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["Tbale S4Differences in relative abundant of  at the species level between CA and CS groups by LEfSe analysis."]
["Species name (Species)","group","Mean","LDA_value","P value"]
["uncultured_organism_g__Ruminiclostridium_5","CS",3.0955969778,2.79832561347,0.00414165780395]
["Coelastrella_sp__M60_g__norank","CS",3.65069894019,3.36005558227,0.00152888247443]
["Romboutsia_lituseburensis","CS",3.31528236313,3.00124363149,0.00414165780395]
["unclassified_g__Ruminiclostridium_5","CS",3.80258495415,3.49452237729,0.00434475251435]
["unclassified_f__Ruminococcaceae","CS",4.81772994265,4.35794351612,0.018532974877]
["Gordonia_hydrophobica","CS",4.15288025807,3.85103062097,0.00320978585132]
["uncultured_Clostridiaceae_bacterium_g__Ruminococcaceae_UCG_013","CS",2.79186108876,2.51415167733,0.00152888247443]
["unclassified_g__Anaerotruncus","CS",3.96831410917,3.64168527252,0.00448325040209]
["unclassified_g__Bacillus","CS",4.73050588074,4.43883608997,0.00414165780395]
["Nakamurella_multipartita_DSM_44233","CS",1.79186108876,2.32312885563,0.00135455314025]
["unclassified_g___Eubacterium__coprostanoligenes_group","CS",2.62913379126,2.28304235744,0.00393419850926]
["unclassified_g__Lachnospiraceae_UCG_010","CS",1.49083109309,2.08443163383,0.0247684900093]
["unclassified_g__Eggerthella","CS",2.94184954525,2.65966058299,0.00152888247443]
["Cellulosimicrobium_cellulans_g__Cellulosimicrobium","CS",2.9456759531,2.65326742608,0.00152888247443]
["Ruminococcaceae_bacterium_GD6","CS",2.63695912877,2.35898871564,0.0144945031748]
["Bilophila_wadsworthia","CS",3.88746626008,3.5798739085,0.00241594115435]
["Clostridiaceae_bacterium_GM1","CS",3.51098512473,3.17150899021,0.00441369134212]
["uncultured_bacterium_g__Kaistia","CS",2.14404360687,2.04356676245,0.0014929176184]
["unclassified_g__Subdoligranulum","CS",2.52223955735,2.23208009082,0.00320978585132]
["uncultured_bacterium_g__Amaricoccus","CS",1.96795234781,2.31067263611,0.00138832559605]
["unclassified_g__norank_o__Mollicutes_RF9","CS",3.74246931354,3.43252001138,0.00315259641363]
["unclassified_g__Catabacter","CS",2.3801327956,2.00093927422,0.0250981529264]
["Watanabea_reniformis","CS",2.35116909966,2.17685208771,0.0014929176184]
["unclassified_g__Clostridium_sensu_stricto_1","CS",3.79618246254,3.50075279414,0.00394414491981]
["unclassified_g__Caproiciproducens","CS",3.19196715919,2.8500871929,0.00696463552347]
["uncultured_soil_bacterium_g__Planktothrix","CS",2.30374444974,2.05302205701,0.00682365087822]
["uncultured_alpha_proteobacterium_g__Candidatus_Hepatincola","CS",3.27437737536,2.97487820892,0.00152888247443]
["uncultured_bacterium_g__Candidatus_Soleaferrea","CS",2.59634127786,2.31715969568,0.00423210193893]
["unclassified_g__Ochrobactrum","CS",2.95322909099,2.54208344003,0.0380820071524]
["Monoraphidium_neglectum","CS",2.74002945048,2.46969232531,0.00152888247443]
["unclassified_g__norank_f__Clostridiales_vadinBB60_group","CS",3.38431543931,3.02713431661,0.0177191201139]
["unclassified_g__Parabacteroides","CS",5.19177265542,4.7013984281,0.0423570620269]
["unclassified_g__Phascolarctobacterium","CS",4.34498525712,4.02708898043,0.00381556895664]
["_Clostridium__propionicum_DSM_1682","CS",2.5877411061,2.2934378725,0.00405919636556]
["Anaerofustis_stercorihominis_DSM_17244","CS",2.39392108009,2.15011696139,0.0050317823743]
["uncultured_bacterium_g__Ruminiclostridium_5","CS",2.76958469405,2.43892694263,0.00375221010087]
["Pseudomonas_veronii","CS",2.51202039216,2.20159115173,0.0289338616689]
