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{"sheet":"healthpigmentation","index":0,"n_rows":59,"n_cols":12,"rows_kept":59,"cut":false,"hidden":false,"merged":[[23,4,23,7],[22,1,22,11],[29,4,29,7],[28,1,28,11],[23,8,23,11],[23,0,24,0],[29,8,29,11],[17,0,22,0],[25,0,28,0],[47,8,47,11],[46,1,46,11],[34,1,34,11],[53,4,53,7],[58,1,58,11],[52,1,52,11],[40,1,40,11],[35,4,35,7],[35,8,35,11],[41,0,42,0],[37,0,40,0],[47,0,48,0],[53,0,54,0],[31,0,34,0],[43,0,46,0],[49,0,52,0],[55,0,58,0],[41,4,41,7],[41,8,41,11],[53,8,53,11],[47,4,47,7],[8,0,9,0],[0,0,1,0],[10,0,14,0],[14,1,14,11],[15,4,15,7],[15,8,15,11],[35,0,36,0],[29,0,30,0],[15,0,16,0],[7,1,7,11],[8,4,8,7],[8,8,8,11],[0,4,0,7],[0,8,0,11],[2,0,7,0]]}
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","Beta","p-value","Trait","N","Beta","p-value"]
["Hair Color Depth","rs12913832","HERC2","A","1 - Blond",283410.0,0.499,"<E-100","1 - Blond",19143.0,0.196286855,1.0E-96]
[null,"rs12203592","IRF4","T","2 - Red",283410.0,0.375,"<E-100","2 - Red",19143.0,0.415643622,2.84E-289]
[null,"rs17184180","SLC24A4","A","3 - Light Brown",281197.0,-0.204,"<E-100","3 - Light Brown",19143.0,-0.131003145,1.72E-56]
[{"$nulls":4},"4 - Dark Brown",null,null,null,"4 - Dark Brown"]
[{"$nulls":4},"5 - Black",null,null,null,"5 - Black"]
[null,"Reference Study: Hysi et al (2018) Nature Genetics 50, 652–656                                                                        "]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","Beta","p-value","Trait","N","Beta","p-value"]
["Hair Texture","rs17646946","TCHHL1","A","Level 1 - Straight",28964.0,"−0.21",5.82E-134,"1 - Straight",19983.0,-0.2501086,1.323493E-153]
[null,"rs74333950","WNT10A","G","Level 2 - Wavy",28964.0,0.06,9.47E-18,"2 - Wavy",19983.0,0.09005284,1.138858E-17]
[null,"rs11203346","PADI3","G","Level 3 - Curly",28964.0,"−0.07",9.24E-17,"3 - Curly",19983.0,-0.05540218,1.479428E-7]
[{"$nulls":8},"4 - Very Tight Curls"]
[null,"Reference Study: Liu et al (2018) Human Molecular Genetics 27, 559-575"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","OR","p-value","Trait","N","Beta","p-value"]
["Skin Sun Response","rs12203592","IRF4","T","Level 1 - Low Tan Response",121296.0,"1.74 ","1.05E−581","1 - Never burns",17633.0,0.219391906,2.28E-66]
[null,"rs369230","MC1R","G","Level 2 - High Tan Response",121296.0,"1.60 ","1.00E−522","2 - Burns rarely",17633.0,{"$f":"--0.09754022","v":0.09754022},4.2E-24]
[null,"rs6059655","RALY/ASIP","A",null,121296.0,"1.69 ","1.44E−315","3 - Burns moderately",17633.0,{"$f":"--0.184760205","v":0.184760205},4.26E-24]
[{"$nulls":8},"4 - Often burns"]
[{"$nulls":8},"5 - Always burns"]
[null,"Reference Study: Visconti et al (2018) Nature Communications 9, 1684"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","OR","p-value","Trait","N","OR","p-value"]
["Blue Eye Color","rs8039195","HERC2","T","Blue vs. green/brown",5130.0,13.1,"3.9E10-129","5,148 blue vs.",19982.0,{"$f":"exp(1.056977808)","v":2.87766099},3.67E-132]
[null,"rs4904868","SLC24A4","T",null,5130.0,0.67,"2.5E10-14","14,834 not-blue",19982.0,{"$f":"exp(-0.303054865)","v":0.7385585742},4.21E-32]
