site	wildtype	mutation	Type	toAA	min Subst	accessibility
9	D	N	Known human adaptive	N	0.9987429289754871	1
74	G	S	Known human adaptive	S	1.5556253928346953	>1
158	E	G	Known human adaptive	G	0.9993714644877436	1
189	K	R	Known human adaptive	R	1.0	1
192	E	K	Known human adaptive	K	1.0	1
199	A	S	Known human adaptive	S	0.9962287869264613	1
253	D	N	Known human adaptive	N	1.0	1
256	D	G	Known human adaptive	G	1.0006285355122564	1
271	T	A	Known human adaptive	A	1.0031426775612822	1
286	S	G	Known human adaptive	G	0.9987429289754871	1
489	S	P	Known human adaptive	P	1.0	1
526	K	R	Known human adaptive	R	0.9597737272155877	1
534	S	F	Known human adaptive	F	1.6580766813324952	>1
535	M	T	Known human adaptive	T	1.0446260213702074	1
588	A	I	Known human adaptive	I	1.8177247014456317	>1
591	Q	K	Known human adaptive	K	1.0050282840980516	1
598	T	T	Known human adaptive	T	0.1816467630421119	1
627	E	K	Known human adaptive	K	0.9924575738529227	1
636	L	F	Known human adaptive	F	1.8755499685732244	>1
660	K	R	Known human adaptive	R	0.9736015084852294	1
684	A	S	Known human adaptive	S	0.9874292897548711	1
701	D	N	Known human adaptive	N	0.9987429289754871	1
701	D	V	Known human adaptive	V	1.0012570710245128	1
702	K	R	Known human adaptive	R	0.896291640477687	1
714	S	R	Known human adaptive	R	1.0	1
740	D	N	Known human adaptive	N	0.9987429289754871	1
9	D	K	Top adaptive in A549	K	1.9962287869264614	>1
69	E	R	Top adaptive in A549	R	1.9987429289754872	>1
69	E	K	Top adaptive in A549	K	1.0006285355122564	1
82	N	W	Top adaptive in A549	W	2.9880578252671275	>1
156	A	M	Top adaptive in A549	M	2.9208045254556882	>1
158	E	L	Top adaptive in A549	L	2.0	>1
163	I	C	Top adaptive in A549	C	2.1257071024512886	>1
169	P	E	Top adaptive in A549	E	2.0	>1
176	I	E	Top adaptive in A549	E	2.0087994971715903	>1
182	Q	Y	Top adaptive in A549	Y	2.0	>1
182	Q	N	Top adaptive in A549	N	2.0	>1
183	L	D	Top adaptive in A549	D	2.9993714644877434	>1
183	L	N	Top adaptive in A549	N	2.912005028284098	>1
190	K	Y	Top adaptive in A549	Y	2.006913890634821	>1
292	I	T	Top adaptive in A549	T	1.0634820867379007	1
355	R	G	Top adaptive in A549	G	1.0307982401005658	1
521	T	F	Top adaptive in A549	F	2.923318667504714	>1
521	T	W	Top adaptive in A549	W	2.974230043997486	>1
521	T	Q	Top adaptive in A549	Q	2.0703959773727214	>1
521	T	L	Top adaptive in A549	L	2.0	>1
521	T	I	Top adaptive in A549	I	1.032683846637335	1
521	T	Y	Top adaptive in A549	Y	2.9170333123821495	>1
521	T	V	Top adaptive in A549	V	1.993086109365179	>1
522	Q	I	Top adaptive in A549	I	2.427404148334381	>1
532	S	D	Top adaptive in A549	D	2.995600251414205	>1
627	E	C	Top adaptive in A549	C	3.0	>1
627	E	S	Top adaptive in A549	S	2.0	>1
669	G	S	Top adaptive in A549	S	1.9968573224387178	>1
676	T	Y	Top adaptive in A549	Y	2.509742300439975	>1
684	A	K	Top adaptive in A549	K	2.454431175361408	>1
698	G	K	Top adaptive in A549	K	2.9849151477058453	>1
701	D	N	Top adaptive in A549	N	0.9987429289754871	1
701	D	M	Top adaptive in A549	M	2.998742928975487	>1
701	D	C	Top adaptive in A549	C	2.0	>1
1	M	A	All mutations	A	2.0	>1
1	M	W	All mutations	W	2.0	>1
1	M	D	All mutations	D	3.0	>1
1	M	V	All mutations	V	1.0	1
1	M	E	All mutations	E	2.0	>1
1	M	T	All mutations	T	1.0	1
1	M	F	All mutations	F	2.0	>1
1	M	S	All mutations	S	2.0	>1
1	M	C	All mutations	C	3.0	>1
1	M	R	All mutations	R	1.0	1
1	M	Q	All mutations	Q	2.0	>1
1	M	H	All mutations	H	3.0	>1
1	M	P	All mutations	P	2.0	>1
1	M	I	All mutations	I	1.0	1
1	M	N	All mutations	N	2.0	>1
1	M	K	All mutations	K	1.0	1
1	M	M	All mutations	M	0.0	0
1	M	G	All mutations	G	2.0	>1
1	M	Y	All mutations	Y	3.0	>1
1	M	L	All mutations	L	1.0	1
2	E	H	All mutations	H	1.9214330609679446	>1
2	E	L	All mutations	L	1.9993714644877436	>1
2	E	Y	All mutations	Y	1.9208045254556882	>1
2	E	S	All mutations	S	1.9245757385292268	>1
2	E	C	All mutations	C	2.9195474544311755	>1
2	E	D	All mutations	D	0.9968573224387178	1
2	E	R	All mutations	R	1.9993714644877436	>1
2	E	T	All mutations	T	1.9252042740414834	>1
2	E	P	All mutations	P	2.0	>1
2	E	W	All mutations	W	2.2759270898805783	>1
2	E	M	All mutations	M	2.2023884349465743	>1
2	E	A	All mutations	A	1.0754242614707732	1
2	E	V	All mutations	V	1.0754242614707732	1
2	E	E	All mutations	E	0.1552482715273413	1
2	E	Q	All mutations	Q	1.0798240100565681	1
2	E	K	All mutations	K	1.0050282840980516	1
2	E	I	All mutations	I	2.648020113136392	>1
2	E	N	All mutations	N	1.846637335009428	>1
2	E	G	All mutations	G	1.0747957259585166	1
2	E	F	All mutations	F	2.9201759899434316	>1
3	R	P	All mutations	P	1.9333752357008172	>1
3	R	Q	All mutations	Q	1.9327467001885608	>1
3	R	S	All mutations	S	1.0672532998114392	1
3	R	M	All mutations	M	2.0659962287869265	>1
3	R	N	All mutations	N	2.0659962287869265	>1
3	R	F	All mutations	F	3.0	>1
3	R	I	All mutations	I	1.0672532998114392	1
3	R	T	All mutations	T	1.0666247642991828	1
3	R	D	All mutations	D	2.9993714644877434	>1
3	R	K	All mutations	K	1.0659962287869265	1
3	R	E	All mutations	E	1.9993714644877436	>1
3	R	G	All mutations	G	1.0006285355122564	1
3	R	V	All mutations	V	2.0	>1
3	R	R	All mutations	R	0.0006285355122564425	1
3	R	C	All mutations	C	2.0006285355122566	>1
3	R	L	All mutations	L	1.9333752357008172	>1
3	R	A	All mutations	A	2.0	>1
3	R	W	All mutations	W	2.0	>1
3	R	H	All mutations	H	2.9327467001885608	>1
3	R	Y	All mutations	Y	2.9993714644877434	>1
4	I	R	All mutations	R	1.0006285355122564	1
4	I	D	All mutations	D	2.9981143934632306	>1
4	I	Q	All mutations	Q	2.0	>1
4	I	C	All mutations	C	2.9993714644877434	>1
4	I	W	All mutations	W	3.0	>1
4	I	G	All mutations	G	1.9993714644877436	>1
4	I	P	All mutations	P	2.0	>1
4	I	A	All mutations	A	1.9993714644877436	>1
4	I	K	All mutations	K	1.0006285355122564	1
4	I	S	All mutations	S	2.0	>1
4	I	H	All mutations	H	2.998742928975487	>1
4	I	L	All mutations	L	1.0006285355122564	1
4	I	Y	All mutations	Y	2.998742928975487	>1
4	I	F	All mutations	F	2.0	>1
4	I	V	All mutations	V	1.0	1
4	I	T	All mutations	T	1.0006285355122564	1
4	I	I	All mutations	I	0.001257071024512885	1
4	I	E	All mutations	E	1.9993714644877436	>1
4	I	M	All mutations	M	1.0012570710245128	1
4	I	N	All mutations	N	1.9993714644877436	>1
5	K	T	All mutations	T	1.0037712130735386	1
5	K	E	All mutations	E	1.0087994971715901	1
5	K	K	All mutations	K	0.01508485229415462	1
5	K	R	All mutations	R	0.9918290383406663	1
5	K	C	All mutations	C	2.9893148962916403	>1
5	K	Y	All mutations	Y	2.011313639220616	>1
5	K	W	All mutations	W	2.9585166561910747	>1
5	K	L	All mutations	L	1.9981143934632306	>1
5	K	G	All mutations	G	1.9868007542426147	>1
5	K	V	All mutations	V	1.9968573224387178	>1
5	K	H	All mutations	H	2.010056568196103	>1
5	K	D	All mutations	D	2.0087994971715903	>1
5	K	M	All mutations	M	1.9723444374607166	>1
5	K	Q	All mutations	Q	1.0100565681961031	1
5	K	P	All mutations	P	1.9987429289754872	>1
5	K	A	All mutations	A	1.9974858579509742	>1
5	K	N	All mutations	N	1.0150848522941547	1
5	K	I	All mutations	I	1.033940917661848	1
5	K	F	All mutations	F	2.9993714644877434	>1
5	K	S	All mutations	S	1.9893148962916405	>1
6	E	I	All mutations	I	2.0125707102451287	>1
6	E	E	All mutations	E	0.0031426775612822125	1
6	E	G	All mutations	G	1.0006285355122564	1
6	E	S	All mutations	S	1.9993714644877436	>1
6	E	T	All mutations	T	1.9981143934632306	>1
6	E	V	All mutations	V	1.0012570710245128	1
6	E	F	All mutations	F	2.9993714644877434	>1
6	E	R	All mutations	R	1.9981143934632306	>1
6	E	N	All mutations	N	1.9993714644877436	>1
6	E	W	All mutations	W	2.985543683218102	>1
6	E	P	All mutations	P	1.9993714644877436	>1
6	E	L	All mutations	L	2.0	>1
6	E	D	All mutations	D	1.0018856065367694	1
6	E	M	All mutations	M	2.9849151477058453	>1
6	E	K	All mutations	K	1.0006285355122564	1
6	E	A	All mutations	A	1.0006285355122564	1
6	E	H	All mutations	H	2.0006285355122566	>1
6	E	Y	All mutations	Y	2.0006285355122566	>1
6	E	Q	All mutations	Q	1.0018856065367694	1
6	E	C	All mutations	C	2.998742928975487	>1
7	L	I	All mutations	I	1.0515399120050284	1
7	L	L	All mutations	L	0.0	0
7	L	R	All mutations	R	1.1018227529855438	>1
7	L	C	All mutations	C	2.881835323695789	>1
7	L	Y	All mutations	Y	2.881835323695789	>1
7	L	W	All mutations	W	2.846637335009428	>1
7	L	M	All mutations	M	1.9484600879949716	>1
7	L	D	All mutations	D	2.9836580766813325	>1
7	L	N	All mutations	N	2.9836580766813325	>1
7	L	G	All mutations	G	2.0	>1
7	L	F	All mutations	F	1.8818353236957888	>1
7	L	P	All mutations	P	1.1018227529855438	>1
7	L	V	All mutations	V	1.0	1
7	L	E	All mutations	E	2.0163419233186675	>1
7	L	K	All mutations	K	2.0163419233186675	>1
7	L	Q	All mutations	Q	1.1181646763042112	>1
7	L	H	All mutations	H	2.085480829666876	>1
7	L	A	All mutations	A	2.0	>1
7	L	S	All mutations	S	1.8981772470144562	>1
7	L	T	All mutations	T	2.0	>1
8	R	F	All mutations	F	3.0	>1
8	R	H	All mutations	H	2.9905719673161535	>1
8	R	A	All mutations	A	2.0	>1
8	R	Y	All mutations	Y	2.9974858579509744	>1
8	R	I	All mutations	I	1.0175989943431805	1
8	R	S	All mutations	S	1.0094280326838467	1
8	R	E	All mutations	E	1.9974858579509742	>1
8	R	D	All mutations	D	2.9974858579509744	>1
8	R	N	All mutations	N	2.004399748585795	>1
8	R	Q	All mutations	Q	1.9905719673161533	>1
8	R	P	All mutations	P	1.993086109365179	>1
8	R	W	All mutations	W	1.9918290383406663	>1
8	R	L	All mutations	L	1.993086109365179	>1
8	R	K	All mutations	K	1.0043997485857952	1
8	R	M	All mutations	M	1.9962287869264614	>1
8	R	G	All mutations	G	1.0025141420490258	1
8	R	C	All mutations	C	2.0025141420490256	>1
8	R	R	All mutations	R	0.00251414204902577	1
8	R	T	All mutations	T	1.006913890634821	1
8	R	V	All mutations	V	2.0	>1
9	D	E	All mutations	E	1.011313639220616	1
9	D	D	All mutations	D	0.013827781269641735	1
9	D	Q	All mutations	Q	2.003142677561282	>1
9	D	K	All mutations	K	1.9962287869264614	>1
9	D	S	All mutations	S	1.9880578252671275	>1
9	D	V	All mutations	V	1.0075424261470773	1
9	D	A	All mutations	A	1.0081709616593337	1
9	D	P	All mutations	P	2.0	>1
9	D	W	All mutations	W	2.994343180389692	>1
9	D	N	All mutations	N	0.9987429289754871	1
9	D	I	All mutations	I	1.993086109365179	>1
9	D	F	All mutations	F	1.9993714644877436	>1
9	D	L	All mutations	L	1.9993714644877436	>1
9	D	M	All mutations	M	2.9918290383406663	>1
9	D	H	All mutations	H	1.005656819610308	1
9	D	T	All mutations	T	1.993086109365179	>1
9	D	R	All mutations	R	1.9962287869264614	>1
9	D	C	All mutations	C	1.9962287869264614	>1
9	D	G	All mutations	G	1.0043997485857952	1
9	D	Y	All mutations	Y	1.0043997485857952	1
10	L	A	All mutations	A	1.9993714644877436	>1
10	L	T	All mutations	T	2.0	>1
10	L	P	All mutations	P	1.272784412319296	>1
10	L	S	All mutations	S	1.7278441231929604	>1
10	L	G	All mutations	G	1.9993714644877436	>1
10	L	K	All mutations	K	2.001257071024513	>1
10	L	H	All mutations	H	2.271527341294783	>1
10	L	N	All mutations	N	2.998742928975487	>1
10	L	M	All mutations	M	1.7335009428032684	>1
10	L	L	All mutations	L	0.0006285355122564425	1
10	L	Q	All mutations	Q	1.274041483343809	>1
10	L	V	All mutations	V	0.9993714644877436	1
10	L	I	All mutations	I	1.2664990571967316	>1
10	L	F	All mutations	F	1.7265870521684474	>1
10	L	C	All mutations	C	2.7265870521684477	>1
10	L	E	All mutations	E	2.0006285355122566	>1
10	L	R	All mutations	R	1.272784412319296	>1
10	L	W	All mutations	W	2.4613450659962286	>1
10	L	Y	All mutations	Y	2.7265870521684477	>1
10	L	D	All mutations	D	2.9981143934632306	>1
11	M	D	All mutations	D	2.9993714644877434	>1
11	M	G	All mutations	G	1.9993714644877436	>1
11	M	A	All mutations	A	1.9993714644877436	>1
11	M	H	All mutations	H	3.0	>1
11	M	M	All mutations	M	0.00251414204902577	1
11	M	K	All mutations	K	1.0006285355122564	1
11	M	F	All mutations	F	2.0	>1
11	M	T	All mutations	T	1.0006285355122564	1
11	M	Q	All mutations	Q	2.0	>1
11	M	S	All mutations	S	2.0	>1
11	M	E	All mutations	E	1.9993714644877436	>1
11	M	Y	All mutations	Y	3.0	>1
11	M	R	All mutations	R	1.0006285355122564	1
11	M	C	All mutations	C	3.0	>1
11	M	L	All mutations	L	1.0	1
11	M	W	All mutations	W	2.0018856065367694	>1
11	M	V	All mutations	V	0.9993714644877436	1
11	M	N	All mutations	N	2.0006285355122566	>1
11	M	P	All mutations	P	2.0	>1
11	M	I	All mutations	I	0.9987429289754871	1
12	S	F	All mutations	F	1.9032055311125078	>1
12	S	M	All mutations	M	2.8522941546197362	>1
12	S	A	All mutations	A	1.0037712130735386	1
12	S	T	All mutations	T	1.0037712130735386	1
12	S	L	All mutations	L	1.0892520427404149	1
12	S	H	All mutations	H	2.9069767441860463	>1
12	S	V	All mutations	V	1.9962287869264614	>1
12	S	W	All mutations	W	1.8560653676932746	>1
12	S	I	All mutations	I	2.1401634192331866	>1
12	S	E	All mutations	E	2.0930232558139537	>1
12	S	C	All mutations	C	1.9069767441860466	>1
12	S	P	All mutations	P	1.0037712130735386	1
12	S	Q	All mutations	Q	2.0930232558139537	>1
12	S	G	All mutations	G	2.0	>1
12	S	S	All mutations	S	0.003771213073538655	1
12	S	D	All mutations	D	2.9069767441860463	>1
12	S	N	All mutations	N	2.9069767441860463	>1
12	S	R	All mutations	R	2.0	>1
12	S	K	All mutations	K	2.0930232558139537	>1
12	S	Y	All mutations	Y	1.9069767441860466	>1
13	Q	A	All mutations	A	2.0	>1
13	Q	M	All mutations	M	2.1684475172847266	>1
13	Q	S	All mutations	S	2.0	>1
13	Q	K	All mutations	K	1.0043997485857952	1
13	Q	T	All mutations	T	2.0	>1
13	Q	F	All mutations	F	2.996857322438718	>1
13	Q	L	All mutations	L	0.9993714644877436	1
13	Q	V	All mutations	V	1.9993714644877436	>1
13	Q	Y	All mutations	Y	1.9993714644877436	>1
13	Q	N	All mutations	N	1.9993714644877436	>1
13	Q	I	All mutations	I	2.8302954116907606	>1
13	Q	H	All mutations	H	0.9993714644877436	1
13	Q	G	All mutations	G	1.9987429289754872	>1
13	Q	R	All mutations	R	0.9987429289754871	1
13	Q	W	All mutations	W	2.16781898177247	>1
13	Q	P	All mutations	P	1.0	1
13	Q	Q	All mutations	Q	0.0043997485857950975	1
13	Q	D	All mutations	D	1.9993714644877436	>1
13	Q	E	All mutations	E	1.0043997485857952	1
13	Q	C	All mutations	C	2.996228786926461	>1
14	S	R	All mutations	R	2.0	>1
14	S	P	All mutations	P	1.0006285355122564	1
14	S	W	All mutations	W	2.0	>1
14	S	G	All mutations	G	2.0	>1
14	S	C	All mutations	C	1.0	1
14	S	V	All mutations	V	1.9993714644877436	>1
14	S	A	All mutations	A	1.0006285355122564	1
14	S	H	All mutations	H	2.0	>1
14	S	Q	All mutations	Q	3.0	>1
14	S	M	All mutations	M	2.9993714644877434	>1
14	S	I	All mutations	I	1.9993714644877436	>1
14	S	D	All mutations	D	2.0	>1
14	S	S	All mutations	S	0.0006285355122564425	1
14	S	Y	All mutations	Y	1.0	1
14	S	L	All mutations	L	1.9993714644877436	>1
14	S	F	All mutations	F	0.9993714644877436	1
14	S	E	All mutations	E	3.0	>1
14	S	N	All mutations	N	2.0	>1
14	S	K	All mutations	K	3.0	>1
14	S	T	All mutations	T	1.0006285355122564	1
15	R	C	All mutations	C	1.0	1
15	R	N	All mutations	N	2.0	>1
15	R	Y	All mutations	Y	2.0	>1
15	R	G	All mutations	G	1.0	1
15	R	W	All mutations	W	2.0	>1
15	R	A	All mutations	A	2.0	>1
15	R	T	All mutations	T	2.0	>1
15	R	L	All mutations	L	1.0	1
15	R	P	All mutations	P	1.0	1
15	R	K	All mutations	K	3.0	>1
15	R	E	All mutations	E	3.0	>1
15	R	F	All mutations	F	2.0	>1
15	R	V	All mutations	V	2.0	>1
15	R	S	All mutations	S	1.0	1
15	R	M	All mutations	M	3.0	>1
15	R	D	All mutations	D	2.0	>1
15	R	H	All mutations	H	1.0	1
15	R	Q	All mutations	Q	2.0	>1
15	R	I	All mutations	I	2.0	>1
15	R	R	All mutations	R	0.0	0
16	T	I	All mutations	I	1.0031426775612822	1
16	T	A	All mutations	A	1.0	1
16	T	Y	All mutations	Y	2.0006285355122566	>1
16	T	E	All mutations	E	2.9993714644877434	>1
16	T	W	All mutations	W	3.0	>1
16	T	V	All mutations	V	2.0	>1
16	T	L	All mutations	L	1.9968573224387178	>1
16	T	R	All mutations	R	1.9962287869264614	>1
16	T	T	All mutations	T	0.0031426775612822125	1
16	T	N	All mutations	N	1.0037712130735386	1
16	T	M	All mutations	M	2.003142677561282	>1
16	T	F	All mutations	F	2.0006285355122566	>1
16	T	D	All mutations	D	2.0006285355122566	>1
16	T	Q	All mutations	Q	2.996228786926461	>1
16	T	S	All mutations	S	1.0	1
16	T	G	All mutations	G	2.0	>1
16	T	P	All mutations	P	0.9968573224387178	1
16	T	H	All mutations	H	1.9974858579509742	>1
16	T	C	All mutations	C	2.0006285355122566	>1
16	T	K	All mutations	K	2.0025141420490256	>1
17	R	K	All mutations	K	2.9981143934632306	>1
17	R	T	All mutations	T	2.0	>1
17	R	L	All mutations	L	1.0	1
17	R	M	All mutations	M	3.0	>1
17	R	C	All mutations	C	1.0018856065367694	1
17	R	R	All mutations	R	0.0018856065367693275	1
17	R	V	All mutations	V	2.0	>1
17	R	E	All mutations	E	2.9981143934632306	>1
17	R	P	All mutations	P	1.0	1
17	R	Q	All mutations	Q	1.9981143934632306	>1
17	R	F	All mutations	F	2.0	>1
17	R	N	All mutations	N	1.9981143934632306	>1
17	R	H	All mutations	H	0.9981143934632307	1
17	R	I	All mutations	I	2.0	>1
17	R	G	All mutations	G	1.0018856065367694	1
17	R	A	All mutations	A	2.0	>1
17	R	Y	All mutations	Y	1.9981143934632306	>1
17	R	W	All mutations	W	2.0018856065367694	>1
17	R	S	All mutations	S	1.0018856065367694	1
17	R	D	All mutations	D	1.9981143934632306	>1
18	E	G	All mutations	G	1.0	1
18	E	C	All mutations	C	2.9993714644877434	>1
18	E	E	All mutations	E	0.0006285355122564425	1
18	E	V	All mutations	V	1.0	1
18	E	A	All mutations	A	1.0	1
18	E	T	All mutations	T	2.0	>1
18	E	K	All mutations	K	1.0006285355122564	1
18	E	P	All mutations	P	2.0	>1
18	E	F	All mutations	F	2.9993714644877434	>1
18	E	D	All mutations	D	0.9993714644877436	1
18	E	Q	All mutations	Q	1.0006285355122564	1
18	E	N	All mutations	N	1.9993714644877436	>1
18	E	Y	All mutations	Y	1.9993714644877436	>1
18	E	H	All mutations	H	1.9993714644877436	>1
18	E	W	All mutations	W	2.0006285355122566	>1
18	E	I	All mutations	I	2.9993714644877434	>1
18	E	R	All mutations	R	2.0	>1
18	E	L	All mutations	L	2.0	>1
18	E	M	All mutations	M	2.0006285355122566	>1
18	E	S	All mutations	S	2.0	>1
19	I	D	All mutations	D	3.0	>1
19	I	M	All mutations	M	0.9949717159019484	1
19	I	G	All mutations	G	2.0	>1
19	I	C	All mutations	C	3.0	>1
19	I	E	All mutations	E	2.0	>1
19	I	F	All mutations	F	2.0	>1
19	I	K	All mutations	K	1.0	1
19	I	Y	All mutations	Y	3.0	>1
19	I	H	All mutations	H	3.0	>1
19	I	T	All mutations	T	1.0	1
19	I	A	All mutations	A	2.0	>1
19	I	P	All mutations	P	2.0	>1
19	I	Q	All mutations	Q	2.0	>1
19	I	N	All mutations	N	2.0	>1
19	I	W	All mutations	W	2.9949717159019484	>1
19	I	R	All mutations	R	1.0	1
19	I	V	All mutations	V	1.0	1
19	I	L	All mutations	L	1.0	1
19	I	I	All mutations	I	0.00502828409805154	1
19	I	S	All mutations	S	2.0	>1
20	L	K	All mutations	K	2.1401634192331866	>1
20	L	T	All mutations	T	2.0	>1
20	L	M	All mutations	M	1.6467630421118793	>1
20	L	V	All mutations	V	1.0	1
20	L	C	All mutations	C	2.8585795097423006	>1
20	L	G	All mutations	G	2.0	>1
20	L	R	All mutations	R	1.0012570710245128	1
20	L	W	All mutations	W	2.6455059710873665	>1
20	L	Y	All mutations	Y	2.8585795097423006	>1
20	L	Q	All mutations	Q	1.1414204902576996	>1
20	L	P	All mutations	P	1.0012570710245128	1
20	L	I	All mutations	I	1.3532369578881207	>1
20	L	A	All mutations	A	2.0	>1
20	L	E	All mutations	E	2.1401634192331866	>1
20	L	D	All mutations	D	2.8598365807668134	>1
20	L	F	All mutations	F	1.8585795097423004	>1
20	L	S	All mutations	S	1.9987429289754872	>1
20	L	H	All mutations	H	1.8610936517913261	>1
20	L	N	All mutations	N	2.8598365807668134	>1
20	L	L	All mutations	L	0.0	0
21	T	D	All mutations	D	2.527341294783155	>1
21	T	Y	All mutations	Y	2.525455688246386	>1
21	T	W	All mutations	W	2.996857322438718	>1
21	T	M	All mutations	M	1.9974858579509742	>1
21	T	N	All mutations	N	1.5292269013199247	>1
21	T	V	All mutations	V	1.9962287869264614	>1
21	T	C	All mutations	C	2.5386549340037714	>1
21	T	K	All mutations	K	1.4468887492143305	>1
21	T	E	All mutations	E	2.445003142677561	>1
21	T	A	All mutations	A	1.0182275298554369	1
21	T	P	All mutations	P	1.0182275298554369	1
21	T	I	All mutations	I	0.9987429289754871	1
21	T	T	All mutations	T	0.02011313639220616	1
21	T	R	All mutations	R	1.4600879949717158	>1
21	T	G	All mutations	G	1.9993714644877436	>1
21	T	S	All mutations	S	0.9987429289754871	1
21	T	L	All mutations	L	1.994343180389692	>1
21	T	H	All mutations	H	2.527341294783155	>1
21	T	Q	All mutations	Q	2.445003142677561	>1
21	T	F	All mutations	F	2.535512256442489	>1
22	K	H	All mutations	H	2.0163419233186675	>1
22	K	W	All mutations	W	2.8554368321810184	>1
22	K	I	All mutations	I	1.1269641734758014	>1
22	K	T	All mutations	T	1.0006285355122564	1
22	K	L	All mutations	L	2.0	>1
22	K	V	All mutations	V	2.0	>1
22	K	S	All mutations	S	1.9811439346323068	>1
22	K	Q	All mutations	Q	1.0188560653676932	1
22	K	Y	All mutations	Y	2.015713387806411	>1
22	K	M	All mutations	M	1.8742928975487114	>1
22	K	N	All mutations	N	1.0169704588309239	1
22	K	G	All mutations	G	1.9824010056568195	>1
22	K	E	All mutations	E	1.0188560653676932	1
22	K	D	All mutations	D	2.0163419233186675	>1
22	K	R	All mutations	R	0.9836580766813325	1
22	K	K	All mutations	K	0.01948460087994972	1
22	K	F	All mutations	F	2.9981143934632306	>1
22	K	C	All mutations	C	2.9805153991200504	>1
22	K	P	All mutations	P	2.0	>1
22	K	A	All mutations	A	2.0	>1
23	T	L	All mutations	L	1.9987429289754872	>1
23	T	Y	All mutations	Y	2.1024512884978	>1
23	T	M	All mutations	M	2.001257071024513	>1
23	T	I	All mutations	I	1.0012570710245128	1
23	T	C	All mutations	C	2.1030798240100568	>1
23	T	V	All mutations	V	2.0	>1
23	T	G	All mutations	G	2.0	>1
23	T	S	All mutations	S	1.0006285355122564	1
23	T	Q	All mutations	Q	2.8950345694531743	>1
23	T	N	All mutations	N	1.103708359522313	>1
23	T	H	All mutations	H	2.1011942174732874	>1
23	T	P	All mutations	P	0.9993714644877436	1
23	T	D	All mutations	D	2.1024512884978	>1
23	T	F	All mutations	F	2.1030798240100568	>1
23	T	T	All mutations	T	0.0018856065367693275	1
23	T	E	All mutations	E	2.896291640477687	>1
23	T	R	All mutations	R	1.896291640477687	>1
23	T	W	All mutations	W	3.0	>1
23	T	K	All mutations	K	1.8975487115021998	>1
23	T	A	All mutations	A	1.0006285355122564	1
24	T	A	All mutations	A	1.0	1
24	T	C	All mutations	C	2.054054054054054	>1
24	T	K	All mutations	K	1.945945945945946	>1
24	T	G	All mutations	G	2.0	>1
24	T	E	All mutations	E	2.945945945945946	>1
24	T	P	All mutations	P	1.0	1
24	T	D	All mutations	D	2.054054054054054	>1
24	T	M	All mutations	M	1.9956002514142048	>1
24	T	N	All mutations	N	1.054054054054054	1
24	T	Q	All mutations	Q	2.945945945945946	>1
24	T	Y	All mutations	Y	2.054054054054054	>1
24	T	H	All mutations	H	2.054054054054054	>1
24	T	R	All mutations	R	1.945945945945946	>1
24	T	S	All mutations	S	1.0	1
24	T	L	All mutations	L	2.0	>1
24	T	V	All mutations	V	2.0	>1
24	T	W	All mutations	W	2.995600251414205	>1
24	T	I	All mutations	I	1.0043997485857952	1
24	T	F	All mutations	F	2.054054054054054	>1
24	T	T	All mutations	T	0.0	0
25	V	F	All mutations	F	1.6656191074795725	>1
25	V	P	All mutations	P	2.0	>1
25	V	M	All mutations	M	1.3695788812067882	>1
25	V	D	All mutations	D	1.6656191074795725	>1
25	V	W	All mutations	W	2.369578881206788	>1
25	V	S	All mutations	S	2.0	>1
25	V	R	All mutations	R	2.0	>1
25	V	N	All mutations	N	2.6656191074795728	>1
25	V	G	All mutations	G	1.0	1
25	V	H	All mutations	H	2.6656191074795728	>1
25	V	E	All mutations	E	1.3343808925204275	>1
25	V	Q	All mutations	Q	2.3343808925204272	>1
25	V	C	All mutations	C	2.6656191074795728	>1
25	V	I	All mutations	I	1.6304211187932118	>1
25	V	K	All mutations	K	2.3343808925204272	>1
25	V	A	All mutations	A	1.0	1
25	V	V	All mutations	V	0.0	0
25	V	T	All mutations	T	2.0	>1
25	V	L	All mutations	L	1.0	1
25	V	Y	All mutations	Y	2.6656191074795728	>1
26	D	T	All mutations	T	2.0	>1
26	D	N	All mutations	N	1.0	1
26	D	R	All mutations	R	2.0	>1
26	D	A	All mutations	A	1.0	1
26	D	K	All mutations	K	2.0	>1
26	D	F	All mutations	F	2.0	>1
26	D	P	All mutations	P	2.0	>1
26	D	E	All mutations	E	1.0	1
26	D	L	All mutations	L	2.0	>1
26	D	D	All mutations	D	0.0	0
26	D	W	All mutations	W	3.0	>1
26	D	I	All mutations	I	2.0	>1
26	D	G	All mutations	G	1.0	1
26	D	V	All mutations	V	1.0	1
26	D	Q	All mutations	Q	2.0	>1
26	D	S	All mutations	S	2.0	>1
26	D	C	All mutations	C	2.0	>1
26	D	H	All mutations	H	1.0	1
26	D	M	All mutations	M	3.0	>1
26	D	Y	All mutations	Y	1.0	1
27	H	G	All mutations	G	2.0	>1
27	H	K	All mutations	K	2.0	>1
27	H	C	All mutations	C	2.0	>1
27	H	Y	All mutations	Y	1.0	1
27	H	M	All mutations	M	3.0	>1
27	H	W	All mutations	W	3.0	>1
27	H	P	All mutations	P	1.0	1
27	H	R	All mutations	R	1.0	1
27	H	L	All mutations	L	1.0	1
27	H	H	All mutations	H	0.0	0
27	H	A	All mutations	A	2.0	>1
27	H	Q	All mutations	Q	1.0	1
27	H	E	All mutations	E	2.0	>1
27	H	T	All mutations	T	2.0	>1
27	H	N	All mutations	N	1.0	1
27	H	V	All mutations	V	2.0	>1
27	H	I	All mutations	I	2.0	>1
27	H	F	All mutations	F	2.0	>1
27	H	D	All mutations	D	1.0	1
27	H	S	All mutations	S	2.0	>1
28	M	E	All mutations	E	2.0006285355122566	>1
28	M	Y	All mutations	Y	2.9993714644877434	>1
28	M	C	All mutations	C	2.9993714644877434	>1
28	M	G	All mutations	G	2.0	>1
28	M	Q	All mutations	Q	2.0006285355122566	>1
28	M	D	All mutations	D	2.9993714644877434	>1
28	M	T	All mutations	T	1.0	1
28	M	N	All mutations	N	1.9993714644877436	>1
28	M	A	All mutations	A	2.0	>1
28	M	L	All mutations	L	1.0	1
28	M	M	All mutations	M	0.0006285355122564425	1
28	M	S	All mutations	S	1.9993714644877436	>1
28	M	W	All mutations	W	2.0006285355122566	>1
28	M	R	All mutations	R	1.0006285355122564	1
28	M	H	All mutations	H	2.9993714644877434	>1
28	M	F	All mutations	F	1.9993714644877436	>1
28	M	K	All mutations	K	1.0006285355122564	1
28	M	I	All mutations	I	0.9993714644877436	1
28	M	V	All mutations	V	1.0	1
28	M	P	All mutations	P	2.0	>1
29	A	V	All mutations	V	1.0	1
29	A	Q	All mutations	Q	2.9893148962916403	>1
29	A	E	All mutations	E	1.9893148962916405	>1
29	A	N	All mutations	N	2.0106851037083597	>1
29	A	F	All mutations	F	2.0106851037083597	>1
29	A	A	All mutations	A	0.0	0
29	A	G	All mutations	G	1.0	1
29	A	M	All mutations	M	3.0	>1
29	A	S	All mutations	S	1.0	1
29	A	L	All mutations	L	2.0	>1
29	A	H	All mutations	H	2.0106851037083597	>1
29	A	T	All mutations	T	1.0	1
29	A	W	All mutations	W	3.0	>1
29	A	Y	All mutations	Y	2.0106851037083597	>1
29	A	I	All mutations	I	2.0	>1
29	A	C	All mutations	C	2.0106851037083597	>1
29	A	D	All mutations	D	1.0106851037083595	1
29	A	R	All mutations	R	2.0	>1
29	A	P	All mutations	P	1.0	1
29	A	K	All mutations	K	2.9893148962916403	>1
30	I	W	All mutations	W	3.0	>1
30	I	A	All mutations	A	1.984286612193589	>1
30	I	V	All mutations	V	0.9842866121935889	1
30	I	L	All mutations	L	1.0	1
30	I	S	All mutations	S	1.9893148962916405	>1
30	I	R	All mutations	R	1.0263984915147706	1
30	I	H	All mutations	H	2.9893148962916403	>1
30	I	C	All mutations	C	2.9893148962916403	>1
30	I	G	All mutations	G	1.984286612193589	>1
30	I	I	All mutations	I	0.01571338780641106	1
30	I	F	All mutations	F	1.9893148962916405	>1
30	I	K	All mutations	K	1.0263984915147706	1
30	I	T	All mutations	T	1.015713387806411	1
30	I	D	All mutations	D	2.9736015084852294	>1
30	I	Y	All mutations	Y	2.9893148962916403	>1
30	I	E	All mutations	E	1.9949717159019484	>1
30	I	N	All mutations	N	2.0050282840980516	>1
30	I	P	All mutations	P	2.0	>1
30	I	M	All mutations	M	1.015713387806411	1
30	I	Q	All mutations	Q	2.0106851037083597	>1
31	I	H	All mutations	H	2.0898805782526715	>1
31	I	T	All mutations	T	1.0	1
31	I	Q	All mutations	Q	2.9101194217473285	>1
31	I	Y	All mutations	Y	2.0898805782526715	>1
31	I	V	All mutations	V	1.0	1
31	I	I	All mutations	I	0.0	0
31	I	L	All mutations	L	1.0	1
31	I	C	All mutations	C	2.0898805782526715	>1
31	I	G	All mutations	G	2.0	>1
31	I	R	All mutations	R	1.9101194217473287	>1
31	I	F	All mutations	F	1.0898805782526713	1
31	I	P	All mutations	P	2.0	>1
31	I	N	All mutations	N	1.0898805782526713	1
31	I	A	All mutations	A	2.0	>1
31	I	E	All mutations	E	2.9101194217473285	>1
31	I	K	All mutations	K	1.9101194217473287	>1
31	I	W	All mutations	W	3.0	>1
31	I	S	All mutations	S	1.0898805782526713	1
31	I	M	All mutations	M	1.0	1
31	I	D	All mutations	D	2.0898805782526715	>1
32	K	H	All mutations	H	2.0006285355122566	>1
32	K	E	All mutations	E	1.0006285355122564	1
32	K	Y	All mutations	Y	2.0006285355122566	>1
32	K	D	All mutations	D	2.0006285355122566	>1
32	K	W	All mutations	W	2.463230672532998	>1
32	K	R	All mutations	R	0.9993714644877436	1
32	K	K	All mutations	K	0.0006285355122564425	1
32	K	P	All mutations	P	2.0	>1
32	K	F	All mutations	F	3.0	>1
32	K	I	All mutations	I	1.5361407919547454	>1
32	K	V	All mutations	V	2.0	>1
32	K	Q	All mutations	Q	1.0006285355122564	1
32	K	A	All mutations	A	2.0	>1
32	K	M	All mutations	M	1.4638592080452546	>1
32	K	C	All mutations	C	2.9993714644877434	>1
32	K	N	All mutations	N	1.0006285355122564	1
32	K	T	All mutations	T	1.0	1
32	K	L	All mutations	L	2.0	>1
32	K	G	All mutations	G	1.9993714644877436	>1
32	K	S	All mutations	S	1.9993714644877436	>1
33	K	K	All mutations	K	0.0006285355122564425	1
33	K	I	All mutations	I	1.4123192960402262	>1
33	K	C	All mutations	C	2.9993714644877434	>1
33	K	A	All mutations	A	2.0	>1
33	K	N	All mutations	N	1.0006285355122564	1
33	K	P	All mutations	P	2.0	>1
33	K	L	All mutations	L	2.0	>1
33	K	R	All mutations	R	0.9993714644877436	1
33	K	S	All mutations	S	1.9993714644877436	>1
33	K	Q	All mutations	Q	1.0006285355122564	1
33	K	V	All mutations	V	2.0	>1
33	K	F	All mutations	F	3.0	>1
33	K	D	All mutations	D	2.0006285355122566	>1
33	K	G	All mutations	G	1.9993714644877436	>1
33	K	M	All mutations	M	1.5876807039597738	>1
33	K	Y	All mutations	Y	2.0006285355122566	>1
33	K	T	All mutations	T	1.0	1
33	K	H	All mutations	H	2.0006285355122566	>1
33	K	W	All mutations	W	2.587052168447517	>1
33	K	E	All mutations	E	1.0006285355122564	1
34	Y	T	All mutations	T	2.0	>1
34	Y	A	All mutations	A	2.0	>1
34	Y	E	All mutations	E	2.0	>1
34	Y	K	All mutations	K	2.0	>1
34	Y	H	All mutations	H	1.0	1
34	Y	L	All mutations	L	2.0	>1
34	Y	F	All mutations	F	1.0	1
34	Y	C	All mutations	C	1.0	1
34	Y	D	All mutations	D	1.0	1
34	Y	R	All mutations	R	2.0	>1
34	Y	M	All mutations	M	3.0	>1
34	Y	S	All mutations	S	1.0	1
34	Y	N	All mutations	N	1.0	1
34	Y	P	All mutations	P	2.0	>1
34	Y	G	All mutations	G	2.0	>1
34	Y	W	All mutations	W	2.0	>1
34	Y	Q	All mutations	Q	2.0	>1
34	Y	I	All mutations	I	2.0	>1
34	Y	V	All mutations	V	2.0	>1
34	Y	Y	All mutations	Y	0.0	0
35	T	F	All mutations	F	2.9692017598994345	>1
35	T	E	All mutations	E	2.0307982401005655	>1
35	T	D	All mutations	D	2.9692017598994345	>1
35	T	T	All mutations	T	0.0	0
35	T	I	All mutations	I	1.0873664362036455	1
35	T	R	All mutations	R	1.0307982401005658	1
35	T	M	All mutations	M	1.9126335637963545	>1
35	T	Y	All mutations	Y	2.9692017598994345	>1
35	T	S	All mutations	S	1.0	1
35	T	K	All mutations	K	1.0307982401005658	1
35	T	C	All mutations	C	2.9692017598994345	>1
35	T	Q	All mutations	Q	2.0307982401005655	>1
35	T	A	All mutations	A	1.0	1
35	T	L	All mutations	L	2.0	>1
35	T	W	All mutations	W	2.9126335637963545	>1
35	T	N	All mutations	N	1.9692017598994342	>1
35	T	P	All mutations	P	1.0	1
35	T	V	All mutations	V	2.0	>1
35	T	H	All mutations	H	2.9692017598994345	>1
35	T	G	All mutations	G	2.0	>1
36	S	P	All mutations	P	1.0	1
36	S	F	All mutations	F	1.994343180389692	>1
36	S	R	All mutations	R	1.9987429289754872	>1
36	S	I	All mutations	I	2.4965430546825895	>1
36	S	S	All mutations	S	0.001257071024512885	1
36	S	T	All mutations	T	0.9987429289754871	1
36	S	W	All mutations	W	1.5034569453174105	>1
36	S	L	All mutations	L	1.0081709616593337	1
36	S	M	All mutations	M	2.5009428032683845	>1
36	S	C	All mutations	C	1.994343180389692	>1
36	S	H	All mutations	H	2.993086109365179	>1
36	S	N	All mutations	N	2.9918290383406663	>1
36	S	V	All mutations	V	2.0	>1
36	S	G	All mutations	G	2.0	>1
36	S	Q	All mutations	Q	2.006913890634821	>1
36	S	D	All mutations	D	2.993086109365179	>1
36	S	K	All mutations	K	2.005656819610308	>1
36	S	E	All mutations	E	2.006913890634821	>1
36	S	Y	All mutations	Y	1.994343180389692	>1
36	S	A	All mutations	A	1.0	1
37	G	S	All mutations	S	1.9937146448774357	>1
37	G	A	All mutations	A	1.0	1
37	G	Q	All mutations	Q	2.0062853551225643	>1
37	G	Y	All mutations	Y	2.9937146448774357	>1
37	G	C	All mutations	C	1.9937146448774357	>1
37	G	G	All mutations	G	0.0	0
37	G	R	All mutations	R	1.0	1
37	G	P	All mutations	P	2.0	>1
37	G	F	All mutations	F	2.9937146448774357	>1
37	G	T	All mutations	T	2.0	>1
37	G	E	All mutations	E	1.0062853551225643	1
37	G	V	All mutations	V	1.0	1
37	G	N	All mutations	N	2.9937146448774357	>1
37	G	D	All mutations	D	1.9937146448774357	>1
37	G	W	All mutations	W	1.957259585166562	>1
37	G	L	All mutations	L	2.0	>1
37	G	I	All mutations	I	2.042740414833438	>1
37	G	H	All mutations	H	2.9937146448774357	>1
37	G	M	All mutations	M	2.957259585166562	>1
37	G	K	All mutations	K	2.0062853551225643	>1
38	R	G	All mutations	G	1.0	1
38	R	W	All mutations	W	1.473287240729101	>1
38	R	D	All mutations	D	3.0	>1
38	R	C	All mutations	C	2.0	>1
38	R	N	All mutations	N	2.001257071024513	>1
38	R	Y	All mutations	Y	3.0	>1
38	R	Q	All mutations	Q	1.9987429289754872	>1
38	R	T	All mutations	T	1.0012570710245128	1
38	R	L	All mutations	L	1.9987429289754872	>1
38	R	K	All mutations	K	1.0012570710245128	1
38	R	P	All mutations	P	1.9987429289754872	>1
38	R	R	All mutations	R	0.0	0
38	R	E	All mutations	E	2.0	>1
38	R	I	All mutations	I	1.5279698302954117	>1
38	R	H	All mutations	H	2.998742928975487	>1
38	R	A	All mutations	A	2.0	>1
38	R	F	All mutations	F	3.0	>1
38	R	V	All mutations	V	2.0	>1
38	R	S	All mutations	S	1.0012570710245128	1
38	R	M	All mutations	M	1.4745443117536141	>1
39	Q	V	All mutations	V	2.0	>1
39	Q	I	All mutations	I	2.352608422375864	>1
39	Q	D	All mutations	D	2.0	>1
39	Q	S	All mutations	S	2.0	>1
39	Q	C	All mutations	C	3.0	>1
39	Q	G	All mutations	G	2.0	>1
39	Q	F	All mutations	F	3.0	>1
39	Q	E	All mutations	E	1.0	1
39	Q	K	All mutations	K	1.0	1
39	Q	W	All mutations	W	2.647391577624136	>1
39	Q	R	All mutations	R	1.0	1
39	Q	P	All mutations	P	1.0	1
39	Q	N	All mutations	N	2.0	>1
39	Q	Q	All mutations	Q	0.0	0
39	Q	T	All mutations	T	2.0	>1
39	Q	H	All mutations	H	1.0	1
39	Q	Y	All mutations	Y	2.0	>1
39	Q	L	All mutations	L	1.0	1
39	Q	A	All mutations	A	2.0	>1
39	Q	M	All mutations	M	2.647391577624136	>1
40	E	L	All mutations	L	2.0	>1
40	E	E	All mutations	E	0.0	0
40	E	H	All mutations	H	2.0	>1
40	E	R	All mutations	R	2.0	>1
40	E	C	All mutations	C	3.0	>1
40	E	Y	All mutations	Y	2.0	>1
40	E	N	All mutations	N	2.0	>1
40	E	I	All mutations	I	2.8799497171590196	>1
40	E	S	All mutations	S	2.0	>1
40	E	G	All mutations	G	1.0	1
40	E	D	All mutations	D	1.0	1
40	E	A	All mutations	A	1.0	1
40	E	M	All mutations	M	2.1200502828409804	>1
40	E	W	All mutations	W	2.1200502828409804	>1
40	E	K	All mutations	K	1.0	1
40	E	Q	All mutations	Q	1.0	1
40	E	V	All mutations	V	1.0	1
40	E	F	All mutations	F	3.0	>1
40	E	P	All mutations	P	2.0	>1
40	E	T	All mutations	T	2.0	>1
41	K	M	All mutations	M	1.032683846637335	1
41	K	E	All mutations	E	1.0006285355122564	1
41	K	R	All mutations	R	0.9993714644877436	1
41	K	K	All mutations	K	0.0006285355122564425	1
41	K	S	All mutations	S	1.9993714644877436	>1
41	K	F	All mutations	F	3.0	>1
41	K	N	All mutations	N	1.0006285355122564	1
41	K	V	All mutations	V	2.0	>1
41	K	P	All mutations	P	2.0	>1
41	K	G	All mutations	G	1.9993714644877436	>1
41	K	A	All mutations	A	2.0	>1
41	K	I	All mutations	I	1.967316153362665	>1
41	K	L	All mutations	L	2.0	>1
41	K	Q	All mutations	Q	1.0006285355122564	1
41	K	W	All mutations	W	2.0320553111250788	>1
41	K	T	All mutations	T	1.0	1
41	K	H	All mutations	H	2.0006285355122566	>1
41	K	D	All mutations	D	2.0006285355122566	>1
41	K	Y	All mutations	Y	2.0006285355122566	>1
41	K	C	All mutations	C	2.9993714644877434	>1
42	N	L	All mutations	L	2.0	>1
42	N	V	All mutations	V	2.0	>1
42	N	P	All mutations	P	2.0	>1
42	N	T	All mutations	T	1.0	1
42	N	Q	All mutations	Q	2.0	>1
42	N	F	All mutations	F	2.0	>1
42	N	A	All mutations	A	2.0	>1
42	N	W	All mutations	W	3.0	>1
42	N	I	All mutations	I	1.0	1
42	N	H	All mutations	H	1.0	1
42	N	D	All mutations	D	1.0	1
42	N	E	All mutations	E	2.0	>1
42	N	K	All mutations	K	1.0	1
42	N	G	All mutations	G	2.0	>1
42	N	C	All mutations	C	2.0	>1
42	N	R	All mutations	R	2.0	>1
42	N	M	All mutations	M	2.0	>1
42	N	S	All mutations	S	1.0	1
42	N	Y	All mutations	Y	1.0	1
42	N	N	All mutations	N	0.0	0
43	P	S	All mutations	S	1.0	1
43	P	E	All mutations	E	2.974858579509742	>1
43	P	K	All mutations	K	2.974858579509742	>1
43	P	F	All mutations	F	2.025141420490258	>1
43	P	I	All mutations	I	2.011313639220616	>1
43	P	T	All mutations	T	1.0	1
43	P	H	All mutations	H	1.0251414204902578	1
43	P	V	All mutations	V	2.0	>1
43	P	G	All mutations	G	2.0	>1
43	P	L	All mutations	L	1.0	1
43	P	Y	All mutations	Y	2.025141420490258	>1
43	P	C	All mutations	C	2.025141420490258	>1
43	P	D	All mutations	D	2.025141420490258	>1
43	P	W	All mutations	W	2.988686360779384	>1
43	P	R	All mutations	R	1.0	1
43	P	N	All mutations	N	2.025141420490258	>1
43	P	M	All mutations	M	2.988686360779384	>1
43	P	A	All mutations	A	1.0	1
43	P	P	All mutations	P	0.0	0
43	P	Q	All mutations	Q	1.9748585795097422	>1
44	A	Q	All mutations	Q	2.5034569453174105	>1
44	A	F	All mutations	F	2.4965430546825895	>1
44	A	Y	All mutations	Y	2.4965430546825895	>1
44	A	G	All mutations	G	1.0006285355122564	1
44	A	A	All mutations	A	0.0006285355122564425	1
44	A	C	All mutations	C	2.4965430546825895	>1
44	A	E	All mutations	E	1.5040854808296669	>1
44	A	D	All mutations	D	1.497171590194846	>1
44	A	P	All mutations	P	1.0	1
44	A	W	All mutations	W	2.9824010056568198	>1
44	A	M	All mutations	M	2.981772470144563	>1
44	A	S	All mutations	S	1.0	1
44	A	I	All mutations	I	2.016970458830924	>1
44	A	L	All mutations	L	2.0	>1
44	A	R	All mutations	R	1.9993714644877436	>1
44	A	V	All mutations	V	1.0006285355122564	1
44	A	N	All mutations	N	2.495914519170333	>1
44	A	H	All mutations	H	2.4965430546825895	>1
44	A	K	All mutations	K	2.502828409805154	>1
44	A	T	All mutations	T	0.9993714644877436	1
45	L	K	All mutations	K	2.9974858579509744	>1
45	L	D	All mutations	D	2.0025141420490256	>1
45	L	M	All mutations	M	2.0	>1
45	L	N	All mutations	N	2.0025141420490256	>1
45	L	V	All mutations	V	1.0	1
45	L	L	All mutations	L	0.0	0
45	L	E	All mutations	E	2.9974858579509744	>1
45	L	W	All mutations	W	3.0	>1
45	L	T	All mutations	T	2.0	>1
45	L	S	All mutations	S	2.0	>1
45	L	C	All mutations	C	2.0025141420490256	>1
45	L	G	All mutations	G	2.0	>1
45	L	I	All mutations	I	1.0	1
45	L	P	All mutations	P	1.0	1
45	L	A	All mutations	A	2.0	>1
45	L	H	All mutations	H	1.0025141420490258	1
45	L	F	All mutations	F	1.0025141420490258	1
45	L	Y	All mutations	Y	2.0025141420490256	>1
45	L	Q	All mutations	Q	1.9974858579509742	>1
45	L	R	All mutations	R	1.0	1
46	R	K	All mutations	K	1.0	1
46	R	V	All mutations	V	2.0	>1
46	R	F	All mutations	F	3.0	>1
46	R	P	All mutations	P	2.0	>1
46	R	R	All mutations	R	0.0	0
46	R	M	All mutations	M	1.2482715273412948	>1
46	R	Y	All mutations	Y	3.0	>1
46	R	D	All mutations	D	3.0	>1
46	R	C	All mutations	C	2.0	>1
46	R	L	All mutations	L	2.0	>1
46	R	Q	All mutations	Q	2.0	>1
46	R	S	All mutations	S	1.0	1
46	R	W	All mutations	W	1.2482715273412948	>1
46	R	I	All mutations	I	1.7517284726587052	>1
46	R	T	All mutations	T	1.0	1
46	R	N	All mutations	N	2.0	>1
46	R	A	All mutations	A	2.0	>1
46	R	H	All mutations	H	3.0	>1
46	R	E	All mutations	E	2.0	>1
46	R	G	All mutations	G	1.0	1
47	M	G	All mutations	G	2.0	>1
47	M	D	All mutations	D	3.0	>1
47	M	Y	All mutations	Y	3.0	>1
47	M	W	All mutations	W	2.001257071024513	>1
47	M	L	All mutations	L	1.0006285355122564	1
47	M	R	All mutations	R	1.0	1
47	M	C	All mutations	C	3.0	>1
47	M	K	All mutations	K	1.0	1
47	M	N	All mutations	N	2.0	>1
47	M	S	All mutations	S	1.9993714644877436	>1
47	M	F	All mutations	F	2.0006285355122566	>1
47	M	Q	All mutations	Q	2.0	>1
47	M	H	All mutations	H	3.0	>1
47	M	E	All mutations	E	2.0	>1
47	M	I	All mutations	I	0.9993714644877436	1
47	M	V	All mutations	V	1.0006285355122564	1
47	M	M	All mutations	M	0.0018856065367693275	1
47	M	T	All mutations	T	0.9993714644877436	1
47	M	A	All mutations	A	1.9993714644877436	>1
47	M	P	All mutations	P	1.9993714644877436	>1
48	K	G	All mutations	G	2.0	>1
48	K	E	All mutations	E	1.0	1
48	K	L	All mutations	L	2.0	>1
48	K	T	All mutations	T	1.0	1
48	K	K	All mutations	K	0.0	0
48	K	I	All mutations	I	1.2023884349465745	>1
48	K	Q	All mutations	Q	1.0	1
48	K	W	All mutations	W	2.7976115650534257	>1
48	K	A	All mutations	A	2.0	>1
48	K	H	All mutations	H	2.0	>1
48	K	N	All mutations	N	1.0	1
48	K	F	All mutations	F	3.0	>1
48	K	D	All mutations	D	2.0	>1
48	K	Y	All mutations	Y	2.0	>1
48	K	P	All mutations	P	2.0	>1
48	K	C	All mutations	C	3.0	>1
48	K	M	All mutations	M	1.7976115650534255	>1
48	K	V	All mutations	V	2.0	>1
48	K	R	All mutations	R	1.0	1
48	K	S	All mutations	S	2.0	>1
49	W	A	All mutations	A	2.0	>1
49	W	W	All mutations	W	0.0	0
49	W	M	All mutations	M	2.0	>1
49	W	Y	All mutations	Y	2.0	>1
49	W	K	All mutations	K	2.0	>1
49	W	H	All mutations	H	3.0	>1
49	W	I	All mutations	I	3.0	>1
49	W	D	All mutations	D	3.0	>1
49	W	V	All mutations	V	2.0	>1
49	W	Q	All mutations	Q	2.0	>1
49	W	F	All mutations	F	2.0	>1
49	W	N	All mutations	N	3.0	>1
49	W	S	All mutations	S	1.0	1
49	W	R	All mutations	R	1.0	1
49	W	C	All mutations	C	1.0	1
49	W	E	All mutations	E	2.0	>1
49	W	G	All mutations	G	1.0	1
49	W	L	All mutations	L	1.0	1
49	W	T	All mutations	T	2.0	>1
49	W	P	All mutations	P	2.0	>1
50	M	F	All mutations	F	2.0006285355122566	>1
50	M	E	All mutations	E	1.9993714644877436	>1
50	M	H	All mutations	H	3.0	>1
50	M	T	All mutations	T	1.0006285355122564	1
50	M	S	All mutations	S	1.9993714644877436	>1
50	M	Q	All mutations	Q	2.0	>1
50	M	M	All mutations	M	0.001257071024512885	1
50	M	V	All mutations	V	1.0	1
50	M	N	All mutations	N	2.0006285355122566	>1
50	M	R	All mutations	R	1.0	1
50	M	D	All mutations	D	2.9993714644877434	>1
50	M	I	All mutations	I	1.0012570710245128	1
50	M	W	All mutations	W	1.9993714644877436	>1
50	M	L	All mutations	L	1.0006285355122564	1
50	M	G	All mutations	G	1.9987429289754872	>1
50	M	P	All mutations	P	2.0	>1
50	M	A	All mutations	A	1.9993714644877436	>1
50	M	K	All mutations	K	1.0006285355122564	1
50	M	Y	All mutations	Y	3.0	>1
50	M	C	All mutations	C	2.9993714644877434	>1
51	M	H	All mutations	H	3.0	>1
51	M	Y	All mutations	Y	3.0	>1
51	M	Q	All mutations	Q	2.0	>1
51	M	G	All mutations	G	2.0	>1
51	M	C	All mutations	C	3.0	>1
51	M	R	All mutations	R	1.0	1
51	M	P	All mutations	P	2.0	>1
51	M	A	All mutations	A	2.0	>1
51	M	W	All mutations	W	2.0	>1
51	M	S	All mutations	S	2.0	>1
51	M	L	All mutations	L	1.0	1
51	M	I	All mutations	I	1.0	1
51	M	K	All mutations	K	1.0	1
51	M	T	All mutations	T	1.0	1
51	M	E	All mutations	E	2.0	>1
51	M	V	All mutations	V	1.0	1
51	M	N	All mutations	N	2.0	>1
51	M	F	All mutations	F	2.0	>1
51	M	M	All mutations	M	0.0	0
51	M	D	All mutations	D	3.0	>1
52	A	T	All mutations	T	1.0	1
52	A	V	All mutations	V	1.0	1
52	A	E	All mutations	E	1.0037712130735386	1
52	A	K	All mutations	K	2.003771213073539	>1
52	A	A	All mutations	A	0.0	0
52	A	C	All mutations	C	2.996228786926461	>1
52	A	G	All mutations	G	1.0	1
52	A	I	All mutations	I	2.087994971715902	>1
52	A	N	All mutations	N	2.996228786926461	>1
52	A	P	All mutations	P	1.0	1
52	A	D	All mutations	D	1.9962287869264614	>1
52	A	W	All mutations	W	2.912005028284098	>1
52	A	S	All mutations	S	1.0	1
52	A	F	All mutations	F	2.996228786926461	>1
52	A	Y	All mutations	Y	2.996228786926461	>1
52	A	H	All mutations	H	2.996228786926461	>1
52	A	R	All mutations	R	2.0	>1
52	A	L	All mutations	L	2.0	>1
52	A	Q	All mutations	Q	2.003771213073539	>1
52	A	M	All mutations	M	2.912005028284098	>1
53	M	Y	All mutations	Y	3.0	>1
53	M	F	All mutations	F	2.0	>1
53	M	S	All mutations	S	2.0	>1
53	M	W	All mutations	W	2.0	>1
53	M	D	All mutations	D	2.9993714644877434	>1
53	M	P	All mutations	P	2.0	>1
53	M	G	All mutations	G	1.9993714644877436	>1
53	M	R	All mutations	R	1.0006285355122564	1
53	M	N	All mutations	N	2.0006285355122566	>1
53	M	Q	All mutations	Q	2.0	>1
53	M	L	All mutations	L	1.0	1
53	M	M	All mutations	M	0.0006285355122564425	1
53	M	C	All mutations	C	3.0	>1
53	M	A	All mutations	A	1.9993714644877436	>1
53	M	H	All mutations	H	3.0	>1
53	M	K	All mutations	K	1.0006285355122564	1
53	M	T	All mutations	T	1.0006285355122564	1
53	M	V	All mutations	V	0.9993714644877436	1
53	M	I	All mutations	I	1.0006285355122564	1
53	M	E	All mutations	E	1.9993714644877436	>1
54	K	R	All mutations	R	0.9949717159019484	1
54	K	T	All mutations	T	1.0	1
54	K	H	All mutations	H	2.0050282840980516	>1
54	K	P	All mutations	P	2.0	>1
54	K	I	All mutations	I	1.1213073538654934	>1
54	K	D	All mutations	D	2.0050282840980516	>1
54	K	N	All mutations	N	1.0050282840980516	1
54	K	W	All mutations	W	2.8736643620364553	>1
54	K	K	All mutations	K	0.00502828409805154	1
54	K	L	All mutations	L	2.0	>1
54	K	E	All mutations	E	1.0050282840980516	1
54	K	C	All mutations	C	2.9949717159019484	>1
54	K	Q	All mutations	Q	1.0050282840980516	1
54	K	Y	All mutations	Y	2.0050282840980516	>1
54	K	S	All mutations	S	1.9949717159019484	>1
54	K	M	All mutations	M	1.8786926461345066	>1
54	K	F	All mutations	F	3.0	>1
54	K	A	All mutations	A	2.0	>1
54	K	V	All mutations	V	2.0	>1
54	K	G	All mutations	G	1.9949717159019484	>1
55	Y	N	All mutations	N	1.0	1
55	Y	I	All mutations	I	2.0	>1
55	Y	V	All mutations	V	2.0	>1
55	Y	S	All mutations	S	1.0012570710245128	1
55	Y	Y	All mutations	Y	0.001257071024512885	1
55	Y	Q	All mutations	Q	1.9987429289754872	>1
55	Y	P	All mutations	P	1.9987429289754872	>1
55	Y	F	All mutations	F	1.0012570710245128	1
55	Y	W	All mutations	W	2.001257071024513	>1
55	Y	T	All mutations	T	2.0	>1
55	Y	L	All mutations	L	1.9987429289754872	>1
55	Y	C	All mutations	C	1.0012570710245128	1
55	Y	E	All mutations	E	2.0	>1
55	Y	A	All mutations	A	2.0	>1
55	Y	M	All mutations	M	3.0	>1
55	Y	K	All mutations	K	2.0	>1
55	Y	G	All mutations	G	2.0	>1
55	Y	D	All mutations	D	1.0	1
55	Y	R	All mutations	R	1.9987429289754872	>1
55	Y	H	All mutations	H	0.9987429289754871	1
56	P	C	All mutations	C	2.9704588309239472	>1
56	P	L	All mutations	L	1.0	1
56	P	K	All mutations	K	2.0295411690760528	>1
56	P	A	All mutations	A	1.0	1
56	P	Q	All mutations	Q	1.0295411690760528	1
56	P	F	All mutations	F	2.9704588309239472	>1
56	P	V	All mutations	V	2.0	>1
56	P	T	All mutations	T	1.0	1
56	P	Y	All mutations	Y	2.9704588309239472	>1
56	P	G	All mutations	G	2.0	>1
56	P	M	All mutations	M	2.761785040854808	>1
56	P	W	All mutations	W	2.761785040854808	>1
56	P	H	All mutations	H	1.9704588309239472	>1
56	P	I	All mutations	I	2.238214959145192	>1
56	P	E	All mutations	E	2.0295411690760528	>1
56	P	N	All mutations	N	2.9704588309239472	>1
56	P	P	All mutations	P	0.0	0
56	P	S	All mutations	S	1.0	1
56	P	R	All mutations	R	1.0	1
56	P	D	All mutations	D	2.9704588309239472	>1
57	I	C	All mutations	C	2.0188560653676935	>1
57	I	Q	All mutations	Q	2.9805153991200504	>1
57	I	F	All mutations	F	1.0188560653676932	1
57	I	P	All mutations	P	1.9993714644877436	>1
57	I	E	All mutations	E	2.9811439346323065	>1
57	I	V	All mutations	V	1.0	1
57	I	R	All mutations	R	1.9805153991200504	>1
57	I	W	All mutations	W	3.0	>1
57	I	G	All mutations	G	2.0	>1
57	I	Y	All mutations	Y	2.0188560653676935	>1
57	I	I	All mutations	I	0.0006285355122564425	1
57	I	S	All mutations	S	1.0194846008799496	1
57	I	T	All mutations	T	1.0006285355122564	1
57	I	H	All mutations	H	2.018227529855437	>1
57	I	D	All mutations	D	2.0188560653676935	>1
57	I	M	All mutations	M	1.0006285355122564	1
57	I	A	All mutations	A	2.0	>1
57	I	L	All mutations	L	0.9993714644877436	1
57	I	N	All mutations	N	1.0194846008799496	1
57	I	K	All mutations	K	1.9817724701445631	>1
58	T	S	All mutations	S	1.0	1
58	T	W	All mutations	W	2.9893148962916403	>1
58	T	D	All mutations	D	2.9880578252671275	>1
58	T	L	All mutations	L	2.0	>1
58	T	C	All mutations	C	2.9912005028284097	>1
58	T	A	All mutations	A	0.9968573224387178	1
58	T	G	All mutations	G	1.9968573224387178	>1
58	T	K	All mutations	K	1.0119421747328725	1
58	T	H	All mutations	H	2.9912005028284097	>1
58	T	P	All mutations	P	1.0	1
58	T	E	All mutations	E	2.005656819610308	>1
58	T	N	All mutations	N	1.994343180389692	>1
58	T	T	All mutations	T	0.0031426775612822125	1
58	T	I	All mutations	I	1.0138277812696417	1
58	T	V	All mutations	V	1.9968573224387178	>1
58	T	Y	All mutations	Y	2.9912005028284097	>1
58	T	M	All mutations	M	1.9924575738529227	>1
58	T	Q	All mutations	Q	2.0087994971715903	>1
58	T	F	All mutations	F	2.9912005028284097	>1
58	T	R	All mutations	R	1.0119421747328725	1
59	A	T	All mutations	T	1.0	1
59	A	Y	All mutations	Y	2.8881206788183533	>1
59	A	V	All mutations	V	1.0	1
59	A	H	All mutations	H	2.8881206788183533	>1
59	A	Q	All mutations	Q	2.1118793211816467	>1
59	A	G	All mutations	G	1.0	1
59	A	A	All mutations	A	0.0	0
59	A	R	All mutations	R	2.0	>1
59	A	L	All mutations	L	2.0	>1
59	A	K	All mutations	K	2.1118793211816467	>1
59	A	C	All mutations	C	2.8881206788183533	>1
59	A	I	All mutations	I	2.1024512884978	>1
59	A	M	All mutations	M	2.8975487115022	>1
59	A	W	All mutations	W	2.8975487115022	>1
59	A	P	All mutations	P	1.0	1
59	A	F	All mutations	F	2.8881206788183533	>1
59	A	N	All mutations	N	2.8881206788183533	>1
59	A	S	All mutations	S	1.0	1
59	A	D	All mutations	D	1.8881206788183533	>1
59	A	E	All mutations	E	1.1118793211816467	>1
60	D	D	All mutations	D	0.0031426775612822125	1
60	D	R	All mutations	R	2.0	>1
60	D	I	All mutations	I	1.9993714644877436	>1
60	D	M	All mutations	M	2.996857322438718	>1
60	D	C	All mutations	C	2.001257071024513	>1
60	D	A	All mutations	A	1.0018856065367694	1
60	D	H	All mutations	H	1.0012570710245128	1
60	D	V	All mutations	V	1.0018856065367694	1
60	D	Y	All mutations	Y	1.0012570710245128	1
60	D	P	All mutations	P	2.0	>1
60	D	T	All mutations	T	1.9981143934632306	>1
60	D	L	All mutations	L	2.0	>1
60	D	N	All mutations	N	0.9993714644877436	1
60	D	F	All mutations	F	2.001257071024513	>1
60	D	G	All mutations	G	1.0018856065367694	1
60	D	K	All mutations	K	1.9968573224387178	>1
60	D	E	All mutations	E	1.0006285355122564	1
60	D	W	All mutations	W	2.998742928975487	>1
60	D	Q	All mutations	Q	1.9987429289754872	>1
60	D	S	All mutations	S	1.9981143934632306	>1
61	K	V	All mutations	V	1.9993714644877436	>1
61	K	Y	All mutations	Y	2.014456316781898	>1
61	K	M	All mutations	M	1.3475801382778128	>1
61	K	L	All mutations	L	1.9987429289754872	>1
61	K	F	All mutations	F	3.0	>1
61	K	N	All mutations	N	1.0163419233186675	1
61	K	K	All mutations	K	0.016341923318667503	1
61	K	W	All mutations	W	2.331238214959145	>1
61	K	D	All mutations	D	2.013827781269642	>1
61	K	R	All mutations	R	0.9861722187303583	1
61	K	E	All mutations	E	1.0138277812696417	1
61	K	C	All mutations	C	2.985543683218102	>1
61	K	I	All mutations	I	1.656191074795726	>1
61	K	S	All mutations	S	1.985543683218102	>1
61	K	T	All mutations	T	1.0018856065367694	1
61	K	G	All mutations	G	1.9849151477058453	>1
61	K	H	All mutations	H	2.0131992457573853	>1
61	K	A	All mutations	A	1.9993714644877436	>1
61	K	P	All mutations	P	1.9987429289754872	>1
61	K	Q	All mutations	Q	1.0131992457573853	1
62	R	I	All mutations	I	1.6115650534255186	>1
62	R	P	All mutations	P	1.671904462602137	>1
62	R	E	All mutations	E	1.9094908862350723	>1
62	R	K	All mutations	K	1.2407291011942174	>1
62	R	S	All mutations	S	1.4173475801382778	>1
62	R	T	All mutations	T	1.3299811439346323	>1
62	R	F	All mutations	F	2.9993714644877434	>1
62	R	W	All mutations	W	1.8070395977372722	>1
62	R	C	All mutations	C	2.0886235072281583	>1
62	R	V	All mutations	V	1.9987429289754872	>1
62	R	H	All mutations	H	2.5826524198617222	>1
62	R	N	All mutations	N	2.2407291011942174	>1
62	R	A	All mutations	A	1.9987429289754872	>1
62	R	M	All mutations	M	2.048397234443746	>1
62	R	G	All mutations	G	1.0879949717159019	1
62	R	Y	All mutations	Y	2.9101194217473285	>1
62	R	D	All mutations	D	2.9094908862350723	>1
62	R	L	All mutations	L	1.6712759270898805	>1
62	R	Q	All mutations	Q	1.5826524198617222	>1
62	R	R	All mutations	R	0.09113764927718417	1
63	I	G	All mutations	G	1.9956002514142048	>1
63	I	E	All mutations	E	2.0018856065367694	>1
63	I	V	All mutations	V	0.9956002514142049	1
63	I	Y	All mutations	Y	2.9937146448774357	>1
63	I	A	All mutations	A	1.9956002514142048	>1
63	I	P	All mutations	P	2.0	>1
63	I	W	All mutations	W	3.0	>1
63	I	H	All mutations	H	2.9937146448774357	>1
63	I	D	All mutations	D	2.9893148962916403	>1
63	I	Q	All mutations	Q	2.0062853551225643	>1
63	I	N	All mutations	N	1.9981143934632306	>1
63	I	L	All mutations	L	1.0	1
63	I	S	All mutations	S	1.9937146448774357	>1
63	I	C	All mutations	C	2.9937146448774357	>1
63	I	F	All mutations	F	1.9937146448774357	>1
63	I	T	All mutations	T	1.0043997485857952	1
63	I	R	All mutations	R	1.0106851037083595	1
63	I	I	All mutations	I	0.0043997485857950975	1
63	I	M	All mutations	M	1.0043997485857952	1
63	I	K	All mutations	K	1.0106851037083595	1
64	M	F	All mutations	F	2.0	>1
64	M	V	All mutations	V	0.9987429289754871	1
64	M	E	All mutations	E	1.9987429289754872	>1
64	M	S	All mutations	S	2.0	>1
64	M	Q	All mutations	Q	1.9974858579509742	>1
64	M	D	All mutations	D	2.998742928975487	>1
64	M	T	All mutations	T	1.0037712130735386	1
64	M	H	All mutations	H	2.9974858579509744	>1
64	M	A	All mutations	A	1.9987429289754872	>1
64	M	N	All mutations	N	2.003771213073539	>1
64	M	L	All mutations	L	0.9974858579509742	1
64	M	W	All mutations	W	2.0691389063482086	>1
64	M	I	All mutations	I	0.9346323067253299	1
64	M	M	All mutations	M	0.07291011942174733	1
64	M	G	All mutations	G	1.9987429289754872	>1
64	M	R	All mutations	R	1.0012570710245128	1
64	M	K	All mutations	K	1.0037712130735386	1
64	M	Y	All mutations	Y	3.0	>1
64	M	C	All mutations	C	3.0	>1
64	M	P	All mutations	P	1.9974858579509742	>1
65	E	K	All mutations	K	1.0747957259585166	1
65	E	H	All mutations	H	1.9270898805782526	>1
65	E	C	All mutations	C	2.923318667504714	>1
65	E	L	All mutations	L	2.0	>1
65	E	M	All mutations	M	2.6624764299182906	>1
65	E	I	All mutations	I	2.333752357008171	>1
65	E	N	All mutations	N	1.9252042740414834	>1
65	E	F	All mutations	F	2.925204274041483	>1
65	E	R	All mutations	R	1.9968573224387178	>1
65	E	Q	All mutations	Q	1.076681332495286	1
65	E	T	All mutations	T	1.9981143934632306	>1
65	E	S	All mutations	S	1.9993714644877436	>1
65	E	V	All mutations	V	1.0018856065367694	1
65	E	Y	All mutations	Y	1.9270898805782526	>1
65	E	G	All mutations	G	1.0	1
65	E	E	All mutations	E	0.0785669390320553	1
65	E	P	All mutations	P	2.0	>1
65	E	W	All mutations	W	2.6624764299182906	>1
65	E	A	All mutations	A	1.0018856065367694	1
65	E	D	All mutations	D	0.928975487115022	1
66	M	Q	All mutations	Q	2.0006285355122566	>1
66	M	I	All mutations	I	1.0087994971715901	1
66	M	N	All mutations	N	2.0188560653676935	>1
66	M	R	All mutations	R	1.0201131363922062	1
66	M	E	All mutations	E	1.9824010056568195	>1
66	M	K	All mutations	K	1.0201131363922062	1
66	M	F	All mutations	F	1.9981143934632306	>1
66	M	D	All mutations	D	2.9811439346323065	>1
66	M	C	All mutations	C	2.9981143934632306	>1
66	M	M	All mutations	M	0.03016970458830924	1
66	M	G	All mutations	G	1.9817724701445631	>1
66	M	T	All mutations	T	1.0194846008799496	1
66	M	Y	All mutations	Y	2.9981143934632306	>1
66	M	S	All mutations	S	1.9981143934632306	>1
66	M	H	All mutations	H	2.9993714644877434	>1
66	M	W	All mutations	W	2.0094280326838465	>1
66	M	A	All mutations	A	1.9817724701445631	>1
66	M	P	All mutations	P	2.0	>1
66	M	L	All mutations	L	0.9987429289754871	1
66	M	V	All mutations	V	0.9817724701445631	1
67	I	S	All mutations	S	1.0351979886863607	1
67	I	A	All mutations	A	1.9811439346323068	>1
67	I	K	All mutations	K	2.003142677561282	>1
67	I	H	All mutations	H	2.0163419233186675	>1
67	I	D	All mutations	D	1.9974858579509742	>1
67	I	N	All mutations	N	1.0358265241986173	1
67	I	M	All mutations	M	1.0194846008799496	1
67	I	T	All mutations	T	1.0194846008799496	1
67	I	V	All mutations	V	0.9811439346323068	1
67	I	C	All mutations	C	2.015713387806411	>1
67	I	W	All mutations	W	2.9993714644877434	>1
67	I	Q	All mutations	Q	2.9836580766813325	>1
67	I	F	All mutations	F	1.015713387806411	1
67	I	Y	All mutations	Y	2.015713387806411	>1
67	I	R	All mutations	R	1.9836580766813325	>1
67	I	P	All mutations	P	2.0	>1
67	I	G	All mutations	G	1.9811439346323068	>1
67	I	L	All mutations	L	1.0	1
67	I	E	All mutations	E	2.964802011313639	>1
67	I	I	All mutations	I	0.01948460087994972	1
68	P	W	All mutations	W	2.903205531112508	>1
68	P	D	All mutations	D	2.127592708988058	>1
68	P	E	All mutations	E	2.8711502199874293	>1
68	P	M	All mutations	M	2.903205531112508	>1
68	P	A	All mutations	A	1.0006285355122564	1
68	P	P	All mutations	P	0.0006285355122564425	1
68	P	Y	All mutations	Y	2.127592708988058	>1
68	P	K	All mutations	K	2.8711502199874293	>1
68	P	C	All mutations	C	2.128221244500314	>1
68	P	G	All mutations	G	2.0	>1
68	P	V	All mutations	V	2.0	>1
68	P	R	All mutations	R	1.0	1
68	P	T	All mutations	T	1.0006285355122564	1
68	P	S	All mutations	S	1.0006285355122564	1
68	P	I	All mutations	I	2.096794468887492	>1
68	P	N	All mutations	N	2.127592708988058	>1
68	P	Q	All mutations	Q	1.8711502199874293	>1
68	P	H	All mutations	H	1.1275927089880577	>1
68	P	F	All mutations	F	2.128221244500314	>1
68	P	L	All mutations	L	1.0	1
69	E	H	All mutations	H	2.001257071024513	>1
69	E	F	All mutations	F	2.9993714644877434	>1
69	E	P	All mutations	P	2.0	>1
69	E	A	All mutations	A	1.0006285355122564	1
69	E	N	All mutations	N	2.0006285355122566	>1
69	E	C	All mutations	C	2.9993714644877434	>1
69	E	R	All mutations	R	1.9987429289754872	>1
69	E	Y	All mutations	Y	2.001257071024513	>1
69	E	Q	All mutations	Q	1.0012570710245128	1
69	E	K	All mutations	K	1.0006285355122564	1
69	E	M	All mutations	M	2.900691389063482	>1
69	E	T	All mutations	T	1.9993714644877436	>1
69	E	G	All mutations	G	1.0	1
69	E	E	All mutations	E	0.0018856065367693275	1
69	E	D	All mutations	D	1.0018856065367694	1
69	E	W	All mutations	W	2.9013199245757386	>1
69	E	L	All mutations	L	1.9993714644877436	>1
69	E	I	All mutations	I	2.096794468887492	>1
69	E	S	All mutations	S	2.0	>1
69	E	V	All mutations	V	1.0	1
70	R	T	All mutations	T	1.0949088623507228	1
70	R	E	All mutations	E	1.9987429289754872	>1
70	R	D	All mutations	D	2.998742928975487	>1
70	R	I	All mutations	I	1.671904462602137	>1
70	R	L	All mutations	L	1.9050911376492772	>1
70	R	V	All mutations	V	2.0	>1
70	R	N	All mutations	N	2.09365179132621	>1
70	R	Y	All mutations	Y	2.998742928975487	>1
70	R	C	All mutations	C	2.001257071024513	>1
70	R	P	All mutations	P	1.9050911376492772	>1
70	R	H	All mutations	H	2.903834066624764	>1
70	R	W	All mutations	W	1.4242614707730987	>1
70	R	F	All mutations	F	3.0	>1
70	R	M	All mutations	M	1.5179132620993085	>1
70	R	R	All mutations	R	0.001257071024512885	1
70	R	S	All mutations	S	1.0961659333752356	1
70	R	A	All mutations	A	2.0	>1
70	R	Q	All mutations	Q	1.9038340666247644	>1
70	R	K	All mutations	K	1.0936517913262098	1
70	R	G	All mutations	G	1.0012570710245128	1
71	N	E	All mutations	E	1.9987429289754872	>1
71	N	W	All mutations	W	3.0	>1
71	N	D	All mutations	D	1.0	1
71	N	I	All mutations	I	1.0006285355122564	1
71	N	H	All mutations	H	1.0006285355122564	1
71	N	L	All mutations	L	2.0	>1
71	N	P	All mutations	P	2.0	>1
71	N	N	All mutations	N	0.001257071024512885	1
71	N	R	All mutations	R	2.0	>1
71	N	G	All mutations	G	1.9993714644877436	>1
71	N	Q	All mutations	Q	1.9993714644877436	>1
71	N	V	All mutations	V	1.9993714644877436	>1
71	N	C	All mutations	C	2.0006285355122566	>1
71	N	Y	All mutations	Y	1.0006285355122564	1
71	N	A	All mutations	A	1.9993714644877436	>1
71	N	T	All mutations	T	1.0006285355122564	1
71	N	S	All mutations	S	1.0006285355122564	1
71	N	F	All mutations	F	2.0006285355122566	>1
71	N	K	All mutations	K	1.0	1
71	N	M	All mutations	M	2.0006285355122566	>1
72	E	V	All mutations	V	1.0006285355122564	1
72	E	Y	All mutations	Y	2.0006285355122566	>1
72	E	G	All mutations	G	1.0	1
72	E	H	All mutations	H	2.0	>1
72	E	N	All mutations	N	2.0006285355122566	>1
72	E	T	All mutations	T	2.0	>1
72	E	P	All mutations	P	1.9993714644877436	>1
72	E	S	All mutations	S	2.0	>1
72	E	W	All mutations	W	2.7410433689503457	>1
72	E	F	All mutations	F	3.0	>1
72	E	L	All mutations	L	1.9993714644877436	>1
72	E	A	All mutations	A	1.0006285355122564	1
72	E	C	All mutations	C	2.9993714644877434	>1
72	E	K	All mutations	K	1.0006285355122564	1
72	E	M	All mutations	M	2.7416719044626023	>1
72	E	Q	All mutations	Q	1.0	1
72	E	R	All mutations	R	1.9987429289754872	>1
72	E	D	All mutations	D	1.0012570710245128	1
72	E	I	All mutations	I	2.2583280955373977	>1
72	E	E	All mutations	E	0.001257071024512885	1
73	Q	A	All mutations	A	2.0	>1
73	Q	P	All mutations	P	1.0012570710245128	1
73	Q	R	All mutations	R	1.0	1
73	Q	S	All mutations	S	2.0	>1
73	Q	L	All mutations	L	1.0012570710245128	1
73	Q	F	All mutations	F	2.996857322438718	>1
73	Q	K	All mutations	K	1.0018856065367694	1
73	Q	H	All mutations	H	0.9981143934632307	1
73	Q	V	All mutations	V	2.0	>1
73	Q	I	All mutations	I	2.1301068510370835	>1
73	Q	M	All mutations	M	2.8673790069138905	>1
73	Q	D	All mutations	D	1.9968573224387178	>1
73	Q	C	All mutations	C	2.996857322438718	>1
73	Q	Y	All mutations	Y	1.9968573224387178	>1
73	Q	Q	All mutations	Q	0.0043997485857950975	1
73	Q	T	All mutations	T	1.9987429289754872	>1
73	Q	W	All mutations	W	2.8686360779384037	>1
73	Q	G	All mutations	G	2.0	>1
73	Q	E	All mutations	E	1.0031426775612822	1
73	Q	N	All mutations	N	1.9956002514142048	>1
74	G	S	All mutations	S	1.5556253928346953	>1
74	G	R	All mutations	R	1.0006285355122564	1
74	G	G	All mutations	G	0.0006285355122564425	1
74	G	N	All mutations	N	2.554996857322439	>1
74	G	V	All mutations	V	1.0	1
74	G	H	All mutations	H	2.554996857322439	>1
74	G	Q	All mutations	Q	2.4437460716530484	>1
74	G	L	All mutations	L	2.0	>1
74	G	A	All mutations	A	1.0	1
74	G	M	All mutations	M	2.583909490886235	>1
74	G	K	All mutations	K	2.4437460716530484	>1
74	G	I	All mutations	I	2.416090509113765	>1
74	G	P	All mutations	P	2.0	>1
74	G	F	All mutations	F	2.555625392834695	>1
74	G	C	All mutations	C	1.5562539283469516	>1
74	G	Y	All mutations	Y	2.554996857322439	>1
74	G	W	All mutations	W	1.5845380263984916	>1
74	G	T	All mutations	T	2.0	>1
74	G	E	All mutations	E	1.4437460716530484	>1
74	G	D	All mutations	D	1.5549968573224386	>1
75	Q	M	All mutations	M	2.5505971087366435	>1
75	Q	K	All mutations	K	1.0006285355122564	1
75	Q	N	All mutations	N	1.9993714644877436	>1
75	Q	Y	All mutations	Y	1.9993714644877436	>1
75	Q	H	All mutations	H	1.0012570710245128	1
75	Q	A	All mutations	A	2.0	>1
75	Q	D	All mutations	D	2.0	>1
75	Q	Q	All mutations	Q	0.00251414204902577	1
75	Q	W	All mutations	W	2.5499685732243873	>1
75	Q	C	All mutations	C	2.9981143934632306	>1
75	Q	P	All mutations	P	1.0012570710245128	1
75	Q	T	All mutations	T	1.9993714644877436	>1
75	Q	I	All mutations	I	2.4481458202388433	>1
75	Q	L	All mutations	L	1.0006285355122564	1
75	Q	E	All mutations	E	1.0012570710245128	1
75	Q	R	All mutations	R	1.0	1
75	Q	S	All mutations	S	1.9993714644877436	>1
75	Q	G	All mutations	G	1.9993714644877436	>1
75	Q	F	All mutations	F	2.998742928975487	>1
75	Q	V	All mutations	V	2.0	>1
76	T	Y	All mutations	Y	2.199245757385292	>1
76	T	C	All mutations	C	2.2042740414833437	>1
76	T	E	All mutations	E	2.7850408548082966	>1
76	T	K	All mutations	K	1.7963544940289127	>1
76	T	P	All mutations	P	1.027027027027027	1
76	T	H	All mutations	H	2.199245757385292	>1
76	T	T	All mutations	T	0.03268384663733501	1
76	T	Q	All mutations	Q	2.7906976744186047	>1
76	T	L	All mutations	L	1.9780012570710246	>1
76	T	V	All mutations	V	1.9723444374607166	>1
76	T	G	All mutations	G	1.994343180389692	>1
76	T	A	All mutations	A	1.021370207416719	1
76	T	D	All mutations	D	2.1935889377749844	>1
76	T	F	All mutations	F	2.1822752985543685	>1
76	T	M	All mutations	M	1.8617221873035827	>1
76	T	R	All mutations	R	1.7963544940289127	>1
76	T	S	All mutations	S	1.0037712130735386	1
76	T	N	All mutations	N	1.2049025769956003	>1
76	T	I	All mutations	I	1.1055939660590823	>1
76	T	W	All mutations	W	2.87806411062225	>1
77	L	E	All mutations	E	2.9692017598994345	>1
77	L	K	All mutations	K	2.9692017598994345	>1
77	L	T	All mutations	T	2.0	>1
77	L	I	All mutations	I	1.0100565681961031	1
77	L	M	All mutations	M	1.9899434318038969	>1
77	L	D	All mutations	D	2.0307982401005655	>1
77	L	L	All mutations	L	0.0	0
77	L	C	All mutations	C	2.0307982401005655	>1
77	L	V	All mutations	V	1.0	1
77	L	H	All mutations	H	1.0307982401005658	1
77	L	A	All mutations	A	2.0	>1
77	L	F	All mutations	F	1.0307982401005658	1
77	L	P	All mutations	P	1.0	1
77	L	R	All mutations	R	1.0	1
77	L	N	All mutations	N	2.0307982401005655	>1
77	L	Y	All mutations	Y	2.0307982401005655	>1
77	L	G	All mutations	G	2.0	>1
77	L	Q	All mutations	Q	1.9692017598994342	>1
77	L	S	All mutations	S	2.0	>1
77	L	W	All mutations	W	2.989943431803897	>1
78	W	T	All mutations	T	2.0	>1
78	W	F	All mutations	F	2.0	>1
78	W	V	All mutations	V	2.0	>1
78	W	K	All mutations	K	2.0	>1
78	W	I	All mutations	I	3.0	>1
78	W	E	All mutations	E	2.0	>1
78	W	D	All mutations	D	3.0	>1
78	W	H	All mutations	H	3.0	>1
78	W	L	All mutations	L	1.0	1
78	W	A	All mutations	A	2.0	>1
78	W	P	All mutations	P	2.0	>1
78	W	R	All mutations	R	1.0	1
78	W	N	All mutations	N	3.0	>1
78	W	G	All mutations	G	1.0	1
78	W	Q	All mutations	Q	2.0	>1
78	W	C	All mutations	C	1.0	1
78	W	S	All mutations	S	1.0	1
78	W	Y	All mutations	Y	2.0	>1
78	W	M	All mutations	M	2.0	>1
78	W	W	All mutations	W	0.0	0
79	S	K	All mutations	K	2.0006285355122566	>1
79	S	F	All mutations	F	1.9993714644877436	>1
79	S	R	All mutations	R	1.0050282840980516	1
79	S	A	All mutations	A	1.9949717159019484	>1
79	S	D	All mutations	D	1.9981143934632306	>1
79	S	N	All mutations	N	1.0006285355122564	1
79	S	G	All mutations	G	1.0037712130735386	1
79	S	I	All mutations	I	1.0006285355122564	1
79	S	E	All mutations	E	2.9981143934632306	>1
79	S	C	All mutations	C	1.0050282840980516	1
79	S	W	All mutations	W	2.0050282840980516	>1
79	S	T	All mutations	T	0.9974858579509742	1
79	S	P	All mutations	P	1.9962287869264614	>1
79	S	M	All mutations	M	2.0006285355122566	>1
79	S	L	All mutations	L	1.9993714644877436	>1
79	S	H	All mutations	H	1.9993714644877436	>1
79	S	S	All mutations	S	0.006285355122564425	1
79	S	Y	All mutations	Y	1.9993714644877436	>1
79	S	V	All mutations	V	1.9981143934632306	>1
79	S	Q	All mutations	Q	2.9993714644877434	>1
80	K	V	All mutations	V	2.0	>1
80	K	N	All mutations	N	1.0094280326838467	1
80	K	L	All mutations	L	2.0	>1
80	K	E	All mutations	E	1.0106851037083595	1
80	K	T	All mutations	T	1.0	1
80	K	I	All mutations	I	1.4192331866750472	>1
80	K	G	All mutations	G	1.9899434318038969	>1
80	K	C	All mutations	C	2.9893148962916403	>1
80	K	W	All mutations	W	2.5707102451288497	>1
80	K	Y	All mutations	Y	2.0094280326838465	>1
80	K	A	All mutations	A	2.0	>1
80	K	P	All mutations	P	2.0	>1
80	K	S	All mutations	S	1.9893148962916405	>1
80	K	H	All mutations	H	2.0094280326838465	>1
80	K	D	All mutations	D	2.0094280326838465	>1
80	K	M	All mutations	M	1.5807668133249528	>1
80	K	R	All mutations	R	0.9905719673161534	1
80	K	Q	All mutations	Q	1.0106851037083595	1
80	K	F	All mutations	F	2.9993714644877434	>1
80	K	K	All mutations	K	0.010685103708359522	1
81	T	E	All mutations	E	2.016970458830924	>1
81	T	R	All mutations	R	1.0238843494657448	1
81	T	C	All mutations	C	2.9792583280955376	>1
81	T	W	All mutations	W	2.9635449402891263	>1
81	T	L	All mutations	L	1.985543683218102	>1
81	T	F	All mutations	F	2.9654305468258957	>1
81	T	T	All mutations	T	0.01759899434318039	1
81	T	K	All mutations	K	1.0238843494657448	1
81	T	S	All mutations	S	1.0031426775612822	1
81	T	G	All mutations	G	1.9968573224387178	>1
81	T	A	All mutations	A	1.0106851037083595	1
81	T	V	All mutations	V	1.9830295411690761	>1
81	T	N	All mutations	N	1.9836580766813325	>1
81	T	Q	All mutations	Q	2.0201131363922062	>1
81	T	P	All mutations	P	1.0138277812696417	1
81	T	M	All mutations	M	1.9541169076052798	>1
81	T	D	All mutations	D	2.9767441860465116	>1
81	T	H	All mutations	H	2.9798868636077938	>1
81	T	I	All mutations	I	1.0257699560025142	1
81	T	Y	All mutations	Y	2.9792583280955376	>1
82	N	I	All mutations	I	0.9993714644877436	1
82	N	R	All mutations	R	1.9868007542426147	>1
82	N	G	All mutations	G	1.987429289754871	>1
82	N	M	All mutations	M	1.9993714644877436	>1
82	N	E	All mutations	E	2.0125707102451287	>1
82	N	W	All mutations	W	2.9880578252671275	>1
82	N	P	All mutations	P	1.9987429289754872	>1
82	N	Q	All mutations	Q	2.0131992457573853	>1
82	N	L	All mutations	L	1.9987429289754872	>1
82	N	D	All mutations	D	1.0150848522941547	1
82	N	H	All mutations	H	1.015713387806411	1
82	N	A	All mutations	A	1.9981143934632306	>1
82	N	N	All mutations	N	0.016341923318667503	1
82	N	Y	All mutations	Y	1.015713387806411	1
82	N	S	All mutations	S	0.9899434318038969	1
82	N	V	All mutations	V	1.9981143934632306	>1
82	N	K	All mutations	K	1.0138277812696417	1
82	N	F	All mutations	F	2.0	>1
82	N	C	All mutations	C	1.9893148962916405	>1
82	N	T	All mutations	T	0.9993714644877436	1
83	D	V	All mutations	V	1.0006285355122564	1
83	D	E	All mutations	E	1.0006285355122564	1
83	D	G	All mutations	G	1.0006285355122564	1
83	D	S	All mutations	S	2.0	>1
83	D	R	All mutations	R	1.9993714644877436	>1
83	D	H	All mutations	H	0.9993714644877436	1
83	D	C	All mutations	C	2.0	>1
83	D	P	All mutations	P	1.9993714644877436	>1
83	D	A	All mutations	A	1.0006285355122564	1
83	D	Y	All mutations	Y	1.0	1
83	D	I	All mutations	I	2.0	>1
83	D	W	All mutations	W	3.0	>1
83	D	T	All mutations	T	2.0	>1
83	D	K	All mutations	K	2.0	>1
83	D	Q	All mutations	Q	1.9993714644877436	>1
83	D	D	All mutations	D	0.0006285355122564425	1
83	D	N	All mutations	N	1.0	1
83	D	L	All mutations	L	1.9993714644877436	>1
83	D	F	All mutations	F	2.0	>1
83	D	M	All mutations	M	3.0	>1
84	A	M	All mutations	M	2.9981143934632306	>1
84	A	F	All mutations	F	2.021370207416719	>1
84	A	Q	All mutations	Q	2.977372721558768	>1
84	A	Y	All mutations	Y	2.021370207416719	>1
84	A	V	All mutations	V	0.9993714644877436	1
84	A	R	All mutations	R	2.0	>1
84	A	I	All mutations	I	2.0006285355122566	>1
84	A	L	All mutations	L	1.9993714644877436	>1
84	A	P	All mutations	P	1.0012570710245128	1
84	A	C	All mutations	C	2.0219987429289756	>1
84	A	A	All mutations	A	0.001257071024512885	1
84	A	E	All mutations	E	1.977372721558768	>1
84	A	W	All mutations	W	2.998742928975487	>1
84	A	K	All mutations	K	2.977372721558768	>1
84	A	N	All mutations	N	2.021370207416719	>1
84	A	H	All mutations	H	2.021370207416719	>1
84	A	D	All mutations	D	1.021370207416719	1
84	A	T	All mutations	T	1.0012570710245128	1
84	A	G	All mutations	G	1.0	1
84	A	S	All mutations	S	1.0012570710245128	1
85	G	P	All mutations	P	2.0	>1
85	G	Q	All mutations	Q	2.1401634192331866	>1
85	G	A	All mutations	A	1.0006285355122564	1
85	G	T	All mutations	T	1.9993714644877436	>1
85	G	R	All mutations	R	0.9993714644877436	1
85	G	I	All mutations	I	2.146448774355751	>1
85	G	E	All mutations	E	1.140791954745443	>1
85	G	F	All mutations	F	2.8598365807668134	>1
85	G	N	All mutations	N	2.8592080452545567	>1
85	G	C	All mutations	C	1.8598365807668134	>1
85	G	K	All mutations	K	2.13953488372093	>1
85	G	W	All mutations	W	1.8529226901319924	>1
85	G	L	All mutations	L	2.0	>1
85	G	M	All mutations	M	2.8522941546197362	>1
85	G	G	All mutations	G	0.0006285355122564425	1
85	G	H	All mutations	H	2.8598365807668134	>1
85	G	D	All mutations	D	1.8604651162790697	>1
85	G	Y	All mutations	Y	2.8598365807668134	>1
85	G	S	All mutations	S	1.859208045254557	>1
85	G	V	All mutations	V	1.0006285355122564	1
86	S	H	All mutations	H	2.9798868636077938	>1
86	S	R	All mutations	R	2.0	>1
86	S	N	All mutations	N	2.9798868636077938	>1
86	S	K	All mutations	K	2.0201131363922062	>1
86	S	Y	All mutations	Y	1.9798868636077938	>1
86	S	C	All mutations	C	1.9798868636077938	>1
86	S	V	All mutations	V	2.0	>1
86	S	L	All mutations	L	1.0201131363922062	1
86	S	G	All mutations	G	2.0	>1
86	S	M	All mutations	M	2.8981772470144564	>1
86	S	W	All mutations	W	1.8981772470144562	>1
86	S	S	All mutations	S	0.0	0
86	S	D	All mutations	D	2.9798868636077938	>1
86	S	E	All mutations	E	2.0201131363922062	>1
86	S	Q	All mutations	Q	2.0201131363922062	>1
86	S	I	All mutations	I	2.1018227529855436	>1
86	S	F	All mutations	F	1.9798868636077938	>1
86	S	P	All mutations	P	1.0	1
86	S	A	All mutations	A	1.0	1
86	S	T	All mutations	T	1.0	1
87	D	G	All mutations	G	1.0006285355122564	1
87	D	M	All mutations	M	2.998742928975487	>1
87	D	Y	All mutations	Y	1.0006285355122564	1
87	D	N	All mutations	N	0.9993714644877436	1
87	D	F	All mutations	F	2.0	>1
87	D	L	All mutations	L	2.0	>1
87	D	K	All mutations	K	1.9993714644877436	>1
87	D	C	All mutations	C	1.9993714644877436	>1
87	D	T	All mutations	T	1.9987429289754872	>1
87	D	P	All mutations	P	2.0	>1
87	D	A	All mutations	A	1.0012570710245128	1
87	D	W	All mutations	W	2.9993714644877434	>1
87	D	E	All mutations	E	1.0018856065367694	1
87	D	I	All mutations	I	1.9987429289754872	>1
87	D	H	All mutations	H	1.0006285355122564	1
87	D	S	All mutations	S	1.9981143934632306	>1
87	D	V	All mutations	V	1.0012570710245128	1
87	D	R	All mutations	R	1.9993714644877436	>1
87	D	D	All mutations	D	0.0018856065367693275	1
87	D	Q	All mutations	Q	2.0006285355122566	>1
88	R	T	All mutations	T	1.453174104336895	>1
88	R	L	All mutations	L	1.5436832181018227	>1
88	R	F	All mutations	F	2.996228786926461	>1
88	R	H	All mutations	H	2.541169076052797	>1
88	R	K	All mutations	K	1.4487743557511	>1
88	R	E	All mutations	E	1.9956002514142048	>1
88	R	G	All mutations	G	1.0081709616593337	1
88	R	Q	All mutations	Q	1.54242614707731	>1
88	R	S	All mutations	S	1.45757385292269	>1
88	R	V	All mutations	V	1.9968573224387178	>1
88	R	W	All mutations	W	1.8472658705216844	>1
88	R	D	All mutations	D	2.994343180389692	>1
88	R	R	All mutations	R	0.008170961659333752	1
88	R	I	All mutations	I	1.6109365179132622	>1
88	R	M	All mutations	M	2.2891263356379636	>1
88	R	Y	All mutations	Y	2.994343180389692	>1
88	R	A	All mutations	A	2.0	>1
88	R	P	All mutations	P	1.546825895663105	>1
88	R	N	All mutations	N	2.447517284726587	>1
88	R	C	All mutations	C	2.007542426147077	>1
89	V	N	All mutations	N	2.974858579509742	>1
89	V	K	All mutations	K	1.9987429289754872	>1
89	V	P	All mutations	P	2.0	>1
89	V	S	All mutations	S	1.9993714644877436	>1
89	V	V	All mutations	V	0.013827781269641735	1
89	V	F	All mutations	F	1.987429289754871	>1
89	V	R	All mutations	R	1.9868007542426147	>1
89	V	L	All mutations	L	0.9993714644877436	1
89	V	T	All mutations	T	1.9868007542426147	>1
89	V	W	All mutations	W	2.1615336266499057	>1
89	V	G	All mutations	G	1.0138277812696417	1
89	V	C	All mutations	C	2.9874292897548713	>1
89	V	D	All mutations	D	2.0018856065367694	>1
89	V	E	All mutations	E	1.0257699560025142	1
89	V	Y	All mutations	Y	2.9874292897548713	>1
89	V	A	All mutations	A	1.0138277812696417	1
89	V	I	All mutations	I	1.8246385920804526	>1
89	V	Q	All mutations	Q	2.0119421747328725	>1
89	V	M	All mutations	M	1.1489629164047768	>1
89	V	H	All mutations	H	2.9880578252671275	>1
90	M	F	All mutations	F	2.0	>1
90	M	V	All mutations	V	0.9993714644877436	1
90	M	E	All mutations	E	1.9993714644877436	>1
90	M	L	All mutations	L	1.0	1
90	M	S	All mutations	S	2.0	>1
90	M	D	All mutations	D	2.9993714644877434	>1
90	M	P	All mutations	P	2.0	>1
90	M	T	All mutations	T	1.0006285355122564	1
90	M	A	All mutations	A	1.9993714644877436	>1
90	M	Y	All mutations	Y	3.0	>1
90	M	G	All mutations	G	1.9993714644877436	>1
90	M	W	All mutations	W	2.003142677561282	>1
90	M	C	All mutations	C	3.0	>1
90	M	I	All mutations	I	0.9974858579509742	1
90	M	H	All mutations	H	3.0	>1
90	M	R	All mutations	R	1.0006285355122564	1
90	M	N	All mutations	N	2.0006285355122566	>1
90	M	K	All mutations	K	1.0006285355122564	1
90	M	M	All mutations	M	0.003771213073538655	1
90	M	Q	All mutations	Q	2.0	>1
91	V	H	All mutations	H	2.998742928975487	>1
91	V	Y	All mutations	Y	2.998742928975487	>1
91	V	Q	All mutations	Q	2.001257071024513	>1
91	V	M	All mutations	M	1.5688246385920805	>1
91	V	V	All mutations	V	0.001257071024512885	1
91	V	C	All mutations	C	2.998742928975487	>1
91	V	D	All mutations	D	2.0	>1
91	V	R	All mutations	R	1.9987429289754872	>1
91	V	I	All mutations	I	1.4286612193588937	>1
91	V	K	All mutations	K	2.0	>1
91	V	N	All mutations	N	2.9974858579509744	>1
91	V	G	All mutations	G	1.0012570710245128	1
91	V	S	All mutations	S	2.0	>1
91	V	W	All mutations	W	2.5700817096165935	>1
91	V	T	All mutations	T	1.9987429289754872	>1
91	V	F	All mutations	F	1.9987429289754872	>1
91	V	A	All mutations	A	1.0012570710245128	1
91	V	P	All mutations	P	2.0	>1
91	V	L	All mutations	L	1.0	1
91	V	E	All mutations	E	1.0025141420490258	1
92	S	S	All mutations	S	0.0	0
92	S	P	All mutations	P	1.0	1
92	S	A	All mutations	A	1.0	1
92	S	V	All mutations	V	2.0	>1
92	S	I	All mutations	I	2.0364550597108737	>1
92	S	R	All mutations	R	2.0	>1
92	S	Q	All mutations	Q	2.186046511627907	>1
92	S	D	All mutations	D	2.813953488372093	>1
92	S	C	All mutations	C	1.813953488372093	>1
92	S	M	All mutations	M	2.9635449402891263	>1
92	S	N	All mutations	N	2.813953488372093	>1
92	S	K	All mutations	K	2.186046511627907	>1
92	S	L	All mutations	L	1.186046511627907	>1
92	S	F	All mutations	F	1.813953488372093	>1
92	S	E	All mutations	E	2.186046511627907	>1
92	S	T	All mutations	T	1.0	1
92	S	W	All mutations	W	1.9635449402891263	>1
92	S	G	All mutations	G	2.0	>1
92	S	H	All mutations	H	2.813953488372093	>1
92	S	Y	All mutations	Y	1.813953488372093	>1
93	P	M	All mutations	M	2.998742928975487	>1
93	P	S	All mutations	S	0.9993714644877436	1
93	P	I	All mutations	I	2.001257071024513	>1
93	P	K	All mutations	K	2.9874292897548713	>1
93	P	G	All mutations	G	2.0	>1
93	P	W	All mutations	W	2.9981143934632306	>1
93	P	T	All mutations	T	1.0	1
93	P	N	All mutations	N	2.0125707102451287	>1
93	P	R	All mutations	R	1.0006285355122564	1
93	P	D	All mutations	D	2.0125707102451287	>1
93	P	E	All mutations	E	2.9874292897548713	>1
