##Databases: KEGG PATHWAY #fg 126 #bg 6644 ##Statistical test method: hypergeometric test ##FDR correction method: Benjamini and Hochberg #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink Amphetamine addiction KEGG PATHWAY hsa05031 6 70 0.00200818860703 0.337375685981 CREB5|CAMK2A|CAMK2B|GRIN2B|GRIN2C|MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa05031/hsa:9586%09red/hsa:816%09red/hsa:815%09red/hsa:2905%09red/hsa:2904%09red/hsa:4128%09red Insulin secretion KEGG PATHWAY hsa04911 6 87 0.00595857972585 0.363962935519 SNAP25|KCNJ11|CREB5|CAMK2A|CAMK2B|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04911/hsa:9586%09red/hsa:816%09red/hsa:815%09red/hsa:478%09red/hsa:3767%09red/hsa:6616%09red ABC transporters KEGG PATHWAY hsa02010 4 44 0.00932067819118 0.363962935519 ABCA10|ABCA12|ABCA5|ABCG4 http://www.genome.jp/kegg-bin/show_pathway?hsa02010/hsa:10349%09red/hsa:64137%09red/hsa:26154%09red/hsa:23461%09red MAPK signaling pathway KEGG PATHWAY hsa04010 11 260 0.0101070906598 0.363962935519 RASGRP1|HSPA6|IL1R1|CACNB2|PLA2G4C|MAP3K12|MAPK8IP2|PLA2G4E|RELB|MAPK8IP1|FGF1 http://www.genome.jp/kegg-bin/show_pathway?hsa04010/hsa:3554%09red/hsa:123745%09red/hsa:23542%09red/hsa:10125%09red/hsa:2246%09red/hsa:783%09red/hsa:3310%09red/hsa:5971%09red/hsa:8605%09red/hsa:7786%09red/hsa:9479%09red Cocaine addiction KEGG PATHWAY hsa05030 4 50 0.0144982651215 0.363962935519 GRIN2B|GRIN2C|CREB5|MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa05030/hsa:2905%09red/hsa:2904%09red/hsa:4128%09red/hsa:9586%09red Wnt signaling pathway KEGG PATHWAY hsa04310 7 141 0.0173533017343 0.363962935519 PRICKLE1|NKD2|CAMK2A|CAMK2B|WNT4|WNT5B|SOX17 http://www.genome.jp/kegg-bin/show_pathway?hsa04310/hsa:815%09red/hsa:816%09red/hsa:81029%09red/hsa:64321%09red/hsa:85409%09red/hsa:144165%09red/hsa:54361%09red TNF signaling pathway KEGG PATHWAY hsa04668 6 110 0.0177971958962 0.363962935519 TRAF1|CXCL2|CCL5|CREB5|MMP9|CCL20 http://www.genome.jp/kegg-bin/show_pathway?hsa04668/hsa:4318%09red/hsa:9586%09red/hsa:2920%09red/hsa:6364%09red/hsa:6352%09red/hsa:7185%09red Cholinergic synapse KEGG PATHWAY hsa04725 6 113 0.0200591816195 0.363962935519 CREB5|CAMK2A|CAMK2B|CHRNA7|CHRM1|ACHE http://www.genome.jp/kegg-bin/show_pathway?hsa04725/hsa:9586%09red/hsa:816%09red/hsa:815%09red/hsa:1128%09red/hsa:1139%09red/hsa:43%09red Chemokine signaling pathway KEGG PATHWAY hsa04062 8 189 0.0267830090148 0.363962935519 CXCL2|ITK|SHC2|CCL5|VAV1|CXCL11|CCL20|CCL26 http://www.genome.jp/kegg-bin/show_pathway?hsa04062/hsa:10344%09red/hsa:2920%09red/hsa:6373%09red/hsa:3702%09red/hsa:25759%09red/hsa:6352%09red/hsa:7409%09red/hsa:6364%09red Hippo signaling pathway KEGG PATHWAY hsa04390 7 156 0.0283711912194 0.363962935519 ID2|ID3|PARD6A|WNT4|WNT5B|WTIP|FGF1 http://www.genome.jp/kegg-bin/show_pathway?hsa04390/hsa:81029%09red/hsa:2246%09red/hsa:126374%09red/hsa:3399%09red/hsa:3398%09red/hsa:50855%09red/hsa:54361%09red NF-kappa B signaling pathway KEGG PATHWAY hsa04064 5 92 0.0300619679025 0.363962935519 RELB|DDX58|CXCL2|IL1R1|TRAF1 http://www.genome.jp/kegg-bin/show_pathway?hsa04064/hsa:2920%09red/hsa:23586%09red/hsa:5971%09red/hsa:3554%09red/hsa:7185%09red GnRH signaling pathway KEGG PATHWAY hsa04912 5 92 0.0300619679025 0.363962935519 CGA|PLA2G4C|CAMK2B|CAMK2A|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04912/hsa:816%09red/hsa:8605%09red/hsa:815%09red/hsa:1081%09red/hsa:123745%09red VEGF signaling pathway KEGG PATHWAY hsa04370 4 63 0.0311078574241 0.363962935519 PLA2G4C|SPHK1|SHC2|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04370/hsa:8605%09red/hsa:25759%09red/hsa:8877%09red/hsa:123745%09red Dopaminergic synapse KEGG PATHWAY hsa04728 6 131 0.0377935674263 0.363962935519 KIF5A|CREB5|CAMK2A|CAMK2B|GRIN2B|MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa04728/hsa:9586%09red/hsa:816%09red/hsa:815%09red/hsa:2904%09red/hsa:3798%09red/hsa:4128%09red Nicotine addiction KEGG PATHWAY hsa05033 3 40 0.0395449984039 0.363962935519 GRIN2B|GRIN2C|CHRNA7 http://www.genome.jp/kegg-bin/show_pathway?hsa05033/hsa:2905%09red/hsa:2904%09red/hsa:1139%09red Arachidonic acid metabolism KEGG PATHWAY hsa00590 4 68 0.0395976755823 0.363962935519 PLA2G4C|CYP4F2|CYP4F3|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa00590/hsa:4051%09red/hsa:8529%09red/hsa:123745%09red/hsa:8605%09red