geneSet Enrichment Score Normalized Enrichment Score pValue signed logp FDR link geneSet size leadingEdgeNumber leading Edge KEGG_GALACTOSE_METABOLISM 0.630116967 1.617031501 0.004347826 2.361727837 0.049288883 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GALACTOSE_METABOLISM 26 11 AKR1B1;B4GALT2;GALK1;GALT;HK3;LCT;PFKL;PFKP;PGM1;PGM2;UGP2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN 0.66550247 1.699062039 0.004282655 2.368286886 0.024198303 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN 26 14 NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;SEH1L KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0.606870856 1.626932966 0.006864989 2.163360183 0.04647086 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 34 11 ADI1;AMD1;CBS;DNMT1;DNMT3A;DNMT3B;IL4I1;LDHB;MTAP;SRM;TRDMT1 PID_MYC_ACTIV_PATHWAY 0.625221555 1.951948486 0 16 4.78E-04 http://www.broadinstitute.org/gsea/msigdb/cards/PID_MYC_ACTIV_PATHWAY 78 41 ACTL6A;BAX;BCAT1;BIRC5;CAD;CCNB1;CDC25A;CDCA7;CDK4;DDX18;E2F3;EIF4A1;EIF4G1;ENO1;FOSL1;GAPDH;HMGA1;HSPD1;KIR3DL1;LDHA;LIN28B;MMP9;MTDH;MYC;NCL;NME1;ODC1;PDCD10;PIM1;POLR3D;PTMA;RCC1;RUVBL1;SLC2A1;SNAI1;SUPT7L;TAF4B;TERT;TFRC;TK1;TRRAP KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM 0.717379767 1.672822853 0.004246284 2.371990912 0.031037505 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM 16 5 HAO1;MDH1;MDH2;MTHFD1L;MTHFD2 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES 0.774876041 1.911290591 0 16 0.001202 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES 25 10 B3GNT3;B3GNT4;B3GNT5;B4GALT2;FUT3;FUT4;FUT5;GCNT2;ST3GAL6;ST8SIA1 REACTOME_TRNA_AMINOACYLATION 0.606935209 1.72058758 0 16 0.019122852 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRNA_AMINOACYLATION 42 27 AARS;AARS2;AIMP2;CARS;CARS2;DARS;DARS2;EEF1E1;EPRS;FARSA;FARSB;GARS;IARS;KARS;MARS;MARS2;NARS;NARS2;PARS2;PPA1;RARS2;SARS2;TARS;VARS;WARS;YARS;YARS2 REACTOME_HIV_INFECTION 0.51777253 1.799038923 0 16 0.006799887 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_INFECTION 185 93 AP1B1;AP1M1;AP1S1;AP2M1;ARF1;BANF1;CD247;CD8B;CXCR4;ERCC3;FEN1;FYN;GTF2E2;GTF2F2;GTF2H4;HCK;HLA-A;HMGA1;LCK;NCBP1;NMT2;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;POM121;PPIA;PSIP1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RAE1;RAN;RANBP1;RANGAP1;RBX1;RCC1;RNGTT;RNMT;RPS27A;SEH1L;SLC25A5;SSRP1;SUPT5H;TAF11;TAF13;TAF4B;TAF5;TAF6;TBP;UBA52;VPS37B;XPO1;XRCC6 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0.573271997 1.902207346 0 16 0.001393948 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 117 66 AP1B1;AP1M1;AP1S1;AP2M1;ARF1;BANF1;CD247;CD8B;FYN;HCK;HLA-A;HMGA1;LCK;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;PPIA;PSIP1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RAE1;RAN;RANBP1;RANGAP1;RBX1;RCC1;RPS27A;SEH1L;SLC25A5;UBA52;XPO1 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0.727433027 1.787315179 0 16 0.00805367 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 24 16 AARS;AIMP2;CARS;DARS;EEF1E1;EPRS;FARSB;GARS;IARS;KARS;MARS;PPA1;TARS;VARS;WARS;YARS REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0.585638755 1.954196957 0 16 4.92E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 122 68 CLP1;CPSF1;CPSF3;CSTF3;DHX38;DHX9;EFTUD2;GTF2F2;HNRNPA2B1;HNRNPA3;HNRNPD;HNRNPL;HNRNPR;HNRNPUL1;LSM2;MAGOH;NCBP1;NUDT21;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;PABPN1;PCBP1;PHF5A;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2K;POM121;PTBP1;RAE1;RBM8A;RNPS1;SEH1L;SF3A3;SF3B2;SF3B3;SF3B4;SF3B5;SLBP;SMC1A;SNRNP40;SNRPA;SNRPA1;SNRPB;SNRPB2;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;TXNL4A;U2AF1;UPF3B;YBX1 REACTOME_RNA_POL_II_TRANSCRIPTION 0.521060153 1.661390426 0 16 0.034986703 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_TRANSCRIPTION 85 43 CLP1;CPSF1;CPSF3;CSTF3;DHX38;ERCC3;GTF2E2;GTF2F2;GTF2H4;LSM10;MAGOH;NCBP1;NUDT21;PABPN1;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;RBM8A;RNGTT;RNMT;RNPS1;SLBP;SNRPB;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;SSRP1;SUPT5H;TAF11;TAF13;TAF4B;TAF5;TAF6;TBP;U2AF1;UPF3B;ZNF473 REACTOME_MRNA_PROCESSING 0.555540411 1.894272376 0 16 0.001570154 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_PROCESSING 142 80 ADARB1;CLP1;CPSF1;CPSF3;CPSF7;CSTF3;DHX38;DHX9;EFTUD2;ERCC3;GTF2F2;GTF2H4;HNRNPA2B1;HNRNPA3;HNRNPD;HNRNPH1;HNRNPL;HNRNPR;HNRNPUL1;LSM10;LSM2;MAGOH;NCBP1;NUDT21;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;PABPN1;PCBP1;PHF5A;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;POM121;PTBP1;RAE1;RBM8A;RBMX;RNGTT;RNMT;RNPS1;SEH1L;SF3A3;SF3B2;SF3B3;SF3B4;SF3B5;SLBP;SMC1A;SNRNP40;SNRPA;SNRPA1;SNRPB;SNRPB2;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;SUPT5H;TXNL4A;U2AF1;UPF3B;YBX1;ZNF473 REACTOME_MRNA_SPLICING 0.568655501 1.843129488 0 16 0.003440027 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING 