This PDF file includes:

• Scheme S1. Synthesis route of polymers.
• Fig. S1. Characterization of the complex.
• Fig. S2. ¹H NMR spectra of various compounds synthesized.
• Fig. S3. In vitro insulin release studies.
• Fig. S4. Evaluation of insulin complexes in type 1 diabetic mice.
• Fig. S5. Host response and toxicity evaluation in diabetic mice.
• Fig. S6. The Masson’s trichrome staining sections of the skin with or without treatment.
• Fig. S7. The immunofluorescence staining sections of the skin with or without treatment.
• Fig. S8 Characterization of MN array patch.
• Fig. S9. Glucose challenge study in diabetic minipigs.
• Table S1. The BGLs of diabetic pigs.

Download PDF