["unclassified_g__Ruminococcaceae_UCG_013","CS",2.96431806316,2.6764807321,0.00152888247443]
["unclassified_g__Rhizobium","CS",2.2109903965,2.28024577061,0.00308828687815]
["unclassified_g__Ruminococcaceae_UCG_014","CS",3.57807996089,3.14795021262,0.018532974877]
["uncultured_bacterium_g__Coprococcus_1","CS",3.07346253258,2.76330757264,0.00375221010087]
["uncultured_bacterium_g___Eubacterium__coprostanoligenes_group","CS",4.00835687673,3.67851135581,0.0112452719358]
["unclassified_g__Nostoc","CS",2.14404360687,2.0222796251,0.0014929176184]
["Nannochloropsis_oceanica_g__norank","CS",1.96795234781,2.25823350287,0.0247684900093]
["uncultured_Firmicutes_bacterium_g__Candidatus_Soleaferrea","CS",2.33592913311,2.05141180388,0.00682365087822]
["unclassified_g__norank_f__Family_XIII","CS",2.26898234348,2.0112361322,0.0370312911428]
["Mycobacterium_arupense","CS",2.30374444974,2.14268649985,0.0014929176184]
["unclassified_g__Hydrogenoanaerobacterium","CS",3.6983308164,3.37026483243,0.00420873574574]
["Mycobacterium_poriferae","CS",2.78086570446,2.5074112667,0.00375221010087]
["unclassified_g__Stenotrophomonas","CS",2.76958469405,2.3756761212,0.0175179858336]
["uncultured_bacterium_g__norank_o__Mollicutes_RF9","CS",3.42152548076,3.07058142912,0.00726839996268]
["uncultured_bacterium_g__Tyzzerella","CS",2.72128001447,2.41947893987,0.00152888247443]
["unclassified_g__Mycobacterium","CS",2.69495107575,2.43615266484,0.0014929176184]
["unclassified_f__FamilyI_o__SubsectionIV","CS",2.7461035982,2.50272126333,0.00152888247443]
["Clostridium_sp__SL_2013_71","CS",3.38292569578,3.08474490121,0.00320978585132]
["Arcobacter_butzleri","CS",3.97441839006,3.62597647629,0.0146176463144]
["unclassified_g__norank_f__FamilyI_o__SubsectionIV","CS",3.44265412841,3.16981940212,0.0014929176184]
["Lactococcus_piscium","CS",4.17342738455,3.88421730766,0.00152888247443]
["Rhodococcus_koreensis","CS",2.43283914612,2.22844298243,0.00145750501698]
["unclassified_g__Streptococcus","CS",3.08467075418,2.7853573836,0.00241594115435]
["uncultured_Firmicutes_bacterium_g__norank_f__Lachnospiraceae","CS",2.62116486159,2.34462628787,0.00682365087822]
["unclassified_g__norank_c__Cyanobacteria","CS",2.47983570879,2.27421682205,0.0299129903208]
["uncultured_bacterium_g__Anaerotruncus","CS",2.95695696351,2.64181943324,0.0023678495363]
["Nostoc_calcicola_99","CS",1.66692235215,2.15070913124,0.0247684900093]
["uncultured_Firmicutes_bacterium_g__Ruminococcaceae_UCG_014","CS",3.24095361988,2.93299275479,0.00686489889478]
["unclassified_f__Christensenellaceae","CS",2.11922002314,2.05129089712,0.00668681827747]
["unclassified_g__Candidatus_Protochlamydia","CS",1.5877411061,2.36459151133,0.00628518164338]
["unclassified_g__Escherichia_Shigella","CS",3.99801207035,3.70905530202,0.00434475251435]
["unclassified_g__Tyzzerella_3","CS",2.90160832647,2.60496198135,0.0252065695531]
["unclassified_g__Paenibacillus","CS",2.11922002314,2.14447064606,0.0014929176184]
["unclassified_g__Methylobacterium","CS",2.67410093678,2.3907925888,0.00309602054996]
["Bacillus_endoradicis","CS",2.62116486159,2.36852088877,0.0014929176184]
["Eggerthellaceae_bacterium_Marseille_P2849","CS",3.10095870617,2.7384480718,0.00696463552347]
["Rhodococcus_hoagii","CS",3.80837212555,3.50495262945,0.00241594115435]
["Clostridium_sp__ND2","CS",3.77356646571,3.47267159161,0.00241594115435]
["uncultured_bacterium_g__Hydrogenoanaerobacterium","CS",2.47983570879,2.20366791735,0.00152888247443]
["uncultured_Bacteroidia_bacterium_g__Dysgonomonas","CS",3.56179200889,3.27237632539,0.00152888247443]
["Castanea_mollissima__Chinese_chestnut__g__norank","CS",3.1512221915,2.88414312001,0.00145750501698]