94 56 CLP1;CPSF1;CPSF3;CPSF7;CSTF3;DHX38;DHX9;EFTUD2;GTF2F2;HNRNPA2B1;HNRNPA3;HNRNPD;HNRNPH1;HNRNPL;HNRNPR;HNRNPUL1;LSM2;MAGOH;NCBP1;NUDT21;PABPN1;PCBP1;PHF5A;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;PTBP1;RBM8A;RBMX;RNPS1;SF3A3;SF3B2;SF3B3;SF3B4;SF3B5;SMC1A;SNRNP40;SNRPA;SNRPA1;SNRPB;SNRPB2;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;TXNL4A;U2AF1;UPF3B;YBX1 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0.611012271 1.674412622 0.004474273 2.349277528 0.030837602 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING_MINOR_PATHWAY 36 24 EFTUD2;GTF2F2;LSM2;NCBP1;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;SF3B2;SF3B3;SF3B4;SF3B5;SNRNP40;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;TXNL4A REACTOME_TRANSCRIPTION 0.466963961 1.617723463 0 16 0.049208313 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTION 181 75 CBX3;CLP1;CPSF1;CPSF3;CSTF3;DHX38;EHMT2;ERCC3;GTF2E2;GTF2F2;GTF2H4;GTF3C2;GTF3C5;H2AFX;H2AFZ;HIST1H2AB;HIST1H2BJ;HIST1H2BL;HIST1H2BO;HIST1H3A;HIST1H3B;HIST1H3F;HIST1H3I;HIST1H3J;HIST1H4B;HIST1H4C;HIST1H4E;LSM10;MAGOH;MBD2;NCBP1;NFIB;NUDT21;PABPN1;POLR1A;POLR1B;POLR1C;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;POLR3C;POLR3D;POLR3F;RBM8A;RNGTT;RNMT;RNPS1;SLBP;SNAPC1;SNRPB;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;SSB;SSRP1;SUPT5H;TAF11;TAF13;TAF1A;TAF1C;TAF4B;TAF5;TAF6;TBP;TFAM;TFB2M;U2AF1;UPF3B;ZNF473 REACTOME_DNA_REPAIR 0.505661133 1.657668388 0.0025 2.602059992 0.035919425 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPAIR 102 34 BRCA2;BRIP1;FANCA;FANCB;FANCC;FANCD2;FANCE;FANCG;FANCL;FEN1;GTF2H4;H2AFX;MAD2L2;MDC1;MUTYH;PCNA;POLD1;POLD3;POLE2;POLR2C;POLR2D;POLR2F;POLR2K;PRKDC;RAD51;RFC2;RFC3;RFC4;RPA1;RPS27A;TDG;UBE2T;USP1;XRCC6 REACTOME_INFLUENZA_LIFE_CYCLE 0.55448336 1.857996674 0 16 0.002956205 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLUENZA_LIFE_CYCLE 135 56 CALR;CLTA;GTF2F2;HSP90AA1;IPO5;NUP107;NUP153;NUP155;NUP205;NUP35;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POLR2B;POLR2C;POLR2D;POLR2F;POLR2H;POLR2I;POLR2K;POM121;RAE1;RAN;RPL13;RPL18A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL5;RPL7;RPL8;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS7;RPS8;RPSA;SEH1L;TPR;UBA52;XPO1 REACTOME_HIV_LIFE_CYCLE 0.537501115 1.7542353 0 16 0.012709522 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_LIFE_CYCLE 106 41 BANF1;CXCR4;FEN1;GTF2E2;GTF2F2;GTF2H4;HMGA1;NMT2;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP62;NUP85;NUP88;NUP93;NUPL2;POLR2C;POLR2D;POLR2F;POLR2K;POM121;PPIA;PSIP1;RAN;RANBP1;RANGAP1;RCC1;RNGTT;RPS27A;SEH1L;SSRP1;SUPT5H;TAF11;TAF4B;TAF5;VPS37B;XPO1;XRCC6 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0.510223706 1.62912815 0 16 0.046760402 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 93 32 GTF2E2;GTF2H4;NMT2;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP62;NUP85;NUP88;NUP93;NUPL2;POLR2C;POLR2D;POLR2F;POLR2K;RAN;RANBP1;RANGAP1;RCC1;RNGTT;RPS27A;SEH1L;SSRP1;SUPT5H;TAF11;TAF4B;TAF5;VPS37B;XPO1 REACTOME_METABOLISM_OF_NUCLEOTIDES 0.529944147 1.658434762 0 16 0.035946 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NUCLEOTIDES 70 28 ADA;ADSL;AK2;AMPD2;APRT;CAD;CMPK1;DGUOK;DHODH;DPYS;DTYMK;GART;GMPS;HPRT1;IMPDH1;NME1;NT5C2;PAICS;PNP;PPAT;RRM2;TK1;TXN;TXNRD1;TYMS;UCK2;UMPS;UPP1 KEGG_DNA_REPLICATION 0.766884985 2.096162637 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_DNA_REPLICATION 36 22 DNA2;FEN1;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;PCNA;POLA2;POLD1;POLD3;POLE2;PRIM2;RFC2;RFC3;RFC4;RNASEH1;RNASEH2A;RPA1;RPA4;SSBP1 KEGG_HOMOLOGOUS_RECOMBINATION 0.6483369 1.622889857 0.011441648 1.941511434 0.048583172 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_HOMOLOGOUS_RECOMBINATION 24 13 BLM;BRCA2;EME1;POLD1;POLD3;RAD51;RAD54B;RAD54L;RPA1;RPA4;SSBP1;TOP3B;XRCC2 REACTOME_CELL_CYCLE 0.635798585 2.360546819 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE 376 155 AHCTF1;AURKA;AURKB;BIRC5;BUB1;BUB1B;CCNA1;CCNA2;CCNB1;CCNB2;CCNE1;CCNE2;CDC20;CDC25A;CDC25B;CDC25C;CDC45;CDC6;CDC7;CDCA8;CDK1;CDK2;CDK4;CDK6;CDKN2A;CDKN2C;CDKN2D;CDT1;CENPA;CENPH;CENPI;CENPJ;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;CENPT;CEP57;CEP72;CEP76;CHEK1;CHEK2;CKAP5;CKS1B;CUL1;DBF4;DKC1;DNA2;DSN1;E2F1;E2F2;E2F3;E2F4;E2F5;ERCC6L;FBXO5;FEN1;GINS1;GINS2;GINS4;GMNN;H2AFX;H2AFZ;HIST1H2BJ;HIST1H4C;HJURP;INCENP;KIF18A;KIF20A;KIF23;KIF2C;KNTC1;LIN9;LMNB1;MAD2L1;MAPRE1;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;MYBL2;MYC;NDC80;NEK2;NUF2;NUP107;NUP37;NUP85;OIP5;PCNA;PCNT;PKMYT1;PLK1;PLK4;POLA2;POLD1;POLD3;POLE2;PPP2R5D;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD7;PSME4;PTTG1;RAD21;RANGAP1;RBL1;RCC2;RFC2;RFC3;RFC4;RPA1;RPA4;RPS27A;RRM2;RUVBL1;SEC13;SEH1L;SKA1;SKP2;SMC1B;SPC24;SPC25;STAG3;SUN2;TERT;TFDP1;TUBA4A;TUBB;TYMS;UBE2C;UBE2D1;XPO1;YWHAG;ZW10;ZWILCH;ZWINT