Table S10. FOXO3 expression and paitientsˇä survival time from TCGA KIRC dataset id futime fustat FOXO3 TCGA-T7-A92I 0.975342466 0 11.20529 TCGA-GK-A6C7 0.167123288 0 11.32872 TCGA-BP-4349 1.019178082 0 11.42553 TCGA-B0-4693 0.210958904 1 8.675994 TCGA-BP-5177 0.802739726 0 7.204416 TCGA-DV-A4VX 4.454794521 1 10.46656 TCGA-CJ-4893 2.054794521 0 6.959455 TCGA-BP-4174 5.147945205 0 7.888931 TCGA-CW-6087 0.112328767 1 8.737961 TCGA-BP-4166 0.035616438 0 9.6188 TCGA-MW-A4EC 1.364383562 0 4.94243 TCGA-CJ-6033 0.61369863 1 10.79504 TCGA-CZ-4860 0.564383562 1 8.542098 TCGA-CJ-5683 5.175342466 0 9.872188 TCGA-B0-5705 12.43013699 0 15.51694 TCGA-BP-4973 3.791780822 0 19.66711 TCGA-B0-5088 1.542465753 1 7.498622 TCGA-BP-5000 1.542465753 0 4.708723 TCGA-A3-3363 0.873972603 0 6.248601 TCGA-BP-4345 4.153424658 0 7.61753 TCGA-BP-5184 3.104109589 0 15.56236 TCGA-A3-A8OW 0.884931507 0 25.48295 TCGA-BP-4338 7.832876712 0 4.72024 TCGA-BP-4163 7.778082192 0 10.81535 TCGA-A3-3374 3.6 0 8.752373 TCGA-B0-5109 1.608219178 1 6.01307 TCGA-EU-5905 0.326027397 0 16.88222 TCGA-A3-3362 4.271232877 0 12.07577 TCGA-B4-5836 0.38630137 0 19.81149 TCGA-B8-4154 3.780821918 0 6.765347 TCGA-BP-4992 1.37260274 0 4.627371 TCGA-AS-3777 3.391780822 0 2.064891 TCGA-B0-4697 1.583561644 1 7.351147 TCGA-B0-5694 1.315068493 1 10.23557 TCGA-B0-4821 3.369863014 1 9.327038 TCGA-B0-5703 6.153424658 0 11.72462 TCGA-CZ-5988 1.898630137 0 14.80058 TCGA-BP-4351 2.657534247 0 26.47879 TCGA-BP-5180 6.2 0 6.309463 TCGA-CJ-4878 5.989041096 0 12.92807 TCGA-BP-5189 2.252054795 1 18.21306 TCGA-A3-3365 2.391780822 0 8.831945 TCGA-CZ-4853 2.120547945 0 13.00406 TCGA-CJ-4873 6.189041096 0 6.251484 TCGA-BP-4342 6.180821918 1 17.99293 TCGA-AK-3456 3.131506849 0 11.20962 TCGA-B0-4706 0.178082192 1 8.220207 TCGA-B0-4700 5.424657534 1 6.023659 TCGA-B0-5706 8.780821918 0 16.50514 TCGA-CW-6088 8.82739726 0 16.14423 TCGA-BP-4164 2.717808219 1 12.21503 TCGA-A3-3331 4.068493151 0 13.91268 TCGA-CJ-5677 2.142465753 1 8.591014 TCGA-AK-3450 4.873972603 0 16.6124 TCGA-CZ-5987 1.219178082 1 7.84519 TCGA-B8-A54I 0.410958904 0 5.478296 TCGA-CZ-5452 4.901369863 0 6.602829 TCGA-B0-5092 1.257534247 1 7.485918 TCGA-B0-4811 3.882191781 1 6.257475 TCGA-CZ-5982 6.682191781 0 8.304987 TCGA-A3-3373 4.44109589 0 13.67157 TCGA-CJ-6032 9.969863014 0 5.472049 TCGA-B0-4817 2.791780822 1 8.787325 TCGA-CZ-5457 7.545205479 0 11.77261 TCGA-AK-3427 9.816438356 0 1.444071 TCGA-BP-4177 4.575342466 0 15.35226 TCGA-CZ-5463 1.81369863 0 13.63962 TCGA-B8-A54K 