Gene,Mutation,Drug,Observed in 17k samples with WGS 

rrs,r.1158g>t,amikacin,No

rrs,r.1338a>c,amikacin,Yes

rrs,r.1401a>g,amikacin,Yes

rrs,r.1402c>a,amikacin,Yes

rrs,r.1402c>t,amikacin,Yes

rrs,r.1484g>t,amikacin,Yes

rrs,r.1158g>t,aminoglycosides,No

rrs,r.1338a>c,aminoglycosides,Yes

rrs,r.1401a>g,aminoglycosides,Yes

rrs,r.1402c>a,aminoglycosides,Yes

rrs,r.1402c>t,aminoglycosides,Yes

rrs,r.1484g>t,aminoglycosides,Yes

Rv0678,c.192_193insG,bedaquiline,No

Rv0678,c.38_39insA,bedaquiline,No

Rv0678,p.Arg134*,bedaquiline,No

Rv0678,p.Arg94Gln,bedaquiline,No

Rv0678,p.Glu138Gly,bedaquiline,No

Rv0678,p.Ser63Arg,bedaquiline,No

Rv0678,p.Ser68Gly,bedaquiline,No

rrs,r.1401a>g,capreomycin,Yes

rrs,r.1402c>a,capreomycin,Yes

rrs,r.1402c>t,capreomycin,Yes

rrs,r.1484g>t,capreomycin,Yes

tlyA,c.198_199insGC,capreomycin,No

tlyA,c.23del,capreomycin,No

tlyA,c.26del,capreomycin,No

tlyA,c.310del,capreomycin,No

tlyA,c.400del,capreomycin,No

tlyA,c.477del,capreomycin,No

tlyA,c.586del,capreomycin,No

tlyA,c.653del,capreomycin,No

tlyA,c.673_674del,capreomycin,No

tlyA,c.67_69del,capreomycin,No

tlyA,c.733_742del,capreomycin,No

tlyA,c.751_752insTG,capreomycin,No

tlyA,c.758del,capreomycin,No

tlyA,frameshift,capreomycin,No

tlyA,p.Ala67Glu,capreomycin,No

tlyA,p.Ala91Glu,capreomycin,No

tlyA,p.Arg14Trp,capreomycin,No

tlyA,p.Arg18*,capreomycin,No

tlyA,p.Arg3*,capreomycin,No

tlyA,p.Asn236Lys,capreomycin,Yes

tlyA,p.Gln184*,capreomycin,No

tlyA,p.Gln22*,capreomycin,No

tlyA,p.Glu238Lys,capreomycin,No

tlyA,p.Leu118Pro,capreomycin,No

tlyA,p.Leu150Pro,capreomycin,No

tlyA,p.Lys69Glu,capreomycin,No

tlyA,p.Phe185Leu,capreomycin,No

tlyA,p.Pro183Leu,capreomycin,No

tlyA,p.Val128Glu,capreomycin,No

gyrA,p.Ala74Ser,ciprofloxacin,Yes

gyrA,p.Ala90Glu,ciprofloxacin,Yes

gyrA,p.Ala90Gly,ciprofloxacin,Yes

gyrA,p.Ala90Val,ciprofloxacin,Yes

gyrA,p.Arg68Gly,ciprofloxacin,No

gyrA,p.Asp89Asn,ciprofloxacin,Yes

gyrA,p.Asp94Ala,ciprofloxacin,Yes

gyrA,p.Asp94Asn,ciprofloxacin,Yes

gyrA,p.Asp94Gly,ciprofloxacin,Yes

gyrA,p.Asp94His,ciprofloxacin,Yes

gyrA,p.Asp94Tyr,ciprofloxacin,Yes

gyrA,p.Asp94Val,ciprofloxacin,Yes

gyrA,p.Gly88Ala,ciprofloxacin,Yes

gyrA,p.Gly88Cys,ciprofloxacin,Yes

gyrA,p.His70Arg,ciprofloxacin,Yes

gyrA,p.Ile92Met,ciprofloxacin,No

gyrA,p.Leu109Val,ciprofloxacin,No

gyrA,p.Pro102His,ciprofloxacin,Yes

gyrA,p.Ser69Thr,ciprofloxacin,No

gyrA,p.Ser91Ala,ciprofloxacin,Yes

gyrA,p.Ser91Pro,ciprofloxacin,Yes

gyrB,p.Ala504Thr,ciprofloxacin,Yes

gyrB,p.Ala504Val,ciprofloxacin,Yes

gyrB,p.Ala90Gly,ciprofloxacin,No

gyrB,p.Arg446Cys,ciprofloxacin,Yes

gyrB,p.Arg446His,ciprofloxacin,Yes

gyrB,p.Arg446Leu,ciprofloxacin,No

gyrB,p.Asn499Asp,ciprofloxacin,Yes

gyrB,p.Asn499Lys,ciprofloxacin,Yes

gyrB,p.Asn499Thr,ciprofloxacin,Yes

gyrB,p.Asn499Tyr,ciprofloxacin,Yes

gyrB,p.Asp461Ala,ciprofloxacin,Yes

gyrB,p.Asp461Asn,ciprofloxacin,Yes

gyrB,p.Asp461His,ciprofloxacin,Yes

gyrB,p.Asp494Ala,ciprofloxacin,Yes

gyrB,p.Gln538His,ciprofloxacin,No

gyrB,p.Glu501Asp,ciprofloxacin,Yes

gyrB,p.Glu501Val,ciprofloxacin,Yes

gyrB,p.Gly470Ala,ciprofloxacin,No

gyrB,p.Gly470Cys,ciprofloxacin,No

gyrB,p.Ile486Leu,ciprofloxacin,Yes

gyrB,p.Ser447Phe,ciprofloxacin,Yes

gyrB,p.Thr500Asn,ciprofloxacin,Yes

gyrB,p.Thr500Ile,ciprofloxacin,Yes

gyrB,p.Thr500Pro,ciprofloxacin,Yes

gyrB,p.Thr507Met,ciprofloxacin,No

gyrB,p.Val670Phe,ciprofloxacin,Yes

Rv0678,c.192_193insG,clofazimine,No

Rv0678,c.38_39insA,clofazimine,No

Rv0678,p.Arg134*,clofazimine,No

Rv0678,p.Arg94Gln,clofazimine,No

Rv0678,p.Glu138Gly,clofazimine,No

Rv0678,p.Ser63Arg,clofazimine,No

Rv0678,p.Ser68Gly,clofazimine,No

ald,c.1106_1107insG,cycloserine,No

ald,c.128_129insG,cycloserine,No

ald,c.133_134insTC,cycloserine,No

ald,c.133del,cycloserine,No

ald,c.317_318insT,cycloserine,No

ald,c.433_434insGC,cycloserine,No

ald,c.460del,cycloserine,No

ald,c.837_838insCCGAC,cycloserine,No

ald,c.877_878insCG,cycloserine,No

ald,c.896_897insGA,cycloserine,No

ald,c.966_967insGA,cycloserine,No

ald,c.991_992insC,cycloserine,No

alr,p.Leu113Arg,cycloserine,Yes

alr,p.Met343Thr,cycloserine,Yes

alr,p.Phe4Leu,cycloserine,Yes

Rv3261,p.Asp49Tyr,delamanid,No

embA,c.-11C>A,ethambutol,Yes

embA,c.-12C>T,ethambutol,Yes

embA,c.-16C>G,ethambutol,Yes

embA,c.-16C>T,ethambutol,Yes

embA,c.-26del,ethambutol,No

embA,c.-28del,ethambutol,No

embA,c.-29_-28del,ethambutol,No

embA,c.-32del,ethambutol,No

embA,c.-34del,ethambutol,No

embA,c.-37del,ethambutol,No

embA,p.Ala462Val,ethambutol,No

embA,p.Asp4Asn,ethambutol,Yes

embA,p.Asp833Ala,ethambutol,No

embA,p.Gly321Ser,ethambutol,No

embA,p.Gly350Asp,ethambutol,No

embB,c.983del,ethambutol,No

embB,p.Ala221Gly,ethambutol,No

embB,p.Ala225Ser,ethambutol,No

embB,p.Ala271Val,ethambutol,No

embB,p.Ala281Pro,ethambutol,No

embB,p.Ala313Val,ethambutol,Yes

embB,p.Ala356Ser,ethambutol,No

embB,p.Ala356Val,ethambutol,Yes

embB,p.Ala357Ser,ethambutol,No

embB,p.Ala357Val,ethambutol,No

embB,p.Ala379Asp,ethambutol,No

embB,p.Ala379Thr,ethambutol,Yes

embB,p.Ala388Gly,ethambutol,Yes

embB,p.Ala431Thr,ethambutol,Yes

embB,p.Ala659Thr,ethambutol,Yes

embB,p.Arg257Trp,ethambutol,No

embB,p.Arg274Pro,ethambutol,No

embB,p.Arg367Pro,ethambutol,No

embB,p.Arg460Cys,ethambutol,No

embB,p.Arg460Leu,ethambutol,Yes

embB,p.Arg469Pro,ethambutol,No

embB,p.Arg471Pro,ethambutol,No

embB,p.Arg507Lys,ethambutol,No

embB,p.Asn296His,ethambutol,Yes

embB,p.Asn296Lys,ethambutol,No

embB,p.Asn318His,ethambutol,No

embB,p.Asn318Lys,ethambutol,No

embB,p.Asn318Ser,ethambutol,No

embB,p.Asn399Asp,ethambutol,Yes