REACTOME_CELL_CYCLE_MITOTIC 0.667380195 2.435709208 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_MITOTIC 290 140 AHCTF1;AURKA;AURKB;BIRC5;BUB1;BUB1B;CCNA1;CCNA2;CCNB1;CCNB2;CCNE1;CCNE2;CDC20;CDC25A;CDC25B;CDC25C;CDC45;CDC6;CDC7;CDCA8;CDK1;CDK2;CDK4;CDK6;CDKN2A;CDKN2C;CDKN2D;CDT1;CENPA;CENPH;CENPI;CENPJ;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;CENPT;CEP57;CEP72;CEP76;CKAP5;CKS1B;CUL1;DBF4;DNA2;DSN1;E2F1;E2F2;E2F3;E2F4;E2F5;ERCC6L;FBXO5;FEN1;GINS1;GINS2;GINS4;GMNN;INCENP;KIF18A;KIF20A;KIF23;KIF2C;KNTC1;LIN9;MAD2L1;MAPRE1;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;MYBL2;MYC;NDC80;NEK2;NUF2;NUP107;NUP37;NUP85;PCNA;PCNT;PKMYT1;PLK1;PLK4;POLA2;POLD1;POLD3;POLE2;PPP2R5D;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD7;PSME4;PTTG1;RAD21;RANGAP1;RBL1;RCC2;RFC2;RFC3;RFC4;RPA1;RPA4;RPS27A;RRM2;SEC13;SEH1L;SKA1;SKP2;SPC24;SPC25;TFDP1;TUBA4A;TUBB;TYMS;UBE2C;UBE2D1;XPO1;YWHAG;ZW10;ZWILCH;ZWINT REACTOME_SYNTHESIS_OF_DNA 0.694559746 2.179061861 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_DNA 84 56 CCNA1;CCNA2;CDC45;CDC6;CDK2;CDT1;DNA2;FEN1;GINS1;GINS2;GINS4;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;PCNA;POLA2;POLD1;POLD2;POLD3;POLE;POLE2;PRIM2;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;RFC2;RFC3;RFC4;RFC5;RPA1;RPS27A;UBA52 REACTOME_CHROMOSOME_MAINTENANCE 0.57943044 1.888980377 0 16 0.001681773 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHROMOSOME_MAINTENANCE 112 40 ACD;CENPA;CENPH;CENPI;CENPK;CENPN;CENPO;CENPQ;DKC1;DNA2;FEN1;H2AFX;H2AFZ;HIST1H2BJ;HIST1H4B;HIST1H4C;HJURP;LMNA;LMNB1;OIP5;PCNA;POLA2;POLD1;POLD2;POLD3;POLE2;PRIM2;RAD21;RFC2;RFC3;RFC4;RFC5;RPA1;RUVBL1;SMC1A;SMC1B;STAG3;SUN2;TERF2;TERT REACTOME_LAGGING_STRAND_SYNTHESIS 0.710622343 1.703727825 0.016203704 1.790385708 0.023142922 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LAGGING_STRAND_SYNTHESIS 19 11 DNA2;FEN1;PCNA;POLA2;POLD1;POLD3;PRIM2;RFC2;RFC3;RFC4;RPA1 REACTOME_DNA_REPLICATION 0.734114285 2.519249506 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPLICATION 175 100 AHCTF1;AURKB;BIRC5;BUB1;BUB1B;CCNA1;CCNA2;CDC20;CDC45;CDC6;CDC7;CDCA8;CDK2;CDT1;CENPA;CENPH;CENPI;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;CENPT;CKAP5;DBF4;DNA2;DSN1;E2F1;E2F2;E2F3;ERCC6L;FBXO5;FEN1;GINS1;GINS2;GINS4;GMNN;INCENP;KIF18A;KIF20A;KIF23;KIF2C;KNTC1;MAD2L1;MAPRE1;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;NDC80;NUF2;NUP107;NUP37;NUP85;PCNA;PLK1;POLA2;POLD1;POLD3;POLE2;PPP2R5D;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD7;PSME4;RAD21;RANGAP1;RCC2;RFC2;RFC3;RFC4;RPA1;RPA4;RPS27A;SEC13;SEH1L;SKA1;SPC24;SPC25;XPO1;ZW10;ZWILCH;ZWINT REACTOME_TELOMERE_MAINTENANCE 0.529613445 1.631669173 0 16 0.045731915 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TELOMERE_MAINTENANCE 73 36 ACD;DKC1;DNA2;FEN1;H2AFX;H2AFZ;HIST1H2AB;HIST1H2BJ;HIST1H2BK;HIST1H2BL;HIST1H2BM;HIST1H2BO;HIST1H4A;HIST1H4B;HIST1H4C;HIST1H4E;LIG1;PCNA;POLA2;POLD1;POLD2;POLD3;POLE;POLE2;PRIM1;PRIM2;RFC2;RFC3;RFC4;RFC5;RPA1;RPA2;RUVBL1;TERF2;TERT;WRAP53 REACTOME_EXTENSION_OF_TELOMERES 0.721291453 1.864152727 0 16 0.002824338 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTENSION_OF_TELOMERES 27 15 DKC1;DNA2;FEN1;PCNA;POLA2;POLD1;POLD3;POLE2;PRIM2;RFC2;RFC3;RFC4;RPA1;RUVBL1;TERT REACTOME_S_PHASE 0.646503379 2.075792299 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_S_PHASE 100 60 CCNA1;CCNA2;CCNE1;CCNE2;CDC25A;CDC25B;CDC45;CDC6;CDK2;CDK4;CDT1;CKS1B;CUL1;DNA2;FEN1;GINS1;GINS2;GINS4;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;MYC;PCNA;POLA2;POLD1;POLD2;POLD3;POLE2;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;RFC2;RFC3;RFC4;RPA1;RPS27A;SKP2 REACTOME_DNA_STRAND_ELONGATION 0.794944448 2.080037322 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_STRAND_ELONGATION 30 22 CDC45;DNA2;FEN1;GINS1;GINS2;GINS4;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;PCNA;POLA2;POLD1;POLD3;PRIM2;RFC2;RFC3;RFC4;RPA1 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX 0.856313271 2.124711241 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX 24 19 CDC45;CDC6;CDC7;CDK2;CDT1;DBF4;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;POLA2;POLE2;PRIM2;RPA1;RPA4 REACTOME_M_G1_TRANSITION 0.735412367 2.232228692 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_M_G1_TRANSITION 72 45 CDC45;CDC6;CDC7;CDK2;CDT1;DBF4;E2F1;E2F2;E2F3;GMNN;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;POLA2;POLE2;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;RPA1;RPA4;RPS27A REACTOME_G1_S_TRANSITION 0.654167626 2.082546416 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_TRANSITION 100 52 CCNA1;CCNA2;CCNB1;CCNE1;CCNE2;CDC25A;CDC45;CDC6;CDC7;CDK1;CDK2;CDT1;CKS1B;CUL1;DBF4;E2F1;FBXO5;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;MYC;PCNA;PKMYT1;POLA2;POLE2;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD7;RPA1;RPA4;RPS27A;RRM2;SKP2;TFDP1;TYMS