["unclassified_g__Bosea","CS",2.28671111044,2.08833997699,0.00314816970308]
["unclassified_g__Weissella","CS",3.20263832213,2.89008188638,0.00320978585132]
["Clostridium_sp__Marseille_P2434","CS",3.10625504598,2.83555489498,0.0014929176184]
["Bacillus_aerophilus","CS",2.50155495849,2.24071890752,0.0014929176184]
["Geobacillus_stearothermophilus_g__Geobacillus","CS",2.36589235649,2.13580338024,0.0014929176184]
["Coccomyxa_subellipsoidea_C_169","CS",1.79186108876,2.22213336802,0.00655146011355]
["unclassified_g__Carnobacterium","CS",3.03178590202,2.74605328188,0.00152888247443]
["Nannocystis_pusilla","CS",1.84301361121,2.7556926149,0.0247684900093]
["uncultured_bacterium_g__Dysgonomonas","CS",3.050139104,2.75430291265,0.0252065695531]
["Sphingobacterium_multivorum","CS",2.47983570879,2.23175114993,0.00668681827747]
["uncultured_soil_bacterium_g__norank_o__HTA4","CS",2.03489913744,2.14686480476,0.0014929176184]
["unclassified_g__Tyzzerella","CS",2.30374444974,2.02965416684,0.00535668492287]
["Providencia_alcalifaciens","CA",3.07102266953,2.83619914444,0.0464795537198]
["unclassified_g__Hafnia_Obesumbacterium","CA",3.20653605507,3.01371528541,0.0173177954996]
["unclassified_g__Bilophila","CA",3.27539744508,2.91415422957,0.0235941234858]
["uncultured_Verrucomicrobia_bacterium_g__Akkermansia","CA",3.69688557553,3.35502523268,0.00931441089103]
["uncultured_bacterium_g__Bacteroides","CA",4.46904422819,4.10013183398,0.0118293801095]
["unclassified_g__Butyricimonas","CA",3.53010354061,3.19064957547,0.0235941234858]
["unclassified_f__Porphyromonadaceae","CA",2.81082892783,2.58203338085,0.0232919350062]
["uncultured_bacterium_g__Alistipes","CA",4.41195994665,4.14977330992,0.00320978585132]
["gut_metagenome_g__norank_f__Rhodospirillaceae","CA",3.11555506906,2.72857028613,0.00931441089103]
["uncultured_Verrucomicrobiaceae_bacterium_g__Akkermansia","CA",3.71112601464,3.34553551866,0.00931441089103]
["unclassified_f__Micrococcaceae","CA",2.65645691847,2.47651647873,0.00590964695446]
["unclassified_g__Rikenella","CA",2.40540089777,2.07525611372,0.0235941234858]
["unclassified_g__Elizabethkingia","CA",3.20802591754,3.03717338682,0.00931441089103]
["uncultured_bacterium_g__Odoribacter","CA",3.18512283515,2.82450956574,0.00931441089103]
["unclassified_f__Prevotellaceae","CA",3.66847064071,3.26853207921,0.0235941234858]
["Flavobacterium_oncorhynchi","CA",3.18512283515,3.00044673722,0.00917432965159]
["unclassified_f__Erysipelotrichaceae","CA",4.07568709591,3.51977075892,0.0183281257228]
["unclassified_g__norank_f__Bacteroidales_S24_7_group","CA",3.15426277205,2.85694436095,0.00931441089103]
["Leuconostoc_pseudomesenteroides","CA",2.88565786634,2.58457843264,0.0299129903208]
["Arthrobacter_psychrolactophilus","CA",4.37973233962,4.17115775408,0.00381556895664]
["unclassified_g__Alistipes","CA",4.12735480903,3.77316432922,0.00320978585132]
["uncultured_prokaryote_g__Vogesella","CA",2.68712573824,2.34194686437,0.00917432965159]
["Morganella_morganii_subsp__morganii_KT","CA",4.04842421734,3.72412766977,0.0118293801095]
["Anaerorhabdus_furcosa","CA",3.94019927924,3.63316969277,0.0111014269985]
["unclassified_g__Chryseobacterium","CA",3.5279729011,3.31709878349,0.00931441089103]
["unclassified_g__Odoribacter","CA",3.54678249842,3.18928757634,0.0235941234858]
["unclassified_f__Rikenellaceae","CA",3.93241402243,3.6249565945,0.0235941234858]
["Myroides_marinus","CA",4.50306554951,4.31145974424,0.0235941234858]
["unclassified_f__Veillonellaceae","CA",4.13428376958,3.91126389514,0.00931441089103]
