{"text_format":"2","workbook":"xlsx","n_sheets":1,"sheets":["Sheet1"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":31,"n_cols":9,"rows_kept":31,"cut":false,"hidden":false,"merged":[[0,0,0,8]]}
["Suppoting Information Table 5:The value of statistical power under different model for a variant with different MAF "]
["                PMID","Gene(variant) ","Comparison","No.of studies","The sample size is more than 4000","MAF","power","the value of power if the MAF is 0.2","the value of power if the MAF is 0.1"]
["CYP1A1"]
[25048966,"CYP1A1(T6235C)","Dominant ",16,"4389(1663/2726)",0.3239,0.873,0.8568,70.67]
["MicroRNA 423"]
[26925372,"MicroRNA-423(rs6505162)","Additive",4,"5043(2048/2995)",0.3419,0.9885,0.9501,77.79]
["CTLA"]
[26770356,"CTLA-4(49G>A)","Dominant ",4,"4071(1944/2127)",0.3155,0.8752,0.8568,0.7067]
["ZBTB20"]
[28164573,"ZBTB20(rs9841504)","Dominant ",2,"4602(2184/2418)",0.1435,0.8012,0.8568,0.7067]
["EPHX1 His139Arg"]
[25714851,"EPHX1(rs2234922)","Additive",7,"5792(2066/3726)","0.2155a",0.9593,0.9501,0.7779]
["EPHX1  Tyr113His"]
[25714851,"EPHX1(rs1051740)","Additive",8,"5792(2066/3726)",0.3133,0.9856,0.9501,0.7779]
["MicroRNA 196"]
[26925372,"MicroRNA-196a2(rs11614913)","Additive",6,"4618(2071/2547)",0.4503,0.9928,0.9501,0.7779]
["XPA"]
[25709470,"XPA A23G(rs1800975)","Dominant ",9,"5617(2065/3552)",0.4944,0.7636,0.8568,0.7067]
["XRCC1 Arg399Gln"]
[23543084,"XRCC1(rs25487)","Dominant ",18,"10517(3296/7221)",0.3434,0.868,0.8568,0.7067]
[]
["                PMID","Gene(variant) ","Comparison","No.of studies","The sample size is less  than 4000","MAF","power","the value of power if the MAF is 0.2","the value of power if the MAF is 0.1"]
["Fas"]
[24598538,"Fas(rs1800682)","Dominant ",4,"3012(1277/1735)",0.4543,0.6855,0.7473,0.5842]
["MicroRNA 146"]
[26925372,"MicroRNA-146a(rs2910164)","Additive",4,"3032(1494/1538)",0.5782,96.51,0.881,0.66]
["MMP3"]
[23644699,"MMP3(rs3025058)","Recessive",3,"1940(856/1084)",0.6153,0.5663,0.1425,0.0733]
["XRCC1 Arg280His"]
[23543084,"XRCC1(rs25489)","Dominant ",4,"3011(1152/1859)",0.1245,0.6463,0.7472,0.5841]
["aThe MAF is obtained from dbSNP database"]