Estrogen signaling pathway KEGG PATHWAY hsa04915 5 100 0.0408979112881 0.363962935519 CREB5|ESR1|HSPA6|SHC2|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa04915/hsa:4318%09red/hsa:25759%09red/hsa:9586%09red/hsa:2099%09red/hsa:3310%09red Long-term potentiation KEGG PATHWAY hsa04720 4 69 0.0414393054868 0.363962935519 GRIN2B|GRIN2C|CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04720/hsa:2905%09red/hsa:2904%09red/hsa:815%09red/hsa:816%09red Measles KEGG PATHWAY hsa05162 6 134 0.041489531121 0.363962935519 IFIH1|HSPA6|SH2D1A|DDX58|MX1|OAS2 http://www.genome.jp/kegg-bin/show_pathway?hsa05162/hsa:64135%09red/hsa:4599%09red/hsa:3310%09red/hsa:4939%09red/hsa:4068%09red/hsa:23586%09red Fc epsilon RI signaling pathway KEGG PATHWAY hsa04664 4 70 0.0433289208951 0.363962935519 VAV1|PLA2G4C|INPP5D|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04664/hsa:8605%09red/hsa:7409%09red/hsa:123745%09red/hsa:3635%09red Prolactin signaling pathway KEGG PATHWAY hsa04917 4 72 0.047252027899 0.366271977987 CGA|SOCS2|SHC2|ESR1 http://www.genome.jp/kegg-bin/show_pathway?hsa04917/hsa:8835%09red/hsa:25759%09red/hsa:1081%09red/hsa:2099%09red Influenza A KEGG PATHWAY hsa05164 7 176 0.0493665175882 0.366271977987 IFIH1|HSPA6|CCL5|DDX58|MX1|OAS2|RSAD2 http://www.genome.jp/kegg-bin/show_pathway?hsa05164/hsa:64135%09red/hsa:4599%09red/hsa:23586%09red/hsa:3310%09red/hsa:4939%09red/hsa:6352%09red/hsa:91543%09red Gastric acid secretion KEGG PATHWAY hsa04971 4 75 0.0534953911589 0.366271977987 ATP1A3|MYLK2|CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04971/hsa:816%09red/hsa:85366%09red/hsa:478%09red/hsa:815%09red Alcoholism KEGG PATHWAY hsa05034 7 180 0.0545047586291 0.366271977987 SHC2|CREB5|GRIN2B|GRIN2C|MAOA|HIST2H4A|HIST1H2AB http://www.genome.jp/kegg-bin/show_pathway?hsa05034/hsa:9586%09red/hsa:25759%09red/hsa:4128%09red/hsa:8370%09red/hsa:2905%09red/hsa:2904%09red/hsa:8335%09red Tuberculosis KEGG PATHWAY hsa05152 7 180 0.0545047586291 0.366271977987 CD74|SPHK1|IL23A|CAMK2A|CAMK2B|CORO1A|ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa05152/hsa:51561%09red/hsa:11151%09red/hsa:816%09red/hsa:815%09red/hsa:3684%09red/hsa:972%09red/hsa:8877%09red Calcium signaling pathway KEGG PATHWAY hsa04020 7 183 0.0585713510093 0.378461037291 SPHK1|MYLK2|CAMK2A|CHRM1|GRIN2C|CHRNA7|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04020/hsa:85366%09red/hsa:816%09red/hsa:815%09red/hsa:1128%09red/hsa:8877%09red/hsa:2905%09red/hsa:1139%09red Herpes simplex infection KEGG PATHWAY hsa05168 7 185 0.0613845353978 0.381948220253 CD74|TRAF1|IFIH1|CCL5|HLA-F|OAS2|DDX58 http://www.genome.jp/kegg-bin/show_pathway?hsa05168/hsa:972%09red/hsa:64135%09red/hsa:4939%09red/hsa:6352%09red/hsa:23586%09red/hsa:7185%09red/hsa:3134%09red Ovarian steroidogenesis KEGG PATHWAY hsa04913 3 51 0.0718806408717 0.422901053712 CGA|PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04913/hsa:8605%09red/hsa:1081%09red/hsa:123745%09red Glutamatergic synapse KEGG PATHWAY hsa04724 5 118 0.0730007771289 0.422901053712 GRIN2B|GRIN2C|DLGAP1|PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04724/hsa:2905%09red/hsa:2904%09red/hsa:9229%09red/hsa:123745%09red/hsa:8605%09red Neuroactive ligand-receptor interaction KEGG PATHWAY hsa04080 9 275 0.0767631117271 0.423386704158 GRID1|CALCRL|CGA|CHRM1|GRIN2B|GRIN2C|CHRNA7|LPAR2|CHRNA9 http://www.genome.jp/kegg-bin/show_pathway?hsa04080/hsa:1081%09red/hsa:55584%09red/hsa:2894%09red/hsa:1128%09red/hsa:1139%09red/hsa:2904%09red/hsa:10203%09red/hsa:2905%09red/hsa:9170%09red Vascular smooth muscle contraction KEGG PATHWAY hsa04270 5 121 0.0793942611059 0.423386704158 ACTA2|PLA2G4C|MYLK2|PLA2G4E|CALCRL http://www.genome.jp/kegg-bin/show_pathway?hsa04270/hsa:8605%09red/hsa:85366%09red/hsa:123745%09red/hsa:59%09red/hsa:10203%09red alpha-Linolenic acid metabolism KEGG PATHWAY hsa00592 2 25 0.0806450865063 0.423386704158 PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa00592/hsa:8605%09red/hsa:123745%09red Legionellosis KEGG PATHWAY hsa05134 3 55 0.0858424898149 0.43326537429 CXCL2|HSPA6|ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa05134/hsa:2920%09red/hsa:3684%09red/hsa:3310%09red Epstein-Barr virus