AKT_MTOR 79 YWHAQ YWHAZ YWHAE YWHAB SFN YWHAG YWHAH EIF4EBP1 AKT1 AKT2 BCL2L1 BCL2 BECN1 BNIP3 CAB39 CAMKK2 CUL4A DAPK1 DDB1 DDIT4 DEPTOR PRKDC DRAM1 DUSP1 DUSP16 DUSP6 DUSP10 EIF4B EIF4E MAPK3 MAPK1 MAPK6 FKBP8 FOXO1 FOXO3 GSK3B HSP90AA1 IKBKB MAPKAP1 MLST8 MTOR NAA10 PDCD4 PDPK1 PHLDA3 PIK3C3 PIM1 PIM2 PIM3 AKT1S1 PRDX1 PRDX2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RBX1 RHEB RICTOR RPTOR RPS6KA1 RPS6KA3 RPS6KA2 RPS6KB1 RPS6KB2 SESN1 SESN2 STK11 STRADA MAP3K7 TSC1 TSC2 BTRC FBXW11 ABR CASP3 APOPTOSIS_GENES 190 ALAS1 ALDOA APAF1 ATP5A1 ATP5B ATP5C1 ATP5G1 BACH1 BAD BAK1 BAX BBC3 BCL2 BCL2A1 BCL2L2 BECN1 BID BIK BIRC2 BIRC3 BIRC5 BMF BNIP3 BCL2L11 CA9 CCNG2 CDK6 CFLAR CITED2 COX4I2 COX5A COX5B COX6A1 COX7A2 CTBP1 CTBP2 CTSB DDIT4 DFFB DRAM1 E2F1 E2F3 EGLN1 EGLN2 EGLN3 EGR2 ELK1 ENO1 ESRRA FBXO45 FECH FOXO1 FOXO3 FTH1 FUBP1 G0S2 GAPDH GCLC GCLM GLS GLS2 GPI HIF1A HIPK2 HK2 HMOX1 HRK HSP90AA1 HSP90AA2 HSP90AB1 IDH3A IGFBP1 IGFBP3 IKBKB KCNIP3 KLF8 LDHA LMNA LONP1 PIDD MAFG MAFK MAX MCL1 MDM2 MLST8 MLX MLXIP MRPS12 MT-CO2 MTOR MXD1 MXI1 MYC NDUFAF2 NDUFS8 NFE2L2 NFKB1 NFKBIA NOS2 NOTCH1 NPM1 NPM2 NPM3 NRF1 KAT2B PDCD4 PDK1 PDK3 PDK4 PFKFB3 PFKFB4 PFKM PGK1 PHLDA3 PMAIP1 PPARGC1A PRDX1 PRDX2 PRDX3 PRKAB1 PRKAB2 PTEN PYCARD RB1 RPTOR RRM2B SCO2 SDHB SDHC SDHD SESN1 SESN2 SIRT1 SIVA1 SLC1A5 SLC2A1 SLC2A4 SLC38A5 SOD1 SOD2 SRXN1 STAT3 STAT5A STAT5B SURF1 TFAM TFB1M TFB2M C12orf5 TKT TNFAIP3 TPI1 TSC2 TXN TXNIP TXNRD1 VDAC1 VDAC3 VEGFA XAF1 XIAP YY1 NKRF CDKN2A CDKN1A CDKN1B TP53 TP73 LAMA1 LAMA2 PRKDC C9orf3 BCL2L1 CDC20B CYCS CASP3 CASP7 CASP8 CASP9 CCND1 FASLG MCM7 MIR17HG MIR23A MIR34A PANK1 PKM PPARGC1B SIAH1 CASPASES 77 YWHAQ YWHAZ YWHAE YWHAB SFN YWHAG YWHAH ABL1 ACHE AFP AK2 AKT1 AKT2 ANP32A APAF1 APIP AVEN BAX BCL2 BIRC5 BIRC6 BIRC7 BCL2L11 CAPN2 CCS CDK1 CRADD CSE1L CYCS CASP2 CASP3 CASP6 CASP7 CASP9 CCNB1 CCND1 DIABLO DYRK1A ENDOG MAPK3 MAPK1 MAPK6 GSPT1 HAX1 LAMTOR5 HSPA1A HSPA1B HSPA1L HSP90AA1 HSPB1 IKBKB ING4 PIDD NAIP NOD1 PPP1CA PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKCZ PTMA RIPK1 RNF41 TXN XIAP ABR MAPK11 MAPK12 MAPK13 MAPK14 BID AIFM1 CASP8 HIF1 19 CITED2 CUL2 EGLN1 EGLN2 EGLN3 HIF1A HIF1AN HSP90AA1 OS9 GNB2L1 RBX1 SART1 STAT3 TCEB1 TCEB2 VEGFA VHL CDKN2A EP300 MITOCH_METABOLISM 382 ACACA ACACB ACAD9 ACLY ACO1 ACO2 ACSS1 ACSS2 AIFM1 AK1 AK2 AKT1 AKT2 ALAD ALAS1 ALAS2 ALDOA ALDOB ALDOC SLC25A4 SLC25A5 SLC25A6 APBB1 ANAPC1 ANAPC10 ANAPC11 CDC26 ANAPC13 ANAPC2 CDC27 ANAPC4 ANAPC5 CDC16 ANAPC7 CDC23 ATM ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5L ATP5O ATP5S ATPAF1 ATPAF2 ATPIF1 BAD BAK1 BARD1 BAX BAZ1B BCL2L1 BCL2 BCL2L2 BID BLVRA BRCA1 BCL2L11 CAPN1 CCL19 COX10 COX15 COX17 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CPOX CS CTSB CTSL1 CTSL2 CTSL3P CTSS CYC1 CYCS DFFA DHODH DLAT DLD DLST ECSIT ENO1 ENO2 ENO3 NOS1 NOS2 NOS3 EYA1 EYA3 FAM175A FASN FBP1 FBP2 FECH FH FZR1 G6PD GABPA GAPDH GAPDHS GCK GLS GLS2 GLUD1 GLUD2 GLUL GPI GPT GPT2 GZMA HIST2H2AC H2AFX H6PD HCCS HK1 HK2 HK3 HMBS HRK IDH1 IDH2 IDH3A IDH3B IDH3G IGFBP1 KAT5 XRCC6 LDHA LDHB LDHC LONP1 PIDD MCL1 SLC16A1 SLC16A3 SLC16A4 MDC1 MDH1 ME1 ME3 MRE11A MRPS12 MT-ATP6 MT-ATP8 MT-CO1 MT-CO2 MT-CO3 MT-CYB MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND4L MT-ND5 MT-ND6 MTERFD3 NBN NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA13 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NME1 NME2 NME3 NME4 NME5 NME6 NME7 NRF1 OGDH PDHA1 PDHA2 PDHB PDHX PDK1 PDK2 PDK3 PDK4 PDP1 CASC5 PFKP PFKL PFKM PFKFB1 PFKFB2 PFKFB3 PFKFB4 PGAM1 PGAM2 PGAM4 PGD PGK1 PGK2 PGLS PKLR PKM PMAIP1 PML POLRMT PPAT PPIA PPM1D PPOX PPP1CA PPP1CB PPP1CC PRDX3 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3 PRPS1 PRPS1L1 PRPS2 PYCARD RAD50 RIPK3 RNF168 RNF8 RPE RPIA RRM1 RRM2 RRM2B RUNX3 SCO1 SCO2 SDHA SDHAF1 SDHAF2 SDHB SDHC SDHD SHC1 SIRT1 SIRT3 SIVA1 SLC1A5 SLC25A1 SLC25A10 SLC25A11 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC38A3 SLC38A5 SMARCA5 SNAP23 SOD1 SOD2 SRXN1 STAT3 STX4 STXBP4 