embB,p.Asn399His,ethambutol,No

embB,p.Asn400Lys,ethambutol,No

embB,p.Asp1024Asn,ethambutol,Yes

embB,p.Asp240His,ethambutol,No

embB,p.Asp299Glu,ethambutol,No

embB,p.Asp311Gly,ethambutol,No

embB,p.Asp311His,ethambutol,No

embB,p.Asp328Gly,ethambutol,Yes

embB,p.Asp328Tyr,ethambutol,Yes

embB,p.Asp328Val,ethambutol,No

embB,p.Asp354Ala,ethambutol,Yes

embB,p.Asp959Ala,ethambutol,No

embB,p.Gln497Arg,ethambutol,Yes

embB,p.Gln497Lys,ethambutol,Yes

embB,p.Gln497Pro,ethambutol,Yes

embB,p.Gln853Pro,ethambutol,Yes

embB,p.Glu368Ala,ethambutol,No

embB,p.Glu368Asp,ethambutol,Yes

embB,p.Glu368Gln,ethambutol,No

embB,p.Glu378Lys,ethambutol,No

embB,p.Glu405Asp,ethambutol,Yes

embB,p.Glu504Asp,ethambutol,Yes

embB,p.Gly294Ser,ethambutol,No

embB,p.Gly314Ala,ethambutol,No

embB,p.Gly331Arg,ethambutol,No

embB,p.Gly358Val,ethambutol,No

embB,p.Gly374Val,ethambutol,No

embB,p.Gly401Ser,ethambutol,No

embB,p.Gly406Ala,ethambutol,Yes

embB,p.Gly406Asp,ethambutol,Yes

embB,p.Gly406Cys,ethambutol,Yes

embB,p.Gly406Ser,ethambutol,Yes

embB,p.Gly448Val,ethambutol,No

embB,p.Gly459Ala,ethambutol,No

embB,p.Gly745Asp,ethambutol,No

embB,p.His1002Arg,ethambutol,Yes

embB,p.His312Arg,ethambutol,Yes

embB,p.Ile293Asn,ethambutol,No

embB,p.Leu239Pro,ethambutol,No

embB,p.Leu359Ile,ethambutol,Yes

embB,p.Leu370Arg,ethambutol,Yes

embB,p.Met1000Arg,ethambutol,Yes

embB,p.Met306Ile,ethambutol,Yes

embB,p.Met306Leu,ethambutol,Yes

embB,p.Met306Thr,ethambutol,Yes

embB,p.Met306Val,ethambutol,Yes

embB,p.Met423Ile,ethambutol,Yes

embB,p.Met423Thr,ethambutol,Yes

embB,p.Met482Ile,ethambutol,No

embB,p.Phe285Leu,ethambutol,Yes

embB,p.Phe287Cys,ethambutol,No

embB,p.Phe287Val,ethambutol,No

embB,p.Phe320Leu,ethambutol,No

embB,p.Phe330Val,ethambutol,Yes

embB,p.Phe398Tyr,ethambutol,No

embB,p.Pro371Arg,ethambutol,Yes

embB,p.Pro375Ala,ethambutol,No

embB,p.Pro397Gln,ethambutol,Yes

embB,p.Pro397Thr,ethambutol,Yes

embB,p.Pro404Ser,ethambutol,Yes

embB,p.Pro430Leu,ethambutol,Yes

embB,p.Pro446His,ethambutol,No

embB,p.Pro461Ser,ethambutol,No

embB,p.Ser272Cys,ethambutol,No

embB,p.Ser272Ile,ethambutol,No

embB,p.Ser297Ala,ethambutol,Yes

embB,p.Ser297Leu,ethambutol,No

embB,p.Ser298Trp,ethambutol,No

embB,p.Ser317Thr,ethambutol,No

embB,p.Ser347Cys,ethambutol,No

embB,p.Ser347Ile,ethambutol,Yes

embB,p.Ser347Thr,ethambutol,Yes

embB,p.Ser366Pro,ethambutol,No

embB,p.Ser380Arg,ethambutol,No

embB,p.Ser380Asn,ethambutol,No

embB,p.Ser412Leu,ethambutol,No

embB,p.Thr437Ala,ethambutol,No

embB,p.Trp332Leu,ethambutol,No

embB,p.Trp395Arg,ethambutol,No

embB,p.Trp395Cys,ethambutol,No

embB,p.Tyr315Cys,ethambutol,No

embB,p.Tyr319Asn,ethambutol,No

embB,p.Tyr319Cys,ethambutol,Yes

embB,p.Tyr319Ser,ethambutol,Yes

embB,p.Tyr333His,ethambutol,No

embB,p.Tyr334His,ethambutol,Yes

embB,p.Tyr384Asn,ethambutol,Yes

embB,p.Val227Gly,ethambutol,No

embB,p.Val282Gly,ethambutol,No

embB,p.Val282Leu,ethambutol,No

embB,p.Val309Gly,ethambutol,No

embB,p.Val360Met,ethambutol,No

embB,p.Val369Ala,ethambutol,No

embB,p.Val369Leu,ethambutol,No

embB,p.Val377Gly,ethambutol,No

embB,p.Val377Met,ethambutol,No

embB,p.Val435Gly,ethambutol,No

embB,p.Val436Gly,ethambutol,No

embB,p.Val452Leu,ethambutol,Yes

embC,p.Ala244Thr,ethambutol,No

embC,p.Ala247Pro,ethambutol,No

embC,p.Ala254Gly,ethambutol,No

embC,p.Ala307Thr,ethambutol,Yes

embC,p.Ala779Val,ethambutol,Yes

embC,p.Arg302Gly,ethambutol,No

embC,p.Glu187Glu,ethambutol,No

embC,p.Gly272Ser,ethambutol,No

embC,p.Gly288Trp,ethambutol,Yes

embC,p.Gly288Val,ethambutol,No

embC,p.Gly308Asp,ethambutol,No

embC,p.Gly325Ser,ethambutol,No

embC,p.His285Tyr,ethambutol,No

embC,p.Ile297Leu,ethambutol,No

embC,p.Ile297Thr,ethambutol,No

embC,p.Leu251Arg,ethambutol,Yes

embC,p.Met300Arg,ethambutol,No

embC,p.Met310Lys,ethambutol,No

embC,p.Trp326Arg,ethambutol,No

embC,p.Tyr296His,ethambutol,No

embC,p.Tyr296Ser,ethambutol,No

embC,p.Tyr309Asn,ethambutol,No

embC,p.Tyr327Asn,ethambutol,No

embC,p.Val287Phe,ethambutol,No

embC,p.Val303Gly,ethambutol,No

embR,p.Ala176Val,ethambutol,No

embR,p.Ala187Val,ethambutol,No

embR,p.Arg186Gly,ethambutol,No

embR,p.Arg230Trp,ethambutol,No

embR,p.Arg356Gly,ethambutol,No

embR,p.Asp223Glu,ethambutol,No

embR,p.Asp53His,ethambutol,No

embR,p.Gln379Arg,ethambutol,Yes

embR,p.Glu200Ala,ethambutol,No

embR,p.Gly240Arg,ethambutol,No

embR,p.Ile369Thr,ethambutol,No

embR,p.Leu172Arg,ethambutol,Yes

embR,p.Leu211Met,ethambutol,No

embR,p.Leu292Met,ethambutol,No

embR,p.Leu320Val,ethambutol,No

embR,p.Ser188Arg,ethambutol,No

embR,p.Ser326Asn,ethambutol,No

embR,p.Thr32Pro,ethambutol,No

embR,p.Val350Gly,ethambutol,No

embR,p.Val7Gly,ethambutol,Yes

ethA,c.101del,ethionamide,No

ethA,c.1023_1024insGC,ethionamide,No

ethA,c.1047del,ethionamide,No

ethA,c.1054del,ethionamide,No

ethA,c.1057_1059del,ethionamide,Yes

ethA,c.1080del,ethionamide,No

ethA,c.1104del,ethionamide,No

ethA,c.110del,ethionamide,No

ethA,c.1164_1165insA,ethionamide,No

ethA,c.119_120insA,ethionamide,No

ethA,c.1194_1195insT,ethionamide,No

ethA,c.1195_1196insGTG,ethionamide,No

ethA,c.-11A>G,ethionamide,Yes

ethA,c.1215_1224del,ethionamide,Yes

ethA,c.1242del,ethionamide,No

ethA,c.1290del,ethionamide,No

ethA,c.1304_1305insA,ethionamide,No

ethA,c.130del,ethionamide,No

ethA,c.1322_1323del,ethionamide,No

ethA,c.1406_1407insC,ethionamide,No

ethA,c.140del,ethionamide,No

ethA,c.1465del,ethionamide,No

ethA,c.180del,ethionamide,No

ethA,c.229del,ethionamide,No

ethA,c.308del,ethionamide,No

ethA,c.492_493insCC,ethionamide,No

ethA,c.597del,ethionamide,No

