The PDF file includes:

• Fig. S1. shRNA-mediated knockdown of DDR2 expression.
• Fig. S2. Histological comparison of lungs from B16F10 tumor–bearing mice.
• Fig. S3. Spleen from NA13 tumor–bearing mice analyzed using CyTOF with PhenoGraph algorithm.
• Fig. S4. Analysis of PD-1 expression on tumor-infiltrating T cells.
• Fig. S5. Spleen from MC38 tumor–bearing mice analyzed using CyTOF with PhenoGraph algorithm.
• Fig. S6. Quantification of immune cell populations in bladder cancer patients with varying DDR2 expression levels.
• Table S4. CyTOF antibody panel used for the analysis of spleen and tumors from mice implanted with the NA13 cell line.
• Table S5. CyTOF antibody panel used for the analysis of tumors from mice implanted with the MC38 cell line.

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Other Supplementary Material for this manuscript includes the following:

• Table S1 (Microsoft Excel format). NA13 mutation analysis.
• Table S2 (Microsoft Excel format). Gene set enrichment analysis.
• Table S3 (Microsoft Excel format). Thirty-four–gene shRNA library.