GWAS trait name,MR associations with GWAS p <= 5x10^-8,MR associations with all GWAS
Standing height,1157,1534
Sitting height,900,1179
Trunk predicted mass,772,1047
Trunk fat-free mass,768,1057
Whole body fat-free mass,683,1009
Whole body water mass,682,1008
Impedance of whole body,645,931
Arm fat-free mass (right),609,925
Arm predicted mass (right),608,901
Impedance of leg (left),601,843
Basal metabolic rate,595,918
Arm predicted mass (left),593,917
Impedance of leg (right),589,821
Arm fat-free mass (left),573,884
Impedance of arm (right),550,865
Impedance of arm (left),548,814
Leg fat-free mass (right),542,820
Leg predicted mass (left),537,794
Leg predicted mass (right),535,814
Leg fat-free mass (left),529,799
Weight,478,761
Hip circumference,424,629
Body mass index (BMI),406,623
"Heel bone mineral density (BMD) T-score, automated",396,508
Forced vital capacity (FVC),363,514
Trunk fat mass,363,575
Whole body fat mass,341,555
Leg fat mass (left),330,554
Leg fat mass (right),324,523
Body fat percentage,312,516
Arm fat mass (left),308,510
Arm fat percentage (left),306,480
"Forced vital capacity (FVC), Best measure",306,461
Trunk fat percentage,296,556
Arm fat mass (right),293,511
"Diastolic blood pressure, automated reading",287,459
Arm fat percentage (right),284,452
Leg fat percentage (right),262,442
Leg fat percentage (left),261,475
"Systolic blood pressure, automated reading",259,388
Waist circumference,241,421
Forced expiratory volume in 1-second (FEV1),225,411
"Non-cancer illness code, self-reported: hypertension",223,337
Vascular/heart problems diagnosed by doctor: High blood pressure,219,382
"Pulse rate, automated reading",217,350
"Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: None of the above",206,286
"Forced expiratory volume in 1-second (FEV1), Best measure",203,352
"Heel bone mineral density (BMD) T-score, automated (right)",196,283
Vascular/heart problems diagnosed by doctor: None of the above,192,314
Hand grip strength (left),191,293
"Heel bone mineral density (BMD) T-score, automated (left)",191,277
Hand grip strength (right),185,282
Peak expiratory flow (PEF),159,257
Qualifications: College or University degree,155,283
"Non-cancer illness code, self-reported: asthma",152,224
"Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Asthma",148,215
"Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Hayfever, allergic rhinitis or eczema",144,234
"Forced expiratory volume in 1-second (FEV1), predicted percentage",138,205
Worrier / anxious feelings,119,172
"Non-cancer illness code, self-reported: hypothyroidism/myxoedema",100,159
Diabetes diagnosed by doctor,95,132
"Non-cancer illness code, self-reported: malabsorption/coeliac disease",93,94
Irritability,92,135
Hair/balding pattern: Pattern 4,91,144
"Forced expiratory volume in 1-second (FEV1), predicted",89,144
"Medication for pain relief, constipation, heartburn: None of the above",87,119
Treatment/medication code: levothyroxine sodium,82,117
"Medication for pain relief, constipation, heartburn: Paracetamol",81,104
Mouth/teeth dental problems: Dentures,78,106
Nervous feelings,75,134
"Non-cancer illness code, self-reported: hyperthyroidism/thyrotoxicosis",73,83
Miserableness,67,112
"Non-cancer illness code, self-reported: high cholesterol",67,105
Birth weight,66,120
"Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Blood pressure medication",66,127
Treatment/medication code: insulin product,66,83
Pulse rate,65,101
"Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Insulin",63,72
Mouth/teeth dental problems: Mouth ulcers,59,108
"Medication for cholesterol, blood pressure or diabetes: Insulin",57,70
Doctor diagnosed asthma,55,66
Qualifications: None of the above,55,97
"Non-cancer illness code, self-reported: diabetes",54,93
Wheeze or whistling in the chest in last year,52,83
Started insulin within one year diagnosis of diabetes,51,61
"Long-standing illness, disability or infirmity",45,53
Qualifications: A levels/AS levels or equivalent,45,85
"Medication for cholesterol, blood pressure or diabetes: None of the above",44,70
"Medication for cholesterol, blood pressure or diabetes: Blood pressure medication",42,80
Mood swings,42,84