ethA,c.621_622insG,ethionamide,No

ethA,c.639_640del,ethionamide,Yes

ethA,c.673_674insG,ethionamide,No

ethA,c.674_675insGC,ethionamide,No

ethA,c.701_702insGG,ethionamide,No

ethA,c.703del,ethionamide,No

ethA,c.753_754insG,ethionamide,No

ethA,c.756_757insGC,ethionamide,No

ethA,c.768del,ethionamide,No

ethA,c.771_772insC,ethionamide,No

ethA,c.774del,ethionamide,No

ethA,c.785_787del,ethionamide,Yes

ethA,c.852_853insC,ethionamide,No

ethA,c.870_871insA,ethionamide,No

ethA,c.884del,ethionamide,No

ethA,c.896del,ethionamide,No

ethA,frameshift,ethionamide,No

ethA,large_deletion,ethionamide,No

ethA,p.Ala381Pro,ethionamide,Yes

ethA,p.Arg463Ser,ethionamide,No

ethA,p.Asp58Ala,ethionamide,Yes

ethA,p.Cys403Gly,ethionamide,No

ethA,p.Gln165Pro,ethionamide,Yes

ethA,p.Gln246*,ethionamide,No

ethA,p.Gln269*,ethionamide,No

ethA,p.Gln347*,ethionamide,No

ethA,p.Glu223Lys,ethionamide,Yes

ethA,p.Gly11Ala,ethionamide,No

ethA,p.Gly385Asp,ethionamide,Yes

ethA,p.Gly413Asp,ethionamide,Yes

ethA,p.Gly43Cys,ethionamide,Yes

ethA,p.Gly43Ser,ethionamide,Yes

ethA,p.His22Pro,ethionamide,Yes

ethA,p.Ile338Ser,ethionamide,Yes

ethA,p.Leu272Pro,ethionamide,Yes

ethA,p.Leu333Arg,ethionamide,No

ethA,p.Leu397Arg,ethionamide,Yes

ethA,p.Met1Arg,ethionamide,Yes

ethA,p.Pro51Leu,ethionamide,Yes

ethA,p.Ser329Leu,ethionamide,No

ethA,p.Thr186Lys,ethionamide,No

ethA,p.Thr232Ala,ethionamide,Yes

ethA,p.Thr342Lys,ethionamide,Yes

ethA,p.Thr392Ala,ethionamide,Yes

ethA,p.Thr61Met,ethionamide,Yes

ethA,p.Tyr386Cys,ethionamide,Yes

ethA,p.Tyr461His,ethionamide,No

ethA,p.Tyr84Asp,ethionamide,Yes

ethR,p.Ala95Thr,ethionamide,Yes

ethR,p.Phe110Leu,ethionamide,Yes

fabG1,c.-15C>T,ethionamide,Yes

fabG1,c.-17G>T,ethionamide,Yes

fabG1,c.-8T>C,ethionamide,Yes

inhA,p.Ile194Thr,ethionamide,Yes

inhA,p.Ile21Thr,ethionamide,Yes

inhA,p.Ser94Ala,ethionamide,Yes

gyrA,p.Ala74Ser,fluoroquinolones,Yes

gyrA,p.Ala90Glu,fluoroquinolones,Yes

gyrA,p.Ala90Gly,fluoroquinolones,Yes

gyrA,p.Ala90Val,fluoroquinolones,Yes

gyrA,p.Arg68Gly,fluoroquinolones,No

gyrA,p.Asp89Asn,fluoroquinolones,Yes

gyrA,p.Asp94Ala,fluoroquinolones,Yes

gyrA,p.Asp94Asn,fluoroquinolones,Yes

gyrA,p.Asp94Gly,fluoroquinolones,Yes

gyrA,p.Asp94His,fluoroquinolones,Yes

gyrA,p.Asp94Tyr,fluoroquinolones,Yes

gyrA,p.Asp94Val,fluoroquinolones,Yes

gyrA,p.Gly88Ala,fluoroquinolones,Yes

gyrA,p.Gly88Cys,fluoroquinolones,Yes

gyrA,p.His70Arg,fluoroquinolones,Yes

gyrA,p.Ile92Met,fluoroquinolones,No

gyrA,p.Leu109Val,fluoroquinolones,No

gyrA,p.Pro102His,fluoroquinolones,Yes

gyrA,p.Ser69Thr,fluoroquinolones,No

gyrA,p.Ser91Ala,fluoroquinolones,Yes

gyrA,p.Ser91Pro,fluoroquinolones,Yes

gyrB,p.Ala504Thr,fluoroquinolones,Yes

gyrB,p.Ala504Val,fluoroquinolones,Yes

gyrB,p.Ala90Gly,fluoroquinolones,No

gyrB,p.Arg446Cys,fluoroquinolones,Yes

gyrB,p.Arg446His,fluoroquinolones,Yes

gyrB,p.Arg446Leu,fluoroquinolones,No

gyrB,p.Asn499Asp,fluoroquinolones,Yes

gyrB,p.Asn499Lys,fluoroquinolones,Yes

gyrB,p.Asn499Thr,fluoroquinolones,Yes

gyrB,p.Asn499Tyr,fluoroquinolones,Yes

gyrB,p.Asp461Ala,fluoroquinolones,Yes

gyrB,p.Asp461Asn,fluoroquinolones,Yes

gyrB,p.Asp461His,fluoroquinolones,Yes

gyrB,p.Asp494Ala,fluoroquinolones,Yes

gyrB,p.Gln538His,fluoroquinolones,No

gyrB,p.Glu501Asp,fluoroquinolones,Yes

gyrB,p.Glu501Val,fluoroquinolones,Yes

gyrB,p.Gly470Ala,fluoroquinolones,No

gyrB,p.Gly470Cys,fluoroquinolones,No

gyrB,p.Ile486Leu,fluoroquinolones,Yes

gyrB,p.Ser447Phe,fluoroquinolones,Yes

gyrB,p.Thr500Asn,fluoroquinolones,Yes

gyrB,p.Thr500Ile,fluoroquinolones,Yes

gyrB,p.Thr500Pro,fluoroquinolones,Yes

gyrB,p.Thr507Met,fluoroquinolones,No

gyrB,p.Val670Phe,fluoroquinolones,Yes

ahpC,c.-20C>T,isoniazid,No

ahpC,c.-39C>T,isoniazid,Yes

ahpC,c.-44T>A,isoniazid,No

ahpC,c.-48G>A,isoniazid,Yes

ahpC,c.-48G>T,isoniazid,No

ahpC,c.-49T>G,isoniazid,No

ahpC,c.-4A>G,isoniazid,No

ahpC,c.-51G>T,isoniazid,No

ahpC,c.-52C>T,isoniazid,Yes

ahpC,c.-54C>T,isoniazid,Yes

ahpC,c.-5G>A,isoniazid,No

ahpC,c.-66G>A,isoniazid,No

ahpC,c.-74G>A,isoniazid,Yes

ahpC,c.-81C>T,isoniazid,Yes

ahpC,p.Asp33Asn,isoniazid,No

ahpC,p.Asp73His,isoniazid,Yes

ahpC,p.Glu76Lys,isoniazid,Yes

ahpC,p.Leu191Arg,isoniazid,Yes

ahpC,p.Phe10Ile,isoniazid,No

ahpC,p.Pro2Ser,isoniazid,Yes

ahpC,p.Thr5Ile,isoniazid,No

fabG1,c.-11A>T,isoniazid,No

fabG1,c.-15C>T,isoniazid,Yes

fabG1,c.-16A>G,isoniazid,No

fabG1,c.-17G>T,isoniazid,Yes

fabG1,c.-24G>T,isoniazid,No

fabG1,c.-5T>A,isoniazid,No

fabG1,c.-67G>C,isoniazid,No

fabG1,c.-8T>A,isoniazid,Yes

fabG1,c.-8T>C,isoniazid,Yes

fabG1,c.-8T>G,isoniazid,Yes

fabG1,c.-92A>T,isoniazid,No

inhA,p.Gly40Trp,isoniazid,Yes

inhA,p.Ile16Thr,isoniazid,Yes

inhA,p.Ile194Thr,isoniazid,Yes

inhA,p.Ile21Asn,isoniazid,No

inhA,p.Ile21Thr,isoniazid,Yes

inhA,p.Ile21Val,isoniazid,Yes

inhA,p.Ile47Thr,isoniazid,No

inhA,p.Ile95Thr,isoniazid,No

inhA,p.Leu11Val,isoniazid,No

inhA,p.Lys8Asn,isoniazid,No

inhA,p.Ser94Ala,isoniazid,Yes

inhA,p.Ser94Leu,isoniazid,No

inhA,p.Ser94Trp,isoniazid,No

kasA,p.Arg121Lys,isoniazid,No

kasA,p.Asp66Asn,isoniazid,No

kasA,p.Gly387Asp,isoniazid,Yes

kasA,p.Met77Ile,isoniazid,No

katG,c.1037del,isoniazid,No

katG,c.1091del,isoniazid,No

katG,c.109del,isoniazid,No

katG,c.-10A>C,isoniazid,Yes

katG,c.1171_1172insCTA,isoniazid,No

katG,c.1203del,isoniazid,No

katG,c.-12G>A,isoniazid,No

katG,c.1330_1331insA,isoniazid,No

katG,c.1339_1350del,isoniazid,Yes

katG,c.149del,isoniazid,No

katG,c.152_166del,isoniazid,No

katG,c.1560_1561insTGCAGCCACAAGTCGGGTGGGAGGTCAACGACCCCGACGGGGATCTGCGCAAGGTCATTCGCAC,isoniazid,No