["Vagococcus_fluvialis","CA",4.9389298149,4.49118252945,0.00320978585132]
["Alistipes_sp__CHKCI003","CA",2.69203307273,2.57120658474,0.0223939052621]
["uncultured_bacterium_g__Cetobacterium","CA",3.35754028212,3.01381667369,0.0146176463144]
["Rikenella_microfusus_DSM_15922","CA",2.20504106399,2.01480697903,0.0223939052621]
["Ruminococcus_sp__Marseille_P2780",null,1.5877411061,null,"-"]
["Pseudomonas_psychrotolerans",null,0,null,"-"]
["unclassified_g__Acinetobacter",null,4.16474022922,null,"-"]
["uncultured_bacterium_g__norank_o__JG30_KF_CM45",null,2.00271445407,null,0.0142816190677]
["Auxenochlorella_protothecoides_g__norank",null,1.88877110177,null,"-"]
["Shewanella_decolorationis",null,2.06486236082,null,"-"]
["Serratia_fonticola",null,0.888771101766,null,"-"]
["unclassified_g__Ruminiclostridium_9",null,2.36589235649,null,"-"]
["unclassified_f__Flavobacteriaceae",null,0,null,"-"]
["Sphingobium_xenophagum",null,1.04367306175,null,"-"]
["uncultured_bacterium_g__Erysipelatoclostridium",null,4.04215036479,null,"-"]
["uncultured_Verrucomicrobia_bacterium_g__norank_o__Opitutae_vadinHA64",null,0,null,"-"]
["unclassified_g___Anaerorhabdufurcosa_group",null,1.21976432081,null,"-"]
["unclassified_o__Sphingobacteriales",null,0,null,"-"]
["uncultured_organism_g__Ruminococcaceae_NK4A214_group",null,1.52079431647,null,"-"]
["Lactobacillus_intestinalis",null,2.3224266627,null,"-"]
["Leucobacter_salsicius_M1_8",null,2.20504106399,null,"-"]
["Clostridium_sp__enrichment_culture_clone_06_1235251_143",null,0,null,"-"]
["uncultured_rumen_bacterium_4C0d_17",null,1.18980109743,null,"-"]
["unclassified_g__Anaerosinus",null,2.26115700597,null,"-"]
["uncultured_bacterium_g__norank_f__FFCH7168",null,1.04367306175,null,"-"]
["unclassified_g__Paracoccus",null,1.66692235215,null,"-"]
["Comamonas_testosteroni_TK102",null,2.72491429913,null,"-"]
["Sphingobacterium_spiritivorum",null,1.04367306175,null,"-"]
["unclassified_g__Lactobacillus",null,2.71112601464,null,"-"]
["Paraburkholderia_fungorum",null,2.02139666704,null,"-"]
["unclassified_g__norank_f__Acidaminococcaceae",null,0,null,"-"]
["uncultured_Clostridium_sp__g__Anaerosporobacter",null,2.80258495415,null,"-"]
["unclassified_g__Pseudomonas",null,4.41594050585,null,"-"]
["unclassified_g__Aeromonas",null,4.10569066061,null,"-"]
["unclassified_g__Butyricicoccus",null,2.26898234348,null,"-"]
["Acinetobacter_rudis_CIP_110305",null,1.04367306175,null,"-"]
["bacterium_Ellin5121",null,0,null,"-"]
["uncultured_rumen_bacterium_g__norank_f__Rhodospirillaceae",null,0,null,"-"]
["uncultured_bacterium_g__Taibaiella",null,1.44161307042,null,"-"]
["Methylobacterium_aquaticum",null,1.04367306175,null,"-"]
["unclassified_f__Flammeovirgaceae",null,0,null,"-"]
["uncultured_bacterium_g__norank_f__Peptococcaceae",null,2.49083109309,null,"-"]
["uncultured_Clostridiales_bacterium_g__Ruminococcaceae_UCG_005",null,1.44161307042,null,"-"]
["uncultured_bacterium_g__Bilophila",null,3.43637001501,null,"-"]
["uncultured_bacterium_g__Peptostreptococcus",null,1.94676304874,null,"-"]
["unclassified_g__Gordonibacter",null,2.80784919414,null,"-"]
["uncultured_bacterium_g__Acidisphaera",null,0,null,"-"]
["uncultured_Rikenellaceae_bacterium_g__Rikenella",null,2.60596592621,null,"-"]
["uncultured_bacterium_g__norank_f__Porphyromonadaceae",null,0,null,"-"]
["unclassified_g__norank_p__Atribacteria",null,1.44161307042,null,"-"]
["unclassified_g__Peptoclostridium",null,3.90076421643,null,"-"]
["gut_metagenome_g__norank_f__Flavobacteriaceae",null,1.52079431647,null,"-"]
["uncultured_bacterium_g__Faecalibacterium",null,1.52079431647,null,"-"]
