9861, 50846"]
["Reactome","R-HSA-351202","Metabolism of polyamines",0.5959707629148826,0.9726910685202514,86.0,5.0,69207.82558139534,"51582, 445, 5689, 6539, 9861"]
["Reactome","R-HSA-8875360","InlB-mediated entry of Listeria monocytogenes into host cell",0.5966494460519329,0.9726910685202514,15.0,1.0,142410.8,"2060"]
["Reactome","R-HSA-193639","p75NTR signals via NF-kB",0.5982856430122783,0.9726910685202514,17.0,1.0,123256.05882352941,"4804"]
["Reactome","R-HSA-1660662","Glycosphingolipid metabolism",0.601580603242416,0.9726910685202514,44.0,3.0,123917.38636363637,"411, 22901, 340075"]
["Reactome","R-HSA-2142691","Synthesis of Leukotrienes (LT) and Eoxins (EX)",0.6025315746823716,0.9726910685202514,22.0,1.0,64574.86363636364,"2678"]
["Reactome","R-HSA-917729","Endosomal Sorting Complex Required For Transport (ESCRT)",0.6042474767361041,0.9726910685202514,28.0,1.0,47072.75,"9525"]
["Reactome","R-HSA-5655332","Signaling by FGFR3 in disease",0.6042862647941374,0.9726910685202514,22.0,2.0,179138.0,"2261, 5295"]
["Reactome","R-HSA-8853338","Signaling by FGFR3 point mutants in cancer",0.6042862647941374,0.9726910685202514,22.0,2.0,179138.0,"2261, 5295"]
["Reactome","R-HSA-168643","Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",0.6069364997088742,0.9726910685202514,52.0,4.0,119780.25,"834, 9051, 10628, 64127"]
["Reactome","R-HSA-73728","RNA Polymerase I Promoter Opening",0.6071052093847407,0.9726910685202514,58.0,1.0,26441.327586206895,"8353"]
["KEGG Pathways","hsa05330","Allograft rejection",0.6085054148544293,0.9379218800387821,35.0,2.0,80025.22857142857,"3458, 3592"]
["Reactome","R-HSA-202403","TCR signaling",0.6102313517596547,0.9726910685202514,116.0,9.0,105245.9051724138,"919, 2533, 3702, 3937, 4690, 5295, 5689, 9861, 55824"]
["Reactome","R-HSA-212676","Dopamine Neurotransmitter Release Cycle",0.6116892320802901,0.9726910685202514,22.0,2.0,222015.72727272726,"10815, 8499"]
["Reactome","R-HSA-372708","p130Cas linkage to MAPK signaling for integrins",0.6124692899675795,0.9726910685202514,15.0,1.0,118463.4,"6714"]
["Reactome","R-HSA-5684264","MAP3K8 (TPL2)-dependent MAPK1/3 activation",0.6142806936523204,0.9726910685202514,16.0,1.0,106206.875,"6416"]
["Reactome","R-HSA-390522","Striated Muscle Contraction",0.615162133161059,0.9726910685202514,36.0,2.0,138257.63888888888,"7140, 7111"]
["Reactome","R-HSA-3928662","EPHB-mediated forward signaling",0.61859212732527,0.9726910685202514,41.0,4.0,206414.48780487804,"2049, 2534, 6714, 8997"]
["Reactome","R-HSA-1483191","Synthesis of PC",0.6197469968807212,0.9726910685202514,28.0,2.0,129732.71428571429,"9663, 590"]
["Reactome","R-HSA-167287","HIV elongation arrest and recovery",0.6201476404471296,0.9726910685202514,37.0,1.0,33325.48648648649,"8812"]
["Reactome","R-HSA-167290","Pausing and recovery of HIV elongation",0.6201476404471296,0.9726910685202514,37.0,1.0,33325.48648648649,"8812"]
["Reactome","R-HSA-190241","FGFR2 ligand binding and activation",0.620733078708023,0.9726910685202514,20.0,2.0,191426.45,"2252, 2263"]
["Reactome","R-HSA-211945","Phase 1 - Functionalization of compounds",0.6244537328450885,0.9726910685202514,106.0,8.0,92525.7075471698,"10499, 125, 196, 216, 2326, 9915, 66002, 84532"]
["Reactome","R-HSA-187577","SCF(Skp2)-mediated degradation of p27/p21",0.6278653526271927,0.9726910685202514,60.0,3.0,61602.46666666667,"595, 5689, 9861"]
["Reactome","R-HSA-5334118","DNA methylation",0.628500806268644,0.9726910685202514,60.0,1.0,18377.566666666666,"8353"]
["Reactome","R-HSA-69541","Stabilization of p53",0.6289071004410359,0.9726910685202514,55.0,3.0,70116.4909090909,"5689, 9861, 11200"]
["Reactome","R-HSA-5654696","Downstream signaling of activated FGFR2",0.6295867556812957,0.9726910685202514,30.0,3.0,189046.83333333334,"2252, 2263, 5295"]
["Reactome","R-HSA-169911","Regulation of Apoptosis",0.633737737715955,0.9726910685202514,53.0,3.0,74686.98113207547,"4976, 5689, 9861"]
["KEGG Pathways","hsa00650","Butanoate metabolism",0.6346347842752293,0.9492096985048285,30.0,2.0,124548.63333333333,"622, 2572"]
["Reactome","R-HSA-212300","PRC2 methylates histones and DNA",0.6348204653950976,0.9726910685202514,68.0,2.0,44940.220588235294,"3720, 8353"]
["Reactome","R-HSA-176033","Interactions of Vpr with host cellular proteins",0.6372778165118205,0.9726910685202514,35.0,2.0,82988.4857142857,"8021, 23225"]
["Reactome","R-HSA-69656","Cyclin A:Cdk2-associated events at S phase entry",0.6396585889320452,0.9726910685202514,70.0,4.0,70659.61428571428,"595, 5689, 5925, 9861"]
["KEGG Pathways","hsa03010","Ribosome",0.6414785262471416,0.9492096985048285,88.0,4.0,56009.09090909091,"6156, 6228, 6229, 51187"]
["Reactome","R-HSA-110320","Translesion Synthesis by POLH",0.6418657804015835,0.9726910685202514,19.0,1.0,86572.73684210527,"25898"]
["Reactome","R-HSA-2559586","DNA Damage/Telomere Stress Induced Senescence",0.645835253169705,0.9726910685202514,75.0,3.0,58021.88,"3005, 5925, 8091"]
["KEGG Pathways","hsa05332","Graft-versus-host disease",0.6475819654027684,0.9492096985048285,37.0,2.0,68624.62162162163,"3458, 3553"]
["Reactome","R-HSA-70221","Glycogen breakdown (glycogenolysis)",0.6518043734768573,0.9726910685202514,16.0,1.0,103642.25,"5257"]
["KEGG Pathways","hsa05310","Asthma",0.6540834144203562,0.9492096985048285,28.0,1.0,41599.92857142857,"6356"]
["Reactome","R-HSA-8854518","AURKA Activation by TPX2",0.6591937784149854,0.9726910685202514,73.0,5.0,82512.87671232877,"1639, 4751, 11064, 55722, 95681"]
["KEGG Pathways","hsa00562","Inositol phosphate metabolism",0.6596752795232093,0.9492096985048285,57.0,5.0,146471.98245614034,"5287, 3632, 3706, 5293, 5330"]
["KEGG Pathways","hsa04975","Fat digestion and absorption",0.6596781019875119,0.9492096985048285,45.0,3.0,155476.73333333334,"338, 337, 50487"]
["KEGG Pathways","hsa00532","Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",0.6621316433472706,0.9492096985048285,22.0,2.0,194956.0909090909,"10090, 64131"]
["Reactome","R-HSA-168325","Viral Messenger RNA Synthesis",0.6633919411032027,0.9726910685202514,42.0,2.0,65997.71428571429,"8021, 23225"]
["Reactome","R-HSA-450294","MAP kinase activation in TLR cascade",0.6634578176855386,0.9726910685202514,64.0,6.0,148191.6875,"1846, 4205, 1848, 6196, 6416, 64127"]
["Reactome","R-HSA-2980766","Nuclear Envelope Breakdown",0.6684140591536079,0.9726910685202514,51.0,4.0,127750.88235294117,"9663, 8021, 23225, 221496"]
["Reactome","R-HSA-177243","Interactions of Rev with host cellular proteins",0.6694923917974663,0.9726910685202514,35.0,2.0,80914.4857142857,"8021, 23225"]
["Reactome","R-HSA-5625740","RHO GTPases activate PKNs",0.671751695051702,0.9726910685202514,88.0,4.0,69027.95454545454,"10499, 2810, 4627, 8353"]
["Reactome","R-HSA-3928663","EPHA-mediated growth cone collapse",0.6768319731940722,0.9726910685202514,34.0,4.0,433008.20588235295,"1946, 2534, 4627, 6714"]
["Reactome","R-HSA-5625900","RHO GTPases activate CIT",0.6778404213922153,0.9726910685202514,17.0,1.0,83406.94117647059,"4627"]
["KEGG Pathways","hsa04540","Gap junction",0.6784174408986882,0.9653001452691597,89.0,10.0,203247.59550561797,"3708, 107, 1956, 2697, 2778, 3709, 5330, 5567, 6714, 196883"]
["Reactome","R-HSA-442742","CREB phosphorylation through the activation of Ras",0.6819090141256778,0.9726910685202514,28.0,3.0,183128.2857142857,"2903, 2905, 6196"]
["Reactome","R-HSA-5654221","Phospholipase C-mediated cascade; FGFR2",0.682352862653149,0.9726910685202514,18.0,2.0,205946.88888888888,"2252, 2263"]
["Reactome","R-HSA-5654687","Downstream signaling of activated FGFR1",0.6831524671468643,0.9726910685202514,31.0,3.0,192767.48387096773,"23769, 2260, 5295"]
["Reactome","R-HSA-5654736","Signaling by FGFR1",0.6872870315158008,0.9726910685202514,50.0,5.0,208550.0,"23769, 2260, 5295, 6714, 53834"]
["Reactome","R-HSA-69205","G1/S-Specific Transcription",0.6880996046086076,0.9726910685202514,18.0,1.0,76730.55555555556,"7027"]
["Reactome","R-HSA-5654689","PI-3K cascade:FGFR1",0.6920492989191287,0.9726910685202514,21.0,2.0,179964.47619047618,"2260, 5295"]
["Reactome","R-HSA-389977","Post-chaperonin tubulin folding pathway",0.6925687723366132,0.9726910685202514,22.0,1.0,58898.5,"6904"]
["Reactome","R-HSA-6804758","Regulation of TP53 Activity through Acetylation",0.6931015285346124,0.9726910685202514,31.0,2.0,85332.09677419355,"10000, 29117"]
["Reactome","R-HSA-380259","Loss of Nlp from mitotic centrosomes",0.699161040655092,0.9726910685202514,70.0,5.0,84814.24285714286,"1639, 4751, 11064, 55722, 95681"]
["Reactome","R-HSA-380284","Loss of proteins required for interphase microtubule organization from the centrosome",0.699161040655092,0.9726910685202514,70.0,5.0,84814.24285714286,"1639, 4751, 11064, 55722, 95681"]
["Reactome","R-HSA-168142","Toll Like Receptor 10 (TLR10) Cascade",0.6999872676413292,0.9726910685202514,84.0,8.0,141850.9880952381,"1846, 4205, 1848, 4214, 6196, 6416, 7100, 64127"]
["Reactome","R-HSA-168176","Toll Like Receptor 5 (TLR5) Cascade",0.6999872676413292,0.9726910685202514,84.0,8.0,141850.9880952381,"1846, 4205, 1848, 4214, 6196, 6416, 7100, 64127"]
["Reactome","R-HSA-975871","MyD88 cascade initiated on plasma membrane",0.6999872676413292,0.9726910685202514,84.0,8.0,141850.9880952381,"1846, 4205, 1848, 4214, 6196, 6416, 7100, 64127"]
["Reactome","R-HSA-202040","G-protein activation",0.701607905723285,0.9726910685202514,29.0,2.0,96942.62068965517,"2779, 2793"]
["Reactome","R-HSA-1482925","Acyl chain remodelling of PG",0.7048122990809048,0.9726910685202514,18.0,1.0,158806.27777777778,"50487"]
["Reactome","R-HSA-418592","ADP signalling through P2Y purinoceptor 1",0.7050722491740528,0.9726910685202514,25.0,2.0,175803.48,"2793, 6714"]
["Reactome","R-HSA-912694","Regulation of IFNA signaling",0.7058739928036019,0.9726910685202514,26.0,1.0,43956.57692307692,"9021"]
["Reactome","R-HSA-1632852","Macroautophagy",0.7063181629610823,0.9726910685202514,66.0,5.0,94645.04545454546,"51422, 57521, 60673, 26100, 64121"]
["Reactome","R-HSA-381070","IRE1alpha activates chaperones",0.7065171643926049,0.9726910685202514,55.0,3.0,59299.181818181816,"1639, 10106, 10130"]
["Reactome","R-HSA-437239","Recycling pathway of L1",0.7076473282344438,0.9726910685202514,47.0,4.0,122830.65957446808,"1808, 6196, 6714, 57698"]
["Reactome","R-HSA-165054","Rev-mediated nuclear export of HIV RNA",0.710544482115191,0.9726910685202514,33.0,2.0,83823.09090909091,"8021, 23225"]
["KEGG Pathways","hsa04666","Fc gamma R-mediated phagocytosis",0.7107509526549275,0.9844861168531089,94.0,9.0,157415.86170212767,"273, 4082, 5293, 5295, 5580, 7410, 8877, 10000, 10451"]
["Reactome","R-HSA-5610785","GLI3 is processed to GLI3R by the proteasome",0.7107936682885341,0.9726910685202514,60.0,4.0,85211.26666666666,"2737, 5567, 5689, 9861"]
["Reactome","R-HSA-192105","Synthesis of bile acids and bile salts",0.7137549603307126,0.9726910685202514,34.0,3.0,115355.05882352941,"10499, 8647, 26031"]
["Reactome","R-HSA-5627123","RHO GTPases activate PAKs",0.7144081375095319,0.9726910685202514,22.0,2.0,127827.09090909091,"4627, 4638"]
["Reactome","R-HSA-1295596","Spry regulation of FGF signaling",0.7152917411933317,0.9726910685202514,16.0,1.0,200119.875,"6714"]
["Reactome","R-HSA-5610783","Degradation of GLI2 by the proteasome",0.7195866314716985,0.9726910685202514,60.0,4.0,81340.45,"2736, 5567, 5689, 9861"]
["Reactome","R-HSA-504046","RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription",0.7215695828660607,0.9726910685202514,144.0,7.0,58173.131944444445,"4784, 4774, 4781, 4782, 5451, 8353, 25885"]
["Reactome","R-HSA-2033519","Activated point mutants of FGFR2",0.7290081589694537,0.9726910685202514,17.0,2.0,212034.4705882353,"2252, 2263"]
["Reactome","R-HSA-5626467","RHO GTPases activate IQGAPs",0.7291670934854861,0.9726910685202514,31.0,2.0,81953.93548387097,"1499, 999"]
["Reactome","R-HSA-193368","Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol",0.7301946084935025,0.9726910685202514,24.0,2.0,113203.08333333333,"10499, 8647"]
["Reactome","R-HSA-156590","Glutathione conjugation",0.7307977175123965,0.9726910685202514,36.0,2.0,59965.555555555555,"2678, 4258"]
["KEGG Pathways","hsa05220","Chronic myeloid leukemia",0.7328089597766949,0.9972036749469189,73.0,7.0,155967.12328767125,"4088, 595, 4089, 5293, 5295, 5925, 10000"]
["Reactome","R-HSA-927802","Nonsense-Mediated Decay (NMD)",0.7328319156280856,0.9726910685202514,115.0,6.0,57593.11304347826,"23293, 5976, 6156, 6228, 6229, 56006"]
["Reactome","R-HSA-975957","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)",0.7328319156280856,0.9726910685202514,115.0,6.0,57593.11304347826,"23293, 5976, 6156, 6228, 6229, 56006"]
["Reactome","R-HSA-1369062","ABC transporters in lipid homeostasis",0.733460543893794,0.9726910685202514,17.0,1.0,76938.17647058824,"23460"]
["Reactome","R-HSA-1839124","FGFR1 mutant receptor activation",0.7341181385954434,0.9726910685202514,31.0,3.0,148091.4193548387,"2260, 5295, 11064"]
["KEGG Pathways","hsa00770","Pantothenate and CoA biosynthesis",0.734525633741389,0.9972036749469189,16.0,1.0,105268.3125,"1807"]
["Reactome","R-HSA-194068","Bile acid and bile salt metabolism",0.7390007518715129,0.9726910685202514,43.0,4.0,115722.16279069768,"10499, 6579, 8647, 26031"]
["Reactome","R-HSA-5620916","VxPx cargo-targeting to cilium",0.7402693362130407,0.9726910685202514,21.0,2.0,159966.38095238095,"54536, 117177"]
["Reactome","R-HSA-73848","Pyrimidine metabolism",0.7436813091265826,0.9726910685202514,26.0,2.0,111764.03846153847,"1807, 100500832"]
["Reactome","R-HSA-166058","MyD88:Mal cascade initiated on plasma membrane",0.7449672243297247,0.9726910685202514,94.0,9.0,143369.4255319149,"1846, 4205, 1848, 4214, 6196, 6416, 7099, 10333, 64127"]
["Reactome","R-HSA-168188","Toll Like Receptor TLR6:TLR2 Cascade",0.7449672243297247,0.9726910685202514,94.0,9.0,143369.4255319149,"1846, 4205, 1848, 4214, 6196, 6416, 7099, 10333, 64127"]
["Reactome","R-HSA-606279","Deposition of new CENPA-containing nucleosomes at the centromere",0.7456642280917236,0.9726910685202514,68.0,3.0,59715.80882352941,"55355, 55839, 378708"]
["Reactome","R-HSA-774815","Nucleosome assembly",0.7456642280917236,0.9726910685202514,68.0,3.0,59715.80882352941,"55355, 55839, 378708"]
["Reactome","R-HSA-5658442","Regulation of RAS by GAPs",0.7457874246897598,0.9726910685202514,69.0,5.0,91110.95652173914,"5689, 8452, 9861, 22821, 153090"]
["Reactome","R-HSA-159230","Transport of the SLBP Dependant Mature mRNA",0.7471571008479571,0.9726910685202514,33.0,2.0,81106.93939393939,"8021, 23225"]
["Reactome","R-HSA-180910","Vpr-mediated nuclear import of PICs",0.74798731212362,0.9726910685202514,32.0,2.0,83283.78125,"8021, 23225"]
["Reactome","R-HSA-6783783","Interleukin-10 signaling",0.7480797970984006,0.9726910685202514,48.0,3.0,66780.3125,"1435, 3553, 3592"]
["Reactome","R-HSA-381119","Unfolded Protein Response (UPR)",0.7508246811532543,0.9726910685202514,88.0,5.0,57193.40909090909,"467, 1639, 3484, 10106, 10130"]
["Reactome","R-HSA-5619084","ABC transporter disorders",0.7527984185030847,0.9726910685202514,68.0,4.0,89371.07352941176,"79139, 5689, 9861, 653509"]
["Reactome","R-HSA-2022870","Chondroitin sulfate biosynthesis",0.7534100543264125,0.9726910685202514,21.0,2.0,167705.85714285713,"1462, 1634"]
["Reactome","R-HSA-381038","XBP1(S) activates chaperone genes",0.7539607741848421,0.9726910685202514,53.0,3.0,59775.67924528302,"1639, 10106, 10130"]
["Reactome","R-HSA-199220","Vitamin B5 (pantothenate) metabolism",0.7539674135973282,0.9726910685202514,17.0,1.0,85693.76470588235,"5168"]
["Reactome","R-HSA-191859","snRNP Assembly",0.7544877445133392,0.9726910685202514,52.0,3.0,69565.94230769231,"8021, 23225, 25929"]
["Reactome","R-HSA-194441","Metabolism of non-coding RNA",0.7544877445133392,0.9726910685202514,52.0,3.0,69565.94230769231,"8021, 23225, 25929"]
["Reactome","R-HSA-350562","Regulation of ornithine decarboxylase (ODC)",0.754583942003918,0.9726910685202514,51.0,3.0,67560.1568627451,"51582, 5689, 9861"]
["Reactome","R-HSA-8876725","Protein methylation",0.7550857575757903,0.9726910685202514,18.0,1.0,77614.33333333333,"254013"]
["Reactome","R-HSA-5668541","TNFR2 non-canonical NF-kB pathway",0.7554824225135038,0.9726910685202514,100.0,7.0,81732.41,"5689, 7187, 7292, 8764, 9020, 9861, 10673"]
["Reactome","R-HSA-391903","Eicosanoid ligand-binding receptors",0.7583439445421989,0.9726910685202514,15.0,1.0,115542.0,"11251"]
["Reactome","R-HSA-69601","Ubiquitin Mediated Degradation of Phosphorylated Cdc25A",0.7600572674883285,0.9726910685202514,53.0,3.0,63258.50943396227,"5689, 9861, 11200"]
["Reactome","R-HSA-69610","p53-Independent DNA Damage Response",0.7600572674883285,0.9726910685202514,53.0,3.0,63258.50943396227,"5689, 9861, 11200"]
["Reactome","R-HSA-69613","p53-Independent G1/S DNA damage checkpoint",0.7600572674883285,0.9726910685202514,53.0,3.0,63258.50943396227,"5689, 9861, 11200"]
["Reactome","R-HSA-982772","Growth hormone receptor signaling",0.7611742683154018,0.9726910685202514,25.0,2.0,123575.96,"8660, 9021"]
["Reactome","R-HSA-168274","Export of Viral Ribonucleoproteins from Nucleus",0.7616451905067216,0.9726910685202514,31.0,2.0,87106.35483870968,"8021, 23225"]
["Reactome","R-HSA-168333","NEP/NS2 Interacts with the Cellular Export Machinery",0.7618887555749594,0.9726910685202514,30.0,2.0,89998.83333333333,"8021, 23225"]
["Reactome","R-HSA-159227","Transport of the SLBP independent Mature mRNA",0.762328404873527,0.9726910685202514,32.0,2.0,83103.96875,"8021, 23225"]
["Reactome","R-HSA-450385","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA",0.7630384763756562,0.9726910685202514,17.0,1.0,85575.58823529411,"677"]
["Reactome","R-HSA-190872","Transport of connexons to the plasma membrane",0.7675961707070325,0.9726910685202514,19.0,1.0,70260.42105263157,"2697"]
["Reactome","R-HSA-977068","Termination of O-glycan biosynthesis",0.7682556656402499,0.9726910685202514,21.0,2.0,145048.90476190476,"6480, 4585"]
["Reactome","R-HSA-6814122","Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding",0.7685847642636423,0.9726910685202514,43.0,3.0,98789.44186046511,"9628, 2779, 2793"]
["Reactome","R-HSA-1236978","Cross-presentation of soluble exogenous antigens (endosomes)",0.7726320487176337,0.9726910685202514,50.0,3.0,68012.94,"5689, 9861, 9902"]
["KEGG Pathways","hsa00030","Pentose phosphate pathway",0.7734208590915912,0.9989248813013669,27.0,2.0,99175.25925925926,"229, 5214"]
["Reactome","R-HSA-8862803","Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models",0.7773027473888894,0.9726910685202514,22.0,2.0,127360.5,"831, 10018"]
["Reactome","R-HSA-8863678","Neurodegenerative Diseases",0.7773027473888894,0.9726910685202514,22.0,2.0,127360.5,"831, 10018"]
["KEGG Pathways","hsa04142","Lysosome",0.7774164683294242,0.9989248813013669,120.0,8.0,81401.275,"411, 1212, 1513, 1514, 3916, 9583, 10312, 22901"]
["Reactome","R-HSA-5654712","FRS-mediated FGFR4 signaling",0.7775026598776236,0.9726910685202514,22.0,2.0,126098.13636363637,"2264, 9965"]
["KEGG Pathways","hsa03020","RNA polymerase",0.7791010986824994,0.9989248813013669,29.0,1.0,33872.862068965514,"25885"]
["Reactome","R-HSA-450321","JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1",0.7793242263377437,0.9726910685202514,23.0,2.0,149441.52173913043,"6416, 64127"]
["Reactome","R-HSA-180746","Nuclear import of Rev protein",0.7814214602178264,0.9726910685202514,32.0,2.0,80495.6875,"8021, 23225"]
["Reactome","R-HSA-5654710","PI-3K cascade:FGFR3",0.7884961203691805,0.9726910685202514,18.0,2.0,194458.66666666666,"2261, 5295"]
["Reactome","R-HSA-168181","Toll Like Receptor 7/8 (TLR7/8) Cascade",0.7898167068862798,0.9726910685202514,93.0,9.0,141489.5806451613,"1846, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 64127"]
["Reactome","R-HSA-975155","MyD88 dependent cascade initiated on endosome",0.7898167068862798,0.9726910685202514,93.0,9.0,141489.5806451613,"1846, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 64127"]
["Reactome","R-HSA-430039","mRNA decay by 5' to 3' exoribonuclease",0.7913062133379081,0.9726910685202514,15.0,1.0,82457.6,"196513"]
["Reactome","R-HSA-1980145","Signaling by NOTCH2",0.7920859760740543,0.9726910685202514,33.0,3.0,130322.54545454546,"28514, 3714, 388585"]
["Reactome","R-HSA-163125","Post-translational modification: synthesis of GPI-anchored proteins",0.7922300111677083,0.9726910685202514,91.0,8.0,191194.5934065934,"4978, 1368, 5067, 50863, 84628, 146760, 161357, 349667"]
["Reactome","R-HSA-70263","Gluconeogenesis",0.7999856276357336,0.9726910685202514,32.0,2.0,74771.875,"229, 5567"]
["Reactome","R-HSA-190840","Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane",0.8014981576146605,0.9726910685202514,18.0,1.0,72214.11111111111,"2697"]
["Reactome","R-HSA-168271","Transport of Ribonucleoproteins into the Host Nucleus",0.8022249954297376,0.9726910685202514,30.0,2.0,86004.53333333334,"8021, 23225"]
["Reactome","R-HSA-446193","Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",0.8112830431133925,0.9726910685202514,78.0,7.0,178231.53846153847,"6480, 9945, 29926, 2762, 8869, 256281, 338596"]
["Reactome","R-HSA-69183","Processive synthesis on the lagging strand",0.813404334929164,0.9726910685202514,15.0,1.0,97076.2,"23649"]
["Reactome","R-HSA-5578749","Transcriptional regulation by small RNAs",0.8144258610911639,0.9726910685202514,100.0,4.0,43637.08,"8021, 8353, 23225, 27327"]
["Reactome","R-HSA-69473","G2/M DNA damage checkpoint",0.8144283799770985,0.9726910685202514,94.0,6.0,69474.01063829787,"2810, 7336, 8924, 9577, 11200, 116028"]
["Reactome","R-HSA-69229","Ubiquitin-dependent degradation of Cyclin D1",0.8147872508452245,0.9726910685202514,51.0,3.0,64361.27450980392,"595, 5689, 9861"]
["Reactome","R-HSA-75815","Ubiquitin-dependent degradation of Cyclin D",0.8147872508452245,0.9726910685202514,51.0,3.0,64361.27450980392,"595, 5689, 9861"]
["Reactome","R-HSA-4570464","SUMOylation of RNA binding proteins",0.8158740012271672,0.9726910685202514,47.0,3.0,73907.08510638298,"8021, 23225, 57332"]
["Reactome","R-HSA-1839117","Signaling by cytosolic FGFR1 fusion mutants",0.8169449540448672,0.9726910685202514,18.0,2.0,178042.66666666666,"5295, 11064"]
["Reactome","R-HSA-975138","TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",0.821626749413301,0.9726910685202514,91.0,9.0,143377.63736263735,"1846, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 64127"]
["Reactome","R-HSA-166658","Complement cascade",0.821666912192764,0.9726910685202514,44.0,3.0,135392.3409090909,"718, 1675, 5648"]
["Reactome","R-HSA-192456","Digestion of dietary lipid",0.8250326975637415,0.9726910685202514,15.0,1.0,76231.0,"3990"]
["Reactome","R-HSA-170822","Regulation of Glucokinase by Glucokinase Regulatory Protein",0.8256018596687582,0.9726910685202514,30.0,2.0,83820.36666666667,"8021, 23225"]
["Reactome","R-HSA-5621480","Dectin-2 family",0.8268050250576318,0.9726910685202514,24.0,2.0,100222.29166666667,"2534, 4585"]
["Reactome","R-HSA-75109","Triglyceride Biosynthesis",0.82733251947258,0.9726910685202514,78.0,7.0,127251.83333333333,"9663, 11332, 2180, 23205, 23305, 26027, 55326"]
["Reactome","R-HSA-168928","RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways",0.8280487898847007,0.9726910685202514,84.0,6.0,77495.26190476191,"1387, 3660, 4214, 7187, 7318, 8737"]
["KEGG Pathways","hsa05020","Prion diseases",0.8340652583402204,0.9989248813013669,35.0,3.0,144525.94285714286,"2534, 3553, 5567"]
["Reactome","R-HSA-6804757","Regulation of TP53 Degradation",0.8343124529963736,0.9726910685202514,35.0,3.0,108671.28571428571,"55615, 10000, 11200"]
["Reactome","R-HSA-392451","G beta:gamma signalling through PI3Kgamma",0.8401443943660866,0.9726910685202514,48.0,4.0,104847.27083333333,"2793, 5293, 5295, 10000"]
["KEGG Pathways","hsa04722","Neurotrophin signaling pathway",0.840943612334749,0.9989248813013669,126.0,13.0,146863.31746031746,"4908, 810, 10019, 627, 2889, 4214, 4804, 5293, 5295, 5580, 6196, 8660, 10000"]
["Reactome","R-HSA-556833","Metabolism of lipids and lipoproteins",0.8475999364204806,0.9726910685202514,794.0,74.0,115715.77078085643,"9612, 338, 5287, 6095, 9663, 10499, 10891, 11332, 29116, 51422, 55500, 196, 337, 348, 411, 590, 622, 1081, 1374, 1387, 1455, 1757, 2101, 2180, 2274, 2534, 2678, 3069, 3290, 3931, 3990, 3991, 4862, 5034, 5046, 5244, 5293, 5295, 5501, 5567, 5867, 6579, 6716, 7003, 8310, 8647, 8877, 9108, 9572, 9915, 11343, 22874, 22901, 23179, 23205, 23305, 23761, 25816, 25937, 26027, 26031, 26119, 26230, 29841, 50487, 54477, 55289, 55326, 57552, 80205, 340075, 388121, 646486, 100616211"]
["Reactome","R-HSA-389948","PD-1 signaling",0.8519634832664067,0.9726910685202514,21.0,1.0,42924.04761904762,"919"]
["Reactome","R-HSA-5654695","PI-3K cascade:FGFR2",0.8534546938771205,0.9726910685202514,23.0,3.0,222689.30434782608,"2252, 2263, 5295"]
["Reactome","R-HSA-390918","Peroxisomal lipid metabolism",0.8575124328407657,0.9726910685202514,29.0,2.0,72824.93103448275,"8310, 55289"]
["Reactome","R-HSA-389661","Glyoxylate metabolism and glycine degradation",0.8593450168702228,0.9726910685202514,25.0,2.0,118971.48,"1610, 2731"]
["KEGG Pathways","hsa00830","Retinol metabolism",0.8600160398620803,0.9989248813013669,63.0,5.0,90707.8253968254,"10170, 125, 216, 9249, 157506"]
["Reactome","R-HSA-5654741","Signaling by FGFR3",0.866066604762852,0.9726910685202514,40.0,4.0,181754.9,"2261, 2591, 5295, 6714"]
["Reactome","R-HSA-5633008","TP53 Regulates Transcription of Cell Death Genes",0.8695325727249842,0.9726910685202514,45.0,4.0,112444.95555555556,"317, 834, 1387, 8738"]
["Reactome","R-HSA-5654743","Signaling by FGFR4",0.8707026959109034,0.9726910685202514,41.0,4.0,175868.46341463414,"2264, 5295, 6714, 9965"]
["Reactome","R-HSA-156711","Polo-like kinase mediated events",0.8734773617188009,0.9726910685202514,17.0,1.0,59721.117647058825,"1063"]
["Reactome","R-HSA-70171","Glycolysis",0.8743516374617581,0.9726910685202514,32.0,2.0,64801.75,"229, 5214"]
["Reactome","R-HSA-933541","TRAF6 mediated IRF7 activation",0.8765552228457401,0.9726910685202514,35.0,2.0,57346.05714285714,"1387, 3660"]
["Reactome","R-HSA-8856825","Cargo recognition for clathrin-mediated endocytosis",0.8778076078030423,0.9726910685202514,98.0,10.0,141407.75510204083,"338, 154, 185, 1212, 1956, 2060, 7474, 11037, 26119, 85439"]
["KEGG Pathways","hsa04914","Progesterone-mediated oocyte maturation",0.8780702569600737,0.9989248813013669,85.0,9.0,169663.2,"8379, 107, 699, 5293, 5295, 5567, 6196, 10000, 196883"]
["KEGG Pathways","hsa00480","Glutathione metabolism",0.8783563273438146,0.9989248813013669,50.0,3.0,56046.52,"2678, 2878, 4258"]
["Reactome","R-HSA-1296065","Inwardly rectifying K+ channels",0.8790526893609751,0.9726910685202514,31.0,3.0,155828.38709677418,"2793, 3768, 3773"]
["Reactome","R-HSA-5625886","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3",0.8792667559401635,0.9726910685202514,62.0,2.0,46260.75806451613,"10499, 8353"]
["Reactome","R-HSA-442982","Ras activation uopn Ca2+ infux through NMDA receptor",0.881833912525399,0.9726910685202514,18.0,2.0,164425.05555555556,"2903, 2905"]
["KEGG Pathways","hsa05160","Hepatitis C",0.8826380073600172,0.9989248813013669,134.0,11.0,94651.5895522388,"1956, 5293, 5295, 5521, 5522, 7098, 7187, 8737, 9021, 10000, 24146"]
["Reactome","R-HSA-71387","Metabolism of carbohydrates",0.8835586435881727,0.9726910685202514,291.0,29.0,157972.22680412373,"8534, 2817, 5257, 8972, 216, 229, 411, 1462, 1634, 2331, 3038, 4060, 4958, 5214, 5567, 6382, 6513, 6518, 8021, 9394, 9435, 9957, 10090, 23225, 23563, 57818, 64131, 92126, 375790"]
["Reactome","R-HSA-168138","Toll Like Receptor 9 (TLR9) Cascade",0.8838979626308813,0.9726910685202514,97.0,10.0,144800.07216494845,"1846, 4205, 1848, 4214, 6196, 6416, 7098, 7099, 8411, 64127"]
["Reactome","R-HSA-2022928","HS-GAG biosynthesis",0.8840730699843266,0.9726910685202514,31.0,5.0,385715.06451612903,"2817, 6382, 9394, 9957, 375790"]
["Reactome","R-HSA-392518","Signal amplification",0.8841327607550435,0.9726910685202514,33.0,3.0,153504.9090909091,"2793, 6714, 10672"]
["Reactome","R-HSA-113510","E2F mediated regulation of DNA replication",0.8865578283138362,0.9726910685202514,34.0,3.0,104821.5294117647,"5925, 7027, 23649"]
["Reactome","R-HSA-379724","tRNA Aminoacylation",0.8880047353531579,0.9726910685202514,42.0,0.0,88069.78571428571,""]
["Reactome","R-HSA-5654719","SHC-mediated cascade:FGFR4",0.8880587883370953,0.9726910685202514,20.0,2.0,128581.45,"2264, 9965"]
["Reactome","R-HSA-1461973","Defensins",0.8904576679513962,0.9726910685202514,44.0,0.0,51663.22727272727,""]
["Reactome","R-HSA-5696400","Dual Incision in GG-NER",0.8906822818707403,0.9726910685202514,41.0,0.0,80732.9512195122,""]
["Reactome","R-HSA-6782315","tRNA modification in the nucleus and cytosol",0.8907636512035813,0.9726910685202514,41.0,0.0,72606.29268292683,""]
["Reactome","R-HSA-5368287","Mitochondrial translation",0.892486656197617,0.9726910685202514,92.0,0.0,50487.30434782609,""]
["Reactome","R-HSA-5696394","DNA Damage Recognition in GG-NER",0.8938489454365716,0.9726910685202514,38.0,0.0,68232.94736842105,""]
["Reactome","R-HSA-176187","Activation of ATR in response to replication stress",0.8957994754230554,0.9726910685202514,37.0,0.0,75973.48648648648,""]
["Reactome","R-HSA-5389840","Mitochondrial translation elongation",0.8958645531418776,0.9726910685202514,86.0,0.0,49942.36046511628,""]
["Reactome","R-HSA-72172","mRNA Splicing",0.8960574334542014,0.9726910685202514,192.0,0.0,67700.88541666667,""]
["Reactome","R-HSA-5419276","Mitochondrial translation termination",0.8964888294192725,0.9726910685202514,85.0,0.0,51909.31764705882,""]
["Reactome","R-HSA-5368286","Mitochondrial translation initiation",0.8965299688804204,0.9726910685202514,85.0,0.0,51450.69411764706,""]
["Reactome","R-HSA-3322077","Glycogen synthesis",0.8967568174928806,0.9726910685202514,15.0,0.0,292645.4,""]
["Reactome","R-HSA-5654733","Negative regulation of FGFR4 signaling",0.896878994964281,0.9726910685202514,31.0,3.0,174106.7741935484,"2264, 6714, 9965"]
["Reactome","R-HSA-73884","Base Excision Repair",0.8973170142790784,0.9726910685202514,37.0,0.0,60159.97297297297,""]
["Reactome","R-HSA-73933","Resolution of Abasic Sites (AP sites)",0.8973170142790784,0.9726910685202514,37.0,0.0,60159.97297297297,""]
["Reactome","R-HSA-68884","Mitotic Telophase/Cytokinesis",0.8976111370465205,0.9726910685202514,15.0,0.0,114662.0,""]
["Reactome","R-HSA-3295583","TRP channels",0.8977734104853178,0.9726910685202514,28.0,3.0,150529.5,"8737, 11035, 54795"]
["Reactome","R-HSA-450513","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA",0.8978289914157482,0.9726910685202514,16.0,0.0,67897.9375,""]
["Reactome","R-HSA-72163","mRNA Splicing - Major Pathway",0.8981794631702759,0.9726910685202514,184.0,0.0,67719.71195652174,""]
["Reactome","R-HSA-5682910","LGI-ADAM interactions",0.8986620091489561,0.9726910685202514,15.0,0.0,88424.86666666667,""]
["Reactome","R-HSA-6781827","Transcription-Coupled Nucleotide Excision Repair (TC-NER)",0.8988606353589105,0.9726910685202514,79.0,0.0,70071.74683544303,""]
["Reactome","R-HSA-69202","Cyclin E associated events during G1/S transition ",0.8994680046250809,0.9726910685202514,71.0,5.0,75466.66197183098,"595, 5689, 5925, 9861, 10000"]
["Reactome","R-HSA-8851708","Signaling by FGFR2 IIIa TM",0.8997273347018109,0.9726910685202514,19.0,1.0,70452.15789473684,"2263"]
["Reactome","R-HSA-69298","Association of licensing factors with the pre-replicative complex",0.9001971648307202,0.9726910685202514,15.0,0.0,80685.33333333333,""]
["Reactome","R-HSA-5358508","Mismatch Repair",0.9003861611525621,0.9726910685202514,15.0,0.0,72705.86666666667,""]
["Reactome","R-HSA-113418","Formation of the Early Elongation Complex",0.9004055887494116,0.9726910685202514,34.0,0.0,47662.26470588235,""]
["Reactome","R-HSA-167158","Formation of the HIV-1 Early Elongation Complex",0.9004055887494116,0.9726910685202514,34.0,0.0,47662.26470588235,""]
["Reactome","R-HSA-2162123","Synthesis of Prostaglandins (PG) and Thromboxanes (TX)",0.9004905052522736,0.9726910685202514,15.0,0.0,82669.53333333334,""]
["Reactome","R-HSA-1461957","Beta defensins",0.9007914447682706,0.9726910685202514,36.0,0.0,53181.63888888889,""]
["Reactome","R-HSA-937039","IRAK1 recruits IKK complex",0.9015636270365988,0.9726910685202514,15.0,0.0,71254.13333333333,""]
["Reactome","R-HSA-975144","IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation",0.9015636270365988,0.9726910685202514,15.0,0.0,71254.13333333333,""]
["Reactome","R-HSA-167238","Pausing and recovery of Tat-mediated HIV elongation",0.9021073837270907,0.9726910685202514,35.0,0.0,32470.6,""]
["Reactome","R-HSA-167243","Tat-mediated HIV elongation arrest and recovery",0.9021073837270907,0.9726910685202514,35.0,0.0,32470.6,""]
["Reactome","R-HSA-162710","Synthesis of glycosylphosphatidylinositol (GPI)",0.9030871748417755,0.9726910685202514,16.0,0.0,39677.5625,""]
["Reactome","R-HSA-975110","TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling",0.9033339087577236,0.9726910685202514,16.0,0.0,40078.9375,""]
["Reactome","R-HSA-389958","Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding",0.904592477208533,0.9726910685202514,32.0,0.0,42977.65625,""]
["Reactome","R-HSA-8856828","Clathrin-mediated endocytosis",0.904904419170087,0.9726910685202514,138.0,14.0,129952.10869565218,"338, 274, 154, 185, 273, 1212, 1956, 2060, 7474, 11037, 26119, 29993, 85439, 112574"]
["Reactome","R-HSA-8866652","Synthesis of active ubiquitin: roles of E1 and E2 enzymes",0.9049533047828562,0.9726910685202514,30.0,0.0,98121.63333333333,""]
["Reactome","R-HSA-170670","Adenylate cyclase inhibitory pathway",0.9052306935645029,0.9726910685202514,15.0,2.0,208425.2,"107, 196883"]
["Reactome","R-HSA-997269","Inhibition of adenylate cyclase pathway",0.9052306935645029,0.9726910685202514,15.0,2.0,208425.2,"107, 196883"]
["Reactome","R-HSA-72086","mRNA Capping",0.9054679770434287,0.9726910685202514,29.0,0.0,63703.96551724138,""]
["Reactome","R-HSA-75067","Processing of Capped Intronless Pre-mRNA",0.9061881393446092,0.9726910685202514,30.0,0.0,54769.13333333333,""]
["Reactome","R-HSA-109688","Cleavage of Growing Transcript in the Termination Region ",0.9063609688839614,0.9726910685202514,68.0,0.0,55754.16176470588,""]
["Reactome","R-HSA-73856","RNA Polymerase II Transcription Termination",0.9063609688839614,0.9726910685202514,68.0,0.0,55754.16176470588,""]
["Reactome","R-HSA-110314","Recognition of DNA damage by PCNA-containing replication complex",0.9069681802052956,0.9726910685202514,30.0,0.0,75235.6,""]
["Reactome","R-HSA-6782135","Dual incision in TC-NER",0.907363646487455,0.9726910685202514,66.0,0.0,71226.83333333333,""]
