NAME GS
follow link to MSigDB GS DETAILS SIZE ES NES NOM p-val FDR q-val FWER p-val RANK AT MAX LEADING EDGE HALLMARK_INTERFERON_ALPHA_RESPONSE%MSIGDB_C2%HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE%MSIGDB_C2%HALLMARK_INTERFERON_ALPHA_RESPONSE Details ... 94 -0.8695712 -3.0369804 0.0 0.0 0.0 1037 tags=72%, list=7%, signal=77% HALLMARK_INTERFERON_GAMMA_RESPONSE%MSIGDB_C2%HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE%MSIGDB_C2%HALLMARK_INTERFERON_GAMMA_RESPONSE Details ... 197 -0.76218176 -2.9976768 0.0 0.0 0.0 1296 tags=55%, list=9%, signal=59% INTERFERON SIGNALING%REACTOME DATABASE ID RELEASE 60%913531 INTERFERON SIGNALING%REACTOME DATABASE ID RELEASE 60%913531 Details ... 166 -0.7083328 -2.7320342 0.0 0.0 0.0 1186 tags=41%, list=8%, signal=44% INTERFERON ALPHA BETA SIGNALING%REACTOME DATABASE ID RELEASE 60%909733 INTERFERON ALPHA BETA SIGNALING%REACTOME DATABASE ID RELEASE 60%909733 Details ... 52 -0.8341003 -2.6797993 0.0 0.0 0.0 1141 tags=65%, list=8%, signal=70% HALLMARK_E2F_TARGETS%MSIGDB_C2%HALLMARK_E2F_TARGETS HALLMARK_E2F_TARGETS%MSIGDB_C2%HALLMARK_E2F_TARGETS Details ... 191 -0.6986505 -2.6685917 0.0 0.0 0.0 3080 tags=61%, list=20%, signal=76% CELLULAR RESPONSE TO TYPE I INTERFERON%GOBP%GO:0071357 CELLULAR RESPONSE TO TYPE I INTERFERON%GOBP%GO:0071357 Details ... 50 -0.83018 -2.612849 0.0 0.0 0.0 1141 tags=66%, list=8%, signal=71% MITOCHONDRIAL TRANSLATION TERMINATION%REACTOME%R-HSA-5419276.1 MITOCHONDRIAL TRANSLATION TERMINATION%REACTOME%R-HSA-5419276.1 Details ... 85 -0.74629915 -2.6126876 0.0 0.0 0.0 3028 tags=79%, list=20%, signal=98% TYPE I INTERFERON SIGNALING PATHWAY%GOBP%GO:0060337 TYPE I INTERFERON SIGNALING PATHWAY%GOBP%GO:0060337 Details ... 50 -0.83018 -2.6076517 0.0 0.0 0.0 1141 tags=66%, list=8%, signal=71% MITOTIC ANAPHASE%REACTOME DATABASE ID RELEASE 60%68882 MITOTIC ANAPHASE%REACTOME DATABASE ID RELEASE 60%68882 Details ... 162 -0.6777128 -2.605328 0.0 0.0 0.0 3357 tags=57%, list=22%, signal=73% MITOCHONDRIAL TRANSLATION%GOBP%GO:0032543 MITOCHONDRIAL TRANSLATION%GOBP%GO:0032543 Details ... 102 -0.7332446 -2.6029742 0.0 0.0 0.0 3028 tags=72%, list=20%, signal=89% RESPONSE TO TYPE I INTERFERON%GOBP%GO:0034340 RESPONSE TO TYPE I INTERFERON%GOBP%GO:0034340 Details ... 53 -0.8195193 -2.6016557 0.0 0.0 0.0 1141 tags=62%, list=8%, signal=67% INTERFERON-GAMMA-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060333 INTERFERON-GAMMA-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060333 Details ... 64 -0.78480697 -2.5994298 0.0 0.0 0.0 1186 tags=55%, list=8%, signal=59% MITOCHONDRIAL TRANSLATIONAL TERMINATION%GOBP%GO:0070126 MITOCHONDRIAL TRANSLATIONAL TERMINATION%GOBP%GO:0070126 Details ... 85 -0.74629915 -2.5989363 0.0 0.0 0.0 3028 tags=79%, list=20%, signal=98% MITOCHONDRIAL TRANSLATIONAL ELONGATION%GOBP%GO:0070125 MITOCHONDRIAL TRANSLATIONAL ELONGATION%GOBP%GO:0070125 Details ... 85 -0.7500577 -2.5959222 0.0 0.0 0.0 3028 tags=80%, list=20%, signal=99% SEPARATION OF SISTER CHROMATIDS%REACTOME DATABASE ID RELEASE 60%2467813 SEPARATION OF SISTER CHROMATIDS%REACTOME DATABASE ID RELEASE 60%2467813 Details ... 154 -0.68161047 -2.5955727 0.0 0.0 0.0 3357 tags=58%, list=22%, signal=73% MITOTIC METAPHASE AND ANAPHASE%REACTOME%R-HSA-2555396.2 MITOTIC METAPHASE AND ANAPHASE%REACTOME%R-HSA-2555396.2 Details ... 163 -0.67901236 -2.591474 0.0 0.0 0.0 3357 tags=58%, list=22%, signal=73% INTERFERON GAMMA SIGNALING%REACTOME%R-HSA-877300.1 INTERFERON GAMMA SIGNALING%REACTOME%R-HSA-877300.1 Details ... 82 -0.74543154 -2.5869071 0.0 0.0 0.0 1186 tags=48%, list=8%, signal=51% MITOCHONDRIAL TRANSLATION ELONGATION%REACTOME%R-HSA-5389840.1 MITOCHONDRIAL TRANSLATION ELONGATION%REACTOME%R-HSA-5389840.1 Details ... 85 -0.75344193 -2.5861878 0.0 0.0 0.0 3028 tags=81%, list=20%, signal=101% MITOCHONDRIAL TRANSLATION%REACTOME DATABASE ID RELEASE 60%5368287 MITOCHONDRIAL TRANSLATION%REACTOME DATABASE ID RELEASE 60%5368287 Details ... 91 -0.74287534 -2.5740318 0.0 0.0 0.0 3028 tags=77%, list=20%, signal=95% TRANSLATIONAL TERMINATION%GOBP%GO:0006415 TRANSLATIONAL TERMINATION%GOBP%GO:0006415 Details ... 92 -0.7396683 -2.5703301 0.0 0.0 0.0 3028 tags=75%, list=20%, signal=93% ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I%GOBP%GO:0042590 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I%GOBP%GO:0042590 75 -0.7412715 -2.5558307 0.0 0.0 0.0 1916 tags=57%, list=13%, signal=65% SYNTHESIS OF DNA%REACTOME%R-HSA-69239.2 SYNTHESIS OF DNA%REACTOME%R-HSA-69239.2 92 -0.7277243 -2.5356245 0.0 0.0 0.0 2247 tags=60%, list=15%, signal=70% TRANSLATIONAL ELONGATION%GOBP%GO:0006414 TRANSLATIONAL ELONGATION%GOBP%GO:0006414 99 -0.71115196 -2.523887 0.0 0.0 0.0 3028 tags=72%, list=20%, signal=89% MITOCHONDRIAL TRANSLATION INITIATION%REACTOME%R-HSA-5368286.1 MITOCHONDRIAL TRANSLATION INITIATION%REACTOME%R-HSA-5368286.1 85 -0.7499488 -2.523729 0.0 0.0 0.0 3028 tags=80%, list=20%, signal=99% ACTIVATION OF APC C AND APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME DATABASE ID RELEASE 60%176814 ACTIVATION OF APC C AND APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME DATABASE ID RELEASE 60%176814 73 -0.74134606 -2.5166268 0.0 0.0 0.0 2247 tags=56%, list=15%, signal=66% HALLMARK_MYC_TARGETS_V1%MSIGDB_C2%HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1%MSIGDB_C2%HALLMARK_MYC_TARGETS_V1 194 -0.64211357 -2.515662 0.0 0.0 0.0 3546 tags=53%, list=23%, signal=68% HALLMARK_OXIDATIVE_PHOSPHORYLATION%MSIGDB_C2%HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION%MSIGDB_C2%HALLMARK_OXIDATIVE_PHOSPHORYLATION 197 -0.6520349 -2.5139587 0.0 0.0 0.0 3106 tags=55%, list=20%, signal=69% POSITIVE REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:2000060 POSITIVE REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:2000060 83 -0.710044 -2.5138 0.0 0.0 0.0 2247 tags=48%, list=15%, signal=56% CELL CYCLE CHECKPOINTS%REACTOME DATABASE ID RELEASE 60%69620 CELL CYCLE CHECKPOINTS%REACTOME DATABASE ID RELEASE 60%69620 173 -0.6603069 -2.5136619 0.0 0.0 0.0 3379 tags=56%, list=22%, signal=71% APC:CDC20 MEDIATED DEGRADATION OF CELL CYCLE PROTEINS PRIOR TO SATISFATION OF THE CELL CYCLE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%179419 APC:CDC20 MEDIATED DEGRADATION OF CELL CYCLE PROTEINS PRIOR TO SATISFATION OF THE CELL CYCLE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%179419 70 -0.7341847 -2.511087 0.0 0.0 0.0 2247 tags=54%, list=15%, signal=63% REGULATION OF MITOTIC CELL CYCLE%REACTOME DATABASE ID RELEASE 60%453276 REGULATION OF MITOTIC CELL CYCLE%REACTOME DATABASE ID RELEASE 60%453276 83 -0.72840494 -2.5075464 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN%GOBP%GO:0002478 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN%GOBP%GO:0002478 159 -0.658661 -2.5074625 0.0 0.0 0.0 1916 tags=44%, list=13%, signal=50% M G1 TRANSITION%REACTOME DATABASE ID RELEASE 60%68874 M G1 TRANSITION%REACTOME DATABASE ID RELEASE 60%68874 76 -0.7375526 -2.5054252 0.0 0.0 0.0 2352 tags=63%, list=15%, signal=74% ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN%GOBP%GO:0048002 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN%GOBP%GO:0048002 168 -0.64412236 -2.5029685 0.0 0.0 0.0 1916 tags=42%, list=13%, signal=47% ANAPHASE-PROMOTING COMPLEX-DEPENDENT CATABOLIC PROCESS%GOBP%GO:0031145 ANAPHASE-PROMOTING COMPLEX-DEPENDENT CATABOLIC PROCESS%GOBP%GO:0031145 77 -0.73082 -2.5020342 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME DATABASE ID RELEASE 60%176409 APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME DATABASE ID RELEASE 60%176409 72 -0.7391791 -2.4995434 0.0 0.0 0.0 2247 tags=56%, list=15%, signal=65% RESPIRATORY ELECTRON TRANSPORT, ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING, AND HEAT PRODUCTION BY UNCOUPLING PROTEINS.%REACTOME%R-HSA-163200.1 RESPIRATORY ELECTRON TRANSPORT, ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING, AND HEAT PRODUCTION BY UNCOUPLING PROTEINS.%REACTOME%R-HSA-163200.1 104 -0.70423204 -2.4980776 0.0 0.0 0.0 3066 tags=69%, list=20%, signal=86% ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS ANTIGEN%GOBP%GO:0019884 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS ANTIGEN%GOBP%GO:0019884 163 -0.6592334 -2.4972959 0.0 0.0 0.0 1916 tags=44%, list=13%, signal=49% REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:2000058 REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:2000058 96 -0.6944362 -2.4955158 0.0 0.0 0.0 2247 tags=43%, list=15%, signal=50% DNA REPLICATION PRE-INITIATION%REACTOME%R-HSA-69002.2 DNA REPLICATION PRE-INITIATION%REACTOME%R-HSA-69002.2 76 -0.7375526 -2.4946203 0.0 0.0 0.0 2352 tags=63%, list=15%, signal=74% REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN MITOTIC CELL CYCLE%GOBP%GO:0051439 REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN MITOTIC CELL CYCLE%GOBP%GO:0051439 72 -0.74269533 -2.494618 0.0 0.0 0.0 2247 tags=57%, list=15%, signal=66% DNA REPLICATION%REACTOME%R-HSA-69306.1 DNA REPLICATION%REACTOME%R-HSA-69306.1 99 -0.72465307 -2.4882233 0.0 0.0 0.0 2247 tags=60%, list=15%, signal=69% APC C-MEDIATED DEGRADATION OF CELL CYCLE PROTEINS%REACTOME%R-HSA-174143.1 APC C-MEDIATED DEGRADATION OF CELL CYCLE PROTEINS%REACTOME%R-HSA-174143.1 83 -0.72840494 -2.4877095 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% REGULATION OF DNA REPLICATION%REACTOME%R-HSA-69304.2 REGULATION OF DNA REPLICATION%REACTOME%R-HSA-69304.2 68 -0.7363593 -2.486688 0.0 0.0 0.0 2247 tags=59%, list=15%, signal=69% G2 M CHECKPOINTS%REACTOME%R-HSA-69481.3 G2 M CHECKPOINTS%REACTOME%R-HSA-69481.3 140 -0.66623616 -2.484353 0.0 0.0 0.0 3379 tags=59%, list=22%, signal=75% ASSEMBLY OF THE PRE-REPLICATIVE COMPLEX%REACTOME DATABASE ID RELEASE 60%68867 ASSEMBLY OF THE PRE-REPLICATIVE COMPLEX%REACTOME DATABASE ID RELEASE 60%68867 60 -0.75160503 -2.4804428 0.0 0.0 0.0 2247 tags=62%, list=15%, signal=72% ER-PHAGOSOME PATHWAY%REACTOME DATABASE ID RELEASE 60%1236974 ER-PHAGOSOME PATHWAY%REACTOME DATABASE ID RELEASE 60%1236974 80 -0.72617507 -2.4705265 0.0 0.0 0.0 1584 tags=45%, list=10%, signal=50% ANTIGEN PROCESSING AND PRESENTATION%GOBP%GO:0019882 ANTIGEN PROCESSING AND PRESENTATION%GOBP%GO:0019882 192 -0.6320853 -2.46786 0.0 0.0 0.0 1916 tags=39%, list=13%, signal=44% POSITIVE REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN REGULATION OF MITOTIC CELL CYCLE TRANSITION%GOBP%GO:0051437 POSITIVE REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN REGULATION OF MITOTIC CELL CYCLE TRANSITION%GOBP%GO:0051437 74 -0.7271584 -2.4646294 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% NEGATIVE REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN MITOTIC CELL CYCLE%GOBP%GO:0051436 NEGATIVE REGULATION OF UBIQUITIN-PROTEIN LIGASE ACTIVITY INVOLVED IN MITOTIC CELL CYCLE%GOBP%GO:0051436 71 -0.74051195 -2.4618614 0.0 0.0 0.0 2247 tags=56%, list=15%, signal=66% G1 S TRANSITION%REACTOME%R-HSA-69206.2 G1 S TRANSITION%REACTOME%R-HSA-69206.2 121 -0.66952443 -2.4602292 0.0 0.0 0.0 2988 tags=58%, list=20%, signal=71% ORC1 REMOVAL FROM CHROMATIN%REACTOME DATABASE ID RELEASE 60%68949 ORC1 REMOVAL FROM CHROMATIN%REACTOME DATABASE ID RELEASE 60%68949 63 -0.7353776 -2.4576936 0.0 0.0 0.0 2247 tags=59%, list=15%, signal=69% DOWNSTREAM TCR SIGNALING%REACTOME%R-HSA-202424.3 DOWNSTREAM TCR SIGNALING%REACTOME%R-HSA-202424.3 92 -0.7016024 -2.4568698 0.0 0.0 0.0 2310 tags=52%, list=15%, signal=61% ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT%GOBP%GO:0002479 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT%GOBP%GO:0002479 72 -0.7389126 -2.455548 0.0 0.0 0.0 1916 tags=57%, list=13%, signal=65% REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904666 REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904666 88 -0.70452994 -2.4546545 0.0 0.0 0.0 2247 tags=48%, list=15%, signal=56% S PHASE%REACTOME%R-HSA-69242.2 S PHASE%REACTOME%R-HSA-69242.2 131 -0.66888195 -2.4543366 0.0 0.0 0.0 3042 tags=57%, list=20%, signal=71% RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0034341 RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0034341 110 -0.6648192 -2.4475405 0.0 0.0 0.0 2030 tags=48%, list=13%, signal=55% REGULATION OF APC C ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE%REACTOME DATABASE ID RELEASE 60%176408 REGULATION OF APC C ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE%REACTOME DATABASE ID RELEASE 60%176408 77 -0.7284623 -2.4461558 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% POSITIVE REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904668 POSITIVE REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904668 80 -0.7109147 -2.4450166 0.0 0.0 0.0 2247 tags=50%, list=15%, signal=58% NEGATIVE REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904667 NEGATIVE REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY%GOBP%GO:1904667 77 -0.7298231 -2.4438224 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=61% APC C:CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C:CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1%REACTOME%R-HSA-174178.2 APC C:CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C:CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1%REACTOME%R-HSA-174178.2 69 -0.73075134 -2.4423983 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=61% METABOLISM OF POLYAMINES%REACTOME%R-HSA-351202.2 METABOLISM OF POLYAMINES%REACTOME%R-HSA-351202.2 77 -0.708894 -2.4380517 0.0 0.0 0.0 3220 tags=60%, list=21%, signal=75% INTERLEUKIN-1 SIGNALING%REACTOME DATABASE ID RELEASE 60%446652 INTERLEUKIN-1 SIGNALING%REACTOME DATABASE ID RELEASE 60%446652 91 -0.6902505 -2.4300203 0.0 0.0 0.0 2988 tags=52%, list=20%, signal=64% CDC20:PHOSPHO-APC C MEDIATED DEGRADATION OF CYCLIN A%REACTOME%R-HSA-174184.2 CDC20:PHOSPHO-APC C MEDIATED DEGRADATION OF CYCLIN A%REACTOME%R-HSA-174184.2 69 -0.7318818 -2.4244235 0.0 0.0 0.0 2247 tags=54%, list=15%, signal=63% RESPIRATORY ELECTRON TRANSPORT%REACTOME%R-HSA-611105.3 RESPIRATORY ELECTRON TRANSPORT%REACTOME%R-HSA-611105.3 84 -0.70845276 -2.4233837 0.0 0.0 0.0 3616 tags=76%, list=24%, signal=99% CELLULAR PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043624 CELLULAR PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043624 116 -0.661488 -2.4211352 0.0 0.0 0.0 3028 tags=65%, list=20%, signal=80% TCR SIGNALING%REACTOME DATABASE ID RELEASE 60%202403 TCR SIGNALING%REACTOME DATABASE ID RELEASE 60%202403 112 -0.66123956 -2.4210882 0.0 0.0 0.0 3007 tags=59%, list=20%, signal=73% REMOVAL OF LICENSING FACTORS FROM ORIGINS%REACTOME%R-HSA-69300.2 REMOVAL OF LICENSING FACTORS FROM ORIGINS%REACTOME%R-HSA-69300.2 65 -0.7327443 -2.4120634 0.0 0.0 0.0 2247 tags=58%, list=15%, signal=68% SWITCHING OF ORIGINS TO A POST-REPLICATIVE STATE%REACTOME DATABASE ID RELEASE 60%69052 SWITCHING OF ORIGINS TO A POST-REPLICATIVE STATE%REACTOME DATABASE ID RELEASE 60%69052 63 -0.7353776 -2.4115295 0.0 0.0 0.0 2247 tags=59%, list=15%, signal=69% APC C:CDC20 MEDIATED DEGRADATION OF SECURIN%REACTOME%R-HSA-174154.2 APC C:CDC20 MEDIATED DEGRADATION OF SECURIN%REACTOME%R-HSA-174154.2 64 -0.734114 -2.4095762 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS I%GOBP%GO:0002474 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS I%GOBP%GO:0002474 90 -0.6877248 -2.4031227 0.0 0.0 0.0 1916 tags=49%, list=13%, signal=56% AUTODEGRADATION OF CDH1 BY CDH1:APC C%REACTOME%R-HSA-174084.2 AUTODEGRADATION OF CDH1 BY CDH1:APC C%REACTOME%R-HSA-174084.2 62 -0.7293011 -2.402039 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=60% G1 S DNA DAMAGE CHECKPOINTS%REACTOME%R-HSA-69615.2 G1 S DNA DAMAGE CHECKPOINTS%REACTOME%R-HSA-69615.2 66 -0.716867 -2.4003422 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=60% CELLULAR RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0071346 CELLULAR RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0071346 97 -0.6765954 -2.3978176 0.0 0.0 0.0 1186 tags=41%, list=8%, signal=44% REGULATION OF CELLULAR AMINE METABOLIC PROCESS%GOBP%GO:0033238 REGULATION OF CELLULAR AMINE METABOLIC PROCESS%GOBP%GO:0033238 56 -0.7459638 -2.3915672 0.0 0.0 0.0 2166 tags=55%, list=14%, signal=64% POSITIVE REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051443 POSITIVE REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051443 96 -0.67719114 -2.3875868 0.0 0.0 0.0 3357 tags=55%, list=22%, signal=70% THE CITRIC ACID (TCA) CYCLE AND RESPIRATORY ELECTRON TRANSPORT%REACTOME DATABASE ID RELEASE 60%1428517 THE CITRIC ACID (TCA) CYCLE AND RESPIRATORY ELECTRON TRANSPORT%REACTOME DATABASE ID RELEASE 60%1428517 143 -0.64485425 -2.3826022 0.0 0.0 0.0 3099 tags=58%, list=20%, signal=72% MITOTIC G1-G1 S PHASES%REACTOME DATABASE ID RELEASE 60%453279 MITOTIC G1-G1 S PHASES%REACTOME DATABASE ID RELEASE 60%453279 138 -0.6339328 -2.3795505 0.0 0.0 0.0 2988 tags=56%, list=20%, signal=69% CHROMOSOME MAINTENANCE%REACTOME DATABASE ID RELEASE 60%73886 CHROMOSOME MAINTENANCE%REACTOME DATABASE ID RELEASE 60%73886 82 -0.685061 -2.3725183 0.0 0.0 0.0 3664 tags=68%, list=24%, signal=89% T CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050852 T CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050852 129 -0.6471041 -2.3716767 0.0 0.0 0.0 2310 tags=50%, list=15%, signal=58% P53-DEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69580 P53-DEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69580 64 -0.7158939 -2.3670626 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=60% STABILIZATION OF P53%REACTOME DATABASE ID RELEASE 60%69541 STABILIZATION OF P53%REACTOME DATABASE ID RELEASE 60%69541 55 -0.73402286 -2.361894 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% VIF-MEDIATED DEGRADATION OF APOBEC3G%REACTOME DATABASE ID RELEASE 60%180585 VIF-MEDIATED DEGRADATION OF APOBEC3G%REACTOME DATABASE ID RELEASE 60%180585 51 -0.74453217 -2.36096 0.0 0.0 0.0 2988 tags=69%, list=20%, signal=85% SCF-BETA-TRCP MEDIATED DEGRADATION OF EMI1%REACTOME DATABASE ID RELEASE 60%174113 SCF-BETA-TRCP MEDIATED DEGRADATION OF EMI1%REACTOME DATABASE ID RELEASE 60%174113 53 -0.73214644 -2.3581274 0.0 0.0 0.0 2247 tags=55%, list=15%, signal=64% MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY%GOBP%GO:0033108 MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY%GOBP%GO:0033108 64 -0.7201863 -2.3575118 0.0 0.0 0.0 3272 tags=75%, list=22%, signal=95% ANTIGEN RECEPTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0050851 ANTIGEN RECEPTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0050851 150 -0.63333595 -2.3534296 0.0 0.0 0.0 2310 tags=49%, list=15%, signal=58% REGULATION OF APOPTOSIS%REACTOME%R-HSA-169911.2 REGULATION OF APOPTOSIS%REACTOME%R-HSA-169911.2 51 -0.73971164 -2.3529718 0.0 0.0 0.0 2247 tags=55%, list=15%, signal=64% NEGATIVE REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051444 NEGATIVE REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051444 82 -0.6821279 -2.3521314 0.0 0.0 0.0 2247 tags=49%, list=15%, signal=57% REGULATION OF CELLULAR AMINO ACID METABOLIC PROCESS%GOBP%GO:0006521 REGULATION OF CELLULAR AMINO ACID METABOLIC PROCESS%GOBP%GO:0006521 52 -0.7458599 -2.351062 0.0 0.0 0.0 2166 tags=56%, list=14%, signal=65% UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25A%REACTOME%R-HSA-69601.2 UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25A%REACTOME%R-HSA-69601.2 51 -0.73817956 -2.3509626 0.0 0.0 0.0 2247 tags=57%, list=15%, signal=66% P53-DEPENDENT G1 DNA DAMAGE RESPONSE%REACTOME%R-HSA-69563.3 P53-DEPENDENT G1 DNA DAMAGE RESPONSE%REACTOME%R-HSA-69563.3 64 -0.7158939 -2.3451502 0.0 0.0 0.0 2247 tags=52%, list=15%, signal=60% P53-INDEPENDENT DNA DAMAGE RESPONSE%REACTOME%R-HSA-69610.2 P53-INDEPENDENT DNA DAMAGE RESPONSE%REACTOME%R-HSA-69610.2 51 -0.73817956 -2.3429706 0.0 0.0 0.0 2247 tags=57%, list=15%, signal=66% ABC TRANSPORTER DISORDERS%REACTOME%R-HSA-5619084.4 ABC TRANSPORTER DISORDERS%REACTOME%R-HSA-5619084.4 62 -0.718732 -2.3427274 0.0 0.0 0.0 2275 tags=48%, list=15%, signal=57% MITOTIC PROMETAPHASE%REACTOME%R-HSA-68877.2 MITOTIC PROMETAPHASE%REACTOME%R-HSA-68877.2 101 -0.6358884 -2.3391593 0.0 0.0 0.0 3318 tags=53%, list=22%, signal=68% REGULATION OF ORNITHINE DECARBOXYLASE (ODC)%REACTOME%R-HSA-350562.1 REGULATION OF ORNITHINE DECARBOXYLASE (ODC)%REACTOME%R-HSA-350562.1 49 -0.7586659 -2.3391097 0.0 0.0 0.0 2166 tags=59%, list=14%, signal=69% MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY%GOBP%GO:0032981 MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY%GOBP%GO:0032981 50 -0.7330049 -2.3381653 0.0 0.0 0.0 3272 tags=80%, list=22%, signal=102% P53-INDEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME%R-HSA-69613.2 P53-INDEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME%R-HSA-69613.2 51 -0.73817956 -2.335822 0.0 0.0 0.0 2247 tags=57%, list=15%, signal=66% OXIDATIVE PHOSPHORYLATION%GOBP%GO:0006119 OXIDATIVE PHOSPHORYLATION%GOBP%GO:0006119 72 -0.7112595 -2.3350067 0.0 0.0 0.0 3066 tags=72%, list=20%, signal=90% HOST INTERACTIONS OF HIV FACTORS%REACTOME%R-HSA-162909.1 HOST INTERACTIONS OF HIV FACTORS%REACTOME%R-HSA-162909.1 121 -0.6296081 -2.3258572 0.0 0.0 0.0 4325 tags=64%, list=28%, signal=88% DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS%REACTOME%R-HSA-5678895.2 DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS%REACTOME%R-HSA-5678895.2 59 -0.72404253 -2.324449 0.0 0.0 0.0 3204 tags=61%, list=21%, signal=77% CYCLIN A:CDK2-ASSOCIATED EVENTS AT S PHASE ENTRY%REACTOME DATABASE ID RELEASE 60%69656 CYCLIN A:CDK2-ASSOCIATED EVENTS AT S PHASE ENTRY%REACTOME DATABASE ID RELEASE 60%69656 81 -0.6702573 -2.322639 0.0 0.0 0.0 2988 tags=54%, list=20%, signal=67% THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT%REACTOME%R-HSA-8852276.2 THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT%REACTOME%R-HSA-8852276.2 58 -0.72895515 -2.3194413 0.0 0.0 0.0 1584 tags=48%, list=10%, signal=54% FCERI MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-2871837.2 FCERI MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-2871837.2 76 -0.68023354 -2.3158946 0.0 0.0 0.0 2988 tags=53%, list=20%, signal=65% HH MUTANTS THAT DON'T UNDERGO AUTOCATALYTIC PROCESSING ARE DEGRADED BY ERAD%REACTOME DATABASE ID RELEASE 60%5362768 HH MUTANTS THAT DON'T UNDERGO AUTOCATALYTIC PROCESSING ARE DEGRADED BY ERAD%REACTOME DATABASE ID RELEASE 60%5362768 53 -0.7320892 -2.314833 0.0 0.0 0.0 3204 tags=66%, list=21%, signal=83% DEFENSE RESPONSE TO VIRUS%GOBP%GO:0051607 DEFENSE RESPONSE TO VIRUS%GOBP%GO:0051607 62 -0.717314 -2.31308 0.0 0.0 0.0 1272 tags=44%, list=8%, signal=47% REGULATION OF ACTIVATED PAK-2P34 BY PROTEASOME MEDIATED DEGRADATION%REACTOME DATABASE ID RELEASE 60%211733 REGULATION OF ACTIVATED PAK-2P34 BY PROTEASOME MEDIATED DEGRADATION%REACTOME DATABASE ID RELEASE 60%211733 48 -0.74121255 -2.3117354 0.0 0.0 0.0 2247 tags=56%, list=15%, signal=66% NEGATIVE REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045071 NEGATIVE REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045071 45 -0.74835265 -2.3113086 0.0 0.0 0.0 1637 tags=51%, list=11%, signal=57% RESPIRATORY ELECTRON TRANSPORT CHAIN%GOBP%GO:0022904 RESPIRATORY ELECTRON TRANSPORT CHAIN%GOBP%GO:0022904 77 -0.67597073 -2.3088744 0.0 0.0 0.0 3066 tags=68%, list=20%, signal=84% MITOCHONDRIAL ATP SYNTHESIS COUPLED ELECTRON TRANSPORT%GOBP%GO:0042775 MITOCHONDRIAL ATP SYNTHESIS COUPLED ELECTRON TRANSPORT%GOBP%GO:0042775 67 -0.70179164 -2.3085284 0.0 0.0 0.0 3066 tags=70%, list=20%, signal=87% HH MUTANTS ABROGATE LIGAND SECRETION%REACTOME DATABASE ID RELEASE 60%5387390 HH MUTANTS ABROGATE LIGAND SECRETION%REACTOME DATABASE ID RELEASE 60%5387390 53 -0.7320892 -2.3061664 0.0 0.0 0.0 3204 tags=66%, list=21%, signal=83% REGULATION OF RUNX3 EXPRESSION AND ACTIVITY%REACTOME%R-HSA-8941858.1 REGULATION OF RUNX3 EXPRESSION AND ACTIVITY%REACTOME%R-HSA-8941858.1 55 -0.71467453 -2.3060691 0.0 0.0 0.0 2247 tags=51%, list=15%, signal=60% NADH DEHYDROGENASE COMPLEX ASSEMBLY%GOBP%GO:0010257 NADH DEHYDROGENASE COMPLEX ASSEMBLY%GOBP%GO:0010257 50 -0.7330049 -2.3050375 0.0 0.0 0.0 3272 tags=80%, list=22%, signal=102% VPU MEDIATED DEGRADATION OF CD4%REACTOME DATABASE ID RELEASE 60%180534 VPU MEDIATED DEGRADATION OF CD4%REACTOME DATABASE ID RELEASE 60%180534 50 -0.73004586 -2.304727 0.0 0.0 0.0 2988 tags=66%, list=20%, signal=82% RIBONUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009199 RIBONUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009199 149 -0.6012484 -2.3033416 0.0 0.0 0.0 3066 tags=50%, list=20%, signal=62% AUF1 (HNRNP D0) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450408.3 AUF1 (HNRNP D0) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450408.3 51 -0.73220915 -2.302032 0.0 0.0 0.0 2247 tags=53%, list=15%, signal=62% DISORDERS OF TRANSMEMBRANE TRANSPORTERS%REACTOME%R-HSA-5619115.2 DISORDERS OF TRANSMEMBRANE TRANSPORTERS%REACTOME%R-HSA-5619115.2 65 -0.6887429 -2.3015432 0.0 0.0 0.0 2275 tags=46%, list=15%, signal=54% CDT1 ASSOCIATION WITH THE CDC6:ORC:ORIGIN COMPLEX%REACTOME DATABASE ID RELEASE 60%68827 CDT1 ASSOCIATION WITH THE CDC6:ORC:ORIGIN COMPLEX%REACTOME DATABASE ID RELEASE 60%68827 51 -0.7391182 -2.3009765 0.0 0.0 0.0 2247 tags=57%, list=15%, signal=66% CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION%REACTOME DATABASE ID RELEASE 60%69202 CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION%REACTOME DATABASE ID RELEASE 60%69202 82 -0.65883106 -2.300013 0.0 0.0 0.0 2988 tags=54%, list=20%, signal=66% ELECTRON TRANSPORT CHAIN%GOBP%GO:0022900 ELECTRON TRANSPORT CHAIN%GOBP%GO:0022900 78 -0.67214286 -2.299794 0.0 0.0 0.0 3066 tags=67%, list=20%, signal=83% SCF(SKP2)-MEDIATED DEGRADATION OF P27 P21%REACTOME%R-HSA-187577.3 SCF(SKP2)-MEDIATED DEGRADATION OF P27 P21%REACTOME%R-HSA-187577.3 60 -0.694952 -2.2936041 0.0 0.0 0.0 2247 tags=55%, list=15%, signal=64% ANTIGEN PROCESSING-CROSS PRESENTATION%REACTOME DATABASE ID RELEASE 60%1236975 ANTIGEN PROCESSING-CROSS PRESENTATION%REACTOME DATABASE ID RELEASE 60%1236975 94 -0.660175 -2.2934654 0.0 0.0 0.0 1916 tags=46%, list=13%, signal=52% PURINE NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009144 PURINE NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009144 153 -0.59945595 -2.2931924 0.0 0.0 0.0 3687 tags=56%, list=24%, signal=73% DECTIN-1 MEDIATED NONCANONICAL NF-KB SIGNALING%REACTOME DATABASE ID RELEASE 60%5607761 DECTIN-1 MEDIATED NONCANONICAL NF-KB SIGNALING%REACTOME DATABASE ID RELEASE 60%5607761 57 -0.7129894 -2.286287 0.0 1.19545875E-5 0.001 2247 tags=49%, list=15%, signal=57% DEGRADATION OF AXIN%REACTOME DATABASE ID RELEASE 60%4641257 DEGRADATION OF AXIN%REACTOME DATABASE ID RELEASE 60%4641257 53 -0.7233508 -2.2852526 0.0 1.1858179E-5 0.001 2247 tags=51%, list=15%, signal=60% REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU-RICH ELEMENTS%REACTOME%R-HSA-450531.4 REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU-RICH ELEMENTS%REACTOME%R-HSA-450531.4 82 -0.66227245 -2.283493 0.0 1.1763314E-5 0.001 3337 tags=52%, list=22%, signal=67% ATP SYNTHESIS COUPLED ELECTRON TRANSPORT%GOBP%GO:0042773 ATP SYNTHESIS COUPLED ELECTRON TRANSPORT%GOBP%GO:0042773 67 -0.70179164 -2.2809217 0.0 1.1669955E-5 0.001 3066 tags=70%, list=20%, signal=87% COMPLEX I BIOGENESIS%REACTOME%R-HSA-6799198.1 COMPLEX I BIOGENESIS%REACTOME%R-HSA-6799198.1 45 -0.7358366 -2.274848 0.0 1.1578065E-5 0.001 3616 tags=84%, list=24%, signal=110% ACTIVATION OF NF-KAPPAB IN B CELLS%REACTOME%R-HSA-1169091.1 ACTIVATION OF NF-KAPPAB IN B CELLS%REACTOME%R-HSA-1169091.1 65 -0.7027647 -2.274781 0.0 1.1487611E-5 0.001 2988 tags=58%, list=20%, signal=72% NIK-->NONCANONICAL NF-KB SIGNALING%REACTOME DATABASE ID RELEASE 60%5676590 NIK-->NONCANONICAL NF-KB SIGNALING%REACTOME DATABASE ID RELEASE 60%5676590 56 -0.70935076 -2.27235 0.0 1.139856E-5 0.001 2247 tags=48%, list=15%, signal=56% HALLMARK_ALLOGRAFT_REJECTION%MSIGDB_C2%HALLMARK_ALLOGRAFT_REJECTION HALLMARK_ALLOGRAFT_REJECTION%MSIGDB_C2%HALLMARK_ALLOGRAFT_REJECTION 183 -0.59336364 -2.2714865 0.0 1.1310879E-5 0.001 1954 tags=45%, list=13%, signal=51% MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I BIOGENESIS%GOBP%GO:0097031 MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I BIOGENESIS%GOBP%GO:0097031 50 -0.7330049 -2.2696908 0.0 1.1224536E-5 0.001 3272 tags=80%, list=22%, signal=102% TUMOR NECROSIS FACTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0033209 TUMOR NECROSIS FACTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0033209 105 -0.63779706 -2.2661738 0.0 1.1139502E-5 0.001 2247 tags=43%, list=15%, signal=50% REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051438 REGULATION OF UBIQUITIN-PROTEIN TRANSFERASE ACTIVITY%GOBP%GO:0051438 114 -0.61913085 -2.2654266 0.0 1.1055746E-5 0.001 3357 tags=48%, list=22%, signal=61% MITOCHONDRIAL ELECTRON TRANSPORT, NADH TO UBIQUINONE%GOBP%GO:0006120 MITOCHONDRIAL ELECTRON TRANSPORT, NADH TO UBIQUINONE%GOBP%GO:0006120 39 -0.75841916 -2.265415 0.0 1.097324E-5 0.001 3251 tags=85%, list=21%, signal=107% NIK/NF-KAPPAB SIGNALING%GOBP%GO:0038061 NIK/NF-KAPPAB SIGNALING%GOBP%GO:0038061 77 -0.6700135 -2.2617786 0.0 1.0891957E-5 0.001 2247 tags=40%, list=15%, signal=47% ATP METABOLIC PROCESS%GOBP%GO:0046034 ATP METABOLIC PROCESS%GOBP%GO:0046034 135 -0.6074696 -2.260934 0.0 1.0811869E-5 0.001 3651 tags=59%, list=24%, signal=76% REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032479 REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032479 102 -0.6470586 -2.260884 0.0 1.0732951E-5 0.001 2878 tags=41%, list=19%, signal=50% CDK-MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6%REACTOME%R-HSA-69017.2 CDK-MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6%REACTOME%R-HSA-69017.2 49 -0.7374656 -2.2604945 0.0 1.0655175E-5 0.001 2247 tags=57%, list=15%, signal=67% SISTER CHROMATID SEGREGATION%GOBP%GO:0000819 SISTER CHROMATID SEGREGATION%GOBP%GO:0000819 157 -0.5933107 -2.259541 0.0 1.0578519E-5 0.001 3348 tags=49%, list=22%, signal=62% PURINE RIBONUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009205 PURINE RIBONUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009205 149 -0.6012484 -2.2533736 0.0 1.05029585E-5 0.001 3066 tags=50%, list=20%, signal=62% AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1%REACTOME%R-HSA-349425.2 AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1%REACTOME%R-HSA-349425.2 50 -0.73021126 -2.252905 0.0 1.0428469E-5 0.001 2247 tags=54%, list=15%, signal=63% RESOLUTION OF SISTER CHROMATID COHESION%REACTOME DATABASE ID RELEASE 60%2500257 RESOLUTION OF SISTER CHROMATID COHESION%REACTOME DATABASE ID RELEASE 60%2500257 93 -0.6386675 -2.2520688 0.0 1.0355029E-5 0.001 3318 tags=54%, list=22%, signal=68% CELLULAR RESPIRATION%GOBP%GO:0045333 CELLULAR RESPIRATION%GOBP%GO:0045333 117 -0.61083037 -2.24616 0.0 1.0282616E-5 0.001 3066 tags=60%, list=20%, signal=74% OXYGEN-DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA-INDUCIBLE FACTOR ALPHA%REACTOME DATABASE ID RELEASE 60%1234176 OXYGEN-DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA-INDUCIBLE FACTOR ALPHA%REACTOME DATABASE ID RELEASE 60%1234176 63 -0.68461055 -2.2353525 0.0 1.021121E-5 0.001 2988 tags=57%, list=20%, signal=71% UB-SPECIFIC PROCESSING PROTEASES%REACTOME DATABASE ID RELEASE 60%5689880 UB-SPECIFIC PROCESSING PROTEASES%REACTOME DATABASE ID RELEASE 60%5689880 175 -0.5745591 -2.230596 0.0 1.0140788E-5 0.001 3337 tags=40%, list=22%, signal=51% REGULATION OF HYPOXIA-INDUCIBLE FACTOR (HIF) BY OXYGEN%REACTOME%R-HSA-1234174.1 REGULATION OF HYPOXIA-INDUCIBLE FACTOR (HIF) BY OXYGEN%REACTOME%R-HSA-1234174.1 71 -0.66684014 -2.2282207 0.0 1.00713305E-5 0.001 2988 tags=51%, list=20%, signal=63% REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA%GOBP%GO:0061418 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA%GOBP%GO:0061418 75 -0.65290254 -2.2211878 0.0 1.0002818E-5 0.001 2988 tags=49%, list=20%, signal=61% PRE-MRNA SPLICING%REACTOME DATABASE ID RELEASE 60%72163 PRE-MRNA SPLICING%REACTOME DATABASE ID RELEASE 60%72163 163 -0.5790559 -2.2193537 0.0 9.935231E-6 0.001 3791 tags=45%, list=25%, signal=59% TNFR2 NON-CANONICAL NF-KB PATHWAY%REACTOME DATABASE ID RELEASE 60%5668541 TNFR2 NON-CANONICAL NF-KB PATHWAY%REACTOME DATABASE ID RELEASE 60%5668541 93 -0.6169289 -2.2186599 0.0 9.868552E-6 0.001 1659 tags=34%, list=11%, signal=38% CELLULAR RESPONSE TO HYPOXIA%REACTOME%R-HSA-2262749.1 CELLULAR RESPONSE TO HYPOXIA%REACTOME%R-HSA-2262749.1 71 -0.66684014 -2.2179995 0.0 9.802761E-6 0.001 2988 tags=51%, list=20%, signal=63% NEGATIVE REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903901 NEGATIVE REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903901 61 -0.6908023 -2.2134564 0.0 9.737842E-6 0.001 1637 tags=41%, list=11%, signal=46% NEGATIVE REGULATION OF VIRAL PROCESS%GOBP%GO:0048525 NEGATIVE REGULATION OF VIRAL PROCESS%GOBP%GO:0048525 74 -0.654467 -2.2074785 0.0 9.673778E-6 0.001 1988 tags=39%, list=13%, signal=45% CLEC7A (DECTIN-1) SIGNALING%REACTOME DATABASE ID RELEASE 60%5607764 CLEC7A (DECTIN-1) SIGNALING%REACTOME DATABASE ID RELEASE 60%5607764 96 -0.6145655 -2.2054105 0.0 9.6105505E-6 0.001 2988 tags=44%, list=20%, signal=54% DEGRADATION OF GLI1 BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610780 DEGRADATION OF GLI1 BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610780 57 -0.68232596 -2.2019885 0.0 9.548145E-6 0.001 2247 tags=49%, list=15%, signal=57% SISTER CHROMATID COHESION%GOBP%GO:0007062 SISTER CHROMATID COHESION%GOBP%GO:0007062 99 -0.62545526 -2.1999087 0.0 9.486544E-6 0.001 3318 tags=53%, list=22%, signal=67% POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032481 POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032481 61 -0.6732751 -2.1964304 0.0 9.425732E-6 0.001 2857 tags=46%, list=19%, signal=56% HEDGEHOG LIGAND BIOGENESIS%REACTOME%R-HSA-5358346.1 HEDGEHOG LIGAND BIOGENESIS%REACTOME%R-HSA-5358346.1 60 -0.67666227 -2.1916325 0.0 9.365695E-6 0.001 2265 tags=47%, list=15%, signal=55% MRNA SPLICING%REACTOME DATABASE ID RELEASE 60%72172 MRNA SPLICING%REACTOME DATABASE ID RELEASE 60%72172 171 -0.5796906 -2.170916 0.0 9.306419E-6 0.001 3791 tags=45%, list=25%, signal=59% UBIQUITIN-DEPENDENT DEGRADATION OF CYCLIN D%REACTOME%R-HSA-75815.2 UBIQUITIN-DEPENDENT DEGRADATION OF CYCLIN D%REACTOME%R-HSA-75815.2 49 -0.70794696 -2.1691425 0.0 9.247888E-6 0.001 2247 tags=57%, list=15%, signal=67% UBIQUITIN-DEPENDENT DEGRADATION OF CYCLIN D1%REACTOME DATABASE ID RELEASE 60%69229 UBIQUITIN-DEPENDENT DEGRADATION OF CYCLIN D1%REACTOME DATABASE ID RELEASE 60%69229 49 -0.70794696 -2.1673744 0.0 9.190088E-6 0.001 2247 tags=57%, list=15%, signal=67% HALLMARK_MYC_TARGETS_V2%MSIGDB_C2%HALLMARK_MYC_TARGETS_V2 HALLMARK_MYC_TARGETS_V2%MSIGDB_C2%HALLMARK_MYC_TARGETS_V2 58 -0.66011477 -2.1663175 0.0 9.133008E-6 0.001 4246 tags=71%, list=28%, signal=98% NUCLEOSOME ASSEMBLY%REACTOME%R-HSA-774815.1 NUCLEOSOME ASSEMBLY%REACTOME%R-HSA-774815.1 47 -0.6837583 -2.1609654 0.0 9.076631E-6 0.001 3664 tags=68%, list=24%, signal=89% TELOMERE MAINTENANCE%REACTOME DATABASE ID RELEASE 60%157579 TELOMERE MAINTENANCE%REACTOME DATABASE ID RELEASE 60%157579 59 -0.67104757 -2.1574583 0.0 9.020947E-6 0.001 3655 tags=66%, list=24%, signal=87% NEGATIVE REGULATION OF PROTEIN UBIQUITINATION%GOBP%GO:0031397 NEGATIVE REGULATION OF PROTEIN UBIQUITINATION%GOBP%GO:0031397 118 -0.5959037 -2.1543064 0.0 8.965941E-6 0.001 2247 tags=38%, list=15%, signal=44% FBXL7 DOWN-REGULATES AURKA DURING MITOTIC ENTRY AND IN EARLY MITOSIS%REACTOME%R-HSA-8854050.2 FBXL7 DOWN-REGULATES AURKA DURING MITOTIC ENTRY AND IN EARLY MITOSIS%REACTOME%R-HSA-8854050.2 53 -0.66607034 -2.1475596 0.0 8.911602E-6 0.001 2247 tags=53%, list=15%, signal=62% DNA REPLICATION%GOBP%GO:0006260 DNA REPLICATION%GOBP%GO:0006260 150 -0.56763387 -2.1437392 0.0 8.857917E-6 0.001 2808 tags=41%, list=18%, signal=50% DEGRADATION OF GLI2 BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610783 DEGRADATION OF GLI2 BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610783 57 -0.6773252 -2.1430566 0.0 1.7816375E-5 0.002 2247 tags=49%, list=15%, signal=57% DEFENSE RESPONSE TO OTHER ORGANISM%GOBP%GO:0098542 DEFENSE RESPONSE TO OTHER ORGANISM%GOBP%GO:0098542 132 -0.57447344 -2.140412 0.0 1.7710325E-5 0.002 2195 tags=39%, list=14%, signal=45% NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL%GOBP%GO:1903321 NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL%GOBP%GO:1903321 122 -0.59481573 -2.1370647 0.0 2.6025942E-5 0.003 2247 tags=38%, list=15%, signal=44% RRNA PROCESSING%REACTOME%R-HSA-72312.3 RRNA PROCESSING%REACTOME%R-HSA-72312.3 191 -0.54926807 -2.1364589 0.0 2.5872847E-5 0.003 4515 tags=53%, list=30%, signal=74% TRNA METABOLIC PROCESS%GOBP%GO:0006399 TRNA METABOLIC PROCESS%GOBP%GO:0006399 128 -0.5765447 -2.131544 0.0 3.404347E-5 0.004 4444 tags=55%, list=29%, signal=78% RESPONSE TO VIRUS%GOBP%GO:0009615 RESPONSE TO VIRUS%GOBP%GO:0009615 144 -0.57143897 -2.1239283 0.0 4.254241E-5 0.005 1365 tags=35%, list=9%, signal=39% MITOCHONDRIAL PROTEIN IMPORT%REACTOME DATABASE ID RELEASE 60%1268020 MITOCHONDRIAL PROTEIN IMPORT%REACTOME DATABASE ID RELEASE 60%1268020 54 -0.6568349 -2.1213975 0.0 4.2296502E-5 0.005 4225 tags=72%, list=28%, signal=100% NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009141 NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009141 165 -0.55314153 -2.121108 0.0 4.205342E-5 0.005 3687 tags=55%, list=24%, signal=71% DNA RECOMBINATION%GOBP%GO:0006310 DNA RECOMBINATION%GOBP%GO:0006310 133 -0.57399863 -2.1204731 0.0 4.1813113E-5 0.005 3573 tags=46%, list=23%, signal=59% DEPOSITION OF NEW CENPA-CONTAINING NUCLEOSOMES AT THE CENTROMERE%REACTOME%R-HSA-606279.1 DEPOSITION OF NEW CENPA-CONTAINING NUCLEOSOMES AT THE CENTROMERE%REACTOME%R-HSA-606279.1 47 -0.6837583 -2.1188424 0.0 5.013271E-5 0.006 3664 tags=68%, list=24%, signal=89% UCH PROTEINASES%REACTOME DATABASE ID RELEASE 60%5689603 UCH PROTEINASES%REACTOME DATABASE ID RELEASE 60%5689603 89 -0.59908634 -2.114478 0.0 5.8132387E-5 0.007 3035 tags=51%, list=20%, signal=63% MITOTIC G2-G2 M PHASES%REACTOME DATABASE ID RELEASE 60%453274 MITOTIC G2-G2 M PHASES%REACTOME DATABASE ID RELEASE 60%453274 168 -0.54938215 -2.1125245 0.0 5.7805802E-5 0.007 3379 tags=43%, list=22%, signal=54% G2 M TRANSITION%REACTOME%R-HSA-69275.4 G2 M TRANSITION%REACTOME%R-HSA-69275.4 166 -0.54798365 -2.1125007 0.0 5.7482863E-5 0.007 3379 tags=43%, list=22%, signal=54% GLI3 IS PROCESSED TO GLI3R BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610785 GLI3 IS PROCESSED TO GLI3R BY THE PROTEASOME%REACTOME DATABASE ID RELEASE 60%5610785 57 -0.63239974 -2.1039674 0.0 6.56202E-5 0.008 2247 tags=49%, list=15%, signal=57% BIOCARTA_PROTEASOME_PATHWAY%MSIGDB_C2%BIOCARTA_PROTEASOME_PATHWAY BIOCARTA_PROTEASOME_PATHWAY%MSIGDB_C2%BIOCARTA_PROTEASOME_PATHWAY 28 -0.770808 -2.1034343 0.0 6.5257664E-5 0.008 2849 tags=79%, list=19%, signal=97% ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002250 ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002250 70 -0.6271543 -2.1030314 0.0 6.4899104E-5 0.008 3105 tags=49%, list=20%, signal=61% NUCLEOSOME ASSEMBLY%GOBP%GO:0006334 NUCLEOSOME ASSEMBLY%GOBP%GO:0006334 71 -0.6203749 -2.1018279 0.0 6.454447E-5 0.008 3319 tags=52%, list=22%, signal=66% INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002220 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002220 104 -0.5848019 -2.0958216 0.0 6.4193686E-5 0.008 2988 tags=48%, list=20%, signal=59% REGULATION OF VIRAL PROCESS%GOBP%GO:0050792 REGULATION OF VIRAL PROCESS%GOBP%GO:0050792 161 -0.5596129 -2.0955598 0.0 6.384669E-5 0.008 2530 tags=35%, list=17%, signal=41% REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045069 REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045069 68 -0.6299502 -2.092101 0.0 6.350343E-5 0.008 1982 tags=41%, list=13%, signal=47% HALLMARK_G2M_CHECKPOINT%MSIGDB_C2%HALLMARK_G2M_CHECKPOINT HALLMARK_G2M_CHECKPOINT%MSIGDB_C2%HALLMARK_G2M_CHECKPOINT 190 -0.5506906 -2.0907464 0.0 6.316384E-5 0.008 2460 tags=41%, list=16%, signal=48% RRNA PROCESSING IN THE NUCLEUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 60%8868773 RRNA PROCESSING IN THE NUCLEUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 60%8868773 183 -0.5415541 -2.0825768 0.0 6.282786E-5 0.008 4515 tags=52%, list=30%, signal=73% BARD1 SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BARD1 SIGNALING EVENTS BARD1 SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BARD1 SIGNALING EVENTS 28 -0.7471016 -2.0778654 0.0 7.033338E-5 0.009 1787 tags=46%, list=12%, signal=53% PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043241 PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043241 142 -0.54477924 -2.0776258 0.0 6.996321E-5 0.009 3028 tags=56%, list=20%, signal=70% SCF-DEPENDENT PROTEASOMAL UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0031146 SCF-DEPENDENT PROTEASOMAL UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0031146 68 -0.6268703 -2.0766294 0.0 6.959691E-5 0.009 2247 tags=44%, list=15%, signal=52% NUCLEAR CHROMOSOME SEGREGATION%GOBP%GO:0098813 NUCLEAR CHROMOSOME SEGREGATION%GOBP%GO:0098813 179 -0.54428005 -2.0755773 0.0 6.923442E-5 0.009 3577 tags=49%, list=24%, signal=64% PD-1 SIGNALING%REACTOME DATABASE ID RELEASE 60%389948 PD-1 SIGNALING%REACTOME DATABASE ID RELEASE 60%389948 20 -0.8132677 -2.073637 0.0 6.887569E-5 0.009 1474 tags=75%, list=10%, signal=83% IL12-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL12-MEDIATED SIGNALING EVENTS IL12-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL12-MEDIATED SIGNALING EVENTS 54 -0.6527809 -2.0724483 0.0 6.852066E-5 0.009 1474 tags=46%, list=10%, signal=51% NEGATIVE REGULATION OF CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:1902750 NEGATIVE REGULATION OF CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:1902750 73 -0.62513155 -2.0695167 0.0 7.572103E-5 0.01 3079 tags=53%, list=20%, signal=67% INNER MITOCHONDRIAL MEMBRANE ORGANIZATION%GOBP%GO:0007007 INNER MITOCHONDRIAL MEMBRANE ORGANIZATION%GOBP%GO:0007007 31 -0.7195317 -2.0647612 0.0 9.063734E-5 0.012 2619 tags=71%, list=17%, signal=86% NUCLEOSOME ORGANIZATION%GOBP%GO:0034728 NUCLEOSOME ORGANIZATION%GOBP%GO:0034728 95 -0.5927658 -2.0642445 0.0 9.017725E-5 0.012 3746 tags=49%, list=25%, signal=65% PID_IL12_2PATHWAY%MSIGDB_C2%PID_IL12_2PATHWAY PID_IL12_2PATHWAY%MSIGDB_C2%PID_IL12_2PATHWAY 57 -0.634327 -2.0612385 0.0 9.702392E-5 0.013 1474 tags=44%, list=10%, signal=48% CROSS-PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS (ENDOSOMES)%REACTOME DATABASE ID RELEASE 60%1236978 CROSS-PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS (ENDOSOMES)%REACTOME DATABASE ID RELEASE 60%1236978 48 -0.65961695 -2.0608315 0.0 9.6536365E-5 0.013 2313 tags=58%, list=15%, signal=69% STIMULATORY C-TYPE LECTIN RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002223 STIMULATORY C-TYPE LECTIN RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002223 103 -0.5849221 -2.0593832 0.0 9.605368E-5 0.013 2988 tags=49%, list=20%, signal=60% DNA PACKAGING%GOBP%GO:0006323 DNA PACKAGING%GOBP%GO:0006323 106 -0.58504504 -2.059106 0.0 1.0296234E-4 0.014 3348 tags=48%, list=22%, signal=61% DEGRADATION OF BETA-CATENIN BY THE DESTRUCTION COMPLEX%REACTOME%R-HSA-195253.1 DEGRADATION OF BETA-CATENIN BY THE DESTRUCTION COMPLEX%REACTOME%R-HSA-195253.1 79 -0.6075639 -2.05874 0.0 1.0245262E-4 0.014 2252 tags=38%, list=15%, signal=44% TRNA PROCESSING%REACTOME%R-HSA-72306.5 TRNA PROCESSING%REACTOME%R-HSA-72306.5 92 -0.5867805 -2.0572822 0.0 1.0194793E-4 0.014 4293 tags=57%, list=28%, signal=78% REGULATION OF G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0010389 REGULATION OF G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0010389 90 -0.57662773 -2.0553012 0.0 1.0144818E-4 0.014 3337 tags=53%, list=22%, signal=68% DNA STRAND ELONGATION%REACTOME%R-HSA-69190.2 DNA STRAND ELONGATION%REACTOME%R-HSA-69190.2 32 -0.7294768 -2.0533626 0.0 1.00953315E-4 0.014 3042 tags=75%, list=20%, signal=94% REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903900 REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903900 109 -0.5664761 -2.0516882 0.0 1.0046325E-4 0.014 1272 tags=28%, list=8%, signal=30% PID_BARD1_PATHWAY%MSIGDB_C2%PID_BARD1_PATHWAY PID_BARD1_PATHWAY%MSIGDB_C2%PID_BARD1_PATHWAY 29 -0.74195856 -2.0489082 0.0 9.9977915E-5 0.014 1787 tags=45%, list=12%, signal=51% MITOTIC RECOMBINATION%GOBP%GO:0006312 MITOTIC RECOMBINATION%GOBP%GO:0006312 41 -0.67489785 -2.0439794 0.0 1.20752695E-4 0.017 3042 tags=56%, list=20%, signal=70% NEGATIVE REGULATION OF G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0010972 NEGATIVE REGULATION OF G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0010972 71 -0.62443614 -2.0419207 0.0 1.2017493E-4 0.017 2247 tags=44%, list=15%, signal=51% POSITIVE REGULATION OF PROTEIN UBIQUITINATION%GOBP%GO:0031398 POSITIVE REGULATION OF PROTEIN UBIQUITINATION%GOBP%GO:0031398 153 -0.5319367 -2.0393476 0.0 1.266411E-4 0.018 2310 tags=35%, list=15%, signal=41% ANTIGEN PRESENTATION: FOLDING, ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC%REACTOME%R-HSA-983170.3 ANTIGEN PRESENTATION: FOLDING, ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC%REACTOME%R-HSA-983170.3 24 -0.7553359 -2.0393307 0.0 1.260409E-4 0.018 229 tags=38%, list=2%, signal=38% LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002449 LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002449 50 -0.65325254 -2.0386062 0.0 1.2544637E-4 0.018 2195 tags=42%, list=14%, signal=49% TELOMERE MAINTENANCE%GOBP%GO:0000723 TELOMERE MAINTENANCE%GOBP%GO:0000723 76 -0.6160318 -2.0354364 0.0 1.2485741E-4 0.018 3655 tags=51%, list=24%, signal=67% DNA-DEPENDENT DNA REPLICATION%GOBP%GO:0006261 DNA-DEPENDENT DNA REPLICATION%GOBP%GO:0006261 80 -0.6026344 -2.0329423 0.0 1.3112478E-4 0.019 3539 tags=51%, list=23%, signal=66% DNA BIOSYNTHETIC PROCESS%GOBP%GO:0071897 DNA BIOSYNTHETIC PROCESS%GOBP%GO:0071897 83 -0.5880317 -2.03134 0.0 1.3751983E-4 0.02 3584 tags=48%, list=24%, signal=63% REGULATION OF DEFENSE RESPONSE TO VIRUS%GOBP%GO:0050688 REGULATION OF DEFENSE RESPONSE TO VIRUS%GOBP%GO:0050688 42 -0.6896599 -2.0308397 0.0 1.4364562E-4 0.021 1236 tags=29%, list=8%, signal=31% MAJOR PATHWAY OF RRNA PROCESSING IN THE NUCLEOLUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 60%6791226 MAJOR PATHWAY OF RRNA PROCESSING IN THE NUCLEOLUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 60%6791226 175 -0.53359175 -2.0269935 0.0 1.4298366E-4 0.021 4515 tags=51%, list=30%, signal=71% CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002753 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002753 29 -0.7284664 -2.0234911 0.0 1.5614033E-4 0.023 2310 tags=45%, list=15%, signal=53% CENTROMERE COMPLEX ASSEMBLY%GOBP%GO:0034508 CENTROMERE COMPLEX ASSEMBLY%GOBP%GO:0034508 36 -0.6874159 -2.0226676 0.0 1.6248618E-4 0.024 3664 tags=67%, list=24%, signal=88% NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009123 NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009123 164 -0.537138 -2.0195248 0.0 1.8129402E-4 0.027 3066 tags=48%, list=20%, signal=59% ACTIVATION OF INNATE IMMUNE RESPONSE%GOBP%GO:0002218 ACTIVATION OF INNATE IMMUNE RESPONSE%GOBP%GO:0002218 191 -0.5141648 -2.0191326 0.0 1.8710751E-4 0.028 2909 tags=39%, list=19%, signal=47% TELOMERE MAINTENANCE VIA RECOMBINATION%GOBP%GO:0000722 TELOMERE MAINTENANCE VIA RECOMBINATION%GOBP%GO:0000722 32 -0.6971458 -2.0185177 0.0 1.8626467E-4 0.028 3042 tags=59%, list=20%, signal=74% HISTONE EXCHANGE%GOBP%GO:0043486 HISTONE EXCHANGE%GOBP%GO:0043486 37 -0.6972891 -2.0183308 0.0 1.8542941E-4 0.028 3680 tags=70%, list=24%, signal=92% PURINE NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009126 PURINE NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009126 161 -0.52923626 -2.0174403 0.0 1.9139197E-4 0.029 3066 tags=47%, list=20%, signal=58% PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS%REACTOME DATABASE ID RELEASE 60%202427 PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS%REACTOME DATABASE ID RELEASE 60%202427 19 -0.790559 -2.0164094 0.0 2.0354378E-4 0.031 2309 tags=74%, list=15%, signal=87% RIBONUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009161 RIBONUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009161 163 -0.53339154 -2.0108175 0.0 2.3565203E-4 0.036 3066 tags=47%, list=20%, signal=59% CHROMATIN ASSEMBLY%GOBP%GO:0031497 CHROMATIN ASSEMBLY%GOBP%GO:0031497 83 -0.5802959 -2.0087934 0.0 2.3461391E-4 0.036 3319 tags=48%, list=22%, signal=61% ACTIVATION OF THE PRE-REPLICATIVE COMPLEX%REACTOME DATABASE ID RELEASE 60%68962 ACTIVATION OF THE PRE-REPLICATIVE COMPLEX%REACTOME DATABASE ID RELEASE 60%68962 25 -0.73356265 -2.0075195 0.0 2.52862E-4 0.039 3539 tags=88%, list=23%, signal=114% PROTON TRANSPORT%GOBP%GO:0015992 PROTON TRANSPORT%GOBP%GO:0015992 44 -0.6597541 -2.0072124 0.0 2.517578E-4 0.039 2619 tags=50%, list=17%, signal=60% TELOMERE ORGANIZATION%GOBP%GO:0032200 TELOMERE ORGANIZATION%GOBP%GO:0032200 84 -0.5861794 -2.0066395 0.0 2.506632E-4 0.039 3655 tags=46%, list=24%, signal=61% TRANSLOCATION OF ZAP-70 TO IMMUNOLOGICAL SYNAPSE%REACTOME DATABASE ID RELEASE 60%202430 TRANSLOCATION OF ZAP-70 TO IMMUNOLOGICAL SYNAPSE%REACTOME DATABASE ID RELEASE 60%202430 16 -0.82608366 -2.0042164 0.0 2.559294E-4 0.04 2309 tags=94%, list=15%, signal=110% RESOLUTION OF ABASIC SITES (AP SITES)%REACTOME%R-HSA-73933.1 RESOLUTION OF ABASIC SITES (AP SITES)%REACTOME%R-HSA-73933.1 37 -0.68650347 -2.003704 0.0 2.5482624E-4 0.04 3152 tags=57%, list=21%, signal=71% TRNA PROCESSING%GOBP%GO:0008033 TRNA PROCESSING%GOBP%GO:0008033 77 -0.6001768 -2.0013964 0.0 2.5992427E-4 0.041 4122 tags=57%, list=27%, signal=78% UBIQUITIN PROTEASOME PATHWAY%PANTHER PATHWAY%P00060 UBIQUITIN PROTEASOME PATHWAY%PANTHER PATHWAY%P00060 43 -0.6625454 -1.9987471 0.0 2.6509733E-4 0.042 2310 tags=33%, list=15%, signal=38% DOUBLE-STRAND BREAK REPAIR%GOBP%GO:0006302 DOUBLE-STRAND BREAK REPAIR%GOBP%GO:0006302 130 -0.53776175 -1.9979912 0.0 2.6396927E-4 0.042 3792 tags=45%, list=25%, signal=60% MACROMOLECULAR COMPLEX DISASSEMBLY%GOBP%GO:0032984 MACROMOLECULAR COMPLEX DISASSEMBLY%GOBP%GO:0032984 171 -0.5239366 -1.9971371 0.0 2.6285075E-4 0.042 3028 tags=49%, list=20%, signal=61% MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0000070 MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0000070 82 -0.59405565 -1.9970479 0.0 2.6174166E-4 0.042 3642 tags=54%, list=24%, signal=70% C-TYPE LECTIN RECEPTORS (CLRS)%REACTOME DATABASE ID RELEASE 60%5621481 C-TYPE LECTIN RECEPTORS (CLRS)%REACTOME DATABASE ID RELEASE 60%5621481 122 -0.55391103 -1.9954457 0.0 2.6693655E-4 0.043 2988 tags=43%, list=20%, signal=53% ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002460 ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002460 56 -0.6156528 -1.9951532 0.0 2.6581966E-4 0.043 3105 tags=48%, list=20%, signal=60% REGULATION OF CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:1902749 REGULATION OF CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:1902749 96 -0.5767487 -1.994998 0.0 2.647121E-4 0.043 3379 tags=53%, list=22%, signal=68% U12 DEPENDENT SPLICING%REACTOME DATABASE ID RELEASE 60%72165 U12 DEPENDENT SPLICING%REACTOME DATABASE ID RELEASE 60%72165 47 -0.6491273 -1.99497 0.0 2.6361368E-4 0.043 2890 tags=51%, list=19%, signal=63% RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6790901.4 RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6790901.4 55 -0.6171396 -1.9946136 0.0 2.6252438E-4 0.043 4193 tags=62%, list=28%, signal=85% BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%73884 BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%73884 37 -0.68650347 -1.9928045 0.0 2.738212E-4 0.045 3152 tags=57%, list=21%, signal=71% CENP-A CONTAINING CHROMATIN ORGANIZATION%GOBP%GO:0061641 CENP-A CONTAINING CHROMATIN