GWAS trait name,MR associations with GWAS p <= 5x10^-8,MR associations with all GWAS Standing height,109,146 Sitting height,73,105 Trunk fat-free mass,71,102 Trunk predicted mass,71,102 Whole body fat-free mass,62,94 Impedance of whole body,61,98 Whole body water mass,59,95 Arm predicted mass (right),56,93 Leg fat-free mass (left),56,86 Leg predicted mass (left),56,88 Arm fat-free mass (right),55,89 Basal metabolic rate,55,83 Arm fat-free mass (left),53,87 Impedance of arm (right),51,83 Impedance of leg (right),51,86 Leg predicted mass (right),50,80 Arm predicted mass (left),49,79 Leg fat-free mass (right),49,81 Impedance of arm (left),46,73 Impedance of leg (left),43,87 Weight,40,66 Hip circumference,38,61 Whole body fat mass,38,51 Forced vital capacity (FVC),37,61 Body mass index (BMI),35,53 Trunk fat mass,35,59 Arm fat mass (right),34,58 Body fat percentage,32,54 Leg fat mass (right),32,50 Arm fat percentage (left),31,53 Arm fat percentage (right),31,51 Arm fat mass (left),30,53 Leg fat percentage (right),30,44 "Forced vital capacity (FVC), Best measure",29,52 Leg fat mass (left),29,49 Leg fat percentage (left),29,42 Trunk fat percentage,28,60 Waist circumference,27,45 "Heel bone mineral density (BMD) T-score, automated",26,39 "Diastolic blood pressure, automated reading",25,45 "Forced expiratory volume in 1-second (FEV1), Best measure",25,33 "Forced expiratory volume in 1-second (FEV1), predicted percentage",25,31 Hand grip strength (left),23,39 Hand grip strength (right),23,42 "Pulse rate, automated reading",22,43 Qualifications: College or University degree,22,40 Forced expiratory volume in 1-second (FEV1),21,39 "Systolic blood pressure, automated reading",19,41 "Forced expiratory volume in 1-second (FEV1), predicted",16,27 "Non-cancer illness code, self-reported: hypertension",15,34 Peak expiratory flow (PEF),14,21 Hair/balding pattern: Pattern 4,13,16 Vascular/heart problems diagnosed by doctor: High blood pressure,13,34 "Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: None of the above",12,17 "Heel bone mineral density (BMD) T-score, automated (left)",12,18 "Heel bone mineral density (BMD) T-score, automated (right)",12,19 Vascular/heart problems diagnosed by doctor: None of the above,12,33 "Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Hayfever, allergic rhinitis or eczema",11,17 "Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Asthma",9,14 Qualifications: None of the above,9,15 "Medication for pain relief, constipation, heartburn: None of the above",8,12 "Medication for pain relief, constipation, heartburn: Paracetamol",8,11 Nervous feelings,8,18 "Non-cancer illness code, self-reported: asthma",8,12 BMI,7,8 Fed-up feelings,7,12 "Non-cancer illness code, self-reported: malabsorption/coeliac disease",7,8 Pain type(s) experienced in last month: Headache,7,11 Birth weight,6,14 Diabetes diagnosed by doctor,6,8 Doctor diagnosed asthma,6,11 Miserableness,6,7 Mood swings,6,8 "Non-cancer illness code, self-reported: high cholesterol",6,11 "Non-cancer illness code, self-reported: hypothyroidism/myxoedema",6,12 Sensitivity / hurt feelings,6,9 Hair/balding pattern: Pattern 3,5,6 Irritability,5,8 Mouth/teeth dental problems: Mouth ulcers,5,11 Treatment/medication code: salbutamol,5,5 Worrier / anxious feelings,5,18 Creatinine (enzymatic) in urine,4,7 Mouth/teeth dental problems: Dentures,4,5 "Non-cancer illness code, self-reported: diabetes",4,6 "Non-cancer illness code, self-reported: ulcerative colitis",4,6 