["Reactome","R-HSA-5601884","PIWI-interacting RNA (piRNA) biogenesis",0.9077570033369753,0.9726910685202514,29.0,0.0,55879.379310344826,""]
["Reactome","R-HSA-167160","RNA Pol II CTD phosphorylation and interaction with CE during HIV infection",0.9084555009282362,0.9726910685202514,27.0,0.0,66906.18518518518,""]
["Reactome","R-HSA-77075","RNA Pol II CTD phosphorylation and interaction with CE",0.9084555009282362,0.9726910685202514,27.0,0.0,66906.18518518518,""]
["Reactome","R-HSA-6782210","Gap-filling DNA repair synthesis and ligation in TC-NER",0.908960767873624,0.9726910685202514,65.0,0.0,62132.015384615384,""]
["Reactome","R-HSA-8852135","Protein ubiquitination",0.909841878402825,0.9726910685202514,62.0,0.0,74501.59677419355,""]
["Reactome","R-HSA-389957","Prefoldin mediated transfer of substrate  to CCT/TriC",0.9102550036883871,0.9726910685202514,28.0,0.0,42544.28571428572,""]
["Reactome","R-HSA-76061","RNA Polymerase III Transcription Initiation From Type 1 Promoter",0.9102952085984173,0.9726910685202514,28.0,0.0,45768.67857142857,""]
["Reactome","R-HSA-901042","Calnexin/calreticulin cycle",0.9104126854988297,0.9726910685202514,26.0,0.0,134960.46153846153,""]
["Reactome","R-HSA-6803529","FGFR2 alternative splicing",0.9115406801248607,0.9726910685202514,27.0,0.0,43019.444444444445,""]
["Reactome","R-HSA-1614635","Sulfur amino acid metabolism",0.9118985191279498,0.9726910685202514,25.0,0.0,119797.84,""]
["Reactome","R-HSA-76066","RNA Polymerase III Transcription Initiation From Type 2 Promoter",0.9119815101870724,0.9726910685202514,27.0,0.0,44274.74074074074,""]
["Reactome","R-HSA-72187","mRNA 3'-end processing",0.9125135545498942,0.9726910685202514,59.0,0.0,58449.64406779661,""]
["Reactome","R-HSA-203927","MicroRNA (miRNA) biogenesis",0.9126620950818461,0.9726910685202514,25.0,0.0,47518.08,""]
["KEGG Pathways","hsa00760","Nicotinate and nicotinamide metabolism",0.913257358121601,0.9989248813013669,24.0,0.0,155554.54166666666,""]
["Reactome","R-HSA-379716","Cytosolic tRNA aminoacylation",0.9151048939473264,0.9726910685202514,24.0,0.0,91803.54166666667,""]
["Reactome","R-HSA-5696397","Gap-filling DNA repair synthesis and ligation in GG-NER",0.9152727517835786,0.9726910685202514,25.0,0.0,70818.16,""]
["Reactome","R-HSA-110373","Resolution of AP sites via the multiple-nucleotide patch replacement pathway",0.9157749902325161,0.9726910685202514,24.0,0.0,76488.20833333333,""]
["Reactome","R-HSA-6784531","tRNA processing in the nucleus",0.9158811815062476,0.9726910685202514,58.0,4.0,74093.24137931035,"1653, 8021, 10940, 23225"]
["Reactome","R-HSA-156588","Glucuronidation",0.916342778408977,0.9726910685202514,24.0,0.0,77918.5,""]
["KEGG Pathways","hsa03430","Mismatch repair",0.9164668376711835,0.9989248813013669,23.0,0.0,150646.73913043478,""]
["Reactome","R-HSA-983170","Antigen Presentation: Folding, assembly and peptide loading of class I MHC",0.9164859745423162,0.9726910685202514,25.0,0.0,47595.52,""]
["Reactome","R-HSA-6781823","Formation of TC-NER Pre-Incision Complex",0.916708721559868,0.9726910685202514,54.0,0.0,59106.27777777778,""]
["KEGG Pathways","hsa03060","Protein export",0.9169878761075808,0.9989248813013669,23.0,0.0,89071.26086956522,""]
["Reactome","R-HSA-196741","Cobalamin (Cbl, vitamin B12) transport and metabolism",0.9173191780988392,0.9726910685202514,21.0,0.0,153340.7142857143,""]
["Reactome","R-HSA-69273","Cyclin A/B1 associated events during G2/M transition",0.9173790703477573,0.9726910685202514,22.0,0.0,91777.27272727272,""]
["Reactome","R-HSA-77289","Mitochondrial Fatty Acid Beta-Oxidation",0.917636879228867,0.9726910685202514,22.0,0.0,96163.18181818182,""]
["Reactome","R-HSA-389960","Formation of tubulin folding intermediates by CCT/TriC",0.9177232787732973,0.9726910685202514,25.0,0.0,39526.16,""]
["Reactome","R-HSA-1482801","Acyl chain remodelling of PS",0.9179841202923521,0.9726910685202514,22.0,0.0,167399.4090909091,""]
["Reactome","R-HSA-191273","Cholesterol biosynthesis",0.918049469289334,0.9726910685202514,24.0,0.0,58723.75,""]
["KEGG Pathways","hsa03040","Spliceosome",0.9181924322601389,0.9989248813013669,125.0,0.0,54806.616,""]
["KEGG Pathways","hsa00563","Glycosylphosphatidylinositol(GPI)-anchor biosynthesis",0.918768148634454,0.9989248813013669,24.0,0.0,52845.375,""]
["Reactome","R-HSA-72165","mRNA Splicing - Minor Pathway",0.9187870782212797,0.9726910685202514,53.0,0.0,37166.49056603773,""]
["Reactome","R-HSA-167242","Abortive elongation of HIV-1 transcript in the absence of Tat",0.9188317939517369,0.9726910685202514,24.0,0.0,29121.708333333332,""]
["Reactome","R-HSA-4641263","Regulation of FZD by ubiquitination",0.9189415923302591,0.9726910685202514,21.0,0.0,148229.09523809524,""]
["Reactome","R-HSA-429947","Deadenylation of mRNA",0.9189748720434039,0.9726910685202514,22.0,0.0,96120.09090909091,""]
["Reactome","R-HSA-140875","Common Pathway of Fibrin Clot Formation",0.9190819072379688,0.9726910685202514,22.0,0.0,168059.54545454544,""]
["Reactome","R-HSA-164938","Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters",0.9193937272895462,0.9726910685202514,22.0,0.0,78568.13636363637,""]
["Reactome","R-HSA-901032","ER Quality Control Compartment (ERQC)",0.9195268288052858,0.9726910685202514,21.0,0.0,163700.42857142858,""]
["Reactome","R-HSA-6804115","TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain",0.919825505300897,0.9726910685202514,21.0,0.0,104888.42857142857,""]
["Reactome","R-HSA-379726","Mitochondrial tRNA aminoacylation",0.9200462932473517,0.9726910685202514,21.0,0.0,91890.76190476191,""]
["Reactome","R-HSA-174048","APC/C:Cdc20 mediated degradation of Cyclin B",0.9201178142683153,0.9726910685202514,22.0,0.0,69272.04545454546,""]
["Reactome","R-HSA-77595","Processing of Intronless Pre-mRNAs",0.9207922109630144,0.9726910685202514,21.0,0.0,61920.0,""]
["Reactome","R-HSA-6799198","Complex I biogenesis",0.9213869566193306,0.9726910685202514,48.0,0.0,51514.645833333336,""]
["Reactome","R-HSA-5651801","PCNA-Dependent Long Patch Base Excision Repair",0.9214929137650647,0.9726910685202514,21.0,0.0,72240.09523809524,""]
["Reactome","R-HSA-1660514","Synthesis of PIPs at the Golgi membrane",0.9225668183371896,0.9726910685202514,19.0,0.0,131574.26315789475,""]
["Reactome","R-HSA-141405","Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components",0.9227766692613593,0.9726910685202514,19.0,0.0,116412.84210526316,""]
["Reactome","R-HSA-141430","Inactivation of APC/C via direct inhibition of the APC/C complex",0.9227766692613593,0.9726910685202514,19.0,0.0,116412.84210526316,""]
["Reactome","R-HSA-140837","Intrinsic Pathway of Fibrin Clot Formation",0.9228568620206615,0.9726910685202514,21.0,0.0,66792.80952380953,""]
["Reactome","R-HSA-167169","HIV Transcription Elongation",0.9229789201170081,0.9726910685202514,47.0,0.0,44659.89361702128,""]
["Reactome","R-HSA-167200","Formation of HIV-1 elongation complex containing HIV-1 Tat",0.9229789201170081,0.9726910685202514,47.0,0.0,44659.89361702128,""]
["Reactome","R-HSA-167246","Tat-mediated elongation of the HIV-1 transcript",0.9229789201170081,0.9726910685202514,47.0,0.0,44659.89361702128,""]
["Reactome","R-HSA-181429","Serotonin Neurotransmitter Release Cycle",0.9231255847719093,0.9726910685202514,17.0,2.0,226067.29411764705,"10815, 8499"]
["KEGG Pathways","hsa00630","Glyoxylate and dicarboxylate metabolism",0.9232022960550033,0.9989248813013669,18.0,0.0,207030.27777777778,""]
["Reactome","R-HSA-171306","Packaging Of Telomere Ends",0.9238078302150201,0.9726910685202514,47.0,0.0,46129.17021276596,""]
["KEGG Pathways","hsa03420","Nucleotide excision repair",0.9242268069516109,0.9989248813013669,44.0,0.0,126611.29545454546,""]
["Reactome","R-HSA-3296482","Defects in vitamin and cofactor metabolism",0.924790345299338,0.9726910685202514,17.0,0.0,198931.70588235295,""]
["KEGG Pathways","hsa00380","Tryptophan metabolism",0.9249174165862337,0.9989248813013669,42.0,0.0,138174.2142857143,""]
["KEGG Pathways","hsa00860","Porphyrin and chlorophyll metabolism",0.9262222012245883,0.9989248813013669,43.0,0.0,79650.09302325582,""]
["Reactome","R-HSA-3247509","Chromatin modifying enzymes",0.9266938943373428,0.9726910685202514,270.0,22.0,106264.91481481481,"9612, 10499, 29943, 595, 1387, 5077, 6597, 6603, 8353, 11091, 11143, 22992, 23030, 23522, 55250, 55352, 57492, 63976, 64754, 84159, 84678, 117143"]
["Reactome","R-HSA-4839726","Chromatin organization",0.9266938943373428,0.9726910685202514,270.0,22.0,106264.91481481481,"9612, 10499, 29943, 595, 1387, 5077, 6597, 6603, 8353, 11091, 11143, 22992, 23030, 23522, 55250, 55352, 57492, 63976, 64754, 84159, 84678, 117143"]
["Reactome","R-HSA-8866654","E3 ubiquitin ligases ubiquitinate target proteins",0.9267615830200233,0.9726910685202514,42.0,0.0,56375.95238095238,""]
["Reactome","R-HSA-5656121","Translesion synthesis by POLI",0.926977547037853,0.9726910685202514,17.0,0.0,109285.82352941176,""]
["Reactome","R-HSA-205043","NRIF signals cell death from the nucleus",0.9269828223694647,0.9726910685202514,15.0,1.0,68251.73333333334,"4804"]
["Reactome","R-HSA-5655862","Translesion synthesis by POLK",0.9269836975995145,0.9726910685202514,17.0,0.0,109040.0,""]
["Reactome","R-HSA-176407","Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase",0.9270123298964289,0.9726910685202514,18.0,0.0,77962.77777777778,""]
["KEGG Pathways","hsa00100","Steroid biosynthesis",0.9272200750272593,0.9989248813013669,19.0,0.0,60550.21052631579,""]
["KEGG Pathways","hsa00360","Phenylalanine metabolism",0.9273231203363063,0.9989248813013669,17.0,0.0,130436.41176470589,""]
["Reactome","R-HSA-176412","Phosphorylation of the APC/C",0.9273258929470763,0.9726910685202514,18.0,0.0,76328.22222222222,""]
["KEGG Pathways","hsa00970","Aminoacyl-tRNA biosynthesis",0.9275836742532955,0.9989248813013669,41.0,0.0,84642.39024390244,""]
["Reactome","R-HSA-73780","RNA Polymerase III Chain Elongation",0.9281446678862854,0.9726910685202514,18.0,0.0,34804.055555555555,""]
["Reactome","R-HSA-1170546","Prolactin receptor signaling",0.9283640624759393,0.9726910685202514,16.0,0.0,124781.1875,""]
["Reactome","R-HSA-450604","KSRP (KHSRP) binds and destabilizes mRNA",0.9285552720295812,0.9726910685202514,18.0,0.0,53346.72222222222,""]
["KEGG Pathways","hsa00450","Selenocompound metabolism",0.9287974470116483,0.9989248813013669,17.0,0.0,99407.17647058824,""]
["Reactome","R-HSA-110312","Translesion synthesis by REV1",0.9288946495325788,0.9726910685202514,16.0,0.0,111643.0,""]
["Reactome","R-HSA-1482922","Acyl chain remodelling of PI",0.9295989891891561,0.9726910685202514,17.0,0.0,165465.76470588235,""]
["Reactome","R-HSA-156581","Methylation",0.9301584461620223,0.9726910685202514,15.0,0.0,202127.8,""]
["KEGG Pathways","hsa00270","Cysteine and methionine metabolism",0.9310331448347999,0.9989248813013669,36.0,0.0,143214.41666666666,""]
["KEGG Pathways","hsa00511","Other glycan degradation",0.9310941578203551,0.9989248813013669,16.0,0.0,93165.875,""]
["Reactome","R-HSA-189445","Metabolism of porphyrins",0.9323034230723346,0.9726910685202514,17.0,0.0,45069.17647058824,""]
["KEGG Pathways","hsa00120","Primary bile acid biosynthesis",0.9323132944846536,0.9989248813013669,16.0,0.0,81257.9375,""]
["Reactome","R-HSA-429958","mRNA decay by 3' to 5' exoribonuclease",0.9339946550649574,0.9726910685202514,16.0,0.0,38642.8125,""]
["KEGG Pathways","hsa00900","Terpenoid backbone biosynthesis",0.9351436896669502,0.9989248813013669,15.0,0.0,64730.26666666667,""]
["KEGG Pathways","hsa00040","Pentose and glucuronate interconversions",0.9363698833290164,0.9989248813013669,32.0,0.0,78882.09375,""]
["Reactome","R-HSA-2682334","EPH-Ephrin signaling",0.9373055640650607,0.9751878451300583,94.0,11.0,245173.06382978722,"2049, 1212, 1946, 2534, 4627, 6714, 7410, 8440, 8874, 8997, 10451"]
["Reactome","R-HSA-5683826","Surfactant metabolism",0.9382010720955232,0.9751878451300583,30.0,3.0,128384.36666666667,"152, 221395, 653509"]
["KEGG Pathways","hsa00053","Ascorbate and aldarate metabolism",0.942759028412101,0.9989248813013669,26.0,0.0,75322.46153846153,""]
["Reactome","R-HSA-5663202","Diseases of signal transduction",0.9438592157379515,0.9782471833295548,367.0,39.0,149113.9782016349,"4088, 9612, 6934, 9759, 28514, 1499, 23462, 55615, 324, 1387, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2308, 2534, 3714, 4089, 5293, 5295, 5689, 5947, 6714, 8660, 9542, 9861, 9965, 10000, 10018, 11064, 22821, 23493, 29851, 50846, 153090, 388585"]
["KEGG Pathways","hsa00510","N-Glycan biosynthesis",0.9527889302469136,0.9989248813013669,49.0,5.0,261549.55102040817,"6480, 1603, 4121, 11320, 57134"]
["KEGG Pathways","hsa00330","Arginine and proline metabolism",0.9549992559315018,0.9989248813013669,54.0,5.0,122863.70370370371,"445, 1610, 4842, 4942, 8974"]
["Reactome","R-HSA-168179","Toll Like Receptor TLR1:TLR2 Cascade",0.9564858235842353,0.9837879879110926,97.0,10.0,140890.82474226804,"1846, 4205, 1848, 4214, 6196, 6416, 7099, 10333, 64127, 653509"]
["Reactome","R-HSA-181438","Toll Like Receptor 2 (TLR2) Cascade",0.9564858235842353,0.9837879879110926,97.0,10.0,140890.82474226804,"1846, 4205, 1848, 4214, 6196, 6416, 7099, 10333, 64127, 653509"]
["Reactome","R-HSA-5654716","Downstream signaling of activated FGFR4",0.9680034849303336,0.9928005381496117,27.0,3.0,153693.55555555556,"2264, 5295, 9965"]
["Reactome","R-HSA-2979096","NOTCH2 Activation and Transmission of Signal to the Nucleus",0.9690270412703109,0.992908276410622,21.0,2.0,130755.95238095238,"28514, 3714"]
["KEGG Pathways","hsa05214","Glioma",0.972710099656194,0.9989248813013669,64.0,7.0,137306.953125,"810, 595, 1956, 5293, 5295, 5925, 10000"]
["Reactome","R-HSA-1236975","Antigen processing-Cross presentation",0.9727989989383202,0.994768440805043,99.0,7.0,74657.25252525252,"1514, 4688, 5689, 7099, 9861, 9902, 10333"]
["Reactome","R-HSA-1855204","Synthesis of IP3 and IP4 in the cytosol",0.9736031548304676,0.994768440805043,27.0,3.0,151529.62962962964,"3706, 5330, 9651"]
["KEGG Pathways","hsa04012","ErbB signaling pathway",0.9774513837801642,0.9989248813013669,87.0,10.0,184897.83908045976,"1956, 2066, 4690, 5293, 5295, 6416, 6714, 8440, 9542, 10000"]
["Reactome","R-HSA-3772470","Negative regulation of TCF-dependent signaling by WNT ligand antagonists",0.9787230922130676,0.9974352660856232,15.0,2.0,188011.33333333334,"7474, 50964"]
["Reactome","R-HSA-211935","Fatty acids",0.9831214065453526,0.9983895976404846,15.0,1.0,53745.26666666667,"66002"]
["KEGG Pathways","hsa04962","Vasopressin-regulated water reabsorption",0.9867634053905617,0.9989248813013669,44.0,4.0,127749.29545454546,"1639, 2778, 5567, 90993"]
["KEGG Pathways","hsa04320","Dorso-ventral axis formation",0.9878685857005078,0.9989248813013669,24.0,3.0,178246.45833333334,"1956, 2114, 2120"]
["Reactome","R-HSA-187706","Signalling to p38 via RIT and RIN",0.9911992406190074,0.9983895976404846,247.0,27.0,155343.54655870446,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]
["Reactome","R-HSA-1638091","Heparan sulfate/heparin (HS-GAG) metabolism",0.9931524970531335,0.9983895976404846,55.0,8.0,293822.7090909091,"2817, 1462, 1634, 6382, 9394, 9957, 64131, 375790"]
["KEGG Pathways","hsa00250","Alanine, aspartate and glutamate metabolism",0.9962679239364026,0.9989248813013669,32.0,3.0,127398.34375,"9945, 445, 2572"]
["KEGG Pathways","hsa05211","Renal cell carcinoma",0.9971409049037377,0.9989248813013669,69.0,8.0,161605.5072463768,"7424, 1387, 2889, 5293, 5295, 6513, 9915, 10000"]
["Reactome","R-HSA-2404192","Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)",0.9980346577344974,0.9983895976404846,297.0,32.0,149159.25252525252,"2675, 1846, 51422, 57521, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5295, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 55437, 64121, 153090"]
["Reactome","R-HSA-211976","Endogenous sterols",0.9980621649884527,0.9983895976404846,27.0,3.0,128624.81481481482,"10499, 196, 9915"]
["Reactome","R-HSA-5684996","MAPK1/MAPK3 signaling",0.9981230907883576,0.9983895976404846,249.0,27.0,152612.5421686747,"2675, 1846, 80824, 1847, 1848, 1956, 2066, 2252, 2260, 2261, 2263, 2264, 2534, 2668, 2674, 2903, 2905, 5689, 6714, 8452, 8660, 9542, 9861, 9965, 11221, 22821, 153090"]

{"sheet":"STENvNINF Hypo","index":1,"n_rows":1287,"n_cols":9,"rows_kept":1287,"cut":false,"hidden":false,"merged":[]}
["Database","Geneset_ID","Description","pvalue","padj","N_background","N_observed","Average_gene_length","EntrezID_set"]
["Reactome","R-HSA-445355","Smooth Muscle Contraction",3.7541632851011803E-6,0.004058250511194376,34.0,11.0,112482.0294117647,"4638, 800, 59, 4629, 4637, 7171, 8291, 10174, 10627, 25802, 29895"]
["KEGG Pathways","hsa05414","Dilated cardiomyopathy",8.631428879222357E-6,0.0015939571678224036,90.0,23.0,218753.6222222222,"109, 115, 6445, 6546, 7042, 108, 111, 153, 488, 779, 781, 782, 1674, 3675, 3678, 3679, 3688, 3908, 4000, 4634, 6442, 7171, 9254"]
["KEGG Pathways","hsa04510","Focal adhesion",1.5550801637291743E-5,0.0015939571678224036,200.0,42.0,166866.095,"87, 1282, 1284, 4638, 5747, 9564, 81, 595, 858, 5154, 5295, 5500, 7058, 857, 1277, 1292, 1499, 1956, 3082, 3371, 3480, 3675, 3678, 3679, 3688, 3908, 3911, 5058, 5155, 5159, 5602, 5879, 6655, 7057, 7060, 7143, 7148, 7791, 8503, 10627, 29895, 55742"]
["KEGG Pathways","hsa04810","Regulation of actin cytoskeleton",3.08191732226088E-5,0.0018738505567373357,212.0,41.0,160571.74528301886,"8874, 87, 4627, 4638, 5747, 9564, 81, 623, 2246, 5154, 5295, 5500, 624, 1956, 2248, 2254, 2255, 2768, 2934, 3675, 3678, 3679, 3682, 3688, 5058, 5155, 5159, 5305, 5879, 6655, 8503, 9138, 9965, 10458, 10627, 22800, 23191, 26230, 29895, 54434, 55740"]
["KEGG Pathways","hsa05410","Hypertrophic cardiomyopathy (HCM)",3.656293769243582E-5,0.0018738505567373357,83.0,20.0,195575.53012048194,"6445, 6546, 7042, 51422, 488, 779, 781, 782, 1636, 1674, 3675, 3678, 3679, 3688, 3908, 4000, 4634, 6442, 7171, 9254"]
["KEGG Pathways","hsa05412","Arrhythmogenic right ventricular cardiomyopathy (ARVC)",6.335714735798472E-5,0.0025976430416773735,74.0,20.0,286059.8918918919,"87, 81, 6445, 6546, 488, 779, 781, 782, 1000, 1495, 1499, 1674, 3675, 3678, 3679, 3688, 3908, 4000, 6442, 9254"]
["Reactome","R-HSA-397014","Muscle contraction",1.2957703869537982E-4,0.0700363894148528,204.0,36.0,168555.26470588235,"4638, 800, 818, 1760, 3708, 6546, 28996, 59, 477, 486, 488, 489, 779, 781, 782, 815, 845, 1674, 3777, 4621, 4629, 4634, 4637, 4878, 6588, 7171, 7431, 8291, 9254, 10174, 10627, 25802, 29895, 30818, 51305, 100616453"]
["KEGG Pathways","hsa04512","ECM-receptor interaction",1.549136890813417E-4,0.005292884376945841,84.0,21.0,158047.90476190476,"1282, 1284, 7058, 948, 960, 1277, 1292, 2811, 2815, 3371, 3675, 3678, 3679, 3688, 3908, 3911, 6383, 7057, 7060, 7143, 7148"]
["KEGG Pathways","hsa04010","MAPK signaling pathway",2.7461280209003825E-4,0.007183647013074927,267.0,45.0,161743.3670411985,"8912, 1843, 2246, 5154, 6196, 7042, 9693, 356, 627, 779, 781, 782, 1847, 1956, 2248, 2254, 2255, 2353, 2768, 3164, 3553, 4208, 4214, 4616, 4790, 5058, 5155, 5159, 5536, 5602, 5606, 5608, 5879, 5921, 6655, 6788, 7186, 7867, 8398, 8911, 9254, 9448, 9965, 22800, 51776"]
["Reactome","R-HSA-416482","G alpha (12/13) signalling events",3.113348188217122E-4,0.10753044853035987,87.0,20.0,176694.06896551725,"8874, 29, 5295, 9828, 27237, 55160, 2768, 5364, 5879, 6655, 7204, 8503, 9138, 9181, 10276, 11214, 23263, 26230, 57580, 59345"]
["Reactome","R-HSA-109582","Hemostasis",4.1656371711093867E-4,0.10753044853035987,634.0,81.0,138547.49369085173,"87, 5575, 5099, 5747, 9564, 10938, 81, 285, 832, 928, 1607, 3705, 3708, 5154, 5295, 5590, 5660, 6404, 6546, 7042, 7123, 8527, 9948, 10630, 23414, 30846, 55619, 2, 152, 284, 488, 489, 747, 857, 948, 960, 1062, 1277, 1437, 1794, 2768, 2811, 2815, 3082, 3675, 3678, 3688, 3699, 3700, 3779, 3797, 3937, 4072, 5023, 5104, 5136, 5138, 5155, 5624, 5657, 5739, 5879, 6383, 7057, 7078, 7465, 7804, 7975, 8140, 8165, 8503, 8795, 9123, 10335, 11343, 23764, 25970, 51097, 51317, 59345, 100616453"]
["Reactome","R-HSA-193704","p75 NTR receptor-mediated signalling",5.96838752249916E-4,0.10753044853035987,97.0,20.0,139666.82474226804,"8874, 29, 4792, 9828, 27237, 55160, 4790, 5879, 6655, 6868, 7204, 9138, 9181, 10276, 11214, 23263, 26230, 57142, 57580, 84894"]
["Reactome","R-HSA-70171","Glycolysis",9.154118234562182E-4,0.1265472559198557,32.0,7.0,64801.75,"3098, 3101, 5208, 5209, 5210, 5214, 5224"]
["Reactome","R-HSA-6785807","Interleukin-4 and 13 signaling",9.365199328018922E-4,0.1265472559198557,110.0,21.0,154282.24545454545,"595, 598, 3091, 5295, 356, 948, 2309, 2353, 3082, 3553, 3596, 3662, 3688, 3726, 3911, 6624, 6772, 7133, 7291, 7431, 58480"]
["KEGG Pathways","hsa04020","Calcium signaling pathway",0.0010766563032551147,0.024523838018588724,176.0,35.0,202923.1875,"4638, 8912, 109, 115, 623, 818, 1909, 1910, 3707, 3708, 6546, 108, 153, 154, 488, 489, 624, 779, 815, 886, 1956, 2906, 3274, 3357, 3363, 5023, 5136, 5159, 5257, 5333, 6865, 8877, 8911, 23236, 51196"]
["Reactome","R-HSA-163560","Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis",0.0012583462932308552,0.13160089375109624,20.0,6.0,85166.45,"5500, 857, 2172, 5346, 11343, 51099"]
["Reactome","R-HSA-982772","Growth hormone receptor signaling",0.0013299918873934296,0.13160089375109624,25.0,7.0,123575.96,"5618, 6776, 3667, 6772, 6777, 6868, 25970"]
["Reactome","R-HSA-166520","Signalling by NGF",0.001339139529382108,0.13160089375109624,474.0,67.0,152808.34810126582,"8874, 29, 5575, 5747, 153090, 109, 115, 818, 1843, 2246, 3708, 4792, 5046, 5154, 5295, 6196, 9693, 9828, 22821, 27237, 55160, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 4208, 4790, 5136, 5155, 5159, 5305, 5536, 5690, 5879, 5921, 6655, 6868, 7204, 7867, 8503, 9048, 9138, 9181, 9965, 10276, 11214, 23112, 23263, 26230, 51332, 57142, 57580, 57731, 84894"]
["Reactome","R-HSA-193648","NRAGE signals death through JNK",0.0016524115335967615,0.14885473898484158,59.0,15.0,174894.3220338983,"8874, 29, 9828, 27237, 55160, 5879, 6655, 7204, 9138, 9181, 10276, 11214, 23263, 26230, 57580"]
["Reactome","R-HSA-5627123","RHO GTPases activate PAKs",0.002092551865054268,0.17400373585566645,22.0,7.0,127827.09090909091,"4627, 4638, 5500, 4629, 4637, 5058, 5879"]
["Reactome","R-HSA-186797","Signaling by PDGF",0.0024336143686061818,0.18790979517594875,380.0,55.0,153788.91315789474,"1282, 1284, 5575, 5747, 9564, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 6776, 7058, 8440, 9693, 22821, 108, 111, 284, 815, 1027, 1292, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 5136, 5155, 5159, 5305, 5536, 5690, 5782, 5921, 6772, 6777, 7057, 7060, 8503, 9048, 9965, 23112, 51332, 57731"]
["Reactome","R-HSA-194840","Rho GTPase cycle",0.002616814659963049,0.18858510982800372,139.0,27.0,193870.48920863308,"8874, 29, 90627, 9828, 27237, 55160, 93663, 116984, 2, 1123, 5879, 6655, 7204, 9138, 9181, 10144, 10276, 10395, 11214, 23092, 23263, 26230, 57580, 58480, 83478, 94134, 143872"]
["KEGG Pathways","hsa05200","Pathways in cancer",0.0028580753149994227,0.05859054395748817,326.0,52.0,178519.0736196319,"1282, 1284, 1488, 2034, 4088, 5747, 595, 598, 861, 2246, 3091, 4792, 5154, 5295, 6776, 7042, 356, 1021, 1027, 1495, 1499, 1956, 2113, 2248, 2254, 2255, 2353, 2736, 2950, 3082, 3480, 3675, 3688, 3908, 3911, 4790, 5155, 5159, 5602, 5879, 5914, 6655, 6772, 6777, 7186, 7474, 7477, 8324, 8503, 9618, 9915, 9965"]
["Reactome","R-HSA-375170","CDO in myogenesis",0.003128017967009383,0.19890514249042018,29.0,9.0,336057.1724137931,"4209, 1000, 1495, 1499, 4208, 5608, 6925, 6929, 9043"]
["Reactome","R-HSA-525793","Myogenesis",0.003128017967009383,0.19890514249042018,29.0,9.0,336057.1724137931,"4209, 1000, 1495, 1499, 4208, 5608, 6925, 6929, 9043"]
["Reactome","R-HSA-5625900","RHO GTPases activate CIT",0.0035623701225935955,0.21394011680687094,17.0,5.0,83406.94117647059,"4627, 1027, 4629, 4637, 5879"]
["Reactome","R-HSA-5578775","Ion homeostasis",0.004108402679964694,0.23374648931799125,55.0,12.0,157359.85454545455,"818, 1760, 3708, 6546, 477, 486, 488, 489, 815, 845, 6588, 100616453"]
["KEGG Pathways","hsa05220","Chronic myeloid leukemia",0.004205495361943462,0.07837514083621908,73.0,15.0,155967.12328767125,"1488, 4088, 595, 598, 861, 4792, 5295, 6776, 7042, 1021, 1027, 4790, 6655, 6777, 8503"]
["Reactome","R-HSA-3928664","Ephrin signaling",0.004846575401304171,0.25048704009199263,18.0,6.0,178052.11111111112,"8874, 8440, 2047, 5058, 5879, 10627"]
["Reactome","R-HSA-449147","Signaling by Interleukins",0.004866075709465166,0.25048704009199263,520.0,64.0,135231.47115384616,"5747, 153090, 595, 598, 818, 1843, 2246, 3091, 3603, 5154, 5295, 6776, 9693, 22821, 57161, 284, 356, 815, 948, 1435, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2353, 2906, 3082, 3553, 3556, 3596, 3662, 3667, 3688, 3726, 3911, 4790, 5155, 5159, 5536, 5608, 5657, 5690, 5921, 6352, 6363, 6624, 6772, 6777, 7133, 7291, 7431, 8503, 9048, 9173, 9965, 11009, 51332, 57731, 58480, 79155, 132014"]
["KEGG Pathways","hsa04062","Chemokine signaling pathway",0.005406833491358936,0.09236673881071515,188.0,28.0,134087.414893617,"5747, 9564, 109, 115, 4792, 5295, 5590, 108, 111, 1236, 1794, 2309, 4790, 5058, 5879, 6352, 6363, 6387, 6655, 6772, 6777, 8503, 23236, 26230, 56288, 57580, 59345, 131890"]
["Reactome","R-HSA-140837","Intrinsic Pathway of Fibrin Clot Formation",0.005424040649406994,0.26651763372768,21.0,5.0,66792.80952380953,"2, 2811, 2815, 5104, 5624"]
["Reactome","R-HSA-446353","Cell-extracellular matrix interactions",0.0058180156305860506,0.2727933317030207,17.0,5.0,100431.70588235294,"87, 54751, 55679, 3688, 10979"]
["Reactome","R-HSA-1839117","Signaling by cytosolic FGFR1 fusion mutants",0.006225816575823932,0.2727933317030207,18.0,6.0,178042.66666666666,"5295, 6776, 1523, 6772, 6777, 9208"]
["Reactome","R-HSA-1839124","FGFR1 mutant receptor activation",0.00652852106533762,0.2727933317030207,31.0,8.0,148091.4193548387,"2246, 5295, 6776, 1523, 2254, 6772, 6777, 9208"]
["Reactome","R-HSA-76002","Platelet activation, signaling and aggregation",0.006561171715336298,0.2727933317030207,274.0,38.0,149884.78467153283,"87, 5099, 5747, 9564, 81, 928, 1607, 3708, 5154, 5295, 5590, 5660, 7042, 7123, 8527, 9948, 10630, 2, 152, 747, 948, 1277, 1437, 2768, 2811, 2815, 3082, 3699, 3700, 3937, 5155, 5879, 7057, 7078, 8503, 11343, 51097, 59345"]
["Reactome","R-HSA-5654687","Downstream signaling of activated FGFR1",0.007205052002461595,0.278166471952178,31.0,8.0,192767.48387096773,"2246, 5295, 23768, 2248, 2254, 2255, 2549, 23769"]
["Reactome","R-HSA-1236394","Signaling by ERBB4",0.008032123123723076,0.2994043136808498,43.0,10.0,235212.60465116278,"5295, 6776, 1956, 2099, 2670, 6285, 6387, 6868, 10413, 11059"]
["Reactome","R-HSA-5655302","Signaling by FGFR1 in disease",0.008693947999239268,0.3076997161717564,38.0,9.0,142464.68421052632,"2246, 5295, 6776, 1523, 2254, 2549, 6772, 6777, 9208"]
["Reactome","R-HSA-204998","Cell death signalling via NRAGE, NRIF and NADE",0.008840430484421315,0.3076997161717564,75.0,15.0,148395.25333333333,"8874, 29, 9828, 27237, 55160, 5879, 6655, 7204, 9138, 9181, 10276, 11214, 23263, 26230, 57580"]
["KEGG Pathways","hsa05222","Small cell lung cancer",0.009004652200298877,0.1419964385431746,85.0,17.0,160193.11764705883,"1282, 1284, 5747, 595, 598, 4792, 5295, 1021, 1027, 3675, 3688, 3908, 3911, 4790, 7186, 8503, 9618"]
["Reactome","R-HSA-400206","Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)",0.009108594743289736,0.3076997161717564,124.0,20.0,138386.60483870967,"9612, 51586, 196, 211, 948, 2274, 3992, 4862, 7003, 7004, 7005, 9915, 10413, 10499, 23389, 26230, 27063, 27242, 29841, 57491"]
["Reactome","R-HSA-186763","Downstream signal transduction",0.010090785811756329,0.31680542484364793,350.0,48.0,151788.7257142857,"5575, 5747, 9564, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 6776, 8440, 9693, 22821, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 5136, 5155, 5159, 5305, 5536, 5690, 5921, 6772, 6777, 8503, 9048, 9965, 23112, 51332, 57731"]
["Reactome","R-HSA-1251985","Nuclear signaling by ERBB4",0.010472080623841274,0.31680542484364793,25.0,7.0,291679.64,"6776, 2099, 2670, 6285, 6387, 6868, 10413"]
["Reactome","R-HSA-445144","Signal transduction by L1",0.01055041192818809,0.31680542484364793,21.0,6.0,157451.38095238095,"1956, 3678, 3688, 5058, 5879, 8829"]
["Reactome","R-HSA-1280215","Cytokine Signaling in Immune system",0.011767736400282992,0.3382580357315194,743.0,81.0,121382.24091520862,"5747, 153090, 595, 598, 818, 1843, 2246, 3091, 3603, 5154, 5295, 5618, 6776, 9693, 22821, 57161, 284, 356, 684, 815, 948, 958, 960, 1435, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2353, 2906, 3082, 3394, 3553, 3556, 3596, 3662, 3667, 3688, 3726, 3911, 4790, 4982, 5155, 5159, 5536, 5608, 5657, 5690, 5921, 6352, 6363, 6624, 6672, 6772, 6777, 6868, 7133, 7186, 7291, 7431, 8503, 8995, 9048, 9173, 9965, 9966, 11009, 23225, 23279, 23321, 25970, 51332, 57731, 58480, 79155, 132014, 163351, 317649"]
["Reactome","R-HSA-194315","Signaling by Rho GTPases",0.011890661755594579,0.3382580357315194,433.0,53.0,140442.35103926098,"8874, 4627, 29, 4638, 5747, 8379, 90627, 91010, 5500, 9828, 27237, 55160, 93663, 116984, 2, 752, 1027, 1062, 1123, 1495, 1499, 3688, 4085, 4629, 4637, 4688, 5058, 5879, 6655, 7204, 9138, 9181, 10144, 10276, 10395, 10458, 10499, 10971, 11214, 23081, 23092, 23191, 23263, 23279, 26230, 55839, 55920, 57580, 58480, 83478, 94134, 143872, 147841"]
["Reactome","R-HSA-5654689","PI-3K cascade:FGFR1",0.012409776893949561,0.3439735595476789,21.0,6.0,179964.47619047618,"2246, 5295, 2248, 2254, 2255, 2549"]
["KEGG Pathways","hsa00051","Fructose and mannose metabolism",0.012950810015439415,0.1582737761949578,36.0,7.0,84030.91666666667,"3098, 3101, 5208, 5209, 5210, 5214, 80201"]
["KEGG Pathways","hsa04320","Dorso-ventral axis formation",0.013056240592164935,0.1582737761949578,24.0,7.0,178246.45833333334,"1956, 2113, 2114, 2120, 6655, 56776, 143689"]
["Reactome","R-HSA-2219528","PI3K/AKT Signaling in Cancer",0.013585592925231146,0.3447576202839085,90.0,17.0,199935.01111111112,"2246, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 5155, 5159, 8503, 9965"]
["Reactome","R-HSA-1181150","Signaling by NODAL",0.013590445140024117,0.3447576202839085,19.0,5.0,141897.05263157896,"4088, 4838, 5046, 91, 2309"]
["Reactome","R-HSA-1989781","PPARA activates gene expression",0.013691322084636552,0.3447576202839085,121.0,19.0,136792.28925619836,"51586, 196, 211, 948, 2274, 3992, 4862, 7003, 7004, 7005, 9915, 10413, 10499, 23389, 26230, 27063, 27242, 29841, 57491"]
["KEGG Pathways","hsa05218","Melanoma",0.01397599254179091,0.1582737761949578,71.0,15.0,195467.15492957746,"595, 2246, 5154, 5295, 1021, 1956, 2248, 2254, 2255, 3082, 3480, 5155, 5159, 8503, 9965"]
["KEGG Pathways","hsa05144","Malaria",0.01411858660537502,0.1582737761949578,51.0,10.0,158523.74509803922,"7042, 7058, 948, 958, 975, 3082, 3553, 6383, 7057, 7060"]
["Reactome","R-HSA-3000171","Non-integrin membrane-ECM interactions",0.014266898728237224,0.3505117619369191,64.0,13.0,228317.515625,"87, 1282, 1284, 5154, 780, 1277, 3371, 3688, 3908, 3911, 5155, 6383, 7057"]
["KEGG Pathways","hsa04380","Osteoclast differentiation",0.014644897323010726,0.1582737761949578,127.0,20.0,129821.68503937007,"4792, 5295, 7042, 1435, 1540, 2274, 2353, 2355, 3553, 3726, 3937, 4688, 4790, 4982, 5602, 5608, 5879, 6772, 7186, 8503"]
["KEGG Pathways","hsa04620","Toll-like receptor signaling pathway",0.01466927681806926,0.1582737761949578,102.0,15.0,102436.33333333333,"7100, 4792, 5295, 958, 2353, 3553, 4790, 5602, 5606, 5608, 5879, 6352, 6772, 8503, 8737"]
["Reactome","R-HSA-2219530","Constitutive Signaling by Aberrant PI3K in Cancer",0.015816096762285008,0.358855930656245,65.0,14.0,237948.5076923077,"2246, 5154, 5295, 1956, 2248, 2254, 2255, 2549, 3082, 3667, 5155, 5159, 8503, 9965"]
["Reactome","R-HSA-168249","Innate Immune System",0.016016708088607102,0.358855930656245,1250.0,124.0,110355.1696,"4627, 5575, 5747, 7100, 153090, 109, 115, 598, 818, 1843, 2246, 3708, 4792, 5154, 5295, 5660, 6196, 9693, 22821, 23114, 57161, 284266, 108, 111, 284, 684, 718, 728, 815, 948, 960, 966, 976, 997, 1027, 1113, 1437, 1476, 1499, 1508, 1509, 1540, 1794, 1847, 1956, 2248, 2254, 2255, 2309, 2353, 2549, 2760, 2906, 2934, 2950, 3074, 3082, 3101, 3164, 3553, 3667, 3937, 4048, 4208, 4214, 4651, 4688, 4790, 5023, 5058, 5136, 5155, 5159, 5305, 5536, 5553, 5602, 5606, 5608, 5657, 5690, 5795, 5879, 5921, 6285, 6518, 6993, 7128, 7133, 7186, 7462, 7867, 8398, 8503, 8566, 8737, 9048, 9114, 9208, 9535, 9965, 10458, 10555, 10694, 10890, 10892, 11322, 22918, 23112, 23191, 25797, 51332, 51646, 51719, 53831, 57731, 64581, 79155, 84166, 84766, 150372, 171568, 201294, 245972"]
["Reactome","R-HSA-3000157","Laminin interactions",0.016119773819937882,0.358855930656245,33.0,8.0,140799.51515151514,"80781, 1282, 1284, 3675, 3679, 3688, 3908, 3911"]
["Reactome","R-HSA-194138","Signaling by VEGF",0.0162297861720193,0.358855930656245,336.0,46.0,161783.54464285713,"5747, 9564, 153090, 818, 1843, 2246, 3708, 5154, 5295, 5590, 8440, 9693, 22821, 284, 815, 857, 1437, 1495, 1499, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 4688, 5058, 5155, 5159, 5536, 5690, 5879, 5921, 6461, 7867, 8828, 8829, 8877, 9048, 9965, 10458, 23191, 51332, 57731"]
["Reactome","R-HSA-1474244","Extracellular matrix organization",0.01659833166772641,0.358855930656245,298.0,41.0,161377.61744966442,"80781, 87, 1282, 1284, 5154, 7042, 9509, 2, 667, 780, 960, 977, 1277, 1292, 1303, 1508, 1509, 2006, 3371, 3675, 3678, 3679, 3682, 3688, 3908, 3911, 4017, 4052, 4326, 5155, 5654, 6383, 6868, 7057, 7143, 7148, 7373, 9508, 10536, 147968, 170690"]
["KEGG Pathways","hsa04920","Adipocytokine signaling pathway",0.018032759200595123,0.1815190291659993,68.0,12.0,130391.05882352941,"32, 4792, 51422, 948, 3667, 4790, 5602, 6794, 7133, 7186, 10645, 126129"]
["Reactome","R-HSA-114608","Platelet degranulation ",0.01915638495004097,0.3900884331473856,124.0,18.0,156702.16129032258,"87, 5099, 81, 928, 5154, 5660, 7042, 7123, 9948, 2, 948, 3082, 3699, 3700, 5155, 7057, 7078, 51097"]
["Reactome","R-HSA-1266695","Interleukin-7 signaling",0.020151245892707274,0.3900884331473856,27.0,5.0,177102.66666666666,"5295, 6776, 3082, 6777, 8503"]