ORGANIZATION%GOBP%GO:0061641 30 -0.69550467 -1.9919713 0.0031152647 2.72699E-4 0.045 3664 tags=70%, list=24%, signal=92% PROTEIN-DNA COMPLEX SUBUNIT ORGANIZATION%GOBP%GO:0071824 PROTEIN-DNA COMPLEX SUBUNIT ORGANIZATION%GOBP%GO:0071824 151 -0.52794755 -1.9914993 0.0 2.7158592E-4 0.045 3782 tags=48%, list=25%, signal=63% TERMINATION OF RNA POLYMERASE II TRANSCRIPTION%GOBP%GO:0006369 TERMINATION OF RNA POLYMERASE II TRANSCRIPTION%GOBP%GO:0006369 55 -0.6150527 -1.9894173 0.0 2.7048192E-4 0.045 3885 tags=53%, list=26%, signal=71% PURINE RIBONUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009167 PURINE RIBONUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009167 161 -0.52923626 -1.9874554 0.0 2.8130866E-4 0.047 3066 tags=47%, list=20%, signal=58% INTERSTRAND CROSS-LINK REPAIR%GOBP%GO:0036297 INTERSTRAND CROSS-LINK REPAIR%GOBP%GO:0036297 39 -0.661198 -1.9863952 0.0 2.862518E-4 0.048 2567 tags=49%, list=17%, signal=58% HALLMARK_DNA_REPAIR%MSIGDB_C2%HALLMARK_DNA_REPAIR HALLMARK_DNA_REPAIR%MSIGDB_C2%HALLMARK_DNA_REPAIR 141 -0.5376519 -1.9858934 0.0 2.851022E-4 0.048 3658 tags=50%, list=24%, signal=65% REGULATION OF RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0060330 REGULATION OF RESPONSE TO INTERFERON-GAMMA%GOBP%GO:0060330 18 -0.7939648 -1.9836457 0.0 2.9582254E-4 0.05 512 tags=39%, list=3%, signal=40% DEGRADATION OF DVL%REACTOME DATABASE ID RELEASE 60%4641258 DEGRADATION OF DVL%REACTOME DATABASE ID RELEASE 60%4641258 55 -0.6186507 -1.9824452 0.0 3.0061253E-4 0.051 2247 tags=51%, list=15%, signal=60% HYDROGEN TRANSPORT%GOBP%GO:0006818 HYDROGEN TRANSPORT%GOBP%GO:0006818 46 -0.648091 -1.9808453 0.0 3.1673917E-4 0.054 2619 tags=48%, list=17%, signal=58% NEGATIVE REGULATORS OF RIG-I MDA5 SIGNALING%REACTOME%R-HSA-936440.1 NEGATIVE REGULATORS OF RIG-I MDA5 SIGNALING%REACTOME%R-HSA-936440.1 34 -0.6582482 -1.9807584 0.0 3.1548724E-4 0.054 2834 tags=41%, list=19%, signal=50% CHROMATIN REMODELING AT CENTROMERE%GOBP%GO:0031055 CHROMATIN REMODELING AT CENTROMERE%GOBP%GO:0031055 32 -0.69754255 -1.9800394 0.0 3.1424515E-4 0.054 3664 tags=69%, list=24%, signal=90% TRANSCRIPTION-COUPLED NUCLEOTIDE EXCISION REPAIR (TC-NER)%REACTOME%R-HSA-6781827.1 TRANSCRIPTION-COUPLED NUCLEOTIDE EXCISION REPAIR (TC-NER)%REACTOME%R-HSA-6781827.1 77 -0.57896686 -1.9780012 0.0 3.2446923E-4 0.056 3042 tags=42%, list=20%, signal=52% MITOTIC NUCLEAR DIVISION%GOBP%GO:0140014 MITOTIC NUCLEAR DIVISION%GOBP%GO:0140014 116 -0.5386979 -1.9771 0.0 3.2887424E-4 0.057 3642 tags=47%, list=24%, signal=62% RIG-I MDA5 MEDIATED INDUCTION OF IFN-ALPHA BETA PATHWAYS%REACTOME DATABASE ID RELEASE 60%168928 RIG-I MDA5 MEDIATED INDUCTION OF IFN-ALPHA BETA PATHWAYS%REACTOME DATABASE ID RELEASE 60%168928 67 -0.6163294 -1.9730731 0.0 3.7355674E-4 0.065 2857 tags=39%, list=19%, signal=48% ISG15 ANTIVIRAL MECHANISM%REACTOME%R-HSA-1169408.2 ISG15 ANTIVIRAL MECHANISM%REACTOME%R-HSA-1169408.2 66 -0.59492356 -1.96359 0.0 4.6974485E-4 0.082 1140 tags=27%, list=7%, signal=29% GENE SILENCING BY RNA%REACTOME DATABASE ID RELEASE 60%211000 GENE SILENCING BY RNA%REACTOME DATABASE ID RELEASE 60%211000 87 -0.5671223 -1.9621067 0.0 4.9103505E-4 0.086 4337 tags=55%, list=29%, signal=77% DUAL INCISION IN TC-NER%REACTOME%R-HSA-6782135.1 DUAL INCISION IN TC-NER%REACTOME%R-HSA-6782135.1 64 -0.5897047 -1.9613652 0.0 5.064502E-4 0.089 3042 tags=44%, list=20%, signal=54% HYDROGEN ION TRANSMEMBRANE TRANSPORT%GOBP%GO:1902600 HYDROGEN ION TRANSMEMBRANE TRANSPORT%GOBP%GO:1902600 27 -0.70250946 -1.9603578 0.0027472528 5.215251E-4 0.091 2619 tags=63%, list=17%, signal=76% DNA CONFORMATION CHANGE%GOBP%GO:0071103 DNA CONFORMATION CHANGE%GOBP%GO:0071103 153 -0.5224958 -1.9595517 0.0 5.25547E-4 0.092 3348 tags=41%, list=22%, signal=51% NUCLEOTIDE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%5696398 NUCLEOTIDE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%5696398 109 -0.536666 -1.9582891 0.0 5.292365E-4 0.092 4550 tags=52%, list=30%, signal=74% NEGATIVE REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032480 NEGATIVE REGULATION OF TYPE I INTERFERON PRODUCTION%GOBP%GO:0032480 41 -0.6459465 -1.9564114 0.0 5.3841807E-4 0.094 2878 tags=41%, list=19%, signal=51% TRNA PROCESSING IN THE NUCLEUS%REACTOME DATABASE ID RELEASE 60%6784531 TRNA PROCESSING IN THE NUCLEUS%REACTOME DATABASE ID RELEASE 60%6784531 51 -0.61869043 -1.9558545 0.0 5.3638633E-4 0.094 4293 tags=65%, list=28%, signal=90% POSITIVE REGULATION OF INTERFERON-BETA PRODUCTION%GOBP%GO:0032728 POSITIVE REGULATION OF INTERFERON-BETA PRODUCTION%GOBP%GO:0032728 25 -0.722417 -1.954207 0.0 5.5705325E-4 0.098 2051 tags=40%, list=13%, signal=46% PID_ATR_PATHWAY%MSIGDB_C2%PID_ATR_PATHWAY PID_ATR_PATHWAY%MSIGDB_C2%PID_ATR_PATHWAY 38 -0.64629865 -1.9536004 0.0 5.7188375E-4 0.101 2108 tags=42%, list=14%, signal=49% FC-EPSILON RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038095 FC-EPSILON RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038095 119 -0.5297879 -1.9525257 0.0 5.8640813E-4 0.104 2310 tags=37%, list=15%, signal=43% RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009201 RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009201 31 -0.6881294 -1.9525175 0.0 5.842282E-4 0.104 2619 tags=61%, list=17%, signal=74% ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0019886 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0019886 86 -0.5687603 -1.9521652 0.0 5.8748625E-4 0.105 1186 tags=30%, list=8%, signal=33% MAPK6 MAPK4 SIGNALING%REACTOME%R-HSA-5687128.3 MAPK6 MAPK4 SIGNALING%REACTOME%R-HSA-5687128.3 80 -0.57216614 -1.9506016 0.0 6.0673285E-4 0.107 2247 tags=40%, list=15%, signal=47% REGULATION OF MRNA STABILITY%GOBP%GO:0043488 REGULATION OF MRNA STABILITY%GOBP%GO:0043488 128 -0.5293813 -1.9495617 0.0 6.208823E-4 0.11 3337 tags=40%, list=22%, signal=51% NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0006289 NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0006289 105 -0.5338105 -1.9494491 0.0 6.18608E-4 0.11 3202 tags=38%, list=21%, signal=48% CHROMATIN ASSEMBLY OR DISASSEMBLY%GOBP%GO:0006333 CHROMATIN ASSEMBLY OR DISASSEMBLY%GOBP%GO:0006333 101 -0.5461536 -1.9472842 0.0 6.32833E-4 0.113 3319 tags=43%, list=22%, signal=54% PURINE RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009206 PURINE RIBONUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009206 31 -0.6881294 -1.9439821 0.0 6.894865E-4 0.121 2619 tags=61%, list=17%, signal=74% PROTEIN-DNA COMPLEX ASSEMBLY%GOBP%GO:0065004 PROTEIN-DNA COMPLEX ASSEMBLY%GOBP%GO:0065004 125 -0.5425714 -1.9438218 0.0 6.8698835E-4 0.121 3319 tags=48%, list=22%, signal=61% ATP BIOSYNTHETIC PROCESS%GOBP%GO:0006754 ATP BIOSYNTHETIC PROCESS%GOBP%GO:0006754 29 -0.6924556 -1.942719 0.0 6.95129E-4 0.123 2619 tags=66%, list=17%, signal=79% GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN TC-NER%REACTOME%R-HSA-6782210.1 GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN TC-NER%REACTOME%R-HSA-6782210.1 63 -0.58814156 -1.9420121 0.0 6.978945E-4 0.124 3042 tags=44%, list=20%, signal=55% ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE OR POLYSACCHARIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0002504 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE OR POLYSACCHARIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0002504 87 -0.56381136 -1.9403492 0.0 7.057367E-4 0.126 1186 tags=30%, list=8%, signal=32% EXTENSION OF TELOMERES%REACTOME DATABASE ID RELEASE 60%180786 EXTENSION OF TELOMERES%REACTOME DATABASE ID RELEASE 60%180786 30 -0.706926 -1.9401752 0.0 7.0321624E-4 0.126 3539 tags=77%, list=23%, signal=100% DNA DAMAGE BYPASS%REACTOME DATABASE ID RELEASE 60%73893 DNA DAMAGE BYPASS%REACTOME DATABASE ID RELEASE 60%73893 46 -0.63797146 -1.9383801 0.0 7.0071366E-4 0.126 3042 tags=48%, list=20%, signal=60% RIBONUCLEOPROTEIN COMPLEX ASSEMBLY%GOBP%GO:0022618 RIBONUCLEOPROTEIN COMPLEX ASSEMBLY%GOBP%GO:0022618 144 -0.52036244 -1.9347135 0.0 7.4551423E-4 0.134 4053 tags=41%, list=27%, signal=55% PID_IFNG_PATHWAY%MSIGDB_C2%PID_IFNG_PATHWAY PID_IFNG_PATHWAY%MSIGDB_C2%PID_IFNG_PATHWAY 38 -0.6427979 -1.9343433 0.0 7.533185E-4 0.135 344 tags=18%, list=2%, signal=19% CENP-A CONTAINING NUCLEOSOME ASSEMBLY%GOBP%GO:0034080 CENP-A CONTAINING NUCLEOSOME ASSEMBLY%GOBP%GO:0034080 30 -0.69550467 -1.9332829 0.0 7.663367E-4 0.138 3664 tags=70%, list=24%, signal=92% APOPTOSIS%REACTOME DATABASE ID RELEASE 60%109581 APOPTOSIS%REACTOME DATABASE ID RELEASE 60%109581 155 -0.51359844 -1.9304109 0.0 7.789642E-4 0.14 3345 tags=41%, list=22%, signal=52% NEGATIVE REGULATION OF MULTI-ORGANISM PROCESS%GOBP%GO:0043901 NEGATIVE REGULATION OF MULTI-ORGANISM PROCESS%GOBP%GO:0043901 115 -0.5226397 -1.9302055 0.0 7.7624054E-4 0.14 2069 tags=30%, list=14%, signal=34% IFN-GAMMA PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IFN-GAMMA PATHWAY IFN-GAMMA PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IFN-GAMMA PATHWAY 41 -0.62891424 -1.9290683 0.0 7.8877877E-4 0.143 344 tags=17%, list=2%, signal=17% DNA REPLICATION-INDEPENDENT NUCLEOSOME ORGANIZATION%GOBP%GO:0034724 DNA REPLICATION-INDEPENDENT NUCLEOSOME ORGANIZATION%GOBP%GO:0034724 42 -0.63563 -1.927628 0.0 8.265017E-4 0.151 3664 tags=60%, list=24%, signal=78% NON-CODING RNA METABOLISM%REACTOME%R-HSA-194441.1 NON-CODING RNA METABOLISM%REACTOME%R-HSA-194441.1 47 -0.61592245 -1.9259844 0.0 8.441733E-4 0.155 4293 tags=62%, list=28%, signal=86% SNRNA METABOLIC PROCESS%GOBP%GO:0016073 SNRNA METABOLIC PROCESS%GOBP%GO:0016073 75 -0.56968474 -1.9256154 0.0 8.5136667E-4 0.157 3669 tags=43%, list=24%, signal=56% PROGRAMMED CELL DEATH%REACTOME%R-HSA-5357801.1 PROGRAMMED CELL DEATH%REACTOME%R-HSA-5357801.1 158 -0.520468 -1.9253774 0.0 8.537287E-4 0.158 3345 tags=42%, list=22%, signal=53% HIV LIFE CYCLE%REACTOME DATABASE ID RELEASE 60%162587 HIV LIFE CYCLE%REACTOME DATABASE ID RELEASE 60%162587 133 -0.5260906 -1.925227 0.0 8.5080497E-4 0.158 4440 tags=48%, list=29%, signal=67% ATP SYNTHESIS COUPLED PROTON TRANSPORT%GOBP%GO:0015986 ATP SYNTHESIS COUPLED PROTON TRANSPORT%GOBP%GO:0015986 22 -0.7277409 -1.9251074 0.0 8.4790116E-4 0.158 2619 tags=73%, list=17%, signal=88% ANTIVIRAL MECHANISM BY IFN-STIMULATED GENES%REACTOME DATABASE ID RELEASE 60%1169410 ANTIVIRAL MECHANISM BY IFN-STIMULATED GENES%REACTOME DATABASE ID RELEASE 60%1169410 66 -0.59492356 -1.9247824 0.0 8.500785E-4 0.158 1140 tags=27%, list=7%, signal=29% CYTOSOLIC SENSORS OF PATHOGEN-ASSOCIATED DNA%REACTOME DATABASE ID RELEASE 60%1834949 CYTOSOLIC SENSORS OF PATHOGEN-ASSOCIATED DNA%REACTOME DATABASE ID RELEASE 60%1834949 66 -0.5760574 -1.92373 0.0 8.6738553E-4 0.162 2857 tags=38%, list=19%, signal=46% RIBONUCLEOPROTEIN COMPLEX SUBUNIT ORGANIZATION%GOBP%GO:0071826 RIBONUCLEOPROTEIN COMPLEX SUBUNIT ORGANIZATION%GOBP%GO:0071826 156 -0.5066931 -1.9224079 0.0 9.091344E-4 0.168 4053 tags=40%, list=27%, signal=54% REGULATION OF RNA STABILITY%GOBP%GO:0043487 REGULATION OF RNA STABILITY%GOBP%GO:0043487 134 -0.52189153 -1.9218845 0.0 9.210423E-4 0.17 1606 tags=25%, list=11%, signal=27% MITOCHONDRIAL TRANSPORT%GOBP%GO:0006839 MITOCHONDRIAL TRANSPORT%GOBP%GO:0006839 173 -0.504969 -1.9154234 0.0 0.0010216306 0.188 4225 tags=46%, list=28%, signal=63% POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL%GOBP%GO:1903322 POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL%GOBP%GO:1903322 166 -0.5109319 -1.9134703 0.0 0.0010533357 0.194 2310 tags=34%, list=15%, signal=39% DNA REPLICATION-INDEPENDENT NUCLEOSOME ASSEMBLY%GOBP%GO:0006336 DNA REPLICATION-INDEPENDENT NUCLEOSOME ASSEMBLY%GOBP%GO:0006336 41 -0.63879627 -1.9131185 0.0 0.0010595949 0.196 3664 tags=61%, list=24%, signal=80% MITOCHONDRIAL ATP SYNTHESIS COUPLED PROTON TRANSPORT%GOBP%GO:0042776 MITOCHONDRIAL ATP SYNTHESIS COUPLED PROTON TRANSPORT%GOBP%GO:0042776 19 -0.7609424 -1.9129053 0.0 0.0010560746 0.196 2619 tags=79%, list=17%, signal=95% TRAF6 MEDIATED IRF7 ACTIVATION%REACTOME%R-HSA-933541.1 TRAF6 MEDIATED IRF7 ACTIVATION%REACTOME%R-HSA-933541.1 19 -0.7579661 -1.9120857 0.0026737968 0.001067155 0.199 430 tags=32%, list=3%, signal=32% TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE%REACTOME DATABASE ID RELEASE 60%110313 TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE%REACTOME DATABASE ID RELEASE 60%110313 38 -0.6497229 -1.9109284 0.0 0.0010833179 0.201 3290 tags=53%, list=22%, signal=67% TRANSCRIPTION-COUPLED NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0006283 TRANSCRIPTION-COUPLED NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0006283 72 -0.5683702 -1.9108895 0.0 0.0010797544 0.201 3042 tags=40%, list=20%, signal=50% ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0002495 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS II%GOBP%GO:0002495 87 -0.56381136 -1.9108716 0.0 0.0010762142 0.201 1186 tags=30%, list=8%, signal=32% TERMINATION OF TRANSLESION DNA SYNTHESIS%REACTOME DATABASE ID RELEASE 60%5656169 TERMINATION OF TRANSLESION DNA SYNTHESIS%REACTOME DATABASE ID RELEASE 60%5656169 32 -0.6722085 -1.910689 0.0 0.0010726972 0.201 3290 tags=56%, list=22%, signal=72% POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS%GOBP%GO:2000108 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS%GOBP%GO:2000108 18 -0.77162445 -1.9092804 0.0 0.0010880484 0.204 1315 tags=50%, list=9%, signal=55% TRANSCRIPTIONAL REGULATION BY SMALL RNAS%REACTOME%R-HSA-5578749.3 TRANSCRIPTIONAL REGULATION BY SMALL RNAS%REACTOME%R-HSA-5578749.3 70 -0.57645607 -1.9086148 0.0 0.0010987214 0.207 4337 tags=57%, list=29%, signal=80% TELOMERE C-STRAND (LAGGING STRAND) SYNTHESIS%REACTOME DATABASE ID RELEASE 60%174417 TELOMERE C-STRAND (LAGGING STRAND) SYNTHESIS%REACTOME DATABASE ID RELEASE 60%174417 24 -0.71641487 -1.9081692 0.0 0.0011048759 0.209 3042 tags=71%, list=20%, signal=88% REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001910 REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001910 29 -0.6912623 -1.907696 0.0 0.0011060691 0.21 2140 tags=45%, list=14%, signal=52% PURINE NUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009145 PURINE NUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009145 31 -0.6881294 -1.9065045 0.0 0.0011120645 0.212 2619 tags=61%, list=17%, signal=74% NUCLEAR DIVISION%GOBP%GO:0000280 NUCLEAR DIVISION%GOBP%GO:0000280 174 -0.48983797 -1.9065034 0.0 0.0011085002 0.212 3642 tags=44%, list=24%, signal=58% REGULATION OF RAS BY GAPS%REACTOME DATABASE ID RELEASE 60%5658442 REGULATION OF RAS BY GAPS%REACTOME DATABASE ID RELEASE 60%5658442 65 -0.574416 -1.9039851 0.0 0.0011757493 0.221 1616 tags=38%, list=11%, signal=43% INNATE IMMUNE RESPONSE-ACTIVATING SIGNAL TRANSDUCTION%GOBP%GO:0002758 INNATE IMMUNE RESPONSE-ACTIVATING SIGNAL TRANSDUCTION%GOBP%GO:0002758 183 -0.5083472 -1.9012214 0.0 0.0012280243 0.232 2909 tags=39%, list=19%, signal=47% LATE PHASE OF HIV LIFE CYCLE%REACTOME DATABASE ID RELEASE 60%162599 LATE PHASE OF HIV LIFE CYCLE%REACTOME DATABASE ID RELEASE 60%162599 120 -0.5204762 -1.8974507 0.0 0.001313294 0.248 4440 tags=48%, list=29%, signal=67% ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS%REACTOME DATABASE ID RELEASE 60%176187 ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS%REACTOME DATABASE ID RELEASE 60%176187 31 -0.6644178 -1.8963839 0.0 0.0013186389 0.25 3373 tags=68%, list=22%, signal=87% SNRNP ASSEMBLY%REACTOME DATABASE ID RELEASE 60%191859 SNRNP ASSEMBLY%REACTOME DATABASE ID RELEASE 60%191859 47 -0.61592245 -1.8934721 0.0 0.0013802134 0.261 4293 tags=62%, list=28%, signal=86% RNA TRANSPORT%GOBP%GO:0050658 RNA TRANSPORT%GOBP%GO:0050658 121 -0.5091772 -1.8932953 0.0 0.0013850702 0.263 4293 tags=47%, list=28%, signal=65% SPLICEOSOMAL SNRNP ASSEMBLY%GOBP%GO:0000387 SPLICEOSOMAL SNRNP ASSEMBLY%GOBP%GO:0000387 34 -0.6579794 -1.8932847 0.0 0.0013807282 0.263 2043 tags=44%, list=13%, signal=51% CYTOCHROME COMPLEX ASSEMBLY%GOBP%GO:0017004 CYTOCHROME COMPLEX ASSEMBLY%GOBP%GO:0017004 16 -0.78772086 -1.8921587 0.0 0.001404129 0.267 2210 tags=63%, list=15%, signal=73% PROCESSING OF DNA DOUBLE-STRAND BREAK ENDS%REACTOME%R-HSA-5693607.1 PROCESSING OF DNA DOUBLE-STRAND BREAK ENDS%REACTOME%R-HSA-5693607.1 78 -0.55495024 -1.8918937 0.0 0.0014088623 0.269 4440 tags=59%, list=29%, signal=83% REGULATION OF DNA-TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS%GOBP%GO:0043620 REGULATION OF DNA-TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS%GOBP%GO:0043620 109 -0.51719254 -1.8917066 0.0 0.001404487 0.269 2247 tags=33%, list=15%, signal=38% COSTIMULATION BY THE CD28 FAMILY%REACTOME%R-HSA-388841.2 COSTIMULATION BY THE CD28 FAMILY%REACTOME%R-HSA-388841.2 62 -0.5825266 -1.8903689 0.0 0.0014279007 0.272 3240 tags=50%, list=21%, signal=63% ENERGY COUPLED PROTON TRANSPORT, DOWN ELECTROCHEMICAL GRADIENT%GOBP%GO:0015985 ENERGY COUPLED PROTON TRANSPORT, DOWN ELECTROCHEMICAL GRADIENT%GOBP%GO:0015985 22 -0.7277409 -1.8882909 0.0028985508 0.0014824158 0.281 2619 tags=73%, list=17%, signal=88% BIOCARTA_ATRBRCA_PATHWAY%MSIGDB_C2%BIOCARTA_ATRBRCA_PATHWAY BIOCARTA_ATRBRCA_PATHWAY%MSIGDB_C2%BIOCARTA_ATRBRCA_PATHWAY 21 -0.7289328 -1.886859 0.0 0.0014960032 0.285 1415 tags=38%, list=9%, signal=42% HOMOLOGY DIRECTED REPAIR%REACTOME%R-HSA-5693538.1 HOMOLOGY DIRECTED REPAIR%REACTOME%R-HSA-5693538.1 112 -0.5190457 -1.886346 0.0 0.001518639 0.287 5078 tags=65%, list=33%, signal=97% INFLUENZA INFECTION%REACTOME%R-HSA-168254.1 INFLUENZA INFECTION%REACTOME%R-HSA-168254.1 143 -0.50571865 -1.8862524 0.0 0.0015184226 0.288 4639 tags=48%, list=30%, signal=69% NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250941 NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250941 80 -0.553035 -1.885994 0.0 0.0015184025 0.289 3782 tags=44%, list=25%, signal=58% MITOCHONDRIAL MEMBRANE ORGANIZATION%GOBP%GO:0007006 MITOCHONDRIAL MEMBRANE ORGANIZATION%GOBP%GO:0007006 98 -0.5374358 -1.8845861 0.0 0.0015630673 0.298 4118 tags=49%, list=27%, signal=67% REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002703 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002703 85 -0.54601693 -1.8829484 0.0 0.0015806416 0.301 2167 tags=34%, list=14%, signal=40% POST-ELONGATION PROCESSING OF THE TRANSCRIPT%REACTOME DATABASE ID RELEASE 60%76044 POST-ELONGATION PROCESSING OF THE TRANSCRIPT%REACTOME DATABASE ID RELEASE 60%76044 52 -0.5921277 -1.8822646 0.0 0.0015982965 0.304 3885 tags=50%, list=26%, signal=67% HDR THROUGH HOMOLOGOUS RECOMBINATION (HRR)%REACTOME%R-HSA-5685942.1 HDR THROUGH HOMOLOGOUS RECOMBINATION (HRR)%REACTOME%R-HSA-5685942.1 59 -0.5778257 -1.8775829 0.0 0.0017843632 0.338 5150 tags=73%, list=34%, signal=110% POSITIVE REGULATION OF CELL KILLING%GOBP%GO:0031343 POSITIVE REGULATION OF CELL KILLING%GOBP%GO:0031343 21 -0.71935445 -1.8760569 0.0 0.0018233086 0.344 2140 tags=48%, list=14%, signal=55% ACTIVATION OF E2F1 TARGET GENES AT G1 S%REACTOME%R-HSA-539107.4 ACTIVATION OF E2F1 TARGET GENES AT G1 S%REACTOME%R-HSA-539107.4 26 -0.6880754 -1.8746762 0.0 0.0018671164 0.351 4118 tags=77%, list=27%, signal=105% DNA SYNTHESIS INVOLVED IN DNA REPAIR%GOBP%GO:0000731 DNA SYNTHESIS INVOLVED IN DNA REPAIR%GOBP%GO:0000731 66 -0.56700677 -1.8708417 0.0 0.0019713906 0.365 3584 tags=45%, list=24%, signal=59% CRISTAE FORMATION%REACTOME%R-HSA-8949613.1 CRISTAE FORMATION%REACTOME%R-HSA-8949613.1 28 -0.6741052 -1.8701253 0.0031347962 0.0019880757 0.369 3765 tags=75%, list=25%, signal=99% POSITIVE REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903052 POSITIVE REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903052 151 -0.4949816 -1.8700727 0.0 0.0019866694 0.37 3357 tags=44%, list=22%, signal=56% NUCLEIC ACID TRANSPORT%GOBP%GO:0050657 NUCLEIC ACID TRANSPORT%GOBP%GO:0050657 121 -0.5091772 -1.8690921 0.0 0.0020154996 0.376 4293 tags=47%, list=28%, signal=65% CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION%REACTOME DATABASE ID RELEASE 60%109688 CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION%REACTOME DATABASE ID RELEASE 60%109688 52 -0.5921277 -1.8681725 0.0 0.0020622553 0.385 3885 tags=50%, list=26%, signal=67% NUCLEOBASE-CONTAINING COMPOUND TRANSPORT%GOBP%GO:0015931 NUCLEOBASE-CONTAINING COMPOUND TRANSPORT%GOBP%GO:0015931 136 -0.49970058 -1.8676649 0.0 0.0020650192 0.385 4293 tags=46%, list=28%, signal=64% REGULATION OF INTERFERON-GAMMA-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060334 REGULATION OF INTERFERON-GAMMA-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060334 17 -0.76717365 -1.8674275 0.0 0.0020631365 0.386 512 tags=35%, list=3%, signal=36% RESPONSE TO INTERFERON-BETA%GOBP%GO:0035456 RESPONSE TO INTERFERON-BETA%GOBP%GO:0035456 17 -0.75803334 -1.8673592 0.0 0.002061372 0.387 2915 tags=71%, list=19%, signal=87% REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS%GOBP%GO:0043618 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS%GOBP%GO:0043618 104 -0.5212184 -1.8659213 0.0 0.0020981296 0.396 2247 tags=34%, list=15%, signal=39% HDR THROUGH HOMOLOGOUS RECOMBINATION (HR) OR SINGLE STRAND ANNEALING (SSA)%REACTOME%R-HSA-5693567.1 HDR THROUGH HOMOLOGOUS RECOMBINATION (HR) OR SINGLE STRAND ANNEALING (SSA)%REACTOME%R-HSA-5693567.1 106 -0.5168148 -1.8643733 0.0 0.0021396682 0.405 5078 tags=65%, list=33%, signal=97% LYMPHOCYTE COSTIMULATION%GOBP%GO:0031294 LYMPHOCYTE COSTIMULATION%GOBP%GO:0031294 58 -0.5776844 -1.8632832 0.0 0.0022018114 0.414 1474 tags=41%, list=10%, signal=46% PYRIMIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0072527 PYRIMIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0072527 48 -0.5917918 -1.8629113 0.0 0.0021997197 0.415 1691 tags=44%, list=11%, signal=49% RESOLUTION OF AP SITES VIA THE MULTIPLE-NUCLEOTIDE PATCH REPLACEMENT PATHWAY%REACTOME%R-HSA-110373.1 RESOLUTION OF AP SITES VIA THE MULTIPLE-NUCLEOTIDE PATCH REPLACEMENT PATHWAY%REACTOME%R-HSA-110373.1 25 -0.69843125 -1.8626096 0.0 0.0022019525 0.417 3152 tags=64%, list=21%, signal=81% T CELL COSTIMULATION%GOBP%GO:0031295 T CELL COSTIMULATION%GOBP%GO:0031295 57 -0.57997394 -1.8610176 0.0 0.0022422913 0.421 1474 tags=42%, list=10%, signal=46% ATR SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ATR SIGNALING PATHWAY ATR SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ATR SIGNALING PATHWAY 39 -0.62326616 -1.8569714 0.0 0.0023551243 0.438 2108 tags=41%, list=14%, signal=48% CRISTAE FORMATION%GOBP%GO:0042407 CRISTAE FORMATION%GOBP%GO:0042407 24 -0.70310026 -1.8566445 0.002967359 0.0023527984 0.439 2619 tags=71%, list=17%, signal=85% G2 M DNA DAMAGE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69473 G2 M DNA DAMAGE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69473 75 -0.55070174 -1.854547 0.0 0.0024298995 0.448 4339 tags=55%, list=29%, signal=76% REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002697 REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002697 190 -0.47148117 -1.8538458 0.0 0.0024525537 0.452 2167 tags=31%, list=14%, signal=36% SRP-DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%REACTOME%R-HSA-1799339.1 SRP-DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%REACTOME%R-HSA-1799339.1 108 -0.5171406 -1.85253 0.0 0.0025090962 0.459 6240 tags=67%, list=41%, signal=112% BIOCARTA_CTLA4_PATHWAY%MSIGDB_C2%BIOCARTA_CTLA4_PATHWAY BIOCARTA_CTLA4_PATHWAY%MSIGDB_C2%BIOCARTA_CTLA4_PATHWAY 18 -0.74677545 -1.8523417 0.0025641026 0.0025146948 0.46 1474 tags=61%, list=10%, signal=68% RNA POLYMERASE II TRANSCRIPTION INITIATION AND PROMOTER CLEARANCE%REACTOME DATABASE ID RELEASE 60%76042 RNA POLYMERASE II TRANSCRIPTION INITIATION AND PROMOTER CLEARANCE%REACTOME DATABASE ID RELEASE 60%76042 45 -0.5844826 -1.851325 0.0 0.0025655623 0.468 3127 tags=42%, list=21%, signal=53% TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRON-CONTAINING TRANSCRIPT%REACTOME%R-HSA-159236.3 TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRON-CONTAINING TRANSCRIPT%REACTOME%R-HSA-159236.3 54 -0.57995 -1.8509938 0.0 0.0025707933 0.468 4293 tags=54%, list=28%, signal=75% TRANSLESION SYNTHESIS%GOBP%GO:0019985 TRANSLESION SYNTHESIS%GOBP%GO:0019985 39 -0.6322245 -1.8507224 0.0 0.0025759803 0.47 3290 tags=49%, list=22%, signal=62% ABC-FAMILY PROTEINS MEDIATED TRANSPORT%REACTOME DATABASE ID RELEASE 60%382556 ABC-FAMILY PROTEINS MEDIATED TRANSPORT%REACTOME DATABASE ID RELEASE 60%382556 93 -0.5381433 -1.8504368 0.0 0.0025728145 0.471 3337 tags=46%, list=22%, signal=59% INFLUENZA LIFE CYCLE%REACTOME%R-HSA-168255.2 INFLUENZA LIFE CYCLE%REACTOME%R-HSA-168255.2 133 -0.50226235 -1.8496157 0.0 0.0026271665 0.479 5794 tags=62%, list=38%, signal=99% INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION%REACTOME%R-HSA-168273.2 INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION%REACTOME%R-HSA-168273.2 125 -0.50373864 -1.8491476 0.0 0.0026484942 0.482 5794 tags=62%, list=38%, signal=100% RNA POLYMERASE II TRANSCRIPTION TERMINATION%REACTOME%R-HSA-73856.2 RNA POLYMERASE II TRANSCRIPTION TERMINATION%REACTOME%R-HSA-73856.2 52 -0.5921277 -1.8481872 0.0 0.0026781776 0.488 3885 tags=50%, list=26%, signal=67% RHO GTPASES ACTIVATE FORMINS%REACTOME DATABASE ID RELEASE 60%5663220 RHO GTPASES ACTIVATE FORMINS%REACTOME DATABASE ID RELEASE 60%5663220 105 -0.52512914 -1.8455151 0.0 0.0027486708 0.497 3318 tags=45%, list=22%, signal=57% REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:2001267 REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:2001267 18 -0.7457441 -1.842313 0.0 0.0028709688 0.51 294 tags=28%, list=2%, signal=28% REGULATION OF T CELL ACTIVATION%GOBP%GO:0050863 REGULATION OF T CELL ACTIVATION%GOBP%GO:0050863 188 -0.48237103 -1.8416857 0.0 0.0029032943 0.518 2363 tags=41%, list=16%, signal=49% ORGANELLE FISSION%GOBP%GO:0048285 ORGANELLE FISSION%GOBP%GO:0048285 194 -0.4761716 -1.8413279 0.0 0.0029075507 0.519 3642 tags=43%, list=24%, signal=56% RIBONUCLEOPROTEIN COMPLEX LOCALIZATION%GOBP%GO:0071166 RIBONUCLEOPROTEIN COMPLEX LOCALIZATION%GOBP%GO:0071166 104 -0.50616246 -1.8401096 0.0 0.0029477666 0.526 4293 tags=47%, list=28%, signal=65% SNRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0042795 SNRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0042795 64 -0.5439766 -1.8385911 0.0 0.0029960154 0.527 3582 tags=39%, list=24%, signal=51% FANCONI ANEMIA PATHWAY%REACTOME DATABASE ID RELEASE 60%6783310 FANCONI ANEMIA PATHWAY%REACTOME DATABASE ID RELEASE 60%6783310 31 -0.64310384 -1.8378066 0.0 0.0030079947 0.529 4440 tags=71%, list=29%, signal=100% PCNA-DEPENDENT LONG PATCH BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%5651801 PCNA-DEPENDENT LONG PATCH BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 60%5651801 21 -0.7214809 -1.837395 0.0 0.0030160812 0.532 3042 tags=67%, list=20%, signal=83% G1 S-SPECIFIC TRANSCRIPTION%REACTOME%R-HSA-69205.2 G1 S-SPECIFIC TRANSCRIPTION%REACTOME%R-HSA-69205.2 26 -0.6880754 -1.8370628 0.0 0.0030157992 0.532 4118 tags=77%, list=27%, signal=105% GENERATION OF SECOND MESSENGER MOLECULES%REACTOME DATABASE ID RELEASE 60%202433 GENERATION OF SECOND MESSENGER MOLECULES%REACTOME DATABASE ID RELEASE 60%202433 29 -0.65956765 -1.8337072 0.0 0.0031627584 0.551 2616 tags=76%, list=17%, signal=91% RNA 3'-END PROCESSING%GOBP%GO:0031123 RNA 3'-END PROCESSING%GOBP%GO:0031123 82 -0.5394187 -1.8328015 0.0 0.0032055292 0.559 4067 tags=46%, list=27%, signal=63% DNA DOUBLE-STRAND BREAK REPAIR%REACTOME%R-HSA-5693532.2 DNA DOUBLE-STRAND BREAK REPAIR%REACTOME%R-HSA-5693532.2 140 -0.4859764 -1.8301301 0.0 0.0033313802 0.569 3501 tags=42%, list=23%, signal=54% ANATOMICAL STRUCTURE HOMEOSTASIS%GOBP%GO:0060249 ANATOMICAL STRUCTURE HOMEOSTASIS%GOBP%GO:0060249 152 -0.47505182 -1.8291299 0.0 0.0033737933 0.575 3380 tags=36%, list=22%, signal=46% TRANSLATION%REACTOME DATABASE ID RELEASE 60%72766 TRANSLATION%REACTOME DATABASE ID RELEASE 60%72766 194 -0.47482798 -1.828199 0.0 0.0034516922 0.585 5697 tags=56%, list=37%, signal=88% TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM%REACTOME%R-HSA-72202.2 TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM%REACTOME%R-HSA-72202.2 63 -0.5535907 -1.827143 0.0 0.003481771 0.589 4293 tags=51%, list=28%, signal=70% GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR (GG-NER)%REACTOME DATABASE ID RELEASE 60%5696399 GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR (GG-NER)%REACTOME DATABASE ID RELEASE 60%5696399 84 -0.5306105 -1.8260254 0.0 0.0035394807 0.599 4550 tags=54%, list=30%, signal=76% ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS%GOBP%GO:0015980 ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS%GOBP%GO:0015980 154 -0.48523834 -1.8253762 0.0 0.003596934 0.607 3066 tags=48%, list=20%, signal=60% POSITIVE REGULATION OF INTERFERON-ALPHA PRODUCTION%GOBP%GO:0032727 POSITIVE REGULATION OF INTERFERON-ALPHA PRODUCTION%GOBP%GO:0032727 15 -0.7604238 -1.8247939 0.0 0.0036065658 0.61 2055 tags=47%, list=14%, signal=54% NUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009124 NUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009124 46 -0.58827674 -1.8247895 0.0 0.0035970747 0.61 2619 tags=50%, list=17%, signal=60% FORMATION OF ATP BY CHEMIOSMOTIC COUPLING%REACTOME%R-HSA-163210.2 FORMATION OF ATP BY CHEMIOSMOTIC COUPLING%REACTOME%R-HSA-163210.2 16 -0.76324123 -1.8213577 0.0 0.003835568 0.628 2619 tags=81%, list=17%, signal=98% RNA LOCALIZATION%GOBP%GO:0006403 RNA LOCALIZATION%GOBP%GO:0006403 141 -0.48984843 -1.8210661 0.0 0.003829379 0.628 4512 tags=48%, list=30%, signal=67% NUCLEIC ACID PHOSPHODIESTER BOND HYDROLYSIS%GOBP%GO:0090305 NUCLEIC ACID PHOSPHODIESTER BOND HYDROLYSIS%GOBP%GO:0090305 111 -0.5017634 -1.8195633 0.0 0.0039086095 0.638 4721 tags=55%, list=31%, signal=79% CAP-DEPENDENT TRANSLATION INITIATION%REACTOME%R-HSA-72737.2 CAP-DEPENDENT TRANSLATION INITIATION%REACTOME%R-HSA-72737.2 115 -0.4959831 -1.819251 0.0 0.0039179106 0.64 5794 tags=60%, list=38%, signal=96% NORC NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME%R-HSA-427413.1 NORC NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME%R-HSA-427413.1 77 -0.54412365 -1.8174537 0.0 0.0040261447 0.648 3782 tags=43%, list=25%, signal=57% ESTABLISHMENT OF RNA LOCALIZATION%GOBP%GO:0051236 ESTABLISHMENT OF RNA LOCALIZATION%GOBP%GO:0051236 123 -0.4997401 -1.8167905 0.0 0.00404624 0.651 4334 tags=47%, list=28%, signal=65% RIBOSOMAL SMALL SUBUNIT BIOGENESIS%GOBP%GO:0042274 RIBOSOMAL SMALL SUBUNIT BIOGENESIS%GOBP%GO:0042274 57 -0.5664196 -1.8162755 0.0 0.0040742024 0.655 4193 tags=56%, list=28%, signal=77% MITOTIC METAPHASE PLATE CONGRESSION%GOBP%GO:0007080 MITOTIC METAPHASE PLATE CONGRESSION%GOBP%GO:0007080 40 -0.59126985 -1.8132442 0.0 0.0042494973 0.673 1915 tags=38%, list=13%, signal=43% RNA POLYMERASE II TRANSCRIBES SNRNA GENES%REACTOME DATABASE ID RELEASE 60%6807505 RNA POLYMERASE II TRANSCRIBES SNRNA GENES%REACTOME DATABASE ID RELEASE 60%6807505 68 -0.5431177 -1.81106 0.0 0.004371894 0.685 3582 tags=40%, list=24%, signal=52% CHROMATIN REMODELING%GOBP%GO:0006338 CHROMATIN REMODELING%GOBP%GO:0006338 114 -0.50044394 -1.8104028 0.0 0.004416974 0.687 2711 tags=36%, list=18%, signal=43% CHEMOKINE RECEPTORS BIND CHEMOKINES%REACTOME%R-HSA-380108.3 CHEMOKINE RECEPTORS BIND CHEMOKINES%REACTOME%R-HSA-380108.3 33 -0.63352466 -1.8102632 0.0 0.004413332 0.689 1660 tags=42%, list=11%, signal=48% HUMORAL IMMUNE RESPONSE%GOBP%GO:0006959 HUMORAL IMMUNE RESPONSE%GOBP%GO:0006959 87 -0.52005565 -1.8101834 0.0 0.004402073 0.689 1985 tags=32%, list=13%, signal=37% RNA POLYMERASE II TRANSCRIPTION PRE-INITIATION AND PROMOTER OPENING%REACTOME DATABASE ID RELEASE 60%73779 RNA POLYMERASE II TRANSCRIPTION PRE-INITIATION AND PROMOTER OPENING%REACTOME DATABASE ID RELEASE 60%73779 45 -0.5844826 -1.807764 0.0033898305 0.004544216 0.702 3127 tags=42%, list=21%, signal=53% ATP-DEPENDENT CHROMATIN REMODELING%GOBP%GO:0043044 ATP-DEPENDENT CHROMATIN REMODELING%GOBP%GO:0043044 57 -0.5596563 -1.8077314 0.003984064 0.004540155 0.703 3746 tags=54%, list=25%, signal=72% IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON-LYMPHOID CELL%REACTOME DATABASE ID RELEASE 60%198933 IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON-LYMPHOID CELL%REACTOME DATABASE ID RELEASE 60%198933 89 -0.519586 -1.8016839 0.0 0.004966617 0.737 3115 tags=51%, list=20%, signal=63% NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN CONTAINING SIGNALING PATHWAY%GOBP%GO:0070423 NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN CONTAINING SIGNALING PATHWAY%GOBP%GO:0070423 25 -0.67453504 -1.8012877 0.0 0.004972564 0.739 2310 tags=40%, list=15%, signal=47% REGULATION OF DEFENSE RESPONSE TO VIRUS BY HOST%GOBP%GO:0050691 REGULATION OF DEFENSE RESPONSE TO VIRUS BY HOST%GOBP%GO:0050691 20 -0.7230491 -1.8011727 0.0 0.00496758 0.739 216 tags=30%, list=1%, signal=30% HIV TRANSCRIPTION INITIATION%REACTOME%R-HSA-167161.2 HIV TRANSCRIPTION INITIATION%REACTOME%R-HSA-167161.2 45 -0.5844826 -1.8004181 0.0 0.005007341 0.74 3127 tags=42%, list=21%, signal=53% RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071426 RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071426 102 -0.5045087 -1.8002484 0.0 0.0050022197 0.74 4293 tags=47%, list=28%, signal=65% SUMOYLATION OF DNA REPLICATION PROTEINS%REACTOME DATABASE ID RELEASE 60%4615885 SUMOYLATION OF DNA REPLICATION PROTEINS%REACTOME DATABASE ID RELEASE 60%4615885 40 -0.59033537 -1.7995405 0.0 0.0050448873 0.741 4293 tags=58%, list=28%, signal=80% AEROBIC RESPIRATION%GOBP%GO:0009060 AEROBIC RESPIRATION%GOBP%GO:0009060 42 -0.5878158 -1.7986206 0.0 0.005113376 0.748 5539 tags=81%, list=36%, signal=127% BASE-EXCISION REPAIR%GOBP%GO:0006284 BASE-EXCISION REPAIR%GOBP%GO:0006284 36 -0.60517514 -1.7980926 0.0 0.005122555 0.751 2772 tags=42%, list=18%, signal=51% B CELL MEDIATED IMMUNITY%GOBP%GO:0019724 B CELL MEDIATED IMMUNITY%GOBP%GO:0019724 23 -0.6898388 -1.7961851 0.002754821 0.0052860267 0.761 2195 tags=52%, list=14%, signal=61% REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903050 REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903050 194 -0.4577019 -1.794275 0.0 0.005419861 0.768 2265 tags=29%, list=15%, signal=34% CONDENSATION OF PROPHASE CHROMOSOMES%REACTOME%R-HSA-2299718.1 CONDENSATION OF PROPHASE CHROMOSOMES%REACTOME%R-HSA-2299718.1 43 -0.58274287 -1.7935957 0.0 0.0054758056 0.774 5479 tags=70%, list=36%, signal=109% PROTEIN SUMOYLATION%GOBP%GO:0016925 PROTEIN SUMOYLATION%GOBP%GO:0016925 64 -0.5516614 -1.7935722 0.0 0.005469606 0.774 4384 tags=45%, list=29%, signal=63% RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009156 RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009156 45 -0.5771134 -1.792706 0.0 0.005539909 0.78 2619 tags=49%, list=17%, signal=59% RNA POLYMERASE I CHAIN ELONGATION%REACTOME%R-HSA-73777.3 RNA POLYMERASE I CHAIN ELONGATION%REACTOME%R-HSA-73777.3 61 -0.5465995 -1.7919463 0.0 0.0055952384 0.787 3782 tags=46%, list=25%, signal=61% REGULATION OF LEUKOCYTE DEGRANULATION%GOBP%GO:0043300 REGULATION OF LEUKOCYTE DEGRANULATION%GOBP%GO:0043300 25 -0.6585823 -1.7904453 0.0 0.00570428 0.795 2167 tags=36%, list=14%, signal=42% RNA POLYMERASE II PROMOTER ESCAPE%REACTOME DATABASE ID RELEASE 60%73776 RNA POLYMERASE II PROMOTER ESCAPE%REACTOME DATABASE ID RELEASE 60%73776 45 -0.5844826 -1.7900698 0.0 0.005729876 0.796 3127 tags=42%, list=21%, signal=53% RNA POLYMERASE II TRANSCRIPTION INITIATION%REACTOME DATABASE ID RELEASE 60%75953 RNA POLYMERASE II TRANSCRIPTION INITIATION%REACTOME DATABASE ID RELEASE 60%75953 45 -0.5844826 -1.7896873 0.0 0.005737371 0.799 3127 tags=42%, list=21%, signal=53% POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002699 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002699 95 -0.5078436 -1.7891613 0.0 0.0057701073 0.802 2167 tags=35%, list=14%, signal=40% MATURATION OF SSU-RRNA FROM TRICISTRONIC RRNA TRANSCRIPT (SSU-RRNA, 5.8S RRNA, LSU-RRNA)%GOBP%GO:0000462 MATURATION OF SSU-RRNA FROM TRICISTRONIC RRNA TRANSCRIPT (SSU-RRNA, 5.8S RRNA, LSU-RRNA)%GOBP%GO:0000462 31 -0.63367224 -1.7880775 0.0028901733 0.005852403 0.807 4193 tags=61%, list=28%, signal=84% RESPONSE TO TUMOR NECROSIS FACTOR%GOBP%GO:0034612 RESPONSE TO TUMOR NECROSIS FACTOR%GOBP%GO:0034612 170 -0.46359566 -1.7860329 0.0 0.0060460037 0.818 2247 tags=35%, list=15%, signal=41% POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002705 POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002705 48 -0.5826105 -1.7833595 0.003875969 0.0063004256 0.834 2167 tags=31%, list=14%, signal=36% NONSENSE MEDIATED DECAY (NMD) INDEPENDENT OF THE EXON JUNCTION COMPLEX (EJC)%REACTOME%R-HSA-975956.1 NONSENSE MEDIATED DECAY (NMD) INDEPENDENT OF THE EXON JUNCTION COMPLEX (EJC)%REACTOME%R-HSA-975956.1 91 -0.50172883 -1.7830657 0.0 0.0062993676 0.836 6240 tags=65%, list=41%, signal=109% VIRAL TRANSCRIPTION%GOBP%GO:0019083 VIRAL TRANSCRIPTION%GOBP%GO:0019083 108 -0.50007844 -1.7817638 0.0 0.006384411 0.841 5794 tags=59%, list=38%, signal=95% RNA POLYMERASE II HIV PROMOTER ESCAPE%REACTOME%R-HSA-167162.2 RNA POLYMERASE II HIV PROMOTER ESCAPE%REACTOME%R-HSA-167162.2 45 -0.5844826 -1.7814568 0.0 0.0063978815 0.841 3127 tags=42%, list=21%, signal=53% MYD88-INDEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002756 MYD88-INDEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002756 32 -0.62032217 -1.7809846 0.0 0.0064216554 0.843 2753 tags=41%, list=18%, signal=49% ANTIMICROBIAL HUMORAL RESPONSE%GOBP%GO:0019730 ANTIMICROBIAL HUMORAL RESPONSE%GOBP%GO:0019730 38 -0.60150373 -1.7799084 0.0 0.006480321 0.847 2968 tags=47%, list=20%, signal=59% LAGGING STRAND SYNTHESIS%REACTOME DATABASE ID RELEASE 60%69186 LAGGING STRAND SYNTHESIS%REACTOME DATABASE ID RELEASE 60%69186 20 -0.7181858 -1.778552 0.0052083335 0.006591735 0.853 3042 tags=70%, list=20%, signal=87% RECOGNITION OF DNA DAMAGE BY PCNA-CONTAINING REPLICATION COMPLEX%REACTOME%R-HSA-110314.1 RECOGNITION OF DNA DAMAGE BY PCNA-CONTAINING REPLICATION COMPLEX%REACTOME%R-HSA-110314.1 29 -0.6498777 -1.7777628 0.0 0.0066392124 0.854 3042 tags=55%, list=20%, signal=69% NUCLEOTIDE-BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY%GOBP%GO:0035872 NUCLEOTIDE-BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY%GOBP%GO:0035872 26 -0.6496456 -1.7770694 0.0 0.0066860653 0.855 2803 tags=42%, list=18%, signal=52% CELLULAR RESPONSE TO VIRUS%GOBP%GO:0098586 CELLULAR RESPONSE TO VIRUS%GOBP%GO:0098586 16 -0.73893005 -1.7768668 0.0072639226 0.006673785 0.856 1365 tags=38%, list=9%, signal=41% RNA EXPORT FROM NUCLEUS%GOBP%GO:0006405 RNA EXPORT FROM NUCLEUS%GOBP%GO:0006405 108 -0.49899223 -1.7765139 0.0 0.0066998755 0.858 4293 tags=46%, list=28%, signal=64% L13A-MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION%REACTOME DATABASE ID RELEASE 60%156827 L13A-MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION%REACTOME DATABASE ID RELEASE 60%156827 107 -0.4848378 -1.7764715 0.0 0.006694384 0.858 5794 tags=58%, list=38%, signal=93% AMINO ACID ACTIVATION%GOBP%GO:0043038 AMINO ACID ACTIVATION%GOBP%GO:0043038 46 -0.5708577 -1.7753714 0.003533569 0.0067649134 0.861 4408 tags=52%, list=29%, signal=73% EUKARYOTIC TRANSLATION INITIATION%REACTOME%R-HSA-72613.3 EUKARYOTIC TRANSLATION INITIATION%REACTOME%R-HSA-72613.3 115 -0.4959831 -1.7733924 0.0 0.0069049024 0.87 5794 tags=60%, list=38%, signal=96% HALLMARK_IL6_JAK_STAT3_SIGNALING%MSIGDB_C2%HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING%MSIGDB_C2%HALLMARK_IL6_JAK_STAT3_SIGNALING 82 -0.5154438 -1.771385 0.0 0.0071138088 0.881 1659 tags=24%, list=11%, signal=27% DEATH RECEPTOR SIGNALLING%REACTOME DATABASE ID RELEASE 60%73887 DEATH RECEPTOR SIGNALLING%REACTOME DATABASE ID RELEASE 60%73887 47 -0.57223946 -1.7682639 0.0 0.0074315555 0.89 2600 tags=28%, list=17%, signal=33% MITOTIC PROPHASE%REACTOME DATABASE ID RELEASE 60%68875 MITOTIC PROPHASE%REACTOME DATABASE ID RELEASE 60%68875 99 -0.5027979 -1.7668573 0.0 0.0075308597 0.892 4337 tags=47%, list=29%, signal=66% SNRNA TRANSCRIPTION%GOBP%GO:0009301 SNRNA TRANSCRIPTION%GOBP%GO:0009301 64 -0.5439766 -1.765657 0.0 0.0076264953 0.897 3582 tags=39%, list=24%, signal=51% RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER%REACTOME%R-HSA-76071.2 RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER%REACTOME%R-HSA-76071.2 28 -0.6321588 -1.7654006 0.0 0.0076257894 0.897 3282 tags=39%, list=22%, signal=50% TRNA AMINOACYLATION%REACTOME DATABASE ID RELEASE 60%379724 TRNA AMINOACYLATION%REACTOME DATABASE ID RELEASE 60%379724 42 -0.5796522 -1.7653644 0.0 0.0076116067 0.898 4408 tags=52%, list=29%, signal=74% INTRACELLULAR PROTEIN TRANSPORT IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051708 INTRACELLULAR PROTEIN TRANSPORT IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051708 127 -0.47507316 -1.7645825 0.0 0.0076482743 0.902 3907 tags=43%, list=26%, signal=57% FANCONI ANEMIA PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FANCONI ANEMIA PATHWAY FANCONI ANEMIA PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FANCONI ANEMIA PATHWAY 44 -0.56854296 -1.7645432 0.0037593986 0.0076307324 0.902 1923 tags=39%, list=13%, signal=44% BIOCARTA_STATHMIN_PATHWAY%MSIGDB_C2%BIOCARTA_STATHMIN_PATHWAY BIOCARTA_STATHMIN_PATHWAY%MSIGDB_C2%BIOCARTA_STATHMIN_PATHWAY 16 -0.7359781 -1.7643543 0.0 0.0076434603 0.903 1474 tags=50%, list=10%, signal=55% REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002831 REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002831 71 -0.53144705 -1.7618682 0.0 0.007858737 0.91 3160 tags=38%, list=21%, signal=48% PROTEIN TARGETING TO ER%GOBP%GO:0045047 PROTEIN TARGETING TO ER%GOBP%GO:0045047 97 -0.49875647 -1.7613621 0.0 0.007881256 0.912 6240 tags=66%, list=41%, signal=111% PID_FANCONI_PATHWAY%MSIGDB_C2%PID_FANCONI_PATHWAY PID_FANCONI_PATHWAY%MSIGDB_C2%PID_FANCONI_PATHWAY 43 -0.5860989 -1.761165 0.0035211267 0.007880122 0.912 1923 tags=40%, list=13%, signal=45% SELENOCYSTEINE SYNTHESIS%REACTOME DATABASE ID RELEASE 60%2408557 SELENOCYSTEINE SYNTHESIS%REACTOME DATABASE ID RELEASE 60%2408557 88 -0.5016651 -1.760733 0.0 0.0079157865 0.913 6240 tags=68%, list=41%, signal=115% SYMBIONT INTRACELLULAR PROTEIN TRANSPORT IN HOST%GOBP%GO:0030581 SYMBIONT INTRACELLULAR PROTEIN TRANSPORT IN HOST%GOBP%GO:0030581 127 -0.47507316 -1.7606803 0.0 0.007897877 0.913 3907 tags=43%, list=26%, signal=57% TRANSLATIONAL INITIATION%GOBP%GO:0006413 TRANSLATIONAL INITIATION%GOBP%GO:0006413 116 -0.48511404 -1.7606335 0.0 0.007883449 0.913 5794 tags=59%, list=38%, signal=94% ESTABLISHMENT OF PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM%GOBP%GO:0072599 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM%GOBP%GO:0072599 101 -0.49468926 -1.7606025 0.0 0.007869025 0.913 6240 tags=63%, list=41%, signal=107% B-WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250924 B-WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250924 61 -0.5416847 -1.7599661 0.0 0.007904888 0.914 3762 tags=44%, list=25%, signal=59% POSITIVE REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001912 POSITIVE REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001912 19 -0.7103164 -1.7596866 0.005509642 0.007923449 0.914 2140 tags=47%, list=14%, signal=55% G0 AND EARLY G1%REACTOME DATABASE ID RELEASE 60%1538133 G0 AND EARLY G1%REACTOME DATABASE ID RELEASE 60%1538133 27 -0.65215075 -1.7590835 0.0 0.007998236 0.915 4477 tags=74%, list=29%, signal=105% GLYCOSYL COMPOUND METABOLIC PROCESS%GOBP%GO:1901657 GLYCOSYL COMPOUND METABOLIC PROCESS%GOBP%GO:1901657 83 -0.50245106 -1.7586763 0.0 0.00802957 0.915 1862 tags=27%, list=12%, signal=30% TRNA AMINOACYLATION%GOBP%GO:0043039 TRNA AMINOACYLATION%GOBP%GO:0043039 46 -0.5708577 -1.758063 0.0039525693 0.0080942 0.917 4408 tags=52%, list=29%, signal=73% REGULATION OF INTERFERON-BETA PRODUCTION%GOBP%GO:0032648 REGULATION OF INTERFERON-BETA PRODUCTION%GOBP%GO:0032648 35 -0.6156821 -1.7578422 0.0 0.008099221 0.917 2864 tags=37%, list=19%, signal=46% PID_HIV_NEF_PATHWAY%MSIGDB_C2%PID_HIV_NEF_PATHWAY PID_HIV_NEF_PATHWAY%MSIGDB_C2%PID_HIV_NEF_PATHWAY 34 -0.6017524 -1.7574447 0.0 0.008140495 0.92 1236 tags=24%, list=8%, signal=26% PROTEIN UBIQUITINATION%REACTOME DATABASE ID RELEASE 60%8852135 PROTEIN UBIQUITINATION%REACTOME DATABASE ID RELEASE 60%8852135 68 -0.5307617 -1.7568625 0.0 0.008207419 0.92 4440 tags=44%, list=29%, signal=62% NEGATIVE REGULATION OF INNATE IMMUNE RESPONSE%GOBP%GO:0045824 NEGATIVE REGULATION OF INNATE IMMUNE RESPONSE%GOBP%GO:0045824 24 -0.663497 -1.7567124 0.005449591 0.008222079 0.922 1055 tags=38%, list=7%, signal=40% IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE%GOBP%GO:0016064 IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE%GOBP%GO:0016064 22 -0.67439055 -1.7564944 0.0029850747 0.008236157 0.924 2195 tags=50%, list=14%, signal=58% PURINE NUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009127 PURINE NUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009127 43 -0.5639864 -1.7559093 0.0038910506 0.008305165 0.926 2619 tags=47%, list=17%, signal=56% CELLULAR RESPONSE TO TUMOR NECROSIS FACTOR%GOBP%GO:0071356 CELLULAR RESPONSE TO TUMOR NECROSIS FACTOR%GOBP%GO:0071356 156 -0.46988398 -1.7558922 0.0 0.008286952 0.926 2247 tags=36%, list=15%, signal=42% MHC CLASS II ANTIGEN PRESENTATION%REACTOME%R-HSA-2132295.3 MHC CLASS II ANTIGEN PRESENTATION%REACTOME%R-HSA-2132295.3 97 -0.502969 -1.753555 0.0 0.00854076 0.934 1186 tags=26%, list=8%, signal=28% EUKARYOTIC TRANSLATION TERMINATION%REACTOME DATABASE ID RELEASE 60%72764 EUKARYOTIC TRANSLATION TERMINATION%REACTOME DATABASE ID RELEASE 60%72764 89 -0.50623286 -1.7533386 0.0 0.008557338 0.934 6345 tags=69%, list=42%, signal=117% REGULATION OF NATURAL KILLER CELL MEDIATED CYTOTOXICITY%GOBP%GO:0042269 REGULATION OF NATURAL KILLER CELL MEDIATED CYTOTOXICITY%GOBP%GO:0042269 18 -0.69840163 -1.7521642 0.007556675 0.008670451 0.936 1879 tags=44%, list=12%, signal=51% DUAL INCISION IN GG-NER%REACTOME%R-HSA-5696400.1 DUAL INCISION IN GG-NER%REACTOME%R-HSA-5696400.1 41 -0.5680932 -1.7520438 0.0 0.008677651 0.937 4908 tags=66%, list=32%, signal=97% FC RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038093 FC RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038093 173 -0.45637023 -1.7513212 0.0 0.008735996 0.938 2313 tags=29%, list=15%, signal=34% MEIOTIC RECOMBINATION%REACTOME DATABASE ID RELEASE 60%912446 MEIOTIC RECOMBINATION%REACTOME DATABASE ID RELEASE 60%912446 54 -0.5477656 -1.751264 0.004115226 0.008726711 0.938 5973 tags=76%, list=39%, signal=125% CELLULAR RESPONSE TO HYPOXIA%GOBP%GO:0071456 CELLULAR RESPONSE TO HYPOXIA%GOBP%GO:0071456 122 -0.4817465 -1.7497468 0.0 0.008909143 0.941 2988 tags=35%, list=20%, signal=44% RECOMBINATIONAL REPAIR%GOBP%GO:0000725 RECOMBINATIONAL REPAIR%GOBP%GO:0000725 56 -0.5382918 -1.747968 0.0 0.009106293 0.945 4946 tags=57%, list=33%, signal=84% POSTREPLICATION REPAIR%GOBP%GO:0006301 POSTREPLICATION REPAIR%GOBP%GO:0006301 50 -0.5684794 -1.7478862 0.0037453184 0.009099533 0.945 3042 tags=40%, list=20%, signal=50% GENERAL TRANSCRIPTION REGULATION%PANTHER PATHWAY%P00023 GENERAL TRANSCRIPTION REGULATION%PANTHER PATHWAY%P00023 27 -0.6466134 -1.7475488 0.0 0.009124567 0.945 2884 tags=41%, list=19%, signal=50% INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS%REACTOME%R-HSA-176033.2 INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS%REACTOME%R-HSA-176033.2 31 -0.61105233 -1.7458616 0.0030487804 0.009307822 0.947 4293 tags=65%, list=28%, signal=90% RRNA MODIFICATION%GOBP%GO:0000154 RRNA MODIFICATION%GOBP%GO:0000154 22 -0.6560699 -1.7458534 0.0027173914 0.009297604 0.947 3920 tags=68%, list=26%, signal=92% GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT%REACTOME%R-HSA-72706.2 GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT%REACTOME%R-HSA-72706.2 108 -0.48511147 -1.7448845 0.0 0.00941362 0.949 5794 tags=58%, list=38%, signal=94% TRANSCRIPTION OF THE HIV GENOME%REACTOME%R-HSA-167172.2 TRANSCRIPTION OF THE HIV GENOME%REACTOME%R-HSA-167172.2 63 -0.5317818 -1.7447586 0.0 0.009418666 0.951 3782 tags=40%, list=25%, signal=53% NUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009142 NUCLEOSIDE TRIPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009142 38 -0.59775466 -1.7440746 0.0 0.009498824 0.952 3078 tags=61%, list=20%, signal=76% MULTI-ORGANISM INTRACELLULAR TRANSPORT%GOBP%GO:1902583 MULTI-ORGANISM INTRACELLULAR TRANSPORT%GOBP%GO:1902583 128 -0.4766278 -1.7425681 0.0 0.00971353 0.955 3907 tags=43%, list=26%, signal=57% HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA 32 -0.61950463 -1.7419823 0.0 0.009777363 0.956 1236 tags=25%, list=8%, signal=27% NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0009116 NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0009116 68 -0.5314981 -1.7419679 0.0 0.009756736 0.956 1471 tags=26%, list=10%, signal=29% APOPTOTIC MITOCHONDRIAL CHANGES%GOBP%GO:0008637 APOPTOTIC MITOCHONDRIAL CHANGES%GOBP%GO:0008637 40 -0.5760697 -1.7402792 0.0069204154 0.0099602165 0.96 3345 tags=43%, list=22%, signal=54% FATTY ACID CATABOLISM%REACTOME DATABASE ID RELEASE 60%8978919 FATTY ACID CATABOLISM%REACTOME DATABASE ID RELEASE 60%8978919 67 -0.52572125 -1.7398627 0.0 0.0100078825 0.962 5340 tags=60%, list=35%, signal=92% MITOCHONDRIAL RNA METABOLIC PROCESS%GOBP%GO:0000959 MITOCHONDRIAL RNA METABOLIC PROCESS%GOBP%GO:0000959 24 -0.6503371 -1.7397995 0.010899182 0.009993141 0.963 3158 tags=58%, list=21%, signal=74% GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG-NER%REACTOME%R-HSA-5696397.1 GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG-NER%REACTOME%R-HSA-5696397.1 25 -0.6445372 -1.7392194 0.0085227275 0.010055374 0.963 3042 tags=52%, list=20%, signal=65% PHOSPHORYLATION OF THE APC C%REACTOME DATABASE ID RELEASE 60%176412 PHOSPHORYLATION OF THE APC C%REACTOME DATABASE ID RELEASE 60%176412 18 -0.7132442 -1.739204 0.0054347827 0.01003758 0.963 2086 tags=44%, list=14%, signal=51% COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006613 COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006613 94 -0.48760393 -1.7391192 0.0 0.010035372 0.964 6240 tags=64%, list=41%, signal=108% MATURATION OF SSU-RRNA%GOBP%GO:0030490 MATURATION OF SSU-RRNA%GOBP%GO:0030490 44 -0.5790349 -1.7370076 0.0 0.010297169 0.97 4193 tags=59%, list=28%, signal=81% MITOCHONDRIAL TRANSMEMBRANE TRANSPORT%GOBP%GO:1990542 MITOCHONDRIAL TRANSMEMBRANE TRANSPORT%GOBP%GO:1990542 24 -0.6634468 -1.7348143 0.0030395137 0.01055413 0.972 1931 tags=42%, list=13%, signal=48% FORMATION OF TC-NER PRE-INCISION COMPLEX%REACTOME DATABASE ID RELEASE 60%6781823 FORMATION OF TC-NER PRE-INCISION COMPLEX%REACTOME DATABASE ID RELEASE 60%6781823 52 -0.54069257 -1.7342242 0.0 0.010611926 0.972 2892 tags=38%, list=19%, signal=47% RNA POLYMERASE I PROMOTER CLEARANCE%REACTOME%R-HSA-73854.2 RNA POLYMERASE I PROMOTER CLEARANCE%REACTOME%R-HSA-73854.2 80 -0.5101145 -1.733943 0.0 0.010608194 0.972 3782 tags=41%, list=25%, signal=55% BIOCARTA_IL12_PATHWAY%MSIGDB_C2%BIOCARTA_IL12_PATHWAY BIOCARTA_IL12_PATHWAY%MSIGDB_C2%BIOCARTA_IL12_PATHWAY 19 -0.67020816 -1.73264 0.0054054055 0.010805652 0.974 1714 tags=53%, list=11%, signal=59% ASYMMETRIC LOCALIZATION OF PCP PROTEINS%REACTOME%R-HSA-4608870.1 ASYMMETRIC LOCALIZATION OF PCP PROTEINS%REACTOME%R-HSA-4608870.1 62 -0.5258654 -1.7322576 0.0 0.010844694 0.975 1584 tags=37%, list=10%, signal=41% MULTI-ORGANISM CELLULAR LOCALIZATION%GOBP%GO:1902581 MULTI-ORGANISM CELLULAR LOCALIZATION%GOBP%GO:1902581 128 -0.4766278 -1.7321111 0.0 0.0108404495 0.975 3907 tags=43%, list=26%, signal=57% NUCLEAR IMPORT%GOBP%GO:0051170 NUCLEAR IMPORT%GOBP%GO:0051170 24 -0.6354127 -1.7320243 0.002762431 0.010824245 0.975 2043 tags=50%, list=13%, signal=58% VIRAL MRNA TRANSLATION%REACTOME%R-HSA-192823.2 VIRAL MRNA TRANSLATION%REACTOME%R-HSA-192823.2 85 -0.4976748 -1.7306231 0.0 0.011023251 0.977 6240 tags=68%, list=41%, signal=115% CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION%REACTOME DATABASE ID RELEASE 60%69273 CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION%REACTOME DATABASE ID RELEASE 60%69273 25 -0.6413169 -1.7303975 0.0056657223 0.011021802 0.977 2141 tags=36%, list=14%, signal=42% NON-RECOMBINATIONAL REPAIR%GOBP%GO:0000726 NON-RECOMBINATIONAL REPAIR%GOBP%GO:0000726 58 -0.53259915 -1.7291846 0.0 0.011192466 0.977 4060 tags=48%, list=27%, signal=66% LIGAND-DEPENDENT CASPASE ACTIVATION%REACTOME%R-HSA-140534.3 LIGAND-DEPENDENT CASPASE ACTIVATION%REACTOME%R-HSA-140534.3 16 -0.72974014 -1.72681 0.0 0.011466315 0.978 615 tags=25%, list=4%, signal=26% PACKAGING OF TELOMERE ENDS%REACTOME DATABASE ID RELEASE 60%171306 PACKAGING OF TELOMERE ENDS%REACTOME DATABASE ID RELEASE 60%171306 29 -0.6229677 -1.7255131 0.0 0.011701131 0.98 3655 tags=55%, list=24%, signal=72% PROTEIN MONOUBIQUITINATION%GOBP%GO:0006513 PROTEIN MONOUBIQUITINATION%GOBP%GO:0006513 45 -0.5498944 -1.7247614 0.0 0.011803739 0.98 3071 tags=27%, list=20%, signal=33% 3' -UTR-MEDIATED TRANSLATIONAL REGULATION%REACTOME%R-HSA-157279.2 3' -UTR-MEDIATED TRANSLATIONAL REGULATION%REACTOME%R-HSA-157279.2 107 -0.4848378 -1.7245406 0.0 0.011800764 0.98 5794 tags=58%, list=38%, signal=93% GUANOSINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:1901068 GUANOSINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:1901068 22 -0.66782856 -1.7245312 0.0 0.011776973 0.98 1471 tags=27%, list=10%, signal=30% NEGATIVE REGULATION OF DEFENSE RESPONSE TO VIRUS%GOBP%GO:0050687 NEGATIVE REGULATION OF DEFENSE RESPONSE TO VIRUS%GOBP%GO:0050687 17 -0.6990676 -1.7242767 0.0053475937 0.011800759 0.98 419 tags=24%, list=3%, signal=24% DOWNSTREAM SIGNALING IN NAIVE CD8+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%DOWNSTREAM SIGNALING IN NAIVE CD8+ T CELLS DOWNSTREAM SIGNALING IN NAIVE CD8+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%DOWNSTREAM SIGNALING IN NAIVE CD8+ T CELLS 50 -0.55218554 -1.7240531 0.0 0.011815332 0.98 1942 tags=36%, list=13%, signal=41% VIRAL GENE EXPRESSION%GOBP%GO:0019080 VIRAL GENE EXPRESSION%GOBP%GO:0019080 119 -0.47627884 -1.7231997 0.0 0.0119185615 0.981 5794 tags=57%, list=38%, signal=92% DEOXYRIBONUCLEOTIDE CATABOLIC PROCESS%GOBP%GO:0009264 DEOXYRIBONUCLEOTIDE CATABOLIC PROCESS%GOBP%GO:0009264 17 -0.70464045 -1.721368 0.007874016 0.012146939 0.984 2244 tags=53%, list=15%, signal=62% MRNA TRANSPORT%GOBP%GO:0051028 MRNA TRANSPORT%GOBP%GO:0051028 90 -0.49099547 -1.7206839 0.0 0.012228277 0.984 4293 tags=43%, list=28%, signal=60% PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009168 PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0009168 43 -0.5639864 -1.720051 0.0068728523 0.012312851 0.985 2619 tags=47%, list=17%, signal=56% REGULATION OF NATURAL KILLER CELL MEDIATED IMMUNITY%GOBP%GO:0002715 REGULATION OF NATURAL KILLER CELL MEDIATED IMMUNITY%GOBP%GO:0002715 18 -0.69840163 -1.7199292 0.0026809652 0.012320458 0.985 1879 tags=44%, list=12%, signal=51% DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0006354 DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0006354 99 -0.48829633 -1.7191395 0.0 0.012453494 0.985 2861 tags=29%, list=19%, signal=36% DOUBLE-STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION%GOBP%GO:0000724 DOUBLE-STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION%GOBP%GO:0000724 56 -0.5382918 -1.7187706 0.0 0.012472489 0.985 4946 tags=57%, list=33%, signal=84% APC-CDC20 MEDIATED DEGRADATION OF NEK2A%REACTOME DATABASE ID RELEASE 60%179409 APC-CDC20 MEDIATED DEGRADATION OF NEK2A%REACTOME DATABASE ID RELEASE 60%179409 24 -0.6442495 -1.7180412 0.0057142857 0.012559146 0.985 2247 tags=42%, list=15%, signal=49% REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002706 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002706 62 -0.52802783 -1.71705 0.0 0.012712947 0.985 2140 tags=34%, list=14%, signal=39% POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002708 POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002708 40 -0.57140046 -1.7152169 0.0 0.013020427 0.988 2140 tags=33%, list=14%, signal=38% APC C:CDC20 MEDIATED DEGRADATION OF CYCLIN B%REACTOME DATABASE ID RELEASE 60%174048 APC C:CDC20 MEDIATED DEGRADATION OF CYCLIN B%REACTOME DATABASE ID RELEASE 60%174048 22 -0.65405095 -1.7149723 0.002762431 0.013024257 0.988 2247 tags=41%, list=15%, signal=48% RNA MODIFICATION%GOBP%GO:0009451 RNA MODIFICATION%GOBP%GO:0009451 83 -0.5039139 -1.7145684 0.0 0.013053682 0.988 4122 tags=52%, list=27%, signal=71% PID_PLK1_PATHWAY%MSIGDB_C2%PID_PLK1_PATHWAY PID_PLK1_PATHWAY%MSIGDB_C2%PID_PLK1_PATHWAY 43 -0.5708166 -1.7145605 0.0032573289 0.013030949 0.988 3279 tags=49%, list=22%, signal=62% RIBOSOMAL LARGE SUBUNIT BIOGENESIS%GOBP%GO:0042273 RIBOSOMAL LARGE SUBUNIT BIOGENESIS%GOBP%GO:0042273 55 -0.5275174 -1.7131826 0.003968254 0.013224543 0.989 4958 tags=51%, list=33%, signal=75% BIOCARTA_CASPASE_PATHWAY%MSIGDB_C2%BIOCARTA_CASPASE_PATHWAY BIOCARTA_CASPASE_PATHWAY%MSIGDB_C2%BIOCARTA_CASPASE_PATHWAY 23 -0.65419346 -1.7129039 0.0056980057 0.013247869 0.99 3152 tags=48%, list=21%, signal=60% DEOXYRIBOSE PHOSPHATE CATABOLIC PROCESS%GOBP%GO:0046386 DEOXYRIBOSE PHOSPHATE CATABOLIC PROCESS%GOBP%GO:0046386 16 -0.7162286 -1.7124014 0.0072289156 0.01330029 0.99 2244 tags=56%, list=15%, signal=66% MITOTIC SPINDLE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69618 MITOTIC SPINDLE CHECKPOINT%REACTOME DATABASE ID RELEASE 60%69618 20 -0.6721111 -1.7112745 0.007751938 0.013438558 0.99 3357 tags=50%, list=22%, signal=64% DNA DAMAGE RECOGNITION IN GG-NER%REACTOME%R-HSA-5696394.1 DNA DAMAGE RECOGNITION IN GG-NER%REACTOME%R-HSA-5696394.1 38 -0.57193935 -1.7110962 0.0 0.013423775 0.99 4550 tags=63%, list=30%, signal=90% DNA REPLICATION INITIATION%GOBP%GO:0006270 DNA REPLICATION INITIATION%GOBP%GO:0006270 18 -0.6873021 -1.7109504 0.005449591 0.013414873 0.99 2352 tags=61%, list=15%, signal=72% RNA POLYMERASE II PRE-TRANSCRIPTION EVENTS%REACTOME%R-HSA-674695.2 RNA POLYMERASE II PRE-TRANSCRIPTION EVENTS%REACTOME%R-HSA-674695.2 74 -0.49837765 -1.7107904 0.0 0.013420083 0.99 2861 tags=32%, list=19%, signal=40% MITOCHONDRIAL FATTY ACID BETA-OXIDATION%REACTOME DATABASE ID RELEASE 60%77289 MITOCHONDRIAL FATTY ACID BETA-OXIDATION%REACTOME DATABASE ID RELEASE 60%77289 32 -0.60047394 -1.7104932 0.009868421 0.013453979 0.99 3033 tags=44%, list=20%, signal=55% REV-MEDIATED NUCLEAR EXPORT OF HIV RNA%REACTOME%R-HSA-165054.2 REV-MEDIATED NUCLEAR EXPORT OF HIV RNA%REACTOME%R-HSA-165054.2 29 -0.6091881 -1.7072712 0.002915452 0.01393035 0.992 4293 tags=66%, list=28%, signal=91% PURINE NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0042278 PURINE NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0042278 36 -0.5831548 -1.70532 0.0 0.014252549 0.992 4927 tags=50%, list=32%, signal=74% CELLULAR RESPONSE TO DECREASED OXYGEN LEVELS%GOBP%GO:0036294 CELLULAR RESPONSE TO DECREASED OXYGEN LEVELS%GOBP%GO:0036294 125 -0.4729987 -1.7049258 0.0 0.014298736 0.992 2988 tags=34%, list=20%, signal=42% POSITIVE REGULATION OF T CELL ACTIVATION%GOBP%GO:0050870 POSITIVE REGULATION OF T CELL ACTIVATION%GOBP%GO:0050870 141 -0.45235032 -1.7027861 0.0 0.014646477 0.993 2309 tags=40%, list=15%, signal=46% DNA MODIFICATION%GOBP%GO:0006304 DNA MODIFICATION%GOBP%GO:0006304 55 -0.5309251 -1.702709 0.004048583 0.014626877 0.993 1691 tags=27%, list=11%, signal=31% POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250913 POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%5250913 76 -0.48880005 -1.7015986 0.004608295 0.014785131 0.993 3762 tags=38%, list=25%, signal=50% RIBOSOME ASSEMBLY%GOBP%GO:0042255 RIBOSOME ASSEMBLY%GOBP%GO:0042255 45 -0.54501015 -1.7014891 0.003164557 0.014765728 0.993 3800 tags=40%, list=25%, signal=53% POSITIVE REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051984 POSITIVE REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051984 21 -0.6638472 -1.6993268 0.002967359 0.015083315 0.995 2423 tags=33%, list=16%, signal=40% INACTIVATION OF APC C VIA DIRECT INHIBITION OF THE APC C COMPLEX%REACTOME DATABASE ID RELEASE 60%141430 INACTIVATION OF APC C VIA DIRECT INHIBITION OF THE APC C COMPLEX%REACTOME DATABASE ID RELEASE 60%141430 19 -0.6747791 -1.6986779 0.002739726 0.015178309 0.995 3357 tags=53%, list=22%, signal=67% VIRAL MESSENGER RNA SYNTHESIS%REACTOME DATABASE ID RELEASE 60%168325 VIRAL MESSENGER RNA SYNTHESIS%REACTOME DATABASE ID RELEASE 60%168325 38 -0.57663685 -1.698436 0.0068728523 0.015205782 0.995 4293 tags=58%, list=28%, signal=80% REGULATION OF INTERFERON-ALPHA PRODUCTION%GOBP%GO:0032647 REGULATION OF INTERFERON-ALPHA PRODUCTION%GOBP%GO:0032647 19 -0.688549 -1.6970402 0.0051150895 0.015453514 0.995 2055 tags=42%, list=14%, signal=49% REGULATION OF CELLULAR KETONE METABOLIC PROCESS%GOBP%GO:0010565 REGULATION OF CELLULAR KETONE METABOLIC PROCESS%GOBP%GO:0010565 122 -0.46151942 -1.696565 0.0 0.015511157 0.995 2166 tags=33%, list=14%, signal=38% REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903037 REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903037 199 -0.44284424 -1.6964095 0.0 0.015507075 0.995 2309 tags=39%, list=15%, signal=46% TRNA MODIFICATION%GOBP%GO:0006400 TRNA MODIFICATION%GOBP%GO:0006400 47 -0.5441629 -1.6953765 0.003816794 0.01566437 0.996 5940 tags=74%, list=39%, signal=122% REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002819 REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002819 72 -0.5028443 -1.6948694 0.0 0.015735026 0.996 2140 tags=32%, list=14%, signal=37% MATURATION OF 5.8S RRNA%GOBP%GO:0000460 MATURATION OF 5.8S RRNA%GOBP%GO:0000460 26 -0.6267427 -1.6939563 0.006060606 0.015874645 0.996 4958 tags=62%, list=33%, signal=91% REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034121 REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034121 39 -0.56821704 -1.6917479 0.0 0.016296454 0.997 2327 tags=38%, list=15%, signal=45% MRNA 3'-END PROCESSING%REACTOME DATABASE ID RELEASE 60%72187 MRNA 3'-END PROCESSING%REACTOME DATABASE ID RELEASE 60%72187 43 -0.5555981 -1.6908351 0.0033557047 0.016461754 0.998 3885 tags=44%, list=26%, signal=59% PEPTIDE CHAIN ELONGATION%REACTOME DATABASE ID RELEASE 60%156902 PEPTIDE CHAIN ELONGATION%REACTOME DATABASE ID RELEASE 60%156902 85 -0.4868531 -1.6887125 0.0 0.016788222 0.998 6240 tags=67%, list=41%, signal=113% FATTY ACID CATABOLIC PROCESS%GOBP%GO:0009062 FATTY ACID CATABOLIC PROCESS%GOBP%GO:0009062 63 -0.5096148 -1.6881334 0.0 0.016856065 0.998 3144 tags=41%, list=21%, signal=52% MRNA EXPORT FROM NUCLEUS%GOBP%GO:0006406 MRNA EXPORT FROM NUCLEUS%GOBP%GO:0006406 87 -0.49084654 -1.6880226 0.0 0.016833156 0.998 4293 tags=44%, list=28%, signal=61% POLO-LIKE KINASE MEDIATED EVENTS%REACTOME%R-HSA-156711.2 POLO-LIKE KINASE MEDIATED EVENTS%REACTOME%R-HSA-156711.2 16 -0.6798982 -1.6875683 0.0123152705 0.016894918 0.998 2858 tags=56%, list=19%, signal=69% INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS%REACTOME DATABASE ID RELEASE 60%141405 INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS%REACTOME DATABASE ID RELEASE 60%141405 19 -0.6747791 -1.685087 0.002994012 0.017274437 0.998 3357 tags=53%, list=22%, signal=67% RNA POLYMERASE III TRANSCRIPTION INITIATION%REACTOME%R-HSA-76046.2 RNA POLYMERASE III TRANSCRIPTION INITIATION%REACTOME%R-HSA-76046.2 36 -0.5706053 -1.6849827 0.0062695923 0.017261902 0.998 3282 tags=36%, list=22%, signal=46% FORMATION OF A POOL OF FREE 40S SUBUNITS%REACTOME DATABASE ID RELEASE 60%72689 FORMATION OF A POOL OF FREE 40S SUBUNITS%REACTOME DATABASE ID RELEASE 60%72689 97 -0.49400076 -1.684665 0.0 0.01730111 0.998 6240 tags=65%, list=41%, signal=109% PID_CD8_TCR_PATHWAY%MSIGDB_C2%PID_CD8_TCR_PATHWAY PID_CD8_TCR_PATHWAY%MSIGDB_C2%PID_CD8_TCR_PATHWAY 52 -0.5276666 -1.6837133 0.003787879 0.017529765 0.998 1950 tags=38%, list=13%, signal=44% SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%427359 SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 60%427359 39 -0.5672003 -1.6834782 0.0066006603 0.017538525 0.998 3655 tags=46%, list=24%, signal=61% HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME DATABASE ID RELEASE 60%5693579 HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME DATABASE ID RELEASE 60%5693579 38 -0.5700871 -1.6832232 0.010714286 0.017549876 0.998 5059 tags=74%, list=33%, signal=110% NUCLEAR TRANSPORT%GOBP%GO:0051169 NUCLEAR TRANSPORT%GOBP%GO:0051169 158 -0.44594815 -1.6831315 0.0 0.017531713 0.998 3907 tags=44%, list=26%, signal=58% PLK1 SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%PLK1 SIGNALING EVENTS PLK1 SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%PLK1 SIGNALING EVENTS 43 -0.55934024 -1.6826087 0.0035842294 0.01761313 0.998 3079 tags=47%, list=20%, signal=58% REGULATION OF TRANSCRIPTION INVOLVED IN G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000083 REGULATION OF TRANSCRIPTION INVOLVED IN G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000083 23 -0.62860984 -1.6822221 0.0057803467 0.017648702 0.998 3539 tags=61%, list=23%, signal=79% PROCESSIVE SYNTHESIS ON THE LAGGING STRAND%REACTOME%R-HSA-69183.2 PROCESSIVE SYNTHESIS ON THE LAGGING STRAND%REACTOME%R-HSA-69183.2 15 -0.72950387 -1.6820844 0.011904762 0.017659476 0.998 2567 tags=67%, list=17%, signal=80% REGULATION OF CELL KILLING%GOBP%GO:0031341 REGULATION OF CELL KILLING%GOBP%GO:0031341 36 -0.5844532 -1.6819268 0.0067340066 0.01764863 0.998 2140 tags=39%, list=14%, signal=45% POST-ELONGATION PROCESSING OF INTRON-CONTAINING PRE-MRNA%REACTOME DATABASE ID RELEASE 60%112296 POST-ELONGATION PROCESSING OF INTRON-CONTAINING PRE-MRNA%REACTOME DATABASE ID RELEASE 60%112296 43 -0.5555981 -1.6807905 0.0034013605 0.017849378 0.998 3885 tags=44%, list=26%, signal=59% RNA POLYMERASE I PROMOTER OPENING%REACTOME DATABASE ID RELEASE 60%73728 RNA POLYMERASE I PROMOTER OPENING%REACTOME DATABASE ID RELEASE 60%73728 34 -0.58012927 -1.6796291 0.00949367 0.018046014 0.998 5479 tags=74%, list=36%, signal=115% MRNA-CONTAINING RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071427 MRNA-CONTAINING RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071427 87 -0.49084654 -1.6795518 0.010989011 0.018037356 0.998 4293 tags=44%, list=28%, signal=61% E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS%REACTOME%R-HSA-8866654.2 E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS%REACTOME%R-HSA-8866654.2 49 -0.52916884 -1.6789606 0.0 0.018118795 0.998 4440 tags=47%, list=29%, signal=66% SRP-DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006614 SRP-DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006614 88 -0.48407137 -1.6771147 0.0 0.018465506 0.998 6240 tags=65%, list=41%, signal=109% RNA POLYMERASE III CHAIN ELONGATION%REACTOME%R-HSA-73780.2 RNA POLYMERASE III CHAIN ELONGATION%REACTOME%R-HSA-73780.2 18 -0.6806633 -1.6769533 0.008196721 0.018461594 0.998 2682 tags=44%, list=18%, signal=54% DNA REPLICATION%PANTHER PATHWAY%P00017 DNA REPLICATION%PANTHER PATHWAY%P00017 17 -0.6800452 -1.6763021 0.007853403 0.018573862 0.998 3539 tags=65%, list=23%, signal=84% ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR (ANDROGEN RECEPTOR) REGULATED GENES KLK2 AND KLK3%REACTOME DATABASE ID RELEASE 60%5625886 ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR (ANDROGEN RECEPTOR) REGULATED GENES KLK2 AND KLK3%REACTOME DATABASE ID RELEASE 60%5625886 36 -0.5739468 -1.6762003 0.0036630037 0.018553823 0.998 5880 tags=75%, list=39%, signal=122% CELL KILLING%GOBP%GO:0001906 CELL KILLING%GOBP%GO:0001906 30 -0.58946073 -1.6720139 0.006329114 0.019397013 0.999 3698 tags=50%, list=24%, signal=66% REGULATION OF T CELL MEDIATED IMMUNITY%GOBP%GO:0002709 REGULATION OF T CELL MEDIATED IMMUNITY%GOBP%GO:0002709 36 -0.5719047 -1.671818 0.010989011 0.019409226 0.999 2140 tags=36%, list=14%, signal=42% PID_CD8_TCR_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_CD8_TCR_DOWNSTREAM_PATHWAY PID_CD8_TCR_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_CD8_TCR_DOWNSTREAM_PATHWAY 50 -0.5381862 -1.6707517 0.010309278 0.019621586 0.999 1942 tags=36%, list=13%, signal=41% CELLULAR RESPONSE TO OXYGEN LEVELS%GOBP%GO:0071453 CELLULAR RESPONSE TO OXYGEN LEVELS%GOBP%GO:0071453 129 -0.45356447 -1.6706325 0.0 0.019612905 0.999 2988 tags=33%, list=20%, signal=41% POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002824 POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002824 40 -0.56316596 -1.6682793 0.0 0.020129573 0.999 2140 tags=35%, list=14%, signal=41% SYNTHESIS OF ACTIVE UBIQUITIN: ROLES OF E1 AND E2 ENZYMES%REACTOME%R-HSA-8866652.2 SYNTHESIS OF ACTIVE UBIQUITIN: ROLES OF E1 AND E2 ENZYMES%REACTOME%R-HSA-8866652.2 29 -0.5953848 -1.6679337 0.0061919503 0.02017031 0.999 5535 tags=66%, list=36%, signal=103% REGULATION OF T CELL MEDIATED CYTOTOXICITY%GOBP%GO:0001914 REGULATION OF T CELL MEDIATED CYTOTOXICITY%GOBP%GO:0001914 15 -0.6901591 -1.6676021 0.012437811 0.020223996 0.999 2140 tags=53%, list=14%, signal=62% MRNA 3'-END PROCESSING%GOBP%GO:0031124 MRNA 3'-END PROCESSING%GOBP%GO:0031124 60 -0.5125927 -1.6675586 0.0 0.020193588 0.999 3885 tags=43%, list=26%, signal=58% NATURAL KILLER CELL ACTIVATION%GOBP%GO:0030101 NATURAL KILLER CELL ACTIVATION%GOBP%GO:0030101 15 -0.7201486 -1.6674823 0.004950495 0.020170953 0.999 1296 tags=40%, list=9%, signal=44% REGULATION OF MYELOID LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002886 REGULATION OF MYELOID LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002886 22 -0.6505805 -1.667411 0.0026666666 0.020148538 0.999 2167 tags=36%, list=14%, signal=42% VPR-MEDIATED NUCLEAR IMPORT OF PICS%REACTOME DATABASE ID RELEASE 60%180910 VPR-MEDIATED NUCLEAR IMPORT OF PICS%REACTOME DATABASE ID RELEASE 60%180910 28 -0.5967281 -1.6671618 0.012012012 0.020190999 0.999 4293 tags=61%, list=28%, signal=84% NONSENSE MEDIATED DECAY (NMD) ENHANCED BY THE EXON JUNCTION COMPLEX (EJC)%REACTOME DATABASE ID RELEASE 60%975957 NONSENSE MEDIATED DECAY (NMD) ENHANCED BY THE EXON JUNCTION COMPLEX (EJC)%REACTOME DATABASE ID RELEASE 60%975957 109 -0.4614989 -1.6671091 0.0 0.020160861 0.999 6240 tags=63%, list=41%, signal=107% HEDGEHOG 'ON' STATE%REACTOME%R-HSA-5632684.1 HEDGEHOG 'ON' STATE%REACTOME%R-HSA-5632684.1 80 -0.48835787 -1.6641785 0.0 0.02081751 0.999 2247 tags=38%, list=15%, signal=44% IL12 SIGNALING MEDIATED BY STAT4%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL12 SIGNALING MEDIATED BY STAT4 IL12 SIGNALING MEDIATED BY STAT4%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL12 SIGNALING MEDIATED BY STAT4 26 -0.61714476 -1.6639256 0.00625 0.020840747 0.999 1714 tags=46%, list=11%, signal=52% REGULATION OF MAST CELL DEGRANULATION%GOBP%GO:0043304 REGULATION OF MAST CELL DEGRANULATION%GOBP%GO:0043304 19 -0.65048325 -1.6626866 0.021621622 0.021107797 0.999 3458 tags=47%, list=23%, signal=61% REGULATION OF TYPE I INTERFERON-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060338 REGULATION OF TYPE I INTERFERON-MEDIATED SIGNALING PATHWAY%GOBP%GO:0060338 22 -0.6361738 -1.6626277 0.005235602 0.021081276 0.999 512 tags=23%, list=3%, signal=23% TRNA AMINOACYLATION FOR PROTEIN TRANSLATION%GOBP%GO:0006418 TRNA AMINOACYLATION FOR PROTEIN TRANSLATION%GOBP%GO:0006418 44 -0.55937856 -1.6621392 0.0036231885 0.021170087 0.999 4408 tags=50%, list=29%, signal=70% PROTEIN K11-LINKED UBIQUITINATION%GOBP%GO:0070979 PROTEIN K11-LINKED UBIQUITINATION%GOBP%GO:0070979 28 -0.591894 -1.6596948 0.009146341 0.02170154 0.999 2086 tags=29%, list=14%, signal=33% POSITIVE REGULATION OF LYMPHOCYTE ACTIVATION%GOBP%GO:0051251 POSITIVE REGULATION OF LYMPHOCYTE ACTIVATION%GOBP%GO:0051251 171 -0.43014544 -1.6589515 0.0 0.021799736 0.999 2309 tags=37%, list=15%, signal=43% DNA LIGATION%GOBP%GO:0006266 DNA LIGATION%GOBP%GO:0006266 20 -0.6536684 -1.6586112 0.0057142857 0.021836026 0.999 1837 tags=40%, list=12%, signal=45% ANTIMICROBIAL HUMORAL IMMUNE RESPONSE MEDIATED BY ANTIMICROBIAL PEPTIDE%GOBP%GO:0061844 ANTIMICROBIAL HUMORAL IMMUNE RESPONSE MEDIATED BY ANTIMICROBIAL PEPTIDE%GOBP%GO:0061844 20 -0.65008086 -1.6584558 0.019830028 0.021824092 0.999 3319 tags=55%, list=22%, signal=70% NUCLEOTIDE-EXCISION REPAIR, DNA INCISION%GOBP%GO:0033683 NUCLEOTIDE-EXCISION REPAIR, DNA INCISION%GOBP%GO:0033683 38 -0.57221985 -1.6579314 0.006024096 0.021905877 0.999 4550 tags=61%, list=30%, signal=86% TRANSLESION SYNTHESIS BY POLH%REACTOME DATABASE ID RELEASE 60%110320 TRANSLESION SYNTHESIS BY POLH%REACTOME DATABASE ID RELEASE 60%110320 18 -0.6634045 -1.657915 0.012626262 0.021870915 0.999 3290 tags=61%, list=22%, signal=78% TRNA CHARGING%HUMANCYC%TRNA-CHARGING-PWY TRNA CHARGING%HUMANCYC%TRNA-CHARGING-PWY 37 -0.56054974 -1.6577246 0.006451613 0.02187388 0.999 4408 tags=49%, list=29%, signal=68% NUCLEOTIDE-EXCISION REPAIR, DNA INCISION, 5'-TO LESION%GOBP%GO:0006296 NUCLEOTIDE-EXCISION REPAIR, DNA INCISION, 5'-TO LESION%GOBP%GO:0006296 37 -0.5658746 -1.6576966 0.0069204154 0.021844083 0.999 4550 tags=59%, list=30%, signal=85% PYRIMIDINE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0006220 PYRIMIDINE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0006220 22 -0.64467216 -1.6566864 0.008498584 0.022020731 0.999 1691 tags=55%, list=11%, signal=61% MRNA DECAY BY 5' TO 3' EXORIBONUCLEASE%REACTOME%R-HSA-430039.1 MRNA DECAY BY 5' TO 3' EXORIBONUCLEASE%REACTOME%R-HSA-430039.1 15 -0.7042469 -1.6539488 0.009779952 0.022645427 0.999 1587 tags=40%, list=10%, signal=45% PRESYNAPTIC PHASE OF HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME DATABASE ID RELEASE 60%5693616 PRESYNAPTIC PHASE OF HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME DATABASE ID RELEASE 60%5693616 35 -0.55731124 -1.6535717 0.006993007 0.022704922 0.999 5059 tags=71%, list=33%, signal=107% RNA-DEPENDENT DNA BIOSYNTHETIC PROCESS%GOBP%GO:0006278 RNA-DEPENDENT DNA BIOSYNTHETIC PROCESS%GOBP%GO:0006278 18 -0.67505217 -1.6521645 0.005167959 0.023006411 0.999 3894 tags=56%, list=26%, signal=75% INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS%REACTOME%R-HSA-177243.2 INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS%REACTOME%R-HSA-177243.2 31 -0.59674144 -1.651475 0.012820513 0.023152461 0.999 4293 tags=61%, list=28%, signal=85% TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0007004 TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0007004 17 -0.66975087 -1.6508174 0.009975063 0.023290375 0.999 3894 tags=53%, list=26%, signal=71% NUCLEOCYTOPLASMIC TRANSPORT%GOBP%GO:0006913 NUCLEOCYTOPLASMIC TRANSPORT%GOBP%GO:0006913 155 -0.43423697 -1.6506147 0.0 0.023290763 0.999 3907 tags=43%, list=26%, signal=57% PIWI-INTERACTING RNA (PIRNA) BIOGENESIS%REACTOME%R-HSA-5601884.1 PIWI-INTERACTING RNA (PIRNA) BIOGENESIS%REACTOME%R-HSA-5601884.1 20 -0.6403838 -1.6499438 0.011730205 0.02343079 0.999 4639 tags=65%, list=30%, signal=93% CHROMATIN SILENCING%GOBP%GO:0006342 CHROMATIN SILENCING%GOBP%GO:0006342 51 -0.51528883 -1.6475489 0.0 0.024040746 0.999 4337 tags=47%, list=29%, signal=66% REGULATION OF MAST CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0033006 REGULATION OF MAST CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0033006 19 -0.65048325 -1.6473898 0.01511335 0.024047706 0.999 3458 tags=47%, list=23%, signal=61% DOUBLE-STRAND BREAK REPAIR VIA NONHOMOLOGOUS END JOINING%GOBP%GO:0006303 DOUBLE-STRAND BREAK REPAIR VIA NONHOMOLOGOUS END JOINING%GOBP%GO:0006303 55 -0.5128987 -1.6472164 0.0 0.024051925 1.0 4060 tags=47%, list=27%, signal=64% NS1 MEDIATED EFFECTS ON HOST PATHWAYS%REACTOME DATABASE ID RELEASE 60%168276 NS1 MEDIATED EFFECTS ON HOST PATHWAYS%REACTOME DATABASE ID RELEASE 60%168276 34 -0.5754196 -1.6462568 0.0 0.024256296 1.0 4293 tags=56%, list=28%, signal=78% NONSENSE-MEDIATED DECAY (NMD)%REACTOME%R-HSA-927802.2 NONSENSE-MEDIATED DECAY (NMD)%REACTOME%R-HSA-927802.2 109 -0.4614989 -1.6461496 0.0 0.024248404 1.0 6240 tags=63%, list=41%, signal=107% NEGATIVE REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0045814 NEGATIVE REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0045814 69 -0.48997506 -1.6459184 0.0 0.024284257 1.0 3326 tags=39%, list=22%, signal=50% HOST INTERACTIONS WITH INFLUENZA FACTORS%REACTOME DATABASE ID RELEASE 60%168253 HOST INTERACTIONS WITH INFLUENZA FACTORS%REACTOME DATABASE ID RELEASE 60%168253 36 -0.563753 -1.6449292 0.0033783785 0.024528373 1.0 4293 tags=56%, list=28%, signal=77% COFACTOR BIOSYNTHETIC PROCESS%GOBP%GO:0051188 COFACTOR BIOSYNTHETIC PROCESS%GOBP%GO:0051188 120 -0.44584838 -1.644395 0.0 0.02463249 1.0 3855 tags=48%, list=25%, signal=63% PROCESSING OF CAPPED INTRONLESS PRE-MRNA%REACTOME DATABASE ID RELEASE 60%75067 PROCESSING OF CAPPED INTRONLESS PRE-MRNA%REACTOME DATABASE ID RELEASE 60%75067 28 -0.58964324 -1.6404364 0.0028328612 0.025598874 1.0 2652 tags=39%, list=17%, signal=47% REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070663 REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070663 107 -0.45064354 -1.6382776 0.0 0.02621257 1.0 2257 tags=36%, list=15%, signal=41% REGULATION OF T CELL APOPTOTIC PROCESS%GOBP%GO:0070232 REGULATION OF T CELL APOPTOTIC PROCESS%GOBP%GO:0070232 17 -0.68254274 -1.6382223 0.007853403 0.026191268 1.0 1315 tags=59%, list=9%, signal=64% TCR SIGNALING IN NAIVE CD8+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TCR SIGNALING IN NAIVE CD8+ T CELLS TCR SIGNALING IN NAIVE CD8+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TCR SIGNALING IN NAIVE CD8+ T CELLS 52 -0.5276667 -1.6374139 0.0072202166 0.026327265 1.0 1950 tags=38%, list=13%, signal=44% SPLICEOSOMAL COMPLEX ASSEMBLY%GOBP%GO:0000245 SPLICEOSOMAL COMPLEX ASSEMBLY%GOBP%GO:0000245 38 -0.54552996 -1.6369816 0.012903226 0.02637634 1.0 4260 tags=47%, list=28%, signal=66% REGULATED NECROSIS%REACTOME%R-HSA-5218859.1 REGULATED NECROSIS%REACTOME%R-HSA-5218859.1 15 -0.6960526 -1.6367325 0.0076726344 0.026422985 1.0 1236 tags=33%, list=8%, signal=36% SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS%REACTOME DATABASE ID RELEASE 60%3108214 SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS%REACTOME DATABASE ID RELEASE 60%3108214 69 -0.48967212 -1.6366655 0.004219409 0.026396519 1.0 4339 tags=41%, list=29%, signal=57% BIOCARTA_DEATH_PATHWAY%MSIGDB_C2%BIOCARTA_DEATH_PATHWAY BIOCARTA_DEATH_PATHWAY%MSIGDB_C2%BIOCARTA_DEATH_PATHWAY 31 -0.5653503 -1.635814 0.0064935065 0.026574736 1.0 1236 tags=23%, list=8%, signal=25% TP53 REGULATES METABOLIC GENES%REACTOME DATABASE ID RELEASE 60%5628897 TP53 REGULATES METABOLIC GENES%REACTOME DATABASE ID RELEASE 60%5628897 66 -0.49725476 -1.6348276 0.0 0.026839025 1.0 2945 tags=35%, list=19%, signal=43% PURINE RIBONUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0046128 PURINE RIBONUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0046128 34 -0.5759628 -1.6340363 0.0036363637 0.027024817 1.0 4927 tags=50%, list=32%, signal=74% CELLULAR METABOLIC COMPOUND SALVAGE%GOBP%GO:0043094 CELLULAR METABOLIC COMPOUND SALVAGE%GOBP%GO:0043094 30 -0.5652172 -1.6339898 0.006116208 0.026990185 1.0 2338 tags=43%, list=15%, signal=51% PID_IL12_STAT4_PATHWAY%MSIGDB_C2%PID_IL12_STAT4_PATHWAY PID_IL12_STAT4_PATHWAY%MSIGDB_C2%PID_IL12_STAT4_PATHWAY 29 -0.5810272 -1.6323284 0.0147929 0.027417414 1.0 1714 tags=41%, list=11%, signal=47% FGFR2 ALTERNATIVE SPLICING%REACTOME%R-HSA-6803529.2 FGFR2 ALTERNATIVE SPLICING%REACTOME%R-HSA-6803529.2 25 -0.60812765 -1.6315715 0.0116959065 0.027606366 1.0 2682 tags=36%, list=18%, signal=44% MITOCHONDRIAL CALCIUM ION TRANSPORT%REACTOME DATABASE ID RELEASE 60%8949215 MITOCHONDRIAL CALCIUM ION TRANSPORT%REACTOME DATABASE ID RELEASE 60%8949215 16 -0.6833226 -1.631091 0.0 0.02774597 1.0 3835 tags=63%, list=25%, signal=83% TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0006368 TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0006368 85 -0.46167234 -1.6309533 0.0 0.027741682 1.0 2861 tags=29%, list=19%, signal=36% IL23-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL23-MEDIATED SIGNALING EVENTS IL23-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL23-MEDIATED SIGNALING EVENTS 25 -0.6074335 -1.6308678 0.012084592 0.027718075 1.0 3007 tags=52%, list=20%, signal=65% REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032944 REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032944 104 -0.45826435 -1.6296343 0.0 0.028039217 1.0 2257 tags=36%, list=15%, signal=41% POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903364 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903364 163 -0.4220861 -1.6295624 0.0 0.028008439 1.0 2265 tags=31%, list=15%, signal=36% TRIF-DEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0035666 TRIF-DEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0035666 28 -0.5986347 -1.629532 0.01857585 0.027970364 1.0 2753 tags=39%, list=18%, signal=48% RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER%REACTOME%R-HSA-76066.2 RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER%REACTOME%R-HSA-76066.2 27 -0.6016366 -1.6293283 0.008695652 0.027994402 1.0 3127 tags=41%, list=21%, signal=51% E2F MEDIATED REGULATION OF DNA REPLICATION%REACTOME%R-HSA-113510.3 E2F MEDIATED REGULATION OF DNA REPLICATION%REACTOME%R-HSA-113510.3 16 -0.6592307 -1.6291845 0.025069637 0.027987448 1.0 1966 tags=44%, list=13%, signal=50% ACTIVATION OF THE MRNA UPON BINDING OF THE CAP-BINDING COMPLEX AND EIFS, AND SUBSEQUENT BINDING TO 43S%REACTOME%R-HSA-72662.3 ACTIVATION OF THE MRNA UPON BINDING OF THE CAP-BINDING COMPLEX AND EIFS, AND SUBSEQUENT BINDING TO 43S%REACTOME%R-HSA-72662.3 58 -0.48771033 -1.6283469 0.0 0.028172763 1.0 6222 tags=67%, list=41%, signal=113% ERROR-FREE TRANSLESION SYNTHESIS%GOBP%GO:0070987 ERROR-FREE TRANSLESION SYNTHESIS%GOBP%GO:0070987 18 -0.6634045 -1.6269889 0.015075377 0.02852275 1.0 3290 tags=61%, list=22%, signal=78% TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 (RBL1) AND P130 (RBL2) IN COMPLEX WITH HDAC1%REACTOME DATABASE ID RELEASE 60%1362300 TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 (RBL1) AND P130 (RBL2) IN COMPLEX WITH HDAC1%REACTOME DATABASE ID RELEASE 60%1362300 16 -0.6888177 -1.6266934 0.012562814 0.02856015 1.0 4118 tags=75%, list=27%, signal=103% TRNA EXPORT FROM NUCLEUS%GOBP%GO:0006409 TRNA EXPORT FROM NUCLEUS%GOBP%GO:0006409 31 -0.5763227 -1.6266351 0.0064102565 0.028538242 1.0 4293 tags=58%, list=28%, signal=81% RIPK1-MEDIATED REGULATED NECROSIS%REACTOME DATABASE ID RELEASE 60%5213460 RIPK1-MEDIATED REGULATED NECROSIS%REACTOME DATABASE ID RELEASE 60%5213460 15 -0.6960526 -1.6265987 0.0070921984 0.028499732 1.0 1236 tags=33%, list=8%, signal=36% REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050670 REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050670 103 -0.45177683 -1.62629 0.0 0.028576378 1.0 2257 tags=35%, list=15%, signal=41% GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION%REACTOME%R-HSA-389661.5 GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION%REACTOME%R-HSA-389661.5 23 -0.6054635 -1.6245531 0.01690141 0.029028084 1.0 4758 tags=70%, list=31%, signal=101% RETINA HOMEOSTASIS%GOBP%GO:0001895 RETINA HOMEOSTASIS%GOBP%GO:0001895 33 -0.5736717 -1.6240629 0.0059701493 0.029105023 1.0 2693 tags=33%, list=18%, signal=40% MITOPHAGY%REACTOME%R-HSA-5205647.2 MITOPHAGY%REACTOME%R-HSA-5205647.2 26 -0.6021523 -1.6240444 0.0028901733 0.029061256 1.0 3106 tags=38%, list=20%, signal=48% BIOCARTA_NFKB_PATHWAY%MSIGDB_C2%BIOCARTA_NFKB_PATHWAY BIOCARTA_NFKB_PATHWAY%MSIGDB_C2%BIOCARTA_NFKB_PATHWAY 21 -0.63866985 -1.6237795 0.011299435 0.02908529 1.0 3245 tags=38%, list=21%, signal=48% DEADENYLATION-DEPENDENT MRNA DECAY%REACTOME%R-HSA-429914.2 DEADENYLATION-DEPENDENT MRNA DECAY%REACTOME%R-HSA-429914.2 54 -0.5051915 -1.6231076 0.0040650405 0.029223451 1.0 3338 tags=33%, list=22%, signal=43% POST-ELONGATION PROCESSING OF INTRONLESS PRE-MRNA%REACTOME DATABASE ID RELEASE 60%112297 POST-ELONGATION PROCESSING OF INTRONLESS PRE-MRNA%REACTOME DATABASE ID RELEASE 60%112297 28 -0.58964324 -1.6213319 0.011976048 0.029705629 1.0 2652 tags=39%, list=17%, signal=47% PROTEIN TRANSMEMBRANE TRANSPORT%GOBP%GO:0071806 PROTEIN TRANSMEMBRANE TRANSPORT%GOBP%GO:0071806 45 -0.5239592 -1.6206717 0.010909091 0.029854292 1.0 5275 tags=56%, list=35%, signal=85% REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051983 REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051983 71 -0.48472163 -1.6197658 0.004651163 0.030086208 1.0 1855 tags=30%, list=12%, signal=34% TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX%REACTOME%R-HSA-1362277.2 TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX%REACTOME%R-HSA-1362277.2 19 -0.6544434 -1.619739 0.01591512 0.030048251 1.0 4477 tags=74%, list=29%, signal=104% ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:0072655 ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:0072655 54 -0.49363425 -1.6196407 0.0038610038 0.03001987 1.0 3422 tags=43%, list=22%, signal=55% REGULATION OF ANTIGEN RECEPTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0050854 REGULATION OF ANTIGEN RECEPTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0050854 27 -0.5993481 -1.6185099 0.0065789474 0.030343585 1.0 2011 tags=41%, list=13%, signal=47% HEDGEHOG 'OFF' STATE%REACTOME DATABASE ID RELEASE 60%5610787 HEDGEHOG 'OFF' STATE%REACTOME DATABASE ID RELEASE 60%5610787 96 -0.4557068 -1.6183505 0.0 0.030358825 1.0 1616 tags=25%, list=11%, signal=28% TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:0010833 TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:0010833 21 -0.64274627 -1.6167566 0.010869565 0.030768875 1.0 3894 tags=52%, list=26%, signal=70% POSITIVE REGULATION OF T CELL MEDIATED IMMUNITY%GOBP%GO:0002711 POSITIVE REGULATION OF T CELL MEDIATED IMMUNITY%GOBP%GO:0002711 25 -0.5898346 -1.616488 0.014836796 0.030826835 1.0 2140 tags=36%, list=14%, signal=42% DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE%REACTOME%R-HSA-2559586.3 DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE%REACTOME%R-HSA-2559586.3 56 -0.5056322 -1.616065 0.0 0.03090753 1.0 3655 tags=46%, list=24%, signal=61% PINK PARKIN MEDIATED MITOPHAGY%REACTOME DATABASE ID RELEASE 60%5205685 PINK PARKIN MEDIATED MITOPHAGY%REACTOME DATABASE ID RELEASE 60%5205685 21 -0.6144733 -1.6154692 0.024456521 0.031056395 1.0 3106 tags=38%, list=20%, signal=48% DNA-TEMPLATED TRANSCRIPTION, TERMINATION%GOBP%GO:0006353 DNA-TEMPLATED TRANSCRIPTION, TERMINATION%GOBP%GO:0006353 91 -0.464606 -1.6140466 0.0 0.031502977 1.0 3885 tags=48%, list=26%, signal=65% PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:0070585 PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:0070585 58 -0.50068134 -1.6135273 0.0 0.031657834 1.0 3422 tags=41%, list=22%, signal=53% DNA STRAND ELONGATION%GOBP%GO:0022616 DNA STRAND ELONGATION%GOBP%GO:0022616 23 -0.62277585 -1.6122558 0.011267605 0.032013424 1.0 3939 tags=61%, list=26%, signal=82% MULTI-ORGANISM TRANSPORT%GOBP%GO:0044766 MULTI-ORGANISM TRANSPORT%GOBP%GO:0044766 151 -0.4245781 -1.6119013 0.0 0.03207387 1.0 3927 tags=40%, list=26%, signal=54% REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032649 REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032649 53 -0.5111965 -1.6102369 0.007633588 0.032564808 1.0 2140 tags=40%, list=14%, signal=46% MICRORNA (MIRNA) BIOGENESIS%REACTOME DATABASE ID RELEASE 60%203927 MICRORNA (MIRNA) BIOGENESIS%REACTOME DATABASE ID RELEASE 60%203927 18 -0.65354097 -1.6081614 0.0127551025 0.033114295 1.0 2940 tags=61%, list=19%, signal=76% NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION%GOBP%GO:1901988 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION%GOBP%GO:1901988 166 -0.41532227 -1.6077646 0.0 0.0332086 1.0 2247 tags=29%, list=15%, signal=34% T CELL MIGRATION%GOBP%GO:0072678 T CELL MIGRATION%GOBP%GO:0072678 16 -0.67000103 -1.6063015 0.019851116 0.033637006 1.0 1950 tags=44%, list=13%, signal=50% SUMOYLATION OF RNA BINDING PROTEINS%REACTOME DATABASE ID RELEASE 60%4570464 SUMOYLATION OF RNA BINDING PROTEINS%REACTOME DATABASE ID RELEASE 60%4570464 40 -0.53344226 -1.6058937 0.0033557047 0.033726387 1.0 4293 tags=48%, list=28%, signal=66% NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, NONSENSE-MEDIATED DECAY%GOBP%GO:0000184 NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, NONSENSE-MEDIATED DECAY%GOBP%GO:0000184 107 -0.44582346 -1.6058465 0.0 0.033681422 1.0 6240 tags=62%, list=41%, signal=104% REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS%GOBP%GO:0070228 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS%GOBP%GO:0070228 28 -0.5776956 -1.604468 0.02208202 0.034096356 1.0 1531 tags=50%, list=10%, signal=55% WNT SIGNALING PATHWAY, PLANAR CELL POLARITY PATHWAY%GOBP%GO:0060071 WNT SIGNALING PATHWAY, PLANAR CELL POLARITY PATHWAY%GOBP%GO:0060071 84 -0.46662083 -1.6033553 0.005263158 0.03436386 1.0 1584 tags=31%, list=10%, signal=34% METALLOPROTEASE DUBS%REACTOME%R-HSA-5689901.2 METALLOPROTEASE DUBS%REACTOME%R-HSA-5689901.2 25 -0.5941986 -1.6016032 0.016574586 0.03486458 1.0 4719 tags=56%, list=31%, signal=81% TRNA TRANSPORT%GOBP%GO:0051031 TRNA TRANSPORT%GOBP%GO:0051031 32 -0.5554547 -1.6015571 0.019417476 0.03483413 1.0 4293 tags=56%, list=28%, signal=78% PID_IL23_PATHWAY%MSIGDB_C2%PID_IL23_PATHWAY PID_IL23_PATHWAY%MSIGDB_C2%PID_IL23_PATHWAY 25 -0.6074335 -1.6003386 0.011142061 0.03518968 1.0 3007 tags=52%, list=20%, signal=65% TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST%REACTOME DATABASE ID RELEASE 60%6804114 TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST%REACTOME DATABASE ID RELEASE 60%6804114 18 -0.64289296 -1.5999407 0.023316063 0.035276733 1.0 4194 tags=67%, list=28%, signal=92% FORMATION OF THE TERNARY COMPLEX, AND SUBSEQUENTLY, THE 43S COMPLEX%REACTOME%R-HSA-72695.2 FORMATION OF THE TERNARY COMPLEX, AND SUBSEQUENTLY, THE 43S COMPLEX%REACTOME%R-HSA-72695.2 50 -0.50910336 -1.5998274 0.0 0.03527936 1.0 6222 tags=72%, list=41%, signal=121% PCP CE PATHWAY%REACTOME DATABASE ID RELEASE 60%4086400 PCP CE PATHWAY%REACTOME DATABASE ID RELEASE 60%4086400 88 -0.46069252 -1.5997397 0.006060606 0.035255108 1.0 1584 tags=30%, list=10%, signal=33% REGULATION OF SPINDLE ASSEMBLY%GOBP%GO:0090169 REGULATION OF SPINDLE ASSEMBLY%GOBP%GO:0090169 18 -0.63685435 -1.5991546 0.02917772 0.035388794 1.0 4268 tags=61%, list=28%, signal=85% PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM%GOBP%GO:0070972 PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM%GOBP%GO:0070972 117 -0.44399312 -1.5986365 0.0 0.035519898 1.0 6240 tags=61%, list=41%, signal=102% REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0040029 REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0040029 168 -0.41726446 -1.5979333 0.0 0.035739906 1.0 3326 tags=33%, list=22%, signal=42% BIOCARTA_FAS_PATHWAY%MSIGDB_C2%BIOCARTA_FAS_PATHWAY BIOCARTA_FAS_PATHWAY%MSIGDB_C2%BIOCARTA_FAS_PATHWAY 30 -0.57419515 -1.5951085 0.009202454 0.03671596 1.0 3152 tags=43%, list=21%, signal=55% NEGATIVE REGULATION OF MITOTIC CELL CYCLE PHASE TRANSITION%GOBP%GO:1901991 NEGATIVE REGULATION OF MITOTIC CELL CYCLE PHASE TRANSITION%GOBP%GO:1901991 162 -0.4238717 -1.5948234 0.0 0.036782637 1.0 2247 tags=30%, list=15%, signal=34% RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER%REACTOME%R-HSA-76061.2 RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER%REACTOME%R-HSA-76061.2 28 -0.578629 -1.5941834 0.009118541 0.036942482 1.0 3127 tags=39%, list=21%, signal=49% NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, EXONUCLEOLYTIC%GOBP%GO:0000291 NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, EXONUCLEOLYTIC%GOBP%GO:0000291 34 -0.54964095 -1.5940466 0.0033898305 0.036935974 1.0 3338 tags=41%, list=22%, signal=53% CELL REDOX HOMEOSTASIS%GOBP%GO:0045454 CELL REDOX HOMEOSTASIS%GOBP%GO:0045454 18 -0.64260155 -1.593929 0.01861702 0.036920633 1.0 3453 tags=61%, list=23%, signal=79% ABORTIVE ELONGATION OF HIV-1 TRANSCRIPT IN THE ABSENCE OF TAT%REACTOME%R-HSA-167242.2 ABORTIVE ELONGATION OF HIV-1 TRANSCRIPT IN THE ABSENCE OF TAT%REACTOME%R-HSA-167242.2 19 -0.62144154 -1.5934424 0.016216217 0.037026387 1.0 2682 tags=47%, list=18%, signal=57% EXECUTION PHASE OF APOPTOSIS%GOBP%GO:0097194 EXECUTION PHASE OF APOPTOSIS%GOBP%GO:0097194 50 -0.50573486 -1.5931982 0.00754717 0.037050437 1.0 3486 tags=38%, list=23%, signal=49% EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS%REACTOME%R-HSA-168274.2 EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS%REACTOME%R-HSA-168274.2 26 -0.5887976 -1.5901277 0.01179941 0.03818219 1.0 4293 tags=62%, list=28%, signal=86% FATTY ACID OXIDATION%GOBP%GO:0019395 FATTY ACID OXIDATION%GOBP%GO:0019395 54 -0.4867598 -1.5901165 0.0 0.038125545 1.0 3063 tags=41%, list=20%, signal=51% REGULATION OF NECROTIC CELL DEATH%GOBP%GO:0010939 REGULATION OF NECROTIC CELL DEATH%GOBP%GO:0010939 18 -0.6560133 -1.5899862 0.023376623 0.038115248 1.0 2247 tags=44%, list=15%, signal=52% MITOTIC NUCLEAR ENVELOPE DISASSEMBLY%GOBP%GO:0007077 MITOTIC NUCLEAR ENVELOPE DISASSEMBLY%GOBP%GO:0007077 40 -0.52992606 -1.5899298 0.010948905 0.03808082 1.0 953 tags=25%, list=6%, signal=27% MULTI-ORGANISM LOCALIZATION%GOBP%GO:1902579 MULTI-ORGANISM LOCALIZATION%GOBP%GO:1902579 151 -0.4245781 -1.5874791 0.0 0.038911927 1.0 3927 tags=40%, list=26%, signal=54% PYRIMIDINE NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0006213 PYRIMIDINE NUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0006213 23 -0.59537107 -1.5864886 0.011869436 0.039216246 1.0 1416 tags=43%, list=9%, signal=48% EPIGENETIC REGULATION OF GENE EXPRESSION%REACTOME%R-HSA-212165.1 EPIGENETIC REGULATION OF GENE EXPRESSION%REACTOME%R-HSA-212165.1 116 -0.42995548 -1.586349 0.0 0.039215185 1.0 3832 tags=38%, list=25%, signal=50% METAPHASE PLATE CONGRESSION%GOBP%GO:0051310 METAPHASE PLATE CONGRESSION%GOBP%GO:0051310 44 -0.5166345 -1.5849886 0.013513514 0.039662816 1.0 1915 tags=39%, list=13%, signal=44% AURORA A SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%AURORA A SIGNALING AURORA A SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%AURORA A SIGNALING 30 -0.5686927 -1.5848148 0.012345679 0.039669685 1.0 3079 tags=47%, list=20%, signal=58% IL2%NETPATH%IL2 IL2%NETPATH%IL2 79 -0.4595956 -1.5844557 0.004405286 0.03974764 1.0 2293 tags=28%, list=15%, signal=33% METALLO-SULFUR CLUSTER ASSEMBLY%GOBP%GO:0031163 METALLO-SULFUR CLUSTER ASSEMBLY%GOBP%GO:0031163 15 -0.65951675 -1.5826355 0.013020833 0.04036348 1.0 4121 tags=73%, list=27%, signal=100% MEMBRANE DISASSEMBLY%GOBP%GO:0030397 MEMBRANE DISASSEMBLY%GOBP%GO:0030397 42 -0.52384824 -1.5826312 0.011235955 0.040306676 1.0 953 tags=24%, list=6%, signal=25% GENE SILENCING%GOBP%GO:0016458 GENE SILENCING%GOBP%GO:0016458 94 -0.4541003 -1.5826133 0.005291005 0.04024989 1.0 3297 tags=33%, list=22%, signal=42% NUCLEAR IMPORT OF REV PROTEIN%REACTOME%R-HSA-180746.1 NUCLEAR IMPORT OF REV PROTEIN%REACTOME%R-HSA-180746.1 28 -0.5790032 -1.5820485 0.011204482 0.04041069 1.0 4293 tags=57%, list=28%, signal=79% NUCLEAR ENVELOPE DISASSEMBLY%GOBP%GO:0051081 NUCLEAR ENVELOPE DISASSEMBLY%GOBP%GO:0051081 42 -0.52384824 -1.5816896 0.014652015 0.040476464 1.0 953 tags=24%, list=6%, signal=25% TRANSLESION SYNTHESIS BY POLI%REACTOME%R-HSA-5656121.1 TRANSLESION SYNTHESIS BY POLI%REACTOME%R-HSA-5656121.1 17 -0.6430898 -1.5814015 0.030054646 0.040527232 1.0 4590 tags=71%, list=30%, signal=101% DNA METHYLATION%REACTOME DATABASE ID RELEASE 60%5334118 DNA METHYLATION%REACTOME DATABASE ID RELEASE 60%5334118 34 -0.5489596 -1.5811563 0.015673982 0.04054765 1.0 5479 tags=71%, list=36%, signal=110% POSITIVE REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903039 POSITIVE REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903039 146 -0.42244112 -1.5811172 0.0 0.040493175 1.0 2309 tags=38%, list=15%, signal=45% TRICARBOXYLIC ACID CYCLE%GOBP%GO:0006099 TRICARBOXYLIC ACID CYCLE%GOBP%GO:0006099 26 -0.58501214 -1.5809382 0.024390243 0.040496636 1.0 5409 tags=85%, list=36%, signal=131% NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY%REACTOME%R-HSA-168333.2 NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY%REACTOME%R-HSA-168333.2 26 -0.5887976 -1.5807816 0.01734104 0.04050711 1.0 4293 tags=62%, list=28%, signal=86% NUCLEAR ENVELOPE BREAKDOWN%REACTOME%R-HSA-2980766.1 NUCLEAR ENVELOPE BREAKDOWN%REACTOME%R-HSA-2980766.1 42 -0.52044755 -1.5801915 0.007142857 0.040648673 1.0 4293 tags=52%, list=28%, signal=73% NUCLEOTIDE SALVAGE%REACTOME%R-HSA-8956321.1 NUCLEOTIDE SALVAGE%REACTOME%R-HSA-8956321.1 20 -0.6233794 -1.5796195 0.020942409 0.04080103 1.0 1471 tags=45%, list=10%, signal=50% MATURATION OF 5.8S RRNA FROM TRICISTRONIC RRNA TRANSCRIPT (SSU-RRNA, 5.8S RRNA, LSU-RRNA)%GOBP%GO:0000466 MATURATION OF 5.8S RRNA FROM TRICISTRONIC RRNA TRANSCRIPT (SSU-RRNA, 5.8S RRNA, LSU-RRNA)%GOBP%GO:0000466 15 -0.65019476 -1.5781522 0.026699029 0.04132478 1.0 4958 tags=73%, list=33%, signal=109% REGULATION OF ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002822 REGULATION OF ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS%GOBP%GO:0002822 64 -0.48230356 -1.577535 0.007782101 0.041512243 1.0 2140 tags=31%, list=14%, signal=36% REGULATION OF CYTOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0001959 REGULATION OF CYTOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0001959 100 -0.4331984 -1.5767403 0.0053475937 0.041750696 1.0 2615 tags=34%, list=17%, signal=41% RECIPROCAL DNA RECOMBINATION%GOBP%GO:0035825 RECIPROCAL DNA RECOMBINATION%GOBP%GO:0035825 28 -0.57043856 -1.5765413 0.017857144 0.041767184 1.0 3438 tags=43%, list=23%, signal=55% ERROR-PRONE TRANSLESION SYNTHESIS%GOBP%GO:0042276 ERROR-PRONE TRANSLESION SYNTHESIS%GOBP%GO:0042276 20 -0.6230098 -1.5764306 0.015544041 0.041739274 1.0 4590 tags=65%, list=30%, signal=93% TRNA-CONTAINING RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071431 TRNA-CONTAINING RIBONUCLEOPROTEIN COMPLEX EXPORT FROM NUCLEUS%GOBP%GO:0071431 31 -0.5763227 -1.5763458 0.025889968 0.041717444 1.0 4293 tags=58%, list=28%, signal=81% TRANSLESION SYNTHESIS BY REV1%REACTOME%R-HSA-110312.1 TRANSLESION SYNTHESIS BY REV1%REACTOME%R-HSA-110312.1 16 -0.6498486 -1.575351 0.020565553 0.04205623 1.0 4590 tags=75%, list=30%, signal=107% CHROMOSOME CONDENSATION%GOBP%GO:0030261 CHROMOSOME CONDENSATION%GOBP%GO:0030261 18 -0.6367243 -1.5746908 0.013089005 0.042202204 1.0 4238 tags=61%, list=28%, signal=85% RECIPROCAL MEIOTIC RECOMBINATION%GOBP%GO:0007131 RECIPROCAL MEIOTIC RECOMBINATION%GOBP%GO:0007131 28 -0.57043856 -1.5742323 0.02601156 0.042321354 1.0 3438 tags=43%, list=23%, signal=55% PORPHYRIN-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0006778 PORPHYRIN-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0006778 22 -0.5885857 -1.5737731 0.018567638 0.042388044 1.0 2822 tags=45%, list=19%, signal=56% POSITIVE REGULATION OF LEUKOCYTE ACTIVATION%GOBP%GO:0002696 POSITIVE REGULATION OF LEUKOCYTE ACTIVATION%GOBP%GO:0002696 187 -0.4011632 -1.5733833 0.0 0.042459574 1.0 2309 tags=36%, list=15%, signal=42% HEME METABOLIC PROCESS%GOBP%GO:0042168 HEME METABOLIC PROCESS%GOBP%GO:0042168 20 -0.62093544 -1.5731821 0.02925532 0.04247877 1.0 2822 tags=50%, list=19%, signal=61% PID_AURORA_A_PATHWAY%MSIGDB_C2%PID_AURORA_A_PATHWAY PID_AURORA_A_PATHWAY%MSIGDB_C2%PID_AURORA_A_PATHWAY 30 -0.5686926 -1.5726956 0.022727273 0.04260943 1.0 3079 tags=47%, list=20%, signal=58% INTRACELLULAR PROTEIN TRANSMEMBRANE TRANSPORT%GOBP%GO:0065002 INTRACELLULAR PROTEIN TRANSMEMBRANE TRANSPORT%GOBP%GO:0065002 43 -0.5232427 -1.5722636 0.014492754 0.04272767 1.0 5275 tags=56%, list=35%, signal=85% BIOCARTA_NKCELLS_PATHWAY%MSIGDB_C2%BIOCARTA_NKCELLS_PATHWAY BIOCARTA_NKCELLS_PATHWAY%MSIGDB_C2%BIOCARTA_NKCELLS_PATHWAY 16 -0.65686435 -1.5712802 0.032911394 0.04299011 1.0 1014 tags=38%, list=7%, signal=40% BIOCARTA_TID_PATHWAY%MSIGDB_C2%BIOCARTA_TID_PATHWAY BIOCARTA_TID_PATHWAY%MSIGDB_C2%BIOCARTA_TID_PATHWAY 17 -0.64381003 -1.5711501 0.015625 0.042973574 1.0 1896 tags=35%, list=12%, signal=40% MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS%GOBP%GO:1902850 MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS%GOBP%GO:1902850 77 -0.45983884 -1.5710539 0.0 0.042956598 1.0 2825 tags=38%, list=19%, signal=46% CLEAVAGE INVOLVED IN RRNA PROCESSING%GOBP%GO:0000469 CLEAVAGE INVOLVED IN RRNA PROCESSING%GOBP%GO:0000469 18 -0.633587 -1.570714 0.028409092 0.043047573 1.0 4444 tags=61%, list=29%, signal=86% REGULATION OF DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0032784 REGULATION OF DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0032784 31 -0.5413116 -1.5695285 0.016891891 0.043507896 1.0 3885 tags=35%, list=26%, signal=48% POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070665 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070665 71 -0.460624 -1.5682037 0.0 0.044000093 1.0 2795 tags=41%, list=18%, signal=50% NOD1 2 SIGNALING PATHWAY%REACTOME%R-HSA-168638.1 NOD1 2 SIGNALING PATHWAY%REACTOME%R-HSA-168638.1 31 -0.56479675 -1.5677747 0.023728814 0.04408546 1.0 2310 tags=35%, list=15%, signal=42% RNA POLYMERASE I PROMOTER ESCAPE%REACTOME%R-HSA-73772.3 RNA POLYMERASE I PROMOTER ESCAPE%REACTOME%R-HSA-73772.3 30 -0.5483025 -1.5677004 0.028571429 0.04405287 1.0 3782 tags=43%, list=25%, signal=58% POSITIVE REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY%GOBP%GO:1904874 POSITIVE REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY%GOBP%GO:1904874 15 -0.6646069 -1.5673395 0.023076924 0.04411887 1.0 4475 tags=87%, list=29%, signal=123% TRANSCRIPTIONAL REGULATION BY RUNX3%REACTOME%R-HSA-8878159.1 TRANSCRIPTIONAL REGULATION BY RUNX3%REACTOME%R-HSA-8878159.1 107 -0.43533966 -1.566895 0.0 0.044209745 1.0 1867 tags=26%, list=12%, signal=30% 2'-DEOXYRIBONUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0009394 2'-DEOXYRIBONUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0009394 20 -0.6027429 -1.5661893 0.024193548 0.04442764 1.0 1691 tags=50%, list=11%, signal=56% FATTY ACID BETA-OXIDATION%GOBP%GO:0006635 FATTY ACID BETA-OXIDATION%GOBP%GO:0006635 44 -0.5103945 -1.5637782 0.0035842294 0.04528805 1.0 3063 tags=41%, list=20%, signal=51% CONVERSION FROM APC C:CDC20 TO APC C:CDH1 IN LATE ANAPHASE%REACTOME%R-HSA-176407.2 CONVERSION FROM APC C:CDC20 TO APC C:CDH1 IN LATE ANAPHASE%REACTOME%R-HSA-176407.2 18 -0.64490026 -1.5635746 0.024390243 0.045300856 1.0 2086 tags=33%, list=14%, signal=39% TRAIL%IOB%TRAIL TRAIL%IOB%TRAIL 55 -0.4876143 -1.5632272 0.0 0.045392327 1.0 3621 tags=44%, list=24%, signal=57% TAT-MEDIATED HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%167243 TAT-MEDIATED HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%167243 26 -0.57345474 -1.5629928 0.020289855 0.045400932 1.0 2788 tags=42%, list=18%, signal=52% PID_DNA_PK_PATHWAY%MSIGDB_C2%PID_DNA_PK_PATHWAY PID_DNA_PK_PATHWAY%MSIGDB_C2%PID_DNA_PK_PATHWAY 15 -0.66454566 -1.5609835 0.029411765 0.046131417 1.0 1225 tags=27%, list=8%, signal=29% ACTIVATION OF RRNA EXPRESSION BY ERCC6 (CSB) AND EHMT2 (G9A)%REACTOME DATABASE ID RELEASE 60%427389 ACTIVATION OF RRNA EXPRESSION BY ERCC6 (CSB) AND EHMT2 (G9A)%REACTOME DATABASE ID RELEASE 60%427389 47 -0.5038128 -1.560616 0.010752688 0.04621773 1.0 5568 tags=62%, list=37%, signal=97% HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%167287 HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%167287 28 -0.5668623 -1.5585715 0.017045455 0.047105774 1.0 2788 tags=39%, list=18%, signal=48% REGULATION OF RESPONSE TO CYTOKINE STIMULUS%GOBP%GO:0060759 REGULATION OF RESPONSE TO CYTOKINE STIMULUS%GOBP%GO:0060759 106 -0.43625668 -1.5581347 0.0 0.0472102 1.0 2615 tags=34%, list=17%, signal=41% TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS%REACTOME DATABASE ID RELEASE 60%168271 TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS%REACTOME DATABASE ID RELEASE 60%168271 26 -0.5598305 -1.557194 0.019553073 0.047499172 1.0 4293 tags=54%, list=28%, signal=75% POSITIVE REGULATION OF VIRAL PROCESS%GOBP%GO:0048524 