1.284931507 0 14.76124 TCGA-B0-5099 1.328767123 1 10.86386 TCGA-BP-5199 3.712328767 0 8.75231 TCGA-A3-3326 3.115068493 0 19.67943 TCGA-CW-5583 6.819178082 0 20.80206 TCGA-B0-4696 2.37260274 1 4.501143 TCGA-B8-4153 2.087671233 0 9.161259 TCGA-B0-5698 9.947945205 0 10.55212 TCGA-CJ-4871 6.638356164 0 9.472149 TCGA-CJ-4875 9.736986301 1 6.200457 TCGA-CZ-5453 6.62739726 1 9.837184 TCGA-BP-4337 0.005479452 1 9.071214 TCGA-B0-4823 1.243835616 1 8.909733 TCGA-A3-3380 1.553424658 0 27.90318 TCGA-B0-5695 5.890410959 0 13.00429 TCGA-MM-A84U 1.917808219 0 6.026879 TCGA-B4-5835 0.043835616 0 4.951685 TCGA-B0-5094 0.912328767 1 12.15612 TCGA-AK-3426 2.424657534 1 5.39916 TCGA-CZ-4856 0.049315068 0 10.6857 TCGA-B0-5106 4.378082192 1 12.47959 TCGA-BP-4761 0.498630137 0 3.964946 TCGA-B0-5116 3.490410959 0 11.90614 TCGA-B2-4098 0.139726027 1 7.283905 TCGA-B8-4148 4.164383562 0 8.948891 TCGA-B0-4843 0.876712329 1 5.301522 TCGA-B8-5164 0.071232877 0 13.0557 TCGA-CW-5581 7.668493151 0 13.45315 TCGA-G6-A8L7 5.843835616 0 2.371167 TCGA-BP-5202 0.079452055 0 18.109 TCGA-CJ-5679 1.860273973 1 4.048481 TCGA-BP-4963 5.024657534 0 6.538478 TCGA-CZ-5466 1.876712329 0 8.069041 TCGA-AK-3440 7.849315068 0 6.070741 TCGA-B8-5552 2.865753425 0 9.294475 TCGA-BP-4167 7.446575342 0 5.783293 TCGA-B8-A54H 0.701369863 0 9.039011 TCGA-BP-5186 1.898630137 0 14.91575 TCGA-BP-4346 4.090410959 1 12.08186 TCGA-CJ-4895 3.287671233 1 8.189545 TCGA-DV-5574 5.523287671 0 12.52711 TCGA-CZ-5465 7.024657534 1 8.613441 TCGA-A3-3306 3.068493151 0 8.891085 TCGA-B0-5696 7.147945205 0 8.040021 TCGA-B8-5162 0.098630137 0 10.16797 TCGA-BP-4959 7.287671233 0 5.507991 TCGA-BP-4986 2.150684932 0 8.249064 TCGA-BP-4159 7.126027397 1 8.20944 TCGA-B0-4701 0.652054795 1 10.93379 TCGA-AK-3434 5.717808219 0 16.69713 TCGA-B8-A54E 2.490410959 0 5.529415 TCGA-BP-4960 5.950684932 0 4.872867 TCGA-EU-5904 1.509589041 0 23.5626 TCGA-B0-4824 4.539726027 1 5.798683 TCGA-A3-3358 3.580821918 0 6.841941 TCGA-B8-5165 2.019178082 0 18.30115 TCGA-B0-5700 4.904109589 0 6.346461 TCGA-CZ-5459 4.610958904 0 11.81061 TCGA-B0-5121 4.068493151 0 9.453106 TCGA-B8-5553 1.191780822 0 30.1836 TCGA-B0-5096 0.18630137 1 9.237164 TCGA-A3-3319 3.095890411 0 4.879899 TCGA-BP-4769 5.139726027 0 14.02639 TCGA-DV-5573 3.095890411 0 6.96892 TCGA-BP-4161 7.523287671 0 13.46862 TCGA-BP-4994 3.583561644 0 9.512555 TCGA-BP-4355 2.610958904 1 11.66325 TCGA-B0-5113 3.219178082 0 15.23375 TCGA-BP-4340 1.539726027 1 18.43933 TCGA-CW-6097 1.564383562 1 14.81775 TCGA-BP-4777 