["Reactome","R-HSA-168142","Toll Like Receptor 10 (TLR10) Cascade",0.02056895530934411,0.3900884331473856,84.0,14.0,141850.9880952381,"7100, 4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-168176","Toll Like Receptor 5 (TLR5) Cascade",0.02056895530934411,0.3900884331473856,84.0,14.0,141850.9880952381,"7100, 4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-975871","MyD88 cascade initiated on plasma membrane",0.02056895530934411,0.3900884331473856,84.0,14.0,141850.9880952381,"7100, 4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-5675482","Regulation of necroptotic cell death",0.021083703677873822,0.39295661509968277,18.0,4.0,70134.11111111111,"356, 7186, 8737, 8795"]
["Reactome","R-HSA-1226099","Signaling by FGFR in disease",0.02173038675061438,0.3958744116723268,63.0,11.0,131391.60317460317,"2246, 5295, 6776, 1523, 2248, 2254, 2255, 2549, 6772, 6777, 9208"]
["Reactome","R-HSA-933542","TRAF6 mediated NF-kB activation",0.021972677798649035,0.3958744116723268,25.0,5.0,89898.96,"4792, 4214, 4790, 6285, 7186"]
["Reactome","R-HSA-2691230","Signaling by NOTCH1 HD Domain Mutants in Cancer",0.023473608364315345,0.40927372002943363,15.0,4.0,126349.66666666667,"182, 54492, 28514, 6868"]
["Reactome","R-HSA-2691232","Constitutive Signaling by NOTCH1 HD Domain Mutants",0.023473608364315345,0.40927372002943363,15.0,4.0,126349.66666666667,"182, 54492, 28514, 6868"]
["Reactome","R-HSA-8875878","MET promotes cell motility",0.023889739356105732,0.4099175911738142,44.0,10.0,192170.13636363635,"64759, 5747, 1277, 2549, 3082, 3675, 3688, 3908, 3911, 5879"]
["Reactome","R-HSA-4420097","VEGFA-VEGFR2 Pathway",0.024403555958036182,0.4102182604746316,328.0,44.0,159017.8536585366,"5747, 9564, 153090, 818, 1843, 2246, 3708, 5154, 5295, 5590, 8440, 9693, 22821, 284, 815, 857, 1437, 1495, 1499, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 4688, 5058, 5155, 5159, 5536, 5690, 5879, 5921, 6461, 7867, 8877, 9048, 9965, 10458, 23191, 51332, 57731"]
["Reactome","R-HSA-157118","Signaling by NOTCH",0.026602540191911852,0.42921411861875686,111.0,18.0,179373.0990990991,"182, 9734, 9612, 54492, 55534, 595, 3091, 23493, 28514, 488, 489, 1840, 6487, 6868, 7090, 9759, 23112, 26508"]
["KEGG Pathways","hsa04270","Vascular smooth muscle contraction",0.0274226859384871,0.25475225743754754,114.0,20.0,222220.91228070174,"4638, 109, 115, 800, 1909, 3708, 5500, 59, 108, 111, 779, 2768, 3779, 4629, 4637, 5739, 8398, 9138, 10335, 23236"]
["Reactome","R-HSA-5213460","RIPK1-mediated regulated necrosis",0.027872237380918787,0.4337512189062965,20.0,4.0,65197.15,"356, 7186, 8737, 8795"]
["Reactome","R-HSA-5218859","Regulated Necrosis",0.027872237380918787,0.4337512189062965,20.0,4.0,65197.15,"356, 7186, 8737, 8795"]
["Reactome","R-HSA-210991","Basigin interactions",0.02830413274818124,0.4337512189062965,25.0,5.0,82432.8,"857, 3675, 3688, 8140, 9123"]
["Reactome","R-HSA-1500931","Cell-Cell communication",0.028488747957767853,0.4337512189062965,140.0,23.0,276163.90714285715,"87, 5747, 81, 5295, 8440, 54751, 55679, 667, 977, 1000, 1007, 1012, 1495, 1499, 3688, 5058, 5817, 5879, 8935, 10979, 49861, 55243, 56288"]
["KEGG Pathways","hsa05142","Chagas disease (American trypanosomiasis)",0.028581960590554116,0.25475225743754754,104.0,17.0,148024.04807692306,"4088, 4792, 5295, 7042, 356, 624, 718, 1636, 2353, 3553, 4790, 5520, 5522, 5602, 6352, 8503, 23236"]
["Reactome","R-HSA-2454202","Fc epsilon receptor (FCERI) signaling",0.030326958826629086,0.4553255901609173,370.0,48.0,148734.03783783785,"5747, 153090, 818, 1843, 2246, 3708, 4792, 5154, 5295, 9693, 22821, 284, 815, 997, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2353, 2549, 2906, 3082, 3164, 3667, 3937, 4214, 4790, 5058, 5155, 5159, 5305, 5536, 5602, 5690, 5879, 5921, 7462, 8503, 9048, 9965, 10892, 23112, 51332, 57731"]
["Reactome","R-HSA-140534","Ligand-dependent caspase activation",0.03104558059769885,0.4571421159663468,17.0,4.0,129110.35294117648,"356, 7186, 8737, 8795"]
["Reactome","R-HSA-1980143","Signaling by NOTCH1",0.03194966848074829,0.4571421159663468,73.0,13.0,192795.86301369863,"182, 9734, 9612, 54492, 55534, 3091, 23493, 28514, 1840, 6868, 7090, 9759, 26508"]
["Reactome","R-HSA-177929","Signaling by EGFR",0.032120974824266964,0.4571421159663468,362.0,48.0,162694.4640883978,"8874, 5575, 5747, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 9693, 22821, 26018, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 5136, 5155, 5159, 5305, 5536, 5690, 5782, 5921, 6868, 8503, 9048, 9146, 9965, 23112, 51332, 57731"]
["Reactome","R-HSA-76005","Response to elevated platelet cytosolic Ca2+",0.03250142207135874,0.4571421159663468,129.0,18.0,155639.86821705426,"87, 5099, 81, 928, 5154, 5660, 7042, 7123, 9948, 2, 948, 3082, 3699, 3700, 5155, 7057, 7078, 51097"]
["Reactome","R-HSA-163615","PKA activation",0.032562389388907216,0.4571421159663468,18.0,5.0,172361.16666666666,"5575, 109, 115, 108, 111"]
["Reactome","R-HSA-164378","PKA activation in glucagon signalling",0.033420078715253265,0.4631680139895998,17.0,5.0,184763.88235294117,"5575, 109, 115, 108, 111"]
["Reactome","R-HSA-1855204","Synthesis of IP3 and IP4 in the cytosol",0.03456996606320475,0.4730396622066371,27.0,6.0,151529.62962962964,"3705, 3707, 23007, 5333, 23236, 51196"]
["KEGG Pathways","hsa04912","GnRH signaling pathway",0.037430725509545404,0.2879583505149121,99.0,16.0,167782.88888888888,"109, 115, 818, 3708, 108, 111, 779, 815, 1956, 4214, 5602, 5606, 5608, 6655, 8398, 23236"]
["Reactome","R-HSA-73887","Death Receptor Signalling",0.03745274313745981,0.5060801916449257,50.0,8.0,93095.78,"356, 1540, 6868, 7128, 7186, 8737, 8795, 9099"]
["Reactome","R-HSA-1170546","Prolactin receptor signaling",0.038568560011592076,0.5078540858730086,16.0,4.0,124781.1875,"5618, 6776, 6777, 25970"]
["Reactome","R-HSA-1483249","Inositol phosphate metabolism",0.038733242081018096,0.5078540858730086,46.0,9.0,162439.80434782608,"3632, 3705, 3707, 23007, 5333, 11163, 23236, 51196, 117283"]
["Reactome","R-HSA-2032785","YAP1- and WWTR1 (TAZ)-stimulated gene expression",0.038993421949546456,0.5078540858730086,29.0,7.0,200116.72413793104,"28996, 4878, 7003, 7004, 7005, 10413, 10499"]
["KEGG Pathways","hsa05214","Glioma",0.04102916495375932,0.2879583505149121,64.0,12.0,137306.953125,"595, 818, 5154, 5295, 815, 1021, 1956, 3480, 5155, 5159, 6655, 8503"]
["Reactome","R-HSA-416572","Sema4D induced cell migration and growth-cone collapse",0.04170936465309579,0.5333006062197947,24.0,5.0,163188.66666666666,"4627, 4629, 4637, 5364, 5879"]
["KEGG Pathways","hsa05120","Epithelial cell signaling in Helicobacter pylori infection",0.041867965990843324,0.2879583505149121,68.0,11.0,99648.54411764706,"4792, 1956, 4790, 5058, 5602, 5879, 6352, 6868, 7082, 9114, 245972"]
["KEGG Pathways","hsa04722","Neurotrophin signaling pathway",0.04188591368359207,0.2879583505149121,126.0,20.0,146863.31746031746,"818, 4792, 5295, 6196, 6272, 356, 627, 815, 2309, 2549, 3667, 4214, 4790, 5602, 5879, 6655, 8503, 10603, 10971, 25970"]
["Reactome","R-HSA-445717","Aquaporin-mediated transport",0.04193390520692188,0.5333006062197947,52.0,9.0,115106.80769230769,"5575, 358, 109, 115, 108, 111, 362, 22841, 59345"]
["KEGG Pathways","hsa05211","Renal cell carcinoma",0.042082100786319826,0.2879583505149121,69.0,13.0,161605.5072463768,"2034, 3091, 5295, 7042, 2113, 2549, 3082, 5058, 5155, 5879, 6655, 8503, 9915"]
["Reactome","R-HSA-6783783","Interleukin-10 signaling",0.043082980774772926,0.5340498825263964,48.0,7.0,66780.3125,"1435, 1437, 3553, 3596, 6352, 6363, 7133"]
["Reactome","R-HSA-111465","Apoptotic cleavage of cellular proteins",0.04347492105672793,0.5340498825263964,38.0,8.0,188179.97368421053,"5747, 1499, 2934, 4000, 6304, 7082, 7431, 8428"]
["KEGG Pathways","hsa04360","Axon guidance",0.04354492129737695,0.2879583505149121,129.0,22.0,362390.4418604651,"5747, 6586, 8440, 9353, 10509, 23654, 1969, 2043, 2047, 3688, 5058, 5364, 5879, 5921, 5998, 6387, 8829, 10500, 54437, 54910, 64221, 223117"]
["Reactome","R-HSA-5654695","PI-3K cascade:FGFR2",0.04548097402207907,0.5495190100966506,23.0,6.0,222689.30434782608,"2246, 5295, 2248, 2254, 2255, 2549"]
["Reactome","R-HSA-2172127","DAP12 interactions",0.0457508889072142,0.5495190100966506,363.0,46.0,149556.74931129476,"5575, 5747, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 9693, 22821, 284266, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 3937, 5136, 5155, 5159, 5305, 5536, 5690, 5879, 5921, 8503, 9048, 9965, 23112, 51332, 57731"]
["KEGG Pathways","hsa00052","Galactose metabolism",0.045799418560137514,0.29340252515088094,27.0,5.0,78333.07407407407,"3098, 2595, 3101, 5214, 80201"]
["Reactome","R-HSA-5654720","PI-3K cascade:FGFR4",0.048204388646148566,0.5660471521875995,20.0,5.0,180008.75,"2246, 5295, 2254, 2549, 9965"]
["Reactome","R-HSA-2424491","DAP12 signaling",0.04869785860633372,0.5660471521875995,352.0,45.0,152431.44886363635,"5575, 5747, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 9693, 22821, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 3937, 5136, 5155, 5159, 5305, 5536, 5690, 5879, 5921, 8503, 9048, 9965, 23112, 51332, 57731"]
["Reactome","R-HSA-111931","PKA-mediated phosphorylation of CREB",0.050051703910668426,0.5695591523246445,19.0,5.0,176104.1052631579,"5575, 109, 115, 108, 111"]
["Reactome","R-HSA-166058","MyD88:Mal cascade initiated on plasma membrane",0.05058064627489905,0.5695591523246445,94.0,14.0,143369.4255319149,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-168188","Toll Like Receptor TLR6:TLR2 Cascade",0.05058064627489905,0.5695591523246445,94.0,14.0,143369.4255319149,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-3295583","TRP channels",0.051203536152437994,0.5706290987709842,28.0,6.0,150529.5,"4308, 7442, 8737, 8989, 54795, 80036"]
["Reactome","R-HSA-6806834","Signaling by MET",0.05269219431512602,0.579529624578931,82.0,14.0,168338.84146341463,"64759, 5747, 5295, 26018, 1277, 2549, 3082, 3675, 3688, 3908, 3911, 5795, 5879, 9146"]
["Reactome","R-HSA-432040","Vasopressin regulates renal water homeostasis via Aquaporins",0.05352146992120787,0.579529624578931,43.0,8.0,128728.41860465116,"5575, 358, 109, 115, 108, 111, 22841, 59345"]
["Reactome","R-HSA-1810476","RIP-mediated NFkB activation via ZBP1",0.05361051106188075,0.579529624578931,21.0,4.0,88423.76190476191,"4792, 4790, 6285, 8737"]
["KEGG Pathways","hsa04973","Carbohydrate digestion and absorption",0.05616378168891997,0.3488962195826847,42.0,8.0,184323.52380952382,"3098, 5295, 477, 486, 3101, 6518, 8503, 80201"]
["Reactome","R-HSA-5663202","Diseases of signal transduction",0.057684602247556574,0.5863686352342573,367.0,45.0,149113.9782016349,"23164, 182, 1488, 9734, 4088, 9612, 54492, 55534, 153090, 2246, 5154, 5295, 6776, 22821, 22906, 23493, 28514, 1027, 1499, 1523, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 4000, 5155, 5159, 5690, 5921, 6772, 6777, 6868, 8503, 9208, 9444, 9759, 9965, 23499, 26508, 64220"]
["Reactome","R-HSA-5357956","TNFR1-induced NFkappaB signaling pathway",0.058713256562154426,0.5863686352342573,30.0,5.0,93243.56666666667,"1540, 7128, 7186, 8737, 9099"]
["Reactome","R-HSA-140877","Formation of Fibrin Clot (Clotting Cascade)",0.05882103372428833,0.5863686352342573,38.0,6.0,134702.1052631579,"2, 2811, 2815, 5104, 5624, 5657"]
["Reactome","R-HSA-5083635","Defective B3GALTL causes Peters-plus syndrome (PpS)",0.05910547595950606,0.5863686352342573,35.0,9.0,293522.65714285715,"7058, 9509, 7057, 9508, 10417, 54437, 79875, 170690, 170691"]
["Reactome","R-HSA-446728","Cell junction organization",0.059243035960185514,0.5863686352342573,91.0,15.0,304006.37362637365,"87, 54751, 55679, 667, 977, 1000, 1007, 1012, 1495, 1499, 3688, 5817, 10979, 49861, 56288"]
["Reactome","R-HSA-212718","EGFR interacts with phospholipase C-gamma",0.06019643616430001,0.5863686352342573,35.0,8.0,203024.6,"5575, 109, 115, 3708, 108, 111, 1956, 5136"]
["Reactome","R-HSA-2644602","Signaling by NOTCH1 PEST Domain Mutants in Cancer",0.060209915366329844,0.5863686352342573,58.0,10.0,157321.0344827586,"182, 9734, 9612, 54492, 55534, 23493, 28514, 6868, 9759, 26508"]
["Reactome","R-HSA-2644603","Signaling by NOTCH1 in Cancer",0.060209915366329844,0.5863686352342573,58.0,10.0,157321.0344827586,"182, 9734, 9612, 54492, 55534, 23493, 28514, 6868, 9759, 26508"]
["Reactome","R-HSA-2644606","Constitutive Signaling by NOTCH1 PEST Domain Mutants",0.060209915366329844,0.5863686352342573,58.0,10.0,157321.0344827586,"182, 9734, 9612, 54492, 55534, 23493, 28514, 6868, 9759, 26508"]
["Reactome","R-HSA-2894858","Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer",0.060209915366329844,0.5863686352342573,58.0,10.0,157321.0344827586,"182, 9734, 9612, 54492, 55534, 23493, 28514, 6868, 9759, 26508"]
["Reactome","R-HSA-2894862","Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants",0.060209915366329844,0.5863686352342573,58.0,10.0,157321.0344827586,"182, 9734, 9612, 54492, 55534, 23493, 28514, 6868, 9759, 26508"]
["KEGG Pathways","hsa05100","Bacterial invasion of epithelial cells",0.06050563005521884,0.35509791245319317,70.0,12.0,184612.12857142856,"5747, 9564, 858, 5295, 857, 1495, 1499, 2549, 3678, 3688, 5879, 8503"]
["KEGG Pathways","hsa04260","Cardiac muscle contraction",0.060626472857862254,0.35509791245319317,73.0,11.0,131726.02739726027,"6546, 477, 486, 488, 779, 781, 782, 4634, 7171, 9254, 84701"]
["Reactome","R-HSA-5357905","Regulation of TNFR1 signaling",0.061827420793086736,0.593245417118889,33.0,5.0,66751.87878787878,"1540, 7128, 7186, 8737, 9099"]
["Reactome","R-HSA-2682334","EPH-Ephrin signaling",0.06248037715044304,0.593245417118889,94.0,15.0,245173.06382978722,"8874, 4627, 5747, 8440, 1969, 2043, 2047, 4629, 4637, 5058, 5879, 5921, 6383, 6461, 10627"]
["Reactome","R-HSA-6811558","PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",0.06256242141679311,0.593245417118889,87.0,15.0,201594.8735632184,"2246, 5154, 5295, 1956, 2248, 2254, 2255, 2549, 3082, 3667, 5155, 5159, 5305, 8503, 9965"]
["KEGG Pathways","hsa05215","Prostate cancer",0.06357672489148077,0.35820164330736715,89.0,15.0,161154.0,"595, 4792, 5154, 5295, 1027, 1499, 1956, 2950, 3480, 4790, 5155, 5159, 6655, 8503, 9586"]
["Reactome","R-HSA-168179","Toll Like Receptor TLR1:TLR2 Cascade",0.06373656584662704,0.593958859312102,97.0,14.0,140890.82474226804,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-181438","Toll Like Receptor 2 (TLR2) Cascade",0.06373656584662704,0.593958859312102,97.0,14.0,140890.82474226804,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-5654219","Phospholipase C-mediated cascade: FGFR1",0.0652972199089043,0.6033016642865431,16.0,4.0,147777.75,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-418360","Platelet calcium homeostasis",0.06700184461873038,0.613805034176674,29.0,6.0,174883.06896551725,"3708, 6546, 488, 489, 5023, 100616453"]
["KEGG Pathways","hsa05416","Viral myocarditis",0.06714083153741603,0.35820164330736715,68.0,10.0,139741.57352941178,"4627, 595, 6445, 857, 958, 3908, 4621, 4629, 5879, 6442"]
["KEGG Pathways","hsa04144","Endocytosis",0.06793039226712591,0.35820164330736715,201.0,27.0,146092.3432835821,"4088, 10938, 858, 4092, 5590, 7042, 9922, 30846, 116984, 153, 154, 857, 1956, 3480, 8853, 9146, 11059, 11267, 22841, 23327, 23362, 51100, 56288, 64744, 89853, 116987, 131890"]
["KEGG Pathways","hsa04530","Tight junction",0.06814567848286497,0.35820164330736715,132.0,20.0,166270.31818181818,"87, 4627, 81, 5590, 23136, 1495, 1499, 4621, 4629, 5520, 5522, 7082, 8777, 9223, 10627, 22800, 29895, 49861, 51776, 56288"]
["Reactome","R-HSA-190242","FGFR1 ligand binding and activation",0.07180367362472334,0.6362276326911962,16.0,4.0,151875.0625,"2246, 2248, 2254, 2255"]
["KEGG Pathways","hsa05212","Pancreatic cancer",0.07286417923779023,0.37342891859367494,70.0,12.0,150152.3142857143,"4088, 595, 598, 5295, 7042, 1021, 1956, 4790, 5602, 5879, 6772, 8503"]
["Reactome","R-HSA-5654736","Signaling by FGFR1",0.07344166870562545,0.6386855745647371,50.0,9.0,208550.0,"2246, 5295, 23768, 2248, 2254, 2255, 2549, 23769, 53834"]
["KEGG Pathways","hsa04330","Notch signaling pathway",0.07506803480574033,0.37356523613809856,47.0,7.0,96358.87234042553,"182, 1488, 9612, 55534, 28514, 1840, 6868"]
["Reactome","R-HSA-8848021","Signaling by PTK6",0.07641355376696923,0.6386855745647371,67.0,11.0,246708.1343283582,"2034, 9564, 153090, 595, 2908, 3091, 22821, 1027, 1956, 5879, 5921"]
["Reactome","R-HSA-109704","PI3K Cascade",0.07684852899887744,0.6386855745647371,79.0,12.0,137692.7088607595,"2246, 5295, 51422, 57521, 2248, 2254, 2255, 2549, 3667, 6794, 9965, 51719"]
["Reactome","R-HSA-2871796","FCERI mediated MAPK activation",0.07685455706296344,0.6386855745647371,266.0,34.0,154302.95864661655,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2353, 2906, 3082, 3667, 3937, 4214, 5058, 5155, 5159, 5536, 5602, 5690, 5879, 5921, 9048, 9965, 51332, 57731"]
["KEGG Pathways","hsa04640","Hematopoietic cell lineage",0.07704438694064075,0.37356523613809856,85.0,12.0,104771.1294117647,"928, 947, 948, 960, 966, 1435, 1437, 2811, 2815, 3553, 3675, 3678"]
["Reactome","R-HSA-1433557","Signaling by SCF-KIT",0.07723447795449682,0.6386855745647371,334.0,41.0,148349.2125748503,"5747, 153090, 818, 1843, 2246, 5154, 5295, 6776, 9693, 22821, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 5155, 5159, 5305, 5536, 5690, 5879, 5921, 6772, 6777, 8503, 9048, 9965, 10076, 23112, 51332, 57731"]
["Reactome","R-HSA-400685","Sema4D in semaphorin signaling",0.07829841525446354,0.6386855745647371,27.0,5.0,155349.03703703705,"4627, 4629, 4637, 5364, 5879"]
["KEGG Pathways","hsa04070","Phosphatidylinositol signaling system",0.0783575861167719,0.37356523613809856,77.0,13.0,165585.8051948052,"3632, 1607, 3705, 3707, 3708, 5295, 8527, 8871, 5305, 5333, 8503, 23236, 51196"]
["Reactome","R-HSA-1257604","PIP3 activates AKT signaling",0.07858018632480114,0.6386855745647371,125.0,19.0,175371.888,"2246, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 5155, 5159, 5305, 8503, 9965, 23112"]
["Reactome","R-HSA-419037","NCAM1 interactions",0.08013363989913581,0.6464512293355658,43.0,9.0,210586.37209302327,"1282, 1284, 8912, 779, 782, 1292, 7903, 8911, 9048"]
["Reactome","R-HSA-2730905","Role of LAT2/NTAL/LAB on calcium mobilization",0.08123288159360688,0.6479449383326926,134.0,20.0,171994.41044776118,"2246, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 5155, 5159, 5305, 7462, 8503, 9965, 23112"]
["KEGG Pathways","hsa04974","Protein digestion and absorption",0.08174087624046303,0.376214936816687,80.0,13.0,144484.375,"80781, 1282, 1284, 6546, 477, 486, 1277, 1292, 1303, 1803, 2006, 7373, 340024"]
["KEGG Pathways","hsa04930","Type II diabetes mellitus",0.08258376661829715,0.376214936816687,48.0,9.0,172343.22916666666,"3098, 5295, 5590, 3101, 3667, 5602, 8503, 80201, 389692"]
["Reactome","R-HSA-2022090","Assembly of collagen fibrils and other multimeric structures",0.0848348239544639,0.6601685290048475,64.0,11.0,163461.609375,"80781, 1282, 1284, 667, 977, 1277, 1292, 1303, 1508, 4017, 7373"]
["Reactome","R-HSA-975138","TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",0.08779156853532644,0.6601685290048475,91.0,13.0,143377.63736263735,"4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-1266738","Developmental Biology",0.08853949243536494,0.6601685290048475,1075.0,108.0,156032.74325581396,"8874, 1879, 4627, 1282, 1284, 2034, 4088, 4209, 5747, 7026, 8912, 9612, 27086, 51586, 153090, 818, 1843, 2246, 3199, 3213, 4838, 5046, 5154, 5295, 6196, 6477, 6586, 8440, 9353, 9693, 22821, 23114, 23129, 84962, 91, 214, 284, 286, 288, 779, 782, 815, 948, 1000, 1292, 1437, 1495, 1499, 1847, 1956, 1969, 2043, 2047, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3667, 3678, 3688, 3713, 3892, 4208, 4629, 4637, 4651, 4790, 5058, 5155, 5159, 5306, 5346, 5364, 5536, 5608, 5690, 5879, 5914, 5921, 6383, 6461, 6655, 6925, 6929, 7204, 7903, 8503, 8828, 8829, 8911, 9043, 9048, 9935, 9965, 10499, 10627, 23254, 23389, 51332, 55740, 57731, 64221, 112802, 353137, 389692"]
["Reactome","R-HSA-375165","NCAM signaling for neurite out-growth",0.08868449563735997,0.6601685290048475,280.0,36.0,157991.60357142857,"1282, 1284, 5747, 8912, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 779, 782, 815, 1292, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 7903, 8911, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-5173214","O-glycosylation of TSR domain-containing proteins",0.08916558898514781,0.6601685290048475,37.0,9.0,289827.5945945946,"7058, 9509, 7057, 9508, 10417, 54437, 79875, 170690, 170691"]
["Reactome","R-HSA-422475","Axon guidance",0.09019614161859242,0.6601685290048475,564.0,72.0,206948.81028368796,"8874, 4627, 1282, 1284, 5747, 8912, 153090, 818, 1843, 2246, 5154, 5295, 6196, 6477, 6586, 8440, 9353, 9693, 22821, 23114, 23129, 214, 284, 286, 288, 779, 782, 815, 1292, 1437, 1847, 1956, 1969, 2043, 2047, 2248, 2254, 2255, 2549, 2906, 3082, 3667, 3678, 3688, 4629, 4637, 4651, 5058, 5155, 5159, 5306, 5364, 5536, 5690, 5879, 5921, 6383, 6461, 6655, 7204, 7903, 8503, 8828, 8829, 8911, 9048, 9965, 10627, 51332, 55740, 57731, 64221"]
["Reactome","R-HSA-3000170","Syndecan interactions",0.09056895295027986,0.6601685290048475,29.0,6.0,152606.44827586206,"87, 1277, 3371, 3688, 6383, 7057"]
["Reactome","R-HSA-5625740","RHO GTPases activate PKNs",0.09061760427413748,0.6601685290048475,88.0,8.0,69027.95454545454,"4627, 5500, 4629, 4637, 5879, 10499, 10971, 23081"]
["Reactome","R-HSA-170670","Adenylate cyclase inhibitory pathway",0.09068359584076445,0.6601685290048475,15.0,4.0,208425.2,"109, 115, 108, 111"]
["Reactome","R-HSA-997269","Inhibition of adenylate cyclase pathway",0.09068359584076445,0.6601685290048475,15.0,4.0,208425.2,"109, 115, 108, 111"]
["Reactome","R-HSA-5576891","Cardiac conduction",0.09120153307247891,0.6601685290048475,141.0,21.0,183824.79432624113,"818, 1760, 3708, 6546, 28996, 477, 486, 488, 489, 779, 781, 782, 815, 845, 3777, 4878, 6588, 9254, 30818, 51305, 100616453"]
["Reactome","R-HSA-111933","Calmodulin induced events",0.09190007510313888,0.6601685290048475,27.0,6.0,190293.33333333334,"5575, 109, 115, 108, 111, 5136"]
["Reactome","R-HSA-111997","CaM pathway",0.09190007510313888,0.6601685290048475,27.0,6.0,190293.33333333334,"5575, 109, 115, 108, 111, 5136"]
["Reactome","R-HSA-5627117","RHO GTPases Activate ROCKs",0.09334220786588937,0.663835044098858,17.0,4.0,228409.41176470587,"4627, 5500, 4629, 4637"]
["Reactome","R-HSA-8874081","MET activates PTK2 signaling",0.09479192794508776,0.6679942261280594,33.0,7.0,188409.45454545456,"5747, 1277, 3082, 3675, 3688, 3908, 3911"]
["Reactome","R-HSA-198203","PI3K/AKT activation",0.09651571730251893,0.6679942261280594,128.0,19.0,173956.3984375,"2246, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 5155, 5159, 5305, 8503, 9965, 23112"]
["Reactome","R-HSA-180292","GAB1 signalosome",0.09720296003330567,0.6679942261280594,128.0,19.0,173680.9453125,"2246, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 5155, 5159, 5305, 8503, 9965, 23112"]
["Reactome","R-HSA-163359","Glucagon signaling in metabolic regulation",0.09757141789778512,0.6679942261280594,33.0,6.0,128324.30303030302,"5575, 109, 115, 108, 111, 59345"]
["Reactome","R-HSA-168181","Toll Like Receptor 7/8 (TLR7/8) Cascade",0.09887056075900971,0.6679942261280594,93.0,13.0,141489.5806451613,"4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-975155","MyD88 dependent cascade initiated on endosome",0.09887056075900971,0.6679942261280594,93.0,13.0,141489.5806451613,"4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-1606322","ZBP1(DAI) mediated induction of type I IFNs",0.1028250855591955,0.6736601059969112,25.0,4.0,82491.88,"4792, 4790, 6285, 8737"]
["Reactome","R-HSA-166054","Activated TLR4 signalling",0.10491701163832223,0.675091009410871,114.0,15.0,132570.16666666666,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["KEGG Pathways","hsa04210","Apoptosis",0.10607206585462484,0.4530161145874602,87.0,12.0,113069.62068965517,"5575, 598, 4792, 5295, 356, 3553, 3556, 4790, 7186, 8503, 8737, 8795"]
["Reactome","R-HSA-1489509","DAG and IP3 signaling",0.10617574790685211,0.6788420129170247,33.0,7.0,197396.84848484848,"5575, 109, 115, 3708, 108, 111, 5136"]
["Reactome","R-HSA-3000480","Scavenging by Class A Receptors",0.10774576069941355,0.6788420129170247,21.0,4.0,167079.2380952381,"1282, 1284, 1277, 4481"]
["Reactome","R-HSA-5683057","MAPK family signaling cascades",0.10801186514498451,0.6788420129170247,288.0,36.0,156606.05555555556,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 989, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2906, 3082, 3667, 5058, 5155, 5159, 5536, 5690, 5879, 5921, 8555, 8556, 9048, 9965, 10602, 23112, 51332, 57731"]
["Reactome","R-HSA-3928663","EPHA-mediated growth cone collapse",0.11014895721788598,0.6840274234993214,34.0,7.0,433008.20588235295,"4627, 5747, 1969, 2043, 4629, 4637, 6461"]
["Reactome","R-HSA-418594","G alpha (i) signalling events",0.11016920424720522,0.6840274234993214,241.0,28.0,141290.8174273859,"109, 115, 623, 2852, 5999, 108, 111, 152, 624, 718, 728, 1236, 1325, 1814, 1902, 5368, 5996, 6000, 6003, 6004, 6352, 6363, 6387, 8490, 8787, 10636, 59345, 339403"]
["Reactome","R-HSA-196849","Metabolism of water-soluble vitamins and cofactors",0.11459814700277134,0.6840274234993214,121.0,16.0,127906.31404958677,"32, 4337, 60490, 4363, 5091, 5740, 8029, 8566, 9962, 10840, 23057, 23475, 25902, 60496, 64087, 81693"]
["Reactome","R-HSA-390522","Striated Muscle Contraction",0.11536876947146885,0.6840274234993214,36.0,5.0,138257.63888888888,"1674, 4621, 4634, 7171, 7431"]
["Reactome","R-HSA-2586552","Signaling by Leptin",0.11609540598236939,0.6840274234993214,251.0,31.0,151656.390438247,"5747, 153090, 818, 1843, 2246, 5154, 6776, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6777, 9048, 9965, 25970, 51332, 57731"]
["Reactome","R-HSA-376176","Signaling by Robo receptor",0.11821045157021197,0.6840274234993214,31.0,7.0,348483.93548387097,"8440, 9353, 5058, 5879, 6655, 55740, 64221"]
["Reactome","R-HSA-442660","Na+/Cl- dependent neurotransmitter transporters",0.11845939944930116,0.6840274234993214,19.0,4.0,153693.84210526315,"55117, 6533, 6536, 340024"]
["Reactome","R-HSA-2122948","Activated NOTCH1 Transmits Signal to the Nucleus",0.11941975272457583,0.6840274234993214,30.0,5.0,120439.63333333333,"182, 54492, 28514, 1840, 6868"]
["Reactome","R-HSA-5654696","Downstream signaling of activated FGFR2",0.12008429412198714,0.6840274234993214,30.0,6.0,189046.83333333334,"2246, 5295, 2248, 2254, 2255, 2549"]
["KEGG Pathways","hsa04540","Gap junction",0.12350664604754462,0.5125864447809533,89.0,15.0,203247.59550561797,"109, 115, 3708, 5154, 108, 111, 153, 1902, 1956, 3357, 5155, 5159, 6655, 7082, 23236"]
["KEGG Pathways","hsa04012","ErbB signaling pathway",0.12502108409291546,0.5125864447809533,87.0,14.0,184897.83908045976,"5747, 818, 5295, 6776, 8440, 815, 1027, 1956, 2549, 5058, 5602, 6655, 6777, 8503"]
["Reactome","R-HSA-216083","Integrin cell surface interactions",0.12571728244314068,0.6840274234993214,87.0,13.0,123549.4367816092,"80781, 1282, 1284, 960, 1277, 1292, 3371, 3675, 3678, 3679, 3682, 3688, 7057"]
["Reactome","R-HSA-2173788","Downregulation of TGF-beta receptor signaling",0.1266458239420415,0.6840274234993214,26.0,5.0,152474.38461538462,"4088, 56937, 4092, 5500, 23327"]
["Reactome","R-HSA-451927","Interleukin-2 signaling",0.1282287555223649,0.6840274234993214,260.0,32.0,154655.20769230768,"5747, 153090, 818, 1843, 2246, 5154, 5295, 6776, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6777, 8503, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-400253","Circadian Clock",0.12918083652328596,0.6840274234993214,69.0,11.0,181015.5652173913,"4209, 2908, 3091, 5500, 8553, 28999, 4208, 4862, 10499, 64784, 150094"]
["Reactome","R-HSA-199418","Negative regulation of the PI3K/AKT network",0.13063829907636548,0.6840274234993214,94.0,15.0,200561.2340425532,"2246, 5154, 5295, 1956, 2248, 2254, 2255, 2549, 3082, 3667, 5155, 5159, 5305, 8503, 9965"]
["Reactome","R-HSA-187037","NGF signalling via TRKA from the plasma membrane",0.13435902916778114,0.6840274234993214,384.0,46.0,154171.97916666666,"5575, 5747, 153090, 109, 115, 818, 1843, 2246, 3708, 5154, 5295, 6196, 9693, 22821, 108, 111, 284, 815, 1027, 1437, 1847, 1956, 2248, 2254, 2255, 2309, 2549, 2906, 3082, 3164, 3667, 4208, 5136, 5155, 5159, 5305, 5536, 5690, 5921, 7867, 8503, 9048, 9965, 23112, 51332, 57731"]
["KEGG Pathways","hsa05323","Rheumatoid arthritis",0.13448464362751053,0.5273371875366437,89.0,11.0,100111.2808988764,"7042, 284, 1435, 1437, 1493, 2353, 3553, 6352, 6387, 9114, 245972"]
["Reactome","R-HSA-75153","Apoptotic execution  phase",0.13639759741000165,0.6840274234993214,52.0,8.0,150705.53846153847,"5747, 1499, 2934, 4000, 6304, 7082, 7431, 8428"]
["Reactome","R-HSA-75893","TNF signaling",0.13678657126998145,0.6840274234993214,43.0,6.0,93214.02325581395,"1540, 6868, 7128, 7186, 8737, 9099"]
["Reactome","R-HSA-211976","Endogenous sterols",0.13798002952654914,0.6840274234993214,27.0,5.0,128624.81481481482,"196, 1545, 5740, 9915, 10499"]
["KEGG Pathways","hsa04623","Cytosolic DNA-sensing pathway",0.14021411675480663,0.5322943321247289,55.0,6.0,50032.87272727273,"4792, 3553, 4790, 6352, 8737, 171568"]
["Reactome","R-HSA-6798695","Neutrophil degranulation",0.1404868560712803,0.6840274234993214,473.0,43.0,84516.6934460888,"5660, 23114, 684, 718, 728, 948, 960, 966, 976, 1476, 1508, 1509, 1794, 2760, 2934, 2950, 3074, 3101, 4048, 4790, 5023, 5553, 5657, 5795, 5879, 6518, 6993, 7133, 8566, 9535, 10555, 10694, 10890, 11322, 22918, 23191, 25797, 51646, 51719, 53831, 84766, 150372, 201294"]
["Reactome","R-HSA-5654716","Downstream signaling of activated FGFR4",0.14153009839229155,0.6840274234993214,27.0,5.0,153693.55555555556,"2246, 5295, 2254, 2549, 9965"]
["Reactome","R-HSA-76009","Platelet Aggregation (Plug Formation)",0.14190192641834726,0.6840274234993214,37.0,6.0,122577.37837837837,"5747, 9564, 152, 1277, 2811, 2815"]
["Reactome","R-HSA-111996","Ca-dependent events",0.1433717805004952,0.6840274234993214,29.0,6.0,246104.89655172414,"5575, 109, 115, 108, 111, 5136"]
["KEGG Pathways","hsa00770","Pantothenate and CoA biosynthesis",0.14387340274327454,0.5362554102249323,16.0,3.0,105268.3125,"60490, 586, 51733"]
["Reactome","R-HSA-418457","cGMP effects",0.14450715495338273,0.6840274234993214,18.0,5.0,339456.77777777775,"3708, 3779, 5136, 5138, 10335"]
["Reactome","R-HSA-167021","PLC-gamma1 signalling",0.14529326595779896,0.6840274234993214,35.0,7.0,195201.62857142856,"5575, 109, 115, 3708, 108, 111, 5136"]
["Reactome","R-HSA-936837","Ion transport by P-type ATPases",0.14557941306145503,0.6840274234993214,56.0,9.0,136650.9107142857,"818, 477, 486, 488, 489, 815, 5205, 6588, 57194"]
["Reactome","R-HSA-983712","Ion channel transport",0.1466202758894452,0.6840274234993214,211.0,27.0,143840.57819905214,"818, 477, 486, 488, 489, 815, 845, 2569, 2570, 4308, 5205, 6588, 7442, 8737, 8989, 9114, 11059, 23327, 23678, 53373, 54795, 57194, 80036, 80727, 121601, 219931, 245972"]
["KEGG Pathways","hsa04520","Adherens junction",0.14771254545713727,0.5407334253341632,73.0,13.0,218789.90410958903,"87, 4088, 81, 1495, 1499, 1956, 3480, 4008, 5795, 5879, 7082, 10458, 56288"]
["Reactome","R-HSA-2173782","Binding and Uptake of Ligands by Scavenger Receptors",0.1491933445679378,0.6840274234993214,43.0,6.0,121390.55813953489,"1282, 1284, 948, 1277, 4481, 23166"]
["Reactome","R-HSA-5654688","SHC-mediated cascade:FGFR1",0.14943009933741014,0.6840274234993214,21.0,4.0,130986.09523809524,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-5654710","PI-3K cascade:FGFR3",0.15319408462835374,0.6840274234993214,18.0,4.0,194458.66666666666,"2246, 5295, 2254, 2549"]
["Reactome","R-HSA-3296482","Defects in vitamin and cofactor metabolism",0.15366316049667986,0.6840274234993214,17.0,4.0,198931.70588235295,"5091, 8029, 64087, 81693"]
["Reactome","R-HSA-70326","Glucose metabolism",0.15767822286627656,0.6840274234993214,80.0,10.0,132742.9375,"3098, 2632, 3101, 5091, 5208, 5209, 5210, 5214, 5224, 5257"]
["Reactome","R-HSA-2428924","IGF1R signaling cascade",0.15856411837930343,0.6840274234993214,296.0,35.0,149491.7939189189,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3480, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9965, 51332, 51719, 57731"]
["Reactome","R-HSA-2428928","IRS-related events triggered by IGF1R",0.15856411837930343,0.6840274234993214,296.0,35.0,149491.7939189189,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3480, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9965, 51332, 51719, 57731"]
["Reactome","R-HSA-168138","Toll Like Receptor 9 (TLR9) Cascade",0.16037293494187313,0.6840274234993214,97.0,13.0,144800.07216494845,"4792, 6196, 57161, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 79155"]
["Reactome","R-HSA-8849471","PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases",0.16051939058065284,0.6840274234993214,27.0,5.0,168589.44444444444,"9564, 153090, 22821, 5879, 5921"]
["KEGG Pathways","hsa04972","Pancreatic secretion",0.1613061997603584,0.5801363324714645,99.0,14.0,170489.15151515152,"109, 115, 3708, 108, 111, 477, 486, 488, 489, 886, 5879, 8398, 23236, 219931"]
["Reactome","R-HSA-2404192","Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)",0.16287080241463742,0.685949546786771,297.0,35.0,149159.25252525252,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3480, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9965, 51332, 51719, 57731"]
["Reactome","R-HSA-2033519","Activated point mutants of FGFR2",0.16307958697890854,0.685949546786771,17.0,4.0,212034.4705882353,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-1660662","Glycosphingolipid metabolism",0.16421186550628827,0.6866097396024924,44.0,6.0,123917.38636363637,"2581, 5660, 2760, 3074, 6609, 57488"]
["Reactome","R-HSA-1442490","Collagen degradation",0.16450686638024561,0.6866097396024924,66.0,10.0,140558.81818181818,"80781, 1282, 1284, 1277, 1292, 1303, 1508, 1509, 6868, 7373"]
["KEGG Pathways","hsa00010","Glycolysis / Gluconeogenesis",0.16666087946031924,0.5890600049890593,65.0,8.0,88035.63076923077,"220, 3098, 219, 3101, 5214, 5224, 80201, 84532"]
["Reactome","R-HSA-373753","Nephrin interactions",0.16731952230745012,0.6917462854526109,23.0,5.0,267834.7826086957,"87, 81, 5295, 8440, 55243"]
["Reactome","R-HSA-5260271","Diseases of Immune System",0.1742966530589218,0.6994459558879632,24.0,4.0,131539.91666666666,"7100, 4792, 948, 4790"]
["Reactome","R-HSA-5602358","Diseases associated with the TLR signaling cascade",0.1742966530589218,0.6994459558879632,24.0,4.0,131539.91666666666,"7100, 4792, 948, 4790"]
["Reactome","R-HSA-389957","Prefoldin mediated transfer of substrate  to CCT/TriC",0.17666492223980768,0.6994459558879632,28.0,3.0,42544.28571428572,"5201, 6950, 10694"]