infection KEGG PATHWAY hsa05169 7 202 0.0886206772421 0.43326537429 TRAF1|DDX58|HSPA6|ENTPD1|HLA-F|RELB|POLR2J2 http://www.genome.jp/kegg-bin/show_pathway?hsa05169/hsa:953%09red/hsa:3310%09red/hsa:5971%09red/hsa:23586%09red/hsa:7185%09red/hsa:246721%09red/hsa:3134%09red Rheumatoid arthritis KEGG PATHWAY hsa05323 4 90 0.0909973314091 0.43326537429 CCL20|MMP1|IL23A|CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa05323/hsa:4312%09red/hsa:6364%09red/hsa:51561%09red/hsa:6352%09red Fc gamma R-mediated phagocytosis KEGG PATHWAY hsa04666 4 91 0.0938545980152 0.43326537429 VAV1|SPHK1|INPP5D|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04666/hsa:8877%09red/hsa:7409%09red/hsa:123745%09red/hsa:3635%09red Focal adhesion KEGG PATHWAY hsa04510 7 207 0.0977602945678 0.43326537429 PGF|SHC2|VAV1|MYLK2|ITGA7|COL27A1|LAMB4 http://www.genome.jp/kegg-bin/show_pathway?hsa04510/hsa:5228%09red/hsa:85366%09red/hsa:25759%09red/hsa:3679%09red/hsa:85301%09red/hsa:22798%09red/hsa:7409%09red Histidine metabolism KEGG PATHWAY hsa00340 2 28 0.0980005013274 0.43326537429 MAOA|CARNS1 http://www.genome.jp/kegg-bin/show_pathway?hsa00340/hsa:4128%09red/hsa:57571%09red Circadian entrainment KEGG PATHWAY hsa04713 4 97 0.111871651263 0.476407433185 GRIN2B|GRIN2C|CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04713/hsa:2905%09red/hsa:2904%09red/hsa:815%09red/hsa:816%09red Regulation of actin cytoskeleton KEGG PATHWAY hsa04810 7 215 0.113430341234 0.476407433185 VAV1|MYLK2|CHRM1|ITGA7|INSRR|FGF1|ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa04810/hsa:85366%09red/hsa:2246%09red/hsa:3679%09red/hsa:3684%09red/hsa:1128%09red/hsa:7409%09red/hsa:3645%09red Melanogenesis KEGG PATHWAY hsa04916 4 101 0.124677308086 0.494360611895 WNT5B|CAMK2A|CAMK2B|WNT4 http://www.genome.jp/kegg-bin/show_pathway?hsa04916/hsa:816%09red/hsa:81029%09red/hsa:815%09red/hsa:54361%09red Glioma KEGG PATHWAY hsa05214 3 65 0.125175541765 0.494360611895 CAMK2B|CAMK2A|SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa05214/hsa:25759%09red/hsa:816%09red/hsa:815%09red Linoleic acid metabolism KEGG PATHWAY hsa00591 2 33 0.128926701217 0.494360611895 PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa00591/hsa:8605%09red/hsa:123745%09red Cytokine-cytokine receptor interaction KEGG PATHWAY hsa04060 8 266 0.131753575315 0.494360611895 CXCL2|IL23A|CCL5|IL24|CXCL11|CCL20|IL1R1|CCL26 http://www.genome.jp/kegg-bin/show_pathway?hsa04060/hsa:51561%09red/hsa:3554%09red/hsa:2920%09red/hsa:6373%09red/hsa:11009%09red/hsa:6352%09red/hsa:6364%09red/hsa:10344%09red Proteoglycans in cancer KEGG PATHWAY hsa05205 7 225 0.134774889261 0.494360611895 ESR1|CAMK2A|CAMK2B|WNT4|MMP9|WNT5B|FGF1 http://www.genome.jp/kegg-bin/show_pathway?hsa05205/hsa:4318%09red/hsa:815%09red/hsa:816%09red/hsa:81029%09red/hsa:2246%09red/hsa:2099%09red/hsa:54361%09red African trypanosomiasis KEGG PATHWAY hsa05143 2 34 0.135360643733 0.494360611895 IDO1|APOL1 http://www.genome.jp/kegg-bin/show_pathway?hsa05143/hsa:8542%09red/hsa:3620%09red Hepatitis B KEGG PATHWAY hsa05161 5 147 0.14646564684 0.503669283396 DDX58|EGR3|IFIH1|CREB5|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa05161/hsa:64135%09red/hsa:4318%09red/hsa:1960%09red/hsa:9586%09red/hsa:23586%09red SNARE interactions in vesicular transport KEGG PATHWAY hsa04130 2 36 0.148435435828 0.503669283396 SNAP25|STX3 http://www.genome.jp/kegg-bin/show_pathway?hsa04130/hsa:6809%09red/hsa:6616%09red RIG-I-like receptor signaling pathway KEGG PATHWAY hsa04622 3 71 0.151370735027 0.503669283396 IFIH1|ISG15|DDX58 http://www.genome.jp/kegg-bin/show_pathway?hsa04622/hsa:64135%09red/hsa:9636%09red/hsa:23586%09red Amoebiasis KEGG PATHWAY hsa05146 4 109 0.152032121672 0.503669283396 COL27A1|ITGAM|IL1R1|LAMB4 http://www.genome.jp/kegg-bin/show_pathway?hsa05146/hsa:22798%09red/hsa:3554%09red/hsa:85301%09red/hsa:3684%09red Bile secretion KEGG PATHWAY hsa04976 3 72 0.155897635337 0.503669283396 NR1H4|SLC51B|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04976/hsa:9971%09red/hsa:478%09red/hsa:123264%09red Thyroid hormone synthesis KEGG PATHWAY hsa04918 3 72 0.155897635337 0.503669283396 CGA|CREB5|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04918/hsa:478%09red/hsa:1081%09red/hsa:9586%09red Bladder cancer