[null,"rs1408799","TYRP1","T",null,5130.0,0.705,"1.5E10-9",null,19982.0,{"$f":"exp(-0.23195039)","v":0.7929854623},8.49E-17]
[null,"Reference Study: Sulem et al (2008) Nature Genetics 40, 835-837"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","Beta","p-value","Trait","N","Beta","p-value"]
["Height","rs724016","ZBTB38","A","Height (m)",252972.0,-0.078,3.2E-158,"Height (in)",19581.0,{"$f":"-0.049491226","v":-0.049491226},7.14E-10]
[null,"rs143384","GDF5","A",null,247786.0,-0.075,1.2E-121,null,19581.0,-0.042279346,1.32E-7]
[null,"rs8756","HMGA2","A",null,253008.0,-0.059,4.5E-90,null,19581.0,-0.032357162,5.16E-5]
[null,"Reference Study: Wood et al (2014) Nature Genetics 46, 1173-1186"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","Beta","p-value","Trait","N","Beta","p-value"]
["BMI","rs1558902","FTO","A","BMI (kg/m²)",336974.0,0.081,1.13E-156,"BMI (kg/m²)",19278.0,0.081249169,2.62E-14]
[null,"rs6567160","MC4R","C",null,339006.0,0.056,6.68E-59,null,19278.0,0.05947487,1.09E-6]
[null,"rs13021737","TMEM18","G",null,333169.0,0.06,5.44E-54,null,19278.0,0.068498727,6.39E-7]
[null,"Reference Study: Locke et al (2015) Nature 518, 197-206"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","OR","p-value","Trait","N","OR","p-value"]
["Type 1 Diabetes","rs9273364","HLA-DQB1","G","2,660 cases",391416.0,{"$f":"exp(0.814)","v":2.256917626},"2.78E-142","106 cases",17529.0,{"$f":"exp(1.328054715)","v":3.77369533},1.27E-14]
[null,"rs2596560","MICA","C","288,756 controls",391416.0,{"$f":"exp(0.486)","v":1.625799996},1.13E-46,"17,424 controls",17529.0,{"$f":"exp(0.787476858)","v":2.197843952},4.38E-6]
[null,"rs689","INS-IGF2","T",null,391416.0,{"$f":"exp(0.284)","v":1.328432931},8.05E-20,null,17529.0,{"$f":"exp(0.237533933)","v":1.268118027},0.124019585]
[null,"Reference Study: Bycroft et al (2017) bioRxiv, 166298"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","OR","p-value","Trait","N","OR","p-value"]
["Type 2 Diabetes","rs7903146","TCF7L2","T","48,286 cases",298957.0,{"$f":"exp(0.2367)","v":1.267060942},1.36E-212,"848 cases",17529.0,{"$f":"exp(0.261781368)","v":1.299242455},8.44E-6]
[null,"rs1558902","FTO","A","250,671 controls",298957.0,{"$f":"exp(0.1167)","v":1.123782244},1.63E-50,"16,898 controls",17529.0,{"$f":"exp(0.217049953)","v":1.242406163},8.82E-5]
[null,"rs7756992","CDKAL1","A",null,298957.0,{"$f":"exp(-0.104)","v":0.9012252974},1.22E-41,null,17529.0,{"$f":"exp(-0.299211718)","v":0.7414024246},5.71E-7]
[null,"Reference Study: DIAGRAM Consortium T2D GWAS meta-analysis - European Summary Statistics (published in Mahajan et al (2018) Nature Genetics 50, 559-571)"]
[{"$nulls":4},"Reference",null,null,null,"GFG"]
[null,"Published Locus","Nearest Gene","EA","Trait","N","OR","p-value","Trait","N","OR","p-value"]
["Asthma","rs2952156","ERBB2, PGAP3, MIEN1","G","19,954 cases",{"$f":"19954+107715","v":127669},"0.86",7.6E-29,"4,378 cases",16093.0,0.926019387,0.005249528]
[null,"rs9272346","HLA-DRB1, HLA-DQA1","A","107,715 controls",127669,"1.16",4.8E-28,"11,715 controls",16093.0,1.094909793,5.5653E-4]
[null,"rs10455025","SLC25A46, TSLP","C",null,127669,"1.15",2.0E-25,null,16093.0,1.057548362,0.044953264]
[null,"Reference Study: Demenais et al (2018) Nature Genetics 50, 42-53"]