["KEGG Pathways","hsa01040","Biosynthesis of unsaturated fatty acids",0.1766651270011498,0.5905815729243087,21.0,3.0,58917.142857142855,"3992, 8310, 9524"]
["KEGG Pathways","hsa04664","Fc epsilon RI signaling pathway",0.17749951884475335,0.5905815729243087,78.0,11.0,146190.62820512822,"5295, 1437, 3596, 3937, 5602, 5606, 5608, 5879, 6655, 8398, 8503"]
["Reactome","R-HSA-2122947","NOTCH1 Intracellular Domain Regulates Transcription",0.17775296412924527,0.6994459558879632,48.0,8.0,222151.16666666666,"9734, 9612, 55534, 3091, 23493, 7090, 9759, 26508"]
["Reactome","R-HSA-2022377","Metabolism of Angiotensinogen to Angiotensins",0.1778870085626094,0.6994459558879632,17.0,3.0,116912.94117647059,"1509, 1636, 84909"]
["Reactome","R-HSA-5218921","VEGFR2 mediated cell proliferation",0.18012346972064325,0.6994459558879632,256.0,31.0,155218.3515625,"5747, 153090, 818, 1843, 2246, 3708, 5154, 5590, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 8877, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-112399","IRS-mediated signalling",0.1809585576680571,0.6994459558879632,292.0,34.0,148002.59931506848,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9965, 51332, 51719, 57731"]
["Reactome","R-HSA-114604","GPVI-mediated activation cascade",0.18143989962435408,0.6994459558879632,56.0,8.0,122575.57142857143,"5295, 5590, 10630, 1277, 1437, 3937, 5879, 8503"]
["KEGG Pathways","hsa04971","Gastric acid secretion",0.18548574927768924,0.595797841017001,73.0,12.0,203410.34246575343,"4638, 109, 115, 818, 3708, 108, 111, 477, 815, 3274, 3773, 23236"]
["Reactome","R-HSA-112043","PLC beta mediated events",0.18552326679507536,0.6994459558879632,46.0,8.0,223525.47826086957,"5575, 109, 115, 3708, 108, 111, 5136, 23236"]
["KEGG Pathways","hsa05221","Acute myeloid leukemia",0.1860051796345759,0.595797841017001,57.0,9.0,152619.56140350876,"595, 861, 5295, 6776, 4790, 5914, 6655, 6777, 8503"]
["Reactome","R-HSA-512988","Interleukin-3, 5 and GM-CSF signaling",0.18932852382086626,0.6994459558879632,269.0,32.0,153145.69144981413,"5747, 153090, 818, 1843, 2246, 5154, 5295, 6776, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6777, 8503, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-1474290","Collagen formation",0.18995597861210003,0.6994459558879632,93.0,14.0,177492.60215053763,"80781, 1282, 1284, 9509, 667, 977, 1277, 1292, 1303, 1508, 4017, 7373, 9508, 10536"]
["Reactome","R-HSA-202733","Cell surface interactions at the vascular wall",0.1902285948483452,0.6994459558879632,135.0,16.0,136192.77777777778,"285, 5295, 6404, 284, 857, 960, 1277, 3675, 3678, 3688, 4072, 5624, 6383, 8140, 8795, 9123"]
["Reactome","R-HSA-3000178","ECM proteoglycans",0.19197262876152704,0.7034658023430873,76.0,12.0,165656.38157894736,"1282, 1284, 7042, 1277, 1292, 3371, 3679, 3688, 3908, 3911, 7143, 7148"]
["Reactome","R-HSA-432722","Golgi Associated Vesicle Biogenesis",0.19518336356418411,0.7073302647812787,57.0,8.0,115189.54385964913,"6272, 51429, 7164, 8301, 9026, 9698, 10618, 26258"]
["Reactome","R-HSA-5654221","Phospholipase C-mediated cascade; FGFR2",0.19599880162533892,0.7073302647812787,18.0,4.0,205946.88888888888,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-190236","Signaling by FGFR",0.19629887089212172,0.7073302647812787,88.0,11.0,152947.5909090909,"2246, 5295, 23768, 2248, 2254, 2255, 2549, 3187, 9965, 23769, 53834"]
["Reactome","R-HSA-170834","Signaling by TGF-beta Receptor Complex",0.1974235621715856,0.7090195040115749,74.0,10.0,125592.24324324324,"4088, 9612, 56937, 4092, 5500, 5590, 6497, 3726, 23327, 56288"]
["Reactome","R-HSA-1474228","Degradation of the extracellular matrix",0.2013430786289861,0.7138669234176895,141.0,18.0,141243.97872340426,"80781, 1282, 1284, 2, 960, 1277, 1292, 1303, 1508, 1509, 2006, 3911, 4326, 5654, 6868, 7373, 147968, 170690"]
["KEGG Pathways","hsa05140","Leishmaniasis",0.20164842454769413,0.6188761425509766,70.0,9.0,107954.5,"4792, 7042, 718, 2353, 3553, 3688, 4688, 4790, 6772"]
["KEGG Pathways","hsa00620","Pyruvate metabolism",0.20226683683373378,0.6188761425509766,40.0,6.0,119216.2,"32, 197257, 97, 219, 5091, 84532"]
["Reactome","R-HSA-168928","RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways",0.20229273794739716,0.7138669234176895,84.0,9.0,77495.26190476191,"4792, 1540, 4214, 4790, 6285, 7128, 7186, 8737, 84166"]
["Reactome","R-HSA-74752","Signaling by Insulin receptor",0.20293564522748872,0.7138669234176895,320.0,36.0,142125.4125,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9114, 9965, 51332, 51719, 57731, 245972"]
["Reactome","R-HSA-194223","HDL-mediated lipid transport",0.2051404784674195,0.7138669234176895,19.0,3.0,86081.31578947368,"2, 8029, 81693"]
["Reactome","R-HSA-74751","Insulin receptor signalling cascade",0.20797921466891214,0.7138669234176895,295.0,34.0,148117.27796610168,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 51422, 57521, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 6794, 9048, 9965, 51332, 51719, 57731"]
["Reactome","R-HSA-450294","MAP kinase activation in TLR cascade",0.21059202466115778,0.7138669234176895,64.0,9.0,148191.6875,"6196, 2353, 4208, 4790, 5602, 5606, 5608, 7867, 79155"]
["KEGG Pathways","hsa04060","Cytokine-cytokine receptor interaction",0.21134268969532452,0.6371360498167872,264.0,29.0,117372.52272727272,"3624, 5154, 5618, 7042, 91, 356, 958, 1236, 1435, 1437, 1956, 3082, 3553, 3556, 3596, 4982, 5155, 5159, 6352, 6363, 6387, 7133, 8795, 8995, 9966, 11009, 27190, 27242, 84957"]
["Reactome","R-HSA-912526","Interleukin receptor SHC signaling",0.2121936018114239,0.7138669234176895,253.0,30.0,155703.89723320157,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 8503, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-418346","Platelet homeostasis",0.2123708186133929,0.7138669234176895,88.0,13.0,209135.81818181818,"3708, 6546, 488, 489, 3779, 5023, 5136, 5138, 5739, 7804, 10335, 59345, 100616453"]
["Reactome","R-HSA-438066","Unblocking of NMDA receptor, glutamate binding and activation",0.21306532939170336,0.7138669234176895,17.0,4.0,333662.1176470588,"818, 815, 2893, 2906"]
["Reactome","R-HSA-73848","Pyrimidine metabolism",0.21444940304229979,0.7138669234176895,26.0,4.0,111764.03846153847,"1635, 7378, 51733, 56953"]
["Reactome","R-HSA-5655253","Signaling by FGFR2 in disease",0.2146223405279825,0.7138669234176895,43.0,6.0,138288.44186046513,"2246, 5295, 2248, 2254, 2255, 2549"]
["Reactome","R-HSA-5654693","FRS-mediated FGFR1 signaling",0.21577283995174207,0.7146744819835249,23.0,4.0,128401.65217391304,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-139853","Elevation of cytosolic Ca2+ levels",0.21618737799131604,0.7146744819835249,16.0,3.0,150669.625,"3708, 5023, 100616453"]
["Reactome","R-HSA-5637810","Constitutive Signaling by EGFRvIII",0.22384092875163258,0.7264461089737315,16.0,3.0,163207.0,"5295, 1956, 2549"]
["Reactome","R-HSA-5637812","Signaling by EGFRvIII in Cancer",0.22384092875163258,0.7264461089737315,16.0,3.0,163207.0,"5295, 1956, 2549"]
["Reactome","R-HSA-5218920","VEGFR2 mediated vascular permeability",0.22436889236842048,0.7264461089737315,28.0,5.0,153615.0,"857, 1495, 1499, 5058, 5879"]
["Reactome","R-HSA-211945","Phase 1 - Functionalization of compounds",0.22471366627999453,0.7264461089737315,106.0,12.0,92525.7075471698,"5447, 196, 219, 1545, 5740, 8639, 9915, 10499, 54498, 57491, 64757, 84532"]
["Reactome","R-HSA-112040","G-protein mediated events",0.225124372346161,0.7264461089737315,47.0,8.0,227527.085106383,"5575, 109, 115, 3708, 108, 111, 5136, 23236"]
["Reactome","R-HSA-1834949","Cytosolic sensors of pathogen-associated DNA ",0.2307155412428749,0.7266380112014625,68.0,7.0,70116.94117647059,"4792, 1499, 4790, 6285, 8737, 9208, 171568"]
["Reactome","R-HSA-196854","Metabolism of vitamins and cofactors",0.23123261000136536,0.7266380112014625,170.0,20.0,139938.0,"32, 4337, 60490, 4363, 5091, 5740, 6383, 7804, 8029, 8566, 9227, 9962, 10840, 23057, 23475, 25902, 29967, 60496, 64087, 81693"]
["Reactome","R-HSA-2173789","TGF-beta receptor signaling activates SMADs",0.23173102250332162,0.7266380112014625,32.0,5.0,134920.40625,"4088, 56937, 4092, 5500, 23327"]
["Reactome","R-HSA-5654228","Phospholipase C-mediated cascade; FGFR4",0.23217077680975373,0.7266380112014625,15.0,3.0,145691.0,"2246, 2254, 9965"]
["Reactome","R-HSA-189200","Hexose transport",0.2327694470503908,0.7266380112014625,53.0,6.0,75772.62264150943,"3098, 3101, 6518, 6526, 23225, 23279"]
["Reactome","R-HSA-2559580","Oxidative Stress Induced Senescence",0.23325012940509485,0.7266380112014625,120.0,10.0,61869.1,"23043, 1021, 2353, 5602, 5606, 5608, 7867, 9448, 22955, 23112"]
["Reactome","R-HSA-380972","Energy dependent regulation of mTOR by LKB1-AMPK",0.2381327942104123,0.7306397381322857,28.0,4.0,101256.32142857143,"51422, 57521, 6794, 51719"]
["Reactome","R-HSA-352230","Amino acid transport across the plasma membrane",0.23859003474625054,0.7306397381322857,31.0,5.0,139292.25806451612,"55117, 6533, 8140, 55089, 340024"]
["Reactome","R-HSA-881907","Gastrin-CREB signalling pathway via PKC and MAPK",0.24102273720306125,0.7339312082155189,438.0,51.0,164309.2214611872,"5747, 153090, 623, 818, 1607, 1843, 1909, 1910, 2246, 3708, 5154, 5295, 6196, 8527, 9693, 22821, 284, 624, 747, 815, 885, 886, 1437, 1847, 1902, 1956, 2248, 2254, 2255, 2867, 2906, 3082, 3357, 3667, 5155, 5159, 5536, 5690, 5921, 5998, 6865, 7204, 8503, 8620, 9048, 9965, 11343, 23236, 51332, 57731, 59345"]
["KEGG Pathways","hsa04610","Complement and coagulation cascades",0.24115800471915155,0.6931778471911263,68.0,8.0,122383.83823529411,"623, 2, 624, 718, 728, 966, 5104, 5624"]
["Reactome","R-HSA-2672351","Stimuli-sensing channels",0.2450493669827141,0.7399395690176367,107.0,14.0,148457.20560747664,"845, 4308, 7442, 8737, 8989, 11059, 23327, 23678, 53373, 54795, 80036, 80727, 121601, 219931"]
["KEGG Pathways","hsa04142","Lysosome",0.24652258640830102,0.6931778471911263,120.0,12.0,81401.275,"2581, 5660, 6272, 1508, 1509, 2760, 3074, 6609, 7805, 9114, 10947, 245972"]
["Reactome","R-HSA-190241","FGFR2 ligand binding and activation",0.24760687328063122,0.7422556489278626,20.0,4.0,191426.45,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-1168372","Downstream signaling events of B Cell Receptor (BCR)",0.2517264199310701,0.7422556489278626,196.0,23.0,143958.443877551,"2246, 4792, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 4790, 5155, 5159, 5305, 5690, 8503, 9965, 10892, 23112"]
["Reactome","R-HSA-140875","Common Pathway of Fibrin Clot Formation",0.256223371788372,0.7465699862620758,22.0,3.0,168059.54545454544,"5104, 5624, 5657"]
["Reactome","R-HSA-6807004","Negative regulation of MET activity",0.26150210692419046,0.7518185574070476,21.0,4.0,178888.38095238095,"26018, 3082, 5795, 9146"]
["KEGG Pathways","hsa05310","Asthma",0.26638616111974134,0.7185416188098286,28.0,3.0,41599.92857142857,"958, 3596, 5553"]
["Reactome","R-HSA-199992","trans-Golgi Network Vesicle Budding",0.2676488499655741,0.7581762820374476,73.0,9.0,112935.24657534246,"6272, 51429, 7164, 8301, 9026, 9146, 9698, 10618, 26258"]
["Reactome","R-HSA-421837","Clathrin derived vesicle budding",0.2676488499655741,0.7581762820374476,73.0,9.0,112935.24657534246,"6272, 51429, 7164, 8301, 9026, 9146, 9698, 10618, 26258"]
["Reactome","R-HSA-6804758","Regulation of TP53 Activity through Acetylation",0.2693244147108047,0.7581762820374476,31.0,4.0,85332.09677419355,"1108, 3622, 5305, 5608"]
["Reactome","R-HSA-189445","Metabolism of porphyrins",0.2730439153144129,0.763994201177694,17.0,2.0,45069.17647058824,"211, 2235"]
["Reactome","R-HSA-383280","Nuclear Receptor transcription pathway",0.2736191230061859,0.763994201177694,51.0,8.0,261318.58823529413,"2908, 2099, 3164, 4929, 5914, 6096, 7067, 10002"]
["Reactome","R-HSA-166166","MyD88-independent TLR3/TLR4 cascade ",0.27579065292633914,0.763994201177694,99.0,12.0,136191.9090909091,"4792, 6196, 2353, 4208, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["Reactome","R-HSA-168164","Toll Like Receptor 3 (TLR3) Cascade",0.27579065292633914,0.763994201177694,99.0,12.0,136191.9090909091,"4792, 6196, 2353, 4208, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["Reactome","R-HSA-937061","TRIF-mediated TLR3/TLR4 signaling ",0.27579065292633914,0.763994201177694,99.0,12.0,136191.9090909091,"4792, 6196, 2353, 4208, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["Reactome","R-HSA-167044","Signalling to RAS",0.27873999155204965,0.7659179931017566,254.0,29.0,150775.98031496062,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 7867, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-8853659","RET signaling",0.2791597495671527,0.7659179931017566,267.0,31.0,158236.28464419476,"5747, 153090, 818, 1843, 2246, 5154, 5295, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2549, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 8503, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-389958","Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding",0.2810891643385941,0.7683749104905647,32.0,3.0,42977.65625,"5201, 6950, 10694"]
["Reactome","R-HSA-5689896","Ovarian tumor domain proteases",0.2831696843769092,0.7683749104905647,37.0,5.0,120502.27027027027,"2099, 7128, 8737, 10318, 79155"]
["Reactome","R-HSA-5655332","Signaling by FGFR3 in disease",0.28628130501874277,0.7683749104905647,22.0,4.0,179138.0,"2246, 5295, 2254, 2549"]
["Reactome","R-HSA-8853338","Signaling by FGFR3 point mutants in cancer",0.28628130501874277,0.7683749104905647,22.0,4.0,179138.0,"2246, 5295, 2254, 2549"]
["KEGG Pathways","hsa04350","TGF-beta signaling pathway",0.2869049249758168,0.7238720894642333,84.0,13.0,218078.58333333334,"4088, 3624, 4092, 4838, 7042, 7058, 653, 654, 3398, 3399, 4052, 7057, 7060"]
["Reactome","R-HSA-112412","SOS-mediated signalling",0.2885110134829839,0.7683749104905647,243.0,28.0,154209.58847736625,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-179812","GRB2 events in EGFR signaling",0.2885110134829839,0.7683749104905647,243.0,28.0,154209.58847736625,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-180336","SHC1 events in EGFR signaling",0.2885110134829839,0.7683749104905647,243.0,28.0,154209.58847736625,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-5673001","RAF/MAP kinase cascade",0.2885110134829839,0.7683749104905647,243.0,28.0,154209.58847736625,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-6814122","Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding",0.29025237519106084,0.7683749104905647,43.0,5.0,98789.44186046511,"6000, 6950, 8787, 10694, 59345"]
["Reactome","R-HSA-2453902","The canonical retinoid cycle in rods (twilight vision)",0.2907172418044782,0.7683749104905647,22.0,3.0,74860.72727272728,"9227, 64220, 157506"]
["Reactome","R-HSA-535734","Fatty acid, triacylglycerol, and ketone body metabolism",0.29143425346544827,0.7683912877954868,247.0,27.0,130822.06477732793,"9612, 51586, 56894, 32, 51422, 196, 211, 948, 2274, 3992, 4862, 7003, 7004, 7005, 9524, 9915, 10413, 10499, 10555, 23389, 26230, 27063, 27242, 29841, 57491, 65985, 253558"]
["Reactome","R-HSA-166016","Toll Like Receptor 4 (TLR4) Cascade",0.29381891798847637,0.7709180833629684,128.0,15.0,136019.5,"4792, 6196, 57161, 948, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["Reactome","R-HSA-442729","CREB phosphorylation through the activation of CaMKII",0.2979106656276922,0.77926027897641,16.0,3.0,166825.8125,"818, 815, 2906"]
["Reactome","R-HSA-202433","Generation of second messenger molecules",0.29935029798881685,0.77926027897641,31.0,4.0,82041.19354838709,"9398, 3937, 5058, 55740"]
["Reactome","R-HSA-1912420","Pre-NOTCH Processing in Golgi",0.3010751323795913,0.77926027897641,18.0,3.0,204256.05555555556,"488, 489, 6487"]
["KEGG Pathways","hsa05146","Amoebiasis",0.3086304939938237,0.7238720894642333,105.0,15.0,175792.04761904763,"87, 1282, 1284, 5747, 81, 5295, 7042, 1277, 1437, 3553, 3908, 3911, 4790, 8503, 23236"]
["KEGG Pathways","hsa04670","Leukocyte transendothelial migration",0.30965916483662714,0.7238720894642333,116.0,15.0,162723.1551724138,"87, 5747, 9564, 81, 5295, 1495, 1499, 3688, 4688, 5879, 6387, 8503, 10627, 29895, 49861"]
["KEGG Pathways","hsa00562","Inositol phosphate metabolism",0.31001732986786457,0.7238720894642333,57.0,8.0,146471.98245614034,"3632, 3705, 3707, 8871, 5305, 5333, 23236, 51196"]
["Reactome","R-HSA-3906995","Diseases associated with O-glycosylation of proteins",0.3155001777270977,0.796233593871341,53.0,9.0,223835.30188679244,"7058, 9509, 7057, 9508, 10417, 54437, 79875, 170690, 170691"]
["Reactome","R-HSA-114508","Effects of PIP2 hydrolysis",0.32113043494507526,0.8044701860618094,27.0,5.0,205687.96296296295,"1607, 3708, 8527, 747, 11343"]
["Reactome","R-HSA-983231","Factors involved in megakaryocyte development and platelet production",0.3238087489305955,0.8061876527888009,170.0,17.0,117437.25882352941,"5575, 10938, 832, 3705, 23414, 30846, 55619, 1062, 1794, 3797, 5879, 7465, 7975, 8165, 23764, 25970, 51317"]
["Reactome","R-HSA-2559583","Cellular Senescence",0.32619961218602483,0.8061876527888009,189.0,16.0,93224.1746031746,"3490, 6196, 23043, 1021, 1027, 2113, 2114, 2353, 4790, 5602, 5606, 5608, 7867, 9448, 22955, 23112"]
["Reactome","R-HSA-1236382","Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants",0.3283669165809104,0.8061876527888009,20.0,3.0,139120.6,"5295, 1956, 2549"]
["Reactome","R-HSA-1643713","Signaling by EGFR in Cancer",0.3283669165809104,0.8061876527888009,20.0,3.0,139120.6,"5295, 1956, 2549"]
["Reactome","R-HSA-5637815","Signaling by Ligand-Responsive EGFR Variants in Cancer",0.3283669165809104,0.8061876527888009,20.0,3.0,139120.6,"5295, 1956, 2549"]
["KEGG Pathways","hsa05145","Toxoplasmosis",0.3311414059191907,0.7589140894080312,129.0,15.0,132499.34108527133,"598, 4792, 5295, 7042, 958, 3688, 3908, 3911, 4790, 5602, 5606, 5608, 6772, 8398, 8503"]
["Reactome","R-HSA-5654699","SHC-mediated cascade:FGFR2",0.3330436619570942,0.8100188543559214,23.0,4.0,177969.91304347827,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-5669034","TNFs bind their physiological receptors",0.3335860271121806,0.8100188543559214,28.0,4.0,119493.5,"4982, 7133, 8995, 9966"]
["Reactome","R-HSA-418597","G alpha (z) signalling events",0.33899675266340584,0.8163218559347607,47.0,7.0,158235.8510638298,"109, 115, 5999, 108, 111, 152, 59345"]
["Reactome","R-HSA-190861","Gap junction assembly",0.33906430463895243,0.8163218559347607,35.0,4.0,79180.62857142858,"2701, 10052, 84694, 219770"]
["Reactome","R-HSA-170984","ARMS-mediated activation",0.3401352634140402,0.8170804883346166,247.0,28.0,153999.84615384616,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-163685","Integration of energy metabolism",0.34095116136555137,0.8172244022974746,110.0,14.0,156052.4909090909,"5575, 32, 109, 115, 3708, 51422, 108, 111, 152, 6794, 9254, 23236, 26251, 59345"]
["Reactome","R-HSA-1643685","Disease",0.34251719309783785,0.8188322065188307,840.0,81.0,130581.09166666666,"23164, 182, 1488, 9734, 4088, 7100, 9612, 54492, 55534, 153090, 928, 2246, 4792, 5154, 5295, 6122, 6776, 7058, 9509, 22821, 22906, 23493, 28514, 356, 948, 1027, 1104, 1499, 1523, 1794, 1956, 2248, 2254, 2255, 2309, 2549, 2957, 3082, 3164, 3667, 4000, 4790, 4836, 5091, 5155, 5159, 5606, 5608, 5690, 5879, 5921, 6123, 6159, 6383, 6772, 6777, 6868, 6873, 6881, 7057, 8029, 8503, 9146, 9208, 9444, 9508, 9759, 9965, 10417, 23225, 23279, 23327, 23499, 26508, 54437, 64087, 64220, 79875, 81693, 170690, 170691"]
["Reactome","R-HSA-187706","Signalling to p38 via RIT and RIN",0.3450671830835926,0.8188322065188307,247.0,28.0,155343.54655870446,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-168898","Toll-Like Receptors Cascades",0.34523536990898646,0.8188322065188307,155.0,17.0,134200.06451612903,"7100, 4792, 6196, 57161, 948, 1508, 2353, 4208, 4214, 4790, 5602, 5606, 5608, 6285, 7867, 8737, 79155"]
["Reactome","R-HSA-5654708","Downstream signaling of activated FGFR3",0.3454093304094235,0.8188322065188307,25.0,4.0,161992.28,"2246, 5295, 2254, 2549"]
["Reactome","R-HSA-446652","Interleukin-1 signaling",0.3515176434821812,0.8220310126304863,45.0,6.0,131087.3111111111,"57161, 3553, 3556, 4790, 5608, 79155"]
["Reactome","R-HSA-390471","Association of TriC/CCT with target proteins during biosynthesis",0.35188165424320617,0.8220310126304863,40.0,4.0,68673.975,"6950, 8877, 10694, 63971"]
["Reactome","R-HSA-5684996","MAPK1/MAPK3 signaling",0.35208173806467635,0.8220310126304863,249.0,28.0,152612.5421686747,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-170968","Frs2-mediated activation",0.3577184065780813,0.8227523351295869,248.0,28.0,154353.35483870967,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-6782315","tRNA modification in the nucleus and cytosol",0.35848259212433037,0.8227594099498963,41.0,4.0,72606.29268292683,"1787, 80324, 115708, 152992"]
["Reactome","R-HSA-5357769","Caspase activation via extrinsic apoptotic signalling pathway",0.3605690969182234,0.822958491559215,28.0,4.0,184142.75,"356, 7186, 8737, 8795"]
["Reactome","R-HSA-2979096","NOTCH2 Activation and Transmission of Signal to the Nucleus",0.36085321461523395,0.822958491559215,21.0,3.0,130755.95238095238,"182, 54492, 28514"]
["Reactome","R-HSA-2262752","Cellular responses to stress",0.36263473467972046,0.8252803119763744,441.0,36.0,86654.7052154195,"2034, 818, 3091, 3490, 6196, 23043, 51422, 57521, 84962, 768, 815, 1021, 1027, 2113, 2114, 2353, 2950, 3308, 4688, 4790, 5602, 5606, 5608, 5690, 6649, 7867, 9448, 10049, 22863, 22955, 23112, 23225, 23279, 50507, 55054, 84971"]
["Reactome","R-HSA-379716","Cytosolic tRNA aminoacylation",0.36595104300513104,0.8258728131284899,24.0,3.0,91803.54166666667,"833, 2617, 6301"]
["Reactome","R-HSA-373752","Netrin-1 signaling",0.368453027062577,0.8297164201284034,42.0,8.0,393377.0238095238,"5747, 6477, 6586, 9353, 4651, 5306, 5879, 7204"]
["Reactome","R-HSA-381038","XBP1(S) activates chaperone genes",0.37234296552534646,0.8333390180805373,53.0,5.0,59775.67924528302,"2137, 4000, 7709, 9114, 116138"]
["Reactome","R-HSA-187687","Signalling to ERKs",0.3736149575233285,0.8340009262803821,261.0,29.0,151769.6398467433,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 7867, 9048, 9965, 51332, 57731"]
["Reactome","R-HSA-3299685","Detoxification of Reactive Oxygen Species",0.3749532379021885,0.8340009262803821,37.0,4.0,68994.56756756757,"2950, 4688, 6649, 50507"]
["Reactome","R-HSA-3928662","EPHB-mediated forward signaling",0.3775698811217861,0.8357640590919769,41.0,6.0,206414.48780487804,"5747, 2047, 5058, 5879, 5921, 6383"]
["Reactome","R-HSA-1839126","FGFR2 mutant receptor activation",0.3782556517238955,0.8357640590919769,33.0,4.0,120859.24242424243,"2246, 2248, 2254, 2255"]
["KEGG Pathways","hsa04150","mTOR signaling pathway",0.3802995176377138,0.8062424983400798,52.0,7.0,140088.32692307694,"3091, 5295, 6196, 57521, 6794, 8503, 51719"]
["Reactome","R-HSA-2173795","Downregulation of SMAD2/3:SMAD4 transcriptional activity",0.3811578918893105,0.8357640590919769,23.0,4.0,164188.21739130435,"4088, 9612, 6497, 23327"]
["Reactome","R-HSA-169893","Prolonged ERK activation events",0.38462610718923534,0.8399612563061887,250.0,28.0,154106.812,"5747, 153090, 818, 1843, 2246, 5154, 9693, 22821, 284, 815, 1437, 1847, 1956, 2248, 2254, 2255, 2906, 3082, 3667, 5155, 5159, 5536, 5690, 5921, 9048, 9965, 51332, 57731"]
["KEGG Pathways","hsa04910","Insulin signaling pathway",0.38614725655156484,0.8062424983400798,137.0,16.0,142286.82481751824,"5575, 32, 3098, 5295, 5500, 5590, 51422, 57521, 3101, 3667, 5257, 5602, 6655, 8503, 10603, 80201"]
["Reactome","R-HSA-983705","Signaling by the B Cell Receptor (BCR)",0.38687440015430125,0.8421417037114082,226.0,25.0,144254.14159292035,"2246, 3708, 4792, 5154, 5295, 1027, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 4790, 5155, 5159, 5305, 5690, 8503, 9965, 10892, 23112, 100616453"]
["Reactome","R-HSA-5689880","Ub-specific processing proteases",0.3892523213493331,0.8432500187948478,212.0,18.0,95435.2075471698,"4088, 3091, 4092, 4792, 55031, 154, 1540, 5690, 6881, 7186, 7874, 8607, 8737, 9099, 9146, 9804, 9960, 10600"]
["Reactome","R-HSA-2173793","Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",0.3926933071986634,0.8473083135364374,45.0,6.0,122202.6888888889,"4088, 9612, 4092, 6497, 3726, 23327"]
["KEGG Pathways","hsa05213","Endometrial cancer",0.3951180296757489,0.8063365984318788,52.0,8.0,209216.92307692306,"595, 5295, 1495, 1499, 1956, 2309, 6655, 8503"]
["KEGG Pathways","hsa05210","Colorectal cancer",0.39726827532497444,0.8063365984318788,62.0,9.0,195785.7258064516,"4088, 595, 5295, 7042, 1499, 2353, 5602, 5879, 8503"]
["Reactome","R-HSA-442982","Ras activation uopn Ca2+ infux through NMDA receptor",0.39796857674037556,0.8527283277010309,18.0,3.0,164425.05555555556,"818, 815, 2906"]
["Reactome","R-HSA-210993","Tie2 Signaling",0.4042569834773108,0.8527283277010309,18.0,3.0,200908.94444444444,"285, 5295, 284"]
["Reactome","R-HSA-2214320","Anchoring fibril formation",0.4052739120225787,0.8527283277010309,17.0,3.0,180787.29411764705,"1282, 1284, 1277"]
["Reactome","R-HSA-375280","Amine ligand-binding receptors",0.40572776769035074,0.8527283277010309,40.0,7.0,289531.425,"152, 153, 154, 1814, 3274, 3357, 3363"]
["Reactome","R-HSA-1912422","Pre-NOTCH Expression and Processing",0.4070377586436003,0.8527283277010309,46.0,6.0,147886.73913043478,"55534, 595, 488, 489, 6487, 23112"]
["Reactome","R-HSA-977606","Regulation of Complement cascade",0.4079229022083945,0.8529297046175521,27.0,3.0,146265.62962962964,"718, 728, 966"]
["Reactome","R-HSA-418555","G alpha (s) signalling events",0.410122715904386,0.8532158176370986,143.0,17.0,154835.06993006993,"109, 115, 7434, 108, 111, 153, 154, 3274, 3363, 5136, 5138, 5734, 5739, 27115, 53831, 59345, 122876"]
["Reactome","R-HSA-3371571","HSF1-dependent transactivation",0.41214213545178924,0.8532158176370986,25.0,3.0,89881.24,"818, 57521, 815"]
["KEGG Pathways","hsa05160","Hepatitis C",0.4125238299778847,0.8254861912666204,134.0,14.0,94651.5895522388,"4792, 5295, 975, 1956, 4790, 5520, 5522, 5602, 6655, 6772, 7186, 8503, 8737, 49861"]
["Reactome","R-HSA-5654719","SHC-mediated cascade:FGFR4",0.4137422952059752,0.8532158176370986,20.0,3.0,128581.45,"2246, 2254, 9965"]
["KEGG Pathways","hsa00561","Glycerolipid metabolism",0.414756476587619,0.8254861912666204,50.0,7.0,150737.94,"56894, 1607, 8527, 219, 10555, 11343, 253558"]
["Reactome","R-HSA-195258","RHO GTPase Effectors",0.4150781441247822,0.8532158176370986,303.0,27.0,113227.82508250825,"4627, 4638, 5747, 8379, 91010, 5500, 752, 1027, 1062, 1495, 1499, 3688, 4085, 4629, 4637, 4688, 5058, 5879, 10458, 10499, 10971, 23081, 23191, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-381070","IRE1alpha activates chaperones",0.416741860973532,0.8532158176370986,55.0,5.0,59299.181818181816,"2137, 4000, 7709, 9114, 116138"]
["Reactome","R-HSA-392154","Nitric oxide stimulates guanylate cyclase",0.42204597260515914,0.8549330292029931,24.0,5.0,323804.25,"3708, 3779, 5136, 5138, 10335"]
["Reactome","R-HSA-73923","Lipid digestion, mobilization, and transport",0.4224602578623602,0.8549330292029931,110.0,11.0,105497.86363636363,"5046, 5500, 2, 857, 2172, 4547, 5346, 8029, 11343, 51099, 81693"]
["Reactome","R-HSA-5654700","FRS-mediated FGFR2 signaling",0.4234539718800419,0.8549330292029931,25.0,4.0,171833.52,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-399954","Sema3A PAK dependent Axon repulsion",0.4239075889480151,0.8549330292029931,16.0,3.0,275779.8125,"5058, 5879, 8829"]
["Reactome","R-HSA-391903","Eicosanoid ligand-binding receptors",0.42473148983567455,0.8549995167828011,15.0,2.0,115542.0,"5734, 5739"]
["Reactome","R-HSA-373755","Semaphorin interactions",0.42752527098631676,0.8590238251602388,67.0,9.0,212509.58208955225,"4627, 23129, 3688, 4629, 4637, 5058, 5364, 5879, 8829"]
["KEGG Pathways","hsa00410","beta-Alanine metabolism",0.4337328347594104,0.8388229351479163,22.0,3.0,103368.77272727272,"219, 8639, 51733"]
["Reactome","R-HSA-418990","Adherens junctions interactions",0.43473295150342706,0.8634600281396245,33.0,6.0,639459.4242424242,"1000, 1007, 1012, 1495, 1499, 5817"]
["Reactome","R-HSA-445095","Interaction between L1 and Ankyrins",0.4353244360185896,0.8634600281396245,31.0,5.0,176319.2258064516,"23114, 286, 288, 51332, 57731"]
["Reactome","R-HSA-400042","Adrenaline,noradrenaline inhibits insulin secretion",0.43989596660995917,0.8639489473616185,28.0,4.0,147653.67857142858,"111, 152, 9254, 59345"]
["KEGG Pathways","hsa00240","Pyrimidine metabolism",0.44254061198579997,0.8427032954039387,98.0,9.0,76585.55102040817,"956, 1635, 7378, 10201, 51733, 54963, 56655, 56953, 171568"]
["KEGG Pathways","hsa04914","Progesterone-mediated oocyte maturation",0.44396076050548966,0.8427032954039387,85.0,11.0,169663.2,"8379, 109, 115, 5295, 6196, 108, 111, 3480, 4085, 5602, 8503"]
["Reactome","R-HSA-1963642","PI3K events in ERBB2 signaling",0.44500528127404815,0.865183385985311,16.0,3.0,394094.8125,"5295, 1956, 2549"]
["Reactome","R-HSA-2559585","Oncogene Induced Senescence",0.4499299809004799,0.8669773785265933,32.0,4.0,115949.53125,"1021, 2113, 2114, 23112"]
["Reactome","R-HSA-1368108","BMAL1:CLOCK,NPAS2 activates circadian gene expression",0.45359321827582766,0.8691902248354278,47.0,7.0,218111.72340425532,"2908, 3091, 8553, 28999, 4862, 10499, 150094"]
["Reactome","R-HSA-375276","Peptide ligand-binding receptors",0.45542237636650384,0.8691902248354278,187.0,20.0,130700.21390374332,"1889, 623, 1909, 1910, 2852, 5660, 624, 718, 728, 885, 886, 1236, 1325, 5368, 6352, 6363, 6387, 6865, 8620, 339403"]
["Reactome","R-HSA-199220","Vitamin B5 (pantothenate) metabolism",0.45946287518142154,0.8713673124054678,17.0,2.0,85693.76470588235,"60490, 60496"]
["Reactome","R-HSA-430039","mRNA decay by 5' to 3' exoribonuclease",0.46363285460583376,0.8762012514491369,15.0,2.0,82457.6,"27258, 196513"]
["Reactome","R-HSA-450302","activated TAK1 mediates p38 MAPK activation",0.4699280978591754,0.8833792309498087,24.0,3.0,134060.41666666666,"5606, 5608, 7867"]
["Reactome","R-HSA-391251","Protein folding",0.47071432798121754,0.8833792309498087,103.0,9.0,81230.84466019417,"5201, 6000, 6904, 6950, 8787, 8877, 10694, 59345, 63971"]
["KEGG Pathways","hsa04966","Collecting duct acid secretion",0.4712673172975814,0.8491779749863747,27.0,3.0,66427.55555555556,"9114, 10723, 245972"]
["Reactome","R-HSA-1566948","Elastic fibre formation",0.4747054429438046,0.884752730728022,44.0,6.0,151321.81818181818,"7042, 2006, 3678, 3688, 4017, 4052"]
["Reactome","R-HSA-1650814","Collagen biosynthesis and modifying enzymes",0.4814825029191273,0.8897800061435712,70.0,10.0,202314.55714285714,"80781, 1282, 1284, 9509, 1277, 1292, 1303, 7373, 9508, 10536"]
["Reactome","R-HSA-877300","Interferon gamma signaling",0.483194434127889,0.8897800061435712,91.0,9.0,108617.16483516483,"818, 815, 960, 3394, 3662, 6672, 6772, 23321, 163351"]
["Reactome","R-HSA-389960","Formation of tubulin folding intermediates by CCT/TriC",0.48386068790033465,0.8897800061435712,25.0,2.0,39526.16,"6950, 10694"]
["Reactome","R-HSA-5674400","Constitutive Signaling by AKT1 E17K in Cancer",0.48737883820223676,0.8929771594857931,25.0,3.0,101099.92,"1027, 2309, 3164"]
["Reactome","R-HSA-6811436","COPI-independent Golgi-to-ER retrograde traffic",0.4907957343699965,0.8960054205138521,45.0,5.0,132790.8,"56894, 2590, 8398, 10540, 23299"]
["KEGG Pathways","hsa04622","RIG-I-like receptor signaling pathway",0.4917457321732172,0.8491779749863747,71.0,7.0,89279.85915492958,"4792, 1540, 4214, 4790, 5602, 7186, 8737"]
["Reactome","R-HSA-6791312","TP53 Regulates Transcription of Cell Cycle Genes",0.4923473600068882,0.8960054205138521,49.0,5.0,88258.26530612246,"1027, 1820, 4850, 10769, 144455"]
["Reactome","R-HSA-196741","Cobalamin (Cbl, vitamin B12) transport and metabolism",0.4940048386921886,0.8960054205138521,21.0,3.0,153340.7142857143,"4363, 8029, 81693"]
["KEGG Pathways","hsa04960","Aldosterone-regulated sodium reabsorption",0.49669027313770114,0.8491779749863747,42.0,6.0,181357.7857142857,"5295, 477, 486, 3667, 8503, 23327"]
["Reactome","R-HSA-182971","EGFR downregulation",0.4974377896258127,0.9007206877479121,25.0,4.0,268836.36,"8874, 1956, 5782, 9146"]
["Reactome","R-HSA-157858","Gap junction trafficking and regulation",0.4989865303873311,0.9012191850566909,48.0,5.0,95243.4375,"2701, 7082, 10052, 84694, 219770"]
["KEGG Pathways","hsa00500","Starch and sucrose metabolism",0.501222121821226,0.8491779749863747,52.0,6.0,185863.0,"3098, 2595, 2632, 3101, 80146, 80201"]
["Reactome","R-HSA-159236","Transport of Mature mRNA derived from an Intron-Containing Transcript",0.5080647446256312,0.9070911830265367,71.0,6.0,70813.2957746479,"6430, 10212, 10250, 23225, 23279, 84248"]
["Reactome","R-HSA-2022870","Chondroitin sulfate biosynthesis",0.5080757840460401,0.9070911830265367,21.0,3.0,167705.85714285713,"22856, 166012, 337876"]
["Reactome","R-HSA-8862803","Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models",0.5085081007530816,0.9070911830265367,22.0,3.0,127360.5,"356, 2309, 4000"]
["Reactome","R-HSA-8863678","Neurodegenerative Diseases",0.5085081007530816,0.9070911830265367,22.0,3.0,127360.5,"356, 2309, 4000"]
["Reactome","R-HSA-5676594","TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway",0.5128249882833784,0.9087931349743148,17.0,2.0,79650.76470588235,"958, 7186"]
["Reactome","R-HSA-70895","Branched-chain amino acid catabolism",0.518680516422185,0.9133278987106366,23.0,3.0,128410.08695652174,"586, 8424, 64087"]
["Reactome","R-HSA-917977","Transferrin endocytosis and recycling",0.5236249525553378,0.9133278987106366,30.0,3.0,70901.13333333333,"9114, 245972, 261729"]
["Reactome","R-HSA-5654743","Signaling by FGFR4",0.5238328373733531,0.9133278987106366,41.0,5.0,175868.46341463414,"2246, 5295, 2254, 2549, 9965"]
["KEGG Pathways","hsa05014","Amyotrophic lateral sclerosis (ALS)",0.5262100075901668,0.8607006249037953,53.0,6.0,129011.24528301887,"598, 2906, 5606, 5608, 5879, 7133"]
["Reactome","R-HSA-5173105","O-linked glycosylation",0.527479611210683,0.914737433754008,108.0,15.0,220492.5,"7058, 9509, 2590, 6482, 6487, 7057, 9508, 10417, 54437, 79875, 117248, 146712, 170690, 170691, 256435"]
["Reactome","R-HSA-5654712","FRS-mediated FGFR4 signaling",0.5288722443073589,0.914737433754008,22.0,3.0,126098.13636363637,"2246, 2254, 9965"]
["KEGG Pathways","hsa05131","Shigellosis",0.5290159938433083,0.8607006249037953,61.0,7.0,152597.1475409836,"4792, 960, 3678, 3688, 4790, 5602, 5879"]
["Reactome","R-HSA-977068","Termination of O-glycan biosynthesis",0.5372536474698023,0.9203022808952115,21.0,3.0,145048.90476190476,"6482, 6487, 256435"]