KEGG PATHWAY hsa05219 2 38 0.161754010988 0.505479788699 MMP1|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa05219/hsa:4312%09red/hsa:4318%09red Pathways in cancer KEGG PATHWAY hsa05200 9 327 0.167221373488 0.505479788699 PGF|TRAF1|EGLN2|WNT4|MMP9|WNT5B|LAMB4|FGF1|MMP1 http://www.genome.jp/kegg-bin/show_pathway?hsa05200/hsa:5228%09red/hsa:4318%09red/hsa:4312%09red/hsa:112398%09red/hsa:81029%09red/hsa:2246%09red/hsa:22798%09red/hsa:54361%09red/hsa:7185%09red Tyrosine metabolism KEGG PATHWAY hsa00350 2 39 0.1684932629 0.505479788699 HGD|MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa00350/hsa:4128%09red/hsa:3081%09red Aldosterone-regulated sodium reabsorption KEGG PATHWAY hsa04960 2 39 0.1684932629 0.505479788699 FXYD4|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04960/hsa:53828%09red/hsa:478%09red Tryptophan metabolism KEGG PATHWAY hsa00380 2 40 0.175280013663 0.516614777111 MAOA|IDO1 http://www.genome.jp/kegg-bin/show_pathway?hsa00380/hsa:3620%09red/hsa:4128%09red Antigen processing and presentation KEGG PATHWAY hsa04612 3 78 0.183895467792 0.527497900529 CD74|HSPA6|HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa04612/hsa:3134%09red/hsa:972%09red/hsa:3310%09red Leukocyte transendothelial migration KEGG PATHWAY hsa04670 4 118 0.185252238876 0.527497900529 VAV1|ITK|ITGAM|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa04670/hsa:4318%09red/hsa:3684%09red/hsa:7409%09red/hsa:3702%09red Ether lipid metabolism KEGG PATHWAY hsa00565 2 42 0.188979436831 0.529142423127 PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa00565/hsa:8605%09red/hsa:123745%09red TGF-beta signaling pathway KEGG PATHWAY hsa04350 3 80 0.193512936266 0.532953660535 CHRD|ID2|ID3 http://www.genome.jp/kegg-bin/show_pathway?hsa04350/hsa:8646%09red/hsa:3399%09red/hsa:3398%09red Riboflavin metabolism KEGG PATHWAY hsa00740 1 13 0.220523844522 0.593383133256 ACPP http://www.genome.jp/kegg-bin/show_pathway?hsa00740/hsa:55%09red ECM-receptor interaction KEGG PATHWAY hsa04512 3 87 0.228079472616 0.593383133256 COL27A1|LAMB4|ITGA7 http://www.genome.jp/kegg-bin/show_pathway?hsa04512/hsa:22798%09red/hsa:3679%09red/hsa:85301%09red Endocrine and other factor-regulated calcium reabsorption KEGG PATHWAY hsa04961 2 48 0.230810847494 0.593383133256 ATP1A3|ESR1 http://www.genome.jp/kegg-bin/show_pathway?hsa04961/hsa:478%09red/hsa:2099%09red Type II diabetes mellitus KEGG PATHWAY hsa04930 2 48 0.230810847494 0.593383133256 KCNJ11|SOCS2 http://www.genome.jp/kegg-bin/show_pathway?hsa04930/hsa:8835%09red/hsa:3767%09red ErbB signaling pathway KEGG PATHWAY hsa04012 3 88 0.23311480235 0.593383133256 CAMK2B|CAMK2A|SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa04012/hsa:25759%09red/hsa:816%09red/hsa:815%09red Glycerophospholipid metabolism KEGG PATHWAY hsa00564 3 91 0.248338376703 0.605084973493 PLA2G4C|ACHE|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa00564/hsa:8605%09red/hsa:43%09red/hsa:123745%09red Mineral absorption KEGG PATHWAY hsa04978 2 51 0.251968960289 0.605084973493 TRPV6|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04978/hsa:55503%09red/hsa:478%09red Hedgehog signaling pathway KEGG PATHWAY hsa04340 2 51 0.251968960289 0.605084973493 WNT5B|WNT4 http://www.genome.jp/kegg-bin/show_pathway?hsa04340/hsa:81029%09red/hsa:54361%09red Transcriptional misregulation in cancer KEGG PATHWAY hsa05202 5 179 0.252118738955 0.605084973493 TRAF1|ID2|HMGA2|ITGAM|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa05202/hsa:4318%09red/hsa:3398%09red/hsa:8091%09red/hsa:3684%09red/hsa:7185%09red Amyotrophic lateral sclerosis (ALS) KEGG PATHWAY hsa05014 2 53 0.266108087688 0.620918871272 GRIN2B|GRIN2C http://www.genome.jp/kegg-bin/show_pathway?hsa05014/hsa:2905%09red/hsa:2904%09red Autoimmune thyroid disease KEGG PATHWAY hsa05320 2 53 0.266108087688 0.620918871272 CGA|HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa05320/hsa:1081%09red/hsa:3134%09red Basal cell carcinoma KEGG PATHWAY hsa05217 2 55 0.280248880397 0.64226488719 WNT5B|WNT4 http://www.genome.jp/kegg-bin/show_pathway?hsa05217/hsa:81029%09red/hsa:54361%09red Phenylalanine metabolism KEGG PATHWAY hsa00360 1 18 0.291839812093 0.64226488719 MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa00360/hsa:4128%09red