katG,c.1612_1613insA,isoniazid,No

katG,c.1667del,isoniazid,No

katG,c.1804_1810del,isoniazid,Yes

katG,c.1850_1851insAC,isoniazid,No

katG,c.186_187insC,isoniazid,No

katG,c.1901_1902insC,isoniazid,No

katG,c.196_197insCCCC,isoniazid,No

katG,c.2203_2205del,isoniazid,No

katG,c.269_270insT,isoniazid,No

katG,c.28_35del,isoniazid,No

katG,c.317_318insG,isoniazid,No

katG,c.358_369del,isoniazid,No

katG,c.372_373del,isoniazid,Yes

katG,c.373_374insG,isoniazid,No

katG,c.374_375insCAT,isoniazid,No

katG,c.54del,isoniazid,No

katG,c.561del,isoniazid,No

katG,c.572del,isoniazid,No

katG,c.6_7del,isoniazid,No

katG,c.795del,isoniazid,No

katG,c.-7G>A,isoniazid,No

katG,c.803del,isoniazid,No

katG,c.861_866del,isoniazid,Yes

katG,c.86_88del,isoniazid,Yes

katG,c.902_903insT,isoniazid,No

katG,c.928del,isoniazid,No

katG,c.956del,isoniazid,No

katG,c.99_100insA,isoniazid,No

katG,frameshift,isoniazid,No

katG,large_deletion,isoniazid,No

katG,p.Ala106Val,isoniazid,Yes

katG,p.Ala109Val,isoniazid,Yes

katG,p.Ala110Val,isoniazid,Yes

katG,p.Ala139Pro,isoniazid,Yes

katG,p.Ala162Thr,isoniazid,No

katG,p.Ala172Thr,isoniazid,No

katG,p.Ala172Val,isoniazid,Yes

katG,p.Ala243Ser,isoniazid,No

katG,p.Ala264Thr,isoniazid,Yes

katG,p.Ala281Val,isoniazid,No

katG,p.Ala291Pro,isoniazid,No

katG,p.Ala350Ser,isoniazid,No

katG,p.Ala350Thr,isoniazid,No

katG,p.Ala361Asp,isoniazid,No

katG,p.Ala379Val,isoniazid,Yes

katG,p.Ala409Asp,isoniazid,No

katG,p.Ala424Glu,isoniazid,No

katG,p.Ala424Gly,isoniazid,Yes

katG,p.Ala424Val,isoniazid,No

katG,p.Ala444Thr,isoniazid,No

katG,p.Ala464Ser,isoniazid,No

katG,p.Ala550Asp,isoniazid,Yes

katG,p.Ala551Gly,isoniazid,No

katG,p.Ala574Glu,isoniazid,No

katG,p.Ala574Val,isoniazid,No

katG,p.Ala61Thr,isoniazid,No

katG,p.Ala636Glu,isoniazid,No

katG,p.Ala65Thr,isoniazid,Yes

katG,p.Ala66Pro,isoniazid,No

katG,p.Ala713Pro,isoniazid,No

katG,p.Ala716Pro,isoniazid,No

katG,p.Ala727Asp,isoniazid,No

katG,p.Arg104Gln,isoniazid,Yes

katG,p.Arg104Leu,isoniazid,No

katG,p.Arg128Pro,isoniazid,No

katG,p.Arg249Cys,isoniazid,Yes

katG,p.Arg418Gln,isoniazid,No

katG,p.Arg418Leu,isoniazid,No

katG,p.Arg463Trp,isoniazid,No

katG,p.Arg484Ser,isoniazid,Yes

katG,p.Arg496Leu,isoniazid,Yes

katG,p.Arg515Cys,isoniazid,No

katG,p.Asn138Asp,isoniazid,Yes

katG,p.Asn138His,isoniazid,Yes

katG,p.Asn138Ser,isoniazid,Yes

katG,p.Asn138Thr,isoniazid,No

katG,p.Asn218Lys,isoniazid,No

katG,p.Asn236Thr,isoniazid,No

katG,p.Asn238Lys,isoniazid,No

katG,p.Asn258Ser,isoniazid,No

katG,p.Asn35Asp,isoniazid,No

katG,p.Asn529Asp,isoniazid,No

katG,p.Asp117Ala,isoniazid,Yes

katG,p.Asp142Ala,isoniazid,No

katG,p.Asp259Glu,isoniazid,Yes

katG,p.Asp311Glu,isoniazid,No

katG,p.Asp311Gly,isoniazid,No

katG,p.Asp311Tyr,isoniazid,No

katG,p.Asp357Asn,isoniazid,No

katG,p.Asp357His,isoniazid,No

katG,p.Asp381Gly,isoniazid,No

katG,p.Asp419His,isoniazid,Yes

katG,p.Asp573Asn,isoniazid,No

katG,p.Asp63Glu,isoniazid,No

katG,p.Asp695Ala,isoniazid,Yes

katG,p.Asp72Gly,isoniazid,No

katG,p.Asp735Ala,isoniazid,No

katG,p.Asp735Asn,isoniazid,No

katG,p.Asp74Gly,isoniazid,No

katG,p.Asp74Tyr,isoniazid,No

katG,p.Asp94Ala,isoniazid,No

katG,p.Asp94Gly,isoniazid,No

katG,p.Gln127Pro,isoniazid,Yes

katG,p.Gln224Glu,isoniazid,No

katG,p.Gln295Pro,isoniazid,Yes

katG,p.Gln352*,isoniazid,No

katG,p.Gln434*,isoniazid,No

katG,p.Gln461Pro,isoniazid,Yes

katG,p.Gln502His,isoniazid,No

katG,p.Gln525Pro,isoniazid,Yes

katG,p.Gln717Pro,isoniazid,No

katG,p.Gln88Arg,isoniazid,No

katG,p.Glu195Lys,isoniazid,Yes

katG,p.Glu261Lys,isoniazid,No

katG,p.Glu289Asp,isoniazid,No

katG,p.Glu607Lys,isoniazid,No

katG,p.Gly121Cys,isoniazid,No

katG,p.Gly121Val,isoniazid,No

katG,p.Gly125Cys,isoniazid,No

katG,p.Gly169Ala,isoniazid,No

katG,p.Gly186Val,isoniazid,No

katG,p.Gly19Asp,isoniazid,No

katG,p.Gly234Arg,isoniazid,No

katG,p.Gly234Glu,isoniazid,No

katG,p.Gly279Asp,isoniazid,Yes

katG,p.Gly285Asp,isoniazid,Yes

katG,p.Gly297Val,isoniazid,Yes

katG,p.Gly299Ala,isoniazid,No

katG,p.Gly299Cys,isoniazid,No

katG,p.Gly305Ala,isoniazid,No

katG,p.Gly307Ala,isoniazid,No

katG,p.Gly307Arg,isoniazid,No

katG,p.Gly307Glu,isoniazid,No

katG,p.Gly309Asp,isoniazid,No

katG,p.Gly309Cys,isoniazid,No

katG,p.Gly309Ser,isoniazid,No

katG,p.Gly316Asp,isoniazid,No

katG,p.Gly316Ser,isoniazid,No

katG,p.Gly428Arg,isoniazid,No

katG,p.Gly485Val,isoniazid,No

katG,p.Gly491Cys,isoniazid,No

katG,p.Gly593Asp,isoniazid,No

katG,p.Gly629Ser,isoniazid,No

katG,p.Gly685Arg,isoniazid,No

katG,p.Gly96Cys,isoniazid,No

katG,p.Gly99Glu,isoniazid,Yes

katG,p.His108Asp,isoniazid,No

katG,p.His108Gln,isoniazid,No

katG,p.Ile317Leu,isoniazid,Yes

katG,p.Ile317Val,isoniazid,Yes

katG,p.Ile335Thr,isoniazid,Yes

katG,p.Ile335Val,isoniazid,Yes

katG,p.Ile393Asn,isoniazid,Yes

katG,p.Ile462Thr,isoniazid,No

katG,p.Ile71Asn,isoniazid,No

katG,p.Leu141Phe,isoniazid,Yes

katG,p.Leu148Arg,isoniazid,No

katG,p.Leu336Arg,isoniazid,No

katG,p.Leu378Pro,isoniazid,Yes

katG,p.Leu384Arg,isoniazid,Yes

katG,p.Leu449Phe,isoniazid,No

katG,p.Leu48Gln,isoniazid,No

katG,p.Leu587Met,isoniazid,No

katG,p.Leu587Pro,isoniazid,Yes

katG,p.Leu619Pro,isoniazid,No

katG,p.Leu634Phe,isoniazid,No

katG,p.Leu653Pro,isoniazid,No

katG,p.Lys143Thr,isoniazid,No

katG,p.Lys200*,isoniazid,No

katG,p.Lys345Thr,isoniazid,No

katG,p.Lys414Asn,isoniazid,No

katG,p.Lys459*,isoniazid,No

katG,p.Lys488Asn,isoniazid,No

katG,p.Met126Ile,isoniazid,Yes

katG,p.Met176Ile,isoniazid,No

katG,p.Met257Ile,isoniazid,Yes

katG,p.Met257Thr,isoniazid,No

katG,p.Met609Ile,isoniazid,No

katG,p.Met84Ile,isoniazid,Yes

katG,p.Phe252Leu,isoniazid,No

katG,p.Phe567Ser,isoniazid,Yes

katG,p.Pro241Pro,isoniazid,No

katG,p.Pro2Ser,isoniazid,No

katG,p.Pro365Leu,isoniazid,No

katG,p.Pro429Ser,isoniazid,No

katG,p.Pro589Thr,isoniazid,No

katG,p.Ser140Arg,isoniazid,Yes

katG,p.Ser140Asn,isoniazid,Yes

katG,p.Ser140Gly,isoniazid,Yes

katG,p.Ser160Leu,isoniazid,No

katG,p.Ser17Asn,isoniazid,Yes

katG,p.Ser302Arg,isoniazid,Yes

katG,p.Ser315Arg,isoniazid,Yes

katG,p.Ser315Asn,isoniazid,Yes

katG,p.Ser315Gly,isoniazid,Yes

katG,p.Ser315Ile,isoniazid,Yes

katG,p.Ser315Thr,isoniazid,Yes

katG,p.Ser331Cys,isoniazid,No

katG,p.Ser457Ile,isoniazid,No

katG,p.Ser700Pro,isoniazid,Yes

katG,p.Thr11Ala,isoniazid,No

katG,p.Thr12Pro,isoniazid,No

katG,p.Thr180Lys,isoniazid,Yes

katG,p.Thr251Met,isoniazid,No

katG,p.Thr262Arg,isoniazid,No

katG,p.Thr275Ala,isoniazid,Yes

katG,p.Thr275Pro,isoniazid,No

katG,p.Thr275Ser,isoniazid,No

katG,p.Thr308Pro,isoniazid,No

katG,p.Thr324Pro,isoniazid,No

katG,p.Thr326Met,isoniazid,Yes

katG,p.Thr380Ile,isoniazid,Yes

katG,p.Thr394Ala,isoniazid,Yes

katG,p.Thr435Ile,isoniazid,No

katG,p.Thr85Pro,isoniazid,No

katG,p.Trp107Arg,isoniazid,No

katG,p.Trp107*,isoniazid,No

katG,p.Trp191Arg,isoniazid,Yes

katG,p.Trp198*,isoniazid,No

katG,p.Trp300Gly,isoniazid,No