4.742465753 0 4.617842 TCGA-B0-4688 0.276712329 1 6.709922 TCGA-A3-3329 4.449315068 0 7.626388 TCGA-BP-4790 3.043835616 1 12.87144 TCGA-CZ-4863 5.282191781 0 7.820827 TCGA-BP-4962 4.890410959 0 6.895115 TCGA-CW-5589 6.515068493 0 13.13769 TCGA-CZ-4858 5.767123288 1 4.918952 TCGA-CZ-5461 0.904109589 1 9.909514 TCGA-B4-5378 0.479452055 0 23.34785 TCGA-A3-A6NN 0.008219178 0 18.59556 TCGA-BP-4343 5.238356164 1 7.286737 TCGA-B0-5691 9.4 0 22.96551 TCGA-CJ-4635 3.879452055 0 9.050866 TCGA-A3-A8OU 0 0 7.772709 TCGA-BP-4352 0.942465753 1 6.048399 TCGA-B0-4713 0.553424658 1 6.349818 TCGA-CJ-6031 5.221917808 0 9.522633 TCGA-CJ-4890 9.64109589 0 12.02952 TCGA-BP-5010 2.405479452 1 6.450099 TCGA-A3-3322 4.049315068 0 10.65429 TCGA-A3-3370 6.230136986 0 16.82362 TCGA-B0-4828 0.84109589 1 11.5142 TCGA-AK-3443 3.898630137 0 9.315995 TCGA-B0-4849 0.189041096 1 8.614598 TCGA-BP-4985 2.608219178 1 9.110152 TCGA-CJ-4885 9.454794521 0 16.40276 TCGA-CZ-5989 5.219178082 0 16.99137 TCGA-CZ-5456 6.635616438 0 6.401445 TCGA-CJ-4884 4.819178082 0 7.531741 TCGA-B0-4813 0.049315068 1 6.263992 TCGA-BP-4803 0.55890411 0 18.03972 TCGA-B4-5843 0.030136986 0 17.44296 TCGA-BP-4977 1.243835616 0 11.51657 TCGA-CJ-4892 4.167123288 0 9.02564 TCGA-B0-4844 0.857534247 1 5.848264 TCGA-BP-5178 5.238356164 1 8.7812 TCGA-AK-3425 9.15890411 0 5.972167 TCGA-CW-5587 6.098630137 0 13.21105 TCGA-A3-3343 2.589041096 0 20.88224 TCGA-A3-A8CQ 0.008219178 0 6.331119 TCGA-BP-4799 3.104109589 1 5.614394 TCGA-B0-4838 2.284931507 1 8.664622 TCGA-A3-A8OV 0.931506849 0 8.115008 TCGA-CZ-4865 0.454794521 1 8.492038 TCGA-BP-4326 4.452054795 1 17.64431 TCGA-BP-4771 0.443835616 1 6.904658 TCGA-B0-4945 5.876712329 1 10.246 TCGA-BP-4782 0.969863014 0 10.57046 TCGA-B0-5702 5.950684932 0 3.242007 TCGA-B8-5550 4.043835616 0 11.94734 TCGA-B8-A54J 1.446575342 0 10.67736 TCGA-CZ-5454 1.978082192 1 10.3733 TCGA-BP-4344 4.564383562 0 9.206742 TCGA-BP-4991 3.871232877 0 15.17459 TCGA-CJ-4634 9.583561644 0 10.5505 TCGA-CZ-4861 1.221917808 1 12.00352 TCGA-BP-4961 5.301369863 0 28.43253 TCGA-BP-4176 5.356164384 0 7.022192 TCGA-BP-5174 6.183561644 0 8.230981 TCGA-EU-5907 0.347945205 0 5.402032 TCGA-B8-5158 3.336986301 0 10.0246 TCGA-BP-4758 6.049315068 0 7.82557 TCGA-A3-A8OX 0 0 9.206377 TCGA-AK-3461 6.073972603 0 16.00926 TCGA-CW-5584 0.449315068 1 7.668282 TCGA-CJ-4902 4.164383562 0 12.23489 TCGA-AK-3458 3.2 0 14.12197 TCGA-BP-4335 1.301369863 1 8.36978 TCGA-B0-4814 0.460273973 1 16.96808 TCGA-B0-5119 4.252054795 0 13.82008 