Steroid biosynthesis KEGG PATHWAY hsa00100 1 18 0.291839812093 0.64226488719 CYP24A1 http://www.genome.jp/kegg-bin/show_pathway?hsa00100/hsa:1591%09red Arginine and proline metabolism KEGG PATHWAY hsa00330 2 57 0.294371406629 0.64226488719 MAOA|CARNS1 http://www.genome.jp/kegg-bin/show_pathway?hsa00330/hsa:4128%09red/hsa:57571%09red NOD-like receptor signaling pathway KEGG PATHWAY hsa04621 2 57 0.294371406629 0.64226488719 CXCL2|CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa04621/hsa:6352%09red/hsa:2920%09red Long-term depression KEGG PATHWAY hsa04730 2 60 0.315480949126 0.664986836169 PLA2G4C|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04730/hsa:8605%09red/hsa:123745%09red Inositol phosphate metabolism KEGG PATHWAY hsa00562 2 61 0.32248921372 0.664986836169 INPP5J|INPP5D http://www.genome.jp/kegg-bin/show_pathway?hsa00562/hsa:27124%09red/hsa:3635%09red HIF-1 signaling pathway KEGG PATHWAY hsa04066 3 106 0.326087341682 0.664986836169 EGLN2|CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04066/hsa:816%09red/hsa:815%09red/hsa:112398%09red T cell receptor signaling pathway KEGG PATHWAY hsa04660 3 106 0.326087341682 0.664986836169 VAV1|RASGRP1|ITK http://www.genome.jp/kegg-bin/show_pathway?hsa04660/hsa:3702%09red/hsa:10125%09red/hsa:7409%09red Toll-like receptor signaling pathway KEGG PATHWAY hsa04620 3 107 0.331311374537 0.664986836169 CXCL11|IRF5|CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa04620/hsa:6373%09red/hsa:3663%09red/hsa:6352%09red PI3K-Akt signaling pathway KEGG PATHWAY hsa04151 8 346 0.333790803536 0.664986836169 PGF|CREB5|CHRM1|ITGA7|COL27A1|LPAR2|LAMB4|FGF1 http://www.genome.jp/kegg-bin/show_pathway?hsa04151/hsa:5228%09red/hsa:9586%09red/hsa:2246%09red/hsa:3679%09red/hsa:85301%09red/hsa:1128%09red/hsa:22798%09red/hsa:9170%09red Synaptic vesicle cycle KEGG PATHWAY hsa04721 2 63 0.336451673062 0.664986836169 SNAP25|STX3 http://www.genome.jp/kegg-bin/show_pathway?hsa04721/hsa:6809%09red/hsa:6616%09red Cytosolic DNA-sensing pathway KEGG PATHWAY hsa04623 2 63 0.336451673062 0.664986836169 DDX58|CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa04623/hsa:6352%09red/hsa:23586%09red Endocytosis KEGG PATHWAY hsa04144 5 203 0.341021502906 0.66618154056 HLA-F|MVB12B|HSPA6|PARD6A|SH3GL2 http://www.genome.jp/kegg-bin/show_pathway?hsa04144/hsa:50855%09red/hsa:89853%09red/hsa:3134%09red/hsa:6456%09red/hsa:3310%09red Viral carcinogenesis KEGG PATHWAY hsa05203 5 207 0.356185183133 0.680930675603 TRAF1|CREB5|HIST2H4A|HLA-F|EGR3 http://www.genome.jp/kegg-bin/show_pathway?hsa05203/hsa:7185%09red/hsa:8370%09red/hsa:1960%09red/hsa:9586%09red/hsa:3134%09red Proximal tubule bicarbonate reclamation KEGG PATHWAY hsa04964 1 23 0.356677972935 0.680930675603 ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04964/hsa:478%09red Serotonergic synapse KEGG PATHWAY hsa04726 3 114 0.367809889914 0.688651826592 PLA2G4C|MAOA|PLA2G4E http://www.genome.jp/kegg-bin/show_pathway?hsa04726/hsa:8605%09red/hsa:4128%09red/hsa:123745%09red Vitamin digestion and absorption KEGG PATHWAY hsa04977 1 24 0.368920621389 0.688651826592 TCN2 http://www.genome.jp/kegg-bin/show_pathway?hsa04977/hsa:6948%09red Complement and coagulation cascades KEGG PATHWAY hsa04610 2 69 0.377782430837 0.697444487698 TFPI|SERPINF2 http://www.genome.jp/kegg-bin/show_pathway?hsa04610/hsa:7035%09red/hsa:5345%09red HTLV-I infection KEGG PATHWAY hsa05166 6 264 0.385139110839 0.70329750675 HLA-F|WNT4|ZFP36|WNT5B|RELB|IL1R1 http://www.genome.jp/kegg-bin/show_pathway?hsa05166/hsa:7538%09red/hsa:3554%09red/hsa:81029%09red/hsa:5971%09red/hsa:54361%09red/hsa:3134%09red Glycosphingolipid biosynthesis - lacto and neolacto series KEGG PATHWAY hsa00601 1 26 0.392716745482 0.709423798289 FUT3 http://www.genome.jp/kegg-bin/show_pathway?hsa00601/hsa:2525%09red Neurotrophin signaling pathway KEGG PATHWAY hsa04722 3 120 0.398840636322 0.712821562788 CAMK2B|CAMK2A|SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa04722/hsa:25759%09red/hsa:816%09red/hsa:815%09red B cell receptor signaling pathway KEGG PATHWAY hsa04662 2 74 0.411410103803 0.72401347757 VAV1|INPP5D http://www.genome.jp/kegg-bin/show_pathway?hsa04662/hsa:3635%09red/hsa:7409%09red Pertussis KEGG PATHWAY hsa05133 2 75 0.418031591216 0.72401347757 