>MULE1_EI ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VVVDDTCG---TNEFGLP -----LVVA---VNI-----------------------------------------DKEK -----------------------RSHCVFFALMTNRTTQSFV------------------ --------LVF-SYVK-------------------------------------------- -----------------------------KFYD-----------LTVVICDRCLSQTNAL LQVFK------------------------------------------------------- ------------------------------------------------------------ ----DVNLVFCTRHIRRNLIT--EFGKYHPLV---------------------------- -------------------------------NLFNKVVFGKEGTE-------EQLIVAMK NQIIQDE------------TSKIE------------------------------------ ------------------E--NFYDDKNTE-LD----------GNHIMDCVKETLETLIE CTNKSNIKNSSPTK---------CRMFREL------------------------------ ---------LDC-----------------------AKCWLPSSM---------------- -----------------------MTKTTNSTSNGIEGFFGWLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR1_TP ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ISGDDTEG---INCEKRP -----LYTL---LGK-----------------------------------------DQNE -----------------------KTFPIAWAFMPSKSFWAYE------------------ --------WFFSMAMP--ALHP-------------------------------------- ---------------------------GDAIKR-----------VQLIVTDADNQETGAV EKLVGGNLKPSKAEDRLYT----------------------------------------- ------------------------------------------------------------ ----KAWHRWCAWHRINCNFT---------QD---------------------------- -------------------------------SKYKPLLTKIKNRCVLSKIEMDMLERWLW YFIKEYE------------SSDEV------------------------------------ ------------------Q--FCMALLKAYLNN----------ANQSSHIGEVDEKDRKI ILEFIT-----------------TSFNARSH----------------------------- ---------KLF-----------------------ESEFDDD------------------ -----------------------CMDLGNTTTSASEGYHRGIK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR1_SM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LNADATYK---LVWQGYP -----ILII---GTT-----------------------------------------DLDR -----------------------HFHSFGLGICTNEKTADFN------------------ --------FIF-SSINIGLKKI-------------------------------------- ---------------------------NASLFN-----------PRVLISDASNAIRKAY SQVFN------------------------------------------------------- ------------------------------------------------------------ ----KNEIVMCWAHMRRNCVK--------------------------------------- --------------------------------KIESLVAKEDQ---------NELIEDVD QLQLSQS------------QVIFE------------------------------------ ------------------K--ASSLFVKKWRQ---------------------------- --------------------KKATEFLDYMNMMW-------------------------- ---------LTT-----------------------HNTWYEGYM---------------- -------------------------PFTPSTNNNLESNNRVLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-3_TV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------HFIDATHS---LLEFKML -----FYMI---SAK-----------------------------------------FPNT -----------------------HAFPIFQFVVYPNTSENIA------------------ --------FCL-KAFF--NWAK-------------------------------------- ---------------------------VK---------------PKYFMSDCAQEIENAI INSFP------------------------------------------------------- ------------------------------------------------------------ ----EVILHWCAVHVMRAFRK--------------------------------------- --------------------------------NLKDYAFESSDK--------LILDTKMN YLAYGRNGK----------KEWIE------------------------------------ ------------------P--TFKKILEIAEKF----------PEF-------------- -----------------------SKYIQNQW----------------------------- ---------ISN-----------------------QERWTAA------------------ ----------------------ERDENLALTNNISESINKKIK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-6_TV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------FHIDSTYK---LLRSNIP -----LYAF---TGK-----------------------------------------IKDF -----------------------HIFPFLYFFCQPDTYQNIQ------------------ --------VCVCAYLR----WV-------------------------------------- ---------------------------TIE--------------PEYISMDCAPQIAQAI EESIP------------------------------------------------------- ------------------------------------------------------------ ----QAQILWCGVHVLRAILR---KSNKFSSQ---------------------------- -------------------------------EKFEQFY--------------NLMKDLVF KLDAEH-------------EEEAN------------------------------------ ------------------A--AYDQVLELLDTD----------PTA-------------- -----------------------SQYFNRQW----------------------------- ---------RYN-----------------------ISRWIAR------------------ -----------------------DRREGDATNNIAEAHFRTLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDr-1_TV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LFCDGTFK---ITPKHFQ ---KGQMLTIM-ICE-----------------------------------------PSTN -----------------------QYLPLLFIFMKNRTFESYK------------------ --------KAF-EYIF---TVK-------------------------------------- ---------------------------GIQFSK-----------LIQIHCDFEKGMIEAL QQIFP------------------------------------------------------- ------------------------------------------------------------ ----KVRIIGCLFHFKQALHR--------------------------------------- --------------------------------KLVALYTKNF----------NTLQNSLF KLYSITP------------FMSHE------------------------------------ ------------------EFVLTMHIINQNKVD----------SI--------------- -----------------------KDYIDYFN----------------------------- ---------KVW-----------------------LPHYNLISQ---------------- ----------------------YNNATAIFTNDCLESMHSEFS----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR7x_AP ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VYMDGTFD---YCTRFFM -----QMFT---IHG-----------------------------------------FQNG -----------------------HYVPLIFCLLPNKLTSSYI------------------ --------FALRSICE--KCKD-------------------------------------- ---------------------------MNLIFL-----------PANVTIDYEKAIINAA TEVWP------------------------------------------------------- ------------------------------------------------------------ ----ESNIIGCRFHLTNSWWK---KIQSLGLS---------------------------- -------------------------------MEYKEKNSEI-----------GKWLRHTF GLLFLDA------------QEVSD------------------------------------ ------------------C--FSYDFMSDRPVN----------ELLTKY----------- -----------------------SDYLVDNYIGDDC------------------------ ---------SYP-----------------------PSLWA-------------------- ----------------------SLSASLTRTTNACESFHAVFK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR2x_SM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IYGDGTFD---KCPSMFY -----QLYT---WHA-----------------------------------------LVGT -----------------------SYPPCIYFLLQKKNRETYI------------------ --------RMF-EIMK--QLLT-------------------------------------- ---------------------------NLS--------------PRKVLVDFEKACMTAA AVAFP------------------------------------------------------- ------------------------------------------------------------ ----DAEVKGCYFHLCQSLVR---KVNCVGLK---------------------------- -------------------------------NLY-ESNVDV-----------KLMLKSLC ALAFVP-------------ANEVR------------------------------------ ------------------S--AFDILARTFPDE----------DPYNAVLSYFF------ -----------------------QTYIEGA-IGRDP------------------------ ---------MFP-----------------------VRIWNQWE----------------- ----------------------AAAEKSPKTTNCCEGFHNALN----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR4x_SM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IFADGTFD---TVPRIFF -----QLYT---IHG-----------------------------------------EVFG -----------------------YTFPFVYVLCLRKTRSVYE------------------ --------SII-NHLK-EASIR-------------------------------------- ---------------------------LNITFS-----------PETIMVDFEMAAIMAF KNMLP------------------------------------------------------- ------------------------------------------------------------ ----NSTVKGCLFHFNQSLWR---RIQENGLS---------------------------- -------------------------------VRYRNRQNTDLQ---------GLVVALMA -LPFIP-------------EEDVA------------------------------------ ------------------G--TFKDLVAFAPPE----------LNDFIEFYG-------- -----------------------RTYIGLIRNGDSWTS-VTPR----------------- ----------FE-----------------------NTMWSCYN----------------- ----------------------STLSGHRRTNNVVEGWHSRFH----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR1x_SM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------WFADGTFR---VSPNGYD -----QLYT---IHG-----------------------------------------FING -----------------------EVFPVVYALLSSRTEEAYQ------------------ --------HLL-QEIL--ILKA-------------------------------------- ---------------------------GLN--------------PASIMVDFELAAIRAF QSTFP------------------------------------------------------- ------------------------------------------------------------ ----TATITGCMFHFGQCVWR-------KLQA---------------------------- -------------------------------EGFSERYRNEPDF--------ALLVKRLL ALAFVPP------------QDVID------------------------------------ ---------------------LFEHLIEDPAYR----------DIEVI------------ -----------------------CDYMEDNFIGRLRRRRRGPP----------------- ---------RFS-----------------------IQLWSQFS----------------- ----------------------RVIDNLPRSNNAIEGWHNAFN----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDr-1x_AP ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ICIDGMNS---YNFNLTT -----V------LIL-----------------------------------------DDMR -----------------------EGFPCAFMISNRVDEGVLK------------------ --------ILF-SQIR--ALTG-------------------------------------- ---------------------------LIK--------------PKVFMSDMAECFFNAW LVEM-------------------------------------------------------- ------------------------------------------------------------ --KQPKFRIYCTWHVDRAWSK-------NLTK---------------------------- -------------------------------VKLKEKQAEVY----------KIIRTLLH EQDAKAF------------ENIFE------------------------------------ ------------------S--AINQMSADEQTC----------EFA-------------- -----------------------NYFVSQY------------------------------ ---------GNY-----------------------VQSWAYCH----------------- -----------------------RIHAGVNTNMHIERMHCTLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MUDR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LSVDSTAL---NGRWNGH -----LASA---TGV-----------------------------------------DGHN -----------------------WMYPVCFGFFQAETVDNWI------------------ --------WFM-KQLK--KVVG-------------------------------------- ---------------------------DMT--------------LLAICSDAQKGLMHAV NEVFP------------------------------------------------------- ------------------------------------------------------------ ----YAERRECFRHLMGNYVK--------------------------------------- --------------------------------HHAG-------------------SEHMY PAARAYR------------RDVFE------------------------------------ ------------------H--HVSKVRNVHKI---------------------------- -----------------------AEYLDQH------------------------------ -----------H-----------------------KFLWYRSGFN--------------- ----------------------KDIKCDYITNNMAEVYNNWVK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Mudr5_OS ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ICLDGCHI---KTKYGGQ -----LLTA---VGM-----------------------------------------DPND -----------------------CIYPIAFAVVEVESLATWK------------------ --------WFL-ETLK--NDLG-------------------------------------- ---------------------------IEN-TY-----------PWTIMTDKQKGLIPAV QQVFP------------------------------------------------------- ------------------------------------------------------------ ----ESEHRFCVRHLYSNFQL--------------------------------------- --------------------------------QFKG----------------EVLKNQLW ACARSSS------------VQEWN------------------------------------ ------------------K--NMDVMRNLNKSA--------------------------- -----------------------YEWLEKL------------------------------ -----------P-----------------------PNTWVRAFFS--------------- ----------------------EFPKCDILLNNNCEVFNKYIL----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-8_SBi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IGLDGCWF---KGANNGN -----LLCA---IGR-----------------------------------------DANN -----------------------QMYPIAWAAVPIESYDTWY------------------ --------WFI-GLLQ--KDLN-------------------------------------- ---------------------------ISNGGQ-----------DWVLISDQQKGLLKAV KELVP------------------------------------------------------- ------------------------------------------------------------ ----NAEHRMCARHIYANWRK--------------------------------------- --------------------------------KYTD----------------KKLQKKWW RCAKASC------------RTLFN------------------------------------ ------------------L--YRAYLAKDTP----------------------------- -----------------------EGAQDMM------------------------------ ---------STD-----------------------PQHWSRAFFR--------------- ----------------------IGSNCDSVDNNICESFNNSIM----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >ATMU3 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IGIDGAFL---KWDIKGH -----LLAA---VGR-----------------------------------------DGDN -----------------------RIVRIAWSVVEIENDDNWD------------------ --------WFL-RQLS--TSLG-------------------------------------- ---------------------------LCE-MT-----------DLAIISDKQSGLVKAI HTILP------------------------------------------------------- ------------------------------------------------------------ ----QAEHRQCSKHIMDNWKR--------------------------------------- --------------------------------DNHD----------------IELQRLFW KIARSYT------------VEEFN------------------------------------ ------------------N----------------------------------------- -------------------------YQADL------------------------------ ----------KS-----------------------PITWSRAFFR--------------- ----------------------TGTCCNDNLNNLSESFNRTIR----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-12_VV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IAIDSAHM---SGPYGGA -----LFSA---TAY-----------------------------------------DAND -----------------------SMFPLAFGVMSSENYEDWL------------------ --------WFL-EKLK--IVVG-------------------------------------- ---------------------------NKE---------------VIIISDRHPALLRSV PEVFG------------------------------------------------------- ------------------------------------------------------------ ----LENHAYCYRHLKENFSS---------FL---------------------------- -------------------------------SKHNTRGNKGK----------ENALQFLD SIAYGRL------------EHDYN------------------------------------ ------------------V--SMFELKKYNEAL--------------------------- -----------------------ATWVEEN------------------------------ -----------A-----------------------PHHWAMSKFP--------------- -----------------------KQRWDKMTTNLAESFNAWLR----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR4_SM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ITIDGTFL---AGVNKGT -----LLVA---VAQ-----------------------------------------DGKD -----------------------QLVLLAYAIVESENRSSWL------------------ --------YFL-ENLN--RHFD-------------------------------------- ---------------------------IND--S-----------STIIMSDRDVGLLSAV NSVAP------------------------------------------------------- ------------------------------------------------------------ ----RAIKCNCVRHIAMNLKS--------------------------------------- --------------------------------RFHN----------------ILLMEKYW YLVYTYD------------EIAFE------------------------------------ ------------------R--GMRELQVLNE----------------------------- -----------------------EFYHELV------------------------------ ---------NMG-----------------------ISSWANSKCP--------------- -----------------------IAKYGKNTSNAAESMNSAIK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-6_VV ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IQIDGTFL---YGKYMGK -----LLIA---TSI-----------------------------------------DGNG -----------------------HVFPLAFAIVEEESQDSWS------------------ --------WFL-IALR--HHVT-------------------------------------- ---------------------------QRE--------------GICLISDRHAGINAAV RNPSVGWSPP-------------------------------------------------- ------------------------------------------------------------ ----HAQHRYCLRHVVSNFND--------------------------------------- --------------------------------KFKN----------------KVLKELAY RAGCQHQ------------PRKYE------------------------------------ ------------------R--YMEELKRLDEKS--------------------------- -----------------------VAWFSKL------------------------------ -----------D-----------------------TQKWTQAYDL--------------- -----------------------GYRYGWMTTNIAECINGVLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MUDRAVI2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LSIDGTHL---YGKYKGT -----LMIA---MGC-----------------------------------------DGNN -----------------------QLFPLAFALTEGENIDSWG------------------ --------WFL-TCIR--TRVT-------------------------------------- ---------------------------HRR--------------GLCVISDRHPGIMAAM SDVHLGWSEP-------------------------------------------------- ------------------------------------------------------------ ----YAYHRVCMRHLASNFMT--------------------------------------- --------------------------------RFKD----------------KILKNLMC RAALATK------------IEKFN------------------------------------ ------------------K--HMNTIGRINAAA--------------------------- -----------------------QQWLEAI------------------------------ -----------P-----------------------FEKWALSHDG--------------- -----------------------GRRYGIMTTNMSEVFNSVLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MDR2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LAIDGTFL---TGKYQGT -----LLTA---IGV-----------------------------------------DAGL -----------------------HLVPLAFALVEKENTSNWE------------------ --------WFI-NMLR--NKLI-------------------------------------- ---------------------------GPN--R-----------EVCIISDRHPGILNSI IHIMPHHL---------------------------------------------------- ------------------------------------------------------------ ----TIHHRWCMRHFCANFYT--------------------------------------- --------------------------------AGAT----------------TDQMKDLE RICQINE------------KALFL------------------------------------ ------------------D--EIKRLMGVVGER----------P---------------- -----------------------KKWLEDH------------------------------ ---------MPL-----------------------KVKWARAFDT--------------- ----------------------NGRRHSIMTSNMAESFNNVLR----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR2_OS ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LCIDGTFL---TGKYRGQ -----ILTA---IGV-----------------------------------------DGNN -----------------------QVLPLAFAFVESENTDSWY------------------ --------WFL-HLVK--TEVV-------------------------------------- ---------------------------GMR--P-----------NVCLIHDRHAGMLRAI EELKFGSMERGYPGQWE------------------------------------------- ------------------------------------------------------------ ----DVQSRWCMRHMGANFFK--------------------------------------- --------------------------------QFKN----------------KELMNMFK RLCNQNQ------------EKKFN------------------------------------ ------------------E--LWKRLDELTGKC----------SDQRATRPAAAVPDPPQ ALGALPTDSVTLVRRTGEQIRKFSQWIENE------------------------------ -----------P-----------------------KEKWAKTYDT--------------- ----------------------GGARYGIMTTNLAEVYNWVMR----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-3_SBi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LSIDGTFL---LGKYMGT -----LLVA---ISC-----------------------------------------DADN -----------------------ALVPLAFALVERENKDSWG------------------ --------WFM-RLVR--IHVI-------------------------------------- ---------------------------GPH--R-----------EVGVISDRHQGILSAV QEQIPGYA---------------------------------------------------- ------------------------------------------------------------ ----PLHHRWCTRHLAENLLR--------------------------------------- --------------------------------KDGT----------------KDNFPLFE EVARMLE------------VPFFE------------------------------------ ------------------E--KLEQLKTATNAE----------G---------------- -----------------------RQWLLGL------------------------------ ---------MRE-----------------------PEKWTRAHDN--------------- ----------------------GGWRYEFQTSNMAESFNSVLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-9_SBi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VLVDGTFL---TGKYRGT -----LMMA---AAV-----------------------------------------DPEN -----------------------QIVPLAFALAEGENNDSWS------------------ --------WFM-RLLR--LHVL-------------------------------------- ---------------------------GPS--R-----------TICLISDRHIGILNAA GEHIDGHP---------------------------------------------------- ------------------------------------------------------------ ----PLVHRWCMRHFAANFWR--------------------------------------- --------------------------------RQRK----------------KEVADKLK ELCNKRT------------EHEFK------------------------------------ ------------------E--TMAELQKMMNRA----------G---------------- -----------------------KAWLDQQ------------------------------ ---------MEN-----------------------KAKWALAYDE--------------- ----------------------GGFRYGIMTTNSSESFNRVFK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >VANDAL14 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IVIDGAHL---KGKYGGC -----LLTA---SGQ-----------------------------------------DANF -----------------------QVFPIAFGVVDSENDDAWE------------------ --------WFF-RVLS--TAIP-------------------------------------- ---------------------------DGD--------------NLTFVSDRHSSIYTGL RRVYP------------------------------------------------------- ------------------------------------------------------------ ----KAKHGACIVHLQRNIAT--------------------------------------- --------------------------------SYKK----------------KHLLFHVS RAARAFR------------ICEFH------------------------------------ ------------------T--YFNEVIRLDPAC--------------------------- -----------------------ARYLESV------------------------------ -----------G-----------------------FCHWTRAYFL--------------- -----------------------GERYNVMTSNVAESLNAVLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >CUMULE ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IVMDGTFL---KNKYRGQ -----LIVA---VCL-----------------------------------------DGNN -----------------------QIYPLAFGVVDRETDDSIQ------------------ --------WFL-EKLK--GAIG-------------------------------------- ---------------------------EVP--------------NLGFVTDRKTCFAKGI SSVFP------------------------------------------------------- ------------------------------------------------------------ ----SAFHGLCVQHLSQNLHD--------------------------------------- --------------------------------KYKN----------------DTVATLFY NASRTYR------------ESTFV------------------------------------ ------------------E--AWRHLLSFPNGS--------------------------- -----------------------GKYLNDV------------------------------ -----------G-----------------------IARWSRVHCP--------------- -----------------------GRRYNMMTTNIAESMNSILK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MULE-2_Cglob ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IVADCTYK---TNRFGLP -----LLNF---CGI-----------------------------------------QALR -----------------------KSFSIAAVFINAEKEEQYT------------------ --------WAL-QALR--EFLT-------------------------------------- ---------------------------EEDLPL-----------PKLIVTDRELALINAL KRHEAFT----------------------------------------------------- ------------------------------------------------------------ ----LVPRLLCRWHVNMNVLA--------KGK---------------------------- -------------------------------RFFPPATRLPD----------GSIKRNER FTAYLKDWNA---ILTSDTEELFE------------------------------------ ------------------S--RIQSFKSGRYPI----------GAVNYAV---------- -----------------------KTWLDPYK----------------------------- ---------ELL-----------------------VDAWVNKILH--------------- --------------------------FGNRTTSIVESLHAGMK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MULE-1_Cglob ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LGLDNTYK---TNRFHMY -----LFEV---IGI-----------------------------------------TDQK -----------------------SVANFAFGLINTEKEDGFL------------------ --------WLC-QQLE--DLRQ-------------------------------------- ---------------------------DLHVPA-----------PTVVITDKETALKNAL TATFP------------------------------------------------------- ------------------------------------------------------------ ----GAQQQLCVYHINAKVRA--------RIR---------------------------- -------------------------------SRWKAEDGRSD----------DEVDEAGD NEAEVADGDGDLVARAAEQEVAEH------------------------------------ ------------------GCAALLPAADPLTRD----------GMFRAWQQVVYAEDE-- --ADFQSAWNKMKAIYNPTQNHILRYISKEY----------------------------- ---------MPY-----------------------REQWARCFIK--------------- ----------------------RYRNFGQRVNSPVETAHKDVK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Hop ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LILDSTYK---TNRFKMP -----LLDI---VGV-----------------------------------------DACQ -----------------------RTFCIAFAFLSGEEEGDFT------------------ --------WAL-QALR--SVYE-------------------------------------- ---------------------------DHNIGL-----------PSVILTDRCLACMNAV SSCFP------------------------------------------------------- ------------------------------------------------------------ ----GSALFLCLWHINKAVQS-----YCRPAF---------------------------- -------------------------------TRGKDNPQGLGGESEEW----KEFFNFWH EIVASTT------------EDIYN------------------------------------ ------------------E--RLEKFKKRYI----------------------------- -----------------------PDYINEVGYILETWL---------------------- ---------DLY-----------------------KKSFVKAWVN--------------- ----------------------THLHFEQYATSRVEGIHSLIK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-4_SBi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VVFDSTYR---MNRYKMP -----FVPF---VGL-----------------------------------------NHHR -----------------------NTTVFGCGIICDERADSYI------------------ --------WVL-QAFL--KAMC-------------------------------------- ---------------------------QKK--------------PQSVITDGDYSMIKAI RQVLP------------------------------------------------------- ------------------------------------------------------------ ----GVSHRICSWHVEKNILK--------------------------------------- --------------------------------HLHS----------------NCLDGFRT LLYYAS-------------SETFE------------------------------------ ------------------A--RWNAFLSEYETA----------TN--------------- -----------------------REWLAMM------------------------------ ---------YKN-----------------------RKLWAAAFQR--------------- ----------------------DKFFLGMRSNQRSESLNSSLH----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-8_ZM ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VTFDTTHK---TNMYDKP -----LGMF---VGS-----------------------------------------NHHL -----------------------QCTIFGFALLGDETVDTFE------------------ --------WVF-NTFK--TCMG-------------------------------------- ---------------------------CDG--------------PRVMLTDQDPAMPIAL GRVFP------------------------------------------------------- ------------------------------------------------------------ ----NTIHRLCLWHVQNRYMP--------------------------------------- --------------------------------HLNELYARFEDM--------DFKTRFQS IIHHPLN------------EMEFE------------------------------------ ------------------A--AWQMMLDDFQLH----------E---------------- -----------------------NNTLARL------------------------------ ---------YEI-----------------------RKDWVPAFFK--------------- ----------------------GDYCGLMVSTQRSESMNKLVK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-6_SBi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IFFDTTFC---TNRYNMP -----FAPI---VGI-----------------------------------------NNHA -----------------------QSILLGCALLPDETTETFV------------------ --------WVL-QTLK--DAMG-------------------------------------- ---------------------------GIA--------------PTNIMTDQDRAMKAAI AQVFP------------------------------------------------------- ------------------------------------------------------------ ----STTHRCCKFHVVSKACE--------------------------------------- --------------------------------KFGWLIRNNP----------EFADEFDY CINFTES------------PEEFE------------------------------------ ------------------T--LWHNIGVKYDMH----------S---------------- -----------------------NDHFQNM------------------------------ ---------SST-----------------------KSMWAPAYFK--------------- ----------------------KCFFPFTSTTGRSESMNALFK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-5_OS ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VSFDTTYK---TNRYDLP -----FAPF---VGI-----------------------------------------TSHG -----------------------DNCLFGYAFLQDETSETFQ------------------ --------WLF-NTFL--DCMG-------------------------------------- ---------------------------GKV--------------PATIITDQDLAMKAAI AIVFP------------------------------------------------------- ------------------------------------------------------------ ----DTVHRNCLFHMLSNARD--------------------------------------- --------------------------------KTGRTFNSEDE---------EVYKDFHD IVTKSQT------------EAEFE------------------------------------ ------------------Y--LWKDFIRRNNLY----------N---------------- -----------------------VRYFQLM------------------------------ ---------WVT-----------------------RKRWAPVYFK--------------- ----------------------SNWCPLIQTTARSEGTNSRYK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Jittery ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VSVDATYS---TNQYNMR -----FAPF---TGV-----------------------------------------NHHM -----------------------QRVFFGAAFLANEKIESYE------------------ --------WLF-RTFL--VAMG-------------------------------------- ---------------------------GKA--------------PRLIITDEDASIKSAI RTTLP------------------------------------------------------- ------------------------------------------------------------ ----DTIHRLCMWHIMEKVSE--------------------------------------- --------------------------------KVGHPTSHDK----------EFWDALNT CVWGSET------------PEEFE------------------------------------ ------------------M--RWNALMDAYGLE----------S---------------- -----------------------NEWLANR------------------------------ ---------YKI-----------------------RESWIPAFFM--------------- --------------------D-TPLAGVLRTTSRSESANSFFN----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MUMET1 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VSLDTTYC---TNYANRP -----LAFF---SGF-----------------------------------------NHYR -----------------------GSVIFGAALMYDETSESFR------------------ --------WLF-DTFL--QAHN-------------------------------------- ---------------------------NKK--------------PKTIFTDQDQAMARAV ADVMP------------------------------------------------------- ------------------------------------------------------------ ----ETHHGLCTWHLLQNGVK--------------------------------------- --------------------------------HLGNMMKGGS----------SLLSDIKK CMYDIDI------------EANFE------------------------------------ ------------------K--LWFDMIHKFNIH----------D---------------- -----------------------KSWIIST------------------------------ ---------YEL-----------------------KKKWASCYMK--------------- ----------------------GVLTLGMRSTQVSESLNAHFK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MUJITOS2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VSFDTTFD---TNKCEMP -----FAPL---LGT-----------------------------------------NHHK -----------------------QTIIFGAALLFNQTIESFV------------------ --------WLF-ETFL--TAMS-------------------------------------- ---------------------------GKH--------------PSTIFTDQDAAMAAAI AFVFR------------------------------------------------------- ------------------------------------------------------------ ----NTSHRLCLWHIYLNGGK--------------------------------------- --------------------------------NLSHVIHKHPN---------KFLADFKR CVYEDRS------------EYYFN------------------------------------ ------------------K--MWHELLSEYNLE----------D---------------- -----------------------NKWISNL------------------------------ ---------YKL-----------------------REKWA-IVFR--------------- ----------------------NSFTADITSTQRSEGMNNVYK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MULE-1_CapOwc ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LFLDSTFS---VNRYDWA -----TTAL---VAA-----------------------------------------DESG -----------------------AGVVPLAFMISDRDREHEY------------------ --------ARF-LSEV--KHAV-------------------------------------- ---------------------------GEA-FN-----------PVRIVIDKCGAERNCI NQAVP------------------------------------------------------- ------------------------------------------------------------ ----GVQVATCWFHVCQAVER--------------------------------------- --------------------------------------------QYPGRLDLLSCMAKMR YARNAQEL-----------KDASN------------------------------------ ---------------------SLLNAAGEFQGY----------FL--------------- -----------------------SQWLN-------------------------------- ---------ERD-----------------------IKTWT-LFHL--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus-3_TC ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LYFDATGS---VVRNQSD PKSTVYYYA-G-VVV-----------------------------------------TKNH -----------------------RVCPVLEMVSSEHATNNIQ------------------ --------DLF-VRFINFCKES-------------------------------------- ---------------------------SMSNIP-----------FETVVTDFSFANIHAV CLSFNEMTLNQYLSTCFDLAIHHK------------------------------------ -------------------------------------------------------SV--P --KKIKIIRLCAAHFMKNICTHLNEFVGQSKK---------------------------- -------------------------------SHHKSFIKELIACAFNLT----TFEDVKF WFENACIILM---------YETYN------------------------------------ ------------------D--AVQIALHNISSI----------ANSLSTNLTKNIGDDDF GIDHSVSVSEDFISHTKLRKNS-PFYKEFL------KIFNAVVAKEEKHNNSNIYCCKEF MNYILDRYIPFL------------------------PMWT-LIIH--------------- -----------------------TKHSERVTNNAIERYFGILK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus-1_HR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IHLDSTGS---VVRRLHS KQTIYLYSA-V-VGL-----------------------------------------D--A -----------------------GYAQIFDFISDRHDTASVA------------------ --------YHL-INFKRYVIKK-------------------------------------- ---------------------------VNAWPI-----------FMNVVTDHSMAMINAV LTGWIGVDLRGYLAMAFKWCISEC------------------------------------ -------------------------------------------------------V---P --KNQIMIKLCCAHFFKNIVRFVKKNFSTKEV---------------------------- -------------------------------VKFYINAFSVILQAKSYRRMINLITSFFH ITCSLKKTPSLNSHFDEFHESTIN------------------------------------ ------------------EVSHYDLIEHVYDDD----------DNEVNELETIYESSPFY RKGLQIL----------------EHVNDQL------------RLVNDEQTEPNEYCNKTF AKLVLKKYISIL------------------------PLWT-VLL---------------- -----------------------NKNGERTSNSKVENCFRFIK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus-1_TC ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LHLDATGSV--VHSPPET KKRVYYYAG-V-VHI-----------------------------------------KDKE -----------------------LVCPVFEMITSEHDGYSIG------------------ --------SWLQAFESFIVKSK-------------------------------------- ---------------------------QLKWSI-----------FSYVVTDFSFAFINAI TTQWNKMDDISVYLNIVYDYITSE------------------------------------ -------------------------------------------------------TTVRP ----KITLKLCCAHFMKLITN--DINK-ICGS---------------------------- -------------------------------NKTQKKFFKHSIAAVFMKTSLPEVEKWFK KMVLITSKEFLDLDGKL--SNVIS------------------------------------ ------------------K--MFDTLNNSKDLE----------DIDEETETETEDTEIPH TLYQKSKFY--------------RHFFKIC------EQDKKMINSAIDSDNINIFYNPLI