["unclassified_g__Novosphingobium",null,0.742643066088,null,"-"]
["uncultured_Peptococcaceae_bacterium_g__norank_o__Selenomonadales",null,3.34143357285,null,"-"]
["bacterium_enrichment_culture_clone_B213_2011_",null,0,null,"-"]
["uncultured_bacterium_g__Succinispira",null,2.75548029079,null,"-"]
["uncultured_bacterium_g__Coprobacillus",null,3.64005020575,null,"-"]
["Brevundimonas_nasdae",null,1.5877411061,null,"-"]
["uncultured_bacterium_g__Parabacteroides",null,0,null,"-"]
["unclassified_f__Geodermatophilaceae",null,1.36589235649,null,"-"]
["uncultured_alpha_proteobacterium_g__norank_f__Rickettsiales_Incertae_Sedis",null,0,null,"-"]
["unclassified_o__Clostridiales",null,2.28671111044,null,"-"]
["unclassified_g__norank_f__Rhodospirillaceae",null,3.02594429479,null,"-"]
["unclassified_g__Faecalitalea",null,4.67562388801,null,"-"]
["uncultured_bacterium_g__Candidatus_Saccharimonas",null,1.74264306609,null,"-"]
["unclassified_g__Desulfovibrio",null,2.95483067049,null,"-"]
["Plantibacter_flavus_g__Plantibacter",null,1.94676304874,null,"-"]
["unclassified_g__Agromyces",null,1.79186108876,null,0.0247684900093]
["uncultured_bacterium_g__Oxalobacter",null,2.26898234348,null,"-"]
["unclassified_g__norank_f__Rickettsiales_Incertae_Sedis",null,0,null,"-"]
["uncultured_Firmicutes_bacterium_g__Ruminococcaceae_NK4A214_group",null,0,null,"-"]
["uncultured_Eubacteriaceae_bacterium_g___Eubacterium__brachy_group",null,2.81452507339,null,"-"]
["Cryptosporangium_japonicum",null,0,null,"-"]
["uncultured_rumen_bacterium_g__Acetanaerobacterium",null,0,null,"-"]
["unclassified_g__Sphingomonas",null,1.52079431647,null,"-"]
["uncultured_organism_g__norank_f__Clostridiales_vadinBB60_group",null,2.02139666704,null,"-"]
["Acinetobacter_bohemicus_ANC_3994",null,0,null,"-"]
["unclassified_o__Selenomonadales",null,1.44161307042,null,"-"]
["uncultured_bacterium_g__norank_o__P_palmC41",null,0,null,"-"]
["uncultured_Comamonas_sp__g__Comamonas",null,2.33370767311,null,"-"]
["unclassified_p__Firmicutes",null,1.21976432081,null,"-"]
["uncultured_organism_g__Ruminococcaceae_UCG_014",null,1.64573305308,null,"-"]
["unclassified_g__Parasutterella",null,1.04367306175,null,"-"]
["Sphingobium_yanoikuyae",null,0,null,"-"]
["unclassified_g__Coprobacter",null,2.1228543078,null,"-"]
["uncultured_bacterium_g__Singulisphaera",null,1.49083109309,null,"-"]
["unclassified_g__norank_f__Christensenellaceae",null,2.16752470272,null,0.00152888247443]
["uncultured_bacterium_g__Ruminococcaceae_UCG_014",null,2.35542692281,null,"-"]
["unclassified_g__Erysipelatoclostridium",null,3.20203555385,null,"-"]
["Sphingomonas_kaistensis",null,1.52079431647,null,"-"]
["Bacteroides_cellulosilyticus",null,2.3801327956,null,"-"]
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["uncultured_bacterium_g__Cereibacter",null,0,null,"-"]
["Jeotgalibacillus_campisalis",null,0,null,"-"]
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["unclassified_g__Ralstonia",null,2.08506574691,null,"-"]
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["unclassified_g__Vibrio",null,0,null,"-"]
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["unclassified_g__Citrobacter",null,5.10940212121,null,"-"]
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["unclassified_o__Micrococcales",null,2.14058307476,null,"-"]
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["Fusobacterium_varium",null,4.11819694969,null,"-"]
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["uncultured_Burkholderiales_bacterium_g__Aquabacterium",null,0,null,"-"]
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