ITGAM|IL23A http://www.genome.jp/kegg-bin/show_pathway?hsa05133/hsa:51561%09red/hsa:3684%09red Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG PATHWAY hsa05412 2 75 0.418031591216 0.72401347757 CACNB2|ITGA7 http://www.genome.jp/kegg-bin/show_pathway?hsa05412/hsa:783%09red/hsa:3679%09red beta-Alanine metabolism KEGG PATHWAY hsa00410 1 29 0.426751761424 0.731574448155 CARNS1 http://www.genome.jp/kegg-bin/show_pathway?hsa00410/hsa:57571%09red Cardiac muscle contraction KEGG PATHWAY hsa04260 2 77 0.43116199104 0.73166883328 CACNB2|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04260/hsa:478%09red/hsa:783%09red Other types of O-glycan biosynthesis KEGG PATHWAY hsa00514 1 30 0.437670775492 0.731806632775 MFNG http://www.genome.jp/kegg-bin/show_pathway?hsa00514/hsa:4242%09red Mucin type O-Glycan biosynthesis KEGG PATHWAY hsa00512 1 31 0.448383427788 0.731806632775 GALNT16 http://www.genome.jp/kegg-bin/show_pathway?hsa00512/hsa:57452%09red Phosphatidylinositol signaling system KEGG PATHWAY hsa04070 2 81 0.456946920908 0.731806632775 INPP5J|INPP5D http://www.genome.jp/kegg-bin/show_pathway?hsa04070/hsa:27124%09red/hsa:3635%09red Propanoate metabolism KEGG PATHWAY hsa00640 1 32 0.458893587791 0.731806632775 LDHC http://www.genome.jp/kegg-bin/show_pathway?hsa00640/hsa:3948%09red RNA polymerase KEGG PATHWAY hsa03020 1 32 0.458893587791 0.731806632775 POLR2J2 http://www.genome.jp/kegg-bin/show_pathway?hsa03020/hsa:246721%09red Huntington's disease KEGG PATHWAY hsa05016 4 183 0.459339953885 0.731806632775 GRIN2B|CREB5|HAP1|POLR2J2 http://www.genome.jp/kegg-bin/show_pathway?hsa05016/hsa:9001%09red/hsa:246721%09red/hsa:9586%09red/hsa:2904%09red Systemic lupus erythematosus KEGG PATHWAY hsa05322 3 135 0.474313617192 0.731806632775 GRIN2B|HIST2H4A|HIST1H2AB http://www.genome.jp/kegg-bin/show_pathway?hsa05322/hsa:2904%09red/hsa:8370%09red/hsa:8335%09red Hypertrophic cardiomyopathy (HCM) KEGG PATHWAY hsa05410 2 84 0.475844121947 0.731806632775 CACNB2|ITGA7 http://www.genome.jp/kegg-bin/show_pathway?hsa05410/hsa:783%09red/hsa:3679%09red Cysteine and methionine metabolism KEGG PATHWAY hsa00270 1 34 0.479321550247 0.731806632775 LDHC http://www.genome.jp/kegg-bin/show_pathway?hsa00270/hsa:3948%09red Natural killer cell mediated cytotoxicity KEGG PATHWAY hsa04650 3 137 0.484070225851 0.731806632775 VAV1|SH2D1A|SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa04650/hsa:25759%09red/hsa:4068%09red/hsa:7409%09red Small cell lung cancer KEGG PATHWAY hsa05222 2 86 0.488221839194 0.731806632775 TRAF1|LAMB4 http://www.genome.jp/kegg-bin/show_pathway?hsa05222/hsa:22798%09red/hsa:7185%09red Salmonella infection KEGG PATHWAY hsa05132 2 87 0.494342836055 0.731806632775 KLC3|CXCL2 http://www.genome.jp/kegg-bin/show_pathway?hsa05132/hsa:147700%09red/hsa:2920%09red Prion diseases KEGG PATHWAY hsa05020 1 36 0.498984202784 0.731806632775 CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa05020/hsa:6352%09red Hematopoietic cell lineage KEGG PATHWAY hsa04640 2 88 0.500417906606 0.731806632775 ITGAM|IL1R1 http://www.genome.jp/kegg-bin/show_pathway?hsa04640/hsa:3554%09red/hsa:3684%09red Protein digestion and absorption KEGG PATHWAY hsa04974 2 88 0.500417906606 0.731806632775 COL27A1|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04974/hsa:478%09red/hsa:85301%09red Prostate cancer KEGG PATHWAY hsa05215 2 89 0.506446581108 0.731806632775 CREB5|INSRR http://www.genome.jp/kegg-bin/show_pathway?hsa05215/hsa:3645%09red/hsa:9586%09red Glycine, serine and threonine metabolism KEGG PATHWAY hsa00260 1 37 0.508537470104 0.731806632775 MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa00260/hsa:4128%09red Salivary secretion KEGG PATHWAY hsa04970 2 90 0.51242842375 0.731806632775 TRPV6|ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04970/hsa:55503%09red/hsa:478%09red Allograft rejection KEGG PATHWAY hsa05330 1 38 0.517909996026 0.731806632775 HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa05330/hsa:3134%09red Dilated cardiomyopathy KEGG PATHWAY hsa05414 2 91 0.518363031549 0.731806632775 CACNB2|ITGA7 http://www.genome.jp/kegg-bin/show_pathway?hsa05414/hsa:783%09red/hsa:3679%09red Pyruvate metabolism KEGG PATHWAY hsa00620 1 41 0.544976737309 0.759588488889 LDHC