SUCLG1 SUCLG2 SURF1 TACO1 TALDO1 TFAM TFB1M TFB2M C12orf5 TKT TKTL2 TKTL1 TMEM70 TP53BP1 TPI1 TRIP12 TXN TXN2 TXNIP TXNRD2 UBE2N UCP1 UCP2 UCP3 SLC25A27 SLC25A14 SLC25A47 UQCR10 UIMC1 UQCR11 UROD UROS USP3 VAMP2 VDAC1 VDAC2 VDAC3 WASF1 MT-RNR2 CASP3 GCLC GLRX DNA2 MIR34A MT-TA MT-TC MT-TD MT-TE MT-TF MT-TI MT-TK MT-TL1 MT-TM MT-TN MT-TP MT-TQ MT-TS1 MT-TT MT-TV MT-TW MT-TY RNA5-8S1 MOMP_REGULATION 102 YWHAQ YWHAZ YWHAE YWHAB SFN YWHAG YWHAH AKT1 AKT2 BAD BAK1 BAX BBC3 BCL2L1 BCL2 BCL2A1 BCL2L12 BCL2L2 BID BMF BRCC3 BCL2L11 C1QBP CAPN1 CAPN2 CDK1 CISH CSNK2A2 CSNK2A1 CSNK1A1 CSNK1E CUL1 CUL2 DYNLL1 DYNLL2 MAPK3 MAPK1 MAPK6 FKBP8 G0S2 GCK GSK3B GZMB HUWE1 HRK HSP90B1 IGFBP1 MAPK8 MAPK9 MAPK10 XRCC6 MCL1 MIF MLX MLXIP NDRG1 NMT1 NR4A1 PAK1 PIM1 PIM2 PIM3 PMAIP1 PPP1CA PPP1CB PPP1CC PPP3CB PPP3R1 PRKACA PRKACB PRKACG PRKCA PRKCZ PYCARD GNB2L1 RAF1 RBX1 RPS6KA1 RPS6KA3 RPS6KA2 RPS6KB1 RPS6KB2 SIVA1 SKP1 TCEB1 TCEB2 TCEB3 TMBIM6 USP9X VDAC1 VDAC2 VDAC3 WASF1 BTRC FBXW11 ABR MT-RNR2 TP53 BECN1 CASP2 CASP3 CASP8 TNF_RESPONSE 105 YWHAQ YWHAZ YWHAE YWHAB SFN YWHAG YWHAH MAP3K5 BAG4 BIRC2 BIRC3 CA9 CFLAR CHUK CUL1 CUL3 CYBA CYBB CYLD CASP8 DAB2IP DIABLO DUSP1 DUSP16 DUSP6 DUSP10 FADD FLAD1 FTH1 FTL GCLC GCLM GLRX GPX1 GPX2 GSR GSS HIP1 HSP90AA1 HTRA2 HTT IFT57 IKBKB IKBKG ITCH MAPK8 MAPK9 MAPK10 KEAP1 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPK11 MAPK12 MAPK13 MAPK14 NCF1 NCF2 NFKB1 NFKBIA NOX1 NOX3 NOX4 NOX5 NOXA1 NOXO1 PIN1 PRKACA PRKACB PRKACG PPP2CB PPP2R1A PPP5C PPP6C RAC1 RAC2 RBX1 RELA RFK RIPK1 RIPK3 RNF11 SKP1 SOCS1 TAB2 TAB3 MAP3K7 TAX1BP1 TNF TNFAIP3 TRADD TRAF2 TRAF6 TXN TXNRD1 BTRC FBXW11 CIAPIN1 TNFRSF1A BECN1 CASP2 CASP3 CASP6 CASP7 APC 15 ANAPC1 ANAPC2 CDC27 ANAPC4 ANAPC5 CDC16 ANAPC7 CDC23 ANAPC10 ANAPC11 CDC26 ANAPC13 CDC14A CDC20 FZR1 APOPTOSIS_ENTRY 10 AKT1 ATM ATR CHEK1 CHEK2 E2F1 MDM2 NBN CDKN2A TP53 CDC25 2 CDC25C CHEK2 CYCLINA 6 CDK2 CCNA1 CCNA2 RBL1 RBL2 CDKN1B CYCLINB 7 ATM CDK1 MDM2 PKMYT1 CCNB1 CCNB2 CCNB3 CYCLINC 2 CDK3 CCNC CYCLIND 9 AKT1 CDC37 CDK4 CDK6 GSK3B HSP90AA1 CCND1 CCND2 CCND3 CYCLINE 7 CDK2 CDKN3 CCNE1 CCNE2 RBL1 RBL2 CDKN1B CYCLINH 3 CDK7 MNAT1 CCNH E2F1 19 ATM ATR CHEK2 CREBBP TFDP1 E2F1 EP300 HDAC1 KAT2B GTF2H1 GTF2H2 GTF2H2B GTF2H2C GTF2H2D GTF2H3 GTF2H4 GTF2H5 TOPBP1 RB1 E2F4 8 TFDP2 E2F4 E2F5 HDAC1 SIN3B SUV39H1 RBL1 RBL2 E2F6 13 EHMT2 TFDP1 TFDP2 E2F6 E2F8 EED EHMT1 EPC1 EZH2 CBX3 MAX MGA SIN3B E2F1_TARGETS 130 ACTG1 ACTN4 APAF1 DBF4 ATM ATP5J AURKB AXIN2 BBC3 BCL2 BCL2L11 BIRC5 BMI1 BRCA1 CASP3 CASP7 CASP8 CASP9 CBX5 CCND3 CDK1 CDC25A CDC6 CDCA4 CDCA7 CDKN2C CDT1 CHEK2 NCAPD2 CSDA CYC1 COX4I1 CCNE1 CCNE2 DDX11 DHFR DIRAS3 DNMT1 E2F1 E2F2 E2F6 E2F7 E2F8 EED EIF2AK2 EXOSC8 EZH2 FGFR2 FHIT FOXO1 FOXO3 FSHR GAB2 GMNN H19 HRK ISYNA1 JMY LGALS1 MCAM MCL1 MCM10 MCM3 MCM7 MCM8 MELK MXD3 MYB MYBL2 MYC MYCN NPAT NRP1 DUSP2 PCNA PFKFB1 PFKFB2 PFKFB3 PFKFB4 PMAIP1 PNRC2 POLA1 POLA2 PPARG PPP1R13B PTGS2 PURA RAD51AP1 RBBP4 RBBP8 RBL1 RBM25 RPA2 RPL32 RPL8 RRM2 SERPINE1 SIVA1 SKP2 SNRPE SNX19 SSR4 STMN1 SUZ12 TERT ACOT13 TK1 TOP2A TOPBP1 TP53 TP53BP1 TP53IN91 TP73 UBB UNG UHRF1 UXT WWOX ZNF451 CES1 CES2 CES3 CES4A CES5A CCNA2 CCNB1 CDKN2A CDKN1A CDKN1B PLAU E2F2_TARGETS 35 BCL2 BIRC5 CCND3 CDK1 CDC6 CDCA4 CDCA7 CDKN2C CDT1 NCAPD2 CCNE1 CCNE2 DHFR E2F1 ECE1 EED EZH2 GAB2 GMNN MCM7 MCM8 MELK MYBL2 MYC MYCN NPAT PCNA PPP1R13B RBL1 TERT TP53BP1 UXT CCNA2 CCNB1 CDKN2A E2F3_TARGETS 51 DBF4 ATM BIRC5 BUB1 CCNB2 CCND3 CCNE1 CDK1 CDC20 CDC25A CDC6 CDCA4 CDCA7 CDT1 NCAPD2 CCNE2 DHFR E2F1 EED EZH2 GAB2 GMNN KPNA2 MCM6 MCM7 MCM8 MELK MYBL2 MYC MYCN NPAT PCNA POLA1 POLA2 PPARG PPP1R13B RBL1 RRM1 RRM2 TERT TK1 TP53BP1 TP73 TYMS UXT CCNA2 CCNB1 MIR17HG CDKN2A CDKN1A POLD3 E2F4_TARGETS 100 E2F4 ACR ATM AURKB BARD1 BCL2 BIRC5 BRCA1 BTRC BUB1 CBX5 CCNB2 CDK1 CDC20 CDC25A CDC6 CDCA4 CDCA7 CDKN2C CDT1 CHEK1 CHEK2 CLSPN CSTF1 CSTF3 DDX11 DHFR DIRAS3 DBF4B E2F1 E2F7 E2F8 EED ESR1 EXOSC8 EZH2 FBXO5 FGFR1 GMNN HOXA3 JPH2 NDC80 KPNA2 MAD2L1 MCM10 MCM3 MCM5 MCM6 MCM7 MCM8 METAP2 MLH1 MRPL27 