katG,p.Trp300*,isoniazid,No

katG,p.Trp321Arg,isoniazid,No

katG,p.Trp321Cys,isoniazid,No

katG,p.Trp321*,isoniazid,No

katG,p.Trp321Leu,isoniazid,No

katG,p.Trp321Ser,isoniazid,No

katG,p.Trp328Cys,isoniazid,No

katG,p.Trp328Gly,isoniazid,No

katG,p.Trp328Leu,isoniazid,Yes

katG,p.Trp328Ser,isoniazid,Yes

katG,p.Trp341Ser,isoniazid,No

katG,p.Trp38*,isoniazid,No

katG,p.Trp397*,isoniazid,No

katG,p.Trp477*,isoniazid,No

katG,p.Trp505Arg,isoniazid,No

katG,p.Trp505Ser,isoniazid,No

katG,p.Trp728Cys,isoniazid,Yes

katG,p.Trp90*,isoniazid,No

katG,p.Trp91Arg,isoniazid,Yes

katG,p.Tyr155Cys,isoniazid,Yes

katG,p.Tyr155Ser,isoniazid,Yes

katG,p.Tyr229Phe,isoniazid,No

katG,p.Tyr304Ser,isoniazid,No

katG,p.Tyr337Cys,isoniazid,Yes

katG,p.Tyr337Phe,isoniazid,No

katG,p.Tyr413His,isoniazid,Yes

katG,p.Val1Ala,isoniazid,Yes

katG,p.Val1Leu,isoniazid,Yes

katG,p.Val230Ala,isoniazid,No

katG,p.Val473Phe,isoniazid,Yes

katG,p.Val710Ala,isoniazid,No

eis,c.-10G>A,kanamycin,Yes

eis,c.-10G>C,kanamycin,Yes

eis,c.-12C>T,kanamycin,Yes

eis,c.-13A>G,kanamycin,Yes

eis,c.-14C>T,kanamycin,Yes

eis,c.-15C>G,kanamycin,Yes

eis,c.-37G>T,kanamycin,Yes

eis,c.-53T>G,kanamycin,No

eis,c.-54G>T,kanamycin,No

eis,c.-8C>A,kanamycin,Yes

rrs,r.1401a>g,kanamycin,Yes

rrs,r.1402c>a,kanamycin,Yes

rrs,r.1402c>t,kanamycin,Yes

rrs,r.1484g>t,kanamycin,Yes

gyrA,p.Ala74Ser,levofloxacin,Yes

gyrA,p.Ala90Glu,levofloxacin,Yes

gyrA,p.Ala90Gly,levofloxacin,Yes

gyrA,p.Ala90Val,levofloxacin,Yes

gyrA,p.Arg68Gly,levofloxacin,No

gyrA,p.Asp89Asn,levofloxacin,Yes

gyrA,p.Asp94Ala,levofloxacin,Yes

gyrA,p.Asp94Asn,levofloxacin,Yes

gyrA,p.Asp94Gly,levofloxacin,Yes

gyrA,p.Asp94His,levofloxacin,Yes

gyrA,p.Asp94Tyr,levofloxacin,Yes

gyrA,p.Asp94Val,levofloxacin,Yes

gyrA,p.Gly88Ala,levofloxacin,Yes

gyrA,p.Gly88Cys,levofloxacin,Yes

gyrA,p.His70Arg,levofloxacin,Yes

gyrA,p.Ile92Met,levofloxacin,No

gyrA,p.Leu109Val,levofloxacin,No

gyrA,p.Pro102His,levofloxacin,Yes

gyrA,p.Ser69Thr,levofloxacin,No

gyrA,p.Ser91Ala,levofloxacin,Yes

gyrA,p.Ser91Pro,levofloxacin,Yes

gyrB,p.Ala504Thr,levofloxacin,Yes

gyrB,p.Ala504Val,levofloxacin,Yes

gyrB,p.Ala90Gly,levofloxacin,No

gyrB,p.Arg446Cys,levofloxacin,Yes

gyrB,p.Arg446His,levofloxacin,Yes

gyrB,p.Arg446Leu,levofloxacin,No

gyrB,p.Asn499Asp,levofloxacin,Yes

gyrB,p.Asn499Lys,levofloxacin,Yes

gyrB,p.Asn499Thr,levofloxacin,Yes

gyrB,p.Asn499Tyr,levofloxacin,Yes

gyrB,p.Asp461Ala,levofloxacin,Yes

gyrB,p.Asp461Asn,levofloxacin,Yes

gyrB,p.Asp461His,levofloxacin,Yes

gyrB,p.Asp494Ala,levofloxacin,Yes

gyrB,p.Gln538His,levofloxacin,No

gyrB,p.Glu501Asp,levofloxacin,Yes

gyrB,p.Glu501Val,levofloxacin,Yes

gyrB,p.Gly470Ala,levofloxacin,No

gyrB,p.Gly470Cys,levofloxacin,No

gyrB,p.Ile486Leu,levofloxacin,Yes

gyrB,p.Ser447Phe,levofloxacin,Yes

gyrB,p.Thr500Asn,levofloxacin,Yes

gyrB,p.Thr500Ile,levofloxacin,Yes

gyrB,p.Thr500Pro,levofloxacin,Yes

gyrB,p.Thr507Met,levofloxacin,No

gyrB,p.Val670Phe,levofloxacin,Yes

rplC,p.Cys154Arg,linezolid,Yes

rrl,r.2299g>t,linezolid,No

rrl,r.2814g>t,linezolid,Yes

gyrA,p.Ala74Ser,moxifloxacin,Yes

gyrA,p.Ala90Glu,moxifloxacin,Yes

gyrA,p.Ala90Gly,moxifloxacin,Yes

gyrA,p.Ala90Val,moxifloxacin,Yes

gyrA,p.Arg68Gly,moxifloxacin,No

gyrA,p.Asp89Asn,moxifloxacin,Yes

gyrA,p.Asp94Ala,moxifloxacin,Yes

gyrA,p.Asp94Asn,moxifloxacin,Yes

gyrA,p.Asp94Gly,moxifloxacin,Yes

gyrA,p.Asp94His,moxifloxacin,Yes

gyrA,p.Asp94Tyr,moxifloxacin,Yes

gyrA,p.Asp94Val,moxifloxacin,Yes

gyrA,p.Gly88Ala,moxifloxacin,Yes

gyrA,p.Gly88Cys,moxifloxacin,Yes

gyrA,p.His70Arg,moxifloxacin,Yes

gyrA,p.Ile92Met,moxifloxacin,No

gyrA,p.Leu109Val,moxifloxacin,No

gyrA,p.Pro102His,moxifloxacin,Yes

gyrA,p.Ser69Thr,moxifloxacin,No

gyrA,p.Ser91Ala,moxifloxacin,Yes

gyrA,p.Ser91Pro,moxifloxacin,Yes

gyrB,p.Ala504Thr,moxifloxacin,Yes

gyrB,p.Ala504Val,moxifloxacin,Yes

gyrB,p.Ala90Gly,moxifloxacin,No

gyrB,p.Arg446Cys,moxifloxacin,Yes

gyrB,p.Arg446His,moxifloxacin,Yes

gyrB,p.Arg446Leu,moxifloxacin,No

gyrB,p.Asn499Asp,moxifloxacin,Yes

gyrB,p.Asn499Lys,moxifloxacin,Yes

gyrB,p.Asn499Thr,moxifloxacin,Yes

gyrB,p.Asn499Tyr,moxifloxacin,Yes

gyrB,p.Asp461Ala,moxifloxacin,Yes

gyrB,p.Asp461Asn,moxifloxacin,Yes

gyrB,p.Asp461His,moxifloxacin,Yes

gyrB,p.Asp494Ala,moxifloxacin,Yes

gyrB,p.Gln538His,moxifloxacin,No

gyrB,p.Glu501Asp,moxifloxacin,Yes

gyrB,p.Glu501Val,moxifloxacin,Yes

gyrB,p.Gly470Ala,moxifloxacin,No

gyrB,p.Gly470Cys,moxifloxacin,No

gyrB,p.Ile486Leu,moxifloxacin,Yes

gyrB,p.Ser447Phe,moxifloxacin,Yes

gyrB,p.Thr500Asn,moxifloxacin,Yes

gyrB,p.Thr500Ile,moxifloxacin,Yes

gyrB,p.Thr500Pro,moxifloxacin,Yes

gyrB,p.Thr507Met,moxifloxacin,No

gyrB,p.Val670Phe,moxifloxacin,Yes

gyrA,p.Ala74Ser,ofloxacin,Yes

gyrA,p.Ala90Glu,ofloxacin,Yes

gyrA,p.Ala90Gly,ofloxacin,Yes

gyrA,p.Ala90Val,ofloxacin,Yes

gyrA,p.Arg68Gly,ofloxacin,No

gyrA,p.Asp89Asn,ofloxacin,Yes

gyrA,p.Asp94Ala,ofloxacin,Yes

gyrA,p.Asp94Asn,ofloxacin,Yes

gyrA,p.Asp94Gly,ofloxacin,Yes

gyrA,p.Asp94His,ofloxacin,Yes

gyrA,p.Asp94Tyr,ofloxacin,Yes

gyrA,p.Asp94Val,ofloxacin,Yes

gyrA,p.Gly88Ala,ofloxacin,Yes

gyrA,p.Gly88Cys,ofloxacin,Yes

gyrA,p.His70Arg,ofloxacin,Yes

gyrA,p.Ile92Met,ofloxacin,No

gyrA,p.Leu109Val,ofloxacin,No

gyrA,p.Pro102His,ofloxacin,Yes

gyrA,p.Ser69Thr,ofloxacin,No

gyrA,p.Ser91Ala,ofloxacin,Yes

gyrA,p.Ser91Pro,ofloxacin,Yes

gyrB,p.Ala504Thr,ofloxacin,Yes

gyrB,p.Ala504Val,ofloxacin,Yes

gyrB,p.Ala90Gly,ofloxacin,No

gyrB,p.Arg446Cys,ofloxacin,Yes

gyrB,p.Arg446His,ofloxacin,Yes

gyrB,p.Arg446Leu,ofloxacin,No

gyrB,p.Asn499Asp,ofloxacin,Yes

gyrB,p.Asn499Lys,ofloxacin,Yes

gyrB,p.Asn499Thr,ofloxacin,Yes

gyrB,p.Asn499Tyr,ofloxacin,Yes

gyrB,p.Asp461Ala,ofloxacin,Yes

gyrB,p.Asp461Asn,ofloxacin,Yes

gyrB,p.Asp461His,ofloxacin,Yes

gyrB,p.Asp494Ala,ofloxacin,Yes

gyrB,p.Gln538His,ofloxacin,No

gyrB,p.Glu501Asp,ofloxacin,Yes

gyrB,p.Glu501Val,ofloxacin,Yes

gyrB,p.Gly470Ala,ofloxacin,No

gyrB,p.Gly470Cys,ofloxacin,No

gyrB,p.Ile486Leu,ofloxacin,Yes

gyrB,p.Ser447Phe,ofloxacin,Yes

gyrB,p.Thr500Asn,ofloxacin,Yes

gyrB,p.Thr500Ile,ofloxacin,Yes

gyrB,p.Thr500Pro,ofloxacin,Yes

gyrB,p.Thr507Met,ofloxacin,No

gyrB,p.Val670Phe,ofloxacin,Yes

folC,p.Ala183Pro,para-aminosalicylic_acid,No

folC,p.Arg49Pro,para-aminosalicylic_acid,Yes

folC,p.Arg49Trp,para-aminosalicylic_acid,Yes

folC,p.Arg91Trp,para-aminosalicylic_acid,No

folC,p.Asn73Ser,para-aminosalicylic_acid,No

folC,p.Glu153Ala,para-aminosalicylic_acid,Yes

folC,p.Glu153Gly,para-aminosalicylic_acid,Yes

folC,p.Glu40Gln,para-aminosalicylic_acid,Yes

folC,p.Glu40Gly,para-aminosalicylic_acid,Yes

folC,p.Ile43Ser,para-aminosalicylic_acid,Yes

folC,p.Ile43Thr,para-aminosalicylic_acid,Yes

folC,p.Leu56Val,para-aminosalicylic_acid,No

folC,p.Phe152Leu,para-aminosalicylic_acid,No

folC,p.Phe152Ser,para-aminosalicylic_acid,No

folC,p.Ser150Arg,para-aminosalicylic_acid,No

folC,p.Ser150Cys,para-aminosalicylic_acid,No