POSITIVE REGULATION OF VIRAL PROCESS%GOBP%GO:0048524 86 -0.4476246 -1.557136 0.0 0.047454517 1.0 3780 tags=43%, list=25%, signal=57% TRANSLESION SYNTHESIS BY POLK%REACTOME DATABASE ID RELEASE 60%5655862 TRANSLESION SYNTHESIS BY POLK%REACTOME DATABASE ID RELEASE 60%5655862 17 -0.6403451 -1.5570693 0.027638191 0.047427904 1.0 4590 tags=71%, list=30%, signal=101% RIBONUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0009119 RIBONUCLEOSIDE METABOLIC PROCESS%GOBP%GO:0009119 45 -0.5195036 -1.5569712 0.010600707 0.047389477 1.0 4658 tags=49%, list=31%, signal=70% PAUSING AND RECOVERY OF HIV ELONGATION%REACTOME DATABASE ID RELEASE 60%167290 PAUSING AND RECOVERY OF HIV ELONGATION%REACTOME DATABASE ID RELEASE 60%167290 28 -0.5668623 -1.5567517 0.025 0.04741854 1.0 2788 tags=39%, list=18%, signal=48% POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002821 POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002821 44 -0.5178635 -1.5566875 0.02846975 0.047384255 1.0 2140 tags=32%, list=14%, signal=37% DNA REPLICATION-DEPENDENT NUCLEOSOME ASSEMBLY%GOBP%GO:0006335 DNA REPLICATION-DEPENDENT NUCLEOSOME ASSEMBLY%GOBP%GO:0006335 19 -0.6228455 -1.5559812 0.030379746 0.047649913 1.0 3655 tags=53%, list=24%, signal=69% EUKARYOTIC TRANSLATION ELONGATION%REACTOME DATABASE ID RELEASE 60%156842 EUKARYOTIC TRANSLATION ELONGATION%REACTOME DATABASE ID RELEASE 60%156842 89 -0.442822 -1.5550073 0.010989011 0.04802314 1.0 6240 tags=65%, list=41%, signal=110% POSITIVE REGULATION OF NF-KAPPAB TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0051092 POSITIVE REGULATION OF NF-KAPPAB TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0051092 107 -0.444632 -1.5547836 0.0 0.048052393 1.0 2570 tags=28%, list=17%, signal=34% EXONUCLEOLYTIC NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS INVOLVED IN DEADENYLATION-DEPENDENT DECAY%GOBP%GO:0043928 EXONUCLEOLYTIC NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS INVOLVED IN DEADENYLATION-DEPENDENT DECAY%GOBP%GO:0043928 32 -0.5445058 -1.5537448 0.0030959751 0.048452985 1.0 3338 tags=41%, list=22%, signal=52% NUCLEOTIDE-EXCISION REPAIR, DNA GAP FILLING%GOBP%GO:0006297 NUCLEOTIDE-EXCISION REPAIR, DNA GAP FILLING%GOBP%GO:0006297 24 -0.5890827 -1.5523865 0.021978023 0.0489605 1.0 3042 tags=46%, list=20%, signal=57% RIBOSOMAL SCANNING AND START CODON RECOGNITION%REACTOME%R-HSA-72702.3 RIBOSOMAL SCANNING AND START CODON RECOGNITION%REACTOME%R-HSA-72702.3 57 -0.48695114 -1.552174 0.0121951215 0.048989978 1.0 6222 tags=68%, list=41%, signal=115% PAUSING AND RECOVERY OF TAT-MEDIATED HIV ELONGATION%REACTOME DATABASE ID RELEASE 60%167238 PAUSING AND RECOVERY OF TAT-MEDIATED HIV ELONGATION%REACTOME DATABASE ID RELEASE 60%167238 26 -0.57345474 -1.5510256 0.011661808 0.049447853 1.0 2788 tags=42%, list=18%, signal=52% NEGATIVE REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002832 NEGATIVE REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002832 26 -0.5773173 -1.5502949 0.009584664 0.049705863 1.0 3463 tags=42%, list=23%, signal=55% TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA%REACTOME DATABASE ID RELEASE 60%159230 TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA%REACTOME DATABASE ID RELEASE 60%159230 29 -0.55120236 -1.54562 0.024539877 0.051670946 1.0 4293 tags=52%, list=28%, signal=72% DNA STRAND ELONGATION INVOLVED IN DNA REPLICATION%GOBP%GO:0006271 DNA STRAND ELONGATION INVOLVED IN DNA REPLICATION%GOBP%GO:0006271 18 -0.62503254 -1.5450414 0.020997375 0.051886644 1.0 3939 tags=67%, list=26%, signal=90% TRANSLATION INITIATION COMPLEX FORMATION%REACTOME DATABASE ID RELEASE 60%72649 TRANSLATION INITIATION COMPLEX FORMATION%REACTOME DATABASE ID RELEASE 60%72649 57 -0.4832954 -1.5449959 0.008097166 0.05184479 1.0 6222 tags=67%, list=41%, signal=112% POSITIVE REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032729 POSITIVE REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032729 35 -0.53476804 -1.5448879 0.024242423 0.051822748 1.0 3029 tags=46%, list=20%, signal=57% IRON-SULFUR CLUSTER ASSEMBLY%GOBP%GO:0016226 IRON-SULFUR CLUSTER ASSEMBLY%GOBP%GO:0016226 15 -0.65951675 -1.5448086 0.02955665 0.051779095 1.0 4121 tags=73%, list=27%, signal=100% POSITIVE REGULATION OF CELL ACTIVATION%GOBP%GO:0050867 POSITIVE REGULATION OF CELL ACTIVATION%GOBP%GO:0050867 193 -0.3930581 -1.5433863 0.0 0.052324396 1.0 2309 tags=35%, list=15%, signal=41% REGULATION OF T CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050856 REGULATION OF T CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050856 20 -0.60433203 -1.5429265 0.01977401 0.05245774 1.0 2011 tags=45%, list=13%, signal=52% DEOXYRIBONUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0009262 DEOXYRIBONUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0009262 24 -0.5897184 -1.5408916 0.017699115 0.053376142 1.0 3078 tags=63%, list=20%, signal=78% PIGMENT METABOLIC PROCESS%GOBP%GO:0042440 PIGMENT METABOLIC PROCESS%GOBP%GO:0042440 33 -0.5296246 -1.5406343 0.012232416 0.053419348 1.0 2822 tags=39%, list=19%, signal=48% DNA REPLICATION-DEPENDENT NUCLEOSOME ORGANIZATION%GOBP%GO:0034723 DNA REPLICATION-DEPENDENT NUCLEOSOME ORGANIZATION%GOBP%GO:0034723 19 -0.6228455 -1.5399659 0.032608695 0.053663645 1.0 3655 tags=53%, list=24%, signal=69% RESPONSE TO INTERFERON-ALPHA%GOBP%GO:0035455 RESPONSE TO INTERFERON-ALPHA%GOBP%GO:0035455 15 -0.63559043 -1.5397052 0.042183623 0.05371002 1.0 2609 tags=53%, list=17%, signal=64% NCRNA 3'-END PROCESSING%GOBP%GO:0043628 NCRNA 3'-END PROCESSING%GOBP%GO:0043628 18 -0.6339724 -1.5394883 0.020408163 0.053752527 1.0 4444 tags=67%, list=29%, signal=94% PRC2 METHYLATES HISTONES AND DNA%REACTOME%R-HSA-212300.1 PRC2 METHYLATES HISTONES AND DNA%REACTOME%R-HSA-212300.1 44 -0.5108181 -1.5389264 0.01980198 0.05395988 1.0 5479 tags=70%, list=36%, signal=110% REGULATION OF B CELL PROLIFERATION%GOBP%GO:0030888 REGULATION OF B CELL PROLIFERATION%GOBP%GO:0030888 29 -0.554334 -1.5388848 0.016722407 0.053911805 1.0 3843 tags=52%, list=25%, signal=69% MISMATCH REPAIR%GOBP%GO:0006298 MISMATCH REPAIR%GOBP%GO:0006298 26 -0.5620765 -1.5385817 0.010989011 0.054016136 1.0 1729 tags=35%, list=11%, signal=39% PROTEIN TRANSMEMBRANE IMPORT INTO INTRACELLULAR ORGANELLE%GOBP%GO:0044743 PROTEIN TRANSMEMBRANE IMPORT INTO INTRACELLULAR ORGANELLE%GOBP%GO:0044743 36 -0.52762127 -1.5380654 0.022875817 0.054167453 1.0 5275 tags=58%, list=35%, signal=89% SPINDLE ORGANIZATION%GOBP%GO:0007051 SPINDLE ORGANIZATION%GOBP%GO:0007051 97 -0.42458993 -1.5364268 0.0058479533 0.0548505 1.0 2825 tags=33%, list=19%, signal=40% DETOXIFICATION OF REACTIVE OXYGEN SPECIES%REACTOME%R-HSA-3299685.5 DETOXIFICATION OF REACTIVE OXYGEN SPECIES%REACTOME%R-HSA-3299685.5 30 -0.5517242 -1.5349094 0.025157232 0.055511497 1.0 2555 tags=53%, list=17%, signal=64% LIPID OXIDATION%GOBP%GO:0034440 LIPID OXIDATION%GOBP%GO:0034440 55 -0.48325175 -1.5336801 0.012345679 0.056021113 1.0 3063 tags=40%, list=20%, signal=50% REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE III PROMOTER%GOBP%GO:0006359 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE III PROMOTER%GOBP%GO:0006359 19 -0.6124394 -1.5336759 0.032786883 0.055947497 1.0 2626 tags=32%, list=17%, signal=38% NON-CANONICAL WNT SIGNALING PATHWAY%GOBP%GO:0035567 NON-CANONICAL WNT SIGNALING PATHWAY%GOBP%GO:0035567 108 -0.42248064 -1.5326226 0.0 0.056382176 1.0 1584 tags=25%, list=10%, signal=28% POSITIVE REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032946 POSITIVE REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032946 70 -0.4551166 -1.5321501 0.013824885 0.05654146 1.0 2795 tags=40%, list=18%, signal=49% POSITIVE REGULATION OF INTERLEUKIN-10 PRODUCTION%GOBP%GO:0032733 POSITIVE REGULATION OF INTERLEUKIN-10 PRODUCTION%GOBP%GO:0032733 18 -0.61186236 -1.5315764 0.030150754 0.05675782 1.0 2570 tags=56%, list=17%, signal=67% CHROMOSOME SEPARATION%GOBP%GO:0051304 CHROMOSOME SEPARATION%GOBP%GO:0051304 16 -0.633697 -1.5306777 0.032258064 0.057120208 1.0 3792 tags=56%, list=25%, signal=75% ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%112387 ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 60%112387 41 -0.5065251 -1.530121 0.030508475 0.057331264 1.0 2792 tags=34%, list=18%, signal=42% PROTEIN LOCALIZATION TO CHROMOSOME%GOBP%GO:0034502 PROTEIN LOCALIZATION TO CHROMOSOME%GOBP%GO:0034502 45 -0.4974931 -1.5300441 0.007194245 0.05729693 1.0 3550 tags=36%, list=23%, signal=46% SA_CASPASE_CASCADE%MSIGDB_C2%SA_CASPASE_CASCADE SA_CASPASE_CASCADE%MSIGDB_C2%SA_CASPASE_CASCADE 19 -0.6129654 -1.5291079 0.023188407 0.05767404 1.0 3152 tags=42%, list=21%, signal=53% JAK STAT SIGNALING PATHWAY%PANTHER PATHWAY%P00038 JAK STAT SIGNALING PATHWAY%PANTHER PATHWAY%P00038 15 -0.65059423 -1.5287855 0.032332562 0.057769556 1.0 2486 tags=40%, list=16%, signal=48% ANTIMICROBIAL PEPTIDES%REACTOME DATABASE ID RELEASE 60%6803157 ANTIMICROBIAL PEPTIDES%REACTOME DATABASE ID RELEASE 60%6803157 24 -0.5765242 -1.5283185 0.02247191 0.057918295 1.0 2309 tags=42%, list=15%, signal=49% SNRNA PROCESSING%GOBP%GO:0016180 SNRNA PROCESSING%GOBP%GO:0016180 18 -0.62330276 -1.5272692 0.02278481 0.058387216 1.0 1385 tags=28%, list=9%, signal=31% MEIOSIS%REACTOME%R-HSA-1500620.1 MEIOSIS%REACTOME%R-HSA-1500620.1 78 -0.44185343 -1.5269585 0.009478673 0.05844006 1.0 5369 tags=60%, list=35%, signal=93% T CELL MEDIATED IMMUNITY%GOBP%GO:0002456 T CELL MEDIATED IMMUNITY%GOBP%GO:0002456 16 -0.63607067 -1.5236335 0.039577838 0.059935395 1.0 3105 tags=44%, list=20%, signal=55% TCR SIGNALING IN NAIVE CD4+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TCR SIGNALING IN NAIVE CD4+ T CELLS TCR SIGNALING IN NAIVE CD4+ T CELLS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TCR SIGNALING IN NAIVE CD4+ T CELLS 64 -0.46216428 -1.5221752 0.008333334 0.060617447 1.0 2309 tags=34%, list=15%, signal=40% ST_TUMOR_NECROSIS_FACTOR_PATHWAY%MSIGDB_C2%ST_TUMOR_NECROSIS_FACTOR_PATHWAY ST_TUMOR_NECROSIS_FACTOR_PATHWAY%MSIGDB_C2%ST_TUMOR_NECROSIS_FACTOR_PATHWAY 28 -0.5510982 -1.522138 0.027777778 0.060552664 1.0 3346 tags=39%, list=22%, signal=50% MRNA CATABOLIC PROCESS%GOBP%GO:0006402 MRNA CATABOLIC PROCESS%GOBP%GO:0006402 188 -0.39624733 -1.5220127 0.0 0.06053027 1.0 5891 tags=54%, list=39%, signal=87% PID_TCR_PATHWAY%MSIGDB_C2%PID_TCR_PATHWAY PID_TCR_PATHWAY%MSIGDB_C2%PID_TCR_PATHWAY 65 -0.45781526 -1.5215085 0.00913242 0.060714956 1.0 2309 tags=34%, list=15%, signal=40% NUCLEOTIDE-BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING RECEPTOR (NLR) SIGNALING PATHWAYS%REACTOME%R-HSA-168643.1 NUCLEOTIDE-BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING RECEPTOR (NLR) SIGNALING PATHWAYS%REACTOME%R-HSA-168643.1 49 -0.4888941 -1.5214297 0.0038022813 0.060684707 1.0 2857 tags=33%, list=19%, signal=40% REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN%REACTOME%R-HSA-170822.2 REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN%REACTOME%R-HSA-170822.2 25 -0.56902903 -1.518129 0.027692307 0.062244967 1.0 4293 tags=56%, list=28%, signal=78% HATS ACETYLATE HISTONES%REACTOME%R-HSA-3214847.1 HATS ACETYLATE HISTONES%REACTOME%R-HSA-3214847.1 94 -0.4215481 -1.517554 0.0 0.06248194 1.0 5948 tags=59%, list=39%, signal=95% PROTEIN ADP-RIBOSYLATION%GOBP%GO:0006471 PROTEIN ADP-RIBOSYLATION%GOBP%GO:0006471 19 -0.6006133 -1.516177 0.048387095 0.06311961 1.0 3945 tags=53%, list=26%, signal=71% REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1901028 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1901028 42 -0.5040544 -1.5159749 0.029962547 0.063150935 1.0 2172 tags=26%, list=14%, signal=30% DEOXYRIBOSE PHOSPHATE METABOLIC PROCESS%GOBP%GO:0019692 DEOXYRIBOSE PHOSPHATE METABOLIC PROCESS%GOBP%GO:0019692 20 -0.6027429 -1.5155067 0.045698926 0.06329401 1.0 1691 tags=50%, list=11%, signal=56% BIOCARTA_IL2RB_PATHWAY%MSIGDB_C2%BIOCARTA_IL2RB_PATHWAY BIOCARTA_IL2RB_PATHWAY%MSIGDB_C2%BIOCARTA_IL2RB_PATHWAY 38 -0.5071507 -1.5150092 0.028391168 0.06350063 1.0 2240 tags=32%, list=15%, signal=37% MEIOSIS I%GOBP%GO:0007127 MEIOSIS I%GOBP%GO:0007127 43 -0.48480475 -1.5148158 0.013377926 0.06352326 1.0 4993 tags=58%, list=33%, signal=86% POSITIVE REGULATION OF CELL-CELL ADHESION%GOBP%GO:0022409 POSITIVE REGULATION OF CELL-CELL ADHESION%GOBP%GO:0022409 160 -0.3999449 -1.5119215 0.0 0.0650987 1.0 2309 tags=37%, list=15%, signal=43% REGULATION OF LYMPHOCYTE CHEMOTAXIS%GOBP%GO:1901623 REGULATION OF LYMPHOCYTE CHEMOTAXIS%GOBP%GO:1901623 16 -0.6211734 -1.5115651 0.054054055 0.06521826 1.0 1660 tags=38%, list=11%, signal=42% NONHOMOLOGOUS END-JOINING (NHEJ)%REACTOME DATABASE ID RELEASE 60%5693571 NONHOMOLOGOUS END-JOINING (NHEJ)%REACTOME DATABASE ID RELEASE 60%5693571 51 -0.47898373 -1.5114561 0.004201681 0.0652162 1.0 3736 tags=41%, list=25%, signal=54% NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS%GOBP%GO:0000956 NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS%GOBP%GO:0000956 182 -0.3935968 -1.5114057 0.0 0.0651522 1.0 5891 tags=54%, list=39%, signal=87% RNA POLYMERASE III TRANSCRIPTION%REACTOME DATABASE ID RELEASE 60%74158 RNA POLYMERASE III TRANSCRIPTION%REACTOME DATABASE ID RELEASE 60%74158 41 -0.502202 -1.5111635 0.0070921984 0.06521025 1.0 3812 tags=39%, list=25%, signal=52% NUCLEOTIDE-EXCISION REPAIR, DNA DAMAGE RECOGNITION%GOBP%GO:0000715 NUCLEOTIDE-EXCISION REPAIR, DNA DAMAGE RECOGNITION%GOBP%GO:0000715 23 -0.58623487 -1.5088551 0.04032258 0.06636655 1.0 4550 tags=57%, list=30%, signal=81% TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS%REACTOME DATABASE ID RELEASE 60%159234 TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS%REACTOME DATABASE ID RELEASE 60%159234 36 -0.5098836 -1.5070213 0.038732395 0.06723737 1.0 4293 tags=47%, list=28%, signal=66% CYTOSOLIC TRNA AMINOACYLATION%REACTOME%R-HSA-379716.1 CYTOSOLIC TRNA AMINOACYLATION%REACTOME%R-HSA-379716.1 24 -0.57170105 -1.5064771 0.036723163 0.06743413 1.0 4408 tags=50%, list=29%, signal=70% REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1900739 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1900739 29 -0.5409358 -1.5052899 0.024539877 0.06796965 1.0 2172 tags=31%, list=14%, signal=36% TOLL RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00054 TOLL RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00054 42 -0.4945126 -1.5046978 0.022875817 0.068204544 1.0 3544 tags=33%, list=23%, signal=43% CELLULAR DEFENSE RESPONSE%GOBP%GO:0006968 CELLULAR DEFENSE RESPONSE%GOBP%GO:0006968 40 -0.50329524 -1.5030642 0.021428572 0.068937264 1.0 3191 tags=43%, list=21%, signal=54% RMTS METHYLATE HISTONE ARGININES%REACTOME%R-HSA-3214858.2 RMTS METHYLATE HISTONE ARGININES%REACTOME%R-HSA-3214858.2 50 -0.47615263 -1.5015628 0.0 0.069677986 1.0 3746 tags=42%, list=25%, signal=56% TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6782315.4 TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6782315.4 35 -0.5099959 -1.5006123 0.027118644 0.0701309 1.0 5854 tags=63%, list=38%, signal=102% CITRIC ACID CYCLE (TCA CYCLE)%REACTOME%R-HSA-71403.1 CITRIC ACID CYCLE (TCA CYCLE)%REACTOME%R-HSA-71403.1 19 -0.5935768 -1.5005332 0.04450262 0.07009001 1.0 2952 tags=53%, list=19%, signal=65% TRANSCRIPTION ELONGATION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0006362 TRANSCRIPTION ELONGATION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0006362 29 -0.55676484 -1.5002712 0.020057306 0.07018267 1.0 3782 tags=45%, list=25%, signal=60% DNA GEOMETRIC CHANGE%GOBP%GO:0032392 DNA GEOMETRIC CHANGE%GOBP%GO:0032392 45 -0.48159432 -1.4997038 0.0073260074 0.07039682 1.0 4550 tags=49%, list=30%, signal=70% RNA POLYMERASE III ABORTIVE AND RETRACTIVE INITIATION%REACTOME%R-HSA-749476.2 RNA POLYMERASE III ABORTIVE AND RETRACTIVE INITIATION%REACTOME%R-HSA-749476.2 41 -0.502202 -1.4986643 0.012698413 0.070867784 1.0 3812 tags=39%, list=25%, signal=52% REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION%REACTOME DATABASE ID RELEASE 60%2565942 REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION%REACTOME DATABASE ID RELEASE 60%2565942 76 -0.43830255 -1.4968002 0.0045045046 0.071802124 1.0 3294 tags=32%, list=22%, signal=40% NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, DEADENYLATION-DEPENDENT DECAY%GOBP%GO:0000288 NUCLEAR-TRANSCRIBED MRNA CATABOLIC PROCESS, DEADENYLATION-DEPENDENT DECAY%GOBP%GO:0000288 58 -0.45558766 -1.4950653 0.011627907 0.07268056 1.0 3080 tags=31%, list=20%, signal=39% PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0006611 PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0006611 118 -0.4092908 -1.4945662 0.012578616 0.07290419 1.0 4293 tags=44%, list=28%, signal=61% SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS%GOBP%GO:0002200 SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS%GOBP%GO:0002200 22 -0.5727402 -1.4933674 0.04871795 0.073498785 1.0 2970 tags=32%, list=20%, signal=39% REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:1903747 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:1903747 109 -0.4084078 -1.491103 0.0 0.07473549 1.0 3288 tags=31%, list=22%, signal=40% DNA-DEPENDENT DNA REPLICATION MAINTENANCE OF FIDELITY%GOBP%GO:0045005 DNA-DEPENDENT DNA REPLICATION MAINTENANCE OF FIDELITY%GOBP%GO:0045005 27 -0.5332065 -1.4901159 0.03880597 0.075328395 1.0 5068 tags=59%, list=33%, signal=89% IFN-GAMMA%IOB%IFN-GAMMA IFN-GAMMA%IOB%IFN-GAMMA 41 -0.5093588 -1.4884946 0.04609929 0.07623613 1.0 2486 tags=24%, list=16%, signal=29% ST_T_CELL_SIGNAL_TRANSDUCTION%MSIGDB_C2%ST_T_CELL_SIGNAL_TRANSDUCTION ST_T_CELL_SIGNAL_TRANSDUCTION%MSIGDB_C2%ST_T_CELL_SIGNAL_TRANSDUCTION 43 -0.49288204 -1.4878263 0.034246575 0.07659454 1.0 3228 tags=42%, list=21%, signal=53% BIOCARTA_STRESS_PATHWAY%MSIGDB_C2%BIOCARTA_STRESS_PATHWAY BIOCARTA_STRESS_PATHWAY%MSIGDB_C2%BIOCARTA_STRESS_PATHWAY 24 -0.5658404 -1.4866602 0.054495912 0.077195354 1.0 3426 tags=38%, list=23%, signal=48% RNA PHOSPHODIESTER BOND HYDROLYSIS%GOBP%GO:0090501 RNA PHOSPHODIESTER BOND HYDROLYSIS%GOBP%GO:0090501 43 -0.49066195 -1.48652 0.044 0.07718188 1.0 4143 tags=51%, list=27%, signal=70% COENZYME METABOLIC PROCESS%GOBP%GO:0006732 COENZYME METABOLIC PROCESS%GOBP%GO:0006732 199 -0.38707814 -1.4864956 0.0 0.07709767 1.0 4586 tags=43%, list=30%, signal=61% POSITIVE REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050671 POSITIVE REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050671 69 -0.44633457 -1.4858257 0.004201681 0.07743916 1.0 2795 tags=39%, list=18%, signal=48% SOMATIC CELL DNA RECOMBINATION%GOBP%GO:0016444 SOMATIC CELL DNA RECOMBINATION%GOBP%GO:0016444 17 -0.5971792 -1.4850985 0.05655527 0.07772192 1.0 2970 tags=35%, list=20%, signal=44% GLUCONEOGENESIS%REACTOME%R-HSA-70263.1 GLUCONEOGENESIS%REACTOME%R-HSA-70263.1 26 -0.5463195 -1.4844902 0.029411765 0.07798517 1.0 3546 tags=38%, list=23%, signal=50% POSITIVE REGULATION OF PROTEIN OLIGOMERIZATION%GOBP%GO:0032461 POSITIVE REGULATION OF PROTEIN OLIGOMERIZATION%GOBP%GO:0032461 16 -0.6003876 -1.4839758 0.056790125 0.07818299 1.0 65 tags=13%, list=0%, signal=13% AURKA ACTIVATION BY TPX2%REACTOME%R-HSA-8854518.2 AURKA ACTIVATION BY TPX2%REACTOME%R-HSA-8854518.2 64 -0.44321585 -1.4828833 0.0042735045 0.078796424 1.0 3294 tags=33%, list=22%, signal=42% ESTABLISHMENT OF CHROMOSOME LOCALIZATION%GOBP%GO:0051303 ESTABLISHMENT OF CHROMOSOME LOCALIZATION%GOBP%GO:0051303 51 -0.47098437 -1.4822388 0.029850746 0.07909132 1.0 1915 tags=35%, list=13%, signal=40% PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002221 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002221 96 -0.41715208 -1.4816284 0.010471204 0.07933613 1.0 2327 tags=27%, list=15%, signal=32% BIOCARTA_TOLL_PATHWAY%MSIGDB_C2%BIOCARTA_TOLL_PATHWAY BIOCARTA_TOLL_PATHWAY%MSIGDB_C2%BIOCARTA_TOLL_PATHWAY 35 -0.5057428 -1.4812797 0.036544852 0.079455785 1.0 3332 tags=34%, list=22%, signal=44% INTERACTION WITH HOST%GOBP%GO:0051701 INTERACTION WITH HOST%GOBP%GO:0051701 196 -0.3797082 -1.4812751 0.0 0.07935913 1.0 4346 tags=40%, list=29%, signal=56% CHROMOSOME LOCALIZATION%GOBP%GO:0050000 CHROMOSOME LOCALIZATION%GOBP%GO:0050000 52 -0.4688701 -1.4803772 0.007874016 0.07985083 1.0 1915 tags=35%, list=13%, signal=39% HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY%MSIGDB_C2%HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY%MSIGDB_C2%HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY 45 -0.48453516 -1.4798677 0.031468533 0.08005798 1.0 5586 tags=69%, list=37%, signal=109% POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1901030 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1901030 36 -0.4995873 -1.4795824 0.03164557 0.08012929 1.0 2172 tags=28%, list=14%, signal=32% ESTABLISHMENT OF MITOTIC SPINDLE LOCALIZATION%GOBP%GO:0040001 ESTABLISHMENT OF MITOTIC SPINDLE LOCALIZATION%GOBP%GO:0040001 15 -0.6152142 -1.4784793 0.050724637 0.08072493 1.0 2256 tags=40%, list=15%, signal=47% NUCLEAR PORE COMPLEX (NPC) DISASSEMBLY%REACTOME DATABASE ID RELEASE 60%3301854 NUCLEAR PORE COMPLEX (NPC) DISASSEMBLY%REACTOME DATABASE ID RELEASE 60%3301854 30 -0.5322052 -1.4775558 0.037383176 0.08119051 1.0 4293 tags=57%, list=28%, signal=79% MITOCHONDRIAL TRNA AMINOACYLATION%REACTOME DATABASE ID RELEASE 60%379726 MITOCHONDRIAL TRNA AMINOACYLATION%REACTOME DATABASE ID RELEASE 60%379726 21 -0.5787604 -1.4759974 0.03206997 0.081995904 1.0 2852 tags=38%, list=19%, signal=47% CHEMOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0070098 CHEMOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0070098 37 -0.50023717 -1.4752458 0.025362318 0.08241008 1.0 1660 tags=30%, list=11%, signal=33% CILIUM MOVEMENT%GOBP%GO:0003341 CILIUM MOVEMENT%GOBP%GO:0003341 29 -0.523224 -1.4745603 0.05059524 0.082743876 1.0 5917 tags=62%, list=39%, signal=101% POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS%GOBP%GO:0060760 POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS%GOBP%GO:0060760 22 -0.5456022 -1.4737436 0.06051873 0.0832056 1.0 2327 tags=32%, list=15%, signal=38% CELL SEPARATION AFTER CYTOKINESIS%GOBP%GO:0000920 CELL SEPARATION AFTER CYTOKINESIS%GOBP%GO:0000920 16 -0.61918205 -1.4736192 0.05 0.08319991 1.0 4244 tags=56%, list=28%, signal=78% REGULATION OF MAST CELL ACTIVATION%GOBP%GO:0033003 REGULATION OF MAST CELL ACTIVATION%GOBP%GO:0033003 24 -0.54831177 -1.4734778 0.036827195 0.08320305 1.0 2327 tags=42%, list=15%, signal=49% CELL CYCLE CHECKPOINT%GOBP%GO:0000075 CELL CYCLE CHECKPOINT%GOBP%GO:0000075 166 -0.39172682 -1.4733447 0.0 0.08318637 1.0 3438 tags=35%, list=23%, signal=45% PHOSPHATIDYLCHOLINE METABOLIC PROCESS%GOBP%GO:0046470 PHOSPHATIDYLCHOLINE METABOLIC PROCESS%GOBP%GO:0046470 58 -0.44495103 -1.4725071 0.012552301 0.08361294 1.0 1768 tags=22%, list=12%, signal=25% I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0007249 I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0007249 56 -0.46170297 -1.4722607 0.029411765 0.083661534 1.0 3332 tags=34%, list=22%, signal=43% PYRIMIDINE-CONTAINING COMPOUND CATABOLIC PROCESS%GOBP%GO:0072529 PYRIMIDINE-CONTAINING COMPOUND CATABOLIC PROCESS%GOBP%GO:0072529 21 -0.57347786 -1.4720962 0.042613637 0.0836553 1.0 1691 tags=43%, list=11%, signal=48% PID_IL27_PATHWAY%MSIGDB_C2%PID_IL27_PATHWAY PID_IL27_PATHWAY%MSIGDB_C2%PID_IL27_PATHWAY 21 -0.5772144 -1.4717069 0.05221932 0.083780676 1.0 3029 tags=43%, list=20%, signal=53% REGULATION OF SPINDLE ORGANIZATION%GOBP%GO:0090224 REGULATION OF SPINDLE ORGANIZATION%GOBP%GO:0090224 29 -0.52297956 -1.470586 0.045454547 0.084398694 1.0 4293 tags=59%, list=28%, signal=82% HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA 19 -0.58525604 -1.4699757 0.043814432 0.08473805 1.0 3341 tags=37%, list=22%, signal=47% C-MYC PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%C-MYC PATHWAY C-MYC PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%C-MYC PATHWAY 25 -0.5441449 -1.4697723 0.04775281 0.08479518 1.0 4701 tags=60%, list=31%, signal=87% NEGATIVE REGULATION OF LIPID STORAGE%GOBP%GO:0010888 NEGATIVE REGULATION OF LIPID STORAGE%GOBP%GO:0010888 15 -0.61409193 -1.4679025 0.053658538 0.085844316 1.0 392 tags=20%, list=3%, signal=21% NEF-MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS%REACTOME DATABASE ID RELEASE 60%164938 NEF-MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS%REACTOME DATABASE ID RELEASE 60%164938 21 -0.56683594 -1.4678676 0.04519774 0.085768625 1.0 2510 tags=29%, list=17%, signal=34% NUCLEOSIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009163 NUCLEOSIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009163 26 -0.54890275 -1.4662194 0.056657225 0.08679653 1.0 1384 tags=31%, list=9%, signal=34% T CELL ACTIVATION%GOBP%GO:0042110 T CELL ACTIVATION%GOBP%GO:0042110 105 -0.41129506 -1.4655036 0.0056179776 0.08711155 1.0 2309 tags=34%, list=15%, signal=40% REGULATION OF INTERLEUKIN-4 PRODUCTION%GOBP%GO:0032673 REGULATION OF INTERLEUKIN-4 PRODUCTION%GOBP%GO:0032673 17 -0.60119855 -1.4634447 0.066313 0.08836447 1.0 2135 tags=41%, list=14%, signal=48% MATURATION OF LSU-RRNA%GOBP%GO:0000470 MATURATION OF LSU-RRNA%GOBP%GO:0000470 21 -0.5565649 -1.4633607 0.05263158 0.08831946 1.0 4217 tags=48%, list=28%, signal=66% PARKINSON DISEASE%PANTHER PATHWAY%P00049 PARKINSON DISEASE%PANTHER PATHWAY%P00049 78 -0.4302728 -1.4628994 0.004651163 0.08850314 1.0 1507 tags=22%, list=10%, signal=24% REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY%GOBP%GO:1904872 REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY%GOBP%GO:1904872 18 -0.5986023 -1.4627539 0.058252428 0.08847345 1.0 4475 tags=78%, list=29%, signal=110% 'DE NOVO' PROTEIN FOLDING%GOBP%GO:0006458 'DE NOVO' PROTEIN FOLDING%GOBP%GO:0006458 27 -0.5300822 -1.4620507 0.032786883 0.088818066 1.0 5618 tags=70%, list=37%, signal=111% POSITIVE REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002833 POSITIVE REGULATION OF RESPONSE TO BIOTIC STIMULUS%GOBP%GO:0002833 22 -0.5758224 -1.4605821 0.057894737 0.089748174 1.0 2055 tags=36%, list=14%, signal=42% SUPERPATHWAY OF CHOLESTEROL BIOSYNTHESIS%HUMANCYC%PWY66-5 SUPERPATHWAY OF CHOLESTEROL BIOSYNTHESIS%HUMANCYC%PWY66-5 25 -0.5447322 -1.4590995 0.042134833 0.09056865 1.0 2331 tags=32%, list=15%, signal=38% PID_NFKAPPAB_ATYPICAL_PATHWAY%MSIGDB_C2%PID_NFKAPPAB_ATYPICAL_PATHWAY PID_NFKAPPAB_ATYPICAL_PATHWAY%MSIGDB_C2%PID_NFKAPPAB_ATYPICAL_PATHWAY 16 -0.6000397 -1.4584483 0.065104164 0.09092263 1.0 3007 tags=56%, list=20%, signal=70% RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE%REACTOME DATABASE ID RELEASE 60%77075 RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE%REACTOME DATABASE ID RELEASE 60%77075 27 -0.52215314 -1.4583039 0.04494382 0.09091424 1.0 2682 tags=37%, list=18%, signal=45% NUCLEOTIDE METABOLISM%REACTOME DATABASE ID RELEASE 60%15869 NUCLEOTIDE METABOLISM%REACTOME DATABASE ID RELEASE 60%15869 81 -0.42905372 -1.4579558 0.023923445 0.09106218 1.0 4055 tags=53%, list=27%, signal=72% MMR%REACTOME DATABASE ID RELEASE 60%5358508 MMR%REACTOME DATABASE ID RELEASE 60%5358508 15 -0.6369741 -1.4573991 0.04639175 0.0913513 1.0 2567 tags=40%, list=17%, signal=48% HIV TRANSCRIPTION ELONGATION%REACTOME%R-HSA-167169.2 HIV TRANSCRIPTION ELONGATION%REACTOME%R-HSA-167169.2 38 -0.48641852 -1.4572129 0.025396826 0.09135346 1.0 3782 tags=42%, list=25%, signal=56% GLYCOSYL COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:1901659 GLYCOSYL COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:1901659 27 -0.54714423 -1.4566307 0.049853373 0.091612116 1.0 1384 tags=30%, list=9%, signal=33% INTERLEUKIN-10 SIGNALING%REACTOME DATABASE ID RELEASE 60%6783783 INTERLEUKIN-10 SIGNALING%REACTOME DATABASE ID RELEASE 60%6783783 39 -0.49496764 -1.4566147 0.043624163 0.09151591 1.0 1660 tags=23%, list=11%, signal=26% MTORC1-MEDIATED SIGNALLING%REACTOME%R-HSA-166208.2 MTORC1-MEDIATED SIGNALLING%REACTOME%R-HSA-166208.2 18 -0.5802168 -1.4562947 0.074074075 0.09163954 1.0 2945 tags=33%, list=19%, signal=41% B CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050853 B CELL RECEPTOR SIGNALING PATHWAY%GOBP%GO:0050853 24 -0.5401845 -1.4558964 0.04601227 0.09180393 1.0 3843 tags=63%, list=25%, signal=83% RNA POLYMERASE I TRANSCRIPTION INITIATION%REACTOME%R-HSA-73762.3 RNA POLYMERASE I TRANSCRIPTION INITIATION%REACTOME%R-HSA-73762.3 47 -0.46601555 -1.4551718 0.019762846 0.0922154 1.0 4044 tags=36%, list=27%, signal=49% POSITIVE REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034123 POSITIVE REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034123 16 -0.58675605 -1.4547337 0.07692308 0.09239878 1.0 995 tags=31%, list=7%, signal=33% TRANSPORT OF THE SLBP INDEPENDENT MATURE MRNA%REACTOME DATABASE ID RELEASE 60%159227 TRANSPORT OF THE SLBP INDEPENDENT MATURE MRNA%REACTOME DATABASE ID RELEASE 60%159227 28 -0.5324712 -1.4533051 0.053521127 0.093271434 1.0 4293 tags=50%, list=28%, signal=70% HISTONE MRNA METABOLIC PROCESS%GOBP%GO:0008334 HISTONE MRNA METABOLIC PROCESS%GOBP%GO:0008334 28 -0.52604574 -1.4524097 0.021806853 0.0937899 1.0 1445 tags=25%, list=9%, signal=28% SPINDLE ASSEMBLY%GOBP%GO:0051225 SPINDLE ASSEMBLY%GOBP%GO:0051225 59 -0.4516795 -1.4517697 0.008 0.094084874 1.0 2741 tags=32%, list=18%, signal=39% RNA METHYLATION%GOBP%GO:0001510 RNA METHYLATION%GOBP%GO:0001510 30 -0.528661 -1.4513835 0.036827195 0.09425242 1.0 3258 tags=37%, list=21%, signal=47% FORMATION OF THE EARLY ELONGATION COMPLEX%REACTOME DATABASE ID RELEASE 60%113418 FORMATION OF THE EARLY ELONGATION COMPLEX%REACTOME DATABASE ID RELEASE 60%113418 29 -0.5195433 -1.4508615 0.045845274 0.09451172 1.0 2682 tags=38%, list=18%, signal=46% DNA DAMAGE RESPONSE, DETECTION OF DNA DAMAGE%GOBP%GO:0042769 DNA DAMAGE RESPONSE, DETECTION OF DNA DAMAGE%GOBP%GO:0042769 33 -0.508817 -1.4503696 0.04573171 0.09475423 1.0 3042 tags=48%, list=20%, signal=60% TRAF6 MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-933542.1 TRAF6 MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-933542.1 25 -0.55137926 -1.450257 0.0625 0.094716765 1.0 3875 tags=48%, list=25%, signal=64% INTERCONVERSION OF NUCLEOTIDE DI- AND TRIPHOSPHATES%REACTOME%R-HSA-499943.5 INTERCONVERSION OF NUCLEOTIDE DI- AND TRIPHOSPHATES%REACTOME%R-HSA-499943.5 25 -0.5300266 -1.4495938 0.049535602 0.095046304 1.0 3640 tags=64%, list=24%, signal=84% REGULATION OF MITOTIC SISTER CHROMATID SEPARATION%GOBP%GO:0010965 REGULATION OF MITOTIC SISTER CHROMATID SEPARATION%GOBP%GO:0010965 38 -0.4785323 -1.4490833 0.044728436 0.09528383 1.0 1817 tags=34%, list=12%, signal=39% SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS VIA GERMLINE RECOMBINATION WITHIN A SINGLE LOCUS%GOBP%GO:0002562 SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS VIA GERMLINE RECOMBINATION WITHIN A SINGLE LOCUS%GOBP%GO:0002562 17 -0.5971792 -1.4489366 0.04557641 0.09527312 1.0 2970 tags=35%, list=20%, signal=44% SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE (SASP)%REACTOME%R-HSA-2559582.2 SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE (SASP)%REACTOME%R-HSA-2559582.2 78 -0.42077518 -1.447841 0.014285714 0.095915325 1.0 3655 tags=41%, list=24%, signal=54% TAT-MEDIATED ELONGATION OF THE HIV-1 TRANSCRIPT%REACTOME%R-HSA-167246.2 TAT-MEDIATED ELONGATION OF THE HIV-1 TRANSCRIPT%REACTOME%R-HSA-167246.2 38 -0.48641852 -1.4469565 0.042307694 0.096381575 1.0 3782 tags=42%, list=25%, signal=56% LYMPHOCYTE ACTIVATION%GOBP%GO:0046649 LYMPHOCYTE ACTIVATION%GOBP%GO:0046649 167 -0.38139498 -1.4464369 0.0 0.09663272 1.0 2195 tags=29%, list=14%, signal=33% REGULATION OF LEUKOCYTE APOPTOTIC PROCESS%GOBP%GO:2000106 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS%GOBP%GO:2000106 46 -0.48614237 -1.4460332 0.025925925 0.09680836 1.0 1531 tags=37%, list=10%, signal=41% POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1900740 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1900740 29 -0.5409358 -1.4455271 0.048543688 0.09700885 1.0 2172 tags=31%, list=14%, signal=36% LYSOSOME VESICLE BIOGENESIS%REACTOME%R-HSA-432720.1 LYSOSOME VESICLE BIOGENESIS%REACTOME%R-HSA-432720.1 34 -0.4928223 -1.444924 0.025641026 0.09734424 1.0 2974 tags=29%, list=20%, signal=36% IL27-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL27-MEDIATED SIGNALING EVENTS IL27-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL27-MEDIATED SIGNALING EVENTS 21 -0.5772144 -1.4441314 0.059945505 0.09781784 1.0 3029 tags=43%, list=20%, signal=53% FORMATION OF INCISION COMPLEX IN GG-NER%REACTOME%R-HSA-5696395.1 FORMATION OF INCISION COMPLEX IN GG-NER%REACTOME%R-HSA-5696395.1 43 -0.4727322 -1.4434745 0.04290429 0.098196305 1.0 4550 tags=49%, list=30%, signal=69% BIOCARTA_CSK_PATHWAY%MSIGDB_C2%BIOCARTA_CSK_PATHWAY BIOCARTA_CSK_PATHWAY%MSIGDB_C2%BIOCARTA_CSK_PATHWAY 20 -0.5842687 -1.4433154 0.04034582 0.098202474 1.0 2309 tags=45%, list=15%, signal=53% PID_HIF1A_PATHWAY%MSIGDB_C2%PID_HIF1A_PATHWAY PID_HIF1A_PATHWAY%MSIGDB_C2%PID_HIF1A_PATHWAY 19 -0.58525604 -1.4428904 0.05464481 0.098379634 1.0 3341 tags=37%, list=22%, signal=47% RESOLUTION OF D-LOOP STRUCTURES%REACTOME%R-HSA-5693537.1 RESOLUTION OF D-LOOP STRUCTURES%REACTOME%R-HSA-5693537.1 27 -0.50925595 -1.4423795 0.04761905 0.09863674 1.0 5059 tags=63%, list=33%, signal=94% TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX%REACTOME%R-HSA-445989.2 TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX%REACTOME%R-HSA-445989.2 29 -0.5212777 -1.4422241 0.05015674 0.09863044 1.0 3875 tags=48%, list=25%, signal=65% PEPTIDYL-LYSINE MODIFICATION%GOBP%GO:0018205 PEPTIDYL-LYSINE MODIFICATION%GOBP%GO:0018205 186 -0.37551966 -1.441692 0.0 0.09891306 1.0 4406 tags=35%, list=29%, signal=49% TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT%REACTOME DATABASE ID RELEASE 60%159231 TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT%REACTOME DATABASE ID RELEASE 60%159231 35 -0.49282703 -1.441636 0.036789298 0.09884819 1.0 5406 tags=60%, list=36%, signal=93% MACROAUTOPHAGY%REACTOME%R-HSA-1632852.3 MACROAUTOPHAGY%REACTOME%R-HSA-1632852.3 55 -0.4486356 -1.4411614 0.03875969 0.09906755 1.0 4317 tags=36%, list=28%, signal=51% NUCLEAR EXPORT%GOBP%GO:0051168 NUCLEAR EXPORT%GOBP%GO:0051168 126 -0.39196885 -1.4406543 0.0057471264 0.09936017 1.0 4293 tags=43%, list=28%, signal=59% CENTROSOME MATURATION%REACTOME DATABASE ID RELEASE 60%380287 CENTROSOME MATURATION%REACTOME DATABASE ID RELEASE 60%380287 70 -0.42743313 -1.4399977 0.018181818 0.099686354 1.0 1827 tags=20%, list=12%, signal=23% REGULATION OF T CELL DIFFERENTIATION%GOBP%GO:0045580 REGULATION OF T CELL DIFFERENTIATION%GOBP%GO:0045580 58 -0.44226912 -1.4398942 0.02661597 0.09963114 1.0 2140 tags=41%, list=14%, signal=48% REGULATION OF NECROPTOTIC PROCESS%GOBP%GO:0060544 REGULATION OF NECROPTOTIC PROCESS%GOBP%GO:0060544 15 -0.6187837 -1.4398675 0.065656565 0.09955115 1.0 4440 tags=67%, list=29%, signal=94% LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001909 LEUKOCYTE MEDIATED CYTOTOXICITY%GOBP%GO:0001909 16 -0.59937257 -1.4391363 0.056234717 0.09995076 1.0 897 tags=25%, list=6%, signal=27% TETRAPYRROLE BIOSYNTHETIC PROCESS%GOBP%GO:0033014 TETRAPYRROLE BIOSYNTHETIC PROCESS%GOBP%GO:0033014 18 -0.57887465 -1.4377202 0.06361323 0.10086945 1.0 2822 tags=50%, list=19%, signal=61% RIP-MEDIATED NFKB ACTIVATION VIA ZBP1%REACTOME%R-HSA-1810476.1 RIP-MEDIATED NFKB ACTIVATION VIA ZBP1%REACTOME%R-HSA-1810476.1 22 -0.5538394 -1.437241 0.0787172 0.10111584 1.0 3875 tags=55%, list=25%, signal=73% MITOTIC SPINDLE ORGANIZATION%GOBP%GO:0007052 MITOTIC SPINDLE ORGANIZATION%GOBP%GO:0007052 65 -0.44504678 -1.436265 0.023696683 0.101695776 1.0 2825 tags=37%, list=19%, signal=45% REGULATION OF DOUBLE-STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION%GOBP%GO:0010569 REGULATION OF DOUBLE-STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION%GOBP%GO:0010569 19 -0.57970256 -1.4359465 0.06982543 0.10182718 1.0 2772 tags=47%, list=18%, signal=58% RNA POLYMERASE II TRANSCRIPTION ELONGATION%REACTOME DATABASE ID RELEASE 60%75955 RNA POLYMERASE II TRANSCRIPTION ELONGATION%REACTOME DATABASE ID RELEASE 60%75955 53 -0.44551408 -1.4353231 0.02661597 0.10220584 1.0 2792 tags=30%, list=18%, signal=37% IKK COMPLEX RECRUITMENT MEDIATED BY RIP1%REACTOME DATABASE ID RELEASE 60%937041 IKK COMPLEX RECRUITMENT MEDIATED BY RIP1%REACTOME DATABASE ID RELEASE 60%937041 23 -0.56176597 -1.4350836 0.06481481 0.10224949 1.0 2310 tags=35%, list=15%, signal=41% ZBP1(DAI) MEDIATED INDUCTION OF TYPE I IFNS%REACTOME DATABASE ID RELEASE 60%1606322 ZBP1(DAI) MEDIATED INDUCTION OF TYPE I IFNS%REACTOME DATABASE ID RELEASE 60%1606322 25 -0.53623617 -1.434299 0.051829267 0.10268223 1.0 3875 tags=52%, list=25%, signal=70% PID_IL2_PI3K_PATHWAY%MSIGDB_C2%PID_IL2_PI3K_PATHWAY PID_IL2_PI3K_PATHWAY%MSIGDB_C2%PID_IL2_PI3K_PATHWAY 33 -0.50140584 -1.4342235 0.029761905 0.10263379 1.0 3007 tags=33%, list=20%, signal=41% REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0046782 REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0046782 55 -0.45535028 -1.4334078 0.04296875 0.10316791 1.0 3095 tags=38%, list=20%, signal=48% RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES%REACTOME%R-HSA-380270.1 RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES%REACTOME%R-HSA-380270.1 70 -0.42743313 -1.4333997 0.034313727 0.103058524 1.0 1827 tags=20%, list=12%, signal=23% CELLULAR RESPONSE TO GLUCOSE STARVATION%GOBP%GO:0042149 CELLULAR RESPONSE TO GLUCOSE STARVATION%GOBP%GO:0042149 31 -0.51595205 -1.4322377 0.047468353 0.10377948 1.0 3762 tags=35%, list=25%, signal=47% FORMATION OF HIV-1 ELONGATION COMPLEX CONTAINING HIV-1 TAT%REACTOME DATABASE ID RELEASE 60%167200 FORMATION OF HIV-1 ELONGATION COMPLEX CONTAINING HIV-1 TAT%REACTOME DATABASE ID RELEASE 60%167200 38 -0.48641852 -1.4313134 0.044827588 0.104302175 1.0 3782 tags=42%, list=25%, signal=56% FORMATION OF THE HIV-1 EARLY ELONGATION COMPLEX%REACTOME%R-HSA-167158.2 FORMATION OF THE HIV-1 EARLY ELONGATION COMPLEX%REACTOME%R-HSA-167158.2 29 -0.5195433 -1.4309618 0.06779661 0.104430355 1.0 2682 tags=38%, list=18%, signal=46% DEFENSE RESPONSE TO BACTERIUM%GOBP%GO:0042742 DEFENSE RESPONSE TO BACTERIUM%GOBP%GO:0042742 68 -0.42949474 -1.4306526 0.014018691 0.104553066 1.0 2570 tags=34%, list=17%, signal=41% POSITIVE REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0045948 POSITIVE REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0045948 19 -0.57891047 -1.4306345 0.062337663 0.1044526 1.0 2203 tags=32%, list=14%, signal=37% REGULATION OF VIRAL ENTRY INTO HOST CELL%GOBP%GO:0046596 REGULATION OF VIRAL ENTRY INTO HOST CELL%GOBP%GO:0046596 22 -0.54516345 -1.4288023 0.050147492 0.105699286 1.0 932 tags=23%, list=6%, signal=24% RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE DURING HIV INFECTION%REACTOME DATABASE ID RELEASE 60%167160 RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE DURING HIV INFECTION%REACTOME DATABASE ID RELEASE 60%167160 27 -0.52215314 -1.428497 0.048850574 0.105796374 1.0 2682 tags=37%, list=18%, signal=45% CELL CYCLE G1/S PHASE TRANSITION%GOBP%GO:0044843 CELL CYCLE G1/S PHASE TRANSITION%GOBP%GO:0044843 94 -0.40263432 -1.42652 0.021276595 0.10706116 1.0 2567 tags=41%, list=17%, signal=50% NCRNA CATABOLIC PROCESS%GOBP%GO:0034661 NCRNA CATABOLIC PROCESS%GOBP%GO:0034661 19 -0.5714878 -1.4265097 0.067708336 0.10695507 1.0 4852 tags=63%, list=32%, signal=93% FORMATION OF HIV ELONGATION COMPLEX IN THE ABSENCE OF HIV TAT%REACTOME DATABASE ID RELEASE 60%167152 FORMATION OF HIV ELONGATION COMPLEX IN THE ABSENCE OF HIV TAT%REACTOME DATABASE ID RELEASE 60%167152 40 -0.48169973 -1.4248041 0.03691275 0.108070426 1.0 3782 tags=40%, list=25%, signal=53% REGULATION OF MRNA SPLICING, VIA SPLICEOSOME%GOBP%GO:0048024 REGULATION OF MRNA SPLICING, VIA SPLICEOSOME%GOBP%GO:0048024 34 -0.49360108 -1.4246829 0.05263158 0.10804283 1.0 3711 tags=35%, list=24%, signal=47% MEIOTIC CHROMOSOME SEGREGATION%GOBP%GO:0045132 MEIOTIC CHROMOSOME SEGREGATION%GOBP%GO:0045132 27 -0.5220369 -1.4241877 0.051136363 0.10831252 1.0 3438 tags=48%, list=23%, signal=62% QUINONE METABOLIC PROCESS%GOBP%GO:1901661 QUINONE METABOLIC PROCESS%GOBP%GO:1901661 22 -0.54706717 -1.4223884 0.064599484 0.10953558 1.0 3037 tags=32%, list=20%, signal=40% REGULATION OF ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046634 REGULATION OF ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046634 44 -0.4639249 -1.420598 0.049242426 0.11070525 1.0 2167 tags=41%, list=14%, signal=48% HALLMARK_MTORC1_SIGNALING%MSIGDB_C2%HALLMARK_MTORC1_SIGNALING HALLMARK_MTORC1_SIGNALING%MSIGDB_C2%HALLMARK_MTORC1_SIGNALING 198 -0.3664533 -1.4201727 0.0 0.11092278 1.0 4088 tags=44%, list=27%, signal=59% PEROXISOME ORGANIZATION%GOBP%GO:0007031 PEROXISOME ORGANIZATION%GOBP%GO:0007031 28 -0.5250158 -1.4198639 0.0625 0.11105215 1.0 4374 tags=46%, list=29%, signal=65% PID_NFKAPPAB_CANONICAL_PATHWAY%MSIGDB_C2%PID_NFKAPPAB_CANONICAL_PATHWAY PID_NFKAPPAB_CANONICAL_PATHWAY%MSIGDB_C2%PID_NFKAPPAB_CANONICAL_PATHWAY 22 -0.5354038 -1.4198011 0.057692308 0.11096673 1.0 3392 tags=50%, list=22%, signal=64% RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0001836 RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0001836 16 -0.58208466 -1.4192202 0.072386056 0.1112754 1.0 3841 tags=50%, list=25%, signal=67% RIBOSOMAL LARGE SUBUNIT ASSEMBLY%GOBP%GO:0000027 RIBOSOMAL LARGE SUBUNIT ASSEMBLY%GOBP%GO:0000027 21 -0.53637147 -1.4176365 0.06451613 0.11231698 1.0 4617 tags=48%, list=30%, signal=68% AROMATIC AMINO ACID FAMILY METABOLIC PROCESS%GOBP%GO:0009072 AROMATIC AMINO ACID FAMILY METABOLIC PROCESS%GOBP%GO:0009072 18 -0.57006925 -1.4172306 0.085365854 0.11251888 1.0 2813 tags=44%, list=18%, signal=54% DNA INTEGRITY CHECKPOINT%GOBP%GO:0031570 DNA INTEGRITY CHECKPOINT%GOBP%GO:0031570 131 -0.3796464 -1.4163368 0.0070422534 0.11302541 1.0 3438 tags=34%, list=23%, signal=44% REGULATION OF TUMOR NECROSIS FACTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0010803 REGULATION OF TUMOR NECROSIS FACTOR-MEDIATED SIGNALING PATHWAY%GOBP%GO:0010803 44 -0.46676996 -1.4162813 0.03731343 0.11295917 1.0 2570 tags=34%, list=17%, signal=41% REGULATION OF SISTER CHROMATID SEGREGATION%GOBP%GO:0033045 REGULATION OF SISTER CHROMATID SEGREGATION%GOBP%GO:0033045 56 -0.44245064 -1.4156333 0.027559055 0.11329489 1.0 1817 tags=29%, list=12%, signal=32% RESOLUTION OF D-LOOP STRUCTURES THROUGH HOLLIDAY JUNCTION INTERMEDIATES%REACTOME DATABASE ID RELEASE 60%5693568 RESOLUTION OF D-LOOP STRUCTURES THROUGH HOLLIDAY JUNCTION INTERMEDIATES%REACTOME DATABASE ID RELEASE 60%5693568 26 -0.5245177 -1.4155436 0.05785124 0.11325684 1.0 5059 tags=65%, list=33%, signal=98% CHOLESTEROL BIOSYNTHESIS%REACTOME%R-HSA-191273.4 CHOLESTEROL BIOSYNTHESIS%REACTOME%R-HSA-191273.4 22 -0.5440245 -1.4154725 0.052910052 0.11319201 1.0 1994 tags=32%, list=13%, signal=37% DNA CATABOLIC PROCESS%GOBP%GO:0006308 DNA CATABOLIC PROCESS%GOBP%GO:0006308 19 -0.55789745 -1.4150652 0.09921671 0.1133954 1.0 5134 tags=58%, list=34%, signal=87% APOPTOTIC NUCLEAR CHANGES%GOBP%GO:0030262 APOPTOTIC NUCLEAR CHANGES%GOBP%GO:0030262 20 -0.55429137 -1.4148655 0.08356546 0.11342017 1.0 2881 tags=35%, list=19%, signal=43% PROTEIN AUTOUBIQUITINATION%GOBP%GO:0051865 PROTEIN AUTOUBIQUITINATION%GOBP%GO:0051865 45 -0.46877983 -1.4147288 0.06137184 0.113422036 1.0 5267 tags=44%, list=35%, signal=68% BIOCARTA_G2_PATHWAY%MSIGDB_C2%BIOCARTA_G2_PATHWAY BIOCARTA_G2_PATHWAY%MSIGDB_C2%BIOCARTA_G2_PATHWAY 24 -0.53080595 -1.4144644 0.05775076 0.113482654 1.0 1920 tags=29%, list=13%, signal=33% FAS SIGNALING PATHWAY%PANTHER PATHWAY%P00020 FAS SIGNALING PATHWAY%PANTHER PATHWAY%P00020 30 -0.5113309 -1.414025 0.077380955 0.11370691 1.0 3152 tags=40%, list=21%, signal=50% TELOMERE CAPPING%GOBP%GO:0016233 TELOMERE CAPPING%GOBP%GO:0016233 21 -0.550712 -1.4139984 0.08290155 0.11360245 1.0 5369 tags=57%, list=35%, signal=88% CHROMATIN SILENCING AT RDNA%GOBP%GO:0000183 CHROMATIN SILENCING AT RDNA%GOBP%GO:0000183 21 -0.54436636 -1.4138124 0.07520892 0.113628075 1.0 5369 tags=62%, list=35%, signal=96% DEFENSE RESPONSE TO GRAM-POSITIVE BACTERIUM%GOBP%GO:0050830 DEFENSE RESPONSE TO GRAM-POSITIVE BACTERIUM%GOBP%GO:0050830 23 -0.5413244 -1.4135519 0.07317073 0.113681294 1.0 3332 tags=61%, list=22%, signal=78% CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0016052 CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0016052 75 -0.40885654 -1.4130433 0.0047393367 0.11397332 1.0 4445 tags=35%, list=29%, signal=49% PID_AURORA_B_PATHWAY%MSIGDB_C2%PID_AURORA_B_PATHWAY PID_AURORA_B_PATHWAY%MSIGDB_C2%PID_AURORA_B_PATHWAY 38 -0.46891594 -1.412292 0.03618421 0.114444524 1.0 3079 tags=53%, list=20%, signal=66% REGULATION OF ACTIVATED T CELL PROLIFERATION%GOBP%GO:0046006 REGULATION OF ACTIVATED T CELL PROLIFERATION%GOBP%GO:0046006 23 -0.53484833 -1.4119596 0.06628242 0.11458726 1.0 603 tags=26%, list=4%, signal=27% G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000082 G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000082 93 -0.3921374 -1.4107171 0.02247191 0.11537308 1.0 2567 tags=41%, list=17%, signal=49% NEGATIVE REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0045947 NEGATIVE REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0045947 18 -0.5705079 -1.4101299 0.0875 0.11573687 1.0 4268 tags=50%, list=28%, signal=69% REGULATION OF TNFR1 SIGNALING%REACTOME%R-HSA-5357905.2 REGULATION OF TNFR1 SIGNALING%REACTOME%R-HSA-5357905.2 30 -0.5034263 -1.4096414 0.062091503 0.11600011 1.0 2247 tags=27%, list=15%, signal=31% TRANSCRIPTION FROM RNA POLYMERASE III PROMOTER%GOBP%GO:0006383 TRANSCRIPTION FROM RNA POLYMERASE III PROMOTER%GOBP%GO:0006383 24 -0.5356133 -1.4084737 0.07317073 0.1167995 1.0 3808 tags=42%, list=25%, signal=55% BIOCARTA_HIVNEF_PATHWAY%MSIGDB_C2%BIOCARTA_HIVNEF_PATHWAY BIOCARTA_HIVNEF_PATHWAY%MSIGDB_C2%BIOCARTA_HIVNEF_PATHWAY 57 -0.4351264 -1.4084542 0.029411765 0.116697595 1.0 3245 tags=26%, list=21%, signal=33% FORMATION OF RNA POL II ELONGATION COMPLEX%REACTOME DATABASE ID RELEASE 60%112382 FORMATION OF RNA POL II ELONGATION COMPLEX%REACTOME DATABASE ID RELEASE 60%112382 53 -0.44551408 -1.407629 0.04195804 0.117198795 1.0 2792 tags=30%, list=18%, signal=37% ATF4 ACTIVATES GENES%REACTOME DATABASE ID RELEASE 60%380994 ATF4 ACTIVATES GENES%REACTOME DATABASE ID RELEASE 60%380994 23 -0.53416723 -1.4071814 0.07022472 0.11743804 1.0 554 tags=17%, list=4%, signal=18% PID_MYC_PATHWAY%MSIGDB_C2%PID_MYC_PATHWAY PID_MYC_PATHWAY%MSIGDB_C2%PID_MYC_PATHWAY 24 -0.5304172 -1.4056152 0.06685237 0.11857887 1.0 4701 tags=58%, list=31%, signal=84% LIPOPOLYSACCHARIDE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0031663 LIPOPOLYSACCHARIDE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0031663 15 -0.59446454 -1.4055424 0.07235142 0.1185052 1.0 2124 tags=27%, list=14%, signal=31% POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:1903749 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION%GOBP%GO:1903749 99 -0.3961694 -1.4049823 0.0 0.11885483 1.0 3288 tags=30%, list=22%, signal=38% REGULATION OF CHROMOSOME SEPARATION%GOBP%GO:1905818 REGULATION OF CHROMOSOME SEPARATION%GOBP%GO:1905818 39 -0.4774718 -1.4049114 0.05901639 0.11879511 1.0 1817 tags=33%, list=12%, signal=38% REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042129 REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042129 75 -0.42891523 -1.4045782 0.014084507 0.118934214 1.0 2257 tags=33%, list=15%, signal=39% HEME BIOSYNTHETIC PROCESS%GOBP%GO:0006783 HEME BIOSYNTHETIC PROCESS%GOBP%GO:0006783 15 -0.59711903 -1.4037678 0.07481297 0.119509846 1.0 5005 tags=80%, list=33%, signal=119% HISTONE UBIQUITINATION%GOBP%GO:0016574 HISTONE UBIQUITINATION%GOBP%GO:0016574 30 -0.5022989 -1.4013605 0.06725146 0.121297285 1.0 2310 tags=23%, list=15%, signal=27% POSITIVE REGULATION OF DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0032786 POSITIVE REGULATION OF DNA-TEMPLATED TRANSCRIPTION, ELONGATION%GOBP%GO:0032786 20 -0.54342026 -1.4006275 0.08222812 0.121794574 1.0 3885 tags=40%, list=26%, signal=54% VALIDATED TARGETS OF C-MYC TRANSCRIPTIONAL ACTIVATION%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%VALIDATED TARGETS OF C-MYC TRANSCRIPTIONAL ACTIVATION VALIDATED TARGETS OF C-MYC TRANSCRIPTIONAL ACTIVATION%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%VALIDATED TARGETS OF C-MYC TRANSCRIPTIONAL ACTIVATION 78 -0.4115888 -1.4004692 0.026737968 0.12180954 1.0 2861 tags=32%, list=19%, signal=39% NEGATIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002704 NEGATIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY%GOBP%GO:0002704 20 -0.5592232 -1.4002777 0.07438017 0.1218145 1.0 2135 tags=50%, list=14%, signal=58% REGULATION OF MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0033047 REGULATION OF MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0033047 46 -0.45665422 -1.3989336 0.054054055 0.12279061 1.0 3584 tags=43%, list=24%, signal=57% REGULATION OF MITOTIC SPINDLE ORGANIZATION%GOBP%GO:0060236 REGULATION OF MITOTIC SPINDLE ORGANIZATION%GOBP%GO:0060236 26 -0.5134303 -1.397662 0.0922619 0.12365857 1.0 4293 tags=58%, list=28%, signal=80% GLOBAL GENOME NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0070911 GLOBAL GENOME NUCLEOTIDE-EXCISION REPAIR%GOBP%GO:0070911 32 -0.4892079 -1.397471 0.074074075 0.1236972 1.0 4550 tags=53%, list=30%, signal=76% PID_IL2_STAT5_PATHWAY%MSIGDB_C2%PID_IL2_STAT5_PATHWAY PID_IL2_STAT5_PATHWAY%MSIGDB_C2%PID_IL2_STAT5_PATHWAY 28 -0.5059033 -1.3974328 0.054054055 0.12360382 1.0 1205 tags=29%, list=8%, signal=31% AROMATIC AMINO ACID FAMILY CATABOLIC PROCESS%GOBP%GO:0009074 AROMATIC AMINO ACID FAMILY CATABOLIC PROCESS%GOBP%GO:0009074 17 -0.57664686 -1.3972307 0.0802005 0.123638675 1.0 2813 tags=47%, list=18%, signal=58% LYMPHOCYTE CHEMOTAXIS%GOBP%GO:0048247 LYMPHOCYTE CHEMOTAXIS%GOBP%GO:0048247 32 -0.49317572 -1.3960159 0.07255521 0.124527924 1.0 1660 tags=34%, list=11%, signal=39% OVARIAN TUMOR DOMAIN PROTEASES%REACTOME DATABASE ID RELEASE 60%5689896 OVARIAN TUMOR DOMAIN PROTEASES%REACTOME DATABASE ID RELEASE 60%5689896 38 -0.47358307 -1.3953338 0.06462585 0.12499121 1.0 2525 tags=29%, list=17%, signal=35% PYRUVATE METABOLISM AND CITRIC ACID (TCA) CYCLE%REACTOME DATABASE ID RELEASE 60%71406 PYRUVATE METABOLISM AND CITRIC ACID (TCA) CYCLE%REACTOME DATABASE ID RELEASE 60%71406 43 -0.4563699 -1.3949862 0.036544852 0.12510592 1.0 5025 tags=56%, list=33%, signal=83% ALPHA-AMINO ACID CATABOLIC PROCESS%GOBP%GO:1901606 ALPHA-AMINO ACID CATABOLIC PROCESS%GOBP%GO:1901606 64 -0.4376164 -1.3947821 0.049382716 0.12513241 1.0 3921 tags=42%, list=26%, signal=57% CHOLESTEROL EFFLUX%GOBP%GO:0033344 CHOLESTEROL EFFLUX%GOBP%GO:0033344 17 -0.5619097 -1.394756 0.08746356 0.12502566 1.0 1328 tags=24%, list=9%, signal=26% POSITIVE REGULATION OF NIK/NF-KAPPAB SIGNALING%GOBP%GO:1901224 POSITIVE REGULATION OF NIK/NF-KAPPAB SIGNALING%GOBP%GO:1901224 31 -0.49044886 -1.3942304 0.052469134 0.12530343 1.0 849 tags=16%, list=6%, signal=17% TNFSF1%IOB%TNFSF1 TNFSF1%IOB%TNFSF1 17 -0.56465656 -1.3932405 0.0961039 0.12594382 1.0 1888 tags=35%, list=12%, signal=40% NUCLEOTIDE-EXCISION REPAIR, PREINCISION COMPLEX ASSEMBLY%GOBP%GO:0006294 NUCLEOTIDE-EXCISION REPAIR, PREINCISION COMPLEX ASSEMBLY%GOBP%GO:0006294 29 -0.49662593 -1.393125 0.07339449 0.12591311 1.0 4550 tags=52%, list=30%, signal=74% REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS%GOBP%GO:1903409 REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS%GOBP%GO:1903409 15 -0.5700413 -1.3912934 0.10526316 0.12726356 1.0 488 tags=27%, list=3%, signal=28% INTRACELLULAR TRANSPORT OF VIRUS%GOBP%GO:0075733 INTRACELLULAR TRANSPORT OF VIRUS%GOBP%GO:0075733 48 -0.44852608 -1.390799 0.042145595 0.12756446 1.0 4440 tags=48%, list=29%, signal=67% POSITIVE REGULATION OF B CELL PROLIFERATION%GOBP%GO:0030890 POSITIVE REGULATION OF B CELL PROLIFERATION%GOBP%GO:0030890 19 -0.5522326 -1.3906002 0.09859155 0.1275856 1.0 3843 tags=53%, list=25%, signal=70% IL2 