["KEGG Pathways","hsa04662","B cell receptor signaling pathway",0.5376271193274492,0.8617761991372311,75.0,9.0,122131.16,"4792, 5295, 975, 2353, 4790, 5879, 6655, 8503, 10892"]
["Reactome","R-HSA-1592230","Mitochondrial biogenesis",0.537629378488358,0.9203022808952115,54.0,6.0,152307.96296296295,"4209, 51422, 211, 4208, 10499, 64784"]
["Reactome","R-HSA-5688426","Deubiquitination",0.5384182026842715,0.9203022808952115,289.0,24.0,102133.26989619377,"4088, 3091, 4092, 4792, 55031, 154, 1540, 2099, 5690, 6881, 7128, 7186, 7874, 8607, 8737, 9099, 9146, 9804, 9960, 10318, 10600, 79155, 114803, 221937"]
["Reactome","R-HSA-3214841","PKMTs methylate histone lysines",0.5401203948854832,0.9203022808952115,70.0,6.0,96912.94285714286,"4790, 7468, 54904, 55904, 63976, 64754"]
["Reactome","R-HSA-450282","MAPK targets/ Nuclear events mediated by MAP kinases",0.5410766540105791,0.9203022808952115,31.0,4.0,157652.25806451612,"6196, 2353, 4208, 5602"]
["KEGG Pathways","hsa04964","Proximal tubule bicarbonate reclamation",0.5436201462620159,0.8638924804939012,23.0,3.0,147494.86956521738,"358, 477, 486"]
["Reactome","R-HSA-165159","mTOR signalling",0.5439585439510042,0.9203022808952115,39.0,4.0,88661.58974358975,"51422, 57521, 6794, 51719"]
["Reactome","R-HSA-5687128","MAPK6/MAPK4 signaling",0.5440084713154858,0.9203022808952115,89.0,9.0,115028.37078651685,"989, 2309, 5058, 5690, 5879, 8555, 8556, 10602, 23112"]
["Reactome","R-HSA-1980145","Signaling by NOTCH2",0.56978578415675,0.9490576774629379,33.0,4.0,130322.54545454546,"182, 54492, 55534, 28514"]
["KEGG Pathways","hsa05130","Pathogenic Escherichia coli infection",0.5777147130879364,0.8774105661570508,55.0,6.0,141163.03636363638,"7100, 8440, 1499, 3688, 9181, 10971"]
["Reactome","R-HSA-198933","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",0.5823745899172136,0.9534029661523924,124.0,9.0,56103.91129032258,"718, 947, 958, 975, 1277, 3688, 5817, 6614, 9976"]
["KEGG Pathways","hsa00592","alpha-Linolenic acid metabolism",0.5867551102136831,0.8774105661570508,19.0,2.0,155358.73684210525,"8310, 8398"]
["Reactome","R-HSA-5654726","Negative regulation of FGFR1 signaling",0.588376111186375,0.9534029661523924,33.0,4.0,174072.84848484848,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-390466","Chaperonin-mediated protein folding",0.5885970956416748,0.9534029661523924,97.0,8.0,79877.71134020618,"5201, 6000, 6950, 8787, 8877, 10694, 59345, 63971"]
["Reactome","R-HSA-180746","Nuclear import of Rev protein",0.5916837251344371,0.9534029661523924,32.0,3.0,80495.6875,"1104, 23225, 23279"]
["KEGG Pathways","hsa05223","Non-small cell lung cancer",0.591745156644631,0.8774105661570508,54.0,7.0,164862.87037037036,"595, 5295, 1021, 1956, 2309, 6655, 8503"]
["Reactome","R-HSA-5663213","RHO GTPases Activate WASPs and WAVEs",0.5918099957280104,0.9534029661523924,36.0,4.0,91333.66666666667,"5747, 5879, 10458, 23191"]
["KEGG Pathways","hsa00520","Amino sugar and nucleotide sugar metabolism",0.5926118234620925,0.8774105661570508,47.0,5.0,97195.14893617021,"3098, 3074, 3101, 80146, 80201"]
["Reactome","R-HSA-2029482","Regulation of actin dynamics for phagocytic cup formation",0.5928102320550562,0.9534029661523924,61.0,7.0,125379.26229508196,"4627, 5747, 4651, 5058, 5879, 10458, 23191"]
["KEGG Pathways","hsa04916","Melanogenesis",0.5949271643699028,0.8774105661570508,100.0,13.0,193784.11,"109, 115, 818, 1910, 108, 111, 815, 1499, 7299, 7474, 7477, 8324, 23236"]
["Reactome","R-HSA-392851","Prostacyclin signalling through prostacyclin receptor",0.5961801842632044,0.9534029661523924,19.0,2.0,71283.78947368421,"5739, 59345"]
["Reactome","R-HSA-109703","PKB-mediated events",0.5973771029198801,0.9534029661523924,40.0,4.0,89491.275,"51422, 57521, 6794, 51719"]
["Reactome","R-HSA-2173791","TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)",0.5977186929046638,0.9534029661523924,16.0,2.0,166002.5,"5590, 56288"]
["KEGG Pathways","hsa04145","Phagosome",0.6001008005350608,0.8787190293549103,149.0,14.0,103149.9798657718,"7058, 718, 948, 3678, 3688, 4481, 4688, 5879, 7057, 7060, 9114, 9146, 64581, 245972"]
["Reactome","R-HSA-2029480","Fcgamma receptor (FCGR) dependent phagocytosis",0.6002537362288881,0.9534029661523924,86.0,10.0,142448.17441860464,"4627, 5747, 3708, 5295, 4651, 5058, 5879, 8398, 10458, 23191"]
["Reactome","R-HSA-202403","TCR signaling",0.6096371253874552,0.9537751246993038,116.0,11.0,105245.9051724138,"4792, 5295, 9398, 997, 3937, 4790, 5058, 5690, 5795, 10892, 55740"]
["KEGG Pathways","hsa04110","Cell cycle",0.6096634141778654,0.8789952944074227,123.0,13.0,105025.28455284552,"4088, 8379, 595, 7042, 1021, 1027, 4085, 4616, 7465, 7709, 8555, 8556, 10971"]
["Reactome","R-HSA-416476","G alpha (q) signalling events",0.6115336971362577,0.9537751246993038,189.0,22.0,174352.84656084655,"623, 1607, 1909, 1910, 3708, 5295, 8527, 624, 747, 885, 886, 1902, 2867, 3357, 5998, 6865, 7204, 8503, 8620, 11343, 23236, 59345"]
["Reactome","R-HSA-5576893","Phase 2 - plateau phase",0.6144118628845113,0.9537751246993038,28.0,4.0,183881.60714285713,"779, 781, 782, 9254"]
["Reactome","R-HSA-70153","Glucose transport",0.6146034543581165,0.9537751246993038,45.0,4.0,76007.28888888888,"3098, 3101, 23225, 23279"]
["KEGG Pathways","hsa04977","Vitamin digestion and absorption",0.6179822998862021,0.8789952944074227,24.0,3.0,159463.875,"4363, 8029, 9227"]
["Reactome","R-HSA-442742","CREB phosphorylation through the activation of Ras",0.6228202187387962,0.9614403062839793,28.0,4.0,183128.2857142857,"818, 6196, 815, 2906"]
["Reactome","R-HSA-5626467","RHO GTPases activate IQGAPs",0.6240773458814446,0.9614403062839793,31.0,3.0,81953.93548387097,"1495, 1499, 5879"]
["KEGG Pathways","hsa04970","Salivary secretion",0.6260161608950425,0.8789952944074227,86.0,11.0,216330.06976744186,"109, 115, 3708, 108, 111, 153, 154, 362, 477, 486, 23236"]
["Reactome","R-HSA-372708","p130Cas linkage to MAPK signaling for integrins",0.6267929732131114,0.9614403062839793,15.0,2.0,118463.4,"5747, 9564"]
["Reactome","R-HSA-2028269","Signaling by Hippo",0.628641724584297,0.9614403062839793,21.0,3.0,163167.7619047619,"6788, 7082, 10413"]
["Reactome","R-HSA-73980","RNA Polymerase III Transcription Termination",0.6288050846834166,0.9614403062839793,23.0,2.0,100312.43478260869,"4781, 171568"]
["Reactome","R-HSA-193639","p75NTR signals via NF-kB",0.6304519249281585,0.9614809942443727,17.0,2.0,123256.05882352941,"4792, 4790"]
["Reactome","R-HSA-8948216","Collagen chain trimerization",0.6332788787252482,0.9614809942443727,47.0,7.0,207506.0,"80781, 1282, 1284, 1277, 1292, 1303, 7373"]
["Reactome","R-HSA-373076","Class A/1 (Rhodopsin-like receptors)",0.6345258252666294,0.9615701311708494,316.0,32.0,143172.2594936709,"1889, 623, 1909, 1910, 2852, 5660, 152, 153, 154, 624, 718, 728, 885, 886, 1236, 1325, 1814, 1902, 2867, 3274, 3357, 3363, 5368, 5734, 5739, 6352, 6363, 6387, 6865, 8620, 122876, 339403"]
["Reactome","R-HSA-5684264","MAP3K8 (TPL2)-dependent MAPK1/3 activation",0.6360833224606186,0.9615701311708494,16.0,2.0,106206.875,"4790, 79155"]
["Reactome","R-HSA-372790","Signaling by GPCR",0.636918083147288,0.9615701311708494,1274.0,113.0,127897.59340659341,"8874, 29, 5575, 1889, 5747, 153090, 109, 115, 623, 818, 1607, 1843, 1909, 1910, 2246, 2852, 3708, 5154, 5295, 5660, 5999, 6196, 7434, 8527, 9693, 9828, 22821, 26686, 27237, 55160, 108, 111, 152, 153, 154, 284, 624, 718, 728, 747, 815, 885, 886, 976, 1236, 1325, 1437, 1814, 1847, 1902, 1956, 2248, 2254, 2255, 2768, 2867, 2906, 3082, 3274, 3357, 3363, 3667, 5136, 5138, 5155, 5159, 5364, 5368, 5536, 5690, 5734, 5739, 5879, 5921, 5996, 5998, 6000, 6003, 6004, 6352, 6363, 6387, 6655, 6865, 7204, 7474, 7477, 8324, 8490, 8503, 8620, 8787, 9048, 9138, 9181, 9965, 10276, 10636, 11214, 11343, 23236, 23263, 26230, 27115, 51332, 53831, 57580, 57731, 59345, 81285, 90226, 122876, 339403"]
["KEGG Pathways","hsa00970","Aminoacyl-tRNA biosynthesis",0.6376684220089504,0.8803820723878223,41.0,4.0,84642.39024390244,"833, 2617, 6301, 79587"]
["Reactome","R-HSA-425393","Transport of inorganic cations/anions and amino acids/oligopeptides",0.6400683358617424,0.963668344103821,105.0,12.0,143300.34285714285,"55117, 6546, 6533, 6560, 6575, 8140, 10723, 23315, 55089, 57030, 83733, 340024"]
["Reactome","R-HSA-379724","tRNA Aminoacylation",0.641022977242259,0.963763335742534,42.0,4.0,88069.78571428571,"833, 2617, 6301, 79587"]
["Reactome","R-HSA-442755","Activation of NMDA receptor upon glutamate binding and postsynaptic events",0.6448439752141726,0.9654796914217737,40.0,6.0,258633.85,"109, 818, 6196, 815, 2893, 2906"]
["Reactome","R-HSA-2151201","Transcriptional activation of mitochondrial biogenesis",0.6504421759694473,0.9679153478380259,45.0,5.0,168297.3111111111,"4209, 211, 4208, 10499, 64784"]
["KEGG Pathways","hsa04310","Wnt signaling pathway",0.6508098125474178,0.883549745511395,150.0,19.0,191688.12666666668,"1488, 4088, 595, 818, 6477, 85409, 815, 1499, 5602, 5879, 6422, 7474, 7477, 8324, 8607, 23236, 23500, 64321, 85407"]
["Reactome","R-HSA-373760","L1CAM interactions",0.652633970711583,0.9679424859847289,118.0,14.0,172012.43220338982,"6196, 23114, 214, 286, 288, 1956, 3678, 3688, 5058, 5879, 8828, 8829, 51332, 57731"]
["Reactome","R-HSA-917937","Iron uptake and transport",0.6555375571095505,0.9679424859847289,44.0,4.0,75046.47727272728,"9114, 30061, 245972, 261729"]
["Reactome","R-HSA-5654738","Signaling by FGFR2",0.6577669332530813,0.9679424859847289,74.0,7.0,136726.4054054054,"2246, 5295, 2248, 2254, 2255, 2549, 3187"]
["Reactome","R-HSA-2142845","Hyaluronan metabolism",0.6628186853382981,0.9679424859847289,16.0,2.0,138198.75,"960, 3074"]
["Reactome","R-HSA-165054","Rev-mediated nuclear export of HIV RNA",0.6664869069893076,0.9679424859847289,33.0,3.0,83823.09090909091,"1104, 23225, 23279"]
["Reactome","R-HSA-109581","Apoptosis",0.6671471914550213,0.9679424859847289,170.0,16.0,124002.45294117647,"5747, 598, 356, 1499, 2934, 4000, 4836, 5690, 6304, 7082, 7186, 7431, 8428, 8737, 8795, 10971"]
["Reactome","R-HSA-977444","GABA B receptor activation",0.6677023531449798,0.9679424859847289,40.0,5.0,186276.45,"109, 115, 108, 111, 3773"]
["Reactome","R-HSA-991365","Activation of GABAB receptors",0.6677023531449798,0.9679424859847289,40.0,5.0,186276.45,"109, 115, 108, 111, 3773"]
["Reactome","R-HSA-72306","tRNA processing",0.668600844769078,0.9679424859847289,106.0,8.0,71634.88679245283,"1787, 10940, 23225, 23279, 60528, 80324, 115708, 152992"]
["Reactome","R-HSA-5576892","Phase 0 - rapid depolarisation",0.6751483145354122,0.9679424859847289,46.0,6.0,186624.95652173914,"818, 779, 781, 782, 815, 9254"]
["KEGG Pathways","hsa00564","Glycerophospholipid metabolism",0.6869514329407986,0.9183863935985515,79.0,8.0,141659.49367088606,"56894, 1607, 8527, 8398, 9489, 10555, 23761, 253558"]
["Reactome","R-HSA-438064","Post NMDA receptor activation events",0.6900528297990947,0.9679424859847289,36.0,5.0,195118.11111111112,"109, 818, 6196, 815, 2906"]
["Reactome","R-HSA-3247509","Chromatin modifying enzymes",0.6901133017996459,0.9679424859847289,270.0,22.0,106264.91481481481,"9612, 595, 84159, 1108, 1788, 4790, 6881, 7468, 8607, 9112, 10499, 23081, 29943, 51317, 54496, 54904, 55904, 57492, 63976, 64754, 79831, 84678"]
["Reactome","R-HSA-4839726","Chromatin organization",0.6901133017996459,0.9679424859847289,270.0,22.0,106264.91481481481,"9612, 595, 84159, 1108, 1788, 4790, 6881, 7468, 8607, 9112, 10499, 23081, 29943, 51317, 54496, 54904, 55904, 57492, 63976, 64754, 79831, 84678"]
["Reactome","R-HSA-421270","Cell-cell junction organization",0.6938799555461812,0.9679424859847289,63.0,8.0,389471.90476190473,"1000, 1007, 1012, 1495, 1499, 5817, 49861, 56288"]
["Reactome","R-HSA-3214842","HDMs demethylate histones",0.697513274483262,0.9679424859847289,49.0,4.0,91693.08163265306,"84159, 23081, 79831, 84678"]
["Reactome","R-HSA-389356","CD28 co-stimulation",0.6979564802177515,0.9679424859847289,33.0,4.0,140901.39393939395,"5295, 5058, 5879, 8503"]
["Reactome","R-HSA-5357801","Programmed Cell Death",0.701570261968838,0.9679424859847289,173.0,16.0,122557.95953757226,"5747, 598, 356, 1499, 2934, 4000, 4836, 5690, 6304, 7082, 7186, 7431, 8428, 8737, 8795, 10971"]
["Reactome","R-HSA-418217","G beta:gamma signalling through PLC beta",0.7024280727749166,0.9679424859847289,20.0,2.0,105260.6,"23236, 59345"]
["KEGG Pathways","hsa04114","Oocyte meiosis",0.7024414219873781,0.9183863935985515,110.0,12.0,145933.43636363637,"109, 115, 818, 3708, 5500, 6196, 108, 111, 815, 3480, 4085, 10971"]
["Reactome","R-HSA-350562","Regulation of ornithine decarboxylase (ODC)",0.7028404978631719,0.9679424859847289,51.0,4.0,67560.1568627451,"51582, 4947, 4953, 5690"]
["Reactome","R-HSA-8866652","Synthesis of active ubiquitin: roles of E1 and E2 enzymes",0.7029186694549043,0.9679424859847289,30.0,3.0,98121.63333333333,"997, 7328, 7874"]
["Reactome","R-HSA-381340","Transcriptional regulation of white adipocyte differentiation",0.7057885799477779,0.9679424859847289,86.0,9.0,158727.2093023256,"1879, 7026, 9612, 51586, 948, 4790, 5346, 10499, 23389"]
["KEGG Pathways","hsa04621","NOD-like receptor signaling pathway",0.7062118213942661,0.9183863935985515,58.0,6.0,114313.29310344828,"4792, 3553, 4790, 5602, 6352, 7128"]
["Reactome","R-HSA-2142691","Synthesis of Leukotrienes (LT) and Eoxins (EX)",0.7078427455093348,0.9679424859847289,22.0,2.0,64574.86363636364,"4048, 4363"]
["KEGG Pathways","hsa00532","Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",0.7108013628708244,0.9183863935985515,22.0,3.0,194956.0909090909,"22856, 166012, 337876"]
["KEGG Pathways","hsa04660","T cell receptor signaling pathway",0.7113498484236911,0.9183863935985515,108.0,12.0,130830.99074074074,"4792, 5295, 8440, 1437, 1493, 2353, 3937, 4790, 5058, 6655, 8503, 10892"]
["KEGG Pathways","hsa00533","Glycosaminoglycan biosynthesis - keratan sulfate",0.7123094467422911,0.9183863935985515,15.0,2.0,169568.53333333333,"6482, 6487"]
["Reactome","R-HSA-381676","Glucagon-like Peptide-1 (GLP1) regulates insulin secretion",0.713263581274539,0.9679424859847289,42.0,5.0,139700.38095238095,"5575, 3708, 111, 26251, 59345"]
["Reactome","R-HSA-196757","Metabolism of folate and pterines",0.7143925596456797,0.9679424859847289,17.0,2.0,113311.58823529411,"10840, 25902"]
["Reactome","R-HSA-1222556","ROS, RNS production in phagocytes",0.7159248230043858,0.9679424859847289,33.0,3.0,83026.69696969698,"4688, 9114, 245972"]
["Reactome","R-HSA-177243","Interactions of Rev with host cellular proteins",0.7186856507381443,0.9679424859847289,35.0,3.0,80914.4857142857,"1104, 23225, 23279"]
["Reactome","R-HSA-382551","Transmembrane transport of small molecules",0.7191012655897799,0.9679424859847289,675.0,64.0,129721.65037037036,"5575, 358, 55117, 109, 115, 818, 861, 3098, 6546, 108, 111, 362, 477, 486, 488, 489, 815, 845, 2039, 2569, 2570, 3101, 4308, 4363, 5205, 5243, 5690, 6518, 6526, 6533, 6536, 6560, 6575, 6588, 7442, 8140, 8737, 8989, 9114, 9123, 10723, 11059, 22841, 23225, 23279, 23315, 23327, 23678, 30061, 53373, 54795, 55089, 56606, 57030, 57194, 59345, 80036, 80727, 83733, 121601, 219931, 245972, 261729, 340024"]
["KEGG Pathways","hsa04710","Circadian rhythm",0.7319878580309298,0.9285469066549737,22.0,3.0,197643.0909090909,"8553, 4862, 6096"]
["Reactome","R-HSA-72202","Transport of Mature Transcript to Cytoplasm",0.7390547829737313,0.9679424859847289,82.0,6.0,68302.70731707317,"6430, 10212, 10250, 23225, 23279, 84248"]
["Reactome","R-HSA-2980766","Nuclear Envelope Breakdown",0.7398883067408536,0.9679424859847289,51.0,5.0,127750.88235294117,"4000, 7444, 10783, 23225, 23279"]
["Reactome","R-HSA-4086398","Ca2+ pathway",0.7413187446299521,0.9679424859847289,60.0,7.0,155875.71666666667,"3708, 815, 1499, 7474, 23112, 23236, 59345"]
["Reactome","R-HSA-69231","Cyclin D associated events in G1",0.7432838439279097,0.9679424859847289,39.0,4.0,105440.35897435897,"595, 1021, 1027, 5520"]
["Reactome","R-HSA-69236","G1 Phase",0.7432838439279097,0.9679424859847289,39.0,4.0,105440.35897435897,"595, 1021, 1027, 5520"]
["Reactome","R-HSA-427389","ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression",0.7449604806969587,0.9679424859847289,71.0,3.0,25933.140845070422,"1108, 2074, 9112"]
["Reactome","R-HSA-917729","Endosomal Sorting Complex Required For Transport (ESCRT)",0.7453356614124187,0.9679424859847289,28.0,2.0,47072.75,"9146, 11267"]
["Reactome","R-HSA-397795","G-protein beta:gamma signalling",0.7479428499153813,0.9679424859847289,51.0,5.0,115937.64705882352,"5295, 1437, 8503, 23236, 59345"]
["Reactome","R-HSA-193807","Synthesis of bile acids and bile salts via 27-hydroxycholesterol",0.750714802562199,0.9679424859847289,15.0,2.0,140638.4,"5740, 10499"]
["Reactome","R-HSA-8866910","TFAP2 (AP-2) family regulates transcription of growth factors and their receptors",0.7599223833902475,0.9679424859847289,15.0,2.0,193113.46666666667,"1956, 2099"]
["KEGG Pathways","hsa00360","Phenylalanine metabolism",0.7599249172584593,0.9320732889049409,17.0,2.0,130436.41176470589,"220, 8639"]
["KEGG Pathways","hsa00760","Nicotinate and nicotinamide metabolism",0.7631422752976045,0.9320732889049409,24.0,3.0,155554.54166666666,"23057, 23475, 56953"]
["Reactome","R-HSA-2559582","Senescence-Associated Secretory Phenotype (SASP)",0.7634952474933077,0.9679424859847289,104.0,6.0,71463.01923076923,"3490, 6196, 1021, 1027, 2353, 4790"]
["Reactome","R-HSA-190828","Gap junction trafficking",0.7651834231090685,0.9679424859847289,46.0,4.0,90821.08695652174,"2701, 10052, 84694, 219770"]
["Reactome","R-HSA-380108","Chemokine receptors bind chemokines",0.7658984487926916,0.9679424859847289,48.0,4.0,75719.02083333333,"1236, 6352, 6363, 6387"]
["Reactome","R-HSA-5654727","Negative regulation of FGFR2 signaling",0.7686510059036047,0.9679424859847289,34.0,4.0,203499.67647058822,"2246, 2248, 2254, 2255"]
["Reactome","R-HSA-72187","mRNA 3'-end processing",0.7708042828537862,0.9679424859847289,59.0,4.0,58449.64406779661,"6430, 10212, 10250, 84248"]
["Reactome","R-HSA-3781865","Diseases of glycosylation",0.7716568104068384,0.9679424859847289,78.0,10.0,219267.14102564103,"7058, 9509, 6383, 7057, 9508, 10417, 54437, 79875, 170690, 170691"]
["KEGG Pathways","hsa00670","One carbon pool by folate",0.771739022749981,0.9320732889049409,18.0,2.0,92882.5,"10840, 25902"]
["Reactome","R-HSA-391160","Signal regulatory protein (SIRP) family interactions",0.7740569294062613,0.9679424859847289,16.0,2.0,126226.3125,"5747, 8935"]
["KEGG Pathways","hsa00260","Glycine, serine and threonine metabolism",0.7774855239158287,0.9320732889049409,32.0,3.0,101007.71875,"1491, 211, 8639"]
["Reactome","R-HSA-977443","GABA receptor activation",0.785085688063494,0.9679424859847289,56.0,7.0,204268.5357142857,"109, 115, 108, 111, 2569, 2570, 3773"]
["KEGG Pathways","hsa04975","Fat digestion and absorption",0.7901642196046585,0.9362369766293241,45.0,4.0,155476.73333333334,"948, 4547, 8398, 10555"]
["Reactome","R-HSA-379726","Mitochondrial tRNA aminoacylation",0.7980162815210187,0.9679424859847289,21.0,2.0,91890.76190476191,"2617, 79587"]
["Reactome","R-HSA-15869","Metabolism of nucleotides",0.8018804573941316,0.9679424859847289,96.0,8.0,85803.08333333333,"2766, 204, 956, 1635, 7378, 51733, 56953, 122622"]
["Reactome","R-HSA-5696397","Gap-filling DNA repair synthesis and ligation in GG-NER",0.8081266970412491,0.9679424859847289,25.0,2.0,70818.16,"51426, 56655"]
["Reactome","R-HSA-2187338","Visual phototransduction",0.8082582362534172,0.9679424859847289,96.0,9.0,128011.29166666667,"4836, 6383, 7804, 8787, 9227, 29967, 64220, 131890, 157506"]
["Reactome","R-HSA-3301854","Nuclear Pore Complex (NPC) Disassembly",0.8091739142594019,0.9679424859847289,34.0,3.0,93051.88235294117,"10783, 23225, 23279"]
["Reactome","R-HSA-73780","RNA Polymerase III Chain Elongation",0.8126465324415981,0.9679424859847289,18.0,1.0,34804.055555555555,"171568"]
["KEGG Pathways","hsa03022","Basal transcription factors",0.8177362044912371,0.9470956040717718,35.0,3.0,67517.4,"2957, 6873, 6881"]
["Reactome","R-HSA-5693565","Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",0.8198496303889884,0.9679424859847289,74.0,5.0,67657.28378378379,"2139, 2138, 5536, 7336, 7468"]
["Reactome","R-HSA-500657","Presynaptic function of Kainate receptors",0.8316033182188071,0.9679424859847289,21.0,2.0,116396.95238095238,"23236, 59345"]
["Reactome","R-HSA-69273","Cyclin A/B1 associated events during G2/M transition",0.8385452583462606,0.9679424859847289,22.0,2.0,91777.27272727272,"5520, 7465"]
["Reactome","R-HSA-936440","Negative regulators of RIG-I/MDA5 signaling",0.8388805271477964,0.9679424859847289,36.0,3.0,75428.77777777778,"1540, 7128, 84166"]
["Reactome","R-HSA-3772470","Negative regulation of TCF-dependent signaling by WNT ligand antagonists",0.8407833672405625,0.9679424859847289,15.0,2.0,188011.33333333334,"6422, 7474"]
["Reactome","R-HSA-5693606","DNA Double Strand Break Response",0.8463621018873808,0.9679424859847289,75.0,5.0,67477.96,"2139, 2138, 5536, 7336, 7468"]
["Reactome","R-HSA-2029485","Role of phospholipids in phagocytosis",0.8537639591339565,0.9679424859847289,26.0,3.0,175010.57692307694,"3708, 5295, 8398"]
["Reactome","R-HSA-111885","Opioid Signalling",0.8538661443699895,0.9679424859847289,83.0,9.0,196350.07228915664,"5575, 109, 115, 3708, 108, 111, 5136, 23236, 59345"]
["Reactome","R-HSA-3769402","Deactivation of the beta-catenin transactivating complex",0.8607646547327911,0.9679424859847289,42.0,5.0,249509.30952380953,"9580, 1499, 7090, 64321, 283149"]
["Reactome","R-HSA-211897","Cytochrome P450 - arranged by substrate type",0.861463628699097,0.9679424859847289,65.0,6.0,101641.32307692307,"5447, 196, 1545, 5740, 9915, 10499"]
["Reactome","R-HSA-428157","Sphingolipid metabolism",0.8621209223865672,0.9679424859847289,87.0,8.0,125236.89655172414,"2581, 5660, 2760, 3074, 6609, 8877, 23683, 57488"]
["Reactome","R-HSA-5339562","Uptake and actions of bacterial toxins",0.8688406511085355,0.9679424859847289,30.0,3.0,152822.46666666667,"928, 5606, 5608"]
["Reactome","R-HSA-5620922","BBSome-mediated cargo-targeting to cilium",0.8706549086211974,0.9679424859847289,23.0,2.0,96469.34782608696,"6950, 10694"]
["Reactome","R-HSA-6804115","TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain",0.8749973292650887,0.9679424859847289,21.0,2.0,104888.42857142857,"4850, 10769"]
["Reactome","R-HSA-196807","Nicotinate metabolism",0.875963606549437,0.9679424859847289,29.0,3.0,140417.10344827586,"5740, 23057, 23475"]
["Reactome","R-HSA-425366","Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds",0.8763531012582925,0.9679424859847289,104.0,10.0,163637.83653846153,"55117, 861, 6518, 6526, 6533, 6536, 9123, 30061, 56606, 340024"]
["Reactome","R-HSA-5654704","SHC-mediated cascade:FGFR3",0.8767875443090228,0.9679424859847289,18.0,2.0,137317.22222222222,"2246, 2254"]
["Reactome","R-HSA-2173796","SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",0.8768566877622659,0.9679424859847289,33.0,3.0,96717.69696969698,"4088, 4092, 3726"]
["Reactome","R-HSA-445989","TAK1 activates NFkB by phosphorylation and activation of IKKs complex",0.8793450863027488,0.9679424859847289,33.0,3.0,124793.66666666667,"4792, 4790, 6285"]
["Reactome","R-HSA-6806667","Metabolism of fat-soluble vitamins",0.8818553134181206,0.9679424859847289,50.0,5.0,171997.44,"6383, 7804, 8029, 9227, 29967"]
["Reactome","R-HSA-69618","Mitotic Spindle Checkpoint",0.8893699260019265,0.9679424859847289,20.0,2.0,127850.7,"8379, 4085"]
["Reactome","R-HSA-381771","Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",0.8895196820381227,0.9679424859847289,20.0,2.0,132802.15,"1499, 1803"]
["Reactome","R-HSA-4085001","Sialic acid metabolism",0.8906777071933399,0.9679424859847289,33.0,4.0,194739.45454545456,"6482, 6487, 7903, 256435"]
["KEGG Pathways","hsa04370","VEGF signaling pathway",0.8932679905833323,0.9776847930658017,75.0,7.0,126488.45333333334,"5747, 5295, 5879, 7867, 8398, 8503, 8877"]
["Reactome","R-HSA-3214858","RMTs methylate histone arginines",0.8958490151101638,0.9679424859847289,73.0,4.0,86198.28767123287,"595, 1788, 54496, 57492"]
["Reactome","R-HSA-3371556","Cellular response to heat stress",0.8995089054192545,0.9679424859847289,89.0,7.0,83612.73033707865,"818, 57521, 815, 3308, 10049, 23225, 23279"]
["Reactome","R-HSA-211981","Xenobiotics",0.9001832767846641,0.9679424859847289,22.0,2.0,92455.63636363637,"196, 9915"]
["Reactome","R-HSA-1638074","Keratan sulfate/keratin metabolism",0.9016290621682108,0.9679424859847289,32.0,3.0,118197.90625,"3074, 6482, 6487"]
["KEGG Pathways","hsa00600","Sphingolipid metabolism",0.9021178383140238,0.9776847930658017,40.0,4.0,146757.8,"2581, 6609, 8877, 9514"]
["Reactome","R-HSA-70614","Amino acid synthesis and interconversion (transamination)",0.9030386412223139,0.9679424859847289,30.0,3.0,166961.1,"4942, 256987, 374569"]
["Reactome","R-HSA-159418","Recycling of bile acids and salts",0.905319530511141,0.9679424859847289,16.0,2.0,147333.25,"2172, 10499"]
["KEGG Pathways","hsa04666","Fc gamma R-mediated phagocytosis",0.9074037727588589,0.9776847930658017,94.0,10.0,157415.86170212767,"5295, 1794, 2934, 4651, 5058, 5879, 8398, 8503, 8853, 8877"]
["Reactome","R-HSA-975634","Retinoid metabolism and transport",0.9146168228122017,0.9679424859847289,42.0,4.0,177678.42857142858,"6383, 7804, 9227, 29967"]
["Reactome","R-HSA-73762","RNA Polymerase I Transcription Initiation",0.9162896645555528,0.9679424859847289,48.0,3.0,57999.708333333336,"1108, 2074, 9112"]
["Reactome","R-HSA-2514859","Inactivation, recovery and regulation of the phototransduction cascade",0.9215949741681856,0.9679424859847289,33.0,3.0,94662.24242424243,"4836, 8787, 131890"]
["Reactome","R-HSA-5576886","Phase 4 - resting membrane potential",0.9273442018534489,0.9679424859847289,19.0,2.0,189267.47368421053,"3777, 51305"]
["Reactome","R-HSA-5654741","Signaling by FGFR3",0.9300503308879492,0.9679424859847289,40.0,4.0,181754.9,"2246, 5295, 2254, 2549"]
["Reactome","R-HSA-5654733","Negative regulation of FGFR4 signaling",0.9313600885965898,0.9679424859847289,31.0,3.0,174106.7741935484,"2246, 2254, 9965"]
["Reactome","R-HSA-77387","Insulin receptor recycling",0.9463501042394602,0.9780157387025395,27.0,2.0,73483.55555555556,"9114, 245972"]
["KEGG Pathways","hsa04962","Vasopressin-regulated water reabsorption",0.9466263243426839,0.9776847930658017,44.0,4.0,127749.29545454546,"109, 115, 9586, 10540"]
["KEGG Pathways","hsa00230","Purine metabolism",0.9576156983637482,0.9776847930658017,161.0,15.0,137619.4099378882,"109, 115, 2766, 108, 111, 204, 956, 5136, 5138, 10201, 27115, 56655, 56953, 122622, 171568"]
["KEGG Pathways","hsa00250","Alanine, aspartate and glutamate metabolism",0.9591732299429009,0.9776847930658017,32.0,3.0,127398.34375,"8659, 8528, 122622"]
["Reactome","R-HSA-2514856","The phototransduction cascade",0.9611137653924662,0.9893949036742585,34.0,3.0,93930.70588235294,"4836, 8787, 131890"]
["Reactome","R-HSA-3214815","HDACs deacetylate histones",0.96330101891917,0.9893949036742585,88.0,4.0,53475.14772727273,"9612, 1108, 9112, 51317"]
["Reactome","R-HSA-109688","Cleavage of Growing Transcript in the Termination Region ",0.9661345979587397,0.9893949036742585,68.0,4.0,55754.16176470588,"6430, 10212, 10250, 84248"]
["Reactome","R-HSA-73856","RNA Polymerase II Transcription Termination",0.9661345979587397,0.9893949036742585,68.0,4.0,55754.16176470588,"6430, 10212, 10250, 84248"]
["Reactome","R-HSA-6802957","Oncogenic MAPK signaling",0.9672753050257725,0.9893949036742585,76.0,8.0,144585.51315789475,"23164, 153090, 22821, 22906, 4000, 5921, 9444, 23499"]
["Reactome","R-HSA-429947","Deadenylation of mRNA",0.9674286893466154,0.9893949036742585,22.0,2.0,96120.09090909091,"4850, 255967"]
["KEGG Pathways","hsa04976","Bile secretion",0.9713528245610648,0.9809228031281688,71.0,8.0,163770.45070422534,"358, 109, 115, 108, 111, 477, 486, 5243"]
["Reactome","R-HSA-1912408","Pre-NOTCH Transcription and Translation",0.9733094273155382,0.9933996238541223,30.0,3.0,115624.0,"55534, 595, 23112"]
["Reactome","R-HSA-6784531","tRNA processing in the nucleus",0.974770503660468,0.9933996238541223,58.0,4.0,74093.24137931035,"10940, 23225, 23279, 60528"]
["Reactome","R-HSA-429914","Deadenylation-dependent mRNA decay",0.975677405508028,0.9933996238541223,53.0,4.0,74901.71698113208,"4850, 27258, 196513, 255967"]
["Reactome","R-HSA-5607764","CLEC7A (Dectin-1) signaling",0.9759925669847134,0.9933996238541223,99.0,8.0,96351.23232323233,"3708, 4792, 997, 3553, 4790, 5690, 10892, 64581"]
["Reactome","R-HSA-1483166","Synthesis of PA",0.9895637286400086,0.9958181359357222,33.0,3.0,177433.78787878787,"56894, 10555, 253558"]
["Reactome","R-HSA-451326","Activation of Kainate Receptors upon glutamate binding",0.9902110352997998,0.9958181359357222,31.0,3.0,196665.0,"23236, 59345, 83988"]
["Reactome","R-HSA-167161","HIV Transcription Initiation",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["Reactome","R-HSA-167162","RNA Polymerase II HIV Promoter Escape",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["Reactome","R-HSA-73776","RNA Polymerase II Promoter Escape",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["Reactome","R-HSA-73779","RNA Polymerase II Transcription Pre-Initiation And Promoter Opening",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["Reactome","R-HSA-75953","RNA Polymerase II Transcription Initiation",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["Reactome","R-HSA-76042","RNA Polymerase II Transcription Initiation And Promoter Clearance",0.9939757342041111,0.9958181359357222,47.0,3.0,64110.8085106383,"2957, 6873, 6881"]
["KEGG Pathways","hsa00310","Lysine degradation",0.9959799374495548,0.9959799374495548,44.0,4.0,128293.13636363637,"219, 7468, 8424, 54904"]
["Reactome","R-HSA-174800","Chylomicron-mediated lipid transport",0.998347783995237,0.998347783995237,26.0,2.0,125942.65384615384,"5046, 4547"]
["KEGG Pathways","hsa04740","Olfactory transduction",2.803374444126801E-4,0.007183647013074927,380.0,5.0,60744.70789473684,"109, 818, 26686, 815, 81285"]
["Reactome","R-HSA-381753","Olfactory Signaling Pathway",5.619818999306223E-4,0.10753044853035987,377.0,2.0,54966.572944297084,"26686, 81285"]
["Reactome","R-HSA-74160","Gene Expression",0.007049580517321965,0.278166471952178,1771.0,102.0,88937.48842461886,"4088, 9612, 51586, 55534, 80139, 677, 2908, 4092, 6122, 6497, 28996, 51422, 57521, 220988, 833, 1027, 1108, 1787, 1788, 1820, 1956, 2074, 2099, 2353, 2617, 2957, 3164, 3187, 3622, 3726, 4781, 4809, 4850, 4878, 4929, 5305, 5520, 5608, 5690, 5914, 5976, 6096, 6123, 6159, 6301, 6430, 6627, 6746, 6794, 6873, 6881, 7003, 7004, 7005, 7067, 7247, 7728, 7874, 8664, 8795, 8892, 9099, 9112, 9891, 10002, 10212, 10250, 10413, 10499, 10643, 10769, 10772, 10940, 10971, 11066, 23112, 23225, 23279, 23327, 23405, 25879, 26173, 27258, 30832, 55226, 58490, 60528, 79047, 79587, 79664, 80324, 84248, 85403, 115708, 130916, 143689, 144348, 144455, 152992, 171568, 196513, 255967"]
["Reactome","R-HSA-5617833","Cilium Assembly",0.010055861383688029,0.31680542484364793,202.0,6.0,91509.82178217822,"84131, 3797, 6950, 10540, 10694, 54806"]
["Reactome","R-HSA-392499","Metabolism of proteins",0.013713762879008386,0.3447576202839085,1577.0,99.0,115333.12428662016,"4088, 55647, 2137, 3091, 3624, 4092, 4792, 6122, 6477, 7058, 9509, 55031, 83696, 197257, 152, 154, 249, 286, 288, 966, 997, 1499, 1509, 1540, 1636, 1803, 2099, 2590, 2934, 4000, 4045, 4248, 4249, 4878, 5201, 5624, 5690, 6000, 6123, 6159, 6482, 6487, 6672, 6746, 6881, 6904, 6950, 7057, 7128, 7186, 7328, 7709, 7874, 7903, 8607, 8664, 8737, 8787, 8877, 8892, 9099, 9112, 9114, 9146, 9508, 9804, 9960, 10318, 10417, 10540, 10600, 10694, 10890, 22955, 23225, 23279, 23621, 50863, 51255, 51332, 54437, 57731, 59345, 63971, 64284, 79155, 79875, 83746, 84909, 114803, 116138, 117248, 146712, 170690, 170691, 221937, 253827, 256435, 349633"]
["Reactome","R-HSA-1428517","The citric acid (TCA) cycle and respiratory electron transport",0.016449972881219365,0.358855930656245,155.0,2.0,70198.8,"5164, 9123"]
["Reactome","R-HSA-446203","Asparagine N-linked glycosylation",0.017053910583940953,0.36147602629882686,299.0,13.0,130608.07692307692,"83696, 286, 288, 966, 4248, 4249, 6482, 6487, 7903, 10540, 51332, 57731, 256435"]
["KEGG Pathways","hsa04141","Protein processing in endoplasmic reticulum",0.018594632256029194,0.1815190291659993,165.0,5.0,110940.97575757575,"5602, 6746, 7186, 10277, 64374"]
["Reactome","R-HSA-212436","Generic Transcription Pathway",0.020169111952456596,0.3900884331473856,845.0,50.0,104480.83195266272,"4088, 9612, 51586, 55534, 80139, 2908, 4092, 6497, 28996, 51422, 57521, 1027, 1108, 1820, 1956, 2099, 2353, 3164, 3622, 3726, 4850, 4878, 4929, 5305, 5608, 5914, 6096, 6794, 6873, 6881, 7003, 7004, 7005, 7067, 7728, 7874, 8795, 9099, 9891, 10002, 10413, 10499, 10769, 10971, 23112, 23327, 30832, 79047, 144348, 144455"]
["Reactome","R-HSA-1852241","Organelle biogenesis and maintenance",0.024666222877753056,0.4102182604746316,348.0,15.0,90098.9827586207,"4209, 51253, 51422, 84131, 211, 3797, 4208, 6950, 10499, 10540, 10694, 51649, 54806, 64784, 64983"]
["Reactome","R-HSA-597592","Post-translational protein modification",0.02574815782327361,0.42172361525695107,1026.0,66.0,130478.00194931774,"4088, 55647, 3091, 4092, 4792, 7058, 9509, 55031, 83696, 154, 249, 286, 288, 966, 997, 1540, 2099, 2590, 4045, 4248, 4249, 5624, 5690, 6482, 6487, 6672, 6881, 7057, 7128, 7186, 7328, 7874, 7903, 8607, 8737, 9099, 9112, 9146, 9508, 9804, 9960, 10318, 10417, 10540, 10600, 10890, 22955, 23225, 23279, 50863, 51255, 51332, 54437, 57731, 64284, 79155, 79875, 83746, 114803, 117248, 146712, 170690, 170691, 221937, 256435, 349633"]
["KEGG Pathways","hsa05012","Parkinson's disease",0.03085636244021249,0.2635647625101483,114.0,1.0,77591.83333333333,"84701"]
["KEGG Pathways","hsa05016","Huntington's disease",0.04217917488371331,0.2879583505149121,174.0,6.0,90800.08620689655,"3708, 627, 9586, 10540, 23236, 84701"]
["Reactome","R-HSA-156580","Phase II conjugation",0.04262682244795737,0.5340498825263964,104.0,2.0,92459.93269230769,"2948, 2950"]
["Reactome","R-HSA-6811434","COPI-dependent Golgi-to-ER retrograde traffic",0.04670116296503178,0.5547687600571358,97.0,2.0,103959.9175257732,"1062, 3797"]
["Reactome","R-HSA-69481","G2/M Checkpoints",0.06832684117636836,0.620683321946674,167.0,5.0,67430.2634730539,"5690, 7336, 7465, 7468, 10971"]
["Reactome","R-HSA-1638091","Heparan sulfate/heparin (HS-GAG) metabolism",0.07020114231629818,0.6323952903659861,55.0,2.0,293822.7090909091,"3340, 6383"]