folC,p.Ser150Gly,para-aminosalicylic_acid,Yes

folC,p.Thr20Pro,para-aminosalicylic_acid,Yes

ribD,p.Gly8Arg,para-aminosalicylic_acid,Yes

thyA,c.111del,para-aminosalicylic_acid,No

thyA,c.218_219insCACGAGCAC,para-aminosalicylic_acid,No

thyA,c.260del,para-aminosalicylic_acid,No

thyA,c.373_374insT,para-aminosalicylic_acid,No

thyA,c.472del,para-aminosalicylic_acid,No

thyA,large_deletion,para-aminosalicylic_acid,No

thyA,p.Arg126Gln,para-aminosalicylic_acid,No

thyA,p.Arg222Gly,para-aminosalicylic_acid,Yes

thyA,p.Arg235Pro,para-aminosalicylic_acid,Yes

thyA,p.Cys161Tyr,para-aminosalicylic_acid,No

thyA,p.Gly76*,para-aminosalicylic_acid,No

thyA,p.Gly91Arg,para-aminosalicylic_acid,No

thyA,p.His207Arg,para-aminosalicylic_acid,Yes

thyA,p.His75Asn,para-aminosalicylic_acid,Yes

thyA,p.Phe152Val,para-aminosalicylic_acid,Yes

thyA,p.Pro224Leu,para-aminosalicylic_acid,No

thyA,p.Ser105Pro,para-aminosalicylic_acid,No

thyA,p.Thr22Ala,para-aminosalicylic_acid,Yes

thyA,p.Trp101Arg,para-aminosalicylic_acid,No

thyA,p.Trp83Cys,para-aminosalicylic_acid,No

thyA,p.Trp83*,para-aminosalicylic_acid,No

thyA,p.Trp98*,para-aminosalicylic_acid,No

thyA,p.Tyr36Cys,para-aminosalicylic_acid,No

thyA,p.Val77Phe,para-aminosalicylic_acid,Yes

thyX,c.-16C>T,para-aminosalicylic_acid,Yes

panD,c.393del,pyrazinamide,No

panD,p.Ala128Ser,pyrazinamide,No

panD,p.Glu126*,pyrazinamide,No

panD,p.Glu130Gly,pyrazinamide,No

panD,p.His21Arg,pyrazinamide,No

panD,p.Ile49Val,pyrazinamide,Yes

panD,p.Leu136Arg,pyrazinamide,No

panD,p.Met117Ile,pyrazinamide,Yes

panD,p.Val138Ala,pyrazinamide,Yes

panD,p.Val138Glu,pyrazinamide,No

panD,p.Val138Gly,pyrazinamide,No

pncA,c.101_102insT,pyrazinamide,No

pncA,c.-10T>C,pyrazinamide,Yes

pncA,c.1_11del,pyrazinamide,No

pncA,c.117_118insC,pyrazinamide,No

pncA,c.118_150del,pyrazinamide,No

pncA,c.-11A>C,pyrazinamide,Yes

pncA,c.-11A>G,pyrazinamide,Yes

pncA,c.12_14del,pyrazinamide,Yes

pncA,c.-12T>C,pyrazinamide,Yes

pncA,c.-12T>G,pyrazinamide,Yes

pncA,c.137_138insG,pyrazinamide,No

pncA,c.158del,pyrazinamide,No

pncA,c.16_17insC,pyrazinamide,No

pncA,c.161del,pyrazinamide,No

pncA,c.162_164del,pyrazinamide,Yes

pncA,c.162del,pyrazinamide,No

pncA,c.163_164insT,pyrazinamide,No

pncA,c.172del,pyrazinamide,No

pncA,c.189_200del,pyrazinamide,Yes

pncA,c.1_8del,pyrazinamide,No

pncA,c.193_194insA,pyrazinamide,No

pncA,c.194_195insA,pyrazinamide,Yes

pncA,c.210_211insACC,pyrazinamide,No

pncA,c.210_211insC,pyrazinamide,No

pncA,c.219_220insCGCATTGCCG,pyrazinamide,No

pncA,c.222_223insG,pyrazinamide,No

pncA,c.239del,pyrazinamide,No

pncA,c.250_251insC,pyrazinamide,No

pncA,c.272_276del,pyrazinamide,Yes

pncA,c.288_289insT,pyrazinamide,No

pncA,c.288del,pyrazinamide,No

pncA,c.28del,pyrazinamide,No

pncA,c.302_303insA,pyrazinamide,No

pncA,c.302_303insG,pyrazinamide,No

pncA,c.306_309del,pyrazinamide,Yes

pncA,c.307_308insC,pyrazinamide,No

pncA,c.307_311del,pyrazinamide,No

pncA,c.312del,pyrazinamide,No

pncA,c.315_316insG,pyrazinamide,No

pncA,c.341del,pyrazinamide,No

pncA,c.369_370insAG,pyrazinamide,No

pncA,c.375_389del,pyrazinamide,Yes

pncA,c.379_389del,pyrazinamide,No

pncA,c.380_388del,pyrazinamide,Yes

pncA,c.381_382del,pyrazinamide,No

pncA,c.383_384insAG,pyrazinamide,No

pncA,c.386_388del,pyrazinamide,No

pncA,c.386_389del,pyrazinamide,Yes

pncA,c.389_390insAGGTCGATG,pyrazinamide,No

pncA,c.389_390insGAGGTCGAT,pyrazinamide,No

pncA,c.389del,pyrazinamide,No

pncA,c.391del,pyrazinamide,No

pncA,c.392_393insGG,pyrazinamide,No

pncA,c.392_393insG,pyrazinamide,No

pncA,c.393_394insG,pyrazinamide,Yes

pncA,c.395_405del,pyrazinamide,No

pncA,c.395del,pyrazinamide,No

pncA,c.398_399insT,pyrazinamide,No

pncA,c.404_405insC,pyrazinamide,No

pncA,c.406del,pyrazinamide,No

pncA,c.408_409insC,pyrazinamide,No

pncA,c.415_416insG,pyrazinamide,No

pncA,c.416_417del,pyrazinamide,No

pncA,c.416del,pyrazinamide,No

pncA,c.421_422insGG,pyrazinamide,No

pncA,c.421_422insG,pyrazinamide,No

pncA,c.422del,pyrazinamide,No

pncA,c.429_430insGG,pyrazinamide,No

pncA,c.436del,pyrazinamide,No

pncA,c.443del,pyrazinamide,No

pncA,c.446_453del,pyrazinamide,No

pncA,c.452del,pyrazinamide,No

pncA,c.457_458insC,pyrazinamide,No

pncA,c.466_467insT,pyrazinamide,No

pncA,c.471_472insA,pyrazinamide,No

pncA,c.475del,pyrazinamide,No

pncA,c.47del,pyrazinamide,No

pncA,c.481_482insTGAC,pyrazinamide,No

pncA,c.495del,pyrazinamide,No

pncA,c.502_503insGC,pyrazinamide,No

pncA,c.512del,pyrazinamide,No

pncA,c.518_519insG,pyrazinamide,No

pncA,c.521_522insT,pyrazinamide,No

pncA,c.533_534insC,pyrazinamide,No

pncA,c.53_54insGG,pyrazinamide,No

pncA,c.59del,pyrazinamide,No

pncA,c.64del,pyrazinamide,No

pncA,c.68_78del,pyrazinamide,Yes

pncA,c.70del,pyrazinamide,No

pncA,c.71del,pyrazinamide,No

pncA,c.-7T>C,pyrazinamide,Yes

pncA,c.84del,pyrazinamide,No

pncA,c.88_111del,pyrazinamide,No

pncA,frameshift,pyrazinamide,No

pncA,large_deletion,pyrazinamide,No

pncA,p.Ala102Thr,pyrazinamide,Yes

pncA,p.Ala134Ser,pyrazinamide,No

pncA,p.Ala134Val,pyrazinamide,Yes

pncA,p.Ala143Asp,pyrazinamide,Yes

pncA,p.Ala143Pro,pyrazinamide,Yes

pncA,p.Ala143Thr,pyrazinamide,Yes

pncA,p.Ala146Glu,pyrazinamide,Yes

pncA,p.Ala146Thr,pyrazinamide,Yes

pncA,p.Ala146Val,pyrazinamide,Yes

pncA,p.Ala161Pro,pyrazinamide,No

pncA,p.Ala165Thr,pyrazinamide,No

pncA,p.Ala171Glu,pyrazinamide,Yes

pncA,p.Ala171Pro,pyrazinamide,Yes

pncA,p.Ala171Thr,pyrazinamide,Yes

pncA,p.Ala171Val,pyrazinamide,Yes

pncA,p.Ala26Gly,pyrazinamide,No

pncA,p.Ala28Asp,pyrazinamide,No

pncA,p.Ala3Glu,pyrazinamide,Yes

pncA,p.Ala3Pro,pyrazinamide,No

pncA,p.Ala46Glu,pyrazinamide,Yes

pncA,p.Ala46Pro,pyrazinamide,Yes

pncA,p.Ala46Val,pyrazinamide,Yes

pncA,p.Ala79Gly,pyrazinamide,No

pncA,p.Arg121Pro,pyrazinamide,Yes

pncA,p.Arg123Pro,pyrazinamide,Yes

pncA,p.Arg140Gly,pyrazinamide,No

pncA,p.Arg140His,pyrazinamide,No

pncA,p.Arg140Pro,pyrazinamide,Yes

pncA,p.Arg140Ser,pyrazinamide,No

pncA,p.Arg148Ser,pyrazinamide,No

pncA,p.Arg154Gly,pyrazinamide,Yes

pncA,p.Arg154Met,pyrazinamide,No

pncA,p.Asn118Thr,pyrazinamide,No

pncA,p.Asp12Ala,pyrazinamide,Yes

pncA,p.Asp12Asn,pyrazinamide,Yes

pncA,p.Asp12Glu,pyrazinamide,Yes

pncA,p.Asp12Gly,pyrazinamide,Yes

pncA,p.Asp136Asn,pyrazinamide,Yes

pncA,p.Asp136Gly,pyrazinamide,Yes

pncA,p.Asp136His,pyrazinamide,No

pncA,p.Asp136Tyr,pyrazinamide,Yes

pncA,p.Asp145Glu,pyrazinamide,Yes

pncA,p.Asp49Ala,pyrazinamide,Yes

pncA,p.Asp49Asn,pyrazinamide,Yes

pncA,p.Asp49Glu,pyrazinamide,Yes

pncA,p.Asp49Gly,pyrazinamide,Yes

pncA,p.Asp49His,pyrazinamide,No

pncA,p.Asp49Tyr,pyrazinamide,Yes

pncA,p.Asp49Val,pyrazinamide,No

pncA,p.Asp53Ala,pyrazinamide,No

pncA,p.Asp53Asn,pyrazinamide,No

pncA,p.Asp63Ala,pyrazinamide,Yes

pncA,p.Asp63Gly,pyrazinamide,Yes

pncA,p.Asp63His,pyrazinamide,Yes

pncA,p.Asp8Ala,pyrazinamide,Yes

pncA,p.Asp8Asn,pyrazinamide,Yes

pncA,p.Asp8Glu,pyrazinamide,Yes