SIGNALING EVENTS MEDIATED BY STAT5%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL2 SIGNALING EVENTS MEDIATED BY STAT5 IL2 SIGNALING EVENTS MEDIATED BY STAT5%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL2 SIGNALING EVENTS MEDIATED BY STAT5 28 -0.5059033 -1.3901864 0.058139537 0.12776218 1.0 1205 tags=29%, list=8%, signal=31% NECROPTOTIC PROCESS%GOBP%GO:0070266 NECROPTOTIC PROCESS%GOBP%GO:0070266 17 -0.57464933 -1.3870865 0.10050251 0.13032426 1.0 2314 tags=29%, list=15%, signal=35% MITOCHONDRIAL ELECTRON TRANSPORT, CYTOCHROME C TO OXYGEN%GOBP%GO:0006123 MITOCHONDRIAL ELECTRON TRANSPORT, CYTOCHROME C TO OXYGEN%GOBP%GO:0006123 15 -0.58381665 -1.3864189 0.094527364 0.13079187 1.0 1680 tags=40%, list=11%, signal=45% FERTILIZATION%GOBP%GO:0009566 FERTILIZATION%GOBP%GO:0009566 36 -0.46909893 -1.386306 0.061594203 0.13074729 1.0 2546 tags=22%, list=17%, signal=27% NUCLEOBASE-CONTAINING SMALL MOLECULE INTERCONVERSION%GOBP%GO:0015949 NUCLEOBASE-CONTAINING SMALL MOLECULE INTERCONVERSION%GOBP%GO:0015949 26 -0.51834226 -1.3858758 0.064705886 0.130949 1.0 3640 tags=62%, list=24%, signal=81% TNF SIGNALING%REACTOME%R-HSA-75893.4 TNF SIGNALING%REACTOME%R-HSA-75893.4 40 -0.46427307 -1.3849722 0.03416149 0.13160016 1.0 2600 tags=23%, list=17%, signal=27% REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY%GOBP%GO:0046902 REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY%GOBP%GO:0046902 58 -0.41869143 -1.3843542 0.036363635 0.13200231 1.0 4118 tags=34%, list=27%, signal=47% INTRACELLULAR PH REDUCTION%GOBP%GO:0051452 INTRACELLULAR PH REDUCTION%GOBP%GO:0051452 34 -0.47279054 -1.3832102 0.053968254 0.13277572 1.0 4520 tags=44%, list=30%, signal=63% REGULATION OF NUCLEASE ACTIVITY%GOBP%GO:0032069 REGULATION OF NUCLEASE ACTIVITY%GOBP%GO:0032069 24 -0.52461946 -1.3828514 0.08595989 0.13293567 1.0 641 tags=21%, list=4%, signal=22% BIOCARTA_MITOCHONDRIA_PATHWAY%MSIGDB_C2%BIOCARTA_MITOCHONDRIA_PATHWAY BIOCARTA_MITOCHONDRIA_PATHWAY%MSIGDB_C2%BIOCARTA_MITOCHONDRIA_PATHWAY 21 -0.55300474 -1.3817378 0.09695291 0.1336989 1.0 4190 tags=48%, list=28%, signal=66% PTERIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0042558 PTERIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0042558 24 -0.52038985 -1.3808644 0.10344828 0.13434762 1.0 3921 tags=42%, list=26%, signal=56% OTHER INTERLEUKIN SIGNALING%REACTOME DATABASE ID RELEASE 60%449836 OTHER INTERLEUKIN SIGNALING%REACTOME DATABASE ID RELEASE 60%449836 23 -0.52923864 -1.379108 0.08493151 0.1357196 1.0 1373 tags=26%, list=9%, signal=29% PERK REGULATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 60%381042 PERK REGULATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 60%381042 26 -0.5041557 -1.379008 0.087878786 0.13566615 1.0 554 tags=15%, list=4%, signal=16% MONOCARBOXYLIC ACID CATABOLIC PROCESS%GOBP%GO:0072329 MONOCARBOXYLIC ACID CATABOLIC PROCESS%GOBP%GO:0072329 76 -0.39900294 -1.3773791 0.030927835 0.13697918 1.0 3144 tags=41%, list=21%, signal=51% DETOXIFICATION%GOBP%GO:0098754 DETOXIFICATION%GOBP%GO:0098754 15 -0.5625705 -1.3773677 0.10123457 0.13684787 1.0 5222 tags=60%, list=34%, signal=91% HALLMARK_FATTY_ACID_METABOLISM%MSIGDB_C2%HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM%MSIGDB_C2%HALLMARK_FATTY_ACID_METABOLISM 142 -0.37484047 -1.3759247 0.007575758 0.13792254 1.0 3063 tags=36%, list=20%, signal=45% REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0006446 REGULATION OF TRANSLATIONAL INITIATION%GOBP%GO:0006446 60 -0.42703223 -1.3755648 0.04511278 0.1380949 1.0 2487 tags=22%, list=16%, signal=26% REGULATION OF MRNA PROCESSING%GOBP%GO:0050684 REGULATION OF MRNA PROCESSING%GOBP%GO:0050684 61 -0.42119697 -1.3755364 0.07531381 0.1379735 1.0 4235 tags=31%, list=28%, signal=43% MITOTIC SPINDLE ASSEMBLY%GOBP%GO:0090307 MITOTIC SPINDLE ASSEMBLY%GOBP%GO:0090307 38 -0.46519285 -1.3753309 0.053511705 0.13801658 1.0 2741 tags=34%, list=18%, signal=42% HALLMARK_PEROXISOME%MSIGDB_C2%HALLMARK_PEROXISOME HALLMARK_PEROXISOME%MSIGDB_C2%HALLMARK_PEROXISOME 94 -0.38237226 -1.3747324 0.011627907 0.13842161 1.0 4088 tags=40%, list=27%, signal=55% COENZYME BIOSYNTHETIC PROCESS%GOBP%GO:0009108 COENZYME BIOSYNTHETIC PROCESS%GOBP%GO:0009108 87 -0.3974977 -1.3747277 0.026041666 0.1382852 1.0 3663 tags=43%, list=24%, signal=56% REGULATION OF CELL CYCLE CHECKPOINT%GOBP%GO:1901976 REGULATION OF CELL CYCLE CHECKPOINT%GOBP%GO:1901976 24 -0.5182021 -1.3739097 0.08959538 0.13892017 1.0 3885 tags=54%, list=26%, signal=73% REGULATION OF INTERLEUKIN-17 PRODUCTION%GOBP%GO:0032660 REGULATION OF INTERLEUKIN-17 PRODUCTION%GOBP%GO:0032660 15 -0.58186084 -1.3733791 0.11340206 0.13923852 1.0 3555 tags=67%, list=23%, signal=87% PH REDUCTION%GOBP%GO:0045851 PH REDUCTION%GOBP%GO:0045851 35 -0.46274 -1.3728919 0.070512824 0.13951142 1.0 4520 tags=43%, list=30%, signal=61% MRNA CAPPING%REACTOME%R-HSA-72086.3 MRNA CAPPING%REACTOME%R-HSA-72086.3 29 -0.50056064 -1.3719835 0.09855072 0.14019614 1.0 2682 tags=34%, list=18%, signal=42% TETRAPYRROLE METABOLIC PROCESS%GOBP%GO:0033013 TETRAPYRROLE METABOLIC PROCESS%GOBP%GO:0033013 38 -0.46434823 -1.3716255 0.07210031 0.14039628 1.0 3087 tags=39%, list=20%, signal=49% REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043370 REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043370 22 -0.5273977 -1.3713558 0.08791209 0.14047778 1.0 2140 tags=36%, list=14%, signal=42% POSITIVE REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043372 POSITIVE REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043372 16 -0.57229286 -1.3713493 0.111959286 0.14034319 1.0 2140 tags=44%, list=14%, signal=51% REPLICATION FORK PROCESSING%GOBP%GO:0031297 REPLICATION FORK PROCESSING%GOBP%GO:0031297 23 -0.507243 -1.3712573 0.07941177 0.14029023 1.0 4993 tags=52%, list=33%, signal=78% RNA CAPPING%GOBP%GO:0036260 RNA CAPPING%GOBP%GO:0036260 31 -0.48408374 -1.370298 0.09253731 0.14108787 1.0 4053 tags=45%, list=27%, signal=61% LYMPHOCYTE HOMEOSTASIS%GOBP%GO:0002260 LYMPHOCYTE HOMEOSTASIS%GOBP%GO:0002260 16 -0.5713478 -1.3691232 0.08801956 0.14208543 1.0 2135 tags=31%, list=14%, signal=36% LOSS OF PROTEINS REQUIRED FOR INTERPHASE MICROTUBULE ORGANIZATION FROM THE CENTROSOME%REACTOME%R-HSA-380284.1 LOSS OF PROTEINS REQUIRED FOR INTERPHASE MICROTUBULE ORGANIZATION FROM THE CENTROSOME%REACTOME%R-HSA-380284.1 61 -0.42345136 -1.3688831 0.015686275 0.14217363 1.0 1827 tags=21%, list=12%, signal=24% CD40%IOB%CD40 CD40%IOB%CD40 26 -0.49725878 -1.3686017 0.0851735 0.14228892 1.0 2486 tags=31%, list=16%, signal=37% LOSS OF NLP FROM MITOTIC CENTROSOMES%REACTOME DATABASE ID RELEASE 60%380259 LOSS OF NLP FROM MITOTIC CENTROSOMES%REACTOME DATABASE ID RELEASE 60%380259 61 -0.42345136 -1.3676937 0.054393306 0.14295946 1.0 1827 tags=21%, list=12%, signal=24% POSITIVE REGULATION OF INTERLEUKIN-12 PRODUCTION%GOBP%GO:0032735 POSITIVE REGULATION OF INTERLEUKIN-12 PRODUCTION%GOBP%GO:0032735 20 -0.538399 -1.3676832 0.10541311 0.14283063 1.0 2140 tags=40%, list=14%, signal=46% REGULATION OF ESTABLISHMENT OF PLANAR POLARITY%GOBP%GO:0090175 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY%GOBP%GO:0090175 90 -0.3986782 -1.3669878 0.04 0.14329928 1.0 1584 tags=29%, list=10%, signal=32% PYRIMIDINE-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0072528 PYRIMIDINE-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0072528 21 -0.5354804 -1.3659607 0.11494253 0.14404806 1.0 1384 tags=38%, list=9%, signal=42% MACROAUTOPHAGY%GOBP%GO:0016236 MACROAUTOPHAGY%GOBP%GO:0016236 119 -0.371879 -1.3644884 0.0125 0.14526945 1.0 3780 tags=30%, list=25%, signal=40% POSITIVE REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903902 POSITIVE REGULATION OF VIRAL LIFE CYCLE%GOBP%GO:1903902 48 -0.4390358 -1.3642765 0.048 0.14532498 1.0 3729 tags=42%, list=25%, signal=55% POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032212 POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032212 32 -0.4676653 -1.3625953 0.08169935 0.14669064 1.0 5259 tags=59%, list=35%, signal=91% POSITIVE REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042102 POSITIVE REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042102 51 -0.43214402 -1.3620845 0.06844106 0.14701895 1.0 2570 tags=39%, list=17%, signal=47% PID_TRAIL_PATHWAY%MSIGDB_C2%PID_TRAIL_PATHWAY PID_TRAIL_PATHWAY%MSIGDB_C2%PID_TRAIL_PATHWAY 28 -0.49138364 -1.3600976 0.08857143 0.14871252 1.0 3621 tags=46%, list=24%, signal=61% REGULATION OF MITOTIC METAPHASE/ANAPHASE TRANSITION%GOBP%GO:0030071 REGULATION OF MITOTIC METAPHASE/ANAPHASE TRANSITION%GOBP%GO:0030071 36 -0.46452603 -1.3587749 0.0779661 0.14978728 1.0 1817 tags=33%, list=12%, signal=38% AXONEME ASSEMBLY%GOBP%GO:0035082 AXONEME ASSEMBLY%GOBP%GO:0035082 31 -0.47141585 -1.3574907 0.06583072 0.15086854 1.0 5981 tags=52%, list=39%, signal=85% DNA DUPLEX UNWINDING%GOBP%GO:0032508 DNA DUPLEX UNWINDING%GOBP%GO:0032508 36 -0.46353167 -1.3574225 0.097222224 0.15077241 1.0 4550 tags=53%, list=30%, signal=75% ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION%REACTOME DATABASE ID RELEASE 60%450302 ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION%REACTOME DATABASE ID RELEASE 60%450302 19 -0.5374757 -1.3570695 0.10178117 0.15096536 1.0 2310 tags=32%, list=15%, signal=37% LYMPHOCYTE MIGRATION%GOBP%GO:0072676 LYMPHOCYTE MIGRATION%GOBP%GO:0072676 42 -0.4451014 -1.3566701 0.06711409 0.1511856 1.0 1950 tags=31%, list=13%, signal=35% IL2 SIGNALING EVENTS MEDIATED BY PI3K%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL2 SIGNALING EVENTS MEDIATED BY PI3K IL2 SIGNALING EVENTS MEDIATED BY PI3K%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL2 SIGNALING EVENTS MEDIATED BY PI3K 35 -0.4651604 -1.3560575 0.08305648 0.15157382 1.0 3007 tags=29%, list=20%, signal=36% AUTOPHAGY%GOBP%GO:0006914 AUTOPHAGY%GOBP%GO:0006914 152 -0.36400813 -1.356046 0.0 0.15142974 1.0 3836 tags=30%, list=25%, signal=40% SINGLE-ORGANISM CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0044724 SINGLE-ORGANISM CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0044724 72 -0.40012586 -1.3547009 0.052863438 0.15248372 1.0 4445 tags=33%, list=29%, signal=47% POSITIVE REGULATION OF MULTI-ORGANISM PROCESS%GOBP%GO:0043902 POSITIVE REGULATION OF MULTI-ORGANISM PROCESS%GOBP%GO:0043902 141 -0.36523393 -1.3543587 0.017391304 0.152621 1.0 3780 tags=36%, list=25%, signal=48% RNA POLYMERASE III TRANSCRIPTION TERMINATION%REACTOME DATABASE ID RELEASE 60%73980 RNA POLYMERASE III TRANSCRIPTION TERMINATION%REACTOME DATABASE ID RELEASE 60%73980 23 -0.5180645 -1.353852 0.08423913 0.15293702 1.0 3200 tags=39%, list=21%, signal=49% VIRION ASSEMBLY%GOBP%GO:0019068 VIRION ASSEMBLY%GOBP%GO:0019068 35 -0.46951836 -1.3533969 0.07491857 0.15320711 1.0 4440 tags=43%, list=29%, signal=60% SINGLE FERTILIZATION%GOBP%GO:0007338 SINGLE FERTILIZATION%GOBP%GO:0007338 30 -0.48784873 -1.3533504 0.074074075 0.15311506 1.0 2546 tags=27%, list=17%, signal=32% BIOCARTA_RAS_PATHWAY%MSIGDB_C2%BIOCARTA_RAS_PATHWAY BIOCARTA_RAS_PATHWAY%MSIGDB_C2%BIOCARTA_RAS_PATHWAY 23 -0.5242549 -1.3518482 0.101123594 0.15437682 1.0 3959 tags=43%, list=26%, signal=59% PID_MYC_ACTIV_PATHWAY%MSIGDB_C2%PID_MYC_ACTIV_PATHWAY PID_MYC_ACTIV_PATHWAY%MSIGDB_C2%PID_MYC_ACTIV_PATHWAY 77 -0.39530256 -1.3503013 0.033816423 0.15569022 1.0 2861 tags=30%, list=19%, signal=37% INTRINSIC PATHWAY FOR APOPTOSIS%REACTOME DATABASE ID RELEASE 60%109606 INTRINSIC PATHWAY FOR APOPTOSIS%REACTOME DATABASE ID RELEASE 60%109606 43 -0.45167854 -1.350066 0.07534247 0.15574989 1.0 2172 tags=23%, list=14%, signal=27% GPI ANCHOR BIOSYNTHETIC PROCESS%GOBP%GO:0006506 GPI ANCHOR BIOSYNTHETIC PROCESS%GOBP%GO:0006506 29 -0.47891608 -1.3495877 0.09677419 0.15601932 1.0 4425 tags=38%, list=29%, signal=53% NEGATIVE REGULATION OF T CELL ACTIVATION%GOBP%GO:0050868 NEGATIVE REGULATION OF T CELL ACTIVATION%GOBP%GO:0050868 48 -0.4423938 -1.3494102 0.06844106 0.1560493 1.0 2135 tags=40%, list=14%, signal=46% BIOCARTA_FMLP_PATHWAY%MSIGDB_C2%BIOCARTA_FMLP_PATHWAY BIOCARTA_FMLP_PATHWAY%MSIGDB_C2%BIOCARTA_FMLP_PATHWAY 34 -0.4782097 -1.3493176 0.10064935 0.15598825 1.0 1507 tags=18%, list=10%, signal=20% NEGATIVE REGULATION OF LEUKOCYTE ACTIVATION%GOBP%GO:0002695 NEGATIVE REGULATION OF LEUKOCYTE ACTIVATION%GOBP%GO:0002695 68 -0.40528736 -1.34929 0.027559055 0.15585998 1.0 2363 tags=40%, list=16%, signal=47% TRISTETRAPROLIN (TTP, ZFP36) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450513.2 TRISTETRAPROLIN (TTP, ZFP36) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450513.2 16 -0.5609057 -1.3489326 0.13947369 0.15604892 1.0 1022 tags=25%, list=7%, signal=27% PIGMENT BIOSYNTHETIC PROCESS%GOBP%GO:0046148 PIGMENT BIOSYNTHETIC PROCESS%GOBP%GO:0046148 28 -0.49541444 -1.3488932 0.103975534 0.1559453 1.0 2822 tags=39%, list=19%, signal=48% SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS%REACTOME%R-HSA-4551638.4 SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS%REACTOME%R-HSA-4551638.4 55 -0.41598567 -1.3480506 0.053435113 0.15661144 1.0 4293 tags=42%, list=28%, signal=58% REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032204 REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032204 69 -0.38979355 -1.3473387 0.047413792 0.15715508 1.0 4527 tags=42%, list=30%, signal=60% REGULATION OF METAPHASE/ANAPHASE TRANSITION OF CELL CYCLE%GOBP%GO:1902099 REGULATION OF METAPHASE/ANAPHASE TRANSITION OF CELL CYCLE%GOBP%GO:1902099 36 -0.46452603 -1.3469468 0.08303249 0.15737292 1.0 1817 tags=33%, list=12%, signal=38% DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR (BCR)%REACTOME DATABASE ID RELEASE 60%1168372 DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR (BCR)%REACTOME DATABASE ID RELEASE 60%1168372 165 -0.3492771 -1.346908 0.009009009 0.15727423 1.0 2252 tags=27%, list=15%, signal=31% FOXO FAMILY SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXO FAMILY SIGNALING FOXO FAMILY SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXO FAMILY SIGNALING 47 -0.4282956 -1.3456932 0.062271062 0.1583227 1.0 2178 tags=23%, list=14%, signal=27% CYTOPLASMIC TRANSLATION%GOBP%GO:0002181 CYTOPLASMIC TRANSLATION%GOBP%GO:0002181 26 -0.49350548 -1.3450041 0.074074075 0.15882702 1.0 4513 tags=46%, list=30%, signal=66% REGULATION OF MEMBRANE PERMEABILITY%GOBP%GO:0090559 REGULATION OF MEMBRANE PERMEABILITY%GOBP%GO:0090559 62 -0.41766247 -1.3448985 0.03587444 0.15878111 1.0 4118 tags=34%, list=27%, signal=46% TRNA METHYLATION%GOBP%GO:0030488 TRNA METHYLATION%GOBP%GO:0030488 15 -0.5778371 -1.3448932 0.12171838 0.15863451 1.0 3158 tags=33%, list=21%, signal=42% REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR%GOBP%GO:1902253 REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR%GOBP%GO:1902253 18 -0.5488657 -1.3448128 0.11025641 0.15857174 1.0 2951 tags=33%, list=19%, signal=41% POSITIVE REGULATION OF CYTOKINESIS%GOBP%GO:0032467 POSITIVE REGULATION OF CYTOKINESIS%GOBP%GO:0032467 23 -0.5144643 -1.3447306 0.10752688 0.15851055 1.0 4083 tags=43%, list=27%, signal=59% LINOLEIC ACID METABOLIC PROCESS%GOBP%GO:0043651 LINOLEIC ACID METABOLIC PROCESS%GOBP%GO:0043651 15 -0.5678203 -1.3444283 0.11922141 0.15864454 1.0 1949 tags=40%, list=13%, signal=46% NEGATIVE REGULATION OF PROTEASOMAL UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0032435 NEGATIVE REGULATION OF PROTEASOMAL UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0032435 16 -0.56562513 -1.3438011 0.120300755 0.15907027 1.0 4930 tags=50%, list=32%, signal=74% GPI ANCHOR METABOLIC PROCESS%GOBP%GO:0006505 GPI ANCHOR METABOLIC PROCESS%GOBP%GO:0006505 31 -0.46860862 -1.3435893 0.083333336 0.15911268 1.0 4425 tags=35%, list=29%, signal=50% SIGNALING BY HEDGEHOG%REACTOME%R-HSA-5358351.2 SIGNALING BY HEDGEHOG%REACTOME%R-HSA-5358351.2 129 -0.3678419 -1.3432558 0.0074626864 0.15928423 1.0 1616 tags=19%, list=11%, signal=21% PROGRAMMED NECROTIC CELL DEATH%GOBP%GO:0097300 PROGRAMMED NECROTIC CELL DEATH%GOBP%GO:0097300 19 -0.5253594 -1.3419964 0.10481586 0.16034257 1.0 2314 tags=26%, list=15%, signal=31% MITOCHONDRION DISASSEMBLY%GOBP%GO:0061726 MITOCHONDRION DISASSEMBLY%GOBP%GO:0061726 28 -0.48193738 -1.3403157 0.117117114 0.16187485 1.0 2834 tags=21%, list=19%, signal=26% T CELL ACTIVATION%PANTHER PATHWAY%P00053 T CELL ACTIVATION%PANTHER PATHWAY%P00053 62 -0.40933728 -1.339724 0.044176705 0.16229965 1.0 1950 tags=29%, list=13%, signal=33% MEIOTIC SYNAPSIS%REACTOME DATABASE ID RELEASE 60%1221632 MEIOTIC SYNAPSIS%REACTOME DATABASE ID RELEASE 60%1221632 48 -0.42122132 -1.3395047 0.053511705 0.16237713 1.0 3319 tags=42%, list=22%, signal=53% BIOCARTA_RELA_PATHWAY%MSIGDB_C2%BIOCARTA_RELA_PATHWAY BIOCARTA_RELA_PATHWAY%MSIGDB_C2%BIOCARTA_RELA_PATHWAY 16 -0.56826544 -1.3385531 0.15176152 0.16316727 1.0 4286 tags=50%, list=28%, signal=70% B CELL ACTIVATION%REACTOME%R-HSA-983705.1 B CELL ACTIVATION%REACTOME%R-HSA-983705.1 194 -0.34321347 -1.3380479 0.0 0.16353834 1.0 2252 tags=27%, list=15%, signal=31% RESOLUTION OF D-LOOP STRUCTURES THROUGH SYNTHESIS-DEPENDENT STRAND ANNEALING (SDSA)%REACTOME DATABASE ID RELEASE 60%5693554 RESOLUTION OF D-LOOP STRUCTURES THROUGH SYNTHESIS-DEPENDENT STRAND ANNEALING (SDSA)%REACTOME DATABASE ID RELEASE 60%5693554 23 -0.5062578 -1.337994 0.10714286 0.16342957 1.0 5059 tags=65%, list=33%, signal=98% POSITIVE REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0045815 POSITIVE REGULATION OF GENE EXPRESSION, EPIGENETIC%GOBP%GO:0045815 59 -0.40741292 -1.3378508 0.05668016 0.16339125 1.0 3762 tags=36%, list=25%, signal=47% PORPHYRIN-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0006779 PORPHYRIN-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0006779 17 -0.5546253 -1.3372809 0.12919897 0.1637675 1.0 3557 tags=53%, list=23%, signal=69% POSITIVE REGULATION OF CYTOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0001961 POSITIVE REGULATION OF CYTOKINE-MEDIATED SIGNALING PATHWAY%GOBP%GO:0001961 21 -0.52260256 -1.3370944 0.10335196 0.16380972 1.0 2327 tags=29%, list=15%, signal=34% METHIONINE METABOLIC PROCESS%GOBP%GO:0006555 METHIONINE METABOLIC PROCESS%GOBP%GO:0006555 17 -0.5442733 -1.3361137 0.102870815 0.16459888 1.0 5021 tags=71%, list=33%, signal=105% PID_ATM_PATHWAY%MSIGDB_C2%PID_ATM_PATHWAY PID_ATM_PATHWAY%MSIGDB_C2%PID_ATM_PATHWAY 34 -0.45840383 -1.3352717 0.11821086 0.16523941 1.0 2455 tags=29%, list=16%, signal=35% POSITIVE REGULATION OF I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0043123 POSITIVE REGULATION OF I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0043123 156 -0.35265803 -1.3352493 0.0 0.16511016 1.0 2405 tags=26%, list=16%, signal=31% NUCLEOBASE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%8956320 NUCLEOBASE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%8956320 15 -0.5849591 -1.3352226 0.13868614 0.16497296 1.0 1384 tags=20%, list=9%, signal=22% MITOPHAGY%GOBP%GO:0000422 MITOPHAGY%GOBP%GO:0000422 28 -0.48193738 -1.3350877 0.10619469 0.16494705 1.0 2834 tags=21%, list=19%, signal=26% 7-METHYLGUANOSINE RNA CAPPING%GOBP%GO:0009452 7-METHYLGUANOSINE RNA CAPPING%GOBP%GO:0009452 30 -0.48292774 -1.334881 0.09904154 0.16500448 1.0 2682 tags=33%, list=18%, signal=40% POSITIVE REGULATION OF ENDOPEPTIDASE ACTIVITY%GOBP%GO:0010950 POSITIVE REGULATION OF ENDOPEPTIDASE ACTIVITY%GOBP%GO:0010950 103 -0.37058058 -1.334532 0.018518519 0.16523014 1.0 1315 tags=18%, list=9%, signal=20% HISTONE PHOSPHORYLATION%GOBP%GO:0016572 HISTONE PHOSPHORYLATION%GOBP%GO:0016572 18 -0.53111476 -1.3341504 0.13032581 0.16548422 1.0 2746 tags=39%, list=18%, signal=47% FOLIC ACID-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0006760 FOLIC ACID-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0006760 21 -0.5043634 -1.3338791 0.123893805 0.16558601 1.0 2654 tags=29%, list=17%, signal=35% DENDRITIC CELL DIFFERENTIATION%GOBP%GO:0097028 DENDRITIC CELL DIFFERENTIATION%GOBP%GO:0097028 16 -0.552587 -1.333852 0.11369509 0.16545992 1.0 2195 tags=44%, list=14%, signal=51% G-CSF%IOB%G-CSF G-CSF%IOB%G-CSF 43 -0.43563405 -1.3336982 0.07508533 0.16544783 1.0 3644 tags=37%, list=24%, signal=49% REGULATION OF GENE SILENCING%GOBP%GO:0060968 REGULATION OF GENE SILENCING%GOBP%GO:0060968 102 -0.37052077 -1.3330891 0.03409091 0.16592446 1.0 4337 tags=45%, list=29%, signal=63% REGULATION OF ALTERNATIVE MRNA SPLICING, VIA SPLICEOSOME%GOBP%GO:0000381 REGULATION OF ALTERNATIVE MRNA SPLICING, VIA SPLICEOSOME%GOBP%GO:0000381 23 -0.5132773 -1.3326807 0.08450704 0.16615844 1.0 4483 tags=43%, list=29%, signal=62% ROS, RNS PRODUCTION IN PHAGOCYTES%REACTOME%R-HSA-1222556.6 ROS, RNS PRODUCTION IN PHAGOCYTES%REACTOME%R-HSA-1222556.6 28 -0.48980954 -1.3326168 0.11940298 0.1660672 1.0 4520 tags=50%, list=30%, signal=71% POSTTRANSCRIPTIONAL GENE SILENCING BY RNA%GOBP%GO:0035194 POSTTRANSCRIPTIONAL GENE SILENCING BY RNA%GOBP%GO:0035194 36 -0.4455443 -1.3323877 0.10034602 0.16612731 1.0 2940 tags=33%, list=19%, signal=41% AURORA B SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%AURORA B SIGNALING AURORA B SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%AURORA B SIGNALING 37 -0.46024635 -1.332093 0.07836991 0.16624707 1.0 3079 tags=51%, list=20%, signal=64% ESTABLISHMENT OF SPINDLE LOCALIZATION%GOBP%GO:0051293 ESTABLISHMENT OF SPINDLE LOCALIZATION%GOBP%GO:0051293 21 -0.5106691 -1.3304363 0.09703504 0.16768359 1.0 2256 tags=33%, list=15%, signal=39% SOMATIC DIVERSIFICATION OF IMMUNOGLOBULINS%GOBP%GO:0016445 SOMATIC DIVERSIFICATION OF IMMUNOGLOBULINS%GOBP%GO:0016445 16 -0.5540256 -1.3303297 0.13202934 0.16764612 1.0 2970 tags=38%, list=20%, signal=47% 7-METHYLGUANOSINE MRNA CAPPING%GOBP%GO:0006370 7-METHYLGUANOSINE MRNA CAPPING%GOBP%GO:0006370 30 -0.48292774 -1.3298137 0.103975534 0.16797057 1.0 2682 tags=33%, list=18%, signal=40% NUCLEOTIDE-EXCISION REPAIR, DNA DUPLEX UNWINDING%GOBP%GO:0000717 NUCLEOTIDE-EXCISION REPAIR, DNA DUPLEX UNWINDING%GOBP%GO:0000717 22 -0.50860715 -1.3286885 0.11173184 0.16895878 1.0 4550 tags=59%, list=30%, signal=84% STRAND DISPLACEMENT%GOBP%GO:0000732 STRAND DISPLACEMENT%GOBP%GO:0000732 23 -0.5062578 -1.3286434 0.11581921 0.1688475 1.0 5059 tags=65%, list=33%, signal=98% CANONICAL NF-KAPPAB PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CANONICAL NF-KAPPAB PATHWAY CANONICAL NF-KAPPAB PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CANONICAL NF-KAPPAB PATHWAY 23 -0.49883702 -1.3260818 0.10215054 0.1712078 1.0 3392 tags=48%, list=22%, signal=61% PRODUCTION OF SMALL RNA INVOLVED IN GENE SILENCING BY RNA%GOBP%GO:0070918 PRODUCTION OF SMALL RNA INVOLVED IN GENE SILENCING BY RNA%GOBP%GO:0070918 18 -0.53204656 -1.3221495 0.12664908 0.17495082 1.0 2940 tags=39%, list=19%, signal=48% GLUCONEOGENESIS%GOBP%GO:0006094 GLUCONEOGENESIS%GOBP%GO:0006094 34 -0.45165738 -1.3219638 0.10031348 0.17498083 1.0 3546 tags=32%, list=23%, signal=42% BETA-CATENIN INDEPENDENT WNT SIGNALING%REACTOME%R-HSA-3858494.3 BETA-CATENIN INDEPENDENT WNT SIGNALING%REACTOME%R-HSA-3858494.3 131 -0.35617083 -1.3215072 0.00729927 0.17531475 1.0 1248 tags=20%, list=8%, signal=21% MONOSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0046365 MONOSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0046365 48 -0.43062547 -1.3213518 0.09051724 0.17529316 1.0 4344 tags=40%, list=29%, signal=55% FEMALE GAMETE GENERATION%GOBP%GO:0007292 FEMALE GAMETE GENERATION%GOBP%GO:0007292 23 -0.49540037 -1.320628 0.11077844 0.17592917 1.0 4518 tags=52%, list=30%, signal=74% POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION%GOBP%GO:1901989 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION%GOBP%GO:1901989 42 -0.43963748 -1.3203757 0.065789476 0.17601843 1.0 2435 tags=36%, list=16%, signal=42% POSITIVE REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032206 POSITIVE REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032206 44 -0.4361493 -1.320068 0.08148148 0.17618488 1.0 5259 tags=52%, list=35%, signal=80% POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY%GOBP%GO:0090263 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY%GOBP%GO:0090263 95 -0.37819412 -1.319808 0.015957447 0.17629933 1.0 1584 tags=25%, list=10%, signal=28% REGULATION OF PROTEIN OLIGOMERIZATION%GOBP%GO:0032459 REGULATION OF PROTEIN OLIGOMERIZATION%GOBP%GO:0032459 25 -0.49346197 -1.3196214 0.11747851 0.17631216 1.0 1867 tags=20%, list=12%, signal=23% PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:0006626 PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:0006626 42 -0.44903767 -1.3193482 0.079422385 0.17645063 1.0 4225 tags=50%, list=28%, signal=69% REGULATION OF SPINDLE CHECKPOINT%GOBP%GO:0090231 REGULATION OF SPINDLE CHECKPOINT%GOBP%GO:0090231 15 -0.5649641 -1.318267 0.16129032 0.17742772 1.0 1780 tags=40%, list=12%, signal=45% INACTIVATION, RECOVERY AND REGULATION OF THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 60%2514859 INACTIVATION, RECOVERY AND REGULATION OF THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 60%2514859 19 -0.524201 -1.3181777 0.10784314 0.17735341 1.0 754 tags=16%, list=5%, signal=17% ST_B_CELL_ANTIGEN_RECEPTOR%MSIGDB_C2%ST_B_CELL_ANTIGEN_RECEPTOR ST_B_CELL_ANTIGEN_RECEPTOR%MSIGDB_C2%ST_B_CELL_ANTIGEN_RECEPTOR 38 -0.44152626 -1.3164699 0.08208955 0.17893733 1.0 3228 tags=34%, list=21%, signal=43% POSITIVE REGULATION OF TOR SIGNALING%GOBP%GO:0032008 POSITIVE REGULATION OF TOR SIGNALING%GOBP%GO:0032008 22 -0.5087182 -1.3152654 0.11111111 0.1799656 1.0 4173 tags=32%, list=27%, signal=44% SELENOAMINO ACID METABOLISM%REACTOME%R-HSA-2408522.2 SELENOAMINO ACID METABOLISM%REACTOME%R-HSA-2408522.2 110 -0.36701068 -1.3150574 0.02366864 0.18002123 1.0 6240 tags=65%, list=41%, signal=110% BIOCARTA_CERAMIDE_PATHWAY%MSIGDB_C2%BIOCARTA_CERAMIDE_PATHWAY BIOCARTA_CERAMIDE_PATHWAY%MSIGDB_C2%BIOCARTA_CERAMIDE_PATHWAY 22 -0.5048109 -1.3128725 0.112716764 0.18216802 1.0 3841 tags=41%, list=25%, signal=55% TRAIL SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TRAIL SIGNALING PATHWAY TRAIL SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%TRAIL SIGNALING PATHWAY 25 -0.48428145 -1.312163 0.11731844 0.18276013 1.0 3621 tags=48%, list=24%, signal=63% NCRNA TRANSCRIPTION%GOBP%GO:0098781 NCRNA TRANSCRIPTION%GOBP%GO:0098781 80 -0.38014504 -1.3105476 0.04347826 0.184325 1.0 3383 tags=36%, list=22%, signal=46% ATM PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ATM PATHWAY ATM PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ATM PATHWAY 34 -0.4584039 -1.3101863 0.10248447 0.18454966 1.0 2455 tags=29%, list=16%, signal=35% THIOESTER METABOLIC PROCESS%GOBP%GO:0035383 THIOESTER METABOLIC PROCESS%GOBP%GO:0035383 59 -0.40185562 -1.3101336 0.058035713 0.18444787 1.0 1796 tags=22%, list=12%, signal=25% REGULATION OF NIK/NF-KAPPAB SIGNALING%GOBP%GO:1901222 REGULATION OF NIK/NF-KAPPAB SIGNALING%GOBP%GO:1901222 40 -0.43959472 -1.3094056 0.10091743 0.18501452 1.0 2124 tags=20%, list=14%, signal=23% BUDDING AND MATURATION OF HIV VIRION%REACTOME%R-HSA-162588.1 BUDDING AND MATURATION OF HIV VIRION%REACTOME%R-HSA-162588.1 25 -0.48790714 -1.3092625 0.109792285 0.18500158 1.0 4440 tags=48%, list=29%, signal=68% CARBOXYLIC ACID CATABOLIC PROCESS%GOBP%GO:0046395 CARBOXYLIC ACID CATABOLIC PROCESS%GOBP%GO:0046395 175 -0.33433223 -1.3082545 0.021505376 0.18589169 1.0 3829 tags=41%, list=25%, signal=54% MALE GAMETE GENERATION%GOBP%GO:0048232 MALE GAMETE GENERATION%GOBP%GO:0048232 119 -0.35775617 -1.3077769 0.01910828 0.18624197 1.0 2583 tags=25%, list=17%, signal=30% CENTRIOLE ASSEMBLY%GOBP%GO:0098534 CENTRIOLE ASSEMBLY%GOBP%GO:0098534 19 -0.51545405 -1.3063966 0.14363144 0.18756735 1.0 4640 tags=53%, list=31%, signal=76% PROTEIN ACETYLATION%GOBP%GO:0006473 PROTEIN ACETYLATION%GOBP%GO:0006473 81 -0.37884307 -1.3061247 0.049261082 0.18770723 1.0 4401 tags=38%, list=29%, signal=54% THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 60%2514856 THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 60%2514856 20 -0.51829636 -1.3060733 0.13333334 0.1875981 1.0 754 tags=15%, list=5%, signal=16% BIOCARTA_IL10_PATHWAY%MSIGDB_C2%BIOCARTA_IL10_PATHWAY BIOCARTA_IL10_PATHWAY%MSIGDB_C2%BIOCARTA_IL10_PATHWAY 16 -0.55793786 -1.305452 0.14354067 0.18814974 1.0 2956 tags=44%, list=19%, signal=54% APOPTOSIS SIGNALING PATHWAY%PANTHER PATHWAY%P00006 APOPTOSIS SIGNALING PATHWAY%PANTHER PATHWAY%P00006 104 -0.36525282 -1.3051903 0.019736841 0.18824923 1.0 3621 tags=34%, list=24%, signal=44% PID_FOXO_PATHWAY%MSIGDB_C2%PID_FOXO_PATHWAY PID_FOXO_PATHWAY%MSIGDB_C2%PID_FOXO_PATHWAY 48 -0.41358888 -1.3043932 0.09727626 0.18896398 1.0 2178 tags=23%, list=14%, signal=27% DNA CATABOLIC PROCESS, ENDONUCLEOLYTIC%GOBP%GO:0000737 DNA CATABOLIC PROCESS, ENDONUCLEOLYTIC%GOBP%GO:0000737 15 -0.5599166 -1.3035933 0.16581632 0.18971401 1.0 4892 tags=60%, list=32%, signal=88% ACYL-COA METABOLIC PROCESS%GOBP%GO:0006637 ACYL-COA METABOLIC PROCESS%GOBP%GO:0006637 59 -0.40185562 -1.3033419 0.07053942 0.18983825 1.0 1796 tags=22%, list=12%, signal=25% CELLULAR AMINO ACID CATABOLIC PROCESS%GOBP%GO:0009063 CELLULAR AMINO ACID CATABOLIC PROCESS%GOBP%GO:0009063 82 -0.37960476 -1.3031873 0.049261082 0.18985483 1.0 3921 tags=41%, list=26%, signal=56% CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:0044839 CELL CYCLE G2/M PHASE TRANSITION%GOBP%GO:0044839 120 -0.35635257 -1.302585 0.027586207 0.19035506 1.0 2430 tags=26%, list=16%, signal=31% TNFR1-INDUCED NFKAPPAB SIGNALING PATHWAY%REACTOME DATABASE ID RELEASE 60%5357956 TNFR1-INDUCED NFKAPPAB SIGNALING PATHWAY%REACTOME DATABASE ID RELEASE 60%5357956 26 -0.4808333 -1.3024279 0.13128492 0.19036019 1.0 1913 tags=19%, list=13%, signal=22% TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES%REACTOME DATABASE ID RELEASE 60%6791312 TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES%REACTOME DATABASE ID RELEASE 60%6791312 47 -0.42358527 -1.3018413 0.08627451 0.1907899 1.0 3079 tags=36%, list=20%, signal=45% DSRNA FRAGMENTATION%GOBP%GO:0031050 DSRNA FRAGMENTATION%GOBP%GO:0031050 18 -0.53204656 -1.3012314 0.13972603 0.19124061 1.0 2940 tags=39%, list=19%, signal=48% REGULATION OF TRANSLATION IN RESPONSE TO STRESS%GOBP%GO:0043555 REGULATION OF TRANSLATION IN RESPONSE TO STRESS%GOBP%GO:0043555 16 -0.51696354 -1.3001008 0.12919897 0.19223626 1.0 3002 tags=38%, list=20%, signal=47% REGULATION OF DNA REPAIR%GOBP%GO:0006282 REGULATION OF DNA REPAIR%GOBP%GO:0006282 73 -0.38678527 -1.2971927 0.055837564 0.19525848 1.0 2772 tags=29%, list=18%, signal=35% BUTYRATE RESPONSE FACTOR 1 (BRF1) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450385.2 BUTYRATE RESPONSE FACTOR 1 (BRF1) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450385.2 17 -0.54160404 -1.2971376 0.1509901 0.19514343 1.0 1022 tags=24%, list=7%, signal=25% POSITIVE REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0050434 POSITIVE REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0050434 35 -0.45611334 -1.2964422 0.15436241 0.1957234 1.0 3095 tags=37%, list=20%, signal=47% NECROTIC CELL DEATH%GOBP%GO:0070265 NECROTIC CELL DEATH%GOBP%GO:0070265 20 -0.51115316 -1.2957712 0.14477211 0.1962902 1.0 2314 tags=25%, list=15%, signal=29% TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS%REACTOME%R-HSA-5669034.2 TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS%REACTOME%R-HSA-5669034.2 26 -0.47250172 -1.2956629 0.12765957 0.1962671 1.0 1097 tags=27%, list=7%, signal=29% HISTONE MONOUBIQUITINATION%GOBP%GO:0010390 HISTONE MONOUBIQUITINATION%GOBP%GO:0010390 22 -0.49351236 -1.2951777 0.14099216 0.19664824 1.0 2054 tags=14%, list=14%, signal=16% TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES%REACTOME DATABASE ID RELEASE 60%6796648 TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES%REACTOME DATABASE ID RELEASE 60%6796648 56 -0.4049234 -1.2949764 0.07116105 0.19669951 1.0 4719 tags=45%, list=31%, signal=64% REGULATION OF TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0034243 REGULATION OF TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0034243 19 -0.51131535 -1.2936774 0.13736264 0.19799045 1.0 3792 tags=32%, list=25%, signal=42% NEGATIVE REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903051 NEGATIVE REGULATION OF PROTEOLYSIS INVOLVED IN CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903051 28 -0.4691919 -1.2924383 0.119760476 0.19918075 1.0 3974 tags=39%, list=26%, signal=53% PURINE-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0072522 PURINE-CONTAINING COMPOUND BIOSYNTHETIC PROCESS%GOBP%GO:0072522 90 -0.3658477 -1.2919081 0.031746034 0.1996609 1.0 2721 tags=37%, list=18%, signal=44% FATTY ACID METABOLISM%REACTOME DATABASE ID RELEASE 60%8978868 FATTY ACID METABOLISM%REACTOME DATABASE ID RELEASE 60%8978868 143 -0.33932808 -1.2914702 0.033613447 0.19998568 1.0 3690 tags=33%, list=24%, signal=43% CILIARY BASAL BODY DOCKING%GOBP%GO:0097711 CILIARY BASAL BODY DOCKING%GOBP%GO:0097711 86 -0.37199962 -1.2911187 0.05263158 0.20021315 1.0 4707 tags=42%, list=31%, signal=60% SUMO E3 LIGASES SUMOYLATE TARGET PROTEINS%REACTOME DATABASE ID RELEASE 60%3108232 SUMO E3 LIGASES SUMOYLATE TARGET PROTEINS%REACTOME DATABASE ID RELEASE 60%3108232 108 -0.35353228 -1.2905996 0.04733728 0.20064634 1.0 4339 tags=40%, list=29%, signal=55% DNA DAMAGE CHECKPOINT%GOBP%GO:0000077 DNA DAMAGE CHECKPOINT%GOBP%GO:0000077 122 -0.35593566 -1.2890319 0.07189543 0.20210788 1.0 4450 tags=43%, list=29%, signal=61% REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0006356 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0006356 28 -0.46294603 -1.2890184 0.1183432 0.2019492 1.0 2682 tags=32%, list=18%, signal=39% REGULATION OF TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0060260 REGULATION OF TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0060260 21 -0.5092744 -1.2889432 0.15041783 0.20184304 1.0 3181 tags=38%, list=21%, signal=48% MEIOTIC CELL CYCLE%GOBP%GO:0051321 MEIOTIC CELL CYCLE%GOBP%GO:0051321 75 -0.37653938 -1.2884805 0.06866953 0.20216683 1.0 4993 tags=56%, list=33%, signal=83% CYTOKINE SECRETION%GOBP%GO:0050663 CYTOKINE SECRETION%GOBP%GO:0050663 23 -0.48695454 -1.2883687 0.14971751 0.20213602 1.0 849 tags=26%, list=6%, signal=28% POSITIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903557 POSITIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903557 34 -0.4290407 -1.288142 0.14527027 0.20225158 1.0 2196 tags=35%, list=14%, signal=41% BIOCARTA_TNFR2_PATHWAY%MSIGDB_C2%BIOCARTA_TNFR2_PATHWAY BIOCARTA_TNFR2_PATHWAY%MSIGDB_C2%BIOCARTA_TNFR2_PATHWAY 17 -0.5363138 -1.2856376 0.15608466 0.20506573 1.0 1888 tags=29%, list=12%, signal=34% REGULATION OF GENE SILENCING BY RNA%GOBP%GO:0060966 REGULATION OF GENE SILENCING BY RNA%GOBP%GO:0060966 82 -0.3738782 -1.2853928 0.07058824 0.20516406 1.0 4337 tags=44%, list=29%, signal=61% ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON%REACTOME%R-HSA-936964.2 ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON%REACTOME%R-HSA-936964.2 17 -0.5413753 -1.2843634 0.15776698 0.20618534 1.0 4736 tags=53%, list=31%, signal=77% NUCLEOTIDE-EXCISION REPAIR, DNA INCISION, 3'-TO LESION%GOBP%GO:0006295 NUCLEOTIDE-EXCISION REPAIR, DNA INCISION, 3'-TO LESION%GOBP%GO:0006295 21 -0.48400265 -1.2837114 0.13352273 0.20677657 1.0 4550 tags=52%, list=30%, signal=75% HALLMARK_INFLAMMATORY_RESPONSE%MSIGDB_C2%HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE%MSIGDB_C2%HALLMARK_INFLAMMATORY_RESPONSE 183 -0.33065024 -1.283138 0.0 0.20727119 1.0 1387 tags=20%, list=9%, signal=22% POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904358 POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904358 34 -0.44495553 -1.2826661 0.13455658 0.20758373 1.0 5259 tags=56%, list=35%, signal=85% POSITIVE REGULATION OF CHROMOSOME ORGANIZATION%GOBP%GO:2001252 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION%GOBP%GO:2001252 122 -0.35440248 -1.2814732 0.014705882 0.20878395 1.0 4631 tags=39%, list=30%, signal=55% PROTEIN ACYLATION%GOBP%GO:0043543 PROTEIN ACYLATION%GOBP%GO:0043543 107 -0.35971317 -1.2804381 0.049382716 0.20975113 1.0 2861 tags=24%, list=19%, signal=30% HISTIDINE, LYSINE, PHENYLALANINE, TYROSINE, PROLINE AND TRYPTOPHAN CATABOLISM%REACTOME DATABASE ID RELEASE 60%6788656 HISTIDINE, LYSINE, PHENYLALANINE, TYROSINE, PROLINE AND TRYPTOPHAN CATABOLISM%REACTOME DATABASE ID RELEASE 60%6788656 34 -0.4388322 -1.2800245 0.114754096 0.21004225 1.0 2813 tags=29%, list=18%, signal=36% PHOSPHATIDYLETHANOLAMINE ACYL-CHAIN REMODELING%GOBP%GO:0036152 PHOSPHATIDYLETHANOLAMINE ACYL-CHAIN REMODELING%GOBP%GO:0036152 19 -0.5027368 -1.2789974 0.16976127 0.21108502 1.0 1768 tags=37%, list=12%, signal=42% PEROXISOMAL LIPID METABOLISM%REACTOME DATABASE ID RELEASE 60%390918 PEROXISOMAL LIPID METABOLISM%REACTOME DATABASE ID RELEASE 60%390918 23 -0.4776911 -1.2787344 0.16056338 0.21120603 1.0 4817 tags=52%, list=32%, signal=76% REGULATION OF INTERLEUKIN-10 PRODUCTION%GOBP%GO:0032653 REGULATION OF INTERLEUKIN-10 PRODUCTION%GOBP%GO:0032653 26 -0.48488197 -1.2783535 0.1402439 0.21142797 1.0 2864 tags=50%, list=19%, signal=61% GENE SILENCING BY RNA%GOBP%GO:0031047 GENE SILENCING BY RNA%GOBP%GO:0031047 39 -0.4296312 -1.2774245 0.115625 0.21230209 1.0 2940 tags=31%, list=19%, signal=38% ORGANIC ACID CATABOLIC PROCESS%GOBP%GO:0016054 ORGANIC ACID CATABOLIC PROCESS%GOBP%GO:0016054 175 -0.33433223 -1.2758905 0.030927835 0.21387112 1.0 3829 tags=41%, list=25%, signal=54% CENTRIOLE REPLICATION%GOBP%GO:0007099 CENTRIOLE REPLICATION%GOBP%GO:0007099 15 -0.530484 -1.2751966 0.15724815 0.21449246 1.0 3749 tags=47%, list=25%, signal=62% TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES%REACTOME DATABASE ID RELEASE 60%5633008 TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES%REACTOME DATABASE ID RELEASE 60%5633008 43 -0.423317 -1.274347 0.09893993 0.21533918 1.0 2227 tags=23%, list=15%, signal=27% LYMPHOCYTE PROLIFERATION%GOBP%GO:0046651 LYMPHOCYTE PROLIFERATION%GOBP%GO:0046651 24 -0.48156577 -1.2742733 0.16285715 0.21523198 1.0 3986 tags=50%, list=26%, signal=68% G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000086 G2/M TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:0000086 118 -0.35828036 -1.2728932 0.036809817 0.21669976 1.0 2430 tags=26%, list=16%, signal=31% REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING%GOBP%GO:0060147 REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING%GOBP%GO:0060147 82 -0.3738782 -1.272812 0.06626506 0.21660921 1.0 4337 tags=44%, list=29%, signal=61% POSITIVE REGULATION OF PEPTIDASE ACTIVITY%GOBP%GO:0010952 POSITIVE REGULATION OF PEPTIDASE ACTIVITY%GOBP%GO:0010952 110 -0.3573521 -1.2699983 0.04761905 0.21985741 1.0 1315 tags=18%, list=9%, signal=20% CELLULAR COMPONENT DISASSEMBLY INVOLVED IN EXECUTION PHASE OF APOPTOSIS%GOBP%GO:0006921 CELLULAR COMPONENT DISASSEMBLY INVOLVED IN EXECUTION PHASE OF APOPTOSIS%GOBP%GO:0006921 22 -0.4923361 -1.2698491 0.1530343 0.21983245 1.0 2881 tags=32%, list=19%, signal=39% SPERMATOGENESIS%GOBP%GO:0007283 SPERMATOGENESIS%GOBP%GO:0007283 114 -0.35178572 -1.2698327 0.027210884 0.21967201 1.0 2583 tags=25%, list=17%, signal=30% MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032943 MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032943 25 -0.47517326 -1.2695143 0.14619882 0.21981367 1.0 3986 tags=48%, list=26%, signal=65% MEMBRANE FUSION%GOBP%GO:0061025 MEMBRANE FUSION%GOBP%GO:0061025 126 -0.34150514 -1.2693139 0.030534351 0.21987358 1.0 3382 tags=29%, list=22%, signal=36% MEIOTIC NUCLEAR DIVISION%GOBP%GO:0140013 MEIOTIC NUCLEAR DIVISION%GOBP%GO:0140013 61 -0.3855666 -1.2692273 0.07024793 0.2197911 1.0 3064 tags=36%, list=20%, signal=45% POSITIVE REGULATION OF MITOTIC CELL CYCLE PHASE TRANSITION%GOBP%GO:1901992 POSITIVE REGULATION OF MITOTIC CELL CYCLE PHASE TRANSITION%GOBP%GO:1901992 37 -0.43875784 -1.267963 0.13621262 0.22112377 1.0 2435 tags=35%, list=16%, signal=42% POSITIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0090200 POSITIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0090200 23 -0.48564395 -1.2679485 0.15223098 0.22095679 1.0 4371 tags=52%, list=29%, signal=73% BRANCHED-CHAIN AMINO ACID CATABOLISM%REACTOME DATABASE ID RELEASE 60%70895 BRANCHED-CHAIN AMINO ACID CATABOLISM%REACTOME DATABASE ID RELEASE 60%70895 23 -0.48269004 -1.2677668 0.14366198 0.22098014 1.0 3747 tags=48%, list=25%, signal=63% HALLMARK_SPERMATOGENESIS%MSIGDB_C2%HALLMARK_SPERMATOGENESIS HALLMARK_SPERMATOGENESIS%MSIGDB_C2%HALLMARK_SPERMATOGENESIS 90 -0.36115867 -1.2674184 0.074285716 0.22118346 1.0 1809 tags=24%, list=12%, signal=28% NEGATIVE REGULATION OF LYMPHOCYTE ACTIVATION%GOBP%GO:0051250 NEGATIVE REGULATION OF LYMPHOCYTE ACTIVATION%GOBP%GO:0051250 61 -0.3871553 -1.2668368 0.06910569 0.22164784 1.0 2135 tags=38%, list=14%, signal=44% FAS%IOB%FAS FAS%IOB%FAS 113 -0.3534798 -1.2664689 0.094936706 0.22191511 1.0 2585 tags=23%, list=17%, signal=28% POSITIVE REGULATION OF TELOMERE CAPPING%GOBP%GO:1904355 POSITIVE REGULATION OF TELOMERE CAPPING%GOBP%GO:1904355 16 -0.5340428 -1.2662427 0.16363636 0.22198644 1.0 2664 tags=31%, list=18%, signal=38% REGULATION OF PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:1903214 REGULATION OF PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:1903214 78 -0.37254053 -1.265418 0.08121827 0.22274943 1.0 3190 tags=29%, list=21%, signal=37% SUMOYLATION%REACTOME%R-HSA-2990846.2 SUMOYLATION%REACTOME%R-HSA-2990846.2 114 -0.3526383 -1.2654014 0.050632913 0.22257452 1.0 4339 tags=39%, list=29%, signal=54% ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE%REACTOME%R-HSA-5620912.2 ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE%REACTOME%R-HSA-5620912.2 86 -0.36638516 -1.2650572 0.075675674 0.22278377 1.0 4707 tags=42%, list=31%, signal=60% THE ROLE OF NEF IN HIV-1 REPLICATION AND DISEASE PATHOGENESIS%REACTOME%R-HSA-164952.1 THE ROLE OF NEF IN HIV-1 REPLICATION AND DISEASE PATHOGENESIS%REACTOME%R-HSA-164952.1 27 -0.46215123 -1.2649341 0.1529052 0.2227442 1.0 2510 tags=22%, list=17%, signal=27% POSITIVE REGULATION OF MEMBRANE PERMEABILITY%GOBP%GO:1905710 POSITIVE REGULATION OF MEMBRANE PERMEABILITY%GOBP%GO:1905710 15 -0.53115165 -1.2646718 0.15815085 0.2228476 1.0 2067 tags=27%, list=14%, signal=31% POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION%GOBP%GO:0010822 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION%GOBP%GO:0010822 139 -0.3378932 -1.264227 0.04477612 0.22318019 1.0 3345 tags=29%, list=22%, signal=37% PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE%GOBP%GO:0002440 PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE%GOBP%GO:0002440 29 -0.4542586 -1.2630095 0.14583333 0.22439748 1.0 3863 tags=48%, list=25%, signal=65% BRANCHED-CHAIN AMINO ACID CATABOLIC PROCESS%GOBP%GO:0009083 BRANCHED-CHAIN AMINO ACID CATABOLIC PROCESS%GOBP%GO:0009083 20 -0.5004839 -1.2615093 0.16802168 0.22603473 1.0 3747 tags=55%, list=25%, signal=73% POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0045943 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER%GOBP%GO:0045943 20 -0.4930102 -1.2610556 0.15895954 0.22639036 1.0 2624 tags=25%, list=17%, signal=30% INTERNAL PROTEIN AMINO ACID ACETYLATION%GOBP%GO:0006475 INTERNAL PROTEIN AMINO ACID ACETYLATION%GOBP%GO:0006475 68 -0.3791835 -1.260483 0.085365854 0.22688879 1.0 4265 tags=37%, list=28%, signal=51% MRNA DECAY BY 3' TO 5' EXORIBONUCLEASE%REACTOME DATABASE ID RELEASE 60%429958 MRNA DECAY BY 3' TO 5' EXORIBONUCLEASE%REACTOME DATABASE ID RELEASE 60%429958 15 -0.5503534 -1.2596242 0.17902814 0.22771984 1.0 3080 tags=47%, list=20%, signal=58% MISFOLDED OR INCOMPLETELY SYNTHESIZED PROTEIN CATABOLIC PROCESS%GOBP%GO:0006515 MISFOLDED OR INCOMPLETELY SYNTHESIZED PROTEIN CATABOLIC PROCESS%GOBP%GO:0006515 22 -0.49221492 -1.2596184 0.16320474 0.22753343 1.0 4315 tags=41%, list=28%, signal=57% POSITIVE REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045070 POSITIVE REGULATION OF VIRAL GENOME REPLICATION%GOBP%GO:0045070 27 -0.4529786 -1.2587862 0.15047021 0.22837399 1.0 3213 tags=41%, list=21%, signal=52% DENDRITIC CELL CHEMOTAXIS%GOBP%GO:0002407 DENDRITIC CELL CHEMOTAXIS%GOBP%GO:0002407 15 -0.529345 -1.2576302 0.16584158 0.22955635 1.0 1894 tags=27%, list=12%, signal=30% MONOSACCHARIDE METABOLIC PROCESS%GOBP%GO:0005996 MONOSACCHARIDE METABOLIC PROCESS%GOBP%GO:0005996 112 -0.34896994 -1.257258 0.044585988 0.22981924 1.0 3803 tags=37%, list=25%, signal=48% RNA POLYMERASE I TRANSCRIPTION%REACTOME DATABASE ID RELEASE 60%73864 RNA POLYMERASE I TRANSCRIPTION%REACTOME DATABASE ID RELEASE 60%73864 82 -0.36684722 -1.2565123 0.07486631 0.2305323 1.0 3782 tags=40%, list=25%, signal=53% LEUKOCYTE HOMEOSTASIS%GOBP%GO:0001776 LEUKOCYTE HOMEOSTASIS%GOBP%GO:0001776 21 -0.4924897 -1.255631 0.14814815 0.23146163 1.0 2135 tags=24%, list=14%, signal=28% REGULATION OF OXIDATIVE STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902175 REGULATION OF OXIDATIVE STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902175 23 -0.47138485 -1.254712 0.16207951 0.23236275 1.0 4729 tags=48%, list=31%, signal=69% VIRAL BUDDING%GOBP%GO:0046755 VIRAL BUDDING%GOBP%GO:0046755 22 -0.4759142 -1.2543194 0.1878453 0.23266536 1.0 4244 tags=41%, list=28%, signal=57% GLYCOSYL COMPOUND CATABOLIC PROCESS%GOBP%GO:1901658 GLYCOSYL COMPOUND CATABOLIC PROCESS%GOBP%GO:1901658 25 -0.45714197 -1.254132 0.14713897 0.23272946 1.0 2354 tags=36%, list=15%, signal=43% REGULATION OF T-HELPER CELL DIFFERENTIATION%GOBP%GO:0045622 REGULATION OF T-HELPER CELL DIFFERENTIATION%GOBP%GO:0045622 19 -0.49778298 -1.2536279 0.18434343 0.2331011 1.0 2140 tags=37%, list=14%, signal=43% TSH%NETPATH%TSH TSH%NETPATH%TSH 79 -0.3616854 -1.2506943 0.08 0.23651977 1.0 1739 tags=19%, list=11%, signal=21% FAS (CD95) SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FAS (CD95) SIGNALING PATHWAY FAS (CD95) SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FAS (CD95) SIGNALING PATHWAY 35 -0.42438486 -1.2498192 0.123839006 0.23742838 1.0 2167 tags=26%, list=14%, signal=30% POSTTRANSCRIPTIONAL GENE SILENCING%GOBP%GO:0016441 POSTTRANSCRIPTIONAL GENE SILENCING%GOBP%GO:0016441 38 -0.42253834 -1.2493813 0.12772585 0.23776373 1.0 2940 tags=32%, list=19%, signal=39% SPINDLE LOCALIZATION%GOBP%GO:0051653 SPINDLE LOCALIZATION%GOBP%GO:0051653 22 -0.48579773 -1.2491475 0.15159574 0.23784895 1.0 2256 tags=32%, list=15%, signal=37% MITOCHONDRIAL GENOME MAINTENANCE%GOBP%GO:0000002 MITOCHONDRIAL GENOME MAINTENANCE%GOBP%GO:0000002 15 -0.5370148 -1.2472305 0.19201995 0.24015231 1.0 1981 tags=33%, list=13%, signal=38% CYTOKINE PRODUCTION%GOBP%GO:0001816 CYTOKINE PRODUCTION%GOBP%GO:0001816 56 -0.39376208 -1.2472206 0.09638554 0.23996288 1.0 254 tags=14%, list=2%, signal=14% POSITIVE REGULATION OF RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:1905898 POSITIVE REGULATION OF RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:1905898 26 -0.46517166 -1.2468988 0.16384181 0.24017869 1.0 2208 tags=31%, list=15%, signal=36% NEGATIVE REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032945 NEGATIVE REGULATION OF MONONUCLEAR CELL PROLIFERATION%GOBP%GO:0032945 30 -0.43878946 -1.2464986 0.16510904 0.24053106 1.0 2135 tags=37%, list=14%, signal=43% REGULATION OF GENE SILENCING BY MIRNA%GOBP%GO:0060964 REGULATION OF GENE SILENCING BY MIRNA%GOBP%GO:0060964 80 -0.36498225 -1.2463828 0.06763285 0.24047863 1.0 4337 tags=43%, list=29%, signal=59% BIOCARTA_ACTINY_PATHWAY%MSIGDB_C2%BIOCARTA_ACTINY_PATHWAY BIOCARTA_ACTINY_PATHWAY%MSIGDB_C2%BIOCARTA_ACTINY_PATHWAY 18 -0.5047206 -1.2462548 0.1641791 0.24045277 1.0 2623 tags=28%, list=17%, signal=34% BIOCARTA_ATM_PATHWAY%MSIGDB_C2%BIOCARTA_ATM_PATHWAY BIOCARTA_ATM_PATHWAY%MSIGDB_C2%BIOCARTA_ATM_PATHWAY 20 -0.48442835 -1.2454764 0.14550264 0.24120043 1.0 1054 tags=30%, list=7%, signal=32% POSITIVE REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:2000516 POSITIVE REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:2000516 20 -0.4807221 -1.2448448 0.1820449 0.2418492 1.0 2140 tags=45%, list=14%, signal=52% METABOLISM OF STEROID HORMONES%REACTOME%R-HSA-196071.2 METABOLISM OF STEROID HORMONES%REACTOME%R-HSA-196071.2 22 -0.48564312 -1.2437143 0.15877438 0.24309118 1.0 4722 tags=36%, list=31%, signal=53% CARBOHYDRATE DERIVATIVE TRANSPORT%GOBP%GO:1901264 CARBOHYDRATE DERIVATIVE TRANSPORT%GOBP%GO:1901264 29 -0.44144568 -1.2413301 0.14670658 0.24585824 1.0 5315 tags=48%, list=35%, signal=74% DNA DOUBLE-STRAND BREAK PROCESSING%GOBP%GO:0000729 DNA DOUBLE-STRAND BREAK PROCESSING%GOBP%GO:0000729 17 -0.5175845 -1.2411623 0.1868421 0.2458762 1.0 4719 tags=53%, list=31%, signal=77% CELLULAR RESPONSE TO AMINO ACID STARVATION%GOBP%GO:0034198 CELLULAR RESPONSE TO AMINO ACID STARVATION%GOBP%GO:0034198 37 -0.41903323 -1.240942 0.14583333 0.24595854 1.0 2487 tags=22%, list=16%, signal=26% ORGANELLE FUSION%GOBP%GO:0048284 ORGANELLE FUSION%GOBP%GO:0048284 113 -0.34405622 -1.2407992 0.07189543 0.24595974 1.0 3780 tags=32%, list=25%, signal=42% REGULATION OF CYTOKINESIS%GOBP%GO:0032465 REGULATION OF CYTOKINESIS%GOBP%GO:0032465 47 -0.39813513 -1.2390994 0.13186814 0.24798103 1.0 4083 tags=40%, list=27%, signal=55% MITOTIC CELL CYCLE CHECKPOINT%GOBP%GO:0007093 MITOTIC CELL CYCLE CHECKPOINT%GOBP%GO:0007093 123 -0.343864 -1.239012 0.10273973 0.24789198 1.0 4450 tags=43%, list=29%, signal=60% PID_FAS_PATHWAY%MSIGDB_C2%PID_FAS_PATHWAY PID_FAS_PATHWAY%MSIGDB_C2%PID_FAS_PATHWAY 38 -0.4156452 -1.2387571 0.15333334 0.2480665 1.0 3240 tags=32%, list=21%, signal=40% POSITIVE REGULATION OF ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046635 POSITIVE REGULATION OF ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046635 30 -0.4345351 -1.2384763 0.16246499 0.24820705 1.0 2167 tags=47%, list=14%, signal=54% TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002224 TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002224 84 -0.35205913 -1.2377882 0.085427135 0.24887675 1.0 3626 tags=36%, list=24%, signal=47% NUCLEOTIDE-EXCISION REPAIR, PREINCISION COMPLEX STABILIZATION%GOBP%GO:0006293 NUCLEOTIDE-EXCISION REPAIR, PREINCISION COMPLEX STABILIZATION%GOBP%GO:0006293 21 -0.48400265 -1.2369605 0.18867925 0.24970877 1.0 4550 tags=52%, list=30%, signal=75% DENDRITIC CELL MIGRATION%GOBP%GO:0036336 DENDRITIC CELL MIGRATION%GOBP%GO:0036336 16 -0.5130909 -1.2364532 0.21116506 0.2501487 1.0 1894 tags=25%, list=12%, signal=29% ANTEROGRADE AXONAL TRANSPORT%GOBP%GO:0008089 ANTEROGRADE AXONAL TRANSPORT%GOBP%GO:0008089 20 -0.47600654 -1.2361567 0.16949153 0.2503199 1.0 3049 tags=30%, list=20%, signal=37% MEIOTIC CELL CYCLE PROCESS%GOBP%GO:1903046 MEIOTIC CELL CYCLE PROCESS%GOBP%GO:1903046 67 -0.3730792 -1.2359574 0.11415525 0.25037467 1.0 3438 tags=37%, list=23%, signal=48% BIOCARTA_CELLCYCLE_PATHWAY%MSIGDB_C2%BIOCARTA_CELLCYCLE_PATHWAY BIOCARTA_CELLCYCLE_PATHWAY%MSIGDB_C2%BIOCARTA_CELLCYCLE_PATHWAY 23 -0.4648373 -1.2358729 0.18803419 0.25028208 1.0 1739 tags=43%, list=11%, signal=49% HEXOSE METABOLIC PROCESS%GOBP%GO:0019318 HEXOSE METABOLIC PROCESS%GOBP%GO:0019318 91 -0.35096613 -1.2350978 0.0875 0.25105032 1.0 3683 tags=33%, list=24%, signal=43% PID_IL1_PATHWAY%MSIGDB_C2%PID_IL1_PATHWAY PID_IL1_PATHWAY%MSIGDB_C2%PID_IL1_PATHWAY 33 -0.42509654 -1.2342981 0.16764706 0.25189573 1.0 3183 tags=30%, list=21%, signal=38% SECONDARY ALCOHOL BIOSYNTHETIC PROCESS%GOBP%GO:1902653 SECONDARY ALCOHOL BIOSYNTHETIC PROCESS%GOBP%GO:1902653 31 -0.438696 -1.2342738 0.18241042 0.25173935 1.0 1994 tags=26%, list=13%, signal=30% NEGATIVE REGULATION OF NF-KAPPAB TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0032088 NEGATIVE REGULATION OF NF-KAPPAB TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0032088 52 -0.3895892 -1.2333065 0.12863071 0.2528253 1.0 3154 tags=42%, list=21%, signal=53% INITIAL TRIGGERING OF COMPLEMENT%REACTOME DATABASE ID RELEASE 60%166663 INITIAL TRIGGERING OF COMPLEMENT%REACTOME DATABASE ID RELEASE 60%166663 15 -0.5223743 -1.2322698 0.20906802 