LDLILKKYLPIL------------------------PLWSNIYPN--------------- --------------------LRDRDSIGRFSNAPVENWFCQVK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus-2_NVi ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LSLDATGSVA-LKIKRPD GESADIFLT-V-LST-----------------------------------------YIKS -----------------------MIVPVAQVLSEKNDTNFLS------------------ --------YWL-LEWR--KSGA-------------------------------------- ---------------------------KIP---------------EFIVTDMGKGIQNSV CLSFNTMNFSKYNDECLKILLNAQ------------------------------------ -------------------------------------------------------YKIEL ----NTQLRTDVAHLVHAVTKWPCFSSDKPKV---------------------------- -------------------------------KELFKRCVGFMTGIDNLKNFSEFLVAVFI VSNSKNN------------DDNCQ------------------------------------ ------------------K--ALKYLIERIQTY----------KFNANVTEKLELLDQKE TLDIFADIEEFNTKSNQRLT---RKYVDELKVKPIKNKSDNKSDNSSDFNIQNNDYYLPN FAERLSILCAEF------------------------PCWTKVMNV--------------- --------------------Y-FDNSEDVATSARAESYFSDYK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus-1_DY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ISVDATGSVV-LPIQKPN GDSSYVFLY-Q-IVM-----------------------------------------EGDD -----------------------SIFPVFQMLSAKHDTASIQ------------------ --------FWL-SRFI--SKSG-------------------------------------- ---------------------------HFP---------------LEVVSDFSLALLNGI SLSFNECRIKTYIQKCFQSLLTDE------------------------------------ -------------------------------------------------------RTDLP ----PCFIRLDIAHLIKMICRKNVFKGKLPNI---------------------------- -------------------------------KDFYVRCIGLATTCETKDCFAETIKSVLI VALSQSSGEDEKGHFLSSYRNERN------------------------------------ ------------------LLTRIATFAAQDHDE----------KHEENFIPEDQEEVDED V----------------------SEFVLNI-----KNAAEEEALKCNSVRCRPNPYFLPD LMSPLLKLCKYF------------------------VLWTNVMKE--------------- --------------------K-FCSKYDVGSSALVEAYFKDLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >Rehavkus1_AP ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------IIIDATGSLIKNFKKFGM NKTKTIYLYEALVYD-----------------------------------------ESKL -----------------------HSFTVSNMISERHTTLAIY------------------ --------NWL-ANWL--NFNV-------------------------------------- ---------------------------PSP---------------RETVCDQSMALLSAC VKCFTQYSSLKQYIRVCAKLALGK------------------------------------ -------------------------------------------------------LSPDP IWLLNCFIRTDVAHFIKLVSKWVPLKNTQGRV---------------------------- -------------------------------KEVILRSIGVIIKNQSISEIYSIVLSLFV VLTNESDGINAETGRDTPCEYHKK------------------------------------ ------------------KIIITSTGFVNYEEW----------YNE--VFSTVDSEEEIR DFIEEDETKNIDLDND------KNSF-QSW-----AEEIFEKSKEYIEEGNGINVMYLPK -LVPLIIKCMHF-----------------------LPLWSGFMIP--------------- --------------------I-FKYGKLTASSAGVESSFKKLK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDR-2_DR_prot-Repb ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MEEIIREAVYKEEHFKGNRKETNITVH VLEKDLDPCEFIQQRLTTINASKDANFRTVNSASLQNQRNGYFLFSCKRSGACTQRSRRA KGCKAYVSFKKRTDWLNKLVIVERLYNIHSGHDPLSSF------------------EGHS ENISQELVKHIQDLIS-------LGVKPDTILLKSHEWSKEQGHTDLNNRA--------- --------YFVTPKDIENIRTCMMRKHQQHKDDATSTSRLLEG------------PFKNL VVFYQPYSPQTDLVIVLQTPSMKENLQEYGRDIIFMDATYGVNQYGFPLFTLVVRDSHGH GIPVAYIILGNEKQDTLQLALEKL---------------------KPTFSVPPRFVNFAT FLFSYKHGLFVWSVLVTANSIVILVYLIIDPQCFRQYKNITDS------------LSVDL LHTLGYVCVKDYLKYLKISSSSYANMKDDF-----------PCQFLQAQEFKEKAEMFH- -------------------------------CQFRNFKNVCKYFKNHWETIGHLWSNFGR CYKHGDSDTNNLIERYISFVSMFISFTCLSVHCSSHCTLFLHVFLLYSFFHRLKYQFLCG IRNRRLDHLIDVLLNK--TDNYFNTIQD-LQSVGRVNNPLQCKTEEIKKSAERMLENG-- -------------------------WAMKITIA-------STETYMYNVPSENNSHAVYT VCPAEQFCSCVS---GSRVHVCKHLFLLSLLSCGDHVTFPDMDTQLQAHTNNLMLTNKYS ISAKPEKTIAVESLFGRAASKPCIVRGICDCCTFSYHKKCSCLLLAKKLFNEVTETKSNN ATNNSIVPIQNDIEKKSADEDRLCTIRKLENVLRIIQTWDNIPEDIAQKVNDLEVQTKEQ TMNNEF------------------------------------------------------ -VRQCDADKSRKIHPLFANRKRKTDGHTHSETKPDISFPVKPRRKRKENKRFFF--- >MuDR-3_DR_prot-Repb ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------RILLFY---------- ----------------------------------------------CIRSGAPLDGSRKS SGCKAYTSFKVKNDWLTHKVIVQRTNNGHNAT----GK------------------EGHF QTVCPELVKQIEEWIS-------LGVRPDVILLEAHKWSRSRGHTDFNNRQ--------- --------YFVTPKDIESIRTC-------------------------------------- -----------------------------------------------LVRRNHLDKDYAV SSAK-----------LLNNHCKDS------------------------------------ -------------------------VVFFQP----------------------------F SHEKDLIIILQTPNMRENLQRH-------------------------------------- -------------------------------GKNIIFLDA-------------------- --THCVNQYNF------------------------------------------------- ------------------PLYTLAVRDD---------------YGHGVPVAFIITNNE-- -------------------------KEATLELA---------LHQLRRAGFTALRY--V- ------FLAVFF--------------------FFFLLFYIFNQHE----FKST------- --------------------AEEFLKRFEDFLALCSFIRDHWL-----EIGHTWSDFGRC YNHADSNT---------------------------------------------------- ------------------------------------------------------------ -NNRVRMLNFK---------------------------------------------- >NOF-FB_protein_Repb ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----MPAKPQVDGHTLVDAFCCANIFTETGALKPRSDKVWMDISNQLKGAISAKTLNFY ARINRNNMITVVKERCGIQQLDTSANLTLNSTFPDDDPEFQITEASKNGPLPILYFNLEL DLELWRSIAPKKDQKTEKLQPNWTDTMAKLIYKKVPLPCAFNFRKAKLSDKVDNIWLRIE GYCND---------------------------------------CSSILKGHCLVKPDEQ CGIMISVSVPDTRGI-----PHNKKRRCTGSRRLEIGNELILKKAALWRKEATDNMNDDD PEPSYIPNLPTLRKLREEATNRHLGITKDRDPVSSLYLKKYE--------GELAGCILDI GLDEFFCIYCTGTQVKTYASRIKTIRKISIDATGSVVLPIQKPNGDSSYVFLYQIVMEGD DSIFPVFQMLSAKHDTASIQFWLSRFISKSGHF-----------PLEVVSDFSLALLNGI SLSFNECRIATYIKKCFHSLLMEERTDLPPCYIRLDIAHLIKMICRKNVFKSKLPNLKDF YTRCIGLATTCETKDSFAELIKSVLIVALSQSSGEDEKGDILSSYRNEKYLLARIATFTA PDHKETIEDNCIPEDQEEIDEDVTDFISNIKIAAEEEALNCNSVNCRPNPYFLPELMPPL IKLCKYFVLWTNVMKEKFCSKYDVGSSALVEAYFKDLKNTDMSIFHRPVRADKFVVQHIR CIEAVCKLERAAMKRKTVKTPSFIKENAPKKMCSKETKGFLEEILEESEVEYLLQE---- -------ENWKVKNKTI-KPTEGNDAED-NDTDDENKEMDLSEQPKEKPRGKYLKKCPNV ELLYNRPHRRKQDEILHNGGSMGPVWIGKQLLQFKNTCPFDSLVEILSTAYIDNFY--YK SLLDDFYTDNLTIELVKKYAVEGVSSSLYCDRGLVLKSFFDEKHQIIKCDANI------- --------------------GS-FIEKALNGVP-SASSHRTHIKNNHDCRNQKYIHHRLE VIDVEKVGHLDVQEVVIPFIDEFFARTDGECKICGGQQILERQPGPHVILDIEFAMDAFH QIHHNGLPGTTTLLQVPEEILIQEKKYILSGA---------------------------- -IEYVPAMGGEIGHYIAYCRRVIGSWEVHNDMCRQWKKFSALNTKMTLHILIYTRKN >MuDR-1_DR_prot_Repb ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----M---------------------------------------W-------PVQFHNGK KSLINFVS---AL----------------------------------------------- --------------------------PCKSGILDQYAISRYQ--------H--------- --------PGSLP----QGKKC-----------------AVSL---------------YL D---------------------------ATGGV-----------VSKILEQSKRVLYYAL TLPG-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------EGRDAPPLP VCEMLSNEHS-------------------------------------------------- ------------------IPPXAFWLMQ-FQLK----------LSKYTRVRVQKVETD-- -------------------------YIWALM---------QVVVLAFNRHNIDAYL--E- ------WTYAVC------------KK---------IKTWVXIKQI--------------- --------------------------TVSASLF-CPHYQGLFQ-----MFNVFYDLKKG- ------------------------------------------------------------ ------------------------------------------------------------ -LAAERQLDDRERD------------------------------------------- >tr-F4R5C2-F4R5C2_MELLP_Melampsora-larici-populina_98AG31 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MLSSD---------------------------------------CS------SIAGPSPS TSW---------LMY------SRTYSK---------SE------------------QAIV NESNEKI------------------RKDNSKSKGGAKLTDHH--------N--------- --------HSHAK-DSSSSDKF-----------------LLE------------------ ----------------------------NGGKR-----------KKKAIDHVEDDSSEEG KSAKRVKLV--------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------D-DMKP- -------------------------------AYSQLVADA-------TASATAKVKQQVK SIKTCKTQES-------------------------------------------------- -------------------------------NT----------VDEAQCGDSKRSHKG-- -------------------------W---------------------------------- -------------------------------------VWVEERPE----SN--------- ---------------------D-LLPKDNQHVQ-SQVETSS------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----RRTRSGRAIG------------------------------------------- >tr-F4R8A1-F4R8A1_MELLP_Melampsora-larici-populina_98AG31 MSESGEDWTDDELFHSDDESDSDTSQIMYQQDIGLHLLEAETSPPQKAEILTAQTNKSRS KSRTEKVGKKGKKTFGLPLDRPSFQTFIDHGTTLDRQGYPLFPNGSTVFVKQPKQECANW LTVGFVSTTSGGGTSKRPDWRTVRFTCLGVVVCNNPDCDNLGAPPTGKGKIDAWLSKPRK CDAALCNDYLRLIKCKDTICRVDEHIPSGWGVLRHSGVHDHPWPRRRKPDKLALEDFAQK VIENPNMGPLQHKVGRAPAGKGEITTARNYHPSLANLHRLGYYRRWILVNNGIIPEKKIP GSGDNFILDMETWADV----------------------------------------YTGG LLSDVTYKFFANGYLLSTSMYSDVLQRWIPIQLTWLRGLSQKHYLAHFKTLMKQIKDSDL SVEERDTLVRNVVDFSLAQKNGFISAYMSVFNETDHNVALSKLRGCKEHFRQQITRLKRN NAIIPRGKEGDFEDLAMSLCDRDVPGGKTYDEKVDTLRRDFPQTKRWIDWWQASNIQAML FKSRRKQIDDDGLDDDMPETTNAQESIHRVYYMISEGNCTVQVGLVQLYA-------LVM SLQKD---------------------------------------HVDLCRGVTIAYGS-T KNYEKVAQ---ILGW------AKKTRKNREP-----KN------------------DGQP PDTTEALLGVVSKKKK-------VGRPKGLLNVDRNPVTTFQ--------G--------- --------FRSST-VTGRRNRC-----------------WMNS---------------MS ECLYALSTPF-----------WFTGSKGKSLHV-----------YNVLMNLFSTRATWEV HQSGNIRTILKQKANVIADEDEDH------------------------------------ ------------------------------------------------------------ --------------KEEQPVKS-------------------------PSKKDDD------ ---------------------------------------------------EGQLTGKGQ EVKPPERRVRA------------------------------------------------- ------------------KPYKRKLNDN---------------KDEEPPPTNMQSKKL-- ----------------------------RVNLH--------------------------- ------PAANVA----------------------------ETAAD----THEV------- --------------------AE-TKPTSSPSKGQGPKKLKGWK-----GYALIDVEDDDK EE---------------------------------------------------------- ------------------------------------------------------------ -VKGSSQENGHGNGKLRKSKLPMFAV------------------------------- >tr-F4RIM3-F4RIM3_MELLP_Melampsora-larici-populina_98AG31 -MSSYSDFEEQEDDTYQPYQDGYEDKVADSEEEQDLPLPKAASQNSKSTTQSNGSSTINL SNKSNKPGKKGKKTFSLPQDRASFTTFIDDDTTVDDKGYPLLPNGNTVFVRQPDQKLVNW GTFQFTYTTSGGGTGKGSDWRTIRFTCLGVFICNDLDCRYRGSPPTSTNKRLEWISEHRK CPAARCPGVLQYLSCKNTICRLDEHIPSGWGIIRHSGIHNHPWPRRPKPDKLSLGKLGKK VVDNPDVGPLRLKVGRAPAGKQEIVTATSIHPAFGNLHRTGYYRRKLLVAAGVIPEKKIP GAGDSFILDMIHWSKRGLRMISCSFMPKDTHMTFQTNWMAGQLLSRDEDDSIYRGGLLSD VTYKFFANGYLLTTSMYNNVLNRWIPIQLTWLNGLTEEHYAAHFTTLMRQMEDARLASHI TNEERDILVRQVVDFSVAQKNGFVMAYMDVFQEHDRQVALSKLKACHEHFRAQVTRVKRN RVIIPAD---------------------------DELRKEWPKAKKWIEWWQAADIQSML FRSRPRQIDDDGLCDDLPATTNAQESMHRVYYMISEGNCTVQIGLVQLYA-------LVG SLERD---------------------------------------YDDLCKGVPIEYGGEA KNYKKVAQ---LLGW------SKKMRKPRDV-----KN------------------DGRP PDTTDELLGRPKK----------LGRPKGAVNVDRHPVTTYQ--------G--------- --------FVAST-TPGRQFRC-----------------WLDA---------------MT ESLYAVHTPL-----------WYHS---PSSPA-----------MT-------------- ------------------------------------------------------------ -------------------------------------------Q-----------TLFRV NIKNKLVCSNHKSHILNESNHR-------------------NSITLSHERFGGQ--FSY- -------------------------------SDIPALLQQ-------WTSPSGLQRVSAR HCCTCRGQKDEGQSNPPY-----------------------------------LER---- -------SQLHLDP----PPPHLHINLD-IAYL----------LGT-----RLFDEGS-- -------------------------W------------------------IWGSGH--Y- ------WCKVVQ------------TV------GALTGVWLNNDLV----NAGV------- --------------------AT-LVSSNLKSIG-GTAPNTTWA-----MYSREPTAEESK VIKKSKAIIYKAIGHKVKGEGSSGEKEKYIGAVAPGTENTNTSTQLEECFDFALDGEAGK GKDEKDYSQQLEECFGTEEEAHDPKDYSQQLEECFGILDEEEARETGSLFDDIMSPKELE DMIAFGMDKSDTDGEEDIPLVTLSPKKDKDGGRSRPRAVGVSRRRRSDSRRSDST-- >MuDRF-2_MLP_Melampsora-larici-populina_98AG31.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------FIQLLA-------FVQ SLERD---------------------------------------YQNAQKGVSIAYGSSQ KNWEELVK---GLGM------PKPTKRRYF------KN------------------DGRP PDTTDELLGNTKKTKASTRT---PGRPRGSQNVNRAALTTYQ--------S--------- --------YTKGT-RPGTTNRC-----------------WQSS---------------TL ESLYALFGPL-----------WSDFGSVNGSGL-----------VHVLYQHLTKRCTAQL QG-KNLGRLLSSHQNLLHNTLRT-----------------------PTSYQPDKMASADQ FM-----------------------ERLLRPG-RHSL------R-----------PLFEV PFIKAHIC--------PADAKHTRVESKTR-----------ACQALFPYNFTDA-GLSY- -------------------------------DEVGLMIDL-------LMS-EGLSTDSRL VCRKCHPEDN------NEDESDCVIQASPPQNLTT-----------------LVEN---- -------VKIDLTSNPKLAPLHLYFLLEGIAGL------------EASARVDFQNNTN-- -------------------------WPSRIIVG-------DVEYCLMTRGYWGGLH--Y- ------WCKVVR------------DV------EGILGVWHYDELQ----SGGF------- --------------------AQ-LLSRNITSIG-GCDAQTSWL-----CYSQ-------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDRF-3_MLP_Melampsora-larici-populina_98AG31.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MIQLFA-------FVS SLERD---------------------------------------YEARCKGISVTYGSSN QNWQDIVT---SLGM------AKPTKRRYV------AN------------------DGRA PDTTKELLDGADXKSGKPSKKKGPGRPRGSLNINRSALTTYK--------S--------- --------YTSGT-TIGXLNRC-----------------WQTA---------------TL ESLYALWGPL-----------WSDHTHVNGTSL-----------PTIIIRHFTGRCDGEL NEGKHLGSLLKRXQNIIHKAIQAL---------------------KPESYTSDKFCSADG FM-----------------------DMIVD-H-PHT-------R-----------PLFAI NVTKTLICHR--------NDKHNRATTRSL-----------GGFRLFPSMFRES-GVAY- -------------------------------XQLDILLQD-------LFS-EGVLTEPXL VCRGCHPIKEKGHEEEDPT----------------------------------LYD---- -------QRMKIEDTS--LXLHLYFLMD-NVMA----------LDS-KERGRYMGDTN-- -------------------------WPARLXXG-------EAKYQMVTRGFWGXNH--Y- ------WCQVVX------------SV------EGVLGVWHYDELK----NGGF------- --------------------SQ-LISRDVDSLS-GCIANTSWT-----CYTR-------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------- >MuDRF-1_Mlarici_Tpase ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MVQLYA-------LVK TLERD---------------------------------------HEDVMRGITVEYGSLS RHYKTVAE---SLGW------TRKHRKQRAV-----PN------------------DGRP PDTTEALGLKSKK----------LGRPKGSRNVDRNPITTYQ--------G--------- --------YIASS-ITGRQFRC-----------------WEDS---------------ML ECLYAIHNPL-----------WYRGSRGKSGDI-----------FTKMMRHFSARTSFDM NHLGDIVSILSKGQDNLHEAIEDA---------------------YRGSFKPDTFSSAEL FL-----------------------EGLFDPR-KNSSKAV---Q-----------TIFQV QRECRYTCSRKCAEDHESDDRNNKIKIRKL-----------IGLNLRPEDFEAA-DLEY- -------------------------------GQGPELVQK-------LCS-VGVYSQSNY HCKPCMDDDKKAKLILEKKKSTLKTATAIPKAIPP------------------FCY---- -------QLVQYNLTS--PPLHLYIHQD-ITPL----------LSQNLPYDSFMCDSN-- -------------------------WPATMKLG-------GNEYTLKARGYWGNKH--Y- ------WCKVVR------------TL------GGVSGVWLNDDTL----NKGI------- --------------------AR-MLSSDCSSIA-GPSPSTSWL-----MYSQTYSKSEQA IVNES------------------------------------------------------- ------------------------------------------------------------ -NEKIRKDNSKSKGGAKLTDHHNHSHAKDSSSCKCISANNQICRVFTESACCSLL-- >MuDRF-1_MLP_Melampsora-larici-populina_98AG31.