93	P	P	All mutations	P	0.0006285355122564425	1
93	P	V	All mutations	V	2.0	>1
93	P	Q	All mutations	Q	1.9880578252671275	>1
93	P	F	All mutations	F	2.0119421747328725	>1
93	P	H	All mutations	H	1.0131992457573853	1
93	P	A	All mutations	A	1.0	1
93	P	C	All mutations	C	2.0119421747328725	>1
93	P	L	All mutations	L	1.0006285355122564	1
93	P	Y	All mutations	Y	2.0119421747328725	>1
94	L	C	All mutations	C	2.974230043997486	>1
94	L	H	All mutations	H	1.9993714644877436	>1
94	L	I	All mutations	I	1.768698931489629	>1
94	L	S	All mutations	S	1.987429289754871	>1
94	L	K	All mutations	K	2.0131992457573853	>1
94	L	R	All mutations	R	1.012570710245129	1
94	L	D	All mutations	D	2.9868007542426147	>1
94	L	Q	All mutations	Q	1.0257699560025142	1
94	L	W	All mutations	W	2.218730358265242	>1
94	L	M	All mutations	M	1.231301068510371	>1
94	L	N	All mutations	N	2.9868007542426147	>1
94	L	T	All mutations	T	2.0	>1
94	L	G	All mutations	G	2.0	>1
94	L	P	All mutations	P	1.012570710245129	1
94	L	V	All mutations	V	1.0	1
94	L	E	All mutations	E	2.0131992457573853	>1
94	L	F	All mutations	F	1.9742300439974858	>1
94	L	Y	All mutations	Y	2.974230043997486	>1
94	L	L	All mutations	L	0.0	0
94	L	A	All mutations	A	2.0	>1
95	A	D	All mutations	D	1.033940917661848	1
95	A	R	All mutations	R	2.0	>1
95	A	W	All mutations	W	2.9780012570710244	>1
95	A	Q	All mutations	Q	2.9660590823381523	>1
95	A	P	All mutations	P	1.0006285355122564	1
95	A	Y	All mutations	Y	2.0339409176618477	>1
95	A	K	All mutations	K	2.9660590823381523	>1
95	A	C	All mutations	C	2.0339409176618477	>1
95	A	A	All mutations	A	0.0006285355122564425	1
95	A	V	All mutations	V	0.9993714644877436	1
95	A	S	All mutations	S	1.0006285355122564	1
95	A	L	All mutations	L	1.9993714644877436	>1
95	A	M	All mutations	M	2.977372721558768	>1
95	A	I	All mutations	I	2.021370207416719	>1
95	A	E	All mutations	E	1.966059082338152	>1
95	A	T	All mutations	T	1.0006285355122564	1
95	A	H	All mutations	H	2.0339409176618477	>1
95	A	F	All mutations	F	2.0333123821495915	>1
95	A	N	All mutations	N	2.0339409176618477	>1
95	A	G	All mutations	G	1.0	1
96	V	V	All mutations	V	0.0006285355122564425	1
96	V	S	All mutations	S	2.0	>1
96	V	C	All mutations	C	3.0	>1
96	V	D	All mutations	D	2.0006285355122566	>1
96	V	E	All mutations	E	1.0006285355122564	1
96	V	H	All mutations	H	3.0	>1
96	V	W	All mutations	W	2.2294154619736015	>1
96	V	F	All mutations	F	2.0	>1
96	V	Y	All mutations	Y	3.0	>1
96	V	A	All mutations	A	1.0006285355122564	1
96	V	M	All mutations	M	1.2287869264613451	>1
96	V	K	All mutations	K	1.9993714644877436	>1
96	V	T	All mutations	T	1.9993714644877436	>1
96	V	Q	All mutations	Q	2.0	>1
96	V	R	All mutations	R	1.9993714644877436	>1
96	V	G	All mutations	G	1.0006285355122564	1
96	V	N	All mutations	N	2.9993714644877434	>1
96	V	L	All mutations	L	1.0	1
96	V	I	All mutations	I	1.769956002514142	>1
96	V	P	All mutations	P	2.0	>1
97	T	V	All mutations	V	2.0	>1
97	T	L	All mutations	L	2.0	>1
97	T	M	All mutations	M	1.7919547454431175	>1
97	T	C	All mutations	C	2.7322438717787554	>1
97	T	F	All mutations	F	2.7322438717787554	>1
97	T	Q	All mutations	Q	2.2677561282212446	>1
97	T	A	All mutations	A	1.0	1
97	T	P	All mutations	P	1.0	1
97	T	N	All mutations	N	1.7322438717787556	>1
97	T	E	All mutations	E	2.2677561282212446	>1
97	T	Y	All mutations	Y	2.7322438717787554	>1
97	T	K	All mutations	K	1.2677561282212444	>1
97	T	R	All mutations	R	1.2677561282212444	>1
97	T	T	All mutations	T	0.0	0
97	T	S	All mutations	S	1.0	1
97	T	H	All mutations	H	2.7322438717787554	>1
97	T	W	All mutations	W	2.7919547454431175	>1
97	T	G	All mutations	G	2.0	>1
97	T	D	All mutations	D	2.7322438717787554	>1
97	T	I	All mutations	I	1.2080452545568825	>1
98	W	G	All mutations	G	1.0	1
98	W	T	All mutations	T	2.0	>1
98	W	E	All mutations	E	2.0	>1
98	W	C	All mutations	C	1.0	1
98	W	F	All mutations	F	2.0	>1
98	W	K	All mutations	K	2.0	>1
98	W	W	All mutations	W	0.0	0
98	W	Q	All mutations	Q	2.0	>1
98	W	H	All mutations	H	3.0	>1
98	W	L	All mutations	L	1.0	1
98	W	A	All mutations	A	2.0	>1
98	W	D	All mutations	D	3.0	>1
98	W	S	All mutations	S	1.0	1
98	W	V	All mutations	V	2.0	>1
98	W	R	All mutations	R	1.0	1
98	W	P	All mutations	P	2.0	>1
98	W	N	All mutations	N	3.0	>1
98	W	M	All mutations	M	2.0	>1
98	W	Y	All mutations	Y	2.0	>1
98	W	I	All mutations	I	3.0	>1
99	W	R	All mutations	R	1.0	1
99	W	S	All mutations	S	1.0006285355122564	1
99	W	G	All mutations	G	0.9993714644877436	1
99	W	C	All mutations	C	1.0006285355122564	1
99	W	K	All mutations	K	2.0	>1
99	W	W	All mutations	W	0.001257071024512885	1
99	W	M	All mutations	M	2.0006285355122566	>1
99	W	I	All mutations	I	2.9993714644877434	>1
99	W	T	All mutations	T	2.0	>1
99	W	Y	All mutations	Y	2.0006285355122566	>1
99	W	A	All mutations	A	1.9993714644877436	>1
99	W	D	All mutations	D	2.9993714644877434	>1
99	W	E	All mutations	E	1.9993714644877436	>1
99	W	V	All mutations	V	1.9993714644877436	>1
99	W	F	All mutations	F	2.0006285355122566	>1
99	W	Q	All mutations	Q	2.0	>1
99	W	P	All mutations	P	2.0	>1
99	W	N	All mutations	N	3.0	>1
99	W	H	All mutations	H	3.0	>1
99	W	L	All mutations	L	1.0006285355122564	1
100	N	D	All mutations	D	1.0	1
100	N	E	All mutations	E	2.0	>1
100	N	F	All mutations	F	2.0	>1
100	N	Y	All mutations	Y	1.0	1
100	N	N	All mutations	N	0.0	0
100	N	K	All mutations	K	1.0	1
100	N	V	All mutations	V	2.0	>1
100	N	S	All mutations	S	1.0	1
100	N	W	All mutations	W	3.0	>1
100	N	Q	All mutations	Q	2.0	>1
100	N	T	All mutations	T	1.0	1
100	N	G	All mutations	G	2.0	>1
100	N	I	All mutations	I	1.0	1
100	N	M	All mutations	M	2.0	>1
100	N	L	All mutations	L	2.0	>1
100	N	R	All mutations	R	2.0	>1
100	N	H	All mutations	H	1.0	1
100	N	C	All mutations	C	2.0	>1
100	N	A	All mutations	A	2.0	>1
100	N	P	All mutations	P	2.0	>1
101	R	K	All mutations	K	1.0006285355122564	1
101	R	V	All mutations	V	2.0	>1
101	R	F	All mutations	F	3.0	>1
101	R	S	All mutations	S	1.0018856065367694	1
101	R	Y	All mutations	Y	2.9993714644877434	>1
101	R	Q	All mutations	Q	1.9981143934632306	>1
101	R	L	All mutations	L	1.9987429289754872	>1
101	R	R	All mutations	R	0.0006285355122564425	1
101	R	D	All mutations	D	2.9993714644877434	>1
101	R	I	All mutations	I	1.6140791954745444	>1
101	R	T	All mutations	T	1.0012570710245128	1
101	R	P	All mutations	P	1.9987429289754872	>1
101	R	A	All mutations	A	2.0	>1
101	R	N	All mutations	N	2.0006285355122566	>1
101	R	W	All mutations	W	1.387806411062225	>1
101	R	H	All mutations	H	2.9981143934632306	>1
101	R	E	All mutations	E	1.9993714644877436	>1
101	R	C	All mutations	C	2.0006285355122566	>1
101	R	G	All mutations	G	1.0006285355122564	1
101	R	M	All mutations	M	1.3884349465744814	>1
102	N	H	All mutations	H	1.015713387806411	1
102	N	K	All mutations	K	1.0094280326838467	1
102	N	R	All mutations	R	1.9849151477058453	>1
102	N	M	All mutations	M	1.9993714644877436	>1
102	N	L	All mutations	L	1.9993714644877436	>1
102	N	G	All mutations	G	1.9880578252671275	>1
102	N	C	All mutations	C	1.9912005028284099	>1
102	N	P	All mutations	P	2.0	>1
102	N	N	All mutations	N	0.01571338780641106	1
102	N	W	All mutations	W	2.9880578252671275	>1
102	N	A	All mutations	A	2.0	>1
102	N	Q	All mutations	Q	2.0094280326838465	>1
102	N	Y	All mutations	Y	1.015713387806411	1
102	N	E	All mutations	E	2.0094280326838465	>1
102	N	D	All mutations	D	1.015713387806411	1
102	N	F	All mutations	F	2.0025141420490256	>1
102	N	I	All mutations	I	0.9993714644877436	1
102	N	S	All mutations	S	0.9912005028284098	1
102	N	T	All mutations	T	1.0	1
102	N	V	All mutations	V	1.9993714644877436	>1
103	G	K	All mutations	K	2.0050282840980516	>1
103	G	A	All mutations	A	1.0	1
103	G	H	All mutations	H	2.9949717159019484	>1
103	G	Q	All mutations	Q	2.0050282840980516	>1
103	G	W	All mutations	W	1.698931489629164	>1
103	G	P	All mutations	P	2.0	>1
103	G	I	All mutations	I	2.301068510370836	>1
103	G	C	All mutations	C	1.9949717159019484	>1
103	G	G	All mutations	G	0.0	0
103	G	V	All mutations	V	1.0	1
103	G	L	All mutations	L	2.0	>1
103	G	D	All mutations	D	1.9949717159019484	>1
103	G	M	All mutations	M	2.698931489629164	>1
103	G	R	All mutations	R	1.0	1
103	G	S	All mutations	S	1.9949717159019484	>1
103	G	N	All mutations	N	2.9949717159019484	>1
103	G	E	All mutations	E	1.0050282840980516	1
103	G	F	All mutations	F	2.9949717159019484	>1
103	G	Y	All mutations	Y	2.9949717159019484	>1
103	G	T	All mutations	T	2.0	>1
104	P	Q	All mutations	Q	1.0364550597108737	1
104	P	K	All mutations	K	2.0364550597108737	>1
104	P	G	All mutations	G	2.0	>1
104	P	F	All mutations	F	2.9635449402891263	>1
104	P	N	All mutations	N	2.9635449402891263	>1
104	P	A	All mutations	A	1.0	1
104	P	W	All mutations	W	2.790069138906348	>1
104	P	C	All mutations	C	2.9635449402891263	>1
104	P	M	All mutations	M	2.790069138906348	>1
104	P	E	All mutations	E	2.0364550597108737	>1
104	P	D	All mutations	D	2.9635449402891263	>1
104	P	T	All mutations	T	1.0	1
104	P	H	All mutations	H	1.9635449402891263	>1
104	P	V	All mutations	V	2.0	>1
104	P	I	All mutations	I	2.209930861093652	>1
104	P	Y	All mutations	Y	2.9635449402891263	>1
104	P	L	All mutations	L	1.0	1
104	P	R	All mutations	R	1.0	1
104	P	P	All mutations	P	0.0	0
104	P	S	All mutations	S	1.0	1
105	T	Y	All mutations	Y	2.988686360779384	>1
105	T	K	All mutations	K	1.0131992457573853	1
105	T	S	All mutations	S	1.0295411690760528	1
105	T	E	All mutations	E	1.9993714644877436	>1
105	T	N	All mutations	N	1.9956002514142048	>1
105	T	I	All mutations	I	1.217473287240729	>1
105	T	C	All mutations	C	2.9905719673161535	>1
105	T	T	All mutations	T	0.03708359522313011	1
105	T	W	All mutations	W	2.761785040854808	>1
105	T	P	All mutations	P	1.0301697045883091	1
105	T	G	All mutations	G	1.9924575738529227	>1
105	T	V	All mutations	V	1.966059082338152	>1
105	T	H	All mutations	H	2.988686360779384	>1
105	T	D	All mutations	D	2.981772470144563	>1
105	T	F	All mutations	F	2.964173475801383	>1
105	T	R	All mutations	R	1.0150848522941547	1
105	T	A	All mutations	A	1.0232558139534884	1
105	T	L	All mutations	L	1.972972972972973	>1
105	T	Q	All mutations	Q	2.0062853551225643	>1
105	T	M	All mutations	M	1.7423004399748585	>1
106	T	W	All mutations	W	2.9849151477058453	>1
106	T	T	All mutations	T	0.14142049025769957	1
106	T	C	All mutations	C	2.9270898805782526	>1
106	T	M	All mutations	M	2.1156505342551855	>1
106	T	F	All mutations	F	2.922061596480201	>1
106	T	G	All mutations	G	1.8642363293526085	>1
106	T	R	All mutations	R	1.207416719044626	>1
106	T	E	All mutations	E	1.9365179132620993	>1
106	T	N	All mutations	N	2.0622250157133877	>1
106	T	V	All mutations	V	1.859208045254557	>1
106	T	S	All mutations	S	1.005656819610308	1
106	T	P	All mutations	P	1.005656819610308	1
106	T	K	All mutations	K	1.2080452545568825	>1
106	T	D	All mutations	D	2.7906976744186047	>1
106	T	L	All mutations	L	1.9949717159019484	>1
106	T	H	All mutations	H	2.9264613450659964	>1
106	T	A	All mutations	A	0.8698931489629164	1
106	T	Q	All mutations	Q	2.072281583909491	>1
106	T	I	All mutations	I	1.1458202388434946	>1
106	T	Y	All mutations	Y	2.9264613450659964	>1
107	S	M	All mutations	M	2.0	>1
107	S	R	All mutations	R	1.0729101194217474	1
107	S	C	All mutations	C	1.0741671904462602	1
107	S	N	All mutations	N	0.9270898805782527	1
107	S	H	All mutations	H	1.9270898805782526	>1
107	S	D	All mutations	D	1.9270898805782526	>1
107	S	E	All mutations	E	2.92583280955374	>1
107	S	T	All mutations	T	1.0	1
107	S	Y	All mutations	Y	1.9270898805782526	>1
107	S	I	All mutations	I	1.0	1
107	S	P	All mutations	P	2.0	>1
107	S	V	All mutations	V	2.0	>1
107	S	Q	All mutations	Q	2.92583280955374	>1
107	S	G	All mutations	G	1.0735386549340038	1
107	S	A	All mutations	A	2.0	>1
107	S	S	All mutations	S	0.07416719044626022	1
107	S	K	All mutations	K	1.9258328095537398	>1
107	S	F	All mutations	F	2.0006285355122566	>1
107	S	L	All mutations	L	2.0	>1
107	S	W	All mutations	W	2.0735386549340036	>1
108	T	N	All mutations	N	1.9792583280955374	>1
108	T	E	All mutations	E	2.0207416719044624	>1
108	T	D	All mutations	D	2.9692017598994345	>1
108	T	F	All mutations	F	2.971087366436204	>1
108	T	V	All mutations	V	1.9918290383406663	>1
108	T	S	All mutations	S	1.0031426775612822	1
108	T	R	All mutations	R	1.0301697045883091	1
108	T	H	All mutations	H	2.974230043997486	>1
108	T	P	All mutations	P	1.0031426775612822	1
108	T	K	All mutations	K	1.0307982401005658	1
108	T	Q	All mutations	Q	2.025769956002514	>1
108	T	M	All mutations	M	1.9648020113136393	>1
108	T	C	All mutations	C	2.974230043997486	>1
108	T	L	All mutations	L	1.9968573224387178	>1
108	T	G	All mutations	G	1.9949717159019484	>1
108	T	T	All mutations	T	0.008170961659333752	1
108	T	Y	All mutations	Y	2.974230043997486	>1
108	T	I	All mutations	I	1.0389692017598995	1
108	T	W	All mutations	W	2.9629164047768697	>1
108	T	A	All mutations	A	0.9981143934632307	1
109	V	H	All mutations	H	2.0150848522941547	>1
109	V	G	All mutations	G	1.043997485857951	1
109	V	D	All mutations	D	1.0597108736643621	1
109	V	S	All mutations	S	1.9566310496543056	>1
109	V	N	All mutations	N	1.9748585795097422	>1
109	V	T	All mutations	T	1.956002514142049	>1
109	V	M	All mutations	M	1.9585166561910747	>1
109	V	P	All mutations	P	1.9962287869264614	>1
109	V	Q	All mutations	Q	2.9836580766813325	>1
109	V	A	All mutations	A	1.0408548082966687	1
109	V	K	All mutations	K	2.94343180389692	>1
109	V	I	All mutations	I	0.9660590823381521	1
109	V	Y	All mutations	Y	2.0131992457573853	>1
109	V	C	All mutations	C	2.0131992457573853	>1
109	V	V	All mutations	V	0.04714016341923319	1
109	V	W	All mutations	W	2.9937146448774357	>1
109	V	R	All mutations	R	1.9993714644877436	>1
109	V	L	All mutations	L	1.0025141420490258	1
109	V	E	All mutations	E	2.02828409805154	>1
109	V	F	All mutations	F	1.0163419233186675	1
110	H	Q	All mutations	Q	1.0018856065367694	1
110	H	M	All mutations	M	2.9993714644877434	>1
110	H	K	All mutations	K	2.0006285355122566	>1
110	H	N	All mutations	N	1.0006285355122564	1
110	H	P	All mutations	P	1.0006285355122564	1
110	H	H	All mutations	H	0.0018856065367693275	1
110	H	Y	All mutations	Y	1.0012570710245128	1
110	H	C	All mutations	C	1.9987429289754872	>1
110	H	L	All mutations	L	1.0006285355122564	1
110	H	E	All mutations	E	2.001257071024513	>1
110	H	D	All mutations	D	1.0012570710245128	1
110	H	R	All mutations	R	0.9993714644877436	1
110	H	F	All mutations	F	2.0	>1
110	H	G	All mutations	G	1.9987429289754872	>1
110	H	A	All mutations	A	2.0	>1
110	H	I	All mutations	I	1.9993714644877436	>1
110	H	T	All mutations	T	1.9993714644877436	>1
110	H	V	All mutations	V	2.0	>1
110	H	S	All mutations	S	1.9981143934632306	>1
110	H	W	All mutations	W	2.998742928975487	>1
111	Y	A	All mutations	A	2.0	>1
111	Y	K	All mutations	K	2.0	>1
111	Y	W	All mutations	W	2.0	>1
111	Y	M	All mutations	M	3.0	>1
111	Y	P	All mutations	P	2.0	>1
111	Y	Y	All mutations	Y	0.0	0
111	Y	C	All mutations	C	1.0	1
111	Y	T	All mutations	T	2.0	>1
111	Y	G	All mutations	G	2.0	>1
111	Y	L	All mutations	L	2.0	>1
111	Y	Q	All mutations	Q	2.0	>1
111	Y	E	All mutations	E	2.0	>1
111	Y	S	All mutations	S	1.0	1
111	Y	V	All mutations	V	2.0	>1
111	Y	H	All mutations	H	1.0	1
111	Y	D	All mutations	D	1.0	1
111	Y	R	All mutations	R	2.0	>1
111	Y	N	All mutations	N	1.0	1
111	Y	F	All mutations	F	1.0	1
111	Y	I	All mutations	I	2.0	>1
112	P	S	All mutations	S	0.9993714644877436	1
112	P	M	All mutations	M	2.950345694531741	>1
112	P	N	All mutations	N	2.8340666247642994	>1
112	P	D	All mutations	D	2.8346951602765555	>1
112	P	F	All mutations	F	2.8340666247642994	>1
112	P	C	All mutations	C	2.8340666247642994	>1
112	P	I	All mutations	I	2.048397234443746	>1
112	P	A	All mutations	A	1.0	1
112	P	P	All mutations	P	0.001257071024512885	1
112	P	G	All mutations	G	2.0	>1
112	P	T	All mutations	T	0.9993714644877436	1
112	P	W	All mutations	W	2.950345694531741	>1
112	P	Q	All mutations	Q	1.1665619107479572	>1
112	P	Y	All mutations	Y	2.8340666247642994	>1
112	P	V	All mutations	V	2.0	>1
112	P	K	All mutations	K	2.164676304211188	>1
112	P	E	All mutations	E	2.1653048397234445	>1
112	P	H	All mutations	H	1.8359522313010685	>1
112	P	R	All mutations	R	1.0006285355122564	1
112	P	L	All mutations	L	1.0006285355122564	1
113	K	D	All mutations	D	2.0018856065367694	>1
113	K	C	All mutations	C	2.9981143934632306	>1
113	K	E	All mutations	E	1.0018856065367694	1
113	K	G	All mutations	G	1.9981143934632306	>1
113	K	H	All mutations	H	1.987429289754871	>1
113	K	I	All mutations	I	1.8535512256442488	>1
113	K	W	All mutations	W	2.15901948460088	>1
113	K	T	All mutations	T	1.014456316781898	1
113	K	V	All mutations	V	2.0	>1
113	K	Y	All mutations	Y	2.0018856065367694	>1
113	K	K	All mutations	K	0.016341923318667503	1
113	K	F	All mutations	F	3.0	>1
113	K	R	All mutations	R	0.9981143934632307	1
113	K	N	All mutations	N	1.0163419233186675	1
113	K	A	All mutations	A	2.0	>1
113	K	Q	All mutations	Q	0.9874292897548711	1
113	K	S	All mutations	S	1.9981143934632306	>1
113	K	P	All mutations	P	1.985543683218102	>1
113	K	M	All mutations	M	1.1753614079195474	>1
113	K	L	All mutations	L	1.985543683218102	>1
114	V	E	All mutations	E	1.4695160276555626	>1
114	V	M	All mutations	M	1.913262099308611	>1
114	V	I	All mutations	I	1.085480829666876	1
114	V	Q	All mutations	Q	2.468887492143306	>1
114	V	L	All mutations	L	1.0	1
114	V	K	All mutations	K	2.4682589566310495	>1
114	V	H	All mutations	H	2.531112507856694	>1
114	V	G	All mutations	G	1.0006285355122564	1
114	V	F	All mutations	F	1.5311125078566938	>1
114	V	D	All mutations	D	1.5317410433689505	>1
114	V	V	All mutations	V	0.0006285355122564425	1
114	V	Y	All mutations	Y	2.531112507856694	>1
114	V	W	All mutations	W	2.9138906348208673	>1
114	V	P	All mutations	P	2.0	>1
114	V	A	All mutations	A	1.0006285355122564	1
114	V	R	All mutations	R	2.0	>1
114	V	C	All mutations	C	2.531112507856694	>1
114	V	T	All mutations	T	1.9993714644877436	>1
114	V	S	All mutations	S	1.9993714644877436	>1
114	V	N	All mutations	N	2.5304839723444377	>1
115	Y	F	All mutations	F	1.0006285355122564	1
115	Y	R	All mutations	R	1.9993714644877436	>1
115	Y	H	All mutations	H	0.9993714644877436	1
115	Y	N	All mutations	N	1.0	1
115	Y	C	All mutations	C	1.0006285355122564	1
115	Y	I	All mutations	I	2.0	>1
115	Y	E	All mutations	E	2.0	>1
115	Y	D	All mutations	D	1.0	1
115	Y	S	All mutations	S	1.0006285355122564	1
115	Y	W	All mutations	W	2.0006285355122566	>1
115	Y	K	All mutations	K	2.0	>1
115	Y	Y	All mutations	Y	0.0006285355122564425	1
115	Y	P	All mutations	P	1.9993714644877436	>1
115	Y	V	All mutations	V	2.0	>1
115	Y	Q	All mutations	Q	1.9993714644877436	>1
115	Y	A	All mutations	A	2.0	>1
115	Y	T	All mutations	T	2.0	>1
115	Y	L	All mutations	L	1.9993714644877436	>1
115	Y	M	All mutations	M	3.0	>1
115	Y	G	All mutations	G	2.0	>1
116	K	F	All mutations	F	3.0	>1
116	K	G	All mutations	G	1.985543683218102	>1
116	K	H	All mutations	H	2.014456316781898	>1
116	K	T	All mutations	T	1.0	1
116	K	A	All mutations	A	2.0	>1
116	K	P	All mutations	P	2.0	>1
116	K	E	All mutations	E	1.014456316781898	1
116	K	C	All mutations	C	2.985543683218102	>1
116	K	N	All mutations	N	1.014456316781898	1
116	K	M	All mutations	M	1.935889377749843	>1
116	K	W	All mutations	W	2.921433060967945	>1
116	K	I	All mutations	I	1.064110622250157	1
116	K	S	All mutations	S	1.985543683218102	>1
116	K	L	All mutations	L	2.0	>1
116	K	K	All mutations	K	0.014456316781898177	1
116	K	D	All mutations	D	2.014456316781898	>1
116	K	V	All mutations	V	2.0	>1
116	K	Y	All mutations	Y	2.014456316781898	>1
116	K	Q	All mutations	Q	1.014456316781898	1
116	K	R	All mutations	R	0.9855436832181018	1
117	T	N	All mutations	N	1.2218730358265242	>1
117	T	L	All mutations	L	1.9924575738529227	>1
117	T	M	All mutations	M	1.9905719673161533	>1
117	T	V	All mutations	V	1.9987429289754872	>1
117	T	T	All mutations	T	0.008170961659333752	1
117	T	S	All mutations	S	1.0	1
117	T	P	All mutations	P	0.9937146448774355	1
117	T	H	All mutations	H	2.207416719044626	>1
117	T	G	All mutations	G	1.9993714644877436	>1
117	T	F	All mutations	F	2.2137020741671902	>1
117	T	A	All mutations	A	1.0	1
117	T	C	All mutations	C	2.214330609679447	>1
117	T	Y	All mutations	Y	2.214330609679447	>1
117	T	E	All mutations	E	2.7850408548082966	>1
117	T	K	All mutations	K	1.7932118164676305	>1
117	T	Q	All mutations	Q	2.778755499685732	>1
117	T	W	All mutations	W	2.9836580766813325	>1
117	T	D	All mutations	D	2.2137020741671902	>1
117	T	R	All mutations	R	1.7793840351979886	>1
117	T	I	All mutations	I	1.0232558139534884	1
118	Y	I	All mutations	I	2.0	>1
118	Y	D	All mutations	D	1.0	1
118	Y	E	All mutations	E	2.0	>1
118	Y	A	All mutations	A	2.0	>1
118	Y	Y	All mutations	Y	0.0	0
118	Y	M	All mutations	M	3.0	>1
118	Y	R	All mutations	R	2.0	>1
118	Y	T	All mutations	T	2.0	>1
118	Y	G	All mutations	G	2.0	>1
118	Y	W	All mutations	W	2.0	>1
118	Y	C	All mutations	C	1.0	1
118	Y	L	All mutations	L	2.0	>1
118	Y	N	All mutations	N	1.0	1
118	Y	Q	All mutations	Q	2.0	>1
118	Y	K	All mutations	K	2.0	>1
118	Y	S	All mutations	S	1.0	1
118	Y	V	All mutations	V	2.0	>1
118	Y	H	All mutations	H	1.0	1
118	Y	F	All mutations	F	1.0	1
118	Y	P	All mutations	P	2.0	>1
119	F	S	All mutations	S	1.0	1
119	F	D	All mutations	D	2.0	>1
119	F	C	All mutations	C	1.0	1
119	F	Y	All mutations	Y	1.0	1
119	F	V	All mutations	V	1.0	1
119	F	W	All mutations	W	2.0	>1
119	F	N	All mutations	N	2.0	>1
119	F	M	All mutations	M	2.0	>1
119	F	A	All mutations	A	2.0	>1
119	F	T	All mutations	T	2.0	>1
119	F	G	All mutations	G	2.0	>1
119	F	L	All mutations	L	1.0	1
119	F	Q	All mutations	Q	3.0	>1
119	F	E	All mutations	E	3.0	>1
119	F	I	All mutations	I	1.0	1
119	F	K	All mutations	K	3.0	>1
119	F	F	All mutations	F	0.0	0
119	F	H	All mutations	H	2.0	>1
119	F	P	All mutations	P	2.0	>1
119	F	R	All mutations	R	2.0	>1
120	E	L	All mutations	L	2.0	>1
120	E	F	All mutations	F	2.9981143934632306	>1
120	E	Y	All mutations	Y	2.006913890634821	>1
120	E	W	All mutations	W	2.7027027027027026	>1
120	E	S	All mutations	S	1.9993714644877436	>1
120	E	C	All mutations	C	2.989943431803897	>1
120	E	A	All mutations	A	1.0006285355122564	1
120	E	G	All mutations	G	0.9930861093651792	1
120	E	Q	All mutations	Q	1.0106851037083595	1
120	E	E	All mutations	E	0.011942174732872407	1
120	E	I	All mutations	I	2.287869264613451	>1
120	E	H	All mutations	H	2.006913890634821	>1
120	E	M	All mutations	M	2.7096165933375236	>1
120	E	R	All mutations	R	1.9905719673161533	>1
120	E	P	All mutations	P	1.9993714644877436	>1
120	E	N	All mutations	N	2.005656819610308	>1
120	E	T	All mutations	T	1.9981143934632306	>1
120	E	K	All mutations	K	1.0094280326838467	1
120	E	D	All mutations	D	1.0081709616593337	1
120	E	V	All mutations	V	1.0012570710245128	1
121	K	L	All mutations	L	2.0	>1
121	K	C	All mutations	C	2.9974858579509744	>1
121	K	D	All mutations	D	2.0025141420490256	>1
121	K	F	All mutations	F	3.0	>1
121	K	I	All mutations	I	1.4946574481458201	>1
121	K	A	All mutations	A	2.0	>1
121	K	T	All mutations	T	1.0	1
121	K	Y	All mutations	Y	2.0025141420490256	>1
121	K	M	All mutations	M	1.5053425518541799	>1
121	K	R	All mutations	R	0.9974858579509742	1
121	K	Q	All mutations	Q	1.0025141420490258	1
121	K	V	All mutations	V	2.0	>1
121	K	P	All mutations	P	2.0	>1
121	K	K	All mutations	K	0.00251414204902577	1
121	K	W	All mutations	W	2.502828409805154	>1
121	K	H	All mutations	H	2.0025141420490256	>1
121	K	S	All mutations	S	1.9974858579509742	>1
121	K	G	All mutations	G	1.9974858579509742	>1
121	K	N	All mutations	N	1.0025141420490258	1
121	K	E	All mutations	E	1.0025141420490258	1
122	V	M	All mutations	M	2.0094280326838465	>1
122	V	P	All mutations	P	1.9849151477058453	>1
122	V	Y	All mutations	Y	2.0263984915147706	>1
122	V	N	All mutations	N	2.0207416719044624	>1
122	V	C	All mutations	C	2.0263984915147706	>1
122	V	D	All mutations	D	1.0320553111250785	1
122	V	A	All mutations	A	0.9905719673161534	1
122	V	L	All mutations	L	1.0150848522941547	1
122	V	V	All mutations	V	0.020741671904462602	1
122	V	R	All mutations	R	2.0	>1
122	V	K	All mutations	K	2.9679446888749212	>1
122	V	G	All mutations	G	1.005656819610308	1
122	V	E	All mutations	E	1.9792583280955374	>1
122	V	H	All mutations	H	2.0263984915147706	>1
122	V	Q	All mutations	Q	2.9736015084852294	>1
122	V	F	All mutations	F	1.0414833438089253	1
122	V	S	All mutations	S	1.9792583280955374	>1
122	V	W	All mutations	W	3.0	>1
122	V	T	All mutations	T	1.9792583280955374	>1
122	V	I	All mutations	I	1.0094280326838467	1
123	E	I	All mutations	I	2.0835952231301067	>1
123	E	Q	All mutations	Q	1.0043997485857952	1
123	E	A	All mutations	A	1.0031426775612822	1
123	E	V	All mutations	V	1.0031426775612822	1
123	E	N	All mutations	N	1.9974858579509742	>1
123	E	W	All mutations	W	2.910747957259585	>1
123	E	Y	All mutations	Y	2.0006285355122566	>1
123	E	R	All mutations	R	1.994343180389692	>1
123	E	M	All mutations	M	2.9101194217473285	>1
123	E	P	All mutations	P	2.0	>1
123	E	S	All mutations	S	2.0	>1
123	E	K	All mutations	K	1.0012570710245128	1
123	E	C	All mutations	C	2.995600251414205	>1
123	E	G	All mutations	G	1.0006285355122564	1
123	E	D	All mutations	D	1.0037712130735386	1
123	E	F	All mutations	F	2.9981143934632306	>1
123	E	L	All mutations	L	2.0	>1
123	E	T	All mutations	T	1.9968573224387178	>1
123	E	H	All mutations	H	2.0006285355122566	>1
123	E	E	All mutations	E	0.00754242614707731	1
124	R	M	All mutations	M	1.230043997485858	>1
124	R	Q	All mutations	Q	2.0	>1
124	R	K	All mutations	K	1.0	1
124	R	W	All mutations	W	1.230043997485858	>1
124	R	P	All mutations	P	2.0	>1
124	R	G	All mutations	G	1.0	1
124	R	V	All mutations	V	2.0	>1
124	R	T	All mutations	T	1.0	1
124	R	E	All mutations	E	2.0	>1
124	R	D	All mutations	D	3.0	>1
124	R	H	All mutations	H	3.0	>1
124	R	A	All mutations	A	2.0	>1
124	R	N	All mutations	N	2.0	>1
124	R	F	All mutations	F	3.0	>1
124	R	I	All mutations	I	1.769956002514142	>1
124	R	C	All mutations	C	2.0	>1
124	R	L	All mutations	L	2.0	>1
124	R	S	All mutations	S	1.0	1
124	R	R	All mutations	R	0.0	0
124	R	Y	All mutations	Y	3.0	>1
125	L	K	All mutations	K	1.9962287869264614	>1
125	L	E	All mutations	E	2.0	>1
125	L	G	All mutations	G	2.0	>1
125	L	V	All mutations	V	1.0	1
125	L	Q	All mutations	Q	1.8661219358893777	>1
125	L	C	All mutations	C	2.137649277184161	>1
125	L	P	All mutations	P	1.8661219358893777	>1
125	L	D	All mutations	D	3.0	>1
125	L	L	All mutations	L	0.003771213073538655	1
125	L	R	All mutations	R	1.8623507228158391	>1
125	L	W	All mutations	W	1.6040226272784412	>1
125	L	N	All mutations	N	2.996228786926461	>1
125	L	H	All mutations	H	2.8661219358893777	>1
125	L	Y	All mutations	Y	2.137649277184161	>1
125	L	T	All mutations	T	1.9962287869264614	>1
125	L	I	All mutations	I	1.529855436832181	>1
125	L	S	All mutations	S	1.1376492771841609	>1
125	L	M	All mutations	M	1.4626021370207416	>1
125	L	A	All mutations	A	2.0	>1
125	L	F	All mutations	F	1.1376492771841609	>1
126	K	H	All mutations	H	2.006913890634821	>1
126	K	T	All mutations	T	1.0	1
126	K	L	All mutations	L	2.0	>1
126	K	G	All mutations	G	1.993086109365179	>1
126	K	S	All mutations	S	1.993086109365179	>1
126	K	P	All mutations	P	2.0	>1
126	K	Q	All mutations	Q	1.006913890634821	1
126	K	N	All mutations	N	1.006913890634821	1
126	K	M	All mutations	M	1.8007542426147076	>1
126	K	I	All mutations	I	1.1992457573852924	>1
126	K	Y	All mutations	Y	2.006913890634821	>1
126	K	R	All mutations	R	0.9930861093651792	1
126	K	K	All mutations	K	0.0069138906348208675	1
126	K	D	All mutations	D	2.006913890634821	>1
126	K	E	All mutations	E	1.006913890634821	1
126	K	C	All mutations	C	2.993086109365179	>1
126	K	V	All mutations	V	2.0	>1
126	K	F	All mutations	F	3.0	>1
126	K	W	All mutations	W	2.793840351979887	>1
126	K	A	All mutations	A	2.0	>1
127	H	P	All mutations	P	1.005656819610308	1
127	H	I	All mutations	I	1.9962287869264614	>1
127	H	F	All mutations	F	1.9974858579509742	>1
127	H	W	All mutations	W	2.988686360779384	>1
127	H	D	All mutations	D	1.0100565681961031	1
127	H	A	All mutations	A	2.0	>1
127	H	Y	All mutations	Y	1.0075424261470773	1
127	H	M	All mutations	M	2.996228786926461	>1
127	H	R	All mutations	R	0.9968573224387178	1
127	H	H	All mutations	H	0.01571338780641106	1
127	H	K	All mutations	K	2.005656819610308	>1
127	H	S	All mutations	S	1.985543683218102	>1
127	H	G	All mutations	G	1.9912005028284099	>1
127	H	V	All mutations	V	1.9993714644877436	>1
127	H	C	All mutations	C	1.9893148962916405	>1
127	H	Q	All mutations	Q	1.014456316781898	1
127	H	N	All mutations	N	1.006913890634821	1
127	H	E	All mutations	E	2.0087994971715903	>1
127	H	L	All mutations	L	1.0050282840980516	1
127	H	T	All mutations	T	1.9968573224387178	>1
128	G	S	All mutations	S	1.9912005028284099	>1
128	G	Y	All mutations	Y	2.9912005028284097	>1
128	G	L	All mutations	L	2.0	>1
128	G	E	All mutations	E	1.0087994971715901	1
128	G	F	All mutations	F	2.9912005028284097	>1
128	G	H	All mutations	H	2.9912005028284097	>1
128	G	R	All mutations	R	1.0	1
128	G	D	All mutations	D	1.9912005028284099	>1
128	G	P	All mutations	P	2.0	>1
128	G	T	All mutations	T	2.0	>1
128	G	Q	All mutations	Q	2.0087994971715903	>1
128	G	M	All mutations	M	2.47705845380264	>1
128	G	I	All mutations	I	2.52294154619736	>1
128	G	K	All mutations	K	2.0087994971715903	>1
128	G	G	All mutations	G	0.0	0
128	G	C	All mutations	C	1.9912005028284099	>1
128	G	N	All mutations	N	2.9912005028284097	>1
128	G	A	All mutations	A	1.0	1
128	G	V	All mutations	V	1.0	1
128	G	W	All mutations	W	1.47705845380264	>1
129	T	T	All mutations	T	0.008799497171590195	1
129	T	Q	All mutations	Q	2.9164047768698933	>1
129	T	D	All mutations	D	2.075424261470773	>1
129	T	F	All mutations	F	2.075424261470773	>1
129	T	Y	All mutations	Y	2.0760527969830296	>1
129	T	L	All mutations	L	1.9956002514142048	>1
129	T	C	All mutations	C	2.0798240100565684	>1
129	T	S	All mutations	S	1.0006285355122564	1
129	T	M	All mutations	M	1.9962287869264614	>1
129	T	H	All mutations	H	2.0760527969830296	>1
129	T	W	All mutations	W	3.0	>1
129	T	K	All mutations	K	1.9170333123821497	>1
129	T	N	All mutations	N	1.076681332495286	1
129	T	G	All mutations	G	1.9993714644877436	>1
129	T	E	All mutations	E	2.9157762413576367	>1
129	T	P	All mutations	P	1.0081709616593337	1
129	T	V	All mutations	V	1.9949717159019484	>1
129	T	I	All mutations	I	0.9962287869264613	1
129	T	A	All mutations	A	1.0075424261470773	1
129	T	R	All mutations	R	1.9201759899434319	>1
130	F	S	All mutations	S	1.0	1
130	F	T	All mutations	T	2.0	>1
130	F	G	All mutations	G	2.0	>1
130	F	R	All mutations	R	2.0	>1
130	F	H	All mutations	H	2.0	>1
130	F	Y	All mutations	Y	1.0	1
130	F	L	All mutations	L	1.0	1
130	F	A	All mutations	A	2.0	>1
130	F	Q	All mutations	Q	3.0	>1
130	F	M	All mutations	M	2.0	>1
130	F	K	All mutations	K	3.0	>1
130	F	C	All mutations	C	1.0	1
130	F	V	All mutations	V	1.0	1
130	F	W	All mutations	W	2.0	>1
130	F	P	All mutations	P	2.0	>1
130	F	D	All mutations	D	2.0	>1
130	F	I	All mutations	I	1.0	1
130	F	N	All mutations	N	2.0	>1
130	F	F	All mutations	F	0.0	0
130	F	E	All mutations	E	3.0	>1
131	G	Q	All mutations	Q	2.9937146448774357	>1
131	G	M	All mutations	M	2.9937146448774357	>1
131	G	P	All mutations	P	2.0	>1
131	G	T	All mutations	T	2.0	>1
131	G	I	All mutations	I	2.0062853551225643	>1
131	G	V	All mutations	V	1.0	1
131	G	N	All mutations	N	2.0062853551225643	>1
131	G	Y	All mutations	Y	2.0062853551225643	>1
131	G	S	All mutations	S	1.0062853551225643	1
131	G	F	All mutations	F	2.0062853551225643	>1
131	G	E	All mutations	E	1.9937146448774357	>1
131	G	K	All mutations	K	2.9937146448774357	>1
131	G	L	All mutations	L	2.0	>1
131	G	D	All mutations	D	1.0062853551225643	1
131	G	W	All mutations	W	1.9937146448774357	>1
131	G	H	All mutations	H	2.0062853551225643	>1
131	G	C	All mutations	C	1.0062853551225643	1
131	G	G	All mutations	G	0.0	0
131	G	A	All mutations	A	1.0	1
131	G	R	All mutations	R	1.0	1
132	P	E	All mutations	E	2.981772470144563	>1
132	P	W	All mutations	W	2.9993714644877434	>1
132	P	A	All mutations	A	1.0	1
132	P	H	All mutations	H	1.0182275298554369	1
132	P	P	All mutations	P	0.0	0
132	P	V	All mutations	V	2.0	>1
132	P	N	All mutations	N	2.018227529855437	>1
132	P	R	All mutations	R	1.0	1
132	P	C	All mutations	C	2.018227529855437	>1
132	P	D	All mutations	D	2.018227529855437	>1
132	P	L	All mutations	L	1.0	1
132	P	K	All mutations	K	2.981772470144563	>1
132	P	F	All mutations	F	2.018227529855437	>1
132	P	I	All mutations	I	2.0006285355122566	>1
132	P	S	All mutations	S	1.0	1
132	P	Y	All mutations	Y	2.018227529855437	>1
132	P	G	All mutations	G	2.0	>1
132	P	Q	All mutations	Q	1.9817724701445631	>1
132	P	M	All mutations	M	2.9993714644877434	>1
132	P	T	All mutations	T	1.0	1
133	V	K	All mutations	K	2.639220615964802	>1
133	V	G	All mutations	G	1.0006285355122564	1
133	V	M	All mutations	M	1.868007542426147	>1
133	V	C	All mutations	C	2.3601508485229417	>1
133	V	P	All mutations	P	2.0	>1
133	V	H	All mutations	H	2.3601508485229417	>1
133	V	E	All mutations	E	1.640477686989315	>1
133	V	T	All mutations	T	1.9993714644877436	>1
133	V	A	All mutations	A	1.0006285355122564	1
133	V	W	All mutations	W	2.8686360779384037	>1
133	V	N	All mutations	N	2.359522313010685	>1
133	V	V	All mutations	V	0.0006285355122564425	1
133	V	D	All mutations	D	1.360779384035198	>1
133	V	R	All mutations	R	1.9993714644877436	>1
133	V	F	All mutations	F	1.3601508485229414	>1
133	V	Y	All mutations	Y	2.3601508485229417	>1
133	V	Q	All mutations	Q	2.6398491514770583	>1
133	V	S	All mutations	S	2.0	>1
133	V	L	All mutations	L	1.0	1
133	V	I	All mutations	I	1.1307353865493401	>1
134	H	D	All mutations	D	1.0	1
134	H	L	All mutations	L	1.0	1
134	H	A	All mutations	A	2.0	>1
134	H	Y	All mutations	Y	1.0	1
134	H	M	All mutations	M	3.0	>1
134	H	R	All mutations	R	1.0	1
134	H	E	All mutations	E	2.0	>1
134	H	H	All mutations	H	0.0	0
134	H	S	All mutations	S	2.0	>1
134	H	K	All mutations	K	2.0	>1
134	H	G	All mutations	G	2.0	>1
134	H	T	All mutations	T	2.0	>1
134	H	P	All mutations	P	1.0	1
134	H	N	All mutations	N	1.0	1
134	H	C	All mutations	C	2.0	>1
134	H	I	All mutations	I	2.0	>1
134	H	Q	All mutations	Q	1.0	1
134	H	F	All mutations	F	2.0	>1
134	H	W	All mutations	W	3.0	>1
134	H	V	All mutations	V	2.0	>1
135	F	N	All mutations	N	2.0	>1
135	F	A	All mutations	A	2.0	>1
135	F	Q	All mutations	Q	3.0	>1
135	F	T	All mutations	T	2.0	>1
135	F	R	All mutations	R	2.0	>1
135	F	Y	All mutations	Y	1.0	1
135	F	H	All mutations	H	2.0	>1
135	F	S	All mutations	S	1.0	1
135	F	F	All mutations	F	0.0	0
135	F	L	All mutations	L	1.0	1
135	F	D	All mutations	D	2.0	>1
135	F	I	All mutations	I	1.0	1
135	F	E	All mutations	E	3.0	>1
135	F	P	All mutations	P	2.0	>1
135	F	V	All mutations	V	1.0	1
135	F	G	All mutations	G	2.0	>1
135	F	M	All mutations	M	2.0	>1
135	F	W	All mutations	W	2.0	>1
135	F	K	All mutations	K	3.0	>1
135	F	C	All mutations	C	1.0	1
136	R	W	All mutations	W	1.873664362036455	>1
136	R	Q	All mutations	Q	1.4996857322438717	>1
136	R	T	All mutations	T	1.5034569453174105	>1
136	R	F	All mutations	F	2.9949717159019484	>1
136	R	M	All mutations	M	2.3752357008170963	>1
136	R	G	All mutations	G	1.0018856065367694	1
136	R	C	All mutations	C	1.9968573224387178	>1
136	R	D	All mutations	D	2.993086109365179	>1
136	R	V	All mutations	V	2.0	>1
136	R	L	All mutations	L	1.4965430546825895	>1
136	R	S	All mutations	S	1.498428661219359	>1
136	R	E	All mutations	E	2.003142677561282	>1
136	R	N	All mutations	N	2.4965430546825895	>1
136	R	R	All mutations	R	0.0018856065367693275	1
136	R	I	All mutations	I	1.6316781898177246	>1
136	R	K	All mutations	K	1.5065996228786926	>1
136	R	Y	All mutations	Y	2.993086109365179	>1
136	R	P	All mutations	P	1.4965430546825895	>1
136	R	H	All mutations	H	2.4896291640477686	>1
136	R	A	All mutations	A	2.0	>1
137	N	I	All mutations	I	1.0	1
137	N	A	All mutations	A	2.0	>1
137	N	R	All mutations	R	1.9968573224387178	>1
137	N	N	All mutations	N	0.0031426775612822125	1
137	N	D	All mutations	D	1.0031426775612822	1
137	N	L	All mutations	L	2.0	>1
137	N	C	All mutations	C	1.9968573224387178	>1
137	N	K	All mutations	K	1.0031426775612822	1
137	N	G	All mutations	G	1.9968573224387178	>1
137	N	S	All mutations	S	0.9968573224387178	1
137	N	Y	All mutations	Y	1.0031426775612822	1
137	N	E	All mutations	E	2.003142677561282	>1
137	N	F	All mutations	F	2.0	>1
137	N	V	All mutations	V	2.0	>1
137	N	T	All mutations	T	1.0	1
137	N	H	All mutations	H	1.0031426775612822	1
137	N	P	All mutations	P	2.0	>1
137	N	W	All mutations	W	2.996857322438718	>1
137	N	Q	All mutations	Q	2.003142677561282	>1
137	N	M	All mutations	M	2.0	>1
138	Q	H	All mutations	H	1.0	1
138	Q	F	All mutations	F	2.9993714644877434	>1
138	Q	W	All mutations	W	2.7932118164676303	>1
138	Q	E	All mutations	E	1.0012570710245128	1
138	Q	S	All mutations	S	2.0	>1
138	Q	C	All mutations	C	2.998742928975487	>1
138	Q	Q	All mutations	Q	0.001257071024512885	1
138	Q	G	All mutations	G	1.9993714644877436	>1
138	Q	V	All mutations	V	2.0	>1
138	Q	D	All mutations	D	2.0	>1
138	Q	P	All mutations	P	1.0	1
138	Q	K	All mutations	K	1.0012570710245128	1
138	Q	T	All mutations	T	2.0	>1
138	Q	L	All mutations	L	1.0	1
138	Q	Y	All mutations	Y	2.0	>1
138	Q	A	All mutations	A	2.0	>1
138	Q	N	All mutations	N	2.0	>1
138	Q	M	All mutations	M	2.793840351979887	>1
138	Q	I	All mutations	I	2.206159648020113	>1
138	Q	R	All mutations	R	0.9993714644877436	1
139	V	P	All mutations	P	1.9974858579509742	>1
139	V	M	All mutations	M	1.836580766813325	>1
139	V	E	All mutations	E	2.1439346323067254	>1
139	V	C	All mutations	C	2.011313639220616	>1
139	V	S	All mutations	S	1.8447517284726587	>1
139	V	K	All mutations	K	2.8334380892520428	>1
139	V	N	All mutations	N	1.8560653676932746	>1
139	V	H	All mutations	H	2.011313639220616	>1
139	V	F	All mutations	F	1.0138277812696417	1
139	V	A	All mutations	A	1.1527341294783156	>1
139	V	W	All mutations	W	2.9893148962916403	>1
139	V	Q	All mutations	Q	2.988686360779384	>1
139	V	D	All mutations	D	1.1665619107479572	>1
139	V	V	All mutations	V	0.15776241357636706	1
139	V	R	All mutations	R	2.0	>1
139	V	T	All mutations	T	1.842237586423633	>1
139	V	G	All mutations	G	1.1552482715273413	>1
139	V	Y	All mutations	Y	2.011313639220616	>1
139	V	L	All mutations	L	1.0025141420490258	1
139	V	I	All mutations	I	0.857950974230044	1
140	K	D	All mutations	D	2.0006285355122566	>1
140	K	I	All mutations	I	1.4406033940917662	>1
140	K	C	All mutations	C	2.9993714644877434	>1
140	K	N	All mutations	N	1.0006285355122564	1
140	K	S	All mutations	S	1.9993714644877436	>1
140	K	M	All mutations	M	1.5593966059082338	>1
140	K	W	All mutations	W	2.558768070395977	>1
140	K	K	All mutations	K	0.0006285355122564425	1
140	K	R	All mutations	R	0.9993714644877436	1
140	K	Q	All mutations	Q	1.0006285355122564	1
140	K	Y	All mutations	Y	2.0006285355122566	>1
140	K	L	All mutations	L	2.0	>1
140	K	H	All mutations	H	2.0006285355122566	>1
140	K	E	All mutations	E	1.0006285355122564	1
140	K	V	All mutations	V	2.0	>1
140	K	T	All mutations	T	1.0	1
140	K	A	All mutations	A	2.0	>1
140	K	F	All mutations	F	3.0	>1
140	K	G	All mutations	G	1.9993714644877436	>1
140	K	P	All mutations	P	2.0	>1
141	I	H	All mutations	H	2.9993714644877434	>1
141	I	L	All mutations	L	1.0	1
141	I	N	All mutations	N	1.9993714644877436	>1
141	I	S	All mutations	S	1.9993714644877436	>1
141	I	R	All mutations	R	1.0006285355122564	1
141	I	G	All mutations	G	2.0	>1
141	I	D	All mutations	D	2.9993714644877434	>1
141	I	V	All mutations	V	1.0	1
141	I	F	All mutations	F	1.9993714644877436	>1
141	I	W	All mutations	W	3.0	>1
141	I	Y	All mutations	Y	2.9993714644877434	>1
141	I	Q	All mutations	Q	2.0006285355122566	>1
141	I	I	All mutations	I	0.0	0
141	I	M	All mutations	M	1.0	1
141	I	K	All mutations	K	1.0006285355122564	1
141	I	A	All mutations	A	2.0	>1
141	I	P	All mutations	P	2.0	>1
141	I	T	All mutations	T	1.0	1
141	I	E	All mutations	E	2.0006285355122566	>1
141	I	C	All mutations	C	2.9993714644877434	>1
142	R	L	All mutations	L	1.45757385292269	>1
142	R	A	All mutations	A	2.0	>1
142	R	P	All mutations	P	1.45757385292269	>1
142	R	C	All mutations	C	1.4795725958516657	>1
142	R	Y	All mutations	Y	2.4795725958516655	>1
142	R	E	All mutations	E	2.519798868636078	>1
142	R	G	All mutations	G	1.0	1
142	R	I	All mutations	I	1.6090509113764928	>1
142	R	F	All mutations	F	2.4795725958516655	>1
142	R	H	All mutations	H	1.937774984286612	>1
142	R	T	All mutations	T	1.5430546825895664	>1
142	R	V	All mutations	V	2.0	>1
142	R	Q	All mutations	Q	1.977372721558768	>1
142	R	M	All mutations	M	2.47705845380264	>1
142	R	S	All mutations	S	1.0232558139534884	1
142	R	R	All mutations	R	0.0006285355122564425	1
142	R	N	All mutations	N	2.0232558139534884	>1
142	R	D	All mutations	D	2.480201131363922	>1
142	R	K	All mutations	K	2.0628535512256443	>1
142	R	W	All mutations	W	1.9333752357008172	>1
143	R	L	All mutations	L	1.0138277812696417	1
143	R	Y	All mutations	Y	2.4670018856065368	>1
143	R	K	All mutations	K	2.5191703331238213	>1
143	R	G	All mutations	G	1.0	1
143	R	I	All mutations	I	2.423632935260842	>1
143	R	N	All mutations	N	2.453174104336895	>1
143	R	W	All mutations	W	1.562539283469516	>1
143	R	D	All mutations	D	2.4670018856065368	>1
143	R	R	All mutations	R	0.0	0
143	R	S	All mutations	S	1.453174104336895	>1
143	R	T	All mutations	T	1.9861722187303583	>1
143	R	V	All mutations	V	2.0	>1
143	R	A	All mutations	A	2.0	>1
143	R	E	All mutations	E	2.5329981143934632	>1
143	R	C	All mutations	C	1.4670018856065368	>1
143	R	M	All mutations	M	2.548711502199874	>1
143	R	P	All mutations	P	1.0138277812696417	1
143	R	Q	All mutations	Q	1.546825895663105	>1
143	R	H	All mutations	H	1.4808296668761785	>1
143	R	F	All mutations	F	2.4670018856065368	>1
144	R	D	All mutations	D	3.0	>1
144	R	S	All mutations	S	1.1709616593337524	>1
144	R	C	All mutations	C	2.0	>1
144	R	Y	All mutations	Y	3.0	>1
144	R	W	All mutations	W	1.2532998114393463	>1
144	R	I	All mutations	I	1.917661847894406	>1
144	R	A	All mutations	A	2.0	>1
144	R	V	All mutations	V	2.0	>1
144	R	T	All mutations	T	1.1709616593337524	>1
144	R	E	All mutations	E	2.0	>1
144	R	M	All mutations	M	1.4242614707730987	>1
144	R	Q	All mutations	Q	1.8290383406662476	>1
144	R	H	All mutations	H	2.829038340666248	>1
144	R	N	All mutations	N	2.170961659333752	>1
144	R	K	All mutations	K	1.1709616593337524	>1
144	R	F	All mutations	F	3.0	>1
144	R	G	All mutations	G	1.0	1
144	R	L	All mutations	L	1.8290383406662476	>1
144	R	P	All mutations	P	1.8290383406662476	>1
144	R	R	All mutations	R	0.0	0
145	V	R	All mutations	R	2.0	>1
145	V	W	All mutations	W	2.978629792583281	>1
145	V	V	All mutations	V	0.0	0
145	V	D	All mutations	D	1.0377121307353865	1
145	V	H	All mutations	H	2.0377121307353865	>1
145	V	T	All mutations	T	2.0	>1
145	V	Q	All mutations	Q	2.9622878692646135	>1
145	V	S	All mutations	S	2.0	>1
145	V	I	All mutations	I	1.021370207416719	1
145	V	G	All mutations	G	1.0	1
145	V	Y	All mutations	Y	2.0377121307353865	>1
145	V	L	All mutations	L	1.0	1
145	V	A	All mutations	A	1.0	1
145	V	C	All mutations	C	2.0377121307353865	>1
145	V	F	All mutations	F	1.0377121307353865	1
145	V	E	All mutations	E	1.9622878692646135	>1
145	V	K	All mutations	K	2.9622878692646135	>1
145	V	N	All mutations	N	2.0377121307353865	>1
145	V	M	All mutations	M	1.978629792583281	>1
145	V	P	All mutations	P	2.0	>1
146	D	Q	All mutations	Q	1.9981143934632306	>1
146	D	A	All mutations	A	1.0006285355122564	1
146	D	I	All mutations	I	2.001257071024513	>1
146	D	F	All mutations	F	2.0018856065367694	>1
146	D	P	All mutations	P	2.0	>1
146	D	C	All mutations	C	2.0018856065367694	>1
146	D	R	All mutations	R	2.0	>1
146	D	E	All mutations	E	0.9987429289754871	1
146	D	D	All mutations	D	0.00251414204902577	1
146	D	Y	All mutations	Y	1.0018856065367694	1
146	D	V	All mutations	V	1.0006285355122564	1
146	D	W	All mutations	W	2.9981143934632306	>1
146	D	G	All mutations	G	1.0006285355122564	1
146	D	S	All mutations	S	1.9993714644877436	>1
146	D	K	All mutations	K	1.9974858579509742	>1
146	D	M	All mutations	M	2.9974858579509744	>1
146	D	T	All mutations	T	1.9993714644877436	>1
146	D	L	All mutations	L	2.0	>1
146	D	H	All mutations	H	1.0018856065367694	1
146	D	N	All mutations	N	1.0012570710245128	1
147	I	V	All mutations	V	1.0942803268384664	1
147	I	F	All mutations	F	2.120678818353237	>1
147	I	A	All mutations	A	1.846637335009428	>1
147	I	T	All mutations	T	0.9063482086737901	1
147	I	M	All mutations	M	1.142049025769956	>1
147	I	R	All mutations	R	1.032683846637335	1
147	I	G	All mutations	G	1.9704588309239472	>1
147	I	P	All mutations	P	1.8761785040854808	>1
147	I	Q	All mutations	Q	2.0025141420490256	>1
147	I	K	All mutations	K	1.032683846637335	1
147	I	L	All mutations	L	1.1231929604022628	>1
147	I	H	All mutations	H	2.9974858579509744	>1
147	I	W	All mutations	W	2.9874292897548713	>1
147	I	Y	All mutations	Y	2.996857322438718	>1
147	I	E	All mutations	E	1.972972972972973	>1
147	I	I	All mutations	I	0.16593337523570081	1
147	I	S	All mutations	S	1.873664362036455	>1
147	I	N	All mutations	N	2.0276555625392834	>1
147	I	C	All mutations	C	2.996857322438718	>1
147	I	D	All mutations	D	2.9679446888749212	>1
148	N	D	All mutations	D	0.9993714644877436	1
148	N	N	All mutations	N	0.0006285355122564425	1
148	N	G	All mutations	G	1.9993714644877436	>1
148	N	C	All mutations	C	2.0	>1
148	N	H	All mutations	H	1.0	1
148	N	S	All mutations	S	1.0006285355122564	1
148	N	F	All mutations	F	2.0	>1
148	N	M	All mutations	M	2.0006285355122566	>1
148	N	T	All mutations	T	1.0006285355122564	1
148	N	P	All mutations	P	2.0	>1
148	N	A	All mutations	A	1.9993714644877436	>1
148	N	I	All mutations	I	1.0006285355122564	1
148	N	Q	All mutations	Q	2.0	>1
148	N	L	All mutations	L	2.0	>1
148	N	E	All mutations	E	1.9993714644877436	>1
148	N	K	All mutations	K	1.0006285355122564	1
148	N	W	All mutations	W	3.0	>1
148	N	Y	All mutations	Y	1.0	1
148	N	V	All mutations	V	1.9993714644877436	>1
148	N	R	All mutations	R	2.0	>1
149	P	Q	All mutations	Q	1.2363293526084225	>1
149	P	L	All mutations	L	1.0	1
149	P	G	All mutations	G	2.0	>1
149	P	M	All mutations	M	2.606536769327467	>1
149	P	C	All mutations	C	2.7630421118793214	>1
149	P	K	All mutations	K	2.2363293526084225	>1
149	P	W	All mutations	W	2.606536769327467	>1
149	P	T	All mutations	T	1.0006285355122564	1
149	P	I	All mutations	I	2.393463230672533	>1
149	P	Y	All mutations	Y	2.7624135763670647	>1
149	P	V	All mutations	V	2.0	>1
149	P	N	All mutations	N	2.7624135763670647	>1
149	P	D	All mutations	D	2.7624135763670647	>1
149	P	H	All mutations	H	1.7624135763670647	>1
149	P	R	All mutations	R	1.0	1
149	P	S	All mutations	S	1.0006285355122564	1
149	P	E	All mutations	E	2.2363293526084225	>1
149	P	A	All mutations	A	1.0006285355122564	1
149	P	F	All mutations	F	2.7630421118793214	>1
149	P	P	All mutations	P	0.0006285355122564425	1
150	G	L	All mutations	L	2.0	>1
150	G	Y	All mutations	Y	2.0087994971715903	>1
150	G	W	All mutations	W	1.9993714644877436	>1
150	G	C	All mutations	C	1.0087994971715901	1
150	G	V	All mutations	V	1.0	1
150	G	Q	All mutations	Q	2.9912005028284097	>1
150	G	A	All mutations	A	1.0	1
150	G	G	All mutations	G	0.0	0
150	G	T	All mutations	T	2.0	>1
150	G	S	All mutations	S	1.0087994971715901	1
150	G	D	All mutations	D	1.0087994971715901	1
150	G	M	All mutations	M	2.9993714644877434	>1
150	G	I	All mutations	I	2.0006285355122566	>1
150	G	R	All mutations	R	1.0	1
150	G	P	All mutations	P	2.0	>1
150	G	E	All mutations	E	1.9912005028284099	>1
150	G	F	All mutations	F	2.0087994971715903	>1
150	G	K	All mutations	K	2.9912005028284097	>1
150	G	N	All mutations	N	2.0087994971715903	>1
150	G	H	All mutations	H	2.0087994971715903	>1
151	H	Y	All mutations	Y	1.0	1
151	H	S	All mutations	S	2.0	>1
151	H	R	All mutations	R	1.0	1
151	H	N	All mutations	N	1.0	1
151	H	K	All mutations	K	2.0	>1
151	H	A	All mutations	A	2.0	>1
151	H	E	All mutations	E	2.0	>1
151	H	F	All mutations	F	2.0	>1
151	H	P	All mutations	P	1.0	1
151	H	G	All mutations	G	2.0	>1
151	H	I	All mutations	I	2.0	>1
151	H	M	All mutations	M	3.0	>1
151	H	H	All mutations	H	0.0	0
151	H	D	All mutations	D	1.0	1
151	H	T	All mutations	T	2.0	>1
151	H	V	All mutations	V	2.0	>1
151	H	W	All mutations	W	3.0	>1
151	H	C	All mutations	C	2.0	>1
151	H	Q	All mutations	Q	1.0	1
151	H	L	All mutations	L	1.0	1
152	A	G	All mutations	G	1.0559396605908233	1
152	A	E	All mutations	E	1.3865493400377122	>1
152	A	C	All mutations	C	2.6140791954745444	>1
152	A	N	All mutations	N	2.668761785040855	>1
152	A	Q	All mutations	Q	2.330609679446889	>1
152	A	H	All mutations	H	2.669390320553111	>1
152	A	S	All mutations	S	0.9453174104336896	1
152	A	T	All mutations	T	1.0	1
152	A	F	All mutations	F	2.6134506599622878	>1
152	A	P	All mutations	P	1.0006285355122564	1
152	A	M	All mutations	M	2.8900062853551227	>1
152	A	D	All mutations	D	1.7253299811439347	>1
152	A	V	All mutations	V	1.055311125078567	1
152	A	L	All mutations	L	1.9918290383406663	>1
152	A	A	All mutations	A	0.056568196103079824	1
152	A	W	All mutations	W	2.8359522313010683	>1
152	A	R	All mutations	R	1.9993714644877436	>1
152	A	Y	All mutations	Y	2.6140791954745444	>1
152	A	I	All mutations	I	2.1074795725958517	>1
152	A	K	All mutations	K	2.3299811439346323	>1
153	D	E	All mutations	E	1.0043997485857952	1
153	D	W	All mutations	W	2.9974858579509744	>1
153	D	D	All mutations	D	0.0043997485857950975	1
153	D	P	All mutations	P	2.0	>1
153	D	R	All mutations	R	1.9974858579509742	>1
153	D	N	All mutations	N	1.0006285355122564	1
153	D	Q	All mutations	Q	2.0025141420490256	>1
153	D	H	All mutations	H	1.0025141420490258	1
153	D	K	All mutations	K	2.0006285355122566	>1
153	D	T	All mutations	T	1.9981143934632306	>1
153	D	F	All mutations	F	2.0	>1
153	D	S	All mutations	S	1.9956002514142048	>1
153	D	M	All mutations	M	2.9981143934632306	>1
153	D	G	All mutations	G	0.9993714644877436	1
153	D	V	All mutations	V	1.0018856065367694	1
153	D	Y	All mutations	Y	1.0025141420490258	1
153	D	C	All mutations	C	1.9974858579509742	>1
153	D	A	All mutations	A	1.0018856065367694	1
153	D	L	All mutations	L	2.0	>1
153	D	I	All mutations	I	1.9981143934632306	>1
154	L	D	All mutations	D	2.003142677561282	>1
154	L	I	All mutations	I	0.9993714644877436	1
154	L	Q	All mutations	Q	1.9981143934632306	>1
154	L	V	All mutations	V	1.0	1
154	L	F	All mutations	F	1.0025141420490258	1
154	L	R	All mutations	R	1.0012570710245128	1
154	L	M	All mutations	M	1.9993714644877436	>1
154	L	P	All mutations	P	1.0012570710245128	1
154	L	A	All mutations	A	2.0	>1
154	L	T	All mutations	T	1.9993714644877436	>1
154	L	H	All mutations	H	1.0043997485857952	1
154	L	S	All mutations	S	1.9987429289754872	>1
154	L	L	All mutations	L	0.001257071024512885	1
154	L	N	All mutations	N	2.0025141420490256	>1
154	L	C	All mutations	C	2.0025141420490256	>1
154	L	G	All mutations	G	2.0	>1
154	L	K	All mutations	K	2.996228786926461	>1
154	L	E	All mutations	E	2.996857322438718	>1
154	L	W	All mutations	W	2.9993714644877434	>1
154	L	Y	All mutations	Y	2.0025141420490256	>1
155	S	C	All mutations	C	1.0131992457573853	1
155	S	R	All mutations	R	1.0119421747328725	1
155	S	Q	All mutations	Q	2.9893148962916403	>1
155	S	N	All mutations	N	0.9905719673161534	1
155	S	W	All mutations	W	2.0119421747328725	>1
155	S	V	All mutations	V	1.9993714644877436	>1
155	S	E	All mutations	E	2.9893148962916403	>1
155	S	F	All mutations	F	2.0	>1
155	S	I	All mutations	I	1.0	1
155	S	H	All mutations	H	1.9905719673161533	>1
155	S	Y	All mutations	Y	1.9905719673161533	>1
155	S	P	All mutations	P	1.9981143934632306	>1
155	S	G	All mutations	G	1.012570710245129	1
155	S	D	All mutations	D	1.9905719673161533	>1
155	S	A	All mutations	A	1.9981143934632306	>1
155	S	M	All mutations	M	1.9987429289754872	>1
155	S	S	All mutations	S	0.013199245757385292	1
155	S	K	All mutations	K	1.9893148962916405	>1
155	S	L	All mutations	L	1.9993714644877436	>1
155	S	T	All mutations	T	0.9981143934632307	1
156	A	Q	All mutations	Q	2.9082338152105596	>1
156	A	P	All mutations	P	1.0006285355122564	1
156	A	E	All mutations	E	1.9151477058453803	>1
156	A	G	All mutations	G	1.006913890634821	1
156	A	K	All mutations	K	2.9069767441860463	>1
156	A	L	All mutations	L	2.0	>1
156	A	Y	All mutations	Y	2.08485229415462	>1
156	A	F	All mutations	F	2.085480829666876	>1
156	A	N	All mutations	N	2.089252042740415	>1
156	A	S	All mutations	S	0.9949717159019484	1
156	A	V	All mutations	V	1.006913890634821	1
156	A	H	All mutations	H	2.0905091137649277	>1
156	A	A	All mutations	A	0.00754242614707731	1
156	A	D	All mutations	D	1.0974230043997486	1
156	A	T	All mutations	T	0.9993714644877436	1
156	A	I	All mutations	I	2.076681332495286	>1
156	A	W	All mutations	W	2.9164047768698933	>1
156	A	R	All mutations	R	2.0	>1
156	A	C	All mutations	C	2.085480829666876	>1
156	A	M	All mutations	M	2.9208045254556882	>1
157	K	T	All mutations	T	1.0012570710245128	1
157	K	G	All mutations	G	1.9968573224387178	>1
157	K	E	All mutations	E	1.0006285355122564	1
157	K	M	All mutations	M	1.886235072281584	>1
157	K	V	All mutations	V	1.9987429289754872	>1
157	K	D	All mutations	D	2.0006285355122566	>1
157	K	K	All mutations	K	0.0031426775612822125	1
157	K	Y	All mutations	Y	2.0018856065367694	>1
157	K	I	All mutations	I	1.1162790697674418	>1
157	K	L	All mutations	L	2.0	>1
157	K	P	All mutations	P	2.0	>1
157	K	S	All mutations	S	1.9981143934632306	>1
157	K	R	All mutations	R	0.9993714644877436	1
157	K	H	All mutations	H	2.0018856065367694	>1
157	K	F	All mutations	F	3.0	>1
157	K	C	All mutations	C	2.9981143934632306	>1
157	K	Q	All mutations	Q	1.0018856065367694	1
157	K	W	All mutations	W	2.8830923947203018	>1
157	K	A	All mutations	A	1.9987429289754872	>1
157	K	N	All mutations	N	1.0031426775612822	1
158	E	T	All mutations	T	2.0	>1
158	E	N	All mutations	N	2.0006285355122566	>1
158	E	F	All mutations	F	3.0	>1
158	E	K	All mutations	K	1.0006285355122564	1
158	E	Y	All mutations	Y	2.0006285355122566	>1
158	E	G	All mutations	G	0.9993714644877436	1
158	E	C	All mutations	C	2.9993714644877434	>1
158	E	S	All mutations	S	2.0	>1
158	E	L	All mutations	L	2.0	>1
158	E	W	All mutations	W	2.5285983658076683	>1
158	E	M	All mutations	M	2.5292269013199244	>1
158	E	D	All mutations	D	1.0006285355122564	1
158	E	I	All mutations	I	2.4707730986800756	>1
158	E	Q	All mutations	Q	1.0006285355122564	1
158	E	P	All mutations	P	2.0	>1
158	E	R	All mutations	R	1.9993714644877436	>1
158	E	H	All mutations	H	2.0006285355122566	>1
158	E	A	All mutations	A	1.0	1
158	E	V	All mutations	V	1.0	1
158	E	E	All mutations	E	0.0006285355122564425	1
159	A	V	All mutations	V	1.0006285355122564	1
159	A	Q	All mutations	Q	2.0125707102451287	>1
159	A	Y	All mutations	Y	2.9868007542426147	>1
159	A	I	All mutations	I	2.352608422375864	>1
159	A	D	All mutations	D	1.987429289754871	>1
159	A	W	All mutations	W	2.647391577624136	>1
159	A	F	All mutations	F	2.9868007542426147	>1
159	A	T	All mutations	T	1.0	1
159	A	N	All mutations	N	2.9868007542426147	>1
159	A	E	All mutations	E	1.0138277812696417	1
159	A	M	All mutations	M	2.647391577624136	>1
159	A	L	All mutations	L	1.9993714644877436	>1
159	A	P	All mutations	P	0.9993714644877436	1
159	A	H	All mutations	H	2.986172218730358	>1
159	A	C	All mutations	C	2.9868007542426147	>1
159	A	S	All mutations	S	1.0	1
159	A	K	All mutations	K	2.0131992457573853	>1
159	A	G	All mutations	G	1.0006285355122564	1
159	A	R	All mutations	R	1.9993714644877436	>1
159	A	A	All mutations	A	0.0006285355122564425	1
160	Q	C	All mutations	C	3.0	>1
160	Q	F	All mutations	F	3.0	>1
160	Q	I	All mutations	I	2.5065996228786926	>1
160	Q	N	All mutations	N	2.0	>1
160	Q	S	All mutations	S	2.0	>1
160	Q	H	All mutations	H	1.0	1
160	Q	R	All mutations	R	1.0	1
160	Q	A	All mutations	A	2.0	>1
160	Q	M	All mutations	M	2.4934003771213074	>1
160	Q	T	All mutations	T	2.0	>1
160	Q	K	All mutations	K	1.0	1
160	Q	L	All mutations	L	1.0	1
160	Q	P	All mutations	P	1.0	1
160	Q	W	All mutations	W	2.4934003771213074	>1
160	Q	V	All mutations	V	2.0	>1
160	Q	E	All mutations	E	1.0	1
160	Q	Y	All mutations	Y	2.0	>1
160	Q	G	All mutations	G	2.0	>1
160	Q	D	All mutations	D	2.0	>1
160	Q	Q	All mutations	Q	0.0	0
161	D	Q	All mutations	Q	1.9974858579509742	>1
161	D	I	All mutations	I	1.9993714644877436	>1
161	D	D	All mutations	D	0.0031426775612822125	1
161	D	R	All mutations	R	2.0	>1
161	D	W	All mutations	W	3.0	>1
161	D	P	All mutations	P	2.0	>1
161	D	H	All mutations	H	1.0025141420490258	1
161	D	M	All mutations	M	2.9993714644877434	>1
161	D	T	All mutations	T	1.9993714644877436	>1
161	D	A	All mutations	A	1.0006285355122564	1
161	D	G	All mutations	G	1.0006285355122564	1
161	D	C	All mutations	C	2.0025141420490256	>1
161	D	K	All mutations	K	1.9968573224387178	>1
161	D	F	All mutations	F	2.0025141420490256	>1
161	D	V	All mutations	V	1.0006285355122564	1
161	D	L	All mutations	L	2.0	>1
161	D	N	All mutations	N	1.0018856065367694	1
161	D	Y	All mutations	Y	1.0025141420490258	1
161	D	E	All mutations	E	0.9981143934632307	1
161	D	S	All mutations	S	1.9993714644877436	>1
162	V	S	All mutations	S	1.9993714644877436	>1
162	V	L	All mutations	L	1.0006285355122564	1
162	V	W	All mutations	W	2.9767441860465116	>1
162	V	P	All mutations	P	1.9993714644877436	>1
162	V	T	All mutations	T	1.9993714644877436	>1
162	V	I	All mutations	I	1.0238843494657448	1
162	V	E	All mutations	E	1.5348837209302326	>1
162	V	V	All mutations	V	0.0006285355122564425	1
162	V	D	All mutations	D	1.4651162790697674	>1
162	V	Y	All mutations	Y	2.4651162790697674	>1
162	V	H	All mutations	H	2.4651162790697674	>1
162	V	N	All mutations	N	2.4651162790697674	>1
162	V	C	All mutations	C	2.4651162790697674	>1
162	V	R	All mutations	R	2.0	>1
162	V	M	All mutations	M	1.977372721558768	>1
162	V	F	All mutations	F	1.465744814582024	>1
162	V	A	All mutations	A	0.9993714644877436	1
162	V	K	All mutations	K	2.5348837209302326	>1
162	V	G	All mutations	G	1.0	1
162	V	Q	All mutations	Q	2.5348837209302326	>1
163	I	P	All mutations	P	2.0	>1
163	I	W	All mutations	W	2.9993714644877434	>1
163	I	F	All mutations	F	1.1257071024512886	>1
163	I	G	All mutations	G	1.9987429289754872	>1
163	I	H	All mutations	H	2.1263356379635447	>1
163	I	D	All mutations	D	2.125078566939032	>1
163	I	C	All mutations	C	2.1257071024512886	>1
163	I	E	All mutations	E	2.872407291011942	>1
163	I	S	All mutations	S	1.1275927089880577	>1
163	I	N	All mutations	N	1.1282212445003144	>1
163	I	A	All mutations	A	1.9987429289754872	>1
163	I	Y	All mutations	Y	2.1257071024512886	>1
163	I	V	All mutations	V	0.9987429289754871	1
163	I	Q	All mutations	Q	2.8736643620364553	>1
163	I	T	All mutations	T	1.0018856065367694	1
163	I	K	All mutations	K	1.8755499685732244	>1
163	I	L	All mutations	L	1.0	1
163	I	I	All mutations	I	0.0018856065367693275	1
163	I	R	All mutations	R	1.873664362036455	>1
163	I	M	All mutations	M	1.0018856065367694	1
164	M	V	All mutations	V	1.0006285355122564	1
164	M	E	All mutations	E	2.0	>1
164	M	L	All mutations	L	1.0006285355122564	1
164	M	N	All mutations	N	2.0	>1
164	M	S	All mutations	S	1.9993714644877436	>1
164	M	K	All mutations	K	1.0	1
164	M	T	All mutations	T	1.0	1
164	M	D	All mutations	D	3.0	>1
164	M	A	All mutations	A	2.0	>1
164	M	I	All mutations	I	1.0006285355122564	1
164	M	F	All mutations	F	2.0006285355122566	>1
164	M	Q	All mutations	Q	2.0	>1
164	M	C	All mutations	C	2.9993714644877434	>1
164	M	G	All mutations	G	1.9993714644877436	>1
164	M	H	All mutations	H	3.0	>1
164	M	M	All mutations	M	0.0006285355122564425	1
164	M	W	All mutations	W	1.9993714644877436	>1
164	M	R	All mutations	R	0.9993714644877436	1
164	M	Y	All mutations	Y	3.0	>1
164	M	P	All mutations	P	2.0	>1
165	E	E	All mutations	E	0.0	0
165	E	L	All mutations	L	2.0	>1
165	E	N	All mutations	N	2.0	>1
165	E	Y	All mutations	Y	2.0	>1
165	E	Q	All mutations	Q	1.0	1
165	E	W	All mutations	W	2.5619107479572594	>1
165	E	H	All mutations	H	2.0	>1
165	E	I	All mutations	I	2.4380892520427406	>1
165	E	D	All mutations	D	1.0	1
165	E	R	All mutations	R	2.0	>1
165	E	P	All mutations	P	2.0	>1
165	E	A	All mutations	A	1.0	1
165	E	V	All mutations	V	1.0	1
165	E	M	All mutations	M	2.5619107479572594	>1
165	E	G	All mutations	G	1.0	1
165	E	K	All mutations	K	1.0	1
165	E	C	All mutations	C	3.0	>1
165	E	T	All mutations	T	2.0	>1
165	E	F	All mutations	F	3.0	>1
165	E	S	All mutations	S	2.0	>1
166	V	Y	All mutations	Y	2.024512884978001	>1
166	V	M	All mutations	M	1.9767441860465116	>1
166	V	V	All mutations	V	0.0056568196103079825	1
166	V	T	All mutations	T	1.994343180389692	>1
166	V	C	All mutations	C	2.024512884978001	>1
166	V	D	All mutations	D	1.0301697045883091	1
166	V	Q	All mutations	Q	2.975487115021999	>1
166	V	P	All mutations	P	2.0	>1
166	V	I	All mutations	I	1.0119421747328725	1
166	V	R	All mutations	R	2.0	>1
166	V	F	All mutations	F	1.0245128849780012	1
166	V	H	All mutations	H	2.024512884978001	>1
166	V	E	All mutations	E	1.9811439346323068	>1
166	V	G	All mutations	G	1.005656819610308	1
166	V	W	All mutations	W	2.9824010056568198	>1
166	V	K	All mutations	K	2.9698302954116906	>1
166	V	L	All mutations	L	1.0	1
166	V	A	All mutations	A	1.005656819610308	1
166	V	S	All mutations	S	1.994343180389692	>1
166	V	N	All mutations	N	2.0188560653676935	>1
167	V	E	All mutations	E	1.8145820238843495	>1
167	V	M	All mutations	M	1.9968573224387178	>1
167	V	K	All mutations	K	2.8145820238843493	>1
167	V	L	All mutations	L	1.0	1
167	V	H	All mutations	H	2.1854179761156507	>1
167	V	P	All mutations	P	2.0	>1
167	V	C	All mutations	C	2.1854179761156507	>1
167	V	W	All mutations	W	2.996857322438718	>1
167	V	A	All mutations	A	1.0	1
167	V	R	All mutations	R	2.0	>1
167	V	Q	All mutations	Q	2.8145820238843493	>1
167	V	D	All mutations	D	1.1854179761156505	>1
167	V	V	All mutations	V	0.0	0
167	V	T	All mutations	T	2.0	>1
167	V	Y	All mutations	Y	2.1854179761156507	>1
167	V	N	All mutations	N	2.1854179761156507	>1
167	V	I	All mutations	I	1.0031426775612822	1
167	V	G	All mutations	G	1.0	1
167	V	F	All mutations	F	1.1854179761156505	>1
167	V	S	All mutations	S	2.0	>1
168	F	C	All mutations	C	1.0	1
168	F	D	All mutations	D	1.9974858579509742	>1
168	F	Y	All mutations	Y	0.9974858579509742	1
168	F	T	All mutations	T	2.0	>1
168	F	R	All mutations	R	2.0	>1
168	F	A	All mutations	A	2.0	>1
168	F	W	All mutations	W	2.0	>1
168	F	P	All mutations	P	2.0	>1
168	F	H	All mutations	H	1.9974858579509742	>1
168	F	F	All mutations	F	0.00251414204902577	1
168	F	I	All mutations	I	1.0025141420490258	1
168	F	V	All mutations	V	1.0025141420490258	1
168	F	N	All mutations	N	1.9974858579509742	>1
168	F	L	All mutations	L	1.0025141420490258	1
168	F	Q	All mutations	Q	2.9974858579509744	>1
168	F	M	All mutations	M	2.0025141420490256	>1
168	F	S	All mutations	S	1.0	1
168	F	K	All mutations	K	2.9974858579509744	>1
168	F	G	All mutations	G	2.0	>1
168	F	E	All mutations	E	2.9974858579509744	>1
169	P	N	All mutations	N	2.9993714644877434	>1
169	P	A	All mutations	A	1.0	1
169	P	Y	All mutations	Y	3.0	>1
169	P	L	All mutations	L	1.0006285355122564	1
169	P	S	All mutations	S	1.0	1
169	P	I	All mutations	I	2.006913890634821	>1
169	P	F	All mutations	F	3.0	>1
169	P	C	All mutations	C	3.0	>1
169	P	H	All mutations	H	2.0006285355122566	>1
169	P	K	All mutations	K	1.9993714644877436	>1
169	P	R	All mutations	R	1.0	1
169	P	P	All mutations	P	0.0006285355122564425	1
169	P	T	All mutations	T	0.9993714644877436	1
169	P	M	All mutations	M	2.9918290383406663	>1
169	P	E	All mutations	E	2.0	>1
169	P	D	All mutations	D	3.0	>1
169	P	W	All mutations	W	2.992457573852923	>1
169	P	Q	All mutations	Q	1.0006285355122564	1
169	P	G	All mutations	G	2.0	>1
169	P	V	All mutations	V	2.0	>1
170	N	M	All mutations	M	2.0	>1
170	N	A	All mutations	A	2.0	>1
170	N	Y	All mutations	Y	1.0	1
170	N	P	All mutations	P	2.0	>1
170	N	T	All mutations	T	1.0	1
170	N	Q	All mutations	Q	2.0	>1
170	N	C	All mutations	C	2.0	>1
170	N	K	All mutations	K	1.0	1
170	N	N	All mutations	N	0.0	0
170	N	W	All mutations	W	3.0	>1
170	N	I	All mutations	I	1.0	1
170	N	F	All mutations	F	2.0	>1
170	N	H	All mutations	H	1.0	1
170	N	V	All mutations	V	2.0	>1
170	N	G	All mutations	G	2.0	>1
170	N	E	All mutations	E	2.0	>1
170	N	R	All mutations	R	2.0	>1
170	N	L	All mutations	L	2.0	>1
170	N	D	All mutations	D	1.0	1
170	N	S	All mutations	S	1.0	1
171	E	G	All mutations	G	1.0006285355122564	1
171	E	C	All mutations	C	3.0	>1
171	E	H	All mutations	H	2.0	>1
171	E	Q	All mutations	Q	1.0	1
171	E	R	All mutations	R	1.9993714644877436	>1
171	E	L	All mutations	L	2.0	>1
171	E	N	All mutations	N	1.9993714644877436	>1
171	E	Y	All mutations	Y	2.0	>1
171	E	F	All mutations	F	3.0	>1
171	E	T	All mutations	T	1.9993714644877436	>1
171	E	M	All mutations	M	2.912005028284098	>1
171	E	D	All mutations	D	1.0006285355122564	1
171	E	V	All mutations	V	1.0006285355122564	1
171	E	K	All mutations	K	0.9993714644877436	1
171	E	S	All mutations	S	2.0	>1
171	E	I	All mutations	I	2.086737900691389	>1
171	E	W	All mutations	W	2.9126335637963545	>1
171	E	A	All mutations	A	1.0006285355122564	1
171	E	P	All mutations	P	2.0	>1
171	E	E	All mutations	E	0.0006285355122564425	1
172	V	T	All mutations	T	1.9981143934632306	>1
172	V	E	All mutations	E	1.3130106851037084	>1
172	V	D	All mutations	D	1.6920175989943431	>1
172	V	Y	All mutations	Y	2.688874921433061	>1
172	V	F	All mutations	F	1.688874921433061	>1
172	V	V	All mutations	V	0.00251414204902577	1
172	V	G	All mutations	G	1.0025141420490258	1
172	V	N	All mutations	N	2.687617850408548	>1
172	V	M	All mutations	M	1.3576367064739159	>1
172	V	A	All mutations	A	1.0025141420490258	1
172	V	I	All mutations	I	1.6385920804525456	>1
172	V	S	All mutations	S	1.9981143934632306	>1
172	V	W	All mutations	W	2.358893777498429	>1
172	V	Q	All mutations	Q	2.3104965430546827	>1
172	V	L	All mutations	L	1.0	1
172	V	R	All mutations	R	1.9993714644877436	>1
172	V	H	All mutations	H	2.6895034569453173	>1
172	V	K	All mutations	K	2.3086109365179133	>1
172	V	P	All mutations	P	2.0	>1
172	V	C	All mutations	C	2.688874921433061	>1
173	G	W	All mutations	W	1.9283469516027656	>1
173	G	M	All mutations	M	2.9283469516027654	>1
173	G	T	All mutations	T	2.0	>1
173	G	R	All mutations	R	1.0	1
173	G	D	All mutations	D	1.97171590194846	>1
173	G	Y	All mutations	Y	2.97171590194846	>1
173	G	Q	All mutations	Q	2.02828409805154	>1
173	G	S	All mutations	S	1.97171590194846	>1
173	G	F	All mutations	F	2.97171590194846	>1
173	G	A	All mutations	A	1.0	1
173	G	P	All mutations	P	2.0	>1
173	G	G	All mutations	G	0.0	0
173	G	K	All mutations	K	2.02828409805154	>1
173	G	H	All mutations	H	2.97171590194846	>1
173	G	N	All mutations	N	2.97171590194846	>1
173	G	V	All mutations	V	1.0	1
173	G	I	All mutations	I	2.0716530483972346	>1
173	G	C	All mutations	C	1.97171590194846	>1
173	G	L	All mutations	L	2.0	>1
173	G	E	All mutations	E	1.02828409805154	1
174	A	I	All mutations	I	2.3570081709616595	>1
174	A	W	All mutations	W	2.6429918290383405	>1
174	A	K	All mutations	K	2.5405405405405403	>1
174	A	D	All mutations	D	1.4594594594594594	>1
174	A	V	All mutations	V	1.0	1
174	A	G	All mutations	G	1.0	1
174	A	M	All mutations	M	2.6429918290383405	>1
174	A	Y	All mutations	Y	2.4594594594594597	>1
174	A	F	All mutations	F	2.4594594594594597	>1
174	A	R	All mutations	R	2.0	>1
174	A	E	All mutations	E	1.5405405405405406	>1
174	A	N	All mutations	N	2.4594594594594597	>1
174	A	A	All mutations	A	0.0	0
174	A	L	All mutations	L	2.0	>1
174	A	Q	All mutations	Q	2.5405405405405403	>1
174	A	P	All mutations	P	1.0	1
174	A	H	All mutations	H	2.4594594594594597	>1
174	A	S	All mutations	S	1.0	1
174	A	C	All mutations	C	2.4594594594594597	>1
174	A	T	All mutations	T	1.0	1
175	R	G	All mutations	G	1.0194846008799496	1
175	R	R	All mutations	R	0.01948460087994972	1
175	R	T	All mutations	T	1.0131992457573853	1
175	R	L	All mutations	L	1.9868007542426147	>1
175	R	C	All mutations	C	2.0194846008799496	>1
175	R	S	All mutations	S	1.032683846637335	1
175	R	K	All mutations	K	0.9937146448774355	1
175	R	D	All mutations	D	2.9805153991200504	>1
175	R	I	All mutations	I	1.3909490886235072	>1
175	R	A	All mutations	A	2.0	>1
175	R	Y	All mutations	Y	2.9805153991200504	>1
175	R	M	All mutations	M	1.6354494028912634	>1
175	R	P	All mutations	P	1.9868007542426147	>1
175	R	Q	All mutations	Q	1.967316153362665	>1
175	R	F	All mutations	F	3.0	>1
175	R	W	All mutations	W	1.6417347580138277	>1
175	R	N	All mutations	N	1.9937146448774357	>1
175	R	V	All mutations	V	2.0	>1
175	R	H	All mutations	H	2.967316153362665	>1
175	R	E	All mutations	E	1.9805153991200504	>1
176	I	S	All mutations	S	1.9905719673161533	>1
176	I	A	All mutations	A	1.9993714644877436	>1
176	I	P	All mutations	P	2.0	>1
176	I	E	All mutations	E	2.0087994971715903	>1
176	I	M	All mutations	M	1.0006285355122564	1
176	I	K	All mutations	K	1.0100565681961031	1
176	I	G	All mutations	G	1.9993714644877436	>1
176	I	V	All mutations	V	0.9993714644877436	1
176	I	D	All mutations	D	2.989943431803897	>1
176	I	Y	All mutations	Y	2.9905719673161535	>1
176	I	I	All mutations	I	0.0006285355122564425	1
176	I	Q	All mutations	Q	2.0094280326838465	>1
176	I	C	All mutations	C	2.9905719673161535	>1
176	I	T	All mutations	T	1.0006285355122564	1
176	I	H	All mutations	H	2.9905719673161535	>1
176	I	F	All mutations	F	1.9905719673161533	>1
176	I	L	All mutations	L	1.0	1
176	I	R	All mutations	R	1.0100565681961031	1
176	I	W	All mutations	W	3.0	>1
176	I	N	All mutations	N	1.9912005028284099	>1
177	L	N	All mutations	N	2.974230043997486	>1
177	L	K	All mutations	K	2.025769956002514	>1
177	L	T	All mutations	T	2.0	>1
177	L	L	All mutations	L	0.0006285355122564425	1
177	L	S	All mutations	S	1.4808296668761785	>1
177	L	G	All mutations	G	1.9993714644877436	>1
177	L	D	All mutations	D	2.974230043997486	>1
177	L	Y	All mutations	Y	2.4550597108736643	>1
177	L	P	All mutations	P	1.5191703331238215	>1
177	L	A	All mutations	A	2.0	>1
177	L	I	All mutations	I	1.8416090509113765	>1
177	L	M	All mutations	M	1.1596480201131365	>1
177	L	E	All mutations	E	2.025769956002514	>1
177	L	V	All mutations	V	1.0006285355122564	1
177	L	C	All mutations	C	2.454431175361408	>1
177	L	H	All mutations	H	2.4934003771213074	>1
177	L	Q	All mutations	Q	1.5449402891263357	>1
177	L	F	All mutations	F	1.4556882463859209	>1
177	L	W	All mutations	W	1.639220615964802	>1
177	L	R	All mutations	R	1.5185417976115652	>1
178	T	A	All mutations	A	0.9352608422375864	1
178	T	R	All mutations	R	1.160276555625393	>1
178	T	V	All mutations	V	1.9352608422375863	>1
178	T	Y	All mutations	Y	2.839723444374607	>1
178	T	D	All mutations	D	2.77561282212445	>1
178	T	F	All mutations	F	2.839723444374607	>1
178	T	T	All mutations	T	0.06536769327467001	1
178	T	S	All mutations	S	0.9993714644877436	1
178	T	L	All mutations	L	1.9993714644877436	>1
178	T	W	All mutations	W	2.761156505342552	>1
178	T	I	All mutations	I	1.3035826524198617	>1
178	T	K	All mutations	K	1.2250157133878063	>1
178	T	M	All mutations	M	1.8271527341294782	>1
178	T	G	All mutations	G	1.9352608422375863	>1
178	T	C	All mutations	C	2.839723444374607	>1
178	T	P	All mutations	P	1.0	1
178	T	N	All mutations	N	1.9057196731615336	>1
178	T	E	All mutations	E	2.0949088623507226	>1
178	T	H	All mutations	H	2.8403519798868637	>1
178	T	Q	All mutations	Q	2.1596480201131363	>1
179	S	Q	All mutations	Q	2.011313639220616	>1
179	S	L	All mutations	L	1.011313639220616	1
179	S	P	All mutations	P	1.0	1
179	S	W	All mutations	W	1.5317410433689505	>1
179	S	F	All mutations	F	1.988686360779384	>1
179	S	N	All mutations	N	2.988686360779384	>1
179	S	V	All mutations	V	2.0	>1
179	S	I	All mutations	I	2.4682589566310495	>1
179	S	A	All mutations	A	1.0	1
179	S	R	All mutations	R	2.0	>1
179	S	H	All mutations	H	2.988686360779384	>1
179	S	E	All mutations	E	2.011313639220616	>1
179	S	C	All mutations	C	1.988686360779384	>1
179	S	M	All mutations	M	2.5317410433689505	>1
179	S	G	All mutations	G	2.0	>1
179	S	Y	All mutations	Y	1.988686360779384	>1
179	S	S	All mutations	S	0.0	0
179	S	K	All mutations	K	2.011313639220616	>1
179	S	D	All mutations	D	2.988686360779384	>1
179	S	T	All mutations	T	1.0	1
180	E	F	All mutations	F	3.0	>1
180	E	V	All mutations	V	1.0	1
180	E	N	All mutations	N	2.0	>1
180	E	Y	All mutations	Y	2.0	>1
180	E	E	All mutations	E	0.0	0
180	E	C	All mutations	C	3.0	>1
180	E	D	All mutations	D	1.0	1
180	E	Q	All mutations	Q	1.0	1
180	E	R	All mutations	R	2.0	>1
180	E	T	All mutations	T	2.0	>1
180	E	K	All mutations	K	1.0	1
180	E	S	All mutations	S	2.0	>1
180	E	W	All mutations	W	2.1169076052796982	>1
180	E	M	All mutations	M	2.1169076052796982	>1
180	E	H	All mutations	H	2.0	>1
180	E	I	All mutations	I	2.8830923947203018	>1
180	E	L	All mutations	L	2.0	>1
180	E	P	All mutations	P	2.0	>1
180	E	G	All mutations	G	1.0	1
180	E	A	All mutations	A	1.0	1
181	S	C	All mutations	C	1.9541169076052798	>1
181	S	L	All mutations	L	1.0471401634192332	1
181	S	W	All mutations	W	1.917661847894406	>1
181	S	F	All mutations	F	1.9541169076052798	>1
181	S	M	All mutations	M	2.9164047768698933	>1
181	S	E	All mutations	E	2.046511627906977	>1
181	S	P	All mutations	P	1.0	1
181	S	N	All mutations	N	2.952859836580767	>1
181	S	G	All mutations	G	2.0	>1
181	S	K	All mutations	K	2.04588309239472	>1
181	S	I	All mutations	I	2.082338152105594	>1
181	S	Q	All mutations	Q	2.046511627906977	>1
181	S	Y	All mutations	Y	1.9541169076052798	>1
181	S	V	All mutations	V	2.0	>1
181	S	T	All mutations	T	0.9993714644877436	1
181	S	R	All mutations	R	1.9993714644877436	>1
181	S	H	All mutations	H	2.953488372093023	>1
181	S	D	All mutations	D	2.953488372093023	>1
181	S	A	All mutations	A	1.0	1
181	S	S	All mutations	S	0.0006285355122564425	1
182	Q	A	All mutations	A	2.0	>1
182	Q	G	All mutations	G	2.0	>1
182	Q	T	All mutations	T	2.0	>1
182	Q	M	All mutations	M	2.790069138906348	>1
182	Q	F	All mutations	F	3.0	>1
182	Q	V	All mutations	V	2.0	>1
182	Q	Y	All mutations	Y	2.0	>1
182	Q	D	All mutations	D	2.0	>1
182	Q	W	All mutations	W	2.790069138906348	>1
182	Q	C	All mutations	C	3.0	>1
182	Q	L	All mutations	L	1.0	1
182	Q	S	All mutations	S	2.0	>1
182	Q	I	All mutations	I	2.209930861093652	>1
182	Q	K	All mutations	K	1.0	1
182	Q	Q	All mutations	Q	0.0	0
182	Q	E	All mutations	E	1.0	1
182	Q	N	All mutations	N	2.0	>1
182	Q	R	All mutations	R	1.0	1
182	Q	H	All mutations	H	1.0	1
182	Q	P	All mutations	P	1.0	1
183	L	D	All mutations	D	2.9993714644877434	>1
183	L	P	All mutations	P	1.698931489629164	>1
183	L	Y	All mutations	Y	2.387806411062225	>1
183	L	H	All mutations	H	2.6983029541169077	>1
183	L	R	All mutations	R	1.6115650534255186	>1
183	L	A	All mutations	A	2.0	>1
183	L	I	All mutations	I	1.6555625392834694	>1
183	L	L	All mutations	L	0.08736643620364551	1
183	L	K	All mutations	K	1.913262099308611	>1
183	L	N	All mutations	N	2.912005028284098	>1
183	L	W	All mutations	W	1.6455059710873665	>1
183	L	T	All mutations	T	1.9126335637963545	>1
183	L	S	All mutations	S	1.3884349465744814	>1
183	L	C	All mutations	C	2.387806411062225	>1
183	L	G	All mutations	G	2.0	>1
183	L	V	All mutations	V	1.0	1
183	L	Q	All mutations	Q	1.6995600251414205	>1
183	L	M	All mutations	M	1.1697045883092394	>1
183	L	F	All mutations	F	1.387806411062225	>1
183	L	E	All mutations	E	2.0006285355122566	>1
184	T	V	All mutations	V	1.9736015084852294	>1
184	T	R	All mutations	R	1.0295411690760528	1
184	T	M	All mutations	M	1.5191703331238215	>1
184	T	Y	All mutations	Y	2.981772470144563	>1
184	T	D	All mutations	D	2.9629164047768697	>1
184	T	S	All mutations	S	1.0087994971715901	1
184	T	A	All mutations	A	0.9899434318038969	1
184	T	E	All mutations	E	1.9968573224387178	>1
184	T	Q	All mutations	Q	2.015713387806411	>1
184	T	H	All mutations	H	2.981772470144563	>1
184	T	T	All mutations	T	0.02765556253928347	1
184	T	P	All mutations	P	1.0087994971715901	1
184	T	F	All mutations	F	2.975487115021999	>1
184	T	C	All mutations	C	2.983029541169076	>1
184	T	I	All mutations	I	1.5034569453174105	>1
184	T	L	All mutations	L	1.9924575738529227	>1
184	T	K	All mutations	K	1.0345694531741043	1
184	T	G	All mutations	G	1.9811439346323068	>1
184	T	N	All mutations	N	2.0006285355122566	>1
184	T	W	All mutations	W	2.5078566939032054	>1
185	I	E	All mutations	E	2.0062853551225643	>1
185	I	L	All mutations	L	1.0	1
185	I	D	All mutations	D	2.9836580766813325	>1
185	I	P	All mutations	P	2.0	>1
185	I	W	All mutations	W	3.0	>1
185	I	Y	All mutations	Y	2.988686360779384	>1
185	I	H	All mutations	H	2.988686360779384	>1
185	I	Q	All mutations	Q	2.011313639220616	>1
185	I	K	All mutations	K	1.0163419233186675	1
185	I	T	All mutations	T	1.0050282840980516	1
185	I	G	All mutations	G	1.9949717159019484	>1
185	I	R	All mutations	R	1.0163419233186675	1
185	I	I	All mutations	I	0.00502828409805154	1
185	I	F	All mutations	F	1.988686360779384	>1
185	I	C	All mutations	C	2.988686360779384	>1
185	I	N	All mutations	N	1.9937146448774357	>1
185	I	V	All mutations	V	0.9949717159019484	1
185	I	M	All mutations	M	1.0050282840980516	1
185	I	A	All mutations	A	1.9949717159019484	>1
185	I	S	All mutations	S	1.988686360779384	>1
186	T	V	All mutations	V	2.0	>1
186	T	H	All mutations	H	2.8969201759899432	>1
186	T	L	All mutations	L	2.0	>1
186	T	G	All mutations	G	2.0	>1
186	T	M	All mutations	M	1.8774355751099938	>1
186	T	T	All mutations	T	0.0	0
186	T	R	All mutations	R	1.1030798240100566	>1
186	T	A	All mutations	A	1.0	1
186	T	I	All mutations	I	1.1225644248900062	>1
186	T	C	All mutations	C	2.8969201759899432	>1
186	T	N	All mutations	N	1.8969201759899434	>1
186	T	F	All mutations	F	2.8969201759899432	>1
186	T	S	All mutations	S	1.0	1
186	T	Q	All mutations	Q	2.1030798240100568	>1
186	T	K	All mutations	K	1.1030798240100566	>1
186	T	Y	All mutations	Y	2.8969201759899432	>1
186	T	P	All mutations	P	1.0	1
186	T	E	All mutations	E	2.1030798240100568	>1
186	T	D	All mutations	D	2.8969201759899432	>1
186	T	W	All mutations	W	2.8774355751099936	>1
187	R	M	All mutations	M	1.3343808925204275	>1
187	R	K	All mutations	K	0.023884349465744813	1
187	R	R	All mutations	R	0.9761156505342552	1
187	R	S	All mutations	S	1.9761156505342552	>1