TCGA-MM-A563 1.619178082 0 7.629953 TCGA-BP-4775 5.049315068 0 10.11135 TCGA-BP-4965 5.126027397 0 13.11724 TCGA-CJ-4891 2.243835616 1 6.968858 TCGA-CJ-4868 1.769863014 1 10.05534 TCGA-CJ-4899 4.18630137 0 18.1959 TCGA-B0-4822 3.043835616 1 3.659455 TCGA-AK-3445 6.553424658 0 9.008362 TCGA-B0-4819 0.501369863 1 6.972963 TCGA-B0-4815 4.350684932 1 8.284337 TCGA-B2-3923 2.717808219 0 14.9994 TCGA-EU-5906 0.564383562 0 16.93557 TCGA-CJ-4920 0.380821918 1 9.423815 TCGA-B8-4619 1.432876712 0 8.69862 TCGA-A3-3324 3.249315068 0 8.865165 TCGA-CJ-4903 4.271232877 0 11.9257 TCGA-MM-A564 1.663013699 0 7.857102 TCGA-BP-5190 2.769863014 0 11.23259 TCGA-CJ-6028 4.452054795 1 9.561657 TCGA-CJ-4918 0.254794521 1 12.59931 TCGA-BP-5168 4.008219178 1 15.7272 TCGA-BP-4967 0.561643836 0 9.964851 TCGA-B2-4101 1.775342466 0 11.98675 TCGA-B4-5838 0.454794521 0 11.00512 TCGA-B4-5377 1 0 7.552821 TCGA-B0-4848 2.419178082 1 6.738472 TCGA-B0-5083 2.863013699 1 6.647079 TCGA-CJ-4881 5.517808219 0 6.113843 TCGA-CW-5585 7.147945205 0 13.07725 TCGA-BP-4331 6.723287671 1 6.449822 TCGA-G6-A8L6 0.857534247 1 7.688578 TCGA-BP-4975 3.926027397 0 13.97837 TCGA-B8-5546 1.383561644 0 11.91323 TCGA-B0-5097 1.821917808 0 9.753834 TCGA-BP-5169 0.528767123 0 5.039162 TCGA-CJ-4640 9.534246575 0 7.496902 TCGA-B0-4852 3.071232877 1 9.837138 TCGA-BP-5181 4.095890411 0 19.95691 TCGA-BP-4762 3.679452055 1 9.838961 TCGA-B0-5697 7.205479452 0 8.331732 TCGA-B0-5699 10.52328767 0 19.16674 TCGA-AK-3447 3.334246575 0 1.734232 TCGA-B0-5399 3.865753425 0 11.56595 TCGA-B0-5120 3.202739726 0 16.41764 TCGA-DV-A4W0 6.767123288 0 12.396 TCGA-CJ-4912 4.539726027 0 7.981214 TCGA-BP-4334 1.767123288 1 3.990338 TCGA-BP-4995 3.756164384 0 10.84589 TCGA-B0-4810 1.309589041 1 5.151166 TCGA-B2-5635 2.068493151 0 10.27252 TCGA-BP-5009 2.991780822 1 5.899792 TCGA-B8-A54D 2.273972603 0 10.33103 TCGA-BP-4982 2.778082192 0 18.45286 TCGA-B0-4836 3.391780822 1 12.01421 TCGA-CJ-4644 0.920547945 1 9.064341 TCGA-B0-5690 9.293150685 0 8.506829 TCGA-CJ-5678 1.57260274 1 8.340818 TCGA-BP-5196 2.789041096 0 9.494148 TCGA-CJ-5671 10.92328767 0 8.136427 TCGA-B0-4694 0.290410959 1 10.10509 TCGA-CJ-5675 10.78356164 0 6.592046 TCGA-BP-4789 4.079452055 0 12.96604 TCGA-CJ-4904 9.046575342 0 15.45947 TCGA-CZ-5464 5.830136986 0 7.912802 TCGA-B0-5081 0.991780822 1 5.287577 TCGA-BP-5200 2.912328767 0 9.832735 TCGA-DV-5567 5.490410959 0 17.61787 TCGA-B2-5639 2.747945205 1 8.553759 TCGA-B0-5117 4.405479452 0 3.218636 TCGA-BP-4969 4.915068493 0 5.147716 