["Reactome","R-HSA-5632684","Hedgehog 'on' state",0.07161092143791117,0.6362276326911962,85.0,2.0,97851.5411764706,"2736, 5690"]
["Reactome","R-HSA-3214847","HATs acetylate histones",0.07541464231703283,0.6386855745647371,138.0,3.0,59532.8768115942,"6881, 8607, 10499"]
["Reactome","R-HSA-5620912","Anchoring of the basal body to the plasma membrane",0.07563757293292028,0.6386855745647371,98.0,3.0,88115.60204081633,"84131, 10540, 54806"]
["Reactome","R-HSA-382556","ABC-family proteins mediated transport",0.07818103833022506,0.6386855745647371,105.0,3.0,98164.14285714286,"4363, 5243, 5690"]
["Reactome","R-HSA-1640170","Cell Cycle",0.07821856192786178,0.6386855745647371,622.0,36.0,98474.94372990353,"23353, 8379, 23345, 595, 1859, 5500, 22822, 84131, 84962, 1021, 1027, 1062, 4000, 4085, 5520, 5690, 7336, 7444, 7465, 7468, 8556, 8607, 10540, 10783, 10844, 10971, 23141, 23225, 23279, 23310, 27030, 55839, 55920, 56655, 79648, 147841"]
["Reactome","R-HSA-112310","Neurotransmitter Release Cycle",0.08151758706128233,0.6479449383326926,50.0,1.0,169070.66,"57030"]
["Reactome","R-HSA-2467813","Separation of Sister Chromatids",0.08432021175085201,0.6601685290048475,183.0,8.0,99866.4480874317,"8379, 1062, 4085, 5690, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-5693538","Homology Directed Repair",0.09221595548541348,0.6601685290048475,136.0,4.0,74921.80147058824,"7336, 7468, 51426, 56655"]
["KEGG Pathways","hsa00190","Oxidative phosphorylation",0.09303707502271155,0.4146217473838232,116.0,3.0,63725.80172413793,"9114, 84701, 245972"]
["Reactome","R-HSA-69306","DNA Replication",0.09648429599774459,0.6679942261280594,108.0,3.0,87094.50925925926,"1027, 5690, 56655"]
["Reactome","R-HSA-5619115","Disorders of transmembrane transporters",0.09835824003703618,0.6679942261280594,75.0,1.0,89492.89333333333,"5690"]
["KEGG Pathways","hsa00140","Steroid hormone biosynthesis",0.09866660092564107,0.43035432318630684,55.0,1.0,93307.21818181819,"1545"]
["Reactome","R-HSA-5693607","Processing of DNA double-strand break ends",0.1003761677944181,0.6736601059969112,97.0,2.0,65649.30927835051,"7336, 7468"]
["Reactome","R-HSA-69278","Cell Cycle, Mitotic",0.1014889032950548,0.6736601059969112,517.0,29.0,95195.33849129594,"8379, 595, 1859, 5500, 22822, 84131, 84962, 1021, 1027, 1062, 4000, 4085, 5520, 5690, 7444, 7465, 8556, 10540, 10783, 10844, 23141, 23225, 23279, 23310, 55839, 55920, 56655, 79648, 147841"]
["Reactome","R-HSA-450531","Regulation of mRNA stability by proteins that bind AU-rich elements",0.10162309683291858,0.6736601059969112,87.0,2.0,77020.85057471265,"677, 5690"]
["Reactome","R-HSA-6791226","Major pathway of rRNA processing in the nucleolus and cytosol",0.1026662396629452,0.6736601059969112,172.0,5.0,62972.61627906977,"6122, 4809, 6123, 6159, 25879"]
["Reactome","R-HSA-68874","M/G1 Transition",0.10431798242837721,0.675091009410871,85.0,2.0,92327.38823529411,"5690, 56655"]
["Reactome","R-HSA-69002","DNA Replication Pre-Initiation",0.10431798242837721,0.675091009410871,85.0,2.0,92327.38823529411,"5690, 56655"]
["Reactome","R-HSA-6811442","Intra-Golgi and retrograde Golgi-to-ER traffic",0.10706236388003083,0.6788420129170247,193.0,10.0,116642.11917098446,"56894, 1062, 1523, 2590, 3797, 8398, 8675, 10540, 10618, 23299"]
["Reactome","R-HSA-8852276","The role of GTSE1 in G2/M progression after G2 checkpoint",0.11105408910745618,0.6840274234993214,77.0,1.0,56449.01298701299,"5690"]
["Reactome","R-HSA-69620","Cell Cycle Checkpoints",0.11412700116161936,0.6840274234993214,198.0,8.0,74931.39393939394,"8379, 1027, 4085, 5690, 7336, 7465, 7468, 10971"]
["Reactome","R-HSA-5693567","HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)",0.11552203418309778,0.6840274234993214,130.0,4.0,74057.74615384615,"7336, 7468, 51426, 56655"]
["Reactome","R-HSA-948021","Transport to the Golgi and subsequent modification",0.11568485172828029,0.6840274234993214,180.0,9.0,113854.45,"83696, 286, 288, 966, 4248, 4249, 10540, 51332, 57731"]
["Reactome","R-HSA-73894","DNA Repair",0.11587468842307704,0.6840274234993214,312.0,15.0,81383.05128205128,"2139, 2138, 2074, 5536, 7336, 7468, 7874, 8607, 10920, 23583, 51426, 56655, 79068, 79840, 199990"]
["Reactome","R-HSA-174178","APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1",0.11827247302662564,0.6840274234993214,71.0,1.0,62853.281690140844,"5690"]
["Reactome","R-HSA-5610785","GLI3 is processed to GLI3R by the proteasome",0.12042908529282265,0.6840274234993214,60.0,1.0,85211.26666666666,"5690"]
["Reactome","R-HSA-68867","Assembly of the pre-replicative complex",0.1221592802679812,0.6840274234993214,68.0,1.0,65194.92647058824,"5690"]
["Reactome","R-HSA-983169","Class I MHC mediated antigen processing & presentation",0.12255340911214395,0.6840274234993214,368.0,23.0,114818.73913043478,"79754, 6477, 948, 997, 4008, 4688, 5690, 7328, 7336, 10324, 11059, 23327, 51665, 55182, 57542, 63893, 80176, 114907, 127544, 136371, 140691, 283807, 390594"]
["Reactome","R-HSA-75105","Fatty Acyl-CoA Biosynthesis",0.12282476009525604,0.6840274234993214,53.0,1.0,119482.58490566038,"9524"]
["Reactome","R-HSA-8854518","AURKA Activation by TPX2",0.12405907787569467,0.6840274234993214,73.0,2.0,82512.87671232877,"84131, 10540"]
["Reactome","R-HSA-5619084","ABC transporter disorders",0.12726831314443757,0.6840274234993214,68.0,1.0,89371.07352941176,"5690"]
["Reactome","R-HSA-204005","COPII (Coat Protein 2) Mediated Vesicle Transport",0.12786513167097932,0.6840274234993214,70.0,2.0,98709.82857142857,"83696, 966"]
["Reactome","R-HSA-380270","Recruitment of mitotic centrosome proteins and complexes",0.12826490872027993,0.6840274234993214,93.0,3.0,76494.95698924731,"84131, 10540, 10844"]
["Reactome","R-HSA-380287","Centrosome maturation",0.12826490872027993,0.6840274234993214,93.0,3.0,76494.95698924731,"84131, 10540, 10844"]
["Reactome","R-HSA-437239","Recycling pathway of L1",0.1291513517455795,0.6840274234993214,47.0,1.0,122830.65957446808,"6196"]
["Reactome","R-HSA-176408","Regulation of APC/C activators between G1/S and early anaphase",0.12949639709113175,0.6840274234993214,79.0,2.0,77820.46835443038,"4085, 5690"]
["Reactome","R-HSA-174154","APC/C:Cdc20 mediated degradation of Securin",0.12975568230257267,0.6840274234993214,66.0,1.0,65676.39393939394,"5690"]
["Reactome","R-HSA-380259","Loss of Nlp from mitotic centrosomes",0.1325233681833253,0.6840274234993214,70.0,2.0,84814.24285714286,"84131, 10540"]
["Reactome","R-HSA-380284","Loss of proteins required for interphase microtubule organization from the centrosome",0.1325233681833253,0.6840274234993214,70.0,2.0,84814.24285714286,"84131, 10540"]
["Reactome","R-HSA-5610780","Degradation of GLI1 by the proteasome",0.13482863672523604,0.6840274234993214,60.0,1.0,72507.0,"5690"]
["KEGG Pathways","hsa04742","Taste transduction",0.13533104347531416,0.5273371875366437,51.0,1.0,129011.58823529411,"5136"]
["KEGG Pathways","hsa00830","Retinol metabolism",0.13633595580215668,0.5273371875366437,63.0,2.0,90707.8253968254,"9227, 157506"]
["Reactome","R-HSA-453274","Mitotic G2-G2/M phases",0.13793177800393885,0.6840274234993214,194.0,9.0,80869.86082474227,"5500, 22822, 84131, 84962, 5520, 5690, 7465, 10540, 10844"]
["Reactome","R-HSA-5620924","Intraflagellar transport",0.13794997574942444,0.6840274234993214,54.0,1.0,81747.46296296296,"3797"]
["Reactome","R-HSA-212165","Epigenetic regulation of gene expression",0.13803758557286042,0.6840274234993214,145.0,4.0,63886.262068965516,"1108, 1788, 2074, 9112"]
["Reactome","R-HSA-69242","S Phase",0.14128900468969796,0.6840274234993214,129.0,5.0,79962.0,"595, 1027, 5690, 7465, 56655"]
["Reactome","R-HSA-72662","Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S",0.14299677001899608,0.6840274234993214,59.0,1.0,79561.49152542373,"8664"]
["Reactome","R-HSA-174084","Autodegradation of Cdh1 by Cdh1:APC/C",0.14789866622948508,0.6840274234993214,62.0,1.0,65663.82258064517,"5690"]
["Reactome","R-HSA-69239","Synthesis of DNA",0.1482236760156278,0.6840274234993214,100.0,3.0,70926.37,"1027, 5690, 56655"]
["Reactome","R-HSA-1236974","ER-Phagosome pathway",0.14830481754847846,0.6840274234993214,83.0,2.0,73399.63855421687,"948, 5690"]
["Reactome","R-HSA-5663205","Infectious disease",0.14840583408374272,0.6840274234993214,379.0,19.0,80068.89709762533,"928, 6122, 1104, 1499, 1794, 2957, 4836, 5606, 5608, 5690, 5879, 6123, 6159, 6873, 6881, 9146, 23225, 23279, 23327"]
["Reactome","R-HSA-72649","Translation initiation complex formation",0.148476740644139,0.6840274234993214,58.0,1.0,79736.4827586207,"8664"]
["Reactome","R-HSA-69275","G2/M Transition",0.1486427624491655,0.6840274234993214,192.0,9.0,80749.66666666667,"5500, 22822, 84131, 84962, 5520, 5690, 7465, 10540, 10844"]
["Reactome","R-HSA-1236975","Antigen processing-Cross presentation",0.1488426335792906,0.6840274234993214,99.0,3.0,74657.25252525252,"948, 4688, 5690"]
["Reactome","R-HSA-68886","M Phase",0.1499137714647633,0.6840274234993214,317.0,16.0,92375.91482649843,"8379, 1062, 4000, 4085, 5520, 5690, 7444, 10783, 23141, 23225, 23279, 23310, 55839, 55920, 79648, 147841"]
["Reactome","R-HSA-72702","Ribosomal scanning and start codon recognition",0.15095736588578743,0.6840274234993214,58.0,1.0,78839.13793103448,"8664"]
["Reactome","R-HSA-5607761","Dectin-1 mediated noncanonical NF-kB signaling",0.1513120144268236,0.6840274234993214,60.0,1.0,68994.63333333333,"5690"]
["Reactome","R-HSA-5633008","TP53 Regulates Transcription of Cell Death Genes",0.15142170453963227,0.6840274234993214,45.0,1.0,112444.95555555556,"8795"]
["Reactome","R-HSA-201681","TCF dependent signaling in response to WNT",0.15215197872180483,0.6840274234993214,226.0,12.0,116619.18584070797,"9580, 857, 1499, 5690, 6422, 7090, 7474, 8607, 64321, 84133, 283149, 440193"]
["Reactome","R-HSA-8868773","rRNA processing in the nucleus and cytosol",0.15252149313520463,0.6840274234993214,183.0,6.0,61017.174863387976,"6122, 4809, 6123, 6159, 25879, 55226"]
["Reactome","R-HSA-5676590","NIK-->noncanonical NF-kB signaling",0.15488146019758578,0.6840274234993214,59.0,1.0,69604.77966101695,"5690"]
["Reactome","R-HSA-176814","Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins",0.15589075416622108,0.6840274234993214,75.0,2.0,76772.49333333333,"4085, 5690"]
["Reactome","R-HSA-5685942","HDR through Homologous Recombination (HRR)",0.15606400491994624,0.6840274234993214,67.0,2.0,94061.28358208956,"51426, 56655"]
["Reactome","R-HSA-5678895","Defective CFTR causes cystic fibrosis",0.15726526810740762,0.6840274234993214,61.0,1.0,93511.01639344262,"5690"]
["Reactome","R-HSA-68827","CDT1 association with the CDC6:ORC:origin complex",0.15955471290810247,0.6840274234993214,59.0,1.0,66816.08474576271,"5690"]
["Reactome","R-HSA-176409","APC/C:Cdc20 mediated degradation of mitotic proteins",0.16010105236033814,0.6840274234993214,74.0,2.0,77322.58108108108,"4085, 5690"]
["Reactome","R-HSA-3700989","Transcriptional Regulation by TP53",0.1605105234837517,0.6840274234993214,365.0,22.0,95431.74520547946,"28996, 51422, 57521, 1027, 1108, 1820, 2353, 3622, 4850, 5305, 5608, 6794, 6873, 6881, 7874, 8795, 9099, 9891, 10769, 10971, 23112, 144455"]
["Reactome","R-HSA-4641257","Degradation of AXIN",0.16072429747347608,0.6840274234993214,55.0,1.0,76724.70909090909,"5690"]
["Reactome","R-HSA-6796648","TP53 Regulates Transcription of DNA Repair Genes",0.161497194590145,0.6846214405958696,66.0,1.0,55766.28787878788,"2353"]
["Reactome","R-HSA-4641258","Degradation of DVL",0.1666580991823571,0.6917462854526109,57.0,1.0,69559.78947368421,"5690"]
["Reactome","R-HSA-983189","Kinesins",0.16771978922880837,0.6917462854526109,58.0,2.0,126080.22413793103,"1062, 3797"]
["Reactome","R-HSA-179419","APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint",0.16829719988347516,0.6917462854526109,72.0,2.0,78573.13888888889,"4085, 5690"]
["Reactome","R-HSA-5387390","Hh mutants abrogate ligand secretion",0.17381617974785993,0.6994459558879632,58.0,1.0,96855.6551724138,"5690"]
["Reactome","R-HSA-2559586","DNA Damage/Telomere Stress Induced Senescence",0.1739980624675741,0.6994459558879632,75.0,1.0,58021.88,"1027"]
["Reactome","R-HSA-69206","G1/S Transition",0.1746266344788418,0.6994459558879632,118.0,5.0,96154.66949152542,"595, 1027, 5690, 7465, 56655"]
["KEGG Pathways","hsa01100","Metabolic pathways",0.17530950057778188,0.5905815729243087,1105.0,84.0,124704.47239819005,"3632, 220, 8659, 56894, 32, 1491, 1607, 2137, 2581, 3098, 3705, 3707, 8527, 8871, 60490, 204, 211, 219, 249, 586, 1635, 1787, 1788, 2134, 2235, 2590, 2595, 2632, 2651, 3074, 3101, 3340, 4048, 4248, 4249, 4942, 4953, 5091, 5214, 5224, 5333, 5740, 6482, 6487, 6609, 7299, 7378, 8310, 8398, 8566, 8639, 8877, 9114, 9489, 9514, 9563, 10201, 10555, 11343, 22856, 23057, 23236, 23475, 23761, 25902, 51196, 51733, 54963, 56655, 56953, 64087, 80146, 80201, 84532, 84701, 117248, 122622, 146664, 157506, 171568, 245972, 253558, 256435, 337876"]
["Reactome","R-HSA-69541","Stabilization of p53",0.1760200544186142,0.6994459558879632,55.0,1.0,70116.4909090909,"5690"]
["KEGG Pathways","hsa04146","Peroxisome",0.1786149147380836,0.5905815729243087,78.0,3.0,103381.01282051283,"5828, 8310, 8528"]
["Reactome","R-HSA-169911","Regulation of Apoptosis",0.17886545644637944,0.6994459558879632,53.0,1.0,74686.98113207547,"5690"]
["Reactome","R-HSA-8854050","FBXL7 down-regulates AURKA during mitotic entry and in early mitosis",0.17914114472347253,0.6994459558879632,55.0,1.0,73335.47272727273,"5690"]
["Reactome","R-HSA-174184","Cdc20:Phospho-APC/C mediated degradation of Cyclin A",0.1794518345352584,0.6994459558879632,71.0,2.0,77872.07042253521,"4085, 5690"]
["Reactome","R-HSA-163125","Post-translational modification: synthesis of GPI-anchored proteins",0.17970265966659746,0.6994459558879632,91.0,4.0,191194.5934065934,"249, 4045, 50863, 349633"]
["Reactome","R-HSA-5362768","Hh mutants that don't undergo autocatalytic processing are degraded by ERAD",0.18243252419892605,0.6994459558879632,56.0,1.0,99096.05357142857,"5690"]
["Reactome","R-HSA-168254","Influenza Infection",0.1830030372628775,0.6994459558879632,153.0,5.0,61220.75816993464,"6122, 6123, 6159, 23225, 23279"]
["Reactome","R-HSA-2132295","MHC class II antigen presentation",0.18326885019385725,0.6994459558879632,118.0,5.0,89734.34745762713,"1062, 1508, 1509, 3797, 10540"]
["Reactome","R-HSA-450408","AUF1 (hnRNP D0) binds and destabilizes mRNA",0.18362428160604974,0.6994459558879632,55.0,1.0,70212.25454545455,"5690"]
["Reactome","R-HSA-174113","SCF-beta-TrCP mediated degradation of Emi1",0.18434311447036356,0.6994459558879632,55.0,1.0,65829.2,"5690"]
["Reactome","R-HSA-199977","ER to Golgi Anterograde Transport",0.18558891671639624,0.6994459558879632,149.0,7.0,90098.63087248322,"83696, 286, 288, 966, 10540, 51332, 57731"]
["Reactome","R-HSA-69304","Regulation of DNA replication",0.1865379096702621,0.6994459558879632,76.0,2.0,63811.85526315789,"1027, 5690"]
["Reactome","R-HSA-6803157","Antimicrobial peptides",0.18838535369525547,0.6994459558879632,87.0,2.0,50635.29885057471,"1113, 5657"]
["Reactome","R-HSA-912446","Meiotic recombination",0.18934885559361392,0.6994459558879632,82.0,1.0,45410.08536585366,"27030"]
["Reactome","R-HSA-72695","Formation of the ternary complex, and subsequently, the 43S complex",0.1893862732825103,0.6994459558879632,52.0,1.0,79876.11538461539,"8664"]
["Reactome","R-HSA-162906","HIV Infection",0.1901588412925177,0.6994459558879632,231.0,11.0,78327.05194805194,"1104, 1794, 2957, 4836, 5690, 5879, 6873, 6881, 23225, 23279, 23327"]
["Reactome","R-HSA-112316","Neuronal System",0.1928993741362837,0.7044737278423063,344.0,32.0,257547.56104651163,"22941, 109, 115, 818, 3741, 6196, 23136, 108, 111, 782, 815, 2569, 2570, 2893, 2906, 3773, 3777, 3779, 3782, 7881, 9132, 9254, 10052, 10611, 22871, 23236, 26251, 51305, 57030, 59345, 83988, 84694"]
["Reactome","R-HSA-5696395","Formation of Incision Complex in GG-NER",0.19602285847126685,0.7073302647812787,43.0,1.0,94815.58139534884,"7336"]
["KEGG Pathways","hsa02010","ABC transporters",0.19821191381981343,0.6188761425509766,44.0,2.0,128866.95454545454,"4363, 5243"]
["Reactome","R-HSA-349425","Autodegradation of the E3 ubiquitin ligase COP1",0.20014947777496456,0.7138669234176895,52.0,1.0,69767.86538461539,"5690"]
["Reactome","R-HSA-180585","Vif-mediated degradation of APOBEC3G",0.20372951028593742,0.7138669234176895,54.0,1.0,62411.18518518518,"5690"]
["Reactome","R-HSA-1483257","Phospholipid metabolism",0.20564820282260063,0.7138669234176895,202.0,13.0,127069.599009901,"55697, 56894, 114879, 5295, 8871, 5305, 8398, 8503, 9489, 10555, 11343, 23761, 253558"]
["Reactome","R-HSA-69601","Ubiquitin Mediated Degradation of Phosphorylated Cdc25A",0.2082021758279285,0.7138669234176895,53.0,1.0,63258.50943396227,"5690"]
["Reactome","R-HSA-69610","p53-Independent DNA Damage Response",0.2082021758279285,0.7138669234176895,53.0,1.0,63258.50943396227,"5690"]
["Reactome","R-HSA-69613","p53-Independent G1/S DNA damage checkpoint",0.2082021758279285,0.7138669234176895,53.0,1.0,63258.50943396227,"5690"]
["Reactome","R-HSA-1236978","Cross-presentation of soluble exogenous antigens (endosomes)",0.2110094185171772,0.7138669234176895,50.0,1.0,68012.94,"5690"]
["Reactome","R-HSA-73886","Chromosome Maintenance",0.21112454154986204,0.7138669234176895,104.0,3.0,77597.0,"8607, 55839, 56655"]
["Reactome","R-HSA-69300","Removal of licensing factors from origins",0.21117802150157133,0.7138669234176895,73.0,2.0,63387.27397260274,"1027, 5690"]
["Reactome","R-HSA-174143","APC/C-mediated degradation of cell cycle proteins",0.21318853299342566,0.7138669234176895,85.0,3.0,76477.44705882353,"4085, 5690, 8556"]
["Reactome","R-HSA-453276","Regulation of mitotic cell cycle",0.21318853299342566,0.7138669234176895,85.0,3.0,76477.44705882353,"4085, 5690, 8556"]
["Reactome","R-HSA-180534","Vpu mediated degradation of CD4",0.21424513357321623,0.7138669234176895,52.0,1.0,63806.730769230766,"5690"]
["Reactome","R-HSA-112315","Transmission across Chemical Synapses",0.21460808515899393,0.7138669234176895,213.0,18.0,200396.87323943662,"109, 115, 818, 6196, 108, 111, 782, 815, 2569, 2570, 2893, 2906, 3773, 9254, 23236, 57030, 59345, 83988"]
["Reactome","R-HSA-1630316","Glycosaminoglycan metabolism",0.21871836707687198,0.7208370573478616,124.0,9.0,211176.4193548387,"960, 3074, 3340, 6383, 6482, 6487, 22856, 166012, 337876"]
["Reactome","R-HSA-5250924","B-WICH complex positively regulates rRNA expression",0.21998141461531479,0.7227960765931771,88.0,1.0,29243.147727272728,"2074"]
["Reactome","R-HSA-5628897","TP53 Regulates Metabolic Genes",0.2210412101580603,0.7240774187298885,83.0,4.0,107887.39759036145,"51422, 57521, 10971, 23112"]
["Reactome","R-HSA-112382","Formation of RNA Pol II elongation complex ",0.22737712919887476,0.7266380112014625,62.0,1.0,46010.66129032258,"85403"]
["Reactome","R-HSA-75955","RNA Polymerase II Transcription Elongation",0.22737712919887476,0.7266380112014625,62.0,1.0,46010.66129032258,"85403"]
["Reactome","R-HSA-8854214","TBC/RABGAPs",0.22751711489939472,0.7266380112014625,45.0,1.0,71068.53333333334,"2844"]
["KEGG Pathways","hsa03008","Ribosome biogenesis in eukaryotes",0.22787179868737062,0.6770104163900141,74.0,3.0,84398.52702702703,"4809, 10940, 55226"]
["Reactome","R-HSA-68877","Mitotic Prometaphase",0.22970534637352655,0.7266380112014625,128.0,7.0,118781.625,"8379, 1062, 4085, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-68949","Orc1 removal from chromatin",0.2307478087663928,0.7266380112014625,71.0,2.0,63110.126760563384,"1027, 5690"]
["Reactome","R-HSA-69052","Switching of origins to a post-replicative state",0.2307478087663928,0.7266380112014625,71.0,2.0,63110.126760563384,"1027, 5690"]
["Reactome","R-HSA-211733","Regulation of activated PAK-2p34 by proteasome mediated degradation",0.23498324334098278,0.7278543016266544,50.0,1.0,62814.58,"5690"]
["Reactome","R-HSA-72766","Translation",0.2351107312478783,0.7278543016266544,156.0,6.0,61507.6858974359,"6122, 6123, 6159, 6746, 8664, 8892"]
["Reactome","R-HSA-2565942","Regulation of PLK1 Activity at G2/M Transition",0.23566050468948108,0.7278543016266544,88.0,4.0,88270.96590909091,"5500, 84131, 84962, 10540"]
["Reactome","R-HSA-69017","CDK-mediated phosphorylation and removal of Cdc6",0.23696587609706102,0.7298008890624585,51.0,1.0,61008.35294117647,"5690"]
["Reactome","R-HSA-983168","Antigen processing: Ubiquitination & Proteasome degradation",0.24014209198296813,0.7333152582869733,306.0,21.0,121834.00326797385,"79754, 6477, 997, 4008, 5690, 7328, 7336, 10324, 11059, 23327, 51665, 55182, 57542, 63893, 80176, 114907, 127544, 136371, 140691, 283807, 390594"]
["Reactome","R-HSA-5610783","Degradation of GLI2 by the proteasome",0.24171213205580697,0.7339629627874363,60.0,2.0,81340.45,"2736, 5690"]
["Reactome","R-HSA-1971475","A tetrasaccharide linker sequence is required for GAG synthesis",0.2444810011146327,0.7399395690176367,26.0,1.0,261631.53846153847,"6383"]
["KEGG Pathways","hsa04730","Long-term depression",0.2452585208997219,0.6931778471911263,69.0,5.0,251200.08695652173,"3708, 2768, 3480, 8398, 23236"]
["KEGG Pathways","hsa03050","Proteasome",0.24731430534105306,0.6931778471911263,43.0,1.0,70546.69767441861,"5690"]
["Reactome","R-HSA-5578749","Transcriptional regulation by small RNAs",0.24744201412961633,0.7422556489278626,100.0,2.0,43637.08,"23225, 23279"]
["Reactome","R-HSA-2022928","HS-GAG biosynthesis",0.24920317195197847,0.7422556489278626,31.0,2.0,385715.06451612903,"3340, 6383"]
["Reactome","R-HSA-5358346","Hedgehog ligand biogenesis",0.24979985819675324,0.7422556489278626,65.0,2.0,111594.4,"5690, 6868"]
["Reactome","R-HSA-114452","Activation of BH3-only proteins",0.24994008476039395,0.7422556489278626,31.0,1.0,120084.45161290323,"10971"]
["KEGG Pathways","hsa00982","Drug metabolism - cytochrome P450",0.25022029605923585,0.6931778471911263,72.0,3.0,74444.65277777778,"220, 2948, 2950"]
["Reactome","R-HSA-168255","Influenza Life Cycle",0.25041420489688687,0.7422556489278626,142.0,5.0,62061.64788732395,"6122, 6123, 6159, 23225, 23279"]
["Reactome","R-HSA-4086400","PCP/CE pathway",0.25177494278936086,0.7422556489278626,92.0,4.0,95913.28260869565,"5690, 5879, 7474, 8324"]
["Reactome","R-HSA-5620920","Cargo trafficking to the periciliary membrane",0.2519961361299959,0.7422556489278626,52.0,2.0,110223.98076923077,"6950, 10694"]
["Reactome","R-HSA-75109","Triglyceride Biosynthesis",0.2542452780774608,0.7465699862620758,78.0,4.0,127251.83333333333,"56894, 9524, 10555, 253558"]
["Reactome","R-HSA-6794362","Protein-protein interactions at synapses",0.2548869832456755,0.7465699862620758,71.0,6.0,446937.5211267606,"22941, 23136, 2893, 2906, 10611, 22871"]
["Reactome","R-HSA-195253","Degradation of beta-catenin by the destruction complex",0.25605944871589686,0.7465699862620758,82.0,4.0,131789.73170731709,"1488, 1499, 5690, 7090"]
["Reactome","R-HSA-392518","Signal amplification",0.2589072041493862,0.7512529406659851,33.0,1.0,153504.9090909091,"59345"]
["Reactome","R-HSA-69615","G1/S DNA Damage Checkpoints",0.2592204873898358,0.7512529406659851,66.0,2.0,66581.40909090909,"1027, 5690"]
["Reactome","R-HSA-1296065","Inwardly rectifying K+ channels",0.2603420580884969,0.7518185574070476,31.0,1.0,155828.38709677418,"3773"]
["Reactome","R-HSA-5693532","DNA Double-Strand Break Repair",0.261127282258863,0.7518185574070476,164.0,8.0,84654.18902439025,"2139, 2138, 5536, 7336, 7468, 51426, 56655, 79840"]
["KEGG Pathways","hsa00565","Ether lipid metabolism",0.2618015910625538,0.7155910155709804,35.0,1.0,143982.0285714286,"8398"]
["Reactome","R-HSA-195721","Signaling by Wnt",0.2622121127788447,0.7518601960581728,323.0,21.0,118199.13003095976,"1488, 3708, 9580, 815, 857, 1499, 5690, 5879, 6422, 7090, 7474, 7477, 8324, 8607, 23112, 23236, 59345, 64321, 84133, 283149, 440193"]
["Reactome","R-HSA-432720","Lysosome Vesicle Biogenesis",0.2648775686674681,0.7574937876442672,36.0,1.0,109150.41666666667,"9146"]
["Reactome","R-HSA-8856688","Golgi-to-ER retrograde transport",0.2678584143136627,0.7581762820374476,125.0,7.0,122338.952,"56894, 1062, 2590, 3797, 8398, 10540, 23299"]
["Reactome","R-HSA-162909","Host Interactions of HIV factors",0.26869402921825636,0.7581762820374476,131.0,6.0,77489.06870229008,"1104, 1794, 5690, 5879, 23225, 23279"]
["Reactome","R-HSA-446193","Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",0.26928469445579145,0.7581762820374476,78.0,4.0,178231.53846153847,"6482, 6487, 7903, 256435"]
["Reactome","R-HSA-69563","p53-Dependent G1 DNA Damage Response",0.2768540243188071,0.763994201177694,64.0,2.0,67231.625,"1027, 5690"]
["Reactome","R-HSA-69580","p53-Dependent G1/S DNA damage checkpoint",0.2768540243188071,0.763994201177694,64.0,2.0,67231.625,"1027, 5690"]
["Reactome","R-HSA-5683826","Surfactant metabolism",0.2770450757277114,0.763994201177694,30.0,1.0,128384.36666666667,"152"]
["KEGG Pathways","hsa00380","Tryptophan metabolism",0.27996632457564663,0.7238720894642333,42.0,2.0,138174.2142857143,"219, 1545"]
["Reactome","R-HSA-6805567","Keratinization",0.2859410127901133,0.7683749104905647,212.0,6.0,36435.72169811321,"5046, 3713, 3892, 23254, 112802, 353137"]
["Reactome","R-HSA-163841","Gamma carboxylation, hypusine formation and arylsulfatase activation",0.2875524860031555,0.7683749104905647,38.0,1.0,141704.7894736842,"5624"]
["Reactome","R-HSA-1660661","Sphingolipid de novo biosynthesis",0.2898045658530333,0.7683749104905647,43.0,2.0,126587.09302325582,"8877, 23683"]
["Reactome","R-HSA-5358351","Signaling by Hedgehog",0.2900171450314198,0.7683749104905647,149.0,9.0,128041.61744966442,"5575, 109, 115, 108, 111, 2736, 5690, 6868, 27152"]
["Reactome","R-HSA-5694530","Cargo concentration in the ER",0.2902075786337639,0.7683749104905647,34.0,1.0,104011.32352941176,"966"]
["Reactome","R-HSA-6783310","Fanconi Anemia Pathway",0.2928355935264734,0.7702074856499216,38.0,1.0,77808.42105263157,"199990"]
["KEGG Pathways","hsa00020","Citrate cycle (TCA cycle)",0.29455342487175223,0.7238720894642333,30.0,1.0,169309.73333333334,"5091"]
["KEGG Pathways","hsa00650","Butanoate metabolism",0.2953873686255584,0.7238720894642333,30.0,1.0,124548.63333333333,"65985"]
["KEGG Pathways","hsa04120","Ubiquitin mediated proteolysis",0.296785256582727,0.7238720894642333,134.0,10.0,144012.78358208956,"11060, 6477, 997, 4214, 7328, 10277, 11059, 23327, 51366, 63893"]
["KEGG Pathways","hsa00040","Pentose and glucuronate interconversions",0.2971500879901139,0.7238720894642333,32.0,1.0,78882.09375,"219"]
["Reactome","R-HSA-212300","PRC2 methylates histones and DNA",0.29930686599412154,0.77926027897641,68.0,1.0,44940.220588235294,"1788"]
["Reactome","R-HSA-2426168","Activation of gene expression by SREBF (SREBP)",0.30068063236094106,0.77926027897641,42.0,2.0,148480.2857142857,"32, 10499"]
["Reactome","R-HSA-2500257","Resolution of Sister Chromatid Cohesion",0.3013235861351891,0.77926027897641,120.0,7.0,117338.25833333333,"8379, 1062, 4085, 23279, 55839, 55920, 147841"]
["KEGG Pathways","hsa00514","Other types of O-glycan biosynthesis",0.30284663376745247,0.7238720894642333,46.0,2.0,103487.15217391304,"6487, 146664"]
["KEGG Pathways","hsa04950","Maturity onset diabetes of the young",0.3030293884328745,0.7238720894642333,24.0,1.0,184604.5,"389692"]
["Reactome","R-HSA-1483255","PI Metabolism",0.30428995182153806,0.785053551119529,78.0,5.0,138988.28205128206,"55697, 5295, 8871, 5305, 8503"]
["Reactome","R-HSA-2990846","SUMOylation",0.30550468528481795,0.7863108685544957,108.0,6.0,102277.52777777778,"6672, 9112, 22955, 23225, 23279, 83746"]
["Reactome","R-HSA-68962","Activation of the pre-replicative complex",0.30936538569757466,0.7913787547197283,32.0,1.0,140091.5625,"56655"]
["Reactome","R-HSA-199991","Membrane Trafficking",0.30954262207534766,0.7913787547197283,622.0,48.0,120560.05466237942,"23216, 56894, 6272, 8871, 51422, 51429, 83696, 154, 286, 288, 966, 1062, 1523, 1956, 2590, 2701, 2844, 3267, 3797, 4621, 5879, 6764, 7082, 7164, 7474, 8301, 8398, 8675, 9026, 9146, 9698, 10052, 10540, 10618, 10890, 10920, 10971, 11267, 22898, 23258, 23299, 26258, 51332, 54453, 57731, 84694, 90019, 219770"]
["Reactome","R-HSA-72706","GTP hydrolysis and joining of the 60S ribosomal subunit",0.30966994749902416,0.7913787547197283,112.0,4.0,59897.357142857145,"6122, 6123, 6159, 8664"]
["KEGG Pathways","hsa05322","Systemic lupus erythematosus",0.3107353359651343,0.7238720894642333,126.0,4.0,48259.96031746032,"87, 81, 718, 958"]
["Reactome","R-HSA-3560782","Diseases associated with glycosaminoglycan metabolism",0.3112539450273506,0.7935507419211463,25.0,1.0,209582.64,"6383"]
["Reactome","R-HSA-1799339","SRP-dependent cotranslational protein targeting to membrane",0.31413484080209036,0.796233593871341,112.0,4.0,59712.642857142855,"6122, 6123, 6159, 6746"]
["Reactome","R-HSA-72312","rRNA processing",0.31494244374702574,0.796233593871341,193.0,8.0,62335.538860103625,"6122, 4809, 6123, 6159, 25879, 55226, 60528, 130916"]
["Reactome","R-HSA-1655829","Regulation of cholesterol biosynthesis by SREBP (SREBF)",0.3150764729773802,0.796233593871341,55.0,3.0,138974.5090909091,"32, 10499, 22937"]
["Reactome","R-HSA-156827","L13a-mediated translational silencing of Ceruloplasmin expression",0.3159890950701251,0.796233593871341,111.0,4.0,60336.55855855856,"6122, 6123, 6159, 8664"]
["Reactome","R-HSA-5689603","UCH proteinases",0.3174684917107853,0.7981010221845555,99.0,4.0,73444.53535353535,"4092, 5690, 8607, 221937"]
["Reactome","R-HSA-6794361","Interactions of neurexins and neuroligins at synapses",0.3214903981301588,0.8044701860618094,57.0,5.0,429363.2807017544,"22941, 23136, 2906, 10611, 22871"]
["Reactome","R-HSA-4791275","Signaling by WNT in cancer",0.32283604457537857,0.8059717417690168,34.0,2.0,184078.82352941178,"1488, 1499"]
["Reactome","R-HSA-210500","Glutamate Neurotransmitter Release Cycle",0.32648614178545016,0.8061876527888009,24.0,1.0,190377.79166666666,"57030"]
["Reactome","R-HSA-6811438","Intra-Golgi traffic",0.3287996037427142,0.8061876527888009,44.0,2.0,116731.65909090909,"1523, 8675"]
["Reactome","R-HSA-168273","Influenza Viral RNA Transcription and Replication",0.32899341330739473,0.8061876527888009,133.0,5.0,62059.47368421053,"6122, 6123, 6159, 23225, 23279"]
["Reactome","R-HSA-72163","mRNA Splicing - Major Pathway",0.32963454443353374,0.8061876527888009,184.0,8.0,67719.71195652174,"220988, 3187, 4809, 6430, 6627, 10250, 10772, 27258"]
["Reactome","R-HSA-157579","Telomere Maintenance",0.3327616162163266,0.8100188543559214,77.0,2.0,63481.03896103896,"8607, 56655"]
["KEGG Pathways","hsa04612","Antigen processing and presentation",0.33318179534986736,0.7589140894080312,68.0,2.0,45372.867647058825,"1508, 3308"]
["Reactome","R-HSA-504046","RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription",0.33419834324027836,0.8100188543559214,144.0,5.0,58173.131944444445,"1108, 2074, 4781, 9112, 171568"]
["Reactome","R-HSA-453279","Mitotic G1-G1/S phases",0.33743929191328825,0.816044462099026,142.0,8.0,97438.1690140845,"595, 1859, 1021, 1027, 5520, 5690, 7465, 56655"]
["KEGG Pathways","hsa03015","mRNA surveillance pathway",0.3430217969378373,0.7727414106841389,82.0,5.0,143255.48780487804,"5520, 5522, 5976, 10250, 124540"]
["Reactome","R-HSA-3108214","SUMOylation of DNA damage response and repair proteins",0.34412093660642573,0.8188322065188307,77.0,4.0,91691.74025974025,"6672, 22955, 23225, 23279"]
["Reactome","R-HSA-1500620","Meiosis",0.34628086131182495,0.819101993606308,115.0,4.0,70352.17391304347,"23353, 23345, 4000, 27030"]
["Reactome","R-HSA-2024096","HS-GAG degradation",0.3473719311044344,0.8198887718862305,22.0,1.0,235670.54545454544,"6383"]
["Reactome","R-HSA-72764","Eukaryotic Translation Termination",0.3506583672470416,0.8220310126304863,93.0,3.0,56865.87096774193,"6122, 6123, 6159"]
["Reactome","R-HSA-2555396","Mitotic Metaphase and Anaphase",0.35099340038418453,0.8220310126304863,195.0,12.0,107804.70256410257,"8379, 1062, 4000, 4085, 5520, 5690, 7444, 23141, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-202040","G-protein activation",0.3553939038310463,0.8227523351295869,29.0,1.0,96942.62068965517,"59345"]
["Reactome","R-HSA-2980736","Peptide hormone metabolism",0.35558913503327383,0.8227523351295869,90.0,6.0,163534.8111111111,"3624, 1499, 1509, 1636, 1803, 84909"]
["KEGG Pathways","hsa05340","Primary immunodeficiency",0.35633402197260644,0.7889005301145489,35.0,1.0,109844.31428571428,"958"]
["Reactome","R-HSA-1296041","Activation of G protein gated Potassium channels",0.3567820140572598,0.8227523351295869,25.0,1.0,172987.2,"3773"]
["Reactome","R-HSA-1296059","G protein gated Potassium channels",0.3567820140572598,0.8227523351295869,25.0,1.0,172987.2,"3773"]
["Reactome","R-HSA-997272","Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits",0.3567820140572598,0.8227523351295869,25.0,1.0,172987.2,"3773"]
["Reactome","R-HSA-71406","Pyruvate metabolism and Citric Acid (TCA) cycle",0.35747366703500044,0.8227523351295869,48.0,2.0,85891.66666666667,"5164, 9123"]
["KEGG Pathways","hsa03010","Ribosome",0.3578914600031856,0.7889005301145489,88.0,3.0,56009.09090909091,"6122, 6123, 6159"]
["Reactome","R-HSA-75876","Synthesis of very long-chain fatty acyl-CoAs",0.35993544272254685,0.822958491559215,27.0,1.0,156857.40740740742,"9524"]
["KEGG Pathways","hsa04672","Intestinal immune network for IgA production",0.3632007001641479,0.7920866333367056,46.0,2.0,87086.04347826086,"958, 6387"]
["Reactome","R-HSA-112387","Elongation arrest and recovery",0.3638710445723531,0.8258728131284899,50.0,1.0,37802.34,"85403"]
["Reactome","R-HSA-68882","Mitotic Anaphase",0.3657220598060085,0.8258728131284899,194.0,12.0,107709.55154639175,"8379, 1062, 4000, 4085, 5520, 5690, 7444, 23141, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-186712","Regulation of beta-cell development",0.3659107001190046,0.8258728131284899,32.0,2.0,195360.34375,"2255, 389692"]
["Reactome","R-HSA-69473","G2/M DNA damage checkpoint",0.3691892674206864,0.8297164201284034,94.0,4.0,69474.01063829787,"7336, 7465, 7468, 10971"]
["Reactome","R-HSA-6811440","Retrograde transport at the Trans-Golgi-Network",0.3700456262129346,0.8299156056767267,48.0,2.0,78074.54166666667,"8675, 10618"]
["Reactome","R-HSA-8873719","RAB geranylgeranylation",0.37480333045839975,0.8340009262803821,64.0,3.0,87806.40625,"55647, 10890, 64284"]
["Reactome","R-HSA-180024","DARPP-32 events",0.37851764251022124,0.8357640590919769,25.0,1.0,179717.84,"5575"]
["Reactome","R-HSA-420092","Glucagon-type ligand receptors",0.37938225971103273,0.8357640590919769,30.0,1.0,77450.33333333333,"59345"]
["Reactome","R-HSA-5368287","Mitochondrial translation",0.3798923958914272,0.8357640590919769,92.0,3.0,50487.30434782609,"51253, 51649, 64983"]