187	R	V	All mutations	V	2.0	>1
187	R	T	All mutations	T	1.0	1
187	R	A	All mutations	A	2.0	>1
187	R	G	All mutations	G	1.9761156505342552	>1
187	R	L	All mutations	L	2.0	>1
187	R	W	All mutations	W	2.3104965430546827	>1
187	R	C	All mutations	C	2.976115650534255	>1
187	R	F	All mutations	F	3.0	>1
187	R	Y	All mutations	Y	2.023884349465745	>1
187	R	E	All mutations	E	1.0238843494657448	1
187	R	I	All mutations	I	1.6656191074795725	>1
187	R	D	All mutations	D	2.023884349465745	>1
187	R	P	All mutations	P	2.0	>1
187	R	N	All mutations	N	1.0238843494657448	1
187	R	H	All mutations	H	2.023884349465745	>1
187	R	Q	All mutations	Q	1.0238843494657448	1
188	E	F	All mutations	F	3.0	>1
188	E	Q	All mutations	Q	1.0012570710245128	1
188	E	E	All mutations	E	0.00251414204902577	1
188	E	R	All mutations	R	1.9974858579509742	>1
188	E	A	All mutations	A	1.0012570710245128	1
188	E	N	All mutations	N	2.0	>1
188	E	H	All mutations	H	2.001257071024513	>1
188	E	M	All mutations	M	2.419233186675047	>1
188	E	L	All mutations	L	2.0	>1
188	E	Y	All mutations	Y	2.001257071024513	>1
188	E	C	All mutations	C	2.998742928975487	>1
188	E	K	All mutations	K	1.0	1
188	E	I	All mutations	I	2.5782526712759273	>1
188	E	W	All mutations	W	2.419233186675047	>1
188	E	V	All mutations	V	1.0012570710245128	1
188	E	D	All mutations	D	1.0025141420490258	1
188	E	S	All mutations	S	2.0	>1
188	E	P	All mutations	P	2.0	>1
188	E	G	All mutations	G	1.0	1
188	E	T	All mutations	T	1.9987429289754872	>1
189	K	C	All mutations	C	3.0	>1
189	K	M	All mutations	M	1.1489629164047768	>1
189	K	P	All mutations	P	2.0	>1
189	K	E	All mutations	E	1.0	1
189	K	H	All mutations	H	2.0	>1
189	K	Y	All mutations	Y	2.0	>1
189	K	D	All mutations	D	2.0	>1
189	K	A	All mutations	A	2.0	>1
189	K	R	All mutations	R	1.0	1
189	K	F	All mutations	F	3.0	>1
189	K	G	All mutations	G	2.0	>1
189	K	K	All mutations	K	0.0	0
189	K	L	All mutations	L	2.0	>1
189	K	N	All mutations	N	1.0	1
189	K	Q	All mutations	Q	1.0	1
189	K	I	All mutations	I	1.8510370835952232	>1
189	K	S	All mutations	S	2.0	>1
189	K	T	All mutations	T	1.0	1
189	K	V	All mutations	V	2.0	>1
189	K	W	All mutations	W	2.148962916404777	>1
190	K	A	All mutations	A	2.0	>1
190	K	W	All mutations	W	2.339409176618479	>1
190	K	V	All mutations	V	2.0	>1
190	K	F	All mutations	F	3.0	>1
190	K	L	All mutations	L	2.0	>1
190	K	C	All mutations	C	2.993086109365179	>1
190	K	I	All mutations	I	1.6536769327467002	>1
190	K	G	All mutations	G	1.993086109365179	>1
190	K	Y	All mutations	Y	2.006913890634821	>1
190	K	R	All mutations	R	0.9930861093651792	1
190	K	M	All mutations	M	1.3463230672532998	>1
190	K	N	All mutations	N	1.006913890634821	1
190	K	K	All mutations	K	0.0069138906348208675	1
190	K	D	All mutations	D	2.006913890634821	>1
190	K	E	All mutations	E	1.006913890634821	1
190	K	T	All mutations	T	1.0	1
190	K	Q	All mutations	Q	1.006913890634821	1
190	K	P	All mutations	P	2.0	>1
190	K	H	All mutations	H	2.006913890634821	>1
190	K	S	All mutations	S	1.993086109365179	>1
191	E	Q	All mutations	Q	1.0006285355122564	1
191	E	N	All mutations	N	1.9893148962916405	>1
191	E	A	All mutations	A	1.0100565681961031	1
191	E	H	All mutations	H	1.9993714644877436	>1
191	E	F	All mutations	F	2.9993714644877434	>1
191	E	G	All mutations	G	1.0100565681961031	1
191	E	Y	All mutations	Y	1.9993714644877436	>1
191	E	L	All mutations	L	2.0	>1
191	E	C	All mutations	C	2.9993714644877434	>1
191	E	I	All mutations	I	2.2306725329981143	>1
191	E	W	All mutations	W	2.7592708988057826	>1
191	E	D	All mutations	D	1.0094280326838467	1
191	E	P	All mutations	P	2.0	>1
191	E	S	All mutations	S	2.0	>1
191	E	K	All mutations	K	0.9905719673161534	1
191	E	M	All mutations	M	2.7492143306096795	>1
191	E	R	All mutations	R	1.9899434318038969	>1
191	E	V	All mutations	V	1.0100565681961031	1
191	E	E	All mutations	E	0.010685103708359522	1
191	E	T	All mutations	T	1.9899434318038969	>1
192	E	Y	All mutations	Y	2.0	>1
192	E	W	All mutations	W	2.700188560653677	>1
192	E	C	All mutations	C	3.0	>1
192	E	S	All mutations	S	2.0	>1
192	E	F	All mutations	F	3.0	>1
192	E	N	All mutations	N	2.0	>1
192	E	L	All mutations	L	2.0	>1
192	E	I	All mutations	I	2.299811439346323	>1
192	E	H	All mutations	H	2.0	>1
192	E	V	All mutations	V	1.0	1
192	E	D	All mutations	D	1.0	1
192	E	T	All mutations	T	2.0	>1
192	E	A	All mutations	A	1.0	1
192	E	Q	All mutations	Q	1.0	1
192	E	E	All mutations	E	0.0	0
192	E	M	All mutations	M	2.700188560653677	>1
192	E	G	All mutations	G	1.0	1
192	E	R	All mutations	R	2.0	>1
192	E	K	All mutations	K	1.0	1
192	E	P	All mutations	P	2.0	>1
193	L	K	All mutations	K	2.9880578252671275	>1
193	L	L	All mutations	L	0.0006285355122564425	1
193	L	E	All mutations	E	2.988686360779384	>1
193	L	I	All mutations	I	1.0043997485857952	1
193	L	Y	All mutations	Y	2.0050282840980516	>1
193	L	P	All mutations	P	1.006913890634821	1
193	L	D	All mutations	D	2.011313639220616	>1
193	L	M	All mutations	M	1.994343180389692	>1
193	L	T	All mutations	T	1.9993714644877436	>1
193	L	F	All mutations	F	1.0050282840980516	1
193	L	S	All mutations	S	1.993086109365179	>1
193	L	W	All mutations	W	2.988686360779384	>1
193	L	V	All mutations	V	1.0	1
193	L	C	All mutations	C	2.0050282840980516	>1
193	L	Q	All mutations	Q	1.9956002514142048	>1
193	L	N	All mutations	N	2.0106851037083597	>1
193	L	R	All mutations	R	1.006913890634821	1
193	L	A	All mutations	A	2.0	>1
193	L	H	All mutations	H	1.0182275298554369	1
193	L	G	All mutations	G	2.0	>1
194	Q	L	All mutations	L	1.0	1
194	Q	K	All mutations	K	1.011313639220616	1
194	Q	M	All mutations	M	2.13953488372093	>1
194	Q	S	All mutations	S	2.0	>1
194	Q	A	All mutations	A	2.0	>1
194	Q	T	All mutations	T	2.0	>1
194	Q	P	All mutations	P	1.0	1
194	Q	R	All mutations	R	0.9993714644877436	1
194	Q	D	All mutations	D	1.9899434318038969	>1
194	Q	W	All mutations	W	2.138906348208674	>1
194	Q	C	All mutations	C	2.988686360779384	>1
194	Q	F	All mutations	F	2.9893148962916403	>1
194	Q	Q	All mutations	Q	0.011313639220615965	1
194	Q	V	All mutations	V	2.0	>1
194	Q	I	All mutations	I	2.86046511627907	>1
194	Q	H	All mutations	H	0.9899434318038969	1
194	Q	N	All mutations	N	1.9899434318038969	>1
194	Q	E	All mutations	E	1.011313639220616	1
194	Q	Y	All mutations	Y	1.9899434318038969	>1
194	Q	G	All mutations	G	1.9993714644877436	>1
195	D	P	All mutations	P	2.0	>1
195	D	Y	All mutations	Y	1.0389692017598995	1
195	D	R	All mutations	R	1.9968573224387178	>1
195	D	V	All mutations	V	1.038340666247643	1
195	D	E	All mutations	E	1.005656819610308	1
195	D	M	All mutations	M	2.9610307982401007	>1
195	D	C	All mutations	C	2.032683846637335	>1
195	D	F	All mutations	F	2.035826524198617	>1
195	D	K	All mutations	K	1.928975487115022	>1
195	D	Q	All mutations	Q	1.967316153362665	>1
195	D	I	All mutations	I	1.9622878692646135	>1
195	D	N	All mutations	N	1.0006285355122564	1
195	D	L	All mutations	L	2.0	>1
195	D	G	All mutations	G	1.0351979886863607	1
195	D	W	All mutations	W	2.996228786926461	>1
195	D	D	All mutations	D	0.07730986800754243	1
195	D	H	All mutations	H	1.0389692017598995	1
195	D	T	All mutations	T	1.961659333752357	>1
195	D	A	All mutations	A	1.038340666247643	1
195	D	S	All mutations	S	1.961659333752357	>1
196	C	H	All mutations	H	2.0006285355122566	>1
196	C	D	All mutations	D	2.0006285355122566	>1
196	C	L	All mutations	L	1.9987429289754872	>1
196	C	P	All mutations	P	2.0	>1
196	C	Q	All mutations	Q	2.9993714644877434	>1
196	C	C	All mutations	C	0.001257071024512885	1
196	C	G	All mutations	G	1.0006285355122564	1
196	C	M	All mutations	M	2.998742928975487	>1
196	C	Y	All mutations	Y	1.0006285355122564	1
196	C	A	All mutations	A	2.0	>1
196	C	R	All mutations	R	1.0006285355122564	1
196	C	T	All mutations	T	2.0	>1
196	C	S	All mutations	S	1.0	1
196	C	K	All mutations	K	2.9993714644877434	>1
196	C	V	All mutations	V	1.9993714644877436	>1
196	C	E	All mutations	E	2.9993714644877434	>1
196	C	N	All mutations	N	2.0006285355122566	>1
196	C	I	All mutations	I	2.0	>1
196	C	F	All mutations	F	1.0	1
196	C	W	All mutations	W	1.0	1
197	K	Q	All mutations	Q	1.021370207416719	1
197	K	E	All mutations	E	1.0219987429289754	1
197	K	S	All mutations	S	1.9780012570710246	>1
197	K	G	All mutations	G	1.9805153991200504	>1
197	K	T	All mutations	T	1.0006285355122564	1
197	K	F	All mutations	F	2.9974858579509744	>1
197	K	R	All mutations	R	0.983029541169076	1
197	K	P	All mutations	P	1.9993714644877436	>1
197	K	M	All mutations	M	1.549968573224387	>1
197	K	N	All mutations	N	1.0175989943431805	1
197	K	Y	All mutations	Y	2.016970458830924	>1
197	K	C	All mutations	C	2.9780012570710244	>1
197	K	I	All mutations	I	1.4512884978001257	>1
197	K	L	All mutations	L	1.9993714644877436	>1
197	K	V	All mutations	V	2.0	>1
197	K	W	All mutations	W	2.529855436832181	>1
197	K	H	All mutations	H	2.0163419233186675	>1
197	K	A	All mutations	A	2.0	>1
197	K	D	All mutations	D	2.016970458830924	>1
197	K	K	All mutations	K	0.02262727844123193	1
198	I	H	All mutations	H	2.0553111250785667	>1
198	I	M	All mutations	M	1.0018856065367694	1
198	I	I	All mutations	I	0.0018856065367693275	1
198	I	C	All mutations	C	2.057196731615336	>1
198	I	P	All mutations	P	2.0	>1
198	I	G	All mutations	G	2.0	>1
198	I	L	All mutations	L	1.0018856065367694	1
198	I	Q	All mutations	Q	2.9409176618478945	>1
198	I	K	All mutations	K	1.9409176618478945	>1
198	I	A	All mutations	A	2.0	>1
198	I	N	All mutations	N	1.055311125078567	1
198	I	S	All mutations	S	1.0571967316153363	1
198	I	D	All mutations	D	2.0553111250785667	>1
198	I	F	All mutations	F	1.0590823381521055	1
198	I	W	All mutations	W	3.0	>1
198	I	T	All mutations	T	1.0	1
198	I	R	All mutations	R	1.9428032683846637	>1
198	I	E	All mutations	E	2.9409176618478945	>1
198	I	V	All mutations	V	1.0018856065367694	1
198	I	Y	All mutations	Y	2.0553111250785667	>1
199	A	Q	All mutations	Q	2.9629164047768697	>1
199	A	N	All mutations	N	2.0345694531741043	>1
199	A	C	All mutations	C	2.0320553111250788	>1
199	A	A	All mutations	A	0.0069138906348208675	1
199	A	E	All mutations	E	1.9685732243871779	>1
199	A	Y	All mutations	Y	2.0339409176618477	>1
199	A	K	All mutations	K	2.961659333752357	>1
199	A	P	All mutations	P	1.0012570710245128	1
199	A	G	All mutations	G	1.0031426775612822	1
199	A	S	All mutations	S	0.9962287869264613	1
199	A	I	All mutations	I	1.9981143934632306	>1
199	A	V	All mutations	V	1.0050282840980516	1
199	A	F	All mutations	F	2.0339409176618477	>1
199	A	D	All mutations	D	1.0414833438089253	1
199	A	H	All mutations	H	2.035826524198617	>1
199	A	R	All mutations	R	1.9974858579509742	>1
199	A	M	All mutations	M	2.9981143934632306	>1
199	A	L	All mutations	L	1.9993714644877436	>1
199	A	T	All mutations	T	1.0	1
199	A	W	All mutations	W	2.995600251414205	>1
200	P	G	All mutations	G	2.0	>1
200	P	E	All mutations	E	2.9164047768698933	>1
200	P	T	All mutations	T	1.0	1
200	P	H	All mutations	H	1.083595223130107	1
200	P	Y	All mutations	Y	2.0835952231301067	>1
200	P	L	All mutations	L	1.0	1
200	P	A	All mutations	A	1.0	1
200	P	N	All mutations	N	2.0835952231301067	>1
200	P	C	All mutations	C	2.0835952231301067	>1
200	P	Q	All mutations	Q	1.916404776869893	>1
200	P	V	All mutations	V	2.0	>1
200	P	W	All mutations	W	2.9937146448774357	>1
200	P	P	All mutations	P	0.0	0
200	P	K	All mutations	K	2.9164047768698933	>1
200	P	F	All mutations	F	2.0835952231301067	>1
200	P	S	All mutations	S	1.0	1
200	P	I	All mutations	I	2.0062853551225643	>1
200	P	D	All mutations	D	2.0835952231301067	>1
200	P	M	All mutations	M	2.9937146448774357	>1
200	P	R	All mutations	R	1.0	1
201	L	V	All mutations	V	1.0	1
201	L	R	All mutations	R	1.6304211187932118	>1
201	L	S	All mutations	S	1.3695788812067882	>1
201	L	L	All mutations	L	0.0	0
201	L	A	All mutations	A	2.0	>1
201	L	E	All mutations	E	2.0050282840980516	>1
201	L	Y	All mutations	Y	2.3645505971087366	>1
201	L	F	All mutations	F	1.3645505971087366	>1
201	L	M	All mutations	M	1.4085480829666877	>1
201	L	D	All mutations	D	2.9949717159019484	>1
201	L	C	All mutations	C	2.3645505971087366	>1
201	L	P	All mutations	P	1.6304211187932118	>1
201	L	W	All mutations	W	1.7781269641734758	>1
201	L	K	All mutations	K	2.0050282840980516	>1
201	L	N	All mutations	N	2.9949717159019484	>1
201	L	I	All mutations	I	1.5914519170333123	>1
201	L	Q	All mutations	Q	1.6354494028912634	>1
201	L	G	All mutations	G	2.0	>1
201	L	H	All mutations	H	2.6253928346951603	>1
201	L	T	All mutations	T	2.0	>1
202	M	H	All mutations	H	3.0	>1
202	M	A	All mutations	A	2.0	>1
202	M	K	All mutations	K	1.0	1
202	M	W	All mutations	W	2.0	>1
202	M	N	All mutations	N	2.0	>1
202	M	D	All mutations	D	3.0	>1
202	M	F	All mutations	F	2.0	>1
202	M	V	All mutations	V	1.0	1
202	M	R	All mutations	R	1.0	1
202	M	T	All mutations	T	1.0	1
202	M	M	All mutations	M	0.0	0
202	M	P	All mutations	P	2.0	>1
202	M	S	All mutations	S	2.0	>1
202	M	G	All mutations	G	2.0	>1
202	M	E	All mutations	E	2.0	>1
202	M	C	All mutations	C	3.0	>1
202	M	Q	All mutations	Q	2.0	>1
202	M	I	All mutations	I	1.0	1
202	M	L	All mutations	L	1.0	1
202	M	Y	All mutations	Y	3.0	>1
203	V	T	All mutations	T	1.9962287869264614	>1
203	V	E	All mutations	E	1.5367693274670018	>1
203	V	Q	All mutations	Q	2.5329981143934632	>1
203	V	W	All mutations	W	2.544311753614079	>1
203	V	N	All mutations	N	2.463230672532998	>1
203	V	V	All mutations	V	0.003771213073538655	1
203	V	C	All mutations	C	2.4670018856065368	>1
203	V	M	All mutations	M	1.5405405405405406	>1
203	V	D	All mutations	D	1.4707730986800753	>1
203	V	K	All mutations	K	2.5292269013199244	>1
203	V	I	All mutations	I	1.451917033312382	>1
203	V	P	All mutations	P	2.0	>1
203	V	F	All mutations	F	1.4670018856065368	>1
203	V	H	All mutations	H	2.4670018856065368	>1
203	V	Y	All mutations	Y	2.4670018856065368	>1
203	V	R	All mutations	R	1.9962287869264614	>1
203	V	G	All mutations	G	1.0037712130735386	1
203	V	S	All mutations	S	2.0	>1
203	V	A	All mutations	A	1.0037712130735386	1
203	V	L	All mutations	L	1.0	1
204	A	T	All mutations	T	1.0	1
204	A	F	All mutations	F	2.9352608422375863	>1
204	A	M	All mutations	M	2.9905719673161535	>1
204	A	S	All mutations	S	1.0	1
204	A	V	All mutations	V	1.0	1
204	A	Q	All mutations	Q	2.0647391577624137	>1
204	A	L	All mutations	L	2.0	>1
204	A	H	All mutations	H	2.9352608422375863	>1
204	A	W	All mutations	W	2.9905719673161535	>1
204	A	E	All mutations	E	1.0647391577624137	1
204	A	D	All mutations	D	1.9352608422375863	>1
204	A	R	All mutations	R	2.0	>1
204	A	K	All mutations	K	2.0647391577624137	>1
204	A	A	All mutations	A	0.0	0
204	A	G	All mutations	G	1.0	1
204	A	Y	All mutations	Y	2.9352608422375863	>1
204	A	P	All mutations	P	1.0	1
204	A	I	All mutations	I	2.0094280326838465	>1
204	A	N	All mutations	N	2.9352608422375863	>1
204	A	C	All mutations	C	2.9352608422375863	>1
205	Y	H	All mutations	H	1.0	1
205	Y	L	All mutations	L	2.0	>1
205	Y	W	All mutations	W	2.0	>1
205	Y	C	All mutations	C	1.0	1
205	Y	N	All mutations	N	1.0	1
205	Y	Q	All mutations	Q	2.0	>1
205	Y	S	All mutations	S	1.0	1
205	Y	A	All mutations	A	2.0	>1
205	Y	R	All mutations	R	2.0	>1
205	Y	I	All mutations	I	2.0	>1
205	Y	G	All mutations	G	2.0	>1
205	Y	T	All mutations	T	2.0	>1
205	Y	V	All mutations	V	2.0	>1
205	Y	K	All mutations	K	2.0	>1
205	Y	Y	All mutations	Y	0.0	0
205	Y	M	All mutations	M	3.0	>1
205	Y	E	All mutations	E	2.0	>1
205	Y	F	All mutations	F	1.0	1
205	Y	D	All mutations	D	1.0	1
205	Y	P	All mutations	P	2.0	>1
206	M	M	All mutations	M	0.0	0
206	M	P	All mutations	P	2.0	>1
206	M	Y	All mutations	Y	3.0	>1
206	M	E	All mutations	E	2.0	>1
206	M	G	All mutations	G	2.0	>1
206	M	Q	All mutations	Q	2.0	>1
206	M	R	All mutations	R	1.0	1
206	M	C	All mutations	C	3.0	>1
206	M	S	All mutations	S	2.0	>1
206	M	L	All mutations	L	1.0	1
206	M	T	All mutations	T	1.0	1
206	M	D	All mutations	D	3.0	>1
206	M	A	All mutations	A	2.0	>1
206	M	W	All mutations	W	2.0	>1
206	M	F	All mutations	F	2.0	>1
206	M	K	All mutations	K	1.0	1
206	M	I	All mutations	I	1.0	1
206	M	V	All mutations	V	1.0	1
206	M	H	All mutations	H	3.0	>1
206	M	N	All mutations	N	2.0	>1
207	L	I	All mutations	I	1.5399120050282842	>1
207	L	L	All mutations	L	0.0	0
207	L	W	All mutations	W	1.9113764927718415	>1
207	L	K	All mutations	K	2.0006285355122566	>1
207	L	M	All mutations	M	1.4600879949717158	>1
207	L	P	All mutations	P	1.5487115021998743	>1
207	L	H	All mutations	H	2.548082966687618	>1
207	L	N	All mutations	N	2.9993714644877434	>1
207	L	T	All mutations	T	2.0	>1
207	L	C	All mutations	C	2.4506599622878693	>1
207	L	V	All mutations	V	1.0	1
207	L	G	All mutations	G	2.0	>1
207	L	F	All mutations	F	1.4506599622878693	>1
207	L	R	All mutations	R	1.5487115021998743	>1
207	L	E	All mutations	E	2.0006285355122566	>1
207	L	A	All mutations	A	2.0	>1
207	L	S	All mutations	S	1.4512884978001257	>1
207	L	Q	All mutations	Q	1.5493400377121307	>1
207	L	D	All mutations	D	2.9993714644877434	>1
207	L	Y	All mutations	Y	2.4506599622878693	>1
208	E	C	All mutations	C	3.0	>1
208	E	T	All mutations	T	2.0	>1
208	E	H	All mutations	H	2.0	>1
208	E	V	All mutations	V	1.0	1
208	E	R	All mutations	R	2.0	>1
208	E	E	All mutations	E	0.0	0
208	E	M	All mutations	M	2.6913890634820867	>1
208	E	Y	All mutations	Y	2.0	>1
208	E	P	All mutations	P	2.0	>1
208	E	G	All mutations	G	1.0	1
208	E	N	All mutations	N	2.0	>1
208	E	I	All mutations	I	2.3086109365179133	>1
208	E	A	All mutations	A	1.0	1
208	E	F	All mutations	F	3.0	>1
208	E	Q	All mutations	Q	1.0	1
208	E	K	All mutations	K	1.0	1
208	E	L	All mutations	L	2.0	>1
208	E	D	All mutations	D	1.0	1
208	E	W	All mutations	W	2.6913890634820867	>1
208	E	S	All mutations	S	2.0	>1
209	R	F	All mutations	F	2.9993714644877434	>1
209	R	T	All mutations	T	1.0	1
209	R	S	All mutations	S	0.9993714644877436	1
209	R	V	All mutations	V	2.0	>1
209	R	R	All mutations	R	0.0006285355122564425	1
209	R	E	All mutations	E	2.0006285355122566	>1
209	R	M	All mutations	M	1.8359522313010685	>1
209	R	Y	All mutations	Y	2.9993714644877434	>1
209	R	G	All mutations	G	1.0	1
209	R	P	All mutations	P	2.0	>1
209	R	I	All mutations	I	1.1640477686989315	>1
209	R	A	All mutations	A	2.0	>1
209	R	K	All mutations	K	1.0006285355122564	1
209	R	Q	All mutations	Q	2.0006285355122566	>1
209	R	D	All mutations	D	2.9993714644877434	>1
209	R	C	All mutations	C	1.9993714644877436	>1
209	R	N	All mutations	N	1.9993714644877436	>1
209	R	H	All mutations	H	2.9993714644877434	>1
209	R	L	All mutations	L	2.0	>1
209	R	W	All mutations	W	1.8359522313010685	>1
210	E	T	All mutations	T	2.0	>1
210	E	E	All mutations	E	0.0	0
210	E	M	All mutations	M	2.5631678189817726	>1
210	E	W	All mutations	W	2.5631678189817726	>1
210	E	L	All mutations	L	2.0	>1
210	E	P	All mutations	P	2.0	>1
210	E	S	All mutations	S	2.0	>1
210	E	F	All mutations	F	3.0	>1
210	E	D	All mutations	D	1.0	1
210	E	K	All mutations	K	1.0	1
210	E	I	All mutations	I	2.4368321810182274	>1
210	E	C	All mutations	C	3.0	>1
210	E	H	All mutations	H	2.0	>1
210	E	G	All mutations	G	1.0	1
210	E	V	All mutations	V	1.0	1
210	E	Q	All mutations	Q	1.0	1
210	E	R	All mutations	R	2.0	>1
210	E	N	All mutations	N	2.0	>1
210	E	Y	All mutations	Y	2.0	>1
210	E	A	All mutations	A	1.0	1
211	L	G	All mutations	G	2.0	>1
211	L	P	All mutations	P	1.436203645505971	>1
211	L	S	All mutations	S	1.563796354494029	>1
211	L	Y	All mutations	Y	2.5606536769327466	>1
211	L	H	All mutations	H	2.433060967944689	>1
211	L	I	All mutations	I	1.9472030169704588	>1
211	L	T	All mutations	T	2.0	>1
211	L	C	All mutations	C	2.5606536769327466	>1
211	L	N	All mutations	N	2.996857322438718	>1
211	L	K	All mutations	K	2.003142677561282	>1
211	L	D	All mutations	D	2.996857322438718	>1
211	L	L	All mutations	L	0.0	0
211	L	W	All mutations	W	1.6165933375235702	>1
211	L	A	All mutations	A	2.0	>1
211	L	M	All mutations	M	1.0527969830295412	1
211	L	Q	All mutations	Q	1.4393463230672534	>1
211	L	F	All mutations	F	1.5606536769327466	>1
211	L	R	All mutations	R	1.436203645505971	>1
211	L	E	All mutations	E	2.003142677561282	>1
211	L	V	All mutations	V	1.0	1
212	V	C	All mutations	C	2.015713387806411	>1
212	V	R	All mutations	R	2.0	>1
212	V	T	All mutations	T	1.9981143934632306	>1
212	V	I	All mutations	I	1.0043997485857952	1
212	V	Y	All mutations	Y	2.015713387806411	>1
212	V	N	All mutations	N	2.013827781269642	>1
212	V	A	All mutations	A	1.0018856065367694	1
212	V	V	All mutations	V	0.0018856065367693275	1
212	V	S	All mutations	S	1.9981143934632306	>1
212	V	K	All mutations	K	2.9824010056568198	>1
212	V	G	All mutations	G	1.0018856065367694	1
212	V	F	All mutations	F	1.015713387806411	1
212	V	H	All mutations	H	2.015713387806411	>1
212	V	M	All mutations	M	1.9918290383406663	>1
212	V	L	All mutations	L	1.0	1
212	V	P	All mutations	P	2.0	>1
212	V	E	All mutations	E	1.9861722187303583	>1
212	V	Q	All mutations	Q	2.984286612193589	>1
212	V	D	All mutations	D	1.0175989943431805	1
212	V	W	All mutations	W	2.9937146448774357	>1
213	R	D	All mutations	D	2.072281583909491	>1
213	R	H	All mutations	H	1.0798240100565681	1
213	R	T	All mutations	T	1.9924575738529227	>1
213	R	W	All mutations	W	1.9905719673161533	>1
213	R	L	All mutations	L	1.0075424261470773	1
213	R	N	All mutations	N	2.0647391577624137	>1
213	R	A	All mutations	A	2.0	>1
213	R	Q	All mutations	Q	1.9352608422375863	>1
213	R	C	All mutations	C	1.0722815839094908	1
213	R	V	All mutations	V	2.0	>1
213	R	K	All mutations	K	2.9201759899434316	>1
213	R	Y	All mutations	Y	2.072281583909491	>1
213	R	E	All mutations	E	2.927718416090509	>1
213	R	F	All mutations	F	2.072281583909491	>1
213	R	G	All mutations	G	1.0	1
213	R	P	All mutations	P	1.0075424261470773	1
213	R	R	All mutations	R	0.0	0
213	R	S	All mutations	S	1.0647391577624137	1
213	R	M	All mutations	M	2.983029541169076	>1
213	R	I	All mutations	I	2.0018856065367694	>1
214	K	W	All mutations	W	2.544311753614079	>1
214	K	L	All mutations	L	2.0	>1
214	K	S	All mutations	S	1.9968573224387178	>1
214	K	E	All mutations	E	1.0031426775612822	1
214	K	M	All mutations	M	1.5474544311753613	>1
214	K	P	All mutations	P	2.0	>1
214	K	D	All mutations	D	2.003142677561282	>1
214	K	Q	All mutations	Q	1.0031426775612822	1
214	K	H	All mutations	H	2.003142677561282	>1
214	K	F	All mutations	F	3.0	>1
214	K	K	All mutations	K	0.0031426775612822125	1
214	K	A	All mutations	A	2.0	>1
214	K	G	All mutations	G	1.9968573224387178	>1
214	K	V	All mutations	V	2.0	>1
214	K	N	All mutations	N	1.0031426775612822	1
214	K	Y	All mutations	Y	2.003142677561282	>1
214	K	R	All mutations	R	0.9968573224387178	1
214	K	I	All mutations	I	1.4525455688246387	>1
214	K	C	All mutations	C	2.996857322438718	>1
214	K	T	All mutations	T	1.0	1
215	T	A	All mutations	A	1.0	1
215	T	E	All mutations	E	2.3683218101822754	>1
215	T	Y	All mutations	Y	2.6316781898177246	>1
215	T	H	All mutations	H	2.6316781898177246	>1
215	T	M	All mutations	M	1.7335009428032684	>1
215	T	T	All mutations	T	0.0	0
215	T	R	All mutations	R	1.3683218101822754	>1
215	T	G	All mutations	G	2.0	>1
215	T	D	All mutations	D	2.6316781898177246	>1
215	T	P	All mutations	P	1.0	1
215	T	C	All mutations	C	2.6316781898177246	>1
215	T	S	All mutations	S	1.0	1
215	T	W	All mutations	W	2.733500942803268	>1
215	T	V	All mutations	V	2.0	>1
215	T	K	All mutations	K	1.3683218101822754	>1
215	T	Q	All mutations	Q	2.3683218101822754	>1
215	T	F	All mutations	F	2.6316781898177246	>1
215	T	N	All mutations	N	1.6316781898177246	>1
215	T	I	All mutations	I	1.2664990571967316	>1
215	T	L	All mutations	L	2.0	>1
216	R	P	All mutations	P	1.9937146448774357	>1
216	R	L	All mutations	L	1.9937146448774357	>1
216	R	V	All mutations	V	2.0	>1
216	R	M	All mutations	M	1.5361407919547454	>1
216	R	K	All mutations	K	1.0062853551225643	1
216	R	D	All mutations	D	3.0	>1
216	R	H	All mutations	H	2.9937146448774357	>1
216	R	I	All mutations	I	1.4764299182903835	>1
216	R	S	All mutations	S	1.0062853551225643	1
216	R	A	All mutations	A	2.0	>1
216	R	G	All mutations	G	1.0	1
216	R	Y	All mutations	Y	3.0	>1
216	R	E	All mutations	E	2.0	>1
216	R	F	All mutations	F	3.0	>1
216	R	T	All mutations	T	1.0062853551225643	1
216	R	W	All mutations	W	1.529855436832181	>1
216	R	R	All mutations	R	0.0	0
216	R	C	All mutations	C	2.0	>1
216	R	N	All mutations	N	2.0062853551225643	>1
216	R	Q	All mutations	Q	1.9937146448774357	>1
217	F	V	All mutations	V	1.0	1
217	F	F	All mutations	F	0.0	0
217	F	H	All mutations	H	2.0	>1
217	F	W	All mutations	W	2.0	>1
217	F	C	All mutations	C	1.0	1
217	F	P	All mutations	P	2.0	>1
217	F	S	All mutations	S	1.0	1
217	F	G	All mutations	G	2.0	>1
217	F	M	All mutations	M	2.0	>1
217	F	K	All mutations	K	3.0	>1
217	F	L	All mutations	L	1.0	1
217	F	D	All mutations	D	2.0	>1
217	F	I	All mutations	I	1.0	1
217	F	Q	All mutations	Q	3.0	>1
217	F	A	All mutations	A	2.0	>1
217	F	E	All mutations	E	3.0	>1
217	F	Y	All mutations	Y	1.0	1
217	F	R	All mutations	R	2.0	>1
217	F	T	All mutations	T	2.0	>1
217	F	N	All mutations	N	2.0	>1
218	L	P	All mutations	P	1.042740414833438	1
218	L	M	All mutations	M	1.972972972972973	>1
218	L	C	All mutations	C	2.495914519170333	>1
218	L	K	All mutations	K	2.4613450659962286	>1
218	L	G	All mutations	G	2.0	>1
218	L	Y	All mutations	Y	2.495914519170333	>1
218	L	A	All mutations	A	2.0	>1
218	L	I	All mutations	I	1.027027027027027	1
218	L	T	All mutations	T	2.0	>1
218	L	S	All mutations	S	1.957259585166562	>1
218	L	N	All mutations	N	2.5386549340037714	>1
218	L	Q	All mutations	Q	1.5040854808296669	>1
218	L	R	All mutations	R	1.042740414833438	1
218	L	L	All mutations	L	0.0	0
218	L	E	All mutations	E	2.4613450659962286	>1
218	L	D	All mutations	D	2.5386549340037714	>1
218	L	H	All mutations	H	1.5813953488372092	>1
218	L	F	All mutations	F	1.4959145191703331	>1
218	L	W	All mutations	W	2.9302325581395348	>1
218	L	V	All mutations	V	1.0	1
219	P	R	All mutations	R	1.0	1
219	P	S	All mutations	S	1.0	1
219	P	G	All mutations	G	2.0	>1
219	P	E	All mutations	E	2.0276555625392834	>1
219	P	I	All mutations	I	2.1099937146448773	>1
219	P	L	All mutations	L	1.0	1
219	P	K	All mutations	K	2.0276555625392834	>1
219	P	A	All mutations	A	1.0	1
219	P	N	All mutations	N	2.9723444374607166	>1
219	P	H	All mutations	H	1.9723444374607166	>1
219	P	W	All mutations	W	2.8900062853551227	>1
219	P	D	All mutations	D	2.9723444374607166	>1
219	P	C	All mutations	C	2.9723444374607166	>1
219	P	F	All mutations	F	2.9723444374607166	>1
219	P	Q	All mutations	Q	1.0276555625392834	1
219	P	M	All mutations	M	2.8900062853551227	>1
219	P	V	All mutations	V	2.0	>1
219	P	T	All mutations	T	1.0	1
219	P	Y	All mutations	Y	2.9723444374607166	>1
219	P	P	All mutations	P	0.0	0
220	V	N	All mutations	N	2.8485229415461975	>1
220	V	D	All mutations	D	1.8510370835952232	>1
220	V	V	All mutations	V	0.001257071024512885	1
220	V	F	All mutations	F	1.8497800125707102	>1
220	V	T	All mutations	T	1.9987429289754872	>1
220	V	K	All mutations	K	2.148962916404777	>1
220	V	E	All mutations	E	1.1514770584538025	>1
220	V	G	All mutations	G	1.0012570710245128	1
220	V	A	All mutations	A	1.0012570710245128	1
220	V	L	All mutations	L	1.0	1
220	V	P	All mutations	P	2.0	>1
220	V	I	All mutations	I	1.4242614707730987	>1
220	V	Y	All mutations	Y	2.8497800125707102	>1
220	V	H	All mutations	H	2.8497800125707102	>1
220	V	Q	All mutations	Q	2.1502199874292898	>1
220	V	M	All mutations	M	1.5732243871778755	>1
220	V	R	All mutations	R	1.9993714644877436	>1
220	V	C	All mutations	C	2.8497800125707102	>1
220	V	W	All mutations	W	2.5744814582023885	>1
220	V	S	All mutations	S	1.9993714644877436	>1
221	A	Y	All mutations	Y	2.2036455059710875	>1
221	A	T	All mutations	T	0.9836580766813325	1
221	A	E	All mutations	E	1.818353236957888	>1
221	A	D	All mutations	D	1.2369578881206789	>1
221	A	Q	All mutations	Q	2.790069138906348	>1
221	A	V	All mutations	V	1.0219987429289754	1
221	A	N	All mutations	N	2.1854179761156507	>1
221	A	P	All mutations	P	1.006913890634821	1
221	A	H	All mutations	H	2.208673790069139	>1
221	A	W	All mutations	W	2.9949717159019484	>1
221	A	M	All mutations	M	2.9704588309239472	>1
221	A	C	All mutations	C	2.2042740414833437	>1
221	A	A	All mutations	A	0.03519798868636078	1
221	A	S	All mutations	S	1.0018856065367694	1
221	A	F	All mutations	F	2.1979886863607794	>1
221	A	L	All mutations	L	1.9905719673161533	>1
221	A	K	All mutations	K	2.7668133249528597	>1
221	A	R	All mutations	R	1.9993714644877436	>1
221	A	G	All mutations	G	1.02828409805154	1
221	A	I	All mutations	I	1.9704588309239472	>1
222	G	I	All mutations	I	2.007542426147077	>1
222	G	F	All mutations	F	2.0986800754242614	>1
222	G	M	All mutations	M	2.992457573852923	>1
222	G	C	All mutations	C	1.099308610936518	1
222	G	Q	All mutations	Q	2.9013199245757386	>1
222	G	E	All mutations	E	1.9013199245757386	>1
222	G	P	All mutations	P	1.9993714644877436	>1
222	G	G	All mutations	G	0.0006285355122564425	1
222	G	V	All mutations	V	1.0	1
222	G	S	All mutations	S	1.0986800754242614	1
222	G	R	All mutations	R	1.0006285355122564	1
222	G	A	All mutations	A	0.9993714644877436	1
222	G	Y	All mutations	Y	2.0986800754242614	>1
222	G	H	All mutations	H	2.0986800754242614	>1
222	G	W	All mutations	W	1.993086109365179	>1
222	G	N	All mutations	N	2.0986800754242614	>1
222	G	T	All mutations	T	1.9993714644877436	>1
222	G	K	All mutations	K	2.9013199245757386	>1
222	G	D	All mutations	D	1.0986800754242614	1
222	G	L	All mutations	L	2.0	>1
223	G	L	All mutations	L	2.0	>1
223	G	N	All mutations	N	2.9415461973601507	>1
223	G	K	All mutations	K	2.057196731615336	>1
223	G	T	All mutations	T	2.0	>1
223	G	I	All mutations	I	2.4211187932118166	>1
223	G	M	All mutations	M	2.5788812067881834	>1
223	G	P	All mutations	P	2.0	>1
223	G	S	All mutations	S	1.9421747328724073	>1
223	G	C	All mutations	C	1.9428032683846637	>1
223	G	H	All mutations	H	2.9415461973601507	>1
223	G	W	All mutations	W	1.57950974230044	>1
223	G	V	All mutations	V	1.0	1
223	G	G	All mutations	G	0.0006285355122564425	1
223	G	Y	All mutations	Y	2.9415461973601507	>1
223	G	F	All mutations	F	2.9421747328724073	>1
223	G	D	All mutations	D	1.9415461973601509	>1
223	G	R	All mutations	R	1.0006285355122564	1
223	G	Q	All mutations	Q	2.057196731615336	>1
223	G	A	All mutations	A	1.0	1
223	G	E	All mutations	E	1.0571967316153363	1
224	T	W	All mutations	W	2.977372721558768	>1
224	T	S	All mutations	S	1.0006285355122564	1
224	T	D	All mutations	D	2.9981143934632306	>1
224	T	A	All mutations	A	1.0006285355122564	1
224	T	M	All mutations	M	1.9767441860465116	>1
224	T	I	All mutations	I	1.0219987429289754	1
224	T	Q	All mutations	Q	2.0018856065367694	>1
224	T	V	All mutations	V	1.9993714644877436	>1
224	T	N	All mutations	N	1.9981143934632306	>1
224	T	P	All mutations	P	1.0006285355122564	1
224	T	F	All mutations	F	2.9974858579509744	>1
224	T	K	All mutations	K	1.0018856065367694	1
224	T	E	All mutations	E	2.0018856065367694	>1
224	T	R	All mutations	R	1.0018856065367694	1
224	T	H	All mutations	H	2.9981143934632306	>1
224	T	G	All mutations	G	2.0	>1
224	T	T	All mutations	T	0.0006285355122564425	1
224	T	L	All mutations	L	1.9993714644877436	>1
224	T	Y	All mutations	Y	2.9981143934632306	>1
224	T	C	All mutations	C	2.9981143934632306	>1
225	S	C	All mutations	C	1.0	1
225	S	R	All mutations	R	1.0	1
225	S	V	All mutations	V	1.9962287869264614	>1
225	S	Q	All mutations	Q	3.0	>1
225	S	D	All mutations	D	1.9962287869264614	>1
225	S	M	All mutations	M	2.003771213073539	>1
225	S	W	All mutations	W	2.0	>1
225	S	E	All mutations	E	2.996228786926461	>1
225	S	L	All mutations	L	2.0	>1
225	S	P	All mutations	P	2.0	>1
225	S	H	All mutations	H	2.0	>1
225	S	N	All mutations	N	1.0037712130735386	1
225	S	T	All mutations	T	1.0037712130735386	1
225	S	S	All mutations	S	0.003771213073538655	1
225	S	Y	All mutations	Y	2.0	>1
225	S	F	All mutations	F	2.0	>1
225	S	A	All mutations	A	1.9962287869264614	>1
225	S	G	All mutations	G	0.9962287869264613	1
225	S	I	All mutations	I	1.0037712130735386	1
225	S	K	All mutations	K	2.003771213073539	>1
226	S	G	All mutations	G	1.0006285355122564	1
226	S	E	All mutations	E	2.9993714644877434	>1
226	S	A	All mutations	A	2.0	>1
226	S	V	All mutations	V	2.0	>1
226	S	Y	All mutations	Y	1.9993714644877436	>1
226	S	T	All mutations	T	1.0	1
226	S	P	All mutations	P	2.0	>1
226	S	F	All mutations	F	2.0	>1
226	S	M	All mutations	M	2.0	>1
226	S	C	All mutations	C	1.0006285355122564	1
226	S	I	All mutations	I	1.0	1
226	S	S	All mutations	S	0.0006285355122564425	1
226	S	W	All mutations	W	2.0006285355122566	>1
226	S	K	All mutations	K	1.9993714644877436	>1
226	S	N	All mutations	N	0.9993714644877436	1
226	S	H	All mutations	H	1.9993714644877436	>1
226	S	Q	All mutations	Q	2.9993714644877434	>1
226	S	L	All mutations	L	2.0	>1
226	S	D	All mutations	D	1.9993714644877436	>1
226	S	R	All mutations	R	1.0006285355122564	1
227	V	T	All mutations	T	1.9956002514142048	>1
227	V	V	All mutations	V	0.0043997485857950975	1
227	V	W	All mutations	W	2.5637963544940288	>1
227	V	K	All mutations	K	2.474544311753614	>1
227	V	R	All mutations	R	1.9987429289754872	>1
227	V	G	All mutations	G	1.0043997485857952	1
227	V	I	All mutations	I	1.431803896920176	>1
227	V	E	All mutations	E	1.4833438089252042	>1
227	V	L	All mutations	L	1.0	1
227	V	C	All mutations	C	2.5210559396605907	>1
227	V	H	All mutations	H	2.5210559396605907	>1
227	V	Y	All mutations	Y	2.5210559396605907	>1
227	V	P	All mutations	P	2.0	>1
227	V	F	All mutations	F	1.5210559396605907	>1
227	V	Q	All mutations	Q	2.4789440603394093	>1
227	V	M	All mutations	M	1.5593966059082338	>1
227	V	D	All mutations	D	1.5254556882463859	>1
227	V	A	All mutations	A	1.0043997485857952	1
227	V	N	All mutations	N	2.5166561910747958	>1
227	V	S	All mutations	S	1.9968573224387178	>1
228	Y	D	All mutations	D	1.0	1
228	Y	Y	All mutations	Y	0.0	0
228	Y	F	All mutations	F	1.0	1
228	Y	R	All mutations	R	2.0	>1
228	Y	C	All mutations	C	1.0	1
228	Y	E	All mutations	E	2.0	>1
228	Y	Q	All mutations	Q	2.0	>1
228	Y	T	All mutations	T	2.0	>1
228	Y	G	All mutations	G	2.0	>1
228	Y	K	All mutations	K	2.0	>1
228	Y	I	All mutations	I	2.0	>1
228	Y	P	All mutations	P	2.0	>1
228	Y	N	All mutations	N	1.0	1
228	Y	W	All mutations	W	2.0	>1
228	Y	M	All mutations	M	3.0	>1
228	Y	A	All mutations	A	2.0	>1
228	Y	L	All mutations	L	2.0	>1
228	Y	S	All mutations	S	1.0	1
228	Y	V	All mutations	V	2.0	>1
228	Y	H	All mutations	H	1.0	1
229	I	S	All mutations	S	1.0879949717159019	1
229	I	F	All mutations	F	1.085480829666876	1
229	I	P	All mutations	P	2.0	>1
229	I	N	All mutations	N	1.0879949717159019	1
229	I	H	All mutations	H	2.085480829666876	>1
229	I	L	All mutations	L	1.0	1
229	I	Q	All mutations	Q	2.914519170333124	>1
229	I	A	All mutations	A	1.9974858579509742	>1
229	I	G	All mutations	G	1.9974858579509742	>1
229	I	W	All mutations	W	3.0	>1
229	I	E	All mutations	E	2.912005028284098	>1
229	I	C	All mutations	C	2.085480829666876	>1
229	I	I	All mutations	I	0.00251414204902577	1
229	I	D	All mutations	D	2.0829666876178505	>1
229	I	M	All mutations	M	1.0025141420490258	1
229	I	V	All mutations	V	0.9974858579509742	1
229	I	R	All mutations	R	1.914519170333124	>1
229	I	Y	All mutations	Y	2.085480829666876	>1
229	I	K	All mutations	K	1.9170333123821497	>1
229	I	T	All mutations	T	1.0025141420490258	1
230	E	C	All mutations	C	3.0	>1
230	E	D	All mutations	D	1.0	1
230	E	M	All mutations	M	2.2608422375864237	>1
230	E	N	All mutations	N	2.0	>1
230	E	H	All mutations	H	2.0	>1
230	E	V	All mutations	V	1.0	1
230	E	S	All mutations	S	2.0	>1
230	E	P	All mutations	P	2.0	>1
230	E	A	All mutations	A	1.0	1
230	E	W	All mutations	W	2.2608422375864237	>1
230	E	I	All mutations	I	2.7391577624135763	>1
230	E	F	All mutations	F	3.0	>1
230	E	Q	All mutations	Q	1.0	1
230	E	K	All mutations	K	1.0	1
230	E	G	All mutations	G	1.0	1
230	E	T	All mutations	T	2.0	>1
230	E	Y	All mutations	Y	2.0	>1
230	E	E	All mutations	E	0.0	0
230	E	R	All mutations	R	2.0	>1
230	E	L	All mutations	L	2.0	>1
231	V	M	All mutations	M	1.3475801382778128	>1
231	V	K	All mutations	K	2.010056568196103	>1
231	V	I	All mutations	I	1.6524198617221872	>1
231	V	N	All mutations	N	2.989943431803897	>1
231	V	H	All mutations	H	2.989943431803897	>1
231	V	L	All mutations	L	1.0	1
231	V	S	All mutations	S	2.0	>1
231	V	V	All mutations	V	0.0	0
231	V	T	All mutations	T	2.0	>1
231	V	E	All mutations	E	1.0100565681961031	1
231	V	Q	All mutations	Q	2.010056568196103	>1
231	V	A	All mutations	A	1.0	1
231	V	P	All mutations	P	2.0	>1
231	V	F	All mutations	F	1.9899434318038969	>1
231	V	D	All mutations	D	1.9899434318038969	>1
231	V	C	All mutations	C	2.989943431803897	>1
231	V	R	All mutations	R	2.0	>1
231	V	G	All mutations	G	1.0	1
231	V	Y	All mutations	Y	2.989943431803897	>1
231	V	W	All mutations	W	2.3475801382778125	>1
232	L	W	All mutations	W	1.8447517284726587	>1
232	L	C	All mutations	C	2.610936517913262	>1
232	L	Q	All mutations	Q	1.3884349465744814	>1
232	L	V	All mutations	V	1.0006285355122564	1
232	L	P	All mutations	P	1.3632935260842238	>1
232	L	T	All mutations	T	2.0	>1
232	L	I	All mutations	I	1.792583280955374	>1
232	L	Y	All mutations	Y	2.6103079824010056	>1
232	L	E	All mutations	E	2.025141420490258	>1
232	L	H	All mutations	H	2.3368950345694532	>1
232	L	S	All mutations	S	1.6367064739157762	>1
232	L	F	All mutations	F	1.6115650534255186	>1
232	L	L	All mutations	L	0.001257071024512885	1
232	L	N	All mutations	N	2.9736015084852294	>1
232	L	R	All mutations	R	1.3632935260842238	>1
232	L	G	All mutations	G	2.0	>1
232	L	M	All mutations	M	1.2086737900691389	>1
232	L	K	All mutations	K	2.025141420490258	>1
232	L	D	All mutations	D	2.9736015084852294	>1
232	L	A	All mutations	A	2.0	>1
233	H	C	All mutations	C	2.0	>1
233	H	N	All mutations	N	1.0	1
233	H	M	All mutations	M	3.0	>1
233	H	P	All mutations	P	1.0	1
233	H	G	All mutations	G	2.0	>1
233	H	Q	All mutations	Q	1.0	1
233	H	K	All mutations	K	2.0	>1
233	H	D	All mutations	D	1.0	1
233	H	A	All mutations	A	2.0	>1
233	H	H	All mutations	H	0.0	0
233	H	W	All mutations	W	3.0	>1
233	H	F	All mutations	F	2.0	>1
233	H	Y	All mutations	Y	1.0	1
233	H	I	All mutations	I	2.0	>1
233	H	E	All mutations	E	2.0	>1
233	H	S	All mutations	S	2.0	>1
233	H	L	All mutations	L	1.0	1
233	H	R	All mutations	R	1.0	1
233	H	T	All mutations	T	2.0	>1
233	H	V	All mutations	V	2.0	>1
234	L	W	All mutations	W	1.1910747957259584	>1
234	L	R	All mutations	R	1.9528598365807668	>1
234	L	Q	All mutations	Q	1.9534883720930232	>1
234	L	V	All mutations	V	1.0	1
234	L	C	All mutations	C	2.047140163419233	>1
234	L	H	All mutations	H	2.9522313010685104	>1
234	L	D	All mutations	D	2.9993714644877434	>1
234	L	F	All mutations	F	1.0471401634192332	1
234	L	I	All mutations	I	1.8560653676932746	>1
234	L	E	All mutations	E	2.0006285355122566	>1
234	L	S	All mutations	S	1.0471401634192332	1
234	L	T	All mutations	T	1.9993714644877436	>1
234	L	N	All mutations	N	2.998742928975487	>1
234	L	M	All mutations	M	1.1426775612822124	>1
234	L	L	All mutations	L	0.0006285355122564425	1
234	L	P	All mutations	P	1.9528598365807668	>1
234	L	A	All mutations	A	2.0	>1
234	L	K	All mutations	K	2.0	>1
234	L	Y	All mutations	Y	2.047140163419233	>1
234	L	G	All mutations	G	2.0	>1
235	T	I	All mutations	I	1.0012570710245128	1
235	T	E	All mutations	E	2.993086109365179	>1
235	T	Q	All mutations	Q	2.9937146448774357	>1
235	T	L	All mutations	L	2.0	>1
235	T	N	All mutations	N	1.005656819610308	1
235	T	V	All mutations	V	1.9993714644877436	>1
235	T	P	All mutations	P	1.0006285355122564	1
235	T	T	All mutations	T	0.001257071024512885	1
235	T	Y	All mutations	Y	2.0050282840980516	>1
235	T	G	All mutations	G	1.9993714644877436	>1
235	T	K	All mutations	K	1.994343180389692	>1
235	T	D	All mutations	D	2.004399748585795	>1
235	T	F	All mutations	F	2.005656819610308	>1
235	T	S	All mutations	S	1.0006285355122564	1
235	T	M	All mutations	M	2.0	>1
235	T	H	All mutations	H	2.0050282840980516	>1
235	T	C	All mutations	C	2.005656819610308	>1
235	T	W	All mutations	W	2.9993714644877434	>1
235	T	A	All mutations	A	1.0	1
235	T	R	All mutations	R	1.994343180389692	>1
236	Q	M	All mutations	M	2.5304839723444377	>1
236	Q	Y	All mutations	Y	2.0	>1
236	Q	K	All mutations	K	1.0006285355122564	1
236	Q	A	All mutations	A	1.9993714644877436	>1
236	Q	W	All mutations	W	2.531112507856694	>1
236	Q	R	All mutations	R	1.0	1
236	Q	H	All mutations	H	1.0006285355122564	1
236	Q	I	All mutations	I	2.4682589566310495	>1
236	Q	F	All mutations	F	2.9993714644877434	>1
236	Q	P	All mutations	P	1.0	1
236	Q	D	All mutations	D	2.0	>1
236	Q	E	All mutations	E	1.0012570710245128	1
236	Q	V	All mutations	V	2.0	>1
236	Q	T	All mutations	T	1.9987429289754872	>1
236	Q	C	All mutations	C	2.9993714644877434	>1
236	Q	G	All mutations	G	2.0	>1
236	Q	S	All mutations	S	1.9993714644877436	>1
236	Q	L	All mutations	L	1.0006285355122564	1
236	Q	Q	All mutations	Q	0.0018856065367693275	1
236	Q	N	All mutations	N	1.9993714644877436	>1
237	G	N	All mutations	N	2.9893148962916403	>1
237	G	S	All mutations	S	1.9893148962916405	>1
237	G	Y	All mutations	Y	2.989943431803897	>1
237	G	A	All mutations	A	1.0006285355122564	1
237	G	I	All mutations	I	2.7234443746071655	>1
237	G	P	All mutations	P	2.0	>1
237	G	W	All mutations	W	1.2759270898805783	>1
237	G	G	All mutations	G	0.0006285355122564425	1
237	G	K	All mutations	K	2.0094280326838465	>1
237	G	M	All mutations	M	2.2752985543683217	>1
237	G	R	All mutations	R	0.9993714644877436	1
237	G	F	All mutations	F	2.989943431803897	>1
237	G	Q	All mutations	Q	2.010056568196103	>1
237	G	H	All mutations	H	2.989943431803897	>1
237	G	E	All mutations	E	1.0106851037083595	1
237	G	L	All mutations	L	2.0	>1
237	G	V	All mutations	V	1.0006285355122564	1
237	G	C	All mutations	C	1.9899434318038969	>1
237	G	T	All mutations	T	1.9993714644877436	>1
237	G	D	All mutations	D	1.9905719673161533	>1
238	T	I	All mutations	I	1.0100565681961031	1
238	T	L	All mutations	L	2.0	>1
238	T	K	All mutations	K	1.5493400377121307	>1
238	T	D	All mutations	D	2.4494028912633565	>1
238	T	C	All mutations	C	2.451288497800126	>1
238	T	F	All mutations	F	2.451288497800126	>1
238	T	S	All mutations	S	1.0006285355122564	1
238	T	G	All mutations	G	1.9987429289754872	>1
238	T	Y	All mutations	Y	2.4506599622878693	>1
238	T	Q	All mutations	Q	2.548082966687618	>1
238	T	W	All mutations	W	2.9912005028284097	>1
238	T	N	All mutations	N	1.451917033312382	>1
238	T	V	All mutations	V	1.9987429289754872	>1
238	T	P	All mutations	P	1.0006285355122564	1
238	T	H	All mutations	H	2.4506599622878693	>1
238	T	E	All mutations	E	2.546825895663105	>1
238	T	R	All mutations	R	1.5487115021998743	>1
238	T	A	All mutations	A	0.9993714644877436	1
238	T	M	All mutations	M	1.9924575738529227	>1
238	T	T	All mutations	T	0.0018856065367693275	1
239	C	T	All mutations	T	2.0	>1
239	C	G	All mutations	G	1.0	1
239	C	S	All mutations	S	1.0	1
239	C	E	All mutations	E	3.0	>1
239	C	F	All mutations	F	1.0	1
239	C	I	All mutations	I	2.0	>1
239	C	N	All mutations	N	2.0	>1
239	C	W	All mutations	W	1.0	1
239	C	H	All mutations	H	2.0	>1
239	C	V	All mutations	V	2.0	>1
239	C	C	All mutations	C	0.0	0
239	C	R	All mutations	R	1.0	1
239	C	Y	All mutations	Y	1.0	1
239	C	M	All mutations	M	3.0	>1
239	C	D	All mutations	D	2.0	>1
239	C	K	All mutations	K	3.0	>1
239	C	P	All mutations	P	2.0	>1
239	C	A	All mutations	A	2.0	>1
239	C	L	All mutations	L	2.0	>1
239	C	Q	All mutations	Q	3.0	>1
240	W	E	All mutations	E	2.0	>1
240	W	H	All mutations	H	3.0	>1
240	W	A	All mutations	A	2.0	>1
240	W	N	All mutations	N	3.0	>1
240	W	W	All mutations	W	0.0	0
240	W	R	All mutations	R	1.0	1
240	W	K	All mutations	K	2.0	>1
240	W	G	All mutations	G	1.0	1
240	W	T	All mutations	T	2.0	>1
240	W	Q	All mutations	Q	2.0	>1
240	W	V	All mutations	V	2.0	>1
240	W	S	All mutations	S	1.0	1
240	W	L	All mutations	L	1.0	1
240	W	M	All mutations	M	2.0	>1
240	W	F	All mutations	F	2.0	>1
240	W	D	All mutations	D	3.0	>1
240	W	I	All mutations	I	3.0	>1
240	W	P	All mutations	P	2.0	>1
240	W	C	All mutations	C	1.0	1
240	W	Y	All mutations	Y	2.0	>1
241	E	G	All mutations	G	1.0	1
241	E	P	All mutations	P	2.0	>1
241	E	N	All mutations	N	2.0	>1
241	E	F	All mutations	F	3.0	>1
241	E	R	All mutations	R	2.0	>1
241	E	S	All mutations	S	2.0	>1
241	E	I	All mutations	I	2.629164047768699	>1
241	E	Q	All mutations	Q	1.0	1
241	E	Y	All mutations	Y	2.0	>1
241	E	M	All mutations	M	2.370835952231301	>1
241	E	A	All mutations	A	1.0	1
241	E	L	All mutations	L	2.0	>1
241	E	V	All mutations	V	1.0	1
241	E	H	All mutations	H	2.0	>1
241	E	T	All mutations	T	2.0	>1
241	E	K	All mutations	K	1.0	1
241	E	E	All mutations	E	0.0	0
241	E	W	All mutations	W	2.370835952231301	>1
241	E	C	All mutations	C	3.0	>1
241	E	D	All mutations	D	1.0	1
242	Q	K	All mutations	K	1.0	1
242	Q	F	All mutations	F	3.0	>1
242	Q	N	All mutations	N	2.0	>1
242	Q	V	All mutations	V	2.0	>1
242	Q	Q	All mutations	Q	0.0	0
242	Q	L	All mutations	L	1.0	1
242	Q	W	All mutations	W	2.480201131363922	>1
242	Q	C	All mutations	C	3.0	>1
242	Q	R	All mutations	R	1.0	1
242	Q	M	All mutations	M	2.480201131363922	>1
242	Q	Y	All mutations	Y	2.0	>1
242	Q	T	All mutations	T	2.0	>1
242	Q	P	All mutations	P	1.0	1
242	Q	E	All mutations	E	1.0	1
242	Q	H	All mutations	H	1.0	1
242	Q	I	All mutations	I	2.519798868636078	>1
242	Q	G	All mutations	G	2.0	>1
242	Q	A	All mutations	A	2.0	>1
242	Q	S	All mutations	S	2.0	>1
242	Q	D	All mutations	D	2.0	>1
243	M	C	All mutations	C	2.9949717159019484	>1
243	M	W	All mutations	W	2.0062853551225643	>1
243	M	E	All mutations	E	2.0050282840980516	>1
243	M	H	All mutations	H	2.9949717159019484	>1
243	M	V	All mutations	V	1.0006285355122564	1
243	M	S	All mutations	S	1.994343180389692	>1
243	M	Y	All mutations	Y	2.9949717159019484	>1
243	M	R	All mutations	R	1.0050282840980516	1
243	M	A	All mutations	A	1.9993714644877436	>1
243	M	K	All mutations	K	1.0050282840980516	1
243	M	G	All mutations	G	2.0	>1
243	M	L	All mutations	L	1.0006285355122564	1
243	M	T	All mutations	T	0.9993714644877436	1
243	M	Q	All mutations	Q	2.0050282840980516	>1
243	M	I	All mutations	I	0.994343180389692	1
243	M	D	All mutations	D	2.9949717159019484	>1
243	M	F	All mutations	F	1.9956002514142048	>1
243	M	M	All mutations	M	0.0069138906348208675	1
243	M	P	All mutations	P	1.9993714644877436	>1
243	M	N	All mutations	N	1.9949717159019484	>1
244	Y	K	All mutations	K	2.0	>1
244	Y	A	All mutations	A	2.0	>1
244	Y	Y	All mutations	Y	0.0	0
244	Y	S	All mutations	S	1.0	1
244	Y	W	All mutations	W	2.0	>1
244	Y	V	All mutations	V	2.0	>1
244	Y	R	All mutations	R	2.0	>1
244	Y	N	All mutations	N	1.0	1
244	Y	L	All mutations	L	2.0	>1
244	Y	E	All mutations	E	2.0	>1
244	Y	M	All mutations	M	3.0	>1
244	Y	D	All mutations	D	1.0	1
244	Y	I	All mutations	I	2.0	>1
244	Y	T	All mutations	T	2.0	>1
244	Y	C	All mutations	C	1.0	1
244	Y	G	All mutations	G	2.0	>1
244	Y	F	All mutations	F	1.0	1
244	Y	P	All mutations	P	2.0	>1
244	Y	Q	All mutations	Q	2.0	>1
244	Y	H	All mutations	H	1.0	1
245	T	C	All mutations	C	2.3249528598365807	>1
245	T	L	All mutations	L	2.0	>1
245	T	M	All mutations	M	1.9880578252671275	>1
245	T	S	All mutations	S	1.0	1
245	T	Q	All mutations	Q	2.6750471401634193	>1
245	T	V	All mutations	V	2.0	>1
245	T	Y	All mutations	Y	2.3249528598365807	>1
245	T	N	All mutations	N	1.3249528598365807	>1
245	T	F	All mutations	F	2.3249528598365807	>1
245	T	E	All mutations	E	2.6750471401634193	>1
245	T	I	All mutations	I	1.0119421747328725	1
245	T	G	All mutations	G	2.0	>1
245	T	D	All mutations	D	2.3249528598365807	>1
245	T	W	All mutations	W	2.9880578252671275	>1
245	T	A	All mutations	A	1.0	1
245	T	P	All mutations	P	1.0	1
245	T	T	All mutations	T	0.0	0
245	T	K	All mutations	K	1.6750471401634193	>1
245	T	H	All mutations	H	2.3249528598365807	>1
245	T	R	All mutations	R	1.6750471401634193	>1
246	P	I	All mutations	I	2.3796354494028913	>1
246	P	K	All mutations	K	2.015713387806411	>1
246	P	E	All mutations	E	2.015713387806411	>1
246	P	T	All mutations	T	1.0	1
246	P	R	All mutations	R	1.0	1
246	P	W	All mutations	W	2.6203645505971087	>1
246	P	H	All mutations	H	1.984286612193589	>1
246	P	Q	All mutations	Q	1.015713387806411	1
246	P	S	All mutations	S	1.0	1
246	P	A	All mutations	A	1.0	1
246	P	C	All mutations	C	2.984286612193589	>1
246	P	M	All mutations	M	2.6203645505971087	>1
246	P	L	All mutations	L	1.0	1
246	P	Y	All mutations	Y	2.984286612193589	>1
246	P	G	All mutations	G	2.0	>1
246	P	V	All mutations	V	2.0	>1
246	P	D	All mutations	D	2.984286612193589	>1
246	P	P	All mutations	P	0.0	0
246	P	N	All mutations	N	2.984286612193589	>1
246	P	F	All mutations	F	2.984286612193589	>1
247	G	Q	All mutations	Q	2.1904462602137023	>1
247	G	N	All mutations	N	2.8095537397862977	>1
247	G	V	All mutations	V	1.0	1
247	G	E	All mutations	E	1.190446260213702	>1
247	G	G	All mutations	G	0.0	0
247	G	I	All mutations	I	2.0087994971715903	>1
247	G	F	All mutations	F	2.8095537397862977	>1
247	G	M	All mutations	M	2.9912005028284097	>1
247	G	W	All mutations	W	1.9912005028284099	>1
247	G	D	All mutations	D	1.809553739786298	>1
247	G	R	All mutations	R	1.0	1
247	G	S	All mutations	S	1.809553739786298	>1
247	G	Y	All mutations	Y	2.8095537397862977	>1
247	G	P	All mutations	P	2.0	>1
247	G	C	All mutations	C	1.809553739786298	>1
247	G	A	All mutations	A	1.0	1
247	G	H	All mutations	H	2.8095537397862977	>1
247	G	T	All mutations	T	2.0	>1
247	G	K	All mutations	K	2.1904462602137023	>1
247	G	L	All mutations	L	2.0	>1
248	G	K	All mutations	K	2.0062853551225643	>1
248	G	Q	All mutations	Q	2.0062853551225643	>1
248	G	N	All mutations	N	2.992457573852923	>1
248	G	A	All mutations	A	1.0	1
248	G	S	All mutations	S	1.993086109365179	>1
248	G	W	All mutations	W	1.6071653048397234	>1
248	G	V	All mutations	V	1.0	1
248	G	F	All mutations	F	2.993086109365179	>1
248	G	R	All mutations	R	1.0006285355122564	1
248	G	T	All mutations	T	2.0	>1
248	G	Y	All mutations	Y	2.992457573852923	>1
248	G	I	All mutations	I	2.393463230672533	>1
248	G	H	All mutations	H	2.992457573852923	>1
248	G	E	All mutations	E	1.0062853551225643	1
248	G	G	All mutations	G	0.0006285355122564425	1
248	G	D	All mutations	D	1.9924575738529227	>1
248	G	C	All mutations	C	1.9937146448774357	>1
248	G	P	All mutations	P	2.0	>1
248	G	M	All mutations	M	2.606536769327467	>1
248	G	L	All mutations	L	2.0	>1
249	E	Y	All mutations	Y	2.0106851037083597	>1
249	E	D	All mutations	D	1.1055939660590823	>1
249	E	I	All mutations	I	2.0320553111250788	>1
249	E	F	All mutations	F	2.9981143934632306	>1
249	E	M	All mutations	M	2.7781269641734756	>1
249	E	A	All mutations	A	1.0949088623507228	1
249	E	H	All mutations	H	2.0106851037083597	>1
249	E	R	All mutations	R	1.8925204274041483	>1
249	E	T	All mutations	T	1.9050911376492772	>1
249	E	E	All mutations	E	0.10936517913262099	1
249	E	Q	All mutations	Q	1.014456316781898	1
249	E	C	All mutations	C	2.985543683218102	>1
249	E	P	All mutations	P	2.0	>1
249	E	S	All mutations	S	2.0	>1
249	E	W	All mutations	W	2.86046511627907	>1
249	E	L	All mutations	L	2.0	>1
249	E	V	All mutations	V	1.0949088623507228	1
249	E	N	All mutations	N	1.9157762413576367	>1
249	E	G	All mutations	G	1.082338152105594	1
249	E	K	All mutations	K	0.9195474544311754	1
250	V	M	All mutations	M	1.1118793211816467	>1
250	V	G	All mutations	G	1.0	1
250	V	W	All mutations	W	2.1099937146448773	>1
250	V	I	All mutations	I	1.890634820867379	>1
250	V	R	All mutations	R	1.9987429289754872	>1
250	V	Y	All mutations	Y	2.9798868636077938	>1
250	V	F	All mutations	F	1.9817724701445631	>1
250	V	K	All mutations	K	2.0194846008799496	>1
250	V	T	All mutations	T	1.9981143934632306	>1
250	V	H	All mutations	H	2.9798868636077938	>1
250	V	V	All mutations	V	0.00251414204902577	1
250	V	S	All mutations	S	1.9981143934632306	>1
250	V	P	All mutations	P	1.9987429289754872	>1
250	V	E	All mutations	E	1.0207416719044626	1
250	V	D	All mutations	D	1.9805153991200504	>1
250	V	C	All mutations	C	2.9792583280955376	>1
250	V	A	All mutations	A	0.9993714644877436	1
250	V	Q	All mutations	Q	2.0201131363922062	>1
250	V	N	All mutations	N	2.9792583280955376	>1
250	V	L	All mutations	L	1.0018856065367694	1
251	R	C	All mutations	C	2.018227529855437	>1
251	R	V	All mutations	V	2.0	>1
251	R	H	All mutations	H	2.981772470144563	>1
251	R	K	All mutations	K	0.9817724701445631	1
251	R	R	All mutations	R	0.018227529855436832	1
251	R	L	All mutations	L	2.0	>1
251	R	Q	All mutations	Q	1.9817724701445631	>1
251	R	A	All mutations	A	2.0	>1
251	R	F	All mutations	F	3.0	>1
251	R	E	All mutations	E	1.9817724701445631	>1
251	R	M	All mutations	M	1.7548711502199874	>1
251	R	S	All mutations	S	1.0182275298554369	1
251	R	P	All mutations	P	2.0	>1
251	R	G	All mutations	G	1.0182275298554369	1
251	R	N	All mutations	N	1.9817724701445631	>1
251	R	W	All mutations	W	1.7730986800754243	>1
251	R	Y	All mutations	Y	2.981772470144563	>1
251	R	I	All mutations	I	1.2451288497800126	>1
251	R	T	All mutations	T	1.0	1
251	R	D	All mutations	D	2.981772470144563	>1
252	N	K	All mutations	K	1.0	1
252	N	A	All mutations	A	2.0	>1
252	N	C	All mutations	C	2.0	>1
252	N	T	All mutations	T	1.0	1
252	N	P	All mutations	P	2.0	>1
252	N	D	All mutations	D	1.0	1
252	N	M	All mutations	M	2.0	>1
252	N	W	All mutations	W	3.0	>1
252	N	L	All mutations	L	2.0	>1
252	N	Q	All mutations	Q	2.0	>1
252	N	V	All mutations	V	2.0	>1
252	N	S	All mutations	S	1.0	1
252	N	E	All mutations	E	2.0	>1
252	N	I	All mutations	I	1.0	1
252	N	N	All mutations	N	0.0	0
252	N	Y	All mutations	Y	1.0	1
252	N	H	All mutations	H	1.0	1
252	N	F	All mutations	F	2.0	>1
252	N	R	All mutations	R	2.0	>1
252	N	G	All mutations	G	2.0	>1
253	D	G	All mutations	G	1.0	1
253	D	F	All mutations	F	2.0	>1
253	D	A	All mutations	A	1.0	1
253	D	Q	All mutations	Q	2.0	>1
253	D	R	All mutations	R	2.0	>1
253	D	V	All mutations	V	1.0	1
253	D	S	All mutations	S	2.0	>1
253	D	M	All mutations	M	3.0	>1
253	D	T	All mutations	T	2.0	>1
253	D	Y	All mutations	Y	1.0	1
253	D	D	All mutations	D	0.0	0
253	D	C	All mutations	C	2.0	>1
253	D	W	All mutations	W	3.0	>1
253	D	P	All mutations	P	2.0	>1
253	D	I	All mutations	I	2.0	>1
253	D	K	All mutations	K	2.0	>1
253	D	N	All mutations	N	1.0	1
253	D	L	All mutations	L	2.0	>1
253	D	H	All mutations	H	1.0	1
253	D	E	All mutations	E	1.0	1
254	D	E	All mutations	E	1.0	1
254	D	S	All mutations	S	2.0	>1
254	D	A	All mutations	A	1.0	1
254	D	D	All mutations	D	0.0	0
254	D	F	All mutations	F	2.0	>1
254	D	M	All mutations	M	3.0	>1
254	D	G	All mutations	G	1.0	1
254	D	P	All mutations	P	2.0	>1
254	D	N	All mutations	N	1.0	1
254	D	H	All mutations	H	1.0	1
254	D	L	All mutations	L	2.0	>1
254	D	V	All mutations	V	1.0	1
254	D	Q	All mutations	Q	2.0	>1
254	D	Y	All mutations	Y	1.0	1
254	D	I	All mutations	I	2.0	>1
254	D	R	All mutations	R	2.0	>1
254	D	W	All mutations	W	3.0	>1
254	D	K	All mutations	K	2.0	>1
254	D	T	All mutations	T	2.0	>1
254	D	C	All mutations	C	2.0	>1
255	V	S	All mutations	S	1.9101194217473287	>1
255	V	K	All mutations	K	2.5285983658076683	>1
255	V	Y	All mutations	Y	2.3758642363293525	>1
255	V	H	All mutations	H	2.352608422375864	>1
255	V	N	All mutations	N	2.287869264613451	>1
255	V	F	All mutations	F	1.3758642363293525	>1
255	V	C	All mutations	C	2.3758642363293525	>1
255	V	T	All mutations	T	1.9082338152105593	>1
255	V	P	All mutations	P	1.972972972972973	>1
255	V	G	All mutations	G	1.1225644248900062	>1
255	V	R	All mutations	R	1.967316153362665	>1
255	V	W	All mutations	W	2.9798868636077938	>1
255	V	M	All mutations	M	1.8918918918918919	>1
255	V	A	All mutations	A	1.1225644248900062	>1
255	V	V	All mutations	V	0.12256442489000628	1
255	V	L	All mutations	L	0.9692017598994344	1
255	V	Q	All mutations	Q	2.5933375235700815	>1
255	V	I	All mutations	I	0.9245757385292269	1
255	V	E	All mutations	E	1.7429289754871151	>1
255	V	D	All mutations	D	1.5021998742928975	>1
256	D	D	All mutations	D	0.0006285355122564425	1
256	D	I	All mutations	I	1.9993714644877436	>1
256	D	C	All mutations	C	2.0	>1
256	D	R	All mutations	R	2.0	>1
256	D	Y	All mutations	Y	1.0	1
256	D	M	All mutations	M	2.9993714644877434	>1
256	D	N	All mutations	N	0.9993714644877436	1
256	D	H	All mutations	H	1.0	1
256	D	F	All mutations	F	2.0	>1
256	D	S	All mutations	S	1.9993714644877436	>1
256	D	T	All mutations	T	1.9993714644877436	>1
256	D	L	All mutations	L	2.0	>1
256	D	Q	All mutations	Q	2.0	>1
256	D	E	All mutations	E	1.0006285355122564	1
256	D	W	All mutations	W	3.0	>1
256	D	G	All mutations	G	1.0006285355122564	1
256	D	K	All mutations	K	1.9993714644877436	>1
256	D	V	All mutations	V	1.0006285355122564	1
256	D	A	All mutations	A	1.0006285355122564	1
256	D	P	All mutations	P	2.0	>1
257	Q	L	All mutations	L	1.0	1
257	Q	G	All mutations	G	1.9987429289754872	>1
257	Q	Y	All mutations	Y	2.001257071024513	>1
257	Q	S	All mutations	S	2.0	>1
257	Q	Q	All mutations	Q	0.001257071024512885	1
257	Q	I	All mutations	I	2.889377749842866	>1
257	Q	N	All mutations	N	2.001257071024513	>1
257	Q	H	All mutations	H	1.0012570710245128	1
257	Q	V	All mutations	V	2.0	>1
257	Q	C	All mutations	C	2.998742928975487	>1
257	Q	K	All mutations	K	1.0012570710245128	1
257	Q	D	All mutations	D	2.001257071024513	>1
257	Q	W	All mutations	W	2.109365179132621	>1
257	Q	T	All mutations	T	2.0	>1
257	Q	A	All mutations	A	2.0	>1
257	Q	P	All mutations	P	1.0	1
257	Q	E	All mutations	E	1.0012570710245128	1
257	Q	F	All mutations	F	3.0	>1
257	Q	R	All mutations	R	0.9987429289754871	1
257	Q	M	All mutations	M	2.110622250157134	>1
258	S	N	All mutations	N	1.0	1
258	S	E	All mutations	E	3.0	>1
258	S	A	All mutations	A	2.0	>1
258	S	F	All mutations	F	2.0	>1
258	S	W	All mutations	W	2.0	>1
258	S	Q	All mutations	Q	3.0	>1
258	S	L	All mutations	L	2.0	>1
258	S	D	All mutations	D	2.0	>1
258	S	P	All mutations	P	2.0	>1
258	S	K	All mutations	K	2.0	>1
258	S	V	All mutations	V	2.0	>1
258	S	G	All mutations	G	1.0	1
258	S	S	All mutations	S	0.0	0
258	S	C	All mutations	C	1.0	1
258	S	T	All mutations	T	1.0	1
258	S	M	All mutations	M	2.0	>1
258	S	H	All mutations	H	2.0	>1
258	S	Y	All mutations	Y	2.0	>1
258	S	R	All mutations	R	1.0	1
258	S	I	All mutations	I	1.0	1
259	L	G	All mutations	G	2.0	>1
259	L	M	All mutations	M	1.329352608422376	>1
259	L	D	All mutations	D	3.0	>1
259	L	H	All mutations	H	2.886235072281584	>1
259	L	S	All mutations	S	1.113764927718416	>1
259	L	Q	All mutations	Q	1.886235072281584	>1
259	L	C	All mutations	C	2.113764927718416	>1
259	L	E	All mutations	E	2.0	>1
259	L	A	All mutations	A	2.0	>1
259	L	W	All mutations	W	1.443117536140792	>1
259	L	K	All mutations	K	2.0	>1
259	L	F	All mutations	F	1.113764927718416	>1
259	L	R	All mutations	R	1.886235072281584	>1
259	L	P	All mutations	P	1.886235072281584	>1
259	L	T	All mutations	T	2.0	>1
259	L	N	All mutations	N	3.0	>1
259	L	I	All mutations	I	1.670647391577624	>1
259	L	L	All mutations	L	0.0	0
259	L	V	All mutations	V	1.0	1
259	L	Y	All mutations	Y	2.113764927718416	>1
260	I	H	All mutations	H	2.003142677561282	>1
260	I	C	All mutations	C	2.003142677561282	>1
260	I	E	All mutations	E	2.9918290383406663	>1
260	I	V	All mutations	V	0.9949717159019484	1
260	I	W	All mutations	W	3.0	>1
260	I	D	All mutations	D	1.9981143934632306	>1
260	I	M	All mutations	M	1.0050282840980516	1
260	I	Q	All mutations	Q	2.996857322438718	>1
260	I	T	All mutations	T	1.0050282840980516	1
260	I	Y	All mutations	Y	2.003142677561282	>1
260	I	S	All mutations	S	1.0081709616593337	1
260	I	F	All mutations	F	1.0031426775612822	1
260	I	I	All mutations	I	0.00502828409805154	1
260	I	K	All mutations	K	2.0018856065367694	>1
260	I	P	All mutations	P	2.0	>1
260	I	R	All mutations	R	1.9968573224387178	>1
260	I	L	All mutations	L	1.0	1
260	I	A	All mutations	A	1.9949717159019484	>1
260	I	N	All mutations	N	1.0081709616593337	1
260	I	G	All mutations	G	1.9949717159019484	>1
261	I	S	All mutations	S	1.0276555625392834	1
261	I	A	All mutations	A	1.9962287869264614	>1
261	I	I	All mutations	I	0.003771213073538655	1
261	I	T	All mutations	T	0.9974858579509742	1
261	I	E	All mutations	E	2.9723444374607166	>1
261	I	F	All mutations	F	1.0301697045883091	1
261	I	R	All mutations	R	1.972972972972973	>1
261	I	D	All mutations	D	2.0263984915147706	>1
261	I	G	All mutations	G	1.9993714644877436	>1
261	I	P	All mutations	P	1.9968573224387178	>1
261	I	M	All mutations	M	1.0037712130735386	1
261	I	C	All mutations	C	2.027027027027027	>1
261	I	Y	All mutations	Y	2.027027027027027	>1
261	I	H	All mutations	H	2.027027027027027	>1
261	I	V	All mutations	V	1.0025141420490258	1
261	I	N	All mutations	N	1.0276555625392834	1
261	I	Q	All mutations	Q	2.972972972972973	>1
261	I	K	All mutations	K	1.9736015084852294	>1
261	I	L	All mutations	L	1.0031426775612822	1
261	I	W	All mutations	W	3.0	>1
262	A	M	All mutations	M	2.9088623507228157	>1
262	A	W	All mutations	W	2.9088623507228157	>1
262	A	R	All mutations	R	2.0	>1
262	A	T	All mutations	T	1.0	1
262	A	C	All mutations	C	2.1005656819610308	>1
262	A	N	All mutations	N	2.1005656819610308	>1
262	A	K	All mutations	K	2.8994343180389692	>1
262	A	A	All mutations	A	0.0	0
262	A	H	All mutations	H	2.1005656819610308	>1
262	A	F	All mutations	F	2.1005656819610308	>1
262	A	E	All mutations	E	1.8994343180389692	>1
262	A	S	All mutations	S	1.0	1
262	A	Y	All mutations	Y	2.1005656819610308	>1
262	A	I	All mutations	I	2.0911376492771843	>1
262	A	G	All mutations	G	1.0	1
262	A	V	All mutations	V	1.0	1
262	A	P	All mutations	P	1.0	1
262	A	D	All mutations	D	1.1005656819610308	>1
262	A	Q	All mutations	Q	2.8994343180389692	>1
262	A	L	All mutations	L	2.0	>1
263	A	P	All mutations	P	1.0	1
263	A	S	All mutations	S	1.0	1
263	A	T	All mutations	T	1.0	1
263	A	N	All mutations	N	2.022627278441232	>1
263	A	H	All mutations	H	2.022627278441232	>1
263	A	G	All mutations	G	1.0	1
263	A	D	All mutations	D	1.022627278441232	1
263	A	L	All mutations	L	2.0	>1
263	A	E	All mutations	E	1.977372721558768	>1
263	A	I	All mutations	I	2.0062853551225643	>1
263	A	A	All mutations	A	0.0	0
263	A	W	All mutations	W	2.9937146448774357	>1
263	A	M	All mutations	M	2.9937146448774357	>1
263	A	K	All mutations	K	2.977372721558768	>1
263	A	R	All mutations	R	2.0	>1
263	A	Y	All mutations	Y	2.022627278441232	>1
263	A	V	All mutations	V	1.0	1
263	A	Q	All mutations	Q	2.977372721558768	>1
263	A	C	All mutations	C	2.022627278441232	>1
263	A	F	All mutations	F	2.022627278441232	>1
264	R	K	All mutations	K	1.0276555625392834	1
264	R	L	All mutations	L	1.9723444374607166	>1
264	R	C	All mutations	C	2.0	>1
264	R	V	All mutations	V	2.0	>1
264	R	A	All mutations	A	2.0	>1
264	R	E	All mutations	E	2.0	>1
264	R	P	All mutations	P	1.9723444374607166	>1
264	R	N	All mutations	N	2.0276555625392834	>1
264	R	S	All mutations	S	1.0276555625392834	1
264	R	Q	All mutations	Q	1.9723444374607166	>1
264	R	G	All mutations	G	1.0	1
264	R	R	All mutations	R	0.0	0
264	R	I	All mutations	I	1.487115021998743	>1
264	R	F	All mutations	F	3.0	>1
264	R	W	All mutations	W	1.5405405405405406	>1
264	R	M	All mutations	M	1.568196103079824	>1
264	R	T	All mutations	T	1.0276555625392834	1
264	R	D	All mutations	D	3.0	>1
264	R	Y	All mutations	Y	3.0	>1
264	R	H	All mutations	H	2.9723444374607166	>1
265	N	W	All mutations	W	2.9981143934632306	>1
265	N	L	All mutations	L	2.0	>1
265	N	K	All mutations	K	1.0018856065367694	1
265	N	N	All mutations	N	0.0018856065367693275	1
265	N	S	All mutations	S	0.9981143934632307	1
265	N	M	All mutations	M	2.0	>1
265	N	V	All mutations	V	2.0	>1
265	N	P	All mutations	P	2.0	>1
265	N	G	All mutations	G	1.9981143934632306	>1
265	N	R	All mutations	R	1.9981143934632306	>1
265	N	F	All mutations	F	2.0	>1
265	N	Y	All mutations	Y	1.0018856065367694	1
265	N	H	All mutations	H	1.0018856065367694	1
265	N	D	All mutations	D	1.0018856065367694	1
265	N	A	All mutations	A	2.0	>1
265	N	T	All mutations	T	1.0	1
265	N	E	All mutations	E	2.0018856065367694	>1
265	N	C	All mutations	C	1.9981143934632306	>1
265	N	Q	All mutations	Q	2.0018856065367694	>1
265	N	I	All mutations	I	1.0	1
266	I	A	All mutations	A	1.9993714644877436	>1
266	I	V	All mutations	V	0.9993714644877436	1
266	I	P	All mutations	P	2.0	>1
266	I	S	All mutations	S	1.473287240729101	>1
266	I	G	All mutations	G	1.9993714644877436	>1
266	I	W	All mutations	W	3.0	>1
266	I	R	All mutations	R	1.5273412947831553	>1
266	I	C	All mutations	C	2.473287240729101	>1
266	I	M	All mutations	M	1.0006285355122564	1
266	I	T	All mutations	T	1.0006285355122564	1
266	I	E	All mutations	E	2.5260842237586423	>1
266	I	L	All mutations	L	1.0	1
266	I	K	All mutations	K	1.5273412947831553	>1
266	I	I	All mutations	I	0.0006285355122564425	1
266	I	Q	All mutations	Q	2.526712759270899	>1
266	I	D	All mutations	D	2.472658705216845	>1
266	I	N	All mutations	N	1.4739157762413577	>1
266	I	H	All mutations	H	2.473287240729101	>1
266	I	Y	All mutations	Y	2.473287240729101	>1
266	I	F	All mutations	F	1.473287240729101	>1
267	V	L	All mutations	L	1.0	1
267	V	C	All mutations	C	2.543683218101823	>1
267	V	P	All mutations	P	2.0	>1
267	V	E	All mutations	E	1.4563167818981773	>1
267	V	T	All mutations	T	2.0	>1
267	V	H	All mutations	H	2.543683218101823	>1
267	V	A	All mutations	A	1.0	1
267	V	Y	All mutations	Y	2.543683218101823	>1
267	V	D	All mutations	D	1.5436832181018227	>1
267	V	M	All mutations	M	1.8799497171590196	>1
267	V	I	All mutations	I	1.1200502828409804	>1
267	V	V	All mutations	V	0.0	0
267	V	G	All mutations	G	1.0	1
267	V	K	All mutations	K	2.456316781898177	>1
267	V	Q	All mutations	Q	2.456316781898177	>1
267	V	S	All mutations	S	2.0	>1
267	V	N	All mutations	N	2.543683218101823	>1
267	V	W	All mutations	W	2.8799497171590196	>1
267	V	F	All mutations	F	1.5436832181018227	>1
267	V	R	All mutations	R	2.0	>1
268	R	F	All mutations	F	3.0	>1
268	R	H	All mutations	H	2.9993714644877434	>1
268	R	M	All mutations	M	1.6486486486486487	>1
268	R	E	All mutations	E	2.0	>1
268	R	S	All mutations	S	1.0006285355122564	1
268	R	N	All mutations	N	2.0006285355122566	>1
268	R	T	All mutations	T	1.0006285355122564	1
268	R	L	All mutations	L	1.9993714644877436	>1
268	R	C	All mutations	C	2.0	>1
268	R	P	All mutations	P	1.9993714644877436	>1
268	R	Q	All mutations	Q	1.9993714644877436	>1
268	R	A	All mutations	A	2.0	>1
268	R	K	All mutations	K	1.0006285355122564	1
268	R	R	All mutations	R	0.0	0
268	R	Y	All mutations	Y	3.0	>1
268	R	G	All mutations	G	1.0	1
268	R	V	All mutations	V	2.0	>1
268	R	W	All mutations	W	1.6480201131363923	>1
268	R	D	All mutations	D	3.0	>1
268	R	I	All mutations	I	1.3526084223758643	>1
269	R	H	All mutations	H	3.0	>1
269	R	M	All mutations	M	1.8686360779384035	>1
269	R	V	All mutations	V	2.0	>1
269	R	W	All mutations	W	1.8686360779384035	>1
269	R	G	All mutations	G	1.0	1
269	R	N	All mutations	N	2.0	>1
269	R	K	All mutations	K	1.0	1
269	R	T	All mutations	T	1.0	1
269	R	L	All mutations	L	2.0	>1
269	R	F	All mutations	F	3.0	>1
269	R	S	All mutations	S	1.0	1
269	R	E	All mutations	E	2.0	>1
269	R	R	All mutations	R	0.0	0
269	R	Y	All mutations	Y	3.0	>1
269	R	Q	All mutations	Q	2.0	>1
269	R	A	All mutations	A	2.0	>1
269	R	P	All mutations	P	2.0	>1
269	R	C	All mutations	C	2.0	>1
269	R	I	All mutations	I	1.1313639220615965	>1
269	R	D	All mutations	D	3.0	>1
270	A	R	All mutations	R	2.0	>1
270	A	Y	All mutations	Y	2.972972972972973	>1
270	A	C	All mutations	C	2.972972972972973	>1
270	A	I	All mutations	I	2.0018856065367694	>1
270	A	V	All mutations	V	1.0006285355122564	1
270	A	A	All mutations	A	0.0006285355122564425	1
270	A	Q	All mutations	Q	2.0263984915147706	>1
270	A	T	All mutations	T	1.0	1
270	A	H	All mutations	H	2.9736015084852294	>1
270	A	E	All mutations	E	1.027027027027027	1
270	A	K	All mutations	K	2.0263984915147706	>1
270	A	G	All mutations	G	1.0006285355122564	1
270	A	F	All mutations	F	2.972972972972973	>1
270	A	D	All mutations	D	1.9742300439974858	>1
270	A	M	All mutations	M	2.9981143934632306	>1
270	A	P	All mutations	P	1.0	1
270	A	N	All mutations	N	2.9736015084852294	>1
270	A	S	All mutations	S	0.9993714644877436	1
270	A	W	All mutations	W	2.9974858579509744	>1
270	A	L	All mutations	L	1.9993714644877436	>1
271	T	H	All mutations	H	2.996857322438718	>1
271	T	D	All mutations	D	2.9937146448774357	>1
271	T	A	All mutations	A	1.0031426775612822	1
271	T	V	All mutations	V	1.9905719673161533	>1
271	T	I	All mutations	I	1.1898177247014456	>1
271	T	Q	All mutations	Q	2.003142677561282	>1
271	T	P	All mutations	P	1.0062853551225643	1
271	T	T	All mutations	T	0.009428032683846637	1
271	T	L	All mutations	L	1.9937146448774357	>1
271	T	E	All mutations	E	2.0	>1
271	T	R	All mutations	R	1.0062853551225643	1
271	T	W	All mutations	W	2.807039597737272	>1
271	T	M	All mutations	M	1.80389692017599	>1
271	T	F	All mutations	F	2.9905719673161535	>1
271	T	G	All mutations	G	1.9968573224387178	>1
271	T	C	All mutations	C	2.996857322438718	>1
271	T	N	All mutations	N	2.0	>1
271	T	K	All mutations	K	1.0062853551225643	1
271	T	S	All mutations	S	1.0062853551225643	1
271	T	Y	All mutations	Y	2.996857322438718	>1
272	V	T	All mutations	T	2.0	>1
272	V	S	All mutations	S	2.0	>1
272	V	A	All mutations	A	1.0	1
272	V	Y	All mutations	Y	2.978629792583281	>1
272	V	D	All mutations	D	1.978629792583281	>1
272	V	C	All mutations	C	2.978629792583281	>1
272	V	Q	All mutations	Q	2.021370207416719	>1
272	V	I	All mutations	I	1.3406662476429918	>1
272	V	F	All mutations	F	1.978629792583281	>1
272	V	M	All mutations	M	1.6593337523570082	>1
272	V	E	All mutations	E	1.021370207416719	1
272	V	P	All mutations	P	2.0	>1
272	V	V	All mutations	V	0.0	0
272	V	K	All mutations	K	2.021370207416719	>1
272	V	G	All mutations	G	1.0	1
272	V	H	All mutations	H	2.978629792583281	>1
272	V	L	All mutations	L	1.0	1
272	V	W	All mutations	W	2.659333752357008	>1
272	V	R	All mutations	R	2.0	>1
272	V	N	All mutations	N	2.978629792583281	>1
273	S	F	All mutations	F	1.988686360779384	>1
273	S	P	All mutations	P	1.0	1
273	S	W	All mutations	W	1.9088623507228157	>1
273	S	A	All mutations	A	1.0	1
273	S	L	All mutations	L	1.011313639220616	1
273	S	D	All mutations	D	2.988686360779384	>1
273	S	C	All mutations	C	1.988686360779384	>1
273	S	I	All mutations	I	2.0911376492771843	>1
273	S	Y	All mutations	Y	1.988686360779384	>1
273	S	V	All mutations	V	2.0	>1
273	S	M	All mutations	M	2.9088623507228157	>1
273	S	S	All mutations	S	0.0	0
273	S	H	All mutations	H	2.988686360779384	>1
273	S	N	All mutations	N	2.988686360779384	>1
273	S	R	All mutations	R	2.0	>1
273	S	G	All mutations	G	2.0	>1
273	S	T	All mutations	T	1.0	1
273	S	E	All mutations	E	2.011313639220616	>1
273	S	Q	All mutations	Q	2.011313639220616	>1
273	S	K	All mutations	K	2.011313639220616	>1
274	A	N	All mutations	N	2.9912005028284097	>1
274	A	E	All mutations	E	1.0100565681961031	1
274	A	M	All mutations	M	2.839723444374607	>1
274	A	T	All mutations	T	0.9974858579509742	1
274	A	S	All mutations	S	0.9987429289754871	1
274	A	Y	All mutations	Y	2.992457573852923	>1
274	A	W	All mutations	W	2.84098051539912	>1
274	A	L	All mutations	L	1.9987429289754872	>1
274	A	Q	All mutations	Q	2.0062853551225643	>1
274	A	G	All mutations	G	1.0037712130735386	1
274	A	H	All mutations	H	2.9937146448774357	>1
274	A	R	All mutations	R	1.9974858579509742	>1
274	A	V	All mutations	V	1.0037712130735386	1
274	A	K	All mutations	K	2.003771213073539	>1
274	A	C	All mutations	C	2.992457573852923	>1
274	A	D	All mutations	D	1.9974858579509742	>1
274	A	A	All mutations	A	0.003771213073538655	1
274	A	F	All mutations	F	2.992457573852923	>1
274	A	I	All mutations	I	2.1552482715273413	>1
274	A	P	All mutations	P	1.0	1
275	D	Y	All mutations	Y	1.0	1
275	D	R	All mutations	R	2.0	>1
275	D	K	All mutations	K	2.0	>1
275	D	S	All mutations	S	2.0	>1
275	D	N	All mutations	N	1.0	1
275	D	W	All mutations	W	3.0	>1
275	D	G	All mutations	G	1.0	1
275	D	T	All mutations	T	2.0	>1
275	D	M	All mutations	M	3.0	>1
275	D	Q	All mutations	Q	2.0	>1
275	D	A	All mutations	A	1.0	1
275	D	D	All mutations	D	0.0	0
275	D	E	All mutations	E	1.0	1
275	D	I	All mutations	I	2.0	>1
275	D	C	All mutations	C	2.0	>1
275	D	L	All mutations	L	2.0	>1
275	D	P	All mutations	P	2.0	>1
275	D	F	All mutations	F	2.0	>1
275	D	V	All mutations	V	1.0	1
275	D	H	All mutations	H	1.0	1
276	P	T	All mutations	T	1.0	1
276	P	A	All mutations	A	1.0	1
276	P	F	All mutations	F	2.9918290383406663	>1
276	P	E	All mutations	E	2.0081709616593337	>1
276	P	V	All mutations	V	2.0	>1
276	P	Y	All mutations	Y	2.9918290383406663	>1
276	P	H	All mutations	H	1.9918290383406663	>1
276	P	D	All mutations	D	2.9918290383406663	>1
276	P	P	All mutations	P	0.0	0
276	P	G	All mutations	G	2.0	>1
276	P	L	All mutations	L	1.0	1
276	P	Q	All mutations	Q	1.0081709616593337	1
276	P	I	All mutations	I	2.269641734758014	>1
276	P	R	All mutations	R	1.0	1
276	P	S	All mutations	S	1.0	1
276	P	M	All mutations	M	2.730358265241986	>1
276	P	C	All mutations	C	2.9918290383406663	>1
276	P	N	All mutations	N	2.9918290383406663	>1
276	P	W	All mutations	W	2.730358265241986	>1
276	P	K	All mutations	K	2.0081709616593337	>1
277	L	W	All mutations	W	2.006913890634821	>1
277	L	L	All mutations	L	0.0	0
277	L	R	All mutations	R	1.4739157762413577	>1
277	L	Q	All mutations	Q	1.4789440603394093	>1
277	L	G	All mutations	G	2.0	>1
277	L	S	All mutations	S	1.5260842237586423	>1
277	L	D	All mutations	D	2.9949717159019484	>1
277	L	P	All mutations	P	1.4739157762413577	>1
277	L	N	All mutations	N	2.9949717159019484	>1
277	L	F	All mutations	F	1.5210559396605907	>1
277	L	C	All mutations	C	2.5210559396605907	>1
277	L	Y	All mutations	Y	2.5210559396605907	>1
277	L	T	All mutations	T	2.0	>1
277	L	K	All mutations	K	2.0050282840980516	>1
277	L	E	All mutations	E	2.0050282840980516	>1
277	L	H	All mutations	H	2.468887492143306	>1
277	L	V	All mutations	V	1.0	1
277	L	M	All mutations	M	1.4808296668761785	>1
277	L	A	All mutations	A	2.0	>1
277	L	I	All mutations	I	1.5191703331238215	>1
278	A	G	All mutations	G	1.0	1
278	A	Q	All mutations	Q	2.220615964802011	>1
278	A	V	All mutations	V	0.9993714644877436	1
278	A	L	All mutations	L	1.9993714644877436	>1
278	A	Y	All mutations	Y	2.779384035197989	>1
278	A	I	All mutations	I	2.0295411690760528	>1
278	A	F	All mutations	F	2.778755499685732	>1
278	A	C	All mutations	C	2.779384035197989	>1
278	A	M	All mutations	M	2.9692017598994345	>1
278	A	S	All mutations	S	1.0006285355122564	1
278	A	D	All mutations	D	1.7793840351979886	>1
278	A	R	All mutations	R	2.0	>1
278	A	H	All mutations	H	2.779384035197989	>1
278	A	W	All mutations	W	2.9698302954116906	>1
278	A	P	All mutations	P	1.0006285355122564	1
278	A	A	All mutations	A	0.0006285355122564425	1
278	A	E	All mutations	E	1.2206159648020114	>1
278	A	N	All mutations	N	2.779384035197989	>1
278	A	K	All mutations	K	2.220615964802011	>1
278	A	T	All mutations	T	1.0006285355122564	1
279	S	V	All mutations	V	1.9962287869264614	>1
279	S	H	All mutations	H	2.5417976115650536	>1
279	S	M	All mutations	M	2.7674418604651163	>1
279	S	I	All mutations	I	2.2325581395348837	>1
279	S	P	All mutations	P	1.0	1
279	S	Y	All mutations	Y	1.5455688246385921	>1
279	S	L	All mutations	L	1.4619736015084852	>1
279	S	W	All mutations	W	1.7712130735386549	>1
279	S	D	All mutations	D	2.538026398491515	>1
279	S	N	All mutations	N	2.5417976115650536	>1
279	S	Q	All mutations	Q	2.4582023884349464	>1
279	S	S	All mutations	S	0.003771213073538655	1
279	S	G	All mutations	G	1.9962287869264614	>1
279	S	K	All mutations	K	2.4582023884349464	>1
279	S	C	All mutations	C	1.5455688246385921	>1
279	S	E	All mutations	E	2.454431175361408	>1
279	S	T	All mutations	T	1.0	1
279	S	R	All mutations	R	2.0	>1
279	S	F	All mutations	F	1.5455688246385921	>1
279	S	A	All mutations	A	0.9962287869264613	1
280	L	P	All mutations	P	1.113764927718416	>1
280	L	K	All mutations	K	2.335009428032684	>1
280	L	V	All mutations	V	1.0	1
280	L	Y	All mutations	Y	2.5512256442489	>1
280	L	L	All mutations	L	0.0	0
280	L	F	All mutations	F	1.5512256442489	>1
280	L	T	All mutations	T	2.0	>1
280	L	M	All mutations	M	1.9277184160905092	>1
280	L	W	All mutations	W	2.813953488372093	>1
280	L	D	All mutations	D	2.664990571967316	>1
280	L	I	All mutations	I	1.0722815839094908	1
280	L	E	All mutations	E	2.335009428032684	>1
280	L	H	All mutations	H	1.7787554996857322	>1
280	L	N	All mutations	N	2.664990571967316	>1
280	L	G	All mutations	G	2.0	>1
280	L	C	All mutations	C	2.5512256442489	>1
280	L	R	All mutations	R	1.113764927718416	>1
280	L	Q	All mutations	Q	1.4487743557511	>1
280	L	A	All mutations	A	2.0	>1
280	L	S	All mutations	S	1.886235072281584	>1
281	L	K	All mutations	K	2.001257071024513	>1
281	L	F	All mutations	F	1.1231929604022628	>1
281	L	D	All mutations	D	2.9981143934632306	>1
281	L	N	All mutations	N	2.998742928975487	>1
281	L	C	All mutations	C	2.1231929604022626	>1
281	L	Q	All mutations	Q	1.8774355751099938	>1
281	L	T	All mutations	T	2.0	>1
281	L	W	All mutations	W	1.175989943431804	>1
281	L	Y	All mutations	Y	2.1231929604022626	>1
281	L	S	All mutations	S	1.1244500314267756	>1
281	L	A	All mutations	A	1.9993714644877436	>1
281	L	H	All mutations	H	2.874921433060968	>1
281	L	E	All mutations	E	2.0006285355122566	>1
281	L	M	All mutations	M	1.0515399120050284	1
281	L	L	All mutations	L	0.0006285355122564425	1
281	L	V	All mutations	V	0.9993714644877436	1
281	L	P	All mutations	P	1.8761785040854808	>1
281	L	I	All mutations	I	1.9484600879949716	>1
281	L	G	All mutations	G	1.9993714644877436	>1
281	L	R	All mutations	R	1.8761785040854808	>1
282	E	Q	All mutations	Q	1.0081709616593337	1
282	E	S	All mutations	S	1.9993714644877436	>1
282	E	D	All mutations	D	0.9930861093651792	1
282	E	G	All mutations	G	1.0	1
282	E	N	All mutations	N	1.993086109365179	>1
282	E	T	All mutations	T	1.9993714644877436	>1
282	E	Y	All mutations	Y	1.993086109365179	>1
282	E	C	All mutations	C	2.992457573852923	>1
282	E	P	All mutations	P	1.9993714644877436	>1
282	E	E	All mutations	E	0.008170961659333752	1
282	E	L	All mutations	L	2.0	>1
282	E	F	All mutations	F	2.992457573852923	>1
282	E	A	All mutations	A	0.9993714644877436	1
282	E	V	All mutations	V	1.0	1
282	E	I	All mutations	I	2.8654934003771215	>1
282	E	R	All mutations	R	2.0	>1
282	E	H	All mutations	H	1.993086109365179	>1
282	E	M	All mutations	M	2.1345065996228785	>1
282	E	K	All mutations	K	1.0081709616593337	1
282	E	W	All mutations	W	2.1345065996228785	>1
283	M	F	All mutations	F	2.0	>1