pncA,p.Asp8Gly,pyrazinamide,Yes

pncA,p.Asp8Tyr,pyrazinamide,No

pncA,p.Cys138Arg,pyrazinamide,Yes

pncA,p.Cys138*,pyrazinamide,No

pncA,p.Cys138Ser,pyrazinamide,No

pncA,p.Cys138Tyr,pyrazinamide,Yes

pncA,p.Cys14Arg,pyrazinamide,Yes

pncA,p.Cys14Gly,pyrazinamide,Yes

pncA,p.Cys14*,pyrazinamide,No

pncA,p.Cys14Trp,pyrazinamide,Yes

pncA,p.Cys14Tyr,pyrazinamide,Yes

pncA,p.Cys72Arg,pyrazinamide,Yes

pncA,p.Cys72*,pyrazinamide,No

pncA,p.Cys72Trp,pyrazinamide,No

pncA,p.Cys72Tyr,pyrazinamide,Yes

pncA,p.Gln10Arg,pyrazinamide,Yes

pncA,p.Gln10His,pyrazinamide,Yes

pncA,p.Gln10Lys,pyrazinamide,No

pncA,p.Gln10Pro,pyrazinamide,Yes

pncA,p.Gln10*,pyrazinamide,No

pncA,p.Gln141Pro,pyrazinamide,Yes

pncA,p.Gln141*,pyrazinamide,No

pncA,p.Glu107*,pyrazinamide,No

pncA,p.Glu174Gly,pyrazinamide,Yes

pncA,p.Glu181Asp,pyrazinamide,No

pncA,p.Glu37*,pyrazinamide,No

pncA,p.Gly105Arg,pyrazinamide,Yes

pncA,p.Gly105Asp,pyrazinamide,Yes

pncA,p.Gly105Val,pyrazinamide,Yes

pncA,p.Gly108Arg,pyrazinamide,Yes

pncA,p.Gly132Ala,pyrazinamide,Yes

pncA,p.Gly132Asp,pyrazinamide,Yes

pncA,p.Gly132Ser,pyrazinamide,Yes

pncA,p.Gly132Val,pyrazinamide,No

pncA,p.Gly162Asp,pyrazinamide,Yes

pncA,p.Gly17Asp,pyrazinamide,Yes

pncA,p.Gly17Val,pyrazinamide,No

pncA,p.Gly23Val,pyrazinamide,No

pncA,p.Gly24Arg,pyrazinamide,Yes

pncA,p.Gly24Asp,pyrazinamide,Yes

pncA,p.Gly78Asp,pyrazinamide,No

pncA,p.Gly78Cys,pyrazinamide,Yes

pncA,p.Gly78Ser,pyrazinamide,Yes

pncA,p.Gly78Val,pyrazinamide,Yes

pncA,p.Gly97Arg,pyrazinamide,Yes

pncA,p.Gly97Asp,pyrazinamide,Yes

pncA,p.Gly97Cys,pyrazinamide,Yes

pncA,p.Gly97Ser,pyrazinamide,Yes

pncA,p.His137Arg,pyrazinamide,Yes

pncA,p.His137Pro,pyrazinamide,No

pncA,p.His43Pro,pyrazinamide,Yes

pncA,p.His51Arg,pyrazinamide,Yes

pncA,p.His51Asn,pyrazinamide,Yes

pncA,p.His51Asp,pyrazinamide,Yes

pncA,p.His51Gln,pyrazinamide,Yes

pncA,p.His51Pro,pyrazinamide,Yes

pncA,p.His51Tyr,pyrazinamide,Yes

pncA,p.His57Arg,pyrazinamide,Yes

pncA,p.His57Asn,pyrazinamide,No

pncA,p.His57Asp,pyrazinamide,Yes

pncA,p.His57Leu,pyrazinamide,No

pncA,p.His57Pro,pyrazinamide,Yes

pncA,p.His57Tyr,pyrazinamide,Yes

pncA,p.His71Arg,pyrazinamide,Yes

pncA,p.His71Asn,pyrazinamide,No

pncA,p.His71Asp,pyrazinamide,No

pncA,p.His71Gln,pyrazinamide,Yes

pncA,p.His71Tyr,pyrazinamide,Yes

pncA,p.His82Arg,pyrazinamide,Yes

pncA,p.His82Asp,pyrazinamide,Yes

pncA,p.His82Leu,pyrazinamide,No

pncA,p.His82Tyr,pyrazinamide,No

pncA,p.Ile133Asn,pyrazinamide,No

pncA,p.Ile133Thr,pyrazinamide,Yes

pncA,p.Ile31Ser,pyrazinamide,Yes

pncA,p.Ile5Ser,pyrazinamide,Yes

pncA,p.Ile5Thr,pyrazinamide,Yes

pncA,p.Ile6Met,pyrazinamide,Yes

pncA,p.Ile6Ser,pyrazinamide,Yes

pncA,p.Ile6Thr,pyrazinamide,Yes

pncA,p.Ile90Ser,pyrazinamide,Yes

pncA,p.Leu116Arg,pyrazinamide,Yes

pncA,p.Leu116Pro,pyrazinamide,Yes

pncA,p.Leu116Val,pyrazinamide,No

pncA,p.Leu120Pro,pyrazinamide,Yes

pncA,p.Leu151Ser,pyrazinamide,Yes

pncA,p.Leu156Pro,pyrazinamide,Yes

pncA,p.Leu159Arg,pyrazinamide,Yes

pncA,p.Leu159Pro,pyrazinamide,Yes

pncA,p.Leu159Val,pyrazinamide,Yes

pncA,p.Leu172Arg,pyrazinamide,Yes

pncA,p.Leu172Pro,pyrazinamide,Yes

pncA,p.Leu182Ser,pyrazinamide,Yes

pncA,p.Leu19Arg,pyrazinamide,No

pncA,p.Leu19Pro,pyrazinamide,Yes

pncA,p.Leu27Pro,pyrazinamide,Yes

pncA,p.Leu35Pro,pyrazinamide,Yes

pncA,p.Leu4Ser,pyrazinamide,Yes

pncA,p.Leu4Trp,pyrazinamide,Yes

pncA,p.Leu85Arg,pyrazinamide,Yes

pncA,p.Leu85Pro,pyrazinamide,Yes

pncA,p.Lys48Glu,pyrazinamide,Yes

pncA,p.Lys48Thr,pyrazinamide,Yes

pncA,p.Lys96Arg,pyrazinamide,Yes

pncA,p.Lys96Asn,pyrazinamide,Yes

pncA,p.Lys96Gln,pyrazinamide,Yes

pncA,p.Lys96Glu,pyrazinamide,Yes

pncA,p.Lys96Thr,pyrazinamide,Yes

pncA,p.Met175Arg,pyrazinamide,No

pncA,p.Met175Ile,pyrazinamide,Yes

pncA,p.Met175Lys,pyrazinamide,Yes

pncA,p.Met175Thr,pyrazinamide,Yes

pncA,p.Met175Val,pyrazinamide,Yes

pncA,p.Met1Thr,pyrazinamide,Yes

pncA,p.Phe106Ser,pyrazinamide,Yes

pncA,p.Phe13Ile,pyrazinamide,Yes

pncA,p.Phe13Leu,pyrazinamide,Yes

pncA,p.Phe13Ser,pyrazinamide,Yes

pncA,p.Phe58Leu,pyrazinamide,Yes

pncA,p.Phe58Ser,pyrazinamide,Yes

pncA,p.Phe81Val,pyrazinamide,Yes

pncA,p.Phe94Cys,pyrazinamide,Yes

pncA,p.Phe94Leu,pyrazinamide,Yes

pncA,p.Phe94Ser,pyrazinamide,Yes

pncA,p.Pro54Gln,pyrazinamide,Yes

pncA,p.Pro54Leu,pyrazinamide,Yes

pncA,p.Pro54Thr,pyrazinamide,No

pncA,p.Pro62Arg,pyrazinamide,Yes

pncA,p.Pro62Gln,pyrazinamide,No

pncA,p.Pro62Leu,pyrazinamide,Yes

pncA,p.Pro62Ser,pyrazinamide,Yes

pncA,p.Pro69Arg,pyrazinamide,Yes

pncA,p.Pro69Leu,pyrazinamide,Yes

pncA,p.Ser104Arg,pyrazinamide,Yes

pncA,p.Ser104Gly,pyrazinamide,Yes

pncA,p.Ser164Pro,pyrazinamide,Yes

pncA,p.Ser179Arg,pyrazinamide,No

pncA,p.Ser185Ile,pyrazinamide,No

pncA,p.Ser185Thr,pyrazinamide,No

pncA,p.Ser18Pro,pyrazinamide,Yes

pncA,p.Ser32Ile,pyrazinamide,Yes

pncA,p.Ser59Phe,pyrazinamide,Yes

pncA,p.Ser59Pro,pyrazinamide,Yes

pncA,p.Ser66Pro,pyrazinamide,Yes

pncA,p.Ser67Pro,pyrazinamide,Yes

pncA,p.Ser88*,pyrazinamide,No

pncA,p.Thr114Ala,pyrazinamide,No

pncA,p.Thr114Pro,pyrazinamide,Yes

pncA,p.Thr135Pro,pyrazinamide,Yes

pncA,p.Thr142Ala,pyrazinamide,Yes

pncA,p.Thr142Lys,pyrazinamide,Yes

pncA,p.Thr142Met,pyrazinamide,Yes

pncA,p.Thr142Pro,pyrazinamide,Yes

pncA,p.Thr153Asn,pyrazinamide,No

pncA,p.Thr160Arg,pyrazinamide,Yes

pncA,p.Thr160Pro,pyrazinamide,Yes

pncA,p.Thr168Asn,pyrazinamide,Yes

pncA,p.Thr168Pro,pyrazinamide,Yes

pncA,p.Thr47Ala,pyrazinamide,Yes

pncA,p.Thr47Pro,pyrazinamide,Yes

pncA,p.Thr47Ser,pyrazinamide,No

pncA,p.Thr61Pro,pyrazinamide,Yes

pncA,p.Thr76Ile,pyrazinamide,Yes

pncA,p.Thr76Pro,pyrazinamide,Yes

pncA,p.Trp119Arg,pyrazinamide,Yes

pncA,p.Trp119Cys,pyrazinamide,No

pncA,p.Trp119*,pyrazinamide,No

pncA,p.Trp119Ser,pyrazinamide,Yes

pncA,p.Trp68Arg,pyrazinamide,Yes

pncA,p.Trp68Cys,pyrazinamide,Yes

pncA,p.Trp68Gly,pyrazinamide,Yes

pncA,p.Trp68Leu,pyrazinamide,Yes

pncA,p.Trp68*,pyrazinamide,No

pncA,p.Trp68Ser,pyrazinamide,Yes

pncA,p.Tyr103Cys,pyrazinamide,Yes

pncA,p.Tyr103His,pyrazinamide,Yes

pncA,p.Tyr103*,pyrazinamide,No

pncA,p.Tyr103Ser,pyrazinamide,No

pncA,p.Tyr34Asp,pyrazinamide,Yes

pncA,p.Tyr34*,pyrazinamide,No

pncA,p.Tyr34Ser,pyrazinamide,Yes

pncA,p.Tyr41His,pyrazinamide,No

pncA,p.Tyr41*,pyrazinamide,No

pncA,p.Tyr64Asp,pyrazinamide,Yes

pncA,p.Tyr95*,pyrazinamide,No

pncA,p.Tyr99*,pyrazinamide,No

pncA,p.Val125Asp,pyrazinamide,Yes

pncA,p.Val125Gly,pyrazinamide,Yes

pncA,p.Val128Gly,pyrazinamide,Yes

pncA,p.Val130Ala,pyrazinamide,Yes

pncA,p.Val130Glu,pyrazinamide,Yes

pncA,p.Val130Gly,pyrazinamide,Yes

pncA,p.Val131Phe,pyrazinamide,Yes

pncA,p.Val139Ala,pyrazinamide,Yes

pncA,p.Val139Gly,pyrazinamide,Yes

pncA,p.Val139Leu,pyrazinamide,Yes

pncA,p.Val139Met,pyrazinamide,Yes

pncA,p.Val155Ala,pyrazinamide,Yes

pncA,p.Val155Gly,pyrazinamide,Yes

pncA,p.Val155Leu,pyrazinamide,No

pncA,p.Val155Met,pyrazinamide,Yes

pncA,p.Val180Gly,pyrazinamide,Yes