MSH2 MTHFD1 MYBL2 MYC MYCN NEK2 NPAT PBK PCNA PFKFB1 PFKFB2 PFKFB3 PFKFB4 PLK1 POLA1 POLA2 PPARG PRKDC PSMA4 RAD51AP1 RAD54L RBBP4 RBBP8 RBL1 RQCD1 RRM1 RRM2 SLC25A14 SLC3A2 SPAG7 SRPR STMN1 TERT TK1 TOP2A TOPBP1 TP73 TRIM55 TYMS UNG UXT ZNF451 ZNF83 CCNA2 CCNB1 CDKN2A POLD3 E2F5_TARGETS 6 BIRC5 ESR1 FSHR GMNN MYC TERT E2F6_TARGETS 34 E2F6 BRCA1 BRD7 CBX5 CCNB2 CDK1 CDC25A CDC6 CHEK2 CYC1 DDX11 E2F1 EXOSC8 H19 MCM3 MYC PCNA POLA1 POLA2 RAD51AP1 RBBP4 RBBP8 RRM1 RRM2 SPAG7 TK1 TUBA1A TYMS UXT WDR36 ZNF451 ZNF83 CCNA2 POLD3 E2F7_TARGETS 4 CCNE1 CDC6 E2F1 E2F8 E2F8_TARGETS 5 CCNE1 CDC6 E2F1 CCNA2 CCNB1 INK4 3 SERTAD1 CDKN2B CDKN2A P21CIP 3 AKT1 PCNA CDKN1A P27KIP 2 AKT1 CDKN1B RB 12 HDAC1 CBX3 PPP1CA PPP1CB PPP1CC PPP1R1A PPP1R1C PPP1R2 PPP1R3D SUV39H1 ARID1A RB1 WEE 2 CHEK1 WEE1 CELL_CYCLE 82 ANAPC1 ANAPC10 ANAPC11 CDC26 ANAPC2 CDC27 ANAPC4 ANAPC5 CDC16 ANAPC7 CDC23 CDC14A CDC20 CDC25A CDC25B CDC25C CDC45 CDC6 CDC7 CDK1 CDK2 CDK4 CDK6 CDK7 CDT1 CDKN1A CDKN1B CDKN1C CCNA1 CCNB1 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCNH DBF4 CDH1 E2F1 E2F4 E2F5 FBXO5 GINS1 GINS2 GINS3 GINS4 CDKN2A CDKN2B CDKN2C CDKN2D MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 ORC1L ORC2L ORC3L ORC4L ORC5L ORC6L POLA1 POLA2 PRIM1 PRIM2 RB1 RPA1 RPA2 RPA3 RAD21 SMC1A SMC1B SMC3 STAG1 STAG2 STAG3 TIMELESS TIPIN WEE1 RBL1 G1_CC_PHASE 25 CDC25A CDK2 CDK4 CDK6 CDK7 CDKN1A CDKN1B CDKN1C CCND1 CCND2 CCND3 CCNE1 CCNE2 CCNH E2F1 E2F4 E2F5 CDKN2A CDKN2B CDKN2C CDKN2D MNAT1 RB1 WEE1 RBL1 G1_S_CHECKPOINT 32 AKT1 AKT2 AKT3 ATM ATR BMI1 BRCA1 CAND1 CHEK1 CHEK2 CTBP1 CTBP2 RBBP8 CUL1 E2F1 FOXO1 FOXO3 MAX ZBTB17 MYC PARP1 PARP2 KAT2A KAT2B EP300 RB1 SKP1 SKP2 BTRC RBL1 TP53 RBX1 G2_CC_PHASE 5 CDC25B CDC25C CDK1 CCNB1 WEE1 G2_M_CHECKPOINT 68 YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ ABL1 ATM ATR ATRIP AURKA BRCA1 MCPH1 CAND1 CREBBP CDK1 CHEK1 CHEK2 CLSPN CTBP1 CTBP2 RBBP8 CUL1 CCNB1 FANCD2 GADD45A H2AFX HIPK2 HSPC2 ITCH MAPK8 MAPK9 MAPK10 MDC1 MDM2 MRE11A RE11B NBN PARP1 PARP2 KAT2A KAT2B EP300 PKMYT1 PLK1 RAD17 RAD50 RAD51 RAD51L1 RAD51C RAD51L3 RBX1 RAD21 SIAH1 SIAH2 SKP1 SKP2 SMC1A SMC1B SMC3 STAG1 STAG2 STAG3 TOPBP1 YAP1 BTRC TP53 TP73 M_CC_PHASE 24 ANAPC1 ANAPC10 ANAPC11 CDC26 ANAPC2 CDC27 ANAPC4 ANAPC5 CDC16 ANAPC7 CDC23 CDC14A CDC20 CDK1 CCNB1 CDH1 FBXO5 RAD21 SMC1A SMC1B SMC3 STAG1 STAG2 STAG3 S_CC_PHASE 46 CDC25A CDC45 CDC6 CDC7 CDK1 CDK2 CDK7 CDT1 CDKN1A CDKN1B CDKN1C CCNA1 CCNH DBF4 E2F1 E2F4 E2F5 GINS1 GINS2 GINS3 GINS4 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 ORC1L ORC2L ORC3L ORC4L ORC5L ORC6L POLA1 POLA2 PRIM1 PRIM2 RB1 RPA1 RPA2 RPA3 TIMELESS TIPIN WEE1 RBL1 S_PHASE_CHECKPOINT 45 ABL1 ATM ATR ATRIP BRCA1 MCPH1 CAND1 CHEK1 CHEK2 CLSPN CUL1 C19orf40 FANCM H2AFX TELO2 HUS1 MDC1 MRE11A RE11B NBN PARP1 PARP2 PPP5C PRKCD RAD1 RAD17 RAD50 RAD9A RAD9B RBX1 RPA1 RPA2 RPA3 RAD21 SKP1 SKP2 SMC1A SMC1B SMC3 STAG1 STAG2 STAG3 TIMELESS TIPIN BTRC SPINDLE_CHECKPOINT 28 ANAPC1 ANAPC10 ANAPC11 CDC26 ANAPC2 CDC27 ANAPC4 ANAPC5 CDC16 ANAPC7 CDC23 AURKB BIRC5 BRCA1 BUB1 BUB3 BUB1B CDCA8 CDC20 MAPK1 INCENP MAD1L1 MAD2L1 MAD2L2 TTK PARP3 PTTG1 ESPL1 DNA_REPAIR 171 ALKBH2 ALKBH3 APEX1 APEX2 DCLRE1C BARD1 BLM BRCA1 BRCA2 MCPH1 CDK5 CDK7 CETN2 CHTF18 CSNK2A1 CSNK2A2 CSNK2B ERCC8 ERCC6 CUL4A CUL4B DDB1 DDB2 PRKDC DNA2 SHFM1 EME1 ERCC1 EXO1 C17orf70 C1orf86 C19orf40 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCI BRIP1 FANCL FANCM PALB2 FEN1 GADD45A GEN1 HELQ HES1 HSPC2 XRCC6 XRCC5 LIG1 LIG3 LIG4 MBD4 C6orf61 C20orf154 MDC1 MGMT MLH1 MLH3 MNAT1 MPG MRE11A RE11B MSH2 MSH3 MSH6 MUS81 MUTYH NBN NEDD4 NEDD8 NEIL1 NEIL2 NEIL3 NTHL1 OGG1 PARG PARP1 PARP2 PARP3 PCNA PMS1 PMS2 PNKP POLB POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLH POLI POLK POLL POLM POLN POLQ REV3L RAD18 RAD23A RAD23B SHPRH RAD50 RAD51 RAD51L1 RAD51C RAD51L3 RAD52 RAD54B RAD54L UBE2A UBE2B RBX1 RECQL5 REV1 RFC1 RFC2 RFC3 RFC4 RFC5 RMI1 RNF8 RPA1 RPA2 RPA3 SFPQ SLX1A BTBD12 SMARCAL1 SMC1A SMC1B SMC3 SMC5 SMC6 SMUG DCLRE1B PTTG1 TDG