283	M	K	All mutations	K	1.0	1
283	M	A	All mutations	A	2.0	>1
283	M	C	All mutations	C	3.0	>1
283	M	G	All mutations	G	2.0	>1
283	M	E	All mutations	E	2.0	>1
283	M	H	All mutations	H	3.0	>1
283	M	Q	All mutations	Q	2.0	>1
283	M	W	All mutations	W	2.0	>1
283	M	V	All mutations	V	1.0	1
283	M	N	All mutations	N	2.0	>1
283	M	P	All mutations	P	2.0	>1
283	M	T	All mutations	T	1.0	1
283	M	M	All mutations	M	0.0	0
283	M	Y	All mutations	Y	3.0	>1
283	M	I	All mutations	I	1.0	1
283	M	L	All mutations	L	1.0	1
283	M	D	All mutations	D	3.0	>1
283	M	S	All mutations	S	2.0	>1
283	M	R	All mutations	R	1.0	1
284	C	M	All mutations	M	3.0	>1
284	C	D	All mutations	D	2.0	>1
284	C	A	All mutations	A	2.0	>1
284	C	G	All mutations	G	1.0	1
284	C	C	All mutations	C	0.0	0
284	C	Q	All mutations	Q	3.0	>1
284	C	P	All mutations	P	2.0	>1
284	C	R	All mutations	R	1.0	1
284	C	N	All mutations	N	2.0	>1
284	C	S	All mutations	S	1.0	1
284	C	E	All mutations	E	3.0	>1
284	C	W	All mutations	W	1.0	1
284	C	H	All mutations	H	2.0	>1
284	C	V	All mutations	V	2.0	>1
284	C	I	All mutations	I	2.0	>1
284	C	F	All mutations	F	1.0	1
284	C	T	All mutations	T	2.0	>1
284	C	Y	All mutations	Y	1.0	1
284	C	K	All mutations	K	3.0	>1
284	C	L	All mutations	L	2.0	>1
285	H	M	All mutations	M	3.0	>1
285	H	K	All mutations	K	2.0	>1
285	H	E	All mutations	E	2.0	>1
285	H	Q	All mutations	Q	1.0012570710245128	1
285	H	W	All mutations	W	2.998742928975487	>1
285	H	P	All mutations	P	1.0012570710245128	1
285	H	S	All mutations	S	1.9987429289754872	>1
285	H	H	All mutations	H	0.001257071024512885	1
285	H	F	All mutations	F	1.9987429289754872	>1
285	H	Y	All mutations	Y	0.9987429289754871	1
285	H	A	All mutations	A	2.0	>1
285	H	D	All mutations	D	1.0	1
285	H	N	All mutations	N	1.0	1
285	H	R	All mutations	R	1.0012570710245128	1
285	H	G	All mutations	G	2.0	>1
285	H	T	All mutations	T	2.0	>1
285	H	L	All mutations	L	1.0012570710245128	1
285	H	I	All mutations	I	2.0	>1
285	H	C	All mutations	C	1.9987429289754872	>1
285	H	V	All mutations	V	2.0	>1
286	S	R	All mutations	R	1.0	1
286	S	V	All mutations	V	1.9987429289754872	>1
286	S	N	All mutations	N	1.0012570710245128	1
286	S	P	All mutations	P	2.0	>1
286	S	H	All mutations	H	2.0	>1
286	S	L	All mutations	L	2.0	>1
286	S	W	All mutations	W	2.0	>1
286	S	I	All mutations	I	1.0012570710245128	1
286	S	F	All mutations	F	2.0	>1
286	S	C	All mutations	C	1.0	1
286	S	D	All mutations	D	1.9987429289754872	>1
286	S	E	All mutations	E	2.998742928975487	>1
286	S	Y	All mutations	Y	2.0	>1
286	S	M	All mutations	M	2.001257071024513	>1
286	S	T	All mutations	T	1.0012570710245128	1
286	S	G	All mutations	G	0.9987429289754871	1
286	S	K	All mutations	K	2.001257071024513	>1
286	S	A	All mutations	A	1.9987429289754872	>1
286	S	Q	All mutations	Q	3.0	>1
286	S	S	All mutations	S	0.001257071024512885	1
287	T	I	All mutations	I	1.0402262727844123	1
287	T	Q	All mutations	Q	2.0333123821495915	>1
287	T	Y	All mutations	Y	2.9666876178504085	>1
287	T	H	All mutations	H	2.9666876178504085	>1
287	T	A	All mutations	A	1.0	1
287	T	L	All mutations	L	2.0	>1
287	T	F	All mutations	F	2.9666876178504085	>1
287	T	V	All mutations	V	2.0	>1
287	T	E	All mutations	E	2.0333123821495915	>1
287	T	N	All mutations	N	1.9666876178504085	>1
287	T	R	All mutations	R	1.0333123821495915	1
287	T	P	All mutations	P	1.0	1
287	T	K	All mutations	K	1.0333123821495915	1
287	T	W	All mutations	W	2.9597737272155875	>1
287	T	C	All mutations	C	2.9666876178504085	>1
287	T	D	All mutations	D	2.9666876178504085	>1
287	T	S	All mutations	S	1.0	1
287	T	T	All mutations	T	0.0	0
287	T	M	All mutations	M	1.9597737272155877	>1
287	T	G	All mutations	G	2.0	>1
288	Q	K	All mutations	K	1.0150848522941547	1
288	Q	A	All mutations	A	2.0	>1
288	Q	L	All mutations	L	0.9855436832181018	1
288	Q	C	All mutations	C	2.9993714644877434	>1
288	Q	W	All mutations	W	2.7950974230043997	>1
288	Q	P	All mutations	P	1.0012570710245128	1
288	Q	V	All mutations	V	1.984286612193589	>1
288	Q	Y	All mutations	Y	2.0150848522941547	>1
288	Q	M	All mutations	M	2.7781269641734756	>1
288	Q	D	All mutations	D	2.0150848522941547	>1
288	Q	F	All mutations	F	2.9836580766813325	>1
288	Q	I	All mutations	I	2.1879321181646763	>1
288	Q	S	All mutations	S	2.0	>1
288	Q	Q	All mutations	Q	0.01759899434318039	1
288	Q	T	All mutations	T	1.9987429289754872	>1
288	Q	N	All mutations	N	2.013827781269642	>1
288	Q	G	All mutations	G	2.0	>1
288	Q	E	All mutations	E	1.0163419233186675	1
288	Q	H	All mutations	H	1.0163419233186675	1
288	Q	R	All mutations	R	1.0	1
289	I	D	All mutations	D	2.0201131363922062	>1
289	I	S	All mutations	S	1.022627278441232	1
289	I	P	All mutations	P	2.0	>1
289	I	W	All mutations	W	3.0	>1
289	I	R	All mutations	R	1.978629792583281	>1
289	I	E	All mutations	E	2.977372721558768	>1
289	I	F	All mutations	F	1.021370207416719	1
289	I	G	All mutations	G	1.9987429289754872	>1
289	I	T	All mutations	T	1.0012570710245128	1
289	I	C	All mutations	C	2.021370207416719	>1
289	I	V	All mutations	V	0.9987429289754871	1
289	I	I	All mutations	I	0.001257071024512885	1
289	I	M	All mutations	M	1.0012570710245128	1
289	I	Y	All mutations	Y	2.021370207416719	>1
289	I	L	All mutations	L	1.0	1
289	I	H	All mutations	H	2.021370207416719	>1
289	I	N	All mutations	N	1.022627278441232	1
289	I	Q	All mutations	Q	2.978629792583281	>1
289	I	A	All mutations	A	1.9987429289754872	>1
289	I	K	All mutations	K	1.9798868636077938	>1
290	G	R	All mutations	R	1.0	1
290	G	Y	All mutations	Y	2.5285983658076683	>1
290	G	M	All mutations	M	2.7064739157762414	>1
290	G	G	All mutations	G	0.0018856065367693275	1
290	G	A	All mutations	A	1.0018856065367694	1
290	G	N	All mutations	N	2.526712759270899	>1
290	G	W	All mutations	W	1.7083595223130106	>1
290	G	T	All mutations	T	1.9981143934632306	>1
290	G	L	All mutations	L	2.0	>1
290	G	E	All mutations	E	1.473287240729101	>1
290	G	H	All mutations	H	2.5285983658076683	>1
290	G	P	All mutations	P	2.0	>1
290	G	V	All mutations	V	1.0018856065367694	1
290	G	K	All mutations	K	2.4695160276555623	>1
290	G	S	All mutations	S	1.526712759270899	>1
290	G	D	All mutations	D	1.5304839723444374	>1
290	G	C	All mutations	C	1.528598365807668	>1
290	G	Q	All mutations	Q	2.4714016341923317	>1
290	G	I	All mutations	I	2.28975487115022	>1
290	G	F	All mutations	F	2.5285983658076683	>1
291	G	C	All mutations	C	1.9968573224387178	>1
291	G	L	All mutations	L	2.0	>1
291	G	H	All mutations	H	2.996857322438718	>1
291	G	G	All mutations	G	0.0	0
291	G	N	All mutations	N	2.996857322438718	>1
291	G	V	All mutations	V	1.0	1
291	G	I	All mutations	I	2.49465744814582	>1
291	G	T	All mutations	T	2.0	>1
291	G	Y	All mutations	Y	2.996857322438718	>1
291	G	E	All mutations	E	1.0031426775612822	1
291	G	M	All mutations	M	2.50534255185418	>1
291	G	K	All mutations	K	2.003142677561282	>1
291	G	A	All mutations	A	1.0	1
291	G	W	All mutations	W	1.5053425518541799	>1
291	G	R	All mutations	R	1.0	1
291	G	F	All mutations	F	2.996857322438718	>1
291	G	Q	All mutations	Q	2.003142677561282	>1
291	G	S	All mutations	S	1.9968573224387178	>1
291	G	D	All mutations	D	1.9968573224387178	>1
291	G	P	All mutations	P	2.0	>1
292	I	F	All mutations	F	1.957259585166562	>1
292	I	L	All mutations	L	1.1005656819610308	>1
292	I	I	All mutations	I	0.2941546197360151	1
292	I	Y	All mutations	Y	2.8529226901319924	>1
292	I	S	All mutations	S	1.8233815210559396	>1
292	I	H	All mutations	H	2.850408548082967	>1
292	I	V	All mutations	V	0.940289126335638	1
292	I	P	All mutations	P	1.8925204274041483	>1
292	I	R	All mutations	R	1.2363293526084225	>1
292	I	N	All mutations	N	2.021370207416719	>1
292	I	T	All mutations	T	1.0634820867379007	1
292	I	W	All mutations	W	2.977372721558768	>1
292	I	G	All mutations	G	1.8359522313010685	>1
292	I	E	All mutations	E	1.9824010056568195	>1
292	I	A	All mutations	A	1.731615336266499	>1
292	I	C	All mutations	C	2.8529226901319924	>1
292	I	K	All mutations	K	1.3142677561282212	>1
292	I	Q	All mutations	Q	2.143306096794469	>1
292	I	D	All mutations	D	2.6895034569453173	>1
292	I	M	All mutations	M	1.2501571338780642	>1
293	R	T	All mutations	T	1.0012570710245128	1
293	R	P	All mutations	P	1.9993714644877436	>1
293	R	Q	All mutations	Q	1.9949717159019484	>1
293	R	Y	All mutations	Y	2.994343180389692	>1
293	R	L	All mutations	L	1.9987429289754872	>1
293	R	R	All mutations	R	0.0069138906348208675	1
293	R	W	All mutations	W	1.175989943431804	>1
293	R	F	All mutations	F	2.998742928975487	>1
293	R	C	All mutations	C	2.0050282840980516	>1
293	R	A	All mutations	A	1.9993714644877436	>1
293	R	H	All mutations	H	2.9937146448774357	>1
293	R	I	All mutations	I	1.8302954116907606	>1
293	R	N	All mutations	N	1.9956002514142048	>1
293	R	K	All mutations	K	0.9968573224387178	1
293	R	G	All mutations	G	1.0050282840980516	1
293	R	M	All mutations	M	1.1709616593337524	>1
293	R	V	All mutations	V	1.9987429289754872	>1
293	R	D	All mutations	D	2.9937146448774357	>1
293	R	S	All mutations	S	1.0062853551225643	1
293	R	E	All mutations	E	1.9949717159019484	>1
294	M	M	All mutations	M	0.001257071024512885	1
294	M	R	All mutations	R	1.0006285355122564	1
294	M	I	All mutations	I	1.0	1
294	M	V	All mutations	V	1.0	1
294	M	D	All mutations	D	3.0	>1
294	M	G	All mutations	G	2.0	>1
294	M	Q	All mutations	Q	2.0	>1
294	M	P	All mutations	P	2.0	>1
294	M	E	All mutations	E	2.0	>1
294	M	S	All mutations	S	1.9993714644877436	>1
294	M	C	All mutations	C	2.9993714644877434	>1
294	M	T	All mutations	T	1.0006285355122564	1
294	M	W	All mutations	W	2.0	>1
294	M	A	All mutations	A	2.0	>1
294	M	K	All mutations	K	1.0006285355122564	1
294	M	H	All mutations	H	3.0	>1
294	M	L	All mutations	L	0.9993714644877436	1
294	M	Y	All mutations	Y	2.9993714644877434	>1
294	M	N	All mutations	N	2.0006285355122566	>1
294	M	F	All mutations	F	1.9993714644877436	>1
295	V	S	All mutations	S	1.9880578252671275	>1
295	V	A	All mutations	A	1.0301697045883091	1
295	V	H	All mutations	H	2.8573224387177873	>1
295	V	M	All mutations	M	1.6216216216216217	>1
295	V	L	All mutations	L	1.0119421747328725	1
295	V	E	All mutations	E	1.1829038340666247	>1
295	V	W	All mutations	W	2.6511627906976742	>1
295	V	N	All mutations	N	2.8158390949088625	>1
295	V	C	All mutations	C	2.857950974230044	>1
295	V	I	All mutations	I	1.3192960402262728	>1
295	V	Y	All mutations	Y	2.8573224387177873	>1
295	V	G	All mutations	G	1.0414833438089253	1
295	V	F	All mutations	F	1.8698931489629165	>1
295	V	K	All mutations	K	2.099937146448774	>1
295	V	T	All mutations	T	1.9472030169704588	>1
295	V	R	All mutations	R	1.9591451917033313	>1
295	V	Q	All mutations	Q	2.1414204902576994	>1
295	V	P	All mutations	P	1.988686360779384	>1
295	V	V	All mutations	V	0.05342551854179761	1
295	V	D	All mutations	D	1.8988057825267128	>1
296	D	D	All mutations	D	0.0018856065367693275	1
296	D	E	All mutations	E	1.0006285355122564	1
296	D	T	All mutations	T	1.9987429289754872	>1
296	D	K	All mutations	K	1.9981143934632306	>1
296	D	V	All mutations	V	1.0012570710245128	1
296	D	N	All mutations	N	0.9993714644877436	1
296	D	G	All mutations	G	1.0012570710245128	1
296	D	L	All mutations	L	2.0	>1
296	D	I	All mutations	I	1.9987429289754872	>1
296	D	R	All mutations	R	2.0	>1
296	D	Y	All mutations	Y	1.0006285355122564	1
296	D	P	All mutations	P	2.0	>1
296	D	W	All mutations	W	3.0	>1
296	D	A	All mutations	A	1.0012570710245128	1
296	D	F	All mutations	F	2.0006285355122566	>1
296	D	Q	All mutations	Q	1.9993714644877436	>1
296	D	H	All mutations	H	1.0006285355122564	1
296	D	S	All mutations	S	1.9987429289754872	>1
296	D	M	All mutations	M	2.998742928975487	>1
296	D	C	All mutations	C	2.0006285355122566	>1
297	I	C	All mutations	C	2.010056568196103	>1
297	I	D	All mutations	D	2.0081709616593337	>1
297	I	S	All mutations	S	1.0119421747328725	1
297	I	F	All mutations	F	1.0100565681961031	1
297	I	V	All mutations	V	0.9981143934632307	1
297	I	G	All mutations	G	1.9981143934632306	>1
297	I	I	All mutations	I	0.00251414204902577	1
297	I	K	All mutations	K	1.9924575738529227	>1
297	I	N	All mutations	N	1.012570710245129	1
297	I	Y	All mutations	Y	2.010056568196103	>1
297	I	W	All mutations	W	3.0	>1
297	I	T	All mutations	T	1.0025141420490258	1
297	I	M	All mutations	M	1.0025141420490258	1
297	I	E	All mutations	E	2.9880578252671275	>1
297	I	A	All mutations	A	1.9981143934632306	>1
297	I	P	All mutations	P	1.9993714644877436	>1
297	I	Q	All mutations	Q	2.9893148962916403	>1
297	I	H	All mutations	H	2.0094280326838465	>1
297	I	R	All mutations	R	1.9899434318038969	>1
297	I	L	All mutations	L	0.9993714644877436	1
298	L	C	All mutations	C	2.0	>1
298	L	Q	All mutations	Q	2.0050282840980516	>1
298	L	D	All mutations	D	2.0	>1
298	L	E	All mutations	E	3.0	>1
298	L	P	All mutations	P	1.0050282840980516	1
298	L	M	All mutations	M	1.9949717159019484	>1
298	L	W	All mutations	W	3.0	>1
298	L	R	All mutations	R	1.0050282840980516	1
298	L	S	All mutations	S	1.9949717159019484	>1
298	L	F	All mutations	F	1.0	1
298	L	Y	All mutations	Y	2.0	>1
298	L	A	All mutations	A	2.0	>1
298	L	N	All mutations	N	1.9949717159019484	>1
298	L	K	All mutations	K	2.9949717159019484	>1
298	L	G	All mutations	G	2.0	>1
298	L	T	All mutations	T	1.9949717159019484	>1
298	L	H	All mutations	H	1.0050282840980516	1
298	L	I	All mutations	I	0.9949717159019484	1
298	L	L	All mutations	L	0.00502828409805154	1
298	L	V	All mutations	V	1.0	1
299	R	S	All mutations	S	1.4896291640477688	>1
299	R	I	All mutations	I	2.1829038340666247	>1
299	R	P	All mutations	P	1.5474544311753613	>1
299	R	M	All mutations	M	1.7221873035826525	>1
299	R	W	All mutations	W	1.3086109365179133	>1
299	R	T	All mutations	T	1.4525455688246387	>1
299	R	L	All mutations	L	1.5474544311753613	>1
299	R	G	All mutations	G	1.0389692017598995	1
299	R	H	All mutations	H	2.508485229415462	>1
299	R	F	All mutations	F	3.0	>1
299	R	Y	All mutations	Y	2.9610307982401007	>1
299	R	V	All mutations	V	2.0	>1
299	R	E	All mutations	E	1.9610307982401005	>1
299	R	Q	All mutations	Q	1.508485229415462	>1
299	R	D	All mutations	D	2.9610307982401007	>1
299	R	K	All mutations	K	1.4135763670647392	>1
299	R	A	All mutations	A	2.0	>1
299	R	N	All mutations	N	2.413576367064739	>1
299	R	C	All mutations	C	2.0389692017598993	>1
299	R	R	All mutations	R	0.03896920175989944	1
300	Q	R	All mutations	R	0.9993714644877436	1
300	Q	Q	All mutations	Q	0.001257071024512885	1
300	Q	I	All mutations	I	2.1087366436203645	>1
300	Q	K	All mutations	K	1.0012570710245128	1
300	Q	W	All mutations	W	2.890634820867379	>1
300	Q	P	All mutations	P	1.0	1
300	Q	M	All mutations	M	2.8912633563796355	>1
300	Q	L	All mutations	L	1.0	1
300	Q	S	All mutations	S	2.0	>1
300	Q	D	All mutations	D	2.0	>1
300	Q	T	All mutations	T	2.0	>1
300	Q	N	All mutations	N	2.0	>1
300	Q	G	All mutations	G	1.9993714644877436	>1
300	Q	A	All mutations	A	2.0	>1
300	Q	F	All mutations	F	2.9993714644877434	>1
300	Q	C	All mutations	C	2.998742928975487	>1
300	Q	V	All mutations	V	2.0	>1
300	Q	Y	All mutations	Y	2.0	>1
300	Q	E	All mutations	E	1.0012570710245128	1
300	Q	H	All mutations	H	1.0	1
301	N	P	All mutations	P	2.0	>1
301	N	V	All mutations	V	2.0	>1
301	N	L	All mutations	L	2.0	>1
301	N	I	All mutations	I	1.0	1
301	N	W	All mutations	W	3.0	>1
301	N	M	All mutations	M	2.0	>1
301	N	S	All mutations	S	1.0	1
301	N	T	All mutations	T	1.0	1
301	N	F	All mutations	F	2.0	>1
301	N	Y	All mutations	Y	1.0	1
301	N	R	All mutations	R	2.0	>1
301	N	A	All mutations	A	2.0	>1
301	N	N	All mutations	N	0.0	0
301	N	K	All mutations	K	1.0	1
301	N	Q	All mutations	Q	2.0	>1
301	N	H	All mutations	H	1.0	1
301	N	D	All mutations	D	1.0	1
301	N	E	All mutations	E	2.0	>1
301	N	G	All mutations	G	2.0	>1
301	N	C	All mutations	C	2.0	>1
302	P	W	All mutations	W	2.9849151477058453	>1
302	P	M	All mutations	M	2.9849151477058453	>1
302	P	H	All mutations	H	1.951602765556254	>1
302	P	S	All mutations	S	1.0006285355122564	1
302	P	T	All mutations	T	1.0006285355122564	1
302	P	G	All mutations	G	2.0	>1
302	P	F	All mutations	F	2.9522313010685104	>1
302	P	P	All mutations	P	0.0006285355122564425	1
302	P	Y	All mutations	Y	2.951602765556254	>1
302	P	E	All mutations	E	2.047140163419233	>1
302	P	A	All mutations	A	1.0006285355122564	1
302	P	N	All mutations	N	2.951602765556254	>1
302	P	C	All mutations	C	2.9522313010685104	>1
302	P	V	All mutations	V	2.0	>1
302	P	R	All mutations	R	1.0	1
302	P	I	All mutations	I	2.0150848522941547	>1
302	P	L	All mutations	L	1.0	1
302	P	K	All mutations	K	2.047140163419233	>1
302	P	Q	All mutations	Q	1.0471401634192332	1
302	P	D	All mutations	D	2.951602765556254	>1
303	T	F	All mutations	F	2.8089252042740416	>1
303	T	I	All mutations	I	1.0421118793211817	1
303	T	R	All mutations	R	1.1873035826524199	>1
303	T	G	All mutations	G	2.0	>1
303	T	T	All mutations	T	0.003771213073538655	1
303	T	E	All mutations	E	2.1873035826524196	>1
303	T	Q	All mutations	Q	2.1873035826524196	>1
303	T	S	All mutations	S	1.0037712130735386	1
303	T	P	All mutations	P	1.0037712130735386	1
303	T	A	All mutations	A	1.0037712130735386	1
303	T	H	All mutations	H	2.8126964173475804	>1
303	T	Y	All mutations	Y	2.8126964173475804	>1
303	T	V	All mutations	V	1.9962287869264614	>1
303	T	N	All mutations	N	1.8126964173475801	>1
303	T	M	All mutations	M	1.950345694531741	>1
303	T	C	All mutations	C	2.8126964173475804	>1
303	T	K	All mutations	K	1.1873035826524199	>1
303	T	L	All mutations	L	1.9962287869264614	>1
303	T	D	All mutations	D	2.8126964173475804	>1
303	T	W	All mutations	W	2.95411690760528	>1
304	E	F	All mutations	F	2.9993714644877434	>1
304	E	I	All mutations	I	2.688874921433061	>1
304	E	G	All mutations	G	1.0	1
304	E	L	All mutations	L	2.0	>1
304	E	Q	All mutations	Q	1.0006285355122564	1
304	E	S	All mutations	S	2.0	>1
304	E	H	All mutations	H	1.9993714644877436	>1
304	E	M	All mutations	M	2.311125078566939	>1
304	E	W	All mutations	W	2.311125078566939	>1
304	E	T	All mutations	T	2.0	>1
304	E	P	All mutations	P	2.0	>1
304	E	D	All mutations	D	0.9993714644877436	1
304	E	V	All mutations	V	1.0	1
304	E	Y	All mutations	Y	1.9993714644877436	>1
304	E	K	All mutations	K	1.0006285355122564	1
304	E	C	All mutations	C	2.9993714644877434	>1
304	E	N	All mutations	N	1.9993714644877436	>1
304	E	E	All mutations	E	0.0006285355122564425	1
304	E	R	All mutations	R	2.0	>1
304	E	A	All mutations	A	1.0	1
305	E	D	All mutations	D	1.0	1
305	E	H	All mutations	H	2.0	>1
305	E	A	All mutations	A	1.0	1
305	E	C	All mutations	C	3.0	>1
305	E	Q	All mutations	Q	1.0	1
305	E	N	All mutations	N	2.0	>1
305	E	W	All mutations	W	2.7630421118793214	>1
305	E	I	All mutations	I	2.2369578881206786	>1
305	E	S	All mutations	S	2.0	>1
305	E	M	All mutations	M	2.7630421118793214	>1
305	E	V	All mutations	V	1.0	1
305	E	E	All mutations	E	0.0	0
305	E	T	All mutations	T	2.0	>1
305	E	P	All mutations	P	2.0	>1
305	E	R	All mutations	R	2.0	>1
305	E	L	All mutations	L	2.0	>1
305	E	K	All mutations	K	1.0	1
305	E	Y	All mutations	Y	2.0	>1
305	E	F	All mutations	F	3.0	>1
305	E	G	All mutations	G	1.0	1
306	Q	I	All mutations	I	2.1187932118164676	>1
306	Q	K	All mutations	K	1.0	1
306	Q	N	All mutations	N	2.0	>1
306	Q	L	All mutations	L	1.0	1
306	Q	F	All mutations	F	3.0	>1
306	Q	T	All mutations	T	2.0	>1
306	Q	A	All mutations	A	2.0	>1
306	Q	S	All mutations	S	2.0	>1
306	Q	Y	All mutations	Y	2.0	>1
306	Q	Q	All mutations	Q	0.0	0
306	Q	R	All mutations	R	1.0	1
306	Q	W	All mutations	W	2.8812067881835324	>1
306	Q	G	All mutations	G	2.0	>1
306	Q	M	All mutations	M	2.8812067881835324	>1
306	Q	V	All mutations	V	2.0	>1
306	Q	E	All mutations	E	1.0	1
306	Q	C	All mutations	C	3.0	>1
306	Q	P	All mutations	P	1.0	1
306	Q	D	All mutations	D	2.0	>1
306	Q	H	All mutations	H	1.0	1
307	A	C	All mutations	C	2.025769956002514	>1
307	A	F	All mutations	F	2.025769956002514	>1
307	A	K	All mutations	K	2.974230043997486	>1
307	A	E	All mutations	E	1.9742300439974858	>1
307	A	W	All mutations	W	2.996857322438718	>1
307	A	H	All mutations	H	2.025769956002514	>1
307	A	S	All mutations	S	1.0	1
307	A	Q	All mutations	Q	2.974230043997486	>1
307	A	N	All mutations	N	2.025769956002514	>1
307	A	A	All mutations	A	0.0	0
307	A	M	All mutations	M	2.996857322438718	>1
307	A	T	All mutations	T	1.0	1
307	A	Y	All mutations	Y	2.025769956002514	>1
307	A	R	All mutations	R	2.0	>1
307	A	L	All mutations	L	2.0	>1
307	A	G	All mutations	G	1.0	1
307	A	P	All mutations	P	1.0	1
307	A	D	All mutations	D	1.0257699560025142	1
307	A	I	All mutations	I	2.003142677561282	>1
307	A	V	All mutations	V	1.0	1
308	V	R	All mutations	R	2.0	>1
308	V	Q	All mutations	Q	2.0131992457573853	>1
308	V	S	All mutations	S	1.9993714644877436	>1
308	V	Y	All mutations	Y	2.9868007542426147	>1
308	V	T	All mutations	T	1.9993714644877436	>1
308	V	E	All mutations	E	1.0138277812696417	1
308	V	P	All mutations	P	2.0	>1
308	V	A	All mutations	A	1.0006285355122564	1
308	V	C	All mutations	C	2.9868007542426147	>1
308	V	F	All mutations	F	1.9868007542426147	>1
308	V	G	All mutations	G	1.0006285355122564	1
308	V	H	All mutations	H	2.9868007542426147	>1
308	V	L	All mutations	L	1.0	1
308	V	M	All mutations	M	1.0691389063482086	1
308	V	N	All mutations	N	2.986172218730358	>1
308	V	I	All mutations	I	1.9296040226272784	>1
308	V	W	All mutations	W	2.0697674418604652	>1
308	V	D	All mutations	D	1.987429289754871	>1
308	V	V	All mutations	V	0.0006285355122564425	1
308	V	K	All mutations	K	2.0125707102451287	>1
309	D	I	All mutations	I	1.9899434318038969	>1
309	D	L	All mutations	L	1.9993714644877436	>1
309	D	M	All mutations	M	2.989943431803897	>1
309	D	F	All mutations	F	2.0025141420490256	>1
309	D	Y	All mutations	Y	1.0081709616593337	1
309	D	V	All mutations	V	1.0087994971715901	1
309	D	G	All mutations	G	1.0050282840980516	1
309	D	K	All mutations	K	1.9924575738529227	>1
309	D	R	All mutations	R	1.9956002514142048	>1
309	D	A	All mutations	A	1.0094280326838467	1
309	D	T	All mutations	T	1.9905719673161533	>1
309	D	N	All mutations	N	0.9987429289754871	1
309	D	C	All mutations	C	1.9987429289754872	>1
309	D	D	All mutations	D	0.01759899434318039	1
309	D	S	All mutations	S	1.9861722187303583	>1
309	D	Q	All mutations	Q	2.0018856065367694	>1
309	D	H	All mutations	H	1.0081709616593337	1
309	D	W	All mutations	W	2.995600251414205	>1
309	D	E	All mutations	E	1.011313639220616	1
309	D	P	All mutations	P	2.0	>1
310	I	T	All mutations	T	1.0	1
310	I	G	All mutations	G	2.0	>1
310	I	H	All mutations	H	2.981772470144563	>1
310	I	W	All mutations	W	3.0	>1
310	I	V	All mutations	V	1.0	1
310	I	I	All mutations	I	0.0	0
310	I	A	All mutations	A	2.0	>1
310	I	R	All mutations	R	1.0182275298554369	1
310	I	D	All mutations	D	2.981772470144563	>1
310	I	E	All mutations	E	2.018227529855437	>1
310	I	S	All mutations	S	1.9817724701445631	>1
310	I	C	All mutations	C	2.981772470144563	>1
310	I	N	All mutations	N	1.9817724701445631	>1
310	I	Q	All mutations	Q	2.018227529855437	>1
310	I	P	All mutations	P	2.0	>1
310	I	F	All mutations	F	1.9817724701445631	>1
310	I	K	All mutations	K	1.0182275298554369	1
310	I	Y	All mutations	Y	2.981772470144563	>1
310	I	L	All mutations	L	1.0	1
310	I	M	All mutations	M	1.0	1
311	C	T	All mutations	T	2.0	>1
311	C	Y	All mutations	Y	1.0	1
311	C	S	All mutations	S	1.0	1
311	C	P	All mutations	P	2.0	>1
311	C	E	All mutations	E	3.0	>1
311	C	R	All mutations	R	1.0	1
311	C	V	All mutations	V	2.0	>1
311	C	D	All mutations	D	2.0	>1
311	C	L	All mutations	L	2.0	>1
311	C	K	All mutations	K	3.0	>1
311	C	H	All mutations	H	2.0	>1
311	C	Q	All mutations	Q	3.0	>1
311	C	G	All mutations	G	1.0	1
311	C	F	All mutations	F	1.0	1
311	C	N	All mutations	N	2.0	>1
311	C	M	All mutations	M	3.0	>1
311	C	W	All mutations	W	1.0	1
311	C	I	All mutations	I	2.0	>1
311	C	C	All mutations	C	0.0	0
311	C	A	All mutations	A	2.0	>1
312	K	C	All mutations	C	2.940289126335638	>1
312	K	L	All mutations	L	1.9993714644877436	>1
312	K	Y	All mutations	Y	2.059710873664362	>1
312	K	P	All mutations	P	1.9993714644877436	>1
312	K	Q	All mutations	Q	1.0590823381521055	1
312	K	I	All mutations	I	1.526712759270899	>1
312	K	K	All mutations	K	0.06033940917661848	1
312	K	N	All mutations	N	1.0603394091766185	1
312	K	F	All mutations	F	3.0	>1
312	K	M	All mutations	M	1.4745443117536141	>1
312	K	D	All mutations	D	2.059710873664362	>1
312	K	A	All mutations	A	2.0	>1
312	K	R	All mutations	R	0.940289126335638	1
312	K	W	All mutations	W	2.4142049025769956	>1
312	K	E	All mutations	E	1.0597108736643621	1
312	K	G	All mutations	G	1.9402891263356379	>1
312	K	S	All mutations	S	1.9409176618478945	>1
312	K	H	All mutations	H	2.0590823381521055	>1
312	K	V	All mutations	V	2.0	>1
312	K	T	All mutations	T	1.0006285355122564	1
313	A	T	All mutations	T	1.0	1
313	A	N	All mutations	N	2.9918290383406663	>1
313	A	R	All mutations	R	2.0	>1
313	A	A	All mutations	A	0.0	0
313	A	G	All mutations	G	1.0	1
313	A	H	All mutations	H	2.9918290383406663	>1
313	A	D	All mutations	D	1.9918290383406663	>1
313	A	K	All mutations	K	2.0081709616593337	>1
313	A	V	All mutations	V	1.0	1
313	A	E	All mutations	E	1.0081709616593337	1
313	A	S	All mutations	S	1.0	1
313	A	P	All mutations	P	1.0	1
313	A	F	All mutations	F	2.9918290383406663	>1
313	A	Y	All mutations	Y	2.9918290383406663	>1
313	A	C	All mutations	C	2.9918290383406663	>1
313	A	I	All mutations	I	2.004399748585795	>1
313	A	W	All mutations	W	2.995600251414205	>1
313	A	M	All mutations	M	2.995600251414205	>1
313	A	Q	All mutations	Q	2.0081709616593337	>1
313	A	L	All mutations	L	2.0	>1
314	A	H	All mutations	H	2.9912005028284097	>1
314	A	P	All mutations	P	1.0	1
314	A	T	All mutations	T	1.0	1
314	A	D	All mutations	D	1.9912005028284099	>1
314	A	K	All mutations	K	2.0087994971715903	>1
314	A	V	All mutations	V	1.0	1
314	A	C	All mutations	C	2.9912005028284097	>1
314	A	Q	All mutations	Q	2.0087994971715903	>1
314	A	W	All mutations	W	2.9824010056568198	>1
314	A	M	All mutations	M	2.9824010056568198	>1
314	A	S	All mutations	S	1.0	1
314	A	I	All mutations	I	2.0175989943431802	>1
314	A	Y	All mutations	Y	2.9912005028284097	>1
314	A	G	All mutations	G	1.0	1
314	A	F	All mutations	F	2.9912005028284097	>1
314	A	R	All mutations	R	2.0	>1
314	A	A	All mutations	A	0.0	0
314	A	L	All mutations	L	2.0	>1
314	A	E	All mutations	E	1.0087994971715901	1
314	A	N	All mutations	N	2.9912005028284097	>1
315	M	K	All mutations	K	1.0	1
315	M	C	All mutations	C	3.0	>1
315	M	G	All mutations	G	2.0	>1
315	M	Q	All mutations	Q	2.0	>1
315	M	H	All mutations	H	3.0	>1
315	M	N	All mutations	N	2.0	>1
315	M	W	All mutations	W	2.0087994971715903	>1
315	M	L	All mutations	L	1.0	1
315	M	M	All mutations	M	0.008799497171590195	1
315	M	I	All mutations	I	0.9912005028284098	1
315	M	F	All mutations	F	2.0	>1
315	M	Y	All mutations	Y	3.0	>1
315	M	R	All mutations	R	1.0	1
315	M	V	All mutations	V	1.0	1
315	M	S	All mutations	S	2.0	>1
315	M	D	All mutations	D	3.0	>1
315	M	T	All mutations	T	1.0	1
315	M	E	All mutations	E	2.0	>1
315	M	A	All mutations	A	2.0	>1
315	M	P	All mutations	P	2.0	>1
316	G	D	All mutations	D	1.0257699560025142	1
316	G	N	All mutations	N	2.025769956002514	>1
316	G	F	All mutations	F	2.025769956002514	>1
316	G	C	All mutations	C	1.0257699560025142	1
316	G	R	All mutations	R	1.0	1
316	G	W	All mutations	W	1.9924575738529227	>1
316	G	L	All mutations	L	2.0	>1
316	G	G	All mutations	G	0.0	0
316	G	A	All mutations	A	1.0	1
316	G	Q	All mutations	Q	2.974230043997486	>1
316	G	Y	All mutations	Y	2.025769956002514	>1
316	G	H	All mutations	H	2.025769956002514	>1
316	G	S	All mutations	S	1.0257699560025142	1
316	G	P	All mutations	P	2.0	>1
316	G	I	All mutations	I	2.007542426147077	>1
316	G	T	All mutations	T	2.0	>1
316	G	K	All mutations	K	2.974230043997486	>1
316	G	E	All mutations	E	1.9742300439974858	>1
316	G	V	All mutations	V	1.0	1
316	G	M	All mutations	M	2.992457573852923	>1
317	L	V	All mutations	V	1.0	1
317	L	R	All mutations	R	1.6323067253299812	>1
317	L	N	All mutations	N	2.986172218730358	>1
317	L	L	All mutations	L	0.00754242614707731	1
317	L	C	All mutations	C	2.360779384035198	>1
317	L	W	All mutations	W	1.6744186046511629	>1
317	L	S	All mutations	S	1.3676932746700188	>1
317	L	H	All mutations	H	2.6323067253299812	>1
317	L	I	All mutations	I	1.6863607793840352	>1
317	L	T	All mutations	T	1.993086109365179	>1
317	L	K	All mutations	K	2.0	>1
317	L	Q	All mutations	Q	1.646134506599623	>1
317	L	E	All mutations	E	2.006913890634821	>1
317	L	D	All mutations	D	2.993086109365179	>1
317	L	A	All mutations	A	2.0	>1
317	L	G	All mutations	G	2.0	>1
317	L	M	All mutations	M	1.2998114393463231	>1
317	L	P	All mutations	P	1.639220615964802	>1
317	L	Y	All mutations	Y	2.360779384035198	>1
317	L	F	All mutations	F	1.360779384035198	>1
318	R	R	All mutations	R	0.01948460087994972	1
318	R	T	All mutations	T	1.0006285355122564	1
318	R	E	All mutations	E	1.9817724701445631	>1
318	R	L	All mutations	L	1.9993714644877436	>1
318	R	C	All mutations	C	2.018227529855437	>1
318	R	M	All mutations	M	1.3123821495914518	>1
318	R	S	All mutations	S	1.0188560653676932	1
318	R	A	All mutations	A	2.0	>1
318	R	Y	All mutations	Y	2.9805153991200504	>1
318	R	V	All mutations	V	2.0	>1
318	R	K	All mutations	K	0.9824010056568196	1
318	R	H	All mutations	H	2.9798868636077938	>1
318	R	N	All mutations	N	1.9811439346323068	>1
318	R	G	All mutations	G	1.0188560653676932	1
318	R	D	All mutations	D	2.9805153991200504	>1
318	R	Q	All mutations	Q	1.9811439346323068	>1
318	R	W	All mutations	W	1.3306096794468887	>1
318	R	P	All mutations	P	1.9993714644877436	>1
318	R	I	All mutations	I	1.688874921433061	>1
318	R	F	All mutations	F	2.9993714644877434	>1
319	I	L	All mutations	L	1.0	1
319	I	H	All mutations	H	2.0087994971715903	>1
319	I	Q	All mutations	Q	2.9912005028284097	>1
319	I	K	All mutations	K	1.9918290383406663	>1
319	I	W	All mutations	W	3.0	>1
319	I	E	All mutations	E	2.9905719673161535	>1
319	I	Y	All mutations	Y	2.0087994971715903	>1
319	I	F	All mutations	F	1.0087994971715901	1
319	I	S	All mutations	S	1.0094280326838467	1
319	I	R	All mutations	R	1.9912005028284099	>1
319	I	C	All mutations	C	2.0087994971715903	>1
319	I	P	All mutations	P	2.0	>1
319	I	V	All mutations	V	0.9993714644877436	1
319	I	I	All mutations	I	0.0006285355122564425	1
319	I	N	All mutations	N	1.0094280326838467	1
319	I	A	All mutations	A	1.9993714644877436	>1
319	I	G	All mutations	G	1.9993714644877436	>1
319	I	D	All mutations	D	2.0081709616593337	>1
319	I	M	All mutations	M	1.0006285355122564	1
319	I	T	All mutations	T	1.0006285355122564	1
320	S	Y	All mutations	Y	2.0	>1
320	S	H	All mutations	H	2.0	>1
320	S	W	All mutations	W	2.0	>1
320	S	G	All mutations	G	1.0	1
320	S	S	All mutations	S	0.0	0
320	S	L	All mutations	L	2.0	>1
320	S	Q	All mutations	Q	3.0	>1
320	S	C	All mutations	C	1.0	1
320	S	P	All mutations	P	2.0	>1
320	S	A	All mutations	A	2.0	>1
320	S	V	All mutations	V	2.0	>1
320	S	D	All mutations	D	2.0	>1
320	S	T	All mutations	T	1.0	1
320	S	I	All mutations	I	1.0	1
320	S	E	All mutations	E	3.0	>1
320	S	M	All mutations	M	2.0	>1
320	S	R	All mutations	R	1.0	1
320	S	F	All mutations	F	2.0	>1
320	S	K	All mutations	K	2.0	>1
320	S	N	All mutations	N	1.0	1
321	S	Q	All mutations	Q	2.0697674418604652	>1
321	S	P	All mutations	P	1.0	1
321	S	W	All mutations	W	1.961659333752357	>1
321	S	G	All mutations	G	2.0	>1
321	S	E	All mutations	E	2.0697674418604652	>1
321	S	K	All mutations	K	2.0697674418604652	>1
321	S	I	All mutations	I	2.038340666247643	>1
321	S	Y	All mutations	Y	1.930232558139535	>1
321	S	F	All mutations	F	1.930232558139535	>1
321	S	D	All mutations	D	2.9302325581395348	>1
321	S	N	All mutations	N	2.9302325581395348	>1
321	S	R	All mutations	R	2.0	>1
321	S	M	All mutations	M	2.961659333752357	>1
321	S	A	All mutations	A	1.0	1
321	S	C	All mutations	C	1.930232558139535	>1
321	S	T	All mutations	T	1.0	1
321	S	S	All mutations	S	0.0	0
321	S	L	All mutations	L	1.069767441860465	1
321	S	H	All mutations	H	2.9302325581395348	>1
321	S	V	All mutations	V	2.0	>1
322	S	I	All mutations	I	2.0188560653676935	>1
322	S	V	All mutations	V	2.0	>1
322	S	L	All mutations	L	1.972972972972973	>1
322	S	G	All mutations	G	2.0	>1
322	S	Q	All mutations	Q	2.972972972972973	>1
322	S	N	All mutations	N	2.0263984915147706	>1
322	S	C	All mutations	C	1.027027027027027	1
322	S	M	All mutations	M	2.9811439346323065	>1
322	S	E	All mutations	E	2.9736015084852294	>1
322	S	F	All mutations	F	1.027027027027027	1
322	S	P	All mutations	P	0.9993714644877436	1
322	S	H	All mutations	H	2.025769956002514	>1
322	S	Y	All mutations	Y	1.027027027027027	1
322	S	K	All mutations	K	2.9736015084852294	>1
322	S	R	All mutations	R	1.9993714644877436	>1
322	S	S	All mutations	S	0.0006285355122564425	1
322	S	A	All mutations	A	1.0	1
322	S	D	All mutations	D	2.0263984915147706	>1
322	S	T	All mutations	T	1.0	1
322	S	W	All mutations	W	1.9817724701445631	>1
323	F	C	All mutations	C	1.0012570710245128	1
323	F	M	All mutations	M	2.0	>1
323	F	A	All mutations	A	2.0	>1
323	F	F	All mutations	F	0.001257071024512885	1
323	F	T	All mutations	T	2.0	>1
323	F	D	All mutations	D	2.0	>1
323	F	P	All mutations	P	1.9987429289754872	>1
323	F	K	All mutations	K	3.0	>1
323	F	V	All mutations	V	1.0	1
323	F	S	All mutations	S	1.0012570710245128	1
323	F	N	All mutations	N	2.0	>1
323	F	R	All mutations	R	1.9987429289754872	>1
323	F	E	All mutations	E	3.0	>1
323	F	I	All mutations	I	1.0	1
323	F	Q	All mutations	Q	2.998742928975487	>1
323	F	G	All mutations	G	2.0	>1
323	F	W	All mutations	W	2.001257071024513	>1
323	F	H	All mutations	H	1.9987429289754872	>1
323	F	Y	All mutations	Y	1.0012570710245128	1
323	F	L	All mutations	L	0.9987429289754871	1
324	S	D	All mutations	D	2.0	>1
324	S	I	All mutations	I	1.0	1
324	S	Q	All mutations	Q	3.0	>1
324	S	V	All mutations	V	2.0	>1
324	S	P	All mutations	P	2.0	>1
324	S	N	All mutations	N	1.0	1
324	S	H	All mutations	H	2.0	>1
324	S	G	All mutations	G	1.0	1
324	S	R	All mutations	R	1.0	1
324	S	Y	All mutations	Y	2.0	>1
324	S	E	All mutations	E	3.0	>1
324	S	W	All mutations	W	2.0	>1
324	S	L	All mutations	L	2.0	>1
324	S	T	All mutations	T	1.0	1
324	S	S	All mutations	S	0.0	0
324	S	M	All mutations	M	2.0	>1
324	S	C	All mutations	C	1.0	1
324	S	A	All mutations	A	2.0	>1
324	S	K	All mutations	K	2.0	>1
324	S	F	All mutations	F	2.0	>1
325	F	D	All mutations	D	2.0	>1
325	F	A	All mutations	A	2.0	>1
325	F	Y	All mutations	Y	1.0	1
325	F	P	All mutations	P	2.0	>1
325	F	I	All mutations	I	1.0	1
325	F	W	All mutations	W	2.0	>1
325	F	H	All mutations	H	2.0	>1
325	F	N	All mutations	N	2.0	>1
325	F	C	All mutations	C	1.0	1
325	F	E	All mutations	E	3.0	>1
325	F	Q	All mutations	Q	3.0	>1
325	F	G	All mutations	G	2.0	>1
325	F	M	All mutations	M	2.0	>1
325	F	L	All mutations	L	1.0	1
325	F	F	All mutations	F	0.0	0
325	F	V	All mutations	V	1.0	1
325	F	R	All mutations	R	2.0	>1
325	F	K	All mutations	K	3.0	>1
325	F	S	All mutations	S	1.0	1
325	F	T	All mutations	T	2.0	>1
326	G	R	All mutations	R	1.0	1
326	G	M	All mutations	M	2.9805153991200504	>1
326	G	H	All mutations	H	2.546825895663105	>1
326	G	D	All mutations	D	1.546825895663105	>1
326	G	T	All mutations	T	2.0	>1
326	G	K	All mutations	K	2.453174104336895	>1
326	G	L	All mutations	L	2.0	>1
326	G	S	All mutations	S	1.546825895663105	>1
326	G	G	All mutations	G	0.0	0
326	G	F	All mutations	F	2.546825895663105	>1
326	G	C	All mutations	C	1.546825895663105	>1
326	G	W	All mutations	W	1.9805153991200504	>1
326	G	Y	All mutations	Y	2.546825895663105	>1
326	G	Q	All mutations	Q	2.453174104336895	>1
326	G	V	All mutations	V	1.0	1
326	G	I	All mutations	I	2.0194846008799496	>1
326	G	P	All mutations	P	2.0	>1
326	G	N	All mutations	N	2.546825895663105	>1
326	G	A	All mutations	A	1.0	1
326	G	E	All mutations	E	1.453174104336895	>1
327	G	E	All mutations	E	1.4236329352608423	>1
327	G	W	All mutations	W	1.944688874921433	>1
327	G	A	All mutations	A	1.0	1
327	G	H	All mutations	H	2.5751099937146447	>1
327	G	K	All mutations	K	2.423632935260842	>1
327	G	S	All mutations	S	1.5757385292269013	>1
327	G	Y	All mutations	Y	2.5751099937146447	>1
327	G	T	All mutations	T	2.0	>1
327	G	M	All mutations	M	2.9440603394091767	>1
327	G	L	All mutations	L	2.0	>1
327	G	C	All mutations	C	1.5763670647391577	>1
327	G	F	All mutations	F	2.5757385292269013	>1
327	G	R	All mutations	R	1.0006285355122564	1
327	G	N	All mutations	N	2.5751099937146447	>1
327	G	P	All mutations	P	2.0	>1
327	G	I	All mutations	I	2.0559396605908233	>1
327	G	G	All mutations	G	0.0006285355122564425	1
327	G	D	All mutations	D	1.5751099937146449	>1
327	G	Q	All mutations	Q	2.423632935260842	>1
327	G	V	All mutations	V	1.0	1
328	F	R	All mutations	R	1.9974858579509742	>1
328	F	F	All mutations	F	0.0031426775612822125	1
328	F	M	All mutations	M	2.0006285355122566	>1
328	F	H	All mutations	H	1.9968573224387178	>1
328	F	P	All mutations	P	1.9974858579509742	>1
328	F	I	All mutations	I	1.0006285355122564	1
328	F	C	All mutations	C	1.0025141420490258	1
328	F	W	All mutations	W	2.0025141420490256	>1
328	F	T	All mutations	T	2.0	>1
328	F	E	All mutations	E	2.9993714644877434	>1
328	F	K	All mutations	K	2.9993714644877434	>1
328	F	D	All mutations	D	1.9993714644877436	>1
328	F	V	All mutations	V	1.0006285355122564	1
328	F	G	All mutations	G	2.0	>1
328	F	Q	All mutations	Q	2.996857322438718	>1
328	F	L	All mutations	L	0.9981143934632307	1
328	F	N	All mutations	N	1.9993714644877436	>1
328	F	S	All mutations	S	1.0025141420490258	1
328	F	A	All mutations	A	2.0	>1
328	F	Y	All mutations	Y	1.0018856065367694	1
329	T	V	All mutations	V	1.9987429289754872	>1
329	T	N	All mutations	N	1.0012570710245128	1
329	T	D	All mutations	D	2.001257071024513	>1
329	T	T	All mutations	T	0.001257071024512885	1
329	T	H	All mutations	H	2.001257071024513	>1
329	T	P	All mutations	P	1.0012570710245128	1
329	T	E	All mutations	E	2.998742928975487	>1
329	T	G	All mutations	G	2.0	>1
329	T	Q	All mutations	Q	2.998742928975487	>1
329	T	R	All mutations	R	1.9987429289754872	>1
329	T	S	All mutations	S	1.0	1
329	T	F	All mutations	F	2.0	>1
329	T	I	All mutations	I	0.9993714644877436	1
329	T	L	All mutations	L	1.9987429289754872	>1
329	T	Y	All mutations	Y	2.001257071024513	>1
329	T	C	All mutations	C	2.001257071024513	>1
329	T	K	All mutations	K	1.9987429289754872	>1
329	T	A	All mutations	A	1.0012570710245128	1
329	T	M	All mutations	M	1.9981143934632306	>1
329	T	W	All mutations	W	2.9993714644877434	>1
330	F	V	All mutations	V	1.0006285355122564	1
330	F	H	All mutations	H	1.9993714644877436	>1
330	F	T	All mutations	T	2.0	>1
330	F	F	All mutations	F	0.0006285355122564425	1
330	F	K	All mutations	K	2.9993714644877434	>1
330	F	A	All mutations	A	2.0	>1
330	F	L	All mutations	L	1.0006285355122564	1
330	F	E	All mutations	E	2.9993714644877434	>1
330	F	D	All mutations	D	1.9993714644877436	>1
330	F	S	All mutations	S	1.0	1
330	F	G	All mutations	G	2.0	>1
330	F	P	All mutations	P	2.0	>1
330	F	M	All mutations	M	2.0006285355122566	>1
330	F	C	All mutations	C	1.0	1
330	F	N	All mutations	N	1.9993714644877436	>1
330	F	Q	All mutations	Q	2.9993714644877434	>1
330	F	R	All mutations	R	2.0	>1
330	F	Y	All mutations	Y	0.9993714644877436	1
330	F	W	All mutations	W	2.0	>1
330	F	I	All mutations	I	1.0006285355122564	1
331	K	P	All mutations	P	2.0	>1
331	K	S	All mutations	S	2.0	>1
331	K	R	All mutations	R	1.0	1
331	K	A	All mutations	A	2.0	>1
331	K	W	All mutations	W	2.976115650534255	>1
331	K	Q	All mutations	Q	1.0	1
331	K	E	All mutations	E	1.0	1
331	K	L	All mutations	L	2.0	>1
331	K	G	All mutations	G	2.0	>1
331	K	F	All mutations	F	3.0	>1
331	K	Y	All mutations	Y	2.0	>1
331	K	T	All mutations	T	1.0	1
331	K	N	All mutations	N	1.0	1
331	K	K	All mutations	K	0.0	0
331	K	M	All mutations	M	1.9761156505342552	>1
331	K	C	All mutations	C	3.0	>1
331	K	V	All mutations	V	2.0	>1
331	K	D	All mutations	D	2.0	>1
331	K	H	All mutations	H	2.0	>1
331	K	I	All mutations	I	1.0238843494657448	1
332	R	Q	All mutations	Q	1.9937146448774357	>1
332	R	E	All mutations	E	2.0	>1
332	R	C	All mutations	C	2.0	>1
332	R	K	All mutations	K	1.0062853551225643	1
332	R	W	All mutations	W	1.737272155876807	>1
332	R	Y	All mutations	Y	3.0	>1
332	R	S	All mutations	S	1.0062853551225643	1
332	R	L	All mutations	L	1.9937146448774357	>1
332	R	V	All mutations	V	2.0	>1
332	R	F	All mutations	F	3.0	>1
332	R	I	All mutations	I	1.2690131992457574	>1
332	R	R	All mutations	R	0.0	0
332	R	A	All mutations	A	2.0	>1
332	R	M	All mutations	M	1.7435575109993715	>1
332	R	G	All mutations	G	1.0	1
332	R	P	All mutations	P	1.9937146448774357	>1
332	R	D	All mutations	D	3.0	>1
332	R	T	All mutations	T	1.0062853551225643	1
332	R	N	All mutations	N	2.0062853551225643	>1
332	R	H	All mutations	H	2.9937146448774357	>1
333	T	N	All mutations	N	2.0	>1
333	T	A	All mutations	A	1.0018856065367694	1
333	T	F	All mutations	F	2.9981143934632306	>1
333	T	V	All mutations	V	1.9981143934632306	>1
333	T	P	All mutations	P	1.0018856065367694	1
333	T	I	All mutations	I	1.021370207416719	1
333	T	T	All mutations	T	0.0018856065367693275	1
333	T	Y	All mutations	Y	3.0	>1
333	T	S	All mutations	S	1.0018856065367694	1
333	T	R	All mutations	R	1.0	1
333	T	L	All mutations	L	1.9981143934632306	>1
333	T	C	All mutations	C	3.0	>1
333	T	D	All mutations	D	3.0	>1
333	T	W	All mutations	W	2.9767441860465116	>1
333	T	E	All mutations	E	2.0	>1
333	T	K	All mutations	K	1.0	1
333	T	G	All mutations	G	2.0	>1
333	T	M	All mutations	M	1.9748585795097422	>1
333	T	H	All mutations	H	3.0	>1
333	T	Q	All mutations	Q	2.0	>1
334	S	C	All mutations	C	1.0012570710245128	1
334	S	S	All mutations	S	0.00251414204902577	1
334	S	D	All mutations	D	1.9987429289754872	>1
334	S	E	All mutations	E	2.9974858579509744	>1
334	S	T	All mutations	T	1.0012570710245128	1
334	S	V	All mutations	V	1.9987429289754872	>1
334	S	W	All mutations	W	2.0	>1
334	S	A	All mutations	A	1.9987429289754872	>1
334	S	L	All mutations	L	2.0	>1
334	S	H	All mutations	H	2.0	>1
334	S	K	All mutations	K	2.0	>1
334	S	M	All mutations	M	2.0006285355122566	>1
334	S	F	All mutations	F	2.0006285355122566	>1
334	S	R	All mutations	R	1.0	1
334	S	Y	All mutations	Y	2.0	>1
334	S	G	All mutations	G	0.9993714644877436	1
334	S	P	All mutations	P	2.0	>1
334	S	Q	All mutations	Q	2.998742928975487	>1
334	S	I	All mutations	I	1.0018856065367694	1
334	S	N	All mutations	N	1.0012570710245128	1
335	G	T	All mutations	T	2.0	>1
335	G	H	All mutations	H	2.8233815210559396	>1
335	G	A	All mutations	A	1.0	1
335	G	F	All mutations	F	2.8233815210559396	>1
335	G	I	All mutations	I	2.419233186675047	>1
335	G	V	All mutations	V	1.0	1
335	G	W	All mutations	W	1.5807668133249528	>1
335	G	C	All mutations	C	1.8233815210559396	>1
335	G	M	All mutations	M	2.580766813324953	>1
335	G	K	All mutations	K	2.1766184789440604	>1
335	G	L	All mutations	L	2.0	>1
335	G	N	All mutations	N	2.8233815210559396	>1
335	G	P	All mutations	P	2.0	>1
335	G	D	All mutations	D	1.8233815210559396	>1
335	G	G	All mutations	G	0.0	0
335	G	Y	All mutations	Y	2.8233815210559396	>1
335	G	E	All mutations	E	1.1766184789440604	>1
335	G	S	All mutations	S	1.8233815210559396	>1
335	G	Q	All mutations	Q	2.1766184789440604	>1
335	G	R	All mutations	R	1.0	1
336	S	S	All mutations	S	0.0018856065367693275	1
336	S	V	All mutations	V	1.9981143934632306	>1
336	S	M	All mutations	M	2.6203645505971087	>1
336	S	P	All mutations	P	1.0006285355122564	1
336	S	I	All mutations	I	2.3783783783783785	>1
336	S	E	All mutations	E	2.085480829666876	>1
336	S	N	All mutations	N	2.913262099308611	>1
336	S	W	All mutations	W	1.622250157133878	>1
336	S	Q	All mutations	Q	2.086737900691389	>1
336	S	R	All mutations	R	2.0	>1
336	S	H	All mutations	H	2.913262099308611	>1
336	S	G	All mutations	G	1.9987429289754872	>1
336	S	D	All mutations	D	2.912005028284098	>1
336	S	K	All mutations	K	2.086737900691389	>1
336	S	Y	All mutations	Y	1.914519170333124	>1
336	S	L	All mutations	L	1.0873664362036455	1
336	S	T	All mutations	T	1.0006285355122564	1
336	S	F	All mutations	F	1.9138906348208673	>1
336	S	A	All mutations	A	0.9993714644877436	1
336	S	C	All mutations	C	1.914519170333124	>1
337	S	R	All mutations	R	1.9993714644877436	>1
337	S	K	All mutations	K	2.539912005028284	>1
337	S	L	All mutations	L	1.541169076052797	>1
337	S	F	All mutations	F	1.4600879949717158	>1
337	S	M	All mutations	M	2.9836580766813325	>1
337	S	P	All mutations	P	1.0	1
337	S	S	All mutations	S	0.0006285355122564425	1
337	S	W	All mutations	W	1.9849151477058453	>1
337	S	V	All mutations	V	2.0	>1
337	S	E	All mutations	E	2.5405405405405403	>1
337	S	Q	All mutations	Q	2.5405405405405403	>1
337	S	N	All mutations	N	2.458830923947203	>1
337	S	A	All mutations	A	1.0	1
337	S	H	All mutations	H	2.4594594594594597	>1
337	S	D	All mutations	D	2.4594594594594597	>1
337	S	G	All mutations	G	2.0	>1
337	S	T	All mutations	T	0.9993714644877436	1
337	S	Y	All mutations	Y	1.4600879949717158	>1
337	S	C	All mutations	C	1.4600879949717158	>1
337	S	I	All mutations	I	2.0150848522941547	>1
338	V	W	All mutations	W	2.994343180389692	>1
338	V	A	All mutations	A	1.1238214959145192	>1
338	V	F	All mutations	F	1.0672532998114392	1
338	V	R	All mutations	R	1.9949717159019484	>1
338	V	H	All mutations	H	2.0559396605908233	>1
338	V	P	All mutations	P	1.988686360779384	>1
338	V	C	All mutations	C	2.0559396605908233	>1
338	V	G	All mutations	G	1.135135135135135	>1
338	V	Q	All mutations	Q	2.9440603394091767	>1
338	V	M	All mutations	M	1.8705216844751729	>1
338	V	N	All mutations	N	1.9208045254556882	>1
338	V	K	All mutations	K	2.8089252042740416	>1
338	V	Y	All mutations	Y	2.0559396605908233	>1
338	V	E	All mutations	E	2.0791954745443118	>1
338	V	T	All mutations	T	1.8535512256442488	>1
338	V	L	All mutations	L	1.011313639220616	1
338	V	D	All mutations	D	1.1910747957259584	>1
338	V	V	All mutations	V	0.1464487743557511	1
338	V	S	All mutations	S	1.8686360779384035	>1
338	V	I	All mutations	I	0.8818353236957888	1
339	K	L	All mutations	L	1.9993714644877436	>1
339	K	M	All mutations	M	1.782526712759271	>1
339	K	V	All mutations	V	1.9962287869264614	>1
339	K	Q	All mutations	Q	1.175989943431804	>1
339	K	R	All mutations	R	0.9201759899434317	1
339	K	S	All mutations	S	1.8246385920804526	>1
339	K	T	All mutations	T	0.9321181646763043	1
339	K	W	All mutations	W	2.686360779384035	>1
339	K	N	All mutations	N	1.157762413576367	>1
339	K	P	All mutations	P	1.928975487115022	>1
339	K	Y	All mutations	Y	2.1546197360150847	>1
339	K	A	All mutations	A	1.9258328095537398	>1
339	K	I	All mutations	I	1.2225015713387806	>1
339	K	H	All mutations	H	2.1546197360150847	>1
339	K	F	All mutations	F	2.988686360779384	>1
339	K	E	All mutations	E	1.1728472658705218	>1
339	K	K	All mutations	K	0.1791326209930861	1
339	K	G	All mutations	G	1.9032055311125078	>1
339	K	D	All mutations	D	2.1514770584538025	>1
339	K	C	All mutations	C	2.8956631049654304	>1
340	R	M	All mutations	M	1.4651162790697674	>1
340	R	L	All mutations	L	1.9987429289754872	>1
340	R	V	All mutations	V	1.9962287869264614	>1
340	R	D	All mutations	D	2.6492771841609053	>1
340	R	Y	All mutations	Y	2.651791326209931	>1
340	R	N	All mutations	N	1.6543054682589566	>1
340	R	P	All mutations	P	2.0	>1
340	R	E	All mutations	E	1.6530483972344439	>1
340	R	H	All mutations	H	2.651791326209931	>1
340	R	T	All mutations	T	1.0025141420490258	1
340	R	I	All mutations	I	1.5373978629792584	>1
340	R	R	All mutations	R	0.3519798868636078	1
340	R	F	All mutations	F	2.996857322438718	>1
340	R	Q	All mutations	Q	1.6555625392834694	>1
340	R	S	All mutations	S	1.3482086737900691	>1
340	R	K	All mutations	K	0.6580766813324953	1
340	R	G	All mutations	G	1.345065996228787	>1
340	R	W	All mutations	W	1.8114393463230674	>1
340	R	C	All mutations	C	2.3456945317410436	>1
340	R	A	All mutations	A	1.9974858579509742	>1
341	E	C	All mutations	C	2.9974858579509744	>1
341	E	M	All mutations	M	2.8302954116907606	>1
341	E	E	All mutations	E	0.00251414204902577	1
341	E	A	All mutations	A	1.0	1
341	E	S	All mutations	S	2.0	>1
341	E	N	All mutations	N	1.9974858579509742	>1
341	E	R	All mutations	R	2.0	>1
341	E	Y	All mutations	Y	1.9974858579509742	>1
341	E	T	All mutations	T	2.0	>1
341	E	H	All mutations	H	1.9974858579509742	>1
341	E	L	All mutations	L	2.0	>1
341	E	F	All mutations	F	2.9974858579509744	>1
341	E	D	All mutations	D	0.9974858579509742	1
341	E	W	All mutations	W	2.8302954116907606	>1
341	E	V	All mutations	V	1.0	1
341	E	K	All mutations	K	1.0025141420490258	1
341	E	G	All mutations	G	1.0	1
341	E	I	All mutations	I	2.1697045883092394	>1
341	E	P	All mutations	P	2.0	>1
341	E	Q	All mutations	Q	1.0025141420490258	1
342	E	G	All mutations	G	1.0012570710245128	1
342	E	S	All mutations	S	2.0	>1
342	E	P	All mutations	P	2.0	>1
342	E	F	All mutations	F	2.998742928975487	>1
342	E	E	All mutations	E	0.00251414204902577	1
342	E	T	All mutations	T	1.9987429289754872	>1
342	E	R	All mutations	R	1.9987429289754872	>1
342	E	L	All mutations	L	2.0	>1
342	E	K	All mutations	K	1.0	1
342	E	V	All mutations	V	1.0012570710245128	1
342	E	D	All mutations	D	1.0	1
342	E	W	All mutations	W	2.7806411062225016	>1
342	E	C	All mutations	C	2.998742928975487	>1
342	E	I	All mutations	I	2.2181018227529856	>1
342	E	Y	All mutations	Y	1.9987429289754872	>1
342	E	Q	All mutations	Q	1.0012570710245128	1
342	E	M	All mutations	M	2.779384035197989	>1
342	E	H	All mutations	H	1.9987429289754872	>1
342	E	A	All mutations	A	1.0012570710245128	1
342	E	N	All mutations	N	1.9974858579509742	>1
343	E	C	All mutations	C	3.0	>1
343	E	M	All mutations	M	2.9484600879949716	>1
343	E	S	All mutations	S	2.0	>1
343	E	W	All mutations	W	2.9484600879949716	>1
343	E	K	All mutations	K	1.0	1
343	E	V	All mutations	V	1.0	1
343	E	I	All mutations	I	2.0515399120050284	>1
343	E	T	All mutations	T	2.0	>1
343	E	D	All mutations	D	1.0	1
343	E	F	All mutations	F	3.0	>1
343	E	P	All mutations	P	2.0	>1
343	E	Y	All mutations	Y	2.0	>1
343	E	E	All mutations	E	0.0	0
343	E	N	All mutations	N	2.0	>1
343	E	H	All mutations	H	2.0	>1
343	E	L	All mutations	L	2.0	>1
343	E	G	All mutations	G	1.0	1
343	E	Q	All mutations	Q	1.0	1
343	E	R	All mutations	R	2.0	>1
343	E	A	All mutations	A	1.0	1
344	V	C	All mutations	C	2.993086109365179	>1
344	V	Y	All mutations	Y	2.993086109365179	>1
344	V	N	All mutations	N	2.9798868636077938	>1
344	V	E	All mutations	E	1.0219987429289754	1
344	V	V	All mutations	V	0.01571338780641106	1
344	V	P	All mutations	P	1.9987429289754872	>1
344	V	D	All mutations	D	2.0094280326838465	>1
344	V	S	All mutations	S	1.9993714644877436	>1
344	V	H	All mutations	H	2.992457573852923	>1
344	V	T	All mutations	T	1.9861722187303583	>1
344	V	K	All mutations	K	1.9924575738529227	>1
344	V	W	All mutations	W	2.0219987429289756	>1
344	V	R	All mutations	R	1.9849151477058453	>1
344	V	A	All mutations	A	1.015713387806411	1
344	V	Q	All mutations	Q	2.0050282840980516	>1
344	V	I	All mutations	I	1.9635449402891263	>1
344	V	G	All mutations	G	1.015713387806411	1
344	V	L	All mutations	L	0.9981143934632307	1
344	V	F	All mutations	F	1.993086109365179	>1
344	V	M	All mutations	M	1.0087994971715901	1
345	L	D	All mutations	D	2.011313639220616	>1
345	L	R	All mutations	R	1.0	1
345	L	G	All mutations	G	2.0	>1
345	L	T	All mutations	T	2.0	>1
345	L	A	All mutations	A	2.0	>1
345	L	F	All mutations	F	1.011313639220616	1
345	L	Y	All mutations	Y	2.011313639220616	>1
345	L	C	All mutations	C	2.011313639220616	>1
345	L	V	All mutations	V	1.0	1
345	L	N	All mutations	N	2.011313639220616	>1
345	L	W	All mutations	W	2.998742928975487	>1
345	L	H	All mutations	H	1.011313639220616	1
345	L	L	All mutations	L	0.0	0
345	L	I	All mutations	I	1.0012570710245128	1
345	L	Q	All mutations	Q	1.988686360779384	>1
345	L	M	All mutations	M	1.9987429289754872	>1
345	L	E	All mutations	E	2.988686360779384	>1
345	L	K	All mutations	K	2.988686360779384	>1
345	L	S	All mutations	S	2.0	>1
345	L	P	All mutations	P	1.0	1
346	T	P	All mutations	P	0.9993714644877436	1
346	T	V	All mutations	V	2.0	>1
346	T	K	All mutations	K	1.0584538026398491	1
346	T	A	All mutations	A	1.0	1
346	T	I	All mutations	I	1.4921433060967946	>1
346	T	T	All mutations	T	0.0006285355122564425	1
346	T	W	All mutations	W	2.508485229415462	>1
346	T	C	All mutations	C	2.9421747328724073	>1
346	T	D	All mutations	D	2.9421747328724073	>1
346	T	G	All mutations	G	2.0	>1
346	T	L	All mutations	L	1.9993714644877436	>1
346	T	M	All mutations	M	1.5091137649277184	>1
346	T	H	All mutations	H	2.9415461973601507	>1
346	T	Y	All mutations	Y	2.9421747328724073	>1
346	T	S	All mutations	S	1.0	1
346	T	R	All mutations	R	1.0578252671275927	1
346	T	Q	All mutations	Q	2.057196731615336	>1
346	T	F	All mutations	F	2.9421747328724073	>1
346	T	E	All mutations	E	2.0578252671275927	>1
346	T	N	All mutations	N	1.9428032683846637	>1
347	G	C	All mutations	C	1.0094280326838467	1
347	G	V	All mutations	V	1.0	1
347	G	H	All mutations	H	2.0094280326838465	>1
347	G	S	All mutations	S	1.0094280326838467	1
347	G	N	All mutations	N	2.0094280326838465	>1
347	G	Y	All mutations	Y	2.0094280326838465	>1
347	G	A	All mutations	A	1.0	1
347	G	P	All mutations	P	2.0	>1
347	G	D	All mutations	D	1.0094280326838467	1
347	G	L	All mutations	L	2.0	>1
347	G	E	All mutations	E	1.9905719673161533	>1
347	G	W	All mutations	W	1.9937146448774357	>1
347	G	Q	All mutations	Q	2.9905719673161535	>1
347	G	T	All mutations	T	2.0	>1
347	G	F	All mutations	F	2.0094280326838465	>1
347	G	K	All mutations	K	2.9905719673161535	>1
347	G	M	All mutations	M	2.9937146448774357	>1
347	G	I	All mutations	I	2.0062853551225643	>1
347	G	G	All mutations	G	0.0	0
347	G	R	All mutations	R	1.0	1
348	N	F	All mutations	F	2.0	>1
348	N	M	All mutations	M	2.0	>1
348	N	I	All mutations	I	1.0	1
348	N	P	All mutations	P	2.0	>1
348	N	K	All mutations	K	1.0	1
348	N	Q	All mutations	Q	2.0	>1
348	N	N	All mutations	N	0.0	0
348	N	V	All mutations	V	2.0	>1
348	N	L	All mutations	L	2.0	>1
348	N	W	All mutations	W	3.0	>1
348	N	D	All mutations	D	1.0	1
348	N	S	All mutations	S	1.0	1
348	N	E	All mutations	E	2.0	>1
348	N	T	All mutations	T	1.0	1
348	N	H	All mutations	H	1.0	1
348	N	R	All mutations	R	2.0	>1
348	N	A	All mutations	A	2.0	>1
348	N	G	All mutations	G	2.0	>1
348	N	Y	All mutations	Y	1.0	1
348	N	C	All mutations	C	2.0	>1
349	L	R	All mutations	R	1.0	1
349	L	K	All mutations	K	2.9918290383406663	>1
349	L	C	All mutations	C	2.0081709616593337	>1
349	L	Q	All mutations	Q	1.9918290383406663	>1
349	L	D	All mutations	D	2.0081709616593337	>1
349	L	I	All mutations	I	1.0075424261470773	1
349	L	E	All mutations	E	2.9918290383406663	>1
349	L	G	All mutations	G	2.0	>1
349	L	N	All mutations	N	2.0081709616593337	>1
349	L	P	All mutations	P	1.0	1
349	L	Y	All mutations	Y	2.0081709616593337	>1
349	L	S	All mutations	S	2.0	>1
349	L	H	All mutations	H	1.0081709616593337	1
349	L	M	All mutations	M	1.9924575738529227	>1
349	L	L	All mutations	L	0.0	0
349	L	T	All mutations	T	2.0	>1
349	L	W	All mutations	W	2.992457573852923	>1
349	L	F	All mutations	F	1.0081709616593337	1
349	L	A	All mutations	A	2.0	>1
349	L	V	All mutations	V	1.0	1
350	Q	Y	All mutations	Y	2.0	>1
350	Q	L	All mutations	L	1.0	1
350	Q	V	All mutations	V	2.0	>1
350	Q	I	All mutations	I	2.0659962287869265	>1
350	Q	D	All mutations	D	2.0	>1
350	Q	W	All mutations	W	2.9340037712130735	>1
350	Q	N	All mutations	N	2.0	>1
350	Q	T	All mutations	T	2.0	>1
350	Q	A	All mutations	A	2.0	>1
350	Q	H	All mutations	H	1.0	1
350	Q	F	All mutations	F	3.0	>1
350	Q	C	All mutations	C	3.0	>1
350	Q	E	All mutations	E	1.0	1
350	Q	P	All mutations	P	1.0	1
350	Q	R	All mutations	R	1.0	1
350	Q	K	All mutations	K	1.0	1
350	Q	M	All mutations	M	2.9340037712130735	>1
350	Q	S	All mutations	S	2.0	>1
350	Q	Q	All mutations	Q	0.0	0
350	Q	G	All mutations	G	2.0	>1
351	T	E	All mutations	E	1.994343180389692	>1
351	T	S	All mutations	S	0.9993714644877436	1
351	T	R	All mutations	R	1.0062853551225643	1
351	T	Y	All mutations	Y	2.9993714644877434	>1
351	T	N	All mutations	N	2.0062853551225643	>1
351	T	L	All mutations	L	1.9993714644877436	>1
351	T	H	All mutations	H	3.0	>1
351	T	C	All mutations	C	2.9993714644877434	>1
351	T	Q	All mutations	Q	2.0	>1
351	T	M	All mutations	M	2.003142677561282	>1
351	T	D	All mutations	D	2.994343180389692	>1
351	T	I	All mutations	I	1.0094280326838467	1
351	T	F	All mutations	F	2.9993714644877434	>1
351	T	W	All mutations	W	2.996228786926461	>1
351	T	P	All mutations	P	1.0	1
351	T	G	All mutations	G	1.994343180389692	>1
351	T	K	All mutations	K	1.0062853551225643	1
351	T	T	All mutations	T	0.006285355122564425	1
351	T	A	All mutations	A	0.994343180389692	1
351	T	V	All mutations	V	1.994343180389692	>1
352	L	K	All mutations	K	2.0	>1
352	L	S	All mutations	S	1.0760527969830296	1
352	L	T	All mutations	T	2.0	>1
352	L	M	All mutations	M	1.0842237586423633	1
352	L	E	All mutations	E	2.0	>1
352	L	F	All mutations	F	1.0760527969830296	1
352	L	Q	All mutations	Q	1.9239472030169704	>1
352	L	P	All mutations	P	1.9239472030169704	>1
352	L	G	All mutations	G	2.0	>1
352	L	Y	All mutations	Y	2.0760527969830296	>1
352	L	W	All mutations	W	1.160276555625393	>1
352	L	N	All mutations	N	3.0	>1
352	L	L	All mutations	L	0.0	0
352	L	A	All mutations	A	2.0	>1
352	L	C	All mutations	C	2.0760527969830296	>1
352	L	D	All mutations	D	3.0	>1
352	L	I	All mutations	I	1.9157762413576367	>1
352	L	H	All mutations	H	2.9239472030169704	>1
352	L	V	All mutations	V	1.0	1
352	L	R	All mutations	R	1.9239472030169704	>1
353	K	T	All mutations	T	1.0	1
353	K	N	All mutations	N	1.011313639220616	1
353	K	H	All mutations	H	2.011313639220616	>1
353	K	F	All mutations	F	3.0	>1
353	K	A	All mutations	A	2.0	>1
353	K	L	All mutations	L	2.0	>1
353	K	D	All mutations	D	2.011313639220616	>1
353	K	V	All mutations	V	2.0	>1
353	K	I	All mutations	I	1.0194846008799496	1
353	K	Q	All mutations	Q	1.011313639220616	1
353	K	P	All mutations	P	2.0	>1
353	K	K	All mutations	K	0.011313639220615965	1
353	K	W	All mutations	W	2.9692017598994345	>1
353	K	Y	All mutations	Y	2.011313639220616	>1
353	K	G	All mutations	G	1.988686360779384	>1
353	K	C	All mutations	C	2.988686360779384	>1
353	K	R	All mutations	R	0.988686360779384	1
353	K	M	All mutations	M	1.9805153991200504	>1
353	K	E	All mutations	E	1.011313639220616	1
353	K	S	All mutations	S	1.988686360779384	>1
354	I	L	All mutations	L	0.9798868636077939	1
354	I	P	All mutations	P	2.0	>1
354	I	E	All mutations	E	1.9937146448774357	>1
354	I	T	All mutations	T	1.027027027027027	1
354	I	Q	All mutations	Q	2.0006285355122566	>1
354	I	R	All mutations	R	1.0276555625392834	1
354	I	H	All mutations	H	2.9993714644877434	>1
354	I	G	All mutations	G	1.993086109365179	>1
354	I	I	All mutations	I	0.04022627278441232	1
354	I	S	All mutations	S	1.9792583280955374	>1
354	I	W	All mutations	W	2.9666876178504085	>1
354	I	N	All mutations	N	2.0263984915147706	>1
354	I	Y	All mutations	Y	2.9792583280955376	>1
354	I	C	All mutations	C	2.9792583280955376	>1
354	I	F	All mutations	F	1.9792583280955374	>1
354	I	M	All mutations	M	1.0138277812696417	1
354	I	A	All mutations	A	1.993086109365179	>1
354	I	K	All mutations	K	1.0276555625392834	1
354	I	D	All mutations	D	2.992457573852923	>1
354	I	V	All mutations	V	0.9930861093651792	1
355	R	T	All mutations	T	1.0257699560025142	1
355	R	K	All mutations	K	0.9949717159019484	1
355	R	R	All mutations	R	0.03205531112507857	1
355	R	W	All mutations	W	2.0081709616593337	>1
355	R	G	All mutations	G	1.0307982401005658	1
355	R	A	All mutations	A	1.9993714644877436	>1
355	R	F	All mutations	F	2.9993714644877434	>1
355	R	E	All mutations	E	1.9685732243871779	>1
355	R	I	All mutations	I	1.048397234443746	1
355	R	V	All mutations	V	1.9987429289754872	>1
355	R	D	All mutations	D	2.968573224387178	>1
355	R	M	All mutations	M	2.0018856065367694	>1
355	R	Y	All mutations	Y	2.9692017598994345	>1
355	R	L	All mutations	L	1.9742300439974858	>1
355	R	S	All mutations	S	1.0571967316153363	1
355	R	N	All mutations	N	1.9949717159019484	>1
355	R	Q	All mutations	Q	1.9440603394091767	>1
355	R	H	All mutations	H	2.9440603394091767	>1
355	R	P	All mutations	P	1.9748585795097422	>1
355	R	C	All mutations	C	2.031426775612822	>1
356	V	M	All mutations	M	1.7146448774355751	>1
356	V	R	All mutations	R	1.9402891263356379	>1
356	V	C	All mutations	C	2.996857322438718	>1
356	V	T	All mutations	T	1.9402891263356379	>1
356	V	A	All mutations	A	1.062225015713388	1
356	V	K	All mutations	K	1.9409176618478945	>1
356	V	I	All mutations	I	1.1659333752357008	>1
356	V	V	All mutations	V	0.06222501571338781	1
356	V	D	All mutations	D	2.0615964802011315	>1
356	V	Y	All mutations	Y	2.996857322438718	>1
356	V	L	All mutations	L	0.9974858579509742	1
356	V	N	All mutations	N	2.9396605908233817	>1
356	V	W	All mutations	W	2.7718416090509113	>1
356	V	E	All mutations	E	1.0628535512256443	1
356	V	H	All mutations	H	2.9993714644877434	>1
356	V	G	All mutations	G	1.062225015713388	1
356	V	F	All mutations	F	1.9968573224387178	>1
356	V	Q	All mutations	Q	2.0006285355122566	>1
356	V	P	All mutations	P	2.0	>1
356	V	S	All mutations	S	1.9974858579509742	>1
357	H	H	All mutations	H	0.003771213073538655	1
357	H	G	All mutations	G	2.0	>1
357	H	P	All mutations	P	1.0037712130735386	1
357	H	R	All mutations	R	1.0037712130735386	1
357	H	W	All mutations	W	2.9974858579509744	>1
357	H	L	All mutations	L	1.0037712130735386	1
357	H	F	All mutations	F	1.9974858579509742	>1
357	H	A	All mutations	A	2.0	>1
357	H	M	All mutations	M	2.998742928975487	>1
357	H	C	All mutations	C	1.9974858579509742	>1
357	H	I	All mutations	I	1.9987429289754872	>1
357	H	K	All mutations	K	1.9987429289754872	>1
357	H	D	All mutations	D	1.0	1
357	H	T	All mutations	T	1.9987429289754872	>1
357	H	N	All mutations	N	0.9987429289754871	1
357	H	Y	All mutations	Y	0.9974858579509742	1
357	H	V	All mutations	V	2.0	>1
357	H	E	All mutations	E	2.0	>1
357	H	S	All mutations	S	1.9962287869264614	>1
357	H	Q	All mutations	Q	1.0037712130735386	1
358	E	N	All mutations	N	2.0006285355122566	>1
358	E	G	All mutations	G	1.0094280326838467	1
358	E	P	All mutations	P	1.9899434318038969	>1
358	E	Y	All mutations	Y	2.001257071024513	>1
358	E	D	All mutations	D	1.0119421747328725	1
358	E	I	All mutations	I	2.6511627906976742	>1
358	E	L	All mutations	L	1.9893148962916405	>1
358	E	H	All mutations	H	1.9912005028284099	>1
358	E	F	All mutations	F	2.998742928975487	>1
358	E	V	All mutations	V	1.0100565681961031	1
358	E	T	All mutations	T	1.9993714644877436	>1
358	E	A	All mutations	A	1.0106851037083595	1
358	E	K	All mutations	K	1.0018856065367694	1
358	E	W	All mutations	W	2.3463230672532998	>1
358	E	C	All mutations	C	2.9981143934632306	>1
358	E	E	All mutations	E	0.013199245757385292	1
358	E	M	All mutations	M	2.3463230672532998	>1
358	E	R	All mutations	R	1.9880578252671275	>1
358	E	Q	All mutations	Q	0.9924575738529227	1
358	E	S	All mutations	S	2.0	>1
359	G	Y	All mutations	Y	2.9974858579509744	>1
359	G	M	All mutations	M	2.3343808925204272	>1
359	G	P	All mutations	P	2.0	>1
359	G	R	All mutations	R	1.0	1
359	G	L	All mutations	L	2.0	>1
359	G	I	All mutations	I	2.6656191074795728	>1
359	G	G	All mutations	G	0.0	0
359	G	S	All mutations	S	1.9974858579509742	>1
359	G	W	All mutations	W	1.3343808925204275	>1
359	G	K	All mutations	K	2.0025141420490256	>1
359	G	N	All mutations	N	2.9974858579509744	>1
359	G	D	All mutations	D	1.9974858579509742	>1
359	G	T	All mutations	T	2.0	>1
359	G	E	All mutations	E	1.0025141420490258	1
359	G	H	All mutations	H	2.9974858579509744	>1
359	G	C	All mutations	C	1.9974858579509742	>1
359	G	Q	All mutations	Q	2.0025141420490256	>1
359	G	V	All mutations	V	1.0	1
359	G	F	All mutations	F	2.9974858579509744	>1
359	G	A	All mutations	A	1.0	1
360	Y	M	All mutations	M	3.0	>1
360	Y	W	All mutations	W	1.9993714644877436	>1
360	Y	I	All mutations	I	2.0	>1
360	Y	S	All mutations	S	1.0006285355122564	1
360	Y	Y	All mutations	Y	0.0018856065367693275	1
360	Y	A	All mutations	A	2.0	>1
360	Y	D	All mutations	D	1.0012570710245128	1
360	Y	T	All mutations	T	2.0	>1
360	Y	V	All mutations	V	2.0	>1
360	Y	F	All mutations	F	1.0006285355122564	1
360	Y	E	All mutations	E	2.001257071024513	>1
360	Y	Q	All mutations	Q	2.0006285355122566	>1
360	Y	L	All mutations	L	1.9993714644877436	>1
360	Y	C	All mutations	C	0.9993714644877436	1
360	Y	H	All mutations	H	1.0006285355122564	1
360	Y	N	All mutations	N	1.0012570710245128	1
360	Y	G	All mutations	G	1.9987429289754872	>1
360	Y	P	All mutations	P	1.9993714644877436	>1
360	Y	R	All mutations	R	1.9981143934632306	>1
360	Y	K	All mutations	K	2.001257071024513	>1
361	E	D	All mutations	D	1.0	1
361	E	L	All mutations	L	2.0	>1
361	E	I	All mutations	I	2.3318667504714017	>1
361	E	G	All mutations	G	1.0	1
361	E	R	All mutations	R	2.0	>1
361	E	A	All mutations	A	1.0	1
361	E	H	All mutations	H	2.0	>1
361	E	T	All mutations	T	2.0	>1
361	E	V	All mutations	V	1.0	1
361	E	C	All mutations	C	3.0	>1
361	E	K	All mutations	K	1.0	1
361	E	Y	All mutations	Y	2.0	>1
361	E	E	All mutations	E	0.0	0
361	E	S	All mutations	S	2.0	>1
361	E	M	All mutations	M	2.6681332495285983	>1
361	E	W	All mutations	W	2.6681332495285983	>1
361	E	F	All mutations	F	3.0	>1
361	E	Q	All mutations	Q	1.0	1
361	E	N	All mutations	N	2.0	>1
361	E	P	All mutations	P	2.0	>1
362	E	Y	All mutations	Y	2.0	>1
362	E	C	All mutations	C	3.0	>1
362	E	M	All mutations	M	2.4550597108736643	>1
362	E	V	All mutations	V	1.0	1
362	E	W	All mutations	W	2.4550597108736643	>1
362	E	T	All mutations	T	2.0	>1
362	E	R	All mutations	R	2.0	>1
362	E	Q	All mutations	Q	1.0	1
362	E	N	All mutations	N	2.0	>1
362	E	H	All mutations	H	2.0	>1
362	E	K	All mutations	K	1.0	1
362	E	G	All mutations	G	1.0	1
362	E	S	All mutations	S	2.0	>1
362	E	F	All mutations	F	3.0	>1
362	E	E	All mutations	E	0.0	0
362	E	I	All mutations	I	2.5449402891263357	>1
362	E	P	All mutations	P	2.0	>1
362	E	D	All mutations	D	1.0	1
362	E	A	All mutations	A	1.0	1
362	E	L	All mutations	L	2.0	>1
363	F	E	All mutations	E	2.9993714644877434	>1
363	F	N	All mutations	N	2.0006285355122566	>1
363	F	H	All mutations	H	2.0006285355122566	>1
363	F	D	All mutations	D	2.0006285355122566	>1
363	F	C	All mutations	C	1.0006285355122564	1
363	F	T	All mutations	T	2.0	>1
363	F	R	All mutations	R	2.0	>1
363	F	K	All mutations	K	2.9993714644877434	>1
363	F	P	All mutations	P	2.0	>1
363	F	G	All mutations	G	2.0	>1
363	F	S	All mutations	S	1.0	1
363	F	V	All mutations	V	1.0	1
363	F	L	All mutations	L	0.9993714644877436	1
363	F	W	All mutations	W	2.0	>1
363	F	F	All mutations	F	0.0006285355122564425	1
363	F	M	All mutations	M	2.0	>1
363	F	I	All mutations	I	1.0	1
363	F	Q	All mutations	Q	2.9993714644877434	>1
363	F	A	All mutations	A	2.0	>1
363	F	Y	All mutations	Y	1.0006285355122564	1
364	T	M	All mutations	M	1.9742300439974858	>1
364	T	I	All mutations	I	1.0245128849780012	1
364	T	S	All mutations	S	1.0006285355122564	1
364	T	G	All mutations	G	2.0	>1
364	T	F	All mutations	F	2.9880578252671275	>1
364	T	N	All mutations	N	1.988686360779384	>1
364	T	H	All mutations	H	2.988686360779384	>1
364	T	D	All mutations	D	2.988686360779384	>1
364	T	V	All mutations	V	1.9993714644877436	>1
364	T	Q	All mutations	Q	2.011313639220616	>1
364	T	C	All mutations	C	2.988686360779384	>1
364	T	R	All mutations	R	1.011313639220616	1
364	T	Y	All mutations	Y	2.988686360779384	>1
364	T	W	All mutations	W	2.974858579509742	>1
364	T	A	All mutations	A	1.0006285355122564	1
364	T	E	All mutations	E	2.011313639220616	>1
364	T	P	All mutations	P	1.0006285355122564	1
364	T	L	All mutations	L	1.9993714644877436	>1
364	T	T	All mutations	T	0.0006285355122564425	1
364	T	K	All mutations	K	1.011313639220616	1
365	M	Y	All mutations	Y	2.9993714644877434	>1
365	M	P	All mutations	P	2.0	>1
365	M	G	All mutations	G	2.0	>1
365	M	C	All mutations	C	2.9993714644877434	>1
365	M	I	All mutations	I	0.9962287869264613	1
365	M	D	All mutations	D	2.9993714644877434	>1
365	M	N	All mutations	N	1.9993714644877436	>1
365	M	S	All mutations	S	1.9993714644877436	>1
365	M	L	All mutations	L	1.0	1
365	M	W	All mutations	W	2.003771213073539	>1
365	M	R	All mutations	R	1.0006285355122564	1
365	M	K	All mutations	K	1.0006285355122564	1
365	M	A	All mutations	A	2.0	>1
365	M	H	All mutations	H	2.9993714644877434	>1
365	M	M	All mutations	M	0.003771213073538655	1
365	M	E	All mutations	E	2.0006285355122566	>1
365	M	Q	All mutations	Q	2.0006285355122566	>1
365	M	V	All mutations	V	1.0	1
365	M	F	All mutations	F	1.9993714644877436	>1
365	M	T	All mutations	T	1.0	1
366	V	H	All mutations	H	2.0603394091766183	>1
366	V	W	All mutations	W	2.94343180389692	>1
366	V	E	All mutations	E	1.9396605908233815	>1
366	V	S	All mutations	S	2.0	>1
366	V	V	All mutations	V	0.0	0
366	V	N	All mutations	N	2.0603394091766183	>1
366	V	F	All mutations	F	1.0603394091766185	1
366	V	D	All mutations	D	1.0603394091766185	1
366	V	R	All mutations	R	2.0	>1
366	V	C	All mutations	C	2.0603394091766183	>1
366	V	L	All mutations	L	1.0	1
366	V	Q	All mutations	Q	2.9396605908233817	>1
366	V	I	All mutations	I	1.0565681961030797	1
366	V	T	All mutations	T	2.0	>1
366	V	M	All mutations	M	1.9434318038969203	>1
366	V	P	All mutations	P	2.0	>1
366	V	G	All mutations	G	1.0	1
366	V	Y	All mutations	Y	2.0603394091766183	>1
366	V	K	All mutations	K	2.9396605908233817	>1
366	V	A	All mutations	A	1.0	1
367	G	W	All mutations	W	1.366436203645506	>1
367	G	L	All mutations	L	2.0	>1
367	G	D	All mutations	D	1.9968573224387178	>1
367	G	I	All mutations	I	2.633563796354494	>1
367	G	K	All mutations	K	2.003142677561282	>1
367	G	P	All mutations	P	2.0	>1
367	G	G	All mutations	G	0.0	0
367	G	R	All mutations	R	1.0	1
367	G	Q	All mutations	Q	2.003142677561282	>1
367	G	T	All mutations	T	2.0	>1
367	G	N	All mutations	N	2.996857322438718	>1
367	G	V	All mutations	V	1.0	1
367	G	E	All mutations	E	1.0031426775612822	1
367	G	A	All mutations	A	1.0	1
367	G	F	All mutations	F	2.996857322438718	>1
367	G	H	All mutations	H	2.996857322438718	>1
367	G	M	All mutations	M	2.366436203645506	>1
367	G	S	All mutations	S	1.9968573224387178	>1
367	G	C	All mutations	C	1.9968573224387178	>1
367	G	Y	All mutations	Y	2.996857322438718	>1
368	R	W	All mutations	W	1.9654305468258957	>1
368	R	D	All mutations	D	2.9182903834066627	>1
368	R	I	All mutations	I	1.5820238843494658	>1
368	R	R	All mutations	R	0.08170961659333752	1
368	R	T	All mutations	T	1.4676304211187932	>1
368	R	Y	All mutations	Y	2.9201759899434316	>1
368	R	H	All mutations	H	2.454431175361408	>1
368	R	Q	All mutations	Q	1.4544311753614079	>1
368	R	F	All mutations	F	3.0	>1
368	R	E	All mutations	E	1.9182903834066625	>1
368	R	G	All mutations	G	1.077938403519799	1
368	R	C	All mutations	C	2.0798240100565684	>1
368	R	M	All mutations	M	2.3532369578881207	>1
368	R	S	All mutations	S	1.4789440603394093	>1
368	R	V	All mutations	V	1.9981143934632306	>1
368	R	L	All mutations	L	1.534255185417976	>1
368	R	A	All mutations	A	1.9981143934632306	>1
368	R	P	All mutations	P	1.534255185417976	>1
368	R	N	All mutations	N	2.387806411062225	>1
368	R	K	All mutations	K	1.387806411062225	>1
369	R	H	All mutations	H	2.983029541169076	>1
369	R	T	All mutations	T	1.0062853551225643	1
369	R	K	All mutations	K	0.9949717159019484	1
369	R	G	All mutations	G	1.0106851037083595	1
369	R	F	All mutations	F	3.0	>1
369	R	L	All mutations	L	1.994343180389692	>1
369	R	R	All mutations	R	0.011942174732872407	1
369	R	A	All mutations	A	1.9993714644877436	>1
369	R	P	All mutations	P	1.994343180389692	>1
369	R	M	All mutations	M	1.8535512256442488	>1
369	R	Q	All mutations	Q	1.9830295411690761	>1
369	R	C	All mutations	C	2.011313639220616	>1
369	R	V	All mutations	V	1.9993714644877436	>1
369	R	W	All mutations	W	1.8585795097423004	>1
369	R	Y	All mutations	Y	2.988686360779384	>1
369	R	E	All mutations	E	1.9880578252671275	>1
369	R	S	All mutations	S	1.0175989943431805	1
369	R	I	All mutations	I	1.15901948460088	>1
369	R	N	All mutations	N	1.9949717159019484	>1
369	R	D	All mutations	D	2.9880578252671275	>1
370	A	F	All mutations	F	2.931489629164048	>1
370	A	S	All mutations	S	0.9993714644877436	1
370	A	V	All mutations	V	1.0006285355122564	1
370	A	E	All mutations	E	1.0685103708359522	1
370	A	H	All mutations	H	2.932118164676304	>1
370	A	K	All mutations	K	2.067881835323696	>1
370	A	Q	All mutations	Q	2.067881835323696	>1
370	A	A	All mutations	A	0.0006285355122564425	1
370	A	Y	All mutations	Y	2.931489629164048	>1
370	A	M	All mutations	M	2.9912005028284097	>1
370	A	D	All mutations	D	1.9327467001885608	>1
370	A	I	All mutations	I	2.0087994971715903	>1
370	A	N	All mutations	N	2.932118164676304	>1
370	A	R	All mutations	R	2.0	>1
370	A	G	All mutations	G	1.0006285355122564	1
370	A	C	All mutations	C	2.931489629164048	>1
370	A	P	All mutations	P	1.0	1
370	A	T	All mutations	T	1.0	1
370	A	W	All mutations	W	2.9905719673161535	>1
370	A	L	All mutations	L	1.9993714644877436	>1
371	T	K	All mutations	K	1.0295411690760528	1
371	T	D	All mutations	D	2.9704588309239472	>1
371	T	C	All mutations	C	2.9704588309239472	>1
371	T	T	All mutations	T	0.0	0
371	T	I	All mutations	I	1.345065996228787	>1
371	T	E	All mutations	E	2.0295411690760528	>1
371	T	A	All mutations	A	1.0	1
371	T	N	All mutations	N	1.9704588309239472	>1
371	T	W	All mutations	W	2.654934003771213	>1
371	T	Y	All mutations	Y	2.9704588309239472	>1
371	T	G	All mutations	G	2.0	>1
371	T	R	All mutations	R	1.0295411690760528	1
371	T	V	All mutations	V	2.0	>1
371	T	L	All mutations	L	2.0	>1
371	T	M	All mutations	M	1.654934003771213	>1
371	T	Q	All mutations	Q	2.0295411690760528	>1
371	T	H	All mutations	H	2.9704588309239472	>1
371	T	F	All mutations	F	2.9704588309239472	>1
371	T	P	All mutations	P	1.0	1
371	T	S	All mutations	S	1.0	1
372	A	L	All mutations	L	2.0	>1
372	A	F	All mutations	F	2.0974230043997486	>1
372	A	K	All mutations	K	2.9025769956002514	>1
372	A	H	All mutations	H	2.0974230043997486	>1
372	A	M	All mutations	M	3.0	>1
372	A	Y	All mutations	Y	2.0974230043997486	>1
372	A	T	All mutations	T	1.0	1
372	A	W	All mutations	W	3.0	>1
372	A	V	All mutations	V	1.0	1
372	A	D	All mutations	D	1.0974230043997486	1
372	A	C	All mutations	C	2.0974230043997486	>1
372	A	Q	All mutations	Q	2.9025769956002514	>1
372	A	P	All mutations	P	1.0	1
372	A	R	All mutations	R	2.0	>1
372	A	S	All mutations	S	1.0	1
372	A	I	All mutations	I	2.0	>1
372	A	N	All mutations	N	2.0974230043997486	>1
372	A	A	All mutations	A	0.0	0
372	A	G	All mutations	G	1.0	1
372	A	E	All mutations	E	1.9025769956002514	>1
373	I	Y	All mutations	Y	2.022627278441232	>1
373	I	W	All mutations	W	3.0	>1
373	I	P	All mutations	P	1.994343180389692	>1
373	I	F	All mutations	F	1.022627278441232	1
373	I	I	All mutations	I	0.0056568196103079825	1
373	I	V	All mutations	V	1.0	1
373	I	G	All mutations	G	2.0	>1
373	I	K	All mutations	K	1.9830295411690761	>1
373	I	L	All mutations	L	0.994343180389692	1
373	I	Q	All mutations	Q	2.97171590194846	>1
373	I	A	All mutations	A	2.0	>1
373	I	R	All mutations	R	1.97171590194846	>1
373	I	D	All mutations	D	2.022627278441232	>1
373	I	N	All mutations	N	1.02828409805154	1
373	I	S	All mutations	S	1.02828409805154	1
373	I	E	All mutations	E	2.977372721558768	>1
373	I	C	All mutations	C	2.022627278441232	>1
373	I	T	All mutations	T	1.005656819610308	1
373	I	M	All mutations	M	1.005656819610308	1
373	I	H	All mutations	H	2.016970458830924	>1
374	L	V	All mutations	V	1.0	1
374	L	Q	All mutations	Q	1.5097423004399748	>1
374	L	P	All mutations	P	1.0659962287869265	1
374	L	A	All mutations	A	2.0	>1
374	L	F	All mutations	F	1.4952859836580767	>1
374	L	R	All mutations	R	1.062225015713388	1
374	L	M	All mutations	M	1.7963544940289127	>1
374	L	L	All mutations	L	0.00754242614707731	1
374	L	W	All mutations	W	2.740414833438089	>1
374	L	E	All mutations	E	2.4437460716530484	>1
374	L	C	All mutations	C	2.4952859836580767	>1
374	L	I	All mutations	I	1.1935889377749842	>1
374	L	N	All mutations	N	2.5512256442489	>1
374	L	S	All mutations	S	1.937774984286612	>1
374	L	Y	All mutations	Y	2.4952859836580767	>1
374	L	H	All mutations	H	1.622250157133878	>1
374	L	K	All mutations	K	2.438717787554997	>1
374	L	D	All mutations	D	2.5562539283469516	>1
374	L	G	All mutations	G	2.0	>1
374	L	T	All mutations	T	1.9949717159019484	>1
375	R	C	All mutations	C	2.0	>1
375	R	H	All mutations	H	2.994343180389692	>1
375	R	P	All mutations	P	1.9968573224387178	>1
375	R	D	All mutations	D	2.996228786926461	>1
375	R	F	All mutations	F	2.998742928975487	>1
375	R	A	All mutations	A	1.9987429289754872	>1
375	R	W	All mutations	W	1.0659962287869265	1
375	R	E	All mutations	E	1.9987429289754872	>1
375	R	G	All mutations	G	1.0	1
375	R	I	All mutations	I	1.9396605908233815	>1
375	R	N	All mutations	N	2.0018856065367694	>1
375	R	M	All mutations	M	1.0691389063482086	1
375	R	S	All mutations	S	1.0043997485857952	1
375	R	Y	All mutations	Y	2.9974858579509744	>1
375	R	K	All mutations	K	1.0043997485857952	1
375	R	T	All mutations	T	1.0043997485857952	1
375	R	R	All mutations	R	0.003771213073538655	1
375	R	Q	All mutations	Q	1.9968573224387178	>1
375	R	L	All mutations	L	1.9968573224387178	>1
375	R	V	All mutations	V	1.9987429289754872	>1
376	K	C	All mutations	C	2.998742928975487	>1
376	K	N	All mutations	N	1.0012570710245128	1
376	K	K	All mutations	K	0.001257071024512885	1
376	K	A	All mutations	A	2.0	>1
376	K	E	All mutations	E	1.0012570710245128	1
376	K	M	All mutations	M	1.6096794468887492	>1
376	K	V	All mutations	V	2.0	>1
376	K	F	All mutations	F	3.0	>1
376	K	T	All mutations	T	1.0	1
376	K	S	All mutations	S	1.9987429289754872	>1
376	K	W	All mutations	W	2.608422375864236	>1
376	K	D	All mutations	D	2.001257071024513	>1
376	K	R	All mutations	R	0.9987429289754871	1
376	K	L	All mutations	L	2.0	>1
376	K	I	All mutations	I	1.3903205531112508	>1
376	K	P	All mutations	P	2.0	>1
376	K	G	All mutations	G	1.9987429289754872	>1
376	K	Y	All mutations	Y	2.001257071024513	>1
376	K	H	All mutations	H	2.001257071024513	>1
376	K	Q	All mutations	Q	1.0012570710245128	1
377	A	I	All mutations	I	2.005656819610308	>1
377	A	G	All mutations	G	1.0006285355122564	1
377	A	T	All mutations	T	1.0006285355122564	1
377	A	H	All mutations	H	2.994343180389692	>1
377	A	L	All mutations	L	1.9987429289754872	>1
377	A	E	All mutations	E	1.0062853551225643	1