0.25398543 1.0 1723 tags=40%, list=11%, signal=45% ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046631 ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0046631 24 -0.45894146 -1.2313305 0.18072289 0.25504154 1.0 2606 tags=42%, list=17%, signal=50% IL6-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL6-MEDIATED SIGNALING EVENTS IL6-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL6-MEDIATED SIGNALING EVENTS 43 -0.4015592 -1.2307513 0.1384083 0.25561407 1.0 294 tags=9%, list=2%, signal=9% RNA SECONDARY STRUCTURE UNWINDING%GOBP%GO:0010501 RNA SECONDARY STRUCTURE UNWINDING%GOBP%GO:0010501 35 -0.4154616 -1.2293301 0.15974441 0.25720927 1.0 2896 tags=26%, list=19%, signal=32% REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032210 REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032210 49 -0.38863626 -1.2292984 0.12589929 0.25703707 1.0 3588 tags=35%, list=24%, signal=45% REGULATION OF FATTY ACID BIOSYNTHETIC PROCESS%GOBP%GO:0042304 REGULATION OF FATTY ACID BIOSYNTHETIC PROCESS%GOBP%GO:0042304 27 -0.4521378 -1.2291601 0.17777778 0.25700742 1.0 1132 tags=22%, list=7%, signal=24% NUCLEOSIDE PHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:1901293 NUCLEOSIDE PHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:1901293 115 -0.33394986 -1.2289568 0.08496732 0.25707304 1.0 2767 tags=36%, list=18%, signal=43% REGULATION OF DEFENSE RESPONSE TO VIRUS BY VIRUS%GOBP%GO:0050690 REGULATION OF DEFENSE RESPONSE TO VIRUS BY VIRUS%GOBP%GO:0050690 28 -0.44424337 -1.228399 0.16119403 0.25762278 1.0 2510 tags=25%, list=17%, signal=30% ACTIVATION OF HOX GENES DURING DIFFERENTIATION%REACTOME DATABASE ID RELEASE 60%5619507 ACTIVATION OF HOX GENES DURING DIFFERENTIATION%REACTOME DATABASE ID RELEASE 60%5619507 88 -0.35197395 -1.228291 0.103626944 0.25756505 1.0 3326 tags=35%, list=22%, signal=45% REGULATION OF TP53 DEGRADATION%REACTOME DATABASE ID RELEASE 60%6804757 REGULATION OF TP53 DEGRADATION%REACTOME DATABASE ID RELEASE 60%6804757 36 -0.41606972 -1.2276708 0.17307693 0.25812772 1.0 2803 tags=22%, list=18%, signal=27% POSITIVE REGULATION OF SEQUENCE-SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0051091 POSITIVE REGULATION OF SEQUENCE-SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY%GOBP%GO:0051091 175 -0.31468195 -1.2267227 0.06542056 0.2591492 1.0 2570 tags=23%, list=17%, signal=28% NEGATIVE REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050672 NEGATIVE REGULATION OF LYMPHOCYTE PROLIFERATION%GOBP%GO:0050672 30 -0.43878946 -1.2255188 0.19308357 0.26056468 1.0 2135 tags=37%, list=14%, signal=43% IFN-ALPHA%IOB%IFN-ALPHA IFN-ALPHA%IOB%IFN-ALPHA 37 -0.41088003 -1.2254629 0.14723927 0.26043633 1.0 2609 tags=32%, list=17%, signal=39% CHOLESTEROL BIOSYNTHETIC PROCESS%GOBP%GO:0006695 CHOLESTEROL BIOSYNTHETIC PROCESS%GOBP%GO:0006695 30 -0.44336447 -1.2235031 0.17058824 0.2628715 1.0 1994 tags=27%, list=13%, signal=31% INFLAMMASOMES%REACTOME DATABASE ID RELEASE 60%622312 INFLAMMASOMES%REACTOME DATABASE ID RELEASE 60%622312 19 -0.49747592 -1.22312 0.21010639 0.26315486 1.0 4410 tags=53%, list=29%, signal=74% HDACS DEACETYLATE HISTONES%REACTOME%R-HSA-3214815.2 HDACS DEACETYLATE HISTONES%REACTOME%R-HSA-3214815.2 60 -0.37310755 -1.2229655 0.10638298 0.2631436 1.0 4044 tags=40%, list=27%, signal=54% MACROMOLECULE METHYLATION%GOBP%GO:0043414 MACROMOLECULE METHYLATION%GOBP%GO:0043414 106 -0.3439405 -1.2227173 0.103896104 0.2632611 1.0 4752 tags=37%, list=31%, signal=53% RESPONSE TO TOXIC SUBSTANCE%GOBP%GO:0009636 RESPONSE TO TOXIC SUBSTANCE%GOBP%GO:0009636 42 -0.40395796 -1.2226399 0.13953489 0.26313448 1.0 3841 tags=29%, list=25%, signal=38% SPINDLE ASSEMBLY CHECKPOINT%GOBP%GO:0071173 SPINDLE ASSEMBLY CHECKPOINT%GOBP%GO:0071173 15 -0.51399225 -1.2206228 0.21052632 0.26568422 1.0 4895 tags=73%, list=32%, signal=108% REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:2000514 REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:2000514 28 -0.4409702 -1.22013 0.18550725 0.26613882 1.0 2140 tags=36%, list=14%, signal=41% NEGATIVE REGULATION OF METAPHASE/ANAPHASE TRANSITION OF CELL CYCLE%GOBP%GO:1902100 NEGATIVE REGULATION OF METAPHASE/ANAPHASE TRANSITION OF CELL CYCLE%GOBP%GO:1902100 15 -0.49826527 -1.2201263 0.22115384 0.26593062 1.0 3584 tags=47%, list=24%, signal=61% PID_CXCR3_PATHWAY%MSIGDB_C2%PID_CXCR3_PATHWAY PID_CXCR3_PATHWAY%MSIGDB_C2%PID_CXCR3_PATHWAY 42 -0.3972831 -1.2197484 0.16438356 0.26621848 1.0 1317 tags=17%, list=9%, signal=18% REGULATION OF I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0043122 REGULATION OF I-KAPPAB KINASE/NF-KAPPAB SIGNALING%GOBP%GO:0043122 200 -0.31528994 -1.219707 0.043010753 0.2660746 1.0 1312 tags=18%, list=9%, signal=19% STEROL BIOSYNTHETIC PROCESS%GOBP%GO:0016126 STEROL BIOSYNTHETIC PROCESS%GOBP%GO:0016126 32 -0.4241196 -1.2196786 0.1486068 0.26589808 1.0 1994 tags=25%, list=13%, signal=29% POSITIVE REGULATION OF INTERLEUKIN-6 PRODUCTION%GOBP%GO:0032755 POSITIVE REGULATION OF INTERLEUKIN-6 PRODUCTION%GOBP%GO:0032755 32 -0.4274692 -1.2191508 0.17699115 0.26632324 1.0 2755 tags=41%, list=18%, signal=50% ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS%REACTOME DATABASE ID RELEASE 60%5617472 ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS%REACTOME DATABASE ID RELEASE 60%5617472 88 -0.35197395 -1.2179507 0.11320755 0.26772743 1.0 3326 tags=35%, list=22%, signal=45% IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002377 IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002377 21 -0.46889877 -1.216535 0.18911175 0.26944748 1.0 3863 tags=48%, list=25%, signal=64% JNK (C-JUN KINASES) PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1%REACTOME DATABASE ID RELEASE 60%450321 JNK (C-JUN KINASES) PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1%REACTOME DATABASE ID RELEASE 60%450321 18 -0.49204612 -1.2154979 0.20980926 0.2706525 1.0 2310 tags=33%, list=15%, signal=39% TCF DEPENDENT SIGNALING IN RESPONSE TO WNT%REACTOME DATABASE ID RELEASE 60%201681 TCF DEPENDENT SIGNALING IN RESPONSE TO WNT%REACTOME DATABASE ID RELEASE 60%201681 188 -0.31034175 -1.2131833 0.02970297 0.2736609 1.0 3337 tags=31%, list=22%, signal=39% TOLL LIKE RECEPTOR 3 (TLR3) CASCADE%REACTOME DATABASE ID RELEASE 60%168164 TOLL LIKE RECEPTOR 3 (TLR3) CASCADE%REACTOME DATABASE ID RELEASE 60%168164 98 -0.3376528 -1.2131406 0.10695187 0.27349415 1.0 3875 tags=33%, list=25%, signal=44% POSITIVE REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032760 POSITIVE REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032760 32 -0.4170657 -1.2130929 0.16809116 0.27332905 1.0 2196 tags=34%, list=14%, signal=40% POSITIVE REGULATION OF TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0060261 POSITIVE REGULATION OF TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER%GOBP%GO:0060261 15 -0.50904745 -1.2126243 0.20671834 0.27376124 1.0 3181 tags=47%, list=21%, signal=59% IL1-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL1-MEDIATED SIGNALING EVENTS IL1-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL1-MEDIATED SIGNALING EVENTS 33 -0.4250966 -1.2125069 0.17515923 0.27368104 1.0 3183 tags=30%, list=21%, signal=38% POSITIVE REGULATION OF INTERLEUKIN-1 PRODUCTION%GOBP%GO:0032732 POSITIVE REGULATION OF INTERLEUKIN-1 PRODUCTION%GOBP%GO:0032732 22 -0.4659067 -1.2120118 0.21010639 0.27418935 1.0 849 tags=18%, list=6%, signal=19% IL4%NETPATH%IL4 IL4%NETPATH%IL4 70 -0.3584765 -1.2112939 0.13615024 0.27500382 1.0 3007 tags=33%, list=20%, signal=41% POSITIVE REGULATION OF NF-KAPPAB IMPORT INTO NUCLEUS%GOBP%GO:0042346 POSITIVE REGULATION OF NF-KAPPAB IMPORT INTO NUCLEUS%GOBP%GO:0042346 16 -0.49559835 -1.2105336 0.2536232 0.27579933 1.0 2140 tags=25%, list=14%, signal=29% NEGATIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002707 NEGATIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY%GOBP%GO:0002707 15 -0.5197066 -1.2094331 0.23664123 0.27711794 1.0 2135 tags=47%, list=14%, signal=54% NEGATIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS%GOBP%GO:1901799 NEGATIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS%GOBP%GO:1901799 21 -0.4749906 -1.2092098 0.200542 0.27721712 1.0 3894 tags=43%, list=26%, signal=58% RNA PHOSPHODIESTER BOND HYDROLYSIS, ENDONUCLEOLYTIC%GOBP%GO:0090502 RNA PHOSPHODIESTER BOND HYDROLYSIS, ENDONUCLEOLYTIC%GOBP%GO:0090502 16 -0.5063901 -1.207785 0.20493828 0.2789609 1.0 4067 tags=50%, list=27%, signal=68% FATTY ACID METABOLIC PROCESS%GOBP%GO:0006631 FATTY ACID METABOLIC PROCESS%GOBP%GO:0006631 166 -0.32321823 -1.2074832 0.048543688 0.27921143 1.0 3212 tags=31%, list=21%, signal=39% POSITIVE REGULATION OF INTERLEUKIN-1 BETA PRODUCTION%GOBP%GO:0032731 POSITIVE REGULATION OF INTERLEUKIN-1 BETA PRODUCTION%GOBP%GO:0032731 19 -0.48324874 -1.206926 0.22340426 0.2797771 1.0 849 tags=21%, list=6%, signal=22% REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904356 REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904356 53 -0.38342908 -1.206667 0.1627907 0.2799173 1.0 3588 tags=34%, list=24%, signal=44% NEGATIVE REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051985 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION%GOBP%GO:0051985 19 -0.47674912 -1.2051023 0.20110193 0.28201556 1.0 3584 tags=42%, list=24%, signal=55% NEGATIVE REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903038 NEGATIVE REGULATION OF LEUKOCYTE CELL-CELL ADHESION%GOBP%GO:1903038 55 -0.38054585 -1.2031355 0.14801444 0.2845412 1.0 2135 tags=36%, list=14%, signal=42% REGULATION OF LYMPHOCYTE DIFFERENTIATION%GOBP%GO:0045619 REGULATION OF LYMPHOCYTE DIFFERENTIATION%GOBP%GO:0045619 71 -0.3550527 -1.2010984 0.14903846 0.28723136 1.0 2167 tags=39%, list=14%, signal=46% PID_FOXM1_PATHWAY%MSIGDB_C2%PID_FOXM1_PATHWAY PID_FOXM1_PATHWAY%MSIGDB_C2%PID_FOXM1_PATHWAY 38 -0.40666384 -1.2008632 0.19636364 0.28732118 1.0 1143 tags=34%, list=8%, signal=37% POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:2001244 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:2001244 37 -0.4117991 -1.2008227 0.16487455 0.2871461 1.0 3486 tags=43%, list=23%, signal=56% NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002698 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS%GOBP%GO:0002698 57 -0.3726361 -1.200651 0.13253012 0.28715748 1.0 2135 tags=28%, list=14%, signal=33% TRIF-MEDIATED TLR3 TLR4 SIGNALING%REACTOME%R-HSA-937061.1 TRIF-MEDIATED TLR3 TLR4 SIGNALING%REACTOME%R-HSA-937061.1 98 -0.3376528 -1.2004783 0.082840234 0.28719616 1.0 3875 tags=33%, list=25%, signal=44% VIRAL LIFE CYCLE%GOBP%GO:0019058 VIRAL LIFE CYCLE%GOBP%GO:0019058 123 -0.3282202 -1.2000383 0.11627907 0.28765747 1.0 4332 tags=40%, list=28%, signal=55% REGULATION OF MITOCHONDRION ORGANIZATION%GOBP%GO:0010821 REGULATION OF MITOCHONDRION ORGANIZATION%GOBP%GO:0010821 177 -0.3112715 -1.1997656 0.064935066 0.28781217 1.0 3014 tags=27%, list=20%, signal=33% SINGLE-ORGANISM MEMBRANE FUSION%GOBP%GO:0044801 SINGLE-ORGANISM MEMBRANE FUSION%GOBP%GO:0044801 98 -0.34130135 -1.19976 0.10429448 0.2875956 1.0 2783 tags=22%, list=18%, signal=27% MYD88-INDEPENDENT TLR3 TLR4 CASCADE%REACTOME%R-HSA-166166.1 MYD88-INDEPENDENT TLR3 TLR4 CASCADE%REACTOME%R-HSA-166166.1 98 -0.3376528 -1.1992184 0.10285714 0.28810048 1.0 3875 tags=33%, list=25%, signal=44% BIOCARTA_RACCYCD_PATHWAY%MSIGDB_C2%BIOCARTA_RACCYCD_PATHWAY BIOCARTA_RACCYCD_PATHWAY%MSIGDB_C2%BIOCARTA_RACCYCD_PATHWAY 26 -0.44290915 -1.1977506 0.1859155 0.28991282 1.0 1888 tags=38%, list=12%, signal=44% POSITIVE REGULATION OF IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002639 POSITIVE REGULATION OF IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002639 17 -0.48878142 -1.1974095 0.2284264 0.29018262 1.0 3023 tags=35%, list=20%, signal=44% RESPONSE TO ARSENIC-CONTAINING SUBSTANCE%GOBP%GO:0046685 RESPONSE TO ARSENIC-CONTAINING SUBSTANCE%GOBP%GO:0046685 15 -0.49417442 -1.1973219 0.2313253 0.29005492 1.0 3867 tags=40%, list=25%, signal=54% NUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009165 NUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009165 107 -0.32674354 -1.196622 0.07058824 0.2908278 1.0 2767 tags=36%, list=18%, signal=43% ACTIVATED TLR4 SIGNALLING%REACTOME%R-HSA-166054.1 ACTIVATED TLR4 SIGNALLING%REACTOME%R-HSA-166054.1 113 -0.3314246 -1.1964635 0.066176474 0.29081294 1.0 3626 tags=32%, list=24%, signal=42% CHROMOSOME ORGANIZATION INVOLVED IN MEIOTIC CELL CYCLE%GOBP%GO:0070192 CHROMOSOME ORGANIZATION INVOLVED IN MEIOTIC CELL CYCLE%GOBP%GO:0070192 17 -0.49269143 -1.1962749 0.21153846 0.29085505 1.0 3348 tags=53%, list=22%, signal=68% ACYL-COA BIOSYNTHETIC PROCESS%GOBP%GO:0071616 ACYL-COA BIOSYNTHETIC PROCESS%GOBP%GO:0071616 30 -0.4254611 -1.1940951 0.18987341 0.29385343 1.0 1392 tags=23%, list=9%, signal=26% KSRP (KHSRP) BINDS AND DESTABILIZES MRNA%REACTOME DATABASE ID RELEASE 60%450604 KSRP (KHSRP) BINDS AND DESTABILIZES MRNA%REACTOME DATABASE ID RELEASE 60%450604 17 -0.48810163 -1.1927946 0.22894737 0.2955631 1.0 554 tags=18%, list=4%, signal=18% RESPONSE TO BACTERIUM%GOBP%GO:0009617 RESPONSE TO BACTERIUM%GOBP%GO:0009617 196 -0.31001997 -1.1920774 0.05154639 0.29636508 1.0 2227 tags=22%, list=15%, signal=25% PID_IL6_7_PATHWAY%MSIGDB_C2%PID_IL6_7_PATHWAY PID_IL6_7_PATHWAY%MSIGDB_C2%PID_IL6_7_PATHWAY 43 -0.40155926 -1.1916412 0.19097222 0.29674545 1.0 294 tags=9%, list=2%, signal=9% LEUKOCYTE CHEMOTAXIS%GOBP%GO:0030595 LEUKOCYTE CHEMOTAXIS%GOBP%GO:0030595 80 -0.35080588 -1.1909349 0.10952381 0.2975672 1.0 1954 tags=23%, list=13%, signal=26% HDR THROUGH SINGLE STRAND ANNEALING (SSA)%REACTOME DATABASE ID RELEASE 60%5685938 HDR THROUGH SINGLE STRAND ANNEALING (SSA)%REACTOME DATABASE ID RELEASE 60%5685938 35 -0.41206148 -1.1903447 0.1952862 0.29817355 1.0 5059 tags=63%, list=33%, signal=94% CELL-CELL RECOGNITION%GOBP%GO:0009988 CELL-CELL RECOGNITION%GOBP%GO:0009988 23 -0.45679882 -1.1902888 0.22608696 0.29803026 1.0 713 tags=13%, list=5%, signal=14% DNA DAMAGE RESPONSE, SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR%GOBP%GO:0030330 DNA DAMAGE RESPONSE, SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR%GOBP%GO:0030330 77 -0.34755316 -1.1896297 0.140625 0.2987393 1.0 4807 tags=48%, list=32%, signal=70% TNFSF8%IOB%TNFSF8 TNFSF8%IOB%TNFSF8 19 -0.4717928 -1.1895876 0.2549505 0.29856768 1.0 1312 tags=16%, list=9%, signal=17% REGULATION OF DNA-DEPENDENT DNA REPLICATION%GOBP%GO:0090329 REGULATION OF DNA-DEPENDENT DNA REPLICATION%GOBP%GO:0090329 36 -0.40635514 -1.1892314 0.20833333 0.29886767 1.0 879 tags=19%, list=6%, signal=21% TOLL-LIKE RECEPTORS CASCADES%REACTOME DATABASE ID RELEASE 60%168898 TOLL-LIKE RECEPTORS CASCADES%REACTOME DATABASE ID RELEASE 60%168898 141 -0.32074115 -1.1892155 0.066176474 0.29865363 1.0 3626 tags=32%, list=24%, signal=42% POSITIVE REGULATION OF DNA REPAIR%GOBP%GO:0045739 POSITIVE REGULATION OF DNA REPAIR%GOBP%GO:0045739 36 -0.41232488 -1.1880033 0.19377163 0.30016503 1.0 2310 tags=22%, list=15%, signal=26% NEGATIVE REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031111 NEGATIVE REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031111 16 -0.4901156 -1.1837124 0.22727273 0.30626005 1.0 3210 tags=38%, list=21%, signal=47% DOLICHOL-LINKED OLIGOSACCHARIDE BIOSYNTHETIC PROCESS%GOBP%GO:0006488 DOLICHOL-LINKED OLIGOSACCHARIDE BIOSYNTHETIC PROCESS%GOBP%GO:0006488 18 -0.4808192 -1.1834571 0.24210526 0.3063794 1.0 4140 tags=33%, list=27%, signal=46% ALPHA-AMINO ACID METABOLIC PROCESS%GOBP%GO:1901605 ALPHA-AMINO ACID METABOLIC PROCESS%GOBP%GO:1901605 141 -0.32058808 -1.1830068 0.05882353 0.30682832 1.0 3717 tags=32%, list=24%, signal=42% SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)%REACTOME DATABASE ID RELEASE 60%162710 SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)%REACTOME DATABASE ID RELEASE 60%162710 15 -0.49761778 -1.1819869 0.24685138 0.3081882 1.0 4167 tags=40%, list=27%, signal=55% SIGNAL TRANSDUCTION INVOLVED IN DNA INTEGRITY CHECKPOINT%GOBP%GO:0072401 SIGNAL TRANSDUCTION INVOLVED IN DNA INTEGRITY CHECKPOINT%GOBP%GO:0072401 61 -0.35871646 -1.1810185 0.18431373 0.30936712 1.0 4450 tags=46%, list=29%, signal=65% NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS%GOBP%GO:1902042 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS%GOBP%GO:1902042 26 -0.44431308 -1.1801335 0.22089553 0.31037608 1.0 285 tags=15%, list=2%, signal=16% NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070664 NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION%GOBP%GO:0070664 33 -0.4144364 -1.1792815 0.2032258 0.31139004 1.0 2135 tags=36%, list=14%, signal=42% CELLULAR SENESCENCE%REACTOME DATABASE ID RELEASE 60%2559583 CELLULAR SENESCENCE%REACTOME DATABASE ID RELEASE 60%2559583 155 -0.31173682 -1.178237 0.114754096 0.31270528 1.0 3357 tags=32%, list=22%, signal=40% SEXUAL REPRODUCTION%GOBP%GO:0019953 SEXUAL REPRODUCTION%GOBP%GO:0019953 179 -0.30282393 -1.1778721 0.08421053 0.31301552 1.0 3482 tags=27%, list=23%, signal=35% NEGATIVE REGULATION OF SISTER CHROMATID SEGREGATION%GOBP%GO:0033046 NEGATIVE REGULATION OF SISTER CHROMATID SEGREGATION%GOBP%GO:0033046 19 -0.47674912 -1.177846 0.24250682 0.31280136 1.0 3584 tags=42%, list=24%, signal=55% REGULATION OF LIPID STORAGE%GOBP%GO:0010883 REGULATION OF LIPID STORAGE%GOBP%GO:0010883 31 -0.41306084 -1.1769707 0.19937694 0.31395748 1.0 430 tags=13%, list=3%, signal=13% FATTY-ACYL-COA METABOLIC PROCESS%GOBP%GO:0035337 FATTY-ACYL-COA METABOLIC PROCESS%GOBP%GO:0035337 29 -0.41796792 -1.1764463 0.190625 0.31451786 1.0 1392 tags=21%, list=9%, signal=23% IRON ION HOMEOSTASIS%GOBP%GO:0055072 IRON ION HOMEOSTASIS%GOBP%GO:0055072 51 -0.37022623 -1.1763475 0.192 0.31442443 1.0 2560 tags=25%, list=17%, signal=31% MACROMOLECULE DEACYLATION%GOBP%GO:0098732 MACROMOLECULE DEACYLATION%GOBP%GO:0098732 40 -0.38657305 -1.1762214 0.21352313 0.31437406 1.0 4300 tags=30%, list=28%, signal=42% PID_HDAC_CLASSI_PATHWAY%MSIGDB_C2%PID_HDAC_CLASSI_PATHWAY PID_HDAC_CLASSI_PATHWAY%MSIGDB_C2%PID_HDAC_CLASSI_PATHWAY 63 -0.35488093 -1.1755141 0.16182573 0.31516254 1.0 3291 tags=29%, list=22%, signal=36% FOXM1 TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXM1 TRANSCRIPTION FACTOR NETWORK FOXM1 TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXM1 TRANSCRIPTION FACTOR NETWORK 40 -0.3955569 -1.175277 0.18275861 0.31530458 1.0 1143 tags=33%, list=8%, signal=35% REGULATION OF DNA RECOMBINATION%GOBP%GO:0000018 REGULATION OF DNA RECOMBINATION%GOBP%GO:0000018 41 -0.39733896 -1.1746726 0.20522387 0.31592548 1.0 3023 tags=29%, list=20%, signal=36% ESTABLISHMENT OF PROTEIN LOCALIZATION TO PEROXISOME%GOBP%GO:0072663 ESTABLISHMENT OF PROTEIN LOCALIZATION TO PEROXISOME%GOBP%GO:0072663 16 -0.48296794 -1.1743922 0.24264705 0.31609637 1.0 5275 tags=56%, list=35%, signal=86% CXCR3-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CXCR3-MEDIATED SIGNALING EVENTS CXCR3-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CXCR3-MEDIATED SIGNALING EVENTS 37 -0.39241526 -1.1738409 0.20700637 0.31667298 1.0 1283 tags=16%, list=8%, signal=18% PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0042787 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN-DEPENDENT PROTEIN CATABOLIC PROCESS%GOBP%GO:0042787 118 -0.32963702 -1.1734686 0.15447155 0.31696677 1.0 3357 tags=25%, list=22%, signal=31% VACUOLAR ACIDIFICATION%GOBP%GO:0007035 VACUOLAR ACIDIFICATION%GOBP%GO:0007035 15 -0.5071632 -1.1733215 0.25345623 0.31696153 1.0 4520 tags=53%, list=30%, signal=76% SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR%GOBP%GO:0072331 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR%GOBP%GO:0072331 105 -0.32597002 -1.1723077 0.098265894 0.3183061 1.0 3524 tags=31%, list=23%, signal=41% ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT (ESCRT)%REACTOME DATABASE ID RELEASE 60%917729 ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT (ESCRT)%REACTOME DATABASE ID RELEASE 60%917729 28 -0.42008808 -1.1717558 0.20527859 0.3188852 1.0 5115 tags=50%, list=34%, signal=75% TRANSPORT OF VIRUS%GOBP%GO:0046794 TRANSPORT OF VIRUS%GOBP%GO:0046794 51 -0.37178984 -1.1709867 0.18888889 0.3198119 1.0 4440 tags=47%, list=29%, signal=66% TOLL LIKE RECEPTOR 4 (TLR4) CASCADE%REACTOME%R-HSA-166016.1 TOLL LIKE RECEPTOR 4 (TLR4) CASCADE%REACTOME%R-HSA-166016.1 122 -0.31665555 -1.1701813 0.10810811 0.32080486 1.0 3626 tags=32%, list=24%, signal=42% REGULATION OF TP53 EXPRESSION AND DEGRADATION%REACTOME DATABASE ID RELEASE 60%6806003 REGULATION OF TP53 EXPRESSION AND DEGRADATION%REACTOME DATABASE ID RELEASE 60%6806003 37 -0.3993749 -1.1701394 0.20532319 0.3206267 1.0 2803 tags=22%, list=18%, signal=26% POSITIVE REGULATION OF INTERLEUKIN-1 SECRETION%GOBP%GO:0050716 POSITIVE REGULATION OF INTERLEUKIN-1 SECRETION%GOBP%GO:0050716 18 -0.4702966 -1.1700863 0.25833333 0.32046446 1.0 849 tags=17%, list=6%, signal=18% SIGNAL TRANSDUCTION INVOLVED IN DNA DAMAGE CHECKPOINT%GOBP%GO:0072422 SIGNAL TRANSDUCTION INVOLVED IN DNA DAMAGE CHECKPOINT%GOBP%GO:0072422 61 -0.35871646 -1.1699967 0.16597511 0.32033503 1.0 4450 tags=46%, list=29%, signal=65% REGULATION OF SISTER CHROMATID COHESION%GOBP%GO:0007063 REGULATION OF SISTER CHROMATID COHESION%GOBP%GO:0007063 19 -0.47175777 -1.1694437 0.2445055 0.32096124 1.0 2423 tags=32%, list=16%, signal=38% POSITIVE REGULATION OF PHAGOCYTOSIS%GOBP%GO:0050766 POSITIVE REGULATION OF PHAGOCYTOSIS%GOBP%GO:0050766 27 -0.41871956 -1.1681749 0.2379518 0.3226665 1.0 2929 tags=30%, list=19%, signal=37% NUCLEAR ENVELOPE ORGANIZATION%GOBP%GO:0006998 NUCLEAR ENVELOPE ORGANIZATION%GOBP%GO:0006998 69 -0.35951066 -1.168136 0.21363637 0.3224909 1.0 4293 tags=39%, list=28%, signal=54% NEGATIVE REGULATION OF CHROMOSOME SEPARATION%GOBP%GO:1905819 NEGATIVE REGULATION OF CHROMOSOME SEPARATION%GOBP%GO:1905819 15 -0.49826527 -1.1676481 0.28282827 0.32297894 1.0 3584 tags=47%, list=24%, signal=61% PROCESSING OF INTRONLESS PRE-MRNAS%REACTOME%R-HSA-77595.2 PROCESSING OF INTRONLESS PRE-MRNAS%REACTOME%R-HSA-77595.2 19 -0.4616169 -1.1666626 0.24396783 0.3242433 1.0 5523 tags=53%, list=36%, signal=83% NEGATIVE REGULATION OF MITOTIC METAPHASE/ANAPHASE TRANSITION%GOBP%GO:0045841 NEGATIVE REGULATION OF MITOTIC METAPHASE/ANAPHASE TRANSITION%GOBP%GO:0045841 15 -0.4982653 -1.1663183 0.27139366 0.32446954 1.0 3584 tags=47%, list=24%, signal=61% IL5%NETPATH%IL5 IL5%NETPATH%IL5 58 -0.3559657 -1.1656615 0.20083682 0.32518142 1.0 3544 tags=31%, list=23%, signal=40% NEGATIVE REGULATION OF MITOTIC SISTER CHROMATID SEPARATION%GOBP%GO:2000816 NEGATIVE REGULATION OF MITOTIC SISTER CHROMATID SEPARATION%GOBP%GO:2000816 15 -0.4982653 -1.1641985 0.26822916 0.32725295 1.0 3584 tags=47%, list=24%, signal=61% REGULATION OF IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002637 REGULATION OF IMMUNOGLOBULIN PRODUCTION%GOBP%GO:0002637 20 -0.4448801 -1.1640685 0.2538071 0.3272192 1.0 1611 tags=20%, list=11%, signal=22% TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS%REACTOME DATABASE ID RELEASE 60%452723 TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS%REACTOME DATABASE ID RELEASE 60%452723 27 -0.42176527 -1.1635292 0.23283581 0.32777905 1.0 2682 tags=37%, list=18%, signal=45% REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION%REACTOME%R-HSA-6804756.1 REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION%REACTOME%R-HSA-6804756.1 87 -0.3362132 -1.1633391 0.1356784 0.32779917 1.0 3127 tags=33%, list=21%, signal=42% METHYLATION%GOBP%GO:0032259 METHYLATION%GOBP%GO:0032259 121 -0.3245555 -1.1630744 0.1292517 0.32795417 1.0 4752 tags=38%, list=31%, signal=55% RANKL%NETPATH%RANKL RANKL%NETPATH%RANKL 82 -0.33574674 -1.1619064 0.18579236 0.32950854 1.0 2203 tags=22%, list=14%, signal=26% REGULATION OF DOUBLE-STRAND BREAK REPAIR%GOBP%GO:2000779 REGULATION OF DOUBLE-STRAND BREAK REPAIR%GOBP%GO:2000779 40 -0.40243635 -1.1616998 0.2129964 0.32958093 1.0 2772 tags=35%, list=18%, signal=43% LONG-CHAIN FATTY-ACYL-COA METABOLIC PROCESS%GOBP%GO:0035336 LONG-CHAIN FATTY-ACYL-COA METABOLIC PROCESS%GOBP%GO:0035336 18 -0.47214386 -1.1589856 0.2794872 0.3335528 1.0 1392 tags=28%, list=9%, signal=31% PHAGOSOME ACIDIFICATION%GOBP%GO:0090383 PHAGOSOME ACIDIFICATION%GOBP%GO:0090383 23 -0.43714687 -1.1575567 0.25675675 0.33561108 1.0 4520 tags=43%, list=30%, signal=62% PLASMA LIPOPROTEIN CLEARANCE%REACTOME%R-HSA-8964043.1 PLASMA LIPOPROTEIN CLEARANCE%REACTOME%R-HSA-8964043.1 28 -0.41866606 -1.1567837 0.24269006 0.33657885 1.0 3990 tags=43%, list=26%, signal=58% ORGANELLE MEMBRANE FUSION%GOBP%GO:0090174 ORGANELLE MEMBRANE FUSION%GOBP%GO:0090174 81 -0.33933863 -1.1563557 0.18592964 0.3370064 1.0 2783 tags=23%, list=18%, signal=29% POSITIVE REGULATION OF PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:1903955 POSITIVE REGULATION OF PROTEIN TARGETING TO MITOCHONDRION%GOBP%GO:1903955 70 -0.35266516 -1.1562891 0.18303572 0.33684215 1.0 3190 tags=29%, list=21%, signal=36% METABOLISM OF WATER-SOLUBLE VITAMINS AND COFACTORS%REACTOME DATABASE ID RELEASE 60%196849 METABOLISM OF WATER-SOLUBLE VITAMINS AND COFACTORS%REACTOME DATABASE ID RELEASE 60%196849 106 -0.31719917 -1.1544088 0.12643678 0.33959812 1.0 2688 tags=28%, list=18%, signal=34% DISEASES ASSOCIATED WITH THE TLR SIGNALING CASCADE%REACTOME%R-HSA-5602358.1 DISEASES ASSOCIATED WITH THE TLR SIGNALING CASCADE%REACTOME%R-HSA-5602358.1 24 -0.43603426 -1.1542082 0.23054755 0.33965796 1.0 3332 tags=42%, list=22%, signal=53% PROTEIN LOCALIZATION TO PEROXISOME%GOBP%GO:0072662 PROTEIN LOCALIZATION TO PEROXISOME%GOBP%GO:0072662 16 -0.48296794 -1.1539359 0.28433734 0.3398287 1.0 5275 tags=56%, list=35%, signal=86% VESICLE FUSION%GOBP%GO:0006906 VESICLE FUSION%GOBP%GO:0006906 78 -0.34209454 -1.15368 0.17889908 0.33997744 1.0 1203 tags=13%, list=8%, signal=14% POSITIVE REGULATION OF INTERLEUKIN-1 BETA SECRETION%GOBP%GO:0050718 POSITIVE REGULATION OF INTERLEUKIN-1 BETA SECRETION%GOBP%GO:0050718 16 -0.48922652 -1.1534923 0.294686 0.3399939 1.0 849 tags=19%, list=6%, signal=20% NEGATIVE REGULATION OF MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0033048 NEGATIVE REGULATION OF MITOTIC SISTER CHROMATID SEGREGATION%GOBP%GO:0033048 17 -0.46176845 -1.1514684 0.27371272 0.342924 1.0 3584 tags=41%, list=24%, signal=54% PROTEIN TARGETING TO PEROXISOME%GOBP%GO:0006625 PROTEIN TARGETING TO PEROXISOME%GOBP%GO:0006625 16 -0.48296794 -1.1488717 0.29116946 0.34693804 1.0 5275 tags=56%, list=35%, signal=86% AXONEMAL DYNEIN COMPLEX ASSEMBLY%GOBP%GO:0070286 AXONEMAL DYNEIN COMPLEX ASSEMBLY%GOBP%GO:0070286 17 -0.46638772 -1.1481825 0.276808 0.34778917 1.0 5375 tags=47%, list=35%, signal=73% MONOSACCHARIDE BIOSYNTHETIC PROCESS%GOBP%GO:0046364 MONOSACCHARIDE BIOSYNTHETIC PROCESS%GOBP%GO:0046364 40 -0.3839076 -1.1479471 0.21708184 0.3478899 1.0 3546 tags=33%, list=23%, signal=42% BIOCARTA_KERATINOCYTE_PATHWAY%MSIGDB_C2%BIOCARTA_KERATINOCYTE_PATHWAY BIOCARTA_KERATINOCYTE_PATHWAY%MSIGDB_C2%BIOCARTA_KERATINOCYTE_PATHWAY 44 -0.36901864 -1.1473714 0.21863799 0.34858176 1.0 2857 tags=23%, list=19%, signal=28% AMINE CATABOLIC PROCESS%GOBP%GO:0009310 AMINE CATABOLIC PROCESS%GOBP%GO:0009310 18 -0.45079592 -1.147242 0.2948403 0.34854692 1.0 3256 tags=33%, list=21%, signal=42% NEGATIVE REGULATION OF DEFENSE RESPONSE%GOBP%GO:0031348 NEGATIVE REGULATION OF DEFENSE RESPONSE%GOBP%GO:0031348 74 -0.34241647 -1.147083 0.17272727 0.34853387 1.0 1441 tags=23%, list=9%, signal=25% INFLAMMATORY RESPONSE%GOBP%GO:0006954 INFLAMMATORY RESPONSE%GOBP%GO:0006954 188 -0.29838136 -1.1469063 0.14457831 0.34855953 1.0 1387 tags=16%, list=9%, signal=17% ST_FAS_SIGNALING_PATHWAY%MSIGDB_C2%ST_FAS_SIGNALING_PATHWAY ST_FAS_SIGNALING_PATHWAY%MSIGDB_C2%ST_FAS_SIGNALING_PATHWAY 60 -0.35917228 -1.1467563 0.19742489 0.3485579 1.0 3346 tags=30%, list=22%, signal=38% ONCOGENE INDUCED SENESCENCE%REACTOME%R-HSA-2559585.4 ONCOGENE INDUCED SENESCENCE%REACTOME%R-HSA-2559585.4 30 -0.41376907 -1.1461395 0.24119242 0.34931266 1.0 2247 tags=27%, list=15%, signal=31% PLATELET SENSITIZATION BY LDL%REACTOME DATABASE ID RELEASE 60%432142 PLATELET SENSITIZATION BY LDL%REACTOME DATABASE ID RELEASE 60%432142 15 -0.48255298 -1.1448715 0.26717559 0.35115844 1.0 2252 tags=20%, list=15%, signal=23% CENTROSOME CYCLE%GOBP%GO:0007098 CENTROSOME CYCLE%GOBP%GO:0007098 68 -0.34649706 -1.1446627 0.1875 0.3512344 1.0 3019 tags=31%, list=20%, signal=38% PROTEIN EXIT FROM ENDOPLASMIC RETICULUM%GOBP%GO:0032527 PROTEIN EXIT FROM ENDOPLASMIC RETICULUM%GOBP%GO:0032527 21 -0.44143382 -1.1442696 0.27222222 0.35161388 1.0 3204 tags=33%, list=21%, signal=42% INTERLEUKIN SIGNALING PATHWAY%PANTHER PATHWAY%P00036 INTERLEUKIN SIGNALING PATHWAY%PANTHER PATHWAY%P00036 75 -0.3378426 -1.143173 0.15048544 0.35312748 1.0 3029 tags=31%, list=20%, signal=38% NEGATIVE REGULATION OF DNA-DEPENDENT DNA REPLICATION%GOBP%GO:2000104 NEGATIVE REGULATION OF DNA-DEPENDENT DNA REPLICATION%GOBP%GO:2000104 17 -0.4778238 -1.1425627 0.29736212 0.35389543 1.0 400 tags=18%, list=3%, signal=18% SIGNAL TRANSDUCTION INVOLVED IN MITOTIC DNA DAMAGE CHECKPOINT%GOBP%GO:1902402 SIGNAL TRANSDUCTION INVOLVED IN MITOTIC DNA DAMAGE CHECKPOINT%GOBP%GO:1902402 59 -0.3452505 -1.141999 0.21115538 0.35450518 1.0 4450 tags=44%, list=29%, signal=62% CXCR4%IOB%CXCR4 CXCR4%IOB%CXCR4 93 -0.32124424 -1.1419201 0.16292135 0.35437202 1.0 2451 tags=26%, list=16%, signal=31% THIOESTER BIOSYNTHETIC PROCESS%GOBP%GO:0035384 THIOESTER BIOSYNTHETIC PROCESS%GOBP%GO:0035384 30 -0.4254611 -1.1400564 0.24924925 0.35716897 1.0 1392 tags=23%, list=9%, signal=26% AMMONIUM ION METABOLIC PROCESS%GOBP%GO:0097164 AMMONIUM ION METABOLIC PROCESS%GOBP%GO:0097164 124 -0.31418356 -1.1394923 0.15492958 0.35785234 1.0 1768 tags=15%, list=12%, signal=17% IONOTROPIC GLUTAMATE RECEPTOR PATHWAY%PANTHER PATHWAY%P00037 IONOTROPIC GLUTAMATE RECEPTOR PATHWAY%PANTHER PATHWAY%P00037 28 -0.40687212 -1.13932 0.24709302 0.35786486 1.0 2783 tags=25%, list=18%, signal=31% POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS%GOBP%GO:0002690 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS%GOBP%GO:0002690 62 -0.34397027 -1.1392314 0.199187 0.35777733 1.0 887 tags=21%, list=6%, signal=22% DNA DAMAGE RESPONSE, SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR RESULTING IN CELL CYCLE ARREST%GOBP%GO:0006977 DNA DAMAGE RESPONSE, SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR RESULTING IN CELL CYCLE ARREST%GOBP%GO:0006977 58 -0.34568825 -1.139181 0.18431373 0.3576023 1.0 4450 tags=45%, list=29%, signal=63% UBIQUITIN-DEPENDENT ERAD PATHWAY%GOBP%GO:0030433 UBIQUITIN-DEPENDENT ERAD PATHWAY%GOBP%GO:0030433 56 -0.35315558 -1.136807 0.21487603 0.36143166 1.0 3204 tags=18%, list=21%, signal=23% NEGATIVE REGULATION OF IMMUNE RESPONSE%GOBP%GO:0050777 NEGATIVE REGULATION OF IMMUNE RESPONSE%GOBP%GO:0050777 60 -0.3451188 -1.1363264 0.20300752 0.3619942 1.0 2864 tags=42%, list=19%, signal=51% REGULATION OF HSF1-MEDIATED HEAT SHOCK RESPONSE%REACTOME%R-HSA-3371453.1 REGULATION OF HSF1-MEDIATED HEAT SHOCK RESPONSE%REACTOME%R-HSA-3371453.1 61 -0.34738865 -1.1362398 0.2616034 0.36186337 1.0 4867 tags=44%, list=32%, signal=65% PID_TELOMERASE_PATHWAY%MSIGDB_C2%PID_TELOMERASE_PATHWAY PID_TELOMERASE_PATHWAY%MSIGDB_C2%PID_TELOMERASE_PATHWAY 65 -0.34607133 -1.1359607 0.19753087 0.36205658 1.0 3209 tags=32%, list=21%, signal=41% PROTEIN TETRAMERIZATION%GOBP%GO:0051262 PROTEIN TETRAMERIZATION%GOBP%GO:0051262 83 -0.33918464 -1.1328019 0.18627451 0.36700007 1.0 2088 tags=28%, list=14%, signal=32% GLYCERALDEHYDE-3-PHOSPHATE METABOLIC PROCESS%GOBP%GO:0019682 GLYCERALDEHYDE-3-PHOSPHATE METABOLIC PROCESS%GOBP%GO:0019682 15 -0.4653683 -1.1319628 0.29473683 0.36810178 1.0 6392 tags=73%, list=42%, signal=126% MELANOSOME LOCALIZATION%GOBP%GO:0032400 MELANOSOME LOCALIZATION%GOBP%GO:0032400 16 -0.46296456 -1.1314967 0.29274005 0.36862245 1.0 5603 tags=63%, list=37%, signal=99% GLUCOSE METABOLISM%REACTOME DATABASE ID RELEASE 60%70326 GLUCOSE METABOLISM%REACTOME DATABASE ID RELEASE 60%70326 73 -0.33197328 -1.129887 0.21212122 0.37098196 1.0 4973 tags=40%, list=33%, signal=59% CTLA4 INHIBITORY SIGNALING%REACTOME DATABASE ID RELEASE 60%389513 CTLA4 INHIBITORY SIGNALING%REACTOME DATABASE ID RELEASE 60%389513 21 -0.44124886 -1.1286455 0.28010473 0.37279963 1.0 1204 tags=24%, list=8%, signal=26% OLIGOSACCHARIDE-LIPID INTERMEDIATE BIOSYNTHETIC PROCESS%GOBP%GO:0006490 OLIGOSACCHARIDE-LIPID INTERMEDIATE BIOSYNTHETIC PROCESS%GOBP%GO:0006490 19 -0.4530151 -1.1265363 0.2948718 0.37603137 1.0 4140 tags=32%, list=27%, signal=43% SYNTHESIS OF PC%REACTOME%R-HSA-1483191.4 SYNTHESIS OF PC%REACTOME%R-HSA-1483191.4 27 -0.41678214 -1.1258259 0.26283988 0.37697822 1.0 2221 tags=22%, list=15%, signal=26% RESPONSE TO MISFOLDED PROTEIN%GOBP%GO:0051788 RESPONSE TO MISFOLDED PROTEIN%GOBP%GO:0051788 21 -0.44207367 -1.1245191 0.3091922 0.37892315 1.0 4315 tags=38%, list=28%, signal=53% GENE SILENCING BY MIRNA%GOBP%GO:0035195 GENE SILENCING BY MIRNA%GOBP%GO:0035195 30 -0.40609622 -1.1243136 0.27462685 0.378997 1.0 2940 tags=30%, list=19%, signal=37% MULTIVESICULAR BODY ORGANIZATION%GOBP%GO:0036257 MULTIVESICULAR BODY ORGANIZATION%GOBP%GO:0036257 28 -0.40504372 -1.1238941 0.26239067 0.37947634 1.0 5115 tags=46%, list=34%, signal=70% PROTEIN DEACYLATION%GOBP%GO:0035601 PROTEIN DEACYLATION%GOBP%GO:0035601 40 -0.38657305 -1.1237996 0.22614841 0.3793807 1.0 4300 tags=30%, list=28%, signal=42% ACTIVATION OF BH3-ONLY PROTEINS%REACTOME DATABASE ID RELEASE 60%114452 ACTIVATION OF BH3-ONLY PROTEINS%REACTOME DATABASE ID RELEASE 60%114452 30 -0.40871495 -1.1231829 0.2611465 0.38020703 1.0 2172 tags=23%, list=14%, signal=27% DISEASES OF IMMUNE SYSTEM%REACTOME DATABASE ID RELEASE 60%5260271 DISEASES OF IMMUNE SYSTEM%REACTOME DATABASE ID RELEASE 60%5260271 24 -0.43603426 -1.122538 0.30860534 0.38102087 1.0 3332 tags=42%, list=22%, signal=53% DICARBOXYLIC ACID METABOLIC PROCESS%GOBP%GO:0043648 DICARBOXYLIC ACID METABOLIC PROCESS%GOBP%GO:0043648 63 -0.34857956 -1.1217818 0.21524663 0.3820228 1.0 3663 tags=38%, list=24%, signal=50% HALLMARK_PI3K_AKT_MTOR_SIGNALING%MSIGDB_C2%HALLMARK_PI3K_AKT_MTOR_SIGNALING HALLMARK_PI3K_AKT_MTOR_SIGNALING%MSIGDB_C2%HALLMARK_PI3K_AKT_MTOR_SIGNALING 100 -0.3156831 -1.1217664 0.20496894 0.38178256 1.0 3299 tags=32%, list=22%, signal=41% MITOTIC DNA DAMAGE CHECKPOINT%GOBP%GO:0044773 MITOTIC DNA DAMAGE CHECKPOINT%GOBP%GO:0044773 87 -0.31644094 -1.1211629 0.18536586 0.38250694 1.0 4450 tags=45%, list=29%, signal=63% CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY%REACTOME DATABASE ID RELEASE 60%5357769 CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY%REACTOME DATABASE ID RELEASE 60%5357769 25 -0.42595148 -1.1209326 0.3045822 0.3826144 1.0 615 tags=16%, list=4%, signal=17% CYCLIN D ASSOCIATED EVENTS IN G1%REACTOME DATABASE ID RELEASE 60%69231 CYCLIN D ASSOCIATED EVENTS IN G1%REACTOME DATABASE ID RELEASE 60%69231 43 -0.36495548 -1.1205074 0.21799308 0.3830569 1.0 2372 tags=30%, list=16%, signal=36% SIGNALING EVENTS MEDIATED BY HDAC CLASS I%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%SIGNALING EVENTS MEDIATED BY HDAC CLASS I SIGNALING EVENTS MEDIATED BY HDAC CLASS I%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%SIGNALING EVENTS MEDIATED BY HDAC CLASS I 64 -0.3419445 -1.1201967 0.22123894 0.3833372 1.0 3291 tags=28%, list=22%, signal=36% CELLULAR PIGMENTATION%GOBP%GO:0033059 CELLULAR PIGMENTATION%GOBP%GO:0033059 34 -0.39067903 -1.1201266 0.25172412 0.38318807 1.0 5151 tags=47%, list=34%, signal=71% BIOCARTA_AKT_PATHWAY%MSIGDB_C2%BIOCARTA_AKT_PATHWAY BIOCARTA_AKT_PATHWAY%MSIGDB_C2%BIOCARTA_AKT_PATHWAY 21 -0.43298942 -1.1190703 0.30555555 0.3846775 1.0 3007 tags=43%, list=20%, signal=53% SIGNAL TRANSDUCTION INVOLVED IN MITOTIC CELL CYCLE CHECKPOINT%GOBP%GO:0072413 SIGNAL TRANSDUCTION INVOLVED IN MITOTIC CELL CYCLE CHECKPOINT%GOBP%GO:0072413 59 -0.3452505 -1.1185801 0.21568628 0.38524917 1.0 4450 tags=44%, list=29%, signal=62% REGULATION OF HISTONE H3-K4 METHYLATION%GOBP%GO:0051569 REGULATION OF HISTONE H3-K4 METHYLATION%GOBP%GO:0051569 15 -0.48813304 -1.1180122 0.31898734 0.38592124 1.0 3023 tags=33%, list=20%, signal=42% ENDOPLASMIC RETICULUM TO CYTOSOL TRANSPORT%GOBP%GO:1903513 ENDOPLASMIC RETICULUM TO CYTOSOL TRANSPORT%GOBP%GO:1903513 15 -0.4730284 -1.1167886 0.29850745 0.38774446 1.0 3204 tags=33%, list=21%, signal=42% CITRATE METABOLIC PROCESS%GOBP%GO:0006101 CITRATE METABOLIC PROCESS%GOBP%GO:0006101 31 -0.3940284 -1.1167711 0.28235295 0.38749322 1.0 2952 tags=45%, list=19%, signal=56% RETROGRADE PROTEIN TRANSPORT, ER TO CYTOSOL%GOBP%GO:0030970 RETROGRADE PROTEIN TRANSPORT, ER TO CYTOSOL%GOBP%GO:0030970 15 -0.4730284 -1.1156161 0.31218275 0.38922822 1.0 3204 tags=33%, list=21%, signal=42% POSITIVE REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY%GOBP%GO:2001056 POSITIVE REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY%GOBP%GO:2001056 97 -0.31792662 -1.1150423 0.20809248 0.38996404 1.0 2067 tags=22%, list=14%, signal=25% PEPTIDYL-LYSINE ACETYLATION%GOBP%GO:0018394 PEPTIDYL-LYSINE ACETYLATION%GOBP%GO:0018394 66 -0.3374335 -1.1142616 0.22267206 0.39108345 1.0 4265 tags=33%, list=28%, signal=46% INTRACELLULAR SIGNAL TRANSDUCTION INVOLVED IN G1 DNA DAMAGE CHECKPOINT%GOBP%GO:1902400 INTRACELLULAR SIGNAL TRANSDUCTION INVOLVED IN G1 DNA DAMAGE CHECKPOINT%GOBP%GO:1902400 59 -0.3452505 -1.1141696 0.2644628 0.390964 1.0 4450 tags=44%, list=29%, signal=62% G1 PHASE%REACTOME%R-HSA-69236.3 G1 PHASE%REACTOME%R-HSA-69236.3 43 -0.36495548 -1.1130872 0.2638037 0.39263177 1.0 2372 tags=30%, list=16%, signal=36% T CELL SELECTION%GOBP%GO:0045058 T CELL SELECTION%GOBP%GO:0045058 16 -0.4776222 -1.11203 0.3265306 0.39420533 1.0 2461 tags=69%, list=16%, signal=82% MICROTUBULE ORGANIZING CENTER ORGANIZATION%GOBP%GO:0031023 MICROTUBULE ORGANIZING CENTER ORGANIZATION%GOBP%GO:0031023 76 -0.3285307 -1.1112487 0.20454545 0.3953178 1.0 1739 tags=20%, list=11%, signal=22% REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903555 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903555 56 -0.3498544 -1.1104423 0.2480315 0.39649427 1.0 2570 tags=32%, list=17%, signal=39% SIGNAL TRANSDUCTION INVOLVED IN MITOTIC G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0072431 SIGNAL TRANSDUCTION INVOLVED IN MITOTIC G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0072431 59 -0.3452505 -1.1096299 0.24696356 0.39763877 1.0 4450 tags=44%, list=29%, signal=62% FLAGELLATED SPERM MOTILITY%GOBP%GO:0030317 FLAGELLATED SPERM MOTILITY%GOBP%GO:0030317 18 -0.44208622 -1.1082625 0.3084833 0.3998473 1.0 5224 tags=39%, list=34%, signal=59% MODULATION BY VIRUS OF HOST PROCESS%GOBP%GO:0019054 MODULATION BY VIRUS OF HOST PROCESS%GOBP%GO:0019054 19 -0.4465977 -1.1073422 0.32453826 0.4011772 1.0 3737 tags=32%, list=25%, signal=42% PRODUCTION OF MIRNAS INVOLVED IN GENE SILENCING BY MIRNA%GOBP%GO:0035196 PRODUCTION OF MIRNAS INVOLVED IN GENE SILENCING BY MIRNA%GOBP%GO:0035196 15 -0.47827923 -1.1064354 0.33576643 0.40256697 1.0 2940 tags=33%, list=19%, signal=41% GLUCOSE METABOLIC PROCESS%GOBP%GO:0006006 GLUCOSE METABOLIC PROCESS%GOBP%GO:0006006 64 -0.33828434 -1.1058851 0.24311927 0.4032923 1.0 3546 tags=31%, list=23%, signal=41% B CELL ACTIVATION%PANTHER PATHWAY%P00010 B CELL ACTIVATION%PANTHER PATHWAY%P00010 56 -0.3412501 -1.1058404 0.23970038 0.40309227 1.0 3228 tags=34%, list=21%, signal=43% MITOTIC DNA INTEGRITY CHECKPOINT%GOBP%GO:0044774 MITOTIC DNA INTEGRITY CHECKPOINT%GOBP%GO:0044774 94 -0.31250933 -1.1055882 0.23163842 0.40326318 1.0 4450 tags=43%, list=29%, signal=60% REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY INVOLVED IN APOPTOTIC PROCESS%GOBP%GO:1902108 REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY INVOLVED IN APOPTOTIC PROCESS%GOBP%GO:1902108 16 -0.45923367 -1.1055719 0.32233503 0.40300912 1.0 3345 tags=31%, list=22%, signal=40% COMPLEMENT ACTIVATION%GOBP%GO:0006956 COMPLEMENT ACTIVATION%GOBP%GO:0006956 20 -0.4433566 -1.1052201 0.3342318 0.40332702 1.0 946 tags=25%, list=6%, signal=27% PHOSPHATIDYLCHOLINE BIOSYNTHETIC PROCESS%GOBP%GO:0006656 PHOSPHATIDYLCHOLINE BIOSYNTHETIC PROCESS%GOBP%GO:0006656 30 -0.39507407 -1.1049385 0.31176472 0.40357962 1.0 2221 tags=20%, list=15%, signal=23% SIGNAL TRANSDUCTION INVOLVED IN MITOTIC DNA INTEGRITY CHECKPOINT%GOBP%GO:1902403 SIGNAL TRANSDUCTION INVOLVED IN MITOTIC DNA INTEGRITY CHECKPOINT%GOBP%GO:1902403 59 -0.3452505 -1.1039902 0.22357723 0.40497378 1.0 4450 tags=44%, list=29%, signal=62% SPINDLE CHECKPOINT%GOBP%GO:0031577 SPINDLE CHECKPOINT%GOBP%GO:0031577 18 -0.44461572 -1.1039578 0.33248082 0.40474826 1.0 4895 tags=61%, list=32%, signal=90% REGULATION OF HUMORAL IMMUNE RESPONSE%GOBP%GO:0002920 REGULATION OF HUMORAL IMMUNE RESPONSE%GOBP%GO:0002920 39 -0.37102085 -1.10395 0.28873238 0.40447718 1.0 2016 tags=28%, list=13%, signal=32% CELLULAR BIOGENIC AMINE CATABOLIC PROCESS%GOBP%GO:0042402 CELLULAR BIOGENIC AMINE CATABOLIC PROCESS%GOBP%GO:0042402 18 -0.45079592 -1.1007489 0.3178082 0.41000366 1.0 3256 tags=33%, list=21%, signal=42% ACYL CHAIN REMODELLING OF PE%REACTOME DATABASE ID RELEASE 60%1482839 ACYL CHAIN REMODELLING OF PE%REACTOME DATABASE ID RELEASE 60%1482839 21 -0.42870453 -1.1006994 0.3263158 0.40981096 1.0 1768 tags=33%, list=12%, signal=38% RESPONSE TO DSRNA%GOBP%GO:0043331 RESPONSE TO DSRNA%GOBP%GO:0043331 34 -0.37916854 -1.0990502 0.29903537 0.41254163 1.0 2293 tags=29%, list=15%, signal=35% HISTONE H2A ACETYLATION%GOBP%GO:0043968 HISTONE H2A ACETYLATION%GOBP%GO:0043968 15 -0.46266922 -1.0990163 0.34751773 0.41230294 1.0 5712 tags=60%, list=38%, signal=96% PIGMENT GRANULE LOCALIZATION%GOBP%GO:0051875 PIGMENT GRANULE LOCALIZATION%GOBP%GO:0051875 16 -0.46296456 -1.0989397 0.34473684 0.4121614 1.0 5603 tags=63%, list=37%, signal=99% NEGATIVE REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042130 NEGATIVE REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042130 23 -0.4155484 -1.098565 0.31232092 0.41253728 1.0 2135 tags=30%, list=14%, signal=35% PROTEIN POLYMERIZATION%GOBP%GO:0051258 PROTEIN POLYMERIZATION%GOBP%GO:0051258 54 -0.34530726 -1.0979269 0.24894515 0.41337845 1.0 2257 tags=20%, list=15%, signal=24% VACUOLE ORGANIZATION%GOBP%GO:0007033 VACUOLE ORGANIZATION%GOBP%GO:0007033 87 -0.30972308 -1.0974023 0.21052632 0.4140955 1.0 3858 tags=24%, list=25%, signal=32% BIOCARTA_PML_PATHWAY%MSIGDB_C2%BIOCARTA_PML_PATHWAY BIOCARTA_PML_PATHWAY%MSIGDB_C2%BIOCARTA_PML_PATHWAY 16 -0.44601423 -1.0973846 0.32125604 0.41383806 1.0 474 tags=13%, list=3%, signal=13% T CELL DIFFERENTIATION%GOBP%GO:0030217 T CELL DIFFERENTIATION%GOBP%GO:0030217 52 -0.35578832 -1.0970814 0.27309236 0.41405126 1.0 2606 tags=40%, list=17%, signal=49% REGULATION OF B CELL ACTIVATION%GOBP%GO:0050864 REGULATION OF B CELL ACTIVATION%GOBP%GO:0050864 55 -0.34461197 -1.0966929 0.26996198 0.41451293 1.0 1826 tags=29%, list=12%, signal=33% FATTY ACID BIOSYNTHETIC PROCESS%GOBP%GO:0006633 FATTY ACID BIOSYNTHETIC PROCESS%GOBP%GO:0006633 50 -0.34491912 -1.0944353 0.26415095 0.41830802 1.0 1949 tags=26%, list=13%, signal=30% REGULATION OF TELOMERASE%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%REGULATION OF TELOMERASE REGULATION OF TELOMERASE%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%REGULATION OF TELOMERASE 64 -0.32963747 -1.0942978 0.23255815 0.41826224 1.0 3209 tags=31%, list=21%, signal=39% REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903311 REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903311 85 -0.3240459 -1.0927409 0.23913044 0.42080292 1.0 4235 tags=26%, list=28%, signal=36% GLYCEROPHOSPHOLIPID BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%1483206 GLYCEROPHOSPHOLIPID BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%1483206 112 -0.30082935 -1.0926102 0.22 0.42076135 1.0 1768 tags=17%, list=12%, signal=19% PROTEIN DEACETYLATION%GOBP%GO:0006476 PROTEIN DEACETYLATION%GOBP%GO:0006476 35 -0.3699949 -1.0894879 0.2880259 0.42631102 1.0 4300 tags=29%, list=28%, signal=40% DNA DOUBLE STRAND BREAK RESPONSE%REACTOME%R-HSA-5693606.1 DNA DOUBLE STRAND BREAK RESPONSE%REACTOME%R-HSA-5693606.1 59 -0.33870196 -1.0892259 0.26996198 0.42651358 1.0 3736 tags=36%, list=25%, signal=47% PROTEIN HOMOTETRAMERIZATION%GOBP%GO:0051289 PROTEIN HOMOTETRAMERIZATION%GOBP%GO:0051289 46 -0.35009477 -1.0885433 0.2789855 0.4274722 1.0 2088 tags=33%, list=14%, signal=38% INTERFERON-GAMMA SIGNALING PATHWAY%PANTHER PATHWAY%P00035 INTERFERON-GAMMA SIGNALING PATHWAY%PANTHER PATHWAY%P00035 27 -0.39855066 -1.0879977 0.31686047 0.4281894 1.0 507 tags=15%, list=3%, signal=15% ORGANELLE DISASSEMBLY%GOBP%GO:1903008 ORGANELLE DISASSEMBLY%GOBP%GO:1903008 48 -0.3487914 -1.0873843 0.31578946 0.4290449 1.0 3745 tags=25%, list=25%, signal=33% CELLULAR RESPONSE TO ALKALOID%GOBP%GO:0071312 CELLULAR RESPONSE TO ALKALOID%GOBP%GO:0071312 16 -0.45322838 -1.0871148 0.34536082 0.42923364 1.0 2881 tags=38%, list=19%, signal=46% ALCOHOL CATABOLIC PROCESS%GOBP%GO:0046164 ALCOHOL CATABOLIC PROCESS%GOBP%GO:0046164 22 -0.41034088 -1.086819 0.3472222 0.42949587 1.0 3574 tags=41%, list=23%, signal=53% HEXOSE UPTAKE%REACTOME DATABASE ID RELEASE 60%189200 HEXOSE UPTAKE%REACTOME DATABASE ID RELEASE 60%189200 39 -0.3656221 -1.0862466 0.3118644 0.43031505 1.0 4293 tags=46%, list=28%, signal=64% PEROXISOMAL TRANSPORT%GOBP%GO:0043574 PEROXISOMAL TRANSPORT%GOBP%GO:0043574 17 -0.45925313 -1.084987 0.36144578 0.43231606 1.0 5275 tags=53%, list=35%, signal=81% TRICARBOXYLIC ACID METABOLIC PROCESS%GOBP%GO:0072350 TRICARBOXYLIC ACID METABOLIC PROCESS%GOBP%GO:0072350 35 -0.3735581 -1.0849723 0.3164557 0.43204507 1.0 4758 tags=60%, list=31%, signal=87% REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0090199 REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA%GOBP%GO:0090199 36 -0.36101648 -1.0846064 0.31578946 0.43241906 1.0 3345 tags=36%, list=22%, signal=46% REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY%GOBP%GO:2000116 REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY%GOBP%GO:2000116 151 -0.29029915 -1.0842657 0.22772278 0.43275613 1.0 1661 tags=17%, list=11%, signal=18% POSITIVE REGULATION OF TELOMERASE ACTIVITY%GOBP%GO:0051973 POSITIVE REGULATION OF TELOMERASE ACTIVITY%GOBP%GO:0051973 35 -0.37323675 -1.0840017 0.33431953 0.43297222 1.0 3544 tags=34%, list=23%, signal=45% REGULATION OF NUCLEAR DIVISION%GOBP%GO:0051783 REGULATION OF NUCLEAR DIVISION%GOBP%GO:0051783 115 -0.29997015 -1.0834589 0.22543353 0.43368456 1.0 1817 tags=24%, list=12%, signal=27% REGULATION OF RNA SPLICING%GOBP%GO:0043484 REGULATION OF RNA SPLICING%GOBP%GO:0043484 64 -0.3332605 -1.0832006 0.2857143 0.43382862 1.0 3824 tags=28%, list=25%, signal=37% CDP-DIACYLGLYCEROL BIOSYNTHESIS I%HUMANCYC%PWY-5667 CDP-DIACYLGLYCEROL BIOSYNTHESIS I%HUMANCYC%PWY-5667 18 -0.43224293 -1.0825281 0.37373737 0.4347852 1.0 1648 tags=17%, list=11%, signal=19% PROTEIN DESTABILIZATION%GOBP%GO:0031648 PROTEIN DESTABILIZATION%GOBP%GO:0031648 26 -0.40279436 -1.0815387 0.33846155 0.4364417 1.0 532 tags=8%, list=3%, signal=8% DEFENSE RESPONSE TO GRAM-NEGATIVE BACTERIUM%GOBP%GO:0050829 DEFENSE RESPONSE TO GRAM-NEGATIVE BACTERIUM%GOBP%GO:0050829 22 -0.4182795 -1.0813669 0.34550563 0.4364869 1.0 2140 tags=45%, list=14%, signal=53% FATTY ACID DERIVATIVE BIOSYNTHETIC PROCESS%GOBP%GO:1901570 FATTY ACID DERIVATIVE BIOSYNTHETIC PROCESS%GOBP%GO:1901570 61 -0.32575336 -1.0793084 0.28294572 0.44014052 1.0 2794 tags=31%, list=18%, signal=38% INSULIN RECEPTOR RECYCLING%REACTOME DATABASE ID RELEASE 60%77387 INSULIN RECEPTOR RECYCLING%REACTOME DATABASE ID RELEASE 60%77387 22 -0.41240582 -1.0792192 0.33527696 0.44000033 1.0 6644 tags=73%, list=44%, signal=129% TISSUE HOMEOSTASIS%GOBP%GO:0001894 TISSUE HOMEOSTASIS%GOBP%GO:0001894 62 -0.3311843 -1.07907 0.2918455 0.4399792 1.0 2836 tags=23%, list=19%, signal=28% TRANSFERRIN ENDOCYTOSIS AND RECYCLING%REACTOME DATABASE ID RELEASE 60%917977 TRANSFERRIN ENDOCYTOSIS AND RECYCLING%REACTOME DATABASE ID RELEASE 60%917977 28 -0.3927893 -1.0780336 0.32537314 0.44168904 1.0 6785 tags=68%, list=45%, signal=122% NUCLEUS ORGANIZATION%GOBP%GO:0006997 NUCLEUS ORGANIZATION%GOBP%GO:0006997 98 -0.3051174 -1.0775838 0.27272728 0.44225898 1.0 4293 tags=37%, list=28%, signal=51% GLYCOGEN CATABOLIC PROCESS%GOBP%GO:0005980 GLYCOGEN CATABOLIC PROCESS%GOBP%GO:0005980 15 -0.45212016 -1.0773842 0.37470168 0.44233152 1.0 703 tags=13%, list=5%, signal=14% WATER-SOLUBLE VITAMIN METABOLIC PROCESS%GOBP%GO:0006767 WATER-SOLUBLE VITAMIN METABOLIC PROCESS%GOBP%GO:0006767 72 -0.3154085 -1.077341 0.24896266 0.4421141 1.0 2654 tags=28%, list=17%, signal=33% SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE%GOBP%GO:0042770 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE%GOBP%GO:0042770 87 -0.31142753 -1.0765699 0.2717949 0.44329154 1.0 4807 tags=47%, list=32%, signal=69% LDL CLEARANCE%REACTOME%R-HSA-8964038.1 LDL CLEARANCE%REACTOME%R-HSA-8964038.1 17 -0.44383377 -1.0764288 0.34 0.44322857 1.0 3990 tags=41%, list=26%, signal=56% G2 DNA DAMAGE CHECKPOINT%GOBP%GO:0031572 G2 DNA DAMAGE CHECKPOINT%GOBP%GO:0031572 29 -0.38943312 -1.0761882 0.32119206 0.44338927 1.0 2804 tags=31%, list=18%, signal=38% CCR9%IOB%CCR9 CCR9%IOB%CCR9 17 -0.44809052 -1.0752585 0.36097562 0.44490004 1.0 531 tags=12%, list=3%, signal=12% REGULATION OF MITOTIC NUCLEAR DIVISION%GOBP%GO:0007088 REGULATION OF MITOTIC NUCLEAR DIVISION%GOBP%GO:0007088 113 -0.30275288 -1.0748352 0.2585034 0.44545376 1.0 1817 tags=25%, list=12%, signal=28% POSITIVE REGULATION OF T CELL DIFFERENTIATION%GOBP%GO:0045582 POSITIVE REGULATION OF T CELL DIFFERENTIATION%GOBP%GO:0045582 38 -0.36131263 -1.074672 0.34527686 0.44546655 1.0 2140 tags=37%, list=14%, signal=43% MULTIVESICULAR BODY ASSEMBLY%GOBP%GO:0036258 MULTIVESICULAR BODY ASSEMBLY%GOBP%GO:0036258 27 -0.39170122 -1.0731479 0.33152175 0.44804272 1.0 5115 tags=44%, list=34%, signal=67% RESPONSE TO HYPOXIA%GOBP%GO:0001666 RESPONSE TO HYPOXIA%GOBP%GO:0001666 168 -0.2803094 -1.0730891 0.22222222 0.44783562 1.0 1682 tags=17%, list=11%, signal=19% RESPONSE TO LIPOPOLYSACCHARIDE%GOBP%GO:0032496 RESPONSE TO LIPOPOLYSACCHARIDE%GOBP%GO:0032496 126 -0.29577476 -1.0722677 0.22516556 0.44916153 1.0 1607 tags=16%, list=11%, signal=18% HEXOSE BIOSYNTHETIC PROCESS%GOBP%GO:0019319 HEXOSE BIOSYNTHETIC PROCESS%GOBP%GO:0019319 37 -0.36818334 -1.0716335 0.3245033 0.4500684 1.0 3546 tags=32%, list=23%, signal=42% MULTIVESICULAR BODY SORTING PATHWAY%GOBP%GO:0071985 MULTIVESICULAR BODY SORTING PATHWAY%GOBP%GO:0071985 20 -0.42274833 -1.071384 0.38726792 0.45025942 1.0 4126 tags=40%, list=27%, signal=55% SIGNAL TRANSDUCTION INVOLVED IN CELL CYCLE CHECKPOINT%GOBP%GO:0072395 SIGNAL TRANSDUCTION INVOLVED IN CELL CYCLE CHECKPOINT%GOBP%GO:0072395 62 -0.32819834 -1.0710433 0.31578946 0.45059666 1.0 3379 tags=34%, list=22%, signal=43% PHOSPHATIDYLGLYCEROL BIOSYNTHESIS II (NON-PLASTIDIC)%HUMANCYC%PWY4FS-8 PHOSPHATIDYLGLYCEROL BIOSYNTHESIS II (NON-PLASTIDIC)%HUMANCYC%PWY4FS-8 19 -0.4272144 -1.069825 0.37336814 0.4526749 1.0 1648 tags=16%, list=11%, signal=18% ASPARTATE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009066 ASPARTATE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009066 42 -0.35117692 -1.0696932 0.33203125 0.45260328 1.0 3829 tags=43%, list=25%, signal=57% PURINE NUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0006164 PURINE NUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0006164 77 -0.31242725 -1.0696347 0.29326922 0.45241728 1.0 2721 tags=34%, list=18%, signal=41% REGULATION OF LYMPHOCYTE MIGRATION%GOBP%GO:2000401 REGULATION OF LYMPHOCYTE MIGRATION%GOBP%GO:2000401 32 -0.37042087 -1.0676548 0.3386076 0.45611173 1.0 1819 tags=28%, list=12%, signal=32% RESPONSE TO IONIZING RADIATION%GOBP%GO:0010212 RESPONSE TO IONIZING RADIATION%GOBP%GO:0010212 83 -0.30779508 -1.0673981 0.26984128 0.4562748 1.0 4956 tags=42%, list=33%, signal=62% DISEASES OF METABOLISM%REACTOME%R-HSA-5668914.1 DISEASES