Mean time to correctly identify matches,40,66
Fed-up feelings,38,64
Treatment/medication code: ventolin 100micrograms inhaler,38,55
Treatment/medication code: paracetamol,37,70
Worry too long after embarrassment,37,64
Potassium in urine,36,75
"Non-cancer illness code, self-reported: gout",34,36
"Medication for cholesterol, blood pressure or diabetes: Cholesterol lowering medication",31,80
Treatment/medication code: thyroxine product,31,42
Pain type(s) experienced in last month: Headache,30,69
Treatment/medication code: allopurinol,30,37
Had menopause,29,32
"Seen a psychiatrist for nerves, anxiety, tension or depression",29,36
Sensitivity / hurt feelings,28,63
Hair/balding pattern: Pattern 3,26,36
"Non-cancer illness code, self-reported: eczema/dermatitis",26,32
Hearing difficulty/problems with background noise,23,49
"Non-cancer illness code, self-reported: rheumatoid arthritis",23,28
"Seen doctor (GP) for nerves, anxiety, tension or depression",23,40
Maximum heart rate during fitness test,22,23
Treatment/medication code: simvastatin,21,50
Suffer from 'nerves',20,49
Alcohol usually taken with meals,19,44
"Non-cancer illness code, self-reported: hayfever/allergic rhinitis",18,33
Tense / 'highly strung',18,58
Creatinine (enzymatic) in urine,17,37
Hair/balding pattern: Pattern 2,17,33
Hearing difficulty/problems: Yes,16,32
"Non-cancer illness code, self-reported: psoriasis",16,25
Age at first live birth,15,24
Doctor diagnosed hayfever or allergic rhinitis,15,26
Number of incorrect matches in round,15,43
Pain type(s) experienced in last month: Knee pain,15,25
Sodium in urine,15,34
Treatment/medication code: metformin,15,35
BMI,14,27
Ever smoked,14,50
Waist adjusted for BMI,14,25
"Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Cholesterol lowering medication",13,33
"Non-cancer illness code, self-reported: ulcerative colitis",13,18
Illnesses of siblings: Diabetes,12,24
"Non-cancer illness code, self-reported: angina",12,16
Snoring,12,45
Treatment/medication code: bendroflumethiazide,12,31
Treatment/medication code: atorvastatin,11,15
"Cancer code, self-reported: breast cancer",10,16
Illnesses of father: Heart disease,10,19
Illnesses of mother: Breast cancer,10,10
"Non-cancer illness code, self-reported: uterine fibroids",10,10
Age at last live birth,9,15
"Cancer code, self-reported: basal cell carcinoma",9,13
Cancer diagnosed by doctor,9,13
Eye problems/disorders: Diabetes related eye disease,9,23
Mouth/teeth dental problems: None of the above,9,34
"Non-cancer illness code, self-reported: glaucoma",9,11
"Non-cancer illness code, self-reported: prolapsed disc/slipped disc",9,13
Pain type(s) experienced in last month: Back pain,9,16
T2D,9,20
Treatment/medication code: amlodipine,9,20
Treatment/medication code: beclometasone,9,11
Vascular/heart problems diagnosed by doctor: Angina,9,13
Eye problems/disorders: Glaucoma,8,12
Illnesses of father: Lung cancer,8,14
Illnesses of siblings: High blood pressure,8,20
"Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: None of the above",8,34
"Medication for pain relief, constipation, heartburn: Aspirin",8,17
"Non-cancer illness code, self-reported: bronchitis",8,13
Treatment/medication code: aspirin,8,15
Treatment/medication code: seretide 50 evohaler,8,14
"Types of physical activity in last 4 weeks: Other exercises (eg: swimming, cycling, keep fit, bowling)",8,32
Bring up phlegm/sputum/mucus on most days,7,8
"Cancer code, self-reported: prostate cancer",7,10
Illnesses of father: High blood pressure,7,12
"Loneliness, isolation",7,15
"Non-cancer illness code, self-reported: enlarged prostate",7,38
"Non-cancer illness code, self-reported: kidney stone/ureter stone/bladder stone",7,9
Treatment/medication code: folic acid product,7,11
Treatment/medication code: methotrexate,7,12
"Types of physical activity in last 4 weeks: Light DIY (eg: pruning, watering the lawn)",7,11
Vitamin and mineral supplements: Folic acid or Folate (Vit B9),7,8
"Non-cancer illness code, self-reported: heart attack/myocardial infarction",6,11
"Non-cancer illness code, self-reported: migraine",6,11
"Non-cancer illness code, self-reported: osteoporosis",6,8
Proinsulin,6,7
Smoking status: Previous,6,17