377	A	K	All mutations	K	2.005656819610308	>1
377	A	N	All mutations	N	2.994343180389692	>1
377	A	A	All mutations	A	0.001257071024512885	1
377	A	S	All mutations	S	1.0	1
377	A	Y	All mutations	Y	2.9937146448774357	>1
377	A	C	All mutations	C	2.9937146448774357	>1
377	A	M	All mutations	M	2.993086109365179	>1
377	A	F	All mutations	F	2.993086109365179	>1
377	A	W	All mutations	W	2.993086109365179	>1
377	A	V	All mutations	V	1.0	1
377	A	P	All mutations	P	1.0006285355122564	1
377	A	R	All mutations	R	2.0	>1
377	A	Q	All mutations	Q	2.005656819610308	>1
377	A	D	All mutations	D	1.9949717159019484	>1
378	T	C	All mutations	C	2.005656819610308	>1
378	T	M	All mutations	M	2.0006285355122566	>1
378	T	N	All mutations	N	1.0075424261470773	1
378	T	Y	All mutations	Y	2.0062853551225643	>1
378	T	T	All mutations	T	0.001257071024512885	1
378	T	D	All mutations	D	2.006913890634821	>1
378	T	H	All mutations	H	2.006913890634821	>1
378	T	I	All mutations	I	1.0006285355122564	1
378	T	L	All mutations	L	2.0	>1
378	T	E	All mutations	E	2.993086109365179	>1
378	T	A	All mutations	A	1.0006285355122564	1
378	T	S	All mutations	S	0.9987429289754871	1
378	T	G	All mutations	G	1.9993714644877436	>1
378	T	V	All mutations	V	2.0	>1
378	T	K	All mutations	K	1.9937146448774357	>1
378	T	F	All mutations	F	2.0062853551225643	>1
378	T	W	All mutations	W	2.998742928975487	>1
378	T	Q	All mutations	Q	2.993086109365179	>1
378	T	R	All mutations	R	1.9924575738529227	>1
378	T	P	All mutations	P	1.0006285355122564	1
379	R	H	All mutations	H	2.994343180389692	>1
379	R	W	All mutations	W	1.8359522313010685	>1
379	R	L	All mutations	L	1.9987429289754872	>1
379	R	Q	All mutations	Q	1.994343180389692	>1
379	R	M	All mutations	M	1.8328095537397864	>1
379	R	I	All mutations	I	1.1697045883092394	>1
379	R	S	All mutations	S	1.005656819610308	1
379	R	G	All mutations	G	1.0043997485857952	1
379	R	Y	All mutations	Y	2.995600251414205	>1
379	R	C	All mutations	C	2.004399748585795	>1
379	R	R	All mutations	R	0.0043997485857950975	1
379	R	V	All mutations	V	2.0	>1
379	R	N	All mutations	N	1.9968573224387178	>1
379	R	K	All mutations	K	0.9968573224387178	1
379	R	F	All mutations	F	3.0	>1
379	R	D	All mutations	D	2.995600251414205	>1
379	R	P	All mutations	P	1.9987429289754872	>1
379	R	T	All mutations	T	1.0012570710245128	1
379	R	E	All mutations	E	1.9956002514142048	>1
379	R	A	All mutations	A	2.0	>1
380	R	S	All mutations	S	1.0050282840980516	1
380	R	P	All mutations	P	1.9962287869264614	>1
380	R	M	All mutations	M	1.2576995600251415	>1
380	R	V	All mutations	V	2.0	>1
380	R	D	All mutations	D	2.998742928975487	>1
380	R	C	All mutations	C	2.001257071024513	>1
380	R	T	All mutations	T	1.0037712130735386	1
380	R	Q	All mutations	Q	1.9949717159019484	>1
380	R	L	All mutations	L	1.9962287869264614	>1
380	R	W	All mutations	W	1.2551854179761157	>1
380	R	I	All mutations	I	1.7498428661219358	>1
380	R	Y	All mutations	Y	2.998742928975487	>1
380	R	G	All mutations	G	1.0012570710245128	1
380	R	K	All mutations	K	1.0025141420490258	1
380	R	N	All mutations	N	2.0025141420490256	>1
380	R	H	All mutations	H	2.9949717159019484	>1
380	R	A	All mutations	A	2.0	>1
380	R	E	All mutations	E	1.9987429289754872	>1
380	R	F	All mutations	F	3.0	>1
380	R	R	All mutations	R	0.001257071024512885	1
381	L	R	All mutations	R	1.1866750471401635	>1
381	L	M	All mutations	M	1.0345694531741043	1
381	L	S	All mutations	S	1.8133249528598365	>1
381	L	K	All mutations	K	2.0	>1
381	L	W	All mutations	W	1.8497800125707102	>1
381	L	Q	All mutations	Q	1.190446260213702	>1
381	L	C	All mutations	C	2.811439346323067	>1
381	L	A	All mutations	A	2.0	>1
381	L	F	All mutations	F	1.8114393463230674	>1
381	L	I	All mutations	I	1.961659333752357	>1
381	L	E	All mutations	E	2.0018856065367694	>1
381	L	H	All mutations	H	2.1866750471401635	>1
381	L	Y	All mutations	Y	2.811439346323067	>1
381	L	P	All mutations	P	1.1885606536769326	>1
381	L	T	All mutations	T	1.9981143934632306	>1
381	L	V	All mutations	V	1.0	1
381	L	L	All mutations	L	0.0018856065367693275	1
381	L	G	All mutations	G	2.0	>1
381	L	N	All mutations	N	2.996228786926461	>1
381	L	D	All mutations	D	2.9981143934632306	>1
382	I	V	All mutations	V	0.9836580766813325	1
382	I	S	All mutations	S	1.0188560653676932	1
382	I	D	All mutations	D	1.9861722187303583	>1
382	I	I	All mutations	I	0.016341923318667503	1
382	I	T	All mutations	T	1.0163419233186675	1
382	I	F	All mutations	F	1.0025141420490258	1
382	I	G	All mutations	G	1.9836580766813325	>1
382	I	H	All mutations	H	2.0025141420490256	>1
382	I	Y	All mutations	Y	2.0025141420490256	>1
382	I	C	All mutations	C	2.0025141420490256	>1
382	I	N	All mutations	N	1.0188560653676932	1
382	I	K	All mutations	K	2.013827781269642	>1
382	I	M	All mutations	M	1.0163419233186675	1
382	I	R	All mutations	R	1.9974858579509742	>1
382	I	W	All mutations	W	3.0	>1
382	I	E	All mutations	E	2.9811439346323065	>1
382	I	Q	All mutations	Q	2.9974858579509744	>1
382	I	L	All mutations	L	1.0	1
382	I	A	All mutations	A	1.9836580766813325	>1
382	I	P	All mutations	P	2.0	>1
383	Q	N	All mutations	N	2.0	>1
383	Q	S	All mutations	S	2.0	>1
383	Q	E	All mutations	E	1.0	1
383	Q	L	All mutations	L	1.0	1
383	Q	D	All mutations	D	2.0	>1
383	Q	K	All mutations	K	1.0	1
383	Q	M	All mutations	M	2.423004399748586	>1
383	Q	P	All mutations	P	1.0	1
383	Q	G	All mutations	G	2.0	>1
383	Q	T	All mutations	T	2.0	>1
383	Q	F	All mutations	F	3.0	>1
383	Q	H	All mutations	H	1.0	1
383	Q	Q	All mutations	Q	0.0	0
383	Q	Y	All mutations	Y	2.0	>1
383	Q	C	All mutations	C	3.0	>1
383	Q	A	All mutations	A	2.0	>1
383	Q	I	All mutations	I	2.576995600251414	>1
383	Q	R	All mutations	R	1.0	1
383	Q	W	All mutations	W	2.423004399748586	>1
383	Q	V	All mutations	V	2.0	>1
384	L	G	All mutations	G	1.9993714644877436	>1
384	L	T	All mutations	T	2.0	>1
384	L	Y	All mutations	Y	2.488372093023256	>1
384	L	K	All mutations	K	2.05656819610308	>1
384	L	R	All mutations	R	1.4556882463859209	>1
384	L	L	All mutations	L	0.0006285355122564425	1
384	L	E	All mutations	E	2.0559396605908233	>1
384	L	W	All mutations	W	2.0729101194217474	>1
384	L	V	All mutations	V	0.9993714644877436	1
384	L	A	All mutations	A	1.9993714644877436	>1
384	L	M	All mutations	M	1.5279698302954117	>1
384	L	D	All mutations	D	2.942803268384664	>1
384	L	P	All mutations	P	1.4556882463859209	>1
384	L	H	All mutations	H	2.399120050282841	>1
384	L	F	All mutations	F	1.4883720930232558	>1
384	L	N	All mutations	N	2.94343180389692	>1
384	L	Q	All mutations	Q	1.5122564424890006	>1
384	L	I	All mutations	I	1.4720301697045883	>1
384	L	C	All mutations	C	2.488372093023256	>1
384	L	S	All mutations	S	1.5449402891263357	>1
385	I	D	All mutations	D	2.950345694531741	>1
385	I	T	All mutations	T	1.0	1
385	I	C	All mutations	C	2.950345694531741	>1
385	I	M	All mutations	M	1.0	1
385	I	A	All mutations	A	2.0	>1
385	I	R	All mutations	R	1.049654305468259	1
385	I	L	All mutations	L	1.0	1
385	I	W	All mutations	W	3.0	>1
385	I	Q	All mutations	Q	2.049654305468259	>1
385	I	K	All mutations	K	1.049654305468259	1
385	I	I	All mutations	I	0.0	0
385	I	P	All mutations	P	2.0	>1
385	I	N	All mutations	N	1.950345694531741	>1
385	I	E	All mutations	E	2.049654305468259	>1
385	I	H	All mutations	H	2.950345694531741	>1
385	I	Y	All mutations	Y	2.950345694531741	>1
385	I	V	All mutations	V	1.0	1
385	I	S	All mutations	S	1.950345694531741	>1
385	I	G	All mutations	G	2.0	>1
385	I	F	All mutations	F	1.950345694531741	>1
386	V	A	All mutations	A	0.9987429289754871	1
386	V	T	All mutations	T	1.9981143934632306	>1
386	V	H	All mutations	H	2.984286612193589	>1
386	V	Y	All mutations	Y	2.9836580766813325	>1
386	V	K	All mutations	K	2.015713387806411	>1
386	V	Q	All mutations	Q	2.015713387806411	>1
386	V	M	All mutations	M	1.7184160905091137	>1
386	V	D	All mutations	D	1.9849151477058453	>1
386	V	N	All mutations	N	2.984286612193589	>1
386	V	C	All mutations	C	2.9836580766813325	>1
386	V	P	All mutations	P	1.9981143934632306	>1
386	V	R	All mutations	R	2.0	>1
386	V	W	All mutations	W	2.715901948460088	>1
386	V	S	All mutations	S	1.9974858579509742	>1
386	V	F	All mutations	F	1.985543683218102	>1
386	V	V	All mutations	V	0.00251414204902577	1
386	V	I	All mutations	I	1.2853551225644249	>1
386	V	L	All mutations	L	1.0012570710245128	1
386	V	G	All mutations	G	1.0006285355122564	1
386	V	E	All mutations	E	1.0163419233186675	1
387	S	F	All mutations	F	2.0	>1
387	S	M	All mutations	M	2.0	>1
387	S	V	All mutations	V	2.0	>1
387	S	L	All mutations	L	2.0	>1
387	S	H	All mutations	H	2.0	>1
387	S	I	All mutations	I	1.0	1
387	S	K	All mutations	K	2.0	>1
387	S	Q	All mutations	Q	3.0	>1
387	S	R	All mutations	R	1.0	1
387	S	W	All mutations	W	2.0	>1
387	S	P	All mutations	P	2.0	>1
387	S	Y	All mutations	Y	2.0	>1
387	S	G	All mutations	G	1.0	1
387	S	E	All mutations	E	3.0	>1
387	S	D	All mutations	D	2.0	>1
387	S	A	All mutations	A	2.0	>1
387	S	N	All mutations	N	1.0	1
387	S	T	All mutations	T	1.0	1
387	S	C	All mutations	C	1.0	1
387	S	S	All mutations	S	0.0	0
388	G	N	All mutations	N	2.992457573852923	>1
388	G	L	All mutations	L	2.0	>1
388	G	T	All mutations	T	2.0	>1
388	G	C	All mutations	C	1.9924575738529227	>1
388	G	K	All mutations	K	2.007542426147077	>1
388	G	I	All mutations	I	2.3959773727215588	>1
388	G	Q	All mutations	Q	2.007542426147077	>1
388	G	R	All mutations	R	1.0	1
388	G	W	All mutations	W	1.6040226272784412	>1
388	G	D	All mutations	D	1.9924575738529227	>1
388	G	E	All mutations	E	1.0075424261470773	1
388	G	P	All mutations	P	2.0	>1
388	G	H	All mutations	H	2.992457573852923	>1
388	G	Y	All mutations	Y	2.992457573852923	>1
388	G	A	All mutations	A	1.0	1
388	G	G	All mutations	G	0.0	0
388	G	V	All mutations	V	1.0	1
388	G	M	All mutations	M	2.6040226272784412	>1
388	G	S	All mutations	S	1.9924575738529227	>1
388	G	F	All mutations	F	2.992457573852923	>1
389	R	R	All mutations	R	0.14896291640477688	1
389	R	W	All mutations	W	2.043997485857951	>1
389	R	F	All mutations	F	3.0	>1
389	R	C	All mutations	C	2.148962916404777	>1
389	R	D	All mutations	D	2.851037083595223	>1
389	R	I	All mutations	I	1.104965430546826	>1
389	R	G	All mutations	G	1.1489629164047768	>1
389	R	K	All mutations	K	0.8510370835952231	1
389	R	M	All mutations	M	1.895034569453174	>1
389	R	Y	All mutations	Y	2.851037083595223	>1
389	R	L	All mutations	L	2.0	>1
389	R	V	All mutations	V	2.0	>1
389	R	A	All mutations	A	2.0	>1
389	R	P	All mutations	P	2.0	>1
389	R	T	All mutations	T	1.0	1
389	R	Q	All mutations	Q	1.8510370835952232	>1
389	R	H	All mutations	H	2.851037083595223	>1
389	R	N	All mutations	N	1.8510370835952232	>1
389	R	S	All mutations	S	1.1489629164047768	>1
389	R	E	All mutations	E	1.8510370835952232	>1
390	D	P	All mutations	P	2.0	>1
390	D	N	All mutations	N	0.9302325581395349	1
390	D	M	All mutations	M	2.928975487115022	>1
390	D	I	All mutations	I	1.930232558139535	>1
390	D	G	All mutations	G	1.0703959773727216	1
390	D	T	All mutations	T	1.9296040226272784	>1
390	D	E	All mutations	E	1.069767441860465	1
390	D	S	All mutations	S	1.930232558139535	>1
390	D	Q	All mutations	Q	1.9993714644877436	>1
390	D	H	All mutations	H	1.0006285355122564	1
390	D	Y	All mutations	Y	1.0006285355122564	1
390	D	R	All mutations	R	1.9993714644877436	>1
390	D	V	All mutations	V	1.0703959773727216	1
390	D	D	All mutations	D	0.071024512884978	1
390	D	C	All mutations	C	2.0006285355122566	>1
390	D	L	All mutations	L	2.0	>1
390	D	W	All mutations	W	2.9993714644877434	>1
390	D	K	All mutations	K	1.928975487115022	>1
390	D	F	All mutations	F	2.0006285355122566	>1
390	D	A	All mutations	A	1.0703959773727216	1
391	E	Y	All mutations	Y	1.9956002514142048	>1
391	E	E	All mutations	E	0.0043997485857950975	1
391	E	C	All mutations	C	2.995600251414205	>1
391	E	Q	All mutations	Q	1.0043997485857952	1
391	E	T	All mutations	T	2.0	>1
391	E	H	All mutations	H	1.9956002514142048	>1
391	E	W	All mutations	W	2.3645505971087366	>1
391	E	G	All mutations	G	1.0	1
391	E	K	All mutations	K	1.0043997485857952	1
391	E	P	All mutations	P	2.0	>1
391	E	D	All mutations	D	0.9956002514142049	1
391	E	S	All mutations	S	2.0	>1
391	E	N	All mutations	N	1.9956002514142048	>1
391	E	M	All mutations	M	2.3645505971087366	>1
391	E	I	All mutations	I	2.6354494028912634	>1
391	E	F	All mutations	F	2.995600251414205	>1
391	E	L	All mutations	L	2.0	>1
391	E	V	All mutations	V	1.0	1
391	E	A	All mutations	A	1.0	1
391	E	R	All mutations	R	2.0	>1
392	Q	M	All mutations	M	2.4299182903834065	>1
392	Q	T	All mutations	T	2.0	>1
392	Q	Q	All mutations	Q	0.00251414204902577	1
392	Q	A	All mutations	A	2.0	>1
392	Q	H	All mutations	H	0.9974858579509742	1
392	Q	I	All mutations	I	2.5700817096165935	>1
392	Q	S	All mutations	S	2.0	>1
392	Q	D	All mutations	D	1.9974858579509742	>1
392	Q	E	All mutations	E	1.0025141420490258	1
392	Q	R	All mutations	R	1.0	1
392	Q	N	All mutations	N	1.9974858579509742	>1
392	Q	G	All mutations	G	2.0	>1
392	Q	P	All mutations	P	1.0	1
392	Q	L	All mutations	L	1.0	1
392	Q	C	All mutations	C	2.9974858579509744	>1
392	Q	W	All mutations	W	2.4299182903834065	>1
392	Q	V	All mutations	V	2.0	>1
392	Q	F	All mutations	F	2.9974858579509744	>1
392	Q	Y	All mutations	Y	1.9974858579509742	>1
392	Q	K	All mutations	K	1.0025141420490258	1
393	S	I	All mutations	I	2.013827781269642	>1
393	S	M	All mutations	M	2.986172218730358	>1
393	S	W	All mutations	W	1.988686360779384	>1
393	S	R	All mutations	R	2.0	>1
393	S	S	All mutations	S	0.00251414204902577	1
393	S	A	All mutations	A	0.9974858579509742	1
393	S	P	All mutations	P	1.0	1
393	S	K	All mutations	K	2.0163419233186675	>1
393	S	E	All mutations	E	2.013827781269642	>1
393	S	G	All mutations	G	1.9974858579509742	>1
393	S	Y	All mutations	Y	1.9861722187303583	>1
393	S	T	All mutations	T	1.0	1
393	S	Q	All mutations	Q	2.0163419233186675	>1
393	S	V	All mutations	V	1.9974858579509742	>1
393	S	L	All mutations	L	1.0188560653676932	1
393	S	N	All mutations	N	2.9836580766813325	>1
393	S	C	All mutations	C	1.9861722187303583	>1
393	S	H	All mutations	H	2.9836580766813325	>1
393	S	D	All mutations	D	2.9811439346323065	>1
393	S	F	All mutations	F	1.9861722187303583	>1
394	I	G	All mutations	G	1.9610307982401005	>1
394	I	A	All mutations	A	1.9604022627278441	>1
394	I	I	All mutations	I	0.039597737272155875	1
394	I	H	All mutations	H	2.0131992457573853	>1
394	I	C	All mutations	C	2.0131992457573853	>1
394	I	T	All mutations	T	1.038340666247643	1
394	I	P	All mutations	P	1.9993714644877436	>1
394	I	N	All mutations	N	1.0521684475172848	1
394	I	Q	All mutations	Q	2.9868007542426147	>1
394	I	L	All mutations	L	1.0006285355122564	1
394	I	M	All mutations	M	1.0395977372721559	1
394	I	R	All mutations	R	1.9880578252671275	>1
394	I	D	All mutations	D	1.9742300439974858	>1
394	I	Y	All mutations	Y	2.0131992457573853	>1
394	I	S	All mutations	S	1.0509113764927718	1
394	I	F	All mutations	F	1.0138277812696417	1
394	I	E	All mutations	E	2.9478315524827154	>1
394	I	V	All mutations	V	0.961659333752357	1
394	I	W	All mutations	W	3.0	>1
394	I	K	All mutations	K	2.025769956002514	>1
395	A	C	All mutations	C	2.003142677561282	>1
395	A	E	All mutations	E	1.9974858579509742	>1
395	A	K	All mutations	K	2.996228786926461	>1
395	A	I	All mutations	I	2.0	>1
395	A	G	All mutations	G	1.0006285355122564	1
395	A	V	All mutations	V	1.0006285355122564	1
395	A	Q	All mutations	Q	2.996857322438718	>1
395	A	Y	All mutations	Y	2.003142677561282	>1
395	A	W	All mutations	W	2.9993714644877434	>1
395	A	R	All mutations	R	2.0	>1
395	A	L	All mutations	L	2.0	>1
395	A	P	All mutations	P	1.0	1
395	A	F	All mutations	F	2.003142677561282	>1
395	A	N	All mutations	N	2.0025141420490256	>1
395	A	S	All mutations	S	1.0	1
395	A	H	All mutations	H	2.003142677561282	>1
395	A	A	All mutations	A	0.0006285355122564425	1
395	A	M	All mutations	M	2.998742928975487	>1
395	A	T	All mutations	T	0.9993714644877436	1
395	A	D	All mutations	D	1.0037712130735386	1
396	E	M	All mutations	M	2.77561282212445	>1
396	E	H	All mutations	H	2.0	>1
396	E	C	All mutations	C	3.0	>1
396	E	P	All mutations	P	2.0	>1
396	E	N	All mutations	N	2.0	>1
396	E	I	All mutations	I	2.22438717787555	>1
396	E	K	All mutations	K	1.0	1
396	E	A	All mutations	A	1.0	1
396	E	E	All mutations	E	0.0	0
396	E	W	All mutations	W	2.77561282212445	>1
396	E	F	All mutations	F	3.0	>1
396	E	D	All mutations	D	1.0	1
396	E	V	All mutations	V	1.0	1
396	E	S	All mutations	S	2.0	>1
396	E	T	All mutations	T	2.0	>1
396	E	Q	All mutations	Q	1.0	1
396	E	Y	All mutations	Y	2.0	>1
396	E	L	All mutations	L	2.0	>1
396	E	G	All mutations	G	1.0	1
396	E	R	All mutations	R	2.0	>1
397	A	R	All mutations	R	1.9993714644877436	>1
397	A	D	All mutations	D	1.9805153991200504	>1
397	A	M	All mutations	M	2.9113764927718417	>1
397	A	N	All mutations	N	2.9792583280955376	>1
397	A	G	All mutations	G	1.0006285355122564	1
397	A	T	All mutations	T	1.0006285355122564	1
397	A	K	All mutations	K	2.0194846008799496	>1
397	A	V	All mutations	V	0.9993714644877436	1
397	A	L	All mutations	L	1.9987429289754872	>1
397	A	W	All mutations	W	2.913262099308611	>1
397	A	H	All mutations	H	2.9798868636077938	>1
397	A	C	All mutations	C	2.9798868636077938	>1
397	A	I	All mutations	I	2.08485229415462	>1
397	A	P	All mutations	P	1.0012570710245128	1
397	A	S	All mutations	S	1.0012570710245128	1
397	A	Q	All mutations	Q	2.0201131363922062	>1
397	A	E	All mutations	E	1.0207416719044626	1
397	A	F	All mutations	F	2.978629792583281	>1
397	A	Y	All mutations	Y	2.9798868636077938	>1
397	A	A	All mutations	A	0.0018856065367693275	1
398	I	K	All mutations	K	1.5719673161533627	>1
398	I	S	All mutations	S	1.52294154619736	>1
398	I	R	All mutations	R	1.5216844751728473	>1
398	I	C	All mutations	C	2.475801382778127	>1
398	I	A	All mutations	A	1.951602765556254	>1
398	I	L	All mutations	L	0.9987429289754871	1
398	I	E	All mutations	E	2.4776869893148965	>1
398	I	H	All mutations	H	2.474544311753614	>1
398	I	N	All mutations	N	1.5273412947831553	>1
398	I	G	All mutations	G	1.9553739786297926	>1
398	I	M	All mutations	M	1.048397234443746	1
398	I	F	All mutations	F	1.4795725958516657	>1
398	I	D	All mutations	D	2.433060967944689	>1
398	I	I	All mutations	I	0.05845380263984915	1
398	I	Q	All mutations	Q	2.5191703331238213	>1
398	I	P	All mutations	P	1.993086109365179	>1
398	I	Y	All mutations	Y	2.475801382778127	>1
398	I	T	All mutations	T	1.0458830923947202	1
398	I	W	All mutations	W	2.993086109365179	>1
398	I	V	All mutations	V	0.9591451917033312	1
399	I	Y	All mutations	Y	2.245757385292269	>1
399	I	F	All mutations	F	1.245757385292269	>1
399	I	R	All mutations	R	1.754242614707731	>1
399	I	K	All mutations	K	1.754242614707731	>1
399	I	D	All mutations	D	2.245757385292269	>1
399	I	C	All mutations	C	2.245757385292269	>1
399	I	H	All mutations	H	2.245757385292269	>1
399	I	E	All mutations	E	2.754242614707731	>1
399	I	S	All mutations	S	1.245757385292269	>1
399	I	M	All mutations	M	1.0	1
399	I	A	All mutations	A	2.0	>1
399	I	L	All mutations	L	1.0	1
399	I	N	All mutations	N	1.245757385292269	>1
399	I	Q	All mutations	Q	2.754242614707731	>1
399	I	P	All mutations	P	2.0	>1
399	I	W	All mutations	W	3.0	>1
399	I	G	All mutations	G	2.0	>1
399	I	T	All mutations	T	1.0	1
399	I	I	All mutations	I	0.0	0
399	I	V	All mutations	V	1.0	1
400	V	S	All mutations	S	2.0	>1
400	V	F	All mutations	F	1.9993714644877436	>1
400	V	Q	All mutations	Q	2.0006285355122566	>1
400	V	K	All mutations	K	2.0	>1
400	V	D	All mutations	D	2.0	>1
400	V	V	All mutations	V	0.0006285355122564425	1
400	V	T	All mutations	T	1.9993714644877436	>1
400	V	Y	All mutations	Y	2.9993714644877434	>1
400	V	R	All mutations	R	1.9993714644877436	>1
400	V	E	All mutations	E	1.0012570710245128	1
400	V	I	All mutations	I	1.670647391577624	>1
400	V	W	All mutations	W	2.3287240729101195	>1
400	V	P	All mutations	P	2.0	>1
400	V	C	All mutations	C	2.9993714644877434	>1
400	V	N	All mutations	N	2.998742928975487	>1
400	V	H	All mutations	H	2.9993714644877434	>1
400	V	A	All mutations	A	1.0006285355122564	1
400	V	L	All mutations	L	1.0	1
400	V	G	All mutations	G	1.0006285355122564	1
400	V	M	All mutations	M	1.328095537397863	>1
401	A	S	All mutations	S	1.0	1
401	A	F	All mutations	F	2.497171590194846	>1
401	A	R	All mutations	R	2.0	>1
401	A	T	All mutations	T	1.0	1
401	A	Y	All mutations	Y	2.497171590194846	>1
401	A	N	All mutations	N	2.497171590194846	>1
401	A	C	All mutations	C	2.497171590194846	>1
401	A	G	All mutations	G	1.0	1
401	A	P	All mutations	P	1.0	1
401	A	W	All mutations	W	2.918918918918919	>1
401	A	M	All mutations	M	2.918918918918919	>1
401	A	D	All mutations	D	1.497171590194846	>1
401	A	A	All mutations	A	0.0	0
401	A	V	All mutations	V	1.0	1
401	A	I	All mutations	I	2.081081081081081	>1
401	A	K	All mutations	K	2.502828409805154	>1
401	A	L	All mutations	L	2.0	>1
401	A	Q	All mutations	Q	2.502828409805154	>1
401	A	H	All mutations	H	2.497171590194846	>1
401	A	E	All mutations	E	1.502828409805154	>1
402	L	V	All mutations	V	1.0006285355122564	1
402	L	L	All mutations	L	1.0006285355122564	1
402	L	R	All mutations	R	1.0	1
402	L	A	All mutations	A	1.9993714644877436	>1
402	L	D	All mutations	D	3.0	>1
402	L	G	All mutations	G	2.0	>1
402	L	C	All mutations	C	3.0	>1
402	L	T	All mutations	T	0.9993714644877436	1
402	L	Y	All mutations	Y	3.0	>1
402	L	P	All mutations	P	1.9993714644877436	>1
402	L	F	All mutations	F	2.0006285355122566	>1
402	L	N	All mutations	N	2.0	>1
402	L	W	All mutations	W	2.0	>1
402	L	M	All mutations	M	0.0006285355122564425	1
402	L	S	All mutations	S	1.9993714644877436	>1
402	L	I	All mutations	I	1.0006285355122564	1
402	L	Q	All mutations	Q	2.0	>1
402	L	K	All mutations	K	1.0	1
402	L	E	All mutations	E	2.0	>1
402	L	H	All mutations	H	3.0	>1
403	V	N	All mutations	N	2.9270898805782526	>1
403	V	K	All mutations	K	2.0729101194217474	>1
403	V	E	All mutations	E	1.0729101194217474	1
403	V	A	All mutations	A	1.0	1
403	V	F	All mutations	F	1.9270898805782526	>1
403	V	C	All mutations	C	2.9270898805782526	>1
403	V	G	All mutations	G	1.0	1
403	V	M	All mutations	M	1.6360779384035198	>1
403	V	Y	All mutations	Y	2.9270898805782526	>1
403	V	V	All mutations	V	0.0	0
403	V	H	All mutations	H	2.9270898805782526	>1
403	V	S	All mutations	S	2.0	>1
403	V	R	All mutations	R	2.0	>1
403	V	W	All mutations	W	2.63607793840352	>1
403	V	I	All mutations	I	1.3639220615964802	>1
403	V	Q	All mutations	Q	2.0729101194217474	>1
403	V	L	All mutations	L	1.0	1
403	V	D	All mutations	D	1.9270898805782526	>1
403	V	P	All mutations	P	2.0	>1
403	V	T	All mutations	T	2.0	>1
404	F	P	All mutations	P	2.0	>1
404	F	K	All mutations	K	3.0	>1
404	F	H	All mutations	H	2.0	>1
404	F	T	All mutations	T	2.0	>1
404	F	Q	All mutations	Q	3.0	>1
404	F	A	All mutations	A	2.0	>1
404	F	E	All mutations	E	3.0	>1
404	F	L	All mutations	L	1.0	1
404	F	D	All mutations	D	2.0	>1
404	F	R	All mutations	R	2.0	>1
404	F	Y	All mutations	Y	1.0	1
404	F	W	All mutations	W	2.0	>1
404	F	C	All mutations	C	1.0	1
404	F	S	All mutations	S	1.0	1
404	F	V	All mutations	V	1.0	1
404	F	M	All mutations	M	2.0	>1
404	F	F	All mutations	F	0.0	0
404	F	G	All mutations	G	2.0	>1
404	F	N	All mutations	N	2.0	>1
404	F	I	All mutations	I	1.0	1
405	S	S	All mutations	S	0.0	0
405	S	K	All mutations	K	2.0094280326838465	>1
405	S	H	All mutations	H	2.9905719673161535	>1
405	S	A	All mutations	A	1.0	1
405	S	P	All mutations	P	1.0	1
405	S	M	All mutations	M	2.983029541169076	>1
405	S	D	All mutations	D	2.9905719673161535	>1
405	S	Y	All mutations	Y	1.9905719673161533	>1
405	S	F	All mutations	F	1.9905719673161533	>1
405	S	W	All mutations	W	1.9830295411690761	>1
405	S	C	All mutations	C	1.9905719673161533	>1
405	S	I	All mutations	I	2.016970458830924	>1
405	S	R	All mutations	R	2.0	>1
405	S	N	All mutations	N	2.9905719673161535	>1
405	S	L	All mutations	L	1.0094280326838467	1
405	S	T	All mutations	T	1.0	1
405	S	E	All mutations	E	2.0094280326838465	>1
405	S	V	All mutations	V	2.0	>1
405	S	Q	All mutations	Q	2.0094280326838465	>1
405	S	G	All mutations	G	2.0	>1
406	Q	Y	All mutations	Y	2.0006285355122566	>1
406	Q	S	All mutations	S	2.0	>1
406	Q	D	All mutations	D	2.0006285355122566	>1
406	Q	K	All mutations	K	1.0006285355122564	1
406	Q	V	All mutations	V	2.0	>1
406	Q	F	All mutations	F	3.0	>1
406	Q	W	All mutations	W	2.7806411062225016	>1
406	Q	C	All mutations	C	2.9993714644877434	>1
406	Q	M	All mutations	M	2.781269641734758	>1
406	Q	G	All mutations	G	1.9993714644877436	>1
406	Q	N	All mutations	N	2.0006285355122566	>1
406	Q	R	All mutations	R	0.9993714644877436	1
406	Q	L	All mutations	L	1.0	1
406	Q	E	All mutations	E	1.0006285355122564	1
406	Q	P	All mutations	P	1.0	1
406	Q	Q	All mutations	Q	0.0006285355122564425	1
406	Q	I	All mutations	I	2.218730358265242	>1
406	Q	H	All mutations	H	1.0006285355122564	1
406	Q	A	All mutations	A	2.0	>1
406	Q	T	All mutations	T	2.0	>1
407	E	C	All mutations	C	3.0	>1
407	E	K	All mutations	K	1.0	1
407	E	L	All mutations	L	2.0	>1
407	E	G	All mutations	G	1.0	1
407	E	S	All mutations	S	2.0	>1
407	E	D	All mutations	D	1.0	1
407	E	P	All mutations	P	2.0	>1
407	E	I	All mutations	I	2.8686360779384037	>1
407	E	Q	All mutations	Q	1.0	1
407	E	F	All mutations	F	3.0	>1
407	E	W	All mutations	W	2.1313639220615963	>1
407	E	V	All mutations	V	1.0	1
407	E	M	All mutations	M	2.1313639220615963	>1
407	E	N	All mutations	N	2.0	>1
407	E	Y	All mutations	Y	2.0	>1
407	E	T	All mutations	T	2.0	>1
407	E	R	All mutations	R	2.0	>1
407	E	E	All mutations	E	0.0	0
407	E	A	All mutations	A	1.0	1
407	E	H	All mutations	H	2.0	>1
408	D	W	All mutations	W	2.9993714644877434	>1
408	D	N	All mutations	N	1.0006285355122564	1
408	D	P	All mutations	P	2.0	>1
408	D	C	All mutations	C	2.0006285355122566	>1
408	D	M	All mutations	M	2.9993714644877434	>1
408	D	L	All mutations	L	2.0	>1
408	D	E	All mutations	E	0.9993714644877436	1
408	D	F	All mutations	F	2.0006285355122566	>1
408	D	Q	All mutations	Q	1.9993714644877436	>1
408	D	T	All mutations	T	2.0	>1
408	D	I	All mutations	I	2.0006285355122566	>1
408	D	K	All mutations	K	1.9993714644877436	>1
408	D	V	All mutations	V	1.0	1
408	D	H	All mutations	H	1.0006285355122564	1
408	D	D	All mutations	D	0.0006285355122564425	1
408	D	R	All mutations	R	2.0	>1
408	D	S	All mutations	S	2.0	>1
408	D	Y	All mutations	Y	1.0006285355122564	1
408	D	A	All mutations	A	1.0	1
408	D	G	All mutations	G	1.0	1
409	C	Y	All mutations	Y	1.0138277812696417	1
409	C	S	All mutations	S	1.0	1
409	C	E	All mutations	E	3.0	>1
409	C	Q	All mutations	Q	2.986172218730358	>1
409	C	H	All mutations	H	1.9861722187303583	>1
409	C	P	All mutations	P	1.9861722187303583	>1
409	C	I	All mutations	I	2.0	>1
409	C	K	All mutations	K	3.0	>1
409	C	L	All mutations	L	1.9861722187303583	>1
409	C	V	All mutations	V	2.0	>1
409	C	A	All mutations	A	2.0	>1
409	C	G	All mutations	G	1.0	1
409	C	R	All mutations	R	0.9861722187303583	1
409	C	D	All mutations	D	2.0	>1
409	C	T	All mutations	T	2.0	>1
409	C	W	All mutations	W	1.0138277812696417	1
409	C	M	All mutations	M	3.0	>1
409	C	F	All mutations	F	1.0138277812696417	1
409	C	N	All mutations	N	2.0	>1
409	C	C	All mutations	C	0.013827781269641735	1
410	M	E	All mutations	E	1.9968573224387178	>1
410	M	Y	All mutations	Y	3.0	>1
410	M	L	All mutations	L	1.0	1
410	M	A	All mutations	A	1.9968573224387178	>1
410	M	N	All mutations	N	2.003142677561282	>1
410	M	H	All mutations	H	3.0	>1
410	M	I	All mutations	I	1.0031426775612822	1
410	M	S	All mutations	S	2.0	>1
410	M	G	All mutations	G	1.9968573224387178	>1
410	M	M	All mutations	M	0.0031426775612822125	1
410	M	R	All mutations	R	1.0031426775612822	1
410	M	D	All mutations	D	2.996857322438718	>1
410	M	C	All mutations	C	3.0	>1
410	M	V	All mutations	V	0.9968573224387178	1
410	M	K	All mutations	K	1.0031426775612822	1
410	M	Q	All mutations	Q	2.0	>1
410	M	W	All mutations	W	2.0	>1
410	M	F	All mutations	F	2.0	>1
410	M	P	All mutations	P	2.0	>1
410	M	T	All mutations	T	1.0031426775612822	1
411	I	R	All mutations	R	1.5047140163419233	>1
411	I	I	All mutations	I	0.06285355122564425	1
411	I	V	All mutations	V	0.9604022627278441	1
411	I	W	All mutations	W	2.983029541169076	>1
411	I	Y	All mutations	Y	2.5279698302954117	>1
411	I	T	All mutations	T	1.0446260213702074	1
411	I	D	All mutations	D	2.487743557510999	>1
411	I	S	All mutations	S	1.5348837209302326	>1
411	I	G	All mutations	G	1.9597737272155877	>1
411	I	A	All mutations	A	1.9591451917033313	>1
411	I	Q	All mutations	Q	2.4670018856065368	>1
411	I	E	All mutations	E	2.431803896920176	>1
411	I	P	All mutations	P	1.994343180389692	>1
411	I	L	All mutations	L	0.9956002514142049	1
411	I	H	All mutations	H	2.52294154619736	>1
411	I	F	All mutations	F	1.528598365807668	>1
411	I	K	All mutations	K	1.5172847265870522	>1
411	I	C	All mutations	C	2.5279698302954117	>1
411	I	M	All mutations	M	1.0289126335637964	1
411	I	N	All mutations	N	1.5732243871778755	>1
412	K	P	All mutations	P	2.0	>1
412	K	I	All mutations	I	1.7818981772470144	>1
412	K	M	All mutations	M	1.2181018227529856	>1
412	K	Y	All mutations	Y	2.0006285355122566	>1
412	K	Q	All mutations	Q	1.0006285355122564	1
412	K	V	All mutations	V	2.0	>1
412	K	S	All mutations	S	1.9993714644877436	>1
412	K	T	All mutations	T	1.0	1
412	K	N	All mutations	N	1.0006285355122564	1
412	K	F	All mutations	F	3.0	>1
412	K	W	All mutations	W	2.217473287240729	>1
412	K	K	All mutations	K	0.0006285355122564425	1
412	K	D	All mutations	D	2.0006285355122566	>1
412	K	E	All mutations	E	1.0006285355122564	1
412	K	L	All mutations	L	2.0	>1
412	K	A	All mutations	A	2.0	>1
412	K	C	All mutations	C	2.9993714644877434	>1
412	K	G	All mutations	G	1.9993714644877436	>1
412	K	R	All mutations	R	0.9993714644877436	1
412	K	H	All mutations	H	2.0006285355122566	>1
413	A	M	All mutations	M	2.985543683218102	>1
413	A	W	All mutations	W	2.986172218730358	>1
413	A	C	All mutations	C	2.9849151477058453	>1
413	A	K	All mutations	K	2.014456316781898	>1
413	A	E	All mutations	E	1.015713387806411	1
413	A	F	All mutations	F	2.9849151477058453	>1
413	A	N	All mutations	N	2.984286612193589	>1
413	A	L	All mutations	L	2.0	>1
413	A	T	All mutations	T	0.9993714644877436	1
413	A	Y	All mutations	Y	2.9849151477058453	>1
413	A	H	All mutations	H	2.9849151477058453	>1
413	A	G	All mutations	G	1.0006285355122564	1
413	A	R	All mutations	R	1.9993714644877436	>1
413	A	D	All mutations	D	1.985543683218102	>1
413	A	S	All mutations	S	1.0	1
413	A	P	All mutations	P	1.0	1
413	A	Q	All mutations	Q	2.0150848522941547	>1
413	A	A	All mutations	A	0.0006285355122564425	1
413	A	I	All mutations	I	2.0131992457573853	>1
413	A	V	All mutations	V	1.0006285355122564	1
414	V	E	All mutations	E	1.727215587680704	>1
414	V	T	All mutations	T	2.0	>1
414	V	Q	All mutations	Q	2.727215587680704	>1
414	V	P	All mutations	P	2.0	>1
414	V	Y	All mutations	Y	2.272784412319296	>1
414	V	H	All mutations	H	2.272784412319296	>1
414	V	S	All mutations	S	2.0	>1
414	V	I	All mutations	I	1.1678189817724702	>1
414	V	M	All mutations	M	1.8321810182275298	>1
414	V	A	All mutations	A	1.0	1
414	V	N	All mutations	N	2.272784412319296	>1
414	V	L	All mutations	L	1.0	1
414	V	C	All mutations	C	2.272784412319296	>1
414	V	K	All mutations	K	2.727215587680704	>1
414	V	F	All mutations	F	1.272784412319296	>1
414	V	W	All mutations	W	2.83218101822753	>1
414	V	G	All mutations	G	1.0	1
414	V	D	All mutations	D	1.272784412319296	>1
414	V	R	All mutations	R	2.0	>1
414	V	V	All mutations	V	0.0	0
415	R	G	All mutations	G	1.0	1
415	R	N	All mutations	N	2.782526712759271	>1
415	R	A	All mutations	A	2.0	>1
415	R	I	All mutations	I	1.8126964173475801	>1
415	R	C	All mutations	C	1.9993714644877436	>1
415	R	H	All mutations	H	2.2162162162162162	>1
415	R	R	All mutations	R	0.0	0
415	R	S	All mutations	S	1.782526712759271	>1
415	R	D	All mutations	D	2.9993714644877434	>1
415	R	Q	All mutations	Q	1.217473287240729	>1
415	R	Y	All mutations	Y	2.9993714644877434	>1
415	R	V	All mutations	V	2.0	>1
415	R	K	All mutations	K	1.7837837837837838	>1
415	R	P	All mutations	P	1.2168447517284726	>1
415	R	W	All mutations	W	1.9704588309239472	>1
415	R	F	All mutations	F	2.9993714644877434	>1
415	R	T	All mutations	T	1.7831552482715274	>1
415	R	M	All mutations	M	2.7536140791954744	>1
415	R	E	All mutations	E	2.0006285355122566	>1
415	R	L	All mutations	L	1.2168447517284726	>1
416	G	E	All mutations	E	1.9792583280955374	>1
416	G	Y	All mutations	Y	2.0207416719044624	>1
416	G	S	All mutations	S	1.0207416719044626	1
416	G	I	All mutations	I	2.0125707102451287	>1
416	G	N	All mutations	N	2.0207416719044624	>1
416	G	G	All mutations	G	0.0	0
416	G	L	All mutations	L	2.0	>1
416	G	D	All mutations	D	1.0207416719044626	1
416	G	F	All mutations	F	2.0207416719044624	>1
416	G	W	All mutations	W	1.987429289754871	>1
416	G	T	All mutations	T	2.0	>1
416	G	H	All mutations	H	2.0207416719044624	>1
416	G	R	All mutations	R	1.0	1
416	G	V	All mutations	V	1.0	1
416	G	K	All mutations	K	2.9792583280955376	>1
416	G	M	All mutations	M	2.9874292897548713	>1
416	G	A	All mutations	A	1.0	1
416	G	C	All mutations	C	1.0207416719044626	1
416	G	P	All mutations	P	2.0	>1
416	G	Q	All mutations	Q	2.9792583280955376	>1
417	D	H	All mutations	H	1.0	1
417	D	A	All mutations	A	1.0006285355122564	1
417	D	L	All mutations	L	2.0	>1
417	D	S	All mutations	S	1.9993714644877436	>1
417	D	Q	All mutations	Q	2.0	>1
417	D	I	All mutations	I	1.9993714644877436	>1
417	D	P	All mutations	P	2.0	>1
417	D	T	All mutations	T	1.9993714644877436	>1
417	D	W	All mutations	W	3.0	>1
417	D	N	All mutations	N	0.9993714644877436	1
417	D	K	All mutations	K	1.9993714644877436	>1
417	D	G	All mutations	G	1.0006285355122564	1
417	D	M	All mutations	M	2.9993714644877434	>1
417	D	E	All mutations	E	1.0006285355122564	1
417	D	V	All mutations	V	1.0006285355122564	1
417	D	D	All mutations	D	0.0006285355122564425	1
417	D	F	All mutations	F	2.0	>1
417	D	R	All mutations	R	2.0	>1
417	D	Y	All mutations	Y	1.0	1
417	D	C	All mutations	C	2.0	>1
418	L	L	All mutations	L	0.0	0
418	L	F	All mutations	F	1.6555625392834694	>1
418	L	D	All mutations	D	3.0	>1
418	L	Q	All mutations	Q	1.3444374607165306	>1
418	L	P	All mutations	P	1.3444374607165306	>1
418	L	T	All mutations	T	2.0	>1
418	L	C	All mutations	C	2.6555625392834696	>1
418	L	W	All mutations	W	1.8548082966687618	>1
418	L	N	All mutations	N	3.0	>1
418	L	K	All mutations	K	2.0	>1
418	L	G	All mutations	G	2.0	>1
418	L	Y	All mutations	Y	2.6555625392834696	>1
418	L	M	All mutations	M	1.1992457573852924	>1
418	L	E	All mutations	E	2.0	>1
418	L	S	All mutations	S	1.6555625392834694	>1
418	L	I	All mutations	I	1.8007542426147076	>1
418	L	H	All mutations	H	2.3444374607165304	>1
418	L	V	All mutations	V	1.0	1
418	L	R	All mutations	R	1.3444374607165306	>1
418	L	A	All mutations	A	2.0	>1
419	N	S	All mutations	S	1.0	1
419	N	C	All mutations	C	2.0	>1
419	N	R	All mutations	R	2.0	>1
419	N	P	All mutations	P	2.0	>1
419	N	T	All mutations	T	1.0	1
419	N	F	All mutations	F	2.0	>1
419	N	W	All mutations	W	3.0	>1
419	N	I	All mutations	I	1.0	1
419	N	G	All mutations	G	2.0	>1
419	N	Y	All mutations	Y	1.0	1
419	N	D	All mutations	D	1.0	1
419	N	E	All mutations	E	2.0	>1
419	N	Q	All mutations	Q	2.0	>1
419	N	V	All mutations	V	2.0	>1
419	N	K	All mutations	K	1.0	1
419	N	L	All mutations	L	2.0	>1
419	N	M	All mutations	M	2.0	>1
419	N	A	All mutations	A	2.0	>1
419	N	H	All mutations	H	1.0	1
419	N	N	All mutations	N	0.0	0
420	F	N	All mutations	N	2.0	>1
420	F	S	All mutations	S	1.0	1
420	F	Y	All mutations	Y	1.0	1
420	F	F	All mutations	F	0.0	0
420	F	V	All mutations	V	1.0	1
420	F	M	All mutations	M	2.0	>1
420	F	H	All mutations	H	2.0	>1
420	F	G	All mutations	G	2.0	>1
420	F	W	All mutations	W	2.0	>1
420	F	I	All mutations	I	1.0	1
420	F	T	All mutations	T	2.0	>1
420	F	P	All mutations	P	2.0	>1
420	F	L	All mutations	L	1.0	1
420	F	C	All mutations	C	1.0	1
420	F	K	All mutations	K	3.0	>1
420	F	E	All mutations	E	3.0	>1
420	F	A	All mutations	A	2.0	>1
420	F	R	All mutations	R	2.0	>1
420	F	Q	All mutations	Q	3.0	>1
420	F	D	All mutations	D	2.0	>1
421	V	K	All mutations	K	2.707730986800754	>1
421	V	F	All mutations	F	1.2922690131992458	>1
421	V	V	All mutations	V	0.0006285355122564425	1
421	V	C	All mutations	C	2.292269013199246	>1
421	V	L	All mutations	L	0.9993714644877436	1
421	V	W	All mutations	W	2.8164676304211187	>1
421	V	D	All mutations	D	1.2928975487115022	>1
421	V	A	All mutations	A	1.0006285355122564	1
421	V	G	All mutations	G	1.0006285355122564	1
421	V	R	All mutations	R	1.9993714644877436	>1
421	V	Q	All mutations	Q	2.7071024512884976	>1
421	V	S	All mutations	S	2.0	>1
421	V	E	All mutations	E	1.7083595223130106	>1
421	V	I	All mutations	I	1.1835323695788813	>1
421	V	Y	All mutations	Y	2.292269013199246	>1
421	V	P	All mutations	P	1.9993714644877436	>1
421	V	T	All mutations	T	2.0	>1
421	V	N	All mutations	N	2.292269013199246	>1
421	V	H	All mutations	H	2.291640477686989	>1
421	V	M	All mutations	M	1.8164676304211187	>1
422	N	C	All mutations	C	2.0	>1
422	N	V	All mutations	V	2.0	>1
422	N	S	All mutations	S	1.0	1
422	N	K	All mutations	K	1.0006285355122564	1
422	N	E	All mutations	E	2.0006285355122566	>1
422	N	Q	All mutations	Q	2.0006285355122566	>1
422	N	H	All mutations	H	1.0006285355122564	1
422	N	R	All mutations	R	2.0	>1
422	N	P	All mutations	P	1.9993714644877436	>1
422	N	D	All mutations	D	1.0006285355122564	1
422	N	I	All mutations	I	1.0	1
422	N	A	All mutations	A	1.9993714644877436	>1
422	N	L	All mutations	L	2.0	>1
422	N	M	All mutations	M	2.0	>1
422	N	G	All mutations	G	2.0	>1
422	N	Y	All mutations	Y	1.0006285355122564	1
422	N	F	All mutations	F	2.0	>1
422	N	W	All mutations	W	3.0	>1
422	N	N	All mutations	N	0.0006285355122564425	1
422	N	T	All mutations	T	0.9993714644877436	1
423	R	D	All mutations	D	3.0	>1
423	R	R	All mutations	R	0.0	0
423	R	C	All mutations	C	2.0	>1
423	R	H	All mutations	H	3.0	>1
423	R	G	All mutations	G	1.0	1
423	R	V	All mutations	V	2.0	>1
423	R	P	All mutations	P	2.0	>1
423	R	S	All mutations	S	1.0	1
423	R	E	All mutations	E	2.0	>1
423	R	W	All mutations	W	1.6027655562539282	>1
423	R	K	All mutations	K	1.0	1
423	R	M	All mutations	M	1.6027655562539282	>1
423	R	F	All mutations	F	3.0	>1
423	R	Q	All mutations	Q	2.0	>1
423	R	Y	All mutations	Y	3.0	>1
423	R	L	All mutations	L	2.0	>1
423	R	A	All mutations	A	2.0	>1
423	R	T	All mutations	T	1.0	1
423	R	N	All mutations	N	2.0	>1
423	R	I	All mutations	I	1.3972344437460718	>1
424	A	M	All mutations	M	2.468887492143306	>1
424	A	E	All mutations	E	1.055311125078567	1
424	A	C	All mutations	C	2.9446888749214333	>1
424	A	K	All mutations	K	2.0553111250785667	>1
424	A	H	All mutations	H	2.9446888749214333	>1
424	A	P	All mutations	P	1.0	1
424	A	S	All mutations	S	1.0	1
424	A	Q	All mutations	Q	2.0553111250785667	>1
424	A	D	All mutations	D	1.944688874921433	>1
424	A	T	All mutations	T	1.0	1
424	A	L	All mutations	L	2.0	>1
424	A	R	All mutations	R	2.0	>1
424	A	N	All mutations	N	2.9446888749214333	>1
424	A	A	All mutations	A	0.0	0
424	A	G	All mutations	G	1.0	1
424	A	F	All mutations	F	2.9446888749214333	>1
424	A	W	All mutations	W	2.468887492143306	>1
424	A	Y	All mutations	Y	2.9446888749214333	>1
424	A	I	All mutations	I	2.531112507856694	>1
424	A	V	All mutations	V	1.0	1
425	N	G	All mutations	G	2.0	>1
425	N	R	All mutations	R	2.0	>1
425	N	W	All mutations	W	3.0	>1
425	N	M	All mutations	M	2.0	>1
425	N	P	All mutations	P	2.0	>1
425	N	V	All mutations	V	2.0	>1
425	N	H	All mutations	H	1.0	1
425	N	N	All mutations	N	0.0	0
425	N	A	All mutations	A	2.0	>1
425	N	L	All mutations	L	2.0	>1
425	N	C	All mutations	C	2.0	>1
425	N	K	All mutations	K	1.0	1
425	N	S	All mutations	S	1.0	1
425	N	F	All mutations	F	2.0	>1
425	N	Y	All mutations	Y	1.0	1
425	N	T	All mutations	T	1.0	1
425	N	I	All mutations	I	1.0	1
425	N	Q	All mutations	Q	2.0	>1
425	N	E	All mutations	E	2.0	>1
425	N	D	All mutations	D	1.0	1
426	Q	Y	All mutations	Y	2.0006285355122566	>1
426	Q	A	All mutations	A	2.0	>1
426	Q	E	All mutations	E	1.0006285355122564	1
426	Q	H	All mutations	H	1.0006285355122564	1
426	Q	L	All mutations	L	0.9993714644877436	1
426	Q	Q	All mutations	Q	0.0006285355122564425	1
426	Q	G	All mutations	G	2.0	>1
426	Q	K	All mutations	K	1.0006285355122564	1
426	Q	R	All mutations	R	1.0	1
426	Q	I	All mutations	I	2.688874921433061	>1
426	Q	M	All mutations	M	2.309868007542426	>1
426	Q	V	All mutations	V	1.9993714644877436	>1
426	Q	N	All mutations	N	2.0006285355122566	>1
426	Q	W	All mutations	W	2.3104965430546827	>1
426	Q	F	All mutations	F	2.9993714644877434	>1
426	Q	S	All mutations	S	2.0	>1
426	Q	T	All mutations	T	2.0	>1
426	Q	P	All mutations	P	1.0	1
426	Q	C	All mutations	C	3.0	>1
426	Q	D	All mutations	D	2.0006285355122566	>1
427	R	E	All mutations	E	2.001257071024513	>1
427	R	D	All mutations	D	2.998742928975487	>1
427	R	K	All mutations	K	1.7611565053425517	>1
427	R	G	All mutations	G	1.0	1
427	R	P	All mutations	P	1.240100565681961	>1
427	R	I	All mutations	I	2.52294154619736	>1
427	R	N	All mutations	N	2.758642363293526	>1
427	R	Q	All mutations	Q	1.2413576367064738	>1
427	R	Y	All mutations	Y	2.998742928975487	>1
427	R	V	All mutations	V	2.0	>1
427	R	L	All mutations	L	1.240100565681961	>1
427	R	H	All mutations	H	2.238843494657448	>1
427	R	C	All mutations	C	1.9987429289754872	>1
427	R	M	All mutations	M	1.9968573224387178	>1
427	R	S	All mutations	S	1.7586423632935262	>1
427	R	W	All mutations	W	1.2369578881206789	>1
427	R	A	All mutations	A	2.0	>1
427	R	T	All mutations	T	1.759899434318039	>1
427	R	F	All mutations	F	2.998742928975487	>1
427	R	R	All mutations	R	0.0	0
428	L	T	All mutations	T	1.9993714644877436	>1
428	L	D	All mutations	D	2.989943431803897	>1
428	L	W	All mutations	W	2.1697045883092394	>1
428	L	M	All mutations	M	1.4494028912633563	>1
428	L	R	All mutations	R	1.2809553739786297	>1
428	L	L	All mutations	L	0.0006285355122564425	1
428	L	V	All mutations	V	1.0	1
428	L	I	All mutations	I	1.5493400377121307	>1
428	L	S	All mutations	S	1.7190446260213703	>1
428	L	Y	All mutations	Y	2.7096165933375236	>1
428	L	N	All mutations	N	2.9893148962916403	>1
428	L	A	All mutations	A	2.0	>1
428	L	H	All mutations	H	2.270898805782527	>1
428	L	P	All mutations	P	1.2809553739786297	>1
428	L	F	All mutations	F	1.7096165933375236	>1
428	L	E	All mutations	E	2.010056568196103	>1
428	L	G	All mutations	G	2.0	>1
428	L	K	All mutations	K	2.0094280326838465	>1
428	L	C	All mutations	C	2.7096165933375236	>1
428	L	Q	All mutations	Q	1.2910119421747328	>1
429	N	M	All mutations	M	2.0006285355122566	>1
429	N	Y	All mutations	Y	1.0018856065367694	1
429	N	Q	All mutations	Q	2.0025141420490256	>1
429	N	D	All mutations	D	1.0025141420490258	1
429	N	S	All mutations	S	0.9981143934632307	1
429	N	P	All mutations	P	1.9993714644877436	>1
429	N	L	All mutations	L	2.0	>1
429	N	N	All mutations	N	0.0031426775612822125	1
429	N	H	All mutations	H	1.0025141420490258	1
429	N	G	All mutations	G	1.9981143934632306	>1
429	N	C	All mutations	C	1.9974858579509742	>1
429	N	R	All mutations	R	1.9981143934632306	>1
429	N	W	All mutations	W	2.9974858579509744	>1
429	N	F	All mutations	F	1.9993714644877436	>1
429	N	I	All mutations	I	1.0006285355122564	1
429	N	V	All mutations	V	2.0	>1
429	N	K	All mutations	K	1.0031426775612822	1
429	N	A	All mutations	A	1.9993714644877436	>1
429	N	T	All mutations	T	1.0	1
429	N	E	All mutations	E	2.0025141420490256	>1
430	P	Q	All mutations	Q	1.5311125078566938	>1
430	P	T	All mutations	T	1.0	1
430	P	C	All mutations	C	2.468887492143306	>1
430	P	K	All mutations	K	2.5292269013199244	>1
430	P	Y	All mutations	Y	2.468887492143306	>1
430	P	H	All mutations	H	1.4726587052168447	>1
430	P	M	All mutations	M	2.9836580766813325	>1
430	P	W	All mutations	W	2.981772470144563	>1
430	P	A	All mutations	A	1.0	1
430	P	S	All mutations	S	0.9981143934632307	1
430	P	N	All mutations	N	2.4707730986800756	>1
430	P	D	All mutations	D	2.4707730986800756	>1
430	P	E	All mutations	E	2.5292269013199244	>1
430	P	L	All mutations	L	1.0018856065367694	1
430	P	R	All mutations	R	1.0018856065367694	1
430	P	P	All mutations	P	0.0018856065367693275	1
430	P	I	All mutations	I	2.0163419233186675	>1
430	P	G	All mutations	G	2.0	>1
430	P	F	All mutations	F	2.468887492143306	>1
430	P	V	All mutations	V	2.0	>1
431	M	Q	All mutations	Q	2.0	>1
431	M	G	All mutations	G	2.0	>1
431	M	D	All mutations	D	3.0	>1
431	M	W	All mutations	W	1.9987429289754872	>1
431	M	S	All mutations	S	1.9987429289754872	>1
431	M	N	All mutations	N	2.001257071024513	>1
431	M	A	All mutations	A	2.0	>1
431	M	T	All mutations	T	1.0012570710245128	1
431	M	F	All mutations	F	1.9987429289754872	>1
431	M	H	All mutations	H	3.0	>1
431	M	P	All mutations	P	2.0	>1
431	M	L	All mutations	L	0.9987429289754871	1
431	M	C	All mutations	C	2.998742928975487	>1
431	M	Y	All mutations	Y	2.998742928975487	>1
431	M	R	All mutations	R	1.0012570710245128	1
431	M	K	All mutations	K	1.0012570710245128	1
431	M	I	All mutations	I	1.0012570710245128	1
431	M	V	All mutations	V	1.0	1
431	M	M	All mutations	M	0.001257071024512885	1
431	M	E	All mutations	E	2.0	>1
432	H	P	All mutations	P	1.0006285355122564	1
432	H	T	All mutations	T	2.0	>1
432	H	Y	All mutations	Y	0.9993714644877436	1
432	H	L	All mutations	L	1.0006285355122564	1
432	H	S	All mutations	S	1.9993714644877436	>1
432	H	D	All mutations	D	1.0	1
432	H	G	All mutations	G	2.0	>1
432	H	C	All mutations	C	1.9993714644877436	>1
432	H	W	All mutations	W	2.9993714644877434	>1
432	H	N	All mutations	N	1.0	1
432	H	A	All mutations	A	2.0	>1
432	H	M	All mutations	M	3.0	>1
432	H	F	All mutations	F	1.9993714644877436	>1
432	H	H	All mutations	H	0.0006285355122564425	1
432	H	K	All mutations	K	2.0	>1
432	H	R	All mutations	R	1.0006285355122564	1
432	H	I	All mutations	I	2.0	>1
432	H	E	All mutations	E	2.0	>1
432	H	Q	All mutations	Q	1.0006285355122564	1
432	H	V	All mutations	V	2.0	>1
433	Q	R	All mutations	R	1.0	1
433	Q	T	All mutations	T	2.0	>1
433	Q	E	All mutations	E	1.0	1
433	Q	K	All mutations	K	1.0	1
433	Q	Y	All mutations	Y	2.0	>1
433	Q	S	All mutations	S	2.0	>1
433	Q	N	All mutations	N	2.0	>1
433	Q	H	All mutations	H	1.0	1
433	Q	C	All mutations	C	3.0	>1
433	Q	L	All mutations	L	1.0	1
433	Q	G	All mutations	G	2.0	>1
433	Q	W	All mutations	W	2.7774984286612194	>1
433	Q	I	All mutations	I	2.2225015713387806	>1
433	Q	A	All mutations	A	2.0	>1
433	Q	M	All mutations	M	2.7774984286612194	>1
433	Q	V	All mutations	V	2.0	>1
433	Q	D	All mutations	D	2.0	>1
433	Q	F	All mutations	F	3.0	>1
433	Q	Q	All mutations	Q	0.0	0
433	Q	P	All mutations	P	1.0	1
434	L	K	All mutations	K	2.9660590823381523	>1
434	L	Q	All mutations	Q	1.9748585795097422	>1
434	L	W	All mutations	W	2.974230043997486	>1
434	L	E	All mutations	E	2.9660590823381523	>1
434	L	N	All mutations	N	2.0339409176618477	>1
434	L	V	All mutations	V	1.0	1
434	L	A	All mutations	A	2.0	>1
434	L	I	All mutations	I	1.0169704588309239	1
434	L	G	All mutations	G	2.0	>1
434	L	L	All mutations	L	0.0018856065367693275	1
434	L	R	All mutations	R	1.0087994971715901	1
434	L	M	All mutations	M	1.9830295411690761	>1
434	L	P	All mutations	P	1.0087994971715901	1
434	L	Y	All mutations	Y	2.025141420490258	>1
434	L	S	All mutations	S	1.9912005028284099	>1
434	L	D	All mutations	D	2.0339409176618477	>1
434	L	F	All mutations	F	1.0251414204902578	1
434	L	H	All mutations	H	1.042740414833438	1
434	L	C	All mutations	C	2.025141420490258	>1
434	L	T	All mutations	T	2.0	>1
435	L	H	All mutations	H	2.4456316781898177	>1
435	L	K	All mutations	K	2.0018856065367694	>1
435	L	E	All mutations	E	2.0018856065367694	>1
435	L	Q	All mutations	Q	1.4494028912633563	>1
435	L	Y	All mutations	Y	2.5505971087366435	>1
435	L	I	All mutations	I	1.966059082338152	>1
435	L	M	All mutations	M	1.033940917661848	1
435	L	V	All mutations	V	1.0	1
435	L	L	All mutations	L	0.0	0
435	L	A	All mutations	A	2.0	>1
435	L	P	All mutations	P	1.4475172847265871	>1
435	L	F	All mutations	F	1.5505971087366437	>1
435	L	G	All mutations	G	2.0	>1
435	L	W	All mutations	W	1.5864236329352608	>1
435	L	S	All mutations	S	1.5524827152734129	>1
435	L	D	All mutations	D	2.9981143934632306	>1
435	L	R	All mutations	R	1.4475172847265871	>1
435	L	C	All mutations	C	2.5505971087366435	>1
435	L	N	All mutations	N	2.9981143934632306	>1
435	L	T	All mutations	T	2.0	>1
436	R	G	All mutations	G	1.0	1
436	R	C	All mutations	C	2.0	>1
436	R	V	All mutations	V	2.0	>1
436	R	H	All mutations	H	2.9893148962916403	>1
436	R	F	All mutations	F	3.0	>1
436	R	Q	All mutations	Q	1.9893148962916405	>1
436	R	P	All mutations	P	1.9893148962916405	>1
436	R	S	All mutations	S	1.0106851037083595	1
436	R	I	All mutations	I	1.403519798868636	>1
436	R	A	All mutations	A	2.0	>1
436	R	D	All mutations	D	3.0	>1
436	R	T	All mutations	T	1.0106851037083595	1
436	R	R	All mutations	R	0.0	0
436	R	N	All mutations	N	2.0106851037083597	>1
436	R	K	All mutations	K	1.0106851037083595	1
436	R	L	All mutations	L	1.9893148962916405	>1
436	R	E	All mutations	E	2.0	>1
436	R	Y	All mutations	Y	3.0	>1
436	R	M	All mutations	M	1.617850408548083	>1
436	R	W	All mutations	W	1.6071653048397234	>1
437	H	N	All mutations	N	1.0	1
437	H	S	All mutations	S	2.0	>1
437	H	C	All mutations	C	2.0	>1
437	H	Q	All mutations	Q	1.0	1
437	H	L	All mutations	L	1.0	1
437	H	A	All mutations	A	2.0	>1
437	H	G	All mutations	G	2.0	>1
437	H	I	All mutations	I	2.0	>1
437	H	E	All mutations	E	2.0	>1
437	H	P	All mutations	P	1.0	1
437	H	Y	All mutations	Y	1.0	1
437	H	F	All mutations	F	2.0	>1
437	H	V	All mutations	V	2.0	>1
437	H	D	All mutations	D	1.0	1
437	H	M	All mutations	M	3.0	>1
437	H	W	All mutations	W	3.0	>1
437	H	H	All mutations	H	0.0	0
437	H	K	All mutations	K	2.0	>1
437	H	T	All mutations	T	2.0	>1
437	H	R	All mutations	R	1.0	1
438	F	F	All mutations	F	0.0	0
438	F	K	All mutations	K	3.0	>1
438	F	H	All mutations	H	2.0	>1
438	F	N	All mutations	N	2.0	>1
438	F	S	All mutations	S	1.0	1
438	F	R	All mutations	R	2.0	>1
438	F	G	All mutations	G	2.0	>1
438	F	Y	All mutations	Y	1.0	1
438	F	Q	All mutations	Q	3.0	>1
438	F	M	All mutations	M	2.0	>1
438	F	E	All mutations	E	3.0	>1
438	F	I	All mutations	I	1.0	1
438	F	D	All mutations	D	2.0	>1
438	F	A	All mutations	A	2.0	>1
438	F	L	All mutations	L	1.0	1
438	F	P	All mutations	P	2.0	>1
438	F	T	All mutations	T	2.0	>1
438	F	W	All mutations	W	2.0	>1
438	F	V	All mutations	V	1.0	1
438	F	C	All mutations	C	1.0	1
439	Q	W	All mutations	W	2.914519170333124	>1
439	Q	K	All mutations	K	1.0006285355122564	1
439	Q	N	All mutations	N	2.0006285355122566	>1
439	Q	R	All mutations	R	0.9993714644877436	1
439	Q	M	All mutations	M	2.91514770584538	>1
439	Q	P	All mutations	P	1.0	1
439	Q	Q	All mutations	Q	0.0006285355122564425	1
439	Q	H	All mutations	H	1.0006285355122564	1
439	Q	C	All mutations	C	2.9993714644877434	>1
439	Q	G	All mutations	G	1.9993714644877436	>1
439	Q	E	All mutations	E	1.0006285355122564	1
439	Q	V	All mutations	V	2.0	>1
439	Q	S	All mutations	S	2.0	>1
439	Q	I	All mutations	I	2.08485229415462	>1
439	Q	L	All mutations	L	1.0	1
439	Q	T	All mutations	T	2.0	>1
439	Q	F	All mutations	F	3.0	>1
439	Q	Y	All mutations	Y	2.0006285355122566	>1
439	Q	A	All mutations	A	2.0	>1
439	Q	D	All mutations	D	2.0006285355122566	>1
440	K	K	All mutations	K	0.014456316781898177	1
440	K	A	All mutations	A	2.0	>1
440	K	W	All mutations	W	2.143306096794469	>1
440	K	M	All mutations	M	1.157762413576367	>1
440	K	I	All mutations	I	1.842237586423633	>1
440	K	E	All mutations	E	1.014456316781898	1
440	K	D	All mutations	D	2.014456316781898	>1
440	K	Q	All mutations	Q	1.014456316781898	1
440	K	P	All mutations	P	2.0	>1
440	K	F	All mutations	F	3.0	>1
440	K	L	All mutations	L	2.0	>1
440	K	C	All mutations	C	2.985543683218102	>1
440	K	V	All mutations	V	2.0	>1
440	K	R	All mutations	R	0.9855436832181018	1
440	K	G	All mutations	G	1.985543683218102	>1
440	K	H	All mutations	H	2.014456316781898	>1
440	K	N	All mutations	N	1.014456316781898	1
440	K	S	All mutations	S	1.985543683218102	>1
440	K	T	All mutations	T	1.0	1
440	K	Y	All mutations	Y	2.014456316781898	>1
441	D	I	All mutations	I	1.9327467001885608	>1
441	D	A	All mutations	A	1.0672532998114392	1
441	D	Q	All mutations	Q	2.001257071024513	>1
441	D	T	All mutations	T	1.9327467001885608	>1
441	D	E	All mutations	E	1.0685103708359522	1
441	D	C	All mutations	C	1.9987429289754872	>1
441	D	R	All mutations	R	1.9987429289754872	>1
441	D	P	All mutations	P	2.0	>1
441	D	G	All mutations	G	1.0659962287869265	1
441	D	M	All mutations	M	2.9327467001885608	>1
441	D	H	All mutations	H	1.0012570710245128	1
441	D	V	All mutations	V	1.0672532998114392	1
441	D	S	All mutations	S	1.9314896291640478	>1
441	D	D	All mutations	D	0.06851037083595223	1
441	D	K	All mutations	K	1.9340037712130735	>1
441	D	Y	All mutations	Y	1.0012570710245128	1
441	D	N	All mutations	N	0.9340037712130735	1
441	D	L	All mutations	L	2.0	>1
441	D	W	All mutations	W	2.998742928975487	>1
441	D	F	All mutations	F	2.0	>1
442	A	E	All mutations	E	1.0999371464487744	1
442	A	D	All mutations	D	1.9038340666247644	>1
442	A	K	All mutations	K	2.098051539912005	>1
442	A	A	All mutations	A	0.0018856065367693275	1
442	A	V	All mutations	V	1.0018856065367694	1
442	A	Y	All mutations	Y	2.900062853551226	>1
442	A	F	All mutations	F	2.900062853551226	>1
442	A	W	All mutations	W	2.974230043997486	>1
442	A	P	All mutations	P	1.0	1
442	A	L	All mutations	L	2.0	>1
442	A	S	All mutations	S	0.9981143934632307	1
442	A	G	All mutations	G	1.0018856065367694	1
442	A	Q	All mutations	Q	2.098051539912005	>1
442	A	M	All mutations	M	2.976115650534255	>1
442	A	H	All mutations	H	2.901948460087995	>1
442	A	C	All mutations	C	2.900062853551226	>1
442	A	T	All mutations	T	1.0	1
442	A	I	All mutations	I	2.023884349465745	>1
442	A	R	All mutations	R	2.0	>1
442	A	N	All mutations	N	2.901948460087995	>1
443	K	W	All mutations	W	2.597737272155877	>1
443	K	K	All mutations	K	0.00502828409805154	1
443	K	V	All mutations	V	2.0	>1
443	K	C	All mutations	C	2.9949717159019484	>1
443	K	M	All mutations	M	1.6027655562539282	>1
443	K	N	All mutations	N	1.0050282840980516	1
443	K	P	All mutations	P	2.0	>1
443	K	Y	All mutations	Y	2.0050282840980516	>1
443	K	G	All mutations	G	1.9949717159019484	>1
443	K	S	All mutations	S	1.9949717159019484	>1
443	K	R	All mutations	R	0.9949717159019484	1
443	K	A	All mutations	A	2.0	>1
443	K	E	All mutations	E	1.0050282840980516	1
443	K	H	All mutations	H	2.0050282840980516	>1
443	K	Q	All mutations	Q	1.0050282840980516	1
443	K	L	All mutations	L	2.0	>1
443	K	F	All mutations	F	3.0	>1
443	K	I	All mutations	I	1.3972344437460718	>1
443	K	T	All mutations	T	1.0	1
443	K	D	All mutations	D	2.0050282840980516	>1
444	V	Q	All mutations	Q	2.096165933375236	>1
444	V	M	All mutations	M	1.2099308610936519	>1
444	V	L	All mutations	L	1.0	1
444	V	T	All mutations	T	1.9924575738529227	>1
444	V	W	All mutations	W	2.217473287240729	>1
444	V	G	All mutations	G	1.0075424261470773	1
444	V	F	All mutations	F	1.9038340666247644	>1
444	V	P	All mutations	P	2.0	>1
444	V	H	All mutations	H	2.903834066624764	>1
444	V	N	All mutations	N	2.896291640477687	>1
444	V	R	All mutations	R	1.9962287869264614	>1
444	V	I	All mutations	I	1.7749842866121937	>1
444	V	V	All mutations	V	0.00754242614707731	1
444	V	A	All mutations	A	1.0075424261470773	1
444	V	K	All mutations	K	2.0886235072281583	>1
444	V	S	All mutations	S	1.9962287869264614	>1
444	V	D	All mutations	D	1.9113764927718415	>1
444	V	C	All mutations	C	2.903834066624764	>1
444	V	E	All mutations	E	1.103708359522313	>1
444	V	Y	All mutations	Y	2.903834066624764	>1
445	L	R	All mutations	R	1.0634820867379007	1
445	L	S	All mutations	S	1.9371464487743557	>1
445	L	C	All mutations	C	2.4783155248271527	>1
445	L	N	All mutations	N	2.541169076052797	>1
445	L	M	All mutations	M	1.6480201131363923	>1
445	L	P	All mutations	P	1.0634820867379007	1
445	L	A	All mutations	A	1.9993714644877436	>1
445	L	F	All mutations	F	1.4783155248271527	>1
445	L	V	All mutations	V	0.9993714644877436	1
445	L	Y	All mutations	Y	2.4783155248271527	>1
445	L	E	All mutations	E	2.4582023884349464	>1
445	L	W	All mutations	W	2.585166561910748	>1
445	L	H	All mutations	H	1.6046511627906976	>1
445	L	I	All mutations	I	1.3519798868636077	>1
445	L	L	All mutations	L	0.0006285355122564425	1
445	L	D	All mutations	D	2.5405405405405403	>1
445	L	Q	All mutations	Q	1.5223130106851037	>1
445	L	K	All mutations	K	2.458830923947203	>1
445	L	G	All mutations	G	1.9993714644877436	>1
445	L	T	All mutations	T	2.0	>1
446	F	V	All mutations	V	1.0	1
446	F	S	All mutations	S	1.0031426775612822	1
446	F	P	All mutations	P	1.9968573224387178	>1
446	F	H	All mutations	H	1.9968573224387178	>1
446	F	Y	All mutations	Y	1.0031426775612822	1
446	F	T	All mutations	T	2.0	>1
446	F	Q	All mutations	Q	2.996857322438718	>1
446	F	E	All mutations	E	3.0	>1
446	F	W	All mutations	W	2.003142677561282	>1
446	F	C	All mutations	C	1.0031426775612822	1
446	F	F	All mutations	F	0.0031426775612822125	1
446	F	G	All mutations	G	2.0	>1
446	F	K	All mutations	K	3.0	>1
446	F	I	All mutations	I	1.0	1
446	F	L	All mutations	L	0.9968573224387178	1
446	F	R	All mutations	R	1.9968573224387178	>1
446	F	A	All mutations	A	2.0	>1
446	F	M	All mutations	M	2.0	>1
446	F	N	All mutations	N	2.0	>1
446	F	D	All mutations	D	2.0	>1
447	Q	M	All mutations	M	2.780012570710245	>1
447	Q	H	All mutations	H	0.9987429289754871	1
447	Q	W	All mutations	W	2.781269641734758	>1
447	Q	A	All mutations	A	2.0	>1
447	Q	S	All mutations	S	2.0	>1
447	Q	T	All mutations	T	1.9993714644877436	>1
447	Q	V	All mutations	V	1.9993714644877436	>1
447	Q	G	All mutations	G	2.0	>1
447	Q	D	All mutations	D	1.9981143934632306	>1
447	Q	F	All mutations	F	2.996857322438718	>1
447	Q	Y	All mutations	Y	1.9981143934632306	>1
447	Q	C	All mutations	C	2.9974858579509744	>1
447	Q	K	All mutations	K	1.0025141420490258	1
447	Q	E	All mutations	E	1.0031426775612822	1
447	Q	I	All mutations	I	2.217473287240729	>1
447	Q	P	All mutations	P	1.0006285355122564	1
447	Q	R	All mutations	R	1.0	1
447	Q	N	All mutations	N	1.9974858579509742	>1
447	Q	Q	All mutations	Q	0.003771213073538655	1
447	Q	L	All mutations	L	1.0	1
448	N	K	All mutations	K	1.0106851037083595	1
448	N	G	All mutations	G	1.9899434318038969	>1
448	N	N	All mutations	N	0.011942174732872407	1
448	N	F	All mutations	F	2.0006285355122566	>1
448	N	H	All mutations	H	1.0119421747328725	1
448	N	L	All mutations	L	2.0	>1
448	N	Y	All mutations	Y	1.0119421747328725	1
448	N	A	All mutations	A	1.9987429289754872	>1
448	N	P	All mutations	P	1.9987429289754872	>1
448	N	R	All mutations	R	1.9893148962916405	>1
448	N	D	All mutations	D	1.0119421747328725	1
448	N	I	All mutations	I	1.0	1
448	N	M	All mutations	M	2.0	>1
448	N	C	All mutations	C	1.9905719673161533	>1
448	N	Q	All mutations	Q	2.0106851037083597	>1
448	N	S	All mutations	S	0.9905719673161534	1
448	N	W	All mutations	W	2.989943431803897	>1
448	N	T	All mutations	T	0.9987429289754871	1
448	N	E	All mutations	E	2.0106851037083597	>1
448	N	V	All mutations	V	2.0	>1
449	W	K	All mutations	K	2.0	>1
449	W	T	All mutations	T	2.0	>1
449	W	P	All mutations	P	2.0	>1
449	W	H	All mutations	H	3.0	>1
449	W	F	All mutations	F	2.0	>1
449	W	E	All mutations	E	2.0	>1
449	W	Y	All mutations	Y	2.0	>1
449	W	C	All mutations	C	1.0	1
449	W	G	All mutations	G	1.0	1
449	W	L	All mutations	L	1.0	1
449	W	N	All mutations	N	3.0	>1
449	W	A	All mutations	A	2.0	>1
449	W	V	All mutations	V	2.0	>1
449	W	M	All mutations	M	2.0	>1
449	W	D	All mutations	D	3.0	>1
449	W	I	All mutations	I	3.0	>1
449	W	W	All mutations	W	0.0	0
449	W	S	All mutations	S	1.0	1
449	W	Q	All mutations	Q	2.0	>1
449	W	R	All mutations	R	1.0	1
450	G	C	All mutations	C	1.9993714644877436	>1
450	G	N	All mutations	N	2.9993714644877434	>1
450	G	M	All mutations	M	2.786926461345066	>1
450	G	H	All mutations	H	2.9993714644877434	>1
450	G	Y	All mutations	Y	2.9993714644877434	>1
450	G	E	All mutations	E	1.0006285355122564	1
450	G	D	All mutations	D	1.9993714644877436	>1
450	G	P	All mutations	P	2.0	>1
450	G	L	All mutations	L	2.0	>1
450	G	Q	All mutations	Q	2.0006285355122566	>1
450	G	S	All mutations	S	1.9993714644877436	>1
450	G	K	All mutations	K	2.0006285355122566	>1
450	G	R	All mutations	R	1.0	1
450	G	W	All mutations	W	1.786926461345066	>1
450	G	V	All mutations	V	1.0	1
450	G	A	All mutations	A	1.0	1
450	G	G	All mutations	G	0.0	0
450	G	T	All mutations	T	2.0	>1
450	G	F	All mutations	F	2.9993714644877434	>1
450	G	I	All mutations	I	2.213073538654934	>1
451	I	S	All mutations	S	1.169076052796983	>1
451	I	A	All mutations	A	1.895034569453174	>1
451	I	T	All mutations	T	1.153362664990572	>1
451	I	H	All mutations	H	1.9258328095537398	>1
451	I	D	All mutations	D	1.9239472030169704	>1
451	I	C	All mutations	C	2.005656819610308	>1
451	I	N	All mutations	N	1.1822752985543683	>1
451	I	K	All mutations	K	2.163419233186675	>1
451	I	M	All mutations	M	1.186046511627907	>1
451	I	E	All mutations	E	2.9050911376492774	>1
451	I	Y	All mutations	Y	2.005656819610308	>1
451	I	W	All mutations	W	2.989943431803897	>1
451	I	F	All mutations	F	1.0251414204902578	1
451	I	G	All mutations	G	1.914519170333124	>1
451	I	L	All mutations	L	0.9321181646763043	1
451	I	Q	All mutations	Q	2.9069767441860463	>1
451	I	R	All mutations	R	1.916404776869893	>1
451	I	P	All mutations	P	1.8969201759899434	>1
451	I	V	All mutations	V	0.9340037712130735	1
451	I	I	All mutations	I	0.19861722187303582	1
452	E	N	All mutations	N	2.0006285355122566	>1
452	E	W	All mutations	W	2.83218101822753	>1
452	E	H	All mutations	H	2.0006285355122566	>1
452	E	P	All mutations	P	2.0	>1
452	E	I	All mutations	I	2.167190446260214	>1
452	E	D	All mutations	D	1.0006285355122564	1
452	E	E	All mutations	E	0.0006285355122564425	1
452	E	L	All mutations	L	2.0	>1
452	E	T	All mutations	T	2.0	>1
452	E	Y	All mutations	Y	2.0006285355122566	>1
452	E	Q	All mutations	Q	1.0006285355122564	1
452	E	C	All mutations	C	2.9993714644877434	>1
452	E	R	All mutations	R	1.9993714644877436	>1
452	E	V	All mutations	V	1.0	1
452	E	M	All mutations	M	2.832809553739786	>1
452	E	F	All mutations	F	3.0	>1
452	E	S	All mutations	S	2.0	>1
452	E	G	All mutations	G	0.9993714644877436	1
452	E	A	All mutations	A	1.0	1
452	E	K	All mutations	K	1.0006285355122564	1
453	P	T	All mutations	T	1.0087994971715901	1
453	P	M	All mutations	M	2.9836580766813325	>1
453	P	H	All mutations	H	1.0678818353236958	1
453	P	P	All mutations	P	0.03834066624764299	1
453	P	F	All mutations	F	2.0521684475172846	>1
453	P	E	All mutations	E	2.9182903834066627	>1
453	P	W	All mutations	W	2.9836580766813325	>1
453	P	A	All mutations	A	1.015713387806411	1
453	P	R	All mutations	R	1.0207416719044626	1
453	P	Y	All mutations	Y	2.0370835952231303	>1
453	P	K	All mutations	K	2.9113764927718417	>1
453	P	I	All mutations	I	1.9962287869264614	>1
453	P	C	All mutations	C	2.053425518541798	>1
453	P	L	All mutations	L	1.0194846008799496	1
453	P	G	All mutations	G	1.9981143934632306	>1
453	P	Q	All mutations	Q	1.9409176618478945	>1
453	P	D	All mutations	D	2.045254556882464	>1
453	P	N	All mutations	N	2.038340666247643	>1
453	P	V	All mutations	V	1.9968573224387178	>1
453	P	S	All mutations	S	1.0075424261470773	1
454	I	K	All mutations	K	1.9893148962916405	>1
454	I	G	All mutations	G	1.9987429289754872	>1
454	I	D	All mutations	D	2.0106851037083597	>1
454	I	Q	All mutations	Q	2.9880578252671275	>1
454	I	W	All mutations	W	3.0	>1
454	I	R	All mutations	R	1.9880578252671275	>1
454	I	L	All mutations	L	1.0	1
454	I	E	All mutations	E	2.9868007542426147	>1
454	I	I	All mutations	I	0.001257071024512885	1
454	I	P	All mutations	P	2.0	>1
454	I	M	All mutations	M	1.0012570710245128	1
454	I	Y	All mutations	Y	2.0119421747328725	>1
454	I	F	All mutations	F	1.0119421747328725	1
454	I	V	All mutations	V	0.9987429289754871	1
454	I	S	All mutations	S	1.0131992457573853	1
454	I	A	All mutations	A	1.9987429289754872	>1
454	I	H	All mutations	H	2.0119421747328725	>1
454	I	C	All mutations	C	2.0119421747328725	>1
454	I	T	All mutations	T	1.0012570710245128	1
454	I	N	All mutations	N	1.0131992457573853	1
455	D	V	All mutations	V	1.0	1
455	D	H	All mutations	H	1.0	1
455	D	Q	All mutations	Q	2.0	>1
455	D	R	All mutations	R	2.0	>1
455	D	S	All mutations	S	2.0	>1
455	D	D	All mutations	D	0.0	0
455	D	W	All mutations	W	3.0	>1
455	D	N	All mutations	N	1.0	1
455	D	P	All mutations	P	2.0	>1
455	D	T	All mutations	T	2.0	>1
455	D	I	All mutations	I	2.0	>1
455	D	L	All mutations	L	2.0	>1
455	D	E	All mutations	E	1.0	1
455	D	G	All mutations	G	1.0	1
455	D	M	All mutations	M	3.0	>1
455	D	Y	All mutations	Y	1.0	1
455	D	F	All mutations	F	2.0	>1
455	D	A	All mutations	A	1.0	1
455	D	C	All mutations	C	2.0	>1
455	D	K	All mutations	K	2.0	>1
456	N	P	All mutations	P	2.0	>1
456	N	Y	All mutations	Y	1.0163419233186675	1
456	N	C	All mutations	C	1.9861722187303583	>1
456	N	V	All mutations	V	1.9987429289754872	>1
456	N	I	All mutations	I	1.0025141420490258	1
456	N	K	All mutations	K	1.0150848522941547	1
456	N	H	All mutations	H	1.0163419233186675	1
456	N	L	All mutations	L	2.0	>1
456	N	N	All mutations	N	0.01759899434318039	1
456	N	D	All mutations	D	1.0150848522941547	1
456	N	R	All mutations	R	1.9836580766813325	>1
456	N	A	All mutations	A	1.9987429289754872	>1
456	N	S	All mutations	S	0.9874292897548711	1
456	N	T	All mutations	T	1.0012570710245128	1
456	N	W	All mutations	W	2.9836580766813325	>1
456	N	F	All mutations	F	2.001257071024513	>1
456	N	E	All mutations	E	2.0125707102451287	>1
456	N	M	All mutations	M	2.0	>1
456	N	Q	All mutations	Q	2.013827781269642	>1
456	N	G	All mutations	G	1.9836580766813325	>1
457	V	H	All mutations	H	2.6926461345065995	>1
457	V	L	All mutations	L	1.0	1
457	V	P	All mutations	P	2.0	>1
457	V	K	All mutations	K	2.2979258328095535	>1
457	V	E	All mutations	E	1.316781898177247	>1
457	V	S	All mutations	S	1.9956002514142048	>1
457	V	D	All mutations	D	1.7020741671904462	>1
457	V	G	All mutations	G	1.0094280326838467	1
457	V	I	All mutations	I	1.3513513513513513	>1
457	V	W	All mutations	W	2.639220615964802	>1
457	V	V	All mutations	V	0.009428032683846637	1
457	V	Y	All mutations	Y	2.6926461345065995	>1
457	V	R	All mutations	R	1.9949717159019484	>1
457	V	M	All mutations	M	1.6297925832809554	>1
457	V	Q	All mutations	Q	2.3073538654934005	>1
457	V	T	All mutations	T	1.9905719673161533	>1
457	V	A	All mutations	A	1.0094280326838467	1
457	V	N	All mutations	N	2.683218101822753	>1
457	V	F	All mutations	F	1.6926461345065997	>1
457	V	C	All mutations	C	2.6926461345065995	>1
458	M	T	All mutations	T	1.0	1
458	M	N	All mutations	N	2.0	>1
458	M	C	All mutations	C	3.0	>1
458	M	M	All mutations	M	0.0	0
458	M	K	All mutations	K	1.0	1
458	M	F	All mutations	F	2.0	>1
458	M	H	All mutations	H	3.0	>1
458	M	I	All mutations	I	1.0	1
458	M	E	All mutations	E	2.0	>1
458	M	W	All mutations	W	2.0	>1
458	M	D	All mutations	D	3.0	>1
458	M	G	All mutations	G	2.0	>1
458	M	V	All mutations	V	1.0	1
458	M	R	All mutations	R	1.0	1
458	M	Q	All mutations	Q	2.0	>1
458	M	A	All mutations	A	2.0	>1
458	M	S	All mutations	S	2.0	>1
458	M	P	All mutations	P	2.0	>1
458	M	Y	All mutations	Y	3.0	>1
458	M	L	All mutations	L	1.0	1
459	G	P	All mutations	P	2.0	>1
459	G	H	All mutations	H	2.9981143934632306	>1
459	G	W	All mutations	W	1.4198617221873036	>1
459	G	F	All mutations	F	2.9981143934632306	>1
459	G	E	All mutations	E	1.0018856065367694	1
459	G	M	All mutations	M	2.4198617221873038	>1
459	G	Y	All mutations	Y	2.9981143934632306	>1
459	G	A	All mutations	A	1.0	1
459	G	C	All mutations	C	1.9981143934632306	>1
459	G	G	All mutations	G	0.0	0
459	G	D	All mutations	D	1.9981143934632306	>1
459	G	S	All mutations	S	1.9981143934632306	>1
459	G	T	All mutations	T	2.0	>1
459	G	R	All mutations	R	1.0	1
459	G	K	All mutations	K	2.0018856065367694	>1
459	G	L	All mutations	L	2.0	>1
459	G	N	All mutations	N	2.9981143934632306	>1
459	G	V	All mutations	V	1.0	1
459	G	I	All mutations	I	2.5801382778126962	>1
459	G	Q	All mutations	Q	2.0018856065367694	>1
460	M	I	All mutations	I	1.0	1
460	M	G	All mutations	G	2.0	>1
460	M	F	All mutations	F	2.0	>1
460	M	C	All mutations	C	3.0	>1
460	M	A	All mutations	A	2.0	>1
460	M	Y	All mutations	Y	3.0	>1
460	M	R	All mutations	R	1.0	1
460	M	P	All mutations	P	2.0	>1
460	M	Q	All mutations	Q	2.0	>1
460	M	L	All mutations	L	1.0	1
460	M	S	All mutations	S	2.0	>1
460	M	W	All mutations	W	2.0	>1
460	M	H	All mutations	H	3.0	>1
460	M	D	All mutations	D	3.0	>1
460	M	T	All mutations	T	1.0	1
460	M	E	All mutations	E	2.0	>1
460	M	K	All mutations	K	1.0	1
460	M	V	All mutations	V	1.0	1
460	M	M	All mutations	M	0.0	0
460	M	N	All mutations	N	2.0	>1
461	I	N	All mutations	N	1.162162162162162	>1
461	I	D	All mutations	D	1.9610307982401005	>1
461	I	W	All mutations	W	2.9949717159019484	>1
461	I	L	All mutations	L	1.0	1
461	I	Y	All mutations	Y	2.0559396605908233	>1
461	I	R	All mutations	R	1.9421747328724073	>1
461	I	G	All mutations	G	1.9013199245757386	>1
461	I	P	All mutations	P	2.0	>1
461	I	A	All mutations	A	1.9013199245757386	>1
461	I	H	All mutations	H	2.059710873664362	>1
461	I	C	All mutations	C	2.0559396605908233	>1
461	I	Q	All mutations	Q	2.940289126335638	>1
461	I	E	All mutations	E	2.8416090509113765	>1
461	I	V	All mutations	V	0.9013199245757385	1
461	I	F	All mutations	F	1.0559396605908233	1
461	I	M	All mutations	M	1.1011942174732872	>1
461	I	I	All mutations	I	0.10370835952231301	1
461	I	T	All mutations	T	1.1024512884978002	>1
461	I	S	All mutations	S	1.156505342551854	>1
461	I	K	All mutations	K	2.042740414833438	>1
462	G	V	All mutations	V	1.0	1
462	G	H	All mutations	H	2.996857322438718	>1
462	G	C	All mutations	C	1.9968573224387178	>1
462	G	S	All mutations	S	1.9968573224387178	>1
462	G	N	All mutations	N	2.996857322438718	>1
462	G	I	All mutations	I	2.585166561910748	>1
462	G	G	All mutations	G	0.0	0
462	G	L	All mutations	L	2.0	>1
462	G	Q	All mutations	Q	2.003142677561282	>1
462	G	E	All mutations	E	1.0031426775612822	1
462	G	R	All mutations	R	1.0	1
462	G	K	All mutations	K	2.003142677561282	>1
462	G	T	All mutations	T	2.0	>1
462	G	D	All mutations	D	1.9968573224387178	>1
462	G	P	All mutations	P	2.0	>1
462	G	A	All mutations	A	1.0	1
462	G	F	All mutations	F	2.996857322438718	>1
462	G	W	All mutations	W	1.414833438089252	>1
462	G	Y	All mutations	Y	2.996857322438718	>1
462	G	M	All mutations	M	2.414833438089252	>1
463	I	P	All mutations	P	2.0	>1
463	I	G	All mutations	G	1.9899434318038969	>1
463	I	R	All mutations	R	1.0100565681961031	1
463	I	F	All mutations	F	2.0	>1
463	I	S	All mutations	S	2.0	>1
463	I	A	All mutations	A	1.9899434318038969	>1
463	I	N	All mutations	N	2.010056568196103	>1
463	I	Q	All mutations	Q	2.0	>1
463	I	K	All mutations	K	1.0100565681961031	1
463	I	I	All mutations	I	0.018856065367693273	1
463	I	M	All mutations	M	1.0012570710245128	1
463	I	Y	All mutations	Y	3.0	>1
463	I	E	All mutations	E	1.9899434318038969	>1
463	I	D	All mutations	D	2.989943431803897	>1
463	I	C	All mutations	C	3.0	>1
463	I	W	All mutations	W	2.9912005028284097	>1
463	I	V	All mutations	V	0.9899434318038969	1
463	I	H	All mutations	H	3.0	>1
463	I	T	All mutations	T	1.0100565681961031	1
463	I	L	All mutations	L	1.0	1
464	L	V	All mutations	V	1.0	1
464	L	Q	All mutations	Q	1.8372093023255813	>1
464	L	A	All mutations	A	2.0	>1
464	L	G	All mutations	G	2.0	>1
464	L	P	All mutations	P	1.8353236957888122	>1
464	L	F	All mutations	F	1.1678189817724702	>1
464	L	N	All mutations	N	2.993086109365179	>1
464	L	M	All mutations	M	1.262727844123193	>1
464	L	K	All mutations	K	1.9968573224387178	>1
464	L	C	All mutations	C	2.16781898177247	>1
464	L	D	All mutations	D	2.9981143934632306	>1
464	L	W	All mutations	W	1.437460716530484	>1
464	L	I	All mutations	I	1.727215587680704	>1
464	L	R	All mutations	R	1.8302954116907606	>1
464	L	E	All mutations	E	2.0018856065367694	>1
464	L	T	All mutations	T	1.9949717159019484	>1
464	L	Y	All mutations	Y	2.16781898177247	>1
464	L	S	All mutations	S	1.1697045883092394	>1
464	L	L	All mutations	L	0.00502828409805154	1
464	L	H	All mutations	H	2.8334380892520428	>1
465	P	H	All mutations	H	1.0175989943431805	1
465	P	A	All mutations	A	1.0006285355122564	1
465	P	S	All mutations	S	0.9993714644877436	1
465	P	G	All mutations	G	2.0	>1
465	P	I	All mutations	I	2.001257071024513	>1
465	P	W	All mutations	W	2.9974858579509744	>1
465	P	E	All mutations	E	2.9824010056568198	>1
465	P	P	All mutations	P	0.0018856065367693275	1
465	P	D	All mutations	D	2.0163419233186675	>1
465	P	Q	All mutations	Q	1.9836580766813325	>1
465	P	N	All mutations	N	2.0163419233186675	>1
465	P	V	All mutations	V	2.0	>1
465	P	Y	All mutations	Y	2.0150848522941547	>1
465	P	K	All mutations	K	2.9824010056568198	>1
465	P	R	All mutations	R	1.0012570710245128	1
465	P	T	All mutations	T	1.0006285355122564	1
465	P	F	All mutations	F	2.015713387806411	>1
465	P	M	All mutations	M	2.998742928975487	>1
465	P	C	All mutations	C	2.015713387806411	>1
465	P	L	All mutations	L	1.0012570710245128	1
466	D	Y	All mutations	Y	1.0012570710245128	1
466	D	Q	All mutations	Q	2.0	>1
466	D	T	All mutations	T	2.0	>1
466	D	D	All mutations	D	0.001257071024512885	1
466	D	W	All mutations	W	2.998742928975487	>1
466	D	H	All mutations	H	1.0012570710245128	1
466	D	I	All mutations	I	2.0006285355122566	>1
466	D	V	All mutations	V	1.0	1
466	D	S	All mutations	S	1.9993714644877436	>1
466	D	C	All mutations	C	2.0	>1
466	D	F	All mutations	F	2.0006285355122566	>1
466	D	A	All mutations	A	1.0	1
466	D	K	All mutations	K	2.0	>1
466	D	M	All mutations	M	2.9993714644877434	>1
466	D	N	All mutations	N	1.0012570710245128	1
466	D	R	All mutations	R	1.9993714644877436	>1
466	D	P	All mutations	P	2.0	>1
466	D	E	All mutations	E	1.0	1
466	D	L	All mutations	L	2.0	>1
466	D	G	All mutations	G	0.9993714644877436	1
467	M	S	All mutations	S	1.9981143934632306	>1
467	M	W	All mutations	W	2.0	>1
467	M	I	All mutations	I	1.0	1
467	M	M	All mutations	M	0.00251414204902577	1
467	M	L	All mutations	L	0.9987429289754871	1
467	M	G	All mutations	G	2.0	>1
467	M	E	All mutations	E	2.0006285355122566	>1
467	M	D	All mutations	D	2.9993714644877434	>1
467	M	H	All mutations	H	2.9993714644877434	>1
467	M	A	All mutations	A	2.0	>1
467	M	T	All mutations	T	1.0012570710245128	1
467	M	P	All mutations	P	2.0	>1
467	M	Y	All mutations	Y	2.9981143934632306	>1
467	M	F	All mutations	F	1.9981143934632306	>1
467	M	N	All mutations	N	2.0006285355122566	>1
467	M	K	All mutations	K	1.0018856065367694	1
467	M	C	All mutations	C	2.9981143934632306	>1
467	M	Q	All mutations	Q	2.0006285355122566	>1
467	M	R	All mutations	R	1.0018856065367694	1
467	M	V	All mutations	V	1.0	1
468	T	A	All mutations	A	0.9974858579509742	1
468	T	Y	All mutations	Y	2.0087994971715903	>1
468	T	V	All mutations	V	1.9974858579509742	>1
468	T	K	All mutations	K	1.9937146448774357	>1
468	T	G	All mutations	G	1.9974858579509742	>1
468	T	H	All mutations	H	2.0087994971715903	>1
468	T	F	All mutations	F	2.0087994971715903	>1
468	T	L	All mutations	L	2.0	>1
468	T	W	All mutations	W	2.9993714644877434	>1
468	T	E	All mutations	E	2.988686360779384	>1
468	T	C	All mutations	C	2.0087994971715903	>1
468	T	I	All mutations	I	1.0031426775612822	1
468	T	S	All mutations	S	1.0	1
468	T	D	All mutations	D	2.0062853551225643	>1
468	T	N	All mutations	N	1.011313639220616	1
468	T	Q	All mutations	Q	2.9912005028284097	>1
468	T	M	All mutations	M	2.0018856065367694	>1
468	T	T	All mutations	T	0.00251414204902577	1
468	T	P	All mutations	P	1.0	1
468	T	R	All mutations	R	1.9912005028284099	>1
469	P	R	All mutations	R	1.0	1
469	P	C	All mutations	C	2.5914519170333126	>1
469	P	D	All mutations	D	2.5914519170333126	>1
469	P	Q	All mutations	Q	1.4085480829666877	>1
469	P	V	All mutations	V	2.0	>1
469	P	Y	All mutations	Y	2.5914519170333126	>1
469	P	K	All mutations	K	2.4085480829666874	>1
469	P	L	All mutations	L	1.0	1
469	P	S	All mutations	S	1.0	1
469	P	F	All mutations	F	2.5914519170333126	>1
469	P	G	All mutations	G	2.0	>1
469	P	M	All mutations	M	2.992457573852923	>1
469	P	W	All mutations	W	2.992457573852923	>1
469	P	T	All mutations	T	1.0	1
469	P	E	All mutations	E	2.4085480829666874	>1
469	P	N	All mutations	N	2.5914519170333126	>1
469	P	H	All mutations	H	1.5914519170333123	>1
469	P	I	All mutations	I	2.007542426147077	>1
469	P	P	All mutations	P	0.0	0
469	P	A	All mutations	A	1.0	1
470	S	Y	All mutations	Y	1.96291640477687	>1
470	S	I	All mutations	I	1.0	1
470	S	V	All mutations	V	2.0	>1
470	S	F	All mutations	F	2.0	>1
470	S	Q	All mutations	Q	2.9629164047768697	>1
470	S	E	All mutations	E	2.9629164047768697	>1
470	S	N	All mutations	N	0.9629164047768699	1
470	S	C	All mutations	C	1.03708359522313	1
470	S	K	All mutations	K	1.96291640477687	>1
470	S	G	All mutations	G	1.03708359522313	1
470	S	H	All mutations	H	1.96291640477687	>1
470	S	S	All mutations	S	0.03708359522313011	1
470	S	T	All mutations	T	1.0	1
470	S	M	All mutations	M	2.0	>1
470	S	L	All mutations	L	2.0	>1
470	S	A	All mutations	A	2.0	>1
470	S	W	All mutations	W	2.0370835952231303	>1
470	S	P	All mutations	P	2.0	>1
470	S	R	All mutations	R	1.03708359522313	1
470	S	D	All mutations	D	1.96291640477687	>1
471	T	Q	All mutations	Q	2.4594594594594597	>1
471	T	E	All mutations	E	2.455688246385921	>1
471	T	H	All mutations	H	2.5405405405405403	>1
471	T	W	All mutations	W	2.8774355751099936	>1
471	T	M	All mutations	M	1.8761785040854808	>1
471	T	N	All mutations	N	1.5461973601508485	>1
471	T	L	All mutations	L	1.9893148962916405	>1
471	T	D	All mutations	D	2.536769327467002	>1
471	T	I	All mutations	I	1.1175361407919548	>1
471	T	F	All mutations	F	2.529855436832181	>1
471	T	G	All mutations	G	1.9962287869264614	>1
471	T	C	All mutations	C	2.5386549340037714	>1
471	T	V	All mutations	V	1.987429289754871	>1
471	T	P	All mutations	P	1.0087994971715901	1
471	T	A	All mutations	A	1.0050282840980516	1
471	T	Y	All mutations	Y	2.5386549340037714	>1
471	T	S	All mutations	S	0.9993714644877436	1
471	T	T	All mutations	T	0.014456316781898177	1
471	T	R	All mutations	R	1.4619736015084852	>1
471	T	K	All mutations	K	1.4651162790697674	>1
472	E	C	All mutations	C	2.9905719673161535	>1
472	E	T	All mutations	T	2.0	>1
472	E	M	All mutations	M	2.2269013199245755	>1