pncA,p.Val180Phe,pyrazinamide,Yes

pncA,p.Val21Ala,pyrazinamide,Yes

pncA,p.Val21Gly,pyrazinamide,Yes

pncA,p.Val44Gly,pyrazinamide,Yes

pncA,p.Val45Gly,pyrazinamide,Yes

pncA,p.Val7Asp,pyrazinamide,No

pncA,p.Val7Gly,pyrazinamide,Yes

pncA,p.Val7Ile,pyrazinamide,Yes

pncA,p.Val7Leu,pyrazinamide,Yes

pncA,p.Val7Phe,pyrazinamide,Yes

pncA,p.Val9Ala,pyrazinamide,Yes

pncA,p.Val9Gly,pyrazinamide,Yes

pncA,p.Val9Leu,pyrazinamide,No

rpsA,p.Arg474Leu,pyrazinamide,No

rpsA,p.Arg474Trp,pyrazinamide,No

rpsA,p.Glu433Asp,pyrazinamide,No

rpoB,any_missense_codon_445,rifampicin,No

rpoB,any_missense_codon_450,rifampicin,No

rpoB,c.1275_1280del,rifampicin,No

rpoB,c.1276_1281del,rifampicin,No

rpoB,c.1282_1290del,rifampicin,Yes

rpoB,c.1293_1294insTTCATG,rifampicin,No

rpoB,c.1293_1294insTTC,rifampicin,No

rpoB,c.1294_1299del,rifampicin,No

rpoB,c.1295_1303del,rifampicin,Yes

rpoB,c.1296_1297insCGG,rifampicin,No

rpoB,c.1296_1297insTTC,rifampicin,No

rpoB,c.1297_1299del,rifampicin,No

rpoB,c.1297_1305del,rifampicin,No

rpoB,c.1299_1300insTTC,rifampicin,No

rpoB,c.1299_1301del,rifampicin,No

rpoB,c.1299_1310del,rifampicin,No

rpoB,c.1300_1311del,rifampicin,No

rpoB,c.1302_1307del,rifampicin,Yes

rpoB,c.1303_1308del,rifampicin,No

rpoB,c.1306_1308del,rifampicin,Yes

rpoB,c.1306_1311del,rifampicin,No

rpoB,c.1308_1313del,rifampicin,No

rpoB,c.1312_1314del,rifampicin,No

rpoB,c.1327_1332del,rifampicin,Yes

rpoB,c.1336_1338del,rifampicin,No

rpoB,c.1648_1649insAGC,rifampicin,No

rpoB,c.289_290insTGTCGT,rifampicin,No

rpoB,p.Ala286Val,rifampicin,Yes

rpoB,p.Arg447His,rifampicin,No

rpoB,p.Arg447Pro,rifampicin,No

rpoB,p.Arg448Lys,rifampicin,Yes

rpoB,p.Arg552Cys,rifampicin,Yes

rpoB,p.Asn437Asp,rifampicin,Yes

rpoB,p.Asn437His,rifampicin,Yes

rpoB,p.Asn437Ile,rifampicin,No

rpoB,p.Asn437Thr,rifampicin,No

rpoB,p.Asn437Tyr,rifampicin,Yes

rpoB,p.Asn438Lys,rifampicin,No

rpoB,p.Asp435Ala,rifampicin,Yes

rpoB,p.Asp435Ala,rifampicin,Yes

rpoB,p.Asp435Asn,rifampicin,Yes

rpoB,p.Asp435Glu,rifampicin,Yes

rpoB,p.Asp435Gly,rifampicin,Yes

rpoB,p.Asp435His,rifampicin,Yes

rpoB,p.Asp435Phe,rifampicin,Yes

rpoB,p.Asp435Tyr,rifampicin,Yes

rpoB,p.Asp435Val,rifampicin,Yes

rpoB,p.Gln409His,rifampicin,No

rpoB,p.Gln429His,rifampicin,Yes

rpoB,p.Gln429Lys,rifampicin,No

rpoB,p.Gln432Arg,rifampicin,No

rpoB,p.Gln432Glu,rifampicin,Yes

rpoB,p.Gln432His,rifampicin,Yes

rpoB,p.Gln432Leu,rifampicin,Yes

rpoB,p.Gln432Lys,rifampicin,Yes

rpoB,p.Gln432Pro,rifampicin,Yes

rpoB,p.Gln432*,rifampicin,No

rpoB,p.Gln436His,rifampicin,No

rpoB,p.Gln436Leu,rifampicin,No

rpoB,p.Glu423Ala,rifampicin,No

rpoB,p.Glu460Gly,rifampicin,Yes

rpoB,p.Glu481Gly,rifampicin,No

rpoB,p.Glu592Asp,rifampicin,No

rpoB,p.Glu761Asp,rifampicin,Yes

rpoB,p.Gly426Asp,rifampicin,No

rpoB,p.Gly426Ser,rifampicin,No

rpoB,p.Gly442Ala,rifampicin,No

rpoB,p.Gly442Trp,rifampicin,No

rpoB,p.Gly981Asp,rifampicin,Yes

rpoB,p.Ile480Thr,rifampicin,Yes

rpoB,p.Ile480Val,rifampicin,Yes

rpoB,p.Ile491Phe,rifampicin,Yes

rpoB,p.Leu430Arg,rifampicin,Yes

rpoB,p.Leu430Pro,rifampicin,Yes

rpoB,p.Leu430Val,rifampicin,Yes

rpoB,p.Leu440Leu,rifampicin,No

rpoB,p.Leu440Met,rifampicin,No

rpoB,p.Leu440Pro,rifampicin,No

rpoB,p.Leu443Ser,rifampicin,No

rpoB,p.Leu443Trp,rifampicin,Yes

rpoB,p.Leu452Pro,rifampicin,Yes

rpoB,p.Leu457Pro,rifampicin,No

rpoB,p.Leu464Met,rifampicin,Yes

rpoB,p.Leu490Val,rifampicin,No

rpoB,p.Lys446Asn,rifampicin,No

rpoB,p.Lys446Gln,rifampicin,Yes

rpoB,p.Met434Ile,rifampicin,Yes

rpoB,p.Met434Thr,rifampicin,No

rpoB,p.Phe424Leu,rifampicin,Yes

rpoB,p.Phe424Ser,rifampicin,No

rpoB,p.Phe424Val,rifampicin,Yes

rpoB,p.Phe433Leu,rifampicin,No

rpoB,p.Phe433Val,rifampicin,No

rpoB,p.Pro454Arg,rifampicin,Yes

rpoB,p.Pro454His,rifampicin,Yes

rpoB,p.Pro454Leu,rifampicin,Yes

rpoB,p.Pro454Ser,rifampicin,No

rpoB,p.Pro483Leu,rifampicin,Yes

rpoB,p.Ser428Arg,rifampicin,Yes

rpoB,p.Ser428Ile,rifampicin,No

rpoB,p.Ser428Thr,rifampicin,Yes

rpoB,p.Ser431Arg,rifampicin,Yes

rpoB,p.Ser431Gly,rifampicin,Yes

rpoB,p.Ser431Ile,rifampicin,No

rpoB,p.Ser431Thr,rifampicin,Yes

rpoB,p.Ser441Gln,rifampicin,Yes

rpoB,p.Ser441Leu,rifampicin,Yes

rpoB,p.Ser441Met,rifampicin,Yes

rpoB,p.Ser441Trp,rifampicin,No

rpoB,p.Ser441Val,rifampicin,Yes

rpoB,p.Ser472Ala,rifampicin,No

rpoB,p.Ser493Leu,rifampicin,Yes

rpoB,p.Thr400Ala,rifampicin,Yes

rpoB,p.Thr427Ala,rifampicin,No

rpoB,p.Thr427Pro,rifampicin,Yes

rpoB,p.Thr427Ser,rifampicin,Yes

rpoB,p.Thr444Ile,rifampicin,Yes

rpoB,p.Thr444Pro,rifampicin,Yes

rpoB,p.Thr482Pro,rifampicin,No

rpoB,p.Val170Phe,rifampicin,Yes

rpoC,p.Asp485Asn,rifampicin,Yes

rpoC,p.Asp735Asn,rifampicin,Yes

rpoC,p.Asp747Ala,rifampicin,Yes

rpoC,p.Gly332Arg,rifampicin,Yes

rpoC,p.Ile491Thr,rifampicin,Yes

rpoC,p.Ile885Val,rifampicin,Yes

rpoC,p.Leu527Val,rifampicin,Yes

rpoC,p.Phe452Ser,rifampicin,Yes

gid,c.102del,streptomycin,No

gid,c.103_104insG,streptomycin,No

gid,c.107del,streptomycin,No

gid,c.115del,streptomycin,No

gid,c.136del,streptomycin,No

gid,c.157del,streptomycin,No

gid,c.225_226insT,streptomycin,No

gid,c.294_295insAC,streptomycin,No

gid,c.297_298insA,streptomycin,No

gid,c.326del,streptomycin,No

gid,c.351del,streptomycin,No

gid,c.352_353insG,streptomycin,No

gid,c.366_367del,streptomycin,Yes

gid,c.386del,streptomycin,No

gid,c.390del,streptomycin,No

gid,c.400_401insT,streptomycin,No

gid,c.446_447insA,streptomycin,No

gid,c.450del,streptomycin,No

gid,c.452del,streptomycin,No

gid,c.455del,streptomycin,No

gid,c.471del,streptomycin,No

gid,c.519_520insA,streptomycin,No

gid,c.554_555insG,streptomycin,No

gid,c.559_572del,streptomycin,Yes

gid,c.58_59insT,streptomycin,No

gid,c.601del,streptomycin,No

gid,large_deletion,streptomycin,No

gid,p.Ala80Pro,streptomycin,Yes

rpsL,p.Arg86Pro,streptomycin,No

rpsL,p.Arg86Trp,streptomycin,No

rpsL,p.Arg9His,streptomycin,No

rpsL,p.Gly84Val,streptomycin,No

rpsL,p.Lys43Arg,streptomycin,Yes

rpsL,p.Lys43Thr,streptomycin,Yes

rpsL,p.Lys51Asn,streptomycin,No

rpsL,p.Lys88Arg,streptomycin,Yes

rpsL,p.Lys88Gln,streptomycin,Yes

rpsL,p.Lys88Met,streptomycin,Yes

rpsL,p.Lys88Thr,streptomycin,Yes

rpsL,p.Thr40Ile,streptomycin,No

rpsL,p.Thr41Ser,streptomycin,No

rpsL,p.Val52Gly,streptomycin,No

rpsL,p.Val87Leu,streptomycin,No

rpsL,p.Val93Met,streptomycin,No

rrs,r.190g>a,streptomycin,Yes

rrs,r.277g>c,streptomycin,Yes

rrs,r.427g>c,streptomycin,No

rrs,r.427g>t,streptomycin,No

rrs,r.462c>t,streptomycin,Yes

rrs,r.513c>t,streptomycin,Yes

rrs,r.514a>c,streptomycin,Yes

rrs,r.514a>t,streptomycin,Yes

rrs,r.516c>t,streptomycin,No

rrs,r.517c>t,streptomycin,Yes

rrs,r.628g>c,streptomycin,No

rrs,r.799c>t,streptomycin,Yes

rrs,r.888g>a,streptomycin,Yes

rrs,r.905c>a,streptomycin,Yes

rrs,r.905c>g,streptomycin,Yes

rrs,r.906a>g,streptomycin,Yes

rrs,r.907a>c,streptomycin,Yes

rrs,r.907a>t,streptomycin,Yes

rrs,r.908a>g,streptomycin,Yes