Treatment/medication code: atenolol,6,9
Types of transport used (excluding work): Cycle,6,15
Vascular/heart problems diagnosed by doctor: Heart attack,6,12
Fasting Glucose,5,6
Illnesses of father: Diabetes,5,7
Illnesses of mother: High blood pressure,5,20
Maternal smoking around birth,5,26
"Medication for pain relief, constipation, heartburn: Ibuprofen (e.g. Nurofen)",5,7
Vitamin and mineral supplements: Multivitamins +/- minerals,5,9
Waist,5,11
Bilateral oophorectomy (both ovaries removed),4,5
Guilty feelings,4,52
Hearing aid user,4,8
Illnesses of mother: Diabetes,4,10
"Non-cancer illness code, self-reported: atrial fibrillation",4,9
"Non-cancer illness code, self-reported: cholelithiasis/gall stones",4,14
"Non-cancer illness code, self-reported: nasal polyps",4,10
Qualifications: O levels/GCSEs or equivalent,4,9
Treatment/medication code: lipitor 10mg tablet,4,6
Treatment/medication code: prednisolone,4,4
Weight (women),4,12
"Cancer code, self-reported: malignant melanoma",3,11
Fractured/broken bones in last 5 years,3,6
Illnesses of father: Chronic bronchitis/emphysema,3,4
Illnesses of mother: Parkinson's disease,3,11
Proinsulin adjusted for BMI,3,6
"Qualifications: Other professional qualifications eg: nursing, teaching",3,26
"Reason for glasses/contact lenses: For short-sightedness, i.e. only or mainly for distance viewing such as driving, cinema etc (called 'myopia')",3,18
Risk taking,3,26
Smoking status: Current,3,22
Treatment/medication code: becotide 50 inhaler,3,10
Treatment/medication code: ibuprofen,3,4
Treatment/medication code: rosuvastatin,3,4
"Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the leg (DVT)",2,9
"Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the lung",2,2
Ever used hormone-replacement therapy (HRT),2,9
Father still alive,2,2
Fractured bone site(s): Wrist,2,4
Illnesses of father: Prostate cancer,2,3
Illnesses of mother: Chronic bronchitis/emphysema,2,4
Illnesses of mother: Heart disease,2,2
Illnesses of siblings: Breast cancer,2,9
"Light smokers, at least 100 smokes in lifetime",2,2
Mineral and other dietary supplements: Calcium,2,6
"Non-cancer illness code, self-reported: deep venous thrombosis (dvt)",2,4
"Non-cancer illness code, self-reported: pulmonary embolism +/- dvt",2,2
Pain type(s) experienced in last month: None of the above,2,16
Treatment/medication code: doxazosin,2,6
Treatment/medication code: ramipril,2,7
Treatment/medication code: salbutamol,2,9
Types of physical activity in last 4 weeks: Walking for pleasure (not as a means of transport),2,14
Types of transport used (excluding work): Walk,2,9
Weight (men),2,18
Duration of vigorous activity,1,1
Father's age at death,1,15
Fractured bone site(s): Ankle,1,1
Handedness (chirality/laterality): Left-handed,1,11
Illnesses of father: Alzheimer's disease/dementia,1,1
Illnesses of mother: Alzheimer's disease/dementia,1,5
Illnesses of mother: Lung cancer,1,1
Illnesses of siblings: Heart disease,1,1
Illnesses of siblings: Severe depression,1,1
Mineral and other dietary supplements: Fish oil (including cod liver oil),1,4
Mouth/teeth dental problems: Bleeding gums,1,2
"Non-cancer illness code, self-reported: hiatus hernia",1,3
Townsend deprivation index at recruitment,1,1
Treatment/medication code: ezetimibe,1,3
Treatment/medication code: gliclazide,1,3
Treatment/medication code: quinine,1,3
"Types of physical activity in last 4 weeks: Heavy DIY (eg: weeding, lawn mowing, carpentry, digging)",1,2
Types of physical activity in last 4 weeks: None of the above,1,3
Types of physical activity in last 4 weeks: Strenuous sports,1,2
Adopted as a child,0,1
Age started oral contraceptive pill,0,1
Alcohol drinker status: Never,0,1
Alcohol drinker status: Previous,0,1
Breastfed as a baby,0,6
"Cancer code, self-reported: cervical cancer",0,2
Chest pain due to walking ceases when standing still,0,1
Chest pain or discomfort,0,12
Cough on most days,0,1
Current employment status: In paid employment or self-employed,0,2
Current employment status: Retired,0,5
Current employment status: Unable to work because of sickness or disability,0,1
Duration of walks,0,4
Ever depressed for a whole week,0,1