472	E	F	All mutations	F	2.9918290383406663	>1
472	E	N	All mutations	N	1.993086109365179	>1
472	E	G	All mutations	G	0.9987429289754871	1
472	E	I	All mutations	I	2.7730986800754245	>1
472	E	A	All mutations	A	1.0	1
472	E	D	All mutations	D	0.9930861093651792	1
472	E	P	All mutations	P	2.0	>1
472	E	L	All mutations	L	2.0	>1
472	E	H	All mutations	H	1.993086109365179	>1
472	E	V	All mutations	V	1.0	1
472	E	E	All mutations	E	0.009428032683846637	1
472	E	K	All mutations	K	1.0094280326838467	1
472	E	Y	All mutations	Y	1.993086109365179	>1
472	E	R	All mutations	R	1.9987429289754872	>1
472	E	Q	All mutations	Q	1.0094280326838467	1
472	E	S	All mutations	S	2.0	>1
472	E	W	All mutations	W	2.2256442489000627	>1
473	M	S	All mutations	S	1.9767441860465116	>1
473	M	R	All mutations	R	1.0414833438089253	1
473	M	L	All mutations	L	0.9321181646763043	1
473	M	T	All mutations	T	1.0898805782526713	1
473	M	D	All mutations	D	2.978629792583281	>1
473	M	I	All mutations	I	1.0886235072281585	1
473	M	Q	All mutations	Q	1.950345694531741	>1
473	M	H	All mutations	H	2.950345694531741	>1
473	M	A	All mutations	A	1.9780012570710246	>1
473	M	P	All mutations	P	1.9497171590194846	>1
473	M	Y	All mutations	Y	2.9780012570710244	>1
473	M	K	All mutations	K	1.0905091137649277	1
473	M	F	All mutations	F	1.9811439346323068	>1
473	M	W	All mutations	W	1.9830295411690761	>1
473	M	G	All mutations	G	1.978629792583281	>1
473	M	V	All mutations	V	0.9817724701445631	1
473	M	N	All mutations	N	2.0905091137649277	>1
473	M	E	All mutations	E	1.978629792583281	>1
473	M	C	All mutations	C	2.9780012570710244	>1
473	M	M	All mutations	M	0.09868007542426147	1
474	S	Q	All mutations	Q	2.0502828409805156	>1
474	S	S	All mutations	S	0.00251414204902577	1
474	S	I	All mutations	I	2.2162162162162162	>1
474	S	C	All mutations	C	1.9522313010685104	>1
474	S	H	All mutations	H	2.9497171590194844	>1
474	S	K	All mutations	K	2.0477686989314896	>1
474	S	W	All mutations	W	1.7837837837837838	>1
474	S	Y	All mutations	Y	1.9522313010685104	>1
474	S	R	All mutations	R	1.9974858579509742	>1
474	S	M	All mutations	M	2.778755499685732	>1
474	S	T	All mutations	T	0.9974858579509742	1
474	S	D	All mutations	D	2.9497171590194844	>1
474	S	E	All mutations	E	2.0502828409805156	>1
474	S	N	All mutations	N	2.947203016970459	>1
474	S	P	All mutations	P	1.0	1
474	S	A	All mutations	A	1.0	1
474	S	F	All mutations	F	1.9522313010685104	>1
474	S	V	All mutations	V	2.0	>1
474	S	L	All mutations	L	1.0527969830295412	1
474	S	G	All mutations	G	2.0	>1
475	L	M	All mutations	M	1.288497800125707	>1
475	L	S	All mutations	S	1.7265870521684474	>1
475	L	I	All mutations	I	1.7027027027027026	>1
475	L	G	All mutations	G	2.0	>1
475	L	R	All mutations	R	1.2734129478315526	>1
475	L	C	All mutations	C	2.7165304839723445	>1
475	L	A	All mutations	A	2.0	>1
475	L	W	All mutations	W	2.0194846008799496	>1
475	L	D	All mutations	D	2.989943431803897	>1
475	L	Q	All mutations	Q	1.2878692646134506	>1
475	L	V	All mutations	V	1.0	1
475	L	K	All mutations	K	2.005656819610308	>1
475	L	F	All mutations	F	1.7165304839723445	>1
475	L	Y	All mutations	Y	2.7165304839723445	>1
475	L	N	All mutations	N	2.985543683218102	>1
475	L	E	All mutations	E	2.010056568196103	>1
475	L	H	All mutations	H	2.2677561282212446	>1
475	L	P	All mutations	P	1.2778126964173475	>1
475	L	L	All mutations	L	0.0043997485857950975	1
475	L	T	All mutations	T	1.9956002514142048	>1
476	R	M	All mutations	M	1.5556253928346953	>1
476	R	W	All mutations	W	1.5549968573224386	>1
476	R	D	All mutations	D	3.0	>1
476	R	Q	All mutations	Q	1.9993714644877436	>1
476	R	E	All mutations	E	2.0	>1
476	R	R	All mutations	R	0.0	0
476	R	A	All mutations	A	2.0	>1
476	R	F	All mutations	F	3.0	>1
476	R	S	All mutations	S	1.0006285355122564	1
476	R	P	All mutations	P	1.9993714644877436	>1
476	R	N	All mutations	N	2.0006285355122566	>1
476	R	T	All mutations	T	1.0006285355122564	1
476	R	C	All mutations	C	2.0	>1
476	R	H	All mutations	H	2.9993714644877434	>1
476	R	L	All mutations	L	1.9993714644877436	>1
476	R	Y	All mutations	Y	3.0	>1
476	R	K	All mutations	K	1.0006285355122564	1
476	R	G	All mutations	G	1.0	1
476	R	V	All mutations	V	2.0	>1
476	R	I	All mutations	I	1.4456316781898177	>1
477	G	P	All mutations	P	2.0	>1
477	G	Q	All mutations	Q	2.0025141420490256	>1
477	G	L	All mutations	L	2.0	>1
477	G	I	All mutations	I	2.153362664990572	>1
477	G	N	All mutations	N	2.9974858579509744	>1
477	G	V	All mutations	V	1.0	1
477	G	W	All mutations	W	1.846637335009428	>1
477	G	D	All mutations	D	1.9974858579509742	>1
477	G	E	All mutations	E	1.0025141420490258	1
477	G	S	All mutations	S	1.9974858579509742	>1
477	G	H	All mutations	H	2.9974858579509744	>1
477	G	C	All mutations	C	1.9974858579509742	>1
477	G	R	All mutations	R	1.0	1
477	G	K	All mutations	K	2.0025141420490256	>1
477	G	A	All mutations	A	1.0	1
477	G	M	All mutations	M	2.846637335009428	>1
477	G	G	All mutations	G	0.0	0
477	G	Y	All mutations	Y	2.9974858579509744	>1
477	G	F	All mutations	F	2.9974858579509744	>1
477	G	T	All mutations	T	2.0	>1
478	I	Q	All mutations	Q	2.0	>1
478	I	N	All mutations	N	2.541169076052797	>1
478	I	G	All mutations	G	1.458830923947203	>1
478	I	S	All mutations	S	2.0	>1
478	I	D	All mutations	D	2.458830923947203	>1
478	I	P	All mutations	P	2.0	>1
478	I	A	All mutations	A	1.458830923947203	>1
478	I	I	All mutations	I	0.9365179132620993	1
478	I	W	All mutations	W	2.604651162790698	>1
478	I	E	All mutations	E	1.458830923947203	>1
478	I	H	All mutations	H	3.0	>1
478	I	C	All mutations	C	3.0	>1
478	I	R	All mutations	R	1.541169076052797	>1
478	I	K	All mutations	K	1.541169076052797	>1
478	I	V	All mutations	V	0.45883092394720304	1
478	I	T	All mutations	T	1.541169076052797	>1
478	I	F	All mutations	F	2.0	>1
478	I	M	All mutations	M	1.1458202388434946	>1
478	I	L	All mutations	L	1.0	1
478	I	Y	All mutations	Y	3.0	>1
479	R	S	All mutations	S	1.0018856065367694	1
479	R	Q	All mutations	Q	1.9981143934632306	>1
479	R	C	All mutations	C	2.0006285355122566	>1
479	R	H	All mutations	H	2.9981143934632306	>1
479	R	T	All mutations	T	1.0012570710245128	1
479	R	Y	All mutations	Y	2.9993714644877434	>1
479	R	R	All mutations	R	0.0006285355122564425	1
479	R	E	All mutations	E	1.9993714644877436	>1
479	R	D	All mutations	D	2.9993714644877434	>1
479	R	L	All mutations	L	1.9987429289754872	>1
479	R	N	All mutations	N	2.0006285355122566	>1
479	R	G	All mutations	G	1.0006285355122564	1
479	R	A	All mutations	A	2.0	>1
479	R	W	All mutations	W	1.9792583280955374	>1
479	R	K	All mutations	K	1.0006285355122564	1
479	R	V	All mutations	V	2.0	>1
479	R	F	All mutations	F	3.0	>1
479	R	M	All mutations	M	1.9798868636077938	>1
479	R	I	All mutations	I	1.022627278441232	1
479	R	P	All mutations	P	1.9987429289754872	>1
480	V	Q	All mutations	Q	2.992457573852923	>1
480	V	G	All mutations	G	1.0477686989314896	1
480	V	S	All mutations	S	1.951602765556254	>1
480	V	K	All mutations	K	2.9446888749214333	>1
480	V	E	All mutations	E	2.0402262727844125	>1
480	V	Y	All mutations	Y	2.007542426147077	>1
480	V	A	All mutations	A	1.0471401634192332	1
480	V	C	All mutations	C	2.007542426147077	>1
480	V	W	All mutations	W	2.995600251414205	>1
480	V	M	All mutations	M	1.9484600879949716	>1
480	V	F	All mutations	F	1.0081709616593337	1
480	V	N	All mutations	N	1.9597737272155877	>1
480	V	I	All mutations	I	0.957259585166562	1
480	V	P	All mutations	P	1.9993714644877436	>1
480	V	H	All mutations	H	2.007542426147077	>1
480	V	V	All mutations	V	0.04839723444374607	1
480	V	T	All mutations	T	1.951602765556254	>1
480	V	L	All mutations	L	1.0006285355122564	1
480	V	D	All mutations	D	1.055311125078567	1
480	V	R	All mutations	R	2.0	>1
481	S	H	All mutations	H	2.0	>1
481	S	I	All mutations	I	1.0012570710245128	1
481	S	K	All mutations	K	2.001257071024513	>1
481	S	F	All mutations	F	1.9987429289754872	>1
481	S	L	All mutations	L	2.0	>1
481	S	M	All mutations	M	2.001257071024513	>1
481	S	A	All mutations	A	2.0	>1
481	S	W	All mutations	W	1.9987429289754872	>1
481	S	N	All mutations	N	1.0012570710245128	1
481	S	S	All mutations	S	0.001257071024512885	1
481	S	G	All mutations	G	1.0	1
481	S	T	All mutations	T	1.0012570710245128	1
481	S	Y	All mutations	Y	1.9987429289754872	>1
481	S	D	All mutations	D	2.0	>1
481	S	E	All mutations	E	3.0	>1
481	S	R	All mutations	R	1.0	1
481	S	V	All mutations	V	2.0	>1
481	S	Q	All mutations	Q	3.0	>1
481	S	P	All mutations	P	2.0	>1
481	S	C	All mutations	C	0.9987429289754871	1
482	K	P	All mutations	P	1.9993714644877436	>1
482	K	C	All mutations	C	2.9880578252671275	>1
482	K	S	All mutations	S	1.987429289754871	>1
482	K	V	All mutations	V	2.0	>1
482	K	F	All mutations	F	3.0	>1
482	K	N	All mutations	N	1.012570710245129	1
482	K	Y	All mutations	Y	2.0125707102451287	>1
482	K	E	All mutations	E	1.012570710245129	1
482	K	I	All mutations	I	1.4506599622878693	>1
482	K	Q	All mutations	Q	1.012570710245129	1
482	K	A	All mutations	A	1.9993714644877436	>1
482	K	L	All mutations	L	2.0	>1
482	K	G	All mutations	G	1.9880578252671275	>1
482	K	D	All mutations	D	2.0125707102451287	>1
482	K	T	All mutations	T	0.9993714644877436	1
482	K	H	All mutations	H	2.0125707102451287	>1
482	K	K	All mutations	K	0.01257071024512885	1
482	K	M	All mutations	M	1.5493400377121307	>1
482	K	R	All mutations	R	0.9880578252671276	1
482	K	W	All mutations	W	2.537397862979258	>1
483	M	A	All mutations	A	1.9956002514142048	>1
483	M	W	All mutations	W	2.0	>1
483	M	K	All mutations	K	1.0006285355122564	1
483	M	E	All mutations	E	1.9993714644877436	>1
483	M	V	All mutations	V	1.0031426775612822	1
483	M	I	All mutations	I	1.0043997485857952	1
483	M	R	All mutations	R	1.0006285355122564	1
483	M	L	All mutations	L	1.0037712130735386	1
483	M	P	All mutations	P	1.9962287869264614	>1
483	M	H	All mutations	H	3.0	>1
483	M	M	All mutations	M	0.0043997485857950975	1
483	M	C	All mutations	C	3.0	>1
483	M	N	All mutations	N	2.0006285355122566	>1
483	M	D	All mutations	D	2.9993714644877434	>1
483	M	Y	All mutations	Y	3.0	>1
483	M	F	All mutations	F	2.003771213073539	>1
483	M	Q	All mutations	Q	2.0	>1
483	M	S	All mutations	S	1.9962287869264614	>1
483	M	T	All mutations	T	0.9968573224387178	1
483	M	G	All mutations	G	1.9993714644877436	>1
484	G	R	All mutations	R	1.0	1
484	G	G	All mutations	G	0.0	0
484	G	N	All mutations	N	2.998742928975487	>1
484	G	V	All mutations	V	1.0	1
484	G	Y	All mutations	Y	2.998742928975487	>1
484	G	F	All mutations	F	2.998742928975487	>1
484	G	Q	All mutations	Q	2.001257071024513	>1
484	G	S	All mutations	S	1.9987429289754872	>1
484	G	L	All mutations	L	2.0	>1
484	G	E	All mutations	E	1.0012570710245128	1
484	G	A	All mutations	A	1.0	1
484	G	P	All mutations	P	2.0	>1
484	G	D	All mutations	D	1.9987429289754872	>1
484	G	T	All mutations	T	2.0	>1
484	G	W	All mutations	W	1.9277184160905092	>1
484	G	H	All mutations	H	2.998742928975487	>1
484	G	K	All mutations	K	2.001257071024513	>1
484	G	M	All mutations	M	2.927718416090509	>1
484	G	C	All mutations	C	1.9987429289754872	>1
484	G	I	All mutations	I	2.072281583909491	>1
485	V	Y	All mutations	Y	2.9522313010685104	>1
485	V	Q	All mutations	Q	2.0477686989314896	>1
485	V	H	All mutations	H	2.9522313010685104	>1
485	V	M	All mutations	M	1.7448145820238843	>1
485	V	T	All mutations	T	2.0	>1
485	V	C	All mutations	C	2.9522313010685104	>1
485	V	L	All mutations	L	1.0	1
485	V	N	All mutations	N	2.9522313010685104	>1
485	V	E	All mutations	E	1.0477686989314896	1
485	V	P	All mutations	P	2.0	>1
485	V	W	All mutations	W	2.7448145820238845	>1
485	V	K	All mutations	K	2.0477686989314896	>1
485	V	D	All mutations	D	1.9522313010685104	>1
485	V	I	All mutations	I	1.2551854179761157	>1
485	V	A	All mutations	A	1.0	1
485	V	V	All mutations	V	0.0	0
485	V	R	All mutations	R	2.0	>1
485	V	F	All mutations	F	1.9522313010685104	>1
485	V	G	All mutations	G	1.0	1
485	V	S	All mutations	S	2.0	>1
486	D	S	All mutations	S	2.0	>1
486	D	R	All mutations	R	2.0	>1
486	D	A	All mutations	A	1.0	1
486	D	C	All mutations	C	2.0	>1
486	D	E	All mutations	E	1.0	1
486	D	G	All mutations	G	1.0	1
486	D	N	All mutations	N	1.0	1
486	D	W	All mutations	W	3.0	>1
486	D	T	All mutations	T	2.0	>1
486	D	V	All mutations	V	1.0	1
486	D	P	All mutations	P	2.0	>1
486	D	M	All mutations	M	3.0	>1
486	D	Y	All mutations	Y	1.0	1
486	D	D	All mutations	D	0.0	0
486	D	K	All mutations	K	2.0	>1
486	D	H	All mutations	H	1.0	1
486	D	L	All mutations	L	2.0	>1
486	D	I	All mutations	I	2.0	>1
486	D	F	All mutations	F	2.0	>1
486	D	Q	All mutations	Q	2.0	>1
487	E	L	All mutations	L	2.0	>1
487	E	V	All mutations	V	1.0	1
487	E	E	All mutations	E	0.0	0
487	E	Q	All mutations	Q	1.0	1
487	E	N	All mutations	N	2.0	>1
487	E	I	All mutations	I	2.0188560653676935	>1
487	E	D	All mutations	D	1.0	1
487	E	T	All mutations	T	2.0	>1
487	E	G	All mutations	G	1.0	1
487	E	P	All mutations	P	2.0	>1
487	E	R	All mutations	R	2.0	>1
487	E	F	All mutations	F	3.0	>1
487	E	A	All mutations	A	1.0	1
487	E	M	All mutations	M	2.9811439346323065	>1
487	E	C	All mutations	C	3.0	>1
487	E	H	All mutations	H	2.0	>1
487	E	W	All mutations	W	2.9811439346323065	>1
487	E	S	All mutations	S	2.0	>1
487	E	K	All mutations	K	1.0	1
487	E	Y	All mutations	Y	2.0	>1
488	Y	W	All mutations	W	1.9993714644877436	>1
488	Y	L	All mutations	L	2.0	>1
488	Y	A	All mutations	A	2.0	>1
488	Y	Q	All mutations	Q	2.0006285355122566	>1
488	Y	P	All mutations	P	2.0	>1
488	Y	K	All mutations	K	2.0006285355122566	>1
488	Y	C	All mutations	C	0.9993714644877436	1
488	Y	R	All mutations	R	1.9993714644877436	>1
488	Y	F	All mutations	F	1.0	1
488	Y	V	All mutations	V	2.0	>1
488	Y	D	All mutations	D	1.0006285355122564	1
488	Y	Y	All mutations	Y	0.0006285355122564425	1
488	Y	N	All mutations	N	1.0006285355122564	1
488	Y	I	All mutations	I	2.0	>1
488	Y	G	All mutations	G	1.9993714644877436	>1
488	Y	E	All mutations	E	2.0006285355122566	>1
488	Y	T	All mutations	T	2.0	>1
488	Y	S	All mutations	S	1.0	1
488	Y	M	All mutations	M	3.0	>1
488	Y	H	All mutations	H	1.0006285355122564	1
489	S	N	All mutations	N	2.0125707102451287	>1
489	S	G	All mutations	G	2.0	>1
489	S	W	All mutations	W	1.9962287869264614	>1
489	S	E	All mutations	E	2.9874292897548713	>1
489	S	S	All mutations	S	0.0	0
489	S	Y	All mutations	Y	1.012570710245129	1
489	S	F	All mutations	F	1.012570710245129	1
489	S	R	All mutations	R	2.0	>1
489	S	V	All mutations	V	2.0	>1
489	S	Q	All mutations	Q	2.9874292897548713	>1
489	S	P	All mutations	P	1.0	1
489	S	L	All mutations	L	1.987429289754871	>1
489	S	C	All mutations	C	1.012570710245129	1
489	S	K	All mutations	K	2.9874292897548713	>1
489	S	T	All mutations	T	1.0	1
489	S	M	All mutations	M	2.996228786926461	>1
489	S	A	All mutations	A	1.0	1
489	S	H	All mutations	H	2.0125707102451287	>1
489	S	D	All mutations	D	2.0125707102451287	>1
489	S	I	All mutations	I	2.003771213073539	>1
490	S	M	All mutations	M	2.0	>1
490	S	H	All mutations	H	1.9195474544311755	>1
490	S	C	All mutations	C	1.0804525455688245	1
490	S	Q	All mutations	Q	2.9195474544311755	>1
490	S	T	All mutations	T	1.0	1
490	S	V	All mutations	V	2.0	>1
490	S	S	All mutations	S	0.08045254556882464	1
490	S	K	All mutations	K	1.9195474544311755	>1
490	S	R	All mutations	R	1.0804525455688245	1
490	S	A	All mutations	A	2.0	>1
490	S	N	All mutations	N	0.9195474544311754	1
490	S	F	All mutations	F	2.0	>1
490	S	E	All mutations	E	2.9195474544311755	>1
490	S	P	All mutations	P	2.0	>1
490	S	W	All mutations	W	2.0804525455688245	>1
490	S	I	All mutations	I	1.0	1
490	S	Y	All mutations	Y	1.9195474544311755	>1
490	S	G	All mutations	G	1.0804525455688245	1
490	S	L	All mutations	L	2.0	>1
490	S	D	All mutations	D	1.9195474544311755	>1
491	T	Q	All mutations	Q	2.5329981143934632	>1
491	T	P	All mutations	P	1.0006285355122564	1
491	T	Y	All mutations	Y	2.4670018856065368	>1
491	T	N	All mutations	N	1.4688874921433062	>1
491	T	T	All mutations	T	0.00251414204902577	1
491	T	D	All mutations	D	2.4651162790697674	>1
491	T	K	All mutations	K	1.5348837209302326	>1
491	T	F	All mutations	F	2.46637335009428	>1
491	T	A	All mutations	A	0.9987429289754871	1
491	T	I	All mutations	I	1.0100565681961031	1
491	T	R	All mutations	R	1.534255185417976	>1
491	T	V	All mutations	V	1.9974858579509742	>1
491	T	W	All mutations	W	2.9912005028284097	>1
491	T	C	All mutations	C	2.4670018856065368	>1
491	T	E	All mutations	E	2.531112507856694	>1
491	T	M	All mutations	M	1.9924575738529227	>1
491	T	H	All mutations	H	2.4670018856065368	>1
491	T	S	All mutations	S	1.0	1
491	T	G	All mutations	G	1.9981143934632306	>1
491	T	L	All mutations	L	1.9993714644877436	>1
492	E	T	All mutations	T	2.0	>1
492	E	Q	All mutations	Q	1.0006285355122564	1
492	E	I	All mutations	I	2.7988686360779385	>1
492	E	V	All mutations	V	1.0	1
492	E	M	All mutations	M	2.2011313639220615	>1
492	E	D	All mutations	D	0.9993714644877436	1
492	E	H	All mutations	H	1.9993714644877436	>1
492	E	P	All mutations	P	2.0	>1
492	E	K	All mutations	K	1.0006285355122564	1
492	E	A	All mutations	A	1.0	1
492	E	N	All mutations	N	1.9993714644877436	>1
492	E	C	All mutations	C	2.9993714644877434	>1
492	E	R	All mutations	R	2.0	>1
492	E	W	All mutations	W	2.2011313639220615	>1
492	E	Y	All mutations	Y	1.9993714644877436	>1
492	E	G	All mutations	G	1.0	1
492	E	E	All mutations	E	0.0006285355122564425	1
492	E	S	All mutations	S	2.0	>1
492	E	F	All mutations	F	2.9993714644877434	>1
492	E	L	All mutations	L	2.0	>1
493	R	G	All mutations	G	1.0050282840980516	1
493	R	D	All mutations	D	2.9949717159019484	>1
493	R	E	All mutations	E	1.9949717159019484	>1
493	R	L	All mutations	L	1.6744186046511629	>1
493	R	A	All mutations	A	2.0	>1
493	R	Y	All mutations	Y	2.9949717159019484	>1
493	R	T	All mutations	T	1.3255813953488371	>1
493	R	Q	All mutations	Q	1.6693903205531113	>1
493	R	H	All mutations	H	2.669390320553111	>1
493	R	C	All mutations	C	2.0050282840980516	>1
493	R	N	All mutations	N	2.320553111250786	>1
493	R	I	All mutations	I	1.6568196103079824	>1
493	R	M	All mutations	M	1.994343180389692	>1
493	R	F	All mutations	F	3.0	>1
493	R	S	All mutations	S	1.3306096794468887	>1
493	R	V	All mutations	V	2.0	>1
493	R	W	All mutations	W	1.6737900691389063	>1
493	R	P	All mutations	P	1.6744186046511629	>1
493	R	K	All mutations	K	1.3205531112507856	>1
493	R	R	All mutations	R	0.00502828409805154	1
494	V	Q	All mutations	Q	2.0050282840980516	>1
494	V	R	All mutations	R	1.9748585795097422	>1
494	V	V	All mutations	V	0.026398491514770583	1
494	V	T	All mutations	T	1.9736015084852294	>1
494	V	M	All mutations	M	1.48585795097423	>1
494	V	K	All mutations	K	1.9792583280955374	>1
494	V	H	All mutations	H	2.9949717159019484	>1
494	V	L	All mutations	L	1.0006285355122564	1
494	V	A	All mutations	A	1.0251414204902578	1
494	V	F	All mutations	F	1.9956002514142048	>1
494	V	W	All mutations	W	2.5109993714644876	>1
494	V	E	All mutations	E	1.0307982401005658	1
494	V	G	All mutations	G	1.0257699560025142	1
494	V	C	All mutations	C	2.9949717159019484	>1
494	V	P	All mutations	P	1.9993714644877436	>1
494	V	S	All mutations	S	1.9987429289754872	>1
494	V	Y	All mutations	Y	2.9949717159019484	>1
494	V	N	All mutations	N	2.9692017598994345	>1
494	V	D	All mutations	D	2.0207416719044624	>1
494	V	I	All mutations	I	1.4638592080452546	>1
495	V	F	All mutations	F	1.4996857322438717	>1
495	V	R	All mutations	R	1.9893148962916405	>1
495	V	E	All mutations	E	1.5443117536140791	>1
495	V	C	All mutations	C	2.470144563167819	>1
495	V	D	All mutations	D	1.48585795097423	>1
495	V	I	All mutations	I	1.0402262727844123	1
495	V	T	All mutations	T	1.9591451917033313	>1
495	V	H	All mutations	H	2.4676304211187934	>1
495	V	N	All mutations	N	2.4594594594594597	>1
495	V	Y	All mutations	Y	2.470144563167819	>1
495	V	S	All mutations	S	1.9666876178504085	>1
495	V	W	All mutations	W	2.977372721558768	>1
495	V	K	All mutations	K	2.5179132620993085	>1
495	V	L	All mutations	L	1.0257699560025142	1
495	V	G	All mutations	G	1.0150848522941547	1
495	V	M	All mutations	M	1.9962287869264614	>1
495	V	A	All mutations	A	0.9855436832181018	1
495	V	Q	All mutations	Q	2.5260842237586423	>1
495	V	P	All mutations	P	1.967316153362665	>1
495	V	V	All mutations	V	0.044626021370207415	1
496	V	N	All mutations	N	3.0	>1
496	V	M	All mutations	M	1.5109993714644878	>1
496	V	V	All mutations	V	0.0	0
496	V	Q	All mutations	Q	2.0	>1
496	V	F	All mutations	F	2.0	>1
496	V	I	All mutations	I	1.4890006285355122	>1
496	V	W	All mutations	W	2.5109993714644876	>1
496	V	E	All mutations	E	1.0	1
496	V	G	All mutations	G	1.0	1
496	V	A	All mutations	A	1.0	1
496	V	C	All mutations	C	3.0	>1
496	V	L	All mutations	L	1.0	1
496	V	Y	All mutations	Y	3.0	>1
496	V	D	All mutations	D	2.0	>1
496	V	S	All mutations	S	2.0	>1
496	V	H	All mutations	H	3.0	>1
496	V	P	All mutations	P	2.0	>1
496	V	K	All mutations	K	2.0	>1
496	V	R	All mutations	R	2.0	>1
496	V	T	All mutations	T	2.0	>1
497	S	S	All mutations	S	0.044626021370207415	1
497	S	Q	All mutations	Q	2.9553739786297926	>1
497	S	P	All mutations	P	2.0	>1
497	S	W	All mutations	W	2.0446260213702074	>1
497	S	C	All mutations	C	1.0446260213702074	1
497	S	G	All mutations	G	1.0446260213702074	1
497	S	Y	All mutations	Y	1.9553739786297926	>1
497	S	A	All mutations	A	2.0	>1
497	S	F	All mutations	F	2.0	>1
497	S	D	All mutations	D	1.9553739786297926	>1
497	S	V	All mutations	V	2.0	>1
497	S	E	All mutations	E	2.9553739786297926	>1
497	S	I	All mutations	I	1.0	1
497	S	R	All mutations	R	1.0446260213702074	1
497	S	K	All mutations	K	1.9553739786297926	>1
497	S	T	All mutations	T	1.0	1
497	S	H	All mutations	H	1.9553739786297926	>1
497	S	M	All mutations	M	2.0	>1
497	S	N	All mutations	N	0.9553739786297926	1
497	S	L	All mutations	L	2.0	>1
498	I	S	All mutations	S	1.021370207416719	1
498	I	Y	All mutations	Y	2.0207416719044624	>1
498	I	N	All mutations	N	1.021370207416719	1
498	I	T	All mutations	T	1.0006285355122564	1
498	I	C	All mutations	C	2.0207416719044624	>1
498	I	Q	All mutations	Q	2.9792583280955376	>1
498	I	W	All mutations	W	3.0	>1
498	I	A	All mutations	A	1.9993714644877436	>1
498	I	R	All mutations	R	1.9792583280955374	>1
498	I	F	All mutations	F	1.0207416719044626	1
498	I	V	All mutations	V	0.9993714644877436	1
498	I	I	All mutations	I	0.0006285355122564425	1
498	I	K	All mutations	K	1.9798868636077938	>1
498	I	M	All mutations	M	1.0006285355122564	1
498	I	L	All mutations	L	1.0	1
498	I	G	All mutations	G	1.9993714644877436	>1
498	I	H	All mutations	H	2.0207416719044624	>1
498	I	P	All mutations	P	2.0	>1
498	I	E	All mutations	E	2.978629792583281	>1
498	I	D	All mutations	D	2.0201131363922062	>1
499	D	C	All mutations	C	2.0	>1
499	D	T	All mutations	T	2.0	>1
499	D	I	All mutations	I	2.0	>1
499	D	E	All mutations	E	1.0	1
499	D	H	All mutations	H	1.0	1
499	D	D	All mutations	D	0.0	0
499	D	S	All mutations	S	2.0	>1
499	D	M	All mutations	M	3.0	>1
499	D	F	All mutations	F	2.0	>1
499	D	W	All mutations	W	3.0	>1
499	D	K	All mutations	K	2.0	>1
499	D	R	All mutations	R	2.0	>1
499	D	P	All mutations	P	2.0	>1
499	D	A	All mutations	A	1.0	1
499	D	N	All mutations	N	1.0	1
499	D	Q	All mutations	Q	2.0	>1
499	D	V	All mutations	V	1.0	1
499	D	L	All mutations	L	2.0	>1
499	D	Y	All mutations	Y	1.0	1
499	D	G	All mutations	G	1.0	1
500	R	E	All mutations	E	2.5034569453174105	>1
500	R	M	All mutations	M	2.8969201759899432	>1
500	R	P	All mutations	P	1.0006285355122564	1
500	R	N	All mutations	N	2.4934003771213074	>1
500	R	Q	All mutations	Q	1.5040854808296669	>1
500	R	W	All mutations	W	1.8988057825267128	>1
500	R	Y	All mutations	Y	2.494028912633564	>1
500	R	K	All mutations	K	2.502828409805154	>1
500	R	F	All mutations	F	2.4952859836580767	>1
500	R	I	All mutations	I	2.1018227529855436	>1
500	R	H	All mutations	H	1.4946574481458201	>1
500	R	V	All mutations	V	2.0	>1
500	R	L	All mutations	L	1.0006285355122564	1
500	R	A	All mutations	A	2.0	>1
500	R	D	All mutations	D	2.494028912633564	>1
500	R	S	All mutations	S	1.4959145191703331	>1
500	R	R	All mutations	R	0.001257071024512885	1
500	R	G	All mutations	G	1.0012570710245128	1
500	R	C	All mutations	C	1.4965430546825895	>1
500	R	T	All mutations	T	1.9993714644877436	>1
501	F	C	All mutations	C	1.0	1
501	F	D	All mutations	D	2.0	>1
501	F	I	All mutations	I	1.0	1
501	F	H	All mutations	H	2.0	>1
501	F	Y	All mutations	Y	1.0	1
501	F	F	All mutations	F	0.0	0
501	F	Q	All mutations	Q	3.0	>1
501	F	V	All mutations	V	1.0	1
501	F	R	All mutations	R	2.0	>1
501	F	W	All mutations	W	2.0	>1
501	F	N	All mutations	N	2.0	>1
501	F	E	All mutations	E	3.0	>1
501	F	P	All mutations	P	2.0	>1
501	F	G	All mutations	G	2.0	>1
501	F	T	All mutations	T	2.0	>1
501	F	A	All mutations	A	2.0	>1
501	F	S	All mutations	S	1.0	1
501	F	M	All mutations	M	2.0	>1
501	F	L	All mutations	L	1.0	1
501	F	K	All mutations	K	3.0	>1
502	L	L	All mutations	L	0.0	0
502	L	W	All mutations	W	1.6725329981143935	>1
502	L	K	All mutations	K	2.0	>1
502	L	I	All mutations	I	1.4456316781898177	>1
502	L	C	All mutations	C	2.118164676304211	>1
502	L	V	All mutations	V	1.0	1
502	L	A	All mutations	A	2.0	>1
502	L	E	All mutations	E	2.0	>1
502	L	D	All mutations	D	3.0	>1
502	L	Q	All mutations	Q	1.8818353236957888	>1
502	L	P	All mutations	P	1.8818353236957888	>1
502	L	R	All mutations	R	1.8818353236957888	>1
502	L	T	All mutations	T	2.0	>1
502	L	M	All mutations	M	1.5543683218101823	>1
502	L	F	All mutations	F	1.1181646763042112	>1
502	L	Y	All mutations	Y	2.118164676304211	>1
502	L	N	All mutations	N	3.0	>1
502	L	S	All mutations	S	1.1181646763042112	>1
502	L	H	All mutations	H	2.881835323695789	>1
502	L	G	All mutations	G	2.0	>1
503	R	F	All mutations	F	2.994343180389692	>1
503	R	V	All mutations	V	2.0	>1
503	R	N	All mutations	N	2.0974230043997486	>1
503	R	T	All mutations	T	1.1030798240100566	>1
503	R	A	All mutations	A	2.0	>1
503	R	P	All mutations	P	1.8969201759899434	>1
503	R	Y	All mutations	Y	2.994343180389692	>1
503	R	C	All mutations	C	1.994343180389692	>1
503	R	Q	All mutations	Q	1.9025769956002514	>1
503	R	I	All mutations	I	1.4594594594594594	>1
503	R	W	All mutations	W	1.6436203645505971	>1
503	R	G	All mutations	G	1.0	1
503	R	S	All mutations	S	1.0974230043997486	1
503	R	L	All mutations	L	1.8969201759899434	>1
503	R	R	All mutations	R	0.0	0
503	R	K	All mutations	K	1.1087366436203645	>1
503	R	H	All mutations	H	2.8912633563796355	>1
503	R	D	All mutations	D	2.994343180389692	>1
503	R	E	All mutations	E	2.005656819610308	>1
503	R	M	All mutations	M	1.7467001885606537	>1
504	V	H	All mutations	H	2.082338152105594	>1
504	V	A	All mutations	A	1.0	1
504	V	V	All mutations	V	0.0	0
504	V	F	All mutations	F	1.082338152105594	1
504	V	G	All mutations	G	1.0	1
504	V	C	All mutations	C	2.082338152105594	>1
504	V	R	All mutations	R	2.0	>1
504	V	I	All mutations	I	1.0	1
504	V	T	All mutations	T	2.0	>1
504	V	E	All mutations	E	1.917661847894406	>1
504	V	K	All mutations	K	2.917661847894406	>1
504	V	S	All mutations	S	2.0	>1
504	V	W	All mutations	W	3.0	>1
504	V	M	All mutations	M	2.0	>1
504	V	Q	All mutations	Q	2.917661847894406	>1
504	V	P	All mutations	P	2.0	>1
504	V	Y	All mutations	Y	2.082338152105594	>1
504	V	N	All mutations	N	2.082338152105594	>1
504	V	D	All mutations	D	1.082338152105594	1
504	V	L	All mutations	L	1.0	1
505	R	A	All mutations	A	2.0	>1
505	R	C	All mutations	C	1.988686360779384	>1
505	R	D	All mutations	D	2.9893148962916403	>1
505	R	K	All mutations	K	1.9704588309239472	>1
505	R	N	All mutations	N	2.9490886235072282	>1
505	R	I	All mutations	I	2.195474544311754	>1
505	R	F	All mutations	F	2.988686360779384	>1
505	R	H	All mutations	H	2.0301697045883094	>1
505	R	V	All mutations	V	2.0	>1
505	R	W	All mutations	W	1.7636706473915775	>1
505	R	L	All mutations	L	1.0402262727844123	1
505	R	R	All mutations	R	0.0006285355122564425	1
505	R	M	All mutations	M	2.7240729101194217	>1
505	R	Y	All mutations	Y	2.988686360779384	>1
505	R	Q	All mutations	Q	1.0515399120050284	1
505	R	T	All mutations	T	1.9597737272155877	>1
505	R	E	All mutations	E	2.0106851037083597	>1
505	R	P	All mutations	P	1.0408548082966687	1
505	R	G	All mutations	G	1.0	1
505	R	S	All mutations	S	1.9484600879949716	>1
506	D	G	All mutations	G	1.0	1
506	D	L	All mutations	L	2.0	>1
506	D	A	All mutations	A	1.0	1
506	D	M	All mutations	M	3.0	>1
506	D	N	All mutations	N	1.0	1
506	D	E	All mutations	E	1.0	1
506	D	R	All mutations	R	2.0	>1
506	D	V	All mutations	V	1.0	1
506	D	W	All mutations	W	3.0	>1
506	D	K	All mutations	K	2.0	>1
506	D	H	All mutations	H	1.0	1
506	D	Y	All mutations	Y	1.0	1
506	D	S	All mutations	S	2.0	>1
506	D	D	All mutations	D	0.0	0
506	D	P	All mutations	P	2.0	>1
506	D	F	All mutations	F	2.0	>1
506	D	I	All mutations	I	2.0	>1
506	D	Q	All mutations	Q	2.0	>1
506	D	C	All mutations	C	2.0	>1
506	D	T	All mutations	T	2.0	>1
507	Q	K	All mutations	K	0.9968573224387178	1
507	Q	N	All mutations	N	1.9968573224387178	>1
507	Q	H	All mutations	H	1.0031426775612822	1
507	Q	T	All mutations	T	1.9968573224387178	>1
507	Q	F	All mutations	F	3.0	>1
507	Q	C	All mutations	C	3.0	>1
507	Q	A	All mutations	A	2.0	>1
507	Q	G	All mutations	G	2.0	>1
507	Q	S	All mutations	S	2.0	>1
507	Q	E	All mutations	E	1.0	1
507	Q	Y	All mutations	Y	2.0	>1
507	Q	L	All mutations	L	1.0031426775612822	1
507	Q	M	All mutations	M	2.4211187932118166	>1
507	Q	P	All mutations	P	1.0031426775612822	1
507	Q	R	All mutations	R	1.0	1
507	Q	D	All mutations	D	2.0	>1
507	Q	Q	All mutations	Q	0.0031426775612822125	1
507	Q	W	All mutations	W	2.4242614707730987	>1
507	Q	I	All mutations	I	2.572595851665619	>1
507	Q	V	All mutations	V	2.0	>1
508	R	K	All mutations	K	1.5091137649277184	>1
508	R	Y	All mutations	Y	2.7919547454431175	>1
508	R	S	All mutations	S	1.7228158390949089	>1
508	R	D	All mutations	D	2.7919547454431175	>1
508	R	G	All mutations	G	1.2086737900691389	>1
508	R	P	All mutations	P	1.282840980515399	>1
508	R	T	All mutations	T	1.717159019484601	>1
508	R	H	All mutations	H	2.074795725958517	>1
508	R	N	All mutations	N	2.509113764927718	>1
508	R	Q	All mutations	Q	1.0747957259585166	1
508	R	L	All mutations	L	1.2822124450031427	>1
508	R	M	All mutations	M	1.993086109365179	>1
508	R	E	All mutations	E	1.7919547454431175	>1
508	R	F	All mutations	F	2.9993714644877434	>1
508	R	W	All mutations	W	1.4852294154619736	>1
508	R	C	All mutations	C	2.208673790069139	>1
508	R	I	All mutations	I	2.4399748585795096	>1
508	R	V	All mutations	V	1.9993714644877436	>1
508	R	R	All mutations	R	0.20867379006913891	1
508	R	A	All mutations	A	2.0	>1
509	G	M	All mutations	M	2.309868007542426	>1
509	G	C	All mutations	C	2.0	>1
509	G	I	All mutations	I	2.690131992457574	>1
509	G	H	All mutations	H	3.0	>1
509	G	V	All mutations	V	1.0	1
509	G	K	All mutations	K	2.0	>1
509	G	F	All mutations	F	3.0	>1
509	G	A	All mutations	A	1.0	1
509	G	G	All mutations	G	0.0	0
509	G	Q	All mutations	Q	2.0	>1
509	G	R	All mutations	R	1.0	1
509	G	P	All mutations	P	2.0	>1
509	G	W	All mutations	W	1.309868007542426	>1
509	G	E	All mutations	E	1.0	1
509	G	L	All mutations	L	2.0	>1
509	G	D	All mutations	D	2.0	>1
509	G	Y	All mutations	Y	3.0	>1
509	G	N	All mutations	N	3.0	>1
509	G	T	All mutations	T	2.0	>1
509	G	S	All mutations	S	2.0	>1
510	N	S	All mutations	S	1.0012570710245128	1
510	N	N	All mutations	N	0.001257071024512885	1
510	N	Q	All mutations	Q	2.0	>1
510	N	P	All mutations	P	2.0	>1
510	N	D	All mutations	D	0.9987429289754871	1
510	N	W	All mutations	W	3.0	>1
510	N	I	All mutations	I	1.0012570710245128	1
510	N	H	All mutations	H	1.0	1
510	N	L	All mutations	L	2.0	>1
510	N	C	All mutations	C	2.0	>1
510	N	V	All mutations	V	1.9987429289754872	>1
510	N	Y	All mutations	Y	1.0	1
510	N	F	All mutations	F	2.0	>1
510	N	G	All mutations	G	1.9987429289754872	>1
510	N	T	All mutations	T	1.0012570710245128	1
510	N	A	All mutations	A	1.9987429289754872	>1
510	N	E	All mutations	E	1.9987429289754872	>1
510	N	M	All mutations	M	2.001257071024513	>1
510	N	R	All mutations	R	2.0	>1
510	N	K	All mutations	K	1.0012570710245128	1
511	V	L	All mutations	L	1.0012570710245128	1
511	V	T	All mutations	T	1.9182903834066625	>1
511	V	M	All mutations	M	1.6360779384035198	>1
511	V	F	All mutations	F	1.993086109365179	>1
511	V	W	All mutations	W	2.7152734129478318	>1
511	V	P	All mutations	P	1.9987429289754872	>1
511	V	D	All mutations	D	2.072281583909491	>1
511	V	K	All mutations	K	1.9277184160905092	>1
511	V	N	All mutations	N	2.9113764927718417	>1
511	V	S	All mutations	S	1.9905719673161533	>1
511	V	Y	All mutations	Y	2.9918290383406663	>1
511	V	H	All mutations	H	2.9918290383406663	>1
511	V	I	All mutations	I	1.2055311125078567	>1
511	V	Q	All mutations	Q	2.0081709616593337	>1
511	V	V	All mutations	V	0.08170961659333752	1
511	V	R	All mutations	R	1.9277184160905092	>1
511	V	C	All mutations	C	2.9918290383406663	>1
511	V	A	All mutations	A	1.0791954745443118	1
511	V	E	All mutations	E	1.0886235072281585	1
511	V	G	All mutations	G	1.0804525455688245	1
512	L	L	All mutations	L	0.0	0
512	L	M	All mutations	M	1.9974858579509742	>1
512	L	Q	All mutations	Q	1.5738529226901319	>1
512	L	T	All mutations	T	2.0	>1
512	L	H	All mutations	H	1.5116279069767442	>1
512	L	N	All mutations	N	2.468887492143306	>1
512	L	G	All mutations	G	2.0	>1
512	L	D	All mutations	D	2.468887492143306	>1
512	L	Y	All mutations	Y	2.426147077309868	>1
512	L	K	All mutations	K	2.531112507856694	>1
512	L	S	All mutations	S	1.957259585166562	>1
512	L	P	All mutations	P	1.042740414833438	1
512	L	R	All mutations	R	1.042740414833438	1
512	L	E	All mutations	E	2.531112507856694	>1
512	L	F	All mutations	F	1.4261470773098681	>1
512	L	A	All mutations	A	2.0	>1
512	L	W	All mutations	W	2.954745443117536	>1
512	L	C	All mutations	C	2.426147077309868	>1
512	L	I	All mutations	I	1.0025141420490258	1
512	L	V	All mutations	V	1.0	1
513	L	I	All mutations	I	1.6499057196731615	>1
513	L	S	All mutations	S	1.305468258956631	>1
513	L	R	All mutations	R	1.694531741043369	>1
513	L	A	All mutations	A	2.0	>1
513	L	E	All mutations	E	2.0006285355122566	>1
513	L	G	All mutations	G	2.0	>1
513	L	V	All mutations	V	1.0	1
513	L	H	All mutations	H	2.6951602765556255	>1
513	L	Q	All mutations	Q	1.6964173475801383	>1
513	L	D	All mutations	D	2.9993714644877434	>1
513	L	C	All mutations	C	2.3048397234443745	>1
513	L	P	All mutations	P	1.695788812067882	>1
513	L	K	All mutations	K	1.9993714644877436	>1
513	L	T	All mutations	T	1.9987429289754872	>1
513	L	Y	All mutations	Y	2.3048397234443745	>1
513	L	F	All mutations	F	1.3048397234443747	>1
513	L	W	All mutations	W	1.6543054682589566	>1
513	L	M	All mutations	M	1.3475801382778128	>1
513	L	L	All mutations	L	0.001257071024512885	1
513	L	N	All mutations	N	2.9981143934632306	>1
514	S	R	All mutations	R	2.0	>1
514	S	P	All mutations	P	1.0	1
514	S	Q	All mutations	Q	2.5461973601508485	>1
514	S	I	All mutations	I	2.0490257699560024	>1
514	S	D	All mutations	D	2.4538026398491515	>1
514	S	N	All mutations	N	2.453174104336895	>1
514	S	S	All mutations	S	0.0006285355122564425	1
514	S	V	All mutations	V	2.0	>1
514	S	E	All mutations	E	2.5461973601508485	>1
514	S	F	All mutations	F	1.4544311753614079	>1
514	S	C	All mutations	C	1.4544311753614079	>1
514	S	Y	All mutations	Y	1.4544311753614079	>1
514	S	K	All mutations	K	2.545568824638592	>1
514	S	A	All mutations	A	1.0	1
514	S	W	All mutations	W	1.9509742300439974	>1
514	S	L	All mutations	L	1.5461973601508485	>1
514	S	T	All mutations	T	0.9993714644877436	1
514	S	G	All mutations	G	2.0	>1
514	S	H	All mutations	H	2.4538026398491515	>1
514	S	M	All mutations	M	2.9497171590194844	>1
515	P	H	All mutations	H	1.0395977372721559	1
515	P	I	All mutations	I	2.0	>1
515	P	Y	All mutations	Y	2.039597737272156	>1
515	P	M	All mutations	M	3.0	>1
515	P	S	All mutations	S	1.0	1
515	P	R	All mutations	R	0.9993714644877436	1
515	P	P	All mutations	P	0.0006285355122564425	1
515	P	K	All mutations	K	2.960402262727844	>1
515	P	W	All mutations	W	2.9993714644877434	>1
515	P	L	All mutations	L	1.0	1
515	P	N	All mutations	N	2.039597737272156	>1
515	P	G	All mutations	G	1.9993714644877436	>1
515	P	Q	All mutations	Q	1.9604022627278441	>1
515	P	A	All mutations	A	1.0006285355122564	1
515	P	V	All mutations	V	2.0	>1
515	P	E	All mutations	E	2.960402262727844	>1
515	P	T	All mutations	T	1.0006285355122564	1
515	P	F	All mutations	F	2.039597737272156	>1
515	P	C	All mutations	C	2.0389692017598993	>1
515	P	D	All mutations	D	2.039597737272156	>1
516	E	F	All mutations	F	3.0	>1
516	E	S	All mutations	S	2.0	>1
516	E	K	All mutations	K	1.0	1
516	E	Q	All mutations	Q	1.0	1
516	E	E	All mutations	E	0.0	0
516	E	C	All mutations	C	3.0	>1
516	E	Y	All mutations	Y	2.0	>1
516	E	R	All mutations	R	2.0	>1
516	E	G	All mutations	G	1.0	1
516	E	W	All mutations	W	2.854179761156505	>1
516	E	P	All mutations	P	2.0	>1
516	E	A	All mutations	A	1.0	1
516	E	L	All mutations	L	2.0	>1
516	E	V	All mutations	V	1.0	1
516	E	H	All mutations	H	2.0	>1
516	E	M	All mutations	M	2.854179761156505	>1
516	E	D	All mutations	D	1.0	1
516	E	N	All mutations	N	2.0	>1
516	E	T	All mutations	T	2.0	>1
516	E	I	All mutations	I	2.145820238843495	>1
517	E	F	All mutations	F	3.0	>1
517	E	K	All mutations	K	1.0	1
517	E	M	All mutations	M	2.587680703959774	>1
517	E	W	All mutations	W	2.587680703959774	>1
517	E	L	All mutations	L	2.0	>1
517	E	R	All mutations	R	2.0	>1
517	E	D	All mutations	D	1.0	1
517	E	P	All mutations	P	2.0	>1
517	E	S	All mutations	S	2.0	>1
517	E	G	All mutations	G	1.0	1
517	E	N	All mutations	N	2.0	>1
517	E	V	All mutations	V	1.0	1
517	E	Q	All mutations	Q	1.0	1
517	E	A	All mutations	A	1.0	1
517	E	E	All mutations	E	0.0	0
517	E	T	All mutations	T	2.0	>1
517	E	H	All mutations	H	2.0	>1
517	E	C	All mutations	C	3.0	>1
517	E	Y	All mutations	Y	2.0	>1
517	E	I	All mutations	I	2.412319296040226	>1
518	V	Q	All mutations	Q	2.97171590194846	>1
518	V	I	All mutations	I	1.0	1
518	V	Y	All mutations	Y	2.02828409805154	>1
518	V	L	All mutations	L	1.0	1
518	V	W	All mutations	W	2.996857322438718	>1
518	V	N	All mutations	N	2.025141420490258	>1
518	V	D	All mutations	D	1.0314267756128221	1
518	V	M	All mutations	M	1.9937146448774357	>1
518	V	P	All mutations	P	2.0	>1
518	V	C	All mutations	C	2.02828409805154	>1
518	V	H	All mutations	H	2.02828409805154	>1
518	V	A	All mutations	A	1.0031426775612822	1
518	V	K	All mutations	K	2.968573224387178	>1
518	V	V	All mutations	V	0.0031426775612822125	1
518	V	F	All mutations	F	1.02828409805154	1
518	V	E	All mutations	E	1.9748585795097422	>1
518	V	S	All mutations	S	1.9968573224387178	>1
518	V	R	All mutations	R	2.0	>1
518	V	G	All mutations	G	1.0031426775612822	1
518	V	T	All mutations	T	1.9968573224387178	>1
519	S	K	All mutations	K	2.0	>1
519	S	G	All mutations	G	1.0	1
519	S	S	All mutations	S	0.0	0
519	S	Y	All mutations	Y	2.0	>1
519	S	A	All mutations	A	2.0	>1
519	S	C	All mutations	C	1.0	1
519	S	V	All mutations	V	2.0	>1
519	S	F	All mutations	F	2.0	>1
519	S	I	All mutations	I	1.0	1
519	S	Q	All mutations	Q	3.0	>1
519	S	W	All mutations	W	2.0	>1
519	S	H	All mutations	H	2.0	>1
519	S	D	All mutations	D	2.0	>1
519	S	M	All mutations	M	2.0	>1
519	S	E	All mutations	E	3.0	>1
519	S	N	All mutations	N	1.0	1
519	S	R	All mutations	R	1.0	1
519	S	P	All mutations	P	2.0	>1
519	S	L	All mutations	L	2.0	>1
519	S	T	All mutations	T	1.0	1
520	E	Q	All mutations	Q	1.0	1
520	E	G	All mutations	G	1.0	1
520	E	N	All mutations	N	2.0	>1
520	E	T	All mutations	T	2.0	>1
520	E	A	All mutations	A	1.0	1
520	E	L	All mutations	L	2.0	>1
520	E	D	All mutations	D	1.0	1
520	E	M	All mutations	M	2.680075424261471	>1
520	E	F	All mutations	F	3.0	>1
520	E	C	All mutations	C	3.0	>1
520	E	V	All mutations	V	1.0	1
520	E	I	All mutations	I	2.319924575738529	>1
520	E	H	All mutations	H	2.0	>1
520	E	E	All mutations	E	0.0	0
520	E	S	All mutations	S	2.0	>1
520	E	K	All mutations	K	1.0	1
520	E	R	All mutations	R	2.0	>1
520	E	P	All mutations	P	2.0	>1
520	E	W	All mutations	W	2.680075424261471	>1
520	E	Y	All mutations	Y	2.0	>1
521	T	R	All mutations	R	1.083595223130107	1
521	T	F	All mutations	F	2.923318667504714	>1
521	T	E	All mutations	E	2.063482086737901	>1
521	T	N	All mutations	N	1.9239472030169704	>1
521	T	W	All mutations	W	2.974230043997486	>1
521	T	G	All mutations	G	1.993086109365179	>1
521	T	Q	All mutations	Q	2.0703959773727214	>1
521	T	K	All mutations	K	1.0773098680075424	1
521	T	L	All mutations	L	2.0	>1
521	T	P	All mutations	P	1.0062853551225643	1
521	T	D	All mutations	D	2.9101194217473285	>1
521	T	H	All mutations	H	2.9170333123821495	>1
521	T	T	All mutations	T	0.013199245757385292	1
521	T	I	All mutations	I	1.032683846637335	1
521	T	S	All mutations	S	1.0043997485857952	1
521	T	A	All mutations	A	0.9993714644877436	1
521	T	Y	All mutations	Y	2.9170333123821495	>1
521	T	V	All mutations	V	1.993086109365179	>1
521	T	C	All mutations	C	2.923318667504714	>1
521	T	M	All mutations	M	1.9811439346323068	>1
522	Q	M	All mutations	M	2.389063482086738	>1
522	Q	E	All mutations	E	1.0917661847894407	1
522	Q	K	All mutations	K	1.0911376492771843	1
522	Q	C	All mutations	C	2.9981143934632306	>1
522	Q	F	All mutations	F	2.907605279698303	>1
522	Q	L	All mutations	L	0.9094908862350722	1
522	Q	P	All mutations	P	1.0018856065367694	1
522	Q	V	All mutations	V	1.9088623507228157	>1
522	Q	W	All mutations	W	2.4789440603394093	>1
522	Q	D	All mutations	D	2.0917661847894404	>1
522	Q	S	All mutations	S	1.9987429289754872	>1
522	Q	N	All mutations	N	2.0911376492771843	>1
522	Q	T	All mutations	T	1.9993714644877436	>1
522	Q	I	All mutations	I	2.427404148334381	>1
522	Q	R	All mutations	R	1.0006285355122564	1
522	Q	H	All mutations	H	1.0936517913262098	1
522	Q	Y	All mutations	Y	2.0905091137649277	>1
522	Q	Q	All mutations	Q	0.09365179132620993	1
522	Q	A	All mutations	A	2.0	>1
522	Q	G	All mutations	G	1.9993714644877436	>1
523	G	C	All mutations	C	1.9949717159019484	>1
523	G	E	All mutations	E	1.0050282840980516	1
523	G	N	All mutations	N	2.9949717159019484	>1
523	G	M	All mutations	M	2.844123192960402	>1
523	G	I	All mutations	I	2.155876807039598	>1
523	G	H	All mutations	H	2.9949717159019484	>1
523	G	V	All mutations	V	1.0	1
523	G	P	All mutations	P	2.0	>1
523	G	L	All mutations	L	2.0	>1
523	G	G	All mutations	G	0.0	0
523	G	R	All mutations	R	1.0	1
523	G	W	All mutations	W	1.8441231929604023	>1
523	G	F	All mutations	F	2.9949717159019484	>1
523	G	T	All mutations	T	2.0	>1
523	G	D	All mutations	D	1.9949717159019484	>1
523	G	Y	All mutations	Y	2.9949717159019484	>1
523	G	Q	All mutations	Q	2.0050282840980516	>1
523	G	A	All mutations	A	1.0	1
523	G	K	All mutations	K	2.0050282840980516	>1
523	G	S	All mutations	S	1.9949717159019484	>1
524	T	H	All mutations	H	2.9905719673161535	>1
524	T	I	All mutations	I	1.26147077309868	>1
524	T	E	All mutations	E	2.003142677561282	>1
524	T	K	All mutations	K	1.0163419233186675	1
524	T	Q	All mutations	Q	2.0094280326838465	>1
524	T	T	All mutations	T	0.016341923318667503	1
524	T	D	All mutations	D	2.984286612193589	>1
524	T	N	All mutations	N	1.9974858579509742	>1
524	T	L	All mutations	L	1.9899434318038969	>1
524	T	C	All mutations	C	2.989943431803897	>1
524	T	M	All mutations	M	1.7335009428032684	>1
524	T	V	All mutations	V	1.984286612193589	>1
524	T	R	All mutations	R	1.0163419233186675	1
524	T	A	All mutations	A	1.0031426775612822	1
524	T	F	All mutations	F	2.9805153991200504	>1
524	T	G	All mutations	G	1.9937146448774357	>1
524	T	S	All mutations	S	1.0087994971715901	1
524	T	W	All mutations	W	2.7353865493400376	>1
524	T	P	All mutations	P	1.0094280326838467	1
524	T	Y	All mutations	Y	2.989943431803897	>1
525	E	I	All mutations	I	2.5845380263984916	>1
525	E	D	All mutations	D	1.0	1
525	E	K	All mutations	K	1.0	1
525	E	T	All mutations	T	2.0	>1
525	E	V	All mutations	V	1.0	1
525	E	W	All mutations	W	2.4154619736015084	>1
525	E	L	All mutations	L	2.0	>1
525	E	R	All mutations	R	2.0	>1
525	E	F	All mutations	F	3.0	>1
525	E	M	All mutations	M	2.4154619736015084	>1
525	E	N	All mutations	N	2.0	>1
525	E	C	All mutations	C	3.0	>1
525	E	H	All mutations	H	2.0	>1
525	E	S	All mutations	S	2.0	>1
525	E	A	All mutations	A	1.0	1
525	E	G	All mutations	G	1.0	1
525	E	Q	All mutations	Q	1.0	1
525	E	P	All mutations	P	2.0	>1
525	E	E	All mutations	E	0.0	0
525	E	Y	All mutations	Y	2.0	>1
526	K	G	All mutations	G	1.9597737272155877	>1
526	K	D	All mutations	D	2.0402262727844125	>1
526	K	R	All mutations	R	0.9597737272155877	1
526	K	L	All mutations	L	2.0	>1
526	K	Q	All mutations	Q	1.0402262727844123	1
526	K	W	All mutations	W	2.5292269013199244	>1
526	K	P	All mutations	P	2.0	>1
526	K	N	All mutations	N	1.0402262727844123	1
526	K	T	All mutations	T	1.0	1
526	K	C	All mutations	C	2.9597737272155875	>1
526	K	I	All mutations	I	1.430546825895663	>1
526	K	F	All mutations	F	3.0	>1
526	K	E	All mutations	E	1.0402262727844123	1
526	K	H	All mutations	H	2.0402262727844125	>1
526	K	M	All mutations	M	1.569453174104337	>1
526	K	V	All mutations	V	2.0	>1
526	K	A	All mutations	A	2.0	>1
526	K	K	All mutations	K	0.04022627278441232	1
526	K	S	All mutations	S	1.9597737272155877	>1
526	K	Y	All mutations	Y	2.0402262727844125	>1
527	L	C	All mutations	C	2.569453174104337	>1
527	L	R	All mutations	R	1.430546825895663	>1
527	L	F	All mutations	F	1.569453174104337	>1
527	L	V	All mutations	V	1.0	1
527	L	A	All mutations	A	2.0	>1
527	L	M	All mutations	M	1.2036455059710873	>1
527	L	Q	All mutations	Q	1.430546825895663	>1
527	L	H	All mutations	H	2.430546825895663	>1
527	L	D	All mutations	D	3.0	>1
527	L	W	All mutations	W	1.7730986800754243	>1
527	L	N	All mutations	N	3.0	>1
527	L	I	All mutations	I	1.7963544940289127	>1
527	L	T	All mutations	T	2.0	>1
527	L	Y	All mutations	Y	2.569453174104337	>1
527	L	P	All mutations	P	1.430546825895663	>1
527	L	G	All mutations	G	2.0	>1
527	L	E	All mutations	E	2.0	>1
527	L	L	All mutations	L	0.0	0
527	L	K	All mutations	K	2.0	>1
527	L	S	All mutations	S	1.569453174104337	>1
528	T	D	All mutations	D	2.8799497171590196	>1
528	T	L	All mutations	L	2.0	>1
528	T	K	All mutations	K	1.1200502828409804	>1
528	T	T	All mutations	T	0.0	0
528	T	I	All mutations	I	1.2664990571967316	>1
528	T	R	All mutations	R	1.1200502828409804	>1
528	T	N	All mutations	N	1.8799497171590196	>1
528	T	E	All mutations	E	2.1200502828409804	>1
528	T	Q	All mutations	Q	2.1200502828409804	>1
528	T	A	All mutations	A	1.0	1
528	T	H	All mutations	H	2.8799497171590196	>1
528	T	P	All mutations	P	1.0	1
528	T	G	All mutations	G	2.0	>1
528	T	S	All mutations	S	1.0	1
528	T	W	All mutations	W	2.733500942803268	>1
528	T	Y	All mutations	Y	2.8799497171590196	>1
528	T	C	All mutations	C	2.8799497171590196	>1
528	T	V	All mutations	V	2.0	>1
528	T	M	All mutations	M	1.7335009428032684	>1
528	T	F	All mutations	F	2.8799497171590196	>1
529	I	H	All mutations	H	2.61659333752357	>1
529	I	G	All mutations	G	1.9949717159019484	>1
529	I	C	All mutations	C	2.61659333752357	>1
529	I	F	All mutations	F	1.6172218730358265	>1
529	I	K	All mutations	K	1.3884349465744814	>1
529	I	Q	All mutations	Q	2.38340666247643	>1
529	I	I	All mutations	I	0.0056568196103079825	1
529	I	Y	All mutations	Y	2.61659333752357	>1
529	I	V	All mutations	V	0.9956002514142049	1
529	I	P	All mutations	P	1.9993714644877436	>1
529	I	E	All mutations	E	2.3783783783783785	>1
529	I	N	All mutations	N	1.6216216216216217	>1
529	I	S	All mutations	S	1.6165933375235702	>1
529	I	M	All mutations	M	1.005656819610308	1
529	I	T	All mutations	T	1.0043997485857952	1
529	I	L	All mutations	L	1.0006285355122564	1
529	I	A	All mutations	A	1.994343180389692	>1
529	I	D	All mutations	D	2.6115650534255184	>1
529	I	R	All mutations	R	1.3884349465744814	>1
529	I	W	All mutations	W	3.0	>1
530	T	E	All mutations	E	2.4990571967316155	>1
530	T	F	All mutations	F	2.4978001257071023	>1
530	T	Y	All mutations	Y	2.4996857322438717	>1
530	T	A	All mutations	A	1.0031426775612822	1
530	T	N	All mutations	N	1.4996857322438717	>1
530	T	T	All mutations	T	0.0031426775612822125	1
530	T	R	All mutations	R	1.4996857322438717	>1
530	T	G	All mutations	G	2.0	>1
530	T	K	All mutations	K	1.4990571967316153	>1
530	T	I	All mutations	I	1.0163419233186675	1
530	T	Q	All mutations	Q	2.4990571967316155	>1
530	T	W	All mutations	W	2.9811439346323065	>1
530	T	H	All mutations	H	2.4996857322438717	>1
530	T	V	All mutations	V	1.9974858579509742	>1
530	T	L	All mutations	L	1.9974858579509742	>1
530	T	P	All mutations	P	1.0031426775612822	1
530	T	D	All mutations	D	2.4996857322438717	>1
530	T	M	All mutations	M	1.978629792583281	>1
530	T	C	All mutations	C	2.5003142677561283	>1
530	T	S	All mutations	S	1.0018856065367694	1
531	Y	C	All mutations	C	1.0	1
531	Y	E	All mutations	E	2.0	>1
531	Y	F	All mutations	F	1.0	1
531	Y	A	All mutations	A	2.0	>1
531	Y	M	All mutations	M	3.0	>1
531	Y	N	All mutations	N	1.0	1
531	Y	P	All mutations	P	2.0	>1
531	Y	Y	All mutations	Y	0.0	0
531	Y	T	All mutations	T	2.0	>1
531	Y	L	All mutations	L	2.0	>1
531	Y	I	All mutations	I	2.0	>1
531	Y	G	All mutations	G	2.0	>1
531	Y	K	All mutations	K	2.0	>1
531	Y	S	All mutations	S	1.0	1
531	Y	H	All mutations	H	1.0	1
531	Y	V	All mutations	V	2.0	>1
531	Y	R	All mutations	R	2.0	>1
531	Y	Q	All mutations	Q	2.0	>1
531	Y	D	All mutations	D	1.0	1
531	Y	W	All mutations	W	2.0	>1
532	S	E	All mutations	E	2.004399748585795	>1
532	S	A	All mutations	A	1.0	1
532	S	M	All mutations	M	2.5285983658076683	>1
532	S	S	All mutations	S	0.0	0
532	S	N	All mutations	N	2.995600251414205	>1
532	S	K	All mutations	K	2.004399748585795	>1
532	S	R	All mutations	R	2.0	>1
532	S	V	All mutations	V	2.0	>1
532	S	H	All mutations	H	2.995600251414205	>1
532	S	P	All mutations	P	1.0	1
532	S	T	All mutations	T	1.0	1
532	S	I	All mutations	I	2.4714016341923317	>1
532	S	Y	All mutations	Y	1.9956002514142048	>1
532	S	D	All mutations	D	2.995600251414205	>1
532	S	W	All mutations	W	1.528598365807668	>1
532	S	Q	All mutations	Q	2.004399748585795	>1
532	S	F	All mutations	F	1.9956002514142048	>1
532	S	G	All mutations	G	2.0	>1
532	S	L	All mutations	L	1.0043997485857952	1
532	S	C	All mutations	C	1.9956002514142048	>1
533	S	K	All mutations	K	2.015713387806411	>1
533	S	Q	All mutations	Q	2.015713387806411	>1
533	S	C	All mutations	C	1.984286612193589	>1
533	S	I	All mutations	I	2.2620993086109364	>1
533	S	A	All mutations	A	1.0	1
533	S	S	All mutations	S	0.0	0
533	S	D	All mutations	D	2.984286612193589	>1
533	S	Y	All mutations	Y	1.984286612193589	>1
533	S	M	All mutations	M	2.7379006913890636	>1
533	S	L	All mutations	L	1.015713387806411	1
533	S	H	All mutations	H	2.984286612193589	>1
533	S	R	All mutations	R	2.0	>1
533	S	F	All mutations	F	1.984286612193589	>1
533	S	P	All mutations	P	1.0	1
533	S	E	All mutations	E	2.015713387806411	>1
533	S	W	All mutations	W	1.7379006913890636	>1
533	S	T	All mutations	T	1.0	1
533	S	V	All mutations	V	2.0	>1
533	S	G	All mutations	G	2.0	>1
533	S	N	All mutations	N	2.984286612193589	>1
534	S	N	All mutations	N	2.654934003771213	>1
534	S	M	All mutations	M	2.996857322438718	>1
534	S	T	All mutations	T	1.0	1
534	S	Y	All mutations	Y	1.6580766813324952	>1
534	S	G	All mutations	G	1.9993714644877436	>1
534	S	E	All mutations	E	2.3444374607165304	>1
534	S	W	All mutations	W	2.0	>1
534	S	D	All mutations	D	2.6543054682589564	>1
534	S	I	All mutations	I	2.003142677561282	>1
534	S	Q	All mutations	Q	2.342551854179761	>1
534	S	A	All mutations	A	0.9993714644877436	1
534	S	P	All mutations	P	0.9974858579509742	1
534	S	L	All mutations	L	1.345065996228787	>1
534	S	V	All mutations	V	1.9993714644877436	>1
534	S	R	All mutations	R	1.9974858579509742	>1
534	S	S	All mutations	S	0.0031426775612822125	1
534	S	K	All mutations	K	2.345065996228787	>1
534	S	C	All mutations	C	1.6580766813324952	>1
534	S	F	All mutations	F	1.6580766813324952	>1
534	S	H	All mutations	H	2.6524198617221875	>1
535	M	G	All mutations	G	2.0	>1
535	M	F	All mutations	F	1.9578881206788183	>1
535	M	A	All mutations	A	2.0	>1
535	M	V	All mutations	V	1.0	1
535	M	C	All mutations	C	2.9578881206788186	>1
535	M	W	All mutations	W	1.9604022627278441	>1
535	M	M	All mutations	M	0.04714016341923319	1
535	M	S	All mutations	S	1.9578881206788183	>1
535	M	Q	All mutations	Q	1.9974858579509742	>1
535	M	N	All mutations	N	2.0446260213702074	>1
535	M	K	All mutations	K	1.0446260213702074	1
535	M	L	All mutations	L	0.9553739786297926	1
535	M	D	All mutations	D	3.0	>1
535	M	R	All mutations	R	1.0421118793211817	1
535	M	H	All mutations	H	2.9974858579509744	>1
535	M	T	All mutations	T	1.0446260213702074	1
535	M	P	All mutations	P	1.9974858579509742	>1
535	M	I	All mutations	I	1.0421118793211817	1
535	M	Y	All mutations	Y	2.9578881206788186	>1
535	M	E	All mutations	E	2.0	>1
536	M	C	All mutations	C	3.0	>1
536	M	E	All mutations	E	2.0	>1
536	M	G	All mutations	G	2.0	>1
536	M	M	All mutations	M	0.0	0
536	M	T	All mutations	T	1.0	1
536	M	Q	All mutations	Q	2.0	>1
536	M	P	All mutations	P	2.0	>1
536	M	I	All mutations	I	1.0	1
536	M	L	All mutations	L	1.0	1
536	M	N	All mutations	N	2.0	>1
536	M	S	All mutations	S	2.0	>1
536	M	H	All mutations	H	3.0	>1
536	M	D	All mutations	D	3.0	>1
536	M	A	All mutations	A	2.0	>1
536	M	R	All mutations	R	1.0	1
536	M	W	All mutations	W	2.0	>1
536	M	Y	All mutations	Y	3.0	>1
536	M	K	All mutations	K	1.0	1
536	M	V	All mutations	V	1.0	1
536	M	F	All mutations	F	2.0	>1
537	W	L	All mutations	L	1.0	1
537	W	E	All mutations	E	2.0	>1
537	W	D	All mutations	D	3.0	>1
537	W	C	All mutations	C	1.0	1
537	W	M	All mutations	M	2.0	>1
537	W	R	All mutations	R	1.0	1
537	W	G	All mutations	G	1.0	1
537	W	K	All mutations	K	2.0	>1
537	W	A	All mutations	A	2.0	>1
537	W	H	All mutations	H	3.0	>1
537	W	S	All mutations	S	1.0	1
537	W	N	All mutations	N	3.0	>1
537	W	V	All mutations	V	2.0	>1
537	W	F	All mutations	F	2.0	>1
537	W	P	All mutations	P	2.0	>1
537	W	Y	All mutations	Y	2.0	>1
537	W	I	All mutations	I	3.0	>1
537	W	W	All mutations	W	0.0	0
537	W	T	All mutations	T	2.0	>1
537	W	Q	All mutations	Q	2.0	>1
538	E	I	All mutations	I	2.589566310496543	>1
538	E	L	All mutations	L	2.0	>1
538	E	M	All mutations	M	2.410433689503457	>1
538	E	Y	All mutations	Y	2.0	>1
538	E	A	All mutations	A	1.0	1
538	E	K	All mutations	K	1.0	1
538	E	W	All mutations	W	2.410433689503457	>1
538	E	F	All mutations	F	3.0	>1
538	E	Q	All mutations	Q	1.0	1
538	E	P	All mutations	P	2.0	>1
538	E	G	All mutations	G	1.0	1
538	E	H	All mutations	H	2.0	>1
538	E	N	All mutations	N	2.0	>1
538	E	S	All mutations	S	2.0	>1
538	E	E	All mutations	E	0.0	0
538	E	T	All mutations	T	2.0	>1
538	E	D	All mutations	D	1.0	1
538	E	V	All mutations	V	1.0	1
538	E	C	All mutations	C	3.0	>1
538	E	R	All mutations	R	2.0	>1
539	I	H	All mutations	H	2.046511627906977	>1
539	I	N	All mutations	N	1.0502828409805154	1
539	I	I	All mutations	I	0.0031426775612822125	1
539	I	T	All mutations	T	1.0031426775612822	1
539	I	D	All mutations	D	2.0446260213702074	>1
539	I	C	All mutations	C	2.047140163419233	>1
539	I	P	All mutations	P	1.9993714644877436	>1
539	I	W	All mutations	W	3.0	>1
539	I	L	All mutations	L	0.9993714644877436	1
539	I	E	All mutations	E	2.950345694531741	>1
539	I	S	All mutations	S	1.0502828409805154	1
539	I	K	All mutations	K	1.956002514142049	>1
539	I	A	All mutations	A	1.9974858579509742	>1
539	I	G	All mutations	G	1.9974858579509742	>1
539	I	Q	All mutations	Q	2.9522313010685104	>1
539	I	Y	All mutations	Y	2.047140163419233	>1
539	I	V	All mutations	V	0.9974858579509742	1
539	I	R	All mutations	R	1.9522313010685104	>1
539	I	F	All mutations	F	1.0471401634192332	1
539	I	M	All mutations	M	1.0031426775612822	1
540	N	S	All mutations	S	0.9993714644877436	1
540	N	T	All mutations	T	1.0	1
540	N	I	All mutations	I	1.0	1
540	N	D	All mutations	D	1.0006285355122564	1
540	N	Y	All mutations	Y	1.0006285355122564	1
540	N	N	All mutations	N	0.0006285355122564425	1
540	N	F	All mutations	F	2.0	>1
540	N	H	All mutations	H	1.0006285355122564	1
540	N	A	All mutations	A	2.0	>1
540	N	R	All mutations	R	1.9993714644877436	>1
540	N	W	All mutations	W	2.9993714644877434	>1
540	N	G	All mutations	G	1.9993714644877436	>1
540	N	L	All mutations	L	2.0	>1
540	N	C	All mutations	C	1.9993714644877436	>1
540	N	Q	All mutations	Q	2.0006285355122566	>1
540	N	E	All mutations	E	2.0006285355122566	>1
540	N	P	All mutations	P	2.0	>1
540	N	K	All mutations	K	1.0006285355122564	1
540	N	V	All mutations	V	2.0	>1
540	N	M	All mutations	M	2.0	>1
541	G	P	All mutations	P	2.0	>1
541	G	S	All mutations	S	1.049654305468259	1
541	G	K	All mutations	K	2.950345694531741	>1
541	G	L	All mutations	L	2.0	>1
541	G	Y	All mutations	Y	2.049654305468259	>1
541	G	E	All mutations	E	1.950345694531741	>1
541	G	T	All mutations	T	2.0	>1
541	G	D	All mutations	D	1.049654305468259	1
541	G	M	All mutations	M	2.9610307982401007	>1
541	G	G	All mutations	G	0.0	0
541	G	I	All mutations	I	2.0389692017598993	>1
541	G	C	All mutations	C	1.049654305468259	1
541	G	A	All mutations	A	1.0	1
541	G	R	All mutations	R	1.0	1
541	G	W	All mutations	W	1.9610307982401005	>1
541	G	H	All mutations	H	2.049654305468259	>1
541	G	Q	All mutations	Q	2.950345694531741	>1
541	G	F	All mutations	F	2.049654305468259	>1
541	G	N	All mutations	N	2.049654305468259	>1
541	G	V	All mutations	V	1.0	1
542	P	R	All mutations	R	0.9993714644877436	1
542	P	Y	All mutations	Y	2.3557510999371463	>1
542	P	A	All mutations	A	1.0006285355122564	1
542	P	W	All mutations	W	2.801382778126964	>1
542	P	D	All mutations	D	2.3557510999371463	>1
542	P	N	All mutations	N	2.3557510999371463	>1
542	P	L	All mutations	L	1.0	1
542	P	H	All mutations	H	1.3557510999371465	>1
542	P	G	All mutations	G	1.9993714644877436	>1
542	P	V	All mutations	V	2.0	>1
542	P	C	All mutations	C	2.35512256442489	>1
542	P	S	All mutations	S	1.0	1
542	P	M	All mutations	M	2.8020113136392206	>1
542	P	E	All mutations	E	2.6442489000628537	>1
542	P	T	All mutations	T	1.0006285355122564	1
542	P	P	All mutations	P	0.0006285355122564425	1
542	P	F	All mutations	F	2.3557510999371463	>1
542	P	Q	All mutations	Q	1.6442489000628535	>1
542	P	I	All mutations	I	2.1979886863607794	>1
542	P	K	All mutations	K	2.6442489000628537	>1
543	E	S	All mutations	S	2.0	>1
543	E	L	All mutations	L	2.0	>1
543	E	W	All mutations	W	2.4934003771213074	>1
543	E	V	All mutations	V	1.0	1
543	E	A	All mutations	A	1.0	1
543	E	M	All mutations	M	2.4934003771213074	>1
543	E	Q	All mutations	Q	1.0006285355122564	1
543	E	E	All mutations	E	0.0006285355122564425	1
543	E	R	All mutations	R	2.0	>1
543	E	H	All mutations	H	1.9993714644877436	>1
543	E	C	All mutations	C	2.9993714644877434	>1
543	E	K	All mutations	K	1.0006285355122564	1
543	E	P	All mutations	P	2.0	>1
543	E	G	All mutations	G	1.0	1
543	E	I	All mutations	I	2.5065996228786926	>1
543	E	T	All mutations	T	2.0	>1
543	E	F	All mutations	F	2.9993714644877434	>1
543	E	Y	All mutations	Y	1.9993714644877436	>1
543	E	D	All mutations	D	0.9993714644877436	1
543	E	N	All mutations	N	1.9993714644877436	>1
544	S	E	All mutations	E	2.0502828409805156	>1
544	S	K	All mutations	K	2.0502828409805156	>1
544	S	L	All mutations	L	1.0502828409805154	1
544	S	F	All mutations	F	1.950345694531741	>1
544	S	W	All mutations	W	1.578252671275927	>1
544	S	D	All mutations	D	2.9497171590194844	>1
544	S	N	All mutations	N	2.9497171590194844	>1
544	S	Q	All mutations	Q	2.049654305468259	>1
544	S	T	All mutations	T	1.0	1
544	S	S	All mutations	S	0.0006285355122564425	1
544	S	A	All mutations	A	1.0	1
544	S	V	All mutations	V	2.0	>1
544	S	G	All mutations	G	2.0	>1
544	S	H	All mutations	H	2.9490886235072282	>1
544	S	Y	All mutations	Y	1.950345694531741	>1
544	S	M	All mutations	M	2.5776241357636707	>1
544	S	P	All mutations	P	0.9993714644877436	1
544	S	C	All mutations	C	1.950345694531741	>1
544	S	I	All mutations	I	2.4223758642363293	>1
544	S	R	All mutations	R	1.9993714644877436	>1
545	V	P	All mutations	P	2.0	>1
545	V	I	All mutations	I	1.8302954116907606	>1
545	V	N	All mutations	N	2.9050911376492774	>1
545	V	F	All mutations	F	1.9050911376492772	>1
545	V	Q	All mutations	Q	2.0949088623507226	>1
545	V	L	All mutations	L	1.0	1
545	V	S	All mutations	S	2.0	>1
545	V	G	All mutations	G	1.0	1
545	V	V	All mutations	V	0.0	0
545	V	E	All mutations	E	1.0949088623507228	1
545	V	M	All mutations	M	1.1697045883092394	>1
545	V	C	All mutations	C	2.9050911376492774	>1
545	V	W	All mutations	W	2.1697045883092394	>1
545	V	A	All mutations	A	1.0	1
545	V	H	All mutations	H	2.9050911376492774	>1
545	V	K	All mutations	K	2.0949088623507226	>1
545	V	D	All mutations	D	1.9050911376492772	>1
545	V	T	All mutations	T	2.0	>1
545	V	R	All mutations	R	2.0	>1
545	V	Y	All mutations	Y	2.9050911376492774	>1
546	L	T	All mutations	T	2.0	>1
546	L	Q	All mutations	Q	1.6002514142049025	>1
546	L	N	All mutations	N	2.903834066624764	>1
546	L	E	All mutations	E	2.096165933375236	>1
546	L	V	All mutations	V	1.0	1
546	L	S	All mutations	S	1.4959145191703331	>1
546	L	F	All mutations	F	1.3997485857950975	>1
546	L	P	All mutations	P	1.5040854808296669	>1
546	L	I	All mutations	I	1.6134506599622878	>1
546	L	C	All mutations	C	2.3997485857950975	>1
546	L	D	All mutations	D	2.903834066624764	>1
546	L	M	All mutations	M	1.3865493400377122	>1
546	L	L	All mutations	L	0.0	0
546	L	K	All mutations	K	2.096165933375236	>1
546	L	Y	All mutations	Y	2.3997485857950975	>1
546	L	G	All mutations	G	2.0	>1
546	L	A	All mutations	A	2.0	>1
546	L	W	All mutations	W	1.8824638592080452	>1
546	L	H	All mutations	H	2.4079195474544313	>1
546	L	R	All mutations	R	1.5040854808296669	>1
547	V	A	All mutations	A	1.005656819610308	1
547	V	K	All mutations	K	2.977372721558768	>1
547	V	G	All mutations	G	1.005656819610308	1
547	V	M	All mutations	M	1.988686360779384	>1
547	V	Q	All mutations	Q	2.9824010056568198	>1
547	V	F	All mutations	F	1.0169704588309239	1
547	V	N	All mutations	N	2.0125707102451287	>1
547	V	D	All mutations	D	1.0232558139534884	1
547	V	W	All mutations	W	2.993086109365179	>1
547	V	Y	All mutations	Y	2.016970458830924	>1
547	V	C	All mutations	C	2.016970458830924	>1
547	V	V	All mutations	V	0.0056568196103079825	1
547	V	E	All mutations	E	1.9880578252671275	>1
547	V	L	All mutations	L	1.0	1
547	V	I	All mutations	I	1.0012570710245128	1
547	V	T	All mutations	T	1.9949717159019484	>1
547	V	S	All mutations	S	1.994343180389692	>1
547	V	H	All mutations	H	2.0175989943431802	>1
547	V	P	All mutations	P	2.0	>1
547	V	R	All mutations	R	2.0	>1
548	N	I	All mutations	I	1.0	1
548	N	T	All mutations	T	1.0	1
548	N	M	All mutations	M	2.0	>1
548	N	Y	All mutations	Y	1.0	1
548	N	Q	All mutations	Q	2.0	>1
548	N	D	All mutations	D	1.0	1
548	N	E	All mutations	E	2.0	>1
548	N	R	All mutations	R	2.0	>1
548	N	N	All mutations	N	0.0	0
548	N	C	All mutations	C	2.0	>1
548	N	W	All mutations	W	3.0	>1
548	N	K	All mutations	K	1.0	1
548	N	A	All mutations	A	2.0	>1
548	N	L	All mutations	L	2.0	>1
548	N	P	All mutations	P	2.0	>1
548	N	V	All mutations	V	2.0	>1
548	N	S	All mutations	S	1.0	1
548	N	G	All mutations	G	2.0	>1
548	N	F	All mutations	F	2.0	>1
548	N	H	All mutations	H	1.0	1
549	T	V	All mutations	V	2.0	>1
549	T	D	All mutations	D	2.3299811439346323	>1
549	T	R	All mutations	R	1.6700188560653677	>1
549	T	W	All mutations	W	2.9981143934632306	>1
549	T	A	All mutations	A	1.0	1
549	T	S	All mutations	S	1.0	1
549	T	E	All mutations	E	2.6700188560653677	>1
549	T	T	All mutations	T	0.0	0
549	T	C	All mutations	C	2.3299811439346323	>1
549	T	L	All mutations	L	2.0	>1
549	T	F	All mutations	F	2.3299811439346323	>1
549	T	P	All mutations	P	1.0	1
549	T	K	All mutations	K	1.6700188560653677	>1
549	T	N	All mutations	N	1.3299811439346323	>1
549	T	G	All mutations	G	2.0	>1
549	T	Q	All mutations	Q	2.6700188560653677	>1
549	T	H	All mutations	H	2.3299811439346323	>1
549	T	Y	All mutations	Y	2.3299811439346323	>1
549	T	M	All mutations	M	1.9981143934632306	>1
549	T	I	All mutations	I	1.0018856065367694	1
550	Y	E	All mutations	E	2.0	>1
550	Y	N	All mutations	N	1.0	1
550	Y	T	All mutations	T	2.0	>1
550	Y	V	All mutations	V	2.0	>1
550	Y	D	All mutations	D	1.0	1
550	Y	I	All mutations	I	2.0	>1
550	Y	P	All mutations	P	2.0	>1
550	Y	A	All mutations	A	2.0	>1
550	Y	Y	All mutations	Y	0.0	0
550	Y	L	All mutations	L	2.0	>1
550	Y	K	All mutations	K	2.0	>1
550	Y	M	All mutations	M	3.0	>1
550	Y	C	All mutations	C	1.0	1
550	Y	Q	All mutations	Q	2.0	>1
550	Y	S	All mutations	S	1.0	1
550	Y	G	All mutations	G	2.0	>1
550	Y	R	All mutations	R	2.0	>1
550	Y	W	All mutations	W	2.0	>1
550	Y	F	All mutations	F	1.0	1
550	Y	H	All mutations	H	1.0	1
551	Q	P	All mutations	P	1.0	1
551	Q	S	All mutations	S	2.0	>1
551	Q	R	All mutations	R	1.0	1
551	Q	C	All mutations	C	3.0	>1
551	Q	A	All mutations	A	2.0	>1
551	Q	L	All mutations	L	1.0	1
551	Q	W	All mutations	W	2.5889377749842866	>1
551	Q	K	All mutations	K	1.0	1
551	Q	G	All mutations	G	2.0	>1
551	Q	Q	All mutations	Q	0.0	0
551	Q	E	All mutations	E	1.0	1
551	Q	Y	All mutations	Y	2.0	>1
551	Q	M	All mutations	M	2.5889377749842866	>1
551	Q	F	All mutations	F	3.0	>1
551	Q	I	All mutations	I	2.4110622250157134	>1
551	Q	D	All mutations	D	2.0	>1
551	Q	V	All mutations	V	2.0	>1
551	Q	H	All mutations	H	1.0	1
551	Q	T	All mutations	T	2.0	>1
551	Q	N	All mutations	N	2.0	>1
552	W	V	All mutations	V	2.0	>1
552	W	G	All mutations	G	1.0	1
552	W	K	All mutations	K	2.0	>1
552	W	W	All mutations	W	0.0	0
552	W	Q	All mutations	Q	2.0	>1
552	W	A	All mutations	A	2.0	>1
552	W	E	All mutations	E	2.0	>1
552	W	C	All mutations	C	1.0	1
552	W	T	All mutations	T	2.0	>1
552	W	S	All mutations	S	1.0	1
552	W	P	All mutations	P	2.0	>1
552	W	M	All mutations	M	2.0	>1
552	W	F	All mutations	F	2.0	>1
552	W	N	All mutations	N	3.0	>1
552	W	Y	All mutations	Y	2.0	>1
552	W	D	All mutations	D	3.0	>1
552	W	H	All mutations	H	3.0	>1
552	W	L	All mutations	L	1.0	1
552	W	I	All mutations	I	3.0	>1
552	W	R	All mutations	R	1.0	1
553	I	D	All mutations	D	2.3324952859836583	>1
553	I	T	All mutations	T	1.0106851037083595	1
553	I	A	All mutations	A	1.9880578252671275	>1
553	I	Q	All mutations	Q	2.656191074795726	>1
553	I	I	All mutations	I	0.013199245757385292	1
553	I	S	All mutations	S	1.3475801382778128	>1
553	I	R	All mutations	R	1.6631049654305468	>1
553	I	Y	All mutations	Y	2.343808925204274	>1
553	I	W	All mutations	W	2.998742928975487	>1
553	I	C	All mutations	C	2.343808925204274	>1
553	I	E	All mutations	E	2.64487743557511	>1
553	I	M	All mutations	M	1.0106851037083595	1
553	I	V	All mutations	V	0.9893148962916405	1
553	I	P	All mutations	P	1.9993714644877436	>1
553	I	G	All mutations	G	1.988686360779384	>1
553	I	L	All mutations	L	1.0006285355122564	1
553	I	N	All mutations	N	1.35512256442489	>1
553	I	F	All mutations	F	1.3444374607165306	>1
553	I	H	All mutations	H	2.343808925204274	>1
553	I	K	All mutations	K	1.667504714016342	>1
554	I	W	All mutations	W	2.9993714644877434	>1
554	I	K	All mutations	K	1.9981143934632306	>1
554	I	Q	All mutations	Q	2.9981143934632306	>1
554	I	R	All mutations	R	1.9974858579509742	>1
554	I	H	All mutations	H	2.0018856065367694	>1
554	I	A	All mutations	A	2.0	>1
554	I	V	All mutations	V	1.0006285355122564	1
554	I	E	All mutations	E	2.9981143934632306	>1
554	I	D	All mutations	D	2.0018856065367694	>1
554	I	L	All mutations	L	1.0006285355122564	1
554	I	P	All mutations	P	2.0	>1
554	I	C	All mutations	C	2.001257071024513	>1
554	I	M	All mutations	M	1.0006285355122564	1
554	I	Y	All mutations	Y	2.0018856065367694	>1
554	I	I	All mutations	I	0.0006285355122564425	1
554	I	S	All mutations	S	1.0012570710245128	1
554	I	T	All mutations	T	1.0	1
554	I	G	All mutations	G	1.9993714644877436	>1
554	I	N	All mutations	N	1.0018856065367694	1
554	I	F	All mutations	F	1.0025141420490258	1
555	R	I	All mutations	I	1.1275927089880577	>1
555	R	M	All mutations	M	1.8837209302325582	>1
555	R	W	All mutations	W	1.8824638592080452	>1
555	R	Y	All mutations	Y	2.996228786926461	>1
555	R	E	All mutations	E	1.9962287869264614	>1
555	R	Q	All mutations	Q	1.9905719673161533	>1
555	R	N	All mutations	N	2.0018856065367694	>1
555	R	R	All mutations	R	0.0043997485857950975	1
555	R	F	All mutations	F	3.0	>1
555	R	G	All mutations	G	1.0043997485857952	1
555	R	C	All mutations	C	2.004399748585795	>1
555	R	L	All mutations	L	1.994343180389692	>1
555	R	V	All mutations	V	2.0	>1
555	R	A	All mutations	A	1.9993714644877436	>1
555	R	S	All mutations	S	1.0094280326838467	1
555	R	K	All mutations	K	1.0018856065367694	1
555	R	T	All mutations	T	1.0050282840980516	1
555	R	H	All mutations	H	2.9905719673161535	>1
555	R	P	All mutations	P	1.9937146448774357	>1
555	R	D	All mutations	D	2.996228786926461	>1
556	N	C	All mutations	C	1.9968573224387178	>1
556	N	H	All mutations	H	1.0031426775612822	1
556	N	E	All mutations	E	2.003142677561282	>1
556	N	A	All mutations	A	2.0	>1
556	N	Y	All mutations	Y	1.0031426775612822	1
556	N	P	All mutations	P	2.0	>1
556	N	S	All mutations	S	0.9968573224387178	1
556	N	D	All mutations	D	1.0031426775612822	1
556	N	F	All mutations	F	2.0	>1
556	N	G	All mutations	G	1.9968573224387178	>1
556	N	L	All mutations	L	2.0	>1
556	N	V	All mutations	V	2.0	>1
556	N	K	All mutations	K	1.0031426775612822	1
556	N	R	All mutations	R	1.9968573224387178	>1
556	N	M	All mutations	M	2.0	>1
556	N	W	All mutations	W	2.996857322438718	>1
556	N	N	All mutations	N	0.0031426775612822125	1
556	N	T	All mutations	T	1.0	1
556	N	Q	All mutations	Q	2.003142677561282	>1
556	N	I	All mutations	I	1.0	1
557	W	I	All mutations	I	3.0	>1
557	W	D	All mutations	D	3.0	>1
557	W	H	All mutations	H	3.0	>1
557	W	R	All mutations	R	1.0	1
557	W	L	All mutations	L	1.0	1
557	W	V	All mutations	V	2.0	>1
557	W	P	All mutations	P	2.0	>1
557	W	M	All mutations	M	2.0	>1
557	W	K	All mutations	K	2.0	>1
557	W	Q	All mutations	Q	2.0	>1
557	W	T	All mutations	T	2.0	>1
557	W	A	All mutations	A	2.0	>1
557	W	C	All mutations	C	1.0	1
557	W	F	All mutations	F	2.0	>1
557	W	N	All mutations	N	3.0	>1
557	W	E	All mutations	E	2.0	>1
557	W	Y	All mutations	Y	2.0	>1
557	W	G	All mutations	G	1.0	1
557	W	S	All mutations	S	1.0	1
557	W	W	All mutations	W	0.0	0
558	E	V	All mutations	V	1.0	1
558	E	G	All mutations	G	1.0	1
558	E	N	All mutations	N	2.0	>1
558	E	T	All mutations	T	2.0	>1
558	E	R	All mutations	R	2.0	>1
558	E	I	All mutations	I	2.2049025769956003	>1
558	E	K	All mutations	K	1.0	1
558	E	S	All mutations	S	2.0	>1
558	E	P	All mutations	P	2.0	>1
558	E	Q	All mutations	Q	1.0	1
558	E	A	All mutations	A	1.0	1
558	E	D	All mutations	D	1.0	1
558	E	E	All mutations	E	0.0	0
558	E	M	All mutations	M	2.7950974230043997	>1
558	E	C	All mutations	C	3.0	>1
558	E	L	All mutations	L	2.0	>1
558	E	H	All mutations	H	2.0	>1
558	E	W	All mutations	W	2.7950974230043997	>1
558	E	F	All mutations	F	3.0	>1
558	E	Y	All mutations	Y	2.0	>1
559	T	R	All mutations	R	1.9120050282840981	>1
559	T	S	All mutations	S	0.9415461973601509	1
559	T	N	All mutations	N	1.0175989943431805	1
559	T	I	All mutations	I	0.9069767441860465	1
559	T	L	All mutations	L	1.8868636077938403	>1
559	T	V	All mutations	V	1.8686360779384035	>1
559	T	F	All mutations	F	1.901948460087995	>1
559	T	P	All mutations	P	1.2023884349465745	>1
559	T	A	All mutations	A	1.1841609050911377	>1
559	T	K	All mutations	K	1.9861722187303583	>1
559	T	D	All mutations	D	1.9805153991200504	>1
559	T	G	All mutations	G	1.9094908862350723	>1
559	T	Q	All mutations	Q	2.967316153362665	>1
559	T	E	All mutations	E	2.9490886235072282	>1
559	T	Y	All mutations	Y	1.9981143934632306	>1
559	T	C	All mutations	C	1.9428032683846637	>1
559	T	T	All mutations	T	0.22124450031426776	1
559	T	H	All mutations	H	1.9987429289754872	>1
559	T	W	All mutations	W	2.92583280955374	>1
559	T	M	All mutations	M	1.9044626021370208	>1
560	V	K	All mutations	K	1.9597737272155877	>1
560	V	M	All mutations	M	1.4173475801382778	>1
560	V	I	All mutations	I	1.4959145191703331	>1
560	V	V	All mutations	V	0.044626021370207415	1
560	V	S	All mutations	S	1.9987429289754872	>1
560	V	Q	All mutations	Q	2.003142677561282	>1
560	V	E	All mutations	E	1.0477686989314896	1
560	V	W	All mutations	W	2.4594594594594597	>1
560	V	Y	All mutations	Y	2.995600251414205	>1
560	V	C	All mutations	C	2.995600251414205	>1
560	V	N	All mutations	N	2.953488372093023	>1
560	V	T	All mutations	T	1.9566310496543056	>1
560	V	L	All mutations	L	0.9987429289754871	1
560	V	P	All mutations	P	2.0	>1
560	V	D	All mutations	D	2.0414833438089253	>1
560	V	G	All mutations	G	1.0446260213702074	1
560	V	H	All mutations	H	2.996857322438718	>1
560	V	R	All mutations	R	1.9566310496543056	>1
560	V	A	All mutations	A	1.0446260213702074	1
560	V	F	All mutations	F	1.9956002514142048	>1
561	K	M	All mutations	M	1.5003142677561283	>1
561	K	D	All mutations	D	2.0	>1
561	K	I	All mutations	I	1.4996857322438717	>1
561	K	V	All mutations	V	2.0	>1
561	K	A	All mutations	A	2.0	>1
561	K	H	All mutations	H	2.0	>1
561	K	E	All mutations	E	1.0	1
561	K	K	All mutations	K	0.0	0
561	K	C	All mutations	C	3.0	>1
561	K	G	All mutations	G	2.0	>1
561	K	F	All mutations	F	3.0	>1
561	K	L	All mutations	L	2.0	>1
561	K	T	All mutations	T	1.0	1
561	K	N	All mutations	N	1.0	1
561	K	Y	All mutations	Y	2.0	>1
561	K	P	All mutations	P	2.0	>1
561	K	R	All mutations	R	1.0	1
561	K	Q	All mutations	Q	1.0	1
561	K	W	All mutations	W	2.5003142677561283	>1
561	K	S	All mutations	S	2.0	>1
562	I	T	All mutations	T	1.0018856065367694	1
562	I	H	All mutations	H	2.001257071024513	>1
562	I	Y	All mutations	Y	2.001257071024513	>1
562	I	G	All mutations	G	1.9981143934632306	>1
562	I	R	All mutations	R	1.9987429289754872	>1
562	I	F	All mutations	F	1.0012570710245128	1
562	I	P	All mutations	P	2.0	>1
562	I	A	All mutations	A	1.9981143934632306	>1
562	I	E	All mutations	E	2.996857322438718	>1
562	I	D	All mutations	D	1.9993714644877436	>1
562	I	C	All mutations	C	2.001257071024513	>1
562	I	L	All mutations	L	1.0	1
562	I	I	All mutations	I	0.00251414204902577	1
562	I	M	All mutations	M	1.0012570710245128	1
562	I	Q	All mutations	Q	2.998742928975487	>1
562	I	W	All mutations	W	2.9993714644877434	>1
562	I	K	All mutations	K	2.0006285355122566	>1
562	I	N	All mutations	N	1.0031426775612822	1
562	I	S	All mutations	S	1.0031426775612822	1
562	I	V	All mutations	V	0.9981143934632307	1
563	Q	Q	All mutations	Q	0.001257071024512885	1
563	Q	A	All mutations	A	2.0	>1
563	Q	V	All mutations	V	2.0	>1
563	Q	R	All mutations	R	0.9993714644877436	1
563	Q	N	All mutations	N	2.0	>1
563	Q	W	All mutations	W	2.8799497171590196	>1
563	Q	F	All mutations	F	2.9993714644877434	>1
563	Q	K	All mutations	K	1.0012570710245128	1
563	Q	M	All mutations	M	2.8805782526712758	>1
563	Q	Y	All mutations	Y	2.0	>1
563	Q	P	All mutations	P	1.0	1
563	Q	C	All mutations	C	2.998742928975487	>1
563	Q	I	All mutations	I	2.1194217473287242	>1
563	Q	D	All mutations	D	2.0	>1
563	Q	T	All mutations	T	2.0	>1
563	Q	S	All mutations	S	2.0	>1
563	Q	H	All mutations	H	1.0	1
563	Q	L	All mutations	L	1.0	1
563	Q	E	All mutations	E	1.0012570710245128	1
563	Q	G	All mutations	G	1.9993714644877436	>1
564	W	G	All mutations	G	1.0	1
564	W	D	All mutations	D	3.0	>1
564	W	H	All mutations	H	3.0	>1
564	W	M	All mutations	M	2.0	>1
564	W	Y	All mutations	Y	2.0	>1
564	W	A	All mutations	A	2.0	>1
564	W	W	All mutations	W	0.0	0
564	W	N	All mutations	N	3.0	>1
564	W	F	All mutations	F	2.0	>1
564	W	Q	All mutations	Q	2.0	>1
564	W	V	All mutations	V	2.0	>1
564	W	S	All mutations	S	1.0	1
564	W	I	All mutations	I	3.0	>1
564	W	P	All mutations	P	2.0	>1
564	W	T	All mutations	T	2.0	>1
564	W	E	All mutations	E	2.0	>1
564	W	L	All mutations	L	1.0	1
564	W	K	All mutations	K	2.0	>1
564	W	R	All mutations	R	1.0	1
564	W	C	All mutations	C	1.0	1
565	S	E	All mutations	E	2.538026398491515	>1
565	S	K	All mutations	K	2.538026398491515	>1
565	S	P	All mutations	P	1.0	1
565	S	I	All mutations	I	2.013827781269642	>1
565	S	Q	All mutations	Q	2.538026398491515	>1
565	S	D	All mutations	D	2.461973601508485	>1
565	S	G	All mutations	G	2.0	>1
565	S	Y	All mutations	Y	1.4619736015084852	>1
565	S	A	All mutations	A	1.0	1
565	S	C	All mutations	C	1.4619736015084852	>1
565	S	M	All mutations	M	2.986172218730358	>1
565	S	W	All mutations	W	1.9861722187303583	>1
565	S	L	All mutations	L	1.5380263984915148	>1
565	S	S	All mutations	S	0.0	0
565	S	R	All mutations	R	2.0	>1
565	S	N	All mutations	N	2.461973601508485	>1
565	S	T	All mutations	T	1.0	1
565	S	F	All mutations	F	1.4619736015084852	>1
565	S	V	All mutations	V	2.0	>1
565	S	H	All mutations	H	2.461973601508485	>1
566	Q	V	All mutations	V	2.0	>1
566	Q	K	All mutations	K	1.0094280326838467	1
566	Q	E	All mutations	E	1.0094280326838467	1
566	Q	S	All mutations	S	2.0	>1
566	Q	N	All mutations	N	1.9905719673161533	>1
566	Q	L	All mutations	L	1.0	1
566	Q	Q	All mutations	Q	0.009428032683846637	1
566	Q	F	All mutations	F	2.9905719673161535	>1
566	Q	A	All mutations	A	2.0	>1
566	Q	W	All mutations	W	2.529855436832181	>1
566	Q	T	All mutations	T	2.0	>1
566	Q	G	All mutations	G	2.0	>1
566	Q	I	All mutations	I	2.470144563167819	>1
566	Q	Y	All mutations	Y	1.9905719673161533	>1
566	Q	D	All mutations	D	1.9905719673161533	>1
566	Q	R	All mutations	R	1.0	1
566	Q	M	All mutations	M	2.529855436832181	>1
566	Q	C	All mutations	C	2.9905719673161535	>1
566	Q	H	All mutations	H	0.9905719673161534	1
566	Q	P	All mutations	P	1.0	1
567	D	Y	All mutations	Y	1.0006285355122564	1
567	D	R	All mutations	R	1.9993714644877436	>1
567	D	V	All mutations	V	1.0025141420490258	1
567	D	Q	All mutations	Q	2.0006285355122566	>1
567	D	P	All mutations	P	2.0	>1
567	D	I	All mutations	I	1.9974858579509742	>1
567	D	S	All mutations	S	1.9968573224387178	>1
567	D	N	All mutations	N	0.9981143934632307	1
567	D	C	All mutations	C	1.9993714644877436	>1
567	D	M	All mutations	M	2.9974858579509744	>1
567	D	G	All mutations	G	1.0018856065367694	1
567	D	L	All mutations	L	2.0	>1
567	D	D	All mutations	D	0.0031426775612822125	1
567	D	E	All mutations	E	1.0031426775612822	1
567	D	T	All mutations	T	1.9974858579509742	>1
567	D	H	All mutations	H	1.0006285355122564	1
567	D	K	All mutations	K	1.9981143934632306	>1
567	D	F	All mutations	F	2.0	>1
567	D	A	All mutations	A	1.0025141420490258	1
567	D	W	All mutations	W	2.9993714644877434	>1
568	P	V	All mutations	V	2.0	>1
568	P	H	All mutations	H	1.0182275298554369	1
568	P	E	All mutations	E	2.981772470144563	>1
568	P	T	All mutations	T	1.0	1
568	P	M	All mutations	M	2.994343180389692	>1