REACTOME_MITOTIC_G1_G1_S_PHASES 0.665881475 2.191826928 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G1_G1_S_PHASES 124 59 CCNA2;CCNB1;CCNE1;CCNE2;CDC25A;CDC45;CDC6;CDC7;CDK1;CDK2;CDK4;CDK6;CDKN2A;CDKN2C;CDKN2D;CDT1;CKS1B;CUL1;DBF4;E2F1;E2F2;E2F3;E2F4;E2F5;FBXO5;LIN9;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;MYBL2;MYC;PCNA;PKMYT1;POLA2;POLE2;PRIM2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMD12;PSMD14;PSMD2;PSMD7;RBL1;RPA1;RPA4;RPS27A;RRM2;SKP2;TFDP1;TYMS REACTOME_MITOTIC_M_M_G1_PHASES 0.743197522 2.500269538 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_M_M_G1_PHASES 155 87 AHCTF1;AURKB;BIRC5;BUB1;BUB1B;CDC20;CDC45;CDC6;CDC7;CDCA8;CDK2;CDT1;CENPA;CENPH;CENPI;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;CENPT;CKAP5;DBF4;DSN1;E2F1;E2F2;E2F3;ERCC6L;FBXO5;GMNN;INCENP;KIF18A;KIF20A;KIF23;KIF2C;KNTC1;MAD2L1;MAPRE1;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;NDC80;NUF2;NUP107;NUP37;NUP85;PLK1;POLA2;POLE2;PPP2R5D;PRIM2;PSMA2;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD7;PSME4;RAD21;RANGAP1;RCC2;RPA1;RPA4;RPS27A;SEC13;SEH1L;SKA1;SPC24;SPC25;XPO1;ZW10;ZWILCH;ZWINT REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION 0.769628542 1.935660582 0 16 7.12E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION 27 16 CCNB1;CCNE1;CDC25A;CDC45;CDC6;CDK1;CDT1;E2F1;FBXO5;MCM8;PCNA;POLA2;PRIM2;RRM2;TFDP1;TYMS KEGG_ONE_CARBON_POOL_BY_FOLATE 0.753248309 1.725860244 0.006696429 2.17415676 0.017960288 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ONE_CARBON_POOL_BY_FOLATE 17 6 FTCD;GART;MTHFD1L;MTHFD2;SHMT2;TYMS PID_E2F_PATHWAY 0.673997867 2.050520604 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/PID_E2F_PATHWAY 70 26 CCNA2;CCNE1;CCNE2;CDC25A;CDC6;CDK1;CDKN2A;CDKN2C;E2F1;E2F2;E2F3;E2F4;E2F5;E2F7;MCM3;MYBL2;MYC;RANBP1;RBL1;RRM2;TFDP1;TFDP2;TK1;TOPBP1;TYMS;WASF1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 0.876298088 1.982124902 0 16 2.97E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 16 12 CCNE1;CDC25A;CDC45;CDC6;CDK1;CDT1;E2F1;FBXO5;PCNA;RRM2;TFDP1;TYMS KEGG_PRIMARY_IMMUNODEFICIENCY 0.639051073 1.730340227 0.004175365 2.379305519 0.017114356 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PRIMARY_IMMUNODEFICIENCY 35 27 ADA;AICDA;CD19;CD3D;CD3E;CD4;CD40;CD40LG;CD79A;CD8A;CD8B;CIITA;DCLRE1C;ICOS;IL2RG;IL7R;JAK3;LCK;PTPRC;RFX5;RFXANK;RFXAP;TAP1;TAP2;TNFRSF13C;UNG;ZAP70 REACTOME_PERK_REGULATED_GENE_EXPRESSION 0.65014685 1.681551621 0.004494382 2.347330016 0.028301747 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PERK_REGULATED_GENE_EXPRESSION 26 14 ASNS;ATF4;CCL2;DDIT3;EXOSC2;EXOSC3;EXOSC4;EXOSC5;EXOSC6;EXOSC8;EXOSC9;HSPA5;KHSRP;NFYA REACTOME_ACTIVATION_OF_GENES_BY_ATF4 0.662776505 1.65452298 0.009174312 2.037426499 0.036582338 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_GENES_BY_ATF4 23 13 ASNS;ATF4;CCL2;DDIT3;EXOSC2;EXOSC3;EXOSC4;EXOSC5;EXOSC6;EXOSC8;EXOSC9;KHSRP;NFYA PID_RB_1PATHWAY 0.53361632 1.627021593 0.002293578 2.63948649 0.046856921 http://www.broadinstitute.org/gsea/msigdb/cards/PID_RB_1PATHWAY 65 20 CCNA2;CCNE1;CDK2;CDK4;CDK6;CDKN2A;CEBPB;CKM;CSF2;DNMT1;E2F1;E2F2;E2F3;E2F4;MET;SKP2;SMARCA4;SMARCB1;SUV39H1;TFDP1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC 0.649533849 1.859579943 0 16 0.002996614 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC 48 30 ODC1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4 BIOCARTA_DC_PATHWAY 0.665794545 1.647817568 0.004464286 2.350248019 0.038806764 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_DC_PATHWAY 22 13 CD2;CD40;CD5;CD7;CSF2;IFNB1;IFNG;IL10;IL12A;IL12B;IL13;TLR2;TLR9 BIOCARTA_PROTEASOME_PATHWAY 0.676714164 1.730939188 0 16 0.017143429 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_PROTEASOME_PATHWAY 28 22 PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD8;RPN1;RPN2;UBE2A REACTOME_TRANSLATION 0.493083405 1.6554426 0 16 0.036531991 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSLATION 145 53 DDOST;EEF1B2;EEF1G;EIF2B3;EIF2S2;EIF3B;EIF3C;EIF3D;EIF3E;EIF3K;EIF4A1;EIF4EBP1;EIF4G1;EIF4H;EIF5B;PABPC1;RPL13;RPL18A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL5;RPL7;RPL8;RPN1;RPN2;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS7;RPS8;RPSA;SEC61A1;SEC61A2;SEC61B;SEC61G;SRP68;SRPRB;SSR1;SSR2;SSR4;TRAM1;UBA52 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0.527348319 1.622851078 0.002242152 2.64933486 0.048188956 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 64 32 EIF2AK2;EIF4A1;EIF4A3;EIF4G1;HERC5;KPNA2;KPNA3;KPNA4;MX1;MX2;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;PLCG1;POM121;RAE1;RPS27A;SEH1L;STAT1;TRIM25;UBA52;UBE2E1;USP18 REACTOME_MITOTIC_G2_G2_M_PHASES 0.548656086 1.69158971 0 16 0.025528082 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G2_G2_M_PHASES 73 26 