The PDF file includes:

• Fig. S1. Conservation of the WOM expression signatures across mammals.
• Fig. S2. OR gene expression in mammals.
• Fig. S3. Abundance and ligand biases for highly conserved canonical/OR-expressing OSN subtypes across mammalian evolution.
• Fig. S4. The muscone human OR, OR5AN1, is also weakly activated by the KFO β-ionone.
• Fig. S5. Distribution of mouse and human OR genes that detect exclusively other odorants.
• Legends for data files S1 to S5

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Other Supplementary Material for this manuscript includes the following:

• Data file S1 (Microsoft Excel format). Sample information, accession numbers, RNA-seq quality metrics, and gene expression estimates.
• Data file S2 (Microsoft Excel format). Differential expression analysis for all pairwise comparisons between the 9785 dog, mouse, rat, marmoset, macaque, and human.
• Data file S3 (Microsoft Excel format). Expression estimates for the OR repertoires of dog, mouse, rat, marmoset, macaque, and human.
• Data file S4 (Microsoft Excel format). Composition of the highly conserved 73 OGGs across mammals.
• Data file S5 (Microsoft Excel format). Expression estimates of the most and least abundant ORs or OSN subtypes.