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. 2019 Mar 11;294(18):7377–7387. doi: 10.1074/jbc.RA118.006083

Figure 2.

Figure 2.

Potency and structure–activity relationship analysis of mAQP3 and hAQP3 inhibition, respectively, by commercially available hit analogues. Shown is t½ of cell shrinking, indicating that water permeability was measured in calcein-loaded, m/hAQP3-expressing CHO cells. No clear potency differences between mAQP3 and hAQP3 inhibition were observed. Error bars indicate standard deviation.