This PDF file includes:

• Fig. S1. HPAC strongly binds to HSV-1 GFP virus.
• Fig. S2. Extracellular virus–based plaque assay for HPAC therapy.
• Fig. S3. HPAC does not cause a loss in visual acuity by blocking light.
• Fig. S4. HPAC does not elevate interferons in HCEs.
• Fig. S5. HPAC does not elevate interferons in HFFs.
• Fig. S6. DECON is effective when added 24 hours after infection.
• Fig. S7. DECON protects the murine cornea from HSV-1 infection.
• Fig. S8. Graphical abstract showing DECON protecting cells against viral infection.
• Fig. S9. Full-length blots for the Western blot shown in Fig. 1 (G and H).
• Fig. S10. Full-length blots for the Western blot shown in Fig. 3D.

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