["Reactome","R-HSA-418592","ADP signalling through P2Y purinoceptor 1",0.3805277821034726,0.8357640590919769,25.0,1.0,175803.48,"59345"]
["KEGG Pathways","hsa03420","Nucleotide excision repair",0.380594576242201,0.8062424983400798,44.0,2.0,126611.29545454546,"2074, 56655"]
["Reactome","R-HSA-73893","DNA Damage Bypass",0.38373096029838805,0.8397027693978897,50.0,2.0,77139.28,"51426, 56655"]
["KEGG Pathways","hsa04140","Regulation of autophagy",0.38540356591132874,0.8062424983400798,34.0,1.0,67372.20588235294,"84971"]
["Reactome","R-HSA-399956","CRMPs in Sema3A signaling",0.3871826334362348,0.8421417037114082,16.0,1.0,304708.3125,"8829"]
["Reactome","R-HSA-8866654","E3 ubiquitin ligases ubiquitinate target proteins",0.38811050180364576,0.8424647639553033,42.0,1.0,56375.95238095238,"51255"]
["KEGG Pathways","hsa00591","Linoleic acid metabolism",0.38935613334472147,0.8062424983400798,28.0,1.0,135594.85714285713,"8398"]
["Reactome","R-HSA-3108232","SUMO E3 ligases SUMOylate target proteins",0.391708702232558,0.8468742142267903,102.0,6.0,102713.75490196078,"6672, 9112, 22955, 23225, 23279, 83746"]
["Reactome","R-HSA-156842","Eukaryotic Translation Elongation",0.39454537083633456,0.8496086571196766,93.0,3.0,53574.17204301075,"6122, 6123, 6159"]
["Reactome","R-HSA-2408522","Selenoamino acid metabolism",0.4013229776337578,0.8527283277010309,116.0,5.0,70819.74137931035,"1491, 6122, 6123, 6159, 6301"]
["Reactome","R-HSA-192823","Viral mRNA Translation",0.40204981899208764,0.8527283277010309,89.0,3.0,56345.988764044945,"6122, 6123, 6159"]
["Reactome","R-HSA-1614635","Sulfur amino acid metabolism",0.4031607949778491,0.8527283277010309,25.0,1.0,119797.84,"1491"]
["Reactome","R-HSA-8855121","VLDL interactions",0.4034789442272176,0.8527283277010309,22.0,1.0,222826.54545454544,"4547"]
["Reactome","R-HSA-6802949","Signaling by RAS mutants",0.40422895389220487,0.8527283277010309,51.0,3.0,118197.90196078431,"153090, 22821, 5921"]
["Reactome","R-HSA-1368082","RORA activates gene expression",0.4046346155279093,0.8527283277010309,28.0,2.0,274400.14285714284,"4862, 10499"]
["Reactome","R-HSA-3560783","Defective B4GALT7 causes EDS, progeroid type",0.40686183454584873,0.8527283277010309,19.0,1.0,256897.47368421053,"6383"]
["Reactome","R-HSA-3560801","Defective B3GAT3 causes JDSSDHD",0.40686183454584873,0.8527283277010309,19.0,1.0,256897.47368421053,"6383"]
["Reactome","R-HSA-4420332","Defective B3GALT6 causes EDSP2 and SEMDJL1",0.40686183454584873,0.8527283277010309,19.0,1.0,256897.47368421053,"6383"]
["Reactome","R-HSA-4608870","Asymmetric localization of PCP proteins",0.40887765970850043,0.8532158176370986,65.0,3.0,95224.10769230769,"5690, 7474, 8324"]
["Reactome","R-HSA-425410","Metal ion SLC transporters",0.41489392110167694,0.8532158176370986,25.0,1.0,162667.28,"30061"]
["Reactome","R-HSA-110314","Recognition of DNA damage by PCNA-containing replication complex",0.4151217926713728,0.8532158176370986,30.0,1.0,75235.6,"56655"]
["Reactome","R-HSA-4641263","Regulation of FZD by ubiquitination",0.416110480627573,0.8532158176370986,21.0,1.0,148229.09523809524,"84133"]
["Reactome","R-HSA-76046","RNA Polymerase III Transcription Initiation",0.4165254805748801,0.8532158176370986,36.0,1.0,55914.75,"171568"]
["Reactome","R-HSA-72172","mRNA Splicing",0.4166514111121936,0.8532158176370986,192.0,9.0,67700.88541666667,"220988, 3187, 4809, 6430, 6627, 10250, 10772, 11066, 27258"]
["Reactome","R-HSA-156902","Peptide chain elongation",0.41859368409434355,0.8549330292029931,89.0,3.0,55288.93258426966,"6122, 6123, 6159"]
["Reactome","R-HSA-389513","CTLA4 inhibitory signaling",0.41925360947942036,0.8549330292029931,22.0,1.0,111739.72727272728,"1493"]
["Reactome","R-HSA-373080","Class B/2 (Secretin family receptors)",0.42211471537170275,0.8549330292029931,91.0,6.0,112348.84615384616,"976, 7474, 7477, 8324, 59345, 90226"]
["Reactome","R-HSA-1483206","Glycerophospholipid biosynthesis",0.4221833941968092,0.8549330292029931,125.0,8.0,119334.888,"56894, 114879, 8398, 9489, 10555, 11343, 23761, 253558"]
["Reactome","R-HSA-6783589","Interleukin-6 family signaling",0.42858449045229036,0.8595544233375249,27.0,1.0,81261.14814814815,"6772"]
["KEGG Pathways","hsa04940","Type I diabetes mellitus",0.4296940160853001,0.8388229351479163,41.0,2.0,83112.90243902439,"356, 3553"]
["Reactome","R-HSA-416993","Trafficking of GluR2-containing AMPA receptors",0.42990903851097473,0.8606142048710439,16.0,1.0,325816.1875,"2893"]
["KEGG Pathways","hsa00053","Ascorbate and aldarate metabolism",0.43079019269382607,0.8388229351479163,26.0,1.0,75322.46153846153,"219"]
["Reactome","R-HSA-1482839","Acyl chain remodelling of PE",0.43215621772439483,0.8634600281396245,28.0,1.0,133106.75,"8398"]
["Reactome","R-HSA-390918","Peroxisomal lipid metabolism",0.43420143329652966,0.8634600281396245,29.0,1.0,72824.93103448275,"8310"]
["Reactome","R-HSA-210745","Regulation of gene expression in beta cells",0.4345191309767266,0.8634600281396245,20.0,1.0,170773.75,"389692"]
["Reactome","R-HSA-2871809","FCERI mediated Ca+2 mobilization",0.4383615975035525,0.8639489473616185,32.0,2.0,141891.5625,"3708, 3937"]
["Reactome","R-HSA-606279","Deposition of new CENPA-containing nucleosomes at the centromere",0.4384785784388945,0.8639489473616185,68.0,2.0,59715.80882352941,"8607, 55839"]
["Reactome","R-HSA-774815","Nucleosome assembly",0.4384785784388945,0.8639489473616185,68.0,2.0,59715.80882352941,"8607, 55839"]
["Reactome","R-HSA-1268020","Mitochondrial protein import",0.44109140414104575,0.8639489473616185,60.0,2.0,50828.166666666664,"197257, 9804"]
["Reactome","R-HSA-72613","Eukaryotic Translation Initiation",0.4416898131805528,0.8639489473616185,119.0,5.0,59749.36974789916,"6122, 6123, 6159, 8664, 8892"]
["Reactome","R-HSA-72737","Cap-dependent Translation Initiation",0.4416898131805528,0.8639489473616185,119.0,5.0,59749.36974789916,"6122, 6123, 6159, 8664, 8892"]
["Reactome","R-HSA-450321","JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1",0.4419646326466004,0.8639489473616185,23.0,1.0,149441.52173913043,"5602"]
["Reactome","R-HSA-73864","RNA Polymerase I Transcription",0.44302564877084133,0.8644597948037536,107.0,3.0,40791.0,"1108, 2074, 9112"]
["Reactome","R-HSA-933541","TRAF6 mediated IRF7 activation",0.44561271269726227,0.865183385985311,35.0,1.0,57346.05714285714,"7186"]
["Reactome","R-HSA-5419276","Mitochondrial translation termination",0.44676984921810775,0.865183385985311,85.0,3.0,51909.31764705882,"51253, 51649, 64983"]
["Reactome","R-HSA-72689","Formation of a pool of free 40S subunits",0.4469568310666104,0.865183385985311,102.0,4.0,59044.470588235294,"6122, 6123, 6159, 8664"]
["Reactome","R-HSA-191859","snRNP Assembly",0.4481986088360538,0.865183385985311,52.0,2.0,69565.94230769231,"23225, 23279"]
["Reactome","R-HSA-194441","Metabolism of non-coding RNA",0.4481986088360538,0.865183385985311,52.0,2.0,69565.94230769231,"23225, 23279"]
["Reactome","R-HSA-8876198","RAB GEFs exchange GTP for GDP on RABs",0.4514851096006913,0.868425984836917,89.0,6.0,120287.73033707865,"83696, 6764, 10890, 22898, 23258, 54453"]
["Reactome","R-HSA-71291","Metabolism of amino acids and derivatives",0.45244651789023826,0.8687294597501733,352.0,23.0,101011.5625,"8659, 1491, 6122, 51582, 586, 1733, 4942, 4947, 4948, 4953, 5690, 6123, 6159, 6301, 7299, 8140, 8424, 8528, 54498, 57571, 64087, 256987, 374569"]
["KEGG Pathways","hsa00510","N-Glycan biosynthesis",0.45526402940211796,0.8491779749863747,49.0,3.0,261549.55102040817,"4248, 4249, 146664"]
["Reactome","R-HSA-5368286","Mitochondrial translation initiation",0.45530764072196916,0.8691902248354278,85.0,3.0,51450.69411764706,"51253, 51649, 64983"]
["Reactome","R-HSA-389661","Glyoxylate metabolism and glycine degradation",0.4561463769298392,0.8691902248354278,25.0,1.0,118971.48,"8528"]
["KEGG Pathways","hsa00860","Porphyrin and chlorophyll metabolism",0.4566757905928344,0.8491779749863747,43.0,2.0,79650.09302325582,"211, 2235"]
["Reactome","R-HSA-1482788","Acyl chain remodelling of PC",0.45695829813446237,0.8691902248354278,27.0,1.0,134105.85185185185,"8398"]
["Reactome","R-HSA-5621481","C-type lectin receptors (CLRs)",0.4575108584008866,0.8691902248354278,138.0,9.0,96240.13043478261,"3708, 4792, 997, 3553, 4790, 5058, 5690, 10892, 64581"]
["Reactome","R-HSA-6806003","Regulation of TP53 Expression and Degradation",0.4606296783083051,0.8720502316134463,36.0,2.0,118509.33333333333,"7874, 9099"]
["KEGG Pathways","hsa03013","RNA transport",0.46760284746514563,0.8491779749863747,149.0,9.0,92812.31543624161,"5976, 8664, 8892, 10250, 10940, 23225, 23279, 55520, 60528"]
["Reactome","R-HSA-446219","Synthesis of substrates in N-glycan biosythesis",0.4686022057188448,0.8833792309498087,63.0,4.0,130151.84126984127,"6482, 6487, 7903, 256435"]
["Reactome","R-HSA-73854","RNA Polymerase I Promoter Clearance",0.46928121240193466,0.8833792309498087,105.0,3.0,40796.52380952381,"1108, 2074, 9112"]
["Reactome","R-HSA-5389840","Mitochondrial translation elongation",0.4716628529411224,0.8833792309498087,86.0,3.0,49942.36046511628,"51253, 51649, 64983"]
["Reactome","R-HSA-179409","APC-Cdc20 mediated degradation of Nek2A",0.47233413088713183,0.8833792309498087,24.0,1.0,104637.20833333333,"4085"]
["Reactome","R-HSA-556833","Metabolism of lipids and lipoproteins",0.4732836190200821,0.8836262386195315,794.0,63.0,115715.77078085643,"9612, 51586, 55697, 56894, 114879, 32, 2581, 5046, 5295, 5500, 5660, 8871, 51422, 2, 196, 211, 857, 948, 1545, 2172, 2274, 2760, 3074, 3930, 3992, 4048, 4363, 4547, 4862, 5305, 5346, 5740, 6609, 7003, 7004, 7005, 8029, 8310, 8398, 8503, 8877, 9489, 9524, 9915, 10413, 10499, 10555, 11343, 22937, 23389, 23683, 23761, 26230, 27063, 27242, 29841, 51099, 57488, 57491, 65985, 81693, 114883, 253558"]
["KEGG Pathways","hsa05020","Prion diseases",0.4752137175116994,0.8491779749863747,35.0,2.0,144525.94285714286,"3553, 6352"]
["KEGG Pathways","hsa03040","Spliceosome",0.4768187762207955,0.8491779749863747,125.0,6.0,54806.616,"220988, 4809, 6430, 6627, 10772, 27258"]
["KEGG Pathways","hsa05010","Alzheimer's disease",0.47749852650755265,0.8491779749863747,158.0,10.0,102196.04430379746,"3708, 488, 489, 779, 2906, 3553, 6868, 23236, 23621, 84701"]
["Reactome","R-HSA-167172","Transcription of the HIV genome",0.48033223609692044,0.8897800061435712,74.0,3.0,60151.12162162162,"2957, 6873, 6881"]
["Reactome","R-HSA-69229","Ubiquitin-dependent degradation of Cyclin D1",0.48383623445633855,0.8897800061435712,51.0,2.0,64361.27450980392,"595, 5690"]
["Reactome","R-HSA-75815","Ubiquitin-dependent degradation of Cyclin D",0.48383623445633855,0.8897800061435712,51.0,2.0,64361.27450980392,"595, 5690"]
["Reactome","R-HSA-1169408","ISG15 antiviral mechanism",0.48416759944970483,0.8897800061435712,73.0,4.0,83569.83561643836,"6772, 23225, 23279, 317649"]
["Reactome","R-HSA-1169410","Antiviral mechanism by IFN-stimulated genes",0.48416759944970483,0.8897800061435712,73.0,4.0,83569.83561643836,"6772, 23225, 23279, 317649"]
["Reactome","R-HSA-975298","Ligand-gated ion channel transport",0.4848107526536202,0.8897800061435712,26.0,2.0,203521.88461538462,"2569, 2570"]
["Reactome","R-HSA-211859","Biological oxidations",0.49003918624613285,0.8960054205138521,216.0,14.0,90410.70370370371,"5447, 196, 219, 1545, 2948, 2950, 5740, 8639, 9915, 10499, 54498, 57491, 64757, 84532"]
["KEGG Pathways","hsa00590","Arachidonic acid metabolism",0.49244002034214035,0.8491779749863747,58.0,3.0,95414.13793103448,"4048, 5740, 8398"]
["KEGG Pathways","hsa04630","Jak-STAT signaling pathway",0.49304372052607,0.8491779749863747,155.0,12.0,235974.05806451614,"595, 598, 5295, 5618, 6776, 1437, 3596, 6655, 6772, 6777, 8503, 11009"]
["Reactome","R-HSA-1296072","Voltage gated Potassium channels",0.4933024656806109,0.8960054205138521,44.0,4.0,265565.70454545453,"3741, 7881, 9132, 26251"]
["Reactome","R-HSA-3858494","Beta-catenin independent WNT signaling",0.4936732635745635,0.8960054205138521,144.0,10.0,118511.45138888889,"3708, 815, 1499, 5690, 5879, 7474, 8324, 23112, 23236, 59345"]
["Reactome","R-HSA-1963640","GRB2 events in ERBB2 signaling",0.4993804734957982,0.9012191850566909,16.0,1.0,338906.25,"1956"]
["KEGG Pathways","hsa03430","Mismatch repair",0.5006280432686366,0.8491779749863747,23.0,1.0,150646.73913043478,"27030"]
["Reactome","R-HSA-5689901","Metalloprotease DUBs",0.5039934894343733,0.9070911830265367,35.0,1.0,48892.42857142857,"114803"]
["Reactome","R-HSA-1296071","Potassium Channels",0.5045425059617274,0.9070911830265367,100.0,9.0,244140.19,"3741, 3773, 3777, 3779, 3782, 7881, 9132, 26251, 51305"]
["Reactome","R-HSA-1538133","G0 and Early G1",0.5071802784731025,0.9070911830265367,25.0,1.0,78836.96,"1859"]
["KEGG Pathways","hsa00983","Drug metabolism - other enzymes",0.5079441291175217,0.8535126759761635,51.0,3.0,90118.43137254902,"7378, 51733, 54963"]
["Reactome","R-HSA-71387","Metabolism of carbohydrates",0.5103120285124818,0.9087931349743148,291.0,23.0,157972.22680412373,"3098, 960, 2632, 3074, 3101, 3340, 5091, 5208, 5209, 5210, 5214, 5224, 5257, 6383, 6482, 6487, 6518, 6526, 22856, 23225, 23279, 166012, 337876"]
["Reactome","R-HSA-452723","Transcriptional regulation of pluripotent stem cells",0.51127285071801,0.9087931349743148,36.0,2.0,191494.97222222222,"2034, 27086"]
["Reactome","R-HSA-174417","Telomere C-strand (Lagging Strand) Synthesis",0.512379409643948,0.9087931349743148,24.0,1.0,99480.04166666667,"56655"]
["Reactome","R-HSA-1660514","Synthesis of PIPs at the Golgi membrane",0.5140186177441328,0.9094175544703889,19.0,1.0,131574.26315789475,"55697"]
["Reactome","R-HSA-428930","Thromboxane signalling through TP receptor",0.5152308582197905,0.9100728067575058,23.0,1.0,89237.91304347826,"59345"]
["KEGG Pathways","hsa05216","Thyroid cancer",0.516354321116496,0.8605905351941601,29.0,2.0,130776.13793103448,"595, 1499"]
["Reactome","R-HSA-1482801","Acyl chain remodelling of PS",0.5194246059649079,0.9133278987106366,22.0,1.0,167399.4090909091,"114879"]
["Reactome","R-HSA-5250913","Positive epigenetic regulation of rRNA expression",0.5197015897821518,0.9133278987106366,103.0,3.0,34119.25242718447,"1108, 2074, 9112"]
["KEGG Pathways","hsa00512","Mucin type O-Glycan biosynthesis",0.5205565692750103,0.8605975540433638,30.0,3.0,284159.1,"2590, 6482, 117248"]
["Reactome","R-HSA-6804757","Regulation of TP53 Degradation",0.52130844466896,0.9133278987106366,35.0,2.0,108671.28571428571,"7874, 9099"]
["Reactome","R-HSA-6785631","ERBB2 Regulates Cell Motility",0.5214464797937044,0.9133278987106366,15.0,1.0,358506.4666666667,"1956"]
["Reactome","R-HSA-5223345","Miscellaneous transport and binding events",0.5231630454950773,0.9133278987106366,21.0,1.0,107096.47619047618,"2039"]
["Reactome","R-HSA-72203","Processing of Capped Intron-Containing Pre-mRNA",0.5256665422008131,0.9138040162822483,242.0,13.0,71611.80578512397,"220988, 3187, 4809, 6430, 6627, 10212, 10250, 10772, 11066, 23225, 23279, 27258, 84248"]
["Reactome","R-HSA-6802952","Signaling by BRAF and RAF fusions",0.5257965755111549,0.9138040162822483,62.0,5.0,147018.5,"23164, 22906, 4000, 9444, 23499"]
["Reactome","R-HSA-162587","HIV Life Cycle",0.5288525983635122,0.914737433754008,148.0,8.0,76285.83108108108,"1104, 2957, 4836, 6873, 6881, 23225, 23279, 23327"]
["Reactome","R-HSA-975577","N-Glycan antennae elongation",0.5354854460947791,0.9203022808952115,15.0,1.0,202395.13333333333,"4249"]
["Reactome","R-HSA-5601884","PIWI-interacting RNA (piRNA) biogenesis",0.5370892862644097,0.9203022808952115,29.0,1.0,55879.379310344826,"143689"]
["Reactome","R-HSA-380320","Recruitment of NuMA to mitotic centrosomes",0.5379481775019774,0.9203022808952115,28.0,1.0,65905.32142857143,"10844"]
["KEGG Pathways","hsa00980","Metabolism of xenobiotics by cytochrome P450",0.5380846511686126,0.8617761991372311,70.0,4.0,68243.41428571429,"220, 1545, 2948, 2950"]
["Reactome","R-HSA-4615885","SUMOylation of DNA replication proteins",0.539996795046447,0.9203022808952115,44.0,2.0,76021.93181818182,"23225, 23279"]
["Reactome","R-HSA-209776","Amine-derived hormones",0.5415882875732732,0.9203022808952115,18.0,1.0,174755.77777777778,"1733"]
["Reactome","R-HSA-927802","Nonsense-Mediated Decay (NMD)",0.543264554783951,0.9203022808952115,115.0,5.0,57593.11304347826,"6122, 5520, 5976, 6123, 6159"]
["Reactome","R-HSA-975957","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)",0.543264554783951,0.9203022808952115,115.0,5.0,57593.11304347826,"6122, 5520, 5976, 6123, 6159"]
["Reactome","R-HSA-196299","Beta-catenin phosphorylation cascade",0.5485115254172136,0.9264702484000122,17.0,1.0,133881.0,"1499"]
["Reactome","R-HSA-392170","ADP signalling through P2Y purinoceptor 12",0.5499085924017968,0.9273809491206589,23.0,1.0,78148.34782608696,"59345"]
["Reactome","R-HSA-197264","Nicotinamide salvaging",0.5547343277487911,0.934062006692279,18.0,1.0,156006.38888888888,"5740"]
["Reactome","R-HSA-5696400","Dual Incision in GG-NER",0.5632122062271956,0.9463270490443179,41.0,2.0,80732.9512195122,"51426, 56655"]
["Reactome","R-HSA-425407","SLC-mediated transmembrane transport",0.5637693058136362,0.9463270490443179,282.0,23.0,135649.31560283687,"55117, 861, 3098, 6546, 3101, 6518, 6526, 6533, 6536, 6560, 6575, 8140, 9123, 10723, 23225, 23279, 23315, 30061, 55089, 56606, 57030, 83733, 340024"]
["KEGG Pathways","hsa00280","Valine, leucine and isoleucine degradation",0.5640530313225691,0.8774105661570508,44.0,3.0,120547.04545454546,"219, 586, 64087"]
["Reactome","R-HSA-937041","IKK complex recruitment mediated by RIP1",0.5658368096716829,0.9471294400750497,24.0,1.0,95898.625,"8737"]
["Reactome","R-HSA-5653656","Vesicle-mediated transport",0.5659996468903628,0.9471294400750497,662.0,54.0,119051.05589123868,"1282, 1284, 23216, 56894, 6272, 8871, 51422, 51429, 83696, 154, 286, 288, 948, 966, 1062, 1277, 1523, 1956, 2590, 2701, 2844, 3267, 3797, 4481, 4621, 5879, 6764, 7082, 7164, 7474, 8301, 8398, 8675, 9026, 9146, 9698, 10052, 10540, 10618, 10890, 10920, 10971, 11267, 22898, 23166, 23258, 23299, 26258, 51332, 54453, 57731, 84694, 90019, 219770"]
["KEGG Pathways","hsa04614","Renin-angiotensin system",0.5671935902168083,0.8774105661570508,17.0,1.0,163073.17647058822,"1636"]
["Reactome","R-HSA-162588","Budding and maturation of HIV virion",0.5672788928923548,0.9478029106903176,25.0,1.0,100531.84,"23327"]
["KEGG Pathways","hsa05217","Basal cell carcinoma",0.5684210707877462,0.8774105661570508,55.0,5.0,187471.14545454545,"1499, 2736, 7474, 7477, 8324"]
["Reactome","R-HSA-73847","Purine metabolism",0.5685136156947794,0.9484000286513219,34.0,2.0,103992.20588235294,"2766, 122622"]
["Reactome","R-HSA-5334118","DNA methylation",0.5737763127633962,0.9526548925257708,60.0,1.0,18377.566666666666,"1788"]
["Reactome","R-HSA-5658442","Regulation of RAS by GAPs",0.5750888638707337,0.9526548925257708,69.0,4.0,91110.95652173914,"153090, 22821, 5690, 5921"]
["KEGG Pathways","hsa03018","RNA degradation",0.5765482788591328,0.8774105661570508,71.0,5.0,129624.01408450704,"4850, 10140, 27258, 196513, 255967"]
["Reactome","R-HSA-110373","Resolution of AP sites via the multiple-nucleotide patch replacement pathway",0.5798084262306609,0.9526548925257708,24.0,1.0,76488.20833333333,"56655"]
["Reactome","R-HSA-4839743","phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-5339716","Misspliced GSK3beta mutants stabilize beta-catenin",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-5358747","S33 mutants of beta-catenin aren't phosphorylated",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-5358749","S37 mutants of beta-catenin aren't phosphorylated",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-5358751","S45 mutants of beta-catenin aren't phosphorylated",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-5358752","T41 mutants of beta-catenin aren't phosphorylated",0.5798768911026432,0.9526548925257708,15.0,1.0,148727.33333333334,"1499"]
["Reactome","R-HSA-8864260","Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors",0.5822983432218409,0.9534029661523924,39.0,3.0,175306.2564102564,"1956, 2099, 79047"]
["Reactome","R-HSA-110313","Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template",0.586801346595835,0.9534029661523924,41.0,2.0,77717.46341463414,"51426, 56655"]
["Reactome","R-HSA-4641262","Disassembly of the destruction complex and recruitment of AXIN to the membrane",0.5880908709147428,0.9534029661523924,31.0,2.0,118650.03225806452,"857, 1499"]
["Reactome","R-HSA-499943","Synthesis and interconversion of nucleotide di- and triphosphates",0.5899287600509231,0.9534029661523924,24.0,1.0,67245.33333333333,"204"]
["Reactome","R-HSA-5686938","Regulation of TLR by endogenous ligand",0.5921470097549872,0.9534029661523924,19.0,1.0,192590.94736842104,"948"]
["Reactome","R-HSA-8863795","Downregulation of ERBB2 signaling",0.592168940542192,0.9534029661523924,30.0,2.0,215450.3,"1956, 5782"]
["Reactome","R-HSA-3232118","SUMOylation of transcription factors",0.5933034322682238,0.9534029661523924,17.0,1.0,175559.41176470587,"9112"]
["KEGG Pathways","hsa05330","Allograft rejection",0.5935087402267318,0.8774105661570508,35.0,2.0,80025.22857142857,"356, 958"]
["Reactome","R-HSA-168253","Host Interactions with Influenza Factors",0.5979391168140219,0.9534029661523924,41.0,2.0,76442.87804878049,"23225, 23279"]
["Reactome","R-HSA-141405","Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components",0.5993332278733878,0.9534029661523924,19.0,1.0,116412.84210526316,"4085"]
["Reactome","R-HSA-141430","Inactivation of APC/C via direct inhibition of the APC/C complex",0.5993332278733878,0.9534029661523924,19.0,1.0,116412.84210526316,"4085"]
["Reactome","R-HSA-5617472","Activation of anterior HOX genes in hindbrain development during early embryogenesis",0.6003706058985552,0.9534029661523924,118.0,5.0,70945.28813559322,"3199, 3213, 84962, 5914, 9935"]
["Reactome","R-HSA-5619507","Activation of HOX genes during differentiation",0.6003706058985552,0.9534029661523924,118.0,5.0,70945.28813559322,"3199, 3213, 84962, 5914, 9935"]
["Reactome","R-HSA-5205647","Mitophagy",0.6035315442450822,0.9534029661523924,22.0,1.0,108965.27272727272,"9804"]
["Reactome","R-HSA-5205685","Pink/Parkin Mediated Mitophagy",0.6035315442450822,0.9534029661523924,22.0,1.0,108965.27272727272,"9804"]
["Reactome","R-HSA-109606","Intrinsic Pathway for Apoptosis",0.6036422748779662,0.9534029661523924,44.0,3.0,106356.36363636363,"598, 4836, 10971"]
["Reactome","R-HSA-74158","RNA Polymerase III Transcription",0.6041624667687876,0.9534029661523924,41.0,2.0,90088.87804878049,"4781, 171568"]
["Reactome","R-HSA-749476","RNA Polymerase III Abortive And Retractive Initiation",0.6041624667687876,0.9534029661523924,41.0,2.0,90088.87804878049,"4781, 171568"]
["Reactome","R-HSA-202424","Downstream TCR signaling",0.6050272292141917,0.9534029661523924,95.0,6.0,100863.1052631579,"4792, 5295, 997, 4790, 5690, 10892"]
["Reactome","R-HSA-1227986","Signaling by ERBB2",0.6094940168767378,0.9537751246993038,51.0,4.0,195515.96078431373,"5295, 1956, 2549, 5782"]
["Reactome","R-HSA-5693571","Nonhomologous End-Joining (NHEJ)",0.6097841511305329,0.9537751246993038,67.0,3.0,61405.253731343284,"7336, 7468, 79840"]
["KEGG Pathways","hsa00531","Glycosaminoglycan degradation",0.6114481595310279,0.8789952944074227,18.0,1.0,123291.72222222222,"3074"]
["Reactome","R-HSA-202131","Metabolism of nitric oxide",0.612031275024123,0.9537751246993038,21.0,1.0,80141.09523809524,"857"]
["Reactome","R-HSA-203765","eNOS activation and regulation",0.612031275024123,0.9537751246993038,21.0,1.0,80141.09523809524,"857"]
["Reactome","R-HSA-166208","mTORC1-mediated signalling",0.6123530917025689,0.9537751246993038,22.0,1.0,89904.54545454546,"57521"]
["Reactome","R-HSA-5696399","Global Genome Nucleotide Excision Repair (GG-NER)",0.6146839165041107,0.9537751246993038,84.0,5.0,84202.69047619047,"7336, 8607, 10920, 51426, 56655"]
["Reactome","R-HSA-1221632","Meiotic synapsis",0.6149687899310035,0.9537751246993038,75.0,3.0,68635.96,"23353, 23345, 4000"]
["Reactome","R-HSA-76071","RNA Polymerase III Transcription Initiation From Type 3 Promoter",0.6173541514850218,0.955636356021465,28.0,1.0,54246.92857142857,"171568"]
["Reactome","R-HSA-975956","Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)",0.617936922163741,0.955636356021465,95.0,4.0,55515.97894736842,"6122, 5976, 6123, 6159"]
["KEGG Pathways","hsa05332","Graft-versus-host disease",0.6234564392382311,0.8789952944074227,37.0,2.0,68624.62162162163,"356, 3553"]
["KEGG Pathways","hsa00450","Selenocompound metabolism",0.6236712683918912,0.8789952944074227,17.0,1.0,99407.17647058824,"1491"]
["Reactome","R-HSA-975576","N-glycan antennae elongation in the medial/trans-Golgi",0.6255448240598136,0.9614403062839793,26.0,2.0,178437.73076923078,"4248, 4249"]
["Reactome","R-HSA-2871837","FCERI mediated NF-kB activation",0.6276443633313769,0.9614403062839793,81.0,5.0,87224.03703703704,"4792, 997, 4790, 5690, 10892"]
["Reactome","R-HSA-500792","GPCR ligand binding",0.6280280216246603,0.9614403062839793,446.0,38.0,137382.81614349777,"1889, 623, 1909, 1910, 2852, 5660, 152, 153, 154, 624, 718, 728, 885, 886, 976, 1236, 1325, 1814, 1902, 2867, 3274, 3357, 3363, 5368, 5734, 5739, 6352, 6363, 6387, 6865, 7474, 7477, 8324, 8620, 59345, 90226, 122876, 339403"]
["Reactome","R-HSA-159234","Transport of Mature mRNAs Derived from Intronless Transcripts",0.6308910817743232,0.9614809942443727,42.0,2.0,72932.04761904762,"23225, 23279"]
["Reactome","R-HSA-168276"," NS1 Mediated Effects on Host Pathways",0.6315998033340808,0.9614809942443727,39.0,2.0,78556.89743589744,"23225, 23279"]
["KEGG Pathways","hsa00330","Arginine and proline metabolism",0.6321709340553018,0.8803820723878223,54.0,4.0,122863.70370370371,"8659, 219, 4942, 4953"]
["Reactome","R-HSA-432142","Platelet sensitization by LDL",0.6328781463435049,0.9614809942443727,16.0,1.0,275478.875,"7804"]
["Reactome","R-HSA-5654732","Negative regulation of FGFR3 signaling",0.6352121368601076,0.9615701311708494,29.0,2.0,182668.6551724138,"2246, 2254"]
["Reactome","R-HSA-191273","Cholesterol biosynthesis",0.6377851841345967,0.9615701311708494,24.0,1.0,58723.75,"3930"]
["KEGG Pathways","hsa05219","Bladder cancer",0.6429498647585674,0.8803820723878223,42.0,3.0,104225.90476190476,"595, 1956, 7057"]
["Reactome","R-HSA-1660499","Synthesis of PIPs at the plasma membrane",0.6430751314406995,0.9645317125876526,49.0,4.0,151780.14285714287,"5295, 8871, 5305, 8503"]
["Reactome","R-HSA-159231","Transport of Mature mRNA Derived from an Intronless Transcript",0.6433185613096184,0.9645317125876526,41.0,2.0,74291.31707317074,"23225, 23279"]
["KEGG Pathways","hsa04720","Long-term potentiation",0.6441820041862114,0.8803820723878223,69.0,7.0,221479.27536231885,"818, 3708, 5500, 6196, 815, 2906, 23236"]
["Reactome","R-HSA-5633007","Regulation of TP53 Activity",0.6464256457090882,0.9660160307860525,162.0,12.0,101500.74074074074,"28996, 51422, 1108, 3622, 5305, 5608, 6794, 6873, 6881, 7874, 9099, 9891"]
["Reactome","R-HSA-5610787","Hedgehog 'off' state",0.6469894600269214,0.9660160307860525,113.0,8.0,109198.30973451327,"5575, 109, 115, 108, 111, 2736, 5690, 27152"]
["Reactome","R-HSA-674695","RNA Polymerase II Pre-transcription Events",0.6508933352551547,0.9679153478380259,85.0,4.0,54134.7294117647,"2957, 6873, 6881, 85403"]
["Reactome","R-HSA-6804756","Regulation of TP53 Activity through Phosphorylation",0.6509476946144725,0.9679153478380259,93.0,6.0,87669.89247311828,"28996, 51422, 6794, 6873, 6881, 9891"]
["KEGG Pathways","hsa03030","DNA replication",0.6573769462431447,0.8865939077621359,36.0,2.0,123431.02777777778,"56655, 79621"]
["Reactome","R-HSA-1169091","Activation of NF-kappaB in B cells",0.658885538223307,0.9679424859847289,67.0,4.0,86314.25373134328,"4792, 4790, 5690, 10892"]
["Reactome","R-HSA-76061","RNA Polymerase III Transcription Initiation From Type 1 Promoter",0.6630761615119887,0.9679424859847289,28.0,1.0,45768.67857142857,"171568"]
["Reactome","R-HSA-354194","GRB2:SOS provides linkage to MAPK signaling for Integrins ",0.6644053647120953,0.9679424859847289,15.0,1.0,124619.26666666666,"5747"]
["Reactome","R-HSA-69202","Cyclin E associated events during G1/S transition ",0.6684613894709346,0.9679424859847289,71.0,4.0,75466.66197183098,"595, 1027, 5690, 7465"]
["Reactome","R-HSA-622312","Inflammasomes",0.668944824344639,0.9679424859847289,17.0,1.0,114265.88235294117,"598"]
["Reactome","R-HSA-68875","Mitotic Prophase",0.6713721479155071,0.9679424859847289,135.0,7.0,79970.88148148148,"4000, 7444, 10783, 23225, 23279, 23310, 79648"]
["Reactome","R-HSA-211000","Gene Silencing by RNA",0.673475396663151,0.9679424859847289,131.0,6.0,62088.87786259542,"7247, 23112, 23225, 23279, 23405, 143689"]
["Reactome","R-HSA-3371453","Regulation of HSF1-mediated heat shock response",0.6774156625877932,0.9679424859847289,68.0,4.0,77339.51470588235,"3308, 10049, 23225, 23279"]
["Reactome","R-HSA-977225","Amyloid fiber formation",0.6794540648581142,0.9679424859847289,95.0,4.0,61505.642105263156,"6477, 2934, 4878, 23621"]
["Reactome","R-HSA-174824","Lipoprotein metabolism",0.6822295128918408,0.9679424859847289,71.0,5.0,125952.22535211267,"5046, 2, 4547, 8029, 81693"]
["Reactome","R-HSA-351202","Metabolism of polyamines",0.6912444323391994,0.9679424859847289,86.0,5.0,69207.82558139534,"51582, 4947, 4953, 5690, 54498"]
["Reactome","R-HSA-2299718","Condensation of Prophase Chromosomes",0.693323360408675,0.9679424859847289,69.0,2.0,45428.014492753624,"23310, 79648"]
["Reactome","R-HSA-6788656","Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism",0.6935324048451069,0.9679424859847289,44.0,3.0,117810.27272727272,"8659, 8140, 57571"]
["Reactome","R-HSA-8875360","InlB-mediated entry of Listeria monocytogenes into host cell",0.6939278659047545,0.9679424859847289,15.0,1.0,142410.8,"9146"]
["Reactome","R-HSA-354192","Integrin alphaIIb beta3 signaling",0.6962457955824559,0.9679424859847289,27.0,2.0,120760.11111111111,"5747, 9564"]
["Reactome","R-HSA-3322077","Glycogen synthesis",0.6974424640824659,0.9679424859847289,15.0,1.0,292645.4,"2632"]
["Reactome","R-HSA-399719","Trafficking of AMPA receptors",0.6983049592637165,0.9679424859847289,31.0,3.0,235899.29032258064,"818, 815, 2893"]
["Reactome","R-HSA-399721","Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity",0.6983049592637165,0.9679424859847289,31.0,3.0,235899.29032258064,"818, 815, 2893"]
["KEGG Pathways","hsa04130","SNARE interactions in vesicular transport",0.7001229895616227,0.9183863935985515,34.0,2.0,73767.44117647059,"8675, 9482"]
["Reactome","R-HSA-5655862","Translesion synthesis by POLK",0.7022626932190756,0.9679424859847289,17.0,1.0,109040.0,"51426"]
["Reactome","R-HSA-70221","Glycogen breakdown (glycogenolysis)",0.703307240318108,0.9679424859847289,16.0,1.0,103642.25,"5257"]
["Reactome","R-HSA-2408557","Selenocysteine synthesis",0.7036463015768228,0.9679424859847289,92.0,4.0,54177.77173913043,"6122, 6123, 6159, 6301"]
["Reactome","R-HSA-73857","RNA Polymerase II Transcription",0.7055842497669736,0.9679424859847289,153.0,8.0,57899.294117647056,"2957, 6430, 6873, 6881, 10212, 10250, 84248, 85403"]
["Reactome","R-HSA-3928665","EPH-ephrin mediated repulsion of cells",0.7060679984277385,0.9679424859847289,49.0,4.0,293750.8367346939,"1969, 2043, 2047, 5879"]
["Reactome","R-HSA-187577","SCF(Skp2)-mediated degradation of p27/p21",0.7097021583529393,0.9679424859847289,60.0,3.0,61602.46666666667,"595, 1027, 5690"]
["Reactome","R-HSA-76066","RNA Polymerase III Transcription Initiation From Type 2 Promoter",0.7099234957898763,0.9679424859847289,27.0,1.0,44274.74074074074,"171568"]
["Reactome","R-HSA-983695","Antigen activates B Cell Receptor (BCR) leading to generation of second messengers",0.7105261051173561,0.9679424859847289,37.0,3.0,164387.8918918919,"3708, 5295, 100616453"]
["Reactome","R-HSA-420029","Tight junction interactions",0.7128452741760998,0.9679424859847289,30.0,2.0,114485.63333333333,"49861, 56288"]
["Reactome","R-HSA-176033","Interactions of Vpr with host cellular proteins",0.7130082078446908,0.9679424859847289,35.0,2.0,82988.4857142857,"23225, 23279"]
["Reactome","R-HSA-5696394","DNA Damage Recognition in GG-NER",0.7151258486128382,0.9679424859847289,38.0,2.0,68232.94736842105,"8607, 10920"]
["Reactome","R-HSA-5365859","RA biosynthesis pathway",0.7200832097606183,0.9679424859847289,23.0,2.0,156515.4347826087,"220, 157506"]
["Reactome","R-HSA-1250196","SHC1 events in ERBB2 signaling",0.7212995816619755,0.9679424859847289,22.0,2.0,288299.1818181818,"1956, 5782"]
["Reactome","R-HSA-416700","Other semaphorin interactions",0.7230808219533909,0.9679424859847289,19.0,2.0,349315.36842105264,"23129, 3688"]
["Reactome","R-HSA-5651801","PCNA-Dependent Long Patch Base Excision Repair",0.7233970476514406,0.9679424859847289,21.0,1.0,72240.09523809524,"56655"]
["Reactome","R-HSA-168325","Viral Messenger RNA Synthesis",0.7289337134650212,0.9679424859847289,42.0,2.0,65997.71428571429,"23225, 23279"]
["Reactome","R-HSA-388841","Costimulation by the CD28 family",0.7311550861967359,0.9679424859847289,67.0,5.0,105345.89552238806,"5295, 1493, 5058, 5879, 8503"]
["Reactome","R-HSA-164952","The role of Nef in HIV-1 replication and disease pathogenesis",0.7321580362860071,0.9679424859847289,29.0,2.0,109781.86206896552,"1794, 5879"]
["KEGG Pathways","hsa04080","Neuroactive ligand-receptor interaction",0.7326625913114809,0.9285469066549737,269.0,29.0,221734.72118959107,"623, 1909, 1910, 2908, 5618, 7434, 151, 152, 153, 154, 624, 728, 886, 1814, 1902, 2569, 2570, 2893, 2906, 3274, 3357, 3363, 5023, 5734, 5739, 6865, 7067, 7442, 56288"]
["KEGG Pathways","hsa00340","Histidine metabolism",0.733778531112711,0.9285469066549737,29.0,2.0,108354.4827586207,"220, 219"]
["Reactome","R-HSA-912694","Regulation of IFNA signaling",0.7351285832398928,0.9679424859847289,26.0,1.0,43956.57692307692,"6772"]
["Reactome","R-HSA-5675221","Negative regulation of MAPK pathway",0.7413211091719314,0.9679424859847289,40.0,3.0,107867.1,"1843, 1847, 5536"]
["Reactome","R-HSA-4419969","Depolymerisation of the Nuclear Lamina",0.7422139205389204,0.9679424859847289,15.0,1.0,103237.73333333334,"4000"]
["Reactome","R-HSA-111447","Activation of BAD and translocation to mitochondria ",0.7423441614633836,0.9679424859847289,15.0,1.0,108982.8,"10971"]
["Reactome","R-HSA-389977","Post-chaperonin tubulin folding pathway",0.7450909200570618,0.9679424859847289,22.0,1.0,58898.5,"6904"]
["Reactome","R-HSA-456926","Thrombin signalling through proteinase activated receptors (PARs)",0.7460004590270763,0.9679424859847289,32.0,2.0,82652.25,"2768, 59345"]