TDP1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KAT5 TOP3A DNTT WDR48 UBE2V2 UBE2N UBE2T UNG USP1 WRN XAB2 XPA ERCC3 XPC ERCC2 ERCC4 ERCC5 XRCC1 XRCC2 XRCC3 XRCC4 DR_REGULATORS 137 YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ ABL1 AKT1 AKT2 AKT3 ATM ATR ATRIP AURKA AURKB BIRC5 BMI1 BRCA1 MCPH1 BUB1 BUB3 BUB1B CDCA8 CAND1 CREBBP CHEK1 CHEK2 CSNK2A1 CSNK2A2 CSNK2B CLSPN CTBP1 CTBP2 RBBP8 CUL1 MAPK1 C19orf40 FANCD2 FANCM FOXO1 FOXO3 GADD45A GSK3B H2AFX TELO2 HIPK2 HUS1 INCENP ITCH MAPK8 MAPK9 MAPK10 MAD1L1 MAD2L1 MAD2L2 MAX MDC1 MDM2 ZBTB17 TTK MRE11A RE11B MYC MEN1 NBN PARP1 PARP2 PARP3 KAT2A KAT2B EP300 PRKCA PRKCB PRKCG PRKCD PRKCE PRKCZ PRKCH PRKCQ PRKCI PKMYT1 PLK1 PPP2R4 PPP2CA PPP2R5C PPP2R5D PPP2R2B PPP2R5A PPP2R2A PPP2R5E PPP2R1B PPP2R1A PPP2R2C PPP2R5B PPP2R3A PPP2CB PPP2R2D PPP2R3B PPP5C RAD1 RAD17 RAD50 RAD51 RAD51L1 RAD51C RAD51L3 RAD9A RAD9B RBX1 RNF8 RPA1 RPA2 RPA3 RAD21 SIAH1 SIAH2 SKP1 SKP2 SMC1A SMC1B SMC3 SNAI1 STAG1 STAG2 STAG3 PTTG1 ESPL1 TIMELESS TIPIN TNKS TOPBP1 TP53BP1 YAP1 BTRC RBL1 TP53 TP73 HR 55 BARD1 BLM BRCA1 BRCA2 MCPH1 CSNK2A1 CSNK2A2 CSNK2B DNA2 SHFM1 EME1 EXO1 BRIP1 PALB2 GEN1 HELQ HSPC2 C6orf61 C20orf154 MDC1 MRE11A RE11B MUS81 NBN PARG PARP1 PARP2 PARP3 POLH POLN RAD50 RAD51 RAD51L1 RAD51C RAD51L3 RAD52 RAD54B RAD54L RECQL5 RMI1 RPA1 RPA2 RPA3 SFPQ SMARCAL1 SMC1A SMC1B SMC3 SMC5 SMC6 KAT5 TOP3A WRN XRCC2 XRCC3 MMR 18 EXO1 LIG1 MBD4 MLH1 MLH3 MSH2 MSH3 MSH6 PCNA PMS1 PMS2 POLD1 POLD2 POLD3 POLD4 RPA1 RPA2 RPA3 NER 54 CDK7 CETN2 CHTF18 CSNK2A1 CSNK2A2 CSNK2B ERCC8 ERCC6 CUL4A CUL4B DDB1 DDB2 ERCC1 FANCM GADD45A LIG1 LIG3 MNAT1 NEDD8 PCNA POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLK RAD23A RAD23B RBX1 RFC1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 UBE2T XAB2 XPA ERCC3 XPC ERCC2 ERCC4 ERCC5 XRCC1 BER 50 APEX1 APEX2 CDK5 FEN1 GADD45A LIG1 LIG3 MBD4 MLH1 MPG MSH2 MSH6 MUTYH NEDD4 NEIL1 NEIL2 NEIL3 NTHL1 OGG1 PARG PARP1 PARP2 PCNA PNKP POLB POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLQ RAD23A RAD23B RECQL5 RFC1 RFC2 RFC3 RFC4 RFC5 SMUG TDG TDP1 UNG WRN XPC ERCC5 XRCC1 SSA 8 EME1 ERCC1 MSH2 MSH3 MUS81 RAD52 SLX1A BTBD12 TLS 28 BLM C17orf70 C1orf86 C19orf40 FANCA FANCB FANCC FANCE FANCF FANCG BRIP1 FANCL FANCM HES1 PCNA POLH POLI POLK REV3L RAD18 SHPRH UBE2A UBE2B REV1 WDR48 UBE2V2 UBE2N USP1 A_NHEJ 19 RBBP8 ERCC1 EXO1 LIG1 LIG3 MRE11A RE11B NBN PARP1 POLD1 POLD2 POLD3 POLD4 POLL POLN RAD50 WRN ERCC4 XRCC1 C_NHEJ 16 DCLRE1C PRKDC XRCC6 XRCC5 LIG4 MDC1 PARG PARP1 PARP3 PNKP POLL POLM RNF8 PTTG1 DNTT XRCC4 DR 3 ALKBH2 ALKBH3 MGMT FANCONI 41 BLM BRCA1 BRCA2 EME1 ERCC1 C17orf70 C1orf86 C19orf40 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCI BRIP1 FANCL FANCM PALB2 HELQ HES1 HSPC2 C6orf61 C20orf154 MUS81 POLH POLL POLN POLQ REV3L RBX1 REV1 SMARCAL1 DCLRE1B KAT5 TOP3A WDR48 UBE2T USP1 ERCC4 ADHERENS_JUNCTIONS 33 CDH1 CDH2 CDH3 CDH4 ACTA1 ACTA2 ACTB ACTC1 ACTG1 L1CAM CDH5 CTNNB1 CSNK1A1 AXIN1 DVL1 APC LEF1 TCF4 CTNNA1 CTNND1 FMN1 PTPN11 CSK TCF3 CSNK2A1 PPP1CA PPP1CB PPP1CC FRAT1 CHUK SRC FYN TCF12 CELL_CELL_ADHESIONS 107 CDH1 OCLN CLDN7 F11R TJP3 GJB3 CLDN4 DSP PKP3 CDH2 CDH3 CDH4 MPP5 MPDZ ITGB1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 CXADR TJP1 TJP2 CLDN3 PARD6A SMURF1 RHOA L1CAM CDH5 CTNNB1 CSNK1A1 AXIN1 DVL1 APC LEF1 TCF4 PARD3 RAC1 RHOB CTNNA1 CTNND1 FMN1 PTPN11 CSK JAM2 JAM3 CLDN1 CLDN2 CLDN5 CLDN8 CLDN14 CLDN16 CLDN19 CLDN18 WNK4 MTDH GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJC1 GJD2 JUP PKP4 DSG2 PKP2 MLLT4 CGN PVRL1 CAV1 TSPAN3 CLDN11 PRKCA PRKCG PRKCE PRKCB SRC PRKCZ TCF3 GJB5 DSC2 PKP1 CSNK2A1 PPP1CA PPP1CB PPP1CC FRAT1 CHUK DSC1 DSC3 DSG1 DSG3 ERBB2 ARHGDIA VIM KRT18 KRT14 KRT8 KRT5 KRT1 FYN JUNB SMURF2 TCF12 CELL_MATRIX_ADHESIONS 73 FN1 ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGA10 ITGA11 ITGAD ITGAE ITGAL ITGAM ITGAX ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 COL1A2 COL4A1 COL2A1 LAMA1 LAMA4 LAMA5 COL1A1 COL5A1 COL6A3 COL6A2 VTN LAMA2 LAMA3 