568	P	R	All mutations	R	1.0	1
568	P	I	All mutations	I	2.005656819610308	>1
568	P	C	All mutations	C	2.018227529855437	>1
568	P	Y	All mutations	Y	2.018227529855437	>1
568	P	S	All mutations	S	1.0	1
568	P	A	All mutations	A	1.0	1
568	P	D	All mutations	D	2.018227529855437	>1
568	P	F	All mutations	F	2.018227529855437	>1
568	P	Q	All mutations	Q	1.9817724701445631	>1
568	P	W	All mutations	W	2.994343180389692	>1
568	P	K	All mutations	K	2.981772470144563	>1
568	P	N	All mutations	N	2.018227529855437	>1
568	P	L	All mutations	L	1.0	1
568	P	G	All mutations	G	2.0	>1
568	P	P	All mutations	P	0.0	0
569	T	V	All mutations	V	1.9987429289754872	>1
569	T	E	All mutations	E	2.099308610936518	>1
569	T	T	All mutations	T	0.001257071024512885	1
569	T	M	All mutations	M	1.7567567567567568	>1
569	T	G	All mutations	G	2.0	>1
569	T	P	All mutations	P	1.0012570710245128	1
569	T	K	All mutations	K	1.099308610936518	1
569	T	H	All mutations	H	2.900691389063482	>1
569	T	A	All mutations	A	1.0012570710245128	1
569	T	R	All mutations	R	1.099308610936518	1
569	T	W	All mutations	W	2.75801382778127	>1
569	T	Y	All mutations	Y	2.900691389063482	>1
569	T	F	All mutations	F	2.8994343180389692	>1
569	T	N	All mutations	N	1.900691389063482	>1
569	T	D	All mutations	D	2.900691389063482	>1
569	T	L	All mutations	L	1.9987429289754872	>1
569	T	Q	All mutations	Q	2.099308610936518	>1
569	T	C	All mutations	C	2.900691389063482	>1
569	T	S	All mutations	S	1.0012570710245128	1
569	T	I	All mutations	I	1.2407291011942174	>1
570	M	T	All mutations	T	1.0	1
570	M	A	All mutations	A	2.0	>1
570	M	L	All mutations	L	1.0	1
570	M	S	All mutations	S	1.9541169076052798	>1
570	M	P	All mutations	P	2.0	>1
570	M	W	All mutations	W	2.0691389063482086	>1
570	M	F	All mutations	F	1.9541169076052798	>1
570	M	H	All mutations	H	2.95411690760528	>1
570	M	V	All mutations	V	1.0	1
570	M	Q	All mutations	Q	2.04588309239472	>1
570	M	M	All mutations	M	0.06913890634820867	1
570	M	D	All mutations	D	2.95411690760528	>1
570	M	I	All mutations	I	0.9308610936517914	1
570	M	Y	All mutations	Y	2.95411690760528	>1
570	M	N	All mutations	N	1.9541169076052798	>1
570	M	E	All mutations	E	2.04588309239472	>1
570	M	K	All mutations	K	1.0458830923947202	1
570	M	G	All mutations	G	2.0	>1
570	M	C	All mutations	C	2.95411690760528	>1
570	M	R	All mutations	R	1.0458830923947202	1
571	L	R	All mutations	R	1.6103079824010056	>1
571	L	M	All mutations	M	1.394720301697046	>1
571	L	F	All mutations	F	1.3582652419861723	>1
571	L	W	All mutations	W	1.7850408548082968	>1
571	L	N	All mutations	N	2.9679446888749212	>1
571	L	L	All mutations	L	0.0006285355122564425	1
571	L	A	All mutations	A	1.9993714644877436	>1
571	L	Q	All mutations	Q	1.6423632935260841	>1
571	L	D	All mutations	D	2.967316153362665	>1
571	L	I	All mutations	I	1.605279698302954	>1
571	L	Y	All mutations	Y	2.3582652419861723	>1
571	L	C	All mutations	C	2.3582652419861723	>1
571	L	V	All mutations	V	0.9993714644877436	1
571	L	K	All mutations	K	2.0320553111250788	>1
571	L	P	All mutations	P	1.6103079824010056	>1
571	L	T	All mutations	T	2.0	>1
571	L	G	All mutations	G	1.9993714644877436	>1
571	L	H	All mutations	H	2.5782526712759273	>1
571	L	E	All mutations	E	2.031426775612822	>1
571	L	S	All mutations	S	1.3903205531112508	>1
572	Y	P	All mutations	P	2.0	>1
572	Y	A	All mutations	A	2.0	>1
572	Y	S	All mutations	S	1.0	1
572	Y	Q	All mutations	Q	2.0	>1
572	Y	N	All mutations	N	1.0	1
572	Y	F	All mutations	F	1.0	1
572	Y	C	All mutations	C	1.0	1
572	Y	G	All mutations	G	2.0	>1
572	Y	T	All mutations	T	2.0	>1
572	Y	E	All mutations	E	2.0	>1
572	Y	K	All mutations	K	2.0	>1
572	Y	Y	All mutations	Y	0.0	0
572	Y	M	All mutations	M	3.0	>1
572	Y	V	All mutations	V	2.0	>1
572	Y	H	All mutations	H	1.0	1
572	Y	R	All mutations	R	2.0	>1
572	Y	L	All mutations	L	2.0	>1
572	Y	I	All mutations	I	2.0	>1
572	Y	W	All mutations	W	2.0	>1
572	Y	D	All mutations	D	1.0	1
573	N	L	All mutations	L	2.0	>1
573	N	V	All mutations	V	2.0	>1
573	N	G	All mutations	G	2.0	>1
573	N	C	All mutations	C	2.0	>1
573	N	E	All mutations	E	2.0	>1
573	N	I	All mutations	I	1.0	1
573	N	A	All mutations	A	2.0	>1
573	N	M	All mutations	M	2.0	>1
573	N	Q	All mutations	Q	2.0	>1
573	N	R	All mutations	R	2.0	>1
573	N	D	All mutations	D	1.0	1
573	N	W	All mutations	W	3.0	>1
573	N	H	All mutations	H	1.0	1
573	N	K	All mutations	K	1.0	1
573	N	Y	All mutations	Y	1.0	1
573	N	T	All mutations	T	1.0	1
573	N	N	All mutations	N	0.0	0
573	N	S	All mutations	S	1.0	1
573	N	P	All mutations	P	2.0	>1
573	N	F	All mutations	F	2.0	>1
574	K	F	All mutations	F	3.0	>1
574	K	I	All mutations	I	1.8472658705216844	>1
574	K	P	All mutations	P	2.0	>1
574	K	C	All mutations	C	2.9937146448774357	>1
574	K	Y	All mutations	Y	2.0062853551225643	>1
574	K	G	All mutations	G	1.9937146448774357	>1
574	K	N	All mutations	N	1.0062853551225643	1
574	K	M	All mutations	M	1.1527341294783156	>1
574	K	K	All mutations	K	0.006285355122564425	1
574	K	R	All mutations	R	0.9937146448774355	1
574	K	W	All mutations	W	2.146448774355751	>1
574	K	S	All mutations	S	1.9937146448774357	>1
574	K	A	All mutations	A	2.0	>1
574	K	L	All mutations	L	2.0	>1
574	K	Q	All mutations	Q	1.0062853551225643	1
574	K	T	All mutations	T	1.0	1
574	K	V	All mutations	V	2.0	>1
574	K	H	All mutations	H	2.0062853551225643	>1
574	K	E	All mutations	E	1.0062853551225643	1
574	K	D	All mutations	D	2.0062853551225643	>1
575	M	Y	All mutations	Y	3.0	>1
575	M	T	All mutations	T	1.0930232558139534	1
575	M	N	All mutations	N	2.0930232558139537	>1
575	M	F	All mutations	F	2.0	>1
575	M	S	All mutations	S	2.0	>1
575	M	Q	All mutations	Q	1.9993714644877436	>1
575	M	R	All mutations	R	1.092394720301697	1
575	M	H	All mutations	H	2.9993714644877434	>1
575	M	E	All mutations	E	1.907605279698303	>1
575	M	K	All mutations	K	1.0930232558139534	1
575	M	G	All mutations	G	1.907605279698303	>1
575	M	M	All mutations	M	0.10622250157133878	1
575	M	A	All mutations	A	1.907605279698303	>1
575	M	I	All mutations	I	1.0798240100565681	1
575	M	W	All mutations	W	2.0131992457573853	>1
575	M	C	All mutations	C	3.0	>1
575	M	L	All mutations	L	0.9993714644877436	1
575	M	P	All mutations	P	1.9993714644877436	>1
575	M	D	All mutations	D	2.907605279698303	>1
575	M	V	All mutations	V	0.907605279698303	1
576	E	K	All mutations	K	1.0	1
576	E	I	All mutations	I	2.333752357008171	>1
576	E	P	All mutations	P	2.0	>1
576	E	W	All mutations	W	2.666247642991829	>1
576	E	N	All mutations	N	2.0	>1
576	E	T	All mutations	T	2.0	>1
576	E	Y	All mutations	Y	2.0	>1
576	E	F	All mutations	F	3.0	>1
576	E	D	All mutations	D	1.0	1
576	E	E	All mutations	E	0.0	0
576	E	V	All mutations	V	1.0	1
576	E	M	All mutations	M	2.666247642991829	>1
576	E	A	All mutations	A	1.0	1
576	E	Q	All mutations	Q	1.0	1
576	E	R	All mutations	R	2.0	>1
576	E	C	All mutations	C	3.0	>1
576	E	G	All mutations	G	1.0	1
576	E	L	All mutations	L	2.0	>1
576	E	S	All mutations	S	2.0	>1
576	E	H	All mutations	H	2.0	>1
577	F	L	All mutations	L	1.0	1
577	F	S	All mutations	S	1.0	1
577	F	V	All mutations	V	1.0	1
577	F	H	All mutations	H	2.0	>1
577	F	T	All mutations	T	2.0	>1
577	F	P	All mutations	P	2.0	>1
577	F	A	All mutations	A	2.0	>1
577	F	K	All mutations	K	3.0	>1
577	F	C	All mutations	C	1.0	1
577	F	E	All mutations	E	3.0	>1
577	F	M	All mutations	M	2.0	>1
577	F	I	All mutations	I	1.0	1
577	F	F	All mutations	F	0.0	0
577	F	R	All mutations	R	2.0	>1
577	F	W	All mutations	W	2.0	>1
577	F	Y	All mutations	Y	1.0	1
577	F	D	All mutations	D	2.0	>1
577	F	N	All mutations	N	2.0	>1
577	F	G	All mutations	G	2.0	>1
577	F	Q	All mutations	Q	3.0	>1
578	E	E	All mutations	E	0.0006285355122564425	1
578	E	R	All mutations	R	1.9993714644877436	>1
578	E	D	All mutations	D	1.0006285355122564	1
578	E	N	All mutations	N	2.0006285355122566	>1
578	E	Q	All mutations	Q	1.0006285355122564	1
578	E	Y	All mutations	Y	2.0006285355122566	>1
578	E	F	All mutations	F	3.0	>1
578	E	H	All mutations	H	2.0006285355122566	>1
578	E	T	All mutations	T	2.0	>1
578	E	P	All mutations	P	2.0	>1
578	E	M	All mutations	M	2.3142677561282214	>1
578	E	I	All mutations	I	2.6857322438717786	>1
578	E	L	All mutations	L	2.0	>1
578	E	S	All mutations	S	2.0	>1
578	E	A	All mutations	A	1.0	1
578	E	C	All mutations	C	2.9993714644877434	>1
578	E	K	All mutations	K	1.0006285355122564	1
578	E	V	All mutations	V	1.0	1
578	E	W	All mutations	W	2.313639220615965	>1
578	E	G	All mutations	G	0.9993714644877436	1
579	P	E	All mutations	E	2.3444374607165304	>1
579	P	C	All mutations	C	2.6555625392834696	>1
579	P	V	All mutations	V	2.0	>1
579	P	M	All mutations	M	2.822124450031427	>1
579	P	A	All mutations	A	1.0	1
579	P	L	All mutations	L	1.0	1
579	P	H	All mutations	H	1.6555625392834694	>1
579	P	G	All mutations	G	2.0	>1
579	P	Y	All mutations	Y	2.6555625392834696	>1
579	P	Q	All mutations	Q	1.3444374607165306	>1
579	P	N	All mutations	N	2.6555625392834696	>1
579	P	P	All mutations	P	0.0	0
579	P	I	All mutations	I	2.177875549968573	>1
579	P	K	All mutations	K	2.3444374607165304	>1
579	P	T	All mutations	T	1.0	1
579	P	F	All mutations	F	2.6555625392834696	>1
579	P	S	All mutations	S	1.0	1
579	P	R	All mutations	R	1.0	1
579	P	W	All mutations	W	2.822124450031427	>1
579	P	D	All mutations	D	2.6555625392834696	>1
580	F	D	All mutations	D	2.0	>1
580	F	F	All mutations	F	0.0	0
580	F	G	All mutations	G	2.0	>1
580	F	R	All mutations	R	2.0	>1
580	F	K	All mutations	K	3.0	>1
580	F	M	All mutations	M	2.0	>1
580	F	I	All mutations	I	1.0	1
580	F	L	All mutations	L	1.0	1
580	F	H	All mutations	H	2.0	>1
580	F	C	All mutations	C	1.0	1
580	F	Q	All mutations	Q	3.0	>1
580	F	Y	All mutations	Y	1.0	1
580	F	N	All mutations	N	2.0	>1
580	F	E	All mutations	E	3.0	>1
580	F	T	All mutations	T	2.0	>1
580	F	A	All mutations	A	2.0	>1
580	F	P	All mutations	P	2.0	>1
580	F	V	All mutations	V	1.0	1
580	F	W	All mutations	W	2.0	>1
580	F	S	All mutations	S	1.0	1
581	Q	S	All mutations	S	2.0	>1
581	Q	K	All mutations	K	1.0	1
581	Q	E	All mutations	E	1.0	1
581	Q	M	All mutations	M	2.5260842237586423	>1
581	Q	R	All mutations	R	1.0	1
581	Q	P	All mutations	P	1.0	1
581	Q	T	All mutations	T	2.0	>1
581	Q	N	All mutations	N	2.0	>1
581	Q	Q	All mutations	Q	0.0	0
581	Q	I	All mutations	I	2.4739157762413577	>1
581	Q	W	All mutations	W	2.5260842237586423	>1
581	Q	F	All mutations	F	3.0	>1
581	Q	D	All mutations	D	2.0	>1
581	Q	H	All mutations	H	1.0	1
581	Q	Y	All mutations	Y	2.0	>1
581	Q	L	All mutations	L	1.0	1
581	Q	C	All mutations	C	3.0	>1
581	Q	A	All mutations	A	2.0	>1
581	Q	V	All mutations	V	2.0	>1
581	Q	G	All mutations	G	2.0	>1
582	S	Q	All mutations	Q	2.9974858579509744	>1
582	S	L	All mutations	L	1.9974858579509742	>1
582	S	T	All mutations	T	1.0	1
582	S	A	All mutations	A	0.9981143934632307	1
582	S	G	All mutations	G	1.9981143934632306	>1
582	S	H	All mutations	H	2.0025141420490256	>1
582	S	V	All mutations	V	1.9981143934632306	>1
582	S	I	All mutations	I	2.0006285355122566	>1
582	S	M	All mutations	M	2.9993714644877434	>1
582	S	C	All mutations	C	1.0043997485857952	1
582	S	Y	All mutations	Y	1.0043997485857952	1
582	S	K	All mutations	K	2.9974858579509744	>1
582	S	R	All mutations	R	2.0	>1
582	S	W	All mutations	W	2.001257071024513	>1
582	S	P	All mutations	P	1.0	1
582	S	F	All mutations	F	1.0043997485857952	1
582	S	S	All mutations	S	0.0018856065367693275	1
582	S	E	All mutations	E	2.995600251414205	>1
582	S	N	All mutations	N	2.0025141420490256	>1
582	S	D	All mutations	D	2.0006285355122566	>1
583	L	H	All mutations	H	2.4010056568196103	>1
583	L	T	All mutations	T	2.0	>1
583	L	C	All mutations	C	2.5801382778126962	>1
583	L	D	All mutations	D	2.9905719673161535	>1
583	L	Q	All mutations	Q	1.4198617221873036	>1
583	L	P	All mutations	P	1.410433689503457	>1
583	L	K	All mutations	K	2.0094280326838465	>1
583	L	Y	All mutations	Y	2.5801382778126962	>1
583	L	F	All mutations	F	1.5801382778126964	>1
583	L	I	All mutations	I	1.8189817724701445	>1
583	L	N	All mutations	N	2.9905719673161535	>1
583	L	M	All mutations	M	1.1810182275298555	>1
583	L	E	All mutations	E	2.0094280326838465	>1
583	L	G	All mutations	G	2.0	>1
583	L	W	All mutations	W	1.7705845380263985	>1
583	L	A	All mutations	A	2.0	>1
583	L	S	All mutations	S	1.589566310496543	>1
583	L	R	All mutations	R	1.410433689503457	>1
583	L	V	All mutations	V	1.0	1
583	L	L	All mutations	L	0.0	0
584	V	H	All mutations	H	2.5449402891263357	>1
584	V	C	All mutations	C	2.544311753614079	>1
584	V	E	All mutations	E	1.4745443117536141	>1
584	V	P	All mutations	P	2.0	>1
584	V	F	All mutations	F	1.5443117536140791	>1
584	V	D	All mutations	D	1.5644248900062854	>1
584	V	S	All mutations	S	1.984286612193589	>1
584	V	V	All mutations	V	0.01948460087994972	1
584	V	I	All mutations	I	1.2375864236329353	>1
584	V	N	All mutations	N	2.5260842237586423	>1
584	V	R	All mutations	R	1.9962287869264614	>1
584	V	T	All mutations	T	1.9811439346323068	>1
584	V	L	All mutations	L	0.9993714644877436	1
584	V	G	All mutations	G	1.0194846008799496	1
584	V	Q	All mutations	Q	2.4550597108736643	>1
584	V	W	All mutations	W	2.742928975487115	>1
584	V	K	All mutations	K	2.4362036455059712	>1
584	V	M	All mutations	M	1.7247014456316783	>1
584	V	Y	All mutations	Y	2.544311753614079	>1
584	V	A	All mutations	A	1.0194846008799496	1
585	P	W	All mutations	W	2.9993714644877434	>1
585	P	I	All mutations	I	2.0	>1
585	P	S	All mutations	S	0.9993714644877436	1
585	P	H	All mutations	H	1.0006285355122564	1
585	P	L	All mutations	L	1.0006285355122564	1
585	P	D	All mutations	D	2.0	>1
585	P	T	All mutations	T	1.0	1
585	P	G	All mutations	G	2.0	>1
585	P	M	All mutations	M	3.0	>1
585	P	R	All mutations	R	1.0006285355122564	1
585	P	C	All mutations	C	1.9993714644877436	>1
585	P	A	All mutations	A	1.0	1
585	P	F	All mutations	F	1.9993714644877436	>1
585	P	Y	All mutations	Y	1.9993714644877436	>1
585	P	P	All mutations	P	0.0006285355122564425	1
585	P	Q	All mutations	Q	2.0006285355122566	>1
585	P	V	All mutations	V	2.0	>1
585	P	N	All mutations	N	2.0	>1
585	P	K	All mutations	K	3.0	>1
585	P	E	All mutations	E	3.0	>1
586	K	L	All mutations	L	2.0	>1
586	K	G	All mutations	G	1.9912005028284099	>1
586	K	K	All mutations	K	0.008799497171590195	1
586	K	C	All mutations	C	2.9912005028284097	>1
586	K	D	All mutations	D	2.0087994971715903	>1
586	K	M	All mutations	M	1.4512884978001257	>1
586	K	W	All mutations	W	2.4424890006285356	>1
586	K	R	All mutations	R	0.9912005028284098	1
586	K	A	All mutations	A	2.0	>1
586	K	P	All mutations	P	2.0	>1
586	K	Y	All mutations	Y	2.0087994971715903	>1
586	K	F	All mutations	F	3.0	>1
586	K	I	All mutations	I	1.5487115021998743	>1
586	K	E	All mutations	E	1.0087994971715901	1
586	K	V	All mutations	V	2.0	>1
586	K	S	All mutations	S	1.9912005028284099	>1
586	K	H	All mutations	H	2.0087994971715903	>1
586	K	N	All mutations	N	1.0087994971715901	1
586	K	T	All mutations	T	1.0	1
586	K	Q	All mutations	Q	1.0087994971715901	1
587	A	G	All mutations	G	1.0	1
587	A	Q	All mutations	Q	2.539912005028284	>1
587	A	Y	All mutations	Y	2.460087994971716	>1
587	A	S	All mutations	S	1.0	1
587	A	A	All mutations	A	0.0	0
587	A	I	All mutations	I	2.0081709616593337	>1
587	A	L	All mutations	L	2.0	>1
587	A	M	All mutations	M	2.9918290383406663	>1
587	A	R	All mutations	R	2.0	>1
587	A	H	All mutations	H	2.460087994971716	>1
587	A	N	All mutations	N	2.460087994971716	>1
587	A	C	All mutations	C	2.460087994971716	>1
587	A	V	All mutations	V	1.0	1
587	A	T	All mutations	T	1.0	1
587	A	W	All mutations	W	2.9918290383406663	>1
587	A	P	All mutations	P	1.0	1
587	A	D	All mutations	D	1.4600879949717158	>1
587	A	E	All mutations	E	1.5399120050282842	>1
587	A	K	All mutations	K	2.539912005028284	>1
587	A	F	All mutations	F	2.460087994971716	>1
588	A	D	All mutations	D	1.0861093651791327	1
588	A	C	All mutations	C	2.0219987429289756	>1
588	A	H	All mutations	H	2.0219987429289756	>1
588	A	W	All mutations	W	2.9993714644877434	>1
588	A	T	All mutations	T	1.0546825895663106	1
588	A	I	All mutations	I	1.8177247014456317	>1
588	A	P	All mutations	P	1.1187932118164676	>1
588	A	S	All mutations	S	1.1181646763042112	>1
588	A	A	All mutations	A	0.18290383406662478	1
588	A	Q	All mutations	Q	2.9780012570710244	>1
588	A	Y	All mutations	Y	2.0219987429289756	>1
588	A	E	All mutations	E	2.0421118793211814	>1
588	A	F	All mutations	F	1.9032055311125078	>1
588	A	V	All mutations	V	0.9453174104336896	1
588	A	M	All mutations	M	2.8164676304211187	>1
588	A	K	All mutations	K	2.9138906348208673	>1
588	A	R	All mutations	R	1.9993714644877436	>1
588	A	G	All mutations	G	1.064110622250157	1
588	A	L	All mutations	L	1.8812067881835324	>1
588	A	N	All mutations	N	1.9578881206788183	>1
589	R	K	All mutations	K	1.0119421747328725	1
589	R	W	All mutations	W	1.9321181646763042	>1
589	R	D	All mutations	D	3.0	>1
589	R	S	All mutations	S	1.0119421747328725	1
589	R	A	All mutations	A	2.0	>1
589	R	Q	All mutations	Q	1.9880578252671275	>1
589	R	G	All mutations	G	1.0	1
589	R	Y	All mutations	Y	3.0	>1
589	R	L	All mutations	L	1.9880578252671275	>1
589	R	C	All mutations	C	2.0	>1
589	R	V	All mutations	V	2.0	>1
589	R	N	All mutations	N	2.0119421747328725	>1
589	R	F	All mutations	F	3.0	>1
589	R	I	All mutations	I	1.0798240100565681	1
589	R	P	All mutations	P	1.9880578252671275	>1
589	R	M	All mutations	M	1.9440603394091767	>1
589	R	H	All mutations	H	2.9880578252671275	>1
589	R	R	All mutations	R	0.0	0
589	R	T	All mutations	T	1.0119421747328725	1
589	R	E	All mutations	E	2.0	>1
590	G	V	All mutations	V	1.0062853551225643	1
590	G	C	All mutations	C	1.0289126335637964	1
590	G	Y	All mutations	Y	2.0276555625392834	>1
590	G	D	All mutations	D	1.0345694531741043	1
590	G	A	All mutations	A	1.0050282840980516	1
590	G	G	All mutations	G	0.00754242614707731	1
590	G	E	All mutations	E	1.9780012570710246	>1
590	G	S	All mutations	S	1.022627278441232	1
590	G	P	All mutations	P	1.9987429289754872	>1
590	G	I	All mutations	I	2.013827781269642	>1
590	G	R	All mutations	R	1.0012570710245128	1
590	G	K	All mutations	K	2.9660590823381523	>1
590	G	M	All mutations	M	2.974858579509742	>1
590	G	F	All mutations	F	2.0276555625392834	>1
590	G	N	All mutations	N	2.022627278441232	>1
590	G	L	All mutations	L	2.0	>1
590	G	Q	All mutations	Q	2.97171590194846	>1
590	G	H	All mutations	H	2.02828409805154	>1
590	G	T	All mutations	T	1.993086109365179	>1
590	G	W	All mutations	W	1.9811439346323068	>1
591	Q	F	All mutations	F	2.998742928975487	>1
591	Q	R	All mutations	R	0.9968573224387178	1
591	Q	A	All mutations	A	1.9981143934632306	>1
591	Q	Y	All mutations	Y	2.003771213073539	>1
591	Q	D	All mutations	D	2.003771213073539	>1
591	Q	Q	All mutations	Q	0.00754242614707731	1
591	Q	K	All mutations	K	1.0050282840980516	1
591	Q	S	All mutations	S	1.9981143934632306	>1
591	Q	G	All mutations	G	1.9968573224387178	>1
591	Q	L	All mutations	L	1.0012570710245128	1
591	Q	M	All mutations	M	2.800754242614708	>1
591	Q	W	All mutations	W	2.7988686360779385	>1
591	Q	V	All mutations	V	2.0	>1
591	Q	P	All mutations	P	0.9993714644877436	1
591	Q	I	All mutations	I	2.1967316153362666	>1
591	Q	H	All mutations	H	1.0050282840980516	1
591	Q	T	All mutations	T	1.9968573224387178	>1
591	Q	E	All mutations	E	1.0062853551225643	1
591	Q	N	All mutations	N	2.0025141420490256	>1
591	Q	C	All mutations	C	2.995600251414205	>1
592	Y	N	All mutations	N	1.0	1
592	Y	S	All mutations	S	1.0	1
592	Y	E	All mutations	E	2.0	>1
592	Y	Q	All mutations	Q	2.0	>1
592	Y	D	All mutations	D	1.0	1
592	Y	A	All mutations	A	2.0	>1
592	Y	H	All mutations	H	1.0	1
592	Y	L	All mutations	L	2.0	>1
592	Y	C	All mutations	C	1.0	1
592	Y	F	All mutations	F	1.0	1
592	Y	M	All mutations	M	3.0	>1
592	Y	V	All mutations	V	2.0	>1
592	Y	R	All mutations	R	2.0	>1
592	Y	P	All mutations	P	2.0	>1
592	Y	Y	All mutations	Y	0.0	0
592	Y	I	All mutations	I	2.0	>1
592	Y	K	All mutations	K	2.0	>1
592	Y	W	All mutations	W	2.0	>1
592	Y	T	All mutations	T	2.0	>1
592	Y	G	All mutations	G	2.0	>1
593	S	M	All mutations	M	2.0	>1
593	S	R	All mutations	R	1.0	1
593	S	N	All mutations	N	1.0	1
593	S	P	All mutations	P	2.0	>1
593	S	C	All mutations	C	1.0	1
593	S	S	All mutations	S	0.0	0
593	S	V	All mutations	V	2.0	>1
593	S	D	All mutations	D	2.0	>1
593	S	A	All mutations	A	2.0	>1
593	S	W	All mutations	W	2.0	>1
593	S	H	All mutations	H	2.0	>1
593	S	I	All mutations	I	1.0	1
593	S	K	All mutations	K	2.0	>1
593	S	F	All mutations	F	2.0	>1
593	S	L	All mutations	L	2.0	>1
593	S	Q	All mutations	Q	3.0	>1
593	S	T	All mutations	T	1.0	1
593	S	Y	All mutations	Y	2.0	>1
593	S	E	All mutations	E	3.0	>1
593	S	G	All mutations	G	1.0	1
594	G	M	All mutations	M	2.5260842237586423	>1
594	G	N	All mutations	N	2.9522313010685104	>1
594	G	R	All mutations	R	1.0	1
594	G	K	All mutations	K	2.0477686989314896	>1
594	G	S	All mutations	S	1.9522313010685104	>1
594	G	E	All mutations	E	1.0477686989314896	1
594	G	I	All mutations	I	2.4739157762413577	>1
594	G	P	All mutations	P	2.0	>1
594	G	H	All mutations	H	2.9522313010685104	>1
594	G	F	All mutations	F	2.9522313010685104	>1
594	G	T	All mutations	T	2.0	>1
594	G	W	All mutations	W	1.5260842237586423	>1
594	G	Q	All mutations	Q	2.0477686989314896	>1
594	G	L	All mutations	L	2.0	>1
594	G	Y	All mutations	Y	2.9522313010685104	>1
594	G	A	All mutations	A	1.0	1
594	G	D	All mutations	D	1.9522313010685104	>1
594	G	C	All mutations	C	1.9522313010685104	>1
594	G	G	All mutations	G	0.0	0
594	G	V	All mutations	V	1.0	1
595	F	P	All mutations	P	2.0	>1
595	F	A	All mutations	A	2.0	>1
595	F	K	All mutations	K	3.0	>1
595	F	R	All mutations	R	2.0	>1
595	F	N	All mutations	N	2.0	>1
595	F	H	All mutations	H	2.0	>1
595	F	Q	All mutations	Q	3.0	>1
595	F	D	All mutations	D	2.0	>1
595	F	F	All mutations	F	0.0	0
595	F	Y	All mutations	Y	1.0	1
595	F	V	All mutations	V	1.0	1
595	F	G	All mutations	G	2.0	>1
595	F	T	All mutations	T	2.0	>1
595	F	C	All mutations	C	1.0	1
595	F	M	All mutations	M	2.0	>1
595	F	E	All mutations	E	3.0	>1
595	F	S	All mutations	S	1.0	1
595	F	L	All mutations	L	1.0	1
595	F	W	All mutations	W	2.0	>1
595	F	I	All mutations	I	1.0	1
596	V	D	All mutations	D	1.9912005028284099	>1
596	V	S	All mutations	S	2.0	>1
596	V	F	All mutations	F	1.9899434318038969	>1
596	V	L	All mutations	L	1.0	1
596	V	N	All mutations	N	2.988686360779384	>1
596	V	K	All mutations	K	2.0087994971715903	>1
596	V	T	All mutations	T	1.9987429289754872	>1
596	V	C	All mutations	C	2.989943431803897	>1
596	V	A	All mutations	A	1.0012570710245128	1
596	V	Q	All mutations	Q	2.010056568196103	>1
596	V	E	All mutations	E	1.011313639220616	1
596	V	P	All mutations	P	2.0	>1
596	V	I	All mutations	I	1.8133249528598365	>1
596	V	G	All mutations	G	1.0012570710245128	1
596	V	H	All mutations	H	2.989943431803897	>1
596	V	R	All mutations	R	1.9987429289754872	>1
596	V	M	All mutations	M	1.1841609050911377	>1
596	V	V	All mutations	V	0.001257071024512885	1
596	V	Y	All mutations	Y	2.989943431803897	>1
596	V	W	All mutations	W	2.1854179761156507	>1
597	R	P	All mutations	P	1.9987429289754872	>1
597	R	L	All mutations	L	1.9987429289754872	>1
597	R	Y	All mutations	Y	3.0	>1
597	R	S	All mutations	S	1.0012570710245128	1
597	R	F	All mutations	F	3.0	>1
597	R	T	All mutations	T	1.0012570710245128	1
597	R	M	All mutations	M	1.3306096794468887	>1
597	R	V	All mutations	V	2.0	>1
597	R	C	All mutations	C	2.0	>1
597	R	W	All mutations	W	1.329352608422376	>1
597	R	I	All mutations	I	1.671904462602137	>1
597	R	A	All mutations	A	2.0	>1
597	R	N	All mutations	N	2.001257071024513	>1
597	R	Q	All mutations	Q	1.9987429289754872	>1
597	R	D	All mutations	D	3.0	>1
597	R	H	All mutations	H	2.998742928975487	>1
597	R	G	All mutations	G	1.0	1
597	R	E	All mutations	E	2.0	>1
597	R	R	All mutations	R	0.0	0
597	R	K	All mutations	K	1.0012570710245128	1
598	T	E	All mutations	E	2.0106851037083597	>1
598	T	G	All mutations	G	1.9120050282840981	>1
598	T	M	All mutations	M	1.8830923947203018	>1
598	T	H	All mutations	H	2.9013199245757386	>1
598	T	V	All mutations	V	1.818353236957888	>1
598	T	K	All mutations	K	1.1866750471401635	>1
598	T	T	All mutations	T	0.1816467630421119	1
598	T	F	All mutations	F	2.807668133249529	>1
598	T	S	All mutations	S	1.0905091137649277	1
598	T	Q	All mutations	Q	2.0986800754242614	>1
598	T	W	All mutations	W	2.8887492143306095	>1
598	T	R	All mutations	R	1.0999371464487744	1
598	T	D	All mutations	D	2.8133249528598365	>1
598	T	L	All mutations	L	1.9063482086737902	>1
598	T	C	All mutations	C	2.9013199245757386	>1
598	T	P	All mutations	P	1.0936517913262098	1
598	T	A	All mutations	A	1.005656819610308	1
598	T	I	All mutations	I	1.1055939660590823	>1
598	T	N	All mutations	N	1.9893148962916405	>1
598	T	Y	All mutations	Y	2.9013199245757386	>1
599	L	M	All mutations	M	1.8070395977372722	>1
599	L	L	All mutations	L	0.0006285355122564425	1
599	L	F	All mutations	F	1.8120678818353237	>1
599	L	D	All mutations	D	2.9993714644877434	>1
599	L	A	All mutations	A	1.9993714644877436	>1
599	L	P	All mutations	P	1.1885606536769326	>1
599	L	W	All mutations	W	2.619107479572596	>1
599	L	S	All mutations	S	1.8120678818353237	>1
599	L	N	All mutations	N	3.0	>1
599	L	E	All mutations	E	1.9993714644877436	>1
599	L	I	All mutations	I	1.1929604022627278	>1
599	L	Q	All mutations	Q	1.1885606536769326	>1
599	L	K	All mutations	K	2.0	>1
599	L	H	All mutations	H	2.188560653676933	>1
599	L	Y	All mutations	Y	2.8120678818353237	>1
599	L	T	All mutations	T	2.0	>1
599	L	V	All mutations	V	0.9993714644877436	1
599	L	R	All mutations	R	1.1885606536769326	>1
599	L	G	All mutations	G	1.9993714644877436	>1
599	L	C	All mutations	C	2.8120678818353237	>1
600	F	A	All mutations	A	2.0	>1
600	F	C	All mutations	C	1.0	1
600	F	F	All mutations	F	0.0	0
600	F	K	All mutations	K	3.0	>1
600	F	N	All mutations	N	2.0	>1
600	F	H	All mutations	H	2.0	>1
600	F	D	All mutations	D	2.0	>1
600	F	G	All mutations	G	2.0	>1
600	F	I	All mutations	I	1.0	1
600	F	P	All mutations	P	2.0	>1
600	F	Q	All mutations	Q	3.0	>1
600	F	R	All mutations	R	2.0	>1
600	F	W	All mutations	W	2.0	>1
600	F	M	All mutations	M	2.0	>1
600	F	L	All mutations	L	1.0	1
600	F	Y	All mutations	Y	1.0	1
600	F	V	All mutations	V	1.0	1
600	F	T	All mutations	T	2.0	>1
600	F	S	All mutations	S	1.0	1
600	F	E	All mutations	E	3.0	>1
601	Q	T	All mutations	T	2.0	>1
601	Q	I	All mutations	I	2.732872407291012	>1
601	Q	W	All mutations	W	2.267127592708988	>1
601	Q	S	All mutations	S	2.0	>1
601	Q	F	All mutations	F	3.0	>1
601	Q	M	All mutations	M	2.267127592708988	>1
601	Q	A	All mutations	A	2.0	>1
601	Q	N	All mutations	N	2.0	>1
601	Q	H	All mutations	H	1.0	1
601	Q	G	All mutations	G	2.0	>1
601	Q	R	All mutations	R	1.0	1
601	Q	K	All mutations	K	1.0	1
601	Q	P	All mutations	P	1.0	1
601	Q	V	All mutations	V	2.0	>1
601	Q	C	All mutations	C	3.0	>1
601	Q	Q	All mutations	Q	0.0	0
601	Q	Y	All mutations	Y	2.0	>1
601	Q	D	All mutations	D	2.0	>1
601	Q	L	All mutations	L	1.0	1
601	Q	E	All mutations	E	1.0	1
602	Q	V	All mutations	V	2.0	>1
602	Q	R	All mutations	R	1.0	1
602	Q	Y	All mutations	Y	2.0	>1
602	Q	P	All mutations	P	1.0	1
602	Q	T	All mutations	T	2.0	>1
602	Q	I	All mutations	I	2.399120050282841	>1
602	Q	D	All mutations	D	2.0	>1
602	Q	S	All mutations	S	2.0	>1
602	Q	G	All mutations	G	2.0	>1
602	Q	M	All mutations	M	2.600879949717159	>1
602	Q	E	All mutations	E	1.0	1
602	Q	N	All mutations	N	2.0	>1
602	Q	Q	All mutations	Q	0.0	0
602	Q	F	All mutations	F	3.0	>1
602	Q	H	All mutations	H	1.0	1
602	Q	C	All mutations	C	3.0	>1
602	Q	L	All mutations	L	1.0	1
602	Q	W	All mutations	W	2.600879949717159	>1
602	Q	A	All mutations	A	2.0	>1
602	Q	K	All mutations	K	1.0	1
603	M	H	All mutations	H	3.0	>1
603	M	G	All mutations	G	2.0	>1
603	M	A	All mutations	A	2.0	>1
603	M	W	All mutations	W	2.0	>1
603	M	R	All mutations	R	1.0	1
603	M	D	All mutations	D	3.0	>1
603	M	K	All mutations	K	1.0	1
603	M	M	All mutations	M	0.0	0
603	M	C	All mutations	C	3.0	>1
603	M	Y	All mutations	Y	3.0	>1
603	M	E	All mutations	E	2.0	>1
603	M	N	All mutations	N	2.0	>1
603	M	T	All mutations	T	1.0	1
603	M	I	All mutations	I	1.0	1
603	M	P	All mutations	P	2.0	>1
603	M	L	All mutations	L	1.0	1
603	M	S	All mutations	S	2.0	>1
603	M	F	All mutations	F	2.0	>1
603	M	V	All mutations	V	1.0	1
603	M	Q	All mutations	Q	2.0	>1
604	R	F	All mutations	F	2.464487743557511	>1
604	R	S	All mutations	S	1.4424890006285356	>1
604	R	Y	All mutations	Y	2.464487743557511	>1
604	R	Q	All mutations	Q	1.5575109993714644	>1
604	R	N	All mutations	N	2.4424890006285356	>1
604	R	K	All mutations	K	2.5135135135135136	>1
604	R	D	All mutations	D	2.464487743557511	>1
604	R	T	All mutations	T	1.9780012570710246	>1
604	R	G	All mutations	G	1.0	1
604	R	C	All mutations	C	1.464487743557511	>1
604	R	E	All mutations	E	2.535512256442489	>1
604	R	W	All mutations	W	1.8969201759899434	>1
604	R	A	All mutations	A	2.0	>1
604	R	I	All mutations	I	2.081081081081081	>1
604	R	R	All mutations	R	0.0	0
604	R	V	All mutations	V	2.0	>1
604	R	M	All mutations	M	2.874921433060968	>1
604	R	L	All mutations	L	1.0219987429289754	1
604	R	P	All mutations	P	1.0219987429289754	1
604	R	H	All mutations	H	1.4864864864864864	>1
605	D	E	All mutations	E	1.0	1
605	D	P	All mutations	P	2.0	>1
605	D	C	All mutations	C	2.0	>1
605	D	T	All mutations	T	2.0	>1
605	D	W	All mutations	W	3.0	>1
605	D	D	All mutations	D	0.0	0
605	D	K	All mutations	K	2.0	>1
605	D	A	All mutations	A	1.0	1
605	D	N	All mutations	N	1.0	1
605	D	Q	All mutations	Q	2.0	>1
605	D	M	All mutations	M	3.0	>1
605	D	L	All mutations	L	2.0	>1
605	D	Y	All mutations	Y	1.0	1
605	D	S	All mutations	S	2.0	>1
605	D	G	All mutations	G	1.0	1
605	D	F	All mutations	F	2.0	>1
605	D	V	All mutations	V	1.0	1
605	D	H	All mutations	H	1.0	1
605	D	R	All mutations	R	2.0	>1
605	D	I	All mutations	I	2.0	>1
606	V	F	All mutations	F	1.987429289754871	>1
606	V	G	All mutations	G	1.0012570710245128	1
606	V	D	All mutations	D	1.988686360779384	>1
606	V	P	All mutations	P	2.0	>1
606	V	A	All mutations	A	1.0012570710245128	1
606	V	T	All mutations	T	1.9987429289754872	>1
606	V	V	All mutations	V	0.001257071024512885	1
606	V	H	All mutations	H	2.9874292897548713	>1
606	V	L	All mutations	L	1.0	1
606	V	W	All mutations	W	2.3463230672532998	>1
606	V	K	All mutations	K	2.011313639220616	>1
606	V	N	All mutations	N	2.986172218730358	>1
606	V	Y	All mutations	Y	2.9874292897548713	>1
606	V	M	All mutations	M	1.345065996228787	>1
606	V	S	All mutations	S	2.0	>1
606	V	I	All mutations	I	1.6524198617221872	>1
606	V	Q	All mutations	Q	2.0125707102451287	>1
606	V	R	All mutations	R	1.9987429289754872	>1
606	V	C	All mutations	C	2.9874292897548713	>1
606	V	E	All mutations	E	1.0138277812696417	1
607	L	S	All mutations	S	1.868007542426147	>1
607	L	D	All mutations	D	2.544311753614079	>1
607	L	E	All mutations	E	2.455688246385921	>1
607	L	Y	All mutations	Y	2.413576367064739	>1
607	L	Q	All mutations	Q	1.5876807039597738	>1
607	L	C	All mutations	C	2.413576367064739	>1
607	L	N	All mutations	N	2.5430546825895664	>1
607	L	L	All mutations	L	0.001257071024512885	1
607	L	I	All mutations	I	1.4236329352608423	>1
607	L	P	All mutations	P	1.131992457573853	>1
607	L	T	All mutations	T	1.9987429289754872	>1
607	L	V	All mutations	V	1.0	1
607	L	G	All mutations	G	2.0	>1
607	L	R	All mutations	R	1.131992457573853	>1
607	L	K	All mutations	K	2.454431175361408	>1
607	L	W	All mutations	W	2.444374607165305	>1
607	L	H	All mutations	H	1.676304211187932	>1
607	L	A	All mutations	A	2.0	>1
607	L	F	All mutations	F	1.4135763670647392	>1
607	L	M	All mutations	M	1.5738529226901319	>1
608	G	W	All mutations	W	1.52294154619736	>1
608	G	E	All mutations	E	1.0	1
608	G	N	All mutations	N	3.0	>1
608	G	Y	All mutations	Y	3.0	>1
608	G	D	All mutations	D	2.0	>1
608	G	K	All mutations	K	2.0	>1
608	G	S	All mutations	S	2.0	>1
608	G	M	All mutations	M	2.52294154619736	>1
608	G	Q	All mutations	Q	2.0	>1
608	G	C	All mutations	C	2.0	>1
608	G	H	All mutations	H	3.0	>1
608	G	G	All mutations	G	0.0	0
608	G	I	All mutations	I	2.47705845380264	>1
608	G	R	All mutations	R	1.0	1
608	G	A	All mutations	A	1.0	1
608	G	L	All mutations	L	2.0	>1
608	G	F	All mutations	F	3.0	>1
608	G	T	All mutations	T	2.0	>1
608	G	P	All mutations	P	2.0	>1
608	G	V	All mutations	V	1.0	1
609	T	M	All mutations	M	1.9352608422375863	>1
609	T	D	All mutations	D	2.953488372093023	>1
609	T	S	All mutations	S	1.0	1
609	T	G	All mutations	G	2.0	>1
609	T	P	All mutations	P	1.0	1
609	T	C	All mutations	C	2.953488372093023	>1
609	T	E	All mutations	E	2.046511627906977	>1
609	T	F	All mutations	F	2.953488372093023	>1
609	T	Q	All mutations	Q	2.046511627906977	>1
609	T	R	All mutations	R	1.0465116279069768	1
609	T	L	All mutations	L	2.0	>1
609	T	H	All mutations	H	2.953488372093023	>1
609	T	T	All mutations	T	0.0	0
609	T	W	All mutations	W	2.9352608422375863	>1
609	T	K	All mutations	K	1.0465116279069768	1
609	T	V	All mutations	V	2.0	>1
609	T	N	All mutations	N	1.9534883720930232	>1
609	T	Y	All mutations	Y	2.953488372093023	>1
609	T	I	All mutations	I	1.0647391577624137	1
609	T	A	All mutations	A	1.0	1
610	F	C	All mutations	C	1.0006285355122564	1
610	F	G	All mutations	G	2.0	>1
610	F	Q	All mutations	Q	2.9993714644877434	>1
610	F	I	All mutations	I	1.0	1
610	F	Y	All mutations	Y	1.0006285355122564	1
610	F	K	All mutations	K	3.0	>1
610	F	W	All mutations	W	2.0006285355122566	>1
610	F	S	All mutations	S	1.0006285355122564	1
610	F	M	All mutations	M	2.0	>1
610	F	F	All mutations	F	0.0006285355122564425	1
610	F	T	All mutations	T	2.0	>1
610	F	H	All mutations	H	1.9993714644877436	>1
610	F	P	All mutations	P	1.9993714644877436	>1
610	F	E	All mutations	E	3.0	>1
610	F	D	All mutations	D	2.0	>1
610	F	R	All mutations	R	1.9993714644877436	>1
610	F	L	All mutations	L	0.9993714644877436	1
610	F	V	All mutations	V	1.0	1
610	F	A	All mutations	A	2.0	>1
610	F	N	All mutations	N	2.0	>1
611	D	A	All mutations	A	1.0018856065367694	1
611	D	R	All mutations	R	2.0	>1
611	D	I	All mutations	I	1.9987429289754872	>1
611	D	G	All mutations	G	1.0018856065367694	1
611	D	E	All mutations	E	1.0018856065367694	1
611	D	T	All mutations	T	1.9987429289754872	>1
611	D	H	All mutations	H	1.0	1
611	D	Y	All mutations	Y	0.9993714644877436	1
611	D	N	All mutations	N	0.9987429289754871	1
611	D	V	All mutations	V	1.0018856065367694	1
611	D	P	All mutations	P	2.0	>1
611	D	C	All mutations	C	1.9993714644877436	>1
611	D	L	All mutations	L	2.0	>1
611	D	W	All mutations	W	2.9993714644877434	>1
611	D	M	All mutations	M	2.998742928975487	>1
611	D	F	All mutations	F	1.9993714644877436	>1
611	D	D	All mutations	D	0.0018856065367693275	1
611	D	S	All mutations	S	1.9981143934632306	>1
611	D	Q	All mutations	Q	2.0	>1
611	D	K	All mutations	K	1.9987429289754872	>1
612	T	A	All mutations	A	1.0	1
612	T	F	All mutations	F	2.043997485857951	>1
612	T	M	All mutations	M	1.9767441860465116	>1
612	T	W	All mutations	W	2.975487115021999	>1
612	T	P	All mutations	P	1.0	1
612	T	D	All mutations	D	2.0446260213702074	>1
612	T	C	All mutations	C	2.043997485857951	>1
612	T	H	All mutations	H	2.0446260213702074	>1
612	T	I	All mutations	I	1.0245128849780012	1
612	T	T	All mutations	T	0.0006285355122564425	1
612	T	N	All mutations	N	1.0452545568824638	1
612	T	Q	All mutations	Q	2.9553739786297926	>1
612	T	G	All mutations	G	2.0	>1
612	T	Y	All mutations	Y	2.043997485857951	>1
612	T	K	All mutations	K	1.956002514142049	>1
612	T	E	All mutations	E	2.9553739786297926	>1
612	T	L	All mutations	L	2.0	>1
612	T	V	All mutations	V	2.0	>1
612	T	R	All mutations	R	1.9553739786297926	>1
612	T	S	All mutations	S	0.9993714644877436	1
613	V	I	All mutations	I	0.9239472030169704	1
613	V	L	All mutations	L	1.027027027027027	1
613	V	M	All mutations	M	1.9226901319924576	>1
613	V	A	All mutations	A	1.076681332495286	1
613	V	E	All mutations	E	2.0986800754242614	>1
613	V	Y	All mutations	Y	2.0050282840980516	>1
613	V	H	All mutations	H	2.0050282840980516	>1
613	V	K	All mutations	K	2.8912633563796355	>1
613	V	F	All mutations	F	1.0320553111250785	1
613	V	W	All mutations	W	2.9993714644877434	>1
613	V	D	All mutations	D	1.1087366436203645	>1
613	V	S	All mutations	S	1.8692646134506599	>1
613	V	R	All mutations	R	2.0	>1
613	V	T	All mutations	T	1.8692646134506599	>1
613	V	C	All mutations	C	2.0050282840980516	>1
613	V	P	All mutations	P	1.972972972972973	>1
613	V	V	All mutations	V	0.13073538654934003	1
613	V	Q	All mutations	Q	2.9949717159019484	>1
613	V	N	All mutations	N	1.9013199245757386	>1
613	V	G	All mutations	G	1.103708359522313	>1
614	Q	Q	All mutations	Q	0.0	0
614	Q	D	All mutations	D	2.0	>1
614	Q	L	All mutations	L	1.0	1
614	Q	S	All mutations	S	2.0	>1
614	Q	T	All mutations	T	2.0	>1
614	Q	K	All mutations	K	1.0	1
614	Q	G	All mutations	G	2.0	>1
614	Q	M	All mutations	M	2.391577624135764	>1
614	Q	E	All mutations	E	1.0	1
614	Q	C	All mutations	C	3.0	>1
614	Q	V	All mutations	V	2.0	>1
614	Q	Y	All mutations	Y	2.0	>1
614	Q	H	All mutations	H	1.0	1
614	Q	I	All mutations	I	2.608422375864236	>1
614	Q	F	All mutations	F	3.0	>1
614	Q	P	All mutations	P	1.0	1
614	Q	A	All mutations	A	2.0	>1
614	Q	R	All mutations	R	1.0	1
614	Q	N	All mutations	N	2.0	>1
614	Q	W	All mutations	W	2.391577624135764	>1
615	I	D	All mutations	D	2.993086109365179	>1
615	I	Q	All mutations	Q	2.0062853551225643	>1
615	I	L	All mutations	L	1.0	1
615	I	P	All mutations	P	2.0	>1
615	I	K	All mutations	K	1.006913890634821	1
615	I	F	All mutations	F	1.9937146448774357	>1
615	I	S	All mutations	S	1.9937146448774357	>1
615	I	I	All mutations	I	0.0006285355122564425	1
615	I	M	All mutations	M	1.0006285355122564	1
615	I	N	All mutations	N	1.994343180389692	>1
615	I	T	All mutations	T	1.0006285355122564	1
615	I	W	All mutations	W	3.0	>1
615	I	V	All mutations	V	0.9993714644877436	1
615	I	A	All mutations	A	1.9993714644877436	>1
615	I	R	All mutations	R	1.006913890634821	1
615	I	C	All mutations	C	2.9937146448774357	>1
615	I	E	All mutations	E	2.005656819610308	>1
615	I	G	All mutations	G	1.9993714644877436	>1
615	I	Y	All mutations	Y	2.9937146448774357	>1
615	I	H	All mutations	H	2.9937146448774357	>1
616	I	P	All mutations	P	2.0	>1
616	I	M	All mutations	M	1.0012570710245128	1
616	I	S	All mutations	S	1.9830295411690761	>1
616	I	T	All mutations	T	1.0025141420490258	1
616	I	E	All mutations	E	2.014456316781898	>1
616	I	V	All mutations	V	0.9974858579509742	1
616	I	R	All mutations	R	1.0194846008799496	1
616	I	F	All mutations	F	1.9830295411690761	>1
616	I	G	All mutations	G	1.9974858579509742	>1
616	I	N	All mutations	N	1.985543683218102	>1
616	I	I	All mutations	I	0.003771213073538655	1
616	I	H	All mutations	H	2.983029541169076	>1
616	I	C	All mutations	C	2.983029541169076	>1
616	I	W	All mutations	W	2.998742928975487	>1
616	I	L	All mutations	L	1.0	1
616	I	Q	All mutations	Q	2.016970458830924	>1
616	I	A	All mutations	A	1.9974858579509742	>1
616	I	D	All mutations	D	2.9805153991200504	>1
616	I	Y	All mutations	Y	2.983029541169076	>1
616	I	K	All mutations	K	1.0194846008799496	1
617	K	S	All mutations	S	2.0	>1
617	K	Q	All mutations	Q	1.0	1
617	K	W	All mutations	W	2.545568824638592	>1
617	K	M	All mutations	M	1.5455688246385921	>1
617	K	H	All mutations	H	2.0	>1
617	K	P	All mutations	P	2.0	>1
617	K	R	All mutations	R	1.0	1
617	K	T	All mutations	T	1.0	1
617	K	I	All mutations	I	1.4544311753614079	>1
617	K	D	All mutations	D	2.0	>1
617	K	Y	All mutations	Y	2.0	>1
617	K	K	All mutations	K	0.0	0
617	K	L	All mutations	L	2.0	>1
617	K	C	All mutations	C	3.0	>1
617	K	F	All mutations	F	3.0	>1
617	K	N	All mutations	N	1.0	1
617	K	E	All mutations	E	1.0	1
617	K	A	All mutations	A	2.0	>1
617	K	G	All mutations	G	2.0	>1
617	K	V	All mutations	V	2.0	>1
618	L	F	All mutations	F	1.4632306725329982	>1
618	L	P	All mutations	P	1.0238843494657448	1
618	L	D	All mutations	D	2.487115021998743	>1
618	L	W	All mutations	W	2.6700188560653677	>1
618	L	C	All mutations	C	2.463230672532998	>1
618	L	T	All mutations	T	2.0	>1
618	L	A	All mutations	A	2.0	>1
618	L	H	All mutations	H	1.5109993714644878	>1
618	L	S	All mutations	S	1.9761156505342552	>1
618	L	N	All mutations	N	2.487115021998743	>1
618	L	G	All mutations	G	2.0	>1
618	L	E	All mutations	E	2.512884978001257	>1
618	L	M	All mutations	M	1.6939032055311125	>1
618	L	I	All mutations	I	1.3060967944688875	>1
618	L	Y	All mutations	Y	2.463230672532998	>1
618	L	Q	All mutations	Q	1.5367693274670018	>1
618	L	K	All mutations	K	2.512884978001257	>1
618	L	R	All mutations	R	1.0238843494657448	1
618	L	L	All mutations	L	0.0	0
618	L	V	All mutations	V	1.0	1
619	L	V	All mutations	V	1.0	1
619	L	R	All mutations	R	1.2042740414833437	>1
619	L	E	All mutations	E	2.4186046511627906	>1
619	L	H	All mutations	H	1.786926461345066	>1
619	L	F	All mutations	F	1.3771213073538655	>1
619	L	N	All mutations	N	2.5801382778126962	>1
619	L	D	All mutations	D	2.5813953488372094	>1
619	L	L	All mutations	L	0.001257071024512885	1
619	L	T	All mutations	T	1.9987429289754872	>1
619	L	A	All mutations	A	2.0	>1
619	L	P	All mutations	P	1.2055311125078567	>1
619	L	G	All mutations	G	2.0	>1
619	L	M	All mutations	M	1.956002514142049	>1
619	L	S	All mutations	S	1.7957259585166563	>1
619	L	Y	All mutations	Y	2.3771213073538653	>1
619	L	K	All mutations	K	2.4173475801382778	>1
619	L	W	All mutations	W	2.7529855436832182	>1
619	L	Q	All mutations	Q	1.6241357636706475	>1
619	L	I	All mutations	I	1.0414833438089253	1
619	L	C	All mutations	C	2.3771213073538653	>1
620	P	C	All mutations	C	2.5518541797611567	>1
620	P	K	All mutations	K	2.4468887492143305	>1
620	P	G	All mutations	G	2.0	>1
620	P	A	All mutations	A	1.0	1
620	P	D	All mutations	D	2.5531112507856695	>1
620	P	F	All mutations	F	2.5518541797611567	>1
620	P	S	All mutations	S	0.9987429289754871	1
620	P	Y	All mutations	Y	2.5518541797611567	>1
620	P	E	All mutations	E	2.4468887492143305	>1
620	P	H	All mutations	H	1.5543683218101823	>1
620	P	L	All mutations	L	1.0	1
620	P	Q	All mutations	Q	1.4481458202388435	>1
620	P	R	All mutations	R	1.0012570710245128	1
620	P	N	All mutations	N	2.5531112507856695	>1
620	P	P	All mutations	P	0.001257071024512885	1
620	P	I	All mutations	I	2.1200502828409804	>1
620	P	T	All mutations	T	1.0	1
620	P	M	All mutations	M	2.8799497171590196	>1
620	P	W	All mutations	W	2.878692646134507	>1
620	P	V	All mutations	V	2.0	>1
621	F	L	All mutations	L	1.0	1
621	F	P	All mutations	P	2.0	>1
621	F	S	All mutations	S	1.0	1
621	F	F	All mutations	F	0.0	0
621	F	I	All mutations	I	1.0	1
621	F	G	All mutations	G	2.0	>1
621	F	C	All mutations	C	1.0	1
621	F	D	All mutations	D	2.0	>1
621	F	Q	All mutations	Q	3.0	>1
621	F	K	All mutations	K	3.0	>1
621	F	Y	All mutations	Y	1.0	1
621	F	E	All mutations	E	3.0	>1
621	F	H	All mutations	H	2.0	>1
621	F	R	All mutations	R	2.0	>1
621	F	N	All mutations	N	2.0	>1
621	F	T	All mutations	T	2.0	>1
621	F	M	All mutations	M	2.0	>1
621	F	W	All mutations	W	2.0	>1
621	F	V	All mutations	V	1.0	1
621	F	A	All mutations	A	2.0	>1
622	A	V	All mutations	V	1.0006285355122564	1
622	A	Y	All mutations	Y	2.538026398491515	>1
622	A	R	All mutations	R	1.9993714644877436	>1
622	A	I	All mutations	I	2.0094280326838465	>1
622	A	T	All mutations	T	0.9993714644877436	1
622	A	N	All mutations	N	2.537397862979258	>1
622	A	A	All mutations	A	0.0006285355122564425	1
622	A	W	All mutations	W	2.989943431803897	>1
622	A	M	All mutations	M	2.9893148962916403	>1
622	A	G	All mutations	G	1.0006285355122564	1
622	A	F	All mutations	F	2.538026398491515	>1
622	A	D	All mutations	D	1.5386549340037712	>1
622	A	Q	All mutations	Q	2.461973601508485	>1
622	A	K	All mutations	K	2.4613450659962286	>1
622	A	C	All mutations	C	2.538026398491515	>1
622	A	L	All mutations	L	2.0	>1
622	A	E	All mutations	E	1.4626021370207416	>1
622	A	P	All mutations	P	1.0	1
622	A	H	All mutations	H	2.538026398491515	>1
622	A	S	All mutations	S	1.0	1
623	A	A	All mutations	A	0.0006285355122564425	1
623	A	E	All mutations	E	1.4651162790697674	>1
623	A	H	All mutations	H	2.535512256442489	>1
623	A	Y	All mutations	Y	2.5348837209302326	>1
623	A	C	All mutations	C	2.5348837209302326	>1
623	A	V	All mutations	V	1.0006285355122564	1
623	A	R	All mutations	R	2.0	>1
623	A	F	All mutations	F	2.5348837209302326	>1
623	A	S	All mutations	S	0.9993714644877436	1
623	A	L	All mutations	L	1.9993714644877436	>1
623	A	P	All mutations	P	1.0	1
623	A	T	All mutations	T	1.0	1
623	A	I	All mutations	I	2.001257071024513	>1
623	A	Q	All mutations	Q	2.464487743557511	>1
623	A	G	All mutations	G	1.0006285355122564	1
623	A	N	All mutations	N	2.535512256442489	>1
623	A	W	All mutations	W	2.9981143934632306	>1
623	A	D	All mutations	D	1.5361407919547454	>1
623	A	M	All mutations	M	2.998742928975487	>1
623	A	K	All mutations	K	2.464487743557511	>1
624	A	K	All mutations	K	2.829038340666248	>1
624	A	Q	All mutations	Q	2.829038340666248	>1
624	A	V	All mutations	V	1.0006285355122564	1
624	A	G	All mutations	G	1.0006285355122564	1
624	A	D	All mutations	D	1.1715901948460088	>1
624	A	Y	All mutations	Y	2.170333123821496	>1
624	A	F	All mutations	F	2.170333123821496	>1
624	A	A	All mutations	A	0.0006285355122564425	1
624	A	M	All mutations	M	2.993086109365179	>1
624	A	W	All mutations	W	2.992457573852923	>1
624	A	E	All mutations	E	1.829666876178504	>1
624	A	N	All mutations	N	2.170961659333752	>1
624	A	T	All mutations	T	1.0	1
624	A	L	All mutations	L	2.0	>1
624	A	H	All mutations	H	2.170961659333752	>1
624	A	P	All mutations	P	1.0	1
624	A	I	All mutations	I	2.006913890634821	>1
624	A	C	All mutations	C	2.170333123821496	>1
624	A	S	All mutations	S	0.9993714644877436	1
624	A	R	All mutations	R	2.0	>1
625	P	V	All mutations	V	2.0	>1
625	P	I	All mutations	I	2.0905091137649277	>1
625	P	C	All mutations	C	2.993086109365179	>1
625	P	S	All mutations	S	0.9993714644877436	1
625	P	T	All mutations	T	1.0	1
625	P	P	All mutations	P	0.0006285355122564425	1
625	P	F	All mutations	F	2.993086109365179	>1
625	P	K	All mutations	K	2.0062853551225643	>1
625	P	D	All mutations	D	2.9937146448774357	>1
625	P	N	All mutations	N	2.9937146448774357	>1
625	P	A	All mutations	A	1.0	1
625	P	R	All mutations	R	1.0006285355122564	1
625	P	H	All mutations	H	1.994343180389692	>1
625	P	E	All mutations	E	2.0062853551225643	>1
625	P	M	All mutations	M	2.9094908862350723	>1
625	P	Y	All mutations	Y	2.993086109365179	>1
625	P	G	All mutations	G	2.0	>1
625	P	L	All mutations	L	1.0	1
625	P	Q	All mutations	Q	1.006913890634821	1
625	P	W	All mutations	W	2.9088623507228157	>1
626	P	R	All mutations	R	1.0	1
626	P	C	All mutations	C	2.922061596480201	>1
626	P	N	All mutations	N	2.922061596480201	>1
626	P	T	All mutations	T	1.0	1
626	P	P	All mutations	P	0.0	0
626	P	I	All mutations	I	2.636706473915776	>1
626	P	H	All mutations	H	1.922061596480201	>1
626	P	L	All mutations	L	1.0	1
626	P	G	All mutations	G	2.0	>1
626	P	V	All mutations	V	2.0	>1
626	P	Q	All mutations	Q	1.077938403519799	1
626	P	S	All mutations	S	1.0	1
626	P	E	All mutations	E	2.077938403519799	>1
626	P	M	All mutations	M	2.363293526084224	>1
626	P	F	All mutations	F	2.922061596480201	>1
626	P	A	All mutations	A	1.0	1
626	P	K	All mutations	K	2.077938403519799	>1
626	P	D	All mutations	D	2.922061596480201	>1
626	P	W	All mutations	W	2.363293526084224	>1
626	P	Y	All mutations	Y	2.922061596480201	>1
627	E	N	All mutations	N	1.9924575738529227	>1
627	E	Y	All mutations	Y	2.0006285355122566	>1
627	E	H	All mutations	H	2.0006285355122566	>1
627	E	T	All mutations	T	1.9918290383406663	>1
627	E	C	All mutations	C	3.0	>1
627	E	W	All mutations	W	2.686989314896292	>1
627	E	M	All mutations	M	2.6781898177247014	>1
627	E	P	All mutations	P	2.0	>1
627	E	D	All mutations	D	1.0087994971715901	1
627	E	L	All mutations	L	1.9993714644877436	>1
627	E	F	All mutations	F	2.9993714644877434	>1
627	E	E	All mutations	E	0.008799497171590195	1
627	E	G	All mutations	G	1.0081709616593337	1
627	E	V	All mutations	V	1.0075424261470773	1
627	E	R	All mutations	R	1.9918290383406663	>1
627	E	I	All mutations	I	2.3042111879321183	>1
627	E	Q	All mutations	Q	1.0006285355122564	1
627	E	S	All mutations	S	2.0	>1
627	E	K	All mutations	K	0.9924575738529227	1
627	E	A	All mutations	A	1.0081709616593337	1
628	Q	I	All mutations	I	2.338152105593966	>1
628	Q	G	All mutations	G	2.0	>1
628	Q	N	All mutations	N	1.9082338152105593	>1
628	Q	H	All mutations	H	0.9094908862350722	1
628	Q	K	All mutations	K	1.0905091137649277	1
628	Q	F	All mutations	F	2.9088623507228157	>1
628	Q	W	All mutations	W	2.6612193588937774	>1
628	Q	E	All mutations	E	1.0911376492771843	1
628	Q	P	All mutations	P	1.0006285355122564	1
628	Q	Y	All mutations	Y	1.9088623507228157	>1
628	Q	D	All mutations	D	1.9088623507228157	>1
628	Q	M	All mutations	M	2.660590823381521	>1
628	Q	T	All mutations	T	1.9993714644877436	>1
628	Q	A	All mutations	A	2.0	>1
628	Q	Q	All mutations	Q	0.0917661847894406	1
628	Q	V	All mutations	V	2.0	>1
628	Q	R	All mutations	R	1.0	1
628	Q	S	All mutations	S	2.0	>1
628	Q	L	All mutations	L	1.0006285355122564	1
628	Q	C	All mutations	C	2.9088623507228157	>1
629	S	P	All mutations	P	1.9987429289754872	>1
629	S	F	All mutations	F	2.0	>1
629	S	T	All mutations	T	0.9987429289754871	1
629	S	L	All mutations	L	2.0	>1
629	S	K	All mutations	K	1.9981143934632306	>1
629	S	D	All mutations	D	1.9981143934632306	>1
629	S	W	All mutations	W	2.003142677561282	>1
629	S	S	All mutations	S	0.0031426775612822125	1
629	S	G	All mutations	G	1.0031426775612822	1
629	S	H	All mutations	H	1.9981143934632306	>1
629	S	N	All mutations	N	0.9981143934632307	1
629	S	E	All mutations	E	2.9981143934632306	>1
629	S	A	All mutations	A	1.9987429289754872	>1
629	S	Y	All mutations	Y	1.9981143934632306	>1
629	S	M	All mutations	M	2.0	>1
629	S	Q	All mutations	Q	2.9981143934632306	>1
629	S	C	All mutations	C	1.0031426775612822	1
629	S	V	All mutations	V	2.0	>1
629	S	I	All mutations	I	1.0	1
629	S	R	All mutations	R	1.0031426775612822	1
630	R	M	All mutations	M	1.3727215587680703	>1
630	R	F	All mutations	F	3.0	>1
630	R	H	All mutations	H	2.9792583280955376	>1
630	R	L	All mutations	L	1.9918290383406663	>1
630	R	S	All mutations	S	1.0207416719044626	1
630	R	N	All mutations	N	1.9956002514142048	>1
630	R	D	All mutations	D	2.9874292897548713	>1
630	R	E	All mutations	E	1.987429289754871	>1
630	R	Q	All mutations	Q	1.9792583280955374	>1
630	R	G	All mutations	G	1.012570710245129	1
630	R	I	All mutations	I	1.6436203645505971	>1
630	R	C	All mutations	C	2.0125707102451287	>1
630	R	P	All mutations	P	1.9918290383406663	>1
630	R	T	All mutations	T	1.0081709616593337	1
630	R	W	All mutations	W	1.3771213073538655	>1
630	R	V	All mutations	V	2.0	>1
630	R	K	All mutations	K	0.9956002514142049	1
630	R	A	All mutations	A	2.0	>1
630	R	Y	All mutations	Y	2.9874292897548713	>1
630	R	R	All mutations	R	0.01257071024512885	1
631	M	E	All mutations	E	1.9993714644877436	>1
631	M	H	All mutations	H	2.996228786926461	>1
631	M	Y	All mutations	Y	2.9993714644877434	>1
631	M	A	All mutations	A	1.9993714644877436	>1
631	M	N	All mutations	N	2.0050282840980516	>1
631	M	R	All mutations	R	1.0012570710245128	1
631	M	V	All mutations	V	0.9993714644877436	1
631	M	Q	All mutations	Q	1.9962287869264614	>1
631	M	W	All mutations	W	1.9993714644877436	>1
631	M	C	All mutations	C	2.9993714644877434	>1
631	M	I	All mutations	I	1.0050282840980516	1
631	M	F	All mutations	F	1.9993714644877436	>1
631	M	T	All mutations	T	1.0050282840980516	1
631	M	D	All mutations	D	2.9993714644877434	>1
631	M	G	All mutations	G	1.9993714644877436	>1
631	M	K	All mutations	K	1.0050282840980516	1
631	M	P	All mutations	P	1.9962287869264614	>1
631	M	L	All mutations	L	0.9956002514142049	1
631	M	M	All mutations	M	0.00502828409805154	1
631	M	S	All mutations	S	1.9993714644877436	>1
632	Q	I	All mutations	I	2.6813324952859836	>1
632	Q	V	All mutations	V	2.0	>1
632	Q	Y	All mutations	Y	2.0	>1
632	Q	F	All mutations	F	3.0	>1
632	Q	G	All mutations	G	2.0	>1
632	Q	Q	All mutations	Q	0.0	0
632	Q	E	All mutations	E	1.0	1
632	Q	W	All mutations	W	2.3186675047140164	>1
632	Q	L	All mutations	L	1.0	1
632	Q	K	All mutations	K	1.0	1
632	Q	D	All mutations	D	2.0	>1
632	Q	C	All mutations	C	3.0	>1
632	Q	T	All mutations	T	2.0	>1
632	Q	S	All mutations	S	2.0	>1
632	Q	M	All mutations	M	2.3186675047140164	>1
632	Q	A	All mutations	A	2.0	>1
632	Q	R	All mutations	R	1.0	1
632	Q	N	All mutations	N	2.0	>1
632	Q	H	All mutations	H	1.0	1
632	Q	P	All mutations	P	1.0	1
633	F	M	All mutations	M	2.0	>1
633	F	A	All mutations	A	2.0	>1
633	F	T	All mutations	T	2.0	>1
633	F	N	All mutations	N	2.0	>1
633	F	W	All mutations	W	2.0	>1
633	F	L	All mutations	L	1.0	1
633	F	F	All mutations	F	0.0	0
633	F	S	All mutations	S	1.0	1
633	F	K	All mutations	K	3.0	>1
633	F	Q	All mutations	Q	3.0	>1
633	F	G	All mutations	G	2.0	>1
633	F	E	All mutations	E	3.0	>1
633	F	P	All mutations	P	2.0	>1
633	F	C	All mutations	C	1.0	1
633	F	Y	All mutations	Y	1.0	1
633	F	R	All mutations	R	2.0	>1
633	F	H	All mutations	H	2.0	>1
633	F	V	All mutations	V	1.0	1
633	F	I	All mutations	I	1.0	1
633	F	D	All mutations	D	2.0	>1
634	S	H	All mutations	H	2.006913890634821	>1
634	S	D	All mutations	D	2.006913890634821	>1
634	S	T	All mutations	T	1.0006285355122564	1
634	S	E	All mutations	E	2.993086109365179	>1
634	S	M	All mutations	M	2.996228786926461	>1
634	S	P	All mutations	P	1.0006285355122564	1
634	S	K	All mutations	K	2.993086109365179	>1
634	S	C	All mutations	C	1.006913890634821	1
634	S	A	All mutations	A	1.0006285355122564	1
634	S	R	All mutations	R	2.0	>1
634	S	V	All mutations	V	1.9993714644877436	>1
634	S	I	All mutations	I	2.0025141420490256	>1
634	S	L	All mutations	L	1.9924575738529227	>1
634	S	N	All mutations	N	2.006913890634821	>1
634	S	G	All mutations	G	2.0	>1
634	S	Q	All mutations	Q	2.993086109365179	>1
634	S	W	All mutations	W	1.9968573224387178	>1
634	S	Y	All mutations	Y	1.006913890634821	1
634	S	S	All mutations	S	0.0006285355122564425	1
634	S	F	All mutations	F	1.0062853551225643	1
635	S	L	All mutations	L	1.9736015084852294	>1
635	S	C	All mutations	C	1.0257699560025142	1
635	S	N	All mutations	N	2.025769956002514	>1
635	S	Y	All mutations	Y	1.0257699560025142	1
635	S	G	All mutations	G	2.0	>1
635	S	S	All mutations	S	0.0006285355122564425	1
635	S	D	All mutations	D	2.025769956002514	>1
635	S	R	All mutations	R	2.0	>1
635	S	A	All mutations	A	1.0006285355122564	1
635	S	T	All mutations	T	1.0006285355122564	1
635	S	F	All mutations	F	1.0251414204902578	1
635	S	W	All mutations	W	1.993086109365179	>1
635	S	E	All mutations	E	2.974230043997486	>1
635	S	I	All mutations	I	2.0062853551225643	>1
635	S	P	All mutations	P	1.0006285355122564	1
635	S	H	All mutations	H	2.025769956002514	>1
635	S	V	All mutations	V	1.9993714644877436	>1
635	S	K	All mutations	K	2.974230043997486	>1
635	S	Q	All mutations	Q	2.974230043997486	>1
635	S	M	All mutations	M	2.992457573852923	>1
636	L	R	All mutations	R	1.120678818353237	>1
636	L	F	All mutations	F	1.8755499685732244	>1
636	L	V	All mutations	V	1.0	1
636	L	A	All mutations	A	2.0	>1
636	L	K	All mutations	K	2.0025141420490256	>1
636	L	I	All mutations	I	1.720301697045883	>1
636	L	C	All mutations	C	2.875549968573224	>1
636	L	P	All mutations	P	1.1219358893777498	>1
636	L	T	All mutations	T	1.9987429289754872	>1
636	L	N	All mutations	N	2.9949717159019484	>1
636	L	E	All mutations	E	2.003771213073539	>1
636	L	L	All mutations	L	0.001257071024512885	1
636	L	W	All mutations	W	2.157762413576367	>1
636	L	G	All mutations	G	2.0	>1
636	L	D	All mutations	D	2.996228786926461	>1
636	L	H	All mutations	H	2.118164676304211	>1
636	L	S	All mutations	S	1.879321181646763	>1
636	L	Y	All mutations	Y	2.875549968573224	>1
636	L	M	All mutations	M	1.2771841609050911	>1
636	L	Q	All mutations	Q	1.1257071024512886	>1
637	T	K	All mutations	K	1.9151477058453803	>1
637	T	F	All mutations	F	2.0509113764927718	>1
637	T	W	All mutations	W	2.9981143934632306	>1
637	T	M	All mutations	M	1.9641734758013827	>1
637	T	P	All mutations	P	1.033940917661848	1
637	T	S	All mutations	S	1.0	1
637	T	H	All mutations	H	2.08485229415462	>1
637	T	R	All mutations	R	1.9151477058453803	>1
637	T	E	All mutations	E	2.91514770584538	>1
637	T	Y	All mutations	Y	2.08485229415462	>1
637	T	C	All mutations	C	2.08485229415462	>1
637	T	T	All mutations	T	0.0339409176618479	1
637	T	Q	All mutations	Q	2.91514770584538	>1
637	T	I	All mutations	I	0.9679446888749215	1
637	T	N	All mutations	N	1.0848522941546197	1
637	T	G	All mutations	G	2.0	>1
637	T	A	All mutations	A	1.033940917661848	1
637	T	L	All mutations	L	1.966059082338152	>1
637	T	V	All mutations	V	1.966059082338152	>1
637	T	D	All mutations	D	2.08485229415462	>1
638	V	D	All mutations	D	2.0	>1
638	V	I	All mutations	I	1.837837837837838	>1
638	V	A	All mutations	A	1.0012570710245128	1
638	V	L	All mutations	L	0.9987429289754871	1
638	V	Y	All mutations	Y	2.9974858579509744	>1
638	V	H	All mutations	H	2.998742928975487	>1
638	V	N	All mutations	N	2.998742928975487	>1
638	V	M	All mutations	M	1.162162162162162	>1
638	V	W	All mutations	W	2.160905091137649	>1
638	V	S	All mutations	S	1.9987429289754872	>1
638	V	R	All mutations	R	2.0	>1
638	V	C	All mutations	C	2.9974858579509744	>1
638	V	F	All mutations	F	1.9974858579509742	>1
638	V	K	All mutations	K	2.001257071024513	>1
638	V	V	All mutations	V	0.001257071024512885	1
638	V	Q	All mutations	Q	2.001257071024513	>1
638	V	G	All mutations	G	1.0012570710245128	1
638	V	E	All mutations	E	1.0025141420490258	1
638	V	P	All mutations	P	2.0	>1
638	V	T	All mutations	T	2.0	>1
639	N	F	All mutations	F	2.0	>1
639	N	H	All mutations	H	1.0018856065367694	1
639	N	V	All mutations	V	2.0	>1
639	N	E	All mutations	E	2.0018856065367694	>1
639	N	D	All mutations	D	1.0018856065367694	1
639	N	N	All mutations	N	0.0018856065367693275	1
639	N	S	All mutations	S	0.9981143934632307	1
639	N	Q	All mutations	Q	2.0018856065367694	>1
639	N	W	All mutations	W	2.9981143934632306	>1
639	N	T	All mutations	T	1.0	1
639	N	L	All mutations	L	2.0	>1
639	N	P	All mutations	P	2.0	>1
639	N	I	All mutations	I	1.0	1
639	N	Y	All mutations	Y	1.0018856065367694	1
639	N	C	All mutations	C	1.9981143934632306	>1
639	N	K	All mutations	K	1.0018856065367694	1
639	N	R	All mutations	R	1.9981143934632306	>1
639	N	G	All mutations	G	1.9981143934632306	>1
639	N	M	All mutations	M	2.0	>1
639	N	A	All mutations	A	2.0	>1
640	V	H	All mutations	H	2.985543683218102	>1
640	V	M	All mutations	M	1.409176618478944	>1
640	V	G	All mutations	G	1.0150848522941547	1
640	V	P	All mutations	P	2.0	>1
640	V	E	All mutations	E	1.0295411690760528	1
640	V	T	All mutations	T	1.985543683218102	>1
640	V	R	All mutations	R	1.985543683218102	>1
640	V	W	All mutations	W	2.423004399748586	>1
640	V	C	All mutations	C	2.9849151477058453	>1
640	V	I	All mutations	I	1.5619107479572596	>1
640	V	Y	All mutations	Y	2.9849151477058453	>1
640	V	L	All mutations	L	0.9993714644877436	1
640	V	S	All mutations	S	1.9993714644877436	>1
640	V	Q	All mutations	Q	2.014456316781898	>1
640	V	A	All mutations	A	1.0150848522941547	1
640	V	K	All mutations	K	2.0	>1
640	V	F	All mutations	F	1.9849151477058453	>1
640	V	V	All mutations	V	0.01508485229415462	1
640	V	D	All mutations	D	2.0006285355122566	>1
640	V	N	All mutations	N	2.971087366436204	>1
641	R	M	All mutations	M	1.7976115650534255	>1
641	R	E	All mutations	E	2.0	>1
641	R	I	All mutations	I	1.3746071653048397	>1
641	R	N	All mutations	N	2.0861093651791327	>1
641	R	W	All mutations	W	1.711502199874293	>1
641	R	S	All mutations	S	1.0861093651791327	1
641	R	K	All mutations	K	1.0861093651791327	1
641	R	R	All mutations	R	0.0	0
641	R	G	All mutations	G	1.0	1
641	R	V	All mutations	V	2.0	>1
641	R	D	All mutations	D	3.0	>1
641	R	T	All mutations	T	1.0861093651791327	1
641	R	A	All mutations	A	2.0	>1
641	R	F	All mutations	F	3.0	>1
641	R	C	All mutations	C	2.0	>1
641	R	L	All mutations	L	1.9138906348208673	>1
641	R	H	All mutations	H	2.9138906348208673	>1
641	R	Y	All mutations	Y	3.0	>1
641	R	P	All mutations	P	1.9138906348208673	>1
641	R	Q	All mutations	Q	1.9138906348208673	>1
642	G	C	All mutations	C	1.578252671275927	>1
642	G	I	All mutations	I	2.0974230043997486	>1
642	G	Y	All mutations	Y	2.5782526712759273	>1
642	G	A	All mutations	A	1.0	1
642	G	G	All mutations	G	0.0	0
642	G	E	All mutations	E	1.421747328724073	>1
642	G	W	All mutations	W	1.9025769956002514	>1
642	G	V	All mutations	V	1.0	1
642	G	L	All mutations	L	2.0	>1
642	G	F	All mutations	F	2.5782526712759273	>1
642	G	N	All mutations	N	2.5782526712759273	>1
642	G	D	All mutations	D	1.578252671275927	>1
642	G	S	All mutations	S	1.578252671275927	>1
642	G	K	All mutations	K	2.4217473287240727	>1
642	G	T	All mutations	T	2.0	>1
642	G	M	All mutations	M	2.9025769956002514	>1
642	G	R	All mutations	R	1.0	1
642	G	P	All mutations	P	2.0	>1
642	G	H	All mutations	H	2.5782526712759273	>1
642	G	Q	All mutations	Q	2.4217473287240727	>1
643	S	V	All mutations	V	1.9987429289754872	>1
643	S	R	All mutations	R	2.0	>1
643	S	Y	All mutations	Y	1.8510370835952232	>1
643	S	P	All mutations	P	1.0	1
643	S	F	All mutations	F	1.8510370835952232	>1
643	S	E	All mutations	E	2.149591451917033	>1
643	S	S	All mutations	S	0.0018856065367693275	1
643	S	D	All mutations	D	2.847894406033941	>1
643	S	H	All mutations	H	2.8491514770584536	>1
643	S	N	All mutations	N	2.8485229415461975	>1
643	S	L	All mutations	L	1.1521055939660592	>1
643	S	W	All mutations	W	1.8881206788183533	>1
643	S	G	All mutations	G	1.9987429289754872	>1
643	S	Q	All mutations	Q	2.1508485229415464	>1
643	S	A	All mutations	A	0.9987429289754871	1
643	S	C	All mutations	C	1.8510370835952232	>1
643	S	I	All mutations	I	2.1131363922061595	>1
643	S	T	All mutations	T	0.9993714644877436	1
643	S	K	All mutations	K	2.1502199874292898	>1
643	S	M	All mutations	M	2.8856065367693273	>1
644	G	T	All mutations	T	2.0	>1
644	G	M	All mutations	M	2.9264613450659964	>1
644	G	K	All mutations	K	2.015713387806411	>1
644	G	P	All mutations	P	2.0	>1
644	G	R	All mutations	R	1.0	1
644	G	F	All mutations	F	2.984286612193589	>1
644	G	N	All mutations	N	2.984286612193589	>1
644	G	Q	All mutations	Q	2.015713387806411	>1
644	G	G	All mutations	G	0.0	0
644	G	H	All mutations	H	2.984286612193589	>1
644	G	S	All mutations	S	1.984286612193589	>1
644	G	I	All mutations	I	2.0735386549340036	>1
644	G	D	All mutations	D	1.984286612193589	>1
644	G	A	All mutations	A	1.0	1
644	G	V	All mutations	V	1.0	1
644	G	Y	All mutations	Y	2.984286612193589	>1
644	G	E	All mutations	E	1.015713387806411	1
644	G	C	All mutations	C	1.984286612193589	>1
644	G	L	All mutations	L	2.0	>1
644	G	W	All mutations	W	1.9264613450659962	>1
645	M	G	All mutations	G	2.0	>1
645	M	L	All mutations	L	0.9968573224387178	1
645	M	M	All mutations	M	0.006285355122564425	1
645	M	C	All mutations	C	2.996857322438718	>1
645	M	T	All mutations	T	1.0031426775612822	1
645	M	S	All mutations	S	1.9968573224387178	>1
645	M	A	All mutations	A	2.0	>1
645	M	Y	All mutations	Y	2.996857322438718	>1
645	M	E	All mutations	E	2.0	>1
645	M	H	All mutations	H	3.0	>1
645	M	K	All mutations	K	1.0031426775612822	1
645	M	I	All mutations	I	1.0	1
645	M	V	All mutations	V	1.0	1
645	M	Q	All mutations	Q	2.0	>1
645	M	F	All mutations	F	1.9968573224387178	>1
645	M	N	All mutations	N	2.003142677561282	>1
645	M	R	All mutations	R	1.0031426775612822	1
645	M	D	All mutations	D	3.0	>1
645	M	W	All mutations	W	2.0	>1
645	M	P	All mutations	P	2.0	>1
646	R	Q	All mutations	Q	1.9968573224387178	>1
646	R	Y	All mutations	Y	2.9974858579509744	>1
646	R	T	All mutations	T	1.0012570710245128	1
646	R	L	All mutations	L	1.9993714644877436	>1
646	R	K	All mutations	K	0.9987429289754871	1
646	R	A	All mutations	A	1.9993714644877436	>1
646	R	F	All mutations	F	3.0	>1
646	R	V	All mutations	V	1.9993714644877436	>1
646	R	D	All mutations	D	2.996857322438718	>1
646	R	C	All mutations	C	2.0025141420490256	>1
646	R	P	All mutations	P	1.9993714644877436	>1
646	R	H	All mutations	H	2.996857322438718	>1
646	R	I	All mutations	I	1.0351979886863607	1
646	R	S	All mutations	S	1.0037712130735386	1
646	R	W	All mutations	W	1.9685732243871779	>1
646	R	G	All mutations	G	1.0018856065367694	1
646	R	M	All mutations	M	1.967316153362665	>1
646	R	N	All mutations	N	1.9987429289754872	>1
646	R	E	All mutations	E	1.9968573224387178	>1
646	R	R	All mutations	R	0.0031426775612822125	1
647	I	K	All mutations	K	1.0559396605908233	1
647	I	R	All mutations	R	1.055311125078567	1
647	I	S	All mutations	S	1.9868007542426147	>1
647	I	W	All mutations	W	2.9578881206788186	>1
647	I	C	All mutations	C	2.986172218730358	>1
647	I	M	All mutations	M	1.0	1
647	I	F	All mutations	F	1.9861722187303583	>1
647	I	T	All mutations	T	1.0421118793211817	1
647	I	D	All mutations	D	2.9440603394091767	>1
647	I	P	All mutations	P	2.0	>1
647	I	A	All mutations	A	1.9578881206788183	>1
647	I	V	All mutations	V	0.9578881206788183	1
647	I	G	All mutations	G	1.9578881206788183	>1
647	I	L	All mutations	L	1.0	1
647	I	H	All mutations	H	2.986172218730358	>1
647	I	E	All mutations	E	1.97171590194846	>1
647	I	I	All mutations	I	0.0842237586423633	1
647	I	N	All mutations	N	2.02828409805154	>1
647	I	Q	All mutations	Q	2.013827781269642	>1
647	I	Y	All mutations	Y	2.986172218730358	>1
648	L	A	All mutations	A	1.9044626021370208	>1
648	L	H	All mutations	H	1.5744814582023885	>1
648	L	C	All mutations	C	2.460087994971716	>1
648	L	M	All mutations	M	1.619107479572596	>1
648	L	D	All mutations	D	2.382149591451917	>1
648	L	G	All mutations	G	1.9107479572595851	>1
648	L	E	All mutations	E	2.4393463230672534	>1
648	L	F	All mutations	F	1.4663733500942804	>1
648	L	R	All mutations	R	1.1011942174732872	>1
648	L	I	All mutations	I	1.3884349465744814	>1
648	L	K	All mutations	K	2.5260842237586423	>1
648	L	V	All mutations	V	0.9170333123821496	1
648	L	S	All mutations	S	1.9817724701445631	>1
648	L	N	All mutations	N	2.468887492143306	>1
648	L	W	All mutations	W	2.6040226272784412	>1
648	L	Y	All mutations	Y	2.460087994971716	>1
648	L	L	All mutations	L	0.09805153991200503	1
648	L	T	All mutations	T	1.9912005028284099	>1
648	L	Q	All mutations	Q	1.6316781898177246	>1
648	L	P	All mutations	P	1.0967944688874922	1
649	V	V	All mutations	V	0.08736643620364551	1
649	V	E	All mutations	E	1.092394720301697	1
649	V	W	All mutations	W	2.6681332495285983	>1
649	V	D	All mutations	D	2.082338152105594	>1
649	V	R	All mutations	R	1.9138906348208673	>1
649	V	K	All mutations	K	1.917661847894406	>1
649	V	Y	All mutations	Y	2.9949717159019484	>1
649	V	L	All mutations	L	1.0	1
649	V	Q	All mutations	Q	2.0050282840980516	>1
649	V	P	All mutations	P	2.0	>1
649	V	N	All mutations	N	2.907605279698303	>1
649	V	I	All mutations	I	1.2445003142677562	>1
649	V	T	All mutations	T	1.9126335637963545	>1
649	V	S	All mutations	S	1.9987429289754872	>1
649	V	A	All mutations	A	1.0873664362036455	1
649	V	M	All mutations	M	1.5807668133249528	>1
649	V	H	All mutations	H	2.9949717159019484	>1
649	V	F	All mutations	F	1.9949717159019484	>1
649	V	G	All mutations	G	1.0873664362036455	1
649	V	C	All mutations	C	2.9949717159019484	>1
650	R	R	All mutations	R	0.0	0
650	R	Y	All mutations	Y	3.0	>1
650	R	A	All mutations	A	2.0	>1
650	R	I	All mutations	I	1.3834066624764298	>1
650	R	Q	All mutations	Q	1.9641734758013827	>1
650	R	H	All mutations	H	2.964173475801383	>1
650	R	W	All mutations	W	1.6524198617221872	>1
650	R	T	All mutations	T	1.0358265241986173	1
650	R	L	All mutations	L	1.9641734758013827	>1
650	R	E	All mutations	E	2.0	>1
650	R	G	All mutations	G	1.0	1
650	R	N	All mutations	N	2.035826524198617	>1
650	R	P	All mutations	P	1.9641734758013827	>1
650	R	D	All mutations	D	3.0	>1
650	R	S	All mutations	S	1.0358265241986173	1
650	R	V	All mutations	V	2.0	>1
650	R	K	All mutations	K	1.0358265241986173	1
650	R	C	All mutations	C	2.0	>1
650	R	F	All mutations	F	3.0	>1
650	R	M	All mutations	M	1.6882463859208046	>1
651	G	E	All mutations	E	1.9912005028284099	>1
651	G	H	All mutations	H	2.0087994971715903	>1
651	G	R	All mutations	R	1.0	1
651	G	G	All mutations	G	0.0	0
651	G	C	All mutations	C	1.0087994971715901	1
651	G	D	All mutations	D	1.0087994971715901	1
651	G	Q	All mutations	Q	2.9912005028284097	>1
651	G	I	All mutations	I	2.0	>1
651	G	F	All mutations	F	2.0087994971715903	>1
651	G	T	All mutations	T	2.0	>1
651	G	L	All mutations	L	2.0	>1
651	G	K	All mutations	K	2.9912005028284097	>1
651	G	A	All mutations	A	1.0	1
651	G	Y	All mutations	Y	2.0087994971715903	>1
651	G	V	All mutations	V	1.0	1
651	G	P	All mutations	P	2.0	>1
651	G	M	All mutations	M	3.0	>1
651	G	W	All mutations	W	2.0	>1
651	G	N	All mutations	N	2.0087994971715903	>1
651	G	S	All mutations	S	1.0087994971715901	1
652	N	Y	All mutations	Y	1.0	1
652	N	T	All mutations	T	1.0	1
652	N	G	All mutations	G	2.0	>1
652	N	N	All mutations	N	0.0	0
652	N	Q	All mutations	Q	2.0	>1
652	N	P	All mutations	P	2.0	>1
652	N	I	All mutations	I	1.0	1
652	N	A	All mutations	A	2.0	>1
652	N	S	All mutations	S	1.0	1
652	N	F	All mutations	F	2.0	>1
652	N	C	All mutations	C	2.0	>1
652	N	V	All mutations	V	2.0	>1
652	N	W	All mutations	W	3.0	>1
652	N	D	All mutations	D	1.0	1
652	N	M	All mutations	M	2.0	>1
652	N	R	All mutations	R	2.0	>1
652	N	K	All mutations	K	1.0	1
652	N	H	All mutations	H	1.0	1
652	N	E	All mutations	E	2.0	>1
652	N	L	All mutations	L	2.0	>1
653	S	H	All mutations	H	2.0	>1
653	S	A	All mutations	A	1.0	1
653	S	I	All mutations	I	2.0	>1
653	S	S	All mutations	S	0.0	0
653	S	E	All mutations	E	3.0	>1
653	S	M	All mutations	M	3.0	>1
653	S	W	All mutations	W	2.0	>1
653	S	V	All mutations	V	2.0	>1
653	S	Y	All mutations	Y	1.0	1
653	S	N	All mutations	N	2.0	>1
653	S	K	All mutations	K	3.0	>1
653	S	P	All mutations	P	1.0	1
653	S	R	All mutations	R	2.0	>1
653	S	G	All mutations	G	2.0	>1
653	S	L	All mutations	L	2.0	>1
653	S	F	All mutations	F	1.0	1
653	S	C	All mutations	C	1.0	1
653	S	D	All mutations	D	2.0	>1
653	S	T	All mutations	T	1.0	1
653	S	Q	All mutations	Q	3.0	>1
654	P	Q	All mutations	Q	1.508485229415462	>1
654	P	W	All mutations	W	2.9566310496543053	>1
654	P	K	All mutations	K	2.505971087366436	>1
654	P	C	All mutations	C	2.4927718416090507	>1
654	P	M	All mutations	M	2.954745443117536	>1
654	P	I	All mutations	I	2.0414833438089253	>1
654	P	L	All mutations	L	1.0006285355122564	1
654	P	E	All mutations	E	2.5072281583909493	>1
654	P	D	All mutations	D	2.4927718416090507	>1
654	P	N	All mutations	N	2.491514770584538	>1
654	P	F	All mutations	F	2.4921433060967946	>1
654	P	S	All mutations	S	1.0006285355122564	1
654	P	R	All mutations	R	1.0	1
654	P	H	All mutations	H	1.4940289126335637	>1
654	P	G	All mutations	G	2.0	>1
654	P	T	All mutations	T	0.9993714644877436	1
654	P	P	All mutations	P	0.0018856065367693275	1
654	P	Y	All mutations	Y	2.4927718416090507	>1
654	P	V	All mutations	V	1.9993714644877436	>1
654	P	A	All mutations	A	1.0006285355122564	1
655	V	V	All mutations	V	0.00754242614707731	1
655	V	A	All mutations	A	0.9924575738529227	1
655	V	L	All mutations	L	1.0075424261470773	1
655	V	M	All mutations	M	1.1508485229415462	>1
655	V	I	All mutations	I	1.8642363293526085	>1
655	V	Y	All mutations	Y	2.9113764927718417	>1
655	V	T	All mutations	T	1.9924575738529227	>1
655	V	C	All mutations	C	2.9113764927718417	>1
655	V	Q	All mutations	Q	2.0886235072281583	>1
655	V	R	All mutations	R	2.0	>1
655	V	K	All mutations	K	2.0886235072281583	>1
655	V	G	All mutations	G	1.0	1
655	V	H	All mutations	H	2.9113764927718417	>1
655	V	S	All mutations	S	1.9924575738529227	>1
655	V	N	All mutations	N	2.9113764927718417	>1
655	V	E	All mutations	E	1.0886235072281585	1
655	V	W	All mutations	W	2.143306096794469	>1
655	V	P	All mutations	P	1.9924575738529227	>1
655	V	D	All mutations	D	1.9113764927718415	>1
655	V	F	All mutations	F	1.9189189189189189	>1
656	F	G	All mutations	G	2.0	>1
656	F	Y	All mutations	Y	1.0	1
656	F	C	All mutations	C	1.0	1
656	F	N	All mutations	N	2.0	>1
656	F	F	All mutations	F	0.0	0
656	F	Q	All mutations	Q	3.0	>1
656	F	A	All mutations	A	2.0	>1
656	F	H	All mutations	H	2.0	>1
656	F	D	All mutations	D	2.0	>1
656	F	V	All mutations	V	1.0	1
656	F	R	All mutations	R	2.0	>1
656	F	S	All mutations	S	1.0	1
656	F	P	All mutations	P	2.0	>1
656	F	W	All mutations	W	2.0	>1
656	F	T	All mutations	T	2.0	>1
656	F	K	All mutations	K	3.0	>1
656	F	I	All mutations	I	1.0	1
656	F	L	All mutations	L	1.0	1
656	F	E	All mutations	E	3.0	>1
656	F	M	All mutations	M	2.0	>1
657	N	Q	All mutations	Q	2.0006285355122566	>1
657	N	F	All mutations	F	2.001257071024513	>1
657	N	D	All mutations	D	1.0031426775612822	1
657	N	P	All mutations	P	2.0	>1
657	N	Y	All mutations	Y	1.0031426775612822	1
657	N	G	All mutations	G	1.9981143934632306	>1
657	N	T	All mutations	T	1.0	1
657	N	R	All mutations	R	1.9968573224387178	>1
657	N	W	All mutations	W	2.9981143934632306	>1
657	N	L	All mutations	L	2.0	>1
657	N	A	All mutations	A	2.0	>1
657	N	E	All mutations	E	2.0006285355122566	>1
657	N	C	All mutations	C	1.9993714644877436	>1
657	N	V	All mutations	V	2.0	>1
657	N	S	All mutations	S	0.9993714644877436	1
657	N	M	All mutations	M	2.0	>1
657	N	I	All mutations	I	1.0	1
657	N	H	All mutations	H	1.0031426775612822	1
657	N	K	All mutations	K	1.0006285355122564	1
657	N	N	All mutations	N	0.0031426775612822125	1
658	Y	R	All mutations	R	1.9981143934632306	>1
658	Y	G	All mutations	G	2.0	>1
658	Y	A	All mutations	A	2.0	>1
658	Y	Q	All mutations	Q	2.0	>1
658	Y	M	All mutations	M	2.9981143934632306	>1
658	Y	S	All mutations	S	1.0018856065367694	1
658	Y	D	All mutations	D	1.0018856065367694	1
658	Y	K	All mutations	K	2.0018856065367694	>1
658	Y	P	All mutations	P	1.9981143934632306	>1
658	Y	N	All mutations	N	1.0018856065367694	1
658	Y	V	All mutations	V	1.9981143934632306	>1
658	Y	L	All mutations	L	1.9962287869264614	>1
658	Y	F	All mutations	F	1.0	1
658	Y	Y	All mutations	Y	0.003771213073538655	1
658	Y	I	All mutations	I	1.9981143934632306	>1
658	Y	E	All mutations	E	2.0018856065367694	>1
658	Y	C	All mutations	C	1.0018856065367694	1
658	Y	T	All mutations	T	2.0	>1
658	Y	H	All mutations	H	1.0	1
658	Y	W	All mutations	W	2.0018856065367694	>1
659	N	C	All mutations	C	1.9962287869264614	>1
659	N	K	All mutations	K	1.0050282840980516	1
659	N	F	All mutations	F	1.9993714644877436	>1
659	N	L	All mutations	L	1.9987429289754872	>1
659	N	D	All mutations	D	1.0043997485857952	1
659	N	A	All mutations	A	2.0	>1
659	N	R	All mutations	R	1.9956002514142048	>1
659	N	I	All mutations	I	1.0	1
659	N	Q	All mutations	Q	2.003771213073539	>1
659	N	P	All mutations	P	1.9993714644877436	>1
659	N	S	All mutations	S	0.9968573224387178	1
659	N	E	All mutations	E	2.004399748585795	>1
659	N	T	All mutations	T	1.0006285355122564	1
659	N	M	All mutations	M	2.0	>1
659	N	V	All mutations	V	1.9993714644877436	>1
659	N	W	All mutations	W	2.996228786926461	>1
659	N	N	All mutations	N	0.00502828409805154	1
659	N	Y	All mutations	Y	1.0043997485857952	1
659	N	H	All mutations	H	1.0037712130735386	1
659	N	G	All mutations	G	1.9962287869264614	>1
660	K	Q	All mutations	Q	1.0263984915147706	1
660	K	G	All mutations	G	1.9736015084852294	>1
660	K	F	All mutations	F	3.0	>1
660	K	K	All mutations	K	0.026398491514770583	1
660	K	S	All mutations	S	1.9736015084852294	>1
660	K	D	All mutations	D	2.0263984915147706	>1
660	K	M	All mutations	M	1.1169076052796982	>1
660	K	I	All mutations	I	1.8830923947203018	>1
660	K	A	All mutations	A	2.0	>1
660	K	W	All mutations	W	2.0905091137649277	>1
660	K	H	All mutations	H	2.0263984915147706	>1
660	K	V	All mutations	V	2.0	>1
660	K	Y	All mutations	Y	2.0263984915147706	>1
660	K	N	All mutations	N	1.0263984915147706	1
660	K	T	All mutations	T	1.0	1
660	K	C	All mutations	C	2.9736015084852294	>1
660	K	R	All mutations	R	0.9736015084852294	1
660	K	P	All mutations	P	2.0	>1
660	K	L	All mutations	L	2.0	>1
660	K	E	All mutations	E	1.0263984915147706	1
661	A	G	All mutations	G	1.1313639220615965	>1
661	A	F	All mutations	F	2.4362036455059712	>1
661	A	R	All mutations	R	1.9522313010685104	>1
661	A	L	All mutations	L	1.917661847894406	>1
661	A	A	All mutations	A	0.1345065996228787	1
661	A	V	All mutations	V	1.1282212445003144	>1
661	A	T	All mutations	T	0.9509742300439975	1
661	A	M	All mutations	M	2.912005028284098	>1
661	A	S	All mutations	S	0.9239472030169704	1
661	A	W	All mutations	W	2.8881206788183533	>1
661	A	C	All mutations	C	2.4393463230672534	>1
661	A	N	All mutations	N	2.46637335009428	>1
661	A	D	All mutations	D	1.6499057196731615	>1
661	A	H	All mutations	H	2.518541797611565	>1
661	A	E	All mutations	E	1.6128221244500314	>1
661	A	I	All mutations	I	1.977372721558768	>1
661	A	Y	All mutations	Y	2.4393463230672534	>1
661	A	Q	All mutations	Q	2.481458202388435	>1
661	A	P	All mutations	P	1.0031426775612822	1
661	A	K	All mutations	K	2.4292897548711503	>1
662	T	R	All mutations	R	1.9277184160905092	>1
662	T	A	All mutations	A	1.0050282840980516	1
662	T	D	All mutations	D	2.0672532998114392	>1
662	T	M	All mutations	M	2.0	>1
662	T	W	All mutations	W	2.996228786926461	>1
662	T	E	All mutations	E	2.9302325581395348	>1
662	T	S	All mutations	S	0.9962287869264613	1
662	T	I	All mutations	I	1.0	1
662	T	K	All mutations	K	1.930232558139535	>1
662	T	Y	All mutations	Y	2.0672532998114392	>1
662	T	Q	All mutations	Q	2.9302325581395348	>1
662	T	N	All mutations	N	1.0672532998114392	1
662	T	P	All mutations	P	1.0050282840980516	1
662	T	T	All mutations	T	0.00502828409805154	1
662	T	V	All mutations	V	2.0	>1
662	T	C	All mutations	C	2.0647391577624137	>1
662	T	G	All mutations	G	1.9962287869264614	>1
662	T	H	All mutations	H	2.0672532998114392	>1
662	T	L	All mutations	L	2.0	>1
662	T	F	All mutations	F	2.068510370835952	>1
663	K	P	All mutations	P	2.0	>1
663	K	F	All mutations	F	3.0	>1
663	K	K	All mutations	K	0.0056568196103079825	1
663	K	S	All mutations	S	1.994343180389692	>1
663	K	W	All mutations	W	2.2859836580766815	>1
663	K	M	All mutations	M	1.2916404776869894	>1
663	K	T	All mutations	T	1.0	1
663	K	V	All mutations	V	2.0	>1
663	K	L	All mutations	L	2.0	>1
663	K	N	All mutations	N	1.005656819610308	1
663	K	G	All mutations	G	1.994343180389692	>1
663	K	A	All mutations	A	2.0	>1
663	K	R	All mutations	R	0.994343180389692	1
663	K	I	All mutations	I	1.7083595223130106	>1
663	K	D	All mutations	D	2.005656819610308	>1