http://www.genome.jp/kegg-bin/show_pathway?hsa00620/hsa:3948%09red Graft-versus-host disease KEGG PATHWAY hsa05332 1 42 0.553659598297 0.759588488889 HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa05332/hsa:3134%09red Phagosome KEGG PATHWAY hsa04145 3 154 0.563254637694 0.759588488889 CORO1A|HLA-F|ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa04145/hsa:3684%09red/hsa:11151%09red/hsa:3134%09red Type I diabetes mellitus KEGG PATHWAY hsa04940 1 44 0.570535213578 0.759588488889 HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa04940/hsa:3134%09red Valine, leucine and isoleucine degradation KEGG PATHWAY hsa00280 1 44 0.570535213578 0.759588488889 BCKDHA http://www.genome.jp/kegg-bin/show_pathway?hsa00280/hsa:593%09red Proteasome KEGG PATHWAY hsa03050 1 44 0.570535213578 0.759588488889 PSMB9 http://www.genome.jp/kegg-bin/show_pathway?hsa03050/hsa:5698%09red Jak-STAT signaling pathway KEGG PATHWAY hsa04630 3 157 0.576459828172 0.759588488889 IL24|IL23A|SOCS2 http://www.genome.jp/kegg-bin/show_pathway?hsa04630/hsa:8835%09red/hsa:51561%09red/hsa:11009%09red Carbohydrate digestion and absorption KEGG PATHWAY hsa04973 1 45 0.578734086773 0.759588488889 ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04973/hsa:478%09red Vasopressin-regulated water reabsorption KEGG PATHWAY hsa04962 1 45 0.578734086773 0.759588488889 CREB5 http://www.genome.jp/kegg-bin/show_pathway?hsa04962/hsa:9586%09red Sphingolipid metabolism KEGG PATHWAY hsa00600 1 47 0.594668836242 0.770533191993 SPHK1 http://www.genome.jp/kegg-bin/show_pathway?hsa00600/hsa:8877%09red Pyrimidine metabolism KEGG PATHWAY hsa00240 2 105 0.596331680394 0.770533191993 ENTPD1|POLR2J2 http://www.genome.jp/kegg-bin/show_pathway?hsa00240/hsa:953%09red/hsa:246721%09red Notch signaling pathway KEGG PATHWAY hsa04330 1 48 0.602410495578 0.770533191993 MFNG http://www.genome.jp/kegg-bin/show_pathway?hsa04330/hsa:4242%09red N-Glycan biosynthesis KEGG PATHWAY hsa00510 1 49 0.610005443661 0.770533191993 ALG5 http://www.genome.jp/kegg-bin/show_pathway?hsa00510/hsa:29880%09red Amino sugar and nucleotide sugar metabolism KEGG PATHWAY hsa00520 1 49 0.610005443661 0.770533191993 RENBP http://www.genome.jp/kegg-bin/show_pathway?hsa00520/hsa:5973%09red Alzheimer's disease KEGG PATHWAY hsa05010 3 170 0.630758783922 0.786067701935 GRIN2B|GRIN2C|APBB1 http://www.genome.jp/kegg-bin/show_pathway?hsa05010/hsa:2905%09red/hsa:2904%09red/hsa:322%09red Oocyte meiosis KEGG PATHWAY hsa04114 2 112 0.631661546198 0.786067701935 CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04114/hsa:816%09red/hsa:815%09red Staphylococcus aureus infection KEGG PATHWAY hsa05150 1 56 0.659287512963 0.814413986602 ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa05150/hsa:3684%09red Toxoplasmosis KEGG PATHWAY hsa05145 2 119 0.664559545705 0.814934333419 HSPA6|LAMB4 http://www.genome.jp/kegg-bin/show_pathway?hsa05145/hsa:22798%09red/hsa:3310%09red Lysosome KEGG PATHWAY hsa04142 2 122 0.677925457567 0.823488717364 AP3B2|LAMP3 http://www.genome.jp/kegg-bin/show_pathway?hsa04142/hsa:8120%09red/hsa:27074%09red Glycolysis / Gluconeogenesis KEGG PATHWAY hsa00010 1 66 0.719156883445 0.823488717364 LDHC http://www.genome.jp/kegg-bin/show_pathway?hsa00010/hsa:3948%09red Renal cell carcinoma KEGG PATHWAY hsa05211 1 66 0.719156883445 0.823488717364 EGLN2 http://www.genome.jp/kegg-bin/show_pathway?hsa05211/hsa:112398%09red Inflammatory bowel disease (IBD) KEGG PATHWAY hsa05321 1 66 0.719156883445 0.823488717364 IL23A http://www.genome.jp/kegg-bin/show_pathway?hsa05321/hsa:51561%09red Hepatitis C KEGG PATHWAY hsa05160 2 133 0.723283015754 0.823488717364 DDX58|OAS2 http://www.genome.jp/kegg-bin/show_pathway?hsa05160/hsa:4939%09red/hsa:23586%09red Osteoclast differentiation KEGG PATHWAY hsa04380 2 134 0.727129658904 0.823488717364 RELB|IL1R1 http://www.genome.jp/kegg-bin/show_pathway?hsa04380/hsa:5971%09red/hsa:3554%09red Tight junction KEGG PATHWAY hsa04530 2 134 0.727129658904 0.823488717364 RAB3B|PARD6A http://www.genome.jp/kegg-bin/show_pathway?hsa04530/hsa:50855%09red/hsa:5865%09red Epithelial cell signaling in Helicobacter pylori infection KEGG PATHWAY hsa05120 1 68 0.729813607051 0.823488717364 CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa05120/hsa:6352%09red