Ever had prostate specific antigen (PSA) test,0,7
Ever highly irritable/argumentative for 2 days,0,8
Ever unenthusiastic/disinterested for a whole week,0,3
Eye problems/disorders: None of the above,0,1
Eye problems/disorders: Other serious eye condition,0,1
Fasting Insulin,0,15
Former alcohol drinker,0,1
Fractured bone site(s): Arm,0,2
Fractured bone site(s): Other bones,0,1
Handedness (chirality/laterality): Use both right and left hands equally,0,2
Headaches for 3+ months,0,10
HOMA IR,0,5
Illnesses of father: Bowel cancer,0,2
Illnesses of siblings: Chronic bronchitis/emphysema,0,3
Illnesses of siblings: Prostate cancer,0,2
Illnesses of siblings: Stroke,0,1
"Illness, injury, bereavement, stress in last 2 years: Financial difficulties",0,6
"Illness, injury, bereavement, stress in last 2 years: None of the above",0,2
Leg pain in calf/calves,0,1
Leg pain on walking,0,10
Leg pain when standing still or sitting,0,1
Manic/hyper symptoms: I needed less sleep than usual,0,1
Manic/hyper symptoms: I was more talkative than usual,0,1
"Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Oral contraceptive pill or minipill",0,4
"Medication for pain relief, constipation, heartburn: Ranitidine (e.g. Zantac)",0,1
Mineral and other dietary supplements: Glucosamine,0,4
Mineral and other dietary supplements: Iron,0,1
Mineral and other dietary supplements: Selenium,0,1
Mineral and other dietary supplements: Zinc,0,2
Mouth/teeth dental problems: Loose teeth,0,8
Mouth/teeth dental problems: Toothache,0,1
"Non-cancer illness code, self-reported: breast cysts",0,1
"Non-cancer illness code, self-reported: chronic sinusitis",0,2
"Non-cancer illness code, self-reported: depression",0,2
"Non-cancer illness code, self-reported: ear/vestibular disorder",0,1
"Non-cancer illness code, self-reported: endometriosis",0,3
"Non-cancer illness code, self-reported: epilepsy",0,2
"Non-cancer illness code, self-reported: irritable bowel syndrome",0,2
"Non-cancer illness code, self-reported: osteoarthritis",0,3
"Non-cancer illness code, self-reported: tonsiltis",0,1
"Non-cancer illness code, self-reported: vaginal prolapse/uterine prolapse",0,3
No-wear time bias adjusted acceleration standard deviation,0,2
Other eye problems,0,2
Pain type(s) experienced in last month: Hip pain,0,7
Pain type(s) experienced in last month: Neck or shoulder pain,0,11
Pain type(s) experienced in last month: Pain all over the body,0,1
Pain type(s) experienced in last month: Stomach or abdominal pain,0,4
Part of a multiple birth,0,2
Pulse wave reflection index,0,5
Qualifications: CSEs or equivalent,0,1
Reason for glasses/contact lenses: For a 'lazy' eye or an eye with poor vision since childhood (called 'amblyopia'),0,1
Reason for glasses/contact lenses: For just reading/near work as you are getting older (called 'presbyopia'),0,1
"Reason for glasses/contact lenses: For long-sightedness, i.e. for distance and near, but particularly for near tasks like reading (called 'hypermetropia')",0,2
Time employed in main current job,0,3
"Tinnitus: Yes, now most or all of the time",0,1
Tobacco smoking: Ex-smoker,0,6
Transport type for commuting to job workplace: Cycle,0,2
Transport type for commuting to job workplace: Public transport,0,3
Transport type for commuting to job workplace: Walk,0,1
Treatment/medication code: adcal-d3 1.5g/10micrograms chewable tablet,0,1
Treatment/medication code: alendronate sodium,0,4
Treatment/medication code: beconase 50micrograms nasal spray,0,2
Treatment/medication code: cetirizine,0,1
Treatment/medication code: chondroitin product,0,1
Treatment/medication code: co-codamol,0,2
Treatment/medication code: cod liver oil capsule,0,1
Treatment/medication code: felodipine,0,20
Treatment/medication code: ferrous sulphate,0,1
Treatment/medication code: flixonase 50micrograms aqueous nasal spray,0,2
Treatment/medication code: garlic product,0,2
Treatment/medication code: lisinopril,0,1
Treatment/medication code: perindopril,0,1
Treatment/medication code: qvar 50 inhaler,0,7
Treatment/medication code: symbicort 100/6 turbohaler,0,4
Used an inhaler for chest within last hour,0,3
Vitamin and mineral supplements: Vitamin B,0,2
Vitamin and mineral supplements: Vitamin C,0,3