Number of incorrect matches in round,4,5 Pulse rate,4,10 Treatment/medication code: paracetamol,4,11 Wheeze or whistling in the chest in last year,4,7 Had menopause,3,6 Mean time to correctly identify matches,3,11 "Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Blood pressure medication",3,11 "Medication for cholesterol, blood pressure or diabetes: Cholesterol lowering medication",3,9 Qualifications: A levels/AS levels or equivalent,3,6 Snoring,3,10 T2D,3,5 Treatment/medication code: beclometasone,3,5 Treatment/medication code: becotide 50 inhaler,3,5 Treatment/medication code: seretide 50 evohaler,3,4 Age at last live birth,2,2 Alcohol usually taken with meals,2,3 "Cancer code, self-reported: breast cancer",2,4 Eye problems/disorders: Glaucoma,2,2 Illnesses of mother: Parkinson's disease,2,3 "Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Insulin",2,2 "Medication for cholesterol, blood pressure or diabetes: None of the above",2,4 "Non-cancer illness code, self-reported: enlarged prostate",2,3 "Non-cancer illness code, self-reported: hyperthyroidism/thyrotoxicosis",2,4 Pain type(s) experienced in last month: Knee pain,2,2 "Reason for glasses/contact lenses: For short-sightedness, i.e. only or mainly for distance viewing such as driving, cinema etc (called 'myopia')",2,2 Started insulin within one year diagnosis of diabetes,2,3 Treatment/medication code: amlodipine,2,4 Treatment/medication code: atorvastatin,2,2 Treatment/medication code: insulin product,2,3 Treatment/medication code: levothyroxine sodium,2,7 Treatment/medication code: simvastatin,2,4 Treatment/medication code: ventolin 100micrograms inhaler,2,5 "Types of physical activity in last 4 weeks: Light DIY (eg: pruning, watering the lawn)",2,2 Waist,2,5 Waist adjusted for BMI,2,4 Weight (men),2,6 Weight (women),2,2 Age at first live birth,1,4 Bilateral oophorectomy (both ovaries removed),1,2 Doctor diagnosed hayfever or allergic rhinitis,1,2 Ever smoked,1,6 Fasting Glucose,1,1 Illnesses of father: Diabetes,1,2 Illnesses of father: Lung cancer,1,2 Illnesses of mother: High blood pressure,1,3 Illnesses of siblings: Diabetes,1,3 Maternal smoking around birth,1,7 "Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Cholesterol lowering medication",1,4 "Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: None of the above",1,3 "Medication for cholesterol, blood pressure or diabetes: Blood pressure medication",1,5 "Medication for cholesterol, blood pressure or diabetes: Insulin",1,2 Mineral and other dietary supplements: Calcium,1,1 "Non-cancer illness code, self-reported: angina",1,1 "Non-cancer illness code, self-reported: glaucoma",1,1 "Non-cancer illness code, self-reported: gout",1,3 "Non-cancer illness code, self-reported: hayfever/allergic rhinitis",1,2 "Non-cancer illness code, self-reported: heart attack/myocardial infarction",1,1 "Non-cancer illness code, self-reported: rheumatoid arthritis",1,1 Potassium in urine,1,1 Qualifications: O levels/GCSEs or equivalent,1,2 "Seen doctor (GP) for nerves, anxiety, tension or depression",1,2 Smoking status: Previous,1,3 Tense / 'highly strung',1,7 Treatment/medication code: allopurinol,1,1 Treatment/medication code: lipitor 10mg tablet,1,1 Treatment/medication code: methotrexate,1,1 Treatment/medication code: thyroxine product,1,1 "Types of physical activity in last 4 weeks: Other exercises (eg: swimming, cycling, keep fit, bowling)",1,5 Vascular/heart problems diagnosed by doctor: Angina,1,1 Vascular/heart problems