CCNA1;CCNA2;CCNB1;CCNB2;CDC25A;CDC25B;CDC25C;CDK1;CDK2;CENPJ;CEP57;CEP72;CEP76;CKAP5;E2F1;E2F3;MAPRE1;NEK2;PCNT;PKMYT1;PLK1;PLK4;TUBA4A;TUBB;XPO1;YWHAG REACTOME_MITOTIC_PROMETAPHASE 0.755164236 2.36862684 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_PROMETAPHASE 79 44 AHCTF1;AURKB;BIRC5;BUB1;BUB1B;CDC20;CDCA8;CENPA;CENPH;CENPI;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;CENPT;CKAP5;DSN1;ERCC6L;INCENP;KIF18A;KIF2C;KNTC1;MAD2L1;MAPRE1;NDC80;NUF2;NUP107;NUP85;PLK1;PPP2R5D;RAD21;RANGAP1;RCC2;SEC13;SEH1L;SKA1;SPC24;SPC25;XPO1;ZW10;ZWILCH;ZWINT REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION 0.611439754 1.872250528 0 16 0.002435308 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION 72 45 CALR;CTSS;CYBA;HLA-A;HLA-B;HLA-F;HLA-G;NCF2;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;SEC61A1;SEC61A2;SEC61B;SEC61G;TAP1;TAP2;UBA52 REACTOME_ER_PHAGOSOME_PATHWAY 0.69191957 2.053804992 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ER_PHAGOSOME_PATHWAY 58 42 CALR;HLA-A;HLA-B;HLA-F;HLA-G;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;SEC61A1;SEC61A2;SEC61B;SEC61G;TAP1;TAP2;UBA52 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0.514362553 1.665886398 0 16 0.033656006 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 106 45 EIF2S2;EIF3B;EIF3C;EIF3D;EIF3E;EIF3H;EIF3I;EIF3K;EIF4A1;EIF4G1;EIF4H;PABPC1;RPL13;RPL18A;RPL21;RPL24;RPL27A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL4;RPL5;RPL7;RPL8;RPLP2;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS24;RPS25;RPS27A;RPS3;RPS6;RPS7;RPS8;RPSA;UBA52 REACTOME_METABOLISM_OF_MRNA 0.520912417 1.812632316 0 16 0.005498617 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_MRNA 207 89 CNOT3;DCPS;EDC4;EIF4A1;EIF4A3;EIF4G1;ELAVL1;EXOSC2;EXOSC3;EXOSC4;EXOSC5;EXOSC6;EXOSC8;EXOSC9;HNRNPD;KHSRP;LSM2;LSM4;LSM5;LSM6;MAGOH;MAPK14;NCBP1;PABPC1;PATL1;PRKCA;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB8;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RBM8A;RNPS1;RPL13;RPL18A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL5;RPL7;RPL8;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS7;RPS8;RPSA;SMG5;SMG7;UBA52;UPF2;UPF3B;XPO1;YWHAZ REACTOME_METABOLISM_OF_RNA 0.55336543 1.973456192 0 16 3.17E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_RNA 250 108 CLNS1A;CNOT3;DCPS;EDC4;EIF4A1;EIF4A3;EIF4G1;ELAVL1;EXOSC2;EXOSC3;EXOSC4;EXOSC5;EXOSC6;EXOSC8;EXOSC9;GEMIN4;GEMIN6;HNRNPD;KHSRP;LSM2;LSM4;LSM6;MAGOH;MAPK14;NCBP1;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;PABPC1;PATL1;POM121;PRKCA;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RAE1;RBM8A;RNPS1;RPL13;RPL18A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL5;RPL7;RPL8;RPS10;RPS12;RPS16;RPS18;RPS19;RPS20;RPS21;RPS27A;RPS7;RPSA;SEH1L;SMG5;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;TGS1;UBA52;UPF2;UPF3B;WDR77;XPO1;YWHAZ REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0.50711989 1.633143318 0 16 0.045361596 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 105 39 EIF4A3;EIF4G1;MAGOH;NCBP1;NCBP2;PABPC1;RBM8A;RNPS1;RPL13;RPL18A;RPL30;RPL35A;RPL36A;RPL37;RPL38;RPL39;RPL5;RPL7;RPL8;RPLP2;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS3;RPS7;RPS8;RPSA;SMG5;SMG7;UBA52;UPF2;UPF3B REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 0.599255244 1.731275218 0.002331002 2.632457293 0.01728085 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 49 20 EIF2S2;EIF3B;EIF3C;EIF3D;EIF3E;EIF3K;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS3;RPS7;RPS8;RPSA REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 0.574324106 1.696997827 0.002272727 2.643452677 0.024626407 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 57 25 EIF2S2;EIF3B;EIF3C;EIF3D;EIF3E;EIF3K;EIF4A1;EIF4EBP1;EIF4G1;EIF4H;PABPC1;RPS10;RPS12;RPS16;RPS17;RPS18;RPS19;RPS20;RPS21;RPS25;RPS27A;RPS3;RPS7;RPS8;RPSA REACTOME_ORC1_REMOVAL_FROM_CHROMATIN 0.689586282 2.012634989 0 16 1.54E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ORC1_REMOVAL_FROM_CHROMATIN 59 37 CCNA1;CCNA2;CDC6;CDK2;CDT1;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;RPS27A;UBA52 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX 0.896669498 1.683973391 0 16 0.027784007 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX 8 7 CDC6;CDT1;E2F1;E2F2;E2F3;GMNN;RPS27A REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT 0.699909799 1.976163154 0 16 3.28E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT 48 34 CDC25A;CHEK1;CHEK2;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 0.692188218 1.938595241 0 16 6.65E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 46 33 CDC6;CDK2;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_REGULATION_OF_APOPTOSIS 0.607240904 1.774458133 0 16 0.00982323 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_APOPTOSIS 56 36 ARHGAP10;CASP3;DAPK1;DCC;MAGED1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_CELL_CYCLE_CHECKPOINTS 