TCGA-CZ-5985 5.471232877 0 10.38654 TCGA-B8-A54F 1.421917808 0 27.65103 TCGA-AK-3453 6.934246575 0 5.097764 TCGA-BP-4989 0.323287671 0 4.868404 TCGA-A3-3387 1.690410959 0 11.46751 TCGA-DV-5566 3.830136986 0 8.47174 TCGA-CJ-4897 9.153424658 0 14.24982 TCGA-A3-3372 2.01369863 0 13.82257 TCGA-BP-4341 4.353424658 1 14.88229 TCGA-B0-5693 11.16164384 0 15.87064 TCGA-A3-3351 2.493150685 0 18.18825 TCGA-B8-A54G 0.145205479 0 8.774159 TCGA-A3-3349 3.794520548 0 13.95164 TCGA-BP-5194 1.117808219 0 15.15518 TCGA-B0-4703 0.498630137 1 9.496023 TCGA-B8-5163 2.252054795 0 7.927137 TCGA-BP-4807 0.578082192 0 10.74231 TCGA-A3-3320 4.131506849 0 12.62582 TCGA-BP-4776 1.126027397 0 8.895411 TCGA-A3-3378 1.726027397 0 12.69476 TCGA-BP-4971 4.073972603 0 5.857813 TCGA-BP-4972 4.115068493 0 10.75266 TCGA-CZ-5458 7.64109589 0 20.04734 TCGA-CJ-4905 4.098630137 0 14.70962 TCGA-BP-4353 1.02739726 1 19.62475 TCGA-BP-4970 1.18630137 0 14.23187 TCGA-B0-4847 2.17260274 1 4.976959 TCGA-BP-5007 3.123287671 0 17.57641 TCGA-B0-4846 3.287671233 1 9.80786 TCGA-B2-4099 2.663013699 0 3.861287 TCGA-BP-4797 3.032876712 0 9.698138 TCGA-B0-4827 2.424657534 1 12.81344 TCGA-BP-4964 5.101369863 0 11.30994 TCGA-AK-3460 6.871232877 0 23.15894 TCGA-CZ-4854 3.846575342 1 6.907728 TCGA-CJ-4872 0.893150685 0 9.714526 TCGA-CJ-5689 4.438356164 1 7.61448 TCGA-BP-4770 0.901369863 1 10.74466 TCGA-CZ-5467 0.2 1 14.98928 TCGA-AK-3454 2.394520548 0 3.800597 TCGA-B0-5107 2.539726027 1 11.21091 TCGA-BP-4760 6.468493151 0 11.76045 TCGA-BP-4173 5.18630137 0 9.517196 TCGA-B4-5832 0.424657534 0 14.63429 TCGA-CJ-4886 5.347945205 0 11.60152 TCGA-BP-4160 7.893150685 0 7.890623 TCGA-BP-5192 1.956164384 0 11.76887 TCGA-CJ-4908 4.194520548 0 13.56941 TCGA-B2-5641 1.797260274 0 7.478096 TCGA-CJ-4888 4.293150685 1 16.80108 TCGA-BP-4798 0.915068493 1 17.58667 TCGA-CJ-4876 5.356164384 0 8.105375 TCGA-BP-5198 1.652054795 0 19.33029 TCGA-CJ-4639 8.846575342 0 13.3678 TCGA-B0-5077 3.608219178 1 9.65341 TCGA-B0-5701 6.742465753 0 19.58478 TCGA-CZ-4862 8.961643836 0 10.68557 TCGA-BP-5175 2.553424658 0 2.623686 TCGA-BP-4976 4.471232877 0 15.39062 TCGA-A3-A6NL 1.887671233 0 8.868746 TCGA-B0-4816 3.756164384 1 14.89032 TCGA-CJ-6030 6.298630137 1 13.73101 TCGA-CZ-5470 1.057534247 0 10.87085 TCGA-BP-5001 3.224657534 0 5.325768 TCGA-CJ-4870 4.104109589 0 11.83416 TCGA-A3-3357 7.364383562 0 9.272925 TCGA-BP-4784 5.079452055 0 13.17128 TCGA-A3-3385 5.460273973 0 17.0973 TCGA-A3-3367 6.219178082 0 14.834 TCGA-BP-4162 8.421917808 0 9.439588 