p53 signaling pathway KEGG PATHWAY hsa04115 1 68 0.729813607051 0.823488717364 SESN2 http://www.genome.jp/kegg-bin/show_pathway?hsa04115/hsa:83667%09red PPAR signaling pathway KEGG PATHWAY hsa03320 1 71 0.745050988553 0.823488717364 MMP1 http://www.genome.jp/kegg-bin/show_pathway?hsa03320/hsa:4312%09red Viral myocarditis KEGG PATHWAY hsa05416 1 71 0.745050988553 0.823488717364 HLA-F http://www.genome.jp/kegg-bin/show_pathway?hsa05416/hsa:3134%09red Melanoma KEGG PATHWAY hsa05218 1 71 0.745050988553 0.823488717364 FGF1 http://www.genome.jp/kegg-bin/show_pathway?hsa05218/hsa:2246%09red Adherens junction KEGG PATHWAY hsa04520 1 73 0.754732436559 0.823488717364 PVRL4 http://www.genome.jp/kegg-bin/show_pathway?hsa04520/hsa:81607%09red Chronic myeloid leukemia KEGG PATHWAY hsa05220 1 73 0.754732436559 0.823488717364 SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa05220/hsa:25759%09red Leishmaniasis KEGG PATHWAY hsa05140 1 73 0.754732436559 0.823488717364 ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa05140/hsa:3684%09red Insulin signaling pathway KEGG PATHWAY hsa04910 2 142 0.756312527839 0.823488717364 SHC2|SOCS2 http://www.genome.jp/kegg-bin/show_pathway?hsa04910/hsa:8835%09red/hsa:25759%09red Drug metabolism - cytochrome P450 KEGG PATHWAY hsa00982 1 74 0.759435482213 0.823488717364 MAOA http://www.genome.jp/kegg-bin/show_pathway?hsa00982/hsa:4128%09red Cell adhesion molecules (CAMs) KEGG PATHWAY hsa04514 2 143 0.75976637614 0.823488717364 HLA-F|ITGAM http://www.genome.jp/kegg-bin/show_pathway?hsa04514/hsa:3684%09red/hsa:3134%09red Bacterial invasion of epithelial cells KEGG PATHWAY hsa05100 1 76 0.768574823907 0.827695964207 SHC2 http://www.genome.jp/kegg-bin/show_pathway?hsa05100/hsa:25759%09red Chemical carcinogenesis KEGG PATHWAY hsa05204 1 83 0.797932503913 0.853838602913 CHRNA7 http://www.genome.jp/kegg-bin/show_pathway?hsa05204/hsa:1139%09red Apoptosis KEGG PATHWAY hsa04210 1 88 0.816609826896 0.868293993155 IL1R1 http://www.genome.jp/kegg-bin/show_pathway?hsa04210/hsa:3554%09red GABAergic synapse KEGG PATHWAY hsa04727 1 90 0.823591779858 0.870210182491 HAP1 http://www.genome.jp/kegg-bin/show_pathway?hsa04727/hsa:9001%09red Protein processing in endoplasmic reticulum KEGG PATHWAY hsa04141 2 167 0.83084716281 0.872169335725 ERO1LB|HSPA6 http://www.genome.jp/kegg-bin/show_pathway?hsa04141/hsa:56605%09red/hsa:3310%09red Purine metabolism KEGG PATHWAY hsa00230 2 169 0.835828946737 0.872169335725 ENTPD1|POLR2J2 http://www.genome.jp/kegg-bin/show_pathway?hsa00230/hsa:953%09red/hsa:246721%09red Pancreatic secretion KEGG PATHWAY hsa04972 1 96 0.842994122638 0.87421612718 ATP1A3 http://www.genome.jp/kegg-bin/show_pathway?hsa04972/hsa:478%09red Chagas disease (American trypanosomiasis) KEGG PATHWAY hsa05142 1 105 0.868197485138 0.894829309835 CCL5 http://www.genome.jp/kegg-bin/show_pathway?hsa05142/hsa:6352%09red Axon guidance KEGG PATHWAY hsa04360 1 129 0.917441778646 0.936097850578 EPHB2 http://www.genome.jp/kegg-bin/show_pathway?hsa04360/hsa:2048%09red Spliceosome KEGG PATHWAY hsa03040 1 131 0.920604488823 0.936097850578 HSPA6 http://www.genome.jp/kegg-bin/show_pathway?hsa03040/hsa:3310%09red MicroRNAs in cancer KEGG PATHWAY hsa05206 3 296 0.924953828548 0.936097850578 CYP24A1|HMGA2|MMP9 http://www.genome.jp/kegg-bin/show_pathway?hsa05206/hsa:4318%09red/hsa:8091%09red/hsa:1591%09red Metabolic pathways KEGG PATHWAY hsa01100 16 1182 0.953046553231 0.958753418819 GALNT16|SPHK1|IDO1|INPP5J|ALG5|MAOA|CYP24A1|FUT3|POLR2J2|BCKDHA|PLA2G4C|HGD|CYP4F3|CYP4F2|PLA2G4E|LDHC http://www.genome.jp/kegg-bin/show_pathway?hsa01100/hsa:123745%09red/hsa:3948%09red/hsa:3620%09red/hsa:593%09red/hsa:2525%09red/hsa:8877%09red/hsa:27124%09red/hsa:4051%09red/hsa:57452%09red/hsa:29880%09red/hsa:8605%09red/hsa:8529%09red/hsa:1591%09red/hsa:246721%09red/hsa:4128%09red/hsa:3081%09red Olfactory transduction KEGG PATHWAY hsa04740 3 406 0.985571123786 0.985571123786 CNGA4|CAMK2A|CAMK2B http://www.genome.jp/kegg-bin/show_pathway?hsa04740/hsa:816%09red/hsa:1262%09red/hsa:815%09red -------------------- #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink -------------------- #Term Database ID Input number Background number P-Value Corrected P-Value Input Hyperlink --------------------