This PDF file includes:

• Fig. S1. Characterization of the modified dendrimers by ¹H NMR.
• Fig. S2. Cytosolic delivery of BSA.
• Fig. S3. Characterization of the BSA-FITC/dendrimer-RBITC complex by FRET.
• Fig. S4. Confocal images of HeLa cells treated with the BSA-FITC/P4 complex at different times.
• Fig. S5. Characterization of the protein/dendrimer complexes by DLS and TEM.
• Fig. S6. Enzyme activity of β-Gal, HRP, and RNase A.
• Fig. S7. CRISPR-Cas9 gene editing in different cells.
• Table S1. Sequences of sgRNA used in this study.
• Table S2. Primer sequences for PCR amplification of target genes.

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