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MVQLYA-------LVK TLERD---------------------------------------HEDVMRGITVEYGSLS RHYKTVAE---SLGW------TRKHRKQRAV-----PN------------------DGRP PDTTEALGLKSKK----------LGRPKGSRNVDRNPITTYQ--------G--------- --------YIASS-ITGRQFRC-----------------WEDS---------------ML ECLYAIHNPL-----------WYRGSRGKSGDI-----------FTKMMRHFSARTSFDM NHLGDIVSILSKGQDNLHEAIEDA---------------------YRGSFKPDTFSSAEL FL-----------------------EGLFDPR-KNSSKAV---Q-----------TIFQV QRECRYTCSRKCAEDHESDDRNNKIKIRKL-----------IGLNLRPEDFEAA-DLEY- -------------------------------GQGPELVQK-------LCS-VGVYSQSNY HCKPCMDDDKKAKLILEKKKSTLKTATAIPKAIPP------------------FCY---- -------QLVQYNLTS--PPLHLYIHQD-ITPL----------LSQNLPYDSFMCDSN-- -------------------------WPATMKLG-------GNEYTLKARGYWGNKH--Y- ------WCKVVR------------TL------GGVSGVWLNDDTL----NKGI------- --------------------AR-MLSSDCSSIA-GPSPSTSWL-----MYSQTYSKSEQA IVNES------------------------------------------------------- ------------------------------------------------------------ -NEKIRKDNSKSKGGAKLTDHHNHSHAKDSSSCKCISANNQICRVFTESACCSLL-- >MuDRF-1_PTrit_Puccinia-triticina_1-1_BBBD-Race1.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MVELFG-------FVS VLEEE---------------------------------------YNAVMCGVSVEYGSQT KMQVNISH---SMGW------AKPKKR---KF----IN------------------DGRP PDTTATLLDGPDPSTKKKN----LGRPKNSLNVDRSEYSTYQ--------S--------- --------YTASE-EPHLSNRC-----------------WMSA---------------AL ESLFALYNPL-----------WLQNSTGKGATL-----------FYHLTMHFGARTTFNL TKIGRIRTVLTNAQTKLFNMCNEK---------------------HQANFQPGAFASCDF FL-----------------------ELLLDPK-RNPTRAL---A-----------GLFEV VEHRQFVCGS----AEPCLIPQ----IRSL-----------TPIKIEMKNFLEN-GLEP- -------------------------------SDVLGLIKL-------WTS-TGISKTPGL VCXPCNQESTQNKPKPRGCPPKKPKDPSPEITISADEP--------NHTAEYVKET---- -------SRLAFKDDL--PPQHLYFFME-VTQP----------SNP-IERERYMGAMD-- -------------------------WPHQITIL-------GAKYTLLSRGFWNGYH--Y- ------WCKVLR------------TG-----RGTTTGVWLHDDRQ----NDGN------- --------------------AR-LVNTDASSIG-GSHAFTSWI-----FYSRVWTPDEES YVNSS------------------------------------------------------- ------------------------------------------------------------ -IAKIRSAHPNAEG------------------------------------------- >MuDRF-2_PGr_Puccinia-graminis-f-sp-tritici_CRL_75-36-700-3.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MAELFA-------FVK ALEDD---------------------------------------WHAVMRGVSIEYGSKN KTQHDLAI---SIGW------QKPPKRNPANRKKADQN------------------DGRA PDTTATLLPKNV-----------GGRPRNSPNLNKDPFSTYI--------S--------- --------YSASQ-DSAKKNRC-----------------WMAA---------------AL ESLYALFNPL-----------WLRGTNGLKADI-----------FTTLIKHFNSRTTWEL TQSGHIRTFLSIGQNSLQTAANKL---------------------SPGSFNPGVFCSCDL FI-----------------------DLLIDPTFRKQSKSMYPPR-----------ELFTV TEVRTATCQDRPSFDQPHPRG-----IRDI-----------TLLRIQKETFNAA-NIEP- -------------------------------SSIQAIISR-------WTT-DGIVTVSGL CCQACPSTQKTDKR------------------------------------HHLIEK---- -------SVLTIENE---PPQHLYLLVQ-VSTI----------IDQ-MAQQTFMAGLD-- -------------------------FPFKLDFH-------GVSYTLFSRGFWNGVH--Y- ------WAKMLK------------NV------GGISGVWMHDDRE----NGGI------- --------------------AR-LISSDHSTIA-GQARHTSWV-----FYSRAWIPSEEA FVVES------------------------------------------------------- ------------------------------------------------------------ -IARISRDNDGAQG------------------------------------------- >MuDRF-1_PGr_Puccinia-graminis-f-sp-tritici_CRL.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MVDLFS-------FVK MLEED---------------------------------------WKAAMKGIPISYGANP TT--DIGT---TLGI------AKKRKRGEGKF----IN------------------DGRP PDTTDELVDGKKKKKAK------LGRPPNSTNFNKSLWSAYP--------S--------- --------YHANKDNPTRRNRC-----------------WLAA---------------GL ESLYALFSPL-----------WLRGISGHGKDV-----------FTAIAHHFSCRSTGEL NGSNAIRSTLTRGQNMVFDVLSPK---------------------YPGRFLPGAFASCDY FL-----------------------EVALDPQ-LHKKDEY---K-----------QLFSI DEHRTFTCELQPNKLQKHPTRD----HRTL-----------HVLTIKPQMFDEN-RIPH- -------------------------------SDVSKLIEM-------WQT-DGLLATSGM ICKHCNPNKPKPKLPKNAKIQKVSSDVDIVKLLGS----------SENTSHHIIDR---- -------SRLAVPANG--APLHLNFYVD-VTGI----------TDE-KQKNNFMGSID-- -------------------------WPFKINVG-------GATYTLISRGYWQHNH--Y- ------WCKVLR------------SANISADKGSLTAIWLHNDAE----NDGY------- --------------------AQ-QINRVPSSIA-GVEENTSWL-----LYSRDWTPSEEE YVNNA------------------------------------------------------- ------------------------------------------------------------ -IQKIVAENPEAAG------------------------------------------- >MuDRF-1B_PSt_Puccinia-striiformis-f-sp-tritici.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MVDMFA-------FVT MLAED---------------------------------------WHAVMRGVSINYGA-- QKVKDIGL---TLGM------SQKRKRY--------AN------------------DGRP PDTTDALVEIGAQKPKHAK----LGRPRNSPNINKTPGSAFA--------S--------- --------YRAAPSDSDRANRC-----------------WMAA---------------AL EGLYALYTPL-----------WIRGINGKGNDL-----------FTYLTKHFSSRKTHEM TMAGSLGSILSKAQGKFFDMARQA---------------------YPGRFNPGVFASCDY FI-----------------------KILLDPK-QHPKNNHL--H-----------NLFGF AIRREFSCEAHPDIKQAPLAME-----RPH-----------HVLTISSDMFGEA-RLSY- -------------------------------GDVGKLLTL-------WET-DGLPLHSGR VCKSCLESKPLFKPPTPTKKKKQAKKPKITRVASEVEVLTDYINISGDNQHYLLEH---- -------SHLHFPDNL--PPLHLNIHLD-VTSI----------QDE-TRKRDFMDGTD-- -------------------------WPFKLTLG-------GYVYTLVACGFWNTYH--Y- ------WGKVLQ------------TS------AGMTGVWLHNDAD----NHGY------- --------------------AQ-LINRVPGSIA-GKAPHTSWL-----LYSRTWTPSETQ FMEES------------------------------------------------------- ------------------------------------------------------------ -IEKIQRDNPKPVG------------------------------------------- >MuDRF-1_PSt.pep ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------PPLHLXFHLD-VASI----------QDE-TRKRDFMGGTD-- -------------------------WPFKLTLG-------GXAYTLISRGFWNGFT--T- ------GARLLR------------TS------AGMTGVWLHDDAD----NHGY------- --------------------AR-LINRVPGAIA-GXAPHTSWL-----MYSRTWTPSEXQ FVEEA------------------------------------------------------- ------------------------------------------------------------ -IEKIRRDN------------------------------------------------