Chemical suppression of specific C-C chemokine signaling pathways enhances cardiac reprogramming

Supporting Information

  • Supplement and figures - Supplement figures and tables
  • Movie 1.IMAP-Beating - Showing spontaneous beating of iCMs derived from neonatal cardiac fibroblasts (NCFs) in MGT+IMAP group group
  • Movie 2.DMSO-Beating - Showing spontaneous beating of iCMs derived from NCFs in MGT+DMSO group group
  • Movie 3.IMAP-Rhod3 - Showing calcium transient activities in MGT+IMAP group using Rhod3 staining
  • Movie 4.DMSO-Rhod3 - Showing calcium transient activities in MGT+DMSO group using Rhod3 staining
  • Movie 5.IMAP-White-Beating - Linage-tracing system showing spontaneous beating of iCMs (green) derived from neonatal cardiac fibroblasts (NCFs) in MGT+IMAP group under bright field.
  • Movie 6.IMAP-Green-Beating - Linage-tracing system showing spontaneous beating of iCMs (green) derived from neonatal cardiac fibroblasts (NCFs) in MGT+IMAP group under fluorescence microscope.
  • Movie 7.IMAP Ca2+ - Showing calcium transient activities in MGT+IMAP group using αMHC-Cre/Rosa26A-Flox-Stop-Flox-GCaMP3 NCFs.
  • Movie 8.DMSO Ca2+ - Showing calcium transient activities in MGT+DMSO group using αMHC-Cre/Rosa26A-Flox-Stop-Flox-GCaMP3 NCFs.