0.680281218 2.175900218 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_CHECKPOINTS 104 43 BUB1B;CCNB1;CCNB2;CCNE1;CCNE2;CDC20;CDC25A;CDC25C;CDC45;CDC6;CDC7;CDK1;CDK2;CHEK1;CHEK2;DBF4;MAD2L1;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;PSMA4;PSMA5;PSMA7;PSMB2;PSMB4;PSMC2;PSMD12;PSMD14;PSMD2;PSMD7;PSME4;RFC2;RFC3;RFC4;RPA1;RPS27A;UBE2C;UBE2D1 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ 0.570032164 1.692732741 0 16 0.025910124 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ 62 35 CCNA1;CCNA2;CCNE1;CCNE2;CDC25A;CDK2;CKS1B;CUL1;MYC;PKMYT1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;RPS27A;SKP2;UBA52 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE 0.650643255 1.85949087 0 16 0.002943104 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE 52 34 CCNE1;CCNE2;CDK2;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_FANCONI_ANEMIA_PATHWAY 0.802073807 1.916170522 0 16 0.001200669 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FANCONI_ANEMIA_PATHWAY 19 11 BRCA2;FANCA;FANCB;FANCC;FANCD2;FANCE;FANCG;FANCL;RPS27A;UBE2T;USP1 REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX 0.700485334 1.970746463 0 16 3.07E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX 48 35 CDC6;CDT1;GMNN;MCM8;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 0.683127199 1.918977267 0 16 0.001199955 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 46 31 PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 0.642031959 1.967433673 0 16 2.98E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 77 40 ANAPC1;AURKA;AURKB;BUB1B;CCNA1;CCNA2;CCNB1;CDC20;CDK1;CDK2;CUL1;FBXO5;MAD2L1;PLK1;PSMA2;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;PTTG1;RPS27A;SKP2;UBE2C;UBE2D1 REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX 0.728839557 2.117272039 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX 57 38 CDC6;CDT1;E2F1;E2F2;E2F3;GMNN;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;PSME4;RPS27A;UBA52 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 0.581852669 1.809493147 0 16 0.00579326 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 81 47 EIF4G1;ELAVL1;EXOSC2;EXOSC3;EXOSC4;EXOSC5;EXOSC6;EXOSC8;EXOSC9;HNRNPD;KHSRP;MAPK14;PABPC1;PRKCA;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52;XPO1;YWHAZ REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 0.662383813 1.895300385 0 16 0.001577549 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 50 34 EIF4G1;HNRNPD;PABPC1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 0.684763501 2.01612145 0 16 1.68E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 64 41 ANAPC1;AURKA;AURKB;CDC20;PLK1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;PTTG1;RPS27A;SKP2;UBA52;UBE2C;UBE2D1;UBE2E1 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS 0.672749794 1.996548243 0 16 2.20E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS 65 41 ANAPC1;BUB1B;CCNB1;CDC20;CDK1;MAD2L1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;PTTG1;RPS27A;UBA52;UBE2C;UBE2D1;UBE2E1 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C 0.641614961 1.84237727 0 16 0.003424948 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C 56 33 ANAPC1;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;RPS27A;UBA52;UBE2C;UBE2D1;UBE2E1 REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 0.586621711 1.663913216 0.002364066 2.626340368 0.034143515 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 49 34 CDC20;CUL1;FBXO5;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RPS27A;UBA52 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 0.692682958 1.622438842 0.004282655 2.368286886 0.048041158 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 21 7 BUB1B;CDC20;MAD2L1;NEK2;RPS27A;UBE2C;UBE2D1 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 0.64169256 1.844874513 0 16 0.003416538 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 53 32 CCNA1;CCNA2;CCNE1;CCNE2;CDK2;CKS1B;CUL1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMB1;PSMB2;PSMB4;PSMB5;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD14;PSMD2;PSMD4;PSMD7;RPS27A;SKP2;UBA52 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G 0.685077606 1.920599738 0 16 0.001137707 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G 47 32 PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4;RBX1;RPS27A;UBA52 KEGG_SPLICEOSOME 0.575735295 1.914277837 0 16 0.001229954 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SPLICEOSOME 111 59 BCAS2;BUD31;CDC5L;CHERP;CWC15;DHX16;DHX38;EFTUD2;EIF4A3;HNRNPA3;ISY1;LSM2;LSM4;LSM6;LSM7;MAGOH;MAGOHB;NAA38;NCBP1;PCBP1;PHF5A;PLRG1;PPIE;PPIH;PPIL1;PQBP1;PRPF18;PRPF3;PRPF38A;PRPF38B;PRPF40A;PUF60;RBM17;RBM8A;SART1;SF3A3;SF3B2;SF3B3;SF3B4;SF3B5;SMNDC1;SNRNP40;SNRPA;SNRPA1;SNRPB;SNRPB2;SNRPC;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;TCERG1;THOC1;TRA2B;TXNL4A;U2AF1;USP39 