TCGA-BP-4170 6.419178082 1 9.124931 TCGA-CJ-4636 5.271232877 0 5.973549 TCGA-BP-5183 3.536986301 0 8.689306 TCGA-B0-4718 4.871232877 0 9.902922 TCGA-G6-A8L8 2.989041096 1 5.168133 TCGA-AK-3433 9.339726027 0 5.526094 TCGA-B0-4837 3.775342466 1 8.2464 TCGA-B0-4818 1.397260274 1 15.20809 TCGA-A3-A6NI 2.789041096 0 9.74051 TCGA-CW-5580 5.380821918 1 22.85155 TCGA-BP-4354 2.832876712 1 14.88899 TCGA-B8-A7U6 1.356164384 0 14.00804 TCGA-BP-5191 2.649315068 0 4.911757 TCGA-B8-4620 2.128767123 0 10.89372 TCGA-B0-5102 7.57260274 1 4.216488 TCGA-BP-4165 8.320547945 0 7.969757 TCGA-DV-5565 3.64109589 0 5.570752 TCGA-BP-4765 5.983561644 0 15.11396 TCGA-BP-4759 6.498630137 0 9.220758 TCGA-A3-3352 1.536986301 1 11.75238 TCGA-BP-4968 4.783561644 0 9.129564 TCGA-B2-A4SR 1.389041096 0 14.34006 TCGA-DV-5568 1.01369863 0 9.114178 TCGA-CJ-4874 6.254794521 0 9.721703 TCGA-CJ-4643 4.912328767 0 12.1901 TCGA-B0-4691 0.380821918 1 4.650958 TCGA-CJ-5682 10.23561644 0 12.7978 TCGA-B0-4839 4.490410959 1 6.745447 TCGA-BP-4983 3.871232877 0 6.187423 TCGA-BP-4787 1.315068493 1 6.797175 TCGA-CW-6093 8.619178082 0 13.20485 TCGA-AK-3428 10.21369863 0 17.84721 TCGA-BP-5201 2.605479452 0 7.564902 TCGA-A3-3382 1.57260274 0 9.224576 TCGA-B0-4833 6.536986301 1 7.945132 TCGA-CJ-4637 6.101369863 1 10.34213 TCGA-BP-4327 0.298630137 1 5.599213 TCGA-CZ-4857 3.923287671 1 12.24023 TCGA-BP-4781 5.698630137 0 7.681355 TCGA-BP-5173 0.169863014 1 7.078021 TCGA-BP-5006 2.301369863 0 8.35963 TCGA-DV-5569 0.97260274 0 9.694596 TCGA-BP-5176 4.356164384 1 10.13353 TCGA-B0-4845 5.44109589 1 8.701721 TCGA-BP-4974 0.578082192 1 8.203424 TCGA-BP-4330 5.17260274 0 17.23465 TCGA-CJ-6027 9.904109589 1 5.935736 TCGA-B0-5709 10.88767123 0 16.17641 TCGA-B0-5075 1.745205479 1 7.128112 TCGA-B8-5549 0.531506849 0 19.48633 TCGA-CJ-5676 11.14246575 0 10.64911 TCGA-B0-5104 7.539726027 1 9.509035 TCGA-CJ-4894 2.304109589 1 12.72476 TCGA-B0-4712 3.663013699 1 3.446981 TCGA-CW-5590 2.945205479 1 9.024535 TCGA-B0-5713 7.621917808 0 11.70762 TCGA-B0-5110 5.504109589 0 10.80661 TCGA-CZ-5462 0.852054795 1 8.729015 TCGA-DV-5576 1.991780822 1 16.89046 TCGA-BP-5185 3.101369863 0 2.70997 TCGA-B0-5400 4.747945205 0 4.638419 TCGA-CJ-4889 5.331506849 0 10.40809 TCGA-CJ-4900 4.695890411 1 13.84232 TCGA-BP-4795 1.698630137 0 10.87358 TCGA-3Z-A93Z 1.054794521 0 7.380349 TCGA-DV-A4VZ 1 0 4.333005 TCGA-BP-4756 1.024657534 0 10.62814 TCGA-BP-4981 3.005479452 1 7.178958 TCGA-A3-3328 3.794520548 0 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