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 PXN VCL TLN1 TLN2 ACTN1 ACTN2 ACTN4 PTK2 PTK2B ABL1 CRK BCAR1 ZYX SRC CSK FYN JUNB FBLN1 FBLN2 ELN COL3A1 CYTOSKELETON_POLARITY 154 CRB3 VIM MPP5 CDC42 CASK LIN7C C16orf70 INADL MPDZ ACTA1 ACTA2 ACTB ACTC1 ACTG1 PARD6A RHOA KRT14 KRT18 KRT19 ROCK1 ROCK2 CFL1 LIMK1 RAC1 PAK1 PAK2 PAK3 WASF1 WASF2 WAS WASL ACTR2 ACTR3 CDC42BPA MAP3K11 PAK4 LIMK2 PRKCZ CDC42EP2 CDC42EP3 CDC42SE1 CYFIP2 BAIAP2 ARFIP2 PIP5K1A MCF2L NCK1 NCKAP1 RALBP1 ABR ARHGAP1 ARHGAP9 ARHGAP12 ARHGAP24 SRGAP3 BCR RACGAP1 ARHGAP32 CHN2 ARHGDIA ARHGDIB CASP1 CASP3 EZR VAV1 VAV2 ARHGEF2 ARHGEF4 LCP2 ZAP70 TIAM1 MCF2 ECT2 TNK2 PGGT1B ARHGDIG BNIP2 DLC1 ARHGAP5 RASA1 FYN ARHGAP31 ARHGAP17 FGD1 DOCK6 DOCK9 DOCK11 FGD4 SPATA13 DEF6 ARHGEF3 ARHGEF10L RTKN RHPN2 PKN1 PLCE1 DIAPH1 DIAPH3 RHOB ARHGEF1 PLD1 RAP1GDS1 KIFAP3 NGEF ARHGEF12 PTK6 MYO9B ARHGAP26 MYH1 ARHGAP35 RDX MSN DIAPH2 RHPN1 MAP3K10 MAP3K7 PARD6B PARD6G PIP5K1B PIP5K1C DSTN MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYH10 MYH11 MYH13 MYH14 MYH15 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL6B MYL7 MYL10 MYL12A MYL12B MYLPF MYLL1 NISCH DOCK1 KRT5 KRT8 KRT1 SRC CSK DESMOSOMES 29 DSP PKP3 JUP PKP4 DSG2 PKP2 DSC2 PKP1 CTNNB1 CTNND1 DSC1 DSC3 DSG1 DSG3 ERBB2 TCF4 ARHGDIA CTNNA1 APC CDH1 CDH2 CDH3 CDH5 VIM KRT18 KRT14 KRT8 KRT5 KRT1 ECM 147 MMP3 MMP1 VEGFA MMP2 MMP9 MMP14 FN1 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 THBS1 LTBP1 ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGA10 ITGA11 ITGAD ITGAE ITGAL ITGAM ITGAX ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 FURIN COL1A2 EMILIN1 MMP13 FGF1 PROK1 FLT1 KDR TGFA TNF LTA FGF2 EGF CD3D FGFR1 EFNA1 EFNB1 EPHA2 IGF1 IGF1R COL4A1 COL2A1 LAMA1 LAMA4 LAMA5 MMP15 MMP16 COL1A1 COL5A1 COL6A3 COL6A2 FBLN2 FBLN1 TIMP2 TIMP3 THBS2 EGFR VTN LAMA2 LAMA3 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 MMP12 ZYX ERBB2 EDNRA EDN1 KITLG KIT MMP10 PLCB1 PLCB2 PLCB3 PLCB4 HBEGF ERBB3 FGFR2 FGFR3 FGFR4 ERBB4 PDGFRA PDGFRB FLT3 FLT4 MET EPHA1 EPHB1 EPHB2 TIMP1 PDGFA PDGFC PDGFD FGF3 FGF4 FGF6 FGF7 FGF8 FGF9 FGF10 FGF16 FGF19 PLCG1 PLCG2 LGALS3 ELN SERPINF2 COL3A1 IGF2 IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 PTP4A3 HGF SMAD2 EMT_REGULATORS 629 SNAI1 SNAI2 ZEB1 ZEB2 TWIST1 MMP3 TWIST2 CTBP1 KAT5 SIRT1 IL2 EP300 TAF5L SMAD3 DR1 CBX4 SRF LMO2 SMAD2 SMAD1 MMP1 VEGFA TCF3 CDH1 CRB3 OCLN CLDN7 F11R TJP3 GJB3 CLDN4 DSP PKP3 CDH2 CDH3 VIM CDH4 MMP2 MMP9 MMP14 FN1 MPP5 BAK1 BBC3 CDC42 CASK LIN7C C16orf70 INADL MPDZ TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGA10 ITGA11 ITGAD ITGAE ITGAL ITGAM ITGAX ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 ACTA1 ACTA2 ACTB ACTC1 ACTG1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 ZFYVE9 FURIN CXADR TJP1 TJP2 CLDN3 CDKN2B SP1 CDK4 CDK6 CCND1 CDKN1B CDKN1A CDKN2A GSK3B CDC25A MYC FOXO1 CCNE1 CDK2 ZBTB17 COL1A2 EMILIN1 MMP13 PARD6A SMURF1 RHOA ETS1 SIX1 E2F1 FGF1 CDKN1C HRAS RAF1 YWHAB MAP2K1 MAP2K2 MAPK3 MAPK1 MKNK1 MKNK2 EIF4E HIF1A KRT14 KRT18 KRT19 ARNT L1CAM PROK1 FLT1 KDR TP53 BAX BCL2L1 BCL2 CDH5 CTNNB1 DNMT1 DPCR1 GPR12 HDAC1 HDAC2 BMI1 CSNK1A1 AXIN1 DVL1 APC LEF1 TCF4 TGFA TNF LTA FGF2 EGF EZH2 PARD3 ROCK1 ROCK2 CFL1 LIMK1 RAC1 PAK1 PAK2 PAK3 WASF1 WASF2 WAS WASL ACTR2 ACTR3 CDC42BPA MAP3K11 PAK4 LIMK2 PRKCZ CDC42EP2 CDC42EP3 CDC42SE1 CYFIP2 BAIAP2 ARFIP2 PIP5K1A MCF2L NCK1 NCKAP1 RALBP1 ABR ARHGAP1 ARHGAP9 ARHGAP12 ARHGAP24 SRGAP3 BCR RACGAP1 ARHGAP32 CHN2 ARHGDIA ARHGDIB CASP1 CASP3 EZR VAV1 VAV2 ARHGEF2 ARHGEF4 LCP2 ZAP70 CD3D CD19 TIAM1 MCF2 ECT2 TNK2 PGGT1B ARHGDIG BNIP2 FGFR1 DLC1 ARHGAP5 RASA1 FYN ARHGAP31 ARHGAP17 FGD1 DOCK6 DOCK9 DOCK11 FGD4 SPATA13 DEF6 ARHGEF3 ARHGEF10L RTKN RHPN2 PKN1 PLCE1 DIAPH1 DIAPH3 RHOB ARHGEF1 PLD1 RAP1GDS1 NGEF EFNA1 EFNB1 EPHA2 IGF1 IGF1R ARHGEF12 PTK6 MYO9B ARHGAP26 CSK JAM2 JAM3 CLDN1 CLDN2 CLDN5 CLDN8 CLDN14 CLDN16 CLDN19 CLDN18 WNK4 MTDH GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJC1 GJD2 JUP PKP4 DSG2 COL4A1 COL2A1 LAMA1 LAMA4 LAMA5 MMP15 MMP16 PKP2 