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 0.660396771 1.627467155 0.012931034 1.888366731 0.047386163 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 23 16 CLP1;CPSF1;CPSF3;CPSF7;CSTF3;LSM10;NCBP1;NUDT21;PABPN1;SLBP;SNRPB;SNRPD3;SNRPE;SNRPF;SNRPG;ZNF473 REACTOME_MRNA_3_END_PROCESSING 0.674566358 1.70640573 0.004385965 2.357934848 0.022682635 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_3_END_PROCESSING 24 15 CLP1;CPSF1;CPSF3;CPSF7;CSTF3;DHX38;MAGOH;NCBP1;NUDT21;PABPN1;RBM8A;RNPS1;SRRM1;U2AF1;UPF3B REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0.693296337 1.852935897 0 16 0.003156881 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 33 23 CLP1;CPSF1;CPSF3;CPSF7;CSTF3;DHX38;LSM10;MAGOH;NCBP1;NUDT21;PABPN1;RBM8A;RNPS1;SLBP;SNRPB;SNRPD3;SNRPE;SNRPF;SNRPG;SRRM1;U2AF1;UPF3B;ZNF473 PID_FANCONI_PATHWAY 0.656563759 1.835899289 0 16 0.003801675 http://www.broadinstitute.org/gsea/msigdb/cards/PID_FANCONI_PATHWAY 42 20 BLM;BRCA2;BRIP1;CHEK1;FANCA;FANCB;FANCC;FANCD2;FANCE;FANCG;FANCI;FANCL;H2AFX;RFC2;RFC3;RFC4;RPA1;TOPBP1;UBE2T;USP1 PID_ATR_PATHWAY 0.666870744 1.796593054 0 16 0.006911993 http://www.broadinstitute.org/gsea/msigdb/cards/PID_ATR_PATHWAY 39 20 BRCA2;CCNA2;CDC25A;CDC25C;CDC6;CDK2;CHEK1;CLSPN;FANCD2;MCM2;MCM7;PLK1;RAD51;RFC2;RFC3;RFC4;RPA1;TIPIN;TOPBP1;YWHAZ REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS 0.774243821 2.001520901 0 16 2.37E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS 29 19 CDC25A;CDC25C;CDC45;CDC6;CDC7;CHEK1;DBF4;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8;RFC2;RFC3;RFC4;RPA1 REACTOME_G2_M_CHECKPOINTS 0.79967811 2.151474891 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G2_M_CHECKPOINTS 35 21 CCNB1;CCNB2;CDC25A;CDC25C;CDC45;CDC6;CDC7;CDK1;CHEK1;CHEK2;DBF4;MCM10;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;RFC2;RFC3;RFC4 KEGG_CELL_CYCLE 0.695154783 2.287110971 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CELL_CYCLE 118 53 BUB1;BUB1B;CCNA2;CCNB1;CCNB2;CCNE1;CCNE2;CDC20;CDC25A;CDC25B;CDC25C;CDC45;CDC6;CDC7;CDK1;CDK4;CDK6;CDKN2A;CDKN2C;CHEK1;CHEK2;CUL1;DBF4;E2F1;E2F2;E2F3;E2F4;E2F5;ESPL1;HDAC2;MAD2L1;MAD2L2;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MYC;PCNA;PKMYT1;PLK1;PRKDC;PTTG1;RAD21;RBL1;SKP2;SMC1B;TFDP1;TFDP2;TTK;YWHAQ;YWHAZ PID_BARD1_PATHWAY 0.739998514 1.892357399 0 16 0.001665562 http://www.broadinstitute.org/gsea/msigdb/cards/PID_BARD1_PATHWAY 28 13 CCNE1;CDK2;FANCA;FANCC;FANCD2;FANCE;FANCG;FANCL;PCNA;PRKDC;RAD51;TOPBP1;XRCC6 REACTOME_G0_AND_EARLY_G1 0.804784761 2.004732756 0 16 2.46E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G0_AND_EARLY_G1 23 15 CCNA2;CCNE1;CCNE2;CDC25A;CDC6;CDK1;CDK2;E2F1;E2F4;E2F5;LIN9;MYBL2;PCNA;RBL1;TFDP1 BIOCARTA_MCM_PATHWAY 0.839090733 1.755712074 0.002164502 2.664641976 0.012666926 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_MCM_PATHWAY 12 9 CCNE1;CDC6;CDT1;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7 REACTOME_UNWINDING_OF_DNA 0.886501032 1.816521263 0 16 0.005158463 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNWINDING_OF_DNA 11 10 CDC45;GINS1;GINS4;MCM2;MCM3;MCM4;MCM5;MCM6;MCM7;MCM8 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE 0.757398026 1.649824568 0.017241379 1.763427994 0.038174978 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE 13 7 BANF1;CXCR4;FEN1;HMGA1;PPIA;PSIP1;XRCC6 REACTOME_METABOLISM_OF_NON_CODING_RNA 0.651069253 1.869922594 0 16 0.002436254 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NON_CODING_RNA 46 28 CLNS1A;GEMIN4;GEMIN6;NCBP1;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;RAE1;SEH1L;SNRPB;SNRPD1;SNRPD2;SNRPD3;SNRPE;SNRPF;SNRPG;TGS1;WDR77 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0.69835845 1.998303868 0 16 2.28E-04 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 42 22 CPSF1;CPSF3;DHX38;MAGOH;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;RBM8A;SEH1L;SLBP;SRRM1;U2AF1;UPF3B REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 0.66785167 1.774962025 0 16 0.009922735 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 31 16 CPSF1;CPSF3;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;SEH1L KEGG_PROTEASOME 0.689636186 1.93273604 0 16 7.88E-04 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PROTEASOME 43 30 IFNG;POMP;PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES 0.655603627 1.846558492 0 16 0.003392292 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES 47 29 PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA7;PSMA8;PSMB1;PSMB2;PSMB4;PSMB5;PSMB6;PSMB7;PSMB9;PSMC1;PSMC2;PSMC3;PSMC4;PSMD1;PSMD10;PSMD11;PSMD12;PSMD13;PSMD14;PSMD2;PSMD4;PSMD7;PSMD8;PSME4 PID_AURORA_B_PATHWAY 0.812844979 2.25922577 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/PID_AURORA_B_PATHWAY 38 19 AURKA;AURKB;BIRC5;BUB1;CDCA8;CENPA;INCENP;KIF20A;KIF23;KIF2C;NCAPD2;NCAPG;NCAPH;NCL;NDC80;PPP2R5D;RACGAP1;SMC4;STMN1 