663	K	H	All mutations	H	2.005656819610308	>1
663	K	Q	All mutations	Q	1.005656819610308	1
663	K	E	All mutations	E	1.005656819610308	1
663	K	Y	All mutations	Y	2.005656819610308	>1
663	K	C	All mutations	C	2.994343180389692	>1
664	R	T	All mutations	T	1.0094280326838467	1
664	R	Q	All mutations	Q	1.9962287869264614	>1
664	R	Y	All mutations	Y	2.993086109365179	>1
664	R	V	All mutations	V	2.0	>1
664	R	S	All mutations	S	1.0037712130735386	1
664	R	R	All mutations	R	0.0006285355122564425	1
664	R	K	All mutations	K	1.0150848522941547	1
664	R	C	All mutations	C	1.994343180389692	>1
664	R	M	All mutations	M	1.1024512884978002	>1
664	R	G	All mutations	G	1.0006285355122564	1
664	R	F	All mutations	F	2.9937146448774357	>1
664	R	W	All mutations	W	1.0936517913262098	1
664	R	I	All mutations	I	1.916404776869893	>1
664	R	A	All mutations	A	2.0	>1
664	R	L	All mutations	L	1.9905719673161533	>1
664	R	E	All mutations	E	2.005656819610308	>1
664	R	N	All mutations	N	2.0025141420490256	>1
664	R	H	All mutations	H	2.9836580766813325	>1
664	R	P	All mutations	P	1.9905719673161533	>1
664	R	D	All mutations	D	2.993086109365179	>1
665	L	I	All mutations	I	1.0050282840980516	1
665	L	V	All mutations	V	1.0	1
665	L	M	All mutations	M	1.9949717159019484	>1
665	L	L	All mutations	L	0.0	0
665	L	G	All mutations	G	2.0	>1
665	L	W	All mutations	W	2.9912005028284097	>1
665	L	K	All mutations	K	2.9824010056568198	>1
665	L	Q	All mutations	Q	1.9861722187303583	>1
665	L	C	All mutations	C	2.013827781269642	>1
665	L	F	All mutations	F	1.0138277812696417	1
665	L	N	All mutations	N	2.0175989943431802	>1
665	L	T	All mutations	T	2.0	>1
665	L	P	All mutations	P	1.0037712130735386	1
665	L	S	All mutations	S	1.9962287869264614	>1
665	L	H	All mutations	H	1.021370207416719	1
665	L	Y	All mutations	Y	2.013827781269642	>1
665	L	A	All mutations	A	2.0	>1
665	L	R	All mutations	R	1.0037712130735386	1
665	L	D	All mutations	D	2.0175989943431802	>1
665	L	E	All mutations	E	2.9824010056568198	>1
666	T	Y	All mutations	Y	2.891891891891892	>1
666	T	G	All mutations	G	1.901948460087995	>1
666	T	F	All mutations	F	2.8900062853551227	>1
666	T	K	All mutations	K	1.2049025769956003	>1
666	T	M	All mutations	M	2.0402262727844125	>1
666	T	W	All mutations	W	2.9409176618478945	>1
666	T	H	All mutations	H	2.893777498428661	>1
666	T	R	All mutations	R	1.1935889377749842	>1
666	T	Q	All mutations	Q	2.1049654305468257	>1
666	T	V	All mutations	V	1.8994343180389692	>1
666	T	S	All mutations	S	1.0006285355122564	1
666	T	C	All mutations	C	2.8925204274041483	>1
666	T	D	All mutations	D	2.7957259585166563	>1
666	T	A	All mutations	A	0.9050911376492772	1
666	T	T	All mutations	T	0.10307982401005657	1
666	T	N	All mutations	N	1.9937146448774357	>1
666	T	E	All mutations	E	2.006913890634821	>1
666	T	I	All mutations	I	1.154619736015085	>1
666	T	P	All mutations	P	1.0031426775612822	1
666	T	L	All mutations	L	1.9956002514142048	>1
667	V	D	All mutations	D	1.1514770584538025	>1
667	V	A	All mutations	A	1.021370207416719	1
667	V	E	All mutations	E	1.8912633563796355	>1
667	V	W	All mutations	W	2.903834066624764	>1
667	V	K	All mutations	K	2.8485229415461975	>1
667	V	L	All mutations	L	1.0	1
667	V	P	All mutations	P	2.0	>1
667	V	H	All mutations	H	2.1301068510370835	>1
667	V	F	All mutations	F	1.1301068510370835	>1
667	V	Q	All mutations	Q	2.8698931489629165	>1
667	V	N	All mutations	N	2.1087366436203645	>1
667	V	T	All mutations	T	1.978629792583281	>1
667	V	G	All mutations	G	1.021370207416719	1
667	V	V	All mutations	V	0.021370207416719043	1
667	V	M	All mutations	M	1.8824638592080452	>1
667	V	S	All mutations	S	1.978629792583281	>1
667	V	Y	All mutations	Y	2.1301068510370835	>1
667	V	I	All mutations	I	1.0747957259585166	1
667	V	C	All mutations	C	2.1301068510370835	>1
667	V	R	All mutations	R	2.0	>1
668	L	T	All mutations	T	2.0	>1
668	L	V	All mutations	V	1.0	1
668	L	K	All mutations	K	2.989943431803897	>1
668	L	M	All mutations	M	1.9962287869264614	>1
668	L	P	All mutations	P	1.0031426775612822	1
668	L	E	All mutations	E	2.989943431803897	>1
668	L	F	All mutations	F	1.006913890634821	1
668	L	L	All mutations	L	0.0	0
668	L	Q	All mutations	Q	1.993086109365179	>1
668	L	I	All mutations	I	1.0037712130735386	1
668	L	A	All mutations	A	2.0	>1
668	L	Y	All mutations	Y	2.006913890634821	>1
668	L	H	All mutations	H	1.0131992457573853	1
668	L	W	All mutations	W	2.993086109365179	>1
668	L	C	All mutations	C	2.006913890634821	>1
668	L	G	All mutations	G	2.0	>1
668	L	N	All mutations	N	2.010056568196103	>1
668	L	D	All mutations	D	2.010056568196103	>1
668	L	R	All mutations	R	1.0031426775612822	1
668	L	S	All mutations	S	1.9968573224387178	>1
669	G	C	All mutations	C	1.9968573224387178	>1
669	G	G	All mutations	G	0.0	0
669	G	S	All mutations	S	1.9968573224387178	>1
669	G	E	All mutations	E	1.0031426775612822	1
669	G	N	All mutations	N	2.996857322438718	>1
669	G	T	All mutations	T	2.0	>1
669	G	H	All mutations	H	2.996857322438718	>1
669	G	R	All mutations	R	1.0	1
669	G	L	All mutations	L	2.0	>1
669	G	P	All mutations	P	2.0	>1
669	G	M	All mutations	M	2.3859208045254556	>1
669	G	Q	All mutations	Q	2.003142677561282	>1
669	G	W	All mutations	W	1.3859208045254556	>1
669	G	F	All mutations	F	2.996857322438718	>1
669	G	A	All mutations	A	1.0	1
669	G	V	All mutations	V	1.0	1
669	G	D	All mutations	D	1.9968573224387178	>1
669	G	Y	All mutations	Y	2.996857322438718	>1
669	G	I	All mutations	I	2.6140791954745444	>1
669	G	K	All mutations	K	2.003142677561282	>1
670	K	T	All mutations	T	1.0	1
670	K	N	All mutations	N	1.0	1
670	K	S	All mutations	S	2.0	>1
670	K	I	All mutations	I	1.4795725958516657	>1
670	K	Q	All mutations	Q	1.0	1
670	K	Y	All mutations	Y	2.0	>1
670	K	C	All mutations	C	3.0	>1
670	K	M	All mutations	M	1.5204274041483343	>1
670	K	F	All mutations	F	3.0	>1
670	K	R	All mutations	R	1.0	1
670	K	A	All mutations	A	2.0	>1
670	K	D	All mutations	D	2.0	>1
670	K	L	All mutations	L	2.0	>1
670	K	H	All mutations	H	2.0	>1
670	K	E	All mutations	E	1.0	1
670	K	G	All mutations	G	2.0	>1
670	K	P	All mutations	P	2.0	>1
670	K	K	All mutations	K	0.0	0
670	K	V	All mutations	V	2.0	>1
670	K	W	All mutations	W	2.5204274041483345	>1
671	D	G	All mutations	G	1.0	1
671	D	N	All mutations	N	1.0012570710245128	1
671	D	C	All mutations	C	2.001257071024513	>1
671	D	P	All mutations	P	2.0	>1
671	D	H	All mutations	H	1.0012570710245128	1
671	D	R	All mutations	R	2.0	>1
671	D	D	All mutations	D	0.001257071024512885	1
671	D	T	All mutations	T	2.0	>1
671	D	Y	All mutations	Y	1.0012570710245128	1
671	D	W	All mutations	W	2.9993714644877434	>1
671	D	A	All mutations	A	1.0	1
671	D	M	All mutations	M	2.9993714644877434	>1
671	D	K	All mutations	K	1.9987429289754872	>1
671	D	L	All mutations	L	2.0	>1
671	D	Q	All mutations	Q	1.9987429289754872	>1
671	D	I	All mutations	I	2.0006285355122566	>1
671	D	F	All mutations	F	2.001257071024513	>1
671	D	V	All mutations	V	1.0	1
671	D	S	All mutations	S	2.0	>1
671	D	E	All mutations	E	0.9987429289754871	1
672	A	Y	All mutations	Y	2.983029541169076	>1
672	A	W	All mutations	W	2.983029541169076	>1
672	A	E	All mutations	E	1.0169704588309239	1
672	A	P	All mutations	P	1.0	1
672	A	I	All mutations	I	2.016970458830924	>1
672	A	L	All mutations	L	2.0	>1
672	A	A	All mutations	A	0.0	0
672	A	D	All mutations	D	1.9830295411690761	>1
672	A	G	All mutations	G	1.0	1
672	A	F	All mutations	F	2.983029541169076	>1
672	A	N	All mutations	N	2.983029541169076	>1
672	A	V	All mutations	V	1.0	1
672	A	M	All mutations	M	2.983029541169076	>1
672	A	C	All mutations	C	2.983029541169076	>1
672	A	R	All mutations	R	2.0	>1
672	A	T	All mutations	T	1.0	1
672	A	K	All mutations	K	2.016970458830924	>1
672	A	S	All mutations	S	1.0	1
672	A	Q	All mutations	Q	2.016970458830924	>1
672	A	H	All mutations	H	2.983029541169076	>1
673	G	P	All mutations	P	2.0	>1
673	G	M	All mutations	M	2.992457573852923	>1
673	G	W	All mutations	W	1.9924575738529227	>1
673	G	H	All mutations	H	2.027027027027027	>1
673	G	Q	All mutations	Q	2.972972972972973	>1
673	G	K	All mutations	K	2.972972972972973	>1
673	G	V	All mutations	V	1.0	1
673	G	I	All mutations	I	2.007542426147077	>1
673	G	L	All mutations	L	2.0	>1
673	G	D	All mutations	D	1.027027027027027	1
673	G	A	All mutations	A	1.0	1
673	G	E	All mutations	E	1.972972972972973	>1
673	G	S	All mutations	S	1.027027027027027	1
673	G	F	All mutations	F	2.027027027027027	>1
673	G	N	All mutations	N	2.027027027027027	>1
673	G	Y	All mutations	Y	2.027027027027027	>1
673	G	C	All mutations	C	1.027027027027027	1
673	G	T	All mutations	T	2.0	>1
673	G	G	All mutations	G	0.0	0
673	G	R	All mutations	R	1.0	1
674	A	L	All mutations	L	1.988686360779384	>1
674	A	N	All mutations	N	2.9157762413576367	>1
674	A	Q	All mutations	Q	2.0773098680075424	>1
674	A	V	All mutations	V	1.022627278441232	1
674	A	F	All mutations	F	2.9069767441860463	>1
674	A	W	All mutations	W	2.9308610936517914	>1
674	A	E	All mutations	E	1.0999371464487744	1
674	A	T	All mutations	T	0.9930861093651792	1
674	A	P	All mutations	P	1.0	1
674	A	I	All mutations	I	2.046511627906977	>1
674	A	R	All mutations	R	1.993086109365179	>1
674	A	M	All mutations	M	2.9396605908233817	>1
674	A	G	All mutations	G	1.022627278441232	1
674	A	H	All mutations	H	2.9226901319924576	>1
674	A	A	All mutations	A	0.02262727844123193	1
674	A	C	All mutations	C	2.9069767441860463	>1
674	A	S	All mutations	S	0.9842866121935889	1
674	A	K	All mutations	K	2.0703959773727214	>1
674	A	D	All mutations	D	1.9453174104336894	>1
674	A	Y	All mutations	Y	2.9069767441860463	>1
675	L	C	All mutations	C	2.048397234443746	>1
675	L	S	All mutations	S	1.1275927089880577	>1
675	L	A	All mutations	A	2.0	>1
675	L	V	All mutations	V	1.0	1
675	L	F	All mutations	F	1.048397234443746	1
675	L	I	All mutations	I	1.6825895663104966	>1
675	L	E	All mutations	E	2.0791954745443118	>1
675	L	Q	All mutations	Q	1.951602765556254	>1
675	L	K	All mutations	K	2.0791954745443118	>1
675	L	T	All mutations	T	2.0	>1
675	L	D	All mutations	D	2.9208045254556882	>1
675	L	N	All mutations	N	2.9208045254556882	>1
675	L	R	All mutations	R	1.8724072910119423	>1
675	L	W	All mutations	W	1.4450031426775614	>1
675	L	G	All mutations	G	2.0	>1
675	L	L	All mutations	L	0.0	0
675	L	P	All mutations	P	1.8724072910119423	>1
675	L	M	All mutations	M	1.3174104336895034	>1
675	L	Y	All mutations	Y	2.048397234443746	>1
675	L	H	All mutations	H	2.7932118164676303	>1
676	T	G	All mutations	G	1.9296040226272784	>1
676	T	L	All mutations	L	1.813953488372093	>1
676	T	R	All mutations	R	1.5311125078566938	>1
676	T	P	All mutations	P	1.181646763042112	>1
676	T	I	All mutations	I	1.015713387806411	1
676	T	Y	All mutations	Y	2.509742300439975	>1
676	T	V	All mutations	V	1.7479572595851665	>1
676	T	S	All mutations	S	1.1357636706473915	>1
676	T	F	All mutations	F	2.3287240729101195	>1
676	T	M	All mutations	M	1.76681332495286	>1
676	T	T	All mutations	T	0.25769956002514144	1
676	T	A	All mutations	A	1.1143934632306725	>1
676	T	H	All mutations	H	2.508485229415462	>1
676	T	N	All mutations	N	1.5845380263984916	>1
676	T	K	All mutations	K	1.5600251414204902	>1
676	T	E	All mutations	E	2.416719044626021	>1
676	T	D	All mutations	D	2.441231929604023	>1
676	T	Q	All mutations	Q	2.483972344437461	>1
676	T	C	All mutations	C	2.5103708359522314	>1
676	T	W	All mutations	W	2.8736643620364553	>1
677	E	V	All mutations	V	1.0006285355122564	1
677	E	R	All mutations	R	1.9692017598994342	>1
677	E	N	All mutations	N	2.028912633563796	>1
677	E	C	All mutations	C	2.9692017598994345	>1
677	E	T	All mutations	T	1.9993714644877436	>1
677	E	S	All mutations	S	2.0	>1
677	E	G	All mutations	G	0.9704588309239472	1
677	E	Y	All mutations	Y	2.0295411690760528	>1
677	E	M	All mutations	M	2.8189817724701447	>1
677	E	E	All mutations	E	0.03142677561282212	1
677	E	Q	All mutations	Q	1.0307982401005658	1
677	E	P	All mutations	P	2.0	>1
677	E	I	All mutations	I	2.1797611565053425	>1
677	E	W	All mutations	W	2.789440603394092	>1
677	E	D	All mutations	D	1.0301697045883091	1
677	E	L	All mutations	L	2.0	>1
677	E	K	All mutations	K	1.0301697045883091	1
677	E	A	All mutations	A	1.0006285355122564	1
677	E	F	All mutations	F	2.9993714644877434	>1
677	E	H	All mutations	H	2.0295411690760528	>1
678	D	Y	All mutations	Y	1.0043997485857952	1
678	D	S	All mutations	S	1.993086109365179	>1
678	D	V	All mutations	V	1.005656819610308	1
678	D	D	All mutations	D	0.01571338780641106	1
678	D	N	All mutations	N	1.0100565681961031	1
678	D	A	All mutations	A	1.005656819610308	1
678	D	T	All mutations	T	2.0	>1
678	D	G	All mutations	G	1.0043997485857952	1
678	D	R	All mutations	R	1.9987429289754872	>1
678	D	Q	All mutations	Q	1.9924575738529227	>1
678	D	E	All mutations	E	0.9981143934632307	1
678	D	K	All mutations	K	1.9924575738529227	>1
678	D	C	All mutations	C	2.0018856065367694	>1
678	D	H	All mutations	H	1.0100565681961031	1
678	D	W	All mutations	W	2.9868007542426147	>1
678	D	L	All mutations	L	2.0	>1
678	D	I	All mutations	I	2.0062853551225643	>1
678	D	P	All mutations	P	2.0	>1
678	D	F	All mutations	F	2.003142677561282	>1
678	D	M	All mutations	M	2.9937146448774357	>1
679	P	H	All mutations	H	1.9622878692646135	>1
679	P	S	All mutations	S	1.0012570710245128	1
679	P	L	All mutations	L	0.9974858579509742	1
679	P	C	All mutations	C	2.9591451917033313	>1
679	P	Q	All mutations	Q	1.0402262727844123	1
679	P	I	All mutations	I	2.1257071024512886	>1
679	P	R	All mutations	R	1.0018856065367694	1
679	P	V	All mutations	V	1.9974858579509742	>1
679	P	A	All mutations	A	1.0031426775612822	1
679	P	Y	All mutations	Y	2.9585166561910747	>1
679	P	K	All mutations	K	2.038340666247643	>1
679	P	G	All mutations	G	2.0	>1
679	P	D	All mutations	D	2.960402262727844	>1
679	P	T	All mutations	T	1.0031426775612822	1
679	P	P	All mutations	P	0.00502828409805154	1
679	P	N	All mutations	N	2.960402262727844	>1
679	P	F	All mutations	F	2.9566310496543053	>1
679	P	W	All mutations	W	2.8698931489629165	>1
679	P	E	All mutations	E	2.038340666247643	>1
679	P	M	All mutations	M	2.86926461345066	>1
680	D	G	All mutations	G	1.076681332495286	1
680	D	P	All mutations	P	2.0	>1
680	D	L	All mutations	L	2.0	>1
680	D	S	All mutations	S	1.9195474544311755	>1
680	D	F	All mutations	F	1.9993714644877436	>1
680	D	Q	All mutations	Q	2.0018856065367694	>1
680	D	H	All mutations	H	1.0018856065367694	1
680	D	W	All mutations	W	2.9974858579509744	>1
680	D	M	All mutations	M	2.922061596480201	>1
680	D	D	All mutations	D	0.08045254556882464	1
680	D	E	All mutations	E	1.0804525455688245	1
680	D	T	All mutations	T	1.922061596480201	>1
680	D	I	All mutations	I	1.922061596480201	>1
680	D	V	All mutations	V	1.0785669390320554	1
680	D	N	All mutations	N	0.9239472030169704	1
680	D	K	All mutations	K	1.9239472030169704	>1
680	D	R	All mutations	R	1.9981143934632306	>1
680	D	Y	All mutations	Y	1.0012570710245128	1
680	D	C	All mutations	C	1.9974858579509742	>1
680	D	A	All mutations	A	1.0785669390320554	1
681	E	K	All mutations	K	1.0006285355122564	1
681	E	S	All mutations	S	2.0	>1
681	E	P	All mutations	P	2.0	>1
681	E	R	All mutations	R	2.0	>1
681	E	Q	All mutations	Q	1.0006285355122564	1
681	E	E	All mutations	E	0.0006285355122564425	1
681	E	L	All mutations	L	2.0	>1
681	E	Y	All mutations	Y	1.9993714644877436	>1
681	E	V	All mutations	V	1.0	1
681	E	I	All mutations	I	2.5531112507856695	>1
681	E	A	All mutations	A	1.0	1
681	E	W	All mutations	W	2.4468887492143305	>1
681	E	C	All mutations	C	2.9993714644877434	>1
681	E	H	All mutations	H	1.9993714644877436	>1
681	E	F	All mutations	F	2.9993714644877434	>1
681	E	T	All mutations	T	2.0	>1
681	E	N	All mutations	N	1.9993714644877436	>1
681	E	M	All mutations	M	2.4468887492143305	>1
681	E	D	All mutations	D	0.9993714644877436	1
681	E	G	All mutations	G	1.0	1
682	G	S	All mutations	S	1.5273412947831553	>1
682	G	K	All mutations	K	2.462602137020742	>1
682	G	T	All mutations	T	1.9949717159019484	>1
682	G	N	All mutations	N	2.527341294783155	>1
682	G	D	All mutations	D	1.5373978629792584	>1
682	G	A	All mutations	A	1.0050282840980516	1
682	G	R	All mutations	R	1.0	1
682	G	P	All mutations	P	2.0	>1
682	G	Q	All mutations	Q	2.4676304211187934	>1
682	G	F	All mutations	F	2.5323695788812066	>1
682	G	H	All mutations	H	2.5323695788812066	>1
682	G	C	All mutations	C	1.5323695788812068	>1
682	G	E	All mutations	E	1.4726587052168447	>1
682	G	W	All mutations	W	1.8045254556882464	>1
682	G	G	All mutations	G	0.00502828409805154	1
682	G	L	All mutations	L	2.0	>1
682	G	V	All mutations	V	1.0050282840980516	1
682	G	Y	All mutations	Y	2.5323695788812066	>1
682	G	I	All mutations	I	2.1904462602137023	>1
682	G	M	All mutations	M	2.799497171590195	>1
683	T	P	All mutations	P	1.0025141420490258	1
683	T	N	All mutations	N	2.015713387806411	>1
683	T	A	All mutations	A	0.9761156505342552	1
683	T	H	All mutations	H	2.981772470144563	>1
683	T	I	All mutations	I	1.0936517913262098	1
683	T	D	All mutations	D	2.9553739786297926	>1
683	T	L	All mutations	L	1.9968573224387178	>1
683	T	S	All mutations	S	1.0050282840980516	1
683	T	K	All mutations	K	1.038340666247643	1
683	T	T	All mutations	T	0.036455059710873663	1
683	T	F	All mutations	F	2.9880578252671275	>1
683	T	M	All mutations	M	1.9679446888749215	>1
683	T	V	All mutations	V	1.9704588309239472	>1
683	T	C	All mutations	C	2.988686360779384	>1
683	T	Y	All mutations	Y	2.984286612193589	>1
683	T	E	All mutations	E	1.9780012570710246	>1
683	T	W	All mutations	W	2.9371464487743557	>1
683	T	R	All mutations	R	1.0402262727844123	1
683	T	G	All mutations	G	1.9710873664362036	>1
683	T	Q	All mutations	Q	2.004399748585795	>1
684	A	G	All mutations	G	1.1175361407919548	>1
684	A	Y	All mutations	Y	2.4267756128221243	>1
684	A	I	All mutations	I	1.8981772470144562	>1
684	A	A	All mutations	A	0.11942174732872407	1
684	A	Q	All mutations	Q	2.5575109993714644	>1
684	A	F	All mutations	F	2.426147077309868	>1
684	A	M	All mutations	M	2.893148962916405	>1
684	A	C	All mutations	C	2.427404148334381	>1
684	A	E	All mutations	E	1.6750471401634193	>1
684	A	P	All mutations	P	1.0018856065367694	1
684	A	D	All mutations	D	1.5587680703959774	>1
684	A	W	All mutations	W	2.983029541169076	>1
684	A	S	All mutations	S	0.9874292897548711	1
684	A	N	All mutations	N	2.338152105593966	>1
684	A	V	All mutations	V	1.1162790697674418	>1
684	A	R	All mutations	R	1.9063482086737902	>1
684	A	L	All mutations	L	1.9880578252671275	>1
684	A	T	All mutations	T	0.8988057825267127	1
684	A	K	All mutations	K	2.454431175361408	>1
684	A	H	All mutations	H	2.441231929604023	>1
685	G	D	All mutations	D	2.0	>1
685	G	K	All mutations	K	2.0	>1
685	G	S	All mutations	S	2.0	>1
685	G	C	All mutations	C	2.0	>1
685	G	A	All mutations	A	1.0	1
685	G	I	All mutations	I	2.116279069767442	>1
685	G	P	All mutations	P	2.0	>1
685	G	M	All mutations	M	2.883720930232558	>1
685	G	Q	All mutations	Q	2.0	>1
685	G	L	All mutations	L	2.0	>1
685	G	R	All mutations	R	1.0	1
685	G	N	All mutations	N	3.0	>1
685	G	G	All mutations	G	0.0	0
685	G	V	All mutations	V	1.0	1
685	G	T	All mutations	T	2.0	>1
685	G	Y	All mutations	Y	3.0	>1
685	G	F	All mutations	F	3.0	>1
685	G	W	All mutations	W	1.8837209302325582	>1
685	G	H	All mutations	H	3.0	>1
685	G	E	All mutations	E	1.0	1
686	V	L	All mutations	L	1.0	1
686	V	D	All mutations	D	1.9861722187303583	>1
686	V	C	All mutations	C	2.984286612193589	>1
686	V	T	All mutations	T	1.9981143934632306	>1
686	V	R	All mutations	R	1.9981143934632306	>1
686	V	W	All mutations	W	2.248271527341295	>1
686	V	K	All mutations	K	2.013827781269642	>1
686	V	E	All mutations	E	1.0175989943431805	1
686	V	Q	All mutations	Q	2.015713387806411	>1
686	V	S	All mutations	S	2.0	>1
686	V	Y	All mutations	Y	2.984286612193589	>1
686	V	V	All mutations	V	0.0018856065367693275	1
686	V	F	All mutations	F	1.984286612193589	>1
686	V	M	All mutations	M	1.2463859208045254	>1
686	V	I	All mutations	I	1.7498428661219358	>1
686	V	N	All mutations	N	2.9824010056568198	>1
686	V	A	All mutations	A	1.0018856065367694	1
686	V	H	All mutations	H	2.984286612193589	>1
686	V	P	All mutations	P	2.0	>1
686	V	G	All mutations	G	1.0018856065367694	1
687	E	N	All mutations	N	2.0	>1
687	E	T	All mutations	T	2.0	>1
687	E	M	All mutations	M	2.529855436832181	>1
687	E	A	All mutations	A	1.0	1
687	E	R	All mutations	R	2.0	>1
687	E	E	All mutations	E	0.0	0
687	E	Q	All mutations	Q	1.0	1
687	E	D	All mutations	D	1.0	1
687	E	V	All mutations	V	1.0	1
687	E	P	All mutations	P	2.0	>1
687	E	L	All mutations	L	2.0	>1
687	E	W	All mutations	W	2.529855436832181	>1
687	E	H	All mutations	H	2.0	>1
687	E	Y	All mutations	Y	2.0	>1
687	E	C	All mutations	C	3.0	>1
687	E	F	All mutations	F	3.0	>1
687	E	I	All mutations	I	2.470144563167819	>1
687	E	G	All mutations	G	1.0	1
687	E	S	All mutations	S	2.0	>1
687	E	K	All mutations	K	1.0	1
688	S	W	All mutations	W	1.9968573224387178	>1
688	S	I	All mutations	I	2.0018856065367694	>1
688	S	T	All mutations	T	1.0012570710245128	1
688	S	K	All mutations	K	2.996228786926461	>1
688	S	D	All mutations	D	2.003771213073539	>1
688	S	Y	All mutations	Y	1.0037712130735386	1
688	S	H	All mutations	H	2.003771213073539	>1
688	S	M	All mutations	M	2.995600251414205	>1
688	S	L	All mutations	L	1.9949717159019484	>1
688	S	R	All mutations	R	2.0	>1
688	S	S	All mutations	S	0.001257071024512885	1
688	S	G	All mutations	G	2.0	>1
688	S	V	All mutations	V	1.9987429289754872	>1
688	S	F	All mutations	F	1.0025141420490258	1
688	S	N	All mutations	N	2.003771213073539	>1
688	S	P	All mutations	P	1.0012570710245128	1
688	S	A	All mutations	A	1.0012570710245128	1
688	S	Q	All mutations	Q	2.996228786926461	>1
688	S	C	All mutations	C	1.0037712130735386	1
688	S	E	All mutations	E	2.996228786926461	>1
689	A	N	All mutations	N	2.5782526712759273	>1
689	A	Y	All mutations	Y	2.5782526712759273	>1
689	A	A	All mutations	A	0.0	0
689	A	M	All mutations	M	2.7888120678818353	>1
689	A	C	All mutations	C	2.5782526712759273	>1
689	A	L	All mutations	L	2.0	>1
689	A	W	All mutations	W	2.7888120678818353	>1
689	A	R	All mutations	R	2.0	>1
689	A	H	All mutations	H	2.5782526712759273	>1
689	A	D	All mutations	D	1.578252671275927	>1
689	A	I	All mutations	I	2.2111879321181647	>1
689	A	K	All mutations	K	2.4217473287240727	>1
689	A	T	All mutations	T	1.0	1
689	A	F	All mutations	F	2.5782526712759273	>1
689	A	S	All mutations	S	1.0	1
689	A	E	All mutations	E	1.421747328724073	>1
689	A	Q	All mutations	Q	2.4217473287240727	>1
689	A	P	All mutations	P	1.0	1
689	A	V	All mutations	V	1.0	1
689	A	G	All mutations	G	1.0	1
690	V	K	All mutations	K	2.458830923947203	>1
690	V	R	All mutations	R	2.0	>1
690	V	H	All mutations	H	2.541169076052797	>1
690	V	A	All mutations	A	1.0	1
690	V	C	All mutations	C	2.541169076052797	>1
690	V	Q	All mutations	Q	2.458830923947203	>1
690	V	I	All mutations	I	1.0546825895663106	1
690	V	L	All mutations	L	1.0	1
690	V	T	All mutations	T	2.0	>1
690	V	W	All mutations	W	2.9453174104336894	>1
690	V	S	All mutations	S	2.0	>1
690	V	N	All mutations	N	2.541169076052797	>1
690	V	E	All mutations	E	1.458830923947203	>1
690	V	F	All mutations	F	1.541169076052797	>1
690	V	V	All mutations	V	0.0	0
690	V	D	All mutations	D	1.541169076052797	>1
690	V	M	All mutations	M	1.9453174104336894	>1
690	V	G	All mutations	G	1.0	1
690	V	Y	All mutations	Y	2.541169076052797	>1
690	V	P	All mutations	P	2.0	>1
691	L	M	All mutations	M	1.5801382778126964	>1
691	L	C	All mutations	C	2.3670647391577626	>1
691	L	V	All mutations	V	1.0	1
691	L	I	All mutations	I	1.4198617221873036	>1
691	L	P	All mutations	P	1.6323067253299812	>1
691	L	A	All mutations	A	2.0	>1
691	L	S	All mutations	S	1.3676932746700188	>1
691	L	N	All mutations	N	2.9993714644877434	>1
691	L	H	All mutations	H	2.6316781898177246	>1
691	L	W	All mutations	W	1.9478315524827152	>1
691	L	G	All mutations	G	2.0	>1
691	L	F	All mutations	F	1.3670647391577624	>1
691	L	K	All mutations	K	2.0006285355122566	>1
691	L	R	All mutations	R	1.6323067253299812	>1
691	L	T	All mutations	T	2.0	>1
691	L	L	All mutations	L	0.0	0
691	L	Y	All mutations	Y	2.3670647391577626	>1
691	L	D	All mutations	D	2.9993714644877434	>1
691	L	Q	All mutations	Q	1.6329352608422376	>1
691	L	E	All mutations	E	2.0006285355122566	>1
692	R	Q	All mutations	Q	1.9849151477058453	>1
692	R	I	All mutations	I	1.2551854179761157	>1
692	R	P	All mutations	P	1.9849151477058453	>1
692	R	S	All mutations	S	1.0150848522941547	1
692	R	L	All mutations	L	1.9849151477058453	>1
692	R	K	All mutations	K	1.0150848522941547	1
692	R	D	All mutations	D	3.0	>1
692	R	Y	All mutations	Y	3.0	>1
692	R	H	All mutations	H	2.9849151477058453	>1
692	R	A	All mutations	A	2.0	>1
692	R	V	All mutations	V	2.0	>1
692	R	G	All mutations	G	1.0	1
692	R	E	All mutations	E	2.0	>1
692	R	M	All mutations	M	1.7749842866121937	>1
692	R	T	All mutations	T	1.0150848522941547	1
692	R	W	All mutations	W	1.759899434318039	>1
692	R	F	All mutations	F	3.0	>1
692	R	R	All mutations	R	0.0	0
692	R	N	All mutations	N	2.0150848522941547	>1
692	R	C	All mutations	C	2.0	>1
693	G	D	All mutations	D	1.9805153991200504	>1
693	G	K	All mutations	K	2.0194846008799496	>1
693	G	M	All mutations	M	2.800754242614708	>1
693	G	E	All mutations	E	1.0194846008799496	1
693	G	G	All mutations	G	0.0	0
693	G	S	All mutations	S	1.9805153991200504	>1
693	G	Y	All mutations	Y	2.9805153991200504	>1
693	G	R	All mutations	R	1.0	1
693	G	T	All mutations	T	2.0	>1
693	G	L	All mutations	L	2.0	>1
693	G	C	All mutations	C	1.9805153991200504	>1
693	G	N	All mutations	N	2.9805153991200504	>1
693	G	Q	All mutations	Q	2.0194846008799496	>1
693	G	F	All mutations	F	2.9805153991200504	>1
693	G	A	All mutations	A	1.0	1
693	G	W	All mutations	W	1.8007542426147076	>1
693	G	P	All mutations	P	2.0	>1
693	G	I	All mutations	I	2.199245757385292	>1
693	G	V	All mutations	V	1.0	1
693	G	H	All mutations	H	2.9805153991200504	>1
694	F	R	All mutations	R	1.9987429289754872	>1
694	F	Y	All mutations	Y	1.0012570710245128	1
694	F	H	All mutations	H	1.9987429289754872	>1
694	F	I	All mutations	I	1.0	1
694	F	M	All mutations	M	2.0	>1
694	F	A	All mutations	A	2.0	>1
694	F	G	All mutations	G	2.0	>1
694	F	K	All mutations	K	3.0	>1
694	F	E	All mutations	E	3.0	>1
694	F	S	All mutations	S	1.0012570710245128	1
694	F	D	All mutations	D	2.0	>1
694	F	C	All mutations	C	1.0012570710245128	1
694	F	L	All mutations	L	0.9987429289754871	1
694	F	V	All mutations	V	1.0	1
694	F	N	All mutations	N	2.0	>1
694	F	Q	All mutations	Q	2.998742928975487	>1
694	F	F	All mutations	F	0.001257071024512885	1
694	F	W	All mutations	W	2.001257071024513	>1
694	F	T	All mutations	T	2.0	>1
694	F	P	All mutations	P	1.9987429289754872	>1
695	L	I	All mutations	I	1.133249528598366	>1
695	L	L	All mutations	L	0.0006285355122564425	1
695	L	A	All mutations	A	1.9993714644877436	>1
695	L	P	All mutations	P	1.0238843494657448	1
695	L	E	All mutations	E	2.455688246385921	>1
695	L	F	All mutations	F	1.5204274041483343	>1
695	L	W	All mutations	W	2.843494657448146	>1
695	L	S	All mutations	S	1.9767441860465116	>1
695	L	N	All mutations	N	2.543683218101823	>1
695	L	T	All mutations	T	2.0	>1
695	L	M	All mutations	M	1.866750471401634	>1
695	L	G	All mutations	G	1.9993714644877436	>1
695	L	D	All mutations	D	2.5430546825895664	>1
695	L	R	All mutations	R	1.0238843494657448	1
695	L	Q	All mutations	Q	1.480201131363922	>1
695	L	Y	All mutations	Y	2.5204274041483345	>1
695	L	C	All mutations	C	2.5204274041483345	>1
695	L	H	All mutations	H	1.5675675675675675	>1
695	L	K	All mutations	K	2.456316781898177	>1
695	L	V	All mutations	V	0.9993714644877436	1
696	I	V	All mutations	V	1.0	1
696	I	S	All mutations	S	1.0018856065367694	1
696	I	D	All mutations	D	2.0018856065367694	>1
696	I	K	All mutations	K	1.9981143934632306	>1
696	I	G	All mutations	G	2.0	>1
696	I	W	All mutations	W	3.0	>1
696	I	T	All mutations	T	1.0	1
696	I	M	All mutations	M	1.0	1
696	I	Y	All mutations	Y	2.0018856065367694	>1
696	I	C	All mutations	C	2.0018856065367694	>1
696	I	H	All mutations	H	2.0018856065367694	>1
696	I	A	All mutations	A	2.0	>1
696	I	N	All mutations	N	1.0018856065367694	1
696	I	L	All mutations	L	1.0	1
696	I	F	All mutations	F	1.0018856065367694	1
696	I	I	All mutations	I	0.0	0
696	I	E	All mutations	E	2.9981143934632306	>1
696	I	R	All mutations	R	1.9981143934632306	>1
696	I	Q	All mutations	Q	2.9981143934632306	>1
696	I	P	All mutations	P	2.0	>1
697	L	Q	All mutations	Q	1.436203645505971	>1
697	L	N	All mutations	N	2.9937146448774357	>1
697	L	I	All mutations	I	1.7724701445631679	>1
697	L	A	All mutations	A	2.0	>1
697	L	T	All mutations	T	1.9993714644877436	>1
697	L	G	All mutations	G	2.0	>1
697	L	E	All mutations	E	2.005656819610308	>1
697	L	R	All mutations	R	1.4299182903834067	>1
697	L	M	All mutations	M	1.2262727844123193	>1
697	L	K	All mutations	K	2.0050282840980516	>1
697	L	L	All mutations	L	0.0006285355122564425	1
697	L	P	All mutations	P	1.430546825895663	>1
697	L	V	All mutations	V	1.0	1
697	L	H	All mutations	H	2.4248900062853553	>1
697	L	S	All mutations	S	1.5700817096165933	>1
697	L	Y	All mutations	Y	2.5644248900062854	>1
697	L	F	All mutations	F	1.5644248900062854	>1
697	L	C	All mutations	C	2.5644248900062854	>1
697	L	W	All mutations	W	1.796983029541169	>1
697	L	D	All mutations	D	2.994343180389692	>1
698	G	N	All mutations	N	2.0150848522941547	>1
698	G	C	All mutations	C	1.0150848522941547	1
698	G	A	All mutations	A	1.0	1
698	G	R	All mutations	R	1.0	1
698	G	M	All mutations	M	2.995600251414205	>1
698	G	Q	All mutations	Q	2.9849151477058453	>1
698	G	Y	All mutations	Y	2.0150848522941547	>1
698	G	T	All mutations	T	2.0	>1
698	G	H	All mutations	H	2.0150848522941547	>1
698	G	V	All mutations	V	1.0	1
698	G	I	All mutations	I	2.004399748585795	>1
698	G	D	All mutations	D	1.0150848522941547	1
698	G	L	All mutations	L	2.0	>1
698	G	K	All mutations	K	2.9849151477058453	>1
698	G	G	All mutations	G	0.0	0
698	G	E	All mutations	E	1.9849151477058453	>1
698	G	S	All mutations	S	1.0150848522941547	1
698	G	P	All mutations	P	2.0	>1
698	G	W	All mutations	W	1.9956002514142048	>1
698	G	F	All mutations	F	2.0150848522941547	>1
699	K	A	All mutations	A	2.0	>1
699	K	C	All mutations	C	2.9981143934632306	>1
699	K	S	All mutations	S	1.9981143934632306	>1
699	K	H	All mutations	H	2.0006285355122566	>1
699	K	P	All mutations	P	2.0	>1
699	K	F	All mutations	F	2.9993714644877434	>1
699	K	D	All mutations	D	2.0006285355122566	>1
699	K	Q	All mutations	Q	1.0018856065367694	1
699	K	N	All mutations	N	1.0006285355122564	1
699	K	V	All mutations	V	2.0	>1
699	K	K	All mutations	K	0.0018856065367693275	1
699	K	T	All mutations	T	1.0	1
699	K	M	All mutations	M	1.765556253928347	>1
699	K	L	All mutations	L	2.0	>1
699	K	R	All mutations	R	0.9993714644877436	1
699	K	E	All mutations	E	1.0018856065367694	1
699	K	G	All mutations	G	1.9987429289754872	>1
699	K	W	All mutations	W	2.764299182903834	>1
699	K	Y	All mutations	Y	2.0006285355122566	>1
699	K	I	All mutations	I	1.234443746071653	>1
700	E	L	All mutations	L	2.0	>1
700	E	W	All mutations	W	2.772470144563168	>1
700	E	K	All mutations	K	1.0	1
700	E	G	All mutations	G	1.0	1
700	E	A	All mutations	A	1.0	1
700	E	E	All mutations	E	0.0	0
700	E	I	All mutations	I	2.227529855436832	>1
700	E	S	All mutations	S	2.0	>1
700	E	N	All mutations	N	2.0	>1
700	E	T	All mutations	T	2.0	>1
700	E	P	All mutations	P	2.0	>1
700	E	Y	All mutations	Y	2.0	>1
700	E	V	All mutations	V	1.0	1
700	E	M	All mutations	M	2.772470144563168	>1
700	E	F	All mutations	F	3.0	>1
700	E	Q	All mutations	Q	1.0	1
700	E	C	All mutations	C	3.0	>1
700	E	H	All mutations	H	2.0	>1
700	E	R	All mutations	R	2.0	>1
700	E	D	All mutations	D	1.0	1
701	D	P	All mutations	P	2.0	>1
701	D	L	All mutations	L	2.0	>1
701	D	S	All mutations	S	1.9987429289754872	>1
701	D	F	All mutations	F	2.0	>1
701	D	I	All mutations	I	1.9987429289754872	>1
701	D	G	All mutations	G	1.0012570710245128	1
701	D	W	All mutations	W	3.0	>1
701	D	N	All mutations	N	0.9987429289754871	1
701	D	T	All mutations	T	1.9987429289754872	>1
701	D	Y	All mutations	Y	1.0	1
701	D	V	All mutations	V	1.0012570710245128	1
701	D	M	All mutations	M	2.998742928975487	>1
701	D	C	All mutations	C	2.0	>1
701	D	H	All mutations	H	1.0	1
701	D	D	All mutations	D	0.001257071024512885	1
701	D	E	All mutations	E	1.0012570710245128	1
701	D	A	All mutations	A	1.0012570710245128	1
701	D	K	All mutations	K	1.9987429289754872	>1
701	D	Q	All mutations	Q	2.0	>1
701	D	R	All mutations	R	2.0	>1
702	K	K	All mutations	K	0.1049654305468259	1
702	K	S	All mutations	S	1.896291640477687	>1
702	K	I	All mutations	I	1.589566310496543	>1
702	K	P	All mutations	P	1.9987429289754872	>1
702	K	N	All mutations	N	1.104965430546826	>1
702	K	T	All mutations	T	1.0012570710245128	1
702	K	Y	All mutations	Y	2.103708359522313	>1
702	K	G	All mutations	G	1.896291640477687	>1
702	K	F	All mutations	F	3.0	>1
702	K	Q	All mutations	Q	1.1024512884978002	>1
702	K	R	All mutations	R	0.896291640477687	1
702	K	E	All mutations	E	1.103708359522313	>1
702	K	W	All mutations	W	2.3079824010056567	>1
702	K	V	All mutations	V	2.0	>1
702	K	M	All mutations	M	1.4129478315524828	>1
702	K	L	All mutations	L	1.9987429289754872	>1
702	K	D	All mutations	D	2.103708359522313	>1
702	K	H	All mutations	H	2.1024512884978	>1
702	K	C	All mutations	C	2.896291640477687	>1
702	K	A	All mutations	A	2.0	>1
703	R	I	All mutations	I	1.0546825895663106	1
703	R	H	All mutations	H	2.989943431803897	>1
703	R	W	All mutations	W	1.9553739786297926	>1
703	R	Q	All mutations	Q	1.9899434318038969	>1
703	R	P	All mutations	P	1.9905719673161533	>1
703	R	N	All mutations	N	2.0087994971715903	>1
703	R	R	All mutations	R	0.0006285355122564425	1
703	R	K	All mutations	K	1.0087994971715901	1
703	R	T	All mutations	T	1.0094280326838467	1
703	R	E	All mutations	E	1.9993714644877436	>1
703	R	L	All mutations	L	1.9905719673161533	>1
703	R	Y	All mutations	Y	2.9993714644877434	>1
703	R	G	All mutations	G	1.0006285355122564	1
703	R	C	All mutations	C	2.0006285355122566	>1
703	R	S	All mutations	S	1.0100565681961031	1
703	R	F	All mutations	F	3.0	>1
703	R	D	All mutations	D	2.9993714644877434	>1
703	R	M	All mutations	M	1.9641734758013827	>1
703	R	A	All mutations	A	2.0	>1
703	R	V	All mutations	V	2.0	>1
704	Y	G	All mutations	G	1.9993714644877436	>1
704	Y	D	All mutations	D	1.0025141420490258	1
704	Y	R	All mutations	R	1.9993714644877436	>1
704	Y	N	All mutations	N	1.0025141420490258	1
704	Y	K	All mutations	K	2.0025141420490256	>1
704	Y	T	All mutations	T	2.0	>1
704	Y	Y	All mutations	Y	0.00251414204902577	1
704	Y	V	All mutations	V	1.9981143934632306	>1
704	Y	M	All mutations	M	2.9981143934632306	>1
704	Y	C	All mutations	C	0.9993714644877436	1
704	Y	A	All mutations	A	2.0	>1
704	Y	H	All mutations	H	1.0025141420490258	1
704	Y	I	All mutations	I	1.9981143934632306	>1
704	Y	L	All mutations	L	1.9981143934632306	>1
704	Y	W	All mutations	W	1.9993714644877436	>1
704	Y	E	All mutations	E	2.0025141420490256	>1
704	Y	F	All mutations	F	0.9981143934632307	1
704	Y	S	All mutations	S	1.0	1
704	Y	Q	All mutations	Q	2.0025141420490256	>1
704	Y	P	All mutations	P	2.0	>1
705	G	P	All mutations	P	2.0	>1
705	G	W	All mutations	W	1.7844123192960402	>1
705	G	S	All mutations	S	1.5430546825895664	>1
705	G	I	All mutations	I	2.2155876807039596	>1
705	G	Q	All mutations	Q	2.4569453174104336	>1
705	G	N	All mutations	N	2.5430546825895664	>1
705	G	K	All mutations	K	2.4569453174104336	>1
705	G	T	All mutations	T	2.0	>1
705	G	Y	All mutations	Y	2.5430546825895664	>1
705	G	V	All mutations	V	1.0	1
705	G	F	All mutations	F	2.5430546825895664	>1
705	G	E	All mutations	E	1.4569453174104336	>1
705	G	M	All mutations	M	2.7844123192960404	>1
705	G	C	All mutations	C	1.5430546825895664	>1
705	G	R	All mutations	R	1.0	1
705	G	H	All mutations	H	2.5430546825895664	>1
705	G	A	All mutations	A	1.0	1
705	G	D	All mutations	D	1.5430546825895664	>1
705	G	G	All mutations	G	0.0	0
705	G	L	All mutations	L	2.0	>1
706	P	L	All mutations	L	1.0	1
706	P	V	All mutations	V	2.0	>1
706	P	T	All mutations	T	1.0	1
706	P	D	All mutations	D	2.9629164047768697	>1
706	P	P	All mutations	P	0.0	0
706	P	K	All mutations	K	2.0370835952231303	>1
706	P	A	All mutations	A	1.0	1
706	P	E	All mutations	E	2.0370835952231303	>1
706	P	N	All mutations	N	2.9629164047768697	>1
706	P	F	All mutations	F	2.9629164047768697	>1
706	P	M	All mutations	M	2.972972972972973	>1
706	P	Q	All mutations	Q	1.03708359522313	1
706	P	H	All mutations	H	1.96291640477687	>1
706	P	Y	All mutations	Y	2.9629164047768697	>1
706	P	G	All mutations	G	2.0	>1
706	P	R	All mutations	R	1.0	1
706	P	I	All mutations	I	2.027027027027027	>1
706	P	C	All mutations	C	2.9629164047768697	>1
706	P	S	All mutations	S	1.0	1
706	P	W	All mutations	W	2.972972972972973	>1
707	A	W	All mutations	W	2.9679446888749212	>1
707	A	Q	All mutations	Q	2.0	>1
707	A	T	All mutations	T	1.0	1
707	A	D	All mutations	D	2.0119421747328725	>1
707	A	V	All mutations	V	1.0138277812696417	1
707	A	L	All mutations	L	1.985543683218102	>1
707	A	P	All mutations	P	0.9981143934632307	1
707	A	A	All mutations	A	0.01508485229415462	1
707	A	S	All mutations	S	0.9893148962916405	1
707	A	E	All mutations	E	1.0169704588309239	1
707	A	C	All mutations	C	2.986172218730358	>1
707	A	N	All mutations	N	2.996857322438718	>1
707	A	Y	All mutations	Y	2.986172218730358	>1
707	A	K	All mutations	K	2.0018856065367694	>1
707	A	M	All mutations	M	2.9780012570710244	>1
707	A	H	All mutations	H	2.9949717159019484	>1
707	A	F	All mutations	F	2.985543683218102	>1
707	A	I	All mutations	I	2.0194846008799496	>1
707	A	G	All mutations	G	1.014456316781898	1
707	A	R	All mutations	R	1.9968573224387178	>1
708	L	V	All mutations	V	1.0	1
708	L	M	All mutations	M	1.1414204902576996	>1
708	L	A	All mutations	A	2.0	>1
708	L	C	All mutations	C	2.363293526084224	>1
708	L	Y	All mutations	Y	2.363293526084224	>1
708	L	E	All mutations	E	2.0	>1
708	L	T	All mutations	T	2.0	>1
708	L	L	All mutations	L	0.0	0
708	L	F	All mutations	F	1.3632935260842238	>1
708	L	W	All mutations	W	1.5047140163419233	>1
708	L	S	All mutations	S	1.3632935260842238	>1
708	L	I	All mutations	I	1.8585795097423004	>1
708	L	K	All mutations	K	2.0	>1
708	L	D	All mutations	D	3.0	>1
708	L	Q	All mutations	Q	1.6367064739157762	>1
708	L	H	All mutations	H	2.636706473915776	>1
708	L	P	All mutations	P	1.6367064739157762	>1
708	L	N	All mutations	N	3.0	>1
708	L	R	All mutations	R	1.6367064739157762	>1
708	L	G	All mutations	G	2.0	>1
709	S	W	All mutations	W	2.0	>1
709	S	V	All mutations	V	2.0	>1
709	S	F	All mutations	F	2.0	>1
709	S	K	All mutations	K	2.0	>1
709	S	I	All mutations	I	1.0	1
709	S	C	All mutations	C	1.0	1
709	S	R	All mutations	R	1.0	1
709	S	Y	All mutations	Y	2.0	>1
709	S	A	All mutations	A	2.0	>1
709	S	P	All mutations	P	2.0	>1
709	S	S	All mutations	S	0.0	0
709	S	T	All mutations	T	1.0	1
709	S	N	All mutations	N	1.0	1
709	S	H	All mutations	H	2.0	>1
709	S	Q	All mutations	Q	3.0	>1
709	S	D	All mutations	D	2.0	>1
709	S	E	All mutations	E	3.0	>1
709	S	L	All mutations	L	2.0	>1
709	S	M	All mutations	M	2.0	>1
709	S	G	All mutations	G	1.0	1
710	I	R	All mutations	R	1.9962287869264614	>1
710	I	P	All mutations	P	2.0	>1
710	I	C	All mutations	C	2.003771213073539	>1
710	I	Y	All mutations	Y	2.003771213073539	>1
710	I	F	All mutations	F	1.0037712130735386	1
710	I	T	All mutations	T	1.0	1
710	I	N	All mutations	N	1.0037712130735386	1
710	I	K	All mutations	K	1.9962287869264614	>1
710	I	G	All mutations	G	2.0	>1
710	I	S	All mutations	S	1.0037712130735386	1
710	I	Q	All mutations	Q	2.996228786926461	>1
710	I	D	All mutations	D	2.003771213073539	>1
710	I	E	All mutations	E	2.996228786926461	>1
710	I	H	All mutations	H	2.003771213073539	>1
710	I	W	All mutations	W	3.0	>1
710	I	M	All mutations	M	1.0	1
710	I	A	All mutations	A	2.0	>1
710	I	V	All mutations	V	1.0	1
710	I	L	All mutations	L	1.0	1
710	I	I	All mutations	I	0.0	0
711	N	N	All mutations	N	0.003771213073538655	1
711	N	M	All mutations	M	2.0006285355122566	>1
711	N	H	All mutations	H	1.0031426775612822	1
711	N	G	All mutations	G	1.9962287869264614	>1
711	N	R	All mutations	R	1.9968573224387178	>1
711	N	C	All mutations	C	1.9968573224387178	>1
711	N	W	All mutations	W	2.996857322438718	>1
711	N	S	All mutations	S	0.9974858579509742	1
711	N	F	All mutations	F	2.0	>1
711	N	P	All mutations	P	2.0	>1
711	N	T	All mutations	T	1.0006285355122564	1
711	N	E	All mutations	E	2.0025141420490256	>1
711	N	Q	All mutations	Q	2.003142677561282	>1
711	N	L	All mutations	L	2.0	>1
711	N	A	All mutations	A	1.9993714644877436	>1
711	N	K	All mutations	K	1.0037712130735386	1
711	N	I	All mutations	I	1.0006285355122564	1
711	N	Y	All mutations	Y	1.0031426775612822	1
711	N	D	All mutations	D	1.0025141420490258	1
711	N	V	All mutations	V	1.9993714644877436	>1
712	E	G	All mutations	G	1.0	1
712	E	M	All mutations	M	2.4764299182903833	>1
712	E	Y	All mutations	Y	2.0	>1
712	E	C	All mutations	C	3.0	>1
712	E	S	All mutations	S	2.0	>1
712	E	W	All mutations	W	2.4764299182903833	>1
712	E	I	All mutations	I	2.5235700817096167	>1
712	E	L	All mutations	L	2.0	>1
712	E	P	All mutations	P	2.0	>1
712	E	V	All mutations	V	1.0	1
712	E	E	All mutations	E	0.0	0
712	E	N	All mutations	N	2.0	>1
712	E	A	All mutations	A	1.0	1
712	E	T	All mutations	T	2.0	>1
712	E	R	All mutations	R	2.0	>1
712	E	Q	All mutations	Q	1.0	1
712	E	F	All mutations	F	3.0	>1
712	E	K	All mutations	K	1.0	1
712	E	H	All mutations	H	2.0	>1
712	E	D	All mutations	D	1.0	1
713	L	L	All mutations	L	0.0	0
713	L	W	All mutations	W	1.6737900691389063	>1
713	L	F	All mutations	F	1.6423632935260841	>1
713	L	E	All mutations	E	2.0	>1
713	L	V	All mutations	V	1.0	1
713	L	T	All mutations	T	2.0	>1
713	L	I	All mutations	I	1.9685732243871779	>1
713	L	R	All mutations	R	1.3576367064739159	>1
713	L	Y	All mutations	Y	2.6423632935260843	>1
713	L	A	All mutations	A	2.0	>1
713	L	D	All mutations	D	3.0	>1
713	L	S	All mutations	S	1.6423632935260841	>1
713	L	Q	All mutations	Q	1.3576367064739159	>1
713	L	C	All mutations	C	2.6423632935260843	>1
713	L	G	All mutations	G	2.0	>1
713	L	K	All mutations	K	2.0	>1
713	L	N	All mutations	N	3.0	>1
713	L	H	All mutations	H	2.3576367064739157	>1
713	L	M	All mutations	M	1.0314267756128221	1
713	L	P	All mutations	P	1.3576367064739159	>1
714	S	L	All mutations	L	2.0	>1
714	S	A	All mutations	A	1.9924575738529227	>1
714	S	K	All mutations	K	2.0081709616593337	>1
714	S	Y	All mutations	Y	1.9993714644877436	>1
714	S	D	All mutations	D	1.9924575738529227	>1
714	S	G	All mutations	G	0.9924575738529227	1
714	S	W	All mutations	W	1.9993714644877436	>1
714	S	R	All mutations	R	1.0	1
714	S	P	All mutations	P	2.0	>1
714	S	H	All mutations	H	2.0	>1
714	S	T	All mutations	T	1.0081709616593337	1
714	S	V	All mutations	V	1.9924575738529227	>1
714	S	C	All mutations	C	0.9993714644877436	1
714	S	N	All mutations	N	1.0081709616593337	1
714	S	E	All mutations	E	2.992457573852923	>1
714	S	Q	All mutations	Q	3.0	>1
714	S	F	All mutations	F	1.9993714644877436	>1
714	S	S	All mutations	S	0.008170961659333752	1
714	S	M	All mutations	M	2.0081709616593337	>1
714	S	I	All mutations	I	1.0081709616593337	1
715	N	N	All mutations	N	0.0043997485857950975	1
715	N	D	All mutations	D	1.0043997485857952	1
715	N	T	All mutations	T	0.9987429289754871	1
715	N	L	All mutations	L	2.0	>1
715	N	V	All mutations	V	2.0	>1
715	N	S	All mutations	S	0.9968573224387178	1
715	N	H	All mutations	H	1.0043997485857952	1
715	N	Y	All mutations	Y	1.0043997485857952	1
715	N	W	All mutations	W	2.996857322438718	>1
715	N	M	All mutations	M	2.0	>1
715	N	C	All mutations	C	1.9968573224387178	>1
715	N	K	All mutations	K	1.0043997485857952	1
715	N	P	All mutations	P	1.9987429289754872	>1
715	N	Q	All mutations	Q	2.004399748585795	>1
715	N	G	All mutations	G	1.9968573224387178	>1
715	N	F	All mutations	F	2.0	>1
715	N	R	All mutations	R	1.9968573224387178	>1
715	N	I	All mutations	I	1.0	1
715	N	A	All mutations	A	1.9987429289754872	>1
715	N	E	All mutations	E	2.004399748585795	>1
716	L	H	All mutations	H	1.0	1
716	L	G	All mutations	G	2.0	>1
716	L	F	All mutations	F	1.0	1
716	L	R	All mutations	R	1.0	1
716	L	T	All mutations	T	2.0	>1
716	L	K	All mutations	K	3.0	>1
716	L	Q	All mutations	Q	2.0	>1
716	L	A	All mutations	A	2.0	>1
716	L	Y	All mutations	Y	2.0	>1
716	L	W	All mutations	W	3.0	>1
716	L	D	All mutations	D	2.0	>1
716	L	N	All mutations	N	2.0	>1
716	L	S	All mutations	S	2.0	>1
716	L	M	All mutations	M	2.0	>1
716	L	C	All mutations	C	2.0	>1
716	L	L	All mutations	L	0.0	0
716	L	E	All mutations	E	3.0	>1
716	L	P	All mutations	P	1.0	1
716	L	I	All mutations	I	1.0	1
716	L	V	All mutations	V	1.0	1
717	A	Q	All mutations	Q	2.0886235072281583	>1
717	A	W	All mutations	W	2.664990571967316	>1
717	A	Y	All mutations	Y	2.910747957259585	>1
717	A	N	All mutations	N	2.903834066624764	>1
717	A	G	All mutations	G	1.0081709616593337	1
717	A	R	All mutations	R	1.993086109365179	>1
717	A	D	All mutations	D	1.9195474544311755	>1
717	A	F	All mutations	F	2.9082338152105596	>1
717	A	K	All mutations	K	2.081081081081081	>1
717	A	E	All mutations	E	1.0967944688874922	1
717	A	C	All mutations	C	2.910747957259585	>1
717	A	V	All mutations	V	1.005656819610308	1
717	A	M	All mutations	M	2.6555625392834696	>1
717	A	P	All mutations	P	1.0025141420490258	1
717	A	S	All mutations	S	1.0018856065367694	1
717	A	H	All mutations	H	2.9113764927718417	>1
717	A	L	All mutations	L	1.9968573224387178	>1
717	A	A	All mutations	A	0.010685103708359522	1
717	A	T	All mutations	T	0.9949717159019484	1
717	A	I	All mutations	I	2.324324324324324	>1
718	K	L	All mutations	L	2.0	>1
718	K	Y	All mutations	Y	2.007542426147077	>1
718	K	E	All mutations	E	1.0075424261470773	1
718	K	C	All mutations	C	2.992457573852923	>1
718	K	A	All mutations	A	2.0	>1
718	K	R	All mutations	R	0.9924575738529227	1
718	K	M	All mutations	M	1.5788812067881834	>1
718	K	W	All mutations	W	2.5713387806411063	>1
718	K	T	All mutations	T	1.0	1
718	K	P	All mutations	P	2.0	>1
718	K	D	All mutations	D	2.007542426147077	>1
718	K	G	All mutations	G	1.9924575738529227	>1
718	K	K	All mutations	K	0.00754242614707731	1
718	K	I	All mutations	I	1.4211187932118166	>1
718	K	V	All mutations	V	2.0	>1
718	K	S	All mutations	S	1.9924575738529227	>1
718	K	Q	All mutations	Q	1.0075424261470773	1
718	K	N	All mutations	N	1.0075424261470773	1
718	K	F	All mutations	F	3.0	>1
718	K	H	All mutations	H	2.007542426147077	>1
719	G	Y	All mutations	Y	3.0	>1
719	G	H	All mutations	H	3.0	>1
719	G	G	All mutations	G	0.0	0
719	G	P	All mutations	P	2.0	>1
719	G	F	All mutations	F	3.0	>1
719	G	M	All mutations	M	2.490886235072282	>1
719	G	W	All mutations	W	1.4908862350722816	>1
719	G	C	All mutations	C	2.0	>1
719	G	I	All mutations	I	2.509113764927718	>1
719	G	D	All mutations	D	2.0	>1
719	G	A	All mutations	A	1.0	1
719	G	S	All mutations	S	2.0	>1
719	G	N	All mutations	N	3.0	>1
719	G	Q	All mutations	Q	2.0	>1
719	G	L	All mutations	L	2.0	>1
719	G	V	All mutations	V	1.0	1
719	G	T	All mutations	T	2.0	>1
719	G	E	All mutations	E	1.0	1
719	G	R	All mutations	R	1.0	1
719	G	K	All mutations	K	2.0	>1
720	E	G	All mutations	G	1.0	1
720	E	I	All mutations	I	2.863607793840352	>1
720	E	E	All mutations	E	0.0	0
720	E	F	All mutations	F	3.0	>1
720	E	Q	All mutations	Q	1.0	1
720	E	H	All mutations	H	2.0	>1
720	E	V	All mutations	V	1.0	1
720	E	D	All mutations	D	1.0	1
720	E	T	All mutations	T	2.0	>1
720	E	K	All mutations	K	1.0	1
720	E	S	All mutations	S	2.0	>1
720	E	Y	All mutations	Y	2.0	>1
720	E	P	All mutations	P	2.0	>1
720	E	N	All mutations	N	2.0	>1
720	E	M	All mutations	M	2.136392206159648	>1
720	E	W	All mutations	W	2.136392206159648	>1
720	E	L	All mutations	L	2.0	>1
720	E	A	All mutations	A	1.0	1
720	E	R	All mutations	R	2.0	>1
720	E	C	All mutations	C	3.0	>1
721	K	D	All mutations	D	2.0006285355122566	>1
721	K	E	All mutations	E	1.0018856065367694	1
721	K	L	All mutations	L	2.0	>1
721	K	S	All mutations	S	1.9981143934632306	>1
721	K	Y	All mutations	Y	2.0006285355122566	>1
721	K	F	All mutations	F	2.9993714644877434	>1
721	K	P	All mutations	P	2.0	>1
721	K	A	All mutations	A	2.0	>1
721	K	G	All mutations	G	1.9987429289754872	>1
721	K	R	All mutations	R	0.9993714644877436	1
721	K	T	All mutations	T	1.0	1
721	K	Q	All mutations	Q	1.0018856065367694	1
721	K	N	All mutations	N	1.0006285355122564	1
721	K	W	All mutations	W	2.223130106851037	>1
721	K	C	All mutations	C	2.9981143934632306	>1
721	K	V	All mutations	V	2.0	>1
721	K	I	All mutations	I	1.77561282212445	>1
721	K	K	All mutations	K	0.0018856065367693275	1
721	K	H	All mutations	H	2.0006285355122566	>1
721	K	M	All mutations	M	1.22438717787555	>1
722	A	R	All mutations	R	2.0	>1
722	A	M	All mutations	M	2.9993714644877434	>1
722	A	W	All mutations	W	3.0	>1
722	A	N	All mutations	N	2.0050282840980516	>1
722	A	L	All mutations	L	1.9993714644877436	>1
722	A	Q	All mutations	Q	2.9949717159019484	>1
722	A	V	All mutations	V	0.9993714644877436	1
722	A	Y	All mutations	Y	2.0050282840980516	>1
722	A	P	All mutations	P	1.0006285355122564	1
722	A	E	All mutations	E	1.9949717159019484	>1
722	A	D	All mutations	D	1.0050282840980516	1
722	A	K	All mutations	K	2.9949717159019484	>1
722	A	A	All mutations	A	0.0006285355122564425	1
722	A	H	All mutations	H	2.0050282840980516	>1
722	A	T	All mutations	T	1.0006285355122564	1
722	A	I	All mutations	I	1.9993714644877436	>1
722	A	C	All mutations	C	2.0050282840980516	>1
722	A	S	All mutations	S	1.0006285355122564	1
722	A	F	All mutations	F	2.004399748585795	>1
722	A	G	All mutations	G	1.0	1
723	N	N	All mutations	N	0.0	0
723	N	D	All mutations	D	1.0	1
723	N	F	All mutations	F	2.0	>1
723	N	K	All mutations	K	1.0	1
723	N	R	All mutations	R	2.0	>1
723	N	Q	All mutations	Q	2.0	>1
723	N	V	All mutations	V	2.0	>1
723	N	I	All mutations	I	1.0	1
723	N	M	All mutations	M	2.0	>1
723	N	S	All mutations	S	1.0	1
723	N	Y	All mutations	Y	1.0	1
723	N	W	All mutations	W	3.0	>1
723	N	L	All mutations	L	2.0	>1
723	N	A	All mutations	A	2.0	>1
723	N	H	All mutations	H	1.0	1
723	N	T	All mutations	T	1.0	1
723	N	C	All mutations	C	2.0	>1
723	N	G	All mutations	G	2.0	>1
723	N	P	All mutations	P	2.0	>1
723	N	E	All mutations	E	2.0	>1
724	V	H	All mutations	H	2.9874292897548713	>1
724	V	R	All mutations	R	2.0	>1
724	V	D	All mutations	D	1.987429289754871	>1
724	V	K	All mutations	K	2.0125707102451287	>1
724	V	S	All mutations	S	2.0	>1
724	V	F	All mutations	F	1.987429289754871	>1
724	V	E	All mutations	E	1.012570710245129	1
724	V	L	All mutations	L	1.0	1
724	V	Q	All mutations	Q	2.0125707102451287	>1
724	V	W	All mutations	W	2.0320553111250788	>1
724	V	M	All mutations	M	1.0320553111250785	1
724	V	Y	All mutations	Y	2.9874292897548713	>1
724	V	G	All mutations	G	1.0	1
724	V	V	All mutations	V	0.0	0
724	V	P	All mutations	P	2.0	>1
724	V	C	All mutations	C	2.9874292897548713	>1
724	V	T	All mutations	T	2.0	>1
724	V	I	All mutations	I	1.9679446888749215	>1
724	V	A	All mutations	A	1.0	1
724	V	N	All mutations	N	2.9874292897548713	>1
725	L	P	All mutations	P	1.3890634820867378	>1
725	L	G	All mutations	G	2.0	>1
725	L	E	All mutations	E	2.003142677561282	>1
725	L	I	All mutations	I	1.5191703331238215	>1
725	L	M	All mutations	M	1.4745443117536141	>1
725	L	K	All mutations	K	2.0	>1
725	L	V	All mutations	V	1.0	1
725	L	W	All mutations	W	2.0917661847894404	>1
725	L	F	All mutations	F	1.6109365179132622	>1
725	L	L	All mutations	L	0.0031426775612822125	1
725	L	Y	All mutations	Y	2.610936517913262	>1
725	L	R	All mutations	R	1.3859208045254556	>1
725	L	N	All mutations	N	2.9937146448774357	>1
725	L	H	All mutations	H	2.3859208045254556	>1
725	L	T	All mutations	T	1.9968573224387178	>1
725	L	D	All mutations	D	2.996857322438718	>1
725	L	Q	All mutations	Q	1.3922061596480202	>1
725	L	C	All mutations	C	2.610936517913262	>1
725	L	A	All mutations	A	2.0	>1
725	L	S	All mutations	S	1.6140791954745444	>1
726	I	S	All mutations	S	1.5386549340037712	>1
726	I	L	All mutations	L	1.0	1
726	I	C	All mutations	C	2.5386549340037714	>1
726	I	M	All mutations	M	1.0	1
726	I	P	All mutations	P	2.0	>1
726	I	K	All mutations	K	1.4613450659962288	>1
726	I	H	All mutations	H	2.5386549340037714	>1
726	I	A	All mutations	A	2.0	>1
726	I	R	All mutations	R	1.4613450659962288	>1
726	I	D	All mutations	D	2.5386549340037714	>1
726	I	V	All mutations	V	1.0	1
726	I	F	All mutations	F	1.5386549340037712	>1
726	I	E	All mutations	E	2.4613450659962286	>1
726	I	G	All mutations	G	2.0	>1
726	I	Y	All mutations	Y	2.5386549340037714	>1
726	I	Q	All mutations	Q	2.4613450659962286	>1
726	I	N	All mutations	N	1.5386549340037712	>1
726	I	T	All mutations	T	1.0	1
726	I	I	All mutations	I	0.0	0
726	I	W	All mutations	W	3.0	>1
727	G	C	All mutations	C	1.9893148962916405	>1
727	G	D	All mutations	D	1.9893148962916405	>1
727	G	T	All mutations	T	2.0	>1
727	G	P	All mutations	P	2.0	>1
727	G	V	All mutations	V	1.0	1
727	G	N	All mutations	N	2.9893148962916403	>1
727	G	W	All mutations	W	1.0232558139534884	1
727	G	L	All mutations	L	2.0	>1
727	G	G	All mutations	G	0.0	0
727	G	R	All mutations	R	1.0	1
727	G	M	All mutations	M	2.0232558139534884	>1
727	G	F	All mutations	F	2.9893148962916403	>1
727	G	E	All mutations	E	1.0106851037083595	1
727	G	K	All mutations	K	2.0106851037083597	>1
727	G	A	All mutations	A	1.0	1
727	G	S	All mutations	S	1.9893148962916405	>1
727	G	I	All mutations	I	2.9767441860465116	>1
727	G	Q	All mutations	Q	2.0106851037083597	>1
727	G	Y	All mutations	Y	2.9893148962916403	>1
727	G	H	All mutations	H	2.9893148962916403	>1
728	Q	W	All mutations	W	2.989943431803897	>1
728	Q	T	All mutations	T	2.0	>1
728	Q	A	All mutations	A	2.0	>1
728	Q	M	All mutations	M	2.989943431803897	>1
728	Q	I	All mutations	I	2.010056568196103	>1
728	Q	G	All mutations	G	2.0	>1
728	Q	P	All mutations	P	1.0	1
728	Q	V	All mutations	V	2.0	>1
728	Q	Y	All mutations	Y	2.0	>1
728	Q	N	All mutations	N	2.0	>1
728	Q	C	All mutations	C	3.0	>1
728	Q	D	All mutations	D	2.0	>1
728	Q	L	All mutations	L	1.0	1
728	Q	R	All mutations	R	1.0	1
728	Q	K	All mutations	K	1.0	1
728	Q	F	All mutations	F	3.0	>1
728	Q	S	All mutations	S	2.0	>1
728	Q	Q	All mutations	Q	0.0	0
728	Q	H	All mutations	H	1.0	1
728	Q	E	All mutations	E	1.0	1
729	G	H	All mutations	H	2.9993714644877434	>1
729	G	A	All mutations	A	1.0	1
729	G	F	All mutations	F	2.9993714644877434	>1
729	G	I	All mutations	I	2.005656819610308	>1
729	G	P	All mutations	P	2.0	>1
729	G	G	All mutations	G	0.0	0
729	G	N	All mutations	N	2.9993714644877434	>1
729	G	Y	All mutations	Y	2.9993714644877434	>1
729	G	V	All mutations	V	1.0	1
729	G	D	All mutations	D	1.9993714644877436	>1
729	G	R	All mutations	R	1.0	1
729	G	E	All mutations	E	1.0006285355122564	1
729	G	M	All mutations	M	2.994343180389692	>1
729	G	S	All mutations	S	1.9993714644877436	>1
729	G	T	All mutations	T	2.0	>1
729	G	Q	All mutations	Q	2.0006285355122566	>1
729	G	K	All mutations	K	2.0006285355122566	>1
729	G	L	All mutations	L	2.0	>1
729	G	C	All mutations	C	1.9993714644877436	>1
729	G	W	All mutations	W	1.994343180389692	>1
730	D	E	All mutations	E	1.0031426775612822	1
730	D	R	All mutations	R	1.9993714644877436	>1
730	D	Q	All mutations	Q	2.0006285355122566	>1
730	D	K	All mutations	K	1.9981143934632306	>1
730	D	A	All mutations	A	1.0025141420490258	1
730	D	I	All mutations	I	1.9974858579509742	>1
730	D	D	All mutations	D	0.0031426775612822125	1
730	D	T	All mutations	T	1.9974858579509742	>1
730	D	C	All mutations	C	1.9993714644877436	>1
730	D	M	All mutations	M	2.9974858579509744	>1
730	D	V	All mutations	V	1.0025141420490258	1
730	D	N	All mutations	N	0.9981143934632307	1
730	D	W	All mutations	W	2.9993714644877434	>1
730	D	Y	All mutations	Y	1.0006285355122564	1
730	D	G	All mutations	G	1.0018856065367694	1
730	D	F	All mutations	F	2.0	>1
730	D	P	All mutations	P	2.0	>1
730	D	L	All mutations	L	2.0	>1
730	D	H	All mutations	H	1.0006285355122564	1
730	D	S	All mutations	S	1.9968573224387178	>1
731	V	C	All mutations	C	2.9824010056568198	>1
731	V	R	All mutations	R	1.9924575738529227	>1
731	V	L	All mutations	L	1.0735386549340038	1
731	V	F	All mutations	F	2.05656819610308	>1
731	V	I	All mutations	I	1.8956631049654304	>1
731	V	G	All mutations	G	1.0081709616593337	1
731	V	E	All mutations	E	1.0251414204902578	1
731	V	Y	All mutations	Y	2.9824010056568198	>1
731	V	D	All mutations	D	1.9912005028284099	>1
731	V	K	All mutations	K	2.0094280326838465	>1
731	V	S	All mutations	S	1.9252042740414834	>1
731	V	P	All mutations	P	1.9258328095537398	>1
731	V	Q	All mutations	Q	2.016970458830924	>1
731	V	T	All mutations	T	1.9182903834066625	>1
731	V	V	All mutations	V	0.08233815210559396	1
731	V	W	All mutations	W	2.170333123821496	>1
731	V	M	All mutations	M	1.2375864236329353	>1
731	V	H	All mutations	H	2.983029541169076	>1
731	V	N	All mutations	N	2.975487115021999	>1
731	V	A	All mutations	A	0.9340037712130735	1
732	V	W	All mutations	W	2.0050282840980516	>1
732	V	E	All mutations	E	1.0006285355122564	1
732	V	H	All mutations	H	3.0	>1
732	V	G	All mutations	G	1.0006285355122564	1
732	V	F	All mutations	F	1.9993714644877436	>1
732	V	P	All mutations	P	2.0	>1
732	V	C	All mutations	C	2.9993714644877434	>1
732	V	K	All mutations	K	2.0	>1
732	V	R	All mutations	R	2.0	>1
732	V	Y	All mutations	Y	2.9993714644877434	>1
732	V	S	All mutations	S	1.9993714644877436	>1
732	V	A	All mutations	A	1.0006285355122564	1
732	V	T	All mutations	T	2.0	>1
732	V	L	All mutations	L	0.9993714644877436	1
732	V	D	All mutations	D	2.0006285355122566	>1
732	V	Q	All mutations	Q	2.0	>1
732	V	M	All mutations	M	1.005656819610308	1
732	V	N	All mutations	N	3.0	>1
732	V	I	All mutations	I	1.994343180389692	>1
732	V	V	All mutations	V	0.0006285355122564425	1
733	L	D	All mutations	D	3.0	>1
733	L	T	All mutations	T	2.0	>1
733	L	G	All mutations	G	2.0	>1
733	L	I	All mutations	I	1.9956002514142048	>1
733	L	Q	All mutations	Q	1.900691389063482	>1
733	L	N	All mutations	N	3.0	>1
733	L	Y	All mutations	Y	2.099308610936518	>1
733	L	W	All mutations	W	1.103708359522313	>1
733	L	V	All mutations	V	1.0	1
733	L	R	All mutations	R	1.900691389063482	>1
733	L	P	All mutations	P	1.900691389063482	>1
733	L	A	All mutations	A	2.0	>1
733	L	L	All mutations	L	0.0	0
733	L	E	All mutations	E	2.0	>1
733	L	K	All mutations	K	2.0	>1
733	L	S	All mutations	S	1.099308610936518	1
733	L	F	All mutations	F	1.099308610936518	1
733	L	H	All mutations	H	2.900691389063482	>1
733	L	C	All mutations	C	2.099308610936518	>1
733	L	M	All mutations	M	1.0043997485857952	1
734	V	M	All mutations	M	1.6429918290383407	>1
734	V	R	All mutations	R	2.0	>1
734	V	A	All mutations	A	1.0	1
734	V	S	All mutations	S	2.0	>1
734	V	Q	All mutations	Q	2.0163419233186675	>1
734	V	L	All mutations	L	1.0	1
734	V	I	All mutations	I	1.3570081709616593	>1
734	V	G	All mutations	G	1.0	1
734	V	C	All mutations	C	2.9836580766813325	>1
734	V	F	All mutations	F	1.9836580766813325	>1
734	V	K	All mutations	K	2.0163419233186675	>1
734	V	D	All mutations	D	1.9836580766813325	>1
734	V	V	All mutations	V	0.0	0
734	V	T	All mutations	T	2.0	>1
734	V	P	All mutations	P	2.0	>1
734	V	N	All mutations	N	2.9836580766813325	>1
734	V	H	All mutations	H	2.9836580766813325	>1
734	V	E	All mutations	E	1.0163419233186675	1
734	V	W	All mutations	W	2.6429918290383405	>1
734	V	Y	All mutations	Y	2.9836580766813325	>1
735	M	F	All mutations	F	2.0	>1
735	M	H	All mutations	H	2.994343180389692	>1
735	M	A	All mutations	A	2.0	>1
735	M	V	All mutations	V	1.0	1
735	M	P	All mutations	P	1.994343180389692	>1
735	M	W	All mutations	W	2.0	>1
735	M	S	All mutations	S	2.0	>1
735	M	L	All mutations	L	0.994343180389692	1
735	M	D	All mutations	D	3.0	>1
735	M	M	All mutations	M	0.0056568196103079825	1
735	M	K	All mutations	K	1.005656819610308	1
735	M	Y	All mutations	Y	3.0	>1
735	M	T	All mutations	T	1.005656819610308	1
735	M	N	All mutations	N	2.005656819610308	>1
735	M	E	All mutations	E	2.0	>1
735	M	C	All mutations	C	3.0	>1
735	M	G	All mutations	G	2.0	>1
735	M	Q	All mutations	Q	1.994343180389692	>1
735	M	I	All mutations	I	1.005656819610308	1
735	M	R	All mutations	R	1.0	1
736	K	T	All mutations	T	1.0	1
736	K	H	All mutations	H	2.0	>1
736	K	K	All mutations	K	0.0	0
736	K	Q	All mutations	Q	1.0	1
736	K	C	All mutations	C	3.0	>1
736	K	I	All mutations	I	1.0	1
736	K	M	All mutations	M	2.0	>1
736	K	V	All mutations	V	2.0	>1
736	K	R	All mutations	R	1.0	1
736	K	D	All mutations	D	2.0	>1
736	K	Y	All mutations	Y	2.0	>1
736	K	G	All mutations	G	2.0	>1
736	K	S	All mutations	S	2.0	>1
736	K	L	All mutations	L	2.0	>1
736	K	P	All mutations	P	2.0	>1
736	K	E	All mutations	E	1.0	1
736	K	F	All mutations	F	3.0	>1
736	K	A	All mutations	A	2.0	>1
736	K	N	All mutations	N	1.0	1
736	K	W	All mutations	W	3.0	>1
737	R	P	All mutations	P	1.0	1
737	R	T	All mutations	T	2.0	>1
737	R	A	All mutations	A	2.0	>1
737	R	S	All mutations	S	2.0	>1
737	R	Y	All mutations	Y	3.0	>1
737	R	H	All mutations	H	2.0	>1
737	R	D	All mutations	D	3.0	>1
737	R	C	All mutations	C	2.0	>1
737	R	M	All mutations	M	2.0339409176618477	>1
737	R	F	All mutations	F	3.0	>1
737	R	L	All mutations	L	1.0	1
737	R	V	All mutations	V	2.0	>1
737	R	R	All mutations	R	0.0	0
737	R	W	All mutations	W	1.033940917661848	1
737	R	K	All mutations	K	2.0	>1
737	R	Q	All mutations	Q	1.0	1
737	R	I	All mutations	I	2.9660590823381523	>1
737	R	E	All mutations	E	2.0	>1
737	R	G	All mutations	G	1.0	1
737	R	N	All mutations	N	3.0	>1
738	K	E	All mutations	E	1.0	1
738	K	V	All mutations	V	2.0	>1
738	K	M	All mutations	M	1.9993714644877436	>1
738	K	H	All mutations	H	2.0	>1
738	K	L	All mutations	L	2.0	>1
738	K	Y	All mutations	Y	2.0	>1
738	K	W	All mutations	W	2.9993714644877434	>1
738	K	A	All mutations	A	2.0	>1
738	K	F	All mutations	F	3.0	>1
738	K	G	All mutations	G	2.0	>1
738	K	P	All mutations	P	2.0	>1
738	K	I	All mutations	I	1.0006285355122564	1
738	K	Q	All mutations	Q	1.0	1
738	K	K	All mutations	K	0.0	0
738	K	S	All mutations	S	2.0	>1
738	K	D	All mutations	D	2.0	>1
738	K	R	All mutations	R	1.0	1
738	K	C	All mutations	C	3.0	>1
738	K	N	All mutations	N	1.0	1
738	K	T	All mutations	T	1.0	1
739	R	Y	All mutations	Y	2.9974858579509744	>1
739	R	R	All mutations	R	0.0	0
739	R	V	All mutations	V	2.0	>1
739	R	D	All mutations	D	2.9974858579509744	>1
739	R	T	All mutations	T	1.9987429289754872	>1
739	R	E	All mutations	E	2.0025141420490256	>1
739	R	S	All mutations	S	1.9962287869264614	>1
739	R	F	All mutations	F	2.9974858579509744	>1
739	R	C	All mutations	C	1.9974858579509742	>1
739	R	G	All mutations	G	1.0	1
739	R	H	All mutations	H	1.9987429289754872	>1
739	R	P	All mutations	P	1.0012570710245128	1
739	R	I	All mutations	I	2.9874292897548713	>1
739	R	N	All mutations	N	2.996228786926461	>1
739	R	K	All mutations	K	2.001257071024513	>1
739	R	M	All mutations	M	2.010056568196103	>1
739	R	Q	All mutations	Q	1.0037712130735386	1
739	R	W	All mutations	W	1.011313639220616	1
739	R	L	All mutations	L	1.0012570710245128	1
739	R	A	All mutations	A	2.0	>1
740	D	W	All mutations	W	2.9993714644877434	>1
740	D	T	All mutations	T	1.9974858579509742	>1
740	D	E	All mutations	E	1.0025141420490258	1
740	D	S	All mutations	S	1.9968573224387178	>1
740	D	F	All mutations	F	2.0006285355122566	>1
740	D	R	All mutations	R	1.9993714644877436	>1
740	D	L	All mutations	L	2.0	>1
740	D	Q	All mutations	Q	2.0	>1
740	D	H	All mutations	H	1.0012570710245128	1
740	D	P	All mutations	P	2.0	>1
740	D	I	All mutations	I	1.9974858579509742	>1
740	D	N	All mutations	N	0.9987429289754871	1
740	D	A	All mutations	A	1.0025141420490258	1
740	D	M	All mutations	M	2.9974858579509744	>1
740	D	K	All mutations	K	1.9974858579509742	>1
740	D	Y	All mutations	Y	1.0012570710245128	1
740	D	D	All mutations	D	0.003771213073538655	1
740	D	V	All mutations	V	1.0025141420490258	1
740	D	G	All mutations	G	1.0018856065367694	1
740	D	C	All mutations	C	2.0	>1
741	S	V	All mutations	V	2.0	>1
741	S	S	All mutations	S	0.0	0
741	S	F	All mutations	F	1.0119421747328725	1
741	S	R	All mutations	R	2.0	>1
741	S	W	All mutations	W	1.9905719673161533	>1
741	S	G	All mutations	G	2.0	>1
741	S	H	All mutations	H	2.0119421747328725	>1
741	S	P	All mutations	P	1.0	1
741	S	C	All mutations	C	1.0119421747328725	1
741	S	N	All mutations	N	2.0119421747328725	>1
741	S	A	All mutations	A	1.0	1
741	S	I	All mutations	I	2.0094280326838465	>1
741	S	M	All mutations	M	2.9905719673161535	>1
741	S	Y	All mutations	Y	1.0119421747328725	1
741	S	K	All mutations	K	2.9880578252671275	>1
741	S	L	All mutations	L	1.9880578252671275	>1
741	S	E	All mutations	E	2.9880578252671275	>1
741	S	T	All mutations	T	1.0	1
741	S	Q	All mutations	Q	2.9880578252671275	>1
741	S	D	All mutations	D	2.0119421747328725	>1
742	S	T	All mutations	T	1.0	1
742	S	Y	All mutations	Y	2.0	>1
742	S	R	All mutations	R	1.0	1
742	S	M	All mutations	M	2.0	>1
742	S	G	All mutations	G	1.0	1
742	S	W	All mutations	W	2.0	>1
742	S	Q	All mutations	Q	3.0	>1
742	S	S	All mutations	S	0.0	0
742	S	V	All mutations	V	2.0	>1
742	S	K	All mutations	K	2.0	>1
742	S	P	All mutations	P	2.0	>1
742	S	F	All mutations	F	2.0	>1
742	S	D	All mutations	D	2.0	>1
742	S	N	All mutations	N	1.0	1
742	S	C	All mutations	C	1.0	1
742	S	A	All mutations	A	2.0	>1
742	S	I	All mutations	I	1.0	1
742	S	H	All mutations	H	2.0	>1
742	S	L	All mutations	L	2.0	>1
742	S	E	All mutations	E	3.0	>1
743	I	F	All mutations	F	2.0	>1
743	I	R	All mutations	R	1.0	1
743	I	M	All mutations	M	1.0	1
743	I	I	All mutations	I	0.0	0
743	I	H	All mutations	H	3.0	>1
743	I	A	All mutations	A	2.0	>1
743	I	G	All mutations	G	2.0	>1
743	I	W	All mutations	W	3.0	>1
743	I	T	All mutations	T	1.0	1
743	I	D	All mutations	D	3.0	>1
743	I	P	All mutations	P	2.0	>1
743	I	Q	All mutations	Q	2.0	>1
743	I	C	All mutations	C	3.0	>1
743	I	N	All mutations	N	2.0	>1
743	I	K	All mutations	K	1.0	1
743	I	S	All mutations	S	2.0	>1
743	I	L	All mutations	L	1.0	1
743	I	V	All mutations	V	1.0	1
743	I	E	All mutations	E	2.0	>1
743	I	Y	All mutations	Y	3.0	>1
744	L	V	All mutations	V	1.0	1
744	L	I	All mutations	I	1.0	1
744	L	L	All mutations	L	0.0	0
744	L	Y	All mutations	Y	2.0	>1
744	L	E	All mutations	E	3.0	>1
744	L	P	All mutations	P	1.0	1
744	L	A	All mutations	A	2.0	>1
744	L	W	All mutations	W	3.0	>1
744	L	S	All mutations	S	2.0	>1
744	L	C	All mutations	C	2.0	>1
744	L	T	All mutations	T	2.0	>1
744	L	Q	All mutations	Q	2.0	>1
744	L	H	All mutations	H	1.0	1
744	L	D	All mutations	D	2.0	>1
744	L	G	All mutations	G	2.0	>1
744	L	R	All mutations	R	1.0	1
744	L	K	All mutations	K	3.0	>1
744	L	N	All mutations	N	2.0	>1
744	L	F	All mutations	F	1.0	1
744	L	M	All mutations	M	2.0	>1
745	T	M	All mutations	M	2.0	>1
745	T	L	All mutations	L	2.0	>1
745	T	R	All mutations	R	2.0	>1
745	T	H	All mutations	H	2.0	>1
745	T	P	All mutations	P	1.0	1
745	T	S	All mutations	S	1.0	1
745	T	T	All mutations	T	0.0	0
745	T	G	All mutations	G	2.0	>1
745	T	Y	All mutations	Y	2.0	>1
745	T	I	All mutations	I	1.0	1
745	T	W	All mutations	W	3.0	>1
745	T	A	All mutations	A	1.0	1
745	T	E	All mutations	E	3.0	>1
745	T	C	All mutations	C	2.0	>1
745	T	V	All mutations	V	2.0	>1
745	T	Q	All mutations	Q	3.0	>1
745	T	K	All mutations	K	2.0	>1
745	T	N	All mutations	N	1.0	1
745	T	F	All mutations	F	2.0	>1
745	T	D	All mutations	D	2.0	>1
746	D	D	All mutations	D	0.0	0
746	D	R	All mutations	R	2.0	>1
746	D	W	All mutations	W	3.0	>1
746	D	N	All mutations	N	1.0	1
746	D	H	All mutations	H	1.0	1
746	D	K	All mutations	K	2.0	>1
746	D	A	All mutations	A	1.0	1
746	D	V	All mutations	V	1.0	1
746	D	M	All mutations	M	3.0	>1
746	D	Q	All mutations	Q	2.0	>1
746	D	T	All mutations	T	2.0	>1
746	D	E	All mutations	E	1.0	1
746	D	F	All mutations	F	2.0	>1
746	D	Y	All mutations	Y	1.0	1
746	D	S	All mutations	S	2.0	>1
746	D	L	All mutations	L	2.0	>1
746	D	I	All mutations	I	2.0	>1
746	D	C	All mutations	C	2.0	>1
746	D	G	All mutations	G	1.0	1
746	D	P	All mutations	P	2.0	>1
747	S	I	All mutations	I	1.0	1
747	S	K	All mutations	K	2.0	>1
747	S	C	All mutations	C	1.0	1
747	S	M	All mutations	M	2.0	>1
747	S	L	All mutations	L	2.0	>1
747	S	R	All mutations	R	1.0	1
747	S	D	All mutations	D	2.0	>1
747	S	T	All mutations	T	1.0	1
747	S	W	All mutations	W	2.0	>1
747	S	F	All mutations	F	2.0	>1
747	S	S	All mutations	S	0.0	0
747	S	H	All mutations	H	2.0	>1
747	S	Y	All mutations	Y	2.0	>1
747	S	P	All mutations	P	2.0	>1
747	S	V	All mutations	V	2.0	>1
747	S	N	All mutations	N	1.0	1
747	S	A	All mutations	A	2.0	>1
747	S	G	All mutations	G	1.0	1
747	S	E	All mutations	E	3.0	>1
747	S	Q	All mutations	Q	3.0	>1
748	Q	V	All mutations	V	2.0	>1
748	Q	K	All mutations	K	1.0006285355122564	1
748	Q	W	All mutations	W	1.9993714644877436	>1
748	Q	L	All mutations	L	1.0	1
748	Q	S	All mutations	S	2.0	>1
748	Q	D	All mutations	D	2.0006285355122566	>1
748	Q	E	All mutations	E	1.0006285355122564	1
748	Q	R	All mutations	R	0.9993714644877436	1
748	Q	N	All mutations	N	2.0006285355122566	>1
748	Q	T	All mutations	T	2.0	>1
748	Q	F	All mutations	F	3.0	>1
748	Q	Q	All mutations	Q	0.0006285355122564425	1
748	Q	M	All mutations	M	2.0	>1
748	Q	I	All mutations	I	3.0	>1
748	Q	A	All mutations	A	2.0	>1
748	Q	G	All mutations	G	1.9993714644877436	>1
748	Q	P	All mutations	P	1.0	1
748	Q	H	All mutations	H	1.0006285355122564	1
748	Q	C	All mutations	C	2.9993714644877434	>1
748	Q	Y	All mutations	Y	2.0006285355122566	>1
749	T	A	All mutations	A	0.9993714644877436	1
749	T	H	All mutations	H	2.998742928975487	>1
749	T	C	All mutations	C	2.998742928975487	>1
749	T	D	All mutations	D	2.9981143934632306	>1
749	T	K	All mutations	K	1.0018856065367694	1
749	T	E	All mutations	E	2.0006285355122566	>1
749	T	F	All mutations	F	2.998742928975487	>1
749	T	I	All mutations	I	1.0006285355122564	1
749	T	G	All mutations	G	1.9993714644877436	>1
749	T	L	All mutations	L	2.0	>1
749	T	W	All mutations	W	3.0	>1
749	T	M	All mutations	M	2.0006285355122566	>1
749	T	R	All mutations	R	1.0018856065367694	1
749	T	T	All mutations	T	0.0006285355122564425	1
749	T	V	All mutations	V	1.9993714644877436	>1
749	T	N	All mutations	N	1.9993714644877436	>1
749	T	Y	All mutations	Y	2.998742928975487	>1
749	T	S	All mutations	S	1.0	1
749	T	P	All mutations	P	1.0	1
749	T	Q	All mutations	Q	2.001257071024513	>1
750	A	H	All mutations	H	3.0	>1
750	A	T	All mutations	T	1.0	1
750	A	C	All mutations	C	3.0	>1
750	A	A	All mutations	A	0.0	0
750	A	E	All mutations	E	1.0	1
750	A	P	All mutations	P	1.0	1
750	A	M	All mutations	M	2.0	>1
750	A	W	All mutations	W	2.0	>1
750	A	I	All mutations	I	3.0	>1
750	A	G	All mutations	G	1.0	1
750	A	R	All mutations	R	2.0	>1
750	A	Q	All mutations	Q	2.0	>1
750	A	N	All mutations	N	3.0	>1
750	A	D	All mutations	D	2.0	>1
750	A	S	All mutations	S	1.0	1
750	A	Y	All mutations	Y	3.0	>1
750	A	V	All mutations	V	1.0	1
750	A	K	All mutations	K	2.0	>1
750	A	F	All mutations	F	3.0	>1
750	A	L	All mutations	L	2.0	>1
751	T	V	All mutations	V	2.0	>1
751	T	N	All mutations	N	1.0	1
751	T	Q	All mutations	Q	3.0	>1
751	T	K	All mutations	K	2.0	>1
751	T	C	All mutations	C	2.0	>1
751	T	A	All mutations	A	1.0	1
751	T	P	All mutations	P	1.0	1
751	T	W	All mutations	W	3.0	>1
751	T	T	All mutations	T	0.0	0
751	T	D	All mutations	D	2.0	>1
751	T	G	All mutations	G	2.0	>1
751	T	F	All mutations	F	2.0	>1
751	T	L	All mutations	L	2.0	>1
751	T	H	All mutations	H	2.0	>1
751	T	Y	All mutations	Y	2.0	>1
751	T	I	All mutations	I	1.0	1
751	T	R	All mutations	R	2.0	>1
751	T	S	All mutations	S	1.0	1
751	T	M	All mutations	M	2.0	>1
751	T	E	All mutations	E	3.0	>1
752	K	A	All mutations	A	2.0	>1
752	K	P	All mutations	P	2.0	>1
752	K	D	All mutations	D	2.0	>1
752	K	I	All mutations	I	1.0	1
752	K	G	All mutations	G	2.0	>1
752	K	T	All mutations	T	1.0	1
752	K	V	All mutations	V	2.0	>1
752	K	Y	All mutations	Y	2.0	>1
752	K	M	All mutations	M	2.0	>1
752	K	R	All mutations	R	1.0	1
752	K	C	All mutations	C	3.0	>1
752	K	S	All mutations	S	2.0	>1
752	K	K	All mutations	K	0.0	0
752	K	N	All mutations	N	1.0	1
752	K	F	All mutations	F	3.0	>1
752	K	L	All mutations	L	2.0	>1
752	K	H	All mutations	H	2.0	>1
752	K	Q	All mutations	Q	1.0	1
752	K	E	All mutations	E	1.0	1
752	K	W	All mutations	W	3.0	>1
753	R	A	All mutations	A	2.0	>1
753	R	T	All mutations	T	1.0006285355122564	1
753	R	F	All mutations	F	2.998742928975487	>1
753	R	Q	All mutations	Q	2.0006285355122566	>1
753	R	Y	All mutations	Y	2.998742928975487	>1
753	R	H	All mutations	H	2.9993714644877434	>1
753	R	M	All mutations	M	1.7762413576367064	>1
753	R	P	All mutations	P	2.0	>1
753	R	G	All mutations	G	1.0	1
753	R	C	All mutations	C	1.9987429289754872	>1
753	R	D	All mutations	D	2.9993714644877434	>1
753	R	N	All mutations	N	2.0	>1
753	R	E	All mutations	E	2.0006285355122566	>1
753	R	W	All mutations	W	1.7749842866121937	>1
753	R	R	All mutations	R	0.0006285355122564425	1
753	R	I	All mutations	I	1.2250157133878063	>1
753	R	V	All mutations	V	2.0	>1
753	R	S	All mutations	S	1.0	1
753	R	K	All mutations	K	1.0012570710245128	1
753	R	L	All mutations	L	2.0	>1
754	I	D	All mutations	D	1.9993714644877436	>1
754	I	Y	All mutations	Y	2.0	>1
754	I	R	All mutations	R	1.9987429289754872	>1
754	I	E	All mutations	E	2.9993714644877434	>1
754	I	S	All mutations	S	1.0018856065367694	1
754	I	T	All mutations	T	1.0018856065367694	1
754	I	Q	All mutations	Q	2.998742928975487	>1
754	I	G	All mutations	G	1.9993714644877436	>1
754	I	A	All mutations	A	1.9993714644877436	>1
754	I	W	All mutations	W	3.0	>1
754	I	V	All mutations	V	0.9993714644877436	1
754	I	H	All mutations	H	1.9987429289754872	>1
754	I	N	All mutations	N	1.0018856065367694	1
754	I	M	All mutations	M	1.0018856065367694	1
754	I	C	All mutations	C	2.0	>1
754	I	L	All mutations	L	0.9987429289754871	1
754	I	P	All mutations	P	1.9987429289754872	>1
754	I	K	All mutations	K	2.0018856065367694	>1
754	I	F	All mutations	F	1.0	1
754	I	I	All mutations	I	0.0018856065367693275	1
755	R	L	All mutations	L	1.0006285355122564	1
755	R	S	All mutations	S	1.9208045254556882	>1
755	R	D	All mutations	D	2.9195474544311755	>1
755	R	V	All mutations	V	1.9993714644877436	>1
755	R	K	All mutations	K	2.078566939032055	>1
755	R	A	All mutations	A	1.9993714644877436	>1
755	R	W	All mutations	W	1.1162790697674418	>1
755	R	I	All mutations	I	2.8843494657448145	>1
755	R	Y	All mutations	Y	2.9201759899434316	>1
755	R	Q	All mutations	Q	1.0791954745443118	1
755	R	T	All mutations	T	2.0	>1
755	R	H	All mutations	H	1.9208045254556882	>1
755	R	E	All mutations	E	2.077938403519799	>1
755	R	N	All mutations	N	2.9201759899434316	>1
755	R	G	All mutations	G	1.0	1
755	R	P	All mutations	P	1.0006285355122564	1
755	R	C	All mutations	C	1.9214330609679446	>1
755	R	F	All mutations	F	2.9208045254556882	>1
755	R	M	All mutations	M	2.1156505342551855	>1
755	R	R	All mutations	R	0.001257071024512885	1
756	M	T	All mutations	T	0.9987429289754871	1
756	M	S	All mutations	S	1.9974858579509742	>1
756	M	C	All mutations	C	2.998742928975487	>1
756	M	Y	All mutations	Y	2.9993714644877434	>1
756	M	V	All mutations	V	1.0018856065367694	1
756	M	A	All mutations	A	1.9987429289754872	>1
756	M	F	All mutations	F	2.001257071024513	>1
756	M	N	All mutations	N	1.9993714644877436	>1
756	M	D	All mutations	D	2.9993714644877434	>1
756	M	R	All mutations	R	1.0	1
756	M	E	All mutations	E	2.0006285355122566	>1
756	M	K	All mutations	K	1.0006285355122564	1
756	M	L	All mutations	L	1.0018856065367694	1
756	M	M	All mutations	M	0.00251414204902577	1
756	M	G	All mutations	G	1.9993714644877436	>1
756	M	Q	All mutations	Q	2.0006285355122566	>1
756	M	H	All mutations	H	2.9993714644877434	>1
756	M	W	All mutations	W	2.0	>1
756	M	P	All mutations	P	1.9987429289754872	>1
756	M	I	All mutations	I	1.0012570710245128	1
757	A	D	All mutations	D	1.0	1
757	A	W	All mutations	W	3.0	>1
757	A	L	All mutations	L	1.9082338152105593	>1
757	A	Y	All mutations	Y	2.0	>1
757	A	K	All mutations	K	3.0	>1
757	A	I	All mutations	I	1.9082338152105593	>1
757	A	M	All mutations	M	2.9082338152105596	>1
757	A	N	All mutations	N	2.0	>1
757	A	H	All mutations	H	2.0	>1
757	A	G	All mutations	G	1.0	1
757	A	P	All mutations	P	1.0917661847894407	1
757	A	C	All mutations	C	2.0	>1
757	A	A	All mutations	A	0.0917661847894406	1
757	A	Q	All mutations	Q	3.0	>1
757	A	V	All mutations	V	0.9082338152105593	1
757	A	E	All mutations	E	2.0	>1
757	A	R	All mutations	R	2.0	>1
757	A	S	All mutations	S	1.0917661847894407	1
757	A	T	All mutations	T	1.0917661847894407	1
757	A	F	All mutations	F	1.9082338152105593	>1
758	I	V	All mutations	V	1.0018856065367694	1
758	I	K	All mutations	K	1.9993714644877436	>1
758	I	T	All mutations	T	0.9987429289754871	1
758	I	L	All mutations	L	1.0012570710245128	1
758	I	Y	All mutations	Y	2.001257071024513	>1
758	I	I	All mutations	I	0.0031426775612822125	1
758	I	M	All mutations	M	1.0018856065367694	1
758	I	H	All mutations	H	2.0006285355122566	>1
758	I	N	All mutations	N	1.0018856065367694	1
758	I	G	All mutations	G	2.0	>1
758	I	P	All mutations	P	1.9974858579509742	>1
758	I	F	All mutations	F	1.0031426775612822	1
758	I	Q	All mutations	Q	2.9981143934632306	>1
758	I	E	All mutations	E	2.998742928975487	>1
758	I	R	All mutations	R	1.9987429289754872	>1
758	I	D	All mutations	D	2.001257071024513	>1
758	I	S	All mutations	S	1.0012570710245128	1
758	I	C	All mutations	C	2.001257071024513	>1
758	I	A	All mutations	A	1.9981143934632306	>1
758	I	W	All mutations	W	2.9993714644877434	>1
759	N	L	All mutations	L	1.9993714644877436	>1
759	N	V	All mutations	V	2.0	>1
759	N	A	All mutations	A	2.0	>1
759	N	C	All mutations	C	2.0018856065367694	>1
759	N	D	All mutations	D	1.0018856065367694	1
759	N	E	All mutations	E	1.9981143934632306	>1
759	N	F	All mutations	F	2.0018856065367694	>1
759	N	G	All mutations	G	2.0	>1
759	N	H	All mutations	H	1.0012570710245128	1
759	N	W	All mutations	W	2.998742928975487	>1
759	N	I	All mutations	I	1.0018856065367694	1
759	N	M	All mutations	M	1.9993714644877436	>1
759	N	N	All mutations	N	0.00251414204902577	1
759	N	P	All mutations	P	1.9993714644877436	>1
759	N	Q	All mutations	Q	1.9974858579509742	>1
759	N	R	All mutations	R	1.9981143934632306	>1
759	N	S	All mutations	S	1.0018856065367694	1
759	N	T	All mutations	T	1.0006285355122564	1
759	N	K	All mutations	K	0.9987429289754871	1
759	N	Y	All mutations	Y	1.0018856065367694	1