diagnosed by doctor: Heart attack,1,1 Vitamin and mineral supplements: Folic acid or Folate (Vit B9),1,3 Vitamin and mineral supplements: Multivitamins +/- minerals,1,2 Worry too long after embarrassment,1,3 Alcohol drinker status: Previous,0,1 Breastfed as a baby,0,1 "Cancer code, self-reported: cervical cancer",0,2 Chest pain or discomfort,0,1 Current employment status: In paid employment or self-employed,0,1 Ever highly irritable/argumentative for 2 days,0,1 Eye problems/disorders: Diabetes related eye disease,0,2 Eye problems/disorders: Other serious eye condition,0,1 Father's age at death,0,2 Fractured bone site(s): Other bones,0,1 Fractured bone site(s): Wrist,0,1 Fractured/broken bones in last 5 years,0,1 Guilty feelings,0,7 Handedness (chirality/laterality): Left-handed,0,2 Headaches for 3+ months,0,1 Hearing difficulty/problems with background noise,0,2 Hearing difficulty/problems: Yes,0,1 Illnesses of father: Bowel cancer,0,1 Illnesses of father: Heart disease,0,1 Illnesses of mother: Chronic bronchitis/emphysema,0,1 Illnesses of mother: Diabetes,0,2 Illnesses of siblings: High blood pressure,0,2 "Illness, injury, bereavement, stress in last 2 years: Financial difficulties",0,3 Leg pain in calf/calves,0,1 Leg pain on walking,0,1 "Long-standing illness, disability or infirmity",0,2 "Medication for pain relief, constipation, heartburn: Omeprazole (e.g. Zanprol)",0,1 Mineral and other dietary supplements: Glucosamine,0,1 Mouth/teeth dental problems: None of the above,0,3 "Non-cancer illness code, self-reported: cholelithiasis/gall stones",0,1 "Non-cancer illness code, self-reported: duodenal ulcer",0,1 "Non-cancer illness code, self-reported: epilepsy",0,1 "Non-cancer illness code, self-reported: kidney stone/ureter stone/bladder stone",0,1 "Non-cancer illness code, self-reported: nasal polyps",0,3 "Non-cancer illness code, self-reported: pulmonary embolism +/- dvt",0,1 Pain type(s) experienced in last month: Hip pain,0,3 Pain type(s) experienced in last month: Neck or shoulder pain,0,1 Pain type(s) experienced in last month: None of the above,0,1 Pulse wave reflection index,0,1 "Qualifications: Other professional qualifications eg: nursing, teaching",0,1 Risk taking,0,2 "Seen a psychiatrist for nerves, anxiety, tension or depression",0,2 Smoking status: Current,0,3 Suffer from 'nerves',0,1 "Tinnitus: Yes, but not now, but have in the past",0,2 Transport type for commuting to job workplace: Cycle,0,1 Transport type for commuting to job workplace: Public transport,0,1 Treatment/medication code: bendroflumethiazide,0,2 Treatment/medication code: doxazosin,0,1 Treatment/medication code: folic acid product,0,1 Treatment/medication code: gliclazide,0,1 Treatment/medication code: lisinopril,0,1 Treatment/medication code: metformin,0,3 Treatment/medication code: pravastatin,0,1 Treatment/medication code: quinine,0,1 Treatment/medication code: qvar 50 inhaler,0,4 Treatment/medication code: ramipril,0,1 Treatment/medication code: symbicort 100/6 turbohaler,0,4 "Types of physical activity in last 4 weeks: Heavy DIY (eg: weeding, lawn mowing, carpentry, digging)",0,1 Types of physical activity in last 4 weeks: Walking for pleasure (not as a means of transport),0,2 Types of transport used (excluding work): Car/motor vehicle,0,2 Types of transport used (excluding work): Cycle,0,3 Used an inhaler for chest within last hour,0,4 Vitamin and mineral supplements: Vitamin B,0,1 Which eye(s) affected by myopia (short sight): Right eye,0,1