COL1A1 COL5A1 COL6A3 COL6A2 FBLN2 FBLN1 TIMP2 TIMP3 THBS2 MLLT4 CGN MYH1 PVRL1 CAV1 TSPAN3 CLDN11 PRKCA PRKCG PRKCE PRKCB SRC GJB5 CCND3 ARHGAP35 RDX MSN EGFR AKT1 PTEN CCND2 DIAPH2 RHPN1 MAP3K10 MAP3K7 PARD6B PARD6G PIP5K1B PIP5K1C DSTN VTN LAMA2 LAMA3 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 MMP12 PXN VCL TLN1 TLN2 ACTN1 ACTN2 ACTN4 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYH10 MYH11 MYH13 MYH14 MYH15 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL6B MYL7 MYL10 MYL12A MYL12B MYLPF MYLL1 NISCH PTK2 PTK2B ABL1 CRK DOCK1 BCAR1 ZYX DSC2 PKP1 CSNK2A1 PPP1CA PPP1CB PPP1CC FRAT1 CHUK CTNND1 DSC1 DSC3 DSG1 DSG3 ERBB2 CTNNA1 KRT8 KRT5 KRT1 SIN3A MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MAPK10 SOX2 MDM2 ATM COPS2 KLF8 RELA FOXC2 GSC ID1 EDNRA EDN1 ID2 ID3 HMGA2 ATF3 JUNB SHC1 SOS1 SOS2 GRB2 SMURF2 NOTCH1 JAG1 KITLG KIT CTBP2 HDAC3 AKT2 FOXO3 MIB2 NEURL NUMB UBE2D2 UBE2D1 DTX1 PSEN1 DLL1 ADAM17 ADAM10 TCF12 TRAF6 RBPJ NCOR2 NCOR1 CIR1 HEY1 HEY2 RUNX2 MMP10 EZH1 WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16 WNT5A-AS1 FZD1 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAQ GNB1 GNB2 GNB3 GNB4 GNB GNB5 GNG2 GNG GNG4 GNG5 GNG7 GNG8 GNG10 GNG11 GNG12 GNG13 GNGT1 GNG3 LRP5 LRP6 AXIN2 PLCB1 PLCB2 PLCB3 PLCB4 PRKCD PIK3C2A PIK3C2B PIK3C2G PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3C3 PIK3R4 PDPK1 HBEGF ADAM9 ERBB3 FGFR2 FGFR3 FGFR4 ERBB4 PDGFRA PDGFRB FLT3 FLT4 MET EPHA1 EPHB1 EPHB2 JNK1 JNK2 TYK2 STAT1 STAT5A STAT5B STAT3 STAT6 FOS TIMP1 PDGFA PDGFC PDGFD FGF3 FGF4 FGF6 FGF7 FGF8 FGF9 FGF10 FGF16 FGF19 PLCG1 PLCG2 FRS2 LGALS3 ELN SERPINF2 COL3A1 IGF2 IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IRS1 BAD YWHAQ YWHAZ YWHAE SFN YWHAG YWHAH MAP3K5 PTP4A3 HGF MIR106B MIR21 MIR205 MIR192 MIR34A MIR34B MIR34C MIR200A MIR200B MIR200C MIR141 MIR429 MIR1-1 MIR31 MIR449A MIR203 MIR183 MIR30E KLF4 BIRC5 GAP_JUNCTIONS 18 GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJC1 GJD2 PRKCA PRKCG PRKCE PRKCB SRC PRKCZ GJB5 CSK FYN TIGHT_JUNCTIONS 41 OCLN CLDN7 F11R TJP3 CLDN4 MPP5 ACTA1 ACTA2 ACTB ACTC1 ACTG1 CXADR TJP1 TJP2 CLDN3 PARD6A SMURF1 RHOA PARD3 RAC1 RHOB JAM2 JAM3 CLDN1 CLDN2 CLDN5 CLDN8 CLDN14 CLDN16 CLDN19 CLDN18 WNK4 MTDH MLLT4 CGN PVRL1 CAV1 TSPAN3 CLDN11 JUNB SMURF2 HEDGEHOG 281 AKAP1 AKAP2 AKAP3 AKAP4 AKAP5 AKAP6 AKAP7 AKAP8 AKAP9 AKAP10 AKAP12 AKA13 AKAP14 AKAP17A AKT1 AKT2 AKT3 CDH2 SAE1 BOC CDC34 CDON CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 CCNB1 DYNC1H1 DYNC2H1 DYRK1A DYRK1B DYRK2 DYRK3 DYRK4 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z UBE3A UBE3B UBE3C UBE3D GAS1 GAS2 GAS5 GAS6 GAS7 GAS8 GLI1 GLI2 GLI3 GPC1 GPC2 GPC3 GPC4 GPC5 GRK1 GRK4 GRK5 GRK6 GRK7 ADRBK1 ADRBK2 GSK3B GNAI1 GNAI2 GNAI3 GNB1 GNB2 GNB3 GNB4 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG10 GNG11 GNG12 GNG13 HHIP IFT122 IFT140 ITCH KIF3A KIF3B KIF7 MAP3K10 NUMB PIAS1 PRKACA PRKACB PPP2R1A PPP2R1B PPP2R2A PPP2CA PPP2CB PTCH1 PTCH2 RAB23 RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS RBX1 STIL SKP1 SMO SUFU TULP3 UBE21 MSH6 ULK3 WDR19 ARRB1 ARRB2 BTRC FBXW11 RPS6KB2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ CREBBP CREB3 CREB5 CDK8 XPO1 CUL3 CCNC STK36 HAT1 HDAC1 HDAC3 JUN KCTD21 KCTD6 PCBD2 HNF1A HNF1B TCF3 TCF4 CEBPB TCFL5 TFAM TCF7 TCF7L1 TCF7L2 ZEB1 GCFC2 LEF1 NFE2L1 TCF12 TEAD1 TEAD4 HNF4A TCF15 CHUK ZNF354A TCF19 TCF20 TCF21 TCF23 TCF24 TCF25 MED12 MED13 SIN3A MYCN KCTD11 SAP18 SKI SPOP CTNNB1 FES CASP9 FHL2 GNB GNB5 GNG GNGT1 PREX1 PREX2 RAC1 TIAM1 TSC1 TSC2 CARD8 PIK3R5 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 ARC BCL2 CCND1 CCND2 CCND3 TNFRSF10A FOXA2 FOXC2 FOXE1 FOXF1 FOXL1 FOXM1 FOXP3 FOXQ1 HIP1 IGFBP6 IL1R2 JAG2 MIR17HG MIR29B1 MIR29B2 MIR378 MMP11 NKX2-2 PAX6 PAX9 RUNX2 S100A7 S100A9 SFRP1 SIX1 SNAI1 TBX2 ULK1 WNT11 BAK1 BCL2L11 BMF CTGF E2F1 ESR1 FUS HRK PTEN BBC3 STAT3 TNF THBS1 MAPK 208 AKT1 AKT2 AKT3 CDH2 GRK1 GRK4 GRK5 GRK6 GRK7 ADRBK1 ADRBK2 GSK3B PPP2CA PPP2CB RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS ARRB1 ARRB2 JUN PCBD2 HNF1A HNF1B TCF3 TCF4 CEBPB TCFL5 TFAM TCF7 TCF7L1 TCF7L2 ZEB1 GCFC2 LEF1 NFE2L1 TCF12 TEAD1 TEAD4 HNF4A TCF15 CHUK ZNF354A TCF19 TCF20 TCF21 TCF23 TCF24 TCF25 CTNNB1 CASP9 RAC1 PIK3CA PIK3CB PIK3CD PIK3CG ATF2 ATM BAD BCL2 BRAF CREB1 CASP3 CASPASE3 DDIT3 DUSP1 DUSP5 DUSP6 ELK1 MAPK1 MAPK3 MAPK4 MAPK6 ERN1 FOS FOXO3 FRS2 GAB1 GADD45A GADD45B GPR1 GPR3 GPR4 GPR6 GPR12 GPR15 GPR17 GPR18 GPR19 GPR20 GRB2 HSPB1 IL1R1 BRAP IRAK1 MAPK8 MAPK9 MAPK10 KSR1 LAMTOR2 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K1 MAP3K10 MAP3K11 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAPKAPK2 MAPKAPK3 MAPKAPK5 MAX MDM2 MAP2K1 MAP2K2 MKNK1 MKNK2 LAMTOR3 RPS6KA4 RPS6KA5 MST1 MYC MYD88 NFATC1 NFATC3 NFATC2 NFATC4 NFAT5 PRKCA PRKCB PRKCG PRKCD PRKCE PRKCH PRKCI PRKCQ PKD1 PLA2G4A PLCG1 PPID RAF1 RASGRP1 RIPK1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 PIM1 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN IL17RD SMAD2 SMAD3 SMAD4 SOS1 SOS2 SPRY1 SPRY2 SRC STAT1 SHOC2 TAB1 TAB2 TAB3 MAP3K7 TAOK1 TAOK2 TAOK3 TGFBR1 TGFBR2 TNFRSF1A TNFRSF1B TRADD TRAF2 TRAF6 TXN CDKN2A CDKN1A MAPK11 MAPK12 MAPK13 MAPK14 TP53 RPS6KB1 DDB2 EGR1 GADD45G MMP13 PERP PMAIP1 PI3K_AKT_MTOR 296 AKT1 AKT2 AKT3 CDH2 CDC34 CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z UBE3A UBE3B UBE3C UBE3D GSK3B PPP2R1A PPP2R1B PPP2R2A PPP2CA PPP2CB RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS RBX1 SKP1 BTRC FBXW11 RPS6KB2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ CREBBP CREB3 CREB5 XPO1 DYRK1A CASP9 RAC1 TSC1 TSC2 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 BAD CASP3 FOXO3 GAB1 GRB2 MDM2 PRKCA PRKCB PRKCG PRKCD PRKCE PRKCH PRKCI PRKCQ RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN SOS1 SOS2 CDKN1A TP53 RPS6KB1 EIF4EBP1 APAF1 ATG13 BAX BCL2L1 CBL CBLB CBLC CDK1 CDK4 CDK6 CSNK2A1 CSNK2A2 CSNK2B CUL4A CUL4B CYCS CASP8 CCND1 CCND2 CCND3 DCAF4 DCAF5 DCAF6 DCAF7 DCAF8 DCAF10 DCAF11 DCAF12 DCAF13 DCAF15 DCAF16 DCAF17 DEK DEPTOR EIF3A EIF3B EIF3C EIF3D EIF3E EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF4A1 EIF4A2 EIF4A3 EIF4B EIF4E EIF4E1B EIF4E2 EIF4E3 EIF4G1 EIF4G2 EIF4G3 NOS3 FBXW5 FBXW7 RB1CC1 FRK HERC1 HSP90AA1 HSP90AA2 HSP90AB1 HSP90B1 IKBKB MAPKAP1 MLST8 MTOR NEDD4 PABPC1 PABPC3 PABP5 MYCBP2 PDCD4 PDPK1 PHLPP1 PHLPP2 PPP3R1 PPP3R2 PPP3CA PPP3CB PPP3CC AKT1S1 PRR5 PTEN ALYREF RHEB RICTOR RNPS1 RPS6 RPTOR SGK1 INPP5D POLDIP3 SRRM1 SDC4 ULK1 ULK2 RBM8A CDKN1B BCOR RNF7 CDK2 DTL CKS1B CREB1 CCNE1 CCNE2 DAXX DYRK1B E2F1 FOXO1 FOXO4 USP7 CHUK IKBKE IKBKG IPO4 IPO5 IPO7 IPO8 IPO9 IPO11 IPO13 UHMK1 RNF123 UBAC1 PCNA RCHY1 PML PPP2R2B PPP2R2C PPP2R2D PPP2R3A PPP2R3B PPP2R3C PPP2R4 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RUNX2 SKP2 BCL2 GADD45A GADD45B GADD45G BCL6 BCL2L11 FASLG MCL1 PINK1 PLK1 PLK2 PLK3 PLK4 BBC3 RAD51 TRADD TNFSF10 CDKN2B CDKN2D WNT_CANONICAL 431 CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 DYNC2H1 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 GSK3B KIF3A KIF3B PIAS1 PPP2CA PPP2CB RBX1 ARRB1 ARRB2 BTRC FBXW11 CREBBP CREB3 CREB5 XPO1 CUL3 JUN PCBD2 HNF1A HNF1B TCF3 TCF4 CEBPB TCFL5 TFAM TCF7 TCF7L1 TCF7L2 ZEB1 GCFC2 LEF1 NFE2L1 TCF12 TEAD1 TEAD4 HNF4A TCF15 CHUK ZNF354A TCF19 TCF20 TCF21 TCF23 TCF24 TCF25 CTNNB1 GNB1 GNB2 GNB3 GNB4 GNB GNB5 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG10 GNG11 GNG12 GNG13 GNG GNGT1 SMAD2 SRC MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 TP53 E2F1 TPBG FAM123B APC ATP6V0C ATP6V0D1 ATP6VOC ATP6V0D2 AXIN1 AXIN2 CSNK2A2 CSNK2A3 CSNK2A1 CSNK2B CSKN2B GPS1 GPS2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CCNY DAB1 DAB2 DVL1 DVL2 DVL3 CDH1 FAF1 FAF2 FZD1 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GSK3A GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAQ CXXC4 INVS AHI1 KLHL1 KLHL2 KLHL3 KLHL4 KLHL5 KLHL6 KLHL7 KLHL8 KLHL9 KLHL10 KLHL11 KLHL12 KLHL13 KLHL14 KLHL15 KLHL17 KLHL18 KLHL20 KLHL21 KLHL22 KLHL23 KLHL24 KLHL25 