OF METABOLISM%REACTOME%R-HSA-5668914.1 37 -0.36296323 -1.06731 0.30136988 0.45612556 1.0 4440 tags=46%, list=29%, signal=65% GLUCAN CATABOLIC PROCESS%GOBP%GO:0009251 GLUCAN CATABOLIC PROCESS%GOBP%GO:0009251 15 -0.45212016 -1.0660441 0.37435898 0.45828965 1.0 703 tags=13%, list=5%, signal=14% MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM%GOBP%GO:0035821 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM%GOBP%GO:0035821 88 -0.31172916 -1.0654384 0.27184466 0.4591722 1.0 3737 tags=31%, list=25%, signal=40% HISTONE H2A UBIQUITINATION%GOBP%GO:0033522 HISTONE H2A UBIQUITINATION%GOBP%GO:0033522 16 -0.4448773 -1.0650797 0.3872549 0.45955488 1.0 2209 tags=25%, list=15%, signal=29% INTRAFLAGELLAR TRANSPORT%REACTOME%R-HSA-5620924.3 INTRAFLAGELLAR TRANSPORT%REACTOME%R-HSA-5620924.3 37 -0.35400364 -1.0648394 0.34343433 0.45969772 1.0 1922 tags=19%, list=13%, signal=22% SA_MMP_CYTOKINE_CONNECTION%MSIGDB_C2%SA_MMP_CYTOKINE_CONNECTION SA_MMP_CYTOKINE_CONNECTION%MSIGDB_C2%SA_MMP_CYTOKINE_CONNECTION 15 -0.4422095 -1.0643891 0.38190955 0.46028852 1.0 397 tags=13%, list=3%, signal=14% HISTONE ACETYLATION%GOBP%GO:0016573 HISTONE ACETYLATION%GOBP%GO:0016573 64 -0.3230597 -1.0636972 0.29166666 0.46130094 1.0 4265 tags=33%, list=28%, signal=45% REGULATION OF CELLULAR PH%GOBP%GO:0030641 REGULATION OF CELLULAR PH%GOBP%GO:0030641 63 -0.31836 -1.063481 0.3375 0.46141264 1.0 4223 tags=30%, list=28%, signal=42% POLYSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0000272 POLYSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0000272 15 -0.45212016 -1.0631077 0.3871795 0.46186978 1.0 703 tags=13%, list=5%, signal=14% NEGATIVE REGULATION OF EXOCYTOSIS%GOBP%GO:0045920 NEGATIVE REGULATION OF EXOCYTOSIS%GOBP%GO:0045920 17 -0.4466811 -1.0599036 0.39042822 0.46785203 1.0 1803 tags=35%, list=12%, signal=40% CELLULAR RESPONSE TO STARVATION%GOBP%GO:0009267 CELLULAR RESPONSE TO STARVATION%GOBP%GO:0009267 88 -0.304765 -1.0598385 0.30769232 0.46766973 1.0 3762 tags=27%, list=25%, signal=36% CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0035710 CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:0035710 19 -0.41569707 -1.0588021 0.38395417 0.4693738 1.0 2461 tags=42%, list=16%, signal=50% FATTY-ACYL-COA BIOSYNTHETIC PROCESS%GOBP%GO:0046949 FATTY-ACYL-COA BIOSYNTHETIC PROCESS%GOBP%GO:0046949 23 -0.40195143 -1.0584521 0.38352272 0.46977067 1.0 1392 tags=22%, list=9%, signal=24% NEGATIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903556 NEGATIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION%GOBP%GO:1903556 23 -0.41108724 -1.0580086 0.37260273 0.47035158 1.0 3154 tags=39%, list=21%, signal=49% INTERNAL PEPTIDYL-LYSINE ACETYLATION%GOBP%GO:0018393 INTERNAL PEPTIDYL-LYSINE ACETYLATION%GOBP%GO:0018393 64 -0.3230597 -1.05797 0.31854838 0.4701083 1.0 4265 tags=33%, list=28%, signal=45% REGULATION OF MITOPHAGY%GOBP%GO:1903146 REGULATION OF MITOPHAGY%GOBP%GO:1903146 39 -0.35210025 -1.0566586 0.35069445 0.47247967 1.0 3711 tags=31%, list=24%, signal=41% REGULATION OF INTRACELLULAR PH%GOBP%GO:0051453 REGULATION OF INTRACELLULAR PH%GOBP%GO:0051453 63 -0.31836 -1.0562621 0.30088496 0.4729112 1.0 4223 tags=30%, list=28%, signal=42% CERAMIDE METABOLIC PROCESS%GOBP%GO:0006672 CERAMIDE METABOLIC PROCESS%GOBP%GO:0006672 36 -0.3565164 -1.0560952 0.3458904 0.47291672 1.0 2466 tags=25%, list=16%, signal=30% IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION%REACTOME%R-HSA-975163.1 IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION%REACTOME%R-HSA-975163.1 16 -0.44454616 -1.0560808 0.4234694 0.4726297 1.0 2247 tags=19%, list=15%, signal=22% HALLMARK_HEME_METABOLISM%MSIGDB_C2%HALLMARK_HEME_METABOLISM HALLMARK_HEME_METABOLISM%MSIGDB_C2%HALLMARK_HEME_METABOLISM 172 -0.2758275 -1.0558093 0.2952381 0.47285423 1.0 4888 tags=37%, list=32%, signal=54% N-TERMINAL PROTEIN AMINO ACID MODIFICATION%GOBP%GO:0031365 N-TERMINAL PROTEIN AMINO ACID MODIFICATION%GOBP%GO:0031365 19 -0.41844702 -1.0553252 0.3604336 0.47353283 1.0 5007 tags=42%, list=33%, signal=63% GAMETE GENERATION%GOBP%GO:0007276 GAMETE GENERATION%GOBP%GO:0007276 150 -0.278765 -1.0545039 0.28 0.4748801 1.0 3482 tags=27%, list=23%, signal=35% REGULATION OF ANTIGEN PROCESSING AND PRESENTATION%GOBP%GO:0002577 REGULATION OF ANTIGEN PROCESSING AND PRESENTATION%GOBP%GO:0002577 15 -0.43800822 -1.0538596 0.37592137 0.475913 1.0 849 tags=33%, list=6%, signal=35% NEGATIVE REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0032897 NEGATIVE REGULATION OF VIRAL TRANSCRIPTION%GOBP%GO:0032897 21 -0.40876034 -1.0523493 0.3648294 0.4785877 1.0 4125 tags=48%, list=27%, signal=65% SPERM MOTILITY%GOBP%GO:0097722 SPERM MOTILITY%GOBP%GO:0097722 18 -0.44208622 -1.0520811 0.39753085 0.47886238 1.0 5224 tags=39%, list=34%, signal=59% MODULATION BY SYMBIONT OF HOST CELLULAR PROCESS%GOBP%GO:0044068 MODULATION BY SYMBIONT OF HOST CELLULAR PROCESS%GOBP%GO:0044068 23 -0.40721652 -1.0520433 0.352459 0.47862563 1.0 5080 tags=39%, list=33%, signal=59% FATTY ACID DERIVATIVE METABOLIC PROCESS%GOBP%GO:1901568 FATTY ACID DERIVATIVE METABOLIC PROCESS%GOBP%GO:1901568 101 -0.29687855 -1.051826 0.30674848 0.47876352 1.0 1470 tags=16%, list=10%, signal=17% REGULATION OF TRIGLYCERIDE METABOLIC PROCESS%GOBP%GO:0090207 REGULATION OF TRIGLYCERIDE METABOLIC PROCESS%GOBP%GO:0090207 17 -0.43224484 -1.0512255 0.3857868 0.479651 1.0 739 tags=12%, list=5%, signal=12% HALLMARK_UNFOLDED_PROTEIN_RESPONSE%MSIGDB_C2%HALLMARK_UNFOLDED_PROTEIN_RESPONSE HALLMARK_UNFOLDED_PROTEIN_RESPONSE%MSIGDB_C2%HALLMARK_UNFOLDED_PROTEIN_RESPONSE 111 -0.2899408 -1.0493956 0.27672955 0.4830238 1.0 2779 tags=22%, list=18%, signal=26% PHOTORECEPTOR CELL MAINTENANCE%GOBP%GO:0045494 PHOTORECEPTOR CELL MAINTENANCE%GOBP%GO:0045494 16 -0.43729836 -1.0489354 0.38961038 0.48362136 1.0 1798 tags=19%, list=12%, signal=21% AUTOPHAGOSOME MATURATION%GOBP%GO:0097352 AUTOPHAGOSOME MATURATION%GOBP%GO:0097352 23 -0.39376932 -1.0481501 0.36235955 0.48486444 1.0 3692 tags=35%, list=24%, signal=46% NEGATIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032211 NEGATIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERASE%GOBP%GO:0032211 18 -0.43878552 -1.0468978 0.42424244 0.48713356 1.0 1156 tags=22%, list=8%, signal=24% BIOCARTA_TCR_PATHWAY%MSIGDB_C2%BIOCARTA_TCR_PATHWAY BIOCARTA_TCR_PATHWAY%MSIGDB_C2%BIOCARTA_TCR_PATHWAY 44 -0.34146824 -1.0460501 0.37651822 0.48855323 1.0 1507 tags=23%, list=10%, signal=25% TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX%REACTOME%R-HSA-937072.1 TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX%REACTOME%R-HSA-937072.1 16 -0.44454616 -1.0459559 0.40625 0.4884109 1.0 2247 tags=19%, list=15%, signal=22% RESPONSE TO DECREASED OXYGEN LEVELS%GOBP%GO:0036293 RESPONSE TO DECREASED OXYGEN LEVELS%GOBP%GO:0036293 171 -0.27703124 -1.0457025 0.31578946 0.48860136 1.0 1682 tags=17%, list=11%, signal=19% CELLULAR POLYSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0044247 CELLULAR POLYSACCHARIDE CATABOLIC PROCESS%GOBP%GO:0044247 15 -0.45212016 -1.045356 0.40206185 0.48899496 1.0 703 tags=13%, list=5%, signal=14% NLS-BEARING PROTEIN IMPORT INTO NUCLEUS%GOBP%GO:0006607 NLS-BEARING PROTEIN IMPORT INTO NUCLEUS%GOBP%GO:0006607 21 -0.40503132 -1.0453248 0.37958115 0.48872775 1.0 3032 tags=29%, list=20%, signal=36% BIOCARTA_INFLAM_PATHWAY%MSIGDB_C2%BIOCARTA_INFLAM_PATHWAY BIOCARTA_INFLAM_PATHWAY%MSIGDB_C2%BIOCARTA_INFLAM_PATHWAY 16 -0.44804502 -1.0448914 0.39722222 0.48927724 1.0 397 tags=31%, list=3%, signal=32% PID_BCR_5PATHWAY%MSIGDB_C2%PID_BCR_5PATHWAY PID_BCR_5PATHWAY%MSIGDB_C2%PID_BCR_5PATHWAY 65 -0.31336403 -1.0447817 0.3697479 0.48916993 1.0 2167 tags=22%, list=14%, signal=25% TRANSITION METAL ION HOMEOSTASIS%GOBP%GO:0055076 TRANSITION METAL ION HOMEOSTASIS%GOBP%GO:0055076 78 -0.3113956 -1.0444689 0.3041237 0.48947704 1.0 2560 tags=23%, list=17%, signal=28% RIBOSE PHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0046390 RIBOSE PHOSPHATE BIOSYNTHETIC PROCESS%GOBP%GO:0046390 76 -0.30656797 -1.0444673 0.30985916 0.4891628 1.0 2721 tags=33%, list=18%, signal=40% OXIDATIVE STRESS INDUCED SENESCENCE%REACTOME DATABASE ID RELEASE 60%2559580 OXIDATIVE STRESS INDUCED SENESCENCE%REACTOME DATABASE ID RELEASE 60%2559580 90 -0.29392445 -1.0442007 0.37566137 0.4893757 1.0 3326 tags=32%, list=22%, signal=41% LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002285 LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002285 45 -0.33125216 -1.044173 0.34642857 0.48910987 1.0 2970 tags=29%, list=20%, signal=36% BCR SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BCR SIGNALING PATHWAY BCR SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BCR SIGNALING PATHWAY 66 -0.3123706 -1.0430444 0.32608697 0.49105 1.0 2167 tags=21%, list=14%, signal=25% PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006612 PROTEIN TARGETING TO MEMBRANE%GOBP%GO:0006612 144 -0.28016463 -1.0424151 0.29787233 0.49200547 1.0 5490 tags=46%, list=36%, signal=71% TRANS-GOLGI NETWORK VESICLE BUDDING%REACTOME%R-HSA-199992.2 TRANS-GOLGI NETWORK VESICLE BUDDING%REACTOME%R-HSA-199992.2 69 -0.30845803 -1.0406183 0.35526314 0.49540812 1.0 2974 tags=23%, list=20%, signal=29% BIOCARTA_IL2_PATHWAY%MSIGDB_C2%BIOCARTA_IL2_PATHWAY BIOCARTA_IL2_PATHWAY%MSIGDB_C2%BIOCARTA_IL2_PATHWAY 21 -0.40142605 -1.0399688 0.4005682 0.4963858 1.0 2240 tags=29%, list=15%, signal=33% REGULATION OF TELOMERE CAPPING%GOBP%GO:1904353 REGULATION OF TELOMERE CAPPING%GOBP%GO:1904353 24 -0.395688 -1.039894 0.3957219 0.4961909 1.0 625 tags=13%, list=4%, signal=13% REGULATION OF T CELL CYTOKINE PRODUCTION%GOBP%GO:0002724 REGULATION OF T CELL CYTOKINE PRODUCTION%GOBP%GO:0002724 16 -0.43284214 -1.0398773 0.43513513 0.49589607 1.0 2135 tags=25%, list=14%, signal=29% DE NOVO PURINE BIOSYNTHESIS%PANTHER PATHWAY%P02738 DE NOVO PURINE BIOSYNTHESIS%PANTHER PATHWAY%P02738 24 -0.39745107 -1.0393687 0.40502793 0.4966561 1.0 4055 tags=50%, list=27%, signal=68% BIOCARTA_IL7_PATHWAY%MSIGDB_C2%BIOCARTA_IL7_PATHWAY BIOCARTA_IL7_PATHWAY%MSIGDB_C2%BIOCARTA_IL7_PATHWAY 17 -0.4229527 -1.0374707 0.38157895 0.5002148 1.0 1125 tags=18%, list=7%, signal=19% PID_CD40_PATHWAY%MSIGDB_C2%PID_CD40_PATHWAY PID_CD40_PATHWAY%MSIGDB_C2%PID_CD40_PATHWAY 27 -0.38573214 -1.0374156 0.38690478 0.49998105 1.0 3449 tags=33%, list=23%, signal=43% RESPONSE TO OXYGEN LEVELS%GOBP%GO:0070482 RESPONSE TO OXYGEN LEVELS%GOBP%GO:0070482 175 -0.27260002 -1.0369991 0.34042552 0.50057924 1.0 1682 tags=17%, list=11%, signal=18% PROTEIN K63-LINKED UBIQUITINATION%GOBP%GO:0070534 PROTEIN K63-LINKED UBIQUITINATION%GOBP%GO:0070534 34 -0.35741773 -1.0367748 0.39308175 0.50070494 1.0 4315 tags=41%, list=28%, signal=57% REGULATION OF T CELL MIGRATION%GOBP%GO:2000404 REGULATION OF T CELL MIGRATION%GOBP%GO:2000404 22 -0.39884797 -1.036601 0.42777777 0.5007085 1.0 2570 tags=45%, list=17%, signal=55% CELLULAR RESPONSE TO MISFOLDED PROTEIN%GOBP%GO:0071218 CELLULAR RESPONSE TO MISFOLDED PROTEIN%GOBP%GO:0071218 18 -0.4257296 -1.0361495 0.42673522 0.50136906 1.0 4315 tags=39%, list=28%, signal=54% HALLMARK_UV_RESPONSE_UP%MSIGDB_C2%HALLMARK_UV_RESPONSE_UP HALLMARK_UV_RESPONSE_UP%MSIGDB_C2%HALLMARK_UV_RESPONSE_UP 149 -0.27990934 -1.0357398 0.32231405 0.5018994 1.0 3064 tags=30%, list=20%, signal=37% GLYCOGEN BREAKDOWN (GLYCOGENOLYSIS)%REACTOME DATABASE ID RELEASE 60%70221 GLYCOGEN BREAKDOWN (GLYCOGENOLYSIS)%REACTOME DATABASE ID RELEASE 60%70221 17 -0.41826484 -1.0355966 0.42635658 0.5018548 1.0 703 tags=12%, list=5%, signal=12% BCR%NETPATH%BCR BCR%NETPATH%BCR 157 -0.27143225 -1.0348368 0.32743362 0.5030982 1.0 2167 tags=21%, list=14%, signal=24% RIBONUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009260 RIBONUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009260 74 -0.30861947 -1.0346787 0.36574075 0.5030936 1.0 2721 tags=34%, list=18%, signal=41% REGULATION OF CELLULAR RESPONSE TO HEAT%GOBP%GO:1900034 REGULATION OF CELLULAR RESPONSE TO HEAT%GOBP%GO:1900034 72 -0.31198883 -1.0346075 0.3611111 0.50292265 1.0 4439 tags=35%, list=29%, signal=49% REGULATION OF TP53 ACTIVITY%REACTOME%R-HSA-5633007.2 REGULATION OF TP53 ACTIVITY%REACTOME%R-HSA-5633007.2 150 -0.2710821 -1.0308573 0.3931624 0.51054996 1.0 4440 tags=36%, list=29%, signal=50% POSITIVE REGULATION OF NEUTROPHIL CHEMOTAXIS%GOBP%GO:0090023 POSITIVE REGULATION OF NEUTROPHIL CHEMOTAXIS%GOBP%GO:0090023 19 -0.4100019 -1.0299382 0.44179896 0.5122044 1.0 1819 tags=21%, list=12%, signal=24% POSITIVE REGULATION OF PEPTIDYL-THREONINE PHOSPHORYLATION%GOBP%GO:0010800 POSITIVE REGULATION OF PEPTIDYL-THREONINE PHOSPHORYLATION%GOBP%GO:0010800 17 -0.42315418 -1.0289518 0.42171717 0.5139279 1.0 1825 tags=24%, list=12%, signal=27% POSITIVE REGULATION OF LYMPHOCYTE MIGRATION%GOBP%GO:2000403 POSITIVE REGULATION OF LYMPHOCYTE MIGRATION%GOBP%GO:2000403 22 -0.3870662 -1.0287006 0.3814714 0.5140954 1.0 2570 tags=36%, list=17%, signal=44% HEXOSE CATABOLIC PROCESS%GOBP%GO:0019320 HEXOSE CATABOLIC PROCESS%GOBP%GO:0019320 40 -0.34865543 -1.0281457 0.38487974 0.5148923 1.0 4344 tags=33%, list=29%, signal=45% TOLL LIKE RECEPTOR 7 8 (TLR7 8) CASCADE%REACTOME DATABASE ID RELEASE 60%168181 TOLL LIKE RECEPTOR 7 8 (TLR7 8) CASCADE%REACTOME DATABASE ID RELEASE 60%168181 93 -0.28889164 -1.0279918 0.37055838 0.51488787 1.0 2571 tags=20%, list=17%, signal=24% POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE%GOBP%GO:0002702 POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE%GOBP%GO:0002702 37 -0.35383853 -1.0269812 0.38255033 0.5166942 1.0 1611 tags=22%, list=11%, signal=24% GLUTATHIONE DERIVATIVE BIOSYNTHETIC PROCESS%GOBP%GO:1901687 GLUTATHIONE DERIVATIVE BIOSYNTHETIC PROCESS%GOBP%GO:1901687 19 -0.40416956 -1.0269341 0.42933333 0.5164569 1.0 2699 tags=42%, list=18%, signal=51% CILIUM ASSEMBLY%REACTOME DATABASE ID RELEASE 60%5617833 CILIUM ASSEMBLY%REACTOME DATABASE ID RELEASE 60%5617833 165 -0.27059376 -1.0249887 0.37037036 0.52025616 1.0 1922 tags=16%, list=13%, signal=19% CLATHRIN DERIVED VESICLE BUDDING%REACTOME%R-HSA-421837.1 CLATHRIN DERIVED VESICLE BUDDING%REACTOME%R-HSA-421837.1 69 -0.30845803 -1.0247703 0.38207546 0.5204019 1.0 2974 tags=23%, list=20%, signal=29% REGULATION OF INTERLEUKIN-6 PRODUCTION%GOBP%GO:0032675 REGULATION OF INTERLEUKIN-6 PRODUCTION%GOBP%GO:0032675 49 -0.3300817 -1.0245833 0.42975205 0.5205042 1.0 2755 tags=35%, list=18%, signal=42% INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR%GOBP%GO:0072332 INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR%GOBP%GO:0072332 34 -0.34580535 -1.0227612 0.36190477 0.5240392 1.0 1239 tags=15%, list=8%, signal=16% BIOCARTA_CHEMICAL_PATHWAY%MSIGDB_C2%BIOCARTA_CHEMICAL_PATHWAY BIOCARTA_CHEMICAL_PATHWAY%MSIGDB_C2%BIOCARTA_CHEMICAL_PATHWAY 22 -0.38699248 -1.0226858 0.43243244 0.52385145 1.0 3841 tags=36%, list=25%, signal=49% PHOSPHOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0008654 PHOSPHOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0008654 196 -0.26449093 -1.0226562 0.33333334 0.5235763 1.0 1684 tags=14%, list=11%, signal=15% POSITIVE REGULATION OF CELL CYCLE PROCESS%GOBP%GO:0090068 POSITIVE REGULATION OF CELL CYCLE PROCESS%GOBP%GO:0090068 183 -0.2676663 -1.0220193 0.44210526 0.5245874 1.0 2435 tags=25%, list=16%, signal=29% AMYLOID FIBER FORMATION%REACTOME%R-HSA-977225.4 AMYLOID FIBER FORMATION%REACTOME%R-HSA-977225.4 59 -0.32053822 -1.0213448 0.39917696 0.5256764 1.0 3319 tags=34%, list=22%, signal=43% ACTIVATION OF NF-KAPPAB-INDUCING KINASE ACTIVITY%GOBP%GO:0007250 ACTIVATION OF NF-KAPPAB-INDUCING KINASE ACTIVITY%GOBP%GO:0007250 16 -0.42418754 -1.019763 0.41943735 0.5287119 1.0 2124 tags=19%, list=14%, signal=22% CD40 CD40L SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CD40 CD40L SIGNALING CD40 CD40L SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CD40 CD40L SIGNALING 32 -0.35834348 -1.0188609 0.42682928 0.53031725 1.0 3449 tags=31%, list=23%, signal=40% VACUOLE FUSION%GOBP%GO:0097576 VACUOLE FUSION%GOBP%GO:0097576 24 -0.39210945 -1.018578 0.41666666 0.5305755 1.0 3692 tags=33%, list=24%, signal=44% ERAD PATHWAY%GOBP%GO:0036503 ERAD PATHWAY%GOBP%GO:0036503 74 -0.3071091 -1.017956 0.41708544 0.531586 1.0 4420 tags=26%, list=29%, signal=36% GLYCOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0009247 GLYCOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0009247 44 -0.32983193 -1.0173553 0.4040404 0.5324909 1.0 2993 tags=23%, list=20%, signal=28% OXIDOREDUCTION COENZYME METABOLIC PROCESS%GOBP%GO:0006733 OXIDOREDUCTION COENZYME METABOLIC PROCESS%GOBP%GO:0006733 84 -0.29297295 -1.0157613 0.3888889 0.5354555 1.0 3546 tags=31%, list=23%, signal=40% POSITIVE REGULATION OF T CELL MIGRATION%GOBP%GO:2000406 POSITIVE REGULATION OF T CELL MIGRATION%GOBP%GO:2000406 18 -0.41482258 -1.0157443 0.41952506 0.53515625 1.0 2570 tags=44%, list=17%, signal=53% REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032680 REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032680 53 -0.31058073 -1.0151572 0.38059703 0.5360772 1.0 2570 tags=30%, list=17%, signal=36% GLUTAMINE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009064 GLUTAMINE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009064 32 -0.3497176 -1.0147885 0.42987806 0.5365512 1.0 374 tags=9%, list=2%, signal=10% EXTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:0097191 EXTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:0097191 57 -0.3110992 -1.0141702 0.42857143 0.5375197 1.0 1365 tags=18%, list=9%, signal=19% MYD88 DEPENDENT CASCADE INITIATED ON ENDOSOME%REACTOME DATABASE ID RELEASE 60%975155 MYD88 DEPENDENT CASCADE INITIATED ON ENDOSOME%REACTOME DATABASE ID RELEASE 60%975155 93 -0.28889164 -1.0138303 0.3809524 0.53795433 1.0 2571 tags=20%, list=17%, signal=24% RECRUITMENT AND ATM-MEDIATED PHOSPHORYLATION OF REPAIR AND SIGNALING PROTEINS AT DNA DOUBLE STRAND BREAKS%REACTOME DATABASE ID RELEASE 60%5693565 RECRUITMENT AND ATM-MEDIATED PHOSPHORYLATION OF REPAIR AND SIGNALING PROTEINS AT DNA DOUBLE STRAND BREAKS%REACTOME DATABASE ID RELEASE 60%5693565 58 -0.31926218 -1.0137465 0.40816328 0.5377941 1.0 3736 tags=34%, list=25%, signal=46% LEUKOCYTE PROLIFERATION%GOBP%GO:0070661 LEUKOCYTE PROLIFERATION%GOBP%GO:0070661 29 -0.36423224 -1.0136864 0.44267517 0.53759414 1.0 3986 tags=41%, list=26%, signal=56% CELLULAR CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0044275 CELLULAR CARBOHYDRATE CATABOLIC PROCESS%GOBP%GO:0044275 19 -0.40077573 -1.0128447 0.44584382 0.5390901 1.0 4973 tags=47%, list=33%, signal=70% REGULATION OF ENDOPLASMIC RETICULUM STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902235 REGULATION OF ENDOPLASMIC RETICULUM STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902235 17 -0.40737468 -1.012688 0.42666668 0.5390649 1.0 1867 tags=35%, list=12%, signal=40% FATTY ACYL-COA BIOSYNTHESIS%REACTOME%R-HSA-75105.6 FATTY ACYL-COA BIOSYNTHESIS%REACTOME%R-HSA-75105.6 26 -0.37394878 -1.0125501 0.4431818 0.53902584 1.0 2025 tags=23%, list=13%, signal=27% REGULATION OF CENTROSOME CYCLE%GOBP%GO:0046605 REGULATION OF CENTROSOME CYCLE%GOBP%GO:0046605 41 -0.34170833 -1.011878 0.41754386 0.5401154 1.0 4946 tags=46%, list=33%, signal=68% ALCOHOL BIOSYNTHETIC PROCESS%GOBP%GO:0046165 ALCOHOL BIOSYNTHETIC PROCESS%GOBP%GO:0046165 49 -0.32749975 -1.0117137 0.40221402 0.5401322 1.0 1482 tags=20%, list=10%, signal=23% P75NTR SIGNALS VIA NF-KB%REACTOME%R-HSA-193639.1 P75NTR SIGNALS VIA NF-KB%REACTOME%R-HSA-193639.1 16 -0.4272283 -1.010605 0.44554454 0.542162 1.0 3183 tags=56%, list=21%, signal=71% TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 60%2151201 TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 60%2151201 51 -0.3255213 -1.0103296 0.42910448 0.5424083 1.0 2251 tags=22%, list=15%, signal=25% VIRAL BUDDING VIA HOST ESCRT COMPLEX%GOBP%GO:0039702 VIRAL BUDDING VIA HOST ESCRT COMPLEX%GOBP%GO:0039702 19 -0.40691948 -1.0087126 0.41145834 0.54561627 1.0 4244 tags=37%, list=28%, signal=51% CELLULAR MODIFIED AMINO ACID METABOLIC PROCESS%GOBP%GO:0006575 CELLULAR MODIFIED AMINO ACID METABOLIC PROCESS%GOBP%GO:0006575 120 -0.28039038 -1.0082027 0.43225807 0.5463359 1.0 2794 tags=25%, list=18%, signal=30% CELLULAR RESPONSE TO HEAT STRESS%REACTOME%R-HSA-3371556.1 CELLULAR RESPONSE TO HEAT STRESS%REACTOME%R-HSA-3371556.1 80 -0.2892424 -1.0075266 0.4631579 0.5474363 1.0 4439 tags=35%, list=29%, signal=49% POSITIVE REGULATION OF CHEMOKINE PRODUCTION%GOBP%GO:0032722 POSITIVE REGULATION OF CHEMOKINE PRODUCTION%GOBP%GO:0032722 29 -0.36624548 -1.006685 0.43712574 0.54894656 1.0 773 tags=17%, list=5%, signal=18% GLUTATHIONE DERIVATIVE METABOLIC PROCESS%GOBP%GO:1901685 GLUTATHIONE DERIVATIVE METABOLIC PROCESS%GOBP%GO:1901685 19 -0.40416956 -1.0066748 0.43098593 0.5486217 1.0 2699 tags=42%, list=18%, signal=51% NEGATIVE REGULATION OF PROTEIN KINASE B SIGNALING%GOBP%GO:0051898 NEGATIVE REGULATION OF PROTEIN KINASE B SIGNALING%GOBP%GO:0051898 25 -0.37341827 -1.0064933 0.4200542 0.54866433 1.0 1055 tags=16%, list=7%, signal=17% ACETYL-COA METABOLIC PROCESS%GOBP%GO:0006084 ACETYL-COA METABOLIC PROCESS%GOBP%GO:0006084 15 -0.41920337 -1.0057864 0.44221106 0.54985785 1.0 4758 tags=73%, list=31%, signal=107% MITOCHONDRION LOCALIZATION%GOBP%GO:0051646 MITOCHONDRION LOCALIZATION%GOBP%GO:0051646 20 -0.38518992 -1.0057812 0.45268542 0.54951984 1.0 1425 tags=15%, list=9%, signal=17% ER-NUCLEUS SIGNALING PATHWAY%GOBP%GO:0006984 ER-NUCLEUS SIGNALING PATHWAY%GOBP%GO:0006984 27 -0.36059874 -1.0050527 0.425656 0.55076635 1.0 6040 tags=59%, list=40%, signal=98% POSITIVE REGULATION OF GRANULOCYTE CHEMOTAXIS%GOBP%GO:0071624 POSITIVE REGULATION OF GRANULOCYTE CHEMOTAXIS%GOBP%GO:0071624 21 -0.38886273 -1.0048189 0.42553192 0.5509236 1.0 1819 tags=19%, list=12%, signal=22% SYNTHESIS OF VERY LONG-CHAIN FATTY ACYL-COAS%REACTOME%R-HSA-75876.5 SYNTHESIS OF VERY LONG-CHAIN FATTY ACYL-COAS%REACTOME%R-HSA-75876.5 15 -0.4248888 -1.0046883 0.45524296 0.5508766 1.0 2025 tags=33%, list=13%, signal=38% LYTIC VACUOLE ORGANIZATION%GOBP%GO:0080171 LYTIC VACUOLE ORGANIZATION%GOBP%GO:0080171 36 -0.33977708 -1.004426 0.46308726 0.55110633 1.0 2128 tags=17%, list=14%, signal=19% FOLIC ACID METABOLIC PROCESS%GOBP%GO:0046655 FOLIC ACID METABOLIC PROCESS%GOBP%GO:0046655 17 -0.41983503 -1.0040797 0.4715447 0.551533 1.0 2654 tags=24%, list=17%, signal=28% POSITIVE REGULATION OF CAMP METABOLIC PROCESS%GOBP%GO:0030816 POSITIVE REGULATION OF CAMP METABOLIC PROCESS%GOBP%GO:0030816 48 -0.3250152 -1.0036634 0.4259928 0.55212176 1.0 957 tags=17%, list=6%, signal=18% POSITIVE REGULATION OF NEUTROPHIL MIGRATION%GOBP%GO:1902624 POSITIVE REGULATION OF NEUTROPHIL MIGRATION%GOBP%GO:1902624 20 -0.3946287 -1.0028886 0.45857987 0.5534893 1.0 1819 tags=20%, list=12%, signal=23% MRNA SPLICE SITE SELECTION%GOBP%GO:0006376 MRNA SPLICE SITE SELECTION%GOBP%GO:0006376 15 -0.42571092 -1.0025398 0.46329114 0.5539358 1.0 4260 tags=33%, list=28%, signal=46% REGULATION OF ENDOPLASMIC RETICULUM UNFOLDED PROTEIN RESPONSE%GOBP%GO:1900101 REGULATION OF ENDOPLASMIC RETICULUM UNFOLDED PROTEIN RESPONSE%GOBP%GO:1900101 20 -0.38185483 -1.0022525 0.45833334 0.5542296 1.0 2029 tags=25%, list=13%, signal=29% RNA POLYADENYLATION%GOBP%GO:0043631 RNA POLYADENYLATION%GOBP%GO:0043631 26 -0.3738368 -1.0019728 0.45151514 0.55448884 1.0 3737 tags=35%, list=25%, signal=46% REGULATION OF PHAGOCYTOSIS%GOBP%GO:0050764 REGULATION OF PHAGOCYTOSIS%GOBP%GO:0050764 38 -0.33943117 -1.0003288 0.41042346 0.5578099 1.0 3555 tags=34%, list=23%, signal=45% PURINE RIBONUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009152 PURINE RIBONUCLEOTIDE BIOSYNTHETIC PROCESS%GOBP%GO:0009152 72 -0.30022818 -0.9986623 0.3918919 0.56111187 1.0 2721 tags=33%, list=18%, signal=40% CHROMATIN DISASSEMBLY%GOBP%GO:0031498 CHROMATIN DISASSEMBLY%GOBP%GO:0031498 16 -0.41635373 -0.9982329 0.4730392 0.5617318 1.0 2099 tags=19%, list=14%, signal=22% MRNA POLYADENYLATION%GOBP%GO:0006378 MRNA POLYADENYLATION%GOBP%GO:0006378 24 -0.38048375 -0.99822897 0.45609066 0.5613942 1.0 3737 tags=38%, list=25%, signal=50% REGULATION OF GLYCOPROTEIN BIOSYNTHETIC PROCESS%GOBP%GO:0010559 REGULATION OF GLYCOPROTEIN BIOSYNTHETIC PROCESS%GOBP%GO:0010559 26 -0.36351946 -0.99669987 0.4222874 0.56440794 1.0 2828 tags=31%, list=19%, signal=38% REGULATION OF INTERLEUKIN-1 PRODUCTION%GOBP%GO:0032652 REGULATION OF INTERLEUKIN-1 PRODUCTION%GOBP%GO:0032652 32 -0.34687132 -0.99617726 0.43962848 0.56523657 1.0 1180 tags=19%, list=8%, signal=20% NUCLEOSOME DISASSEMBLY%GOBP%GO:0006337 NUCLEOSOME DISASSEMBLY%GOBP%GO:0006337 16 -0.41635373 -0.9961557 0.48947367 0.56493044 1.0 2099 tags=19%, list=14%, signal=22% TOLL LIKE RECEPTOR 9 (TLR9) CASCADE%REACTOME%R-HSA-168138.1 TOLL LIKE RECEPTOR 9 (TLR9) CASCADE%REACTOME%R-HSA-168138.1 96 -0.2821937 -0.99614924 0.48466256 0.56459165 1.0 2571 tags=20%, list=17%, signal=24% POSITIVE REGULATION OF B CELL ACTIVATION%GOBP%GO:0050871 POSITIVE REGULATION OF B CELL ACTIVATION%GOBP%GO:0050871 34 -0.34897354 -0.9958121 0.4551495 0.56498563 1.0 1692 tags=26%, list=11%, signal=30% CELLULAR MODIFIED AMINO ACID BIOSYNTHETIC PROCESS%GOBP%GO:0042398 CELLULAR MODIFIED AMINO ACID BIOSYNTHETIC PROCESS%GOBP%GO:0042398 27 -0.35551873 -0.9946609 0.44272447 0.56720036 1.0 4488 tags=41%, list=30%, signal=58% MELANOSOME ORGANIZATION%GOBP%GO:0032438 MELANOSOME ORGANIZATION%GOBP%GO:0032438 18 -0.3901916 -0.9942765 0.4375 0.56769806 1.0 2786 tags=28%, list=18%, signal=34% BIOCARTA_TNFR1_PATHWAY%MSIGDB_C2%BIOCARTA_TNFR1_PATHWAY BIOCARTA_TNFR1_PATHWAY%MSIGDB_C2%BIOCARTA_TNFR1_PATHWAY 29 -0.3586284 -0.9937082 0.43452382 0.5685783 1.0 3245 tags=24%, list=21%, signal=31% ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%390471 ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 60%390471 36 -0.34388524 -0.9924788 0.47115386 0.5709536 1.0 5689 tags=61%, list=37%, signal=97% NEGATIVE REGULATION OF NUCLEAR DIVISION%GOBP%GO:0051784 NEGATIVE REGULATION OF NUCLEAR DIVISION%GOBP%GO:0051784 28 -0.3484553 -0.9919692 0.46308726 0.5717935 1.0 1264 tags=25%, list=8%, signal=27% GLUTATHIONE METABOLIC PROCESS%GOBP%GO:0006749 GLUTATHIONE METABOLIC PROCESS%GOBP%GO:0006749 35 -0.3425097 -0.99117017 0.4489796 0.5731912 1.0 4488 tags=57%, list=30%, signal=81% NUCLEOSIDE CATABOLIC PROCESS%GOBP%GO:0009164 NUCLEOSIDE CATABOLIC PROCESS%GOBP%GO:0009164 19 -0.40070087 -0.9906347 0.44702843 0.574005 1.0 1848 tags=26%, list=12%, signal=30% NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION%GOBP%GO:2001251 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION%GOBP%GO:2001251 82 -0.28737137 -0.99031484 0.45238096 0.5743591 1.0 3584 tags=28%, list=24%, signal=36% CELLULAR BIOGENIC AMINE METABOLIC PROCESS%GOBP%GO:0006576 CELLULAR BIOGENIC AMINE METABOLIC PROCESS%GOBP%GO:0006576 32 -0.35024777 -0.9897078 0.45614034 0.5753691 1.0 3256 tags=28%, list=21%, signal=36% LYSOSOME ORGANIZATION%GOBP%GO:0007040 LYSOSOME ORGANIZATION%GOBP%GO:0007040 36 -0.33977708 -0.9887857 0.4633431 0.5770583 1.0 2128 tags=17%, list=14%, signal=19% CELLULAR AMINE METABOLIC PROCESS%GOBP%GO:0044106 CELLULAR AMINE METABOLIC PROCESS%GOBP%GO:0044106 32 -0.35024777 -0.9883522 0.4520958 0.57768613 1.0 3256 tags=28%, list=21%, signal=36% PROTEIN REFOLDING%GOBP%GO:0042026 PROTEIN REFOLDING%GOBP%GO:0042026 17 -0.40298218 -0.9877439 0.47103274 0.5786955 1.0 2055 tags=24%, list=14%, signal=27% RESPONSE TO EXTRACELLULAR STIMULUS%GOBP%GO:0009991 RESPONSE TO EXTRACELLULAR STIMULUS%GOBP%GO:0009991 146 -0.26599553 -0.98695 0.559633 0.58015347 1.0 2834 tags=21%, list=19%, signal=26% CELLULAR IRON ION HOMEOSTASIS%GOBP%GO:0006879 CELLULAR IRON ION HOMEOSTASIS%GOBP%GO:0006879 44 -0.32078597 -0.9853755 0.45614034 0.58328134 1.0 2560 tags=25%, list=17%, signal=30% REGULATION OF COMPLEMENT ACTIVATION%GOBP%GO:0030449 REGULATION OF COMPLEMENT ACTIVATION%GOBP%GO:0030449 33 -0.34042928 -0.98409283 0.4570552 0.5858378 1.0 2016 tags=27%, list=13%, signal=31% E2F TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%E2F TRANSCRIPTION FACTOR NETWORK E2F TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%E2F TRANSCRIPTION FACTOR NETWORK 69 -0.29677498 -0.9839804 0.460177 0.58572876 1.0 1787 tags=28%, list=12%, signal=31% FATTY ACID SYNTHESIS%REACTOME%R-HSA-8978870.1 FATTY ACID SYNTHESIS%REACTOME%R-HSA-8978870.1 80 -0.28347048 -0.9839166 0.5 0.58550256 1.0 1470 tags=15%, list=10%, signal=17% CORTICAL ACTIN CYTOSKELETON ORGANIZATION%GOBP%GO:0030866 CORTICAL ACTIN CYTOSKELETON ORGANIZATION%GOBP%GO:0030866 15 -0.4131079 -0.98174906 0.49881798 0.5900995 1.0 1963 tags=27%, list=13%, signal=31% CELLULAR RESPONSE TO MECHANICAL STIMULUS%GOBP%GO:0071260 CELLULAR RESPONSE TO MECHANICAL STIMULUS%GOBP%GO:0071260 41 -0.3312317 -0.9813304 0.4681648 0.5907262 1.0 862 tags=17%, list=6%, signal=18% CXCR4-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CXCR4-MEDIATED SIGNALING EVENTS CXCR4-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CXCR4-MEDIATED SIGNALING EVENTS 81 -0.28528056 -0.9811107 0.5 0.59087986 1.0 1474 tags=16%, list=10%, signal=18% PROTEIN METHYLATION%GOBP%GO:0006479 PROTEIN METHYLATION%GOBP%GO:0006479 62 -0.2975071 -0.9800408 0.47247708 0.5929049 1.0 3481 tags=26%, list=23%, signal=33% NUCLEOBASE METABOLIC PROCESS%GOBP%GO:0009112 NUCLEOBASE METABOLIC PROCESS%GOBP%GO:0009112 18 -0.3868775 -0.97964394 0.47252747 0.5934292 1.0 4025 tags=44%, list=26%, signal=60% P53 PATHWAY%PANTHER PATHWAY%P00059 P53 PATHWAY%PANTHER PATHWAY%P00059 43 -0.32926428 -0.9787864 0.5337838 0.5950383 1.0 3007 tags=28%, list=20%, signal=35% NEGATIVE REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032689 NEGATIVE REGULATION OF INTERFERON-GAMMA PRODUCTION%GOBP%GO:0032689 18 -0.39881912 -0.9785154 0.46981627 0.59529555 1.0 2135 tags=39%, list=14%, signal=45% REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL%GOBP%GO:0051881 REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL%GOBP%GO:0051881 38 -0.33109418 -0.97847 0.4642857 0.5950234 1.0 2265 tags=34%, list=15%, signal=40% PID_E2F_PATHWAY%MSIGDB_C2%PID_E2F_PATHWAY PID_E2F_PATHWAY%MSIGDB_C2%PID_E2F_PATHWAY 69 -0.29677486 -0.97811544 0.5550239 0.5954491 1.0 1787 tags=28%, list=12%, signal=31% REGULATION OF PH%GOBP%GO:0006885 REGULATION OF PH%GOBP%GO:0006885 66 -0.2930139 -0.9780883 0.50212765 0.595153 1.0 4223 tags=29%, list=28%, signal=40% MEMBRANE DOCKING%GOBP%GO:0022406 MEMBRANE DOCKING%GOBP%GO:0022406 138 -0.26260793 -0.9777386 0.52903223 0.5955596 1.0 2910 tags=20%, list=19%, signal=25% FORMATION OF THE BETA-CATENIN:TCF TRANSACTIVATING COMPLEX%REACTOME DATABASE ID RELEASE 60%201722 FORMATION OF THE BETA-CATENIN:TCF TRANSACTIVATING COMPLEX%REACTOME DATABASE ID RELEASE 60%201722 60 -0.29315805 -0.9746939 0.48739496 0.6022306 1.0 4337 tags=40%, list=29%, signal=56% REGULATION OF PROTEIN ACTIVATION CASCADE%GOBP%GO:2000257 REGULATION OF PROTEIN ACTIVATION CASCADE%GOBP%GO:2000257 33 -0.34042928 -0.97285557 0.4966216 0.60605305 1.0 2016 tags=27%, list=13%, signal=31% POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS%GOBP%GO:0042993 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS%GOBP%GO:0042993 37 -0.3323584 -0.9722476 0.5063694 0.60701776 1.0 939 tags=11%, list=6%, signal=11% NEUROMUSCULAR PROCESS%GOBP%GO:0050905 NEUROMUSCULAR PROCESS%GOBP%GO:0050905 18 -0.40363875 -0.972107 0.49238577 0.60701966 1.0 547 tags=17%, list=4%, signal=17% SULFUR AMINO ACID METABOLISM%REACTOME DATABASE ID RELEASE 60%1614635 SULFUR AMINO ACID METABOLISM%REACTOME DATABASE ID RELEASE 60%1614635 21 -0.3790774 -0.97127104 0.4972826 0.60860926 1.0 4903 tags=67%, list=32%, signal=98% GLUCOSE TRANSPORT%REACTOME DATABASE ID RELEASE 60%70153 GLUCOSE TRANSPORT%REACTOME DATABASE ID RELEASE 60%70153 35 -0.3396106 -0.9701553 0.4888179 0.6107241 1.0 4293 tags=46%, list=28%, signal=64% EMBRYONIC PATTERN SPECIFICATION%GOBP%GO:0009880 EMBRYONIC PATTERN SPECIFICATION%GOBP%GO:0009880 21 -0.3704153 -0.9688643 0.4973404 0.61336255 1.0 1876 tags=33%, list=12%, signal=38% CELLULAR RESPONSE TO EXTERNAL STIMULUS%GOBP%GO:0071496 CELLULAR RESPONSE TO EXTERNAL STIMULUS%GOBP%GO:0071496 149 -0.25881237 -0.96832025 0.5241935 0.6141962 1.0 2244 tags=17%, list=15%, signal=20% NEGATIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904357 NEGATIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING%GOBP%GO:1904357 22 -0.37350145 -0.968288 0.48031497 0.61390436 1.0 1156 tags=18%, list=8%, signal=20% PROTEIN ALKYLATION%GOBP%GO:0008213 PROTEIN ALKYLATION%GOBP%GO:0008213 62 -0.2975071 -0.9678667 0.5019763 0.61445546 1.0 3481 tags=26%, list=23%, signal=33% REGULATION OF CHROMATIN SILENCING%GOBP%GO:0031935 REGULATION OF CHROMATIN SILENCING%GOBP%GO:0031935 19 -0.38852873 -0.9666859 0.530504 0.61682355 1.0 3370 tags=47%, list=22%, signal=61% RESPONSE TO STARVATION%GOBP%GO:0042594 RESPONSE TO STARVATION%GOBP%GO:0042594 94 -0.276021 -0.9658117 0.5029586 0.6184124 1.0 2834 tags=19%, list=19%, signal=23% METABOLISM OF FOLATE AND PTERINES%REACTOME DATABASE ID RELEASE 60%196757 METABOLISM OF FOLATE AND PTERINES%REACTOME DATABASE ID RELEASE 60%196757 16 -0.40616038 -0.9652178 0.50639385 0.6193551 1.0 2654 tags=25%, list=17%, signal=30% AXONAL TRANSPORT%GOBP%GO:0098930 AXONAL TRANSPORT%GOBP%GO:0098930 26 -0.35607326 -0.9651641 0.49137932 0.6190973 1.0 1235 tags=15%, list=8%, signal=17% GLUTATHIONE-MEDIATED DETOXIFICATION I%HUMANCYC%PWY-4061 GLUTATHIONE-MEDIATED DETOXIFICATION I%HUMANCYC%PWY-4061 20 -0.37592596 -0.9638111 0.49859944 0.6218565 1.0 2794 tags=45%, list=18%, signal=55% REGULATION OF MICROTUBULE-BASED PROCESS%GOBP%GO:0032886 REGULATION OF MICROTUBULE-BASED PROCESS%GOBP%GO:0032886 116 -0.26268113 -0.96255255 0.5874126 0.6243736 1.0 2534 tags=21%, list=17%, signal=25% RESPONSE TO NUTRIENT LEVELS%GOBP%GO:0031667 RESPONSE TO NUTRIENT LEVELS%GOBP%GO:0031667 136 -0.26382613 -0.96102285 0.53333336 0.6274995 1.0 2834 tags=20%, list=19%, signal=24% MITOTIC G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0031571 MITOTIC G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0031571 66 -0.28985938 -0.96001834 0.51965064 0.62942576 1.0 3399 tags=32%, list=22%, signal=41% REGULATION OF INTERLEUKIN-1 SECRETION%GOBP%GO:0050704 REGULATION OF INTERLEUKIN-1 SECRETION%GOBP%GO:0050704 23 -0.35942188 -0.9590038 0.50406504 0.631481 1.0 849 tags=13%, list=6%, signal=14% PHOTOTRANSDUCTION%GOBP%GO:0007602 PHOTOTRANSDUCTION%GOBP%GO:0007602 16 -0.39831778 -0.9583735 0.50842696 0.632537 1.0 731 tags=13%, list=5%, signal=13% G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0044783 G1 DNA DAMAGE CHECKPOINT%GOBP%GO:0044783 67 -0.28950065 -0.9574952 0.5414847 0.6341912 1.0 3399 tags=31%, list=22%, signal=40% REGULATION OF TORC1 SIGNALING%GOBP%GO:1903432 REGULATION OF TORC1 SIGNALING%GOBP%GO:1903432 24 -0.36293596 -0.9561835 0.5097493 0.6369025 1.0 2107 tags=21%, list=14%, signal=24% POSITIVE REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS%GOBP%GO:0043280 POSITIVE REGULATION OF CYSTEINE-TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS%GOBP%GO:0043280 89 -0.27768508 -0.9561629 0.53333336 0.63655657 1.0 2915 tags=27%, list=19%, signal=33% REGULATION OF TELOMERASE ACTIVITY%GOBP%GO:0051972 REGULATION OF TELOMERASE ACTIVITY%GOBP%GO:0051972 45 -0.31417418 -0.9558501 0.54285717 0.6368698 1.0 3544 tags=31%, list=23%, signal=40% REGULATION OF INTERLEUKIN-1 BETA SECRETION%GOBP%GO:0050706 REGULATION OF INTERLEUKIN-1 BETA SECRETION%GOBP%GO:0050706 20 -0.37209976 -0.9547891 0.52394366 0.63888127 1.0 849 tags=15%, list=6%, signal=16% PIGMENT GRANULE ORGANIZATION%GOBP%GO:0048753 PIGMENT GRANULE ORGANIZATION%GOBP%GO:0048753 18 -0.3901916 -0.9538481 0.50797874 0.6407373 1.0 2786 tags=28%, list=18%, signal=34% SIG_BCR_SIGNALING_PATHWAY%MSIGDB_C2%SIG_BCR_SIGNALING_PATHWAY SIG_BCR_SIGNALING_PATHWAY%MSIGDB_C2%SIG_BCR_SIGNALING_PATHWAY 45 -0.31231707 -0.9535978 0.5387454 0.64092284 1.0 3843 tags=36%, list=25%, signal=47% CELLULAR RESPONSE TO LIPOPOLYSACCHARIDE%GOBP%GO:0071222 CELLULAR RESPONSE TO LIPOPOLYSACCHARIDE%GOBP%GO:0071222 60 -0.29438028 -0.9521809 0.5540541 0.64378524 1.0 2864 tags=27%, list=19%, signal=33% HISTONE H3 ACETYLATION%GOBP%GO:0043966 HISTONE H3 ACETYLATION%GOBP%GO:0043966 37 -0.32384807 -0.9521724 0.5102041 0.64341503 1.0 3831 tags=32%, list=25%, signal=43% NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903363 NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS%GOBP%GO:1903363 35 -0.32354563 -0.94959223 0.5442623 0.6490586 1.0 3974 tags=34%, list=26%, signal=46% SENSORY PERCEPTION OF CHEMICAL STIMULUS%GOBP%GO:0007606 SENSORY PERCEPTION OF CHEMICAL STIMULUS%GOBP%GO:0007606 24 -0.35691944 -0.94723904 0.5833333 0.65434116 1.0 1561 tags=17%, list=10%, signal=19% NEUTROPHIL MIGRATION%GOBP%GO:1990266 NEUTROPHIL MIGRATION%GOBP%GO:1990266 42 -0.3050723 -0.94723815 0.5390335 0.6539482 1.0 3875 tags=36%, list=25%, signal=48% RESPONSE TO NUTRIENT%GOBP%GO:0007584 RESPONSE TO NUTRIENT%GOBP%GO:0007584 31 -0.33025283 -0.94664425 0.53745925 0.65492237 1.0 3083 tags=26%, list=20%, signal=32% CCR1%IOB%CCR1 CCR1%IOB%CCR1 25 -0.3487277 -0.9460023 0.5363129 0.6560552 1.0 887 tags=20%, list=6%, signal=21% NEGATIVE REGULATION OF OXIDATIVE STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902176 NEGATIVE REGULATION OF OXIDATIVE STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902176 16 -0.40837714 -0.94588745 0.5541237 0.65593374 1.0 4589 tags=44%, list=30%, signal=63% BRANCHED-CHAIN AMINO ACID METABOLIC PROCESS%GOBP%GO:0009081 BRANCHED-CHAIN AMINO ACID METABOLIC PROCESS%GOBP%GO:0009081 23 -0.3630126 -0.94484866 0.53125 0.6579022 1.0 3031 tags=43%, list=20%, signal=54% TOLL LIKE RECEPTOR 10 (TLR10) CASCADE%REACTOME DATABASE ID RELEASE 60%168142 TOLL LIKE RECEPTOR 10 (TLR10) CASCADE%REACTOME DATABASE ID RELEASE 60%168142 84 -0.2700431 -0.9444629 0.5735294 0.65836173 1.0 3183 tags=25%, list=21%, signal=31% BIOCARTA_GLEEVEC_PATHWAY%MSIGDB_C2%BIOCARTA_GLEEVEC_PATHWAY BIOCARTA_GLEEVEC_PATHWAY%MSIGDB_C2%BIOCARTA_GLEEVEC_PATHWAY 23 -0.35255787 -0.9441094 0.5412088 0.6587876 1.0 294 tags=9%, list=2%, signal=9% CELLULAR RESPONSE TO IONIZING RADIATION%GOBP%GO:0071479 CELLULAR RESPONSE TO IONIZING RADIATION%GOBP%GO:0071479 42 -0.31059405 -0.94325835 0.5610561 0.66035527 1.0 1385 tags=14%, list=9%, signal=16% PHOSPHOLIPID METABOLISM%REACTOME%R-HSA-1483257.1 PHOSPHOLIPID METABOLISM%REACTOME%R-HSA-1483257.1 189 -0.24526958 -0.94301564 0.6818182 0.66048914 1.0 1768 tags=14%, list=12%, signal=15% ACTIN FILAMENT POLYMERIZATION%GOBP%GO:0030041 ACTIN FILAMENT POLYMERIZATION%GOBP%GO:0030041 15 -0.4028676 -0.9415186 0.54987836 0.6635813 1.0 2257 tags=27%, list=15%, signal=31% HSP90 CHAPERONE CYCLE FOR SHRS%REACTOME%R-HSA-3371497.1 HSP90 CHAPERONE CYCLE FOR SHRS%REACTOME%R-HSA-3371497.1 30 -0.3321001 -0.93977875 0.57522124 0.66722506 1.0 1800 tags=17%, list=12%, signal=19% NEUTROPHIL CHEMOTAXIS%GOBP%GO:0030593 NEUTROPHIL CHEMOTAXIS%GOBP%GO:0030593 41 -0.30962938 -0.9385517 0.56785715 0.66977453 1.0 3875 tags=37%, list=25%, signal=49% GOLGI ASSOCIATED VESICLE BIOGENESIS%REACTOME%R-HSA-432722.3 GOLGI ASSOCIATED VESICLE BIOGENESIS%REACTOME%R-HSA-432722.3 52 -0.3009469 -0.9379881 0.56273764 0.6706556 1.0 2786 tags=21%, list=18%, signal=26% REGULATION OF GLYCOPROTEIN METABOLIC PROCESS%GOBP%GO:1903018 REGULATION OF GLYCOPROTEIN METABOLIC PROCESS%GOBP%GO:1903018 30 -0.3269871 -0.93779624 0.5650794 0.6707095 1.0 2828 tags=27%, list=19%, signal=33% T CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002286 T CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002286 25 -0.34787494 -0.9373655 0.5473373 0.67131954 1.0 2864 tags=32%, list=19%, signal=39% NEGATIVE REGULATION OF DNA RECOMBINATION%GOBP%GO:0045910 NEGATIVE REGULATION OF DNA RECOMBINATION%GOBP%GO:0045910 15 -0.3928494 -0.9371877 0.52505964 0.6713517 1.0 6122 tags=60%, list=40%, signal=100% PROTEIN COMPLEX LOCALIZATION%GOBP%GO:0031503 PROTEIN COMPLEX LOCALIZATION%GOBP%GO:0031503 61 -0.28458583 -0.9358958 0.58035713 0.6738907 1.0 1945 tags=18%, list=13%, signal=21% REGULATION OF ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0046637 REGULATION OF ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0046637 28 -0.34670553 -0.93551034 0.5692308 0.67440814 1.0 2140 tags=36%, list=14%, signal=41% DETECTION OF LIGHT STIMULUS%GOBP%GO:0009583 DETECTION OF LIGHT STIMULUS%GOBP%GO:0009583 20 -0.36368933 -0.9351847 0.53846157 0.6747685 1.0 1306 tags=15%, list=9%, signal=16% MITOTIC G1/S TRANSITION CHECKPOINT%GOBP%GO:0044819 MITOTIC G1/S TRANSITION CHECKPOINT%GOBP%GO:0044819 66 -0.28985938 -0.9343133 0.609375 0.6764263 1.0 3399 tags=32%, list=22%, signal=41% PREASSEMBLY OF GPI ANCHOR IN ER MEMBRANE%GOBP%GO:0016254 PREASSEMBLY OF GPI ANCHOR IN ER MEMBRANE%GOBP%GO:0016254 15 -0.38443932 -0.93414 0.55 0.6764051 1.0 4167 tags=33%, list=27%, signal=46% MONONUCLEAR CELL MIGRATION%GOBP%GO:0071674 MONONUCLEAR CELL MIGRATION%GOBP%GO:0071674 31 -0.3245539 -0.9340937 0.5552147 0.67611814 1.0 186 tags=13%, list=1%, signal=13% TOLL LIKE RECEPTOR 5 (TLR5) CASCADE%REACTOME DATABASE ID RELEASE 60%168176 TOLL LIKE RECEPTOR 5 (TLR5) CASCADE%REACTOME DATABASE ID RELEASE 60%168176 84 -0.2700431 -0.93265647 0.60487807 0.67895657 1.0 3183 tags=25%, list=21%, signal=31% CARGO RECOGNITION FOR CLATHRIN-MEDIATED ENDOCYTOSIS%REACTOME DATABASE ID RELEASE 60%8856825 CARGO RECOGNITION FOR CLATHRIN-MEDIATED ENDOCYTOSIS%REACTOME DATABASE ID RELEASE 60%8856825 91 -0.26212683 -0.93253595 0.66129035 0.6788264 1.0 1632 tags=13%, list=11%, signal=15% POSITIVE REGULATION OF MONOOXYGENASE ACTIVITY%GOBP%GO:0032770 POSITIVE REGULATION OF MONOOXYGENASE ACTIVITY%GOBP%GO:0032770 16 -0.38885766 -0.93165433 0.573201 0.680445 1.0 4092 tags=31%, list=27%, signal=43% CELL DIVISION%GOBP%GO:0051301 CELL DIVISION%GOBP%GO:0051301 122 -0.25400305 -0.92975414 0.66225165 0.6846361 1.0 2256 tags=20%, list=15%, signal=23% MYD88 CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%975871 MYD88 CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%975871 84 -0.2700431 -0.92914426 0.559633 0.68564457 1.0 3183 tags=25%, list=21%, signal=31% CASPASE CASCADE IN APOPTOSIS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CASPASE CASCADE IN APOPTOSIS CASPASE CASCADE IN APOPTOSIS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CASPASE CASCADE IN APOPTOSIS 47 -0.29831624 -0.92910874 0.5735294 0.685322 1.0 3345 tags=28%, list=22%, signal=35% REGULATION OF INTERLEUKIN-2 PRODUCTION%GOBP%GO:0032663 REGULATION OF INTERLEUKIN-2 PRODUCTION%GOBP%GO:0032663 31 -0.33196592 -0.92711735 0.58842444 0.68955433 1.0 2530 tags=32%, list=17%, signal=39% PID_CASPASE_PATHWAY%MSIGDB_C2%PID_CASPASE_PATHWAY PID_CASPASE_PATHWAY%MSIGDB_C2%PID_CASPASE_PATHWAY 49 -0.2933949 -0.9269679 0.55598456 0.6894893 1.0 3345 tags=27%, list=22%, signal=34% MONOCYTE CHEMOTAXIS%GOBP%GO:0002548 MONOCYTE CHEMOTAXIS%GOBP%GO:0002548 30 -0.32509246 -0.9267607 0.55910546 0.68953943 1.0 186 tags=13%, list=1%, signal=13% REGULATION OF CENTROSOME DUPLICATION%GOBP%GO:0010824 REGULATION OF CENTROSOME DUPLICATION%GOBP%GO:0010824 29 -0.33535114 -0.9259102 0.57096773 0.6910982 1.0 4946 tags=48%, list=33%, signal=71% PROTEIN IMPORT%GOBP%GO:0017038 PROTEIN IMPORT%GOBP%GO:0017038 124 -0.25520507 -0.9257124 0.6879433 0.6911265 1.0 3106 tags=26%, list=20%, signal=32% PROTEIN LOCALIZATION TO MICROTUBULE CYTOSKELETON%GOBP%GO:0072698 PROTEIN LOCALIZATION TO MICROTUBULE CYTOSKELETON%GOBP%GO:0072698 22 -0.34834495 -0.92502725 0.5679348 0.69235224 1.0 1855 tags=18%, list=12%, signal=21% POSITIVE REGULATION OF BLOOD VESSEL DIAMETER%GOBP%GO:0097755 POSITIVE REGULATION OF BLOOD VESSEL DIAMETER%GOBP%GO:0097755 15 -0.3953425 -0.9248545 0.5613208 0.692323 1.0 1209 tags=20%, list=8%, signal=22% PROTEIN-DNA COMPLEX DISASSEMBLY%GOBP%GO:0032986 PROTEIN-DNA COMPLEX DISASSEMBLY%GOBP%GO:0032986 18 -0.38488472 -0.924389 0.58090186 0.69297224 1.0 4182 tags=28%, list=27%, signal=38% PROTEIN K63-LINKED DEUBIQUITINATION%GOBP%GO:0070536 PROTEIN K63-LINKED DEUBIQUITINATION%GOBP%GO:0070536 23 -0.34539264 -0.9240454 0.556701 0.6933809 1.0 3718 tags=30%, list=24%, signal=40% CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043367 CD4-POSITIVE, ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0043367 17 -0.3783868 -0.9214726 0.5677083 0.6989237 1.0 2461 tags=41%, list=16%, signal=49% LONG-CHAIN FATTY ACID METABOLIC PROCESS%GOBP%GO:0001676 LONG-CHAIN FATTY ACID METABOLIC PROCESS%GOBP%GO:0001676 58 -0.28135148 -0.92124844 0.6150628 0.69903195 1.0 1470 tags=16%, list=10%, signal=17% ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0046632 ALPHA-BETA T CELL DIFFERENTIATION%GOBP%GO:0046632 20 -0.3642276 -0.9210524 0.5638298 0.69908 1.0 2606 tags=40%, list=17%, signal=48% GLYCEROLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0045017 GLYCEROLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0045017 184 -0.23450144 -0.9210136 0.75961536 0.6987508 1.0 1684 tags=13%, list=11%, signal=14% REGULATION OF MICROTUBULE CYTOSKELETON ORGANIZATION%GOBP%GO:0070507 REGULATION OF MICROTUBULE CYTOSKELETON ORGANIZATION%GOBP%GO:0070507 98 -0.26218644 -0.917429 0.72 0.7067366 1.0 2430 tags=21%, list=16%, signal=25% GMCSF-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%GMCSF-MEDIATED SIGNALING EVENTS GMCSF-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%GMCSF-MEDIATED SIGNALING EVENTS 34 -0.3197924 -0.9160942 0.625387 0.7093851 1.0 3770 tags=35%, list=25%, signal=47% SIGNALING BY FGFR2 IIIA TM%REACTOME%R-HSA-8851708.1 SIGNALING BY FGFR2 IIIA TM%REACTOME%R-HSA-8851708.1 19 -0.36227328 -0.9132147 0.5862069 0.71564853 1.0 2682 tags=42%, list=18%, signal=51% VIRAL ENTRY INTO HOST CELL%GOBP%GO:0046718 VIRAL ENTRY INTO HOST CELL%GOBP%GO:0046718 24 -0.34419155 -0.9122373 0.61904764 0.71750087 1.0 2643 tags=29%, list=17%, signal=35% CELLULAR RESPONSE TO RADIATION%GOBP%GO:0071478 CELLULAR RESPONSE TO RADIATION%GOBP%GO:0071478 103 -0.2484258 -0.910939 0.724359 0.7201847 1.0 1385 tags=14%, list=9%, signal=15% CYTOSKELETON-DEPENDENT CYTOKINESIS%GOBP%GO:0061640 CYTOSKELETON-DEPENDENT CYTOKINESIS%GOBP%GO:0061640 38 -0.30780616 -0.91007924 0.64285713 0.72175086 1.0 2428 tags=32%, list=16%, signal=37% M-CSF%IOB%M-CSF M-CSF%IOB%M-CSF 61 -0.2818813 -0.9091897 0.632 0.72339106 1.0 2451 tags=21%, list=16%, signal=25% GLYCEROPHOSPHOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0046474 GLYCEROPHOSPHOLIPID BIOSYNTHETIC PROCESS%GOBP%GO:0046474 176 -0.23853917 -0.9091321 0.7826087 0.72310317 1.0 1684 tags=13%, list=11%, signal=15% PID_P53_REGULATION_PATHWAY%MSIGDB_C2%PID_P53_REGULATION_PATHWAY PID_P53_REGULATION_PATHWAY%MSIGDB_C2%PID_P53_REGULATION_PATHWAY 58 -0.27596885 -0.90860385 0.65863454 0.7238913 1.0 1069 tags=10%, list=7%, signal=11% AUTOPHAGOSOME ASSEMBLY%GOBP%GO:0000045 AUTOPHAGOSOME ASSEMBLY%GOBP%GO:0000045 30 -0.3252643 -0.90849066 0.61564624 0.7237034 1.0 678 tags=7%, list=4%, signal=7% PEPTIDYL-TYROSINE AUTOPHOSPHORYLATION%GOBP%GO:0038083 PEPTIDYL-TYROSINE AUTOPHOSPHORYLATION%GOBP%GO:0038083 41 -0.30140948 -0.9078746 0.5993031 0.72466564 1.0 2985 tags=34%, list=20%, signal=42% TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION%REACTOME DATABASE ID RELEASE 60%975138 TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION%REACTOME DATABASE ID RELEASE 60%975138 91 -0.26112112 -0.90780425 0.7292818 0.72440076 1.0 2571 tags=20%, list=17%, signal=24% PYRUVATE METABOLIC PROCESS%GOBP%GO:0006090 PYRUVATE METABOLIC PROCESS%GOBP%GO:0006090 47 -0.2910436 -0.90621054 0.6262976 0.7275699 1.0 4865 tags=40%, list=32%, signal=59% CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS%GOBP%GO:0031668 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS%GOBP%GO:0031668 111 -0.25265712 -0.90592986 0.7443609 0.72780615 1.0 2834 tags=20%, list=19%, signal=24% CELLULAR LIPID CATABOLIC PROCESS%GOBP%GO:0044242 CELLULAR LIPID CATABOLIC PROCESS%GOBP%GO:0044242 116 -0.24759379 -0.904116 0.76865673 0.7315728 1.0 3250 tags=29%, list=21%, signal=37% MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY%GOBP%GO:0019048 MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY%GOBP%GO:0019048 29 -0.3285139 -0.9040768 0.6090909 0.7312444 1.0 2652 tags=21%, list=17%, signal=25% EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS%GOBP%GO:0008625 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS%GOBP%GO:0008625 26 -0.33776256 -0.903487 0.5701754 0.7321525 1.0 4791 tags=46%, list=31%, signal=67% CELLULAR RESPONSE TO NUTRIENT LEVELS%GOBP%GO:0031669 CELLULAR RESPONSE TO NUTRIENT LEVELS%GOBP%GO:0031669 104 -0.2531088 -0.9016544 0.69005847 0.73597944 1.0 3762 tags=25%, list=25%, signal=33% AUTOPHAGOSOME ORGANIZATION%GOBP%GO:1905037 AUTOPHAGOSOME ORGANIZATION%GOBP%GO:1905037 31 -0.31656206 -0.90154415 0.60596025 0.7358242 1.0 678 tags=6%, list=4%, signal=7% MTOR SIGNALLING%REACTOME%R-HSA-165159.4 MTOR SIGNALLING%REACTOME%R-HSA-165159.4 34 -0.31688875 -0.9012347 0.6363636 0.7361347 1.0 3651 tags=24%, list=24%, signal=31% RESPONSE TO UV%GOBP%GO:0009411 RESPONSE TO UV%GOBP%GO:0009411 101 -0.24985966 -0.9007399 0.80813956 0.7368644 1.0 1469 tags=14%, list=10%, signal=15% BIOCARTA_CDMAC_PATHWAY%MSIGDB_C2%BIOCARTA_CDMAC_PATHWAY BIOCARTA_CDMAC_PATHWAY%MSIGDB_C2%BIOCARTA_CDMAC_PATHWAY 16 -0.3760485 -0.89924556 0.59322035 0.73976046 1.0 421 tags=13%, list=3%, signal=13% TRANSCRIPTION REGULATION BY BZIP TRANSCRIPTION FACTOR%PANTHER PATHWAY%P00055 TRANSCRIPTION REGULATION BY BZIP TRANSCRIPTION FACTOR%PANTHER PATHWAY%P00055 42 -0.3009487 -0.8976848 0.63468635 0.7428031 1.0 3127 tags=36%, list=21%, signal=45% PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 37 -0.30776945 -0.89755195 0.6229508 0.7426883 1.0 2593 tags=22%, list=17%, signal=26% HISTONE DEACETYLATION%GOBP%GO:0016575 HISTONE DEACETYLATION%GOBP%GO:0016575 31 -0.31688762 -0.8962383 0.625 0.74525607 1.0 3136 tags=19%, list=21%, signal=24% P53 PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%P53 PATHWAY P53 PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%P53 PATHWAY 58 -0.2759689 -0.89407253 0.6832061 0.74964637 1.0 1069 tags=10%, list=7%, signal=11% HOMEOSTASIS OF NUMBER OF CELLS%GOBP%GO:0048872 HOMEOSTASIS OF NUMBER OF CELLS%GOBP%GO:0048872 53 -0.28696653 -0.8931669 0.7027027 0.75120056 1.0 1204 tags=15%, list=8%, signal=16% GPVI-MEDIATED ACTIVATION CASCADE%REACTOME DATABASE ID RELEASE 60%114604 GPVI-MEDIATED ACTIVATION CASCADE%REACTOME DATABASE ID RELEASE 60%114604 47 -0.29075575 -0.89168215 0.6549296 0.7540411 1.0 1204 tags=19%, list=8%, signal=21% POSITIVE REGULATION OF CHROMATIN ORGANIZATION%GOBP%GO:1905269 POSITIVE REGULATION OF CHROMATIN ORGANIZATION%GOBP%GO:1905269 63 -0.26957074 -0.8880396 0.6784141 0.7616981 1.0 4719 tags=38%, list=31%, signal=55% PID_GMCSF_PATHWAY%MSIGDB_C2%PID_GMCSF_PATHWAY PID_GMCSF_PATHWAY%MSIGDB_C2%PID_GMCSF_PATHWAY 35 -0.3100418 -0.8879649 0.66049385 0.7614201 1.0 3770 tags=34%, list=25%, signal=45% PROTEIN K48-LINKED UBIQUITINATION%GOBP%GO:0070936 PROTEIN K48-LINKED UBIQUITINATION%GOBP%GO:0070936 46 -0.28579435 -0.886784 0.6923077 0.7635847 1.0 3882 tags=30%, list=26%, signal=41% MICROTUBULE-BASED MOVEMENT%GOBP%GO:0007018 MICROTUBULE-BASED MOVEMENT%GOBP%GO:0007018 168 -0.2290755 -0.88674146 0.8938053 0.7632452 1.0 2898 tags=21%, list=19%, signal=26% SULFUR COMPOUND TRANSPORT%GOBP%GO:0072348 SULFUR COMPOUND TRANSPORT%GOBP%GO:0072348 22 -0.34422415 -0.88585967 0.6475196 0.76473886 1.0 1771 tags=14%, list=12%, signal=15% ACUTE INFLAMMATORY RESPONSE%GOBP%GO:0002526 ACUTE INFLAMMATORY RESPONSE%GOBP%GO:0002526 16 -0.36989152 -0.8856367 0.64631045 0.76481426 1.0 162 tags=13%, list=1%, signal=13% NEGATIVE REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032720 NEGATIVE REGULATION OF TUMOR NECROSIS FACTOR PRODUCTION%GOBP%GO:0032720 21 -0.3491855 -0.8843692 0.6230366 0.76725096 1.0 3154 tags=38%, list=21%, signal=48% MRNA TRANSCRIPTION%GOBP%GO:0009299 MRNA TRANSCRIPTION%GOBP%GO:0009299 17 -0.35568616 -0.88421583 