["Reactome","R-HSA-913531","Interferon Signaling",0.7472251171671073,0.9679424859847289,194.0,13.0,87270.73195876289,"818, 684, 815, 960, 3394, 3662, 6672, 6772, 23225, 23279, 23321, 163351, 317649"]
["KEGG Pathways","hsa00350","Tyrosine metabolism",0.747624179881107,0.9320732889049409,41.0,3.0,127949.0,"220, 7299, 8639"]
["Reactome","R-HSA-69656","Cyclin A:Cdk2-associated events at S phase entry",0.74781121375241,0.9679424859847289,70.0,4.0,70659.61428571428,"595, 1027, 5690, 7465"]
["Reactome","R-HSA-176407","Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase",0.7497402586897659,0.9679424859847289,18.0,1.0,77962.77777777778,"8556"]
["KEGG Pathways","hsa00511","Other glycan degradation",0.7502893436636044,0.9320732889049409,16.0,1.0,93165.875,"3074"]
["Reactome","R-HSA-202427","Phosphorylation of CD3 and TCR zeta chains",0.7509060461295916,0.9679424859847289,20.0,1.0,65165.05,"5795"]
["Reactome","R-HSA-913709","O-linked glycosylation of mucins",0.7515611598100049,0.9679424859847289,61.0,6.0,189459.80327868852,"2590, 6482, 6487, 117248, 146712, 256435"]
["Reactome","R-HSA-112314","Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell",0.7528115230290993,0.9679424859847289,144.0,15.0,208177.77083333334,"109, 115, 818, 6196, 108, 111, 815, 2569, 2570, 2893, 2906, 3773, 23236, 59345, 83988"]
["Reactome","R-HSA-198725","Nuclear Events (kinase and transcription factor activation)",0.753383582925204,0.9679424859847289,25.0,2.0,159415.84,"6196, 4208"]
["KEGG Pathways","hsa03020","RNA polymerase",0.7591570201929811,0.9320732889049409,29.0,1.0,33872.862068965514,"171568"]
["Reactome","R-HSA-166663","Initial triggering of complement",0.7637347022990504,0.9679424859847289,22.0,1.0,94396.09090909091,"718"]
["Reactome","R-HSA-6807878","COPI-mediated anterograde transport",0.7651055201134733,0.9679424859847289,94.0,6.0,80055.40425531915,"286, 288, 966, 10540, 51332, 57731"]
["Reactome","R-HSA-201722","Formation of the beta-catenin:TCF transactivating complex",0.7670229711493036,0.9679424859847289,86.0,4.0,88147.0,"1499, 7090, 8607, 283149"]
["Reactome","R-HSA-72165","mRNA Splicing - Minor Pathway",0.7695718933368961,0.9679424859847289,53.0,2.0,37166.49056603773,"4809, 11066"]
["KEGG Pathways","hsa00030","Pentose phosphate pathway",0.77438805394656,0.9320732889049409,27.0,2.0,99175.25925925926,"5214, 9563"]
["KEGG Pathways","hsa04340","Hedgehog signaling pathway",0.7763440040490325,0.9320732889049409,56.0,6.0,198174.8392857143,"653, 654, 2736, 7474, 7477, 53944"]
["Reactome","R-HSA-8849932","SALM protein interactions at the synapses",0.7765398253433833,0.9679424859847289,21.0,2.0,415532.28571428574,"2893, 2906"]
["Reactome","R-HSA-2022854","Keratan sulfate biosynthesis",0.7794576090406249,0.9679424859847289,27.0,2.0,116729.92592592593,"6482, 6487"]
["Reactome","R-HSA-2142753","Arachidonic acid metabolism",0.7805527018569995,0.9679424859847289,58.0,4.0,106031.58620689655,"1545, 4048, 4363, 5740"]
["KEGG Pathways","hsa05320","Autoimmune thyroid disease",0.782089465721758,0.9321415143776766,50.0,3.0,64468.06,"356, 958, 1493"]
["Reactome","R-HSA-162599","Late Phase of HIV Life Cycle",0.782627976456057,0.9679424859847289,135.0,8.0,73947.04444444444,"1104, 2957, 4836, 6873, 6881, 23225, 23279, 23327"]
["Reactome","R-HSA-1793185","Chondroitin sulfate/dermatan sulfate metabolism",0.7862010080164131,0.9679424859847289,50.0,5.0,234508.3,"3074, 6383, 22856, 166012, 337876"]
["Reactome","R-HSA-8856828","Clathrin-mediated endocytosis",0.7876871502890007,0.9679424859847289,138.0,12.0,129952.10869565218,"8871, 51429, 154, 1956, 3267, 7474, 8301, 9026, 9146, 10618, 10920, 90019"]
["Reactome","R-HSA-1234176","Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha",0.7900079906527314,0.9679424859847289,66.0,4.0,77815.0303030303,"2034, 3091, 84962, 5690"]
["Reactome","R-HSA-6803529","FGFR2 alternative splicing",0.7929679747965772,0.9679424859847289,27.0,1.0,43019.444444444445,"3187"]
["Reactome","R-HSA-549132","Organic cation/anion/zwitterion transport",0.7932712950250673,0.9679424859847289,15.0,1.0,113669.33333333333,"861"]
["KEGG Pathways","hsa04650","Natural killer cell mediated cytotoxicity",0.795198478161214,0.9362369766293241,130.0,10.0,92272.13846153846,"5295, 356, 1437, 3937, 5058, 5879, 6452, 6655, 8503, 8795"]
["KEGG Pathways","hsa00534","Glycosaminoglycan biosynthesis - heparan sulfate / heparin",0.80007343397314,0.9362369766293241,26.0,3.0,357643.1923076923,"2137, 2134, 3340"]
["KEGG Pathways","hsa00601","Glycosphingolipid biosynthesis - lacto and neolacto series",0.8037936970085905,0.9362369766293241,26.0,2.0,172696.11538461538,"2651, 6487"]
["Reactome","R-HSA-203927","MicroRNA (miRNA) biogenesis",0.8048055125655695,0.9679424859847289,25.0,1.0,47518.08,"23405"]
["Reactome","R-HSA-156590","Glutathione conjugation",0.8112306747763595,0.9679424859847289,36.0,2.0,59965.555555555555,"2948, 2950"]
["Reactome","R-HSA-168643","Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",0.8134540173284899,0.9679424859847289,52.0,4.0,119780.25,"598, 1540, 5608, 7128"]
["Reactome","R-HSA-381119","Unfolded Protein Response (UPR)",0.8179187272282635,0.9679424859847289,88.0,5.0,57193.40909090909,"2137, 4000, 7709, 9114, 116138"]
["Reactome","R-HSA-6790901","rRNA modification in the nucleus and cytosol",0.8204538588554577,0.9679424859847289,60.0,3.0,54203.38333333333,"4809, 25879, 55226"]
["Reactome","R-HSA-5696398","Nucleotide Excision Repair",0.8279613525574843,0.9679424859847289,111.0,7.0,73954.97297297297,"2074, 7336, 7874, 8607, 10920, 51426, 56655"]
["KEGG Pathways","hsa03320","PPAR signaling pathway",0.8292659757169136,0.9550535113593669,70.0,5.0,75551.52857142857,"948, 2172, 5346, 8310, 126129"]
["Reactome","R-HSA-5362517","Signaling by Retinoic Acid",0.8293921754190177,0.9679424859847289,43.0,4.0,140887.88372093023,"220, 5164, 5914, 157506"]
["Reactome","R-HSA-2162123","Synthesis of Prostaglandins (PG) and Thromboxanes (TX)",0.8296583124234904,0.9679424859847289,15.0,1.0,82669.53333333334,"5740"]
["Reactome","R-HSA-180910","Vpr-mediated nuclear import of PICs",0.8325656218831596,0.9679424859847289,32.0,2.0,83283.78125,"23225, 23279"]
["Reactome","R-HSA-112409","RAF-independent MAPK1/3 activation",0.8328386056129332,0.9679424859847289,23.0,2.0,131988.08695652173,"1843, 1847"]
["Reactome","R-HSA-159230","Transport of the SLBP Dependant Mature mRNA",0.8331878117466176,0.9679424859847289,33.0,2.0,81106.93939393939,"23225, 23279"]
["Reactome","R-HSA-5099900","WNT5A-dependent internalization of FZD4",0.8354109375407794,0.9679424859847289,15.0,1.0,94912.0,"7474"]
["Reactome","R-HSA-450385","Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA",0.8379945245750153,0.9679424859847289,17.0,1.0,85575.58823529411,"677"]
["Reactome","R-HSA-5656169","Termination of translesion DNA synthesis",0.8398555623780433,0.9679424859847289,34.0,2.0,72674.79411764706,"51426, 56655"]
["Reactome","R-HSA-1445148","Translocation of GLUT4 to the plasma membrane",0.8423413674103046,0.9679424859847289,80.0,6.0,97415.6,"23216, 51422, 4621, 5879, 10890, 10971"]
["Reactome","R-HSA-193368","Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol",0.8444211101947541,0.9679424859847289,24.0,2.0,113203.08333333333,"5740, 10499"]
["KEGG Pathways","hsa00480","Glutathione metabolism",0.8448697781118086,0.9675882933682725,50.0,3.0,56046.52,"2948, 2950, 4953"]
["Reactome","R-HSA-422356","Regulation of insulin secretion",0.8482102276160575,0.9679424859847289,80.0,8.0,176112.2375,"5575, 3708, 111, 152, 9254, 23236, 26251, 59345"]
["Reactome","R-HSA-159227","Transport of the SLBP independent Mature mRNA",0.849662407406031,0.9679424859847289,32.0,2.0,83103.96875,"23225, 23279"]
["Reactome","R-HSA-6807505","RNA polymerase II transcribes snRNA genes",0.8514792053974637,0.9679424859847289,71.0,4.0,60594.16901408451,"2957, 26173, 58490, 79664"]
["Reactome","R-HSA-192105","Synthesis of bile acids and bile salts",0.853249485658393,0.9679424859847289,34.0,3.0,115355.05882352941,"5740, 10499, 114883"]
["Reactome","R-HSA-168274","Export of Viral Ribonucleoproteins from Nucleus",0.8551285456757686,0.9679424859847289,31.0,2.0,87106.35483870968,"23225, 23279"]
["Reactome","R-HSA-168333","NEP/NS2 Interacts with the Cellular Export Machinery",0.8562317106544997,0.9679424859847289,30.0,2.0,89998.83333333333,"23225, 23279"]
["KEGG Pathways","hsa05150","Staphylococcus aureus infection",0.8576997952968639,0.974227918529408,52.0,3.0,68680.88461538461,"6404, 718, 728"]
["KEGG Pathways","hsa00640","Propanoate metabolism",0.8601719670918188,0.974227918529408,32.0,3.0,139453.625,"32, 219, 84532"]
["Reactome","R-HSA-73884","Base Excision Repair",0.8615942467266458,0.9679424859847289,37.0,2.0,60159.97297297297,"23583, 56655"]
["Reactome","R-HSA-73933","Resolution of Abasic Sites (AP sites)",0.8615942467266458,0.9679424859847289,37.0,2.0,60159.97297297297,"23583, 56655"]
["Reactome","R-HSA-6809371","Formation of the cornified envelope",0.8643634343986604,0.9679424859847289,125.0,6.0,48833.808,"5046, 3713, 3892, 23254, 112802, 353137"]
["Reactome","R-HSA-1592389","Activation of Matrix Metalloproteinases",0.8679650992923718,0.9679424859847289,32.0,2.0,113272.125,"80781, 4326"]
["Reactome","R-HSA-389357","CD28 dependent PI3K/Akt signaling",0.8681672053787128,0.9679424859847289,22.0,2.0,153920.5,"5295, 8503"]
["Reactome","R-HSA-70263","Gluconeogenesis",0.8714242373214385,0.9679424859847289,32.0,2.0,74771.875,"5091, 5224"]
["KEGG Pathways","hsa00071","Fatty acid degradation",0.8757700720106839,0.9776847930658017,43.0,3.0,68056.83720930232,"219, 8310, 126129"]
["Reactome","R-HSA-5621575","CD209 (DC-SIGN) signaling",0.8766659088940597,0.9679424859847289,22.0,2.0,121182.09090909091,"4790, 5058"]
["Reactome","R-HSA-6782135","Dual incision in TC-NER",0.8785127404728665,0.9679424859847289,66.0,4.0,71226.83333333333,"2074, 7874, 51426, 56655"]
["Reactome","R-HSA-180786","Extension of Telomeres",0.8785242799846826,0.9679424859847289,30.0,2.0,90665.63333333333,"8607, 56655"]
["Reactome","R-HSA-1280218","Adaptive Immune System",0.880603681894115,0.9679424859847289,819.0,68.0,114423.85958485959,"79754, 2246, 3708, 4792, 5154, 5295, 6477, 9398, 718, 947, 948, 958, 975, 997, 1027, 1062, 1277, 1493, 1508, 1509, 1956, 2248, 2254, 2255, 2309, 2549, 3082, 3164, 3667, 3688, 3797, 3937, 4008, 4688, 4790, 5058, 5155, 5159, 5305, 5690, 5795, 5817, 5879, 6614, 7328, 7336, 8503, 9965, 9976, 10324, 10540, 10892, 11059, 23112, 23327, 51665, 55182, 55740, 57542, 63893, 80176, 114907, 127544, 136371, 140691, 283807, 390594, 100616453"]
["Reactome","R-HSA-194068","Bile acid and bile salt metabolism",0.8869857021507136,0.9679424859847289,43.0,4.0,115722.16279069768,"2172, 5740, 10499, 114883"]
["Reactome","R-HSA-5250941","Negative epigenetic regulation of rRNA expression",0.8877953703924067,0.9679424859847289,105.0,0.0,43365.09523809524,""]
["Reactome","R-HSA-912631","Regulation of signaling by CBL",0.8881539071305862,0.9679424859847289,22.0,2.0,153825.0909090909,"5295, 8503"]
["Reactome","R-HSA-1234174","Regulation of Hypoxia-inducible Factor (HIF) by oxygen",0.8890408269616924,0.9679424859847289,76.0,5.0,77504.6447368421,"2034, 3091, 84962, 768, 5690"]
["Reactome","R-HSA-2262749","Cellular response to hypoxia",0.8890408269616924,0.9679424859847289,76.0,5.0,77504.6447368421,"2034, 3091, 84962, 768, 5690"]
["Reactome","R-HSA-427413","NoRC negatively regulates rRNA expression",0.8893519375849441,0.9679424859847289,102.0,0.0,43298.490196078434,""]
["Reactome","R-HSA-168271","Transport of Ribonucleoproteins into the Host Nucleus",0.8894826714732317,0.9679424859847289,30.0,2.0,86004.53333333334,"23225, 23279"]
["Reactome","R-HSA-5693616","Presynaptic phase of homologous DNA pairing and strand exchange",0.890410932566072,0.9679424859847289,40.0,0.0,115091.85,""]
["Reactome","R-HSA-425397","Transport of vitamins, nucleosides, and related molecules",0.8906724797938869,0.9679424859847289,40.0,0.0,122560.7,""]
["Reactome","R-HSA-5674135","MAP2K and MAPK activation",0.8909975905896412,0.9679424859847289,40.0,0.0,103229.325,""]
["Reactome","R-HSA-6802946","Signaling by moderate kinase activity BRAF mutants",0.8910284795082627,0.9679424859847289,40.0,0.0,107004.575,""]
["Reactome","R-HSA-6802955","Paradoxical activation of RAF signaling by kinase inactive BRAF",0.8910284795082627,0.9679424859847289,40.0,0.0,107004.575,""]
["KEGG Pathways","hsa00910","Nitrogen metabolism",0.8914473813168706,0.9776847930658017,23.0,2.0,157958.60869565216,"1491, 768"]
["Reactome","R-HSA-420499","Class C/3 (Metabotropic glutamate/pheromone receptors)",0.8928197620776894,0.9679424859847289,39.0,0.0,148886.07692307694,""]
["Reactome","R-HSA-5685938","HDR through Single Strand Annealing (SSA)",0.8928883742090238,0.9679424859847289,38.0,0.0,122597.57894736843,""]
["Reactome","R-HSA-611105","Respiratory electron transport",0.893842475468309,0.9679424859847289,90.0,0.0,65138.444444444445,""]
["Reactome","R-HSA-6802948","Signaling by high-kinase activity BRAF mutants",0.8963570885560906,0.9679424859847289,36.0,0.0,110750.05555555556,""]
["Reactome","R-HSA-1433559","Regulation of KIT signaling",0.8966204139247576,0.9679424859847289,15.0,0.0,212140.06666666668,""]
["Reactome","R-HSA-400508","Incretin synthesis, secretion, and inactivation",0.8975027743250393,0.9679424859847289,23.0,2.0,167602.73913043478,"1499, 1803"]
["Reactome","R-HSA-176187","Activation of ATR in response to replication stress",0.8976411371168849,0.9679424859847289,37.0,0.0,75973.48648648648,""]
["Reactome","R-HSA-5693537","Resolution of D-Loop Structures",0.8981093977419778,0.9679424859847289,34.0,0.0,123154.44117647059,""]
["Reactome","R-HSA-532668","N-glycan trimming in the ER and Calnexin/Calreticulin cycle",0.8988514606767475,0.9679424859847289,35.0,0.0,123078.0,""]
["Reactome","R-HSA-68884","Mitotic Telophase/Cytokinesis",0.8993713801739429,0.9679424859847289,15.0,0.0,114662.0,""]
["Reactome","R-HSA-5693568","Resolution of D-loop Structures through Holliday Junction Intermediates",0.8994607222694054,0.9679424859847289,33.0,0.0,126239.87878787878,""]
["Reactome","R-HSA-113510","E2F mediated regulation of DNA replication",0.900129731994967,0.9679424859847289,34.0,0.0,104821.5294117647,""]
["Reactome","R-HSA-5682910","LGI-ADAM interactions",0.900582120353741,0.9679424859847289,15.0,0.0,88424.86666666667,""]
["Reactome","R-HSA-6781823","Formation of TC-NER Pre-Incision Complex",0.9007672336138239,0.9679424859847289,54.0,3.0,59106.27777777778,"2074, 7874, 10920"]
["Reactome","R-HSA-73777","RNA Polymerase I Chain Elongation",0.9008176374994019,0.9679424859847289,86.0,0.0,28876.45348837209,""]
["Reactome","R-HSA-1632852","Macroautophagy",0.9009197092529801,0.9679424859847289,66.0,5.0,94645.04545454546,"51422, 57521, 22863, 55054, 84971"]
["Reactome","R-HSA-3238698","WNT ligand biogenesis and trafficking",0.9010383955264748,0.9679424859847289,26.0,2.0,87913.03846153847,"7474, 7477"]
["Reactome","R-HSA-69183","Processive synthesis on the lagging strand",0.9011586377007581,0.9679424859847289,15.0,0.0,97076.2,""]
["Reactome","R-HSA-167287","HIV elongation arrest and recovery",0.9012380978347649,0.9679424859847289,37.0,0.0,33325.48648648649,""]
["Reactome","R-HSA-167290","Pausing and recovery of HIV elongation",0.9012380978347649,0.9679424859847289,37.0,0.0,33325.48648648649,""]
["Reactome","R-HSA-5358508","Mismatch Repair",0.9014469026783581,0.9679424859847289,15.0,0.0,72705.86666666667,""]
["Reactome","R-HSA-69298","Association of licensing factors with the pre-replicative complex",0.9015562158591115,0.9679424859847289,15.0,0.0,80685.33333333333,""]
["Reactome","R-HSA-1461957","Beta defensins",0.9018330653375529,0.9679424859847289,36.0,0.0,53181.63888888889,""]
["Reactome","R-HSA-3371568","Attenuation phase",0.9019338048132877,0.9679424859847289,15.0,0.0,61699.4,""]
["Reactome","R-HSA-205043","NRIF signals cell death from the nucleus",0.9020454797448751,0.9679424859847289,15.0,0.0,68251.73333333334,""]
["Reactome","R-HSA-192456","Digestion of dietary lipid",0.902229753653296,0.9679424859847289,15.0,0.0,76231.0,""]
["Reactome","R-HSA-1834941","STING mediated induction of host immune responses",0.9025614765019172,0.9679424859847289,16.0,0.0,49227.9375,""]
["KEGG Pathways","hsa05143","African trypanosomiasis",0.9026403480905613,0.9776847930658017,35.0,3.0,130692.85714285714,"356, 3553, 23236"]
["Reactome","R-HSA-113418","Formation of the Early Elongation Complex",0.9032537534545624,0.9679424859847289,34.0,0.0,47662.26470588235,""]
["Reactome","R-HSA-167158","Formation of the HIV-1 Early Elongation Complex",0.9032537534545624,0.9679424859847289,34.0,0.0,47662.26470588235,""]
["Reactome","R-HSA-162710","Synthesis of glycosylphosphatidylinositol (GPI)",0.9038968740242452,0.9679424859847289,16.0,0.0,39677.5625,""]
["Reactome","R-HSA-975110","TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling",0.9039013483645275,0.9679424859847289,16.0,0.0,40078.9375,""]
["Reactome","R-HSA-167238","Pausing and recovery of Tat-mediated HIV elongation",0.9039743333688024,0.9679424859847289,35.0,0.0,32470.6,""]
["Reactome","R-HSA-167243","Tat-mediated HIV elongation arrest and recovery",0.9039743333688024,0.9679424859847289,35.0,0.0,32470.6,""]
["Reactome","R-HSA-3134975","Regulation of innate immune responses to cytosolic DNA",0.9040251571685332,0.9679424859847289,15.0,0.0,57934.333333333336,""]
["Reactome","R-HSA-196071","Metabolism of steroid hormones",0.9042454864626354,0.9679424859847289,32.0,0.0,79868.0625,""]
["Reactome","R-HSA-69190","DNA strand elongation",0.9048152960741793,0.9679424859847289,32.0,0.0,83566.84375,""]
["Reactome","R-HSA-73863","RNA Polymerase I Transcription Termination",0.9048215095322987,0.9679424859847289,32.0,0.0,53225.0625,""]
["Reactome","R-HSA-211935","Fatty acids",0.9055525730135272,0.9679424859847289,15.0,0.0,53745.26666666667,""]
["Reactome","R-HSA-73772","RNA Polymerase I Promoter Escape",0.9060277013574048,0.9679424859847289,31.0,0.0,54637.48387096774,""]
["Reactome","R-HSA-264876","Insulin processing",0.9060820938183253,0.9679424859847289,28.0,0.0,192360.9642857143,""]
["Reactome","R-HSA-70268","Pyruvate metabolism",0.9066149500262275,0.9679424859847289,27.0,2.0,79341.18518518518,"5164, 9123"]
["Reactome","R-HSA-75067","Processing of Capped Intronless Pre-mRNA",0.9083101277205488,0.9679424859847289,30.0,0.0,54769.13333333333,""]
["Reactome","R-HSA-1483191","Synthesis of PC",0.9088152524211646,0.9679424859847289,28.0,0.0,129732.71428571429,""]
["KEGG Pathways","hsa04744","Phototransduction",0.9088858019074469,0.9776847930658017,28.0,2.0,75493.21428571429,"8787, 131890"]
["Reactome","R-HSA-72086","mRNA Capping",0.9089752287933769,0.9679424859847289,29.0,0.0,63703.96551724138,""]
["Reactome","R-HSA-5693554","Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)",0.9090093291465204,0.9679424859847289,27.0,0.0,124846.5925925926,""]
["Reactome","R-HSA-5668914","Diseases of metabolism",0.9090431213811353,0.9679424859847289,44.0,4.0,141951.29545454544,"5091, 8029, 64087, 81693"]
["Reactome","R-HSA-381042","PERK regulates gene expression",0.9104103046364532,0.9679424859847289,29.0,0.0,57052.41379310345,""]
["Reactome","R-HSA-167160","RNA Pol II CTD phosphorylation and interaction with CE during HIV infection",0.9118662692022506,0.9679424859847289,27.0,0.0,66906.18518518518,""]
["Reactome","R-HSA-77075","RNA Pol II CTD phosphorylation and interaction with CE",0.9118662692022506,0.9679424859847289,27.0,0.0,66906.18518518518,""]
["Reactome","R-HSA-901042","Calnexin/calreticulin cycle",0.9131321068669934,0.9679424859847289,26.0,0.0,134960.46153846153,""]
["Reactome","R-HSA-5673000","RAF activation",0.9145201878022051,0.9679424859847289,25.0,0.0,94751.56,""]
["Reactome","R-HSA-380994","ATF4 activates genes",0.9149049271390779,0.9679424859847289,26.0,0.0,58243.88461538462,""]
["Reactome","R-HSA-4570464","SUMOylation of RNA binding proteins",0.9149969526170537,0.9679424859847289,47.0,3.0,73907.08510638298,"22955, 23225, 23279"]
["Reactome","R-HSA-156711","Polo-like kinase mediated events",0.9155832375042382,0.9679424859847289,17.0,1.0,59721.117647058825,"7465"]
["Reactome","R-HSA-5621480","Dectin-2 family",0.9160434650812732,0.9679424859847289,24.0,0.0,100222.29166666667,""]
["Reactome","R-HSA-170822","Regulation of Glucokinase by Glucokinase Regulatory Protein",0.9166254841152551,0.9679424859847289,30.0,2.0,83820.36666666667,"23225, 23279"]
["Reactome","R-HSA-212676","Dopamine Neurotransmitter Release Cycle",0.9169956949080298,0.9679424859847289,22.0,0.0,222015.72727272726,""]
["Reactome","R-HSA-156588","Glucuronidation",0.9170756879857273,0.9679424859847289,24.0,0.0,77918.5,""]
["Reactome","R-HSA-427359","SIRT1 negatively regulates rRNA Expression",0.9172357011720584,0.9679424859847289,64.0,0.0,18487.640625,""]
["KEGG Pathways","hsa03060","Protein export",0.9172755821178961,0.9776847930658017,23.0,0.0,89071.26086956522,""]
["Reactome","R-HSA-983170","Antigen Presentation: Folding, assembly and peptide loading of class I MHC",0.9175041789421188,0.9679424859847289,25.0,0.0,47595.52,""]
["KEGG Pathways","hsa00563","Glycosylphosphatidylinositol(GPI)-anchor biosynthesis",0.918697400765061,0.9776847930658017,24.0,0.0,52845.375,""]
["Reactome","R-HSA-171052","LDL-mediated lipid transport",0.9196252702229054,0.9679424859847289,23.0,0.0,114602.08695652174,""]
["Reactome","R-HSA-77289","Mitochondrial Fatty Acid Beta-Oxidation",0.9198396135221848,0.9679424859847289,22.0,0.0,96163.18181818182,""]
["Reactome","R-HSA-5620916","VxPx cargo-targeting to cilium",0.9200091098306432,0.9679424859847289,21.0,0.0,159966.38095238095,""]
["Reactome","R-HSA-6803204","TP53 Regulates Transcription of Genes Involved in Cytochrome C Release",0.9201350840694723,0.9679424859847289,21.0,0.0,103038.90476190476,""]
["Reactome","R-HSA-164938","Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters",0.9204573191008806,0.9679424859847289,22.0,0.0,78568.13636363637,""]
["Reactome","R-HSA-381426","Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",0.9205033831458024,0.9679424859847289,21.0,0.0,128492.57142857143,""]
["Reactome","R-HSA-73728","RNA Polymerase I Promoter Opening",0.9205938129768679,0.9679424859847289,58.0,0.0,26441.327586206895,""]
["Reactome","R-HSA-167242","Abortive elongation of HIV-1 transcript in the absence of Tat",0.9206443865816788,0.9679424859847289,24.0,0.0,29121.708333333332,""]
["Reactome","R-HSA-174048","APC/C:Cdc20 mediated degradation of Cyclin B",0.9212119139533953,0.9679424859847289,22.0,0.0,69272.04545454546,""]
["Reactome","R-HSA-901032","ER Quality Control Compartment (ERQC)",0.9216613072054807,0.9679424859847289,21.0,0.0,163700.42857142858,""]
["Reactome","R-HSA-163200","Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.",0.9226173101549533,0.9679424859847289,111.0,0.0,62203.207207207204,""]
["Reactome","R-HSA-77595","Processing of Intronless Pre-mRNAs",0.9226960045654203,0.9679424859847289,21.0,0.0,61920.0,""]
["Reactome","R-HSA-422085","Synthesis, secretion, and deacylation of Ghrelin",0.9229311952613123,0.9679424859847289,19.0,0.0,173041.8947368421,""]
["Reactome","R-HSA-6799198","Complex I biogenesis",0.9231334184317279,0.9679424859847289,48.0,0.0,51514.645833333336,""]
["Reactome","R-HSA-167152","Formation of HIV elongation complex in the absence of HIV Tat",0.9233533288391994,0.9679424859847289,49.0,0.0,44807.897959183676,""]
["Reactome","R-HSA-69186","Lagging Strand Synthesis",0.9234748803686833,0.9679424859847289,20.0,0.0,107167.95,""]
["Reactome","R-HSA-6788467","IL-6-type cytokine receptor ligand interactions",0.9235065415669265,0.9679424859847289,20.0,0.0,80118.65,""]
["Reactome","R-HSA-198753","ERK/MAPK targets",0.9238147076635691,0.9679424859847289,22.0,2.0,163393.72727272726,"6196, 4208"]
["Reactome","R-HSA-5625886","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3",0.9240777707925699,0.9679424859847289,62.0,2.0,46260.75806451613,"10499, 23081"]
["Reactome","R-HSA-888590","GABA synthesis, release, reuptake and degradation",0.9242645103170195,0.9679424859847289,19.0,0.0,162212.84210526315,""]
["Reactome","R-HSA-6804760","Regulation of TP53 Activity through Methylation",0.9243455777225655,0.9679424859847289,20.0,0.0,78688.8,""]
["Reactome","R-HSA-167169","HIV Transcription Elongation",0.9248703652146292,0.9679424859847289,47.0,0.0,44659.89361702128,""]
["Reactome","R-HSA-167200","Formation of HIV-1 elongation complex containing HIV-1 Tat",0.9248703652146292,0.9679424859847289,47.0,0.0,44659.89361702128,""]
["Reactome","R-HSA-167246","Tat-mediated elongation of the HIV-1 transcript",0.9248703652146292,0.9679424859847289,47.0,0.0,44659.89361702128,""]
["KEGG Pathways","hsa00630","Glyoxylate and dicarboxylate metabolism",0.9250021813834141,0.9776847930658017,18.0,0.0,207030.27777777778,""]
["Reactome","R-HSA-5693579","Homologous DNA Pairing and Strand Exchange",0.9250202908335934,0.9679424859847289,43.0,0.0,108464.06976744186,""]
["Reactome","R-HSA-181430","Norepinephrine Neurotransmitter Release Cycle",0.9250240276384551,0.9679424859847289,18.0,0.0,227701.44444444444,""]
["Reactome","R-HSA-71403","Citric acid cycle (TCA cycle)",0.9258770313265714,0.9679424859847289,19.0,0.0,103279.78947368421,""]
["Reactome","R-HSA-389948","PD-1 signaling",0.9259363252861152,0.9679424859847289,21.0,0.0,42924.04761904762,""]
["Reactome","R-HSA-110320","Translesion Synthesis by POLH",0.9259752020236953,0.9679424859847289,19.0,0.0,86572.73684210527,""]
["Reactome","R-HSA-156584","Cytosolic sulfonation of small molecules",0.9264290375241201,0.9679424859847289,19.0,0.0,70139.21052631579,""]
["Reactome","R-HSA-5635838","Activation of SMO",0.9264886292000688,0.9679424859847289,18.0,0.0,106701.61111111111,""]
["Reactome","R-HSA-171306","Packaging Of Telomere Ends",0.9265141834348745,0.9679424859847289,47.0,0.0,46129.17021276596,""]
["Reactome","R-HSA-6804114","TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest",0.9269073019683585,0.9679424859847289,19.0,0.0,63995.84210526316,""]
["Reactome","R-HSA-264642","Acetylcholine Neurotransmitter Release Cycle",0.9269301100601516,0.9679424859847289,17.0,0.0,206433.88235294117,""]
["Reactome","R-HSA-435354","Zinc transporters",0.9269496938832038,0.9679424859847289,17.0,0.0,187181.4705882353,""]
["Reactome","R-HSA-181429","Serotonin Neurotransmitter Release Cycle",0.9270150922540954,0.9679424859847289,17.0,0.0,226067.29411764705,""]
["KEGG Pathways","hsa00100","Steroid biosynthesis",0.9270267409159151,0.9776847930658017,19.0,0.0,60550.21052631579,""]
["Reactome","R-HSA-5663220","RHO GTPases Activate Formins",0.9270287911681555,0.9679424859847289,132.0,11.0,130610.26515151515,"8379, 91010, 752, 1062, 3688, 4085, 5879, 23279, 55839, 55920, 147841"]
["Reactome","R-HSA-936964","Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon",0.9270715372826734,0.9679424859847289,18.0,0.0,133929.11111111112,""]
["Reactome","R-HSA-5423646","Aflatoxin activation and detoxification",0.9274830513797414,0.9679424859847289,19.0,0.0,59041.78947368421,""]
["Reactome","R-HSA-190872","Transport of connexons to the plasma membrane",0.927693266795451,0.9679424859847289,19.0,0.0,70260.42105263157,""]
["Reactome","R-HSA-1461973","Defensins",0.9279882505873932,0.9679424859847289,44.0,0.0,51663.22727272727,""]
["Reactome","R-HSA-69205","G1/S-Specific Transcription",0.928140966416303,0.9679424859847289,18.0,0.0,76730.55555555556,""]
["Reactome","R-HSA-8876725","Protein methylation",0.9282736493989923,0.9679424859847289,18.0,0.0,77614.33333333333,""]
["Reactome","R-HSA-937072","TRAF6 mediated induction of TAK1 complex",0.9283067539616521,0.9679424859847289,17.0,0.0,169556.4705882353,""]
["Reactome","R-HSA-176412","Phosphorylation of the APC/C",0.9283891351936785,0.9679424859847289,18.0,0.0,76328.22222222222,""]
["Reactome","R-HSA-5656121","Translesion synthesis by POLI",0.9288045093795579,0.9679424859847289,17.0,0.0,109285.82352941176,""]
["Reactome","R-HSA-1482925","Acyl chain remodelling of PG",0.9290000053031454,0.9679424859847289,18.0,0.0,158806.27777777778,""]
["Reactome","R-HSA-450604","KSRP (KHSRP) binds and destabilizes mRNA",0.9293983957640853,0.9679424859847289,18.0,0.0,53346.72222222222,""]
["Reactome","R-HSA-190840","Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane",0.9294667440743585,0.9679424859847289,18.0,0.0,72214.11111111111,""]
["Reactome","R-HSA-392517","Rap1 signalling",0.9300260459725987,0.9679424859847289,16.0,0.0,147241.625,""]
["Reactome","R-HSA-975163","IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation",0.93026547410726,0.9679424859847289,16.0,0.0,178493.0625,""]
["Reactome","R-HSA-1369062","ABC transporters in lipid homeostasis",0.9304242117449052,0.9679424859847289,17.0,0.0,76938.17647058824,""]
["Reactome","R-HSA-110312","Translesion synthesis by REV1",0.9307486197359803,0.9679424859847289,16.0,0.0,111643.0,""]
["KEGG Pathways","hsa05110","Vibrio cholerae infection",0.9309005209618229,0.9776847930658017,53.0,5.0,128644.2641509434,"109, 115, 7082, 9114, 245972"]
["Reactome","R-HSA-1482922","Acyl chain remodelling of PI",0.9310025010843923,0.9679424859847289,17.0,0.0,165465.76470588235,""]
["Reactome","R-HSA-2559584","Formation of Senescence-Associated Heterochromatin Foci (SAHF)",0.9313371216480664,0.9679424859847289,16.0,0.0,89648.5,""]
["Reactome","R-HSA-418038","Nucleotide-like (purinergic) receptors",0.931894609607117,0.9679424859847289,16.0,0.0,80856.6875,""]
["Reactome","R-HSA-5668541","TNFR2 non-canonical NF-kB pathway",0.9319257868192474,0.9679424859847289,100.0,7.0,81732.41,"958, 4982, 5690, 7133, 7186, 8995, 9966"]
["KEGG Pathways","hsa00120","Primary bile acid biosynthesis",0.9323188295778577,0.9776847930658017,16.0,0.0,81257.9375,""]
["Reactome","R-HSA-450513","Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA",0.932473761400356,0.9679424859847289,16.0,0.0,67897.9375,""]
["Reactome","R-HSA-156581","Methylation",0.9325502412688335,0.9679424859847289,15.0,0.0,202127.8,""]
["Reactome","R-HSA-1295596","Spry regulation of FGF signaling",0.9325800974187277,0.9679424859847289,16.0,0.0,200119.875,""]
["KEGG Pathways","hsa00270","Cysteine and methionine metabolism",0.9332672320314965,0.9776847930658017,36.0,3.0,143214.41666666666,"1491, 1787, 1788"]
["Reactome","R-HSA-918233","TRAF3-dependent IRF activation pathway",0.9333539275606918,0.9679424859847289,16.0,0.0,64438.9375,""]
["Reactome","R-HSA-202430","Translocation of ZAP-70 to Immunological synapse",0.9335917368590094,0.9679424859847289,17.0,0.0,41395.17647058824,""]
["Reactome","R-HSA-163210","Formation of ATP by chemiosmotic coupling",0.9337197248727176,0.9679424859847289,16.0,0.0,51448.3125,""]
["Reactome","R-HSA-8856825","Cargo recognition for clathrin-mediated endocytosis",0.934023980314055,0.9679424859847289,98.0,9.0,141407.75510204083,"154, 1956, 3267, 7474, 8301, 9146, 10618, 10920, 90019"]
["Reactome","R-HSA-429958","mRNA decay by 3' to 5' exoribonuclease",0.9348121696281748,0.9679424859847289,16.0,0.0,38642.8125,""]
["KEGG Pathways","hsa00900","Terpenoid backbone biosynthesis",0.9349951504153885,0.9776847930658017,15.0,0.0,64730.26666666667,""]
["KEGG Pathways","hsa03440","Homologous recombination",0.9400193869477574,0.9776847930658017,28.0,0.0,145375.07142857142,""]
["Reactome","R-HSA-388396","GPCR downstream signaling",0.9460885729306041,0.9780157387025395,952.0,77.0,118254.52205882352,"8874, 29, 109, 115, 623, 1607, 1909, 1910, 2852, 3708, 5295, 5999, 7434, 8527, 9828, 26686, 27237, 55160, 108, 111, 152, 153, 154, 624, 718, 728, 747, 885, 886, 1236, 1325, 1437, 1814, 1902, 2768, 2867, 3274, 3357, 3363, 5136, 5138, 5364, 5368, 5734, 5739, 5879, 5996, 5998, 6000, 6003, 6004, 6352, 6363, 6387, 6655, 6865, 7204, 8490, 8503, 8620, 8787, 9138, 9181, 10276, 10636, 11214, 11343, 23236, 23263, 26230, 27115, 53831, 57580, 59345, 81285, 122876, 339403"]
["KEGG Pathways","hsa03410","Base excision repair",0.9519049183318389,0.9776847930658017,33.0,2.0,55952.030303030304,"23583, 56655"]
["Reactome","R-HSA-166658","Complement cascade",0.9578825815825819,0.9889886061993993,44.0,3.0,135392.3409090909,"718, 728, 966"]
["Reactome","R-HSA-1187000","Fertilization",0.960460019452394,0.9893949036742585,26.0,2.0,137087.15384615384,"928, 79820"]
["Reactome","R-HSA-1474165","Reproduction",0.960460019452394,0.9893949036742585,26.0,2.0,137087.15384615384,"928, 79820"]
["KEGG Pathways","hsa04115","p53 signaling pathway",0.9633772107282533,0.9776847930658017,68.0,7.0,138139.23529411765,"595, 3732, 6477, 1021, 4616, 7057, 8795"]
["Reactome","R-HSA-6781827","Transcription-Coupled Nucleotide Excision Repair (TC-NER)",0.9662316227444374,0.9893949036742585,79.0,5.0,70071.74683544303,"2074, 7874, 10920, 51426, 56655"]
["Reactome","R-HSA-392451","G beta:gamma signalling through PI3Kgamma",0.9668043631552203,0.9893949036742585,48.0,4.0,104847.27083333333,"5295, 1437, 8503, 59345"]
["Reactome","R-HSA-8851708","Signaling by FGFR2 IIIa TM",0.9750539871419488,0.9933996238541223,19.0,1.0,70452.15789473684,"2246"]
["Reactome","R-HSA-8876384","Listeria monocytogenes entry into host cells",0.9768582795161257,0.9933996238541223,20.0,2.0,147208.35,"1499, 9146"]
["Reactome","R-HSA-201451","Signaling by BMP",0.9801927197327815,0.9952502565086981,24.0,3.0,215400.58333333334,"4092, 6497, 64388"]
["Reactome","R-HSA-937039","IRAK1 recruits IKK complex",0.9819191096190131,0.9952502565086981,15.0,1.0,71254.13333333333,"57161"]
["Reactome","R-HSA-975144","IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation",0.9819191096190131,0.9952502565086981,15.0,1.0,71254.13333333333,"57161"]
["Reactome","R-HSA-6782210","Gap-filling DNA repair synthesis and ligation in TC-NER",0.9827391719229122,0.9952502565086981,65.0,4.0,62132.015384615384,"2074, 7874, 51426, 56655"]
["Reactome","R-HSA-8852135","Protein ubiquitination",0.9832814745155316,0.9952502565086981,62.0,4.0,74501.59677419355,"997, 7328, 7874, 51255"]
["Reactome","R-HSA-168638","NOD1/2 Signaling Pathway",0.9850856915968575,0.9958181359357222,36.0,3.0,120285.19444444444,"1540, 5608, 7128"]
["Reactome","R-HSA-2129379","Molecules associated with elastic fibres",0.9890056992814164,0.9958181359357222,37.0,4.0,165691.37837837837,"7042, 2006, 3688, 4052"]
["KEGG Pathways","hsa04514","Cell adhesion molecules (CAMs)",0.9915013588545936,0.9959799374495548,131.0,13.0,208425.80916030533,"6404, 23114, 214, 947, 958, 1000, 1493, 3688, 5817, 6383, 6614, 22871, 49861"]
["Reactome","R-HSA-5654706","FRS-mediated FGFR3 signaling",0.9930756960664274,0.9958181359357222,20.0,2.0,133712.0,"2246, 2254"]
["Reactome","R-HSA-909733","Interferon alpha/beta signaling",0.9952343906187999,0.996155903943447,67.0,4.0,53245.40298507463,"684, 3394, 3662, 6772"]