KLHL26 KLHL28 KLHL29 KLHL30 KLHL31 KLHL32 KLHL33 KLHL34 KLHL35 KLHL36 KLHL38 LRP5 LRP6 MARK2 NEDD8 HECW1 HECW2 CDK14 PI4K2A PI4K2B PIP5K1A PIP5K1B PIP5K1C PRKD1 PRKD2 PRKD3 PPP1CA PPP1CB PPP1CC PPP1R1A PPP1R1B PPP1R1C PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3E PPP1R3F PPP1R3G PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R14C PPP1R14D PPP1R15A PPP1R15B PPP1R16A PPP1R16B PPP1R17 PPP1R18 PPP1R21 PPP1R26 PPP1R27 PPP1R32 PPP1R35 PPP1R36 PPP1R37 PPP1R39 PPP1R42 PPP2R2A PPP2R1A ATP6AP2 ATP6AP1 UBE2A UBE2B RGS19 SKP1 SKP2 USP15 WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16 WNT5A-AS1 CTNND1 CTNND2 TDGF1 DKK1 DKK3 HECTD1 ITGA3 ITGA9 KREMEN1 KREMEN2 NKD1 RIPK4 RNF146 RSPO1 TGFB1 TGFBR1 TGFBR2 TGFBR3 TMEM198 TNKS TNKS2 USP8 XFZ3 XFZ7 CTNNA1 CTNNA2 CTNNA3 EP400 EP300 ACTB VPS72 XIAP WDR5 USP34 UBE2C TRRAP TLE1 TLE2 TLE3 TLE4 AES TLE6 TAB2 TAB1 SOX9 SMAD1 SIX3 RUVBL2 POLR2B ROR2 RELA RBBP5 RBBP4 RBBP7 RUVBL1 PYGO1 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKAA1 PRKAA2 PRKACA PRKACB PRKACG KAT2B NLK NOTCH1 NOTCH2 NOTCH3 NOTCH4 NFKB1 NDUFA6 NARF MEN1 MTA1 MTA2 MTA3 MRGBP MORF4L1 MLL2 MBD2 MBD3 KLF8 KLF4 IRS2 ING3 HIPK2 HIPK1 HES1 HDAC1 HDAC2 HCFC2 HIST2H2BE H2AFZ H2AFX GATAD2A GATADB YEATS4 EPC1 MEAF6 DPY30 DMAP1 DACT1 CTBP1 CTBP2 CHD3 CHD4 CDC20 SMARCA4 BRD8 BRD7 BCL9 SMARCD1 SMARCE1 ACTL6A SMARCB1 PHF10 ARID1A PBRM1 SMARCC1 BANF1 PPP2R5A ACTA1 ACTG1 ASH2L CDC23 ANAPC7 CDC16 ANAPC5 ANAPC4 CDC27 ANAPC2 ANAPC13 CDC26 ANAPC11 ANAPC10 ANAPC1 FERMT2 MSI1 SIRT1 SIRT2 CCND1 CCND2 CCND3 MYC MIR34A MIR34B MIR34C MIR372 MIR373 MMP9 NOS2 MIR23B FTX MIR375 WIF1 MIR204 MIR31 MIR493 WNT_NON_CANONICAL 425 AKT1 AKT2 AKT3 CDH2 CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 DYRK1A DYRK1B DYRK2 DYRK3 DYRK4 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z PIAS1 PPP2R1A PPP2R1B RBX1 SKP1 UBE21 MSH6 ARRB1 ARRB2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ XPO1 JUN CTNNB1 GNB1 GNB2 GNB3 GNB4 GNB GNB5 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG10 GNG11 GNG12 GNG13 GNG GNGT1 RAC1 PIK3R5 PIK3CB PIK3CG BAD CASPASE3 CASP3 MAPK1 MAPK3 MAPK4 MAPK6 FOS MAPK8 MAPK9 MAPK10 MDM2 MYC NFATC1 NFATC3 NFATC2 NFATC4 NFAT5 PRKCA PRKCB PRKCG PRKCD PRKCE PRKCH PRKCI PRKCQ RAF1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 TP53 BAX BCL2L1 CASP8 PTEN SDC4 DAXX FOXO1 PML PPP2R2A PPP2R2B PPP2R2C PPP2R2D PPP2R3A PPP2R3B PPP2R3C PPP2R4 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E APC ATP6V0C ATP6V0D1 ATP6VOC ATP6V0D2 AXIN1 AXIN2 CSNK2A2 CSNK2A3 CSNK2A1 CSNK2B CSKN2B DVL1 DVL2 DVL3 CDH1 FZD1 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GSK3A GSK3B LRP5 LRP6 ATP6AP2 ATP6AP1 WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16 WNT5A-AS1 CTNND1 CTNND2 CTNNA1 CTNNA2 CTNNA3 TAB2 TAB1 ROR2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKAA1 PRKAA2 PRKACA PRKACB PRKACG HIPK2 DACT1 ANAPC2 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY10 CAMK2A CAMK2B CAMK2D CAMK2G CTGF CTHRC1 CALM1 CALM2 CALM3 CAPN1 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 SOLH CAPNS1 CAPNS2 DAAM1 GNA11 GNA12 GNA13 GNA14 GNA15 GNAS HBEGF ITPR1 ITPR2 ITPR3 JUNB JUND LGR5 MINK1 MMP1 F2R PARD6A PIP5KIC PIP5K1C PLCB1 PLCB2 PLCB3 PLCB4 SH3RF1 PRICKLE1 PTH1R PTH26 GNB2L1 RGS3 RHOA ROCK1 ROCK2 RSPO1 RSPO2 RSPO3 RSPO4 SEC24B SMURF1 ADAM17 F2 VANGL2 VANGL1 ARHGEF19 MAP3K5 FBXO32 BID CABIN1 CASR CSE1L CAST HOMER3 IQGAP1 IQGAP2 IQGAP3 KPNB1 LRRK2 MEF2A MEF2B MEF2C MEF2D PPP3CB PPP3R1 PPP3PR2 PPP3R2 RCAN1 RCAN2 RCAN3 TNPO1 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 PPP3CA PPP3CC ESR1 ESR2 FOXA1 FOXA2 FOXA3 GATA1 GATA2 GATA3 GATA4 GATA5 GATA6 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC10 HDAC11 MAP2K1 PARP1 PARP2 PARP3 PARP4 PARP6 TIPARP PARP8 PARP9 PARP10 PARP11 PARP12 PARP14 PARP15 PARP16 TGFB1 TGFB2 TGFB3 AMER2 ACTA1 ACTB ACTG1 DLG1 DLG2 DLG3 DLG4 DLG5 MAPRE1 MAPRE2 MAPRE3 FGF2 HUWE1 HRAS HSPA8 HSPA1A HSPA1B DNAJA3 MAP2K2 PIN1 PPP2CA PPP2CB SNAI1 EREG IL2 CDK4 GPC6