0.6311881 0.76715374 1.0 903 tags=12%, list=6%, signal=12% UNSATURATED FATTY ACID METABOLIC PROCESS%GOBP%GO:0033559 UNSATURATED FATTY ACID METABOLIC PROCESS%GOBP%GO:0033559 65 -0.26680735 -0.8827565 0.7457627 0.769947 1.0 1470 tags=14%, list=10%, signal=15% MEMBRANE PROTEIN PROTEOLYSIS%GOBP%GO:0033619 MEMBRANE PROTEIN PROTEOLYSIS%GOBP%GO:0033619 31 -0.3118688 -0.88234717 0.67391306 0.77042514 1.0 3398 tags=35%, list=22%, signal=46% N-GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-532668.2 N-GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-532668.2 35 -0.29760018 -0.8818033 0.7007299 0.7711655 1.0 3204 tags=23%, list=21%, signal=29% RESPONSE TO ALKALOID%GOBP%GO:0043279 RESPONSE TO ALKALOID%GOBP%GO:0043279 28 -0.32460144 -0.88169354 0.6458333 0.7709626 1.0 4339 tags=36%, list=29%, signal=50% DOWNREGULATION OF ERBB2 SIGNALING%REACTOME DATABASE ID RELEASE 60%8863795 DOWNREGULATION OF ERBB2 SIGNALING%REACTOME DATABASE ID RELEASE 60%8863795 26 -0.32736316 -0.88154703 0.6582633 0.7708322 1.0 2755 tags=19%, list=18%, signal=23% BBSOME-MEDIATED CARGO-TARGETING TO CILIUM%REACTOME DATABASE ID RELEASE 60%5620922 BBSOME-MEDIATED CARGO-TARGETING TO CILIUM%REACTOME DATABASE ID RELEASE 60%5620922 20 -0.34612685 -0.8800373 0.6545454 0.7736357 1.0 5151 tags=50%, list=34%, signal=76% POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY%GOBP%GO:0031334 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY%GOBP%GO:0031334 156 -0.23512012 -0.8800352 0.88793105 0.773198 1.0 3181 tags=24%, list=21%, signal=30% LIPID MODIFICATION%GOBP%GO:0030258 LIPID MODIFICATION%GOBP%GO:0030258 98 -0.256967 -0.8788986 0.76506025 0.77525663 1.0 3063 tags=27%, list=20%, signal=33% TOLL LIKE RECEPTOR TLR6:TLR2 CASCADE%REACTOME DATABASE ID RELEASE 60%168188 TOLL LIKE RECEPTOR TLR6:TLR2 CASCADE%REACTOME DATABASE ID RELEASE 60%168188 94 -0.24693744 -0.87824017 0.83798885 0.7762305 1.0 2615 tags=21%, list=17%, signal=26% DEFECTS IN VITAMIN AND COFACTOR METABOLISM%REACTOME%R-HSA-3296482.1 DEFECTS IN VITAMIN AND COFACTOR METABOLISM%REACTOME%R-HSA-3296482.1 16 -0.36765406 -0.87719226 0.62842894 0.7781186 1.0 3087 tags=38%, list=20%, signal=47% DEADENYLATION OF MRNA%REACTOME%R-HSA-429947.2 DEADENYLATION OF MRNA%REACTOME%R-HSA-429947.2 24 -0.3298724 -0.8765706 0.65957445 0.77903736 1.0 5960 tags=46%, list=39%, signal=75% REGULATION OF CHROMATIN ORGANIZATION%GOBP%GO:1902275 REGULATION OF CHROMATIN ORGANIZATION%GOBP%GO:1902275 108 -0.24266994 -0.87586296 0.825 0.78015554 1.0 3103 tags=22%, list=20%, signal=28% VERY LONG-CHAIN FATTY ACID METABOLIC PROCESS%GOBP%GO:0000038 VERY LONG-CHAIN FATTY ACID METABOLIC PROCESS%GOBP%GO:0000038 18 -0.36474517 -0.87517226 0.6492537 0.7812385 1.0 4295 tags=33%, list=28%, signal=46% INTERMEDIATE FILAMENT-BASED PROCESS%GOBP%GO:0045103 INTERMEDIATE FILAMENT-BASED PROCESS%GOBP%GO:0045103 18 -0.34752816 -0.8749837 0.6641414 0.78119177 1.0 657 tags=11%, list=4%, signal=12% TOLL LIKE RECEPTOR TLR1:TLR2 CASCADE%REACTOME DATABASE ID RELEASE 60%168179 TOLL LIKE RECEPTOR TLR1:TLR2 CASCADE%REACTOME DATABASE ID RELEASE 60%168179 94 -0.24693744 -0.87481326 0.7748691 0.78109986 1.0 2615 tags=21%, list=17%, signal=26% POSITIVE REGULATION OF TRANSLATION%GOBP%GO:0045727 POSITIVE REGULATION OF TRANSLATION%GOBP%GO:0045727 67 -0.25740337 -0.8708061 0.80088496 0.789477 1.0 2277 tags=22%, list=15%, signal=26% RAF-INDEPENDENT MAPK1 3 ACTIVATION%REACTOME%R-HSA-112409.2 RAF-INDEPENDENT MAPK1 3 ACTIVATION%REACTOME%R-HSA-112409.2 22 -0.33649686 -0.8702231 0.6340058 0.7902788 1.0 934 tags=14%, list=6%, signal=15% TSLP%NETPATH%TSLP TSLP%NETPATH%TSLP 155 -0.23290005 -0.86842567 0.88135594 0.79359686 1.0 3043 tags=23%, list=20%, signal=28% DETECTION OF STIMULUS INVOLVED IN SENSORY PERCEPTION%GOBP%GO:0050906 DETECTION OF STIMULUS INVOLVED IN SENSORY PERCEPTION%GOBP%GO:0050906 22 -0.33206877 -0.8683095 0.6693989 0.79338884 1.0 1561 tags=23%, list=10%, signal=25% FLK2 FLT3%IOB%FLK2 FLT3 FLK2 FLT3%IOB%FLK2 FLT3 22 -0.3335501 -0.8675762 0.672043 0.79454243 1.0 3544 tags=36%, list=23%, signal=47% ZYMOGEN ACTIVATION%GOBP%GO:0031638 ZYMOGEN ACTIVATION%GOBP%GO:0031638 20 -0.3422103 -0.86693835 0.6887052 0.7954812 1.0 495 tags=15%, list=3%, signal=15% TOLL LIKE RECEPTOR 2 (TLR2) CASCADE%REACTOME%R-HSA-181438.1 TOLL LIKE RECEPTOR 2 (TLR2) CASCADE%REACTOME%R-HSA-181438.1 94 -0.24693744 -0.86642236 0.7777778 0.7961433 1.0 2615 tags=21%, list=17%, signal=26% MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS%GOBP%GO:0006509 MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS%GOBP%GO:0006509 18 -0.3565051 -0.865386 0.65356266 0.79783976 1.0 3242 tags=33%, list=21%, signal=42% CORTICAL CYTOSKELETON ORGANIZATION%GOBP%GO:0030865 CORTICAL CYTOSKELETON ORGANIZATION%GOBP%GO:0030865 20 -0.34199446 -0.86454284 0.66573036 0.7991499 1.0 1963 tags=20%, list=13%, signal=23% POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION%GOBP%GO:0002763 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION%GOBP%GO:0002763 22 -0.32792118 -0.8627744 0.67536235 0.8024596 1.0 3224 tags=36%, list=21%, signal=46% MYD88:MAL CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%166058 MYD88:MAL CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%166058 94 -0.24693744 -0.86064345 0.79444444 0.80658275 1.0 2615 tags=21%, list=17%, signal=26% STEROID HORMONES%REACTOME DATABASE ID RELEASE 60%209943 STEROID HORMONES%REACTOME DATABASE ID RELEASE 60%209943 28 -0.31192324 -0.8603972 0.6733524 0.80664104 1.0 4722 tags=32%, list=31%, signal=47% MODIFICATION BY SYMBIONT OF HOST MORPHOLOGY OR PHYSIOLOGY%GOBP%GO:0044003 MODIFICATION BY SYMBIONT OF HOST MORPHOLOGY OR PHYSIOLOGY%GOBP%GO:0044003 33 -0.3015981 -0.8602363 0.6971609 0.80653405 1.0 2652 tags=18%, list=17%, signal=22% REGULATION OF VIRAL RELEASE FROM HOST CELL%GOBP%GO:1902186 REGULATION OF VIRAL RELEASE FROM HOST CELL%GOBP%GO:1902186 27 -0.31475234 -0.8599789 0.6931507 0.80661714 1.0 276 tags=7%, list=2%, signal=8% NICOTINATE METABOLISM%REACTOME%R-HSA-196807.3 NICOTINATE METABOLISM%REACTOME%R-HSA-196807.3 25 -0.3270025 -0.85881466 0.7008547 0.80860794 1.0 1637 tags=24%, list=11%, signal=27% INTERMEDIATE FILAMENT CYTOSKELETON ORGANIZATION%GOBP%GO:0045104 INTERMEDIATE FILAMENT CYTOSKELETON ORGANIZATION%GOBP%GO:0045104 18 -0.34752816 -0.85735476 0.6744792 0.8112243 1.0 657 tags=11%, list=4%, signal=12% PROTEIN LOCALIZATION TO CYTOSKELETON%GOBP%GO:0044380 PROTEIN LOCALIZATION TO CYTOSKELETON%GOBP%GO:0044380 24 -0.3207479 -0.8563148 0.659375 0.81289744 1.0 1855 tags=17%, list=12%, signal=19% HALLMARK_PROTEIN_SECRETION%MSIGDB_C2%HALLMARK_PROTEIN_SECRETION HALLMARK_PROTEIN_SECRETION%MSIGDB_C2%HALLMARK_PROTEIN_SECRETION 95 -0.24679323 -0.8557676 0.7921348 0.81352645 1.0 3855 tags=26%, list=25%, signal=35% NEGATIVE REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034122 NEGATIVE REGULATION OF TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0034122 21 -0.33682835 -0.8557671 0.6923077 0.81306803 1.0 2327 tags=24%, list=15%, signal=28% PROTEIN HETEROTETRAMERIZATION%GOBP%GO:0051290 PROTEIN HETEROTETRAMERIZATION%GOBP%GO:0051290 22 -0.33662397 -0.8536187 0.7039106 0.8171679 1.0 1655 tags=23%, list=11%, signal=25% BIOCARTA_HCMV_PATHWAY%MSIGDB_C2%BIOCARTA_HCMV_PATHWAY BIOCARTA_HCMV_PATHWAY%MSIGDB_C2%BIOCARTA_HCMV_PATHWAY 17 -0.35588524 -0.85357565 0.64411026 0.816797 1.0 4966 tags=35%, list=33%, signal=52% REGULATION OF NEUROLOGICAL SYSTEM PROCESS%GOBP%GO:0031644 REGULATION OF NEUROLOGICAL SYSTEM PROCESS%GOBP%GO:0031644 18 -0.3430473 -0.85057515 0.6807388 0.8224907 1.0 2235 tags=28%, list=15%, signal=33% PID_TAP63_PATHWAY%MSIGDB_C2%PID_TAP63_PATHWAY PID_TAP63_PATHWAY%MSIGDB_C2%PID_TAP63_PATHWAY 50 -0.2693682 -0.85041964 0.78985506 0.8223593 1.0 1475 tags=16%, list=10%, signal=18% TRAF6 MEDIATED INDUCTION OF PROINFLAMMATORY CYTOKINES%REACTOME DATABASE ID RELEASE 60%168180 TRAF6 MEDIATED INDUCTION OF PROINFLAMMATORY CYTOKINES%REACTOME DATABASE ID RELEASE 60%168180 82 -0.24561302 -0.8484851 0.8333333 0.8258561 1.0 3183 tags=23%, list=21%, signal=29% CERAMIDE SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CERAMIDE SIGNALING PATHWAY CERAMIDE SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%CERAMIDE SIGNALING PATHWAY 43 -0.28498614 -0.84824735 0.69964665 0.82589126 1.0 1310 tags=16%, list=9%, signal=18% ARACHIDONIC ACID METABOLISM%REACTOME%R-HSA-2142753.4 ARACHIDONIC ACID METABOLISM%REACTOME%R-HSA-2142753.4 47 -0.273516 -0.8474864 0.75958186 0.82703274 1.0 1470 tags=15%, list=10%, signal=16% REGULATION OF MEMBRANE LIPID DISTRIBUTION%GOBP%GO:0097035 REGULATION OF MEMBRANE LIPID DISTRIBUTION%GOBP%GO:0097035 24 -0.3161765 -0.84694016 0.7227139 0.82766956 1.0 3891 tags=29%, list=26%, signal=39% REGULATION OF SIGNALING BY CBL%REACTOME%R-HSA-912631.1 REGULATION OF SIGNALING BY CBL%REACTOME%R-HSA-912631.1 17 -0.3567746 -0.8463405 0.7192118 0.8284155 1.0 3240 tags=35%, list=21%, signal=45% HETEROTRIMERIC G-PROTEIN SIGNALING PATHWAY-ROD OUTER SEGMENT PHOTOTRANSDUCTION%PANTHER PATHWAY%P00028 HETEROTRIMERIC G-PROTEIN SIGNALING PATHWAY-ROD OUTER SEGMENT PHOTOTRANSDUCTION%PANTHER PATHWAY%P00028 22 -0.32874975 -0.8452766 0.703504 0.83009654 1.0 808 tags=14%, list=5%, signal=14% PROTEIN LOCALIZATION TO MICROTUBULE ORGANIZING CENTER%GOBP%GO:1905508 PROTEIN LOCALIZATION TO MICROTUBULE ORGANIZING CENTER%GOBP%GO:1905508 15 -0.35801172 -0.8446739 0.67091835 0.83081377 1.0 1855 tags=13%, list=12%, signal=15% TRANSPORT ALONG MICROTUBULE%GOBP%GO:0010970 TRANSPORT ALONG MICROTUBULE%GOBP%GO:0010970 88 -0.23945443 -0.84258896 0.8556701 0.8345216 1.0 1975 tags=14%, list=13%, signal=16% METABOTROPIC GLUTAMATE RECEPTOR GROUP III PATHWAY%PANTHER PATHWAY%P00039 METABOTROPIC GLUTAMATE RECEPTOR GROUP III PATHWAY%PANTHER PATHWAY%P00039 49 -0.26784962 -0.841934 0.78039217 0.8353517 1.0 2162 tags=14%, list=14%, signal=17% REGULATION OF SUPEROXIDE METABOLIC PROCESS%GOBP%GO:0090322 REGULATION OF SUPEROXIDE METABOLIC PROCESS%GOBP%GO:0090322 15 -0.35933706 -0.84184355 0.6848635 0.8350441 1.0 2451 tags=33%, list=16%, signal=40% ASPARTATE FAMILY AMINO ACID BIOSYNTHETIC PROCESS%GOBP%GO:0009067 ASPARTATE FAMILY AMINO ACID BIOSYNTHETIC PROCESS%GOBP%GO:0009067 18 -0.33922708 -0.8417626 0.6955503 0.83470774 1.0 3829 tags=50%, list=25%, signal=67% GLUTATHIONE CONJUGATION%REACTOME%R-HSA-156590.2 GLUTATHIONE CONJUGATION%REACTOME%R-HSA-156590.2 32 -0.2963363 -0.8413721 0.78742516 0.8349971 1.0 4321 tags=50%, list=28%, signal=70% TRANSLOCATION OF GLUT4 TO THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%1445148 TRANSLOCATION OF GLUT4 TO THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 60%1445148 53 -0.25988516 -0.8407971 0.8312757 0.83567244 1.0 3846 tags=21%, list=25%, signal=28% REGULATION OF TP53 ACTIVITY THROUGH METHYLATION%REACTOME%R-HSA-6804760.1 REGULATION OF TP53 ACTIVITY THROUGH METHYLATION%REACTOME%R-HSA-6804760.1 17 -0.34356526 -0.84067583 0.6919431 0.8354523 1.0 2247 tags=18%, list=15%, signal=21% MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 60%1592230 MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 60%1592230 59 -0.26239613 -0.840626 0.796875 0.8350834 1.0 4034 tags=32%, list=27%, signal=44% IL1%NETPATH%IL1 IL1%NETPATH%IL1 67 -0.2574575 -0.8397115 0.817757 0.8363736 1.0 2487 tags=16%, list=16%, signal=20% ORGANOPHOSPHATE ESTER TRANSPORT%GOBP%GO:0015748 ORGANOPHOSPHATE ESTER TRANSPORT%GOBP%GO:0015748 46 -0.2743762 -0.83913696 0.8041958 0.83701444 1.0 3439 tags=26%, list=23%, signal=34% B CELL ACTIVATION%GOBP%GO:0042113 B CELL ACTIVATION%GOBP%GO:0042113 63 -0.2578859 -0.83872074 0.8072289 0.83736444 1.0 2363 tags=21%, list=16%, signal=24% ST_GAQ_PATHWAY%MSIGDB_C2%ST_GAQ_PATHWAY ST_GAQ_PATHWAY%MSIGDB_C2%ST_GAQ_PATHWAY 27 -0.313542 -0.8379122 0.74539876 0.8384429 1.0 3154 tags=26%, list=21%, signal=33% REGULATION OF RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:1905897 REGULATION OF RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:1905897 58 -0.2580623 -0.8354125 0.8062016 0.842799 1.0 2208 tags=19%, list=15%, signal=22% NEGATIVE REGULATION OF B CELL ACTIVATION%GOBP%GO:0050869 NEGATIVE REGULATION OF B CELL ACTIVATION%GOBP%GO:0050869 16 -0.3416821 -0.8353855 0.7044335 0.8423896 1.0 1826 tags=38%, list=12%, signal=43% PKMTS METHYLATE HISTONE LYSINES%REACTOME DATABASE ID RELEASE 60%3214841 PKMTS METHYLATE HISTONE LYSINES%REACTOME DATABASE ID RELEASE 60%3214841 50 -0.2673179 -0.8347024 0.8530466 0.8431648 1.0 3832 tags=32%, list=25%, signal=43% POSITIVE REGULATION OF HISTONE METHYLATION%GOBP%GO:0031062 POSITIVE REGULATION OF HISTONE METHYLATION%GOBP%GO:0031062 22 -0.32373905 -0.8336364 0.73333335 0.8447524 1.0 3103 tags=23%, list=20%, signal=29% PROTEIN LOCALIZATION TO CENTROSOME%GOBP%GO:0071539 PROTEIN LOCALIZATION TO CENTROSOME%GOBP%GO:0071539 15 -0.35801172 -0.8332779 0.65609753 0.84494764 1.0 1855 tags=13%, list=12%, signal=15% ANTIGEN ACTIVATES B CELL RECEPTOR (BCR) LEADING TO GENERATION OF SECOND MESSENGERS%REACTOME%R-HSA-983695.1 ANTIGEN ACTIVATES B CELL RECEPTOR (BCR) LEADING TO GENERATION OF SECOND MESSENGERS%REACTOME%R-HSA-983695.1 35 -0.29092488 -0.83241147 0.77591974 0.84612215 1.0 3498 tags=40%, list=23%, signal=52% CD28 CO-STIMULATION%REACTOME%R-HSA-389356.1 CD28 CO-STIMULATION%REACTOME%R-HSA-389356.1 30 -0.29737052 -0.8300782 0.74922603 0.84995663 1.0 3240 tags=33%, list=21%, signal=42% RESPONSE TO COLD%GOBP%GO:0009409 RESPONSE TO COLD%GOBP%GO:0009409 15 -0.3629553 -0.82980794 0.6956522 0.8500134 1.0 2055 tags=20%, list=14%, signal=23% ST_INTERLEUKIN_4_PATHWAY%MSIGDB_C2%ST_INTERLEUKIN_4_PATHWAY ST_INTERLEUKIN_4_PATHWAY%MSIGDB_C2%ST_INTERLEUKIN_4_PATHWAY 23 -0.31924018 -0.8285298 0.7277628 0.85193336 1.0 356 tags=9%, list=2%, signal=9% HALLMARK_PANCREAS_BETA_CELLS%MSIGDB_C2%HALLMARK_PANCREAS_BETA_CELLS HALLMARK_PANCREAS_BETA_CELLS%MSIGDB_C2%HALLMARK_PANCREAS_BETA_CELLS 23 -0.31692335 -0.82769233 0.7277937 0.85305744 1.0 1127 tags=13%, list=7%, signal=14% MICROTUBULE-BASED TRANSPORT%GOBP%GO:0099111 MICROTUBULE-BASED TRANSPORT%GOBP%GO:0099111 88 -0.23945443 -0.8259288 0.90909094 0.8559226 1.0 1975 tags=14%, list=13%, signal=16% BIOCARTA_IL6_PATHWAY%MSIGDB_C2%BIOCARTA_IL6_PATHWAY BIOCARTA_IL6_PATHWAY%MSIGDB_C2%BIOCARTA_IL6_PATHWAY 22 -0.31778473 -0.8253703 0.73976606 0.85650325 1.0 294 tags=9%, list=2%, signal=9% EPO%IOB%EPO EPO%IOB%EPO 51 -0.26176447 -0.82503337 0.8135593 0.85662687 1.0 3270 tags=25%, list=21%, signal=32% PKB-MEDIATED EVENTS%REACTOME DATABASE ID RELEASE 60%109703 PKB-MEDIATED EVENTS%REACTOME DATABASE ID RELEASE 60%109703 35 -0.27932778 -0.82488346 0.77627116 0.85644656 1.0 3651 tags=23%, list=24%, signal=30% AXO-DENDRITIC TRANSPORT%GOBP%GO:0008088 AXO-DENDRITIC TRANSPORT%GOBP%GO:0008088 29 -0.29370335 -0.82438457 0.7411765 0.8568987 1.0 1235 tags=14%, list=8%, signal=15% PYRIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0072524 PYRIDINE-CONTAINING COMPOUND METABOLIC PROCESS%GOBP%GO:0072524 82 -0.24202617 -0.8237622 0.8738739 0.8575206 1.0 3546 tags=28%, list=23%, signal=36% PYRUVATE METABOLISM%REACTOME DATABASE ID RELEASE 60%70268 PYRUVATE METABOLISM%REACTOME DATABASE ID RELEASE 60%70268 22 -0.31479713 -0.8229983 0.73714286 0.85841167 1.0 4865 tags=45%, list=32%, signal=67% BICELLULAR TIGHT JUNCTION ASSEMBLY%GOBP%GO:0070830 BICELLULAR TIGHT JUNCTION ASSEMBLY%GOBP%GO:0070830 25 -0.30888957 -0.8221301 0.7331461 0.8595242 1.0 3210 tags=32%, list=21%, signal=40% SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA 34 -0.28353885 -0.8203258 0.7767296 0.8623208 1.0 3065 tags=24%, list=20%, signal=29% REGULATION OF RESPONSE TO OXIDATIVE STRESS%GOBP%GO:1902882 REGULATION OF RESPONSE TO OXIDATIVE STRESS%GOBP%GO:1902882 48 -0.26560688 -0.82031155 0.76744187 0.8618659 1.0 2423 tags=21%, list=16%, signal=25% T CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002292 T CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002292 17 -0.3400561 -0.81988996 0.7364341 0.86215 1.0 2461 tags=35%, list=16%, signal=42% REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031110 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031110 36 -0.2823197 -0.81975114 0.79672134 0.86193293 1.0 2428 tags=22%, list=16%, signal=26% MRNA CLEAVAGE%GOBP%GO:0006379 MRNA CLEAVAGE%GOBP%GO:0006379 16 -0.34619185 -0.81816 0.70886075 0.8642496 1.0 2233 tags=25%, list=15%, signal=29% REGULATION OF SYNAPTIC VESICLE EXOCYTOSIS%GOBP%GO:2000300 REGULATION OF SYNAPTIC VESICLE EXOCYTOSIS%GOBP%GO:2000300 15 -0.33741385 -0.8171453 0.73544973 0.8656997 1.0 513 tags=7%, list=3%, signal=7% EXCRETION%GOBP%GO:0007588 EXCRETION%GOBP%GO:0007588 25 -0.30224603 -0.81578374 0.76285714 0.8676207 1.0 3996 tags=28%, list=26%, signal=38% TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE%REACTOME%R-HSA-6803204.1 TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE%REACTOME%R-HSA-6803204.1 20 -0.3269743 -0.8155975 0.68393785 0.8674706 1.0 3345 tags=30%, list=22%, signal=38% RECYCLING PATHWAY OF L1%REACTOME DATABASE ID RELEASE 60%437239 RECYCLING PATHWAY OF L1%REACTOME DATABASE ID RELEASE 60%437239 26 -0.3077753 -0.81532764 0.77014923 0.8674701 1.0 927 tags=15%, list=6%, signal=16% PHASE II - CONJUGATION OF COMPOUNDS%REACTOME%R-HSA-156580.2 PHASE II - CONJUGATION OF COMPOUNDS%REACTOME%R-HSA-156580.2 71 -0.23945831 -0.8148624 0.8483412 0.8677908 1.0 3778 tags=37%, list=25%, signal=48% RETROGRADE VESICLE-MEDIATED TRANSPORT, GOLGI TO ER%GOBP%GO:0006890 RETROGRADE VESICLE-MEDIATED TRANSPORT, GOLGI TO ER%GOBP%GO:0006890 76 -0.24099539 -0.81013113 0.885 0.87552 1.0 3609 tags=33%, list=24%, signal=43% POSITIVE REGULATION OF CELL CYCLE G1/S PHASE TRANSITION%GOBP%GO:1902808 POSITIVE REGULATION OF CELL CYCLE G1/S PHASE TRANSITION%GOBP%GO:1902808 20 -0.31552753 -0.8077662 0.7406484 0.87909275 1.0 3835 tags=40%, list=25%, signal=53% NICOTINAMIDE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0046496 NICOTINAMIDE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0046496 74 -0.23813362 -0.80683756 0.92523366 0.8802845 1.0 4765 tags=41%, list=31%, signal=59% PYRIDINE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0019362 PYRIDINE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0019362 74 -0.23813362 -0.8068347 0.877551 0.87980634 1.0 4765 tags=41%, list=31%, signal=59% ST_ERK1_ERK2_MAPK_PATHWAY%MSIGDB_C2%ST_ERK1_ERK2_MAPK_PATHWAY ST_ERK1_ERK2_MAPK_PATHWAY%MSIGDB_C2%ST_ERK1_ERK2_MAPK_PATHWAY 31 -0.28825065 -0.80677086 0.7867868 0.87944776 1.0 3544 tags=32%, list=23%, signal=42% CELLULAR KETONE METABOLIC PROCESS%GOBP%GO:0042180 CELLULAR KETONE METABOLIC PROCESS%GOBP%GO:0042180 38 -0.27367464 -0.80572 0.80921054 0.88075066 1.0 3037 tags=24%, list=20%, signal=30% RAF ACTIVATION%REACTOME%R-HSA-5673000.1 RAF ACTIVATION%REACTOME%R-HSA-5673000.1 24 -0.3046066 -0.8017425 0.78356165 0.8869359 1.0 2252 tags=21%, list=15%, signal=24% GROWTH HORMONE RECEPTOR SIGNALING%REACTOME%R-HSA-982772.1 GROWTH HORMONE RECEPTOR SIGNALING%REACTOME%R-HSA-982772.1 18 -0.32481262 -0.80153054 0.7373494 0.8867869 1.0 1204 tags=22%, list=8%, signal=24% NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS%GOBP%GO:0034249 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS%GOBP%GO:0034249 125 -0.22144468 -0.7988797 0.95 0.89055616 1.0 1449 tags=12%, list=10%, signal=13% IL6%NETPATH%IL6 IL6%NETPATH%IL6 84 -0.22740002 -0.7984068 0.9390863 0.89084965 1.0 2532 tags=15%, list=17%, signal=18% HISTONE LYSINE METHYLATION%GOBP%GO:0034968 HISTONE LYSINE METHYLATION%GOBP%GO:0034968 28 -0.28933898 -0.7974276 0.7807808 0.8919571 1.0 5475 tags=43%, list=36%, signal=67% CD28 DEPENDENT PI3K AKT SIGNALING%REACTOME DATABASE ID RELEASE 60%389357 CD28 DEPENDENT PI3K AKT SIGNALING%REACTOME DATABASE ID RELEASE 60%389357 21 -0.3083286 -0.7962932 0.7681564 0.8932549 1.0 3240 tags=29%, list=21%, signal=36% DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER'S DISEASE MODELS%REACTOME DATABASE ID RELEASE 60%8862803 DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER'S DISEASE MODELS%REACTOME DATABASE ID RELEASE 60%8862803 21 -0.31407675 -0.79613036 0.75652176 0.89304316 1.0 1867 tags=29%, list=12%, signal=33% TRIGLYCERIDE METABOLIC PROCESS%GOBP%GO:0006641 TRIGLYCERIDE METABOLIC PROCESS%GOBP%GO:0006641 29 -0.28910872 -0.79611236 0.809375 0.89258987 1.0 1768 tags=21%, list=12%, signal=23% NEURODEGENERATIVE DISEASES%REACTOME DATABASE ID RELEASE 60%8863678 NEURODEGENERATIVE DISEASES%REACTOME DATABASE ID RELEASE 60%8863678 21 -0.31407675 -0.7960527 0.76441103 0.8922146 1.0 1867 tags=29%, list=12%, signal=33% NEGATIVE REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903312 NEGATIVE REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903312 21 -0.30748576 -0.7959785 0.7566845 0.8918353 1.0 513 tags=10%, list=3%, signal=10% MODULATION OF TRANSCRIPTION IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0052312 MODULATION OF TRANSCRIPTION IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0052312 25 -0.2962481 -0.7923706 0.80588233 0.89700764 1.0 4530 tags=36%, list=30%, signal=51% NUCLEAR ENVELOPE REASSEMBLY%GOBP%GO:0031468 NUCLEAR ENVELOPE REASSEMBLY%GOBP%GO:0031468 17 -0.32342437 -0.7916905 0.7613065 0.8975645 1.0 4701 tags=47%, list=31%, signal=68% HYPOXIA RESPONSE VIA HIF ACTIVATION%PANTHER PATHWAY%P00030 HYPOXIA RESPONSE VIA HIF ACTIVATION%PANTHER PATHWAY%P00030 15 -0.33360696 -0.7910164 0.7432099 0.8981125 1.0 1370 tags=13%, list=9%, signal=15% RAC1 SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%RAC1 SIGNALING PATHWAY RAC1 SIGNALING PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%RAC1 SIGNALING PATHWAY 52 -0.24594383 -0.7903492 0.8592058 0.8986731 1.0 2623 tags=17%, list=17%, signal=21% NEGATIVE REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032205 NEGATIVE REGULATION OF TELOMERE MAINTENANCE%GOBP%GO:0032205 30 -0.28305948 -0.7902549 0.8273973 0.8983315 1.0 1156 tags=13%, list=8%, signal=14% PID_RAC1_PATHWAY%MSIGDB_C2%PID_RAC1_PATHWAY PID_RAC1_PATHWAY%MSIGDB_C2%PID_RAC1_PATHWAY 52 -0.24594377 -0.7895578 0.88235295 0.89889556 1.0 2623 tags=17%, list=17%, signal=21% MODULATION BY HOST OF SYMBIONT TRANSCRIPTION%GOBP%GO:0052472 MODULATION BY HOST OF SYMBIONT TRANSCRIPTION%GOBP%GO:0052472 25 -0.2962481 -0.78871125 0.7994186 0.8997108 1.0 4530 tags=36%, list=30%, signal=51% REGULATION OF RECEPTOR RECYCLING%GOBP%GO:0001919 REGULATION OF RECEPTOR RECYCLING%GOBP%GO:0001919 15 -0.331985 -0.78811127 0.79036146 0.9001707 1.0 1228 tags=20%, list=8%, signal=22% TBC RABGAPS%REACTOME%R-HSA-8854214.1 TBC RABGAPS%REACTOME%R-HSA-8854214.1 43 -0.25665358 -0.7871785 0.85347986 0.90103847 1.0 4820 tags=42%, list=32%, signal=61% MODULATION BY HOST OF VIRAL TRANSCRIPTION%GOBP%GO:0043921 MODULATION BY HOST OF VIRAL TRANSCRIPTION%GOBP%GO:0043921 25 -0.2962481 -0.7863964 0.80759495 0.90176255 1.0 4530 tags=36%, list=30%, signal=51% MYELOID CELL HOMEOSTASIS%GOBP%GO:0002262 MYELOID CELL HOMEOSTASIS%GOBP%GO:0002262 34 -0.27482513 -0.7853867 0.85897434 0.90278226 1.0 1204 tags=15%, list=8%, signal=16% INTRACILIARY TRANSPORT%GOBP%GO:0042073 INTRACILIARY TRANSPORT%GOBP%GO:0042073 40 -0.26112646 -0.7853714 0.8920635 0.9023143 1.0 4421 tags=30%, list=29%, signal=42% FC-GAMMA RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038094 FC-GAMMA RECEPTOR SIGNALING PATHWAY%GOBP%GO:0038094 69 -0.23486768 -0.7844857 0.93273544 0.9031147 1.0 3959 tags=33%, list=26%, signal=45% NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION%GOBP%GO:0045839 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION%GOBP%GO:0045839 24 -0.29369393 -0.7840883 0.7867435 0.9032485 1.0 3593 tags=46%, list=24%, signal=60% IRON UPTAKE AND TRANSPORT%REACTOME DATABASE ID RELEASE 60%917937 IRON UPTAKE AND TRANSPORT%REACTOME DATABASE ID RELEASE 60%917937 54 -0.2505697 -0.78350174 0.88065845 0.90360117 1.0 4666 tags=37%, list=31%, signal=53% NEGATIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002820 NEGATIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE%GOBP%GO:0002820 17 -0.31231388 -0.7821705 0.79373366 0.90512854 1.0 3885 tags=59%, list=26%, signal=79% POSITIVE REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031058 POSITIVE REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031058 57 -0.23818623 -0.78113383 0.91699606 0.906187 1.0 4719 tags=35%, list=31%, signal=51% CELLULAR MONOVALENT INORGANIC CATION HOMEOSTASIS%GOBP%GO:0030004 CELLULAR MONOVALENT INORGANIC CATION HOMEOSTASIS%GOBP%GO:0030004 74 -0.23404351 -0.7805843 0.9366516 0.906479 1.0 2566 tags=18%, list=17%, signal=21% COBALAMIN (CBL, VITAMIN B12) TRANSPORT AND METABOLISM%REACTOME%R-HSA-196741.2 COBALAMIN (CBL, VITAMIN B12) TRANSPORT AND METABOLISM%REACTOME%R-HSA-196741.2 16 -0.32626528 -0.7796462 0.7736842 0.9072924 1.0 4171 tags=44%, list=27%, signal=60% EARLY ENDOSOME TO LATE ENDOSOME TRANSPORT%GOBP%GO:0045022 EARLY ENDOSOME TO LATE ENDOSOME TRANSPORT%GOBP%GO:0045022 17 -0.32401168 -0.7795412 0.7719298 0.90693915 1.0 6242 tags=47%, list=41%, signal=80% CELLULAR SENESCENCE%GOBP%GO:0090398 CELLULAR SENESCENCE%GOBP%GO:0090398 25 -0.29714864 -0.7793356 0.7752809 0.90675753 1.0 2779 tags=28%, list=18%, signal=34% MYD88-DEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002755 MYD88-DEPENDENT TOLL-LIKE RECEPTOR SIGNALING PATHWAY%GOBP%GO:0002755 28 -0.27927604 -0.77783215 0.8493976 0.9084913 1.0 4440 tags=39%, list=29%, signal=55% ALPHA-SYNUCLEIN SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ALPHA-SYNUCLEIN SIGNALING ALPHA-SYNUCLEIN SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ALPHA-SYNUCLEIN SIGNALING 27 -0.2790131 -0.77759975 0.8443804 0.90832794 1.0 4315 tags=41%, list=28%, signal=57% REGULATION OF B CELL MEDIATED IMMUNITY%GOBP%GO:0002712 REGULATION OF B CELL MEDIATED IMMUNITY%GOBP%GO:0002712 18 -0.3166632 -0.77537143 0.76943004 0.9109892 1.0 1826 tags=28%, list=12%, signal=32% PROTEIN TRANSPORT ALONG MICROTUBULE%GOBP%GO:0098840 PROTEIN TRANSPORT ALONG MICROTUBULE%GOBP%GO:0098840 41 -0.2588167 -0.77525896 0.8939394 0.9106632 1.0 4589 tags=32%, list=30%, signal=45% MICROTUBULE-BASED PROTEIN TRANSPORT%GOBP%GO:0099118 MICROTUBULE-BASED PROTEIN TRANSPORT%GOBP%GO:0099118 41 -0.2588167 -0.77520376 0.8942308 0.9102476 1.0 4589 tags=32%, list=30%, signal=45% ENTRY INTO HOST CELL%GOBP%GO:0030260 ENTRY INTO HOST CELL%GOBP%GO:0030260 36 -0.26251483 -0.7738669 0.8694158 0.9116607 1.0 2643 tags=22%, list=17%, signal=27% INTRACILIARY TRANSPORT INVOLVED IN CILIUM ASSEMBLY%GOBP%GO:0035735 INTRACILIARY TRANSPORT INVOLVED IN CILIUM ASSEMBLY%GOBP%GO:0035735 36 -0.26028818 -0.77112335 0.8761905 0.915012 1.0 1922 tags=14%, list=13%, signal=16% REGULATION OF ACTIN DYNAMICS FOR PHAGOCYTIC CUP FORMATION%REACTOME%R-HSA-2029482.2 REGULATION OF ACTIN DYNAMICS FOR PHAGOCYTIC CUP FORMATION%REACTOME%R-HSA-2029482.2 56 -0.23484713 -0.7701124 0.9234043 0.9159379 1.0 3959 tags=36%, list=26%, signal=48% FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS 29 -0.27031025 -0.7681315 0.85670733 0.9181904 1.0 3033 tags=28%, list=20%, signal=34% REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031056 REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031056 86 -0.22409484 -0.7662779 0.96666664 0.92016554 1.0 3103 tags=20%, list=20%, signal=25% ENTRY INTO HOST%GOBP%GO:0044409 ENTRY INTO HOST%GOBP%GO:0044409 36 -0.26251483 -0.76601565 0.8794788 0.9200377 1.0 2643 tags=22%, list=17%, signal=27% IL9%NETPATH%IL9 IL9%NETPATH%IL9 22 -0.29885226 -0.76414883 0.82848835 0.9220402 1.0 2486 tags=23%, list=16%, signal=27% B CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002312 B CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002312 19 -0.29770046 -0.76297873 0.8051948 0.9230719 1.0 2195 tags=21%, list=14%, signal=25% ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051806 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051806 36 -0.26251483 -0.7628381 0.83450705 0.9227909 1.0 2643 tags=22%, list=17%, signal=27% BIOCARTA_MPR_PATHWAY%MSIGDB_C2%BIOCARTA_MPR_PATHWAY BIOCARTA_MPR_PATHWAY%MSIGDB_C2%BIOCARTA_MPR_PATHWAY 31 -0.2648004 -0.76267755 0.8802817 0.92251825 1.0 3733 tags=29%, list=25%, signal=38% MAP3K8 (TPL2)-DEPENDENT MAPK1 3 ACTIVATION%REACTOME%R-HSA-5684264.2 MAP3K8 (TPL2)-DEPENDENT MAPK1 3 ACTIVATION%REACTOME%R-HSA-5684264.2 16 -0.31819296 -0.7624467 0.783715 0.92231655 1.0 4440 tags=38%, list=29%, signal=53% ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA%REACTOME DATABASE ID RELEASE 60%111447 ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA%REACTOME DATABASE ID RELEASE 60%111447 15 -0.3154307 -0.7621655 0.8080808 0.92218256 1.0 2172 tags=20%, list=14%, signal=23% BIOCARTA_ARF_PATHWAY%MSIGDB_C2%BIOCARTA_ARF_PATHWAY BIOCARTA_ARF_PATHWAY%MSIGDB_C2%BIOCARTA_ARF_PATHWAY 17 -0.31046608 -0.7619393 0.80145276 0.9219976 1.0 1870 tags=24%, list=12%, signal=27% REGULATION OF VOLTAGE-GATED CALCIUM CHANNEL ACTIVITY%GOBP%GO:1901385 REGULATION OF VOLTAGE-GATED CALCIUM CHANNEL ACTIVITY%GOBP%GO:1901385 18 -0.302665 -0.76137686 0.8131868 0.92225176 1.0 513 tags=11%, list=3%, signal=11% REGULATION OF MRNA CATABOLIC PROCESS%GOBP%GO:0061013 REGULATION OF MRNA CATABOLIC PROCESS%GOBP%GO:0061013 27 -0.27554247 -0.7598396 0.8484042 0.92368186 1.0 1545 tags=11%, list=10%, signal=12% RESPONSE TO ZINC ION%GOBP%GO:0010043 RESPONSE TO ZINC ION%GOBP%GO:0010043 20 -0.3053698 -0.7590895 0.83923703 0.92417663 1.0 5841 tags=40%, list=38%, signal=65% MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051817 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051817 75 -0.22300671 -0.75851226 0.966805 0.9244333 1.0 3737 tags=25%, list=25%, signal=33% REGULATION OF CHOLESTEROL BIOSYNTHETIC PROCESS%GOBP%GO:0045540 REGULATION OF CHOLESTEROL BIOSYNTHETIC PROCESS%GOBP%GO:0045540 39 -0.25470313 -0.7584366 0.90614885 0.92405146 1.0 1328 tags=13%, list=9%, signal=14% L-AMINO ACID TRANSPORT%GOBP%GO:0015807 L-AMINO ACID TRANSPORT%GOBP%GO:0015807 22 -0.27934045 -0.7578509 0.8495822 0.9243132 1.0 1771 tags=14%, list=12%, signal=15% COBALAMIN METABOLIC PROCESS%GOBP%GO:0009235 COBALAMIN METABOLIC PROCESS%GOBP%GO:0009235 16 -0.32626528 -0.75772196 0.78028166 0.923988 1.0 4171 tags=44%, list=27%, signal=60% PID_HNF3B_PATHWAY%MSIGDB_C2%PID_HNF3B_PATHWAY PID_HNF3B_PATHWAY%MSIGDB_C2%PID_HNF3B_PATHWAY 30 -0.26302144 -0.7573325 0.88161993 0.9239743 1.0 3033 tags=27%, list=20%, signal=33% VESICLE TRANSPORT ALONG MICROTUBULE%GOBP%GO:0047496 VESICLE TRANSPORT ALONG MICROTUBULE%GOBP%GO:0047496 23 -0.29190987 -0.7559894 0.8455285 0.9251731 1.0 1235 tags=13%, list=8%, signal=14% CD209 (DC-SIGN) SIGNALING%REACTOME%R-HSA-5621575.1 CD209 (DC-SIGN) SIGNALING%REACTOME%R-HSA-5621575.1 19 -0.30010656 -0.7538739 0.8296703 0.9272323 1.0 2857 tags=37%, list=19%, signal=45% PROTEIN PALMITOYLATION%GOBP%GO:0018345 PROTEIN PALMITOYLATION%GOBP%GO:0018345 20 -0.29872698 -0.75253314 0.84313726 0.9283363 1.0 2384 tags=20%, list=16%, signal=24% STEROID BIOSYNTHETIC PROCESS%GOBP%GO:0006694 STEROID BIOSYNTHETIC PROCESS%GOBP%GO:0006694 84 -0.2202881 -0.7523668 0.9727273 0.9280443 1.0 2821 tags=20%, list=19%, signal=25% ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051828 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION%GOBP%GO:0051828 36 -0.26251483 -0.7518298 0.90460527 0.92822194 1.0 2643 tags=22%, list=17%, signal=27% MEMBRANE LIPID BIOSYNTHETIC PROCESS%GOBP%GO:0046467 MEMBRANE LIPID BIOSYNTHETIC PROCESS%GOBP%GO:0046467 80 -0.2161637 -0.7504264 0.9362745 0.9294419 1.0 2122 tags=15%, list=14%, signal=17% BIOCARTA_EIF_PATHWAY%MSIGDB_C2%BIOCARTA_EIF_PATHWAY BIOCARTA_EIF_PATHWAY%MSIGDB_C2%BIOCARTA_EIF_PATHWAY 16 -0.3097359 -0.7498148 0.82758623 0.92968553 1.0 3176 tags=31%, list=21%, signal=39% MEMBRANE PROTEIN INTRACELLULAR DOMAIN PROTEOLYSIS%GOBP%GO:0031293 MEMBRANE PROTEIN INTRACELLULAR DOMAIN PROTEOLYSIS%GOBP%GO:0031293 16 -0.30935377 -0.74945575 0.8004866 0.92959267 1.0 3174 tags=31%, list=21%, signal=39% HISTONE H3-K4 METHYLATION%GOBP%GO:0051568 HISTONE H3-K4 METHYLATION%GOBP%GO:0051568 18 -0.29850122 -0.74568653 0.8469657 0.93361884 1.0 3023 tags=22%, list=20%, signal=28% REGULATION OF TOR SIGNALING%GOBP%GO:0032006 REGULATION OF TOR SIGNALING%GOBP%GO:0032006 69 -0.22311857 -0.74539953 0.9596413 0.9334777 1.0 3418 tags=23%, list=22%, signal=30% SPERMATID DEVELOPMENT%GOBP%GO:0007286 SPERMATID DEVELOPMENT%GOBP%GO:0007286 36 -0.2537926 -0.74209815 0.89285713 0.9367676 1.0 2113 tags=17%, list=14%, signal=19% INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR%GOBP%GO:0042771 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR%GOBP%GO:0042771 17 -0.30392662 -0.74164975 0.8399015 0.93678564 1.0 1012 tags=12%, list=7%, signal=13% NADH METABOLIC PROCESS%GOBP%GO:0006734 NADH METABOLIC PROCESS%GOBP%GO:0006734 25 -0.27072325 -0.7383016 0.85833335 0.93996567 1.0 4233 tags=32%, list=28%, signal=44% PID_ARF6_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_ARF6_DOWNSTREAM_PATHWAY PID_ARF6_DOWNSTREAM_PATHWAY%MSIGDB_C2%PID_ARF6_DOWNSTREAM_PATHWAY 15 -0.3083338 -0.73821306 0.8065327 0.93957496 1.0 3848 tags=40%, list=25%, signal=53% ORGANIC HYDROXY COMPOUND CATABOLIC PROCESS%GOBP%GO:1901616 ORGANIC HYDROXY COMPOUND CATABOLIC PROCESS%GOBP%GO:1901616 29 -0.2635906 -0.73774165 0.898773 0.9395902 1.0 3702 tags=34%, list=24%, signal=45% REGULATION OF HISTONE ACETYLATION%GOBP%GO:0035065 REGULATION OF HISTONE ACETYLATION%GOBP%GO:0035065 38 -0.2532894 -0.73738045 0.90625 0.93949854 1.0 4403 tags=37%, list=29%, signal=52% BIOCARTA_MTOR_PATHWAY%MSIGDB_C2%BIOCARTA_MTOR_PATHWAY BIOCARTA_MTOR_PATHWAY%MSIGDB_C2%BIOCARTA_MTOR_PATHWAY 23 -0.27755708 -0.7355067 0.84679663 0.9410282 1.0 3007 tags=22%, list=20%, signal=27% FC-GAMMA RECEPTOR SIGNALING PATHWAY INVOLVED IN PHAGOCYTOSIS%GOBP%GO:0038096 FC-GAMMA RECEPTOR SIGNALING PATHWAY INVOLVED IN PHAGOCYTOSIS%GOBP%GO:0038096 68 -0.21553972 -0.7341982 0.97321427 0.94189376 1.0 3959 tags=32%, list=26%, signal=44% REGULATION OF HISTONE METHYLATION%GOBP%GO:0031060 REGULATION OF HISTONE METHYLATION%GOBP%GO:0031060 33 -0.24877052 -0.7299647 0.90460527 0.94574934 1.0 3103 tags=18%, list=20%, signal=23% AFLATOXIN ACTIVATION AND DETOXIFICATION%REACTOME%R-HSA-5423646.2 AFLATOXIN ACTIVATION AND DETOXIFICATION%REACTOME%R-HSA-5423646.2 16 -0.30368006 -0.7290513 0.8630807 0.94621354 1.0 3141 tags=38%, list=21%, signal=47% POSITIVE REGULATION OF CELL DIVISION%GOBP%GO:0051781 POSITIVE REGULATION OF CELL DIVISION%GOBP%GO:0051781 28 -0.2603406 -0.72847927 0.90993786 0.9462872 1.0 4083 tags=36%, list=27%, signal=49% NAD METABOLIC PROCESS%GOBP%GO:0019674 NAD METABOLIC PROCESS%GOBP%GO:0019674 48 -0.2346488 -0.72518057 0.9417808 0.94909716 1.0 4544 tags=42%, list=30%, signal=59% NEGATIVE REGULATION OF PROTEIN DEPOLYMERIZATION%GOBP%GO:1901880 NEGATIVE REGULATION OF PROTEIN DEPOLYMERIZATION%GOBP%GO:1901880 22 -0.27615562 -0.72015965 0.88481677 0.9535117 1.0 2278 tags=23%, list=15%, signal=27% ARF6 DOWNSTREAM PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ARF6 DOWNSTREAM PATHWAY ARF6 DOWNSTREAM PATHWAY%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ARF6 DOWNSTREAM PATHWAY 15 -0.30833375 -0.7196194 0.84514433 0.95358944 1.0 3848 tags=40%, list=25%, signal=53% IMMUNE RESPONSE-REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN PHAGOCYTOSIS%GOBP%GO:0002433 IMMUNE RESPONSE-REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN PHAGOCYTOSIS%GOBP%GO:0002433 68 -0.21553972 -0.7195728 0.98678416 0.9531359 1.0 3959 tags=32%, list=26%, signal=44% INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:0070059 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS%GOBP%GO:0070059 20 -0.28655404 -0.7177441 0.8658228 0.95435333 1.0 1310 tags=15%, list=9%, signal=16% NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043242 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY%GOBP%GO:0043242 25 -0.265061 -0.7172359 0.8995098 0.95430064 1.0 2278 tags=20%, list=15%, signal=23% MAP KINASE ACTIVATION IN TLR CASCADE%REACTOME DATABASE ID RELEASE 60%450294 MAP KINASE ACTIVATION IN TLR CASCADE%REACTOME DATABASE ID RELEASE 60%450294 63 -0.21920013 -0.715055 0.9669118 0.95582175 1.0 2378 tags=19%, list=16%, signal=22% REGULATION OF DNA-TEMPLATED TRANSCRIPTION, INITIATION%GOBP%GO:2000142 REGULATION OF DNA-TEMPLATED TRANSCRIPTION, INITIATION%GOBP%GO:2000142 28 -0.2557843 -0.7121149 0.9059561 0.95798814 1.0 3181 tags=29%, list=21%, signal=36% 3-PHOSPHOINOSITIDE DEGRADATION%HUMANCYC%PWY-6368 3-PHOSPHOINOSITIDE DEGRADATION%HUMANCYC%PWY-6368 19 -0.28044796 -0.71183264 0.88753057 0.95773953 1.0 1568 tags=16%, list=10%, signal=18% HISTONE DEUBIQUITINATION%GOBP%GO:0016578 HISTONE DEUBIQUITINATION%GOBP%GO:0016578 21 -0.27681288 -0.71042687 0.8611898 0.95852035 1.0 2479 tags=14%, list=16%, signal=17% REGULATION OF CHOLESTEROL METABOLIC PROCESS%GOBP%GO:0090181 REGULATION OF CHOLESTEROL METABOLIC PROCESS%GOBP%GO:0090181 44 -0.23488583 -0.70883363 0.9411765 0.95940566 1.0 1328 tags=11%, list=9%, signal=12% HISTONE MRNA CATABOLIC PROCESS%GOBP%GO:0071044 HISTONE MRNA CATABOLIC PROCESS%GOBP%GO:0071044 15 -0.293595 -0.7061149 0.88106793 0.96121967 1.0 3812 tags=27%, list=25%, signal=36% PROTEIN DEGLYCOSYLATION%GOBP%GO:0006517 PROTEIN DEGLYCOSYLATION%GOBP%GO:0006517 33 -0.2431094 -0.7058931 0.925816 0.9608983 1.0 3518 tags=24%, list=23%, signal=31% MONOVALENT INORGANIC CATION HOMEOSTASIS%GOBP%GO:0055067 MONOVALENT INORGANIC CATION HOMEOSTASIS%GOBP%GO:0055067 83 -0.20680612 -0.7036902 1.0 0.96223325 1.0 2566 tags=16%, list=17%, signal=19% MODULATION BY HOST OF VIRAL PROCESS%GOBP%GO:0044788 MODULATION BY HOST OF VIRAL PROCESS%GOBP%GO:0044788 18 -0.28113136 -0.70131767 0.88082904 0.96358335 1.0 1328 tags=11%, list=9%, signal=12% NEGATIVE REGULATION OF MET ACTIVITY%REACTOME DATABASE ID RELEASE 60%6807004 NEGATIVE REGULATION OF MET ACTIVITY%REACTOME DATABASE ID RELEASE 60%6807004 20 -0.2771254 -0.70078546 0.8922652 0.96351665 1.0 873 tags=10%, list=6%, signal=11% HISTONE METHYLATION%GOBP%GO:0016571 HISTONE METHYLATION%GOBP%GO:0016571 40 -0.23550138 -0.69919395 0.96 0.964303 1.0 3326 tags=20%, list=22%, signal=26% TOR SIGNALING%GOBP%GO:0031929 TOR SIGNALING%GOBP%GO:0031929 20 -0.27741897 -0.6981969 0.898017 0.9645875 1.0 2132 tags=15%, list=14%, signal=17% REGULATION OF PROTEIN EXIT FROM ENDOPLASMIC RETICULUM%GOBP%GO:0070861 REGULATION OF PROTEIN EXIT FROM ENDOPLASMIC RETICULUM%GOBP%GO:0070861 18 -0.27711123 -0.6977509 0.88664985 0.9644226 1.0 3486 tags=22%, list=23%, signal=29% POSITIVE REGULATION OF MICROTUBULE POLYMERIZATION%GOBP%GO:0031116 POSITIVE REGULATION OF MICROTUBULE POLYMERIZATION%GOBP%GO:0031116 16 -0.28965527 -0.6973017 0.89113927 0.9643107 1.0 793 tags=13%, list=5%, signal=13% POSITIVE REGULATION OF MRNA CATABOLIC PROCESS%GOBP%GO:0061014 POSITIVE REGULATION OF MRNA CATABOLIC PROCESS%GOBP%GO:0061014 22 -0.26697648 -0.6959961 0.91812867 0.96482265 1.0 1545 tags=9%, list=10%, signal=10% NUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009132 NUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS%GOBP%GO:0009132 38 -0.23494472 -0.6900886 0.95714283 0.96886396 1.0 4233 tags=29%, list=28%, signal=40% SERINE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009069 SERINE FAMILY AMINO ACID METABOLIC PROCESS%GOBP%GO:0009069 28 -0.24508719 -0.68767005 0.942029 0.9701889 1.0 6248 tags=61%, list=41%, signal=103% NEGATIVE REGULATION OF PROTEIN DEPHOSPHORYLATION%GOBP%GO:0035308 NEGATIVE REGULATION OF PROTEIN DEPHOSPHORYLATION%GOBP%GO:0035308 21 -0.2692861 -0.68683034 0.9050132 0.9702806 1.0 1634 tags=19%, list=11%, signal=21% REGULATION OF SYNAPTIC VESICLE TRANSPORT%GOBP%GO:1902803 REGULATION OF SYNAPTIC VESICLE TRANSPORT%GOBP%GO:1902803 20 -0.27180004 -0.6848682 0.912 0.97112256 1.0 513 tags=5%, list=3%, signal=5% SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS%REACTOME%R-HSA-1839117.2 SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS%REACTOME%R-HSA-1839117.2 16 -0.2805212 -0.68010664 0.9061728 0.97380435 1.0 71 tags=6%, list=0%, signal=6% HISTONE H4 ACETYLATION%GOBP%GO:0043967 HISTONE H4 ACETYLATION%GOBP%GO:0043967 35 -0.23502761 -0.6781032 0.9741936 0.9746205 1.0 5845 tags=51%, list=38%, signal=83% ENDOSOME ORGANIZATION%GOBP%GO:0007032 ENDOSOME ORGANIZATION%GOBP%GO:0007032 59 -0.2046412 -0.67050415 0.984252 0.9787901 1.0 3946 tags=27%, list=26%, signal=36% POSITIVE REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031112 POSITIVE REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0031112 18 -0.2662376 -0.6681119 0.9127182 0.97971225 1.0 793 tags=11%, list=5%, signal=12% GERM CELL DEVELOPMENT%GOBP%GO:0007281 GERM CELL DEVELOPMENT%GOBP%GO:0007281 51 -0.21119153 -0.6677197 0.98841697 0.9794828 1.0 2755 tags=18%, list=18%, signal=21% CELLULAR RESPONSE TO CADMIUM ION%GOBP%GO:0071276 CELLULAR RESPONSE TO CADMIUM ION%GOBP%GO:0071276 22 -0.25341436 -0.66333073 0.94502616 0.9815854 1.0 5055 tags=36%, list=33%, signal=54% RESPONSE TO CADMIUM ION%GOBP%GO:0046686 RESPONSE TO CADMIUM ION%GOBP%GO:0046686 23 -0.2533194 -0.66252536 0.94586897 0.9815351 1.0 5055 tags=35%, list=33%, signal=52% PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS%GOBP%GO:0006661 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS%GOBP%GO:0006661 99 -0.18635188 -0.6611858 1.0 0.981773 1.0 4700 tags=29%, list=31%, signal=42% POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0046827 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0046827 15 -0.28154033 -0.66067016 0.9046455 0.9815525 1.0 5633 tags=47%, list=37%, signal=74% REGULATION OF IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE%GOBP%GO:0002889 REGULATION OF IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE%GOBP%GO:0002889 17 -0.27421373 -0.6586205 0.91122717 0.98221576 1.0 1826 tags=24%, list=12%, signal=27% TRP CHANNELS%REACTOME DATABASE ID RELEASE 60%3295583 TRP CHANNELS%REACTOME DATABASE ID RELEASE 60%3295583 15 -0.27950728 -0.6579218 0.9061033 0.9820836 1.0 1894 tags=13%, list=12%, signal=15% REGULATION OF SYNAPTIC VESICLE CYCLE%GOBP%GO:0098693 REGULATION OF SYNAPTIC VESICLE CYCLE%GOBP%GO:0098693 19 -0.26626754 -0.6576941 0.92419827 0.981693 1.0 513 tags=5%, list=3%, signal=5% ACTIN POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0008154 ACTIN POLYMERIZATION OR DEPOLYMERIZATION%GOBP%GO:0008154 28 -0.23474504 -0.6533094 0.9587021 0.9835581 1.0 2257 tags=18%, list=15%, signal=21% NADP METABOLIC PROCESS%GOBP%GO:0006739 NADP METABOLIC PROCESS%GOBP%GO:0006739 19 -0.26153928 -0.6513058 0.9317585 0.98409796 1.0 6392 tags=68%, list=42%, signal=118% POSITIVE REGULATION OF VACUOLE ORGANIZATION%GOBP%GO:0044090 POSITIVE REGULATION OF VACUOLE ORGANIZATION%GOBP%GO:0044090 15 -0.27309987 -0.65050083 0.9239905 0.9840064 1.0 4507 tags=33%, list=30%, signal=47% VIRAL GENOME REPLICATION%GOBP%GO:0019079 VIRAL GENOME REPLICATION%GOBP%GO:0019079 22 -0.250274 -0.6499895 0.93147206 0.9837796 1.0 4332 tags=27%, list=28%, signal=38% PEPTIDYL-LYSINE METHYLATION%GOBP%GO:0018022 PEPTIDYL-LYSINE METHYLATION%GOBP%GO:0018022 35 -0.2238198 -0.6489215 0.9836066 0.9837963 1.0 5475 tags=40%, list=36%, signal=62% REGULATION OF SULFUR METABOLIC PROCESS%GOBP%GO:0042762 REGULATION OF SULFUR METABOLIC PROCESS%GOBP%GO:0042762 15 -0.27713168 -0.64799803 0.9402985 0.9837489 1.0 4966 tags=47%, list=33%, signal=69% PEPTIDYL-GLUTAMIC ACID MODIFICATION%GOBP%GO:0018200 PEPTIDYL-GLUTAMIC ACID MODIFICATION%GOBP%GO:0018200 20 -0.25118157 -0.64299965 0.94763094 0.985658 1.0 483 tags=5%, list=3%, signal=5% POSITIVE REGULATION OF G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:1900087 POSITIVE REGULATION OF G1/S TRANSITION OF MITOTIC CELL CYCLE%GOBP%GO:1900087 16 -0.2703761 -0.6396472 0.94210523 0.9867285 1.0 3414 tags=31%, list=22%, signal=40% REGULATION OF VACUOLE ORGANIZATION%GOBP%GO:0044088 REGULATION OF VACUOLE ORGANIZATION%GOBP%GO:0044088 42 -0.2148442 -0.63211495 0.9815498 0.9894115 1.0 3946 tags=31%, list=26%, signal=42% PHOSPHATIDYLETHANOLAMINE METABOLIC PROCESS%GOBP%GO:0046337 PHOSPHATIDYLETHANOLAMINE METABOLIC PROCESS%GOBP%GO:0046337 15 -0.2652286 -0.6307733 0.9514563 0.9894695 1.0 1454 tags=13%, list=10%, signal=15% RHO GTPASES ACTIVATE WASPS AND WAVES%REACTOME DATABASE ID RELEASE 60%5663213 RHO GTPASES ACTIVATE WASPS AND WAVES%REACTOME DATABASE ID RELEASE 60%5663213 34 -0.21949236 -0.6291047 0.97306395 0.98966014 1.0 3959 tags=29%, list=26%, signal=40% REGULATION OF ERAD PATHWAY%GOBP%GO:1904292 REGULATION OF ERAD PATHWAY%GOBP%GO:1904292 24 -0.2339822 -0.6269943 0.9608355 0.9899524 1.0 3650 tags=29%, list=24%, signal=38% NEGATIVE REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031057 NEGATIVE REGULATION OF HISTONE MODIFICATION%GOBP%GO:0031057 27 -0.22582264 -0.62680125 0.9695122 0.9895209 1.0 2668 tags=19%, list=18%, signal=22% MISCELLANEOUS TRANSPORT AND BINDING EVENTS%REACTOME%R-HSA-5223345.3 MISCELLANEOUS TRANSPORT AND BINDING EVENTS%REACTOME%R-HSA-5223345.3 21 -0.24932624 -0.6241295 0.95316803 0.9900416 1.0 3897 tags=24%, list=26%, signal=32% PID_IL3_PATHWAY%MSIGDB_C2%PID_IL3_PATHWAY PID_IL3_PATHWAY%MSIGDB_C2%PID_IL3_PATHWAY 25 -0.22420023 -0.6205514 0.98255813 0.9908796 1.0 4346 tags=32%, list=29%, signal=45% GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE%REACTOME DATABASE ID RELEASE 60%210500 GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE%REACTOME DATABASE ID RELEASE 60%210500 18 -0.25051963 -0.615938 0.95189875 0.9920019 1.0 2653 tags=11%, list=17%, signal=13% PEPTIDE CATABOLIC PROCESS%GOBP%GO:0043171 PEPTIDE CATABOLIC PROCESS%GOBP%GO:0043171 22 -0.2364258 -0.6148243 0.96348315 0.991858 1.0 3285 tags=18%, list=22%, signal=23% POSITIVE REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903313 POSITIVE REGULATION OF MRNA METABOLIC PROCESS%GOBP%GO:1903313 33 -0.21185337 -0.614734 0.9844237 0.99139225 1.0 6167 tags=36%, list=41%, signal=61% CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-901042.2 CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-901042.2 26 -0.22963415 -0.61412597 0.9887324 0.9910856 1.0 4440 tags=27%, list=29%, signal=38% ENDOPLASMIC RETICULUM MANNOSE TRIMMING%GOBP%GO:1904380 ENDOPLASMIC RETICULUM MANNOSE TRIMMING%GOBP%GO:1904380 19 -0.24363038 -0.6106265 0.9557292 0.99173176 1.0 4440 tags=32%, list=29%, signal=45% GLUTAMATE SECRETION%GOBP%GO:0014047 GLUTAMATE SECRETION%GOBP%GO:0014047 19 -0.2450225 -0.6071182 0.9713604 0.99229944 1.0 2653 tags=11%, list=17%, signal=13% DNA METHYLATION OR DEMETHYLATION%GOBP%GO:0044728 DNA METHYLATION OR DEMETHYLATION%GOBP%GO:0044728 34 -0.21040124 -0.60593486 0.98447204 0.99219835 1.0 1272 tags=12%, list=8%, signal=13% BIOCARTA_CHREBP2_PATHWAY%MSIGDB_C2%BIOCARTA_CHREBP2_PATHWAY BIOCARTA_CHREBP2_PATHWAY%MSIGDB_C2%BIOCARTA_CHREBP2_PATHWAY 39 -0.20135713 -0.6048456 0.9855596 0.9919981 1.0 5212 tags=31%, list=34%, signal=47% MITOTIC G2/M TRANSITION CHECKPOINT%GOBP%GO:0044818 MITOTIC G2/M TRANSITION CHECKPOINT%GOBP%GO:0044818 17 -0.24601081 -0.6013611 0.9511568 0.99252474 1.0 2804 tags=24%, list=18%, signal=29% SULFUR AMINO ACID METABOLIC PROCESS%GOBP%GO:0000096 SULFUR AMINO ACID METABOLIC PROCESS%GOBP%GO:0000096 30 -0.21449718 -0.5977306 0.97839504 0.99302834 1.0 5214 tags=50%, list=34%, signal=76% REGULATION OF HISTONE DEACETYLATION%GOBP%GO:0031063 REGULATION OF HISTONE DEACETYLATION%GOBP%GO:0031063 15 -0.25270376 -0.596519 0.95238096 0.99287033 1.0 5658 tags=40%, list=37%, signal=64% FORMATION OF SENESCENCE-ASSOCIATED HETEROCHROMATIN FOCI (SAHF)%REACTOME%R-HSA-2559584.1 FORMATION OF SENESCENCE-ASSOCIATED HETEROCHROMATIN FOCI (SAHF)%REACTOME%R-HSA-2559584.1 15 -0.24965455 -0.59545034 0.95843524 0.9926613 1.0 3236 tags=27%, list=21%, signal=34% ACTIVATION OF GENE EXPRESSION BY SREBF (SREBP)%REACTOME DATABASE ID RELEASE 60%2426168 ACTIVATION OF GENE EXPRESSION BY SREBF (SREBP)%REACTOME DATABASE ID RELEASE 60%2426168 38 -0.20145696 -0.58491063 0.9930314 0.99485755 1.0 1242 tags=8%, list=8%, signal=9% ENDOSOME TO LYSOSOME TRANSPORT%GOBP%GO:0008333 ENDOSOME TO LYSOSOME TRANSPORT%GOBP%GO:0008333 34 -0.19926861 -0.58142436 0.983871 0.99519306 1.0 3780 tags=24%, list=25%, signal=31% REGULATION OF PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0046825 REGULATION OF PROTEIN EXPORT FROM NUCLEUS%GOBP%GO:0046825 27 -0.21175884 -0.5745463 0.9811912 0.99614924 1.0 3518 tags=22%, list=23%, signal=29% REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION%REACTOME%R-HSA-6804758.2 REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION%REACTOME%R-HSA-6804758.2 29 -0.20584217 -0.5714317 0.984326 0.9962553 1.0 4507 tags=31%, list=30%, signal=44% ENERGY DEPENDENT REGULATION OF MTOR BY LKB1-AMPK%REACTOME%R-HSA-380972.1 ENERGY DEPENDENT REGULATION OF MTOR BY LKB1-AMPK%REACTOME%R-HSA-380972.1 23 -0.21656172 -0.56638074 0.9819277 0.9966887 1.0 3651 tags=22%, list=24%, signal=29% ER QUALITY CONTROL COMPARTMENT (ERQC)%REACTOME DATABASE ID RELEASE 60%901032 ER QUALITY CONTROL COMPARTMENT (ERQC)%REACTOME DATABASE ID RELEASE 60%901032 21 -0.21686141 -0.56315726 0.9946524 0.99673337 1.0 4440 tags=29%, list=29%, signal=40% IL3-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL3-MEDIATED SIGNALING EVENTS IL3-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%IL3-MEDIATED SIGNALING EVENTS 24 -0.20817335 -0.55630076 0.994382 0.9973809 1.0 4346 tags=29%, list=29%, signal=41% REGULATION OF COFACTOR METABOLIC PROCESS%GOBP%GO:0051193 REGULATION OF COFACTOR METABOLIC PROCESS%GOBP%GO:0051193 38 -0.1853067 -0.5544298 0.996875 0.99719214 1.0 4912 tags=37%, list=32%, signal=54% GLYCOLYSIS%PANTHER PATHWAY%P00024 GLYCOLYSIS%PANTHER PATHWAY%P00024 15 -0.23123363 -0.5504491 0.9769821 0.9972794 1.0 3546 tags=20%, list=23%, signal=26% ACID SECRETION%GOBP%GO:0046717 ACID SECRETION%GOBP%GO:0046717 27 -0.2009659 -0.54859114 0.9943343 0.9970607 1.0 3477 tags=15%, list=23%, signal=19% TRANSFERRIN TRANSPORT%GOBP%GO:0033572 TRANSFERRIN TRANSPORT%GOBP%GO:0033572 33 -0.19168091 -0.54767364 0.996904 0.99668 1.0 4520 tags=27%, list=30%, signal=39% TRIVALENT INORGANIC CATION TRANSPORT%GOBP%GO:0072512 TRIVALENT INORGANIC CATION TRANSPORT%GOBP%GO:0072512 33 -0.19168091 -0.54737043 0.99378884 0.996222 1.0 4520 tags=27%, list=30%, signal=39% REGULATION OF COENZYME METABOLIC PROCESS%GOBP%GO:0051196 REGULATION OF COENZYME METABOLIC PROCESS%GOBP%GO:0051196 38 -0.1853067 -0.5404157 0.99658704 0.99667877 1.0 4912 tags=37%, list=32%, signal=54% REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2 3 SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2 3 SIGNALING REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2 3 SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2 3 SIGNALING 19 -0.21807523 -0.5399012 0.98687667 0.9962307 1.0 5355 tags=32%, list=35%, signal=49% FERRIC IRON TRANSPORT%GOBP%GO:0015682 FERRIC IRON TRANSPORT%GOBP%GO:0015682 33 -0.19168091 -0.53834325 0.99376947 0.9959275 1.0 4520 tags=27%, list=30%, signal=39% GLUTAMATE METABOLIC PROCESS%GOBP%GO:0006536 GLUTAMATE METABOLIC PROCESS%GOBP%GO:0006536 18 -0.21830072 -0.53660023 0.9896104 0.99566346 1.0 3663 tags=28%, list=24%, signal=37% CARBOXYLIC ACID TRANSMEMBRANE TRANSPORT%GOBP%GO:1905039 CARBOXYLIC ACID TRANSMEMBRANE TRANSPORT%GOBP%GO:1905039 29 -0.18831645 -0.5356048 0.99375 0.9952807 1.0 1770 tags=7%, list=12%, signal=8% ORGANIC ACID TRANSMEMBRANE TRANSPORT%GOBP%GO:1903825 ORGANIC ACID TRANSMEMBRANE TRANSPORT%GOBP%GO:1903825 29 -0.18831645 -0.5222761 0.996732 0.99627006 1.0 1770 tags=7%, list=12%, signal=8% GLYCOLYSIS%REACTOME DATABASE ID RELEASE 60%70171 GLYCOLYSIS%REACTOME DATABASE ID RELEASE 60%70171 28 -0.1870503 -0.51683515 0.996997 0.99627465 1.0 4701 tags=29%, list=31%, signal=41% NEURON DEATH%GOBP%GO:0070997 NEURON DEATH%GOBP%GO:0070997 19 -0.2069048 -0.5155547 0.98195875 0.99588186 1.0 3841 tags=26%, list=25%, signal=35% PID_SMAD2_3PATHWAY%MSIGDB_C2%PID_SMAD2_3PATHWAY PID_SMAD2_3PATHWAY%MSIGDB_C2%PID_SMAD2_3PATHWAY 17 -0.20879622 -0.50852126 0.9873737 0.9959949 1.0 843 tags=6%, list=6%, signal=6%