KEGG_ALLOGRAFT_REJECTION 0.649525442 1.789328686 0 16 0.007823872 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ALLOGRAFT_REJECTION 35 18 CD40;CD80;CD86;FAS;FASLG;GZMB;HLA-A;HLA-B;HLA-DOB;HLA-E;HLA-F;HLA-G;IFNG;IL10;IL12A;IL12B;PRF1;TNF KEGG_GRAFT_VERSUS_HOST_DISEASE 0.683077086 1.870560248 0.002207506 2.656098203 0.002484024 http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GRAFT_VERSUS_HOST_DISEASE 37 23 CD80;CD86;FAS;FASLG;GZMB;HLA-A;HLA-B;HLA-DOB;HLA-E;HLA-F;HLA-G;IFNG;IL1A;IL1B;IL6;KIR2DL1;KIR2DL3;KIR3DL1;KIR3DL2;KLRC1;KLRD1;PRF1;TNF BIOCARTA_CYTOKINE_PATHWAY 0.688718444 1.692109959 0.012847966 1.891165631 0.025590972 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_CYTOKINE_PATHWAY 20 12 IFNB1;IFNG;IL10;IL12A;IL12B;IL13;IL15;IL18;IL1A;IL6;LTA;TNF BIOCARTA_IL12_PATHWAY 0.672602703 1.635503971 0.008130081 2.089905112 0.044847757 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_IL12_PATHWAY 21 16 CCR5;CD247;CD3D;CD3E;CD3G;CXCR3;ETV5;IFNG;IL12A;IL12B;IL12RB1;IL12RB2;IL18;IL18R1;MAP2K6;MAPK14 BIOCARTA_ACTINY_PATHWAY 0.723590402 1.737844236 0.004347826 2.361727837 0.015755863 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_ACTINY_PATHWAY 20 12 ACTR2;ACTR3;ARPC1A;ARPC1B;ARPC2;ARPC4;ARPC5;NCK1;PIR;PSMA7;WASF1;WASF3 PID_FOXM1_PATHWAY 0.709299334 1.956591504 0 16 4.34E-04 http://www.broadinstitute.org/gsea/msigdb/cards/PID_FOXM1_PATHWAY 40 23 AURKB;BIRC5;BRCA2;CCNA2;CCNB1;CCNB2;CCNE1;CDC25B;CDK1;CDK2;CDK4;CDKN2A;CENPA;CENPF;CHEK2;CKS1B;ETV5;FOXM1;MYC;NEK2;PLK1;SKP2;TGFA REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 0.768736919 1.692576829 0.004201681 2.376576958 0.02565523 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 15 10 CCNA2;CCNB1;CCNB2;CDC25A;CDC25B;CDC25C;CDK1;PKMYT1;PLK1;XPO1 SA_G2_AND_M_PHASES 0.855752831 1.627329201 0.006493506 2.187520722 0.047032124 http://www.broadinstitute.org/gsea/msigdb/cards/SA_G2_AND_M_PHASES 8 4 CDC25A;CDC25B;CDK1;CHEK1 BIOCARTA_G2_PATHWAY 0.741980565 1.856977394 0 16 0.00299006 http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_G2_PATHWAY 24 9 CCNB1;CDC25A;CDC25B;CDC25C;CDK1;CHEK1;CHEK2;PLK1;YWHAQ PID_AURORA_A_PATHWAY 0.754942525 2.013209358 0 16 1.60E-04 http://www.broadinstitute.org/gsea/msigdb/cards/PID_AURORA_A_PATHWAY 30 10 AURKA;AURKB;BIRC5;CDC25B;CENPA;DLGAP5;PPP2R5D;RAN;TACC3;TPX2 PID_PLK1_PATHWAY 0.804993025 2.261761035 0 16 0 http://www.broadinstitute.org/gsea/msigdb/cards/PID_PLK1_PATHWAY 42 20 AURKA;BUB1;BUB1B;CCNB1;CDC20;CDC25B;CDC25C;CDK1;CENPE;CLSPN;ERCC6L;FBXO5;INCENP;KIF20A;NDC80;PLK1;PPP1CB;PRC1;SPC24;TPX2 SA_REG_CASCADE_OF_CYCLIN_EXPR 0.751341262 1.61544276 0.020746888 1.683047039 0.049848124 http://www.broadinstitute.org/gsea/msigdb/cards/SA_REG_CASCADE_OF_CYCLIN_EXPR 13 10 CCNA1;CCNA2;CCNE1;CCNE2;CDK2;CDK4;CDKN2A;E2F1;E2F2;E2F4 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0.699205147 1.854554145 0 16 0.003127001 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 31 18 BANF1;HMGA1;NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;PSIP1;SEH1L;SLC25A5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 0.617823061 1.848579481 0 16 0.003347087 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 59 40 B2M;CD19;CD226;CD247;CD3D;CD3E;CD3G;CD40;CD8A;CD8B;CD96;CXADR;FCGR2B;HCST;HLA-A;HLA-B;HLA-F;HLA-G;ICAM1;ICAM2;ICAM4;ITGB1;ITGB2;ITGB7;KIR2DL1;KIR2DL3;KIR2DL4;KIR3DL1;KIR3DL2;KLRC1;KLRD1;LILRB1;LILRB2;LILRB3;LILRB4;PVR;ULBP1;ULBP2;ULBP3;VCAM1 REACTOME_PHOSPHORYLATION_OF_THE_APC_C 0.724214233 1.622137629 0.01059322 1.974971995 0.047771816 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHORYLATION_OF_THE_APC_C 17 4 CCNB1;CDK1;PLK1;UBE2C REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0.579376931 1.702930142 0.002202643 2.657055854 0.023131516 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 56 14 CENPA;CENPH;CENPI;CENPK;CENPN;CENPO;CENPQ;H2AFX;H2AFZ;HIST1H2BJ;HIST1H4C;HJURP;OIP5;RUVBL1 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0.6838529 1.619774061 0.012847966 1.891165631 0.048511424 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 19 12 CCT3;CCT4;CCT5;CCT6A;CCT7;CCT8;TCP1;TUBA1B;TUBA1C;TUBA4A;TUBB3;TUBB6 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY 0.702285004 1.760878071 0 16 0.011814029 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY 26 16 NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;RAN;SEH1L;XPO1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 0.67585102 1.712465058 0 16 0.021053914 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 26 14 NUP107;NUP153;NUP155;NUP205;NUP37;NUP50;NUP54;NUP62;NUP85;NUP88;NUP93;NUPL2;POM121;SEH1L REACTOME_KINESINS 0.754529453 1.867167735 0 16 0.002668767 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KINESINS 24 10 KIF11;KIF15;KIF18A